[{"date_updated":"2025-09-09T11:41:12Z","scopus_import":"1","abstract":[{"text":"Background: Human induced pluripotent stem cells represent a scalable source of youthful tissue progenitors and secretomes for regenerative therapies. The aim of our study was to investigate the potential of conditioned medium (CM) from hiPSC-mesenchymal progenitors (hiPSC-MPs) to stimulate osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells (MSCs). We also investigated whether prolonged cultivation or osteogenic pre-differentiation of hiPSC-MPs could enhance the stimulatory activity of CM.\r\nMethods: MSCs were isolated from 13 donors (age 20–90 years). CM derived from hiPSC-MPs was added to the MSC cultures and the effects on proliferation and osteogenic differentiation were examined after 14 days and 6 weeks. The stimulatory activity of hiPSC-MP-CM was compared with the activity of MSC-derived CM and with the activity of CM prepared from hiPSC-MPs pre-cultured in growth or osteogenic medium for 14 days. Comparative proteomic analysis of CM was performed to gain insight into the molecular components responsible for the stimulatory activity.\r\nResults: Primary bone marrow-derived MSC exhibited variability, with a tendency towards lower proliferation and tri-lineage differentiation in older donors. hiPSC-MP-CM increased the proliferation and alkaline phosphatase activity of MSC from several adult/aged donors after 14 days of continuous supplementation under osteogenic conditions. However, CM supplementation failed to improve the mineralization of MSC pellets after 6 weeks under osteogenic conditions. hiPSC-MP-CM showed greater enhancement of proliferation and ALP activity than CM derived from bone marrow-derived MSCs. Moreover, 14-day cultivation but not osteogenic pre-differentiation of hiPSC-MPs strongly enhanced CM stimulatory activity. Quantitative proteomic analysis of d14-CM revealed a distinct profile of components that formed a highly interconnected associations network with two clusters, one functionally associated with binding and organization of actin/cytoskeletal components and the other with structural constituents of the extracellular matrix, collagen, and growth factor binding. Several hub proteins were identified that were reported to have functions in cell-extracellular matrix interaction, osteogenic differentiation and development.\r\nConclusions: Our data show that hiPSC-MP-CM enhances early osteogenic differentiation of human bone marrow-derived MSCs and that prolonged cultivation of hiPSC-MPs enhances CM-stimulatory activity. Proteomic analysis of the upregulated protein components provides the basis for further optimization of hiPSC-MP-CM for bone regenerative therapies.","lang":"eng"}],"article_processing_charge":"Yes","_id":"18581","citation":{"mla":"Marolt Presen, Darja, et al. “Prolonged Cultivation Enhances the Stimulatory Activity of HiPSC Mesenchymal Progenitor-Derived Conditioned Medium.” <i>Stem Cell Research and Therapy</i>, vol. 15, 434, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1186/s13287-024-03960-5\">10.1186/s13287-024-03960-5</a>.","ista":"Marolt Presen D, Goeschl V, Hanetseder D, Ogrin L, Stetco AL, Tansek A, Pozenel L, Bruszel B, Mitulovic G, Oesterreicher J, Zipperle J, Schaedl B, Holnthoner W, Grillari J, Redl H. 2024. Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium. Stem Cell Research and Therapy. 15, 434.","short":"D. Marolt Presen, V. Goeschl, D. Hanetseder, L. Ogrin, A.L. Stetco, A. Tansek, L. Pozenel, B. Bruszel, G. Mitulovic, J. Oesterreicher, J. Zipperle, B. Schaedl, W. Holnthoner, J. Grillari, H. Redl, Stem Cell Research and Therapy 15 (2024).","ama":"Marolt Presen D, Goeschl V, Hanetseder D, et al. Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium. <i>Stem Cell Research and Therapy</i>. 2024;15. doi:<a href=\"https://doi.org/10.1186/s13287-024-03960-5\">10.1186/s13287-024-03960-5</a>","ieee":"D. Marolt Presen <i>et al.</i>, “Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium,” <i>Stem Cell Research and Therapy</i>, vol. 15. Springer Nature, 2024.","chicago":"Marolt Presen, Darja, Vanessa Goeschl, Dominik Hanetseder, Laura Ogrin, Alexandra Larissa Stetco, Anja Tansek, Laura Pozenel, et al. “Prolonged Cultivation Enhances the Stimulatory Activity of HiPSC Mesenchymal Progenitor-Derived Conditioned Medium.” <i>Stem Cell Research and Therapy</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1186/s13287-024-03960-5\">https://doi.org/10.1186/s13287-024-03960-5</a>.","apa":"Marolt Presen, D., Goeschl, V., Hanetseder, D., Ogrin, L., Stetco, A. L., Tansek, A., … Redl, H. (2024). Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium. <i>Stem Cell Research and Therapy</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s13287-024-03960-5\">https://doi.org/10.1186/s13287-024-03960-5</a>"},"article_type":"original","external_id":{"pmid":["39551765"],"isi":["001356479400001"]},"acknowledgement":"We thank the personnel of the Lorenz-Böhler-Unfallkrankenhaus for providing the human tissue waste for primary cell isolation and the New York Stem Cell Foundation Research Institute for providing the human induced pluripotent stem cell line 1013 A and its mesenchymal progenitors. We also thank all our colleagues at the Ludwig Boltzmann Institute for Traumatology for their suggestions and ongoing support of the project. InstaText writing tool (https://instatext.io) was used to edit the English language of the final manuscript.\r\nThis work has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie actions (grant agreement No. 657716) and the Transforming European Industry call H2020-NMBP-TRIND-2020 (grant agreement No. 953134), as well as by the FFG Industrienahe Dissertation program (grant agreement No. 867803 and 853056), the FEMtech Praktika program (grant agreement No. 852154, 868917 and 877951) and the Production of the Future program (grant agreement No. 877452).","date_created":"2024-11-24T23:01:47Z","doi":"10.1186/s13287-024-03960-5","article_number":"434","date_published":"2024-12-01T00:00:00Z","publication":"Stem Cell Research and Therapy","publisher":"Springer Nature","file":[{"date_updated":"2024-12-10T08:28:17Z","file_size":6690494,"creator":"dernst","relation":"main_file","file_name":"2024_StemCellResearch_Presen.pdf","success":1,"checksum":"91edba8edde30d781dce89fdd5cadc39","access_level":"open_access","file_id":"18641","date_created":"2024-12-10T08:28:17Z","content_type":"application/pdf"}],"day":"01","publication_identifier":{"eissn":["1757-6512"]},"type":"journal_article","OA_type":"gold","year":"2024","month":"12","department":[{"_id":"LifeSc"}],"author":[{"full_name":"Marolt Presen, Darja","first_name":"Darja","last_name":"Marolt Presen"},{"full_name":"Goeschl, Vanessa","first_name":"Vanessa","last_name":"Goeschl"},{"first_name":"Dominik","full_name":"Hanetseder, Dominik","last_name":"Hanetseder"},{"first_name":"Laura","full_name":"Ogrin, Laura","last_name":"Ogrin"},{"first_name":"Alexandra Larissa","full_name":"Stetco, Alexandra Larissa","last_name":"Stetco"},{"last_name":"Tansek","first_name":"Anja","full_name":"Tansek, Anja"},{"first_name":"Laura","full_name":"Pozenel, Laura","last_name":"Pozenel"},{"id":"70abbbb3-88ea-11ec-8e0a-e8c939944834","last_name":"Bruszel","full_name":"Bruszel, Bella","first_name":"Bella"},{"full_name":"Mitulovic, Goran","first_name":"Goran","last_name":"Mitulovic"},{"full_name":"Oesterreicher, Johannes","first_name":"Johannes","last_name":"Oesterreicher"},{"full_name":"Zipperle, Johannes","first_name":"Johannes","last_name":"Zipperle"},{"last_name":"Schaedl","first_name":"Barbara","full_name":"Schaedl, Barbara"},{"last_name":"Holnthoner","first_name":"Wolfgang","full_name":"Holnthoner, Wolfgang"},{"last_name":"Grillari","full_name":"Grillari, Johannes","first_name":"Johannes"},{"last_name":"Redl","full_name":"Redl, Heinz","first_name":"Heinz"}],"has_accepted_license":"1","intvolume":"        15","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"OA_place":"publisher","isi":1,"ddc":["570"],"status":"public","pmid":1,"oa":1,"quality_controlled":"1","publication_status":"published","file_date_updated":"2024-12-10T08:28:17Z","title":"Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Published Version","volume":15,"DOAJ_listed":"1"},{"oa":1,"pmid":1,"isi":1,"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","status":"public","ddc":["580"],"has_accepted_license":"1","intvolume":"        