[{"day":"01","date_published":"2024-04-01T00:00:00Z","external_id":{"arxiv":["2210.12060"],"isi":["001118972500001"]},"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1007/s00440-023-01229-1","isi":1,"title":"Mesoscopic central limit theorem for non-Hermitian random matrices","abstract":[{"text":"We prove that the mesoscopic linear statistics ∑if(na(σi−z0)) of the eigenvalues {σi}i of large n×n non-Hermitian random matrices with complex centred i.i.d. entries are asymptotically Gaussian for any H20-functions f around any point z0 in the bulk of the spectrum on any mesoscopic scale 0Probability Theory and Related Fields, vol. 188. Springer Nature, pp. 1131–1182, 2024.","apa":"Cipolloni, G., Erdös, L., & Schröder, D. J. (2024). Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. Springer Nature. https://doi.org/10.1007/s00440-023-01229-1","short":"G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields 188 (2024) 1131–1182.","chicago":"Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Mesoscopic Central Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related Fields. Springer Nature, 2024. https://doi.org/10.1007/s00440-023-01229-1.","ista":"Cipolloni G, Erdös L, Schröder DJ. 2024. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 188, 1131–1182.","mla":"Cipolloni, Giorgio, et al. “Mesoscopic Central Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related Fields, vol. 188, Springer Nature, 2024, pp. 1131–82, doi:10.1007/s00440-023-01229-1.","ama":"Cipolloni G, Erdös L, Schröder DJ. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 2024;188:1131-1182. doi:10.1007/s00440-023-01229-1"},"publication_identifier":{"eissn":["1432-2064"],"issn":["0178-8051"]},"volume":188,"ec_funded":1,"arxiv":1,"quality_controlled":"1","acknowledgement":"The authors are grateful to Joscha Henheik for his help with the formulas in Appendix B.\r\nLászló Erdős supported by ERC Advanced Grant “RMTBeyond” No. 101020331. Dominik Schröder supported by the SNSF Ambizione Grant PZ00P2 209089."},{"keyword":["Mechanical Engineering","Mechanics of Materials","General Materials Science"],"day":"04","date_published":"2024-01-04T00:00:00Z","external_id":{"pmid":["37555532"],"isi":["001085681000001"]},"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1002/adma.202305128","isi":1,"_id":"14435","status":"public","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Wiley","doi":"10.1002/adma.202305128","title":"A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries","abstract":[{"lang":"eng","text":"Low‐cost, safe, and environmental‐friendly rechargeable aqueous zinc‐ion batteries (ZIBs) are promising as next‐generation energy storage devices for wearable electronics among other applications. However, sluggish ionic transport kinetics and the unstable electrode structure during ionic insertion/extraction hampers their deployment. Herein,  we propose a new cathode material based on a layered metal chalcogenide (LMC), bismuth telluride (Bi2Te3), coated with polypyrrole (PPy). Taking advantage of the PPy coating, the Bi2Te3@PPy composite presents strong ionic absorption affinity, high oxidation resistance, and high structural stability. The ZIBs based on Bi2Te3@PPy cathodes exhibit high capacities and ultra‐long lifespans of over 5000 cycles. They also present outstanding stability even under bending. In addition,  we analyze here the reaction mechanism using in situ X‐ray diffraction, X‐ray photoelectron spectroscopy, and computational tools and demonstrate that, in the aqueous system, Zn2+ is not inserted into the cathode as previously assumed. In contrast, proton charge storage dominates the process. Overall, this work not only shows the great potential of LMCs as ZIBs cathode materials and the advantages of PPy coating, but also clarifies the charge/discharge mechanism in rechargeable ZIBs based on LMCs."}],"pmid":1,"date_updated":"2025-04-15T06:36:40Z","month":"01","intvolume":" 36","oa_version":"None","issue":"1","year":"2024","article_processing_charge":"No","author":[{"full_name":"Zeng, Guifang","first_name":"Guifang","last_name":"Zeng"},{"last_name":"Sun","first_name":"Qing","full_name":"Sun, Qing"},{"first_name":"Sharona","full_name":"Horta, Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta"},{"first_name":"Shang","full_name":"Wang, Shang","last_name":"Wang"},{"first_name":"Xuan","full_name":"Lu, Xuan","last_name":"Lu"},{"last_name":"Zhang","full_name":"Zhang, Chaoyue","first_name":"Chaoyue"},{"first_name":"Jing","full_name":"Li, Jing","last_name":"Li"},{"last_name":"Li","full_name":"Li, Junshan","first_name":"Junshan"},{"last_name":"Ci","first_name":"Lijie","full_name":"Ci, Lijie"},{"first_name":"Yanhong","full_name":"Tian, Yanhong","last_name":"Tian"},{"last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"}],"publication_status":"published","article_type":"original","volume":36,"publication_identifier":{"issn":["0935-9648"],"eissn":["1521-4095"]},"quality_controlled":"1","article_number":"2305128","acknowledgement":"G.Z. and Q.S. contributed equally to this work. This work was supported by the National Natural Science Foundation of China (52105329, 52175300) and the Heilongjiang Provincial Natural Science Foundation of China (LH2022E059). G.Z., X.L., and C.Z. thank the China Scholarship Council (CSC) for the scholarship support. This research was supported by the Scientific Service Units of ISTA through resources provided by the Electron Microscopy Facility. S.H. and M.I. acknowledge funding by ISTA and Werner Siemens.","date_created":"2023-10-17T10:53:56Z","department":[{"_id":"MaIb"}],"scopus_import":"1","publication":"Advanced Materials","citation":{"chicago":"Zeng, Guifang, Qing Sun, Sharona Horta, Shang Wang, Xuan Lu, Chaoyue Zhang, Jing Li, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials. Wiley, 2024. https://doi.org/10.1002/adma.202305128.","short":"G. Zeng, Q. Sun, S. Horta, S. Wang, X. Lu, C. Zhang, J. Li, J. Li, L. Ci, Y. Tian, M. Ibáñez, A. Cabot, Advanced Materials 36 (2024).","apa":"Zeng, G., Sun, Q., Horta, S., Wang, S., Lu, X., Zhang, C., … Cabot, A. (2024). A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. Wiley. https://doi.org/10.1002/adma.202305128","ieee":"G. Zeng et al., “A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries,” Advanced Materials, vol. 36, no. 1. Wiley, 2024.","mla":"Zeng, Guifang, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials, vol. 36, no. 1, 2305128, Wiley, 2024, doi:10.1002/adma.202305128.","ama":"Zeng G, Sun Q, Horta S, et al. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 2024;36(1). doi:10.1002/adma.202305128","ista":"Zeng G, Sun Q, Horta S, Wang S, Lu X, Zhang C, Li J, Li J, Ci L, Tian Y, Ibáñez M, Cabot A. 2024. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 36(1), 2305128."},"acknowledged_ssus":[{"_id":"EM-Fac"}]},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"day":"01","date_published":"2024-04-01T00:00:00Z","external_id":{"isi":["001084334300001"]},"file":[{"file_size":2847929,"date_updated":"2024-07-16T08:13:24Z","checksum":"e63271b1d57c1f03c1d993fd62cba59c","relation":"main_file","date_created":"2024-07-16T08:13:24Z","success":1,"creator":"dernst","access_level":"open_access","file_id":"17252","file_name":"2024_PlantGrowthReg_Bieleszova.pdf","content_type":"application/pdf"}],"fulldoi":"https://doi.org/10.1007/s10725-023-01083-0","isi":1,"language":[{"iso":"eng"}],"type":"journal_article","_id":"14447","status":"public","publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1007/s10725-023-01083-0","title":"New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana","file_date_updated":"2024-07-16T08:13:24Z","abstract":[{"lang":"eng","text":"Auxin belongs among major phytohormones and governs multiple aspects of plant growth and development. The establishment of auxin concentration gradients, determines, among other processes, plant organ positioning and growth responses to environmental stimuli.\r\nHerein we report the synthesis of new NBD- or DNS-labelled IAA derivatives and the elucidation of their biological activity, fluorescence properties and subcellular accumulation patterns in planta. These novel compounds did not show auxin-like activity, but instead antagonized physiological auxin effects. The DNS-labelled derivatives FL5 and FL6 showed strong anti-auxin activity in roots and hypocotyls, which also occurred at the level of gene transcription as confirmed by quantitative PCR analysis. The auxin antagonism of our derivatives was further demonstrated in vitro using an SPR-based binding assay. The NBD-labelled compound FL4 with the best fluorescence properties proved to be unsuitable to study auxin accumulation patterns in planta. On the other hand, the strongest anti-auxin activity possessing compounds FL5 and FL6 could be useful to study binding mechanisms to auxin receptors and for manipulations of auxin-regulated processes."}],"license":"https://creativecommons.org/licenses/by/4.0/","page":"589-602","date_updated":"2024-07-16T08:13:39Z","month":"04","intvolume":" 102","oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","oa":1,"year":"2024","ddc":["580"],"publication_status":"published","article_type":"original","author":[{"last_name":"Bieleszová","first_name":"Kristýna","full_name":"Bieleszová, Kristýna"},{"first_name":"Pavel","full_name":"Hladík, Pavel","last_name":"Hladík"},{"full_name":"Kubala, Martin","first_name":"Martin","last_name":"Kubala"},{"last_name":"Napier","first_name":"Richard","full_name":"Napier, Richard"},{"last_name":"Brunoni","first_name":"Federica","full_name":"Brunoni, Federica"},{"id":"0AE74790-0E0B-11E9-ABC7-1ACFE5697425","full_name":"Gelová, Zuzana","orcid":"0000-0003-4783-1752","first_name":"Zuzana","last_name":"Gelová"},{"last_name":"Fiedler","id":"7c417475-8972-11ed-ae7b-8b674ca26986","full_name":"Fiedler, Lukas","first_name":"Lukas"},{"last_name":"Kulich","first_name":"Ivan","full_name":"Kulich, Ivan","id":"57a1567c-8314-11eb-9063-c9ddc3451a54"},{"last_name":"Strnad","first_name":"Miroslav","full_name":"Strnad, Miroslav"},{"last_name":"Doležal","full_name":"Doležal, Karel","first_name":"Karel"},{"last_name":"Novák","first_name":"Ondřej","full_name":"Novák, Ondřej"},{"full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml"},{"last_name":"Žukauskaitė","full_name":"Žukauskaitė, Asta","first_name":"Asta"}],"publication_identifier":{"eissn":["1573-5087"],"issn":["0167-6903"]},"volume":102,"quality_controlled":"1","acknowledgement":"The authors would like to thank Karolína Kubiasová and Iñigo Saiz-Fernández for valuable scientific discussions. Open access publishing supported by the National Technical Library in Prague. This work was supported by the Palacký University Olomouc Young Researcher Grant Competition (JG_2020_002), by the Internal Grant Agency of Palacký University Olomouc (IGA_PrF_2023_016, IGA_PrF_2023_031), by the Ministry of Education, Youth and Sports of the Czech Republic through the European Regional Development Fund-Project Plants as a tool for sustainable global development (CZ.02.1.01/0.0/0.0/16_019/0000827) and the project Support of mobility at Palacký University Olomouc II. (CZ.02.2.69/0.0/0.0/18_053/0016919). The Biacore T200 SPR instrument was provided by the WISB Research Technology Facility within the School of Life Sciences, University of Warwick.","scopus_import":"1","department":[{"_id":"JiFr"}],"date_created":"2023-10-22T22:01:15Z","publication":"Plant Growth Regulation","citation":{"mla":"Bieleszová, Kristýna, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation, vol. 102, Springer Nature, 2024, pp. 589–602, doi:10.1007/s10725-023-01083-0.","ama":"Bieleszová K, Hladík P, Kubala M, et al. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 2024;102:589-602. doi:10.1007/s10725-023-01083-0","ista":"Bieleszová K, Hladík P, Kubala M, Napier R, Brunoni F, Gelová Z, Fiedler L, Kulich I, Strnad M, Doležal K, Novák O, Friml J, Žukauskaitė A. 2024. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 102, 589–602.","chicago":"Bieleszová, Kristýna, Pavel Hladík, Martin Kubala, Richard Napier, Federica Brunoni, Zuzana Gelová, Lukas Fiedler, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation. Springer Nature, 2024. https://doi.org/10.1007/s10725-023-01083-0.","short":"K. Bieleszová, P. Hladík, M. Kubala, R. Napier, F. Brunoni, Z. Gelová, L. Fiedler, I. Kulich, M. Strnad, K. Doležal, O. Novák, J. Friml, A. Žukauskaitė, Plant Growth Regulation 102 (2024) 589–602.","ieee":"K. Bieleszová et al., “New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana,” Plant Growth Regulation, vol. 102. Springer Nature, pp. 589–602, 2024.","apa":"Bieleszová, K., Hladík, P., Kubala, M., Napier, R., Brunoni, F., Gelová, Z., … Žukauskaitė, A. (2024). New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. Springer Nature. https://doi.org/10.1007/s10725-023-01083-0"},"has_accepted_license":"1"},{"publication_status":"published","article_type":"original","author":[{"id":"2CEB641C-A400-11E9-A717-D712E6697425","first_name":"Federico","orcid":"0000-0002-6269-5149","full_name":"Cornalba, Federico","last_name":"Cornalba"},{"full_name":"Disselkamp, Constantin","first_name":"Constantin","last_name":"Disselkamp"},{"full_name":"Scassola, Davide","first_name":"Davide","last_name":"Scassola"},{"full_name":"Helf, Christopher","first_name":"Christopher","last_name":"Helf"}],"ddc":["000"],"article_processing_charge":"Yes (via OA deal)","year":"2024","oa":1,"month":"01","issue":"2","oa_version":"Published Version","intvolume":" 36","corr_author":"1","citation":{"chicago":"Cornalba, Federico, Constantin Disselkamp, Davide Scassola, and Christopher Helf. