[{"author":[{"full_name":"Giubertoni, Giulia","last_name":"Giubertoni","first_name":"Giulia"},{"first_name":"Liru","last_name":"Feng","full_name":"Feng, Liru"},{"full_name":"Klein, Kevin","first_name":"Kevin","last_name":"Klein"},{"full_name":"Giannetti, Guido","first_name":"Guido","last_name":"Giannetti"},{"full_name":"Rutten, Luco","first_name":"Luco","last_name":"Rutten"},{"full_name":"Choi, Yeji","first_name":"Yeji","last_name":"Choi"},{"first_name":"Anouk","last_name":"Van Der Net","full_name":"Van Der Net, Anouk"},{"full_name":"Castro-Linares, Gerard","first_name":"Gerard","last_name":"Castro-Linares"},{"first_name":"Federico","last_name":"Caporaletti","full_name":"Caporaletti, Federico"},{"first_name":"Dimitra","last_name":"Micha","full_name":"Micha, Dimitra"},{"full_name":"Hunger, Johannes","last_name":"Hunger","first_name":"Johannes"},{"first_name":"Antoine","last_name":"Deblais","full_name":"Deblais, Antoine"},{"full_name":"Bonn, Daniel","first_name":"Daniel","last_name":"Bonn"},{"last_name":"Sommerdijk","first_name":"Nico","full_name":"Sommerdijk, Nico"},{"last_name":"Šarić","first_name":"Anđela","full_name":"Šarić, Anđela","orcid":"0000-0002-7854-2139","id":"bf63d406-f056-11eb-b41d-f263a6566d8b"},{"full_name":"Ilie, Ioana M.","last_name":"Ilie","first_name":"Ioana M."},{"full_name":"Koenderink, Gijsje H.","last_name":"Koenderink","first_name":"Gijsje H."},{"last_name":"Woutersen","first_name":"Sander","full_name":"Woutersen, Sander"}],"day":"12","related_material":{"record":[{"id":"15126","status":"public","relation":"research_data"}]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","external_id":{"pmid":["38451946"],"isi":["001206387400001"]},"article_type":"original","file":[{"file_size":12952586,"date_updated":"2024-03-19T10:22:42Z","file_name":"2024_PNAS_Giubertoni.pdf","relation":"main_file","access_level":"open_access","creator":"dernst","success":1,"file_id":"15125","content_type":"application/pdf","checksum":"a3f7fdc29dd9f0a38952ab4e322b3a05","date_created":"2024-03-19T10:22:42Z"}],"has_accepted_license":"1","title":"Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration","date_created":"2024-03-17T23:00:57Z","publication":"Proceedings of the National Academy of Sciences of the United States of America","file_date_updated":"2024-03-19T10:22:42Z","date_updated":"2025-09-04T13:03:56Z","fulldoi":"https://doi.org/10.1073/pnas.2313162121","issue":"11","month":"03","ddc":["550"],"isi":1,"department":[{"_id":"AnSa"}],"scopus_import":"1","article_number":"e2313162121","oa":1,"article_processing_charge":"Yes (in subscription journal)","pmid":1,"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Water is known to play an important role in collagen self-assembly, but it is still largely unclear how water–collagen interactions influence the assembly process and determine the fibril network properties. Here, we use the H2O/D2O isotope effect on the hydrogen-bond strength in water to investigate the role of hydration in collagen self-assembly. We dissolve collagen in H2O and D2O and compare the growth kinetics and the structure of the collagen assemblies formed in these water isotopomers. Surprisingly, collagen assembly occurs ten times faster in D2O than in H2O, and collagen in D2O self-assembles into much thinner fibrils, that form a more inhomogeneous and softer network, with a fourfold reduction in elastic modulus when compared to H2O. Combining spectroscopic measurements with atomistic simulations, we show that collagen in D2O is less hydrated than in H2O. This partial dehydration lowers the enthalpic penalty for water removal and reorganization at the collagen–water interface, increasing the self-assembly rate and the number of nucleation centers, leading to thinner fibrils and a softer network. Coarse-grained simulations show that the acceleration in the initial nucleation rate can be reproduced by the enhancement of electrostatic interactions. These results show that water acts as a mediator between collagen monomers, by modulating their interactions so as to optimize the assembly process and, thus, the final network properties. We believe that isotopically modulating the hydration of proteins can be a valuable method to investigate the role of water in protein structural dynamics and protein self-assembly."}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"intvolume":"       121","citation":{"short":"G. Giubertoni, L. Feng, K. Klein, G. Giannetti, L. Rutten, Y. Choi, A. Van Der Net, G. Castro-Linares, F. Caporaletti, D. Micha, J. Hunger, A. Deblais, D. Bonn, N. Sommerdijk, A. Šarić, I.M. Ilie, G.H. Koenderink, S. Woutersen, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","ista":"Giubertoni G, Feng L, Klein K, Giannetti G, Rutten L, Choi Y, Van Der Net A, Castro-Linares G, Caporaletti F, Micha D, Hunger J, Deblais A, Bonn D, Sommerdijk N, Šarić A, Ilie IM, Koenderink GH, Woutersen S. 2024. Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration. Proceedings of the National Academy of Sciences of the United States of America. 121(11), e2313162121.","ieee":"G. Giubertoni <i>et al.</i>, “Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 11. National Academy of Sciences, 2024.","chicago":"Giubertoni, Giulia, Liru Feng, Kevin Klein, Guido Giannetti, Luco Rutten, Yeji Choi, Anouk Van Der Net, et al. “Elucidating the Role of Water in Collagen Self-Assembly by Isotopically Modulating Collagen Hydration.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2313162121\">https://doi.org/10.1073/pnas.2313162121</a>.","mla":"Giubertoni, Giulia, et al. “Elucidating the Role of Water in Collagen Self-Assembly by Isotopically Modulating Collagen Hydration.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 11, e2313162121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2313162121\">10.1073/pnas.2313162121</a>.","ama":"Giubertoni G, Feng L, Klein K, et al. Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(11). doi:<a href=\"https://doi.org/10.1073/pnas.2313162121\">10.1073/pnas.2313162121</a>","apa":"Giubertoni, G., Feng, L., Klein, K., Giannetti, G., Rutten, L., Choi, Y., … Woutersen, S. (2024). Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2313162121\">https://doi.org/10.1073/pnas.2313162121</a>"},"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"publication_status":"published","publisher":"National Academy of Sciences","year":"2024","status":"public","date_published":"2024-03-12T00:00:00Z","_id":"15116","acknowledgement":"We thank Dr. Steven Roeters (Aarhus University), Dr. Federica Burla, and Prof. Dr. Mischa Bonn (Institute for Polymer Research, Mainz, Germany) for the useful discussions. We thank Dr. Wim Roeterdink and Michiel Hilberts for technical support. G.H.K. acknowledges financial support by the “BaSyC Building a Synthetic Cell” Gravitation grant (024.003.019) of The Netherlands Ministry of Education, Culture and Science (OCW) and The Netherlands Organization for Scientific Research and from NWO grant OCENW.GROOT.2019.022. This work has received support from the National Research Foundation of Korea (NRF), funded by the Ministry of Science and ICT, under Grant No. 2022K1A3A1A04062969. This publication is part of the project (with Project Number VI.Veni.212.240) of the research programme NWO Talent Programme Veni 2021, which is financed by the Dutch Research Council (NWO). I.M.I. acknowledges support from the Sectorplan Bèta & Techniek of the Dutch Government and the Dementia Research - Synapsis Foundation Switzerland. A.Š. and K.K. acknowledge support from Royal Society and European Research Council Starting Grant. G. Giubertoni kindly thanks to the Care4Bones community and the Collagen Café community for reminding that we do not own the knowledge we create, but it is, rather, a collective resource intended for the advancement of human progress.","doi":"10.1073/pnas.2313162121","volume":121,"quality_controlled":"1"},{"publication":"Nature Microbiology","date_created":"2024-03-17T23:00:58Z","title":"Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division","issue":"3","month":"03","date_updated":"2026-04-07T12:27:57Z","fulldoi":"https://doi.org/10.1038/s41564-024-01600-5","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","related_material":{"record":[{"id":"20741","status":"public","relation":"dissertation_contains"}]},"type":"journal_article","day":"04","author":[{"full_name":"Nußbaum, Phillip","last_name":"Nußbaum","first_name":"Phillip"},{"last_name":"Kureisaite-Ciziene","first_name":"Danguole","full_name":"Kureisaite-Ciziene, Danguole"},{"first_name":"Dom","last_name":"Bellini","full_name":"Bellini, Dom"},{"last_name":"Van Der Does","first_name":"Chris","full_name":"Van Der Does, Chris"},{"full_name":"Kojic, Marko","orcid":"0000-0001-7244-8128","id":"73e7ecd4-dc85-11ea-9058-88a16394b160","first_name":"Marko","last_name":"Kojic"},{"last_name":"Taib","first_name":"Najwa","full_name":"Taib, Najwa"},{"first_name":"Anna","last_name":"Yeates","full_name":"Yeates, Anna"},{"last_name":"Tourte","first_name":"Maxime","full_name":"Tourte, Maxime"},{"last_name":"Gribaldo","first_name":"Simonetta","full_name":"Gribaldo, Simonetta"},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin","orcid":"0000-0001-7309-9724","last_name":"Loose","first_name":"Martin"},{"first_name":"Jan","last_name":"Löwe","full_name":"Löwe, Jan"},{"full_name":"Albers, Sonja Verena","last_name":"Albers","first_name":"Sonja Verena"}],"page":"698-711","article_type":"original","external_id":{"isi":["001183270800021"],"pmid":["38443575"]},"intvolume":"         9","citation":{"ista":"Nußbaum P, Kureisaite-Ciziene D, Bellini D, Van Der Does C, Kojic M, Taib N, Yeates A, Tourte M, Gribaldo S, Loose M, Löwe J, Albers SV. 2024. Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division. Nature Microbiology. 9(3), 698–711.","short":"P. Nußbaum, D. Kureisaite-Ciziene, D. Bellini, C. Van Der Does, M. Kojic, N. Taib, A. Yeates, M. Tourte, S. Gribaldo, M. Loose, J. Löwe, S.V. Albers, Nature Microbiology 9 (2024) 698–711.","chicago":"Nußbaum, Phillip, Danguole Kureisaite-Ciziene, Dom Bellini, Chris Van Der Does, Marko Kojic, Najwa Taib, Anna Yeates, et al. “Proteins Containing Photosynthetic Reaction Centre Domains Modulate FtsZ-Based Archaeal Cell Division.” <i>Nature Microbiology</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41564-024-01600-5\">https://doi.org/10.1038/s41564-024-01600-5</a>.","ieee":"P. Nußbaum <i>et al.</i>, “Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division,” <i>Nature Microbiology</i>, vol. 9, no. 3. Springer Nature, pp. 698–711, 2024.","mla":"Nußbaum, Phillip, et al. “Proteins Containing Photosynthetic Reaction Centre Domains Modulate FtsZ-Based Archaeal Cell Division.” <i>Nature Microbiology</i>, vol. 9, no. 3, Springer Nature, 2024, pp. 698–711, doi:<a href=\"https://doi.org/10.1038/s41564-024-01600-5\">10.1038/s41564-024-01600-5</a>.","ama":"Nußbaum P, Kureisaite-Ciziene D, Bellini D, et al. Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division. <i>Nature Microbiology</i>. 2024;9(3):698-711. doi:<a href=\"https://doi.org/10.1038/s41564-024-01600-5\">10.1038/s41564-024-01600-5</a>","apa":"Nußbaum, P., Kureisaite-Ciziene, D., Bellini, D., Van Der Does, C., Kojic, M., Taib, N., … Albers, S. V. (2024). Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division. <i>Nature Microbiology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41564-024-01600-5\">https://doi.org/10.1038/s41564-024-01600-5</a>"},"publication_identifier":{"eissn":["2058-5276"]},"publication_status":"published","publisher":"Springer Nature","abstract":[{"lang":"eng","text":"Cell division in all domains of life requires the orchestration of many proteins, but in Archaea most of the machinery remains poorly characterized. Here we investigate the FtsZ-based cell division mechanism in Haloferax volcanii and find proteins containing photosynthetic reaction centre (PRC) barrel domains that play an essential role in archaeal cell division. We rename these proteins cell division protein B 1 (CdpB1) and CdpB2. Depletions and deletions in their respective genes cause severe cell division defects, generating drastically enlarged cells. Fluorescence microscopy of tagged FtsZ1, FtsZ2 and SepF in CdpB1 and CdpB2 mutant strains revealed an unusually disordered divisome that is not organized into a distinct ring-like structure. Biochemical analysis shows that SepF forms a tripartite complex with CdpB1/2 and crystal structures suggest that these two proteins might form filaments, possibly aligning SepF and the FtsZ2 ring during cell division. Overall our results indicate that PRC-domain proteins play essential roles in FtsZ-based cell division in Archaea."}],"oa_version":"None","acknowledgement":"We thank X. Ye (ISTA) for providing the His–SUMO expression plasmid pSVA13429. pCDB302 was a gift from C. Bahl (Addgene plasmid number 113673; http://n2t.net/addgene:113673; RRID Addgene_113673). We thank B. Ahsan, G. Sharov, G. Cannone and S. Chen from the Medical Research Council (MRC) LMB Electron Microscopy Facility for help and support. We thank Scientific Computing at the MRC LMB for their support. We thank L. Trübestein and N. Krasnici of the protein service unit of the ISTA Lab Support Facility for help with the SEC coupled with multi-angle light scattering experiments. We thank D. Grohmann and R. Reichelt from the Archaea Centre at the University of Regensburg for providing the P. furiosus cell material. P.N. and S.