15","author":[{"full_name":"Luschnig, Christian","first_name":"Christian","last_name":"Luschnig"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jiří","first_name":"Jiří"}],"oa_version":"Published Version","DOAJ_listed":"1","volume":15,"title":"Over 25 years of decrypting PIN-mediated plant development","corr_author":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","language":[{"iso":"eng"}],"file_date_updated":"2024-12-03T14:10:54Z","publication_status":"published","quality_controlled":"1","acknowledgement":"We gratefully acknowledge Leo Gälweiler for authorizing his PIN1 story. We would like to thank Yuanrong Pei for invaluable help with preparing figures. Work in the lab of C.L. is supported by grants from the Austrian Science Fund (PAT 8419423) and by the Gesellschaft für Forschungsförderung Niederösterreich m.b.H. (FTI19-008). The lab of J.F. is supported by the Austrian Science Fund (I 6123-B and P 37051-B).","external_id":{"isi":["001356232600004"],"pmid":["39548100"]},"date_created":"2024-11-24T23:01:48Z","article_type":"original","doi":"10.1038/s41467-024-54240-y","article_processing_charge":"Yes","citation":{"ista":"Luschnig C, Friml J. 2024. Over 25 years of decrypting PIN-mediated plant development. Nature Communications. 15, 9904.","mla":"Luschnig, Christian, and Jiří Friml. “Over 25 Years of Decrypting PIN-Mediated Plant Development.” <i>Nature Communications</i>, vol. 15, 9904, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-54240-y\">10.1038/s41467-024-54240-y</a>.","short":"C. Luschnig, J. Friml, Nature Communications 15 (2024).","ieee":"C. Luschnig and J. Friml, “Over 25 years of decrypting PIN-mediated plant development,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","ama":"Luschnig C, Friml J. Over 25 years of decrypting PIN-mediated plant development. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-54240-y\">10.1038/s41467-024-54240-y</a>","chicago":"Luschnig, Christian, and Jiří Friml. “Over 25 Years of Decrypting PIN-Mediated Plant Development.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-54240-y\">https://doi.org/10.1038/s41467-024-54240-y</a>.","apa":"Luschnig, C., &#38; Friml, J. (2024). Over 25 years of decrypting PIN-mediated plant development. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-54240-y\">https://doi.org/10.1038/s41467-024-54240-y</a>"},"_id":"18582","abstract":[{"lang":"eng","text":"Identification of PIN exporters for auxin, the major coordinative signal in plants, some 25 years ago, signifies a landmark in our understanding of plant-specific mechanisms underlying development and adaptation. Auxin is directionally transported throughout the plant body; a unique feature already envisioned by Darwin and solidified by PINs’ discovery and characterization. The PIN-based auxin distribution network with its complex regulations of PIN expression, localization and activity turned out to underlie a remarkable multitude of developmental processes and represents means to integrate endogenous and environmental signals. Given the recent anniversary, we here summarize past and current developments in this exciting field."}],"date_updated":"2025-09-08T14:53:48Z","scopus_import":"1","month":"12","department":[{"_id":"JiFr"}],"year":"2024","type":"journal_article","OA_type":"gold","publication_identifier":{"eissn":["2041-1723"]},"day":"01","project":[{"name":"Peptide receptors for auxin canalization in Arabidopsis","_id":"bd76d395-d553-11ed-ba76-f678c14f9033","grant_number":"I06123"},{"grant_number":"P37051","name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors","_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6"}],"date_published":"2024-12-01T00:00:00Z","article_number":"9904","publisher":"Springer Nature","file":[{"checksum":"3a31af06f52100d287f1e9d9c2aa1d40","access_level":"open_access","success":1,"content_type":"application/pdf","file_id":"18615","date_created":"2024-12-03T14:10:54Z","relation":"main_file","creator":"dernst","date_updated":"2024-12-03T14:10:54Z","file_size":1426555,"file_name":"2024_NatureComm_Luschnig.pdf"}],"publication":"Nature Communications"},{"file_date_updated":"2024-12-10T08:10:39Z","publication_status":"published","quality_controlled":"1","oa_version":"Published Version","volume":110,"title":"Partitioning problems via random processes","corr_author":"1","arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"has_accepted_license":"1","intvolume":"       110","issue":"6","author":[{"id":"0b2a4358-bb35-11ec-b7b9-e3279b593dbb","last_name":"Anastos","full_name":"Anastos, Michael","first_name":"Michael"},{"first_name":"Oliver","full_name":"Cooley, Oliver","last_name":"Cooley","id":"43f4ddd0-a46b-11ec-8df6-ef3703bd721d"},{"last_name":"Kang","full_name":"Kang, Mihyun","first_name":"Mihyun"},{"orcid":"0000-0002-4003-7567","last_name":"Kwan","id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3","first_name":"Matthew Alan","full_name":"Kwan, Matthew Alan"}],"oa":1,"isi":1,"OA_place":"publisher","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","ddc":["510"],"day":"01","article_number":"e70010","date_published":"2024-12-01T00:00:00Z","project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"},{"name":"Randomness and structure in combinatorics","_id":"bd95085b-d553-11ed-ba76-e55d3349be45","grant_number":"101076777"}],"file":[{"file_size":539891,"date_updated":"2024-12-10T08:10:39Z","relation":"main_file","creator":"dernst","file_name":"2024_JournLondonMathSoc_Anastos.pdf","success":1,"checksum":"98e301e0565d75e3fb50e10e982a5018","access_level":"open_access","file_id":"18639","date_created":"2024-12-10T08:10:39Z","content_type":"application/pdf"}],"publisher":"Wiley","publication":"Journal of the London Mathematical Society","department":[{"_id":"MaKw"}],"month":"12","year":"2024","OA_type":"hybrid","type":"journal_article","publication_identifier":{"issn":["0024-6107"],"eissn":["1469-7750"]},"abstract":[{"text":"There are a number of well-known problems and conjectures about partitioning graphs to satisfy local constraints. For example, the majority colouring conjecture of Kreutzer, Oum, Seymour, van der Zypen and Wood states that every directed graph has a 3-colouring such that for every vertex v, at most half of the out-neighbours of v have the same colour as \r\n. As another example, the internal partition conjecture, due to DeVos and to Ban and Linial, states that for every d, all but finitely many d-regular graphs have a partition into two non-empty parts such that for every vertex v, at least half of the neighbours of v lie in the same part as v. We prove several results in this spirit: in particular, two of our results are that the majority colouring conjecture holds for Erdős–Rényi random directed graphs (of any density), and that the internal partition conjecture holds if we permit a tiny number of ‘exceptional vertices’. Our proofs involve a variety of techniques, including several different methods to analyse random recolouring processes. One highlight is a personality-changing scheme: we ‘forget’ certain information based on the state of a Markov chain, giving us more independence to work with.","lang":"eng"}],"date_updated":"2025-12-02T13:52:26Z","scopus_import":"1","external_id":{"isi":["001374738100001"],"arxiv":["2307.06453"]},"ec_funded":1,"acknowledgement":"We are grateful to the anonymous referees for their thorough reading of the paper, and for many suggestions which have improved the exposition throughout.\r\n\r\nMichael Anastos was supported by the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 101034413. Matthew Kwan was supported by ERC Starting Grant ‘RANDSTRUCT’ No. 101076777, also funded by the European Union image. Mihyun Kang was supported in part by the Austrian Science Fund (FWF) [10.55776/I6502]. For the purpose of open access, the authors have applied a CC-BY public copyright licence to any Author Accepted Manuscript version arising from this submission.","date_created":"2024-11-24T23:01:48Z","article_type":"original","doi":"10.1112/jlms.70010","article_processing_charge":"Yes (via OA deal)","citation":{"apa":"Anastos, M., Cooley, O., Kang, M., &#38; Kwan, M. A. (2024). Partitioning problems via random processes. <i>Journal of the London Mathematical Society</i>. Wiley. <a href=\"https://doi.org/10.1112/jlms.70010\">https://doi.org/10.1112/jlms.70010</a>","chicago":"Anastos, Michael, Oliver Cooley, Mihyun Kang, and Matthew Alan Kwan. “Partitioning Problems via Random Processes.” <i>Journal of the London Mathematical Society</i>. Wiley, 2024. <a href=\"https://doi.org/10.1112/jlms.70010\">https://doi.org/10.1112/jlms.70010</a>.","ama":"Anastos M, Cooley O, Kang M, Kwan MA. Partitioning problems via random processes. <i>Journal of the London Mathematical Society</i>. 