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications. Springer Nature, 2024. https://doi.org/10.1007/s00521-023-09033-7.","short":"F. Cornalba, C. Disselkamp, D. Scassola, C. Helf, Neural Computing and Applications 36 (2024) 617–637.","ieee":"F. Cornalba, C. Disselkamp, D. Scassola, and C. Helf, “Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading,” Neural Computing and Applications, vol. 36, no. 2. Springer Nature, pp. 617–637, 2024.","apa":"Cornalba, F., Disselkamp, C., Scassola, D., & Helf, C. (2024). Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. Springer Nature. https://doi.org/10.1007/s00521-023-09033-7","ama":"Cornalba F, Disselkamp C, Scassola D, Helf C. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 2024;36(2):617-637. doi:10.1007/s00521-023-09033-7","mla":"Cornalba, Federico, et al. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications, vol. 36, no. 2, Springer Nature, 2024, pp. 617–37, doi:10.1007/s00521-023-09033-7.","ista":"Cornalba F, Disselkamp C, Scassola D, Helf C. 2024. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 36(2), 617–637."},"has_accepted_license":"1","department":[{"_id":"JuFi"}],"scopus_import":"1","date_created":"2023-10-22T22:01:16Z","publication":"Neural Computing and Applications","acknowledgement":"Open access funding provided by Università degli Studi di Trieste within the CRUI-CARE Agreement. Funding was provided by Austrian Science Fund (Grant No. F65), Horizon 2020 (Grant No. 754411) and Österreichische Forschungsförderungsgesellschaft.","ec_funded":1,"volume":36,"publication_identifier":{"issn":["0941-0643"],"eissn":["1433-3058"]},"quality_controlled":"1","arxiv":1,"external_id":{"pmid":["38187995"],"arxiv":["2203.04579"]},"fulldoi":"https://doi.org/10.1007/s00521-023-09033-7","file":[{"file_id":"17251","access_level":"open_access","content_type":"application/pdf","file_name":"2024_NeuralCompApplications_Cornalba.pdf","date_updated":"2024-07-16T08:08:54Z","checksum":"04573d8e74c6119b97c2ca0a984e19a1","file_size":4412285,"success":1,"creator":"dernst","relation":"main_file","date_created":"2024-07-16T08:08:54Z"}],"language":[{"iso":"eng"}],"date_published":"2024-01-01T00:00:00Z","day":"01","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"pmid":1,"page":"617-637","date_updated":"2025-04-23T07:39:14Z","title":"Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading","file_date_updated":"2024-07-16T08:08:54Z","abstract":[{"lang":"eng","text":"We investigate the potential of Multi-Objective, Deep Reinforcement Learning for stock and cryptocurrency single-asset trading: in particular, we consider a Multi-Objective algorithm which generalizes the reward functions and discount factor (i.e., these components are not specified a priori, but incorporated in the learning process). Firstly, using several important assets (BTCUSD, ETHUSDT, XRPUSDT, AAPL, SPY, NIFTY50), we verify the reward generalization property of the proposed Multi-Objective algorithm, and provide preliminary statistical evidence showing increased predictive stability over the corresponding Single-Objective strategy. Secondly, we show that the Multi-Objective algorithm has a clear edge over the corresponding Single-Objective strategy when the reward mechanism is sparse (i.e., when non-null feedback is infrequent over time). Finally, we discuss the generalization properties with respect to the discount factor. The entirety of our code is provided in open-source format."}],"publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1007/s00521-023-09033-7","type":"journal_article","project":[{"name":"Taming Complexity in Partial Differential Systems","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","grant_number":"F6504"},{"name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411"}],"status":"public","_id":"14451"},{"volume":33,"publication_identifier":{"issn":["0962-1083"],"eissn":["1365-294X"]},"OA_type":"hybrid","OA_place":"publisher","quality_controlled":"1","acknowledgement":"We would like to thank members of the Littorina team for their advice and feedback during this project. In particular, we thank Alan Le Moan, who inspired us to look at heterozygosity differences to identify inversions, and Katherine Hearn for helping with the PCA scripts. We thank Edinburgh Genomics for library preparation and sequencing. Sample collections, sequencing and data preparation were supported by the European Research Council (ERC-2015-AdG-693030- BARRIERS) and the Natural Environment Research Council (NE/P001610/1). The analysis was supported by the Swedish Research Council (vetenskaprådet; 2018-03695_VR) and the Portuguese Foundation for Science and Technology (Fundación para a Ciência e Tecnologia) through a research project (PTDC/BIA-EVL/1614/2021) and CEEC contract (2020.00275.CEECIND).","article_number":"e17160","scopus_import":"1","department":[{"_id":"NiBa"}],"date_created":"2023-10-29T23:01:17Z","publication":"Molecular Ecology","citation":{"short":"J. Reeve, R.K. Butlin, E.L. Koch, S. Stankowski, R. Faria, Molecular Ecology 33 (2024).","apa":"Reeve, J., Butlin, R. K., Koch, E. L., Stankowski, S., & Faria, R. (2024). Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. Wiley. https://doi.org/10.1111/mec.17160","ieee":"J. Reeve, R. K. Butlin, E. L. Koch, S. Stankowski, and R. Faria, “Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana),” Molecular Ecology, vol. 33, no. 24. Wiley, 2024.","chicago":"Reeve, James, Roger K. Butlin, Eva L. Koch, Sean Stankowski, and Rui Faria. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology. Wiley, 2024. https://doi.org/10.1111/mec.17160.","ista":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. 2024. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 33(24), e17160.","mla":"Reeve, James, et al. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology, vol. 33, no. 24, e17160, Wiley, 2024, doi:10.1111/mec.17160.","ama":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 2024;33(24). doi:10.1111/mec.17160"},"has_accepted_license":"1","month":"12","issue":"24","intvolume":" 33","oa_version":"Published Version","article_processing_charge":"Yes (in subscription journal)","year":"2024","oa":1,"ddc":["570"],"article_type":"original","publication_status":"published","author":[{"first_name":"James","full_name":"Reeve, James","last_name":"Reeve"},{"full_name":"Butlin, Roger K.","first_name":"Roger K.","last_name":"Butlin"},{"last_name":"Koch","full_name":"Koch, Eva L.","first_name":"Eva L."},{"last_name":"Stankowski","id":"43161670-5719-11EA-8025-FABC3DDC885E","full_name":"Stankowski, Sean","first_name":"Sean"},{"first_name":"Rui","full_name":"Faria, Rui","last_name":"Faria"}],"type":"journal_article","status":"public","_id":"14463","publisher":"Wiley","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1111/mec.17160","title":"Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana)","file_date_updated":"2025-01-09T07:52:12Z","abstract":[{"text":"Inversions are thought to play a key role in adaptation and speciation, suppressing recombination between diverging populations. Genes influencing adaptive traits cluster in inversions, and changes in inversion frequencies are associated with environmental differences. However, in many organisms, it is unclear if inversions are geographically and taxonomically widespread. The intertidal snail, Littorina saxatilis, is one such example. Strong associations between putative polymorphic inversions and phenotypic differences have been demonstrated between two ecotypes of L. saxatilis in Sweden and inferred elsewhere, but no direct evidence for inversion polymorphism currently exists across the species range. Using whole genome data from 107 snails, most inversion polymorphisms were found to be widespread across the species range. The frequencies of some inversion arrangements were significantly different among ecotypes, suggesting a parallel adaptive role. Many inversions were also polymorphic in the sister species, L. arcana, hinting at an ancient origin.","lang":"eng"}],"pmid":1,"date_updated":"2025-01-09T07:53:18Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_published":"2024-12-01T00:00:00Z","day":"01","external_id":{"isi":["001085119000001"],"pmid":["37843465"]},"file":[{"content_type":"application/pdf","file_name":"2024_MolecularEcology_Reeve.pdf","access_level":"open_access","file_id":"18785","date_created":"2025-01-09T07:52:12Z","relation":"main_file","success":1,"creator":"dernst","file_size":6228700,"date_updated":"2025-01-09T07:52:12Z","checksum":"686576036663f489c2d079df3079d126"}],"fulldoi":"https://doi.org/10.1111/mec.17160","isi":1,"language":[{"iso":"eng"}]},{"ddc":["570"],"publication_status":"published","article_type":"original","author":[{"first_name":"Michael","full_name":"Habig, Michael","last_name":"Habig"},{"last_name":"Grasse","full_name":"Grasse, Anna V","first_name":"Anna V","id":"406F989C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Müller","first_name":"Judith","full_name":"Müller, Judith"},{"full_name":"Stukenbrock, Eva H.","first_name":"Eva H.","last_name":"Stukenbrock"},{"full_name":"Leitner, Hanna","first_name":"Hanna","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7","last_name":"Leitner"},{"last_name":"Cremer","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia","full_name":"Cremer, Sylvia","orcid":"0000-0002-2193-3868"}],"oa_version":"Published Version","issue":"11","intvolume":" 121","APC_amount":"3040,36 EUR","month":"03","article_processing_charge":"Yes (in subscription journal)","year":"2024","oa":1,"publication":"Proceedings of the National Academy of Sciences of the United States of America","department":[{"_id":"SyCr"}],"scopus_import":"1","date_created":"2023-10-31T13:30:00Z","has_accepted_license":"1","corr_author":"1","citation":{"ista":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. 2024. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 121(11), e2316284121.","mla":"Habig, Michael, et al. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11, e2316284121, National Academy of Sciences, 2024, doi:10.1073/pnas.2316284121.","ama":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(11). doi:10.1073/pnas.2316284121","short":"M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","apa":"Habig, M., Grasse, A. V., Müller, J., Stukenbrock, E. H., Leitner, H., & Cremer, S. (2024). Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2316284121","ieee":"M. Habig, A. V. Grasse, J. Müller, E. H. Stukenbrock, H. Leitner, and S. Cremer, “Frequent horizontal chromosome transfer between asexual fungal insect pathogens,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11. National Academy of Sciences, 2024.","chicago":"Habig, Michael, Anna V Grasse, Judith Müller, Eva H. Stukenbrock, Hanna Leitner, and Sylvia Cremer. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2316284121."},"OA_type":"hybrid","quality_controlled":"1","OA_place":"publisher","ec_funded":1,"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"volume":121,"acknowledgement":"We thank Bernhardt Steinwender, Jorgen Eilenberg, and Nicolai V. Meyling for the fungal strains. We further thank Chengshu Wang for providing the short sequencing reads for M. guizhouense ARESF977 he used for his published genome assembly, and Kristian Ullrich for help in the bioinformatics analysis for methylation pattern in Nanopore reads, and the VBC and the Max Planck Society for the use of their sequencing centers. We thank Barbara Milutinović and Hinrich Schulenburg for discussion, and Tal Dagan and Jens Rolff for comments on a previous version of the manuscript. Fig. 1A was created with BioRender.com. This study received funding by the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (No. 771402; EPIDEMICSonCHIP) to S.C. and by the German Research Foundation (DFG grant HA9263/1-1) to M.H.","article_number":"e2316284121","day":"12","date_published":"2024-03-12T00:00:00Z","fulldoi":"https://doi.org/10.1073/pnas.2316284121","file":[{"date_updated":"2024-03-19T09:02:57Z","checksum":"f5e871db617b682edc71fcd08670dc81","file_size":5750361,"success":1,"creator":"dernst","date_created":"2024-03-19T09:02:57Z","relation":"main_file","file_id":"15124","access_level":"open_access","content_type":"application/pdf","file_name":"2024_PNAS_Habig.pdf"}],"isi":1,"language":[{"iso":"eng"}],"external_id":{"isi":["001207630200005"],"pmid":["38442176"]},"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"file_date_updated":"2024-03-19T09:02:57Z","abstract":[{"lang":"eng","text":"Entire chromosomes are typically only transmitted vertically from one generation to the next. The horizontal transfer of such chromosomes has long been considered improbable, yet gained recent support in several pathogenic fungi where it may affect the fitness or host specificity. To date, it is unknown how these transfers occur, how common they are and whether they can occur between different species. In this study, we show multiple independent instances of horizontal transfers of the same accessory chromosome between two distinct strains of the asexual entomopathogenic fungusMetarhizium robertsiiduring experimental co-infection of its insect host, the Argentine ant. Notably, only the one chromosome – but no other – was transferred from the donor to the recipient strain. The recipient strain, now harboring the accessory chromosome, exhibited a competitive advantage under certain host conditions. By phylogenetic analysis we further demonstrate that the same accessory chromosome was horizontally transferred in a natural environment betweenM. robertsiiand another congeneric insect pathogen,M. guizhouense. Hence horizontal chromosome transfer is not limited to the observed frequent events within species during experimental infections but also occurs naturally across species. The transferred accessory chromosome contains genes that might be involved in its preferential horizontal transfer, encoding putative histones and histone-modifying enzymes, but also putative virulence factors that may support its establishment. Our study reveals that both intra- and interspecies horizontal transfer of entire chromosomes is more frequent than previously assumed, likely representing a not uncommon mechanism for gene exchange.Significance StatementThe enormous success of bacterial pathogens has been attributed to their ability to exchange genetic material between one another. Similarly, in eukaryotes, horizontal transfer of genetic material allowed the spread of virulence factors across species. The horizontal transfer of whole chromosomes could be an important pathway for such exchange of genetic material, but little is known about the origin of transferable chromosomes and how frequently they are exchanged. Here, we show that the transfer of accessory chromosomes - chromosomes that are non-essential but may provide fitness benefits - is common during fungal co-infections and is even possible between distant pathogenic species, highlighting the importance of horizontal gene transfer via chromosome transfer also for the evolution and function of eukaryotic pathogens."