[{"oa":1,"article_processing_charge":"Yes","title":"Chromatin landscape is associated with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome in Artemia franciscana","scopus_import":"1","publication":"Molecular Biology and Evolution","DOAJ_listed":"1","year":"2025","status":"public","_id":"19735","month":"05","publication_identifier":{"issn":["0737-4038"],"eissn":["1537-1719"]},"license":"https://creativecommons.org/licenses/by/4.0/","day":"01","fulldoi":"https://doi.org/10.1093/molbev/msaf085","ddc":["570"],"publisher":"Oxford University Press","OA_place":"publisher","file_date_updated":"2025-05-28T09:34:36Z","doi":"10.1093/molbev/msaf085","pmid":1,"author":[{"last_name":"Bett","full_name":"Bett, Vincent K","id":"57854184-AAE0-11E9-8D04-98D6E5697425","first_name":"Vincent K"},{"last_name":"Trejo Arellano","full_name":"Trejo Arellano, Minerva S","id":"2b681148-eed5-11eb-b81b-ae229e8620f8","orcid":"0000-0002-1982-3475","first_name":"Minerva S"},{"id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz","first_name":"Beatriz","orcid":"0000-0002-4579-8306","last_name":"Vicoso"}],"abstract":[{"text":"The males and females of the brine shrimp Artemia franciscana are highly dimorphic, and this dimorphism is associated with substantial sex-biased gene expression in heads and gonads. How these sex-specific patterns of expression are regulated at the molecular level is unknown. A. franciscana also has differentiated ZW sex chromosomes, with complete dosage compensation, but the molecular mechanism through which compensation is achieved is unknown. Here, we conducted CUT&TAG assays targeting 7 post-translational histone modifications (H3K27me3, H3K9me2, H3K9me3, H3K36me3, H3K27ac, H3K4me3, and H4K16ac) in heads and gonads of A. franciscana, allowing us to divide the genome into 12 chromatin states. We further defined functional chromatin signatures for all genes, which were correlated with transcript level abundances. Differences in the occupancy of the profiled epigenetic marks between sexes were associated with differential gene expression between males and females. Finally, we found a significant enrichment of the permissive H4K16ac histone mark in the Z-specific region in both tissues of females but not males, supporting the role of this histone mark in mediating dosage compensation of the Z chromosome.","lang":"eng"}],"related_material":{"record":[{"status":"public","id":"20449","relation":"dissertation_contains"},{"status":"deleted","id":"20444","relation":"dissertation_contains"}],"link":[{"url":"https://github.com/vkb25/Chromatin-landscape-in-Artemia-franciscana.git","relation":"software"}]},"acknowledged_ssus":[{"_id":"ScienComp"}],"OA_type":"gold","article_number":"msaf085","corr_author":"1","isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Published Version","date_created":"2025-05-25T22:16:56Z","language":[{"iso":"eng"}],"quality_controlled":"1","intvolume":"        42","has_accepted_license":"1","type":"journal_article","date_published":"2025-05-01T00:00:00Z","date_updated":"2026-10-07T22:31:24Z","department":[{"_id":"BeVi"},{"_id":"DaZi"}],"publication_status":"published","file":[{"access_level":"open_access","creator":"dernst","file_size":1282772,"date_created":"2025-05-28T09:34:36Z","success":1,"file_name":"2025_MBE_Bett.pdf","content_type":"application/pdf","checksum":"6c14b03f94b4aadf8869be2c4366d077","relation":"main_file","file_id":"19756","date_updated":"2025-05-28T09:34:36Z"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","acknowledgement":"We thank the Vicoso lab for their help in maintaining Artemia and for their valuable feedback and suggestions. We thank Marwan Elkrewi for his useful technical advice and discussions. We are also grateful to the Scientific Unit at ISTA Austria for computational resources and assistance. This work was supported by Austrian science fund (FWF) grants PAT8748323 and SFB F88-10 (as part of the SFB Meiosis consortium https://sfbmeiosis.org) to BV and Swedish Research Council (Vetenskapsrådet, grant number 2020-06424) to MSTA.","volume":42,"project":[{"_id":"8ed82125-16d5-11f0-9cad-fbcae312235b","grant_number":"PAT 8748323","name":"Sex chromosomes in evolution and development"},{"name":"The highjacking of meiosis for asexual reproduction","grant_number":"F8810","_id":"34ae1506-11ca-11ed-8bc3-c14f4c474396"}],"issue":"5","external_id":{"isi":["001483460200001"],"pmid":["40202086"]},"citation":{"chicago":"Bett, Vincent K, Minerva S Trejo Arellano, and Beatriz Vicoso. “Chromatin Landscape Is Associated with Sex-Biased Expression and Drosophila-like Dosage Compensation of the Z Chromosome in Artemia Franciscana.” <i>Molecular Biology and Evolution</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/molbev/msaf085\">https://doi.org/10.1093/molbev/msaf085</a>.","ieee":"V. K. Bett, M. S. Trejo Arellano, and B. Vicoso, “Chromatin landscape is associated with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome in Artemia franciscana,” <i>Molecular Biology and Evolution</i>, vol. 42, no. 5. Oxford University Press, 2025.","short":"V.K. Bett, M.S. Trejo Arellano, B. Vicoso, Molecular Biology and Evolution 42 (2025).","ista":"Bett VK, Trejo Arellano MS, Vicoso B. 2025. Chromatin landscape is associated with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome in Artemia franciscana. Molecular Biology and Evolution. 42(5), msaf085.","ama":"Bett VK, Trejo Arellano MS, Vicoso B. Chromatin landscape is associated with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome in Artemia franciscana. <i>Molecular Biology and Evolution</i>. 2025;42(5). doi:<a href=\"https://doi.org/10.1093/molbev/msaf085\">10.1093/molbev/msaf085</a>","mla":"Bett, Vincent K., et al. “Chromatin Landscape Is Associated with Sex-Biased Expression and Drosophila-like Dosage Compensation of the Z Chromosome in Artemia Franciscana.” <i>Molecular Biology and Evolution</i>, vol. 42, no. 5, msaf085, Oxford University Press, 2025, doi:<a href=\"https://doi.org/10.1093/molbev/msaf085\">10.1093/molbev/msaf085</a>.","apa":"Bett, V. K., Trejo Arellano, M. S., &#38; Vicoso, B. (2025). Chromatin landscape is associated with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome in Artemia franciscana. <i>Molecular Biology and Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/molbev/msaf085\">https://doi.org/10.1093/molbev/msaf085</a>"}},{"keyword":["gene regulation","networks","omnigenic model","pancreas","collective behaviour"],"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"E-Lib"}],"corr_author":"1","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"18525"}]},"degree_awarded":"PhD","doi_confirm":"1","author":[{"first_name":"Natalia","id":"D2761128-D73D-11E9-A1BF-BA0DE6697425","full_name":"Ruzickova, Natalia","last_name":"Ruzickova"}],"fulldoi":"https://doi.org/10.15479/AT-ISTA-20357","ddc":["570","530"],"OA_place":"publisher","file_date_updated":"2026-09-15T22:30:02Z","doi":"10.15479/AT-ISTA-20357","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-066-4"]},"day":"15","alternative_title":["ISTA Thesis"],"status":"public","_id":"20357","month":"09","year":"2025","article_processing_charge":"No","oa":1,"title":"Effect propagation in biological networks","citation":{"apa":"Ruzickova, N. (2025). <i>Effect propagation in biological networks</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20357\">https://doi.org/10.15479/AT-ISTA-20357</a>","mla":"Ruzickova, Natalia. <i>Effect Propagation in Biological Networks</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20357\">10.15479/AT-ISTA-20357</a>.","ama":"Ruzickova N. Effect propagation in biological networks. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20357\">10.15479/AT-ISTA-20357</a>","ista":"Ruzickova N. 2025. Effect propagation in biological networks. Institute of Science and Technology Austria.","short":"N. Ruzickova, Effect Propagation in Biological Networks, Institute of Science and Technology Austria, 2025.","ieee":"N. Ruzickova, “Effect propagation in biological networks,” Institute of Science and Technology Austria, 2025.","chicago":"Ruzickova, Natalia. “Effect Propagation in Biological Networks.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20357\">https://doi.org/10.15479/AT-ISTA-20357</a>."},"page":"156","supervisor":[{"last_name":"Tkačik","orcid":"0000-0002-6699-1455","first_name":"Gašper","full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87"}],"acknowledgement":"I would also like to acknowledge the Austrian Academy of Sciences for funding through the\r\nDOC Fellowship program (fellowship number 26917), the Grants Office at ISTA for their\r\nassistance with the application, and the Scientific Computing Unit for their support regarding\r\nhigh-performance computation.\r\n","project":[{"_id":"7bec9174-9f16-11ee-852c-ded9fe5f810e","name":"Collective behaviour of cells in pancreatic Islets of Langerhans"}],"file":[{"date_updated":"2026-09-15T22:30:02Z","relation":"source_file","checksum":"0582508d439b233497384f83a8307398","file_id":"22661","file_name":"2025_Ruzickova_Natalia_Thesis.zip","content_type":"application/x-zip-compressed","date_created":"2026-08-07T10:57:05Z","creator":"cchlebak","file_size":56464803,"embargo_to":"open_access","access_level":"closed"},{"file_name":"2025_Ruzickova_Natalia_Thesis.pdf","content_type":"application/pdf","relation":"main_file","checksum":"b722289fd550abede63adc27b9c61784","file_id":"22662","date_updated":"2026-09-15T22:30:02Z","access_level":"open_access","embargo":"2026-09-15","creator":"cchlebak","file_size":30634378,"date_created":"2026-08-07T10:57:34Z"}],"date_updated":"2026-10-02T10:15:31Z","department":[{"_id":"GradSch"},{"_id":"GaTk"}],"publication_status":"published","type":"dissertation","has_accepted_license":"1","date_published":"2025-09-15T00:00:00Z","language":[{"iso":"eng"}],"date_created":"2025-09-15T17:04:48Z","oa_version":"Published Version","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"file_date_updated":"2026-01-01T23:30:03Z","doi":"10.15479/AT-ISTA-20563","OA_place":"publisher","publisher":"Institute of Science and Technology Austria","ddc":["515","519"],"fulldoi":"https://doi.org/10.15479/AT-ISTA-20563","day":"03","publication_identifier":{"issn":["2663-337X"]},"status":"public","_id":"20563","month":"11","year":"2025","alternative_title":["ISTA Thesis"],"title":"Optimal transport methods for kinetic equations, boundary value problems, and discretization of measures","article_processing_charge":"No","oa":1,"corr_author":"1","keyword":["optimal transport","kinetic equations","boundary value problems","quantization","gradient flows","homogenization"],"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"20569"},{"status":"public","relation":"part_of_dissertation","id":"20571"},{"status":"public","relation":"part_of_dissertation","id":"20570"},{"relation":"part_of_dissertation","id":"18706","status":"public"}]},"abstract":[{"lang":"eng","text":"The theory of optimal transport provides an elegant and powerful description of many evolution\r\nequations as gradient flows. The primary objective of this thesis is to adapt and extend the\r\ntheory to deal with important equations that are not covered by the classical framework,\r\nspecifically boundary value problems and kinetic equations. Additionally, we establish new\r\nresults in periodic homogenization for discrete dynamical optimal transport and in quantization\r\nof measures.\r\nSection 1.1 serves as an invitation to the classical theory of optimal transport, including the\r\nmain definitions and a selection of well-established theorems. Sections 1.2-1.5 introduce the\r\nmain results of this thesis, outline the motivations, and review the current state of the art.\r\nIn Chapter 2, we consider the Fokker–Planck equation on a bounded set with positive Dirichlet\r\nboundary conditions. We construct a time-discrete scheme involving a modification of the\r\nWasserstein distance and, under weak assumptions, prove its convergence to a solution of this\r\nboundary value problem. In dimension 1, we show that this solution is a gradient flow in a\r\nsuitable space of measures.\r\nChapter 3 presents joint work with Giovanni Brigati and Jan Maas. We introduce a new theory\r\nof optimal transport to describe and study particle systems at the mesoscopic scale. We prove\r\nadapted versions of some fundamental theorems, including the Benamou–Brenier formula and\r\nthe identification of absolutely continuous curves of measures.\r\nChapter 4 presents joint work with Lorenzo Portinale. We prove convergence of dynamical\r\ntransportation functionals on periodic graphs in the large-scale limit when the cost functional\r\nis asymptotically linear. Additionally, we show that discrete 1-Wasserstein distances converge\r\nto 1-Wasserstein distances constructed from crystalline norms on R\r\nd\r\n.\r\nChapter 5 concerns optimal empirical quantization: the problem of approximating a measure\r\nby the sum of n equally weighted Dirac deltas, so as to minimize the error in the p-Wasserstein\r\ndistance. Our main result is an analog of Zador’s theorem, providing asymptotic bounds for\r\nthe minimal error as n tends to infinity.