-V.A. were supported by a Momentum grant from the Volkswagen (VW) Foundation (grant number 94933). D.K.-C. and D.B. were supported by the VW Stiftung ‘Life?’ programme (to J.L.; grant number Az 96727) and by the MRC, as part of UK Research and Innovation (UKRI), MRC file reference number U105184326 (to J.L.). N.T. and S.G. acknowledge support from the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence ‘Integrative Biology of Emerging Infectious Diseases’ (grant number ANR-10-LABX-62-IBEID), and the computational and storage services (Maestro cluster) provided by the IT department at Institut Pasteur. M.K. and M.L. were supported by the Austrian Science Fund (FWF) Stand-Alone P34607. For the purpose of open access, the MRC Laboratory of Molecular Biology has applied a CC BY public copyright licence to any author accepted manuscript version arising.","doi":"10.1038/s41564-024-01600-5","quality_controlled":"1","volume":9,"year":"2024","status":"public","date_published":"2024-03-04T00:00:00Z","_id":"15118","isi":1,"pmid":1,"language":[{"iso":"eng"}],"department":[{"_id":"MaLo"}],"scopus_import":"1","acknowledged_ssus":[{"_id":"LifeSc"}],"article_processing_charge":"No","project":[{"name":"In vitro reconstitution of bacterial cell division","grant_number":"P34607","_id":"fc38323b-9c52-11eb-aca3-ff8afb4a011d"}]},{"doi":"10.21942/UVA.24829896","month":"02","year":"2024","status":"public","extern":"1","fulldoi":"https://doi.org/10.21942/UVA.24829896","date_published":"2024-02-14T00:00:00Z","date_updated":"2025-09-04T13:03:56Z","_id":"15126","citation":{"ieee":"G. Giubertoni and S. Woutersen, “Dataset Collagen Self Assembly in H2O and D2O.” Figshare, 2024.","mla":"Giubertoni, G., and S. Woutersen. <i>Dataset Collagen Self Assembly in H2O and D2O</i>. Figshare, 2024, doi:<a href=\"https://doi.org/10.21942/UVA.24829896\">10.21942/UVA.24829896</a>.","chicago":"Giubertoni, G., and S. Woutersen. “Dataset Collagen Self Assembly in H2O and D2O.” Figshare, 2024. <a href=\"https://doi.org/10.21942/UVA.24829896\">https://doi.org/10.21942/UVA.24829896</a>.","apa":"Giubertoni, G., &#38; Woutersen, S. (2024). Dataset Collagen Self Assembly in H2O and D2O. Figshare. <a href=\"https://doi.org/10.21942/UVA.24829896\">https://doi.org/10.21942/UVA.24829896</a>","ama":"Giubertoni G, Woutersen S. Dataset Collagen Self Assembly in H2O and D2O. 2024. doi:<a href=\"https://doi.org/10.21942/UVA.24829896\">10.21942/UVA.24829896</a>","short":"G. Giubertoni, S. Woutersen, (2024).","ista":"Giubertoni G, Woutersen S. 2024. Dataset Collagen Self Assembly in H2O and D2O, Figshare, <a href=\"https://doi.org/10.21942/UVA.24829896\">10.21942/UVA.24829896</a>."},"date_created":"2024-03-19T10:47:16Z","publisher":"Figshare","has_accepted_license":"1","abstract":[{"lang":"eng","text":"This zip file contains data, and analysis for the paper \"Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration\"."}],"title":"Dataset Collagen Self Assembly in H2O and D2O","main_file_link":[{"url":"https://doi.org/10.21942/UVA.24829896","open_access":"1"}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa":1,"article_processing_charge":"No","related_material":{"record":[{"status":"public","id":"15116","relation":"used_in_publication"}]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"research_data_reference","author":[{"first_name":"G.","last_name":"Giubertoni","full_name":"Giubertoni, G."},{"last_name":"Woutersen","first_name":"S.","full_name":"Woutersen, S."}],"ddc":["550"],"day":"14"},{"abstract":[{"text":"The extracellular matrix (ECM) serves as a scaffold for cells and plays an essential role in regulating numerous cellular processes, including cell migration and proliferation. Due to limitations in specimen preparation for conventional room-temperature electron microscopy, we lack structural knowledge on how ECM components are secreted, remodeled, and interact with surrounding cells. We have developed a 3D-ECM platform compatible with sample thinning by cryo-focused ion beam milling, the lift-out extraction procedure, and cryo-electron tomography. Our workflow implements cell-derived matrices (CDMs) grown on EM grids, resulting in a versatile tool closely mimicking ECM environments. This allows us to visualize ECM for the first time in its hydrated, native context. Our data reveal an intricate network of extracellular fibers, their positioning relative to matrix-secreting cells, and previously unresolved structural entities. Our workflow and results add to the structural atlas of the ECM, providing novel insights into its secretion and assembly.","lang":"eng"}],"corr_author":"1","oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"intvolume":"       223","citation":{"ista":"Zens B, Fäßler F, Hansen J, Hauschild R, Datler J, Hodirnau V-V, Zheden V, Alanko JH, Sixt MK, Schur FK. 2024. Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. Journal of Cell Biology. 223(6), e202309125.","short":"B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).","apa":"Zens, B., Fäßler, F., Hansen, J., Hauschild, R., Datler, J., Hodirnau, V.-V., … Schur, F. K. (2024). Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. <i>Journal of Cell Biology</i>. Rockefeller University Press. <a href=\"https://doi.org/10.1083/jcb.202309125\">https://doi.org/10.1083/jcb.202309125</a>","ama":"Zens B, Fäßler F, Hansen J, et al. Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. <i>Journal of Cell Biology</i>. 2024;223(6). doi:<a href=\"https://doi.org/10.1083/jcb.202309125\">10.1083/jcb.202309125</a>","chicago":"Zens, Bettina, Florian Fäßler, Jesse Hansen, Robert Hauschild, Julia Datler, Victor-Valentin Hodirnau, Vanessa Zheden, Jonna H Alanko, Michael K Sixt, and Florian KM Schur. “Lift-out Cryo-FIBSEM and Cryo-ET Reveal the Ultrastructural Landscape of Extracellular Matrix.” <i>Journal of Cell Biology</i>. Rockefeller University Press, 2024. <a href=\"https://doi.org/10.1083/jcb.202309125\">https://doi.org/10.1083/jcb.202309125</a>.","mla":"Zens, Bettina, et al. “Lift-out Cryo-FIBSEM and Cryo-ET Reveal the Ultrastructural Landscape of Extracellular Matrix.” <i>Journal of Cell Biology</i>, vol. 223, no. 6, e202309125, Rockefeller University Press, 2024, doi:<a href=\"https://doi.org/10.1083/jcb.202309125\">10.1083/jcb.202309125</a>.","ieee":"B. Zens <i>et al.</i>, “Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix,” <i>Journal of Cell Biology</i>, vol. 223, no. 6. Rockefeller University Press, 2024."},"publication_identifier":{"issn":["0021-9525"],"eissn":["1540-8140"]},"publisher":"Rockefeller University Press","publication_status":"published","ec_funded":1,"year":"2024","status":"public","date_published":"2024-03-20T00:00:00Z","_id":"15146","acknowledgement":"Open Access funding provided by IST Austria. We thank Armel Nicolas and his team at the ISTA proteomics facility, Alois Schloegl, Stefano Elefante, and colleagues at the ISTA Scientific Computing facility, Tommaso Constanzo and Ludek Lovicar at the Electron Microsocpy Facility (EMF), and Thomas Menner at the Miba Machine shop for their support. We also thank Wanda Kukulski (University of Bern) as well as Darío Porley, Andreas Thader, and other members of the Schur group for helpful discussions. Matt Swulius and Jessica Heebner provided great support in using Dragonfly. We thank Dorotea Fracciolla (Art & Science) for support in figure illustration.\r\n\r\nThis research was supported by the Scientific Service Units of ISTA through resources provided by Scientific Computing, the Lab Support Facility, and the Electron Microscopy Facility. We acknowledge funding support from the following sources: Austrian Science Fund (FWF) grant P33367 (to F.K.M. Schur), the Federation of European Biochemical Societies (to F.K.M. Schur), Niederösterreich (NÖ) Fonds (to B. Zens), FWF grant E435 (to J.M. Hansen), European Research Council under the European Union’s Horizon 2020 research (grant agreement No. 724373) (to M. Sixt), and Jenny and Antti Wihuri Foundation (to J. Alanko). This publication has been made possible in part by CZI grant DAF2021-234754 and grant DOI https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation (to F.K.M. Schur).","doi":"10.1083/jcb.202309125","volume":223,"quality_controlled":"1","ddc":["570"],"isi":1,"department":[{"_id":"FlSc"},{"_id":"MiSi"},{"_id":"Bio"},{"_id":"EM-Fac"}],"scopus_import":"1","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"ScienComp"},{"_id":"EM-Fac"},{"_id":"M-Shop"}],"oa":1,"article_number":"e202309125","project":[{"_id":"9B954C5C-BA93-11EA-9121-9846C619BF3A","name":"Structure and isoform diversity of the Arp2/3 complex","grant_number":"P33367"},{"_id":"7bd318a1-9f16-11ee-852c-cc9217763180","grant_number":"E435","name":"In Situ Actin Structures via Hybrid Cryo-electron Microscopy"},{"_id":"25FE9508-B435-11E9-9278-68D0E5697425","grant_number":"724373","name":"Cellular Navigation Along Spatial Gradients","call_identifier":"H2020"},{"name":"NÖ-Fonds Preis für die Jungforscherin des Jahres am IST Austria","_id":"059B463C-7A3F-11EA-A408-12923DDC885E"},{"_id":"2615199A-B435-11E9-9278-68D0E5697425","name":"Spatiotemporal regulation of chemokine-induced signalling in leukocyte chemotaxis","grant_number":"21317"},{"_id":"62909c6f-2b32-11ec-9570-e1476aab5308","name":"CryoMinflux-guided in-situ visual proteomics and structure determination","grant_number":"CZI01"}],"article_processing_charge":"Yes (via OA deal)","pmid":1,"language":[{"iso":"eng"}],"has_accepted_license":"1","title":"Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix","date_created":"2024-03-21T06:45:51Z","publication":"Journal of Cell Biology","file_date_updated":"2024-03-25T12:52:04Z","date_updated":"2025-09-04T13:17:16Z","fulldoi":"https://doi.org/10.1083/jcb.202309125","issue":"6","month":"03","day":"20","author":[{"full_name":"Zens, Bettina","orcid":"0000-0002-9561-1239","id":"45FD126C-F248-11E8-B48F-1D18A9856A87","first_name":"Bettina","last_name":"Zens"},{"id":"404F5528-F248-11E8-B48F-1D18A9856A87","full_name":"Fäßler, Florian","orcid":"0000-0001-7149-769X","last_name":"Fäßler","first_name":"Florian"},{"id":"1063c618-6f9b-11ec-9123-f912fccded63","orcid":"0000-0001-7967-2085","full_name":"Hansen, Jesse","last_name":"Hansen","first_name":"Jesse"},{"first_name":"Robert","last_name":"Hauschild","orcid":"0000-0001-9843-3522","full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Datler","first_name":"Julia","id":"3B12E2E6-F248-11E8-B48F-1D18A9856A87","full_name":"Datler, Julia","orcid":"0000-0002-3616-8580"},{"first_name":"Victor-Valentin","last_name":"Hodirnau","id":"3661B498-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3904-947X","full_name":"Hodirnau, Victor-Valentin"},{"last_name":"Zheden","first_name":"Vanessa","id":"39C5A68A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9438-4783","full_name":"Zheden, Vanessa"},{"last_name":"Alanko","first_name":"Jonna H","orcid":"0000-0002-7698-3061","full_name":"Alanko, Jonna H","id":"2CC12E8C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Michael K","last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Schur","first_name":"Florian KM","orcid":"0000-0003-4790-8078","full_name":"Schur, Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","external_id":{"pmid":["38506714"],"isi":["001264190100001"]},"file":[{"relation":"main_file","access_level":"open_access","creator":"dernst","success":1,"file_size":11907016,"file_name":"2024_JCB_Zens.pdf","date_updated":"2024-03-25T12:52:04Z","date_created":"2024-03-25T12:52:04Z","file_id":"15188","content_type":"application/pdf","checksum":"90d1984a93660735e506c2a304bc3f73"}],"article_type":"original"},{"title":"Decompositions into two linear forests of bounded lengths","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2301.11615"}],"publication":"Discrete Mathematics","date_created":"2024-03-24T23:00:58Z","date_updated":"2025-09-04T13:10:26Z","fulldoi":"https://doi.org/10.1016/j.disc.2024.113962","issue":"6","month":"06","arxiv":1,"author":[{"full_name":"Campbell, Rutger","first_name":"Rutger","last_name":"Campbell"},{"full_name":"Hörsch, Florian","first_name":"Florian","last_name":"Hörsch"},{"last_name":"Moore","first_name":"Benjamin","full_name":"Moore, Benjamin","id":"6dc1a1be-bf1c-11ed-8d2b-d044840f49d6"}],"day":"01","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","external_id":{"isi":["001226893800001"],"arxiv":["2301.11615"]},"article_type":"original","corr_author":"1","abstract":[{"text":"For some k∈Z≥0∪{∞}, we call a linear forest k-bounded if each of its components has at most k edges. We will say a (k,ℓ)-bounded linear forest decomposition of a graph G is a partition of E(G) into the edge sets of two linear forests Fk,Fℓ where Fk is k-bounded and Fℓ is ℓ-bounded. We show that the problem of deciding whether a given graph has such a decomposition is NP-complete if both k and ℓ are at least 2, NP-complete if k≥9 and ℓ=1, and is in P for (k,ℓ)=(2,1). Before this, the only known NP-complete cases were the (2,2) and (3,3) cases. Our hardness result answers a question of Bermond et al. from 1984. We also show that planar graphs of girth at least nine decompose into a linear forest and a matching, which in particular is stronger than 3-edge-colouring such graphs.","lang":"eng"}],"oa_version":"Preprint","intvolume":"       347","citation":{"ama":"Campbell R, Hörsch F, Moore B. Decompositions into two linear forests of bounded lengths. <i>Discrete Mathematics</i>. 