}],"title":"Frequent horizontal chromosome transfer between asexual fungal insect pathogens","date_updated":"2025-08-05T13:30:51Z","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","pmid":1,"type":"journal_article","project":[{"grant_number":"771402","name":"Epidemics in ant societies on a chip","call_identifier":"H2020","_id":"2649B4DE-B435-11E9-9278-68D0E5697425"}],"_id":"14478","status":"public","doi":"10.1073/pnas.2316284121","publisher":"National Academy of Sciences","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"month":"02","intvolume":" 34","oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.1101/2023.10.26.564092","open_access":"1"}],"issue":"4","year":"2024","oa":1,"article_processing_charge":"No","author":[{"last_name":"Csata","full_name":"Csata, Eniko","first_name":"Eniko"},{"full_name":"Perez-Escudero, Alfonso","first_name":"Alfonso","last_name":"Perez-Escudero"},{"first_name":"Emmanuel","full_name":"Laury, Emmanuel","last_name":"Laury"},{"full_name":"Leitner, Hanna","first_name":"Hanna","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7","last_name":"Leitner"},{"first_name":"Gerard","full_name":"Latil, Gerard","last_name":"Latil"},{"full_name":"Heinze, Juerge","first_name":"Juerge","last_name":"Heinze"},{"last_name":"Simpson","full_name":"Simpson, Stephen","first_name":"Stephen"},{"id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia","full_name":"Cremer, Sylvia","orcid":"0000-0002-2193-3868","last_name":"Cremer"},{"last_name":"Dussutour","full_name":"Dussutour, Audrey","first_name":"Audrey"}],"article_type":"original","publication_status":"published","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"volume":34,"quality_controlled":"1","acknowledgement":"We are sincerely grateful to the referees for their valuable comments and suggestions, which helped us to improve the paper. We are thankful to Jorgen Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou, and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard, Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore, we thank Anna V. Grasse for help with the immune gene expression analyses. We thank Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by the CNRS.","date_created":"2023-10-31T13:30:20Z","scopus_import":"1","department":[{"_id":"SyCr"}],"publication":"Current Biology","citation":{"chicago":"Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology. Elsevier, 2024. https://doi.org/10.1016/j.cub.2024.01.017.","short":"E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S. Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.","ieee":"E. Csata et al., “Fungal infection alters collective nutritional intake of ant colonies,” Current Biology, vol. 34, no. 4. Elsevier, p. 902–909.e6, 2024.","apa":"Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J., … Dussutour, A. (2024). Fungal infection alters collective nutritional intake of ant colonies. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2024.01.017","mla":"Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6, doi:10.1016/j.cub.2024.01.017.","ama":"Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 2024;34(4):902-909.e6. doi:10.1016/j.cub.2024.01.017","ista":"Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 34(4), 902–909.e6."},"day":"26","date_published":"2024-02-26T00:00:00Z","external_id":{"isi":["001195884300001"],"pmid":["38307022"]},"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1016/j.cub.2024.01.017","isi":1,"_id":"14479","status":"public","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Elsevier","doi":"10.1016/j.cub.2024.01.017","title":"Fungal infection alters collective nutritional intake of ant colonies","abstract":[{"text":"In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6 Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12 but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16 How nutrition influences host-parasite interactions is not well understood, as studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23 We used the nutritional geometry framework24 to investigate the role of amino acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant, Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First, using 18 diets varying in AA:C composition, we established that the fungus performed best on the high-amino-acid diet 1:4. Second, we found that the fungus reached this optimal diet when given various diet pairings, revealing its ability to cope with nutritional challenges. Third, we showed that the optimal fungal diet reduced the lifespan of healthy ants when compared with a high-carbohydrate diet but had no effect on infected ants. Fourth, we revealed that infected ant colonies, given a choice between the optimal fungal diet and a high-carbohydrate diet, chose the optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling fungal infection from host immune response, we demonstrated that infected ants foraged on the optimal fungal diet in response to immune activation and not as a result of parasite manipulation. Therefore, we revealed that infected ant colonies chose a diet that is costly for survival in the long term but beneficial in the short term—a form of collective self-medication.","lang":"eng"}],"pmid":1,"date_updated":"2025-08-05T13:29:38Z","page":"902-909.e6"},{"date_created":"2023-11-16T12:36:51Z","department":[{"_id":"GradSch"}],"scopus_import":"1","publication":"Brain","citation":{"ieee":"R. Kaiyrzhanov et al., “Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders,” Brain, vol. 147, no. 4. Oxford University Press, pp. 1436–1456, 2024.","apa":"Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W., Godwin, A., … Maroofian, R. (2024). Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. Oxford University Press. https://doi.org/10.1093/brain/awad380","short":"R. Kaiyrzhanov, A. Rad, S.-J. Lin, A. Bertoli-Avella, W.W. Kallemeijn, A. Godwin, M.S. Zaki, K. Huang, T. Lau, C. Petree, S. Efthymiou, E. Ghayoor Karimiani, M. Hempel, E.A. Normand, S. Rudnik-Schöneborn, U.A. Schatz, M.P. Baggelaar, M. Ilyas, T. Sultan, J.R. Alvi, M. Ganieva, B. Fowler, R. Aanicai, G. Akay Tayfun, A. Al Saman, A. Alswaid, N. Amiri, N. Asilova, V. Shotelersuk, P. Yeetong, M. Azam, M. Babaei, G. Bahrami Monajemi, P. Mohammadi, S. Samie, S.H. Banu, J.P. Basto, F. Kortüm, M. Bauer, P. Bauer, C. Beetz, M. Garshasbi, A. Hameed Issa, W. Eyaid, H. Ahmed, N. Hashemi, K. Hassanpour, I. Herman, S. Ibrohimov, B.A. Abdul-Majeed, M. Imdad, M. Isrofilov, Q. Kaiyal, S. Khan, B. Kirmse, J. Koster, C.M. Lourenço, T. Mitani, O. Moldovan, D. Murphy, M. Najafi, D. Pehlivan, M.E. Rocha, V. Salpietro, M. Schmidts, A. Shalata, M. Mahroum, J.K. Talbeya, R.W. Taylor, D. Vazquez, A. Vetro, H.R. Waterham, M. Zaman, T.A. Schrader, W.K. Chung, R. Guerrini, J.R. Lupski, J. Gleeson, M. Suri, Y. Jamshidi, K.P. Bhatia, B. Vona, M. Schrader, M. Severino, M. Guille, E.W. Tate, G.K. Varshney, H. Houlden, R. Maroofian, Brain 147 (2024) 1436–1456.","chicago":"Kaiyrzhanov, Rauan, Aboulfazl Rad, Sheng-Jia Lin, Aida Bertoli-Avella, Wouter W Kallemeijn, Annie Godwin, Maha S Zaki, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” Brain. Oxford University Press, 2024. https://doi.org/10.1093/brain/awad380.","ista":"Kaiyrzhanov R, Rad A, Lin S-J, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Ghayoor Karimiani E, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Akay Tayfun G, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Bahrami Monajemi G, Mohammadi P, Samie S, Banu SH, Basto JP, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Hameed Issa A, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R. 2024. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. 147(4), 1436–1456.","ama":"Kaiyrzhanov R, Rad A, Lin S-J, et al. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. 2024;147(4):1436-1456. doi:10.1093/brain/awad380","mla":"Kaiyrzhanov, Rauan, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” Brain, vol. 147, no. 4, Oxford University Press, 2024, pp. 1436–56, doi:10.1093/brain/awad380."},"has_accepted_license":"1","extern":"1","publication_identifier":{"eissn":["1460-2156"],"issn":["0006-8950"]},"volume":147,"quality_controlled":"1","ddc":["570"],"author":[{"last_name":"Kaiyrzhanov","full_name":"Kaiyrzhanov, Rauan","first_name":"Rauan"},{"last_name":"Rad","full_name":"Rad, Aboulfazl","first_name":"Aboulfazl"},{"last_name":"Lin","first_name":"Sheng-Jia","full_name":"Lin, Sheng-Jia"},{"last_name":"Bertoli-Avella","full_name":"Bertoli-Avella, Aida","first_name":"Aida"},{"full_name":"Kallemeijn, Wouter W","first_name":"Wouter W","last_name":"Kallemeijn"},{"first_name":"Annie","full_name":"Godwin, Annie","last_name":"Godwin"},{"first_name":"Maha S","full_name":"Zaki, Maha S","last_name":"Zaki"},{"last_name":"Huang","first_name":"Kevin","full_name":"Huang, Kevin","orcid":"0000-0002-2512-7812","id":"3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3"},{"full_name":"Lau, Tracy","first_name":"Tracy","last_name":"Lau"},{"last_name":"Petree","full_name":"Petree, Cassidy","first_name":"Cassidy"},{"last_name":"Efthymiou","full_name":"Efthymiou, Stephanie","first_name":"Stephanie"},{"first_name":"Ehsan","full_name":"Ghayoor Karimiani, Ehsan","last_name":"Ghayoor Karimiani"},{"first_name":"Maja","full_name":"Hempel, Maja","last_name":"Hempel"},{"first_name":"Elizabeth A","full_name":"Normand, Elizabeth A","last_name":"Normand"},{"last_name":"Rudnik-Schöneborn","full_name":"Rudnik-Schöneborn, Sabine","first_name":"Sabine"},{"last_name":"Schatz","full_name":"Schatz, Ulrich A","first_name":"Ulrich A"},{"full_name":"Baggelaar, Marc P","first_name":"Marc P","last_name":"Baggelaar"},{"last_name":"Ilyas","full_name":"Ilyas, Muhammad","first_name":"Muhammad"},{"first_name":"Tipu","full_name":"Sultan, Tipu","last_name":"Sultan"},{"last_name":"Alvi","first_name":"Javeria Raza","full_name":"Alvi, Javeria Raza"},{"last_name":"Ganieva","full_name":"Ganieva, Manizha","first_name":"Manizha"},{"last_name":"Fowler","first_name":"Ben","full_name":"Fowler, Ben"},{"first_name":"Ruxandra","full_name":"Aanicai, Ruxandra","last_name":"Aanicai"},{"last_name":"Akay Tayfun","first_name":"Gulsen","full_name":"Akay Tayfun, Gulsen"},{"last_name":"Al Saman","full_name":"Al Saman, Abdulaziz","first_name":"Abdulaziz"},{"last_name":"Alswaid","full_name":"Alswaid, Abdulrahman","first_name":"Abdulrahman"},{"first_name":"Nafise","full_name":"Amiri, Nafise","last_name":"Amiri"},{"last_name":"Asilova","full_name":"Asilova, Nilufar","first_name":"Nilufar"},{"last_name":"Shotelersuk","full_name":"Shotelersuk, Vorasuk","first_name":"Vorasuk"},{"full_name":"Yeetong, Patra","first_name":"Patra","last_name":"Yeetong"},{"full_name":"Azam, Matloob","first_name":"Matloob","last_name":"Azam"},{"first_name":"Meisam","full_name":"Babaei, Meisam","last_name":"Babaei"},{"last_name":"Bahrami Monajemi","first_name":"Gholamreza","full_name":"Bahrami Monajemi, Gholamreza"},{"last_name":"Mohammadi","first_name":"Pouria","full_name":"Mohammadi, Pouria"},{"full_name":"Samie, Saeed","first_name":"Saeed","last_name":"Samie"},{"first_name":"Selina Husna","full_name":"Banu, Selina Husna","last_name":"Banu"},{"first_name":"Jorge Pinto","full_name":"Basto, Jorge Pinto","last_name":"Basto"},{"last_name":"Kortüm","first_name":"Fanny","full_name":"Kortüm, Fanny"},{"last_name":"Bauer","full_name":"Bauer, Mislen","first_name":"Mislen"},{"last_name":"Bauer","first_name":"Peter","full_name":"Bauer, Peter"},{"first_name":"Christian","full_name":"Beetz, Christian","last_name":"Beetz"},{"full_name":"Garshasbi, Masoud","first_name":"Masoud","last_name":"Garshasbi"},{"last_name":"Hameed Issa","first_name":"Awatif","full_name":"Hameed