\r\n"}],"author":[{"last_name":"Quattrocchi","orcid":"0009-0000-9773-1931","first_name":"Filippo","id":"3ebd6ba8-edfb-11eb-afb5-91a9745ba308","full_name":"Quattrocchi, Filippo"}],"degree_awarded":"PhD","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"file_name":"2025_quattrocchi_filippo_thesis.pdf","content_type":"application/pdf","date_updated":"2026-01-01T23:30:03Z","relation":"main_file","checksum":"6f55275bdf99992be3a6457d949dd664","file_id":"20653","access_level":"open_access","date_created":"2025-11-17T21:04:15Z","creator":"fquattro","embargo":"2026-01-01","file_size":4326411},{"content_type":"application/zip","file_name":"2025_quattrocchi_thesis.zip","file_id":"20654","relation":"source_file","checksum":"707e580f5d993a214c0dba456b75837b","date_updated":"2026-01-01T23:30:03Z","access_level":"closed","embargo_to":"open_access","file_size":11726509,"creator":"fquattro","date_created":"2025-11-17T21:05:43Z"}],"department":[{"_id":"GradSch"},{"_id":"JaMa"}],"publication_status":"published","date_updated":"2026-10-02T11:24:55Z","date_published":"2025-11-03T00:00:00Z","type":"dissertation","has_accepted_license":"1","language":[{"iso":"eng"}],"date_created":"2025-10-28T13:10:49Z","oa_version":"Published Version","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"240","citation":{"chicago":"Quattrocchi, Filippo. “Optimal Transport Methods for Kinetic Equations, Boundary Value Problems, and Discretization of Measures.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20563\">https://doi.org/10.15479/AT-ISTA-20563</a>.","ama":"Quattrocchi F. Optimal transport methods for kinetic equations, boundary value problems, and discretization of measures. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20563\">10.15479/AT-ISTA-20563</a>","ista":"Quattrocchi F. 2025. Optimal transport methods for kinetic equations, boundary value problems, and discretization of measures. Institute of Science and Technology Austria.","mla":"Quattrocchi, Filippo. <i>Optimal Transport Methods for Kinetic Equations, Boundary Value Problems, and Discretization of Measures</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20563\">10.15479/AT-ISTA-20563</a>.","apa":"Quattrocchi, F. (2025). <i>Optimal transport methods for kinetic equations, boundary value problems, and discretization of measures</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20563\">https://doi.org/10.15479/AT-ISTA-20563</a>","ieee":"F. Quattrocchi, “Optimal transport methods for kinetic equations, boundary value problems, and discretization of measures,” Institute of Science and Technology Austria, 2025.","short":"F. Quattrocchi, Optimal Transport Methods for Kinetic Equations, Boundary Value Problems, and Discretization of Measures, Institute of Science and Technology Austria, 2025."},"supervisor":[{"last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan","first_name":"Jan","orcid":"0000-0002-0845-1338"}],"project":[{"_id":"260482E2-B435-11E9-9278-68D0E5697425","grant_number":"F06504","name":"Taming Complexity in Partial Differential Systems","call_identifier":"FWF"}],"acknowledgement":"The research contained in this thesis has received funding from the Austrian Science\r\nFund (FWF) project 10.55776/F65."},{"abstract":[{"lang":"eng","text":"This is the first part of a general description in terms of mass transport for time-evolving interacting particles systems, at a mesoscopic level. Beyond kinetic theory, our framework naturally applies in biology, computer vision, and engineering. The central object of our study is a new discrepancy d between two probability distributions in position and velocity states, which is reminiscent of the 2-Wasserstein distance, but of second-order nature. We construct d in two steps. First, we optimise over transport plans. The cost function is given by the minimal acceleration between two coupled states on a fixed time horizon T. Second, we further optimise over the time horizon T > 0. We prove the existence of optimal transport plans and maps, and study two time-continuous characterisations of d. One is given in terms of dynamical transport plans. The other one -- in the spirit of the Benamou--Brenier formula -- is formulated as the minimisation of an action of the acceleration field, constrained by Vlasov's equations. Equivalence of static and dynamical formulations of d holds true. While part of this result can be derived from recent, parallel developments in optimal control between measures, we give an original proof relying on two new ingredients: Galilean regularisation of Vlasov's equations and a kinetic Monge--Mather shortening principle. Finally, we establish a first-order differential calculus in the geometry induced by d, and identify solutions to Vlasov's equations with curves of measures satisfying a certain d-absolute continuity condition. One consequence is an explicit formula for the d-derivative of such curves."}],"related_material":{"record":[{"relation":"dissertation_contains","id":"20563","status":"public"}]},"author":[{"id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1","full_name":"Brigati, Giovanni","first_name":"Giovanni","last_name":"Brigati"},{"orcid":"0000-0002-0845-1338","first_name":"Jan","full_name":"Maas, Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","last_name":"Maas"},{"first_name":"Filippo","orcid":"0009-0000-9773-1931","id":"3ebd6ba8-edfb-11eb-afb5-91a9745ba308","full_name":"Quattrocchi, Filippo","last_name":"Quattrocchi"}],"OA_type":"green","keyword":["optimal transport","kinetic theory","second-order discrepancy","Vlasov equation","Wasserstein splines."],"corr_author":"1","article_number":"2502.15665","publication":"arXiv","month":"08","_id":"20569","status":"public","year":"2025","article_processing_charge":"No","oa":1,"title":"Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between probability measures","fulldoi":"https://doi.org/10.48550/arXiv.2502.15665","doi":"10.48550/arXiv.2502.15665","OA_place":"repository","day":"10","acknowledgement":"This work was partially inspired by an unpublished note from 2014 by Guillaume Carlier,\r\nJean Dolbeault, and Bruno Nazaret. GB deeply thanks Jean Dolbeault for proposing\r\nthis problem to him, guiding him into the subject, and sharing the aforementioned note.\r\nWe are grateful to Karthik Elamvazhuthi for making us aware of the work [20].\r\nThe work of GB has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement\r\nNo 101034413.\r\nJM and FQ gratefully acknowledge support from the Austrian Science Fund (FWF)\r\nproject 10.55776/F65.","project":[{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504"},{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"}],"citation":{"chicago":"Brigati, Giovanni, Jan Maas, and Filippo Quattrocchi. “Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-Order Discrepancies between Probability Measures.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2502.15665\">https://doi.org/10.48550/arXiv.2502.15665</a>.","ieee":"G. Brigati, J. Maas, and F. Quattrocchi, “Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between probability measures,” <i>arXiv</i>. .","short":"G. Brigati, J. Maas, F. Quattrocchi, ArXiv (n.d.).","ista":"Brigati G, Maas J, Quattrocchi F. Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between probability measures. arXiv, 2502.15665.","ama":"Brigati G, Maas J, Quattrocchi F. Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between probability measures. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2502.15665\">10.48550/arXiv.2502.15665</a>","apa":"Brigati, G., Maas, J., &#38; Quattrocchi, F. (n.d.). Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between probability measures. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2502.15665\">https://doi.org/10.48550/arXiv.2502.15665</a>","mla":"Brigati, Giovanni, et al. “Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-Order Discrepancies between Probability Measures.” <i>ArXiv</i>, 2502.15665, doi:<a href=\"https://doi.org/10.48550/arXiv.2502.15665\">10.48550/arXiv.2502.15665</a>."},"external_id":{"arxiv":["2502.15665"]},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2502.15665","open_access":"1"}],"ec_funded":1,"type":"preprint","date_published":"2025-08-10T00:00:00Z","language":[{"iso":"eng"}],"oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-10-28T13:12:08Z","arxiv":1,"date_updated":"2026-10-07T22:31:31Z","department":[{"_id":"GradSch"},{"_id":"JaMa"}],"publication_status":"draft"},{"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"keyword":["Pten","mtor","cortical development","MADM","Mapk"],"corr_author":"1","abstract":[{"lang":"eng","text":"Cortical development has been studied for many decades and with each passing year, we learn \r\nmore about the processes that govern the tightly regulated developmental program. Up until \r\nrecently, the field has struggled to gain reliable access to progenitors at the single-cell level, \r\nlimiting the resolution at which we can study cortical development in vivo. Therefore, much of \r\nthe data we have on mammalian cortical development is at the cell population level. The \r\nsubsequent pages of this thesis describe novel elements of cortical development in mice; \r\nacquired using a candidate gene approach in conjunction with Mosaic Analysis with Double \r\nMarkers (MADM) to achieve single cell resolution. In this thesis, I briefly provide an overview \r\nof the state of the field, describe the methodology used to quantify morphological \r\ncharacteristics of neurons and glia, and delve into the role of Phosphatase and tensin \r\nhomologue on chromosome ten (Pten) in neurogenesis and gliogenesis in the developing mouse \r\ncortex. By using MADM to generate genetic mosaics, in which only a small fraction of cells \r\nare mutated, to study population-level changes, we can bypass the early postnatal lethality \r\nreported in Pten conditional knockouts (cKOs) using Emx1-Cre. We used Emx1-CreERT2 to \r\ninduce clonal deletion of Pten, and quantify RGP neurogenic output at the single progenitor \r\nlevel. Pten-mutant neuron populations within the mosaics were significantly expanded. In the \r\nlatter parts of this thesis, we describe how Pten deletion leads to an increase in the abundance \r\nof astrocytes. We availed ourselves of the flexibility offered by the MADM system to generate \r\nPten mosaics within a series of distinct knockout tissues to test for the interactions between \r\nPten and a battery of genes involved in distinct pro-gliogenic signaling pathways. Our survey \r\nof Pten’s interactions with genes in key signaling pathways reveals that ERK1/2 are the critical \r\neffectors downstream of EGFR signaling essential for gliogenesis. Altogether, our results \r\ndemonstrate that Pten plays critical and distinct roles throughout cortical RGP lineage \r\nprogression. "}],"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"17425"}]},"degree_awarded":"PhD","author":[{"last_name":"Miranda","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","full_name":"Miranda, Osvaldo","first_name":"Osvaldo","orcid":"0000-0001-6618-6889"}],"doi_confirm":"1","fulldoi":"https://doi.org/10.15479/AT-ISTA-20212","ddc":["570"],"publisher":"Institute of Science and Technology Austria","file_date_updated":"2026-08-26T22:30:02Z","doi":"10.15479/AT-ISTA-20212","OA_place":"publisher","publication_identifier":{"isbn":["978-3-99078-063-3"],"issn":["2663-337X"]},"day":"22","alternative_title":["ISTA Thesis"],"year":"2025","_id":"20212","month":"08","status":"public","oa":1,"article_processing_charge":"No","title":"Unraveling the role of Pten in cortical stem cell lineage progression using MADM","citation":{"ieee":"O. Miranda, “Unraveling the role of Pten in cortical stem cell lineage progression using MADM,” Institute of Science and Technology Austria, 2025.","short":"O. Miranda, Unraveling the Role of Pten in Cortical Stem Cell Lineage Progression Using MADM, Institute of Science and Technology Austria, 2025.","ama":"Miranda O. Unraveling the role of Pten in cortical stem cell lineage progression using MADM. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20212\">10.15479/AT-ISTA-20212</a>","ista":"Miranda O. 2025. Unraveling the role of Pten in cortical stem cell lineage progression using MADM. Institute of Science and Technology Austria.","apa":"Miranda, O. (2025). <i>Unraveling the role of Pten in cortical stem cell lineage progression using MADM</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20212\">https://doi.org/10.15479/AT-ISTA-20212</a>","mla":"Miranda, Osvaldo. <i>Unraveling the Role of Pten in Cortical Stem Cell Lineage Progression Using MADM</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20212\">10.15479/AT-ISTA-20212</a>.","chicago":"Miranda, Osvaldo. “Unraveling the Role of Pten in Cortical Stem Cell Lineage Progression Using MADM.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20212\">https://doi.org/10.15479/AT-ISTA-20212</a>."