2024;347(6). doi:<a href=\"https://doi.org/10.1016/j.disc.2024.113962\">10.1016/j.disc.2024.113962</a>","apa":"Campbell, R., Hörsch, F., &#38; Moore, B. (2024). Decompositions into two linear forests of bounded lengths. <i>Discrete Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.disc.2024.113962\">https://doi.org/10.1016/j.disc.2024.113962</a>","mla":"Campbell, Rutger, et al. “Decompositions into Two Linear Forests of Bounded Lengths.” <i>Discrete Mathematics</i>, vol. 347, no. 6, 113962, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.disc.2024.113962\">10.1016/j.disc.2024.113962</a>.","chicago":"Campbell, Rutger, Florian Hörsch, and Benjamin Moore. “Decompositions into Two Linear Forests of Bounded Lengths.” <i>Discrete Mathematics</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.disc.2024.113962\">https://doi.org/10.1016/j.disc.2024.113962</a>.","ieee":"R. Campbell, F. Hörsch, and B. Moore, “Decompositions into two linear forests of bounded lengths,” <i>Discrete Mathematics</i>, vol. 347, no. 6. Elsevier, 2024.","ista":"Campbell R, Hörsch F, Moore B. 2024. Decompositions into two linear forests of bounded lengths. Discrete Mathematics. 347(6), 113962.","short":"R. Campbell, F. Hörsch, B. Moore, Discrete Mathematics 347 (2024)."},"publication_identifier":{"issn":["0012-365X"]},"publication_status":"published","publisher":"Elsevier","year":"2024","status":"public","date_published":"2024-06-01T00:00:00Z","_id":"15163","acknowledgement":"We wish to thank Dániel Marx and András Sebő for making us aware of the results in [8] and some clarifications on them.","doi":"10.1016/j.disc.2024.113962","quality_controlled":"1","volume":347,"isi":1,"scopus_import":"1","department":[{"_id":"MaKw"}],"oa":1,"article_number":"113962","article_processing_charge":"No","language":[{"iso":"eng"}]},{"volume":51,"quality_controlled":"1","APC_amount":"1470 EUR","acknowledgement":"The author gratefully acknowledges ISTA for supporting this research through funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Project CLUSTER, grant agreement No. 805041).","doi":"10.1029/2023GL106569","date_published":"2024-03-16T00:00:00Z","_id":"15165","year":"2024","status":"public","publication_identifier":{"eissn":["1944-8007"],"issn":["0094-8276"]},"ec_funded":1,"publication_status":"published","DOAJ_listed":"1","publisher":"Wiley","intvolume":"        51","citation":{"ista":"GOSWAMI BB. 2024. A pre-monsoon signal of false alarms of Indian monsoon droughts. Geophysical Research Letters. 51(5), e2023GL106569.","short":"B.B. GOSWAMI, Geophysical Research Letters 51 (2024).","ama":"GOSWAMI BB. A pre-monsoon signal of false alarms of Indian monsoon droughts. <i>Geophysical Research Letters</i>. 2024;51(5). doi:<a href=\"https://doi.org/10.1029/2023GL106569\">10.1029/2023GL106569</a>","apa":"GOSWAMI, B. B. (2024). A pre-monsoon signal of false alarms of Indian monsoon droughts. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2023GL106569\">https://doi.org/10.1029/2023GL106569</a>","ieee":"B. B. GOSWAMI, “A pre-monsoon signal of false alarms of Indian monsoon droughts,” <i>Geophysical Research Letters</i>, vol. 51, no. 5. Wiley, 2024.","mla":"GOSWAMI, BIDYUT B. “A Pre-Monsoon Signal of False Alarms of Indian Monsoon Droughts.” <i>Geophysical Research Letters</i>, vol. 51, no. 5, e2023GL106569, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023GL106569\">10.1029/2023GL106569</a>.","chicago":"GOSWAMI, BIDYUT B. “A Pre-Monsoon Signal of False Alarms of Indian Monsoon Droughts.” <i>Geophysical Research Letters</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023GL106569\">https://doi.org/10.1029/2023GL106569</a>."},"oa_version":"Published Version","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"abstract":[{"text":"Current knowledge suggests a drought Indian monsoon (perhaps a severe one) when the El Nino Southern Oscillation and Pacific Decadal Oscillation each exhibit positive phases (a joint positive phase). For the monsoons, which are exceptions in this regard, we found northeast India often gets excess pre-monsoon rainfall. Further investigation reveals that this excess pre-monsoon rainfall is produced by the interaction of the large-scale circulation associated with the joint phase with the mountains in northeast India. We posit that a warmer troposphere, a consequence of excess rainfall over northeast India, drives a stronger monsoon circulation and enhances monsoon rainfall over central India. Hence, we argue that pre-monsoon rainfall over northeast India can be used for seasonal monsoon rainfall prediction over central India. Most importantly, its predictive value is at its peak when the Pacific Ocean exhibits a joint positive phase and the threat of extreme drought monsoon looms over India.","lang":"eng"}],"corr_author":"1","language":[{"iso":"eng"}],"project":[{"grant_number":"805041","call_identifier":"H2020","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","_id":"629205d8-2b32-11ec-9570-e1356ff73576"}],"article_processing_charge":"Yes","scopus_import":"1","department":[{"_id":"CaMu"}],"oa":1,"article_number":"e2023GL106569","isi":1,"ddc":["550"],"issue":"5","month":"03","date_updated":"2025-09-04T13:11:41Z","fulldoi":"https://doi.org/10.1029/2023GL106569","file_date_updated":"2024-03-25T08:36:00Z","date_created":"2024-03-24T23:00:58Z","publication":"Geophysical Research Letters","OA_place":"publisher","has_accepted_license":"1","title":"A pre-monsoon signal of false alarms of Indian monsoon droughts","article_type":"original","file":[{"date_created":"2024-03-25T08:36:00Z","content_type":"application/pdf","checksum":"243bd966aca968ec7d9e474af8639f8d","file_id":"15178","relation":"main_file","access_level":"open_access","creator":"dernst","success":1,"date_updated":"2024-03-25T08:36:00Z","file_size":2887134,"file_name":"2024_GeophysResLetters_Goswami.pdf"}],"external_id":{"isi":["001181635700001"]},"OA_type":"gold","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","author":[{"last_name":"Goswami","first_name":"Bidyut B","id":"3a4ac09c-6d61-11ec-bf66-884cde66b64b","full_name":"Goswami, Bidyut B","orcid":"0000-0001-8602-3083"}],"day":"16"},{"pmid":1,"language":[{"iso":"eng"}],"department":[{"_id":"MaIb"}],"scopus_import":"1","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"article_processing_charge":"No","isi":1,"doi":"10.1126/science.ado4077","acknowledgement":"The authors thank the Werner-Siemens-Stiftung and the Institute of Science and Technology Austria for financial support.","quality_controlled":"1","volume":383,"status":"public","year":"2024","_id":"15166","date_published":"2024-03-14T00:00:00Z","citation":{"ama":"Jakhar N, Ibáñez M. Electron highways are cooler. <i>Science</i>. 2024;383(6688):1184. doi:<a href=\"https://doi.org/10.1126/science.ado4077\">10.1126/science.ado4077</a>","apa":"Jakhar, N., &#38; Ibáñez, M. (2024). Electron highways are cooler. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.ado4077\">https://doi.org/10.1126/science.ado4077</a>","ieee":"N. Jakhar and M. Ibáñez, “Electron highways are cooler,” <i>Science</i>, vol. 383, no. 6688. American Association for the Advancement of Science, p. 1184, 2024.","chicago":"Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” <i>Science</i>. 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These corrections demonstrate divergent behavior in the limit of large impurity momentum. We show the fundamental processes responsible for these logarithmically divergent terms. We study the problem in the general case without any assumptions regarding the fermion-fermion interactions in the bath. We show that the divergent term can be summed up to all orders in the Fermi-Fermi interaction and that the resulting expression is equivalent to the one obtained in the few-body calculation. Finally, we provide a perturbative calculation to the second order in the Fermi-Fermi interaction, and we show the diagrams responsible for these terms."}],"publication_status":"published","publisher":"American Physical Society","publication_identifier":{"eissn":["2469-9934"],"issn":["2469-9926"]},"citation":{"short":"R. Al Hyder, F. Chevy, X. Leyronas, Physical Review A 109 (2024).","ista":"Al Hyder R, Chevy F, Leyronas X. 2024. Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. Physical Review A. 109(3), 033315.","ama":"Al Hyder R, Chevy F, Leyronas X. Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. <i>Physical Review A</i>. 2024;109(3). doi:<a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">10.1103/PhysRevA.109.033315</a>","apa":"Al Hyder, R., Chevy, F., &#38; Leyronas, X. (2024). Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy. <i>Physical Review A</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">https://doi.org/10.1103/PhysRevA.109.033315</a>","mla":"Al Hyder, Ragheed, et al. “Exploring Beyond-Mean-Field Logarithmic Divergences in Fermi-Polaron Energy.” <i>Physical Review A</i>, vol. 109, no. 3, 033315, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">10.1103/PhysRevA.109.033315</a>.","ieee":"R. Al Hyder, F. Chevy, and X. Leyronas, “Exploring beyond-mean-field logarithmic divergences in Fermi-polaron energy,” <i>Physical Review A</i>, vol. 109, no. 3. American Physical Society, 2024.","chicago":"Al Hyder, Ragheed, F. Chevy, and X. Leyronas. “Exploring Beyond-Mean-Field Logarithmic Divergences in Fermi-Polaron Energy.” <i>Physical Review A</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevA.109.033315\">https://doi.org/10.1103/PhysRevA.109.033315</a>."},"intvolume":"       109","article_processing_charge":"No","article_number":"033315","oa":1,"scopus_import":"1","department":[{"_id":"MiLe"}],"language":[{"iso":"eng"}],"isi":1},{"publication":"Astrophysical Journal","date_created":"2024-03-24T23:00:59Z","title":"UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z > 5","has_accepted_license":"1","month":"03","file_date_updated":"2024-03-25T08:02:43Z","fulldoi":"https://doi.org/10.3847/1538-4357/ad1e5f","date_updated":"2025-09-04T13:09:41Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","arxiv":1,"day":"01","author":[{"full_name":"Greene, Jenny E.","last_name":"Greene","first_name":"Jenny E."},{"last_name":"Labbe","first_name":"Ivo","full_name":"Labbe, Ivo"},{"full_name":"Goulding, Andy D.","first_name":"Andy D.","last_name":"Goulding"},{"full_name":"Furtak, Lukas J.","last_name":"Furtak","first_name":"Lukas J."},{"first_name":"Iryna","last_name":"Chemerynska","full_name":"Chemerynska, Iryna"},{"full_name":"Kokorev, Vasily","last_name":"Kokorev","first_name":"Vasily"},{"full_name":"Dayal, Pratika","first_name":"Pratika","last_name":"Dayal"},{"full_name":"Volonteri, Marta","last_name":"Volonteri","first_name":"Marta"},{"first_name":"Christina C.","last_name":"Williams","full_name":"Williams, Christina C."},{"full_name":"Wang, Bingjie","first_name":"Bingjie","last_name":"Wang"},{"full_name":"Setton, David J.","first_name":"David J.","last_name":"Setton"},{"full_name":"Burgasser, Adam J.","first_name":"Adam J.","last_name":"Burgasser"},{"full_name":"Bezanson, Rachel","first_name":"Rachel","last_name":"Bezanson"},{"full_name":"Atek, Hakim","last_name":"Atek","first_name":"Hakim"},{"full_name":"Brammer, Gabriel","first_name":"Gabriel","last_name":"Brammer"},{"full_name":"Cutler, Sam E.","first_name":"Sam E.","last_name":"Cutler"},{"full_name":"Feldmann, Robert","first_name":"Robert","last_name":"Feldmann"},{"full_name":"Fujimoto, Seiji","first_name":"Seiji","last_name":"Fujimoto"},{"last_name":"Glazebrook","first_name":"Karl","full_name":"Glazebrook, Karl"},{"last_name":"De Graaff","first_name":"Anna","full_name":"De Graaff, Anna"},{"full_name":"Khullar, Gourav","last_name":"Khullar","first_name":"Gourav"},{"full_name":"Leja, Joel","last_name":"Leja","first_name":"Joel"},{"full_name":"Marchesini, Danilo","last_name":"Marchesini","first_name":"Danilo"},{"first_name":"Michael V.","last_name":"Maseda","full_name":"Maseda, Michael V."},{"orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee"},{"full_name":"Miller, Tim B.","last_name":"Miller","first_name":"Tim B."},{"full_name":"Naidu, Rohan P.","first_name":"Rohan P.","last_name":"Naidu"},{"full_name":"Nanayakkara, Themiya","first_name":"Themiya","last_name":"Nanayakkara"},{"full_name":"Oesch, Pascal A.","last_name":"Oesch","first_name":"Pascal A."},{"last_name":"Pan","first_name":"Richard","full_name":"Pan, Richard"},{"last_name":"Papovich","first_name":"Casey","full_name":"Papovich, Casey"},{"last_name":"Price","first_name":"Sedona H.","full_name":"Price, Sedona H."},{"first_name":"Pieter","last_name":"Van Dokkum","full_name":"Van Dokkum, Pieter"},{"last_name":"Weaver","first_name":"John R.","full_name":"Weaver, John R."},{"first_name":"Katherine E.","last_name":"Whitaker","full_name":"Whitaker, Katherine E."