Issa, Awatif"},{"first_name":"Wafaa","full_name":"Eyaid, Wafaa","last_name":"Eyaid"},{"last_name":"Ahmed","full_name":"Ahmed, Hind","first_name":"Hind"},{"last_name":"Hashemi","full_name":"Hashemi, Narges","first_name":"Narges"},{"last_name":"Hassanpour","full_name":"Hassanpour, Kazem","first_name":"Kazem"},{"first_name":"Isabella","full_name":"Herman, Isabella","last_name":"Herman"},{"first_name":"Sherozjon","full_name":"Ibrohimov, Sherozjon","last_name":"Ibrohimov"},{"last_name":"Abdul-Majeed","first_name":"Ban A","full_name":"Abdul-Majeed, Ban A"},{"full_name":"Imdad, Maria","first_name":"Maria","last_name":"Imdad"},{"last_name":"Isrofilov","first_name":"Maksudjon","full_name":"Isrofilov, Maksudjon"},{"last_name":"Kaiyal","full_name":"Kaiyal, Qassem","first_name":"Qassem"},{"first_name":"Suliman","full_name":"Khan, Suliman","last_name":"Khan"},{"last_name":"Kirmse","full_name":"Kirmse, Brian","first_name":"Brian"},{"first_name":"Janet","full_name":"Koster, Janet","last_name":"Koster"},{"last_name":"Lourenço","first_name":"Charles Marques","full_name":"Lourenço, Charles Marques"},{"last_name":"Mitani","first_name":"Tadahiro","full_name":"Mitani, Tadahiro"},{"first_name":"Oana","full_name":"Moldovan, Oana","last_name":"Moldovan"},{"last_name":"Murphy","first_name":"David","full_name":"Murphy, David"},{"last_name":"Najafi","full_name":"Najafi, Maryam","first_name":"Maryam"},{"last_name":"Pehlivan","first_name":"Davut","full_name":"Pehlivan, Davut"},{"first_name":"Maria Eugenia","full_name":"Rocha, Maria Eugenia","last_name":"Rocha"},{"last_name":"Salpietro","first_name":"Vincenzo","full_name":"Salpietro, Vincenzo"},{"full_name":"Schmidts, Miriam","first_name":"Miriam","last_name":"Schmidts"},{"full_name":"Shalata, Adel","first_name":"Adel","last_name":"Shalata"},{"last_name":"Mahroum","first_name":"Mohammad","full_name":"Mahroum, Mohammad"},{"last_name":"Talbeya","full_name":"Talbeya, Jawabreh Kassem","first_name":"Jawabreh Kassem"},{"last_name":"Taylor","first_name":"Robert W","full_name":"Taylor, Robert W"},{"last_name":"Vazquez","first_name":"Dayana","full_name":"Vazquez, Dayana"},{"full_name":"Vetro, Annalisa","first_name":"Annalisa","last_name":"Vetro"},{"last_name":"Waterham","first_name":"Hans R","full_name":"Waterham, Hans R"},{"first_name":"Mashaya","full_name":"Zaman, Mashaya","last_name":"Zaman"},{"full_name":"Schrader, Tina A","first_name":"Tina A","last_name":"Schrader"},{"first_name":"Wendy K","full_name":"Chung, Wendy K","last_name":"Chung"},{"first_name":"Renzo","full_name":"Guerrini, Renzo","last_name":"Guerrini"},{"first_name":"James R","full_name":"Lupski, James R","last_name":"Lupski"},{"last_name":"Gleeson","first_name":"Joseph","full_name":"Gleeson, Joseph"},{"last_name":"Suri","full_name":"Suri, Mohnish","first_name":"Mohnish"},{"first_name":"Yalda","full_name":"Jamshidi, Yalda","last_name":"Jamshidi"},{"full_name":"Bhatia, Kailash P","first_name":"Kailash P","last_name":"Bhatia"},{"full_name":"Vona, Barbara","first_name":"Barbara","last_name":"Vona"},{"full_name":"Schrader, Michael","first_name":"Michael","last_name":"Schrader"},{"full_name":"Severino, Mariasavina","first_name":"Mariasavina","last_name":"Severino"},{"last_name":"Guille","full_name":"Guille, Matthew","first_name":"Matthew"},{"full_name":"Tate, Edward W","first_name":"Edward W","last_name":"Tate"},{"first_name":"Gaurav K","full_name":"Varshney, Gaurav K","last_name":"Varshney"},{"last_name":"Houlden","first_name":"Henry","full_name":"Houlden, Henry"},{"full_name":"Maroofian, Reza","first_name":"Reza","last_name":"Maroofian"}],"article_type":"original","publication_status":"published","month":"04","issue":"4","oa_version":"Submitted Version","intvolume":" 147","oa":1,"year":"2024","article_processing_charge":"No","title":"Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders","abstract":[{"text":"The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed, plays a role in the acylation of lipids and proteins, and regulates the N-myristoylation of proteins via N-myristoyltransferase enzymes (NMTs). However, its precise function in cells is still unclear, as is the consequence of ACBD6 defects on human pathophysiology. Utilizing exome sequencing and extensive international data sharing efforts, we identified 45 affected individuals from 28 unrelated families (consanguinity 93%) with bi-allelic pathogenic, predominantly loss-of-function (18/20) variants in ACBD6. We generated zebrafish and Xenopus tropicalis acbd6 knockouts by CRISPR/Cas9 and characterized the role of ACBD6 on protein N-myristoylation with YnMyr chemical proteomics in the model organisms and human cells, with the latter also being subjected further to ACBD6 peroxisomal localization studies. The affected individuals (23 males and 22 females), with ages ranging from 1 to 50 years old, typically present with a complex and progressive disease involving moderate-to-severe global developmental delay/intellectual disability (100%) with significant expressive language impairment (98%), movement disorders (97%), facial dysmorphism (95%), and mild cerebellar ataxia (85%) associated with gait impairment (94%), limb spasticity/hypertonia (76%), oculomotor (71%) and behavioural abnormalities (65%), overweight (59%), microcephaly (39%) and epilepsy (33%). The most conspicuous and common movement disorder was dystonia (94%), frequently leading to early-onset progressive postural deformities (97%), limb dystonia (55%), and cervical dystonia (31%). A jerky tremor in the upper limbs (63%), a mild head tremor (59%), parkinsonism/hypokinesia developing with advancing age (32%), and simple motor and vocal tics were among other frequent movement disorders. Midline brain malformations including corpus callosum abnormalities (70%), hypoplasia/agenesis of the anterior commissure (66%), short midbrain and small inferior cerebellar vermis (38% each), as well as hypertrophy of the clava (24%) were common neuroimaging findings. acbd6-deficient zebrafish and Xenopus models effectively recapitulated many clinical phenotypes reported in patients including movement disorders, progressive neuromotor impairment, seizures, microcephaly, craniofacial dysmorphism, and midbrain defects accompanied by developmental delay with increased mortality over time. Unlike ACBD5, ACBD6 did not show a peroxisomal localisation and ACBD6-deficiency was not associated with altered peroxisomal parameters in patient fibroblasts. Significant differences in YnMyr-labelling were observed for 68 co- and 18 post-translationally N-myristoylated proteins in patient-derived fibroblasts. N-Myristoylation was similarly affected in acbd6-deficient zebrafish and Xenopus tropicalis models, including Fus, Marcks, and Chchd-related proteins implicated in neurological diseases. The present study provides evidence that bi-allelic pathogenic variants in ACBD6 lead to a distinct neurodevelopmental syndrome accompanied by complex and progressive cognitive and movement disorders.","lang":"eng"}],"file_date_updated":"2024-07-16T08:22:13Z","pmid":1,"page":"1436-1456","date_updated":"2024-07-16T08:23:24Z","_id":"14543","status":"public","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Oxford University Press","doi":"10.1093/brain/awad380","day":"01","date_published":"2024-04-01T00:00:00Z","external_id":{"pmid":["37951597"]},"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1093/brain/awad380","file":[{"checksum":"0ee7a8ab9300225d60968f7a3e3cfa0d","date_updated":"2024-07-16T08:22:13Z","file_size":2641456,"creator":"dernst","success":1,"date_created":"2024-07-16T08:22:13Z","relation":"main_file","file_id":"17254","access_level":"open_access","content_type":"application/pdf","file_name":"2024_Brain_Kaiyrzhanov.pdf"}],"keyword":["Neurology (clinical)"],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"}},{"_id":"14652","status":"public","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publisher":"Elsevier","doi":"10.1016/j.physb.2023.415539","title":"Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys","abstract":[{"text":"In order to demonstrate the stability of newly proposed iridium-based Ir2Cr(In,Sn) and IrRhCr(In,Sn) heusler alloys, we present ab-initio analysis of these alloys by examining various properties to prove their stability. The stability of these alloys can be inferred from different cohesive and formation energies as well as positive phonon frequencies. Their electronic structure results indicate that they are semi-metals in nature. The magnetic moments are computed using the Slater-Pauling formula and exhibit a high value, with the Cr atom contributing the most in all alloys. Mulliken’s charge analysis results show that our alloys contain a range of linkages, mainly ionic and covalent ones. The ductility and mechanical stability of these alloys are confirmed by elastic constants viz. Poisson’s ratio, Pugh’s ratio, and many different types of elastic moduli.","lang":"eng"}],"date_updated":"2025-09-04T11:29:46Z","day":"01","date_published":"2024-02-01T00:00:00Z","external_id":{"isi":["001127429000001"]},"language":[{"iso":"eng"}],"isi":1,"fulldoi":"https://doi.org/10.1016/j.physb.2023.415539","publication_identifier":{"issn":["0921-4526"]},"volume":674,"quality_controlled":"1","article_number":"415539","date_created":"2023-12-10T23:00:56Z","department":[{"_id":"MaIb"}],"scopus_import":"1","publication":"Physica B: Condensed Matter","citation":{"ama":"Gupta SL, Singh S, Kumar S, et al. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 2024;674(2). doi:10.1016/j.physb.2023.415539","mla":"Gupta, Shyam Lal, et al. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter, vol. 674, no. 2, 415539, Elsevier, 2024, doi:10.1016/j.physb.2023.415539.","ista":"Gupta SL, Singh S, Kumar S, Anupam U, Thakur SS, Kumar A, Panwar S, Diwaker D. 2024. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 674(2), 415539.","chicago":"Gupta, Shyam Lal, Saurabh Singh, Sumit Kumar, Unknown Anupam, Samjeet Singh Thakur, Ashish Kumar, Sanjay Panwar, and D. Diwaker. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter. Elsevier, 2024. https://doi.org/10.1016/j.physb.2023.415539.","ieee":"S. L. Gupta et al., “Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys,” Physica B: Condensed Matter, vol. 674, no. 2. Elsevier, 2024.","apa":"Gupta, S. L., Singh, S., Kumar, S., Anupam, U., Thakur, S. S., Kumar, A., … Diwaker, D. (2024). Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. Elsevier. https://doi.org/10.1016/j.physb.2023.415539","short":"S.L. Gupta, S. Singh, S. Kumar, U. Anupam, S.S. Thakur, A. Kumar, S. Panwar, D. Diwaker, Physica B: Condensed Matter 674 (2024)."},"month":"02","issue":"2","oa_version":"None","intvolume":" 674","year":"2024","article_processing_charge":"No","author":[{"last_name":"Gupta","full_name":"Gupta, Shyam Lal","first_name":"Shyam Lal"},{"orcid":"0000-0003-2209-5269","full_name":"Singh, Saurabh","first_name":"Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","last_name":"Singh"},{"first_name":"Sumit","full_name":"Kumar, Sumit","last_name":"Kumar"},{"last_name":"Anupam","first_name":"Unknown","full_name":"Anupam, Unknown"},{"first_name":"Samjeet Singh","full_name":"Thakur, Samjeet Singh","last_name":"Thakur"},{"last_name":"Kumar","first_name":"Ashish","full_name":"Kumar, Ashish"},{"full_name":"Panwar, Sanjay","first_name":"Sanjay","last_name":"Panwar"},{"first_name":"D.","full_name":"Diwaker, D.","last_name":"Diwaker"}],"article_type":"original","publication_status":"published"},{"date_updated":"2025-09-04T11:30:59Z","abstract":[{"text":"Mass spectrometry imaging (MSI) is a powerful analytical technique for the two-dimensional (2D) localization of chemicals on surfaces. Conventional MSI experiments require to predefine the surface of interest based on photographic or microscopic images. Typically, these boundaries can no longer be changed or adjusted once the experiment has been started. In terms of a more interactive approach we recently developed a pen-like ionization interface which is directly connected to the mass spectrometer. The device allows the user to ionize chemicals by desorption electrospray ionization (DESI) and to freely move the interface over a surface of interest. A mini camera, which is mounted on the tip of the pen, magnifies the desorption area and enables a simple positioning of the pen. The combination of optical data from the camera module and chemical data obtained by mass analysis facilitates a novel type of imaging experiment: interactive mass spectrometry imaging (IMSI). For this application, we present a novel approach for a robust, optical flow-based motion detection. While the live video stream from the camera is used to track the pen's motion across the surface a post-acquisition algorithm correlates the coordinates of the pen trajectory with respective mass spectra obtained from a simultaneous mass spectrometric data acquisition. This algorithm is no longer dependent on a single, manually applied optical marker on the sample surface, which has to be visible on all video frames throughout the analysis. The advanced DESI-IMSI method was successfully tested on inkjet-printed letters as well as mouse brain tissue samples. Validation of the results was done by comparing DESI-IMSI with standard DESI-MSI data.","lang":"eng"}],"file_date_updated":"2024-07-16T08:27:34Z","title":"Advanced motion tracking for interactive mass spectrometry imaging (IMSI)","doi":"10.1016/j.ijms.2023.117168","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publisher":"Elsevier","_id":"14653","status":"public","type":"journal_article","language":[{"iso":"eng"}],"file":[{"relation":"main_file","date_created":"2024-07-16T08:27:34Z","creator":"dernst","success":1,"file_size":3003139,"checksum":"6c5eb6dc07af70a59251d2c6fed38894","date_updated":"2024-07-16T08:27:34Z","file_name":"2024_IJMS_Kluibenschedl.pdf","content_type":"application/pdf","access_level":"open_access","file_id":"17256"}],"fulldoi":"https://doi.org/10.1016/j.ijms.2023.117168","isi":1,"external_id":{"isi":["001125054400001"]},"day":"01","date_published":"2024-01-01T00:00:00Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"has_accepted_license":"1","citation":{"mla":"Kluibenschedl, Florian, et al. “Advanced Motion Tracking for Interactive Mass Spectrometry Imaging (IMSI).” International Journal of Mass Spectrometry, vol. 495, 117168, Elsevier, 2024, doi:10.1016/j.ijms.2023.117168.","ama":"Kluibenschedl F, Ploner A, Meisenbichler C, Konrat R, Müller T. Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. 2024;495. doi:10.1016/j.ijms.2023.117168","ista":"Kluibenschedl F, Ploner A, Meisenbichler C, Konrat R, Müller T. 2024. Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. 495, 117168.","chicago":"Kluibenschedl, Florian, Anna Ploner, Christina Meisenbichler, Robert Konrat, and Thomas Müller. “Advanced Motion Tracking for Interactive Mass Spectrometry Imaging (IMSI).” International Journal of Mass Spectrometry. Elsevier, 2024. https://doi.org/10.1016/j.ijms.2023.117168.","short":"F. Kluibenschedl, A. Ploner, C. Meisenbichler, R. Konrat, T. Müller, International Journal of Mass Spectrometry 495 (2024).","apa":"Kluibenschedl, F., Ploner, A., Meisenbichler, C., Konrat, R., & Müller, T. (2024). Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. Elsevier. https://doi.org/10.1016/j.ijms.2023.117168","ieee":"F. Kluibenschedl, A. Ploner, C. Meisenbichler, R. Konrat, and T. Müller, “Advanced motion tracking for interactive mass spectrometry imaging (IMSI),” International Journal of Mass Spectrometry, vol. 495. Elsevier, 2024."},"publication":"International Journal of Mass Spectrometry","date_created":"2023-12-10T23:00:57Z","scopus_import":"1","department":[{"_id":"GradSch"}],"article_number":"117168","acknowledgement":"We would like to thank Marco Sealey Cardona, PhD for help with the mouse brain samples and acknowledge the financial support by 1669 Förderkreis of the University of Innsbruck, Austria Wirtschaftsservice (AWS), D. Swarovski KG and Tyrolean Science Fund (TWF).","quality_controlled":"1","volume":495,"publication_identifier":{"issn":["1387-3806"]},"author":[{"first_name":"Florian","full_name":"Kluibenschedl, Florian","id":"7499e70e-eb2c-11ec-b98b-f925648bc9d9","last_name":"Kluibenschedl"},{"full_name":"Ploner, Anna","first_name":"Anna","last_name":"Ploner"},{"last_name":"Meisenbichler","first_name":"Christina","full_name":"Meisenbichler, Christina"},{"full_name":"Konrat, Robert","first_name":"Robert","last_name":"Konrat"},{"first_name":"Thomas","full_name":"Müller, Thomas","last_name":"Müller"}],"article_type":"original","publication_status":"published","ddc":["540"],"oa":1,"year":"2024","article_processing_charge":"Yes (in subscription journal)","intvolume":" 495","oa_version":"Published Version","month":"01"},{"type":"journal_article","_id":"14660","status":"public","doi":"10.1112/blms.12965","publisher":"London Mathematical Society","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file_date_updated":"2024-07-16T10:35:10Z","abstract":[{"text":"The classical Steinitz theorem states that if the origin belongs to the interior of the convex hull of a set 𝑆⊂ℝ𝑑, then there are at most 2𝑑 points of 𝑆 whose convex hull contains the origin in the interior. Bárány, Katchalski,and Pach proved the following quantitative version of Steinitz’s theorem. Let 𝑄 be a convex polytope in ℝ𝑑 containing the standard Euclidean unit ball 𝐁𝑑. Then there exist at most 2𝑑 vertices of 𝑄 whose convex hull 𝑄′ satisfies 𝑟𝐁𝑑⊂𝑄′ with 𝑟⩾𝑑−2𝑑. They conjectured that 𝑟⩾𝑐𝑑−1∕2 holds with a universal constant 𝑐>0. We prove 𝑟⩾15𝑑2, the first polynomial lower bound on 𝑟. Furthermore, we show that 𝑟 is not greater than 2/√𝑑.","lang":"eng"}],"title":"Quantitative Steinitz theorem: A polynomial bound","page":"796-802","date_updated":"2025-09-04T11:31:49Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_published":"2024-02-01T00:00:00Z","day":"01","fulldoi":"https://doi.org/10.1112/blms.12965","file":[{"checksum":"30ea0694757bc668cf7cd15ae357b35e","date_updated":"2024-07-16T10:35:10Z","file_size":111756,"success":1,"creator":"dernst","date_created":"2024-07-16T10:35:10Z","relation":"main_file","file_id":"17259","access_level":"open_access","content_type":"application/pdf","file_name":"2024_BulletinLondonMathSoc_Ivanov.pdf"}],"isi":1,"language":[{"iso":"eng"}],"external_id":{"arxiv":["2212.04308"],"isi":["001113277100001"]},"arxiv":1,"quality_controlled":"1","volume":56,"publication_identifier":{"eissn":["1469-2120"],"issn":["0024-6093"]},"acknowledgement":"M.N. was supported by the János Bolyai Scholarship of the Hungarian Academy of Sciences aswell as the National Research, Development and Innovation Fund (NRDI) grants K119670 andK131529, and the ÚNKP-22-5 New National Excellence Program of the Ministry for Innovationand Technology from the source of the NRDI as well as the ELTE TKP 2021-NKTA-62 fundingscheme","publication":"Bulletin of the London Mathematical Society","department":[{"_id":"UlWa"}],"scopus_import":"1","date_created":"2023-12-10T23:00:58Z","has_accepted_license":"1","corr_author":"1","citation":{"short":"G. Ivanov, M. Naszódi, Bulletin of the London Mathematical Society 56 (2024) 796–802.","apa":"Ivanov, G., & Naszódi, M. (2024). Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. London Mathematical Society. https://doi.org/10.1112/blms.12965","ieee":"G. Ivanov and M. Naszódi, “Quantitative Steinitz theorem: A polynomial bound,” Bulletin of the London Mathematical Society, vol. 56, no. 2. London Mathematical Society, pp. 796–802, 2024.","chicago":"Ivanov, Grigory, and Márton Naszódi. “Quantitative Steinitz Theorem: A Polynomial Bound.” Bulletin of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/blms.12965.","ista":"Ivanov G, Naszódi M. 2024. Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. 56(2), 796–802.","ama":"Ivanov G, Naszódi M. Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. 2024;56(2):796-802. doi:10.1112/blms.12965","mla":"Ivanov, Grigory, and Márton Naszódi. “Quantitative Steinitz Theorem: A Polynomial Bound.” Bulletin of the London Mathematical Society, vol. 56, no. 2, London Mathematical Society, 2024, pp. 796–802, doi:10.1112/blms.12965."},"oa_version":"Published Version","issue":"2","intvolume":" 56","month":"02","article_processing_charge":"Yes (via OA deal)","oa":1,"year":"2024","ddc":["510"],"article_type":"original","publication_status":"published","author":[{"first_name":"Grigory","full_name":"Ivanov, Grigory","id":"87744F66-5C6F-11EA-AFE0-D16B3DDC885E","last_name":"Ivanov"},{"last_name":"Naszódi","full_name":"Naszódi, Márton","first_name":"Márton"}]},{"abstract":[{"text":"We derive lower bounds on the maximal rates for multiple packings in high-dimensional Euclidean spaces. For any N > 0 and L ∈ Z ≥2 , a multiple packing is a set C of points in R n such that any point in R n lies in the intersection of at most L - 1 balls of radius √ nN around points in C . This is a natural generalization of the sphere packing problem. We study the multiple packing problem for both bounded point sets whose points have norm at most √ nP for some constant P > 0, and unbounded point sets whose points are allowed to be anywhere in R n . Given a well-known connection with coding theory, multiple packings can be viewed as the Euclidean analog of list-decodable codes, which are well-studied over finite fields. We derive the best known lower bounds on the optimal multiple packing density. This is accomplished by establishing an inequality which relates the list-decoding error exponent for additive white Gaussian noise channels, a quantity of average-case nature, to the list-decoding radius, a quantity of worst-case nature. We also derive novel bounds on the list-decoding error exponent for infinite constellations and closed-form expressions for the list-decoding error exponents for the power-constrained AWGN channel, which may be of independent interest beyond multiple packing.","lang":"eng"}],"title":"Multiple packing: Lower bounds via error exponents","date_updated":"2025-09-04T11:32:49Z","page":"1008-1039","type":"journal_article","_id":"14665","status":"public","doi":"10.1109/TIT.2023.3334032","publisher":"IEEE","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_published":"2024-02-01T00:00:00Z","day":"01","fulldoi":"https://doi.org/10.1109/TIT.2023.3334032","isi":1,"language":[{"iso":"eng"}],"external_id":{"isi":["001166812100008"],"arxiv":["2211.04408"]},"publication":"IEEE Transactions on Information Theory","scopus_import":"1","department":[{"_id":"MaMo"}],"date_created":"2023-12-10T23:01:00Z","corr_author":"1","citation":{"chicago":"Zhang, Yihan, and Shashank Vatedka. “Multiple Packing: Lower Bounds via Error Exponents.” IEEE Transactions on Information Theory. IEEE, 2024. https://doi.org/10.1109/TIT.2023.3334032.","short":"Y. Zhang, S. Vatedka, IEEE Transactions on Information Theory 70 (2024) 1008–1039.","ieee":"Y. Zhang and S. Vatedka, “Multiple packing: Lower bounds via error exponents,” IEEE Transactions on Information Theory, vol. 70, no. 2. IEEE, pp. 1008–1039, 2024.","apa":"Zhang, Y., & Vatedka, S. (2024). Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. IEEE. https://doi.org/10.1109/TIT.2023.3334032","ama":"Zhang Y, Vatedka S. Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. 2024;70(2):1008-1039. doi:10.1109/TIT.2023.3334032","mla":"Zhang, Yihan, and Shashank Vatedka. “Multiple Packing: Lower Bounds via Error Exponents.” IEEE Transactions on Information Theory, vol. 70, no. 2, IEEE, 2024, pp. 1008–39, doi:10.1109/TIT.2023.3334032.","ista":"Zhang Y, Vatedka S. 2024. Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. 70(2), 1008–1039."},"arxiv":1,"quality_controlled":"1","publication_identifier":{"issn":["0018-9448"],"eissn":["1557-9654"]},"volume":70,"acknowledgement":"The work of Yihan Zhang was supported by the European Union’s Horizon 2020 Research and Innovation Programme under Grant 682203-ERC-[Inf-Speed-Tradeoff]. The work of Shashank Vatedka was supported in part by the Core Research Grant from the Science and\r\nEngineering Research Board, India, under Grant CRG/2022/004464; and in\r\npart by the Department of Science and Technology (DST), India, under Grant\r\nDST/INT/RUS/RSF/P-41/2020 (TPN No. 65025).","publication_status":"published","article_type":"original","author":[{"first_name":"Yihan","full_name":"Zhang, Yihan","orcid":"0000-0002-6465-6258","id":"2ce5da42-b2ea-11eb-bba5-9f264e9d002c","last_name":"Zhang"},{"last_name":"Vatedka","first_name":"Shashank","full_name":"Vatedka, Shashank"}],"issue":"2","intvolume":" 70","oa_version":"Preprint","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2211.04408"}],"month":"02","article_processing_charge":"No","year":"2024","oa":1},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Neuroscience"],"external_id":{"pmid":["38070137"]},"fulldoi":"https://doi.org/10.1016/j.xpro.2023.102771","file":[{"success":1,"creator":"dernst","relation":"main_file","date_created":"2024-07-16T11:50:03Z","date_updated":"2024-07-16T11:50:03Z","checksum":"3f0ee62e04bf5a44b45b035662826e95","file_size":8871807,"content_type":"application/pdf","file_name":"2024_STARProtoc_Amberg.pdf","file_id":"17260","access_level":"open_access"}],"language":[{"iso":"eng"}],"date_published":"2024-03-15T00:00:00Z","day":"15","publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1016/j.xpro.2023.102771","project":[{"grant_number":"T01031","name":"Role of Eed in neural stem cell lineage progression","call_identifier":"FWF","_id":"268F8446-B435-11E9-9278-68D0E5697425"},{"name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411"},{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F7805"},{"_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","call_identifier":"H2020","grant_number":"725780"}],"type":"journal_article","_id":"14683","status":"public","pmid":1,"date_updated":"2025-04-15T08:23:06Z","title":"Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry","file_date_updated":"2024-07-16T11:50:03Z","abstract":[{"text":"Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice and high-resolution phenotyping at the individual cell level. Here, we present a protocol for isolating MADM-labeled cells with high yield for downstream molecular analyses using fluorescence-activated cell sorting (FACS). We describe steps for generating MADM-labeled mice, perfusion, single-cell suspension, and debris removal. We then detail procedures for cell sorting by FACS and downstream analysis. This protocol is suitable for embryonic to adult mice.