},"page":"119","supervisor":[{"last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","orcid":"0000-0003-2279-1061"}],"acknowledgement":"I would also like to\r\nthank the Austrian Academy of Sciences for awarding me a 2-year DOC fellowship\r\n(DOC26253).","project":[{"grant_number":"26253","name":"Molecular Mechanisms Regulating Cortical Neural Stem Cell Lineage Progression and Astrocyte Development","_id":"34c9fbcb-11ca-11ed-8bc3-98fa5658610d"}],"file":[{"date_updated":"2026-08-26T22:30:02Z","file_id":"20230","relation":"source_file","checksum":"3331f76bbef74ff4908e2d2c9262045c","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_name":"2025_MirandaRomero_OsvaldoAntonio_Thesis.docx","date_created":"2025-08-26T09:03:50Z","file_size":32887334,"creator":"omiranda","embargo_to":"open_access","access_level":"closed"},{"file_size":28636240,"creator":"omiranda","embargo":"2026-08-26","date_created":"2025-08-26T09:05:55Z","access_level":"open_access","file_id":"20231","relation":"main_file","checksum":"02509d50cff8e35c5bcbf71e8d658176","date_updated":"2026-08-26T22:30:02Z","content_type":"application/pdf","file_name":"2025_MirandaRomero_OsvaldoAntonio_Thesis.pdf"}],"date_updated":"2026-10-02T12:16:56Z","department":[{"_id":"GradSch"},{"_id":"SiHi"}],"publication_status":"published","has_accepted_license":"1","type":"dissertation","date_published":"2025-08-22T00:00:00Z","date_created":"2025-08-22T14:07:00Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa_version":"Published Version","language":[{"iso":"eng"}]},{"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","degree_awarded":"PhD","doi_confirm":"1","author":[{"last_name":"Wang","first_name":"Yiqun","full_name":"Wang, Yiqun","id":"82F537F2-B517-11E9-84D7-6433E6697425"}],"abstract":[{"lang":"eng","text":"Auxin is essential for many aspects of plant growth and development, from \r\nembryogenesis to organ senescence. Polar auxin transport leads to local auxin maxima and \r\ngradients, which are important for regulating various plant development process, including \r\nembryogenesis, organogenesis and vascular tissue formation. The polar auxin transport is \r\nmediated by auxin influx carrier AUX1/LAX proteins and efflux carrier PIN proteins. The \r\nregulation of PIN proteins is a key convergence of crosstalk between auxin and other \r\nhormones, such as cytokinin. Cytokinin promotes the degradation of PIN1 in Arabidopsis \r\nroots, preferentially the dephosphorylated PIN1, and the process is independent of \r\ntranscription and translation (Marhavý et al., 2011; Marhavý et al., 2014). The internalization \r\nof PIN proteins from plasma membrane is controlled by clathrin-mediated endocytosis \r\n(Dhonukshe et al., 2007; Kitakura et al., 2011). However, whether cytokinin affects the PIN1 \r\ndegradation through regulating the phosphorylation of PIN1 or trafficking components is \r\nunknown. Here, we demonstrate that dynamin related protein DRP2s are required for the \r\ncytokinin regulated trafficking of PIN1 and PIN2 in Arabidopsis root epidermal cells. Despite \r\nthe reported redundancy of DRP2A and DRP2B in gametophyte development, we found that \r\nCK-mediated PIN1 degradation and –induced PIN2 membrane localization is affected in drp2a \r\nor drp2b single mutants. Interestingly, we found that cytokinin regulates the recruitment of \r\nDRP2A—but not DRP2B—to clathrin-coated pits, and affects the stability and plasma \r\nmembrane localization of DRP2A. Furthermore, we studied the involvement of cytokinin \r\nreceptors in the regulation of cytokinin on DRP2A. Additionally, the assembly and disassembly \r\ncycle of dynamin is mediated by its dephosphorylation and phosphotylation cycle; thus, we \r\ninvestigated the role of DRP2A phosphorylation in its cytokinin-regulated assembly and in \r\ncytokinin-regulated PIN trafficking. Altogether, we found that cytokinin regulated PIN \r\ntrafficking in Arabidopsis root epidermal cells involves modulation of the phosphorylation of \r\nendocytosis accessory protein DRP2A. "}],"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"18063"}]},"publication_identifier":{"issn":["2663-337X"]},"day":"04","ddc":["580"],"fulldoi":"https://doi.org/10.15479/AT-ISTA-20117","publisher":"Institute of Science and Technology Austria","doi":"10.15479/AT-ISTA-20117","file_date_updated":"2026-09-03T22:30:03Z","OA_place":"publisher","oa":1,"article_processing_charge":"No","title":"The role of dynamin related protein 2A in cytokinin regulated plant growth and development","alternative_title":["ISTA Thesis"],"year":"2025","_id":"20117","month":"08","status":"public","page":"108","citation":{"chicago":"Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>.","mla":"Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>.","apa":"Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated plant growth and development</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>","ama":"Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>","ista":"Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. Institute of Science and Technology Austria.","short":"Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development, Institute of Science and Technology Austria, 2025.","ieee":"Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant growth and development,” Institute of Science and Technology Austria, 2025."},"acknowledgement":"I would also like to acknowledge the invaluable assistance provided by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility. The technical support and\r\nresources offered by these facilities were indispensable to the successful completion of my\r\nexperiments.","supervisor":[{"full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","orcid":"0000-0002-8510-9739","last_name":"Benková"}],"date_updated":"2026-10-02T12:33:36Z","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"publication_status":"published","file":[{"embargo_to":"open_access","access_level":"closed","date_created":"2025-08-22T08:22:10Z","creator":"yiqwang","file_size":25798848,"file_name":"2025_Wang_Yiqun_Thesis.docx","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_updated":"2026-09-03T22:30:03Z","checksum":"36b87c17d12c7bf5955d6d812acb8d77","relation":"source_file","file_id":"20209"},{"access_level":"open_access","embargo":"2026-09-03","creator":"yiqwang","file_size":12628313,"date_created":"2025-08-22T10:32:30Z","file_name":"2025_Wang_Yiqun_Thesis.pdf","content_type":"application/pdf","checksum":"8d7a2383f66377da675d379ec30ea0fe","relation":"main_file","file_id":"20211","date_updated":"2026-09-03T22:30:03Z"}],"date_created":"2025-08-04T15:24:21Z","oa_version":"Published Version","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","language":[{"iso":"eng"}],"has_accepted_license":"1","type":"dissertation","date_published":"2025-08-04T00:00:00Z"},{"extern":"1","publication_status":"published","date_updated":"2026-06-22T10:32:25Z","article_type":"original","quality_controlled":"1","intvolume":"       173","arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-06-19T07:34:05Z","oa_version":"Preprint","language":[{"iso":"eng"}],"date_published":"2024-05-15T00:00:00Z","type":"journal_article","issue":"7","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2209.07501"}],"external_id":{"arxiv":["2209.07501"]},"citation":{"short":"A. Chapouto, R. Killip, M. Vişan, Duke Mathematical Journal 173 (2024) 1227–1267.","ieee":"A. Chapouto, R. Killip, and M. Vişan, “Bounded solutions of KdV: Uniqueness and the loss of almost periodicity,” <i>Duke Mathematical Journal</i>, vol. 173, no. 7. Duke University Press, pp. 1227–1267, 2024.","mla":"Chapouto, Andreia, et al. “Bounded Solutions of KdV: Uniqueness and the Loss of Almost Periodicity.” <i>Duke Mathematical Journal</i>, vol. 173, no. 7, Duke University Press, 2024, pp. 1227–67, doi:<a href=\"https://doi.org/10.1215/00127094-2023-0035\">10.1215/00127094-2023-0035</a>.","apa":"Chapouto, A., Killip, R., &#38; Vişan, M. (2024). Bounded solutions of KdV: Uniqueness and the loss of almost periodicity. <i>Duke Mathematical Journal</i>. Duke University Press. <a href=\"https://doi.org/10.1215/00127094-2023-0035\">https://doi.org/10.1215/00127094-2023-0035</a>","ama":"Chapouto A, Killip R, Vişan M. Bounded solutions of KdV: Uniqueness and the loss of almost periodicity. <i>Duke Mathematical Journal</i>. 2024;173(7):1227-1267. doi:<a href=\"https://doi.org/10.1215/00127094-2023-0035\">10.1215/00127094-2023-0035</a>","ista":"Chapouto A, Killip R, Vişan M. 2024. Bounded solutions of KdV: Uniqueness and the loss of almost periodicity. Duke Mathematical Journal. 173(7), 1227–1267.","chicago":"Chapouto, Andreia, Rowan Killip, and Monica Vişan. “Bounded Solutions of KdV: Uniqueness and the Loss of Almost Periodicity.” <i>Duke Mathematical Journal</i>. Duke University Press, 2024. <a href=\"https://doi.org/10.1215/00127094-2023-0035\">https://doi.org/10.1215/00127094-2023-0035</a>."},"page":"1227-1267","volume":173,"day":"15","publication_identifier":{"issn":["0012-7094"]},"publisher":"Duke University Press","doi":"10.1215/00127094-2023-0035","OA_place":"repository","fulldoi":"https://doi.org/10.1215/00127094-2023-0035","title":"Bounded solutions of KdV: Uniqueness and the loss of almost periodicity","scopus_import":"1","oa":1,"article_processing_charge":"No","year":"2024","status":"public","_id":"22026","month":"05","publication":"Duke Mathematical Journal","das_tickbox":"1","OA_type":"green","keyword":["Almost-periodic solutions","Korteweg–de Vries","unconditional uniqueness"],"author":[{"last_name":"Chapouto","first_name":"Andreia","full_name":"Chapouto, Andreia"},{"first_name":"Rowan","full_name":"Killip, Rowan","last_name":"Killip"},{"id":"056daca0-b8d1-11f0-964f-f91054abf8ca","full_name":"Visan, Monica","first_name":"Monica","last_name":"Visan"}],"abstract":[{"text":"We address two pressing questions in the theory of the Korteweg–de Vries (KdV) equation. First, we show the uniqueness of solutions to KdV that are merely bounded, without any further decay, regularity, periodicity, or almost periodicity assumptions. The second question, emphasized by Deift, regards whether almost periodic initial data leads to almost periodic solutions to KdV. Building on the new observation that this is false for the Airy equation, we construct an example of almost periodic initial data whose KdV evolution remains bounded, but fails to be almost periodic at a later time. Our uniqueness result ensures that the solution constructed is the unique development of this initial data.","lang":"eng"}]},{"fulldoi":"https://doi.org/10.1007/s40072-022-00277-3","ddc":["510"],"doi":"10.1007/s40072-022-00277-3","file_date_updated":"2024-07-22T09:29:48Z","publisher":"Springer Nature","publication_identifier":{"eissn":["2194-041X"],"issn":["2194-0401"]},"day":"01","publication":"Stochastics and Partial Differential Equations: Analysis and Computations","_id":"12178","status":"public","month":"03","year":"2024","article_processing_charge":"Yes (via OA deal)","oa":1,"scopus_import":"1","title":"The stochastic primitive equations with transport noise and turbulent pressure","keyword":["Applied Mathematics","Modeling and Simulation","Statistics and Probability"],"isi":1,"abstract":[{"lang":"eng","text":"In this paper we consider the stochastic primitive equation for geophysical flows subject to transport noise and turbulent pressure. Admitting very rough noise terms, the global existence and uniqueness of solutions to this stochastic partial differential equation are proven using stochastic maximal L² regularity, the theory of critical spaces for stochastic evolution equations, and global a priori bounds. Compared to other results in this direction, we do not need any smallness assumption on the transport noise which acts directly on the velocity field and we also allow rougher noise terms. The adaptation to Stratonovich type noise and, more generally, to variable viscosity and/or conductivity are discussed as well."}],"author":[{"first_name":"Antonio","orcid":"0000-0002-9573-2962","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72","full_name":"Agresti, Antonio","last_name":"Agresti"},{"full_name":"Hieber, Matthias","first_name":"Matthias","last_name":"Hieber"},{"full_name":"Hussein, Amru","first_name":"Amru","last_name":"Hussein"},{"last_name":"Saal","full_name":"Saal, Martin","first_name":"Martin"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"date_updated":"2024-07-22T09:29:48Z","file_id":"17297","checksum":"59c9000761134d681bdf9d482664044c","relation":"main_file","content_type":"application/pdf","file_name":"2024_StochasticsEquations_Agresti.pdf","success":1,"date_created":"2024-07-22T09:29:48Z","file_size":1206413,"creator":"dernst","access_level":"open_access"}],"article_type":"original","date_updated":"2024-07-22T09:30:40Z","department":[{"_id":"JuFi"}],"publication_status":"published","type":"journal_article","has_accepted_license":"1","date_published":"2024-03-01T00:00:00Z","language":[{"iso":"eng"}],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-01-12T12:12:29Z","quality_controlled":"1","arxiv":1,"intvolume":"        12","page":"53-133","citation":{"chicago":"Agresti, Antonio, Matthias Hieber, Amru Hussein, and Martin Saal. “The Stochastic Primitive Equations with Transport Noise and Turbulent Pressure.” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s40072-022-00277-3\">https://doi.org/10.1007/s40072-022-00277-3</a>.","ieee":"A. Agresti, M. Hieber, A. Hussein, and M. Saal, “The stochastic primitive equations with transport noise and turbulent pressure,” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>, vol. 12. Springer Nature, pp. 53–133, 2024.","short":"A. Agresti, M. Hieber, A. Hussein, M. Saal, Stochastics and Partial Differential Equations: Analysis and Computations 12 (2024) 53–133.","ista":"Agresti A, Hieber M, Hussein A, Saal M. 2024. The stochastic primitive equations with transport noise and turbulent pressure. Stochastics and Partial Differential Equations: Analysis and Computations. 12, 53–133.","ama":"Agresti A, Hieber M, Hussein A, Saal M. The stochastic primitive equations with transport noise and turbulent pressure. <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. 2024;12:53-133. doi:<a href=\"https://doi.org/10.1007/s40072-022-00277-3\">10.1007/s40072-022-00277-3</a>","apa":"Agresti, A., Hieber, M., Hussein, A., &#38; Saal, M. (2024). The stochastic primitive equations with transport noise and turbulent pressure. <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s40072-022-00277-3\">https://doi.org/10.1007/s40072-022-00277-3</a>","mla":"Agresti, Antonio, et al. “The Stochastic Primitive Equations with Transport Noise and Turbulent Pressure.” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>, vol. 12, Springer Nature, 2024, pp. 53–133, doi:<a href=\"https://doi.org/10.1007/s40072-022-00277-3\">10.1007/s40072-022-00277-3</a>."},"external_id":{"arxiv":["2109.09561"],"isi":["000874389000001"]},"acknowledgement":"The authors thank the anonymous referees for their helpful comments and suggestions. Open Access funding enabled and organized by Projekt DEAL.","volume":12},{"oa":1,"article_processing_charge":"Yes (in subscription journal)","title":"The critical variational setting for stochastic evolution equations","scopus_import":"1","publication":"Probability Theory and Related Fields","year":"2024","status":"public","_id":"12485","month":"04","publication_identifier":{"issn":["0178-8051"],"eissn":["1432-2064"]},"day":"01","fulldoi":"https://doi.org/10.1007/s00440-023-01249-x","ddc":["510"],"publisher":"Springer Nature","doi":"10.1007/s00440-023-01249-x","file_date_updated":"2024-07-22T09:21:09Z","author":[{"full_name":"Agresti, Antonio","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72","orcid":"0000-0002-9573-2962","first_name":"Antonio","last_name":"Agresti"},{"last_name":"Veraar","first_name":"Mark","full_name":"Veraar, Mark"}],"abstract":[{"text":"In this paper we introduce the critical variational setting for parabolic stochastic evolution equations of quasi- or semi-linear type. Our results improve many of the abstract results in the classical variational setting. In particular, we are able to replace the usual weak or local monotonicity condition by a more flexible local Lipschitz condition. Moreover, the usual growth conditions on the multiplicative noise are weakened considerably. Our new setting provides general conditions under which local and global existence and uniqueness hold. Moreover, we prove continuous dependence on the initial data. We show that many classical SPDEs, which could not be covered by the classical variational setting, do fit in the critical variational setting. In particular, this is the case for the Cahn-Hilliard equations, tamed Navier-Stokes equations, and Allen-Cahn equation.","lang":"eng"}],"isi":1,"oa_version":"Published Version","date_created":"2023-02-02T10:45:15Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","language":[{"iso":"eng"}],"quality_controlled":"1","intvolume":"       188","arxiv":1,"has_accepted_license":"1","type":"journal_article","date_published":"2024-04-01T00:00:00Z","date_updated":"2025-09-04T11:27:46Z","publication_status":"published","department":[{"_id":"JuFi"}],"file":[{"file_size":942801,"creator":"dernst","date_created":"2024-07-22T09:21:09Z","access_level":"open_access","file_id":"17296","checksum":"b8572339dbc5b8de4934dc5fd34afc7d","relation":"main_file","date_updated":"2024-07-22T09:21:09Z","success":1,"content_type":"application/pdf","file_name":"2024_ProbTheory_Agresti.pdf"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","acknowledgement":"The first author has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 948819) . The second author is supported by the VICI subsidy VI.C.212.027 of the Netherlands Organisation for Scientific Research (NWO).","volume":188,"project":[{"call_identifier":"H2020","_id":"0aa76401-070f-11eb-9043-b5bb049fa26d","grant_number":"948819","name":"Bridging Scales in Random Materials"}],"ec_funded":1,"external_id":{"arxiv":["2206.00230"],"isi":["001154226500001"]},"citation":{"chicago":"Agresti, Antonio, and Mark Veraar. “The Critical Variational Setting for Stochastic Evolution Equations.” <i>Probability Theory and Related Fields</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00440-023-01249-x\">https://doi.org/10.1007/s00440-023-01249-x</a>.","ama":"Agresti A, Veraar M. The critical variational setting for stochastic evolution equations. <i>Probability Theory and Related Fields</i>. 2024;188:957-1015. doi:<a href=\"https://doi.org/10.1007/s00440-023-01249-x\">10.1007/s00440-023-01249-x</a>","ista":"Agresti A, Veraar M. 2024. The critical variational setting for stochastic evolution equations. Probability Theory and Related Fields. 188, 957–1015.","mla":"Agresti, Antonio, and Mark Veraar. “The Critical Variational Setting for Stochastic Evolution Equations.” <i>Probability Theory and Related Fields</i>, vol. 188, Springer Nature, 2024, pp. 957–1015, doi:<a href=\"https://doi.org/10.1007/s00440-023-01249-x\">10.1007/s00440-023-01249-x</a>.","apa":"Agresti, A., &#38; Veraar, M. (2024). The critical variational setting for stochastic evolution equations. <i>Probability Theory and Related Fields</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00440-023-01249-x\">https://doi.org/10.1007/s00440-023-01249-x</a>","ieee":"A. Agresti and M. Veraar, “The critical variational setting for stochastic evolution equations,” <i>Probability Theory and Related Fields</i>, vol. 188. Springer Nature, pp. 957–1015, 2024.","short":"A. Agresti, M. Veraar, Probability Theory and Related Fields 188 (2024) 957–1015."},"page":"957-1015"},{"publication":"Stochastics and Partial Differential Equations: Analysis and Computations","year":"2024","month":"09","_id":"12486","status":"public","oa":1,"article_processing_charge":"No","title":"Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations","scopus_import":"1","ddc":["510"],"fulldoi":"https://doi.org/10.1007/s40072-023-00319-4","publisher":"Springer Nature","doi":"10.1007/s40072-023-00319-4","file_date_updated":"2025-01-09T08:01:02Z","OA_place":"publisher","publication_identifier":{"eissn":["2194-041X"],"issn":["2194-0401"]},"day":"01","abstract":[{"text":"This paper is concerned with the problem of regularization by noise of systems of reaction–diffusion equations with mass control. It is known that strong solutions to such systems of PDEs may blow-up in finite time. Moreover, for many systems of practical interest, establishing whether the blow-up occurs or not is an open question. Here we prove that a suitable multiplicative noise of transport type has a regularizing effect. More precisely, for both a sufficiently noise intensity and a high spectrum, the blow-up of strong solutions is delayed up to an arbitrary large time. Global existence is shown for the case of exponentially decreasing mass. The proofs combine and extend recent developments in regularization by noise and in the Lp(Lq)-approach to stochastic PDEs, highlighting new connections between the two areas.","lang":"eng"}],"pmid":1,"author":[{"orcid":"0000-0002-9573-2962","first_name":"Antonio","full_name":"Agresti, Antonio","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72","last_name":"Agresti"}],"OA_type":"hybrid","corr_author":"1","isi":1,"has_accepted_license":"1","type":"journal_article","date_published":"2024-09-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-02-02T10:45:47Z","oa_version":"Published Version","language":[{"iso":"eng"}],"intvolume":"        12","arxiv":1,"quality_controlled":"1","file":[{"creator":"dernst","file_size":1320682,"date_created":"2025-01-09T08:01:02Z","access_level":"open_access","checksum":"3c93d07a5f7e0b0caa8062eadcfa69c2","relation":"main_file","file_id":"18787","date_updated":"2025-01-09T08:01:02Z","success":1,"file_name":"2024_StochPartDiffEquations_Agresti.pdf","content_type":"application/pdf"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","date_updated":"2025-08-05T13:23:09Z","department":[{"_id":"JuFi"}],"publication_status":"published","acknowledgement":"The author has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 948819).\r\nThe author thanks Lorenzo Dello Schiavo, Lucio Galeati and Mark Veraar for helpful comments. The author acknowledges Caterina Balzotti for her support in creating the picture. The author\r\nthanks the anonymous referee for helpful comments. ","volume":12,"project":[{"_id":"0aa76401-070f-11eb-9043-b5bb049fa26d","grant_number":"948819","name":"Bridging Scales in Random Materials","call_identifier":"H2020"}],"external_id":{"pmid":["39104877"],"arxiv":["2207.08293"],"isi":["001108594600001"]},"page":"1907-1981","citation":{"apa":"Agresti, A. (2024). Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations. <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s40072-023-00319-4\">https://doi.org/10.1007/s40072-023-00319-4</a>","mla":"Agresti, Antonio. “Delayed Blow-up and Enhanced Diffusion by Transport Noise for Systems of Reaction-Diffusion Equations.” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>, vol. 12, Springer Nature, 2024, pp. 1907–81, doi:<a href=\"https://doi.org/10.1007/s40072-023-00319-4\">10.1007/s40072-023-00319-4</a>.","ista":"Agresti A. 2024. Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations. Stochastics and Partial Differential Equations: Analysis and Computations. 12, 1907–1981.","ama":"Agresti A. Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations. <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. 2024;12:1907-1981. doi:<a href=\"https://doi.org/10.1007/s40072-023-00319-4\">10.1007/s40072-023-00319-4</a>","short":"A. Agresti, Stochastics and Partial Differential Equations: Analysis and Computations 12 (2024) 1907–1981.","ieee":"A. Agresti, “Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion equations,” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>, vol. 12. Springer Nature, pp. 1907–1981, 2024.","chicago":"Agresti, Antonio. “Delayed Blow-up and Enhanced Diffusion by Transport Noise for Systems of Reaction-Diffusion Equations.” <i>Stochastics and Partial Differential Equations: Analysis and Computations</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s40072-023-00319-4\">https://doi.org/10.1007/s40072-023-00319-4</a>."},"ec_funded":1},{"acknowledgement":"Tobias Winkler and Joost-Pieter Katoen are supported by the DFG RTG 2236 UnRAVeL and the innovation programme under the Marie Skłodowska-Curie grant agreement No. 101008233 (Mission). Krishnendu Chatterjee is supported by the ERC CoG 863818 (ForM-SMArt) and the Vienna Science and Technology Fund (WWTF) Project ICT15-003. Maximilian Weininger is supported by the DFG projects 383882557 Statistical Unbounded Verification (SUV) and 427755713 Group-By Objectives in Probabilistic Verification (GOPro). Stefanie Mohr is supported by the DFG RTG 2428 CONVEY. Open Access funding enabled and organized by Projekt DEAL.","volume":63,"project":[{"call_identifier":"H2020","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"},{"_id":"25892FC0-B435-11E9-9278-68D0E5697425","name":"Efficient Algorithms for Computer Aided Verification","grant_number":"ICT15-003"}],"external_id":{"isi":["000946174300001"]},"citation":{"apa":"Chatterjee, K., Katoen, J. P., Mohr, S., Weininger, M., &#38; Winkler, T. (2024). Stochastic games with lexicographic objectives. <i>Formal Methods in System Design</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10703-023-00411-4\">https://doi.org/10.1007/s10703-023-00411-4</a>","mla":"Chatterjee, Krishnendu, et al. “Stochastic Games with Lexicographic Objectives.” <i>Formal Methods in System Design</i>, vol. 63, Springer Nature, 2024, pp. 40–80, doi:<a href=\"https://doi.org/10.1007/s10703-023-00411-4\">10.1007/s10703-023-00411-4</a>.","ista":"Chatterjee K, Katoen JP, Mohr S, Weininger M, Winkler T. 2024. Stochastic games with lexicographic objectives. Formal Methods in System Design. 63, 40–80.","ama":"Chatterjee K, Katoen JP, Mohr S, Weininger M, Winkler T. Stochastic games with lexicographic objectives. <i>Formal Methods in System Design</i>. 