},{"last_name":"Zitrin","first_name":"Adi","full_name":"Zitrin, Adi"}],"file":[{"file_name":"2024_AstrophysicalJourn_Greene.pdf","file_size":2700137,"date_updated":"2024-03-25T08:02:43Z","success":1,"creator":"dernst","relation":"main_file","access_level":"open_access","content_type":"application/pdf","checksum":"389a880e176799d5c062ea7cb82d08c9","file_id":"15176","date_created":"2024-03-25T08:02:43Z"}],"article_type":"original","external_id":{"isi":["001184746500001"],"arxiv":["2309.05714"]},"citation":{"short":"J.E. Greene, I. Labbe, A.D. Goulding, L.J. Furtak, I. Chemerynska, V. Kokorev, P. Dayal, M. Volonteri, C.C. Williams, B. Wang, D.J. Setton, A.J. Burgasser, R. Bezanson, H. Atek, G. Brammer, S.E. Cutler, R. Feldmann, S. Fujimoto, K. Glazebrook, A. De Graaff, G. Khullar, J. Leja, D. Marchesini, M.V. Maseda, J.J. Matthee, T.B. Miller, R.P. Naidu, T. Nanayakkara, P.A. Oesch, R. Pan, C. Papovich, S.H. Price, P. Van Dokkum, J.R. Weaver, K.E. Whitaker, A. Zitrin, Astrophysical Journal 964 (2024).","ista":"Greene JE, Labbe I, Goulding AD, Furtak LJ, Chemerynska I, Kokorev V, Dayal P, Volonteri M, Williams CC, Wang B, Setton DJ, Burgasser AJ, Bezanson R, Atek H, Brammer G, Cutler SE, Feldmann R, Fujimoto S, Glazebrook K, De Graaff A, Khullar G, Leja J, Marchesini D, Maseda MV, Matthee JJ, Miller TB, Naidu RP, Nanayakkara T, Oesch PA, Pan R, Papovich C, Price SH, Van Dokkum P, Weaver JR, Whitaker KE, Zitrin A. 2024. UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. Astrophysical Journal. 964, 39.","apa":"Greene, J. E., Labbe, I., Goulding, A. D., Furtak, L. J., Chemerynska, I., Kokorev, V., … Zitrin, A. (2024). UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. <i>Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">https://doi.org/10.3847/1538-4357/ad1e5f</a>","ama":"Greene JE, Labbe I, Goulding AD, et al. UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5. <i>Astrophysical Journal</i>. 2024;964. doi:<a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">10.3847/1538-4357/ad1e5f</a>","chicago":"Greene, Jenny E., Ivo Labbe, Andy D. Goulding, Lukas J. Furtak, Iryna Chemerynska, Vasily Kokorev, Pratika Dayal, et al. “UNCOVER Spectroscopy Confirms the Surprising Ubiquity of Active Galactic Nuclei in Red Sources at z &#62; 5.” <i>Astrophysical Journal</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">https://doi.org/10.3847/1538-4357/ad1e5f</a>.","mla":"Greene, Jenny E., et al. “UNCOVER Spectroscopy Confirms the Surprising Ubiquity of Active Galactic Nuclei in Red Sources at z &#62; 5.” <i>Astrophysical Journal</i>, vol. 964, 39, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad1e5f\">10.3847/1538-4357/ad1e5f</a>.","ieee":"J. E. Greene <i>et al.</i>, “UNCOVER spectroscopy confirms the surprising ubiquity of active galactic nuclei in red sources at z &#62; 5,” <i>Astrophysical Journal</i>, vol. 964. IOP Publishing, 2024."},"intvolume":"       964","publication_status":"published","publisher":"IOP Publishing","DOAJ_listed":"1","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"abstract":[{"text":"The James Webb Space Telescope is revealing a new population of dust-reddened broad-line active galactic nuclei (AGN) at redshifts z ≳ 5. Here we present deep NIRSpec/Prism spectroscopy from the Cycle 1 Treasury program Ultradeep NIRSpec and NIRCam ObserVations before the Epoch of Reionization (UNCOVER) of 15 AGN candidates selected to be compact, with red continua in the rest-frame optical but with blue slopes in the UV. From NIRCam photometry alone, they could have been dominated by dusty star formation or an AGN. Here we show that the majority of the compact red sources in UNCOVER are dust-reddened AGN: 60% show definitive evidence for broad-line Hα with a FWHM > 2000 km s −1, 20% of the current data are inconclusive, and 20% are brown dwarf stars. We propose an updated photometric criterion to select red z > 5 AGN that excludes brown dwarfs and is expected to yield >80% AGN. Remarkably, among all zphot > 5 galaxies with F277W – F444W > 1 in UNCOVER at least 33% are AGN regardless of compactness, climbing to at least 80% AGN for sources with F277W – F444W > 1.6. The confirmed AGN have black hole masses of 107–109M⊙. While their UV luminosities (−16 > MUV > −20 AB mag) are low compared to UV-selected AGN at these epochs, consistent with percent-level scattered AGN light or low levels of unobscured star formation, the inferred bolometric luminosities are typical of 107–109M⊙ black holes radiating at ∼10%–40% the Eddington limit. The number densities are surprisingly high at ∼10−5 Mpc−3 mag−1, 100 times more common than the faintest UV-selected quasars, while accounting for ∼1% of the UV-selected galaxies. While their UV faintness suggests they may not contribute strongly to reionization, their ubiquity poses challenges to models of black hole growth.","lang":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","doi":"10.3847/1538-4357/ad1e5f","acknowledgement":"J.E.G. and A.D.G acknowledge support from NSF/AAG grant No. 1007094, and J.E.G. also acknowledges support from NSF/AAG grant No. 1007052. A.Z. acknowledges support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Ministry of Science & Technology of Israel. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant No. 140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (\"ODIN\") and from the European Commission's and University of Groningen's CO-FUND Rosalind Franklin program. K.G. and T.N. acknowledge support from Australian Research Council Laureate Fellowship FL180100060. H.A. and I.C. acknowledge support from CNES, focused on the JWST mission, and the Programme National Cosmology and Galaxies (PNCG) of CNRS/INSU with INP and IN2P3, cofunded by CEA and CNES. R.P.N. acknowledges funding from JWST programs GO-1933 and GO-2279. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. The research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation. B.W. acknowledges support from JWST-GO-02561.022-A. A.J.B. acknowledges funding support from NASA/ADAP grant 21-ADAP21-0187. Support for this work was provided by The Brinson Foundation through a Brinson Prize Fellowship grant. R.P.N. acknowledges support for this work provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. C.P. thanks Marsha and Ralph Schilling for the generous support of this research.","volume":964,"quality_controlled":"1","status":"public","year":"2024","_id":"15170","date_published":"2024-03-01T00:00:00Z","isi":1,"ddc":["550"],"language":[{"iso":"eng"}],"oa":1,"article_number":"39","department":[{"_id":"JoMa"}],"scopus_import":"1","article_processing_charge":"Yes"},{"article_processing_charge":"Yes (via OA deal)","project":[{"_id":"0aacfa84-070f-11eb-9043-d7eb2c709234","call_identifier":"H2020","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning.","grant_number":"819603"}],"oa":1,"scopus_import":"1","department":[{"_id":"TiVo"}],"language":[{"iso":"eng"}],"pmid":1,"ddc":["570"],"isi":1,"_id":"15171","date_published":"2024-05-01T00:00:00Z","status":"public","year":"2024","volume":27,"quality_controlled":"1","doi":"10.1038/s41593-024-01597-4","acknowledgement":"We thank C. Currin, B. Podlaski and the members of the Vogels group for fruitful discussions. E.J.A. and T.P.V. were supported by a Research Project Grant from the Leverhulme Trust (RPG-2016-446; TPV), a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society (WT100000; T.P.V.), a Wellcome Trust Senior Research Fellowship (214316/Z/18/Z; T.P.V.) and a European Research Council Consolidator Grant (SYNAPSEEK, 819603; T.P.V.). For the purpose of open access, the authors have applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. Open access funding provided by University of Basel.","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","abstract":[{"lang":"eng","text":"The brain’s functionality is developed and maintained through synaptic plasticity. As synapses undergo plasticity, they also affect each other. The nature of such ‘co-dependency’ is difficult to disentangle experimentally, because multiple synapses must be monitored simultaneously. To help understand the experimentally observed phenomena, we introduce a framework that formalizes synaptic co-dependency between different connection types. The resulting model explains how inhibition can gate excitatory plasticity while neighboring excitatory–excitatory interactions determine the strength of long-term potentiation. Furthermore, we show how the interplay between excitatory and inhibitory synapses can account for the quick rise and long-term stability of a variety of synaptic weight profiles, such as orientation tuning and dendritic clustering of co-active synapses. In recurrent neuronal networks, co-dependent plasticity produces rich and stable motor cortex-like dynamics with high input sensitivity. Our results suggest an essential role for the neighborly synaptic interaction during learning, connecting micro-level physiology with network-wide phenomena."}],"publication_status":"published","publisher":"Springer Nature","ec_funded":1,"publication_identifier":{"issn":["1097-6256"],"eissn":["1546-1726"]},"citation":{"ieee":"E. J. Agnes and T. P. Vogels, “Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks,” <i>Nature Neuroscience</i>, vol. 27. Springer Nature, pp. 964–974, 2024.","chicago":"Agnes, Everton J., and Tim P Vogels. “Co-Dependent Excitatory and Inhibitory Plasticity Accounts for Quick, Stable and Long-Lasting Memories in Biological Networks.” <i>Nature Neuroscience</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41593-024-01597-4\">https://doi.org/10.1038/s41593-024-01597-4</a>.","mla":"Agnes, Everton J., and Tim P. Vogels. “Co-Dependent Excitatory and Inhibitory Plasticity Accounts for Quick, Stable and Long-Lasting Memories in Biological Networks.” <i>Nature Neuroscience</i>, vol. 27, Springer Nature, 2024, pp. 964–74, doi:<a href=\"https://doi.org/10.1038/s41593-024-01597-4\">10.1038/s41593-024-01597-4</a>.","apa":"Agnes, E. J., &#38; Vogels, T. P. (2024). Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. <i>Nature Neuroscience</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41593-024-01597-4\">https://doi.org/10.1038/s41593-024-01597-4</a>","ama":"Agnes EJ, Vogels TP. Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. <i>Nature Neuroscience</i>. 2024;27:964-974. doi:<a href=\"https://doi.org/10.1038/s41593-024-01597-4\">10.1038/s41593-024-01597-4</a>","ista":"Agnes EJ, Vogels TP. 2024. Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks. Nature Neuroscience. 27, 964–974.","short":"E.J. Agnes, T.P. Vogels, Nature Neuroscience 27 (2024) 964–974."},"intvolume":"        27","external_id":{"pmid":["38509348 "],"isi":["001190081400001"]},"OA_type":"hybrid","article_type":"original","file":[{"file_name":"2025_NatureNeuroscience_Agnes.pdf","file_size":10508018,"date_updated":"2025-06-25T08:45:32Z","access_level":"open_access","relation":"main_file","success":1,"creator":"dernst","file_id":"19902","checksum":"dfca68a24749575b912b3a78a7de4516","content_type":"application/pdf","date_created":"2025-06-25T08:45:32Z"}],"page":"964-974","author":[{"first_name":"Everton J.","last_name":"Agnes","full_name":"Agnes, Everton J."},{"id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","full_name":"Vogels, Tim P","orcid":"0000-0003-3295-6181","first_name":"Tim P","last_name":"Vogels"}],"day":"01","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_updated":"2025-09-04T13:06:06Z","fulldoi":"https://doi.org/10.1038/s41593-024-01597-4","file_date_updated":"2025-06-25T08:45:32Z","month":"05","title":"Co-dependent excitatory and inhibitory plasticity accounts for quick, stable and long-lasting memories in biological networks","has_accepted_license":"1","date_created":"2024-03-24T23:01:00Z","publication":"Nature Neuroscience","OA_place":"publisher"},{"isi":1,"project":[{"_id":"059876FA-7A3F-11EA-A408-12923DDC885E","name":"Prix Lopez-Loretta 2019 - Marco Mondelli"}],"article_processing_charge":"No","oa":1,"department":[{"_id":"MaMo"}],"scopus_import":"1","language":[{"iso":"eng"}],"oa_version":"Preprint","corr_author":"1","abstract":[{"lang":"eng","text":"We propose a novel approach to concentration for non-independent random variables. The main idea is to “pretend” that the random variables are independent and pay a multiplicative price measuring how far they are from actually being independent. This price is encapsulated in the Hellinger integral between the joint and the product of the marginals, which is then upper bounded leveraging tensorisation properties. Our bounds represent a natural generalisation of concentration inequalities in the presence of dependence: we recover exactly the classical bounds (McDiarmid’s inequality) when the random variables are independent. Furthermore, in a “large deviations” regime, we obtain the same decay in the probability as for the independent case, even when the random variables display non-trivial dependencies. To show this, we consider a number of applications of interest. First, we provide a bound for Markov chains with finite state space. Then, we consider the Simple Symmetric Random Walk, which is a non-contracting Markov chain, and a non-Markovian setting in which the stochastic process depends on its entire past. To conclude, we propose an application to Markov Chain Monte Carlo methods, where our approach leads to an improved lower bound on the minimum burn-in period required to reach a certain accuracy. In all of these settings, we provide a regime of parameters in which our bound fares better than what the state of the art can provide."