\r\nFor complete details on the use and execution of this protocol, please refer to Contreras et al. (2021).1","lang":"eng"}],"article_processing_charge":"Yes (in subscription journal)","year":"2024","oa":1,"month":"03","issue":"1","oa_version":"Published Version","intvolume":" 5","article_type":"review","publication_status":"published","author":[{"last_name":"Amberg","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","first_name":"Nicole","orcid":"0000-0002-3183-8207","full_name":"Amberg, Nicole"},{"id":"471195F6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8457-2572","full_name":"Cheung, Giselle T","first_name":"Giselle T","last_name":"Cheung"},{"last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061"}],"ddc":["570"],"acknowledgement":"This research was supported by the Scientific Service Units (SSU) at IST Austria through resources provided by the Imaging & Optics Facility (IOF) and Preclinical Facilities (PCF). N.A. received support from FWF Firnberg-Programme (T 1031). G.C. received support from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 754411 as an ISTplus postdoctoral fellow. This work was also supported by IST Austria institutional funds, FWF SFB F78 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 725780 LinPro) to S.H.","article_number":"102771","ec_funded":1,"volume":5,"publication_identifier":{"issn":["2666-1667"]},"quality_controlled":"1","corr_author":"1","citation":{"ieee":"N. Amberg, G. T. Cheung, and S. Hippenmeyer, “Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry,” STAR Protocols, vol. 5, no. 1. Elsevier, 2024.","apa":"Amberg, N., Cheung, G. T., & Hippenmeyer, S. (2024). Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. Elsevier. https://doi.org/10.1016/j.xpro.2023.102771","short":"N. Amberg, G.T. Cheung, S. Hippenmeyer, STAR Protocols 5 (2024).","chicago":"Amberg, Nicole, Giselle T Cheung, and Simon Hippenmeyer. “Protocol for Sorting Cells from Mouse Brains Labeled with Mosaic Analysis with Double Markers by Flow Cytometry.” STAR Protocols. Elsevier, 2024. https://doi.org/10.1016/j.xpro.2023.102771.","ista":"Amberg N, Cheung GT, Hippenmeyer S. 2024. Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. 5(1), 102771.","ama":"Amberg N, Cheung GT, Hippenmeyer S. Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. 2024;5(1). doi:10.1016/j.xpro.2023.102771","mla":"Amberg, Nicole, et al. “Protocol for Sorting Cells from Mouse Brains Labeled with Mosaic Analysis with Double Markers by Flow Cytometry.” STAR Protocols, vol. 5, no. 1, 102771, Elsevier, 2024, doi:10.1016/j.xpro.2023.102771."},"has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"scopus_import":"1","department":[{"_id":"SiHi"}],"date_created":"2023-12-13T11:48:05Z","publication":"STAR Protocols"},{"quality_controlled":"1","volume":248,"publication_identifier":{"issn":["1359-6640"],"eissn":["1364-5498"]},"citation":{"chicago":"Archer, Lynden A., Peter G. Bruce, Ernesto J. Calvo, Daniel Dewar, James H. J. Ellison, Stefan Alexander Freunberger, Xiangwen Gao, et al. “Towards Practical Metal–Oxygen Batteries: General Discussion.” Faraday Discussions. Royal Society of Chemistry, 2024. https://doi.org/10.1039/d3fd90062b.","short":"L.A. Archer, P.G. Bruce, E.J. Calvo, D. Dewar, J.H.J. Ellison, S.A. Freunberger, X. Gao, L.J. Hardwick, G. Horwitz, J. Janek, L.R. Johnson, J.W. Jordan, S. Matsuda, S. Menkin, S. Mondal, Q. Qiu, T. Samarakoon, I. Temprano, K. Uosaki, G. Vailaya, E.D. Wachsman, Y. Wu, S. Ye, Faraday Discussions 248 (2024) 392–411.","ieee":"L. A. Archer et al., “Towards practical metal–oxygen batteries: General discussion,” Faraday Discussions, vol. 248. Royal Society of Chemistry, pp. 392–411, 2024.","apa":"Archer, L. A., Bruce, P. G., Calvo, E. J., Dewar, D., Ellison, J. H. J., Freunberger, S. A., … Ye, S. (2024). Towards practical metal–oxygen batteries: General discussion. Faraday Discussions. Royal Society of Chemistry. https://doi.org/10.1039/d3fd90062b","mla":"Archer, Lynden A., et al. “Towards Practical Metal–Oxygen Batteries: General Discussion.” Faraday Discussions, vol. 248, Royal Society of Chemistry, 2024, pp. 392–411, doi:10.1039/d3fd90062b.","ama":"Archer LA, Bruce PG, Calvo EJ, et al. Towards practical metal–oxygen batteries: General discussion. Faraday Discussions. 2024;248:392-411. doi:10.1039/d3fd90062b","ista":"Archer LA, Bruce PG, Calvo EJ, Dewar D, Ellison JHJ, Freunberger SA, Gao X, Hardwick LJ, Horwitz G, Janek J, Johnson LR, Jordan JW, Matsuda S, Menkin S, Mondal S, Qiu Q, Samarakoon T, Temprano I, Uosaki K, Vailaya G, Wachsman ED, Wu Y, Ye S. 2024. Towards practical metal–oxygen batteries: General discussion. Faraday Discussions. 248, 392–411."},"publication":"Faraday Discussions","scopus_import":"1","department":[{"_id":"StFr"}],"date_created":"2023-12-20T10:48:09Z","article_processing_charge":"No","year":"2024","intvolume":" 248","oa_version":"None","month":"01","publication_status":"published","article_type":"letter_note","author":[{"full_name":"Archer, Lynden A.","first_name":"Lynden A.","last_name":"Archer"},{"first_name":"Peter G.","full_name":"Bruce, Peter G.","last_name":"Bruce"},{"last_name":"Calvo","first_name":"Ernesto J.","full_name":"Calvo, Ernesto J."},{"full_name":"Dewar, Daniel","first_name":"Daniel","last_name":"Dewar"},{"full_name":"Ellison, James H. J.","first_name":"James H. J.","last_name":"Ellison"},{"last_name":"Freunberger","full_name":"Freunberger, Stefan Alexander","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"},{"full_name":"Gao, Xiangwen","first_name":"Xiangwen","last_name":"Gao"},{"full_name":"Hardwick, Laurence J.","first_name":"Laurence J.","last_name":"Hardwick"},{"first_name":"Gabriela","full_name":"Horwitz, Gabriela","last_name":"Horwitz"},{"first_name":"Jürgen","full_name":"Janek, Jürgen","last_name":"Janek"},{"last_name":"Johnson","first_name":"Lee R.","full_name":"Johnson, Lee R."},{"full_name":"Jordan, Jack W.","first_name":"Jack W.","last_name":"Jordan"},{"last_name":"Matsuda","first_name":"Shoichi","full_name":"Matsuda, Shoichi"},{"last_name":"Menkin","full_name":"Menkin, Svetlana","first_name":"Svetlana"},{"id":"d25d21ef-dc8d-11ea-abe3-ec4576307f48","full_name":"Mondal, Soumyadip","first_name":"Soumyadip","last_name":"Mondal"},{"full_name":"Qiu, Qianyuan","first_name":"Qianyuan","last_name":"Qiu"},{"last_name":"Samarakoon","first_name":"Thukshan","full_name":"Samarakoon, Thukshan"},{"last_name":"Temprano","full_name":"Temprano, Israel","first_name":"Israel"},{"last_name":"Uosaki","full_name":"Uosaki, Kohei","first_name":"Kohei"},{"last_name":"Vailaya","first_name":"Ganesh","full_name":"Vailaya, Ganesh"},{"first_name":"Eric D.","full_name":"Wachsman, Eric D.","last_name":"Wachsman"},{"last_name":"Wu","full_name":"Wu, Yiying","first_name":"Yiying"},{"first_name":"Shen","full_name":"Ye, Shen","last_name":"Ye"}],"doi":"10.1039/d3fd90062b","publisher":"Royal Society of Chemistry","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","status":"public","_id":"14701","page":"392-411","date_updated":"2025-09-04T11:34:30Z","pmid":1,"title":"Towards practical metal–oxygen batteries: General discussion","keyword":["Physical and Theoretical Chemistry"],"fulldoi":"https://doi.org/10.1039/d3fd90062b","isi":1,"language":[{"iso":"eng"}],"external_id":{"pmid":["38112202"],"isi":["001130090400001"]},"date_published":"2024-01-29T00:00:00Z","day":"29"},{"title":"Materials for stable metal–oxygen battery cathodes: general discussion","date_updated":"2025-09-04T11:35:09Z","page":"75-88","pmid":1,"type":"journal_article","status":"public","_id":"14702","doi":"10.1039/d3fd90059b","publisher":"Royal Society of Chemistry","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","day":"29","date_published":"2024-01-29T00:00:00Z","fulldoi":"https://doi.org/10.1039/d3fd90059b","isi":1,"language":[{"iso":"eng"}],"external_id":{"isi":["001130029600001"],"pmid":["38109098"]},"keyword":["Physical and Theoretical Chemistry"],"publication":"Faraday Discussions","department":[{"_id":"StFr"}],"scopus_import":"1","date_created":"2023-12-20T10:49:43Z","citation":{"chicago":"Attard, Gary A., Ernesto J. Calvo, Larry A. Curtiss, Daniel Dewar, James H. J. Ellison, Xiangwen Gao, Clare P. Grey, et al. “Materials for Stable Metal–Oxygen Battery Cathodes: General Discussion.” Faraday Discussions. Royal Society of Chemistry, 2024. https://doi.org/10.1039/d3fd90059b.","apa":"Attard, G. A., Calvo, E. J., Curtiss, L. A., Dewar, D., Ellison, J. H. J., Gao, X., … Ye, S. (2024). Materials for stable metal–oxygen battery cathodes: general discussion. Faraday Discussions. Royal Society of Chemistry. https://doi.org/10.1039/d3fd90059b","ieee":"G. A. Attard et al., “Materials for stable metal–oxygen battery cathodes: general discussion,” Faraday Discussions, vol. 248. Royal Society of Chemistry, pp. 75–88, 2024.","short":"G.A. Attard, E.J. Calvo, L.A. Curtiss, D. Dewar, J.H.J. Ellison, X. Gao, C.P. Grey, L.J. Hardwick, G. Horwitz, J. Janek, L.R. Johnson, J.W. Jordan, S. Matsuda, S. Mondal, A.R. Neale, N. Ortiz-Vitoriano, I. Temprano, G. Vailaya, E.D. Wachsman, H.-H. Wang, Y. Wu, S. Ye, Faraday Discussions 248 (2024) 75–88.","ama":"Attard GA, Calvo EJ, Curtiss LA, et al. Materials for stable metal–oxygen battery cathodes: general discussion. Faraday Discussions. 2024;248:75-88. doi:10.1039/d3fd90059b","mla":"Attard, Gary A., et al. “Materials for Stable Metal–Oxygen Battery Cathodes: General Discussion.” Faraday Discussions, vol. 248, Royal Society of Chemistry, 2024, pp. 75–88, doi:10.1039/d3fd90059b.","ista":"Attard GA, Calvo EJ, Curtiss LA, Dewar D, Ellison JHJ, Gao X, Grey CP, Hardwick LJ, Horwitz G, Janek J, Johnson LR, Jordan JW, Matsuda S, Mondal S, Neale AR, Ortiz-Vitoriano N, Temprano I, Vailaya G, Wachsman ED, Wang H-H, Wu Y, Ye S. 2024. Materials for stable metal–oxygen battery cathodes: general discussion. Faraday Discussions. 248, 75–88."},"quality_controlled":"1","volume":248,"publication_identifier":{"eissn":["1364-5498"],"issn":["1359-6640"]},"publication_status":"published","article_type":"letter_note","author":[{"last_name":"Attard","full_name":"Attard, Gary A.","first_name":"Gary A."},{"first_name":"Ernesto J.","full_name":"Calvo, Ernesto J.","last_name":"Calvo"},{"full_name":"Curtiss, Larry A.","first_name":"Larry A.","last_name":"Curtiss"},{"last_name":"Dewar","full_name":"Dewar, Daniel","first_name":"Daniel"},{"first_name":"James H. J.","full_name":"Ellison, James H. J.","last_name":"Ellison"},{"full_name":"Gao, Xiangwen","first_name":"Xiangwen","last_name":"Gao"},{"last_name":"Grey","first_name":"Clare P.","full_name":"Grey, Clare P."},{"first_name":"Laurence J.","full_name":"Hardwick, Laurence J.","last_name":"Hardwick"},{"first_name":"Gabriela","full_name":"Horwitz, Gabriela","last_name":"Horwitz"},{"last_name":"Janek","first_name":"Juergen","full_name":"Janek, Juergen"},{"full_name":"Johnson, Lee R.","first_name":"Lee R.","last_name":"Johnson"},{"last_name":"Jordan","full_name":"Jordan, Jack W.","first_name":"Jack W."},{"full_name":"Matsuda, Shoichi","first_name":"Shoichi","last_name":"Matsuda"},{"full_name":"Mondal, Soumyadip","first_name":"Soumyadip","id":"d25d21ef-dc8d-11ea-abe3-ec4576307f48","last_name":"Mondal"},{"first_name":"Alex R.","full_name":"Neale, Alex R.","last_name":"Neale"},{"full_name":"Ortiz-Vitoriano, Nagore","first_name":"Nagore","last_name":"Ortiz-Vitoriano"},{"first_name":"Israel","full_name":"Temprano, Israel","last_name":"Temprano"},{"last_name":"Vailaya","first_name":"Ganesh","full_name":"Vailaya, Ganesh"},{"first_name":"Eric D.","full_name":"Wachsman, Eric D.","last_name":"Wachsman"},{"first_name":"Hsien-Hau","full_name":"Wang, Hsien-Hau","last_name":"Wang"},{"last_name":"Wu","first_name":"Yiying","full_name":"Wu, Yiying"},{"first_name":"Shen","full_name":"Ye, Shen","last_name":"Ye"}],"oa_version":"None","intvolume":" 248","month":"01","article_processing_charge":"No","year":"2024"},{"status":"public","_id":"14711","project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program","call_identifier":"H2020","grant_number":"665385"},{"name":"Causes and consequences of population fragmentation","_id":"c08d3278-5a5b-11eb-8a69-fdb09b55f4b8","grant_number":"P32896"},{"name":"Polygenic Adaptation in a Metapopulation","_id":"34c872fe-11ca-11ed-8bc3-8534b82131e6","grant_number":"26380"}],"type":"dissertation","doi":"10.15479/at:ista:14711","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Institute of Science and Technology Austria","abstract":[{"lang":"eng","text":"In nature, different species find their niche in a range of environments, each with its unique characteristics. While some thrive in uniform (homogeneous) landscapes where environmental conditions stay relatively consistent across space, others traverse the complexities of spatially heterogeneous terrains. Comprehending how species are distributed and how they interact within these landscapes holds the key to gaining insights into their evolutionary dynamics while also informing conservation and management strategies.\r\n\r\nFor species inhabiting heterogeneous landscapes, when the rate of dispersal is low compared to spatial fluctuations in selection pressure, localized adaptations may emerge. Such adaptation in response to varying selection strengths plays an important role in the persistence of populations in our rapidly changing world. Hence, species in nature are continuously in a struggle to adapt to local environmental conditions, to ensure their continued survival. Natural populations can often adapt in time scales short enough for evolutionary changes to influence ecological dynamics and vice versa, thereby creating a feedback between evolution and demography. The analysis of this feedback and the relative contributions of gene flow, demography, drift, and natural selection to genetic variation and differentiation has remained a recurring theme in evolutionary biology. Nevertheless, the effective role of these forces in maintaining variation and shaping patterns of diversity is not fully understood. Even in homogeneous environments devoid of local adaptations, such understanding remains elusive. Understanding this feedback is crucial, for example in determining the conditions under which extinction risk can be mitigated in peripheral populations subject to deleterious mutation accumulation at the edges of species’ ranges\r\nas well as in highly fragmented populations.