2024;110(6). doi:<a href=\"https://doi.org/10.1112/jlms.70010\">10.1112/jlms.70010</a>","ieee":"M. Anastos, O. Cooley, M. Kang, and M. A. Kwan, “Partitioning problems via random processes,” <i>Journal of the London Mathematical Society</i>, vol. 110, no. 6. Wiley, 2024.","short":"M. Anastos, O. Cooley, M. Kang, M.A. Kwan, Journal of the London Mathematical Society 110 (2024).","mla":"Anastos, Michael, et al. “Partitioning Problems via Random Processes.” <i>Journal of the London Mathematical Society</i>, vol. 110, no. 6, e70010, Wiley, 2024, doi:<a href=\"https://doi.org/10.1112/jlms.70010\">10.1112/jlms.70010</a>.","ista":"Anastos M, Cooley O, Kang M, Kwan MA. 2024. Partitioning problems via random processes. Journal of the London Mathematical Society. 110(6), e70010."},"_id":"18583"},{"year":"2024","department":[{"_id":"JoMa"}],"month":"11","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"OA_type":"gold","type":"journal_article","day":"14","publication":"Astrophysical Journal","publisher":"IOP Publishing","file":[{"file_id":"18640","date_created":"2024-12-10T08:18:53Z","content_type":"application/pdf","success":1,"checksum":"dcd854acee73ce998d70a4ce634ead6d","access_level":"open_access","file_name":"2024_AstrophysicalJournal_Suess.pdf","file_size":13352667,"date_updated":"2024-12-10T08:18:53Z","relation":"main_file","creator":"dernst"}],"article_number":"101","date_published":"2024-11-14T00:00:00Z","doi":"10.3847/1538-4357/ad75fe","article_type":"original","external_id":{"isi":["001355710500001"],"arxiv":["2404.13132"]},"date_created":"2024-11-24T23:01:48Z","acknowledgement":"K.A.S. thanks Shelly Meyett, the MegaScience Program Coordinator, for invaluable assistance designing WOPR 88967 and ensuring that this program was fully observed. This proposal was conceived of and developed at the International Space Science Institute (ISSI) in Bern, through ISSI International Team project #562. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The raw data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with JWST Cycle 2 GO program #4111, and this project has gratefully made use of a large number of public JWST programs in the A2744 field including JWST-GO-2641, JWST-ERS-1324, JWST-DD-2756, JWST-GO-2883, JWST-GO-3538, and JWST-GO-3516. Support for program JWST-GO-4111 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555.\r\n\r\nThe Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (\"ODIN\") and warmly thanks the European Commission's and University of Groningen's CO-FUND Rosalind Franklin program. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. The work of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation. T.B.M. was supported by a CIERA Fellowship. H.A. is supported by CNES, focused on the JWST mission, and by the Programme National Cosmology and Galaxies (PNCG) of CNRS/INSU with INP and IN2P3, co-funded by CEA and CNES. The BGU lensing group acknowledges support by grant No. 2020750 from the United States–Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF); by the Ministry of Science & Technology, Israel; and by the Israel Science Foundation grant No. 864/23. Y.F. acknowledges support from JSPS KAKENHI grant No. JP22K21349 and JP23K13149. R.P. and D.M. acknowledge funding from JWST-GO-02561.013 and JWST-GO-04111.035.","_id":"18584","citation":{"apa":"Suess, K. A., Weaver, J. R., Price, S. H., Pan, R., Wang, B., Bezanson, R., … Zitrin, A. (2024). Medium bands, mega science: A JWST/NIRCam medium-band imaging survey of A2744. <i>Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ad75fe\">https://doi.org/10.3847/1538-4357/ad75fe</a>","mla":"Suess, Katherine A., et al. “Medium Bands, Mega Science: A JWST/NIRCam Medium-Band Imaging Survey of A2744.” <i>Astrophysical Journal</i>, vol. 976, no. 1, 101, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/1538-4357/ad75fe\">10.3847/1538-4357/ad75fe</a>.","ista":"Suess KA, Weaver JR, Price SH, Pan R, Wang B, Bezanson R, Brammer G, Cutler SE, Labbé I, Leja J, Williams CC, Whitaker KE, Atek H, Dayal P, De Graaff A, Feldmann R, Franx M, Fudamoto Y, Fujimoto S, Furtak LJ, Goulding AD, Greene JE, Khullar G, Kokorev V, Kriek M, Lorenz B, Marchesini D, Maseda MV, Matthee JJ, Miller TB, Mitsuhashi I, Mowla LA, Muzzin A, Naidu RP, Nanayakkara T, Nelson EJ, Oesch PA, Setton DJ, Shipley H, Smit R, Spilker JS, Van Dokkum P, Zitrin A. 2024. Medium bands, mega science: A JWST/NIRCam medium-band imaging survey of A2744. Astrophysical Journal. 976(1), 101.","short":"K.A. Suess, J.R. Weaver, S.H. Price, R. Pan, B. Wang, R. Bezanson, G. Brammer, S.E. Cutler, I. Labbé, J. Leja, C.C. Williams, K.E. Whitaker, H. Atek, P. Dayal, A. De Graaff, R. Feldmann, M. Franx, Y. Fudamoto, S. Fujimoto, L.J. Furtak, A.D. Goulding, J.E. Greene, G. Khullar, V. Kokorev, M. Kriek, B. Lorenz, D. Marchesini, M.V. Maseda, J.J. Matthee, T.B. Miller, I. Mitsuhashi, L.A. Mowla, A. Muzzin, R.P. Naidu, T. Nanayakkara, E.J. Nelson, P.A. Oesch, D.J. Setton, H. Shipley, R. Smit, J.S. Spilker, P. Van Dokkum, A. Zitrin, Astrophysical Journal 976 (2024).","chicago":"Suess, Katherine A., John R. Weaver, Sedona H. Price, Richard Pan, Bingjie Wang, Rachel Bezanson, Gabriel Brammer, et al. “Medium Bands, Mega Science: A JWST/NIRCam Medium-Band Imaging Survey of A2744.” <i>Astrophysical Journal</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/1538-4357/ad75fe\">https://doi.org/10.3847/1538-4357/ad75fe</a>.","ieee":"K. A. Suess <i>et al.</i>, “Medium bands, mega science: A JWST/NIRCam medium-band imaging survey of A2744,” <i>Astrophysical Journal</i>, vol. 976, no. 1. IOP Publishing, 2024.","ama":"Suess KA, Weaver JR, Price SH, et al. Medium bands, mega science: A JWST/NIRCam medium-band imaging survey of A2744. <i>Astrophysical Journal</i>. 2024;976(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ad75fe\">10.3847/1538-4357/ad75fe</a>"},"article_processing_charge":"Yes","abstract":[{"text":"In this paper, we describe the \"Medium Bands, Mega Science\" JWST Cycle 2 survey (JWST-GO-4111) and demonstrate the power of these data to reveal both the spatially integrated and spatially resolved properties of galaxies from the local Universe to the era of cosmic dawn. Executed in 2023 November, MegaScience obtained ∼30 arcmin2 of deep multiband NIRCam imaging centered on the z ∼ 0.3 A2744 cluster, including 11 medium-band filters and the two shortest-wavelength broadband filters, F070W and F090W. Together, MegaScience and the UNCOVER Cycle 1 treasury program provide a complete set of deep (∼28–30 magAB) images in all NIRCam medium- and broadband filters. This unique data set allows us to precisely constrain photometric redshifts, map stellar populations and dust attenuation for large samples of distant galaxies, and examine the connection between galaxy structures and formation histories. MegaScience also includes ∼17 arcmin2 of NIRISS parallel imaging in two broadband and four medium-band filters from 0.9 to 4.8 μm, expanding the footprint where robust spectral energy distribution (SED) fitting is possible. We provide example SEDs and multiband cutouts at a variety of redshifts, and use a catalog of JWST spectroscopic redshifts to show that MegaScience improves both the scatter and catastrophic outlier rate of photometric redshifts by factors of 2–3. Additionally, we demonstrate the spatially resolved science enabled by MegaScience by presenting maps of the [O iii] line emission and continuum emission in three spectroscopically confirmed z > 6 galaxies. We show that line emission in reionization-era galaxies can be clumpy, extended, and spatially offset from continuum emission, implying that galaxy assembly histories are complex even at these early epochs. We publicly release fully reduced mosaics and photometric catalogs for both the NIRCam primary and NIRISS parallel fields (jwst-uncover.github.io/megascience).","lang":"eng"}],"scopus_import":"1","date_updated":"2025-09-09T11:40:09Z","volume":976,"DOAJ_listed":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","arxiv":1,"title":"Medium bands, mega science: A JWST/NIRCam medium-band imaging survey of A2744","publication_status":"published","file_date_updated":"2024-12-10T08:18:53Z","quality_controlled":"1","oa":1,"ddc":["520"],"status":"public","OA_place":"publisher","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"isi":1,"intvolume":"       976","issue":"1","has_accepted_license":"1","author":[{"last_name":"Suess","first_name":"Katherine A.","full_name":"Suess, Katherine A."