}],"publication_status":"published","publisher":"IEEE","publication_identifier":{"issn":["0018-9448"],"eissn":["1557-9654"]},"citation":{"ieee":"A. R. Esposito and M. Mondelli, “Concentration without independence via information measures,” <i>IEEE Transactions on Information Theory</i>, vol. 70, no. 6. IEEE, pp. 3823–3839, 2024.","mla":"Esposito, Amedeo Roberto, and Marco Mondelli. “Concentration without Independence via Information Measures.” <i>IEEE Transactions on Information Theory</i>, vol. 70, no. 6, IEEE, 2024, pp. 3823–39, doi:<a href=\"https://doi.org/10.1109/TIT.2024.3367767\">10.1109/TIT.2024.3367767</a>.","chicago":"Esposito, Amedeo Roberto, and Marco Mondelli. “Concentration without Independence via Information Measures.” <i>IEEE Transactions on Information Theory</i>. IEEE, 2024. <a href=\"https://doi.org/10.1109/TIT.2024.3367767\">https://doi.org/10.1109/TIT.2024.3367767</a>.","ama":"Esposito AR, Mondelli M. Concentration without independence via information measures. <i>IEEE Transactions on Information Theory</i>. 2024;70(6):3823-3839. doi:<a href=\"https://doi.org/10.1109/TIT.2024.3367767\">10.1109/TIT.2024.3367767</a>","apa":"Esposito, A. R., &#38; Mondelli, M. (2024). Concentration without independence via information measures. <i>IEEE Transactions on Information Theory</i>. IEEE. <a href=\"https://doi.org/10.1109/TIT.2024.3367767\">https://doi.org/10.1109/TIT.2024.3367767</a>","short":"A.R. Esposito, M. Mondelli, IEEE Transactions on Information Theory 70 (2024) 3823–3839.","ista":"Esposito AR, Mondelli M. 2024. Concentration without independence via information measures. IEEE Transactions on Information Theory. 70(6), 3823–3839."},"intvolume":"        70","_id":"15172","date_published":"2024-06-01T00:00:00Z","status":"public","year":"2024","quality_controlled":"1","volume":70,"doi":"10.1109/TIT.2024.3367767","page":"3823-3839","day":"01","author":[{"last_name":"Esposito","first_name":"Amedeo Roberto","id":"9583e921-e1ad-11ec-9862-cef099626dc9","full_name":"Esposito, Amedeo Roberto"},{"first_name":"Marco","last_name":"Mondelli","id":"27EB676C-8706-11E9-9510-7717E6697425","orcid":"0000-0002-3242-7020","full_name":"Mondelli, Marco"}],"arxiv":1,"type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","related_material":{"record":[{"status":"public","id":"14922","relation":"earlier_version"}]},"external_id":{"arxiv":["2303.07245"],"isi":["001230181100001"]},"article_type":"original","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2303.07245"}],"title":"Concentration without independence via information measures","date_created":"2024-03-24T23:01:00Z","publication":"IEEE Transactions on Information Theory","fulldoi":"https://doi.org/10.1109/TIT.2024.3367767","date_updated":"2025-09-04T13:06:53Z","month":"06","issue":"6"},{"acknowledgement":"We thank Milaboratory (milaboratory.com) for the access to computing and storage infrastructure. We thank J. Petrasek for providing the BY-2 cell culture line. We thank Konstantin Lukyanov laboratory and Sergey Deyev laboratory for assistance with experiments.\r\nThis study was partially funded by Light Bio and Planta. The Synthetic biology Group is funded by the MRC London Institute of Medical Sciences (UKRI MC-A658-5QEA0). Cloning and luminescent assays performed in BY-2 were partially supported by RSF, project number 22-14-00400, https://rscf.ru/project/22-14-00400/. Plant transformations were funded by RFBR and MOST, project number 21-54-52004. Plant imaging experiments were funded by RSF, project number 22-74-00124, https://rscf.ru/project/22-74-00124/. Viral delivery experiments were funded by the grant PID2019-108203RB-I00 Plan Nacional I + D from the Ministerio de Ciencia e Innovación (Spain) through the Agencia Estatal de Investigación (cofinanced by the European Regional Development Fund).","doi":"10.1126/sciadv.adk1992","quality_controlled":"1","volume":10,"year":"2024","status":"public","date_published":"2024-03-01T00:00:00Z","_id":"15179","intvolume":"        10","citation":{"chicago":"Palkina, Kseniia A., Tatiana A. Karataeva, Maxim M. Perfilov, Liliia I. Fakhranurova, Nadezhda M. Markina, Louisa Gonzalez Somermeyer, Elena Garcia-Perez, et al. “A Hybrid Pathway for Self-Sustained Luminescence.” <i>Science Advances</i>. American Association for the Advancement of Science, 2024. <a href=\"https://doi.org/10.1126/sciadv.adk1992\">https://doi.org/10.1126/sciadv.adk1992</a>.","ieee":"K. A. Palkina <i>et al.</i>, “A hybrid pathway for self-sustained luminescence,” <i>Science Advances</i>, vol. 10, no. 10. American Association for the Advancement of Science, 2024.","mla":"Palkina, Kseniia A., et al. “A Hybrid Pathway for Self-Sustained Luminescence.” <i>Science Advances</i>, vol. 10, no. 10, adk1992, American Association for the Advancement of Science, 2024, doi:<a href=\"https://doi.org/10.1126/sciadv.adk1992\">10.1126/sciadv.adk1992</a>.","apa":"Palkina, K. A., Karataeva, T. A., Perfilov, M. M., Fakhranurova, L. I., Markina, N. M., Gonzalez Somermeyer, L., … Sarkisyan, K. S. (2024). A hybrid pathway for self-sustained luminescence. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.adk1992\">https://doi.org/10.1126/sciadv.adk1992</a>","ama":"Palkina KA, Karataeva TA, Perfilov MM, et al. A hybrid pathway for self-sustained luminescence. <i>Science Advances</i>. 2024;10(10). doi:<a href=\"https://doi.org/10.1126/sciadv.adk1992\">10.1126/sciadv.adk1992</a>","short":"K.A. Palkina, T.A. Karataeva, M.M. Perfilov, L.I. Fakhranurova, N.M. Markina, L. Gonzalez Somermeyer, E. Garcia-Perez, M. Vazquez-Vilar, M. Rodriguez-Rodriguez, V. Vazquez-Vilriales, E.S. Shakhova, T. Mitiouchkina, O.A. Belozerova, S.I. Kovalchuk, A. Alekberova, A.K. Malyshevskaia, E.N. Bugaeva, E.B. Guglya, A. Balakireva, N. Sytov, A. Bezlikhotnova, D.I. Boldyreva, V.V. Babenko, F. Kondrashov, V.V. Choob, D. Orzaez, I.V. Yampolsky, A.S. Mishin, K.S. Sarkisyan, Science Advances 10 (2024).","ista":"Palkina KA, Karataeva TA, Perfilov MM, Fakhranurova LI, Markina NM, Gonzalez Somermeyer L, Garcia-Perez E, Vazquez-Vilar M, Rodriguez-Rodriguez M, Vazquez-Vilriales V, Shakhova ES, Mitiouchkina T, Belozerova OA, Kovalchuk SI, Alekberova A, Malyshevskaia AK, Bugaeva EN, Guglya EB, Balakireva A, Sytov N, Bezlikhotnova A, Boldyreva DI, Babenko VV, Kondrashov F, Choob VV, Orzaez D, Yampolsky IV, Mishin AS, Sarkisyan KS. 2024. A hybrid pathway for self-sustained luminescence. Science Advances. 10(10), adk1992."},"publication_identifier":{"eissn":["2375-2548"]},"publication_status":"published","DOAJ_listed":"1","publisher":"American Association for the Advancement of Science","abstract":[{"lang":"eng","text":"The fungal bioluminescence pathway can be reconstituted in other organisms allowing luminescence imaging without exogenously supplied substrate. The pathway starts from hispidin biosynthesis—a step catalyzed by a large fungal polyketide synthase that requires a posttranslational modification for activity. Here, we report identification of alternative compact hispidin synthases encoded by a phylogenetically diverse group of plants. A hybrid bioluminescence pathway that combines plant and fungal genes is more compact, not dependent on availability of machinery for posttranslational modifications, and confers autonomous bioluminescence in yeast, mammalian, and plant hosts. The compact size of plant hispidin synthases enables additional modes of delivery of autoluminescence, such as delivery with viral vectors."}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"pmid":1,"language":[{"iso":"eng"}],"scopus_import":"1","department":[{"_id":"FyKo"}],"oa":1,"article_number":"adk1992","article_processing_charge":"Yes","isi":1,"ddc":["580"],"issue":"10","month":"03","file_date_updated":"2024-03-25T09:42:10Z","fulldoi":"https://doi.org/10.1126/sciadv.adk1992","date_updated":"2025-09-04T13:16:05Z","OA_place":"publisher","date_created":"2024-03-25T08:54:33Z","publication":"Science Advances","has_accepted_license":"1","title":"A hybrid pathway for self-sustained luminescence","file":[{"checksum":"a19c43b260ea0bbaf895a29712e3153c","content_type":"application/pdf","file_id":"15185","date_created":"2024-03-25T09:42:10Z","file_size":1499302,"file_name":"2024_ScienceAdv_Palkina.pdf","date_updated":"2024-03-25T09:42:10Z","creator":"dernst","success":1,"relation":"main_file","access_level":"open_access"}],"article_type":"original","OA_type":"gold","external_id":{"isi":["001187580500013"],"pmid":["38457503"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","author":[{"last_name":"Palkina","first_name":"Kseniia A.","full_name":"Palkina, Kseniia A."},{"full_name":"Karataeva, Tatiana A.","last_name":"Karataeva","first_name":"Tatiana A."},{"full_name":"Perfilov, Maxim M.","last_name":"Perfilov","first_name":"Maxim M."},{"last_name":"Fakhranurova","first_name":"Liliia I.","full_name":"Fakhranurova, Liliia I."},{"full_name":"Markina, Nadezhda M.","last_name":"Markina","first_name":"Nadezhda M."},{"orcid":"0000-0001-9139-5383","full_name":"Gonzalez Somermeyer, Louisa","id":"4720D23C-F248-11E8-B48F-1D18A9856A87","first_name":"Louisa","last_name":"Gonzalez Somermeyer"},{"full_name":"Garcia-Perez, Elena","last_name":"Garcia-Perez","first_name":"Elena"},{"last_name":"Vazquez-Vilar","first_name":"Marta","full_name":"Vazquez-Vilar, Marta"},{"full_name":"Rodriguez-Rodriguez, Marta","first_name":"Marta","last_name":"Rodriguez-Rodriguez"},{"full_name":"Vazquez-Vilriales, Victor","last_name":"Vazquez-Vilriales","first_name":"Victor"},{"full_name":"Shakhova, Ekaterina S.","first_name":"Ekaterina S.","last_name":"Shakhova"},{"last_name":"Mitiouchkina","first_name":"Tatiana","full_name":"Mitiouchkina, Tatiana"},{"full_name":"Belozerova, Olga A.","first_name":"Olga A.","last_name":"Belozerova"},{"full_name":"Kovalchuk, Sergey I.","last_name":"Kovalchuk","first_name":"Sergey I."},{"first_name":"Anna","last_name":"Alekberova","full_name":"Alekberova, Anna"},{"full_name":"Malyshevskaia, Alena K.","first_name":"Alena K.","last_name":"Malyshevskaia"},{"full_name":"Bugaeva, Evgenia N.","first_name":"Evgenia N.","last_name":"Bugaeva"},{"last_name":"Guglya","first_name":"Elena B.","full_name":"Guglya, Elena B."},{"full_name":"Balakireva, Anastasia","first_name":"Anastasia","last_name":"Balakireva"},{"full_name":"Sytov, Nikita","last_name":"Sytov","first_name":"Nikita"},{"full_name":"Bezlikhotnova, Anastasia","last_name":"Bezlikhotnova","first_name":"Anastasia"},{"full_name":"Boldyreva, Daria I.","first_name":"Daria I.","last_name":"Boldyreva"},{"full_name":"Babenko, Vladislav V.","first_name":"Vladislav V.","last_name":"Babenko"},{"first_name":"Fyodor","last_name":"Kondrashov","full_name":"Kondrashov, Fyodor","orcid":"0000-0001-8243-4694","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Choob, Vladimir V.","last_name":"Choob","first_name":"Vladimir V."},{"last_name":"Orzaez","first_name":"Diego","full_name":"Orzaez, Diego"},{"full_name":"Yampolsky, Ilia V.","last_name":"Yampolsky","first_name":"Ilia V."},{"last_name":"Mishin","first_name":"Alexander S.","full_name":"Mishin, Alexander S."},{"full_name":"Sarkisyan, Karen S.","first_name":"Karen S.","last_name":"Sarkisyan"}],"day":"01"},{"ddc":["530"],"article_processing_charge":"Yes","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"scopus_import":"1","department":[{"_id":"MiLe"}],"oa":1,"article_number":"013257","language":[{"iso":"eng"}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"abstract":[{"lang":"eng","text":"We demonstrate the failure of the adiabatic Born-Oppenheimer approximation to describe the ground state of a quantum impurity within an ultracold Fermi gas despite substantial mass differences between the bath and impurity species. Increasing repulsion leads to the appearance of nonadiabatic couplings between the fast bath and slow impurity degrees of freedom, which reduce the parity symmetry of the latter according to the pseudo Jahn-Teller effect. The presence of this mechanism is associated to a conical intersection involving the impurity position and the inverse of the interaction strength, which acts as a synthetic dimension. We elucidate the presence of these effects via a detailed ground-state analysis involving the comparison of ab initio fully correlated simulations with effective models. Our study suggests ultracold atomic ensembles as potent emulators of complex molecular phenomena."}],"publication_identifier":{"eissn":["2643-1564"]},"publisher":"American Physical Society","ec_funded":1,"DOAJ_listed":"1","publication_status":"published","intvolume":"         6","citation":{"short":"A. Becker, G. Koutentakis, P. Schmelcher, Physical Review Research 6 (2024).","ista":"Becker A, Koutentakis G, Schmelcher P. 2024. Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. Physical Review Research. 6(1), 013257.","ama":"Becker A, Koutentakis G, Schmelcher P. Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. <i>Physical Review Research</i>. 2024;6(1). doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">10.1103/physrevresearch.6.013257</a>","apa":"Becker, A., Koutentakis, G., &#38; Schmelcher, P. (2024). Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">https://doi.org/10.1103/physrevresearch.6.013257</a>","chicago":"Becker, A., Georgios Koutentakis, and P. Schmelcher. “Synthetic Dimension-Induced Pseudo Jahn-Teller Effect in One-Dimensional Confined Fermions.” <i>Physical Review Research</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">https://doi.org/10.1103/physrevresearch.6.013257</a>.","mla":"Becker, A., et al. “Synthetic Dimension-Induced Pseudo Jahn-Teller Effect in One-Dimensional Confined Fermions.” <i>Physical Review Research</i>, vol. 6, no. 1, 013257, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013257\">10.1103/physrevresearch.6.013257</a>.","ieee":"A. Becker, G. Koutentakis, and P. Schmelcher, “Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions,” <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024."