\r\n\r\nIn this thesis we explore both uniform and spatially heterogeneous metapopulations, investigating and providing theoretical insights into the dynamics of local adaptation in the latter and examining the dynamics of load and extinction as well as the impact of joint ecological and evolutionary (eco-evolutionary) dynamics in the former. The thesis is divided into 5 chapters.\r\n\r\nChapter 1 provides a general introduction into the subject matter, clarifying concepts and ideas used throughout the thesis. In chapter 2, we explore how fast a species distributed across a heterogeneous landscape adapts to changing conditions marked by alterations in carrying capacity, selection pressure, and migration rate.\r\n\r\nIn chapter 3, we investigate how migration selection and drift influences adaptation and the maintenance of variation in a metapopulation with three habitats, an extension of previous models of adaptation in two habitats. We further develop analytical approximations for the critical threshold required for polymorphism to persist.\r\n\r\nThe focus of chapter 4 of the thesis is on understanding the interplay between ecology and evolution as coupled processes. We investigate how eco-evolutionary feedback between migration, selection, drift, and demography influences eco-evolutionary outcomes in marginal populations subject to deleterious mutation accumulation. Using simulations as well as theoretical approximations of the coupled dynamics of population size and allele frequency, we analyze how gene flow from a large mainland source influences genetic load and population size on an island (i.e., in a marginal population) under genetically realistic assumptions. Analyses of this sort are important because small isolated populations, are repeatedly affected by complex interactions between ecological and evolutionary processes, which can lead to their death. Understanding these interactions can therefore provide an insight into the conditions under which extinction risk can be mitigated in peripheral populations thus, contributing to conservation and restoration efforts.\r\n\r\nChapter 5 extends the analysis in chapter 4 to consider the dynamics of load (due to deleterious mutation accumulation) and extinction risk in a metapopulation. We explore the role of gene flow, selection, and dominance on load and extinction risk and further pinpoint critical thresholds required for metapopulation persistence.\r\n\r\nOverall this research contributes to our understanding of ecological and evolutionary mechanisms that shape species’ persistence in fragmented landscapes, a crucial foundation for successful conservation efforts and biodiversity management."}],"file_date_updated":"2024-01-03T18:31:34Z","title":"Local adaptation, genetic load and extinction in metapopulations","license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","page":"183","date_updated":"2026-04-07T12:54:29Z","tmp":{"image":"/images/cc_by_nc_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"day":"19","date_published":"2024-01-19T00:00:00Z","language":[{"iso":"eng"}],"file":[{"access_level":"closed","file_id":"14730","content_type":"application/zip","file_name":"FinalSubmission_Thesis_OLUSANYA.zip","file_size":16986244,"checksum":"de179b1c6758f182ff0c70d8b38c1501","date_updated":"2024-01-03T18:30:13Z","date_created":"2024-01-03T18:30:13Z","relation":"source_file","creator":"oolusany"},{"file_size":6460403,"checksum":"0e331585e3cd4823320aab4e69e64ccf","date_updated":"2024-01-03T18:31:34Z","date_created":"2024-01-03T18:31:34Z","relation":"main_file","success":1,"creator":"oolusany","access_level":"open_access","file_id":"14731","file_name":"FinalSubmission2_Thesis_OLUSANYA.pdf","content_type":"application/pdf"}],"fulldoi":"https://doi.org/10.15479/at:ista:14711","OA_place":"publisher","publication_identifier":{"issn":["2663-337X"]},"ec_funded":1,"supervisor":[{"last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","first_name":"Nicholas H"},{"last_name":"Polechova","first_name":"Jitka","full_name":"Polechova, Jitka"},{"first_name":"Himani","full_name":"Sachdeva, Himani","last_name":"Sachdeva"}],"date_created":"2023-12-26T22:49:53Z","department":[{"_id":"NiBa"},{"_id":"GradSch"}],"acknowledged_ssus":[{"_id":"SSU"}],"has_accepted_license":"1","alternative_title":["ISTA Thesis"],"related_material":{"record":[{"id":"10787","relation":"part_of_dissertation","status":"public"},{"id":"10658","status":"public","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"14732"}]},"citation":{"ista":"Olusanya OO. 2024. Local adaptation, genetic load and extinction in metapopulations. Institute of Science and Technology Austria.","ama":"Olusanya OO. Local adaptation, genetic load and extinction in metapopulations. 2024. doi:10.15479/at:ista:14711","mla":"Olusanya, Oluwafunmilola O. Local Adaptation, Genetic Load and Extinction in Metapopulations. Institute of Science and Technology Austria, 2024, doi:10.15479/at:ista:14711.","short":"O.O. Olusanya, Local Adaptation, Genetic Load and Extinction in Metapopulations, Institute of Science and Technology Austria, 2024.","apa":"Olusanya, O. O. (2024). Local adaptation, genetic load and extinction in metapopulations. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:14711","ieee":"O. O. Olusanya, “Local adaptation, genetic load and extinction in metapopulations,” Institute of Science and Technology Austria, 2024.","chicago":"Olusanya, Oluwafunmilola O. “Local Adaptation, Genetic Load and Extinction in Metapopulations.” Institute of Science and Technology Austria, 2024. https://doi.org/10.15479/at:ista:14711."},"corr_author":"1","oa_version":"Published Version","month":"01","oa":1,"year":"2024","degree_awarded":"PhD","article_processing_charge":"No","ddc":["576"],"author":[{"last_name":"Olusanya","first_name":"Oluwafunmilola O","full_name":"Olusanya, Oluwafunmilola O","orcid":"0000-0003-1971-8314","id":"41AD96DC-F248-11E8-B48F-1D18A9856A87"}],"publication_status":"published"},{"doi":"10.1093/plcell/koad324","publisher":"Oxford University Press","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","status":"public","_id":"14726","date_updated":"2024-07-16T11:18:46Z","pmid":1,"abstract":[{"text":"Autocrine signaling pathways regulated by RAPID ALKALINIZATION FACTORs (RALFs) control cell wall integrity during pollen tube germination and growth in Arabidopsis (Arabidopsis thaliana). To investigate the role of pollen-specific RALFs in another plant species, we combined gene expression data with phylogenetic and biochemical studies to identify candidate orthologs in maize (Zea mays). We show that Clade IB ZmRALF2/3 mutations, but not Clade III ZmRALF1/5 mutations, cause cell wall instability in the sub-apical region of the growing pollen tube. ZmRALF2/3 are mainly located in the cell wall and are partially able to complement the pollen germination defect of their Arabidopsis orthologs AtRALF4/19. Mutations in ZmRALF2/3 compromise pectin distribution patterns leading to altered cell wall organization and thickness culminating in pollen tube burst. Clade IB, but not Clade III ZmRALFs, strongly interact as ligands with the pollen-specific Catharanthus roseus RLK1-like (CrRLK1L) receptor kinases Zea mays FERONIA-like (ZmFERL) 4/7/9, LORELEI-like glycosylphosphatidylinositol-anchor (LLG) proteins Zea mays LLG 1 and 2 (ZmLLG1/2) and Zea mays pollen extension-like (PEX) cell wall proteins ZmPEX2/4. Notably, ZmFERL4 outcompetes ZmLLG2 and ZmPEX2 outcompetes ZmFERL4 for ZmRALF2 binding. Based on these data, we suggest that Clade IB RALFs act in a dual role as cell wall components and extracellular sensors to regulate cell wall integrity and thickness during pollen tube growth in maize and probably other plants.","lang":"eng"}],"title":"The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"keyword":["Cell Biology","Plant Science"],"fulldoi":"https://doi.org/10.1093/plcell/koad324","language":[{"iso":"eng"}],"external_id":{"pmid":["38142229"]},"date_published":"2024-05-01T00:00:00Z","day":"01","article_number":"koad324","quality_controlled":"1","publication_identifier":{"eissn":["1532-298X"],"issn":["1040-4651"]},"volume":36,"extern":"1","has_accepted_license":"1","citation":{"apa":"Zhou, L.-Z., Wang, L., Chen, X., Ge, Z., Mergner, J., Li, X., … Dresselhaus, T. (2024). The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize. The Plant Cell. Oxford University Press. https://doi.org/10.1093/plcell/koad324","ieee":"L.-Z. Zhou et al., “The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize,” The Plant Cell, vol. 36, no. 5. Oxford University Press, 2024.","short":"L.-Z. Zhou, L. Wang, X. Chen, Z. Ge, J. Mergner, X. Li, B. Küster, G. Längst, L.-J. Qu, T. Dresselhaus, The Plant Cell 36 (2024).","chicago":"Zhou, Liang-Zi, Lele Wang, Xia Chen, Zengxiang Ge, Julia Mergner, Xingli Li, Bernhard Küster, Gernot Längst, Li-Jia Qu, and Thomas Dresselhaus. “The RALF Signaling Pathway Regulates Cell Wall Integrity during Pollen Tube Growth in Maize.” The Plant Cell. Oxford University Press, 2024. https://doi.org/10.1093/plcell/koad324.","ista":"Zhou L-Z, Wang L, Chen X, Ge Z, Mergner J, Li X, Küster B, Längst G, Qu L-J, Dresselhaus T. 2024. The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize. The Plant Cell. 36(5), koad324.","ama":"Zhou L-Z, Wang L, Chen X, et al. The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize. The Plant Cell. 2024;36(5). doi:10.1093/plcell/koad324","mla":"Zhou, Liang-Zi, et al. “The RALF Signaling Pathway Regulates Cell Wall Integrity during Pollen Tube Growth in Maize.” The Plant Cell, vol. 36, no. 5, koad324, Oxford University Press, 2024, doi:10.1093/plcell/koad324."},"publication":"The Plant Cell","scopus_import":"1","date_created":"2024-01-02T11:19:37Z","article_processing_charge":"No","oa":1,"year":"2024","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/plcell/koad324"}],"issue":"5","intvolume":" 36","oa_version":"Published Version","month":"05","article_type":"original","publication_status":"published","author":[{"first_name":"Liang-Zi","full_name":"Zhou, Liang-Zi","last_name":"Zhou"},{"last_name":"Wang","full_name":"Wang, Lele","first_name":"Lele"},{"last_name":"Chen","full_name":"Chen, Xia","first_name":"Xia"},{"last_name":"Ge","id":"f43371a3-09ff-11eb-8013-bd0c6a2f6de8","full_name":"Ge, Zengxiang","orcid":"0000-0001-9381-3577","first_name":"Zengxiang"},{"last_name":"Mergner","first_name":"Julia","full_name":"Mergner, Julia"},{"full_name":"Li, Xingli","first_name":"Xingli","last_name":"Li"},{"last_name":"Küster","full_name":"Küster, Bernhard","first_name":"Bernhard"},{"last_name":"Längst","first_name":"Gernot","full_name":"Längst, Gernot"},{"last_name":"Qu","first_name":"Li-Jia","full_name":"Qu, Li-Jia"},{"last_name":"Dresselhaus","first_name":"Thomas","full_name":"Dresselhaus, Thomas"}],"ddc":["580"]},{"has_accepted_license":"1","citation":{"chicago":"Jethwa, Rajesh B, Dominic Hey, Rachel N. Kerber, Andrew D. Bond, Dominic S. Wright, and Clare P. Grey. “Exploring the Landscape of Heterocyclic Quinones for Redox Flow Batteries.” ACS Applied Energy Materials. American Chemical Society, 2024. https://doi.org/10.1021/acsaem.3c02223.","apa":"Jethwa, R. B., Hey, D., Kerber, R. N., Bond, A. D., Wright, D. S., & Grey, C. P. (2024). Exploring the landscape of heterocyclic quinones for redox flow batteries. ACS Applied Energy Materials. American Chemical Society. https://doi.org/10.1021/acsaem.3c02223","ieee":"R. B. Jethwa, D. Hey, R. N. Kerber, A. D. Bond, D. S. Wright, and C. P. Grey, “Exploring the landscape of heterocyclic quinones for redox flow batteries,” ACS Applied Energy Materials, vol. 7, no. 2. American Chemical Society, pp. 414–426, 2024.","short":"R.B. Jethwa, D. Hey, R.N. Kerber, A.D. Bond, D.S. Wright, C.P. Grey, ACS Applied Energy Materials 7 (2024) 414–426.","ama":"Jethwa RB, Hey D, Kerber RN, Bond AD, Wright DS, Grey CP. Exploring the landscape of heterocyclic quinones for redox flow batteries. ACS Applied Energy Materials. 2024;7(2):414-426. doi:10.1021/acsaem.3c02223","mla":"Jethwa, Rajesh B., et al. “Exploring the Landscape of Heterocyclic Quinones for Redox Flow Batteries.” ACS Applied Energy Materials, vol. 7, no. 2, American Chemical Society, 2024, pp. 414–26, doi:10.1021/acsaem.3c02223.","ista":"Jethwa RB, Hey D, Kerber RN, Bond AD, Wright DS, Grey CP. 2024. Exploring the landscape of heterocyclic quinones for redox flow batteries. ACS Applied Energy Materials. 7(2), 414–426."},"publication":"ACS Applied Energy Materials","scopus_import":"1","department":[{"_id":"StFr"}],"date_created":"2024-01-05T09:20:48Z","quality_controlled":"1","publication_identifier":{"eissn":["2574-0962"]},"volume":7,"ec_funded":1,"article_type":"original","publication_status":"published","author":[{"id":"4cc538d5-803f-11ed-ab7e-8139573aad8f","full_name":"Jethwa, Rajesh B","orcid":"0000-0002-0404-4356","first_name":"Rajesh B","last_name":"Jethwa"},{"full_name":"Hey, Dominic","first_name":"Dominic","last_name":"Hey"},{"full_name":"Kerber, Rachel N.","first_name":"Rachel N.","last_name":"Kerber"},{"first_name":"Andrew D.","full_name":"Bond, Andrew D.","last_name":"Bond"},{"first_name":"Dominic S.","full_name":"Wright, Dominic S.","last_name":"Wright"},{"last_name":"Grey","full_name":"Grey, Clare P.","first_name":"Clare P."