2024;63:40-80. doi:<a href=\"https://doi.org/10.1007/s10703-023-00411-4\">10.1007/s10703-023-00411-4</a>","short":"K. Chatterjee, J.P. Katoen, S. Mohr, M. Weininger, T. Winkler, Formal Methods in System Design 63 (2024) 40–80.","ieee":"K. Chatterjee, J. P. Katoen, S. Mohr, M. Weininger, and T. Winkler, “Stochastic games with lexicographic objectives,” <i>Formal Methods in System Design</i>, vol. 63. Springer Nature, pp. 40–80, 2024.","chicago":"Chatterjee, Krishnendu, Joost P Katoen, Stefanie Mohr, Maximilian Weininger, and Tobias Winkler. “Stochastic Games with Lexicographic Objectives.” <i>Formal Methods in System Design</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s10703-023-00411-4\">https://doi.org/10.1007/s10703-023-00411-4</a>."},"page":"40-80","ec_funded":1,"has_accepted_license":"1","type":"journal_article","date_published":"2024-10-01T00:00:00Z","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-03-19T23:00:59Z","language":[{"iso":"eng"}],"intvolume":"        63","quality_controlled":"1","file":[{"success":1,"file_name":"2024_FromMethodsSys_Chatterjee.pdf","content_type":"application/pdf","relation":"main_file","checksum":"111e76b76163640a2c89237642af586f","file_id":"18781","date_updated":"2025-01-09T07:31:31Z","access_level":"open_access","creator":"dernst","file_size":2614190,"date_created":"2025-01-09T07:31:31Z"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","date_updated":"2026-04-16T09:31:13Z","publication_status":"published","department":[{"_id":"KrCh"}],"abstract":[{"lang":"eng","text":"We study turn-based stochastic zero-sum games with lexicographic preferences over objectives. Stochastic games are standard models in control, verification, and synthesis of stochastic reactive systems that exhibit both randomness as well as controllable and adversarial non-determinism. Lexicographic order allows one to consider multiple objectives with a strict preference order. To the best of our knowledge, stochastic games with lexicographic objectives have not been studied before. For a mixture of reachability and safety objectives, we show that deterministic lexicographically optimal strategies exist and memory is only required to remember the already satisfied and violated objectives. For a constant number of objectives, we show that the relevant decision problem is in NP∩coNP, matching the current known bound for single objectives; and in general the decision problem is PSPACE-hard and can be solved in NEXPTIME∩coNEXPTIME. We present an algorithm that computes the lexicographically optimal strategies via a reduction to the computation of optimal strategies in a sequence of single-objectives games. For omega-regular objectives, we restrict our analysis to one-player games, also known as Markov decision processes. We show that lexicographically optimal strategies exist and need either randomization or finite memory. We present an algorithm that solves the relevant decision problem in polynomial time. We have implemented our algorithms and report experimental results on various case studies."}],"related_material":{"record":[{"id":"8272","relation":"earlier_version","status":"public"}]},"author":[{"last_name":"Chatterjee","full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","first_name":"Krishnendu"},{"last_name":"Katoen","orcid":"0000-0002-6143-1926","first_name":"Joost P","id":"4524F760-F248-11E8-B48F-1D18A9856A87","full_name":"Katoen, Joost P"},{"last_name":"Mohr","full_name":"Mohr, Stefanie","first_name":"Stefanie"},{"full_name":"Weininger, Maximilian","first_name":"Maximilian","last_name":"Weininger"},{"last_name":"Winkler","full_name":"Winkler, Tobias","first_name":"Tobias"}],"OA_type":"hybrid","isi":1,"publication":"Formal Methods in System Design","year":"2024","status":"public","_id":"12738","month":"10","oa":1,"article_processing_charge":"Yes (via OA deal)","title":"Stochastic games with lexicographic objectives","scopus_import":"1","fulldoi":"https://doi.org/10.1007/s10703-023-00411-4","ddc":["000"],"publisher":"Springer Nature","doi":"10.1007/s10703-023-00411-4","OA_place":"publisher","file_date_updated":"2025-01-09T07:31:31Z","publication_identifier":{"eissn":["1572-8102"]},"day":"01"},{"page":"230-246.e11","citation":{"chicago":"Cheung, Giselle T, Florian Pauler, Peter Koppensteiner, Thomas Krausgruber, Carmen Streicher, Martin Schrammel, Natalie Y Özgen, et al. “Multipotent Progenitors Instruct Ontogeny of the Superior Colliculus.” <i>Neuron</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.neuron.2023.11.009\">https://doi.org/10.1016/j.neuron.2023.11.009</a>.","short":"G.T. Cheung, F. Pauler, P. Koppensteiner, T. Krausgruber, C. Streicher, M. Schrammel, N.Y. Özgen, A. Ivec, C. Bock, R. Shigemoto, S. Hippenmeyer, Neuron 112 (2024) 230–246.e11.","ieee":"G. T. Cheung <i>et al.</i>, “Multipotent progenitors instruct ontogeny of the superior colliculus,” <i>Neuron</i>, vol. 112, no. 2. Elsevier, p. 230–246.e11, 2024.","mla":"Cheung, Giselle T., et al. “Multipotent Progenitors Instruct Ontogeny of the Superior Colliculus.” <i>Neuron</i>, vol. 112, no. 2, Elsevier, 2024, p. 230–246.e11, doi:<a href=\"https://doi.org/10.1016/j.neuron.2023.11.009\">10.1016/j.neuron.2023.11.009</a>.","apa":"Cheung, G. T., Pauler, F., Koppensteiner, P., Krausgruber, T., Streicher, C., Schrammel, M., … Hippenmeyer, S. (2024). Multipotent progenitors instruct ontogeny of the superior colliculus. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2023.11.009\">https://doi.org/10.1016/j.neuron.2023.11.009</a>","ama":"Cheung GT, Pauler F, Koppensteiner P, et al. Multipotent progenitors instruct ontogeny of the superior colliculus. <i>Neuron</i>. 2024;112(2):230-246.e11. doi:<a href=\"https://doi.org/10.1016/j.neuron.2023.11.009\">10.1016/j.neuron.2023.11.009</a>","ista":"Cheung GT, Pauler F, Koppensteiner P, Krausgruber T, Streicher C, Schrammel M, Özgen NY, Ivec A, Bock C, Shigemoto R, Hippenmeyer S. 2024. Multipotent progenitors instruct ontogeny of the superior colliculus. Neuron. 112(2), 230–246.e11."},"external_id":{"isi":["001163937900001"],"pmid":["38096816"]},"issue":"2","volume":112,"acknowledgement":"We thank Liqun Luo for his continued support, for providing essential resources for generating Fzd10-CreER mice which were generated in his laboratory, and for comments on the manuscript; W. Zhong for providing Nestin-Cre transgenic mouse line for this study; A. Heger for mouse colony management; R. Beattie and T. Asenov for designing and producing components of acute slice recovery chamber for MADM-CloneSeq experiments; and K. Leopold, J. Rodarte and N. Amberg for initial experiments, technical support and/or assistance. This study was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by the Imaging & Optics Facility (IOF), Laboratory Support Facility (LSF), Miba Machine Shop, and Pre-clinical Facility (PCF). G.C. received funding from European Commission (IST plus postdoctoral fellowship). This work was supported by ISTA institutional\r\nfunds; the Austrian Science Fund Special Research Programmes (FWF SFB F78 Neuro Stem Modulation) to S.H. ","project":[{"name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F7805","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"access_level":"open_access","date_created":"2024-02-06T13:56:15Z","file_size":5942467,"creator":"dernst","content_type":"application/pdf","file_name":"2024_Neuron_Cheung.pdf","success":1,"date_updated":"2024-02-06T13:56:15Z","file_id":"14944","relation":"main_file","checksum":"32b3788f7085cf44a84108d8faaff3ce"}],"article_type":"original","date_updated":"2025-12-30T10:54:12Z","publication_status":"published","department":[{"_id":"SiHi"},{"_id":"RySh"}],"type":"journal_article","has_accepted_license":"1","date_published":"2024-01-17T00:00:00Z","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-04-27T09:41:48Z","oa_version":"Published Version","quality_controlled":"1","intvolume":"       112","acknowledged_ssus":[{"_id":"Bio"},{"_id":"M-Shop"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","isi":1,"abstract":[{"lang":"eng","text":"The superior colliculus (SC) in the mammalian midbrain is essential for multisensory integration and is composed of a rich diversity of excitatory and inhibitory neurons and glia. However, the developmental principles directing the generation of SC cell-type diversity are not understood. Here, we pursued systematic cell lineage tracing in silico and in vivo, preserving full spatial information, using genetic mosaic analysis with double markers (MADM)-based clonal analysis with single-cell sequencing (MADM-CloneSeq). The analysis of clonally related cell lineages revealed that radial glial progenitors (RGPs) in SC are exceptionally multipotent. Individual resident RGPs have the capacity to produce all excitatory and inhibitory SC neuron types, even at the stage of terminal division. While individual clonal units show no pre-defined cellular composition, the establishment of appropriate relative proportions of distinct neuronal types occurs in a PTEN-dependent manner. Collectively, our findings provide an inaugural framework at the single-RGP/-cell level of the mammalian SC ontogeny."}],"related_material":{"link":[{"url":"https://ista.ac.at/en/news/the-pedigree-of-brain-cells/","relation":"press_release","description":"News on ISTA Website"}]},"pmid":1,"author":[{"orcid":"0000-0001-8457-2572","first_name":"Giselle T","id":"471195F6-F248-11E8-B48F-1D18A9856A87","full_name":"Cheung, Giselle T","last_name":"Cheung"},{"last_name":"Pauler","first_name":"Florian","orcid":"0000-0002-7462-0048","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian"},{"first_name":"Peter","orcid":"0000-0002-3509-1948","id":"3B8B25A8-F248-11E8-B48F-1D18A9856A87","full_name":"Koppensteiner, Peter","last_name":"Koppensteiner"},{"full_name":"Krausgruber, Thomas","first_name":"Thomas","last_name":"Krausgruber"},{"first_name":"Carmen","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher"},{"first_name":"Martin","full_name":"Schrammel, Martin","id":"f13e7cae-e8bd-11ed-841a-96dedf69f46d","last_name":"Schrammel"},{"full_name":"Özgen, Natalie Y","id":"e68ece33-f6e0-11ea-865d-ae1031dcc090","first_name":"Natalie Y","last_name":"Özgen"},{"last_name":"Ivec","id":"1d144691-e8be-11ed-9b33-bdd3077fad4c","full_name":"Ivec, Alexis","first_name":"Alexis"},{"first_name":"Christoph","full_name":"Bock, Christoph","last_name":"Bock"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","first_name":"Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto"},{"last_name":"Hippenmeyer","first_name":"Simon","orcid":"0000-0003-2279-1061","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87"}],"ddc":["570"],"fulldoi":"https://doi.org/10.1016/j.neuron.2023.11.009","file_date_updated":"2024-02-06T13:56:15Z","doi":"10.1016/j.neuron.2023.11.009","publisher":"Elsevier","publication_identifier":{"issn":["0896-6273"]},"day":"17","publication":"Neuron","status":"public","_id":"12875","month":"01","year":"2024","article_processing_charge":"Yes (via OA deal)","oa":1,"scopus_import":"1","title":"Multipotent progenitors instruct ontogeny of the superior colliculus"},{"isi":1,"abstract":[{"lang":"eng","text":"The direct, solid state, and reversible conversion between heat and electricity using thermoelectric devices finds numerous potential uses, especially around room temperature. However, the relatively high material processing cost limits their real applications. Silver selenide (Ag2Se) is one of the very few n-type thermoelectric (TE) materials for room-temperature applications. Herein, we report a room temperature, fast, and aqueous-phase synthesis approach to produce Ag2Se, which can be extended to other metal chalcogenides. These materials reach TE figures of merit (zT) of up to 0.76 at 380 K. To improve these values, bismuth sulfide (Bi2S3) particles also prepared in an aqueous solution are incorporated into the Ag2Se matrix. In this way, a series of Ag2Se/Bi2S3 composites with Bi2S3 wt % of 0.5, 1.0, and 1.5 are prepared by solution blending and hot-press sintering. The presence of Bi2S3 significantly improves the Seebeck coefficient and power factor while at the same time decreasing the thermal conductivity with no apparent drop in electrical conductivity. Thus, a maximum zT value of 0.96 is achieved in the composites with 1.0 wt % Bi2S3 at 370 K. Furthermore, a high average zT value (zTave) of 0.93 in the 300–390 K range is demonstrated."}],"author":[{"last_name":"Nan","full_name":"Nan, Bingfei","first_name":"Bingfei"},{"last_name":"Li","full_name":"Li, Mengyao","first_name":"Mengyao"},{"last_name":"Zhang","first_name":"Yu","full_name":"Zhang, Yu"},{"first_name":"Ke","full_name":"Xiao, Ke","last_name":"Xiao"},{"full_name":"Lim, Khak Ho","first_name":"Khak Ho","last_name":"Lim"},{"last_name":"Chang","orcid":"0000-0002-9515-4277","first_name":"Cheng","id":"9E331C2E-9F27-11E9-AE48-5033E6697425","full_name":"Chang, Cheng"},{"last_name":"Han","first_name":"Xu","full_name":"Han, Xu"},{"full_name":"Zuo, Yong","first_name":"Yong","last_name":"Zuo"},{"first_name":"Junshan","full_name":"Li, Junshan","last_name":"Li"},{"last_name":"Arbiol","first_name":"Jordi","full_name":"Arbiol, Jordi"},{"full_name":"Llorca, Jordi","first_name":"Jordi","last_name":"Llorca"},{"first_name":"Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","last_name":"Ibáñez"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"}],"pmid":1,"publisher":"American Chemical Society","doi":"10.1021/acsaelm.3c00055","file_date_updated":"2024-07-16T07:54:21Z","fulldoi":"https://doi.org/10.1021/acsaelm.3c00055","ddc":["540"],"day":"28","publication_identifier":{"eissn":["2637-6113"]},"year":"2024","_id":"13093","status":"public","month":"05","publication":"ACS Applied Electronic Materials","title":"Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature","scopus_import":"1","oa":1,"article_processing_charge":"Yes (in subscription journal)","external_id":{"pmid":["38828037"],"isi":["000986859000001"]},"citation":{"chicago":"Nan, Bingfei, Mengyao Li, Yu Zhang, Ke Xiao, Khak Ho Lim, Cheng Chang, Xu Han, et al. “Engineering of Thermoelectric Composites Based on Silver Selenide in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic Materials</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/acsaelm.3c00055\">https://doi.org/10.1021/acsaelm.3c00055</a>.","apa":"Nan, B., Li, M., Zhang, Y., Xiao, K., Lim, K. H., Chang, C., … Cabot, A. (2024). Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. <i>ACS Applied Electronic Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaelm.3c00055\">https://doi.org/10.1021/acsaelm.3c00055</a>","mla":"Nan, Bingfei, et al. “Engineering of Thermoelectric Composites Based on Silver Selenide in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic Materials</i>, vol. 6, no. 5, American Chemical Society, 2024, pp. 2807–215, doi:<a href=\"https://doi.org/10.1021/acsaelm.3c00055\">10.1021/acsaelm.3c00055</a>.","ista":"Nan B, Li M, Zhang Y, Xiao K, Lim KH, Chang C, Han X, Zuo Y, Li J, Arbiol J, Llorca J, Ibáñez M, Cabot A. 2024. Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. ACS Applied Electronic Materials. 6(5), 2807–215.","ama":"Nan B, Li M, Zhang Y, et al. Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. <i>ACS Applied Electronic Materials</i>. 2024;6(5):2807-215. doi:<a href=\"https://doi.org/10.1021/acsaelm.3c00055\">10.1021/acsaelm.3c00055</a>","short":"B. Nan, M. Li, Y. Zhang, K. Xiao, K.H. Lim, C. Chang, X. Han, Y. Zuo, J. Li, J. Arbiol, J. Llorca, M. Ibáñez, A. Cabot, ACS Applied Electronic Materials 6 (2024) 2807–215.","ieee":"B. Nan <i>et al.</i>, “Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature,” <i>ACS Applied Electronic Materials</i>, vol. 6, no. 5. American Chemical Society, pp. 2807–215, 2024."},"page":"2807-215","issue":"5","project":[{"name":"Bottom-up Engineering for Thermoelectric Applications","grant_number":"M02889","_id":"9B8804FC-BA93-11EA-9121-9846C619BF3A"},{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"acknowledgement":"Open Access is funded by the Austrian Science Fund (FWF). B.N., M.L., Y.Z., K.X., and X.H. thank the China Scholarship Council (CSC) for the scholarship support. C.C. received funding from the FWF “Lise Meitner Fellowship” grant agreement M 2889-N. M.I. acknowledges the financial support from ISTA and the Werner Siemens Foundation. ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457 and project NANOGEN (PID2020-116093RB-C43) funded by MCIN/AEI/10.13039/501100011033/. ICN2 was supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and was funded by the CERCA Programme/Generalitat de Catalunya. J.L. is a Serra Húnter Fellow and is grateful to the ICREA Academia program and projects MICINN/FEDER PID2021-124572OB-C31 and 2021 SGR 01061. K.H.L. acknowledges support from the National Natural Science Foundation of China (22208293). This study is part of the Advanced Materials programme and was supported by MCIN with funding from European Union NextGenerationEU (PRTR-C17.I1) and by Generalitat de Catalunya.","volume":6,"article_type":"review","file":[{"date_updated":"2024-07-16T07:54:21Z","file_id":"17250","relation":"main_file","checksum":"1f743eaf4fc988cd30102b7c2f12c15d","content_type":"application/pdf","file_name":"2024_ACSAppElecMaterials_Nan.pdf","success":1,"date_created":"2024-07-16T07:54:21Z","file_size":5851865,"creator":"dernst","access_level":"open_access"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"department":[{"_id":"MaIb"}],"publication_status":"published","date_updated":"2025-04-14T09:29:33Z","date_published":"2024-05-28T00:00:00Z","has_accepted_license":"1","type":"journal_article","intvolume":"         6","quality_controlled":"1","date_created":"2023-05-28T22:01:03Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","language":[{"iso":"eng"}]},{"quality_controlled":"1","intvolume":"        24","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_created":"2023-06-11T22:00:40Z","date_published":"2024-08-01T00:00:00Z","type":"journal_article","has_accepted_license":"1","publication_status":"published","department":[{"_id":"JuFi"}],"date_updated":"2025-01-09T07:37:50Z","article_type":"original","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"file":[{"date_created":"2025-01-09T07:36:57Z","file_size":1454406,"creator":"dernst","access_level":"open_access","date_updated":"2025-01-09T07:36:57Z","file_id":"18782","checksum":"ec0582e2b55e2703a7da2686ae0d682e","relation":"main_file","content_type":"application/pdf","file_name":"2024_FoundCompMath_Clozeau.pdf","success":1}],"acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).","volume":24,"citation":{"short":"N. Clozeau, M. Josien, F. Otto, Q. Xu, Foundations of Computational Mathematics 24 (2024) 1305–1387.","ieee":"N. Clozeau, M. Josien, F. Otto, and Q. Xu, “Bias in the representative volume element method: Periodize the ensemble instead of its realizations,” <i>Foundations of Computational Mathematics</i>, vol. 24. Springer Nature, pp. 1305–1387, 2024.","mla":"Clozeau, Nicolas, et al. “Bias in the Representative Volume Element Method: Periodize the Ensemble Instead of Its Realizations.” <i>Foundations of Computational Mathematics</i>, vol. 24, Springer Nature, 2024, pp. 1305–87, doi:<a href=\"https://doi.org/10.1007/s10208-023-09613-y\">10.1007/s10208-023-09613-y</a>.","apa":"Clozeau, N., Josien, M., Otto, F., &#38; Xu, Q. (2024). Bias in the representative volume element method: Periodize the ensemble instead of its realizations. <i>Foundations of Computational Mathematics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10208-023-09613-y\">https://doi.org/10.1007/s10208-023-09613-y</a>","ista":"Clozeau N, Josien M, Otto F, Xu Q. 2024. Bias in the representative volume element method: Periodize the ensemble instead of its realizations. Foundations of Computational Mathematics. 24, 1305–1387.","ama":"Clozeau N, Josien M, Otto F, Xu Q. Bias in the representative volume element method: Periodize the ensemble instead of its realizations. <i>Foundations of Computational Mathematics</i>. 2024;24:1305-1387. doi:<a href=\"https://doi.org/10.1007/s10208-023-09613-y\">10.1007/s10208-023-09613-y</a>","chicago":"Clozeau, Nicolas, Marc Josien, Felix Otto, and Qiang Xu. “Bias in the Representative Volume Element Method: Periodize the Ensemble Instead of Its Realizations.” <i>Foundations of Computational Mathematics</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s10208-023-09613-y\">https://doi.org/10.1007/s10208-023-09613-y</a>."},"page":"1305-1387","external_id":{"isi":["000999623100001"]},"scopus_import":"1","title":"Bias in the representative volume element method: Periodize the ensemble instead of its realizations","article_processing_charge":"Yes (via OA deal)","oa":1,"_id":"13129","status":"public","month":"08","year":"2024","publication":"Foundations of Computational Mathematics","day":"01","publication_identifier":{"issn":["1615-3375"],"eissn":["1615-3383"]},"file_date_updated":"2025-01-09T07:36:57Z","doi":"10.1007/s10208-023-09613-y","OA_place":"publisher","publisher":"Springer Nature","fulldoi":"https://doi.org/10.1007/s10208-023-09613-y","ddc":["510"],"author":[{"full_name":"Clozeau, Nicolas","id":"fea1b376-906f-11eb-847d-b2c0cf46455b","first_name":"Nicolas","last_name":"Clozeau"},{"full_name":"Josien, Marc","first_name":"Marc","last_name":"Josien"},{"full_name":"Otto, Felix","first_name":"Felix","last_name":"Otto"},{"last_name":"Xu","full_name":"Xu, Qiang","first_name":"Qiang"}],"abstract":[{"text":"We study the representative volume element (RVE) method, which is a method to approximately infer the effective behavior ahom of a stationary random medium. The latter is described by a coefficient field a(x) generated from a given ensemble ⟨⋅⟩ and the corresponding linear elliptic operator −∇⋅a∇. In line with the theory of homogenization, the method proceeds by computing d=3 correctors (d denoting the space dimension). To be numerically tractable, this computation has to be done on a finite domain: the so-called representative volume element, i.e., a large box with, say, periodic boundary conditions. The main message of this article is: Periodize the ensemble instead of its realizations. By this, we mean that it is better to sample from a suitably periodized ensemble than to periodically extend the restriction of a realization a(x) from the whole-space ensemble ⟨⋅⟩. We make this point by investigating the bias (or systematic error), i.e., the difference between ahom and the expected value of the RVE method, in terms of its scaling w.r.t. the lateral size L of the box. In case of periodizing a(x), we heuristically argue that this error is generically O(L−1). In case of a suitable periodization of ⟨⋅⟩\r\n, we rigorously show that it is O(L−d). In fact, we give a characterization of the leading-order error term for both strategies and argue that even in the isotropic case it is generically non-degenerate. We carry out the rigorous analysis in the convenient setting of ensembles ⟨⋅⟩\r\n of Gaussian type, which allow for a straightforward periodization, passing via the (integrable) covariance function. This setting has also the advantage of making the Price theorem and the Malliavin calculus available for optimal stochastic estimates of correctors. We actually need control of second-order correctors to capture the leading-order error term. This is due to inversion symmetry when applying the two-scale expansion to the Green function. As a bonus, we present a stream-lined strategy to estimate the error in a higher-order two-scale expansion of the Green function.","lang":"eng"}],"corr_author":"1","isi":1,"OA_type":"hybrid"},{"abstract":[{"lang":"eng","text":"For any 1 ≤ r ≤ ∞, we show that every diffeomorphism of a manifold of the form\r\nR/Z × M is a total renormalization of a Cr-close to identity map. In other words, for\r\nevery diffeomorphism f of R/Z×M, there exists a map g arbitrarily close to identity\r\nsuch that the first return map of g to a domain is conjugate to f and moreover the\r\norbit of this domain is equal to R/Z×M. This enables us to localize near the identity\r\nthe existence of many properties in dynamical systems, such as being Bernoulli for a\r\nsmooth volume form."}],"author":[{"last_name":"Berger","full_name":"Berger, Pierre","first_name":"Pierre"},{"full_name":"Gourmelon, Nicolaz","first_name":"Nicolaz","last_name":"Gourmelon"},{"first_name":"Mathieu","id":"7d296fbe-e2c6-11ee-84d3-d5c2945f9a57","full_name":"Helfter, Mathieu","last_name":"Helfter"}],"OA_type":"green","publication":"Inventiones mathematicae","year":"2024","month":"12","_id":"20838","status":"public","oa":1,"article_processing_charge":"No","title":"Every diffeomorphism is a total renormalization of a close to identity map","scopus_import":"1","fulldoi":"https://doi.org/10.1007/s00222-024-01305-w","publisher":"Springer Nature","OA_place":"repository","doi":"10.1007/s00222-024-01305-w","publication_identifier":{"eissn":["1432-1297"],"issn":["0020-9910"]},"day":"19","volume":239,"external_id":{"arxiv":["2210.09064"]},"citation":{"chicago":"Berger, Pierre, Nicolaz Gourmelon, and Mathieu Helfter. “Every Diffeomorphism Is a Total Renormalization of a Close to Identity Map.” <i>Inventiones Mathematicae</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00222-024-01305-w\">https://doi.org/10.1007/s00222-024-01305-w</a>.","apa":"Berger, P., Gourmelon, N., &#38; Helfter, M. (2024). Every diffeomorphism is a total renormalization of a close to identity map. <i>Inventiones Mathematicae</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00222-024-01305-w\">https://doi.org/10.1007/s00222-024-01305-w</a>","mla":"Berger, Pierre, et al. “Every Diffeomorphism Is a Total Renormalization of a Close to Identity Map.” <i>Inventiones Mathematicae</i>, vol. 239, no. 2, Springer Nature, 2024, pp. 431–68, doi:<a href=\"https://doi.org/10.1007/s00222-024-01305-w\">10.1007/s00222-024-01305-w</a>.","ama":"Berger P, Gourmelon N, Helfter M. Every diffeomorphism is a total renormalization of a close to identity map. <i>Inventiones mathematicae</i>. 2024;239(2):431-468. doi:<a href=\"https://doi.org/10.1007/s00222-024-01305-w\">10.1007/s00222-024-01305-w</a>","ista":"Berger P, Gourmelon N, Helfter M. 2024. Every diffeomorphism is a total renormalization of a close to identity map. Inventiones mathematicae. 239(2), 431–468.","short":"P. Berger, N. Gourmelon, M. Helfter, Inventiones Mathematicae 239 (2024) 431–468.","ieee":"P. Berger, N. Gourmelon, and M. Helfter, “Every diffeomorphism is a total renormalization of a close to identity map,” <i>Inventiones mathematicae</i>, vol. 239, no. 2. Springer Nature, pp. 431–468, 2024."