},"date_published":"2024-03-01T00:00:00Z","_id":"15181","year":"2024","status":"public","volume":6,"quality_controlled":"1","acknowledgement":"This work has been funded by the Cluster of Excellence “Advanced Imaging of Matter” of the Deutsche Forschungsgemeinschaft (DFG) - EXC 2056 - Project ID 390715994.\r\nG.M.K. gratefully acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.","doi":"10.1103/physrevresearch.6.013257","day":"01","author":[{"last_name":"Becker","first_name":"A.","full_name":"Becker, A."},{"full_name":"Koutentakis, Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95","first_name":"Georgios","last_name":"Koutentakis"},{"full_name":"Schmelcher, P.","last_name":"Schmelcher","first_name":"P."}],"arxiv":1,"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"arxiv":["2310.17995"]},"article_type":"original","file":[{"file_size":2207067,"date_updated":"2024-03-25T09:24:55Z","file_name":"2024_PhysicalReviewResearch_Becker.pdf","access_level":"open_access","relation":"main_file","creator":"dernst","success":1,"file_id":"15183","content_type":"application/pdf","checksum":"4e0e58d1f58386fb016284c84db2a300","date_created":"2024-03-25T09:24:55Z"}],"has_accepted_license":"1","title":"Synthetic dimension-induced pseudo Jahn-Teller effect in one-dimensional confined fermions","date_created":"2024-03-25T08:57:07Z","publication":"Physical Review Research","fulldoi":"https://doi.org/10.1103/physrevresearch.6.013257","date_updated":"2025-05-14T09:32:03Z","file_date_updated":"2024-03-25T09:24:55Z","issue":"1","month":"03"},{"quality_controlled":"1","volume":51,"acknowledgement":"YLH is supported by funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant 101034413. CM gratefully acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant 805041). The authors warmly thank Steven Sherwood, Jiawei Bao, Bidyut Goswami, and Martin Janssens for stimulating and helpful discussions. They also thank Christopher Holloway and an anonymous reviewer for providing helpful feedback that greatly improved this manuscript.\r\n","APC_amount":"2940 EUR","doi":"10.1029/2023gl106523","date_published":"2024-03-19T00:00:00Z","_id":"15186","year":"2024","status":"public","publication_identifier":{"eissn":["1944-8007"],"issn":["0094-8276"]},"ec_funded":1,"DOAJ_listed":"1","publisher":"Wiley","publication_status":"published","intvolume":"        51","citation":{"ama":"Hwong Y-L, Muller CJ. The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. <i>Geophysical Research Letters</i>. 2024;51(6). doi:<a href=\"https://doi.org/10.1029/2023gl106523\">10.1029/2023gl106523</a>","apa":"Hwong, Y.-L., &#38; Muller, C. J. (2024). The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2023gl106523\">https://doi.org/10.1029/2023gl106523</a>","mla":"Hwong, Yi-Ling, and Caroline J. Muller. “The Unreasonable Efficiency of Total Rain Evaporation Removal in Triggering Convective Self‐aggregation.” <i>Geophysical Research Letters</i>, vol. 51, no. 6, e2023GL106523, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023gl106523\">10.1029/2023gl106523</a>.","chicago":"Hwong, Yi-Ling, and Caroline J Muller. “The Unreasonable Efficiency of Total Rain Evaporation Removal in Triggering Convective Self‐aggregation.” <i>Geophysical Research Letters</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023gl106523\">https://doi.org/10.1029/2023gl106523</a>.","ieee":"Y.-L. Hwong and C. J. Muller, “The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation,” <i>Geophysical Research Letters</i>, vol. 51, no. 6. Wiley, 2024.","short":"Y.-L. Hwong, C.J. Muller, Geophysical Research Letters 51 (2024).","ista":"Hwong Y-L, Muller CJ. 2024. The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation. Geophysical Research Letters. 51(6), e2023GL106523."},"oa_version":"Published Version","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"corr_author":"1","abstract":[{"lang":"eng","text":"The elimination of rain evaporation in the planetary boundary layer (PBL) has been found to lead to convective self‐aggregation (CSA) even without radiative feedback, but the precise mechanisms underlying this phenomenon remain unclear. We conducted cloud‐resolving simulations with two domain sizes and progressively reduced rain evaporation in the PBL. Surprisingly, CSA only occurred when rain evaporation was almost completely removed. The additional convective heating resulting from the reduction of evaporative cooling in the moist patch was found to be the trigger, thereafter a dry subsidence intrusion into the PBL in the dry patch takes over and sets CSA in motion. Temperature and moisture anomalies oppose each other in their buoyancy effects, hence explaining the need for almost total rain evaporation removal. We also found radiative cooling and not cold pools to be the leading cause for the comparative ease of CSA to take place in the larger domain."}],"language":[{"iso":"eng"}],"article_processing_charge":"Yes","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"_id":"629205d8-2b32-11ec-9570-e1356ff73576","grant_number":"805041","call_identifier":"H2020","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate"}],"scopus_import":"1","department":[{"_id":"CaMu"}],"oa":1,"article_number":" e2023GL106523","isi":1,"ddc":["550"],"issue":"6","month":"03","fulldoi":"https://doi.org/10.1029/2023gl106523","date_updated":"2025-09-04T13:16:39Z","file_date_updated":"2024-03-25T11:28:25Z","publication":"Geophysical Research Letters","date_created":"2024-03-25T10:27:30Z","OA_place":"publisher","has_accepted_license":"1","title":"The unreasonable efficiency of total rain evaporation removal in triggering convective self‐aggregation","keyword":["General Earth and Planetary Sciences","Geophysics"],"file":[{"file_id":"15187","content_type":"application/pdf","checksum":"eacb011091a503b9e7b748fef639ba4c","date_created":"2024-03-25T11:28:25Z","file_size":1280108,"date_updated":"2024-03-25T11:28:25Z","file_name":"2024_GeophysResLetters_Hwong.pdf","relation":"main_file","access_level":"open_access","success":1,"creator":"dernst"}],"article_type":"original","external_id":{"isi":["001187002300001"]},"OA_type":"gold","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","related_material":{"record":[{"status":"public","id":"19307","relation":"research_data"}]},"day":"19","author":[{"first_name":"Yi-Ling","last_name":"Hwong","id":"1217aa61-4dd1-11ec-9ac3-f2ba3f17ee22","full_name":"Hwong, Yi-Ling","orcid":"0000-0001-9281-3479"},{"orcid":"0000-0001-5836-5350","full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","first_name":"Caroline J","last_name":"Muller"}]},{"quality_controlled":"1","volume":528,"doi":"10.1093/mnras/stae012","_id":"15189","date_published":"2024-01-04T00:00:00Z","status":"public","year":"2024","publication_status":"published","publisher":"Oxford University Press","publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"citation":{"apa":"Galiullin, I., Rodriguez, A. C., Kulkarni, S. R., Sunyaev, R., Gilfanov, M., Bikmaev, I., … Vanderbosch, Z. P. (2024). A joint SRG/eROSITA + ZTF search: Discovery of a 97-min period eclipsing cataclysmic variable with evidence of a brown dwarf secondary. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stae012\">https://doi.org/10.1093/mnras/stae012</a>","ama":"Galiullin I, Rodriguez AC, Kulkarni SR, et al. A joint SRG/eROSITA + ZTF search: Discovery of a 97-min period eclipsing cataclysmic variable with evidence of a brown dwarf secondary. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;528(1):676-692. doi:<a href=\"https://doi.org/10.1093/mnras/stae012\">10.1093/mnras/stae012</a>","chicago":"Galiullin, Ilkham, Antonio C Rodriguez, Shrinivas R Kulkarni, Rashid Sunyaev, Marat Gilfanov, Ilfan Bikmaev, Lev Yungelson, et al. “A Joint SRG/EROSITA + ZTF Search: Discovery of a 97-Min Period Eclipsing Cataclysmic Variable with Evidence of a Brown Dwarf Secondary.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stae012\">https://doi.org/10.1093/mnras/stae012</a>.","mla":"Galiullin, Ilkham, et al. “A Joint SRG/EROSITA + ZTF Search: Discovery of a 97-Min Period Eclipsing Cataclysmic Variable with Evidence of a Brown Dwarf Secondary.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 528, no. 1, Oxford University Press, 2024, pp. 676–92, doi:<a href=\"https://doi.org/10.1093/mnras/stae012\">10.1093/mnras/stae012</a>.","ieee":"I. Galiullin <i>et al.</i>, “A joint SRG/eROSITA + ZTF search: Discovery of a 97-min period eclipsing cataclysmic variable with evidence of a brown dwarf secondary,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 528, no. 1. Oxford University Press, pp. 676–692, 2024.","ista":"Galiullin I, Rodriguez AC, Kulkarni SR, Sunyaev R, Gilfanov M, Bikmaev I, Yungelson L, van Roestel J, Gänsicke BT, Khamitov I, Szkody P, El-Badry K, Suslikov M, Prince TA, Buntov M, Caiazzo I, Gorbachev M, Graham MJ, Gumerov R, Irtuganov E, Laher RR, Medvedev P, Riddle R, Rusholme B, Sakhibullin N, Sklyanov A, Vanderbosch ZP. 2024. A joint SRG/eROSITA + ZTF search: Discovery of a 97-min period eclipsing cataclysmic variable with evidence of a brown dwarf secondary. Monthly Notices of the Royal Astronomical Society. 528(1), 676–692.","short":"I. Galiullin, A.C. Rodriguez, S.R. Kulkarni, R. Sunyaev, M. Gilfanov, I. Bikmaev, L. Yungelson, J. van Roestel, B.T. Gänsicke, I. Khamitov, P. Szkody, K. El-Badry, M. Suslikov, T.A. Prince, M. Buntov, I. Caiazzo, M. Gorbachev, M.J. Graham, R. Gumerov, E. Irtuganov, R.R. Laher, P. Medvedev, R. Riddle, B. Rusholme, N. Sakhibullin, A. Sklyanov, Z.P. Vanderbosch, Monthly Notices of the Royal Astronomical Society 528 (2024) 676–692."},"intvolume":"       528","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","abstract":[{"lang":"eng","text":"Cataclysmic variables (CVs) that have evolved past the period minimum during their lifetimes are predicted to be systems with a brown dwarf donor. While population synthesis models predict that around 40–70 per cent of the Galactic CVs are post-period minimum systems referred to as ‘period bouncers’, only a few dozen confirmed systems are known. We report the study and characterization of a new eclipsing CV, SRGeJ041130.3+685350 (SRGeJ0411), discovered from a joint SRG/eROSITA and ZTF programme. The optical spectrum of SRGeJ0411 shows prominent hydrogen and helium emission lines, typical for CVs. We obtained optical high-speed photometry to confirm the eclipse of SRGeJ0411 and determine the orbital period to be Porb ≈ 97.530 min. The spectral energy distribution suggests that the donor has an effective temperature of ≲ 1800 K. We constrain the donor mass with the period–density relationship for Roche lobe-filling stars and find that Mdonor ≲ 0.04 M⊙. The binary parameters are consistent with evolutionary models for post-period minimum CVs, suggesting that SRGeJ0411 is a new period bouncer. The optical emission lines of SRGeJ0411 are single-peaked despite the system being eclipsing, which is typically only seen due to stream-fed accretion in polars. X-ray spectroscopy hints that the white dwarf in SRGeJ0411 could be magnetic, but verifying the magnetic nature of SRGeJ0411 requires further investigation. The lack of optical outbursts has made SRGeJ0411 elusive in previous surveys, and joint X-ray and optical surveys highlight the potential for discovering similar systems in the near future."