}],"ddc":["540"],"article_processing_charge":"Yes (in subscription journal)","year":"2024","oa":1,"issue":"2","main_file_link":[{"url":"https://doi.org/10.1021/acsaem.3c02223","open_access":"1"}],"intvolume":" 7","oa_version":"Published Version","month":"01","date_updated":"2025-09-04T11:36:32Z","page":"414-426","pmid":1,"file_date_updated":"2024-07-16T11:59:24Z","abstract":[{"text":"Redox flow batteries (RFBs) rely on the development of cheap, highly soluble, and high-energy-density electrolytes. Several candidate quinones have already been investigated in the literature as two-electron anolytes or catholytes, benefiting from fast kinetics, high tunability, and low cost. Here, an investigation of nitrogen-rich fused heteroaromatic quinones was carried out to explore avenues for electrolyte development. These quinones were synthesized and screened by using electrochemical techniques. The most promising candidate, 4,8-dioxo-4,8-dihydrobenzo[1,2-d:4,5-d′]bis([1,2,3]triazole)-1,5-diide (−0.68 V(SHE)), was tested in both an asymmetric and symmetric full-cell setup resulting in capacity fade rates of 0.35% per cycle and 0.0124% per cycle, respectively. In situ ultraviolet-visible spectroscopy (UV–Vis), nuclear magnetic resonance (NMR), and electron paramagnetic resonance (EPR) spectroscopies were used to investigate the electrochemical stability of the charged species during operation. UV–Vis spectroscopy, supported by density functional theory (DFT) modeling, reaffirmed that the two-step charging mechanism observed during battery operation consisted of two, single-electron transfers. The radical concentration during battery operation and the degree of delocalization of the unpaired electron were quantified with NMR and EPR spectroscopy.","lang":"eng"}],"title":"Exploring the landscape of heterocyclic quinones for redox flow batteries","doi":"10.1021/acsaem.3c02223","publisher":"American Chemical Society","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413"}],"_id":"14733","status":"public","isi":1,"fulldoi":"https://doi.org/10.1021/acsaem.3c02223","file":[{"content_type":"application/pdf","file_name":"2024_ACSAppElecMaterials_Jethwa.pdf","access_level":"open_access","file_id":"17262","relation":"main_file","date_created":"2024-07-16T11:59:24Z","success":1,"creator":"dernst","file_size":5607177,"checksum":"2841e86a041d249ac0df2531b7f9aec1","date_updated":"2024-07-16T11:59:24Z"}],"language":[{"iso":"eng"}],"external_id":{"pmid":["38273966"],"isi":["001146733200001"]},"day":"22","date_published":"2024-01-22T00:00:00Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"keyword":["Electrical and Electronic Engineering","Materials Chemistry","Electrochemistry","Energy Engineering and Power Technology","Chemical Engineering (miscellaneous)"]},{"citation":{"ieee":"S. Wan et al., “Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric performance in Cu3SbSe4,” Small Methods, vol. 8, no. 8. Wiley, 2024.","apa":"Wan, S., Xiao, S., Li, M., Wang, X., Lim, K. H., Hong, M., … Liu, Y. (2024). Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric performance in Cu3SbSe4. Small Methods. Wiley. https://doi.org/10.1002/smtd.202301377","short":"S. Wan, S. Xiao, M. Li, X. Wang, K.H. Lim, M. Hong, M. Ibáñez, A. Cabot, Y. Liu, Small Methods 8 (2024).","chicago":"Wan, Shanhong, Shanshan Xiao, Mingquan Li, Xin Wang, Khak Ho Lim, Min Hong, Maria Ibáñez, Andreu Cabot, and Yu Liu. “Band Engineering through Pb-Doping of Nanocrystal Building Blocks to Enhance Thermoelectric Performance in Cu3SbSe4.” Small Methods. Wiley, 2024. https://doi.org/10.1002/smtd.202301377.","ista":"Wan S, Xiao S, Li M, Wang X, Lim KH, Hong M, Ibáñez M, Cabot A, Liu Y. 2024. Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric performance in Cu3SbSe4. Small Methods. 8(8), 2301377.","ama":"Wan S, Xiao S, Li M, et al. Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric performance in Cu3SbSe4. Small Methods. 2024;8(8). doi:10.1002/smtd.202301377","mla":"Wan, Shanhong, et al. “Band Engineering through Pb-Doping of Nanocrystal Building Blocks to Enhance Thermoelectric Performance in Cu3SbSe4.” Small Methods, vol. 8, no. 8, 2301377, Wiley, 2024, doi:10.1002/smtd.202301377."},"publication":"Small Methods","scopus_import":"1","department":[{"_id":"MaIb"}],"date_created":"2024-01-07T23:00:51Z","acknowledgement":"Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (Grants No. 22209034), the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province (Grant No. 2022LCX002). K.H.L. acknowledges financial support from the National Natural Science Foundation of China (NSFC) (Grant No. 22208293). M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation.","article_number":"2301377","OA_type":"closed access","quality_controlled":"1","volume":8,"publication_identifier":{"eissn":["2366-9608"]},"publication_status":"published","article_type":"original","author":[{"last_name":"Wan","full_name":"Wan, Shanhong","first_name":"Shanhong"},{"first_name":"Shanshan","full_name":"Xiao, Shanshan","last_name":"Xiao"},{"last_name":"Li","first_name":"Mingquan","full_name":"Li, Mingquan"},{"full_name":"Wang, Xin","first_name":"Xin","last_name":"Wang"},{"first_name":"Khak Ho","full_name":"Lim, Khak Ho","last_name":"Lim"},{"last_name":"Hong","first_name":"Min","full_name":"Hong, Min"},{"last_name":"Ibáñez","first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"},{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","first_name":"Yu","last_name":"Liu"}],"article_processing_charge":"No","year":"2024","intvolume":" 8","oa_version":"None","issue":"8","month":"08","date_updated":"2025-09-04T11:37:19Z","pmid":1,"abstract":[{"text":"Developing cost-effective and high-performance thermoelectric (TE) materials to assemble efficient TE devices presents a multitude of challenges and opportunities. Cu3SbSe4 is a promising p-type TE material based on relatively earth abundant elements. However, the challenge lies in its poor electrical conductivity. Herein, an efficient and scalable solution-based approach is developed to synthesize high-quality Cu3SbSe4 nanocrystals doped with Pb at the Sb site. After ligand displacement and annealing treatments, the dried powders are consolidated into dense pellets, and their TE properties are investigated. Pb doping effectively increases the charge carrier concentration, resulting in a significant increase in electrical conductivity, while the Seebeck coefficients remain consistently high. The calculated band structure shows that Pb doping induces band convergence, thereby increasing the effective mass. Furthermore, the large ionic radius of Pb2+ results in the generation of additional point and plane defects and interphases, dramatically enhancing phonon scattering, which significantly decreases the lattice thermal conductivity at high temperatures. Overall, a maximum figure of merit (zTmax) ≈ 0.85 at 653 K is obtained in Cu3Sb0.97Pb0.03Se4. This represents a 1.6-fold increase compared to the undoped sample and exceeds most doped Cu3SbSe4-based materials produced by solid-state, demonstrating advantages of versatility and cost-effectiveness using a solution-based technology.","lang":"eng"}],"title":"Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric performance in Cu3SbSe4","doi":"10.1002/smtd.202301377","publisher":"Wiley","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"type":"journal_article","_id":"14734","status":"public","fulldoi":"https://doi.org/10.1002/smtd.202301377","isi":1,"language":[{"iso":"eng"}],"external_id":{"isi":["001133369800001"],"pmid":["38152986"]},"day":"01","date_published":"2024-08-01T00:00:00Z"},{"publication":"2024 Proceedings of the Symposium on Algorithm Engineering and Experiments","date_created":"2024-01-09T16:22:47Z","scopus_import":"1","department":[{"_id":"MoHe"}],"citation":{"ama":"Henzinger M, Saulpic D, Sidl L. Experimental evaluation of fully dynamic k-means via coresets. In: 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments. Society for Industrial and Applied Mathematics; 2024:220-233. doi:10.1137/1.9781611977929.17","mla":"Henzinger, Monika, et al. “Experimental Evaluation of Fully Dynamic K-Means via Coresets.” 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments, Society for Industrial and Applied Mathematics, 2024, pp. 220–33, doi:10.1137/1.9781611977929.17.","ista":"Henzinger M, Saulpic D, Sidl L. 2024. Experimental evaluation of fully dynamic k-means via coresets. 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments. ALENEX: Workshop on Algorithm Engineering and Experiments, 220–233.","chicago":"Henzinger, Monika, David Saulpic, and Leonhard Sidl. “Experimental Evaluation of Fully Dynamic K-Means via Coresets.” In 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments, 220–33. Society for Industrial and Applied Mathematics, 2024. https://doi.org/10.1137/1.9781611977929.17.","apa":"Henzinger, M., Saulpic, D., & Sidl, L. (2024). Experimental evaluation of fully dynamic k-means via coresets. In 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments (pp. 220–233). Alexandria, VA, United States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611977929.17","ieee":"M. Henzinger, D. Saulpic, and L. Sidl, “Experimental evaluation of fully dynamic k-means via coresets,” in 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments, Alexandria, VA, United States, 2024, pp. 220–233.","short":"M. Henzinger, D. Saulpic, L. Sidl, in:, 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments, Society for Industrial and Applied Mathematics, 2024, pp. 220–233."},"corr_author":"1","quality_controlled":"1","arxiv":1,"publication_identifier":{"eisbn":["9781611977929"]},"ec_funded":1,"acknowledgement":"This project has received funding from the Euro-pean Research Council (ERC) under the EuropeanUnion’s Horizon 2020 research and innovation programme (Grant agreement No. 101019564 “The De-sign of Modern Fully Dynamic Data Structures (Mo-DynStruct)” and the Austrian Science Fund (FWF)project Z 422-N, project “Static and Dynamic Hierar-chical Graph Decompositions”, I 5982-N, and project“Fast Algorithms for a Reactive Network Layer (Re-actNet)”, P 33775-N, with additional funding from thenetidee SCIENCE Stiftung, 2020–2024.D. Sauplic has received funding from the Euro-pean Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreementNo 101034413.","author":[{"last_name":"Henzinger","orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H","first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630"},{"last_name":"Saulpic","id":"f8e48cf0-b0ff-11ed-b0e9-b4c35598f964","first_name":"David","full_name":"Saulpic, David"},{"last_name":"Sidl","id":"8b563fd0-b441-11ee-9101-a3891c61efa6","first_name":"Leonhard","full_name":"Sidl, Leonhard"}],"publication_status":"published","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2310.18034"}],"oa_version":"Preprint","month":"01","year":"2024","oa":1,"article_processing_charge":"No","abstract":[{"text":"For a set of points in Rd, the Euclidean k-means problems consists of finding k centers such that the sum of distances squared from each data point to its closest center is minimized. Coresets are one the main tools developed recently to solve this problem in a big data context. They allow to compress the initial dataset while preserving its structure: running any algorithm on the coreset provides a guarantee almost equivalent to running it on the full data. In this work, we study coresets in a fully-dynamic setting: points are added and deleted with the goal to efficiently maintain a coreset with which a k-means solution can be computed. Based on an algorithm from Henzinger and Kale [ESA'20], we present an efficient and practical implementation of a fully dynamic coreset algorithm, that improves the running time by up to a factor of 20 compared to our non-optimized implementation of the algorithm by Henzinger and Kale, without sacrificing more than 7% on the quality of the k-means solution.","lang":"eng"}],"conference":{"name":"ALENEX: Workshop on Algorithm Engineering and Experiments","start_date":"2024-01-07","location":"Alexandria, VA, United States","end_date":"2024-01-08"},"title":"Experimental evaluation of fully dynamic k-means via coresets","page":"220-233","date_updated":"2025-04-14T13:50:50Z","_id":"14769","status":"public","type":"conference","project":[{"grant_number":"101019564","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62","name":"The design and evaluation of modern fully dynamic data structures","call_identifier":"H2020"},{"grant_number":"Z00422","name":"Efficient algorithms","_id":"34def286-11ca-11ed-8bc3-da5948e1613c"},{"_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","name":"Static and Dynamic Hierarchical Graph Decompositions","grant_number":"I05982"},{"_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","name":"Fast Algorithms for a Reactive Network Layer","grant_number":"P33775"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"}],"doi":"10.1137/1.9781611977929.17","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Society for Industrial and Applied Mathematics","day":"04","date_published":"2024-01-04T00:00:00Z","language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1137/1.9781611977929.17","external_id":{"arxiv":["2310.18034"]}}]