},"page":"431-468","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2210.09064"}],"issue":"2","type":"journal_article","date_published":"2024-12-19T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","date_created":"2025-12-19T10:15:13Z","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"intvolume":"       239","article_type":"original","date_updated":"2025-12-29T12:03:10Z","publication_status":"published","extern":"1"},{"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","date_updated":"2026-01-19T11:03:31Z","extern":"1","publication_status":"published","type":"journal_article","has_accepted_license":"1","date_published":"2024-11-26T00:00:00Z","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_created":"2026-01-08T07:05:57Z","intvolume":"       146","quality_controlled":"1","citation":{"ieee":"Y. Jin <i>et al.</i>, “Light-mediated interconversion between a foldamer and a self-replicator,” <i>Journal of the American Chemical Society</i>, vol. 146, no. 49. American Chemical Society, pp. 33395–33402, 2024.","short":"Y. Jin, P.K. Mandal, J. Wu, A. Kiani, R. Zhao, I. Huc, S. Otto, Journal of the American Chemical Society 146 (2024) 33395–33402.","ista":"Jin Y, Mandal PK, Wu J, Kiani A, Zhao R, Huc I, Otto S. 2024. Light-mediated interconversion between a foldamer and a self-replicator. Journal of the American Chemical Society. 146(49), 33395–33402.","ama":"Jin Y, Mandal PK, Wu J, et al. Light-mediated interconversion between a foldamer and a self-replicator. <i>Journal of the American Chemical Society</i>. 2024;146(49):33395-33402. doi:<a href=\"https://doi.org/10.1021/jacs.4c09114\">10.1021/jacs.4c09114</a>","apa":"Jin, Y., Mandal, P. K., Wu, J., Kiani, A., Zhao, R., Huc, I., &#38; Otto, S. (2024). Light-mediated interconversion between a foldamer and a self-replicator. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.4c09114\">https://doi.org/10.1021/jacs.4c09114</a>","mla":"Jin, Yulong, et al. “Light-Mediated Interconversion between a Foldamer and a Self-Replicator.” <i>Journal of the American Chemical Society</i>, vol. 146, no. 49, American Chemical Society, 2024, pp. 33395–402, doi:<a href=\"https://doi.org/10.1021/jacs.4c09114\">10.1021/jacs.4c09114</a>.","chicago":"Jin, Yulong, Pradeep K Mandal, Juntian Wu, Armin Kiani, Rui Zhao, Ivan Huc, and Sijbren Otto. “Light-Mediated Interconversion between a Foldamer and a Self-Replicator.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/jacs.4c09114\">https://doi.org/10.1021/jacs.4c09114</a>."},"page":"33395-33402","external_id":{"pmid":["39590511"]},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/jacs.4c09114"}],"issue":"49","volume":146,"fulldoi":"https://doi.org/10.1021/jacs.4c09114","ddc":["540"],"doi":"10.1021/jacs.4c09114","OA_place":"publisher","publisher":"American Chemical Society","publication_identifier":{"issn":["0002-7863"],"eissn":["1520-5126"]},"day":"26","PlanS_conform":"1","publication":"Journal of the American Chemical Society","month":"11","_id":"20961","status":"public","year":"2024","article_processing_charge":"Yes (in subscription journal)","oa":1,"scopus_import":"1","title":"Light-mediated interconversion between a foldamer and a self-replicator","OA_type":"hybrid","abstract":[{"lang":"eng","text":"Self-replicating molecules and well-defined folded macromolecules are of great significance in the emergence and evolution of life. How they may interconnect and affect each other remains largely elusive. Here, we demonstrate an abiotic system where a single building block can oligomerize to yield either a self-replicating molecule or a foldamer. Specifically, agitation of a disulfide-based dynamic combinatorial library at moderately elevated pH channels it selectively into a self-replicating hexamer assembled into fibers, after passing through a period where a 15-subunit macrocyclic foldamer existed transiently. Without mechanoagitation or at lower pH, the formation of hexamer fiber is suppressed, resulting in the accumulation of the 15mer foldamer. Foldamer and self-replicator can be interconverted in response to external stimuli, including agitation and a change in pH. Furthermore, upon the addition of a photoacid, the pH of the medium can be controlled by irradiation, driving the switching between replicator and foldamer and allowing a dissipative out-of-equilibrium state to be accessed, using light as a source of energy."}],"pmid":1,"author":[{"first_name":"Yulong","full_name":"Jin, Yulong","last_name":"Jin"},{"first_name":"Pradeep K","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","full_name":"Mandal, Pradeep K","last_name":"Mandal"},{"last_name":"Wu","first_name":"Juntian","full_name":"Wu, Juntian"},{"last_name":"Kiani","first_name":"Armin","full_name":"Kiani, Armin"},{"last_name":"Zhao","first_name":"Rui","full_name":"Zhao, Rui"},{"full_name":"Huc, Ivan","first_name":"Ivan","last_name":"Huc"},{"last_name":"Otto","full_name":"Otto, Sijbren","first_name":"Sijbren"}]},{"fulldoi":"https://doi.org/10.1021/jacs.4c09111","publisher":"American Chemical Society","OA_place":"publisher","doi":"10.1021/jacs.4c09111","publication_identifier":{"eissn":["1520-5126"],"issn":["0002-7863"]},"day":"26","PlanS_conform":"1","publication":"Journal of the American Chemical Society","year":"2024","status":"public","_id":"20962","month":"11","oa":1,"article_processing_charge":"Yes (in subscription journal)","title":"Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium dynamic covalent chemistry","scopus_import":"1","OA_type":"hybrid","keyword":["Fibers","Foldamers","Macrocycles","Monomers","Peptides","Proteins"],"abstract":[{"text":"Systems chemistry has emerged as a useful paradigm to access structures and phenomena typically exhibited by living systems, including complex molecular systems such as self-replicators and foldamers. As we progress further toward the noncovalent synthesis of life-like systems, and eventually life itself, it is necessary to gain control over assembly pathways. Dissipative chemical fueling has enabled access to stable populations of (self-assembled) structures that would normally form only transiently. Here, we report a synthetic dynamic combinatorial library, made from a single structurally simple building block, from which a self-replicator and a foldamer can emerge along two distinct and competing pathways through an inter- or intramolecular assembly process, respectively. A fueled chemical reaction cycle is then set up to generate the foldamer transiently, in the presence of the self-replicator. The partitioning of the building block between the folding and self-replication pathways and the duration of the fueled reaction cycles are controlled by adjusting the amount of the chemical fuel. An out-of-equilibrium steady state involving the two assemblies could also be achieved by using a continuous stirred tank reactor with inflow and outflow of material. This work connects the domains of folding and self-replication in synthetic systems through dissipative out-of-equilibrium chemistry. It demonstrates that foldamers and self-replicators, formed from the same building block, can stably coexist if the system is continuously supplied with energy, while at equilibrium, the Gibbs phase rule prohibits such coexistence.","lang":"eng"}],"pmid":1,"author":[{"first_name":"Ankush","full_name":"Sood, Ankush","last_name":"Sood"},{"first_name":"Pradeep K","orcid":"0000-0001-5996-956X","full_name":"Mandal, Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal"},{"last_name":"Ottelé","first_name":"Jim","full_name":"Ottelé, Jim"},{"last_name":"Wu","full_name":"Wu, Juntian","first_name":"Juntian"},{"first_name":"Marcel","full_name":"Eleveld, Marcel","last_name":"Eleveld"},{"last_name":"Hatai","first_name":"Joydev","full_name":"Hatai, Joydev"},{"last_name":"Pappas","first_name":"Charalampos G.","full_name":"Pappas, Charalampos G."},{"full_name":"Huc, Ivan","first_name":"Ivan","last_name":"Huc"},{"first_name":"Sijbren","full_name":"Otto, Sijbren","last_name":"Otto"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","date_updated":"2026-01-19T10:57:53Z","extern":"1","publication_status":"published","has_accepted_license":"1","type":"journal_article","date_published":"2024-11-26T00:00:00Z","oa_version":"Published Version","date_created":"2026-01-08T07:06:27Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"quality_controlled":"1","intvolume":"       146","external_id":{"pmid":["39590110"]},"citation":{"chicago":"Sood, Ankush, Pradeep K Mandal, Jim Ottelé, Juntian Wu, Marcel Eleveld, Joydev Hatai, Charalampos G. Pappas, Ivan Huc, and Sijbren Otto. “Simultaneous Formation of a Foldamer and a Self-Replicator by out-of-Equilibrium Dynamic Covalent Chemistry.” <i>Journal of the American Chemical Society</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/jacs.4c09111\">https://doi.org/10.1021/jacs.4c09111</a>.","mla":"Sood, Ankush, et al. “Simultaneous Formation of a Foldamer and a Self-Replicator by out-of-Equilibrium Dynamic Covalent Chemistry.” <i>Journal of the American Chemical Society</i>, vol. 146, no. 49, American Chemical Society, 2024, pp. 33386–94, doi:<a href=\"https://doi.org/10.1021/jacs.4c09111\">10.1021/jacs.4c09111</a>.","apa":"Sood, A., Mandal, P. K., Ottelé, J., Wu, J., Eleveld, M., Hatai, J., … Otto, S. (2024). Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium dynamic covalent chemistry. <i>Journal of the American Chemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.4c09111\">https://doi.org/10.1021/jacs.4c09111</a>","ama":"Sood A, Mandal PK, Ottelé J, et al. Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium dynamic covalent chemistry. <i>Journal of the American Chemical Society</i>. 2024;146(49):33386-33394. doi:<a href=\"https://doi.org/10.1021/jacs.4c09111\">10.1021/jacs.4c09111</a>","ista":"Sood A, Mandal PK, Ottelé J, Wu J, Eleveld M, Hatai J, Pappas CG, Huc I, Otto S. 2024. Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium dynamic covalent chemistry. Journal of the American Chemical Society. 146(49), 33386–33394.","short":"A. Sood, P.K. Mandal, J. Ottelé, J. Wu, M. Eleveld, J. Hatai, C.G. Pappas, I. Huc, S. Otto, Journal of the American Chemical Society 146 (2024) 33386–33394.","ieee":"A. Sood <i>et al.</i>, “Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium dynamic covalent chemistry,” <i>Journal of the American Chemical Society</i>, vol. 146, no. 49. American Chemical Society, pp. 33386–33394, 2024."},"page":"33386-33394","main_file_link":[{"url":"https://doi.org/10.1021/jacs.4c09111","open_access":"1"}],"issue":"49","volume":146},{"OA_type":"hybrid","abstract":[{"lang":"eng","text":"A biotinylated helical aromatic oligoamide foldamer equivalent in size to a 24mer peptide was designed without any prejudice other than to display various polar and hydrophobic side chains at its surface. It was synthesized on solid phase, its P- and M-helical conformers were separated by HPLC on a chiral stationary phase, and the solid state structure of a non-biotinylated analogue was elucidated by X-ray crystallography. Pull-down experiments from a yeast cell lysate using the foldamer as a bait followed by proteomic analysis revealed potential protein binding partners. Three of these proteins were recombinantly expressed. Biolayer interferometry showed submicromolar binding demonstrating the potential of a given foldamer to have affinity for certain proteins in the absence of design considerations. Yet, binding selectivity was low in all three cases since both P- and M-conformers bound to the proteins with similar affinities."}],"author":[{"first_name":"Sunbum","full_name":"Kwon, Sunbum","last_name":"Kwon"},{"first_name":"Vasily","full_name":"Morozov, Vasily","last_name":"Morozov"},{"full_name":"Wang, Lingfei","first_name":"Lingfei","last_name":"Wang"},{"last_name":"Mandal","orcid":"0000-0001-5996-956X","first_name":"Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","full_name":"Mandal, Pradeep K"},{"last_name":"Chaignepain","full_name":"Chaignepain, Stéphane","first_name":"Stéphane"},{"last_name":"Douat","first_name":"Céline","full_name":"Douat, Céline"},{"first_name":"Ivan","full_name":"Huc, Ivan","last_name":"Huc"}],"pmid":1,"publisher":"Royal Society of Chemistry","OA_place":"publisher","doi":"10.1039/d4ob01436g","fulldoi":"https://doi.org/10.1039/d4ob01436g","license":"https://creativecommons.org/licenses/by/3.0/","day":"30","PlanS_conform":"1","publication_identifier":{"eissn":["1477-0539"],"issn":["1477-0520"]},"year":"2024","status":"public","_id":"20967","month":"10","publication":"Organic & Biomolecular Chemistry","title":"Interrogating the potential of helical aromatic foldamers for protein recognition","scopus_import":"1","oa":1,"article_processing_charge":"Yes (in subscription journal)","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1039/D4OB01436G"}],"external_id":{"pmid":["39501876"]},"page":"9342-9347","citation":{"chicago":"Kwon, Sunbum, Vasily Morozov, Lingfei Wang, Pradeep K Mandal, Stéphane Chaignepain, Céline Douat, and Ivan Huc. “Interrogating the Potential of Helical Aromatic Foldamers for Protein Recognition.” <i>Organic &#38; Biomolecular Chemistry</i>. Royal Society of Chemistry, 2024. <a href=\"https://doi.org/10.1039/d4ob01436g\">https://doi.org/10.1039/d4ob01436g</a>.","short":"S. Kwon, V. Morozov, L. Wang, P.K. Mandal, S. Chaignepain, C. Douat, I. Huc, Organic &#38; Biomolecular Chemistry 22 (2024) 9342–9347.","ieee":"S. Kwon <i>et al.