}],"language":[{"iso":"eng"}],"article_processing_charge":"No","oa":1,"scopus_import":"1","month":"01","issue":"1","fulldoi":"https://doi.org/10.1093/mnras/stae012","date_updated":"2024-04-02T06:50:01Z","extern":"1","publication":"Monthly Notices of the Royal Astronomical Society","date_created":"2024-03-26T09:43:55Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/mnras/stae012"}],"title":"A joint SRG/eROSITA + ZTF search: Discovery of a 97-min period eclipsing cataclysmic variable with evidence of a brown dwarf secondary","article_type":"original","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"external_id":{"arxiv":["2401.04178"]},"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"676-692","day":"04","author":[{"first_name":"Ilkham","last_name":"Galiullin","full_name":"Galiullin, Ilkham"},{"last_name":"Rodriguez","first_name":"Antonio C","full_name":"Rodriguez, Antonio C"},{"first_name":"Shrinivas R","last_name":"Kulkarni","full_name":"Kulkarni, Shrinivas R"},{"last_name":"Sunyaev","first_name":"Rashid","full_name":"Sunyaev, Rashid"},{"full_name":"Gilfanov, Marat","first_name":"Marat","last_name":"Gilfanov"},{"full_name":"Bikmaev, Ilfan","last_name":"Bikmaev","first_name":"Ilfan"},{"full_name":"Yungelson, Lev","first_name":"Lev","last_name":"Yungelson"},{"last_name":"van Roestel","first_name":"Jan","full_name":"van Roestel, Jan"},{"full_name":"Gänsicke, Boris T","last_name":"Gänsicke","first_name":"Boris T"},{"first_name":"Irek","last_name":"Khamitov","full_name":"Khamitov, Irek"},{"full_name":"Szkody, Paula","last_name":"Szkody","first_name":"Paula"},{"full_name":"El-Badry, Kareem","last_name":"El-Badry","first_name":"Kareem"},{"last_name":"Suslikov","first_name":"Mikhail","full_name":"Suslikov, Mikhail"},{"last_name":"Prince","first_name":"Thomas A","full_name":"Prince, Thomas A"},{"full_name":"Buntov, Mikhail","last_name":"Buntov","first_name":"Mikhail"},{"first_name":"Ilaria","last_name":"Caiazzo","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","full_name":"Caiazzo, Ilaria"},{"full_name":"Gorbachev, Mark","last_name":"Gorbachev","first_name":"Mark"},{"full_name":"Graham, Matthew J","last_name":"Graham","first_name":"Matthew J"},{"full_name":"Gumerov, Rustam","last_name":"Gumerov","first_name":"Rustam"},{"last_name":"Irtuganov","first_name":"Eldar","full_name":"Irtuganov, Eldar"},{"first_name":"Russ R","last_name":"Laher","full_name":"Laher, Russ R"},{"last_name":"Medvedev","first_name":"Pavel","full_name":"Medvedev, Pavel"},{"full_name":"Riddle, Reed","last_name":"Riddle","first_name":"Reed"},{"full_name":"Rusholme, Ben","first_name":"Ben","last_name":"Rusholme"},{"last_name":"Sakhibullin","first_name":"Nail","full_name":"Sakhibullin, Nail"},{"last_name":"Sklyanov","first_name":"Alexander","full_name":"Sklyanov, Alexander"},{"first_name":"Zachary P","last_name":"Vanderbosch","full_name":"Vanderbosch, Zachary P"}],"arxiv":1},{"publication":"The Astrophysical Journal","date_created":"2024-03-26T09:44:50Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.3847/1538-4357/ad08bf"}],"title":"Exploring the chemistry and mass function of the globular cluster 47 Tucanae with new theoretical color–magnitude diagrams","issue":"1","month":"01","extern":"1","fulldoi":"https://doi.org/10.3847/1538-4357/ad08bf","date_updated":"2024-04-02T06:52:43Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","arxiv":1,"day":"22","author":[{"last_name":"Gerasimov","first_name":"Roman","full_name":"Gerasimov, Roman"},{"first_name":"Adam J.","last_name":"Burgasser","full_name":"Burgasser, Adam J."},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","full_name":"Caiazzo, Ilaria","last_name":"Caiazzo","first_name":"Ilaria"},{"full_name":"Homeier, Derek","first_name":"Derek","last_name":"Homeier"},{"first_name":"Harvey B.","last_name":"Richer","full_name":"Richer, Harvey B."},{"full_name":"Correnti, Matteo","first_name":"Matteo","last_name":"Correnti"},{"first_name":"Jeremy","last_name":"Heyl","full_name":"Heyl, Jeremy"}],"keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"article_type":"original","external_id":{"arxiv":["2310.11800"]},"intvolume":"       961","citation":{"short":"R. Gerasimov, A.J. Burgasser, I. Caiazzo, D. Homeier, H.B. Richer, M. Correnti, J. Heyl, The Astrophysical Journal 961 (2024).","ista":"Gerasimov R, Burgasser AJ, Caiazzo I, Homeier D, Richer HB, Correnti M, Heyl J. 2024. Exploring the chemistry and mass function of the globular cluster 47 Tucanae with new theoretical color–magnitude diagrams. The Astrophysical Journal. 961(1), 139.","ieee":"R. Gerasimov <i>et al.</i>, “Exploring the chemistry and mass function of the globular cluster 47 Tucanae with new theoretical color–magnitude diagrams,” <i>The Astrophysical Journal</i>, vol. 961, no. 1. American Astronomical Society, 2024.","chicago":"Gerasimov, Roman, Adam J. Burgasser, Ilaria Caiazzo, Derek Homeier, Harvey B. Richer, Matteo Correnti, and Jeremy Heyl. “Exploring the Chemistry and Mass Function of the Globular Cluster 47 Tucanae with New Theoretical Color–Magnitude Diagrams.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad08bf\">https://doi.org/10.3847/1538-4357/ad08bf</a>.","mla":"Gerasimov, Roman, et al. “Exploring the Chemistry and Mass Function of the Globular Cluster 47 Tucanae with New Theoretical Color–Magnitude Diagrams.” <i>The Astrophysical Journal</i>, vol. 961, no. 1, 139, American Astronomical Society, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad08bf\">10.3847/1538-4357/ad08bf</a>.","apa":"Gerasimov, R., Burgasser, A. J., Caiazzo, I., Homeier, D., Richer, H. B., Correnti, M., &#38; Heyl, J. (2024). Exploring the chemistry and mass function of the globular cluster 47 Tucanae with new theoretical color–magnitude diagrams. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/ad08bf\">https://doi.org/10.3847/1538-4357/ad08bf</a>","ama":"Gerasimov R, Burgasser AJ, Caiazzo I, et al. Exploring the chemistry and mass function of the globular cluster 47 Tucanae with new theoretical color–magnitude diagrams. <i>The Astrophysical Journal</i>. 2024;961(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ad08bf\">10.3847/1538-4357/ad08bf</a>"},"publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"publication_status":"published","publisher":"American Astronomical Society","abstract":[{"lang":"eng","text":"Despite their shared origin, members of globular clusters display star-to-star variations in composition. The observed pattern of element abundances is unique to these stellar environments and cannot be fully explained by any proposed mechanism. It remains unclear whether stars form with chemical heterogeneity or inherit it from interactions with other members. These scenarios may be differentiated by the dependence of chemical spread on stellar mass; however, obtaining a sufficiently large mass baseline requires abundance measurements on the lower main sequence, which is too faint for spectroscopy even in the nearest globular clusters. We developed a stellar modeling method to obtain precise chemical abundances for stars near the end of the main sequence from multiband photometry, and we applied it to the globular cluster 47 Tucanae. The computational efficiency is attained by matching chemical elements to the model components that are most sensitive to their abundance. We determined [O/Fe] for ∼5000 members below the main-sequence knee at the level of accuracy, comparable to the spectroscopic measurements of evolved members in the literature. The inferred distribution disfavors stellar interactions as the origin of chemical spread; however, an accurate theory of accretion is required to draw a more definitive conclusion. We anticipate that future observations of 47 Tucanae with the James Webb Space Telescope will extend the mass baseline of our analysis into the substellar regime. Therefore, we present predicted color–magnitude diagrams and mass–magnitude relations for the brown dwarf members of 47 Tucanae."}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"doi":"10.3847/1538-4357/ad08bf","volume":961,"quality_controlled":"1","year":"2024","status":"public","date_published":"2024-01-22T00:00:00Z","_id":"15191","language":[{"iso":"eng"}],"scopus_import":"1","oa":1,"article_number":"139","article_processing_charge":"No"},{"volume":206,"quality_controlled":"1","doi":"10.1016/j.jcta.2024.105889","acknowledgement":"We are grateful to Balázs Keszegh, and to the members of the Miklós Schweitzer Competition committee of 2022 for valuable discussions, and Shira Zerbib for pointing out several important mathematical typos.","_id":"15247","date_published":"2024-08-01T00:00:00Z","status":"public","year":"2024","publisher":"Elsevier","publication_status":"published","publication_identifier":{"issn":["0097-3165"],"eissn":["1096-0899"]},"citation":{"short":"P. Frankl, J. Pach, D. Pálvölgyi, Journal of Combinatorial Theory, Series A 206 (2024).","ista":"Frankl P, Pach J, Pálvölgyi D. 2024. Odd-sunflowers. Journal of Combinatorial Theory, Series A. 206(8), 105889.","chicago":"Frankl, Peter, János Pach, and Dömötör Pálvölgyi. “Odd-Sunflowers.” <i>Journal of Combinatorial Theory, Series A</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">https://doi.org/10.1016/j.jcta.2024.105889</a>.","mla":"Frankl, Peter, et al. “Odd-Sunflowers.” <i>Journal of Combinatorial Theory, Series A</i>, vol. 206, no. 8, 105889, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">10.1016/j.jcta.2024.105889</a>.","ieee":"P. Frankl, J. Pach, and D. Pálvölgyi, “Odd-sunflowers,” <i>Journal of Combinatorial Theory, Series A</i>, vol. 206, no. 8. Elsevier, 2024.","ama":"Frankl P, Pach J, Pálvölgyi D. Odd-sunflowers. <i>Journal of Combinatorial Theory, Series A</i>. 2024;206(8). doi:<a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">10.1016/j.jcta.2024.105889</a>","apa":"Frankl, P., Pach, J., &#38; Pálvölgyi, D. (2024). Odd-sunflowers. <i>Journal of Combinatorial Theory, Series A</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jcta.2024.105889\">https://doi.org/10.1016/j.jcta.2024.105889</a>"},"intvolume":"       206","tmp":{"short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"oa_version":"Published Version","abstract":[{"text":"Extending the notion of sunflowers, we call a family of at least two sets an odd-sunflower if every element of the underlying set is contained in an odd number of sets or in none of them. It follows from the Erdős–Szemerédi conjecture, recently proved by Naslund and Sawin, that there is a constant <2 such that every family of subsets of an n-element set that contains no odd-sunflower consists of at most n sets. We construct such families of size at least 1.5021n. We also characterize minimal odd-sunflowers of triples.","lang":"eng"}],"corr_author":"1","language":[{"iso":"eng"}],"article_processing_charge":"No","oa":1,"article_number":"105889","scopus_import":"1","department":[{"_id":"HeEd"}],"isi":1,"ddc":["510"],"month":"08","issue":"8","fulldoi":"https://doi.org/10.1016/j.jcta.2024.105889","date_updated":"2025-09-04T13:20:39Z","file_date_updated":"2025-01-09T08:37:20Z","date_created":"2024-03-31T22:01:11Z","publication":"Journal of Combinatorial Theory, Series A","OA_place":"publisher","title":"Odd-sunflowers","has_accepted_license":"1","article_type":"original","file":[{"date_created":"2025-01-09T08:37:20Z","content_type":"application/pdf","checksum":"ffc29d65e712849f0d31009271e06a63","file_id":"18791","access_level":"open_access","relation":"main_file","creator":"dernst","success":1,"date_updated":"2025-01-09T08:37:20Z","file_name":"2024_JourCombiTheoryA_Frankl.pdf","file_size":366029}],"external_id":{"isi":["001217739200001"],"arxiv":["2310.16701"]},"OA_type":"hybrid","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","author":[{"full_name":"Frankl, Peter","last_name":"Frankl","first_name":"Peter"},{"id":"E62E3130-B088-11EA-B919-BF823C25FEA4","full_name":"Pach, János","first_name":"János","last_name":"Pach"},{"full_name":"Pálvölgyi, Dömötör","first_name":"Dömötör","last_name":"Pálvölgyi"}],"day":"01","arxiv":1},{"language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"}],"oa":1,"article_number":"109616","scopus_import":"1","department":[{"_id":"TaHa"}],"isi":1,"ddc":["510"],"quality_controlled":"1","volume":443,"doi":"10.1016/j.aim.2024.109616","acknowledgement":"Shiyu Shen has received funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413.","_id":"15248","date_published":"2024-05-01T00:00:00Z","status":"public","year":"2024","ec_funded":1,"publication_status":"published","publisher":"Elsevier","publication_identifier":{"eissn":["1090-2082"],"issn":["0001-8708"]},"citation":{"ama":"Shen S. Mirror symmetry for parabolic Higgs bundles via p-adic integration. <i>Advances in Mathematics</i>. 2024;443(5). doi:<a href=\"https://doi.org/10.1016/j.aim.2024.109616\">10.1016/j.aim.2024.109616</a>","apa":"Shen, S. (2024). Mirror symmetry for parabolic Higgs bundles via p-adic integration. <i>Advances in Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.aim.2024.109616\">https://doi.org/10.1016/j.aim.2024.109616</a>","chicago":"Shen, Shiyu. “Mirror Symmetry for Parabolic Higgs Bundles via P-Adic Integration.” <i>Advances in Mathematics</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.aim.2024.109616\">https://doi.org/10.1016/j.aim.2024.109616</a>.","mla":"Shen, Shiyu. “Mirror Symmetry for Parabolic Higgs Bundles via P-Adic Integration.” <i>Advances in Mathematics</i>, vol. 443, no. 5, 109616, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.aim.2024.109616\">10.1016/j.aim.2024.109616</a>.","ieee":"S. Shen, “Mirror symmetry for parabolic Higgs bundles via p-adic integration,” <i>Advances in Mathematics</i>, vol. 443, no. 5. Elsevier, 2024.","short":"S. Shen, Advances in Mathematics 443 (2024).","ista":"Shen S. 2024. Mirror symmetry for parabolic Higgs bundles via p-adic integration. Advances in Mathematics. 443(5), 109616."},"intvolume":"       443","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","abstract":[{"lang":"eng","text":"Applying the technique of p-adic integration, we prove the topological mirror symmetry conjecture of Hausel-Thaddeus for the moduli spaces of (strongly) parabolic Higgs bundles for the structure groups SLn and PGLn, building on previous work of Groechenig-Wyss-Ziegler on the non-parabolic case. We also prove the E-polynomial of the smooth moduli space of parabolic GLn-Higgs bundles is independent of the degree of the underlying vector bundles."