},{"first_name":"John R.","full_name":"Weaver, John R.","last_name":"Weaver"},{"full_name":"Price, Sedona H.","first_name":"Sedona H.","last_name":"Price"},{"full_name":"Pan, Richard","first_name":"Richard","last_name":"Pan"},{"last_name":"Wang","full_name":"Wang, Bingjie","first_name":"Bingjie"},{"first_name":"Rachel","full_name":"Bezanson, Rachel","last_name":"Bezanson"},{"last_name":"Brammer","full_name":"Brammer, Gabriel","first_name":"Gabriel"},{"last_name":"Cutler","first_name":"Sam E.","full_name":"Cutler, Sam E."},{"last_name":"Labbé","full_name":"Labbé, Ivo","first_name":"Ivo"},{"last_name":"Leja","full_name":"Leja, Joel","first_name":"Joel"},{"last_name":"Williams","first_name":"Christina C.","full_name":"Williams, Christina C."},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"},{"last_name":"Atek","first_name":"Hakim","full_name":"Atek, Hakim"},{"full_name":"Dayal, Pratika","first_name":"Pratika","last_name":"Dayal"},{"full_name":"De Graaff, Anna","first_name":"Anna","last_name":"De Graaff"},{"first_name":"Robert","full_name":"Feldmann, Robert","last_name":"Feldmann"},{"last_name":"Franx","first_name":"Marijn","full_name":"Franx, Marijn"},{"full_name":"Fudamoto, Yoshinobu","first_name":"Yoshinobu","last_name":"Fudamoto"},{"last_name":"Fujimoto","first_name":"Seiji","full_name":"Fujimoto, Seiji"},{"last_name":"Furtak","full_name":"Furtak, Lukas J.","first_name":"Lukas J."},{"last_name":"Goulding","first_name":"Andy D.","full_name":"Goulding, Andy D."},{"first_name":"Jenny E.","full_name":"Greene, Jenny E.","last_name":"Greene"},{"last_name":"Khullar","first_name":"Gourav","full_name":"Khullar, Gourav"},{"first_name":"Vasily","full_name":"Kokorev, Vasily","last_name":"Kokorev"},{"last_name":"Kriek","full_name":"Kriek, Mariska","first_name":"Mariska"},{"full_name":"Lorenz, Brian","first_name":"Brian","last_name":"Lorenz"},{"first_name":"Danilo","full_name":"Marchesini, Danilo","last_name":"Marchesini"},{"first_name":"Michael V.","full_name":"Maseda, Michael V.","last_name":"Maseda"},{"first_name":"Jorryt J","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720"},{"full_name":"Miller, Tim B.","first_name":"Tim B.","last_name":"Miller"},{"last_name":"Mitsuhashi","full_name":"Mitsuhashi, Ikki","first_name":"Ikki"},{"first_name":"Lamiya A.","full_name":"Mowla, Lamiya A.","last_name":"Mowla"},{"full_name":"Muzzin, Adam","first_name":"Adam","last_name":"Muzzin"},{"last_name":"Naidu","full_name":"Naidu, Rohan P.","first_name":"Rohan P."},{"last_name":"Nanayakkara","full_name":"Nanayakkara, Themiya","first_name":"Themiya"},{"last_name":"Nelson","full_name":"Nelson, Erica J.","first_name":"Erica J."},{"full_name":"Oesch, Pascal A.","first_name":"Pascal A.","last_name":"Oesch"},{"full_name":"Setton, David J.","first_name":"David J.","last_name":"Setton"},{"full_name":"Shipley, Heath","first_name":"Heath","last_name":"Shipley"},{"first_name":"Renske","full_name":"Smit, Renske","last_name":"Smit"},{"full_name":"Spilker, Justin S.","first_name":"Justin S.","last_name":"Spilker"},{"full_name":"Van Dokkum, Pieter","first_name":"Pieter","last_name":"Van Dokkum"},{"last_name":"Zitrin","first_name":"Adi","full_name":"Zitrin, Adi"}]},{"isi":1,"OA_place":"publisher","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","ddc":["520"],"oa":1,"author":[{"first_name":"R. A.","full_name":"Meyer, R. A.","last_name":"Meyer"},{"first_name":"P. A.","full_name":"Oesch, P. A.","last_name":"Oesch"},{"full_name":"Giovinazzo, E.","first_name":"E.","last_name":"Giovinazzo"},{"last_name":"Weibel","first_name":"A.","full_name":"Weibel, A."},{"full_name":"Brammer, G.","first_name":"G.","last_name":"Brammer"},{"full_name":"Matthee, Jorryt J","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","orcid":"0000-0003-2871-127X","last_name":"Matthee"},{"last_name":"Naidu","full_name":"Naidu, R. P.","first_name":"R. P."},{"full_name":"Bouwens, R. J.","first_name":"R. J.","last_name":"Bouwens"},{"full_name":"Chisholm, J.","first_name":"J.","last_name":"Chisholm"},{"last_name":"Covelo-Paz","full_name":"Covelo-Paz, A.","first_name":"A."},{"last_name":"Fudamoto","first_name":"Y.","full_name":"Fudamoto, Y."},{"full_name":"Maseda, M.","first_name":"M.","last_name":"Maseda"},{"first_name":"E.","full_name":"Nelson, E.","last_name":"Nelson"},{"first_name":"I.","full_name":"Shivaei, I.","last_name":"Shivaei"},{"last_name":"Xiao","first_name":"M.","full_name":"Xiao, M."},{"first_name":"T.","full_name":"Herard-Demanche, T.","last_name":"Herard-Demanche"},{"full_name":"Illingworth, G. D.","first_name":"G. D.","last_name":"Illingworth"},{"last_name":"Kerutt","full_name":"Kerutt, J.","first_name":"J."},{"id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4","last_name":"Kramarenko","orcid":"0000-0001-5346-6048","full_name":"Kramarenko, Ivan","first_name":"Ivan"},{"first_name":"I.","full_name":"Labbe, I.","last_name":"Labbe"},{"last_name":"Leonova","full_name":"Leonova, E.","first_name":"E."},{"full_name":"Magee, D.","first_name":"D.","last_name":"Magee"},{"first_name":"J.","full_name":"Matharu, J.","last_name":"Matharu"},{"first_name":"G.","full_name":"Prieto Lyon, G.","last_name":"Prieto Lyon"},{"first_name":"N.","full_name":"Reddy, N.","last_name":"Reddy"},{"first_name":"D.","full_name":"Schaerer, D.","last_name":"Schaerer"},{"full_name":"Shapley, A.","first_name":"A.","last_name":"Shapley"},{"full_name":"Stefanon, M.","first_name":"M.","last_name":"Stefanon"},{"full_name":"Wozniak, M. A.","first_name":"M. A.","last_name":"Wozniak"},{"last_name":"Wuyts","full_name":"Wuyts, S.","first_name":"S."}],"has_accepted_license":"1","issue":"1","intvolume":"       535","title":"JWST FRESCO: A comprehensive census of H β + [O iii] emitters at 6.8 < z < 9.0 in the GOODS fields","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","page":"1067-1094","language":[{"iso":"eng"}],"oa_version":"Published Version","DOAJ_listed":"1","volume":535,"quality_controlled":"1","file_date_updated":"2024-12-03T12:52:13Z","publication_status":"published","article_processing_charge":"Yes","citation":{"mla":"Meyer, R. A., et al. “JWST FRESCO: A Comprehensive Census of H β + [O Iii] Emitters at 6.8 &#60; z &#60; 9.0 in the GOODS Fields.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 535, no. 1, Oxford University Press, 2024, pp. 1067–94, doi:<a href=\"https://doi.org/10.1093/mnras/stae2353\">10.1093/mnras/stae2353</a>.","ista":"Meyer RA, Oesch PA, Giovinazzo E, Weibel A, Brammer G, Matthee JJ, Naidu RP, Bouwens RJ, Chisholm J, Covelo-Paz A, Fudamoto Y, Maseda M, Nelson E, Shivaei I, Xiao M, Herard-Demanche T, Illingworth GD, Kerutt J, Kramarenko I, Labbe I, Leonova E, Magee D, Matharu J, Prieto Lyon G, Reddy N, Schaerer D, Shapley A, Stefanon M, Wozniak MA, Wuyts S. 2024. JWST FRESCO: A comprehensive census of H β + [O iii] emitters at 6.8 &#60; z &#60; 9.0 in the GOODS fields. Monthly Notices of the Royal Astronomical Society. 535(1), 1067–1094.","chicago":"Meyer, R. A., P. A. Oesch, E. Giovinazzo, A. Weibel, G. Brammer, Jorryt J Matthee, R. P. Naidu, et al. “JWST FRESCO: A Comprehensive Census of H β + [O Iii] Emitters at 6.8 &#60; z &#60; 9.0 in the GOODS Fields.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stae2353\">https://doi.org/10.1093/mnras/stae2353</a>.","ieee":"R. A. Meyer <i>et al.</i>, “JWST FRESCO: A comprehensive census of H β + [O iii] emitters at 6.8 &#60; z &#60; 9.0 in the GOODS fields,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 535, no. 1. Oxford University Press, pp. 1067–1094, 2024.","ama":"Meyer RA, Oesch PA, Giovinazzo E, et al. JWST FRESCO: A comprehensive census of H β + [O iii] emitters at 6.8 &#60; z &#60; 9.0 in the GOODS fields. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;535(1):1067-1094. doi:<a href=\"https://doi.org/10.1093/mnras/stae2353\">10.1093/mnras/stae2353</a>","short":"R.A. Meyer, P.A. Oesch, E. Giovinazzo, A. Weibel, G. Brammer, J.J. Matthee, R.P. Naidu, R.J. Bouwens, J. Chisholm, A. Covelo-Paz, Y. Fudamoto, M. Maseda, E. Nelson, I. Shivaei, M. Xiao, T. Herard-Demanche, G.D. Illingworth, J. Kerutt, I. Kramarenko, I. Labbe, E. Leonova, D. Magee, J. Matharu, G. Prieto Lyon, N. Reddy, D. Schaerer, A. Shapley, M. Stefanon, M.A. Wozniak, S. Wuyts, Monthly Notices of the Royal Astronomical Society 535 (2024) 1067–1094.","apa":"Meyer, R. A., Oesch, P. A., Giovinazzo, E., Weibel, A., Brammer, G., Matthee, J. J., … Wuyts, S. (2024). JWST FRESCO: A comprehensive census of H β + [O iii] emitters at 6.8 &#60; z &#60; 9.0 in the GOODS fields. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stae2353\">https://doi.org/10.1093/mnras/stae2353</a>"},"_id":"18585","date_created":"2024-11-24T23:01:49Z","acknowledgement":"The authors thank the anonymous referee for comments and suggestions which improved this paper. RAM thanks R. Kannan for sharing emission line luminosities from THESAN and H. Katz for similar data from an early version of the SPHINX20 data release (we use the final data release in this paper). The authors thank the CONGRESS team for proposing and designing their program with a zero exclusive access period.\r\nRAM, PA, ACP, and AW acknowledge support from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. PA, AW, EG, and MX acknowledge support from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072. YF acknowledges support by JSPS KAKENHI grant number JP22K21349 and JP23K13149. RPN acknowledges support for this work provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. MS acknowledges support from the European Research Commission Grant 101088789 (SFEER), from the CIDEGENT/2021/059 grant by Generalitat Valenciana, and from project PID2019-109592GB-I00/AEI/10.13039/501100011033 by the Spanish Ministerio de Ciencia e Innovación - Agencia Estatal de Investigación. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant no. 140. Cloud-based data processing and file storage for this work is provided by the AWS Cloud Credits for Research program. RJB and MS acknowledges support from NWO grant TOP1.16.057.\r\nThis work is based on observations made with the NASA/ESA/CSA JWST. The raw data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with JWST Cycle 1 GO program #1895. Support for program JWST-GO-1895 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555.","external_id":{"isi":["001348009500001"]},"article_type":"original","doi":"10.1093/mnras/stae2353","date_updated":"2025-09-08T14:47:58Z","scopus_import":"1","abstract":[{"text":"We present the census of Hβ+[OIII] 4960,5008 Åemitters at 6.8<z<9.0 from the JWST FRESCO survey over 124 arcmin2 in the GOODS-North and GOODS-South fields. Our unbiased spectroscopic search results in 137 spectroscopically-confirmed galaxies at 6.8<z<9.0 with observed [OIII] fluxes f[OIII]≳1×10−18 ergs s−1 cm−2. The rest-frame optical line ratios of the median stacked spectrum (median MUV=−19.65+0.59−1.05) indicate negligible dust attenuation, low metallicity (12+log(O/H)=7.2−7.7) and a high ionisation parameter log10U≃−2.5. We find a factor ×1.3 difference in the number density of 6.8<z<9.0 galaxies between GOODS-South and GOODS-North, which is caused by a single overdensity at 7.0<z<7.2 in GOODS-North. The bright end of the UV luminosity function of spectroscopically-confirmed [OIII] emitters is in good agreement with HST dropout-selected samples. Discrepancies between the observed [OIII] LF, [OIII]/UV ratio and [OIII] equivalent widths, and that predicted by theoretical models, suggest burstier star-formation histories and/or more heterogeneous metallicity and ionising conditions in z>7 galaxies. We report a rapid decline of the [OIII] luminosity density at z≳6−7 which cannot be explained by the evolution of the cosmic star-formation rate density. Finally we find that FRESCO detects in only 2h galaxies likely accounting for ∼10−20% of the ionising budget at z=7−8 (assuming an escape fraction of 10%), raising the prospect of directly detecting a significant fraction of the sources of reionisation with JWST.","lang":"eng"}],"OA_type":"gold","type":"journal_article","publication_identifier":{"issn":["0035-8711"],"eissn":["1365-2966"]},"month":"11","department":[{"_id":"JoMa"}],"year":"2024","date_published":"2024-11-01T00:00:00Z","file":[{"success":1,"access_level":"open_access","checksum":"efe0ce3580e01459f3be78eb111b35a9","date_created":"2024-12-03T12:52:13Z","file_id":"18613","content_type":"application/pdf","date_updated":"2024-12-03T12:52:13Z","file_size":29476699,"creator":"dernst","relation":"main_file","file_name":"2024_MonthlyNRoyalAstronSoc_Meyer.pdf"}],"publisher":"Oxford University Press","publication":"Monthly Notices of the Royal Astronomical Society","day":"01"},{"year":"2024","month":"11","department":[{"_id":"VaKa"}],"publication_identifier":{"issn":["1980-0436"]},"OA_type":"green","type":"journal_article","day":"01","publication":"Alea","publisher":"Instituto Nacional de Matematica Pura e Aplicada","project":[{"grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"}],"date_published":"2024-11-01T00:00:00Z","doi":"10.30757/ALEA.V21-70","article_type":"original","external_id":{"isi":["001440992000003"],"arxiv":["2404.11700"]},"ec_funded":1,"date_created":"2024-11-24T23:01:49Z","acknowledgement":"ents. The authors are grateful to Agnieszka Zelerowicz and the anonymous referee\r\nfor useful comments. The first author is grateful to Minsung Kim for providing some references.\r\nThe first author has been supported by the European Union Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101034413. The second author has been supported by the NSF grant DMS 2246983.","_id":"18586","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2404.11700","open_access":"1"}],"citation":{"ista":"CZUDEK KS, Dolgopyat D. 2024. The central limit theorem and rate of mixing for simple random walks on the circle. Alea. 21(2), 1853–1865.","mla":"CZUDEK, Klaudiusz S., and Dmitry Dolgopyat. “The Central Limit Theorem and Rate of Mixing for Simple Random Walks on the Circle.” <i>Alea</i>, vol. 21, no. 2, Instituto Nacional de Matematica Pura e Aplicada, 2024, pp. 1853–65, doi:<a href=\"https://doi.org/10.30757/ALEA.V21-70\">10.30757/ALEA.V21-70</a>.","short":"K.S. CZUDEK, D. Dolgopyat, Alea 21 (2024) 1853–1865.","ama":"CZUDEK KS, Dolgopyat D. The central limit theorem and rate of mixing for simple random walks on the circle. <i>Alea</i>. 2024;21(2):1853-1865. doi:<a href=\"https://doi.org/10.30757/ALEA.V21-70\">10.30757/ALEA.V21-70</a>","ieee":"K. S. CZUDEK and D. Dolgopyat, “The central limit theorem and rate of mixing for simple random walks on the circle,” <i>Alea</i>, vol. 21, no. 2. Instituto Nacional de Matematica Pura e Aplicada, pp. 1853–1865, 2024.","chicago":"CZUDEK, Klaudiusz S, and Dmitry Dolgopyat. “The Central Limit Theorem and Rate of Mixing for Simple Random Walks on the Circle.” <i>Alea</i>. Instituto Nacional de Matematica Pura e Aplicada, 2024. <a href=\"https://doi.org/10.30757/ALEA.V21-70\">https://doi.org/10.30757/ALEA.V21-70</a>.","apa":"CZUDEK, K. S., &#38; Dolgopyat, D. (2024). The central limit theorem and rate of mixing for simple random walks on the circle. <i>Alea</i>. Instituto Nacional de Matematica Pura e Aplicada. <a href=\"https://doi.org/10.30757/ALEA.V21-70\">https://doi.org/10.30757/ALEA.V21-70</a>"},"article_processing_charge":"No","abstract":[{"text":"We prove the Central Limit Theorem and superpolynomial mixing for environment\r\nviewed from the particle process in quasi periodic Diophantine random environment. The main\r\ningredients are smoothness estimates for the solution of the Poisson equation and local limit asymptotics for certain accelerated walks.","lang":"eng"}],"scopus_import":"1","date_updated":"2025-09-08T14:48:42Z","volume":21,"oa_version":"Preprint","page":"1853-1865","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","arxiv":1,"title":"The central limit theorem and rate of mixing for simple random walks on the circle","publication_status":"published","quality_controlled":"1","oa":1,"status":"public","OA_place":"repository","isi":1,"intvolume":"        21","issue":"2","author":[{"first_name":"Klaudiusz S","full_name":"Czudek, Klaudiusz S","last_name":"Czudek","id":"5c0e116e-803f-11ed-ab7e-90d572405f20"},{"last_name":"Dolgopyat","first_name":"Dmitry","full_name":"Dolgopyat, Dmitry"}]},{"volume":53,"oa_version":"Published Version","language":[{"iso":"eng"}],"page":"347-350","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Toward a common interpretation of the 3Rs principles in animal research","publication_status":"published","file_date_updated":"2024-12-03T14:07:04Z","quality_controlled":"1","pmid":1,"oa":1,"status":"public","ddc":["570"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","isi":1,"intvolume":"        53","has_accepted_license":"1","author":[{"last_name":"Lauwereyns","first_name":"Jan","full_name":"Lauwereyns, Jan"},{"first_name":"Jeffrey","full_name":"Bajramovic, Jeffrey","last_name":"Bajramovic"},{"full_name":"Bert, Bettina","first_name":"Bettina","last_name":"Bert"},{"full_name":"Camenzind, Samuel","first_name":"Samuel","last_name":"Camenzind"},{"last_name":"De Kock","first_name":"Joery","full_name":"De Kock, Joery"},{"first_name":"Alisa","full_name":"Elezović, Alisa","last_name":"Elezović"},{"full_name":"Erden, Sevilay","first_name":"Sevilay","last_name":"Erden"},{"full_name":"Gonzalez-Uarquin, Fernando","first_name":"Fernando","last_name":"Gonzalez-Uarquin"},{"last_name":"Ulman","full_name":"Ulman, Yesim Isil","first_name":"Yesim Isil"},{"last_name":"Hoffmann","first_name":"Orsolya Ivett","full_name":"Hoffmann, Orsolya Ivett"},{"last_name":"Kitsara","first_name":"Maria","full_name":"Kitsara, Maria"},{"first_name":"Nikolaos","full_name":"Kostomitsopoulos, Nikolaos","last_name":"Kostomitsopoulos"},{"last_name":"Neuhaus","full_name":"Neuhaus, Winfried","first_name":"Winfried"},{"last_name":"Petit-Demouliere","first_name":"Benoit","full_name":"Petit-Demouliere, Benoit"},{"last_name":"Pollo","full_name":"Pollo, Simone","first_name":"Simone"},{"full_name":"Riso, Brígida","first_name":"Brígida","last_name":"Riso"},{"id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8","last_name":"Schober","full_name":"Schober, Sophie","first_name":"Sophie"},{"last_name":"Sotiropoulos","first_name":"Athanassia","full_name":"Sotiropoulos, Athanassia"},{"last_name":"Thomas","full_name":"Thomas, Aurélie","first_name":"Aurélie"},{"full_name":"Vitale, Augusto","first_name":"Augusto","last_name":"Vitale"},{"first_name":"Doris","full_name":"Wilflingseder, Doris","last_name":"Wilflingseder"},{"last_name":"Ahluwalia","full_name":"Ahluwalia, Arti","first_name":"Arti"}],"year":"2024","department":[{"_id":"PreCl"}],"month":"12","publication_identifier":{"eissn":["1548-4475"],"issn":["0093-7355"]},"type":"journal_article","OA_type":"hybrid","day":"01","publication":"Lab Animal","publisher":"Springer Nature","file":[{"file_name":"2024_LabAnimal_Lauwereyns.pdf","date_updated":"2024-12-03T14:07:04Z","file_size":967252,"creator":"dernst","relation":"main_file","date_created":"2024-12-03T14:07:04Z","file_id":"18614","content_type":"application/pdf","success":1,"access_level":"open_access","checksum":"67fc140f761581a291591f075e49b88d"}],"date_published":"2024-12-01T00:00:00Z","doi":"10.1038/s41684-024-01476-2","article_type":"letter_note","acknowledgement":"This publication is based upon work from the Ethics Crossover Group within the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139, supported by COST (European Cooperation in Science and Technology). We acknowledge the input and advice from Dr. Susanna Louhimies.","external_id":{"pmid":["39548348"],"isi":["001355264100001"]},"date_created":"2024-11-24T23:01:49Z","_id":"18587","citation":{"apa":"Lauwereyns, J., Bajramovic, J., Bert, B., Camenzind, S., De Kock, J., Elezović, A., … Ahluwalia, A. (2024). Toward a common interpretation of the 3Rs principles in animal research. <i>Lab Animal</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41684-024-01476-2\">https://doi.org/10.1038/s41684-024-01476-2</a>","short":"J. Lauwereyns, J. Bajramovic, B. Bert, S. Camenzind, J. De Kock, A. Elezović, S. Erden, F. Gonzalez-Uarquin, Y.I. Ulman, O.I. Hoffmann, M. Kitsara, N. Kostomitsopoulos, W. Neuhaus, B. Petit-Demouliere, S. Pollo, B. Riso, S. Schober, A. Sotiropoulos, A. Thomas, A. Vitale, D. Wilflingseder, A. Ahluwalia, Lab Animal 53 (2024) 347–350.","chicago":"Lauwereyns, Jan, Jeffrey Bajramovic, Bettina Bert, Samuel Camenzind, Joery De Kock, Alisa Elezović, Sevilay Erden, et al. “Toward a Common Interpretation of the 3Rs Principles in Animal Research.” <i>Lab Animal</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41684-024-01476-2\">https://doi.org/10.1038/s41684-024-01476-2</a>.","ama":"Lauwereyns J, Bajramovic J, Bert B, et al. Toward a common interpretation of the 3Rs principles in animal research. <i>Lab Animal</i>. 2024;53:347-350. doi:<a href=\"https://doi.org/10.1038/s41684-024-01476-2\">10.1038/s41684-024-01476-2</a>","ieee":"J. Lauwereyns <i>et al.</i>, “Toward a common interpretation of the 3Rs principles in animal research,” <i>Lab Animal</i>, vol. 53. Springer Nature, pp. 347–350, 2024.","mla":"Lauwereyns, Jan, et al. “Toward a Common Interpretation of the 3Rs Principles in Animal Research.” <i>Lab Animal</i>, vol. 53, Springer Nature, 2024, pp. 347–50, doi:<a href=\"https://doi.org/10.1038/s41684-024-01476-2\">10.1038/s41684-024-01476-2</a>.","ista":"Lauwereyns J, Bajramovic J, Bert B, Camenzind S, De Kock J, Elezović A, Erden S, Gonzalez-Uarquin F, Ulman YI, Hoffmann OI, Kitsara M, Kostomitsopoulos N, Neuhaus W, Petit-Demouliere B, Pollo S, Riso B, Schober S, Sotiropoulos A, Thomas A, Vitale A, Wilflingseder D, Ahluwalia A. 2024. Toward a common interpretation of the 3Rs principles in animal research. Lab Animal. 53, 347–350."},"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Many scientific breakthroughs have depended on animal research, yet the ethical concerns surrounding the use of animals in experimentation have long prompted discussions about humane treatment and responsible scientific practice. First articulated by Russell and Burch, the 3Rs Principles of Replacement, Reduction, and Refinement have gained widespread recognition as basic guidelines for animal research. Over time, the 3Rs have transcended the research community, influencing policy decisions, animal welfare advocacy and public perception of animal experimentation. Despite their broad acceptance, interpretations of the 3Rs vary substantially, shaping statutory frameworks at various levels, with both technical and practical impacts."}],"scopus_import":"1","date_updated":"2025-09-08T14:50:31Z"},{"file_date_updated":"2024-12-13T11:30:53Z","publication_status":"published","oa_version":"Published Version","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"61","language":[{"iso":"eng"}],"corr_author":"1","title":"Non equilibrium dynamics of driven individual particles and 3D printing across scales","has_accepted_license":"1","author":[{"last_name":"Mweka","id":"2a69ab4b-896a-11ed-bdf8-cb8641cf2b21","first_name":"Cecelia N","full_name":"Mweka, Cecelia N"}],"oa":1,"ddc":["530"],"status":"public","supervisor":[{"first_name":"Scott R","full_name":"Waitukaitis, Scott R","orcid":"0000-0002-2299-3176","last_name":"Waitukaitis","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jérémie A","full_name":"Palacci, Jérémie A","orcid":"0000-0002-7253-9465","last_name":"Palacci","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d"}],"OA_place":"publisher","day":"29","publisher":"Institute of Science and Technology Austria","file":[{"checksum":"054ed7a5e5ae6e7220e6bb37ea57a3c3","access_level":"open_access","success":1,"content_type":"application/pdf","file_id":"18597","date_created":"2024-11-28T12:50:32Z","relation":"main_file","creator":"cmweka","file_size":3836671,"date_updated":"2024-11-28T12:50:32Z","file_name":"Cecelia Mweka Master Thesis.pdf"},{"access_level":"closed","checksum":"7d7d9299f090d83e628d65d93116e8c2","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2024-11-28T12:51:43Z","file_id":"18598","creator":"cmweka","relation":"source_file","file_size":7068210,"date_updated":"2024-12-13T11:30:53Z","file_name":"Cecelia Mweka Master Thesis.docx"}],"alternative_title":["ISTA Master's Thesis"],"date_published":"2024-11-29T00:00:00Z","month":"11","department":[{"_id":"GradSch"}],"year":"2024","type":"dissertation","publication_identifier":{"issn":["2791-4585"]},"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"abstract":[{"text":"This thesis is an experimental work about two distinct research projects that evolved from a single project: non-equilibrium dynamics of an acoustically vibrated particle and microfabrication of particles with nano-scale 3D printing. The first project explores non equilibrium dynamics of a particle driven by ultrasonic vibrations. We design an experimental system consisting of an electromechanical vibration scheme to drive the particle’s vibrations and an imaging scheme to track its trajectories. We study the trajectories to determine how the particle’s dynamics evolve under the driven conditions, considering out of equilibrium systems in the context of equilibrium statistical mechanics. Using a Langevin framework and the Boltzmann factor, we characterize the particle’s dynamics as complex; the particle motion\r\nis not purely diffusive. We extract physical parameters like spring constant, effective temperature, damping coefficient and resonance frequency.\r\n\r\nIn the second project, we explore and develop techniques in the design and microfabrication of particles across scales. Microfabrication involves building structures at the micron or submicron scale. These designed miniaturized patterns, objects, or devices are useful in biophysics, pharmacology, medical biology, and nanotechnology. We specifically apply two-photon polymerization, a form of 3D nano printing. We print millimetric particles, characterizing different designs to evaluate and showcase the resolution, aspect ratio integrity and print quality of the printing process. We also design and fabricate a microsensor to deflect under applicable force of order 0.1 pN. We present fundamental concepts needed to design the microsensor, showcasing 3D printing at considerably smaller scales down to the µm or below.","lang":"eng"}],"date_updated":"2026-04-07T12:42:13Z","doi":"10.15479/at:ista:18588","date_created":"2024-11-27T09:12:02Z","acknowledgement":"I would like to acknowledge Scott Waitukaitis and Jérémie Palacci, for their supervision, and their extensive support of my learning. \r\n\r\nFor the beautiful characterization images used in this work, I would like to thank Dr. Daniel Grober, Samuel Hajek and Felix Pertl.\r\n\r\nThe Palacci group, particularly Malina Strugaru and Dan Grober, for their continuous guidance in decoding and following my streams of thought.\r\n\r\nTo the Waitukaitis group, for helping me find my footing in science, and making me feel at\r\nhome.\r\n\r\nTo the Nanofabrication Facility (NFF) at ISTA, for training me in significant aspects of my research. The MIBA Facility, and particularly Todor Asenov for consistently picking up the phone for my machining and designing needs.\r\n\r\nTo my friends, Mariana, Lenka, Aaron, Rebecca, Eavan who provided an ear, wine, and a lot more when I needed to vent, talk through my crises as well as experiment. For the walks, for the coffees, for reading through my work and providing edits, for dinners to take me out of blocks and binds and for cheering me on when it felt insurmountable. \r\n\r\nFinally, I am grateful to Griff and Fletcher, whose music helped me through several blocks, especially with my writing.\r\n\r\nMy science would not have been possible without the guidance, support and contributions of\r\nall these people, and more.","degree_awarded":"MS","citation":{"apa":"Mweka, C. N. (2024). <i>Non equilibrium dynamics of driven individual particles and 3D printing across scales</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:18588\">https://doi.org/10.15479/at:ista:18588</a>","mla":"Mweka, Cecelia N. <i>Non Equilibrium Dynamics of Driven Individual Particles and 3D Printing across Scales</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:18588\">10.15479/at:ista:18588</a>.","ista":"Mweka CN. 2024. Non equilibrium dynamics of driven individual particles and 3D printing across scales. Institute of Science and Technology Austria.","ieee":"C. N. Mweka, “Non equilibrium dynamics of driven individual particles and 3D printing across scales,” Institute of Science and Technology Austria, 2024.","short":"C.N. Mweka, Non Equilibrium Dynamics of Driven Individual Particles and 3D Printing across Scales, Institute of Science and Technology Austria, 2024.","chicago":"Mweka, Cecelia N. “Non Equilibrium Dynamics of Driven Individual Particles and 3D Printing across Scales.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:18588\">https://doi.org/10.15479/at:ista:18588</a>.","ama":"Mweka CN. Non equilibrium dynamics of driven individual particles and 3D printing across scales. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:18588\">10.15479/at:ista:18588</a>"},"_id":"18588","article_processing_charge":"No"},{"issue":"12","intvolume":"        17","has_accepted_license":"1","author":[{"full_name":"Králová, Michaela","first_name":"Michaela","last_name":"Králová"},{"last_name":"Kubalová","first_name":"Ivona","full_name":"Kubalová, Ivona"},{"first_name":"Jakub","full_name":"Hajný, Jakub","last_name":"Hajný"},{"first_name":"Karolina","full_name":"Kubiasova, Karolina","orcid":"0000-0001-5630-9419","last_name":"Kubiasova","id":"946011F4-3E71-11EA-860B-C7A73DDC885E"},{"first_name":"Karolína","full_name":"Vagaská, Karolína","last_name":"Vagaská"},{"full_name":"Ge, Zengxiang","first_name":"Zengxiang","id":"f43371a3-09ff-11eb-8013-bd0c6a2f6de8","last_name":"Ge","orcid":"0000-0001-9381-3577"},{"id":"35A03822-F248-11E8-B48F-1D18A9856A87","last_name":"Gallei","orcid":"0000-0003-1286-7368","full_name":"Gallei, Michelle C","first_name":"Michelle C"},{"full_name":"Semerádová, Hana","first_name":"Hana","id":"42FE702E-F248-11E8-B48F-1D18A9856A87","last_name":"Semerádová"},{"full_name":"Kuchařová, Anna","first_name":"Anna","last_name":"Kuchařová"},{"first_name":"Martin","full_name":"Hönig, Martin","last_name":"Hönig"},{"id":"2DB5D88C-D7B3-11E9-B8FD-7907E6697425","last_name":"Monzer","full_name":"Monzer, Aline","first_name":"Aline"},{"full_name":"Kovačik, Martin","first_name":"Martin","last_name":"Kovačik"},{"last_name":"Friml","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","full_name":"Friml, Jiří"},{"last_name":"Novák","full_name":"Novák, Ondřej","first_name":"Ondřej"},{"full_name":"Benková, Eva","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","orcid":"0000-0002-8510-9739"},{"last_name":"Ikeda","first_name":"Yoshihisa","full_name":"Ikeda, Yoshihisa"},{"last_name":"Zalabák","first_name":"David","full_name":"Zalabák, David"}],"pmid":1,"oa":1,"ddc":["580"],"status":"public","OA_place":"publisher","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"isi":1,"publication_status":"published","file_date_updated":"2024-12-03T11:08:09Z","quality_controlled":"1","volume":17,"oa_version":"Published Version","page":"1850-1865","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"A decoy receptor derived from alternative splicing fine-tunes cytokinin signaling in Arabidopsis","abstract":[{"text":"Hormone perception and signaling pathways have a fundamental regulatory function in the physiological processes of plants. Cytokinins, a class of plant hormones, regulate cell division and meristem maintenance. The cytokinin signaling pathway is well established in the model plant Arabidopsis thaliana. Several negative feedback mechanisms, tightly controlling cytokinin signaling output, have been described previously. In this study, we identified a new feedback mechanism executed through alternative splicing of the cytokinin receptor AHK4/CRE1. A novel splicing variant named CRE1int7 results from seventh intron retention, introducing a premature termination codon in the transcript. We showed that CRE1int7 is translated in planta into a truncated receptor lacking the C-terminal receiver domain essential for signal transduction. CRE1int7 can bind cytokinin but cannot activate the downstream cascade. We present a novel negative feedback mechanism of the cytokinin signaling pathway, facilitated by a decoy receptor that can inactivate canonical cytokinin receptors via dimerization and compete with them for ligand binding. Ensuring proper plant growth and development requires precise control of the cytokinin signaling pathway at several levels. CRE1int7 represents a so-far unknown mechanism for fine-tuning the cytokinin signaling pathway in Arabidopsis.","lang":"eng"}],"scopus_import":"1","date_updated":"2025-09-08T14:46:45Z","doi":"10.1016/j.molp.2024.11.001","article_type":"original","acknowledgement":"We dedicate this paper to the deceased Petr Galuszka for his inspiration and support of our project. We thank Prof. Peter Hedden for constructive criticism of the manuscript and English editing. No conflict of interest is declared.","external_id":{"isi":["001373778300001"],"pmid":["39501563"]},"date_created":"2024-11-28T11:13:35Z","_id":"18596","citation":{"ista":"Králová M, Kubalová I, Hajný J, Kubiasova K, Vagaská K, Ge Z, Gallei MC, Semerádová H, Kuchařová A, Hönig M, Monzer A, Kovačik M, Friml J, Novák O, Benková E, Ikeda Y, Zalabák D. 2024. A decoy receptor derived from alternative splicing fine-tunes cytokinin signaling in Arabidopsis. Molecular Plant. 17(12), 1850–1865.","mla":"Králová, Michaela, et al. “A Decoy Receptor Derived from Alternative Splicing Fine-Tunes Cytokinin Signaling in Arabidopsis.” <i>Molecular Plant</i>, vol. 17, no. 12, Elsevier, 2024, pp. 1850–65, doi:<a href=\"https://doi.org/10.1016/j.molp.2024.11.001\">10.1016/j.molp.2024.11.001</a>.","chicago":"Králová, Michaela, Ivona Kubalová, Jakub Hajný, Karolina Kubiasova, Karolína Vagaská, Zengxiang Ge, Michelle C Gallei, et al. “A Decoy Receptor Derived from Alternative Splicing Fine-Tunes Cytokinin Signaling in Arabidopsis.” <i>Molecular Plant</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.molp.2024.11.001\">https://doi.org/10.1016/j.molp.2024.11.001</a>.","ieee":"M. Králová <i>et al.</i>, “A decoy receptor derived from alternative splicing fine-tunes cytokinin signaling in Arabidopsis,” <i>Molecular Plant</i>, vol. 17, no. 12. Elsevier, pp. 1850–1865, 2024.","ama":"Králová M, Kubalová I, Hajný J, et al. A decoy receptor derived from alternative splicing fine-tunes cytokinin signaling in Arabidopsis. <i>Molecular Plant</i>. 2024;17(12):1850-1865. doi:<a href=\"https://doi.org/10.1016/j.molp.2024.11.001\">10.1016/j.molp.2024.11.001</a>","short":"M. Králová, I. Kubalová, J. Hajný, K. Kubiasova, K. Vagaská, Z. Ge, M.C. Gallei, H. Semerádová, A. Kuchařová, M. Hönig, A. Monzer, M. Kovačik, J. Friml, O. Novák, E. Benková, Y. Ikeda, D. Zalabák, Molecular Plant 17 (2024) 1850–1865.","apa":"Králová, M., Kubalová, I., Hajný, J., Kubiasova, K., Vagaská, K., Ge, Z., … Zalabák, D. (2024). A decoy receptor derived from alternative splicing fine-tunes cytokinin signaling in Arabidopsis. <i>Molecular Plant</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molp.2024.11.001\">https://doi.org/10.1016/j.molp.2024.11.001</a>"},"article_processing_charge":"Yes (in subscription journal)","day":"02","publication":"Molecular Plant","file":[{"content_type":"application/pdf","file_id":"18612","date_created":"2024-12-03T11:08:09Z","checksum":"a11feea4b1677df76b632eca04bfc1dd","access_level":"open_access","success":1,"file_name":"2024_MolecularPlant_Kralova.pdf","creator":"dernst","relation":"main_file","date_updated":"2024-12-03T11:08:09Z","file_size":3308945}],"publisher":"Elsevier","date_published":"2024-12-02T00:00:00Z","year":"2024","department":[{"_id":"JiFr"},{"_id":"EvBe"}],"month":"12","publication_identifier":{"issn":["1674-2052"]},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"OA_type":"hybrid","type":"journal_article"},{"status":"public","isi":1,"intvolume":"     15234","author":[{"id":"87e34708-d6c6-11ec-9f5b-9391e7be2463","last_name":"Chalupa","full_name":"Chalupa, Marek","first_name":"Marek"},{"first_name":"Thomas A","full_name":"Henzinger, Thomas A","last_name":"Henzinger","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Oliveira da Costa","orcid":"0000-0002-8741-5799","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","first_name":"Ana","full_name":"Oliveira da Costa, Ana"}],"volume":15234,"oa_version":"None","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","page":"151-171","language":[{"iso":"eng"}],"title":"Monitoring extended hypernode logic","corr_author":"1","publication_status":"published","quality_controlled":"1","doi":"10.1007/978-3-031-76554-4_9","date_created":"2024-12-01T23:01:52Z","ec_funded":1,"external_id":{"isi":["001416640500009"]},"acknowledgement":"This work was supported in part by the ERC-2020-AdG 101020093, and by the Austrian Science Fund (FWF) SFB project SpyCoDe F8502.","citation":{"apa":"Chalupa, M., Henzinger, T. A., &#38; Oliveira da Costa, A. (2024). Monitoring extended hypernode logic. In <i>Integrated Formal Methods</i> (Vol. 15234, pp. 151–171). Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-76554-4_9\">https://doi.org/10.1007/978-3-031-76554-4_9</a>","mla":"Chalupa, Marek, et al. “Monitoring Extended Hypernode Logic.” <i>Integrated Formal Methods</i>, vol. 15234, Springer Nature, 2024, pp. 151–71, doi:<a href=\"https://doi.org/10.1007/978-3-031-76554-4_9\">10.1007/978-3-031-76554-4_9</a>.","ista":"Chalupa M, Henzinger TA, Oliveira da Costa A. 2024. Monitoring extended hypernode logic. Integrated Formal Methods. , LNCS, vol. 15234, 151–171.","short":"M. Chalupa, T.A. Henzinger, A. Oliveira da Costa, in:, Integrated Formal Methods, Springer Nature, 2024, pp. 151–171.","ama":"Chalupa M, Henzinger TA, Oliveira da Costa A. Monitoring extended hypernode logic. In: <i>Integrated Formal Methods</i>. Vol 15234. Springer Nature; 2024:151-171. doi:<a href=\"https://doi.org/10.1007/978-3-031-76554-4_9\">10.1007/978-3-031-76554-4_9</a>","chicago":"Chalupa, Marek, Thomas A Henzinger, and Ana Oliveira da Costa. “Monitoring Extended Hypernode Logic.” In <i>Integrated Formal Methods</i>, 15234:151–71. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-3-031-76554-4_9\">https://doi.org/10.1007/978-3-031-76554-4_9</a>.","ieee":"M. Chalupa, T. A. Henzinger, and A. Oliveira da Costa, “Monitoring extended hypernode logic,” in <i>Integrated Formal Methods</i>, 2024, vol. 15234, pp. 151–171."},"_id":"18599","article_processing_charge":"No","abstract":[{"text":"Hypernode logic can reason about the prefix relation on stutter-reduced finite traces through the stutter-reduced prefix predicate. We increase the expressiveness of hypernode logic in two ways. First, we split the stutter-reduced prefix predicate into an explicit stutter-reduction operator and the classical prefix predicate on words. This change gives hypernode logic the ability to combine synchronous and asynchronous reasoning by explicitly stating which parts of traces can stutter. Second, we allow the use of regular expressions in formulas to reason about the structure of traces. This change enables hypernode logic to describe a mixture of trace properties and hyperproperties.\r\n\r\nWe show how to translate extended hypernode logic formulas into multi-track automata, which are automata that read multiple input words. Then we describe a fully online monitoring algorithm for monitoring k-safety hyperproperties specified in the logic. We have implemented the monitoring algorithm, and evaluated it on monitoring synchronous and asynchronous versions of observational determinism, and on checking the privacy preservation by compiler optimizations.","lang":"eng"}],"scopus_import":"1","date_updated":"2025-09-08T14:47:22Z","department":[{"_id":"ToHe"}],"month":"11","year":"2024","OA_type":"closed access","type":"conference","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783031765537"],"issn":["0302-9743"]},"day":"13","publisher":"Springer Nature","alternative_title":["LNCS"],"publication":"Integrated Formal Methods","project":[{"grant_number":"101020093","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software"},{"name":"Interface Theory for Security and Privacy","_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502"}],"date_published":"2024-11-13T00:00:00Z"},{"publication_status":"published","quality_controlled":"1","oa_version":"Preprint","volume":14550,"title":"Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report","arxiv":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","language":[{"iso":"eng"}],"page":"90-146","intvolume":"     14550","author":[{"full_name":"Andriushchenko, Roman","first_name":"Roman","last_name":"Andriushchenko"},{"last_name":"Bork","first_name":"Alexander","full_name":"Bork, Alexander"},{"last_name":"Budde","first_name":"Carlos E.","full_name":"Budde, Carlos E."},{"last_name":"Češka","first_name":"Milan","full_name":"Češka, Milan"},{"first_name":"Kush","full_name":"Grover, Kush","last_name":"Grover"},{"last_name":"Hahn","first_name":"Ernst Moritz","full_name":"Hahn, Ernst Moritz"},{"full_name":"Hartmanns, Arnd","first_name":"Arnd","last_name":"Hartmanns"},{"last_name":"Israelsen","full_name":"