</i>, “Interrogating the potential of helical aromatic foldamers for protein recognition,” <i>Organic &#38; Biomolecular Chemistry</i>, vol. 22, no. 48. Royal Society of Chemistry, pp. 9342–9347, 2024.","apa":"Kwon, S., Morozov, V., Wang, L., Mandal, P. K., Chaignepain, S., Douat, C., &#38; Huc, I. (2024). Interrogating the potential of helical aromatic foldamers for protein recognition. <i>Organic &#38; Biomolecular Chemistry</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d4ob01436g\">https://doi.org/10.1039/d4ob01436g</a>","mla":"Kwon, Sunbum, et al. “Interrogating the Potential of Helical Aromatic Foldamers for Protein Recognition.” <i>Organic &#38; Biomolecular Chemistry</i>, vol. 22, no. 48, Royal Society of Chemistry, 2024, pp. 9342–47, doi:<a href=\"https://doi.org/10.1039/d4ob01436g\">10.1039/d4ob01436g</a>.","ista":"Kwon S, Morozov V, Wang L, Mandal PK, Chaignepain S, Douat C, Huc I. 2024. Interrogating the potential of helical aromatic foldamers for protein recognition. Organic &#38; Biomolecular Chemistry. 22(48), 9342–9347.","ama":"Kwon S, Morozov V, Wang L, et al. Interrogating the potential of helical aromatic foldamers for protein recognition. <i>Organic &#38; Biomolecular Chemistry</i>. 2024;22(48):9342-9347. doi:<a href=\"https://doi.org/10.1039/d4ob01436g\">10.1039/d4ob01436g</a>"},"issue":"48","volume":22,"article_type":"original","tmp":{"name":"Creative Commons Attribution 3.0 Unported (CC BY 3.0)","legal_code_url":"https://creativecommons.org/licenses/by/3.0/legalcode","short":"CC BY (3.0)","image":"/images/cc_by.png"},"extern":"1","publication_status":"published","date_updated":"2026-01-20T06:56:44Z","date_published":"2024-10-30T00:00:00Z","has_accepted_license":"1","type":"journal_article","quality_controlled":"1","intvolume":"        22","date_created":"2026-01-11T14:32:23Z","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}]},{"OA_type":"gold","article_number":"92","author":[{"full_name":"Labbe, Ivo","first_name":"Ivo","last_name":"Labbe"},{"last_name":"Greene","first_name":"Jenny E.","full_name":"Greene, Jenny E."},{"last_name":"Bezanson","full_name":"Bezanson, Rachel","first_name":"Rachel"},{"last_name":"Fujimoto","first_name":"Seiji","full_name":"Fujimoto, Seiji"},{"full_name":"Furtak, Lukas J.","first_name":"Lukas J.","last_name":"Furtak"},{"last_name":"Goulding","first_name":"Andy D.","full_name":"Goulding, Andy D."},{"first_name":"Jorryt J","orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","last_name":"Matthee"},{"last_name":"Naidu","full_name":"Naidu, Rohan P.","first_name":"Rohan P."},{"last_name":"Oesch","first_name":"Pascal A.","full_name":"Oesch, Pascal A."},{"last_name":"Atek","full_name":"Atek, Hakim","first_name":"Hakim"},{"full_name":"Brammer, Gabriel","first_name":"Gabriel","last_name":"Brammer"},{"last_name":"Chemerynska","full_name":"Chemerynska, Iryna","first_name":"Iryna"},{"last_name":"Coe","first_name":"Dan","full_name":"Coe, Dan"},{"full_name":"Cutler, Sam E.","first_name":"Sam E.","last_name":"Cutler"},{"last_name":"Dayal","full_name":"Dayal, Pratika","first_name":"Pratika"},{"first_name":"Robert","full_name":"Feldmann, Robert","last_name":"Feldmann"},{"full_name":"Franx, Marijn","first_name":"Marijn","last_name":"Franx"},{"full_name":"Glazebrook, Karl","first_name":"Karl","last_name":"Glazebrook"},{"last_name":"Leja","first_name":"Joel","full_name":"Leja, Joel"},{"last_name":"Maseda","first_name":"Michael","full_name":"Maseda, Michael"},{"first_name":"Danilo","full_name":"Marchesini, Danilo","last_name":"Marchesini"},{"full_name":"Nanayakkara, Themiya","first_name":"Themiya","last_name":"Nanayakkara"},{"last_name":"Nelson","full_name":"Nelson, Erica J.","first_name":"Erica J."},{"first_name":"Richard","full_name":"Pan, Richard","last_name":"Pan"},{"full_name":"Papovich, Casey","first_name":"Casey","last_name":"Papovich"},{"first_name":"Sedona H.","full_name":"Price, Sedona H.","last_name":"Price"},{"first_name":"Katherine A.","full_name":"Suess, Katherine A.","last_name":"Suess"},{"last_name":"Wang","full_name":"Wang, Bingjie 冰洁","first_name":"Bingjie 冰洁"},{"last_name":"Weaver","full_name":"Weaver, John R.","first_name":"John R."},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"},{"first_name":"Christina C.","full_name":"Williams, Christina C.","last_name":"Williams"},{"full_name":"Zitrin, Adi","first_name":"Adi","last_name":"Zitrin"}],"abstract":[{"text":"The James Webb Space Telescope (JWST) is revolutionizing our knowledge of z > 5 galaxies and their actively accreting black holes. Using the JWST Cycle 1 Treasury program Ultradeep NIRSpec and NIRCam Observations before the Epoch of Reionization (UNCOVER) in the lensing field A2744, we report the identification of a sample of little red dots at 3 < zphot < 7 that likely contain highly reddened accreting supermassive black holes. Using a NIRCam-only selection to F444W < 27.7 mag, we find 26 sources over the ∼45 arcmin^2 field that are blue in F115W − F200W ∼ 0 (or βUV ∼ –2.0 for fλ ∝ λ^β), red in F200W − F444W = 1−4 (βopt ∼ +2.0), and are dominated by a point-source-like central component. Of the 20 sources with deep Atacama Large Millimeter/submillimeter Array (ALMA) 1.2 mm coverage, none are detected individually or in a stack. For the majority of the sample, spectral energy distribution fits to the JWST+ALMA observations prefer models with hot dust rather than obscured star formation to reproduce the red NIRCam colors and ALMA 1.2 mm nondetections. While compact dusty star formation cannot be ruled out, the combination of extremely small sizes (〈re〉 ≈ 50 pc after correction for magnification), red rest-frame optical slopes, and hot dust can be explained by reddened broad-line active galactic nuclei (AGNs). Our targets have faint M1450 ≈ −14 to −18 mag but inferred bolometric luminosities of Lbol = 10^43–10^46 erg s^−1, reflecting their obscured nature. If the candidates are confirmed as AGNs with upcoming UNCOVER spectroscopy, then we have found an abundant population of reddened luminous AGNs that are at least ten times more numerous than UV-luminous AGNs at the same intrinsic bolometric luminosity.","lang":"eng"}],"publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"day":"26","PlanS_conform":"1","ddc":["520"],"fulldoi":"https://doi.org/10.3847/1538-4357/ad3551","publisher":"IOP Publishing","doi":"10.3847/1538-4357/ad3551","OA_place":"publisher","file_date_updated":"2026-02-10T06:44:24Z","oa":1,"article_processing_charge":"Yes","title":"UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA","scopus_import":"1","DOAJ_listed":"1","publication":"The Astrophysical Journal","year":"2024","_id":"21064","status":"public","month":"12","external_id":{"arxiv":["2306.07320"]},"citation":{"chicago":"Labbe, Ivo, Jenny E. Greene, Rachel Bezanson, Seiji Fujimoto, Lukas J. Furtak, Andy D. Goulding, Jorryt J Matthee, et al. “UNCOVER: Candidate Red Active Galactic Nuclei at 3 &#60; z &#60; 7 with JWST and ALMA.” <i>The Astrophysical Journal</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad3551\">https://doi.org/10.3847/1538-4357/ad3551</a>.","ieee":"I. Labbe <i>et al.</i>, “UNCOVER: Candidate red active galactic nuclei at 3 &#60; z &#60; 7 with JWST and ALMA,” <i>The Astrophysical Journal</i>, vol. 978. IOP Publishing, 2024.","short":"I. Labbe, J.E. Greene, R. Bezanson, S. Fujimoto, L.J. Furtak, A.D. Goulding, J.J. Matthee, R.P. Naidu, P.A. Oesch, H. Atek, G. Brammer, I. Chemerynska, D. Coe, S.E. Cutler, P. Dayal, R. Feldmann, M. Franx, K. Glazebrook, J. Leja, M. Maseda, D. Marchesini, T. Nanayakkara, E.J. Nelson, R. Pan, C. Papovich, S.H. Price, K.A. Suess, B.冰洁 Wang, J.R. Weaver, K.E. Whitaker, C.C. Williams, A. Zitrin, The Astrophysical Journal 978 (2024).","ista":"Labbe I, Greene JE, Bezanson R, Fujimoto S, Furtak LJ, Goulding AD, Matthee JJ, Naidu RP, Oesch PA, Atek H, Brammer G, Chemerynska I, Coe D, Cutler SE, Dayal P, Feldmann R, Franx M, Glazebrook K, Leja J, Maseda M, Marchesini D, Nanayakkara T, Nelson EJ, Pan R, Papovich C, Price SH, Suess KA, Wang B冰洁, Weaver JR, Whitaker KE, Williams CC, Zitrin A. 2024. UNCOVER: Candidate red active galactic nuclei at 3 &#60; z &#60; 7 with JWST and ALMA. The Astrophysical Journal. 978, 92.","ama":"Labbe I, Greene JE, Bezanson R, et al. UNCOVER: Candidate red active galactic nuclei at 3 &#60; z &#60; 7 with JWST and ALMA. <i>The Astrophysical Journal</i>. 2024;978. doi:<a href=\"https://doi.org/10.3847/1538-4357/ad3551\">10.3847/1538-4357/ad3551</a>","mla":"Labbe, Ivo, et al. “UNCOVER: Candidate Red Active Galactic Nuclei at 3 &#60; z &#60; 7 with JWST and ALMA.” <i>The Astrophysical Journal</i>, vol. 978, 92, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad3551\">10.3847/1538-4357/ad3551</a>.","apa":"Labbe, I., Greene, J. E., Bezanson, R., Fujimoto, S., Furtak, L. J., Goulding, A. D., … Zitrin, A. (2024). UNCOVER: Candidate red active galactic nuclei at 3 &#60; z &#60; 7 with JWST and ALMA. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ad3551\">https://doi.org/10.3847/1538-4357/ad3551</a>"},"acknowledgement":"I.L. acknowledges support from Australian Research Council Future Fellowship FT220100798. J.E.G. and A.D.G acknowledge support from NSF/AAG grant #1007094, and J.E.G. also acknowledges support from NSF/AAG grant #1007052. L.J.F. and A.Z. acknowledge support by Grant No. 2020750 from the United States–Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Ministry of Science & Technology of Israel. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (“ODIN”) and from the European Commission’s and University of Groningen’s CO-FUND Rosalind Franklin program. R.P.N. acknowledges funding from JWST programs GO-1933 and GO-2279. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. This paper makes use of the ALMA data: ADS/JAO. ALMA #2022.1.00073.S, 2018.1.00035.L, and 2013.1.00999.S. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation.","volume":978,"date_updated":"2026-02-10T06:49:49Z","department":[{"_id":"JoMa"}],"publication_status":"published","file":[{"access_level":"open_access","date_created":"2026-02-10T06:44:24Z","creator":"dernst","file_size":5041924,"file_name":"2024_AstrophysicalJourn_Labbe.pdf","content_type":"application/pdf","success":1,"date_updated":"2026-02-10T06:44:24Z","checksum":"825c35ebd26e292c8a5c2bffac327854","relation":"main_file","file_id":"21201"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"article_type":"original","oa_version":"Published Version","date_created":"2026-01-28T15:26:12Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"intvolume":"       978","has_accepted_license":"1","type":"journal_article","date_published":"2024-12-26T00:00:00Z"},{"corr_author":"1","main_file_link":[{"url":"https://doi.org/10.5281/ZENODO.13934991","open_access":"1"}],"citation":{"chicago":"Santana de Freitas Amaral, Miguel. “Archaeal_membranes : Code and Examples.” Zenodo, 2024. <a href=\"https://doi.org/10.5281/ZENODO.13934991\">https://doi.org/10.5281/ZENODO.13934991</a>.","ista":"Santana de Freitas Amaral M. 2024. archaeal_membranes : code and examples, Zenodo, <a href=\"https://doi.org/10.5281/ZENODO.13934991\">10.5281/ZENODO.13934991</a>.","ama":"Santana de Freitas Amaral M. archaeal_membranes : code and examples. 2024. doi:<a href=\"https://doi.org/10.5281/ZENODO.13934991\">10.5281/ZENODO.13934991</a>","mla":"Santana de Freitas Amaral, Miguel. <i>Archaeal_membranes : Code and Examples</i>. Zenodo, 2024, doi:<a href=\"https://doi.org/10.5281/ZENODO.13934991\">10.5281/ZENODO.13934991</a>.","apa":"Santana de Freitas Amaral, M. (2024). archaeal_membranes : code and examples. Zenodo. <a href=\"https://doi.org/10.5281/ZENODO.13934991\">https://doi.org/10.5281/ZENODO.13934991</a>","ieee":"M. Santana de Freitas Amaral, “archaeal_membranes : code and examples.” Zenodo, 2024.","short":"M. Santana de Freitas Amaral, (2024)."},"OA_type":"green","related_material":{"record":[{"status":"public","id":"21251","relation":"used_for_analysis_in"}]},"abstract":[{"text":"No description provided.","lang":"eng"}],"author":[{"first_name":"Miguel","full_name":"Santana de Freitas Amaral, Miguel","id":"4f2d02dd-47a9-11ec-ad10-82820ed3f501","last_name":"Santana de Freitas Amaral"}],"publisher":"Zenodo","OA_place":"repository","doi":"10.5281/ZENODO.13934991","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"fulldoi":"https://doi.org/10.5281/ZENODO.13934991","department":[{"_id":"AnSa"}],"day":"15","date_updated":"2026-02-23T11:49:05Z","year":"2024","date_published":"2024-10-15T00:00:00Z","_id":"21304","status":"public","month":"10","has_accepted_license":"1","type":"research_data_reference","title":"archaeal_membranes : code and examples","oa_version":"Published Version","oa":1,"date_created":"2026-02-17T12:52:26Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No"}]