}],"corr_author":"1","article_type":"original","file":[{"content_type":"application/pdf","checksum":"68f2f08136ccf547891a16a2c0621e97","file_id":"17315","date_created":"2024-07-22T12:10:03Z","file_size":702889,"file_name":"2024_AdvancesMath_Shen.pdf","date_updated":"2024-07-22T12:10:03Z","creator":"dernst","success":1,"access_level":"open_access","relation":"main_file"}],"external_id":{"arxiv":["2302.02817"],"isi":["001216128200001"]},"OA_type":"hybrid","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","day":"01","author":[{"last_name":"Shen","first_name":"Shiyu","id":"544cccd3-9005-11ec-87bc-94aef1c5b814","full_name":"Shen, Shiyu","orcid":"0000-0002-4444-8718"}],"arxiv":1,"month":"05","issue":"5","date_updated":"2025-09-04T13:21:18Z","fulldoi":"https://doi.org/10.1016/j.aim.2024.109616","file_date_updated":"2024-07-22T12:10:03Z","date_created":"2024-03-31T22:01:11Z","publication":"Advances in Mathematics","OA_place":"publisher","title":"Mirror symmetry for parabolic Higgs bundles via p-adic integration","has_accepted_license":"1"},{"article_type":"original","file":[{"date_created":"2024-04-02T08:42:17Z","content_type":"application/pdf","checksum":"1e65c40a71e565eebdc4c5ff11822ba2","file_id":"15255","creator":"dernst","success":1,"relation":"main_file","access_level":"open_access","date_updated":"2024-04-02T08:42:17Z","file_size":2626735,"file_name":"2024_MonthlyNRoyalAstronSoc_Matthee.pdf"}],"OA_type":"gold","external_id":{"isi":["001188770300019"],"arxiv":["2305.15346"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","arxiv":1,"page":"2794-2806","author":[{"first_name":"Jorryt J","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X"},{"last_name":"Golling","first_name":"Christopher","full_name":"Golling, Christopher"},{"last_name":"Mackenzie","first_name":"Ruari","full_name":"Mackenzie, Ruari"},{"full_name":"Pezzulli, Gabriele","first_name":"Gabriele","last_name":"Pezzulli"},{"last_name":"Lilly","first_name":"Simon","full_name":"Lilly, Simon"},{"full_name":"Schaye, Joop","last_name":"Schaye","first_name":"Joop"},{"full_name":"Bacon, Roland","last_name":"Bacon","first_name":"Roland"},{"full_name":"Kusakabe, Haruka","last_name":"Kusakabe","first_name":"Haruka"},{"full_name":"Urrutia, Tanya","last_name":"Urrutia","first_name":"Tanya"},{"full_name":"Boogaard, Leindert","last_name":"Boogaard","first_name":"Leindert"},{"full_name":"Brinchmann, Jarle","first_name":"Jarle","last_name":"Brinchmann"},{"first_name":"Michael V.","last_name":"Maseda","full_name":"Maseda, Michael V."},{"full_name":"Garel, Thibault","first_name":"Thibault","last_name":"Garel"},{"full_name":"Bouché, Nicolas F.","last_name":"Bouché","first_name":"Nicolas F."},{"full_name":"Wisotzki, Lutz","last_name":"Wisotzki","first_name":"Lutz"}],"day":"01","month":"04","issue":"3","file_date_updated":"2024-04-02T08:42:17Z","fulldoi":"https://doi.org/10.1093/mnras/stae673","date_updated":"2025-09-04T13:18:02Z","OA_place":"publisher","publication":"Monthly Notices of the Royal Astronomical Society","date_created":"2024-03-31T22:01:12Z","title":"Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field","has_accepted_license":"1","language":[{"iso":"eng"}],"oa":1,"department":[{"_id":"JoMa"}],"scopus_import":"1","article_processing_charge":"Yes","project":[{"name":"Young galaxies as tracers and agents of cosmic reionization","grant_number":"101076224","_id":"bd9b2118-d553-11ed-ba76-db24564edfea"}],"isi":1,"ddc":["520"],"doi":"10.1093/mnras/stae673","acknowledgement":"We thank the referee for constructive comments that helped improving the paper. Based on observations collected at the European Southern Observatory under ESO programme 1101.A-0127. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. GP acknowledges support from the Netherlands Research School for Astronomy (Nederlandse Onderzoekschool Voor Astronomie, NOVA). JB acknowledges financial support from the Fundação para a Ciência e a Tecnologia (FCT) through national funds PTDC/FIS-AST/4862/2020, work contract 2020.03379.CEECIND, and research grants UIDB/04434/2020 and UIDP/04434/2020. TU and LW acknowledge funding by the European Research Council through ERC-AdG SPECMAP-CGM, GA 101020943. TG is supported by the ERC Starting grant 757258 ‘TRIPLE’.","quality_controlled":"1","volume":529,"status":"public","year":"2024","_id":"15249","date_published":"2024-04-01T00:00:00Z","citation":{"apa":"Matthee, J. J., Golling, C., Mackenzie, R., Pezzulli, G., Lilly, S., Schaye, J., … Wisotzki, L. (2024). Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stae673\">https://doi.org/10.1093/mnras/stae673</a>","ama":"Matthee JJ, Golling C, Mackenzie R, et al. Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;529(3):2794-2806. doi:<a href=\"https://doi.org/10.1093/mnras/stae673\">10.1093/mnras/stae673</a>","mla":"Matthee, Jorryt J., et al. “Large-Scale Excess H I Absorption around z ≈ 4 Galaxies Detected in a Background Galaxy Spectrum in the MUSE EXtremely Deep Field.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 529, no. 3, Oxford University Press, 2024, pp. 2794–806, doi:<a href=\"https://doi.org/10.1093/mnras/stae673\">10.1093/mnras/stae673</a>.","ieee":"J. J. Matthee <i>et al.</i>, “Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 529, no. 3. Oxford University Press, pp. 2794–2806, 2024.","chicago":"Matthee, Jorryt J, Christopher Golling, Ruari Mackenzie, Gabriele Pezzulli, Simon Lilly, Joop Schaye, Roland Bacon, et al. “Large-Scale Excess H I Absorption around z ≈ 4 Galaxies Detected in a Background Galaxy Spectrum in the MUSE EXtremely Deep Field.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stae673\">https://doi.org/10.1093/mnras/stae673</a>.","ista":"Matthee JJ, Golling C, Mackenzie R, Pezzulli G, Lilly S, Schaye J, Bacon R, Kusakabe H, Urrutia T, Boogaard L, Brinchmann J, Maseda MV, Garel T, Bouché NF, Wisotzki L. 2024. Large-scale excess H I absorption around z ≈ 4 galaxies detected in a background galaxy spectrum in the MUSE eXtremely deep field. Monthly Notices of the Royal Astronomical Society. 529(3), 2794–2806.","short":"J.J. Matthee, C. Golling, R. Mackenzie, G. Pezzulli, S. Lilly, J. Schaye, R. Bacon, H. Kusakabe, T. Urrutia, L. Boogaard, J. Brinchmann, M.V. Maseda, T. Garel, N.F. Bouché, L. Wisotzki, Monthly Notices of the Royal Astronomical Society 529 (2024) 2794–2806."},"intvolume":"       529","publication_status":"published","publisher":"Oxford University Press","DOAJ_listed":"1","publication_identifier":{"issn":["0035-8711"],"eissn":["1365-2966"]},"corr_author":"1","abstract":[{"lang":"eng","text":"Observationally mapping the relation between galaxies and the intergalactic medium (IGM) is of key interest for studies of cosmic reionization. Diffuse hydrogen gas has typically been observed in H I Lyman-α (Lyα) absorption in the spectra of bright background quasars. However, it is important to extend these measurements to background galaxies as quasars become increasingly rare at high redshift and rarely probe closely separated sight lines. Here, we use deep integral field spectroscopy in the MUSE eXtremely Deep Field to demonstrate the measurement of the Lyα transmission at z ≈ 4 in absorption to a background galaxy at z = 4.77. The H I transmission is consistent with independent quasar sight lines at similar redshifts. Exploiting the high number of spectroscopic redshifts of faint galaxies (500 between z = 4.0–4.7 within a radius of 8 arcmin) that are tracers of the density field, we show that Lyα transmission is inversely correlated with galaxy density, i.e. transparent regions in the Lyα forest mark underdense regions at z ≈ 4. Due to large-scale clustering, galaxies are surrounded by excess H I absorption over the cosmic mean out to 4 cMpc/h70. We also find that redshifts from the peak of the Lyα line are typically offset from the systemic redshift by +170 km s−1. This work extends results from z ≈ 2–3 to higher redshifts and demonstrates the power of deep integral field spectroscopy to simultaneously measure the ionization structure of the IGM and the large-scale density field in the early Universe."}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version"},{"publication":"Proceedings of the National Academy of Sciences of the United States of America","date_created":"2024-03-31T22:01:12Z","has_accepted_license":"1","title":"Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport","issue":"13","month":"03","date_updated":"2025-09-04T13:19:02Z","fulldoi":"https://doi.org/10.1073/pnas.2319686121","file_date_updated":"2024-04-02T08:54:28Z","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","author":[{"full_name":"Boytsov, Danila","last_name":"Boytsov","first_name":"Danila"},{"first_name":"Gregor M.","last_name":"Madej","full_name":"Madej, Gregor M."},{"full_name":"Horn, Georg","first_name":"Georg","last_name":"Horn"},{"full_name":"Blaha, Nadine","last_name":"Blaha","first_name":"Nadine"},{"full_name":"Köcher, Thomas","first_name":"Thomas","last_name":"Köcher"},{"full_name":"Sitte, Harald H.","last_name":"Sitte","first_name":"Harald H."},{"first_name":"Daria E","last_name":"Siekhaus","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8323-8353","full_name":"Siekhaus, Daria E"},{"last_name":"Ziegler","first_name":"Christine","full_name":"Ziegler, Christine"},{"full_name":"Sandtner, Walter","last_name":"Sandtner","first_name":"Walter"},{"id":"3047D808-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9588-1389","full_name":"Roblek, Marko","last_name":"Roblek","first_name":"Marko"}],"day":"26","article_type":"original","file":[{"creator":"dernst","success":1,"access_level":"open_access","relation":"main_file","file_name":"2024_PNAS_Boytsov.pdf","date_updated":"2024-04-02T08:54:28Z","file_size":2483787,"date_created":"2024-04-02T08:54:28Z","content_type":"application/pdf","checksum":"06f9e60b1146a685d58bf33999422fa8","file_id":"15256"}],"external_id":{"pmid":["38507452"],"isi":["001206419000003"]},"publication_identifier":{"eissn":["1091-6490"]},"publication_status":"published","publisher":"National Academy of Sciences","intvolume":"       121","citation":{"short":"D. Boytsov, G.M. Madej, G. Horn, N. Blaha, T. Köcher, H.H. Sitte, D.E. Siekhaus, C. Ziegler, W. Sandtner, M. Roblek, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","ista":"Boytsov D, Madej GM, Horn G, Blaha N, Köcher T, Sitte HH, Siekhaus DE, Ziegler C, Sandtner W, Roblek M. 2024. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. Proceedings of the National Academy of Sciences of the United States of America. 121(13), e2319686121.","mla":"Boytsov, Danila, et al. “Orphan Lysosomal Solute Carrier MFSD1 Facilitates Highly Selective Dipeptide Transport.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 13, e2319686121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2319686121\">10.1073/pnas.2319686121</a>.","chicago":"Boytsov, Danila, Gregor M. Madej, Georg Horn, Nadine Blaha, Thomas Köcher, Harald H. Sitte, Daria E Siekhaus, Christine Ziegler, Walter Sandtner, and Marko Roblek. “Orphan Lysosomal Solute Carrier MFSD1 Facilitates Highly Selective Dipeptide Transport.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2319686121\">https://doi.org/10.1073/pnas.2319686121</a>.","ieee":"D. Boytsov <i>et al.</i>, “Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 13. National Academy of Sciences, 2024.","ama":"Boytsov D, Madej GM, Horn G, et al. Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(13). doi:<a href=\"https://doi.org/10.1073/pnas.2319686121\">10.1073/pnas.2319686121</a>","apa":"Boytsov, D., Madej, G. M., Horn, G., Blaha, N., Köcher, T., Sitte, H. H., … Roblek, M. (2024). Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2319686121\">https://doi.org/10.1073/pnas.2319686121</a>"},"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"abstract":[{"lang":"eng","text":"Orphan solute carrier (SLC) represents a group of membrane transporters whose exact functions and substrate specificities are not known. Elucidating the function and regulation of orphan SLC transporters is not only crucial for advancing our knowledge of cellular and molecular biology but can potentially lead to the development of new therapeutic strategies. Here, we provide evidence for the biological function of a ubiquitous orphan lysosomal SLC, the Major Facilitator Superfamily Domain-containing Protein 1 (MFSD1), which has remained phylogenetically unassigned. Targeted metabolomics revealed that dipeptides containing either lysine or arginine residues accumulate in lysosomes of cells lacking MFSD1. Whole-cell patch-clamp electrophysiological recordings of HEK293-cells expressing MFSD1 on the cell surface displayed transport affinities for positively charged dipeptides in the lower mM range, while dipeptides that carry a negative net charge were not transported. This was also true for single amino acids and tripeptides, which MFSD1 failed to transport. Our results identify MFSD1 as a highly selective lysosomal lysine/arginine/histidine-containing dipeptide exporter, which functions as a uniporter."}],"corr_author":"1","quality_controlled":"1","volume":121,"acknowledgement":"We thank the Metabolomics Facility at Vienna BioCenter Core Facilities, which is a member of the Vienna BioCenter and funded by the City of Vienna through the Vienna Business Agency (shared research facility), for the LC–MS/MS analysis; and the BioImaging Facility at IST Austria for technical support and assistance. The authors want to thank N. Kastner for help with the live  cell  imaging  and  A.  Korošec  for  help  with  flow  cytometry.  This  work  was  supported by the Austrian Science Fund (FWF), grant P 36621- B (to M.R.), grant P 36667 (to W.S.), and core funding from IST Austria (to D.S.).","doi":"10.1073/pnas.2319686121","date_published":"2024-03-26T00:00:00Z","_id":"15250","year":"2024","status":"public","isi":1,"ddc":["570"],"language":[{"iso":"eng"}],"pmid":1,"article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","department":[{"_id":"DaSi"}],"article_number":"e2319686121","oa":1,"acknowledged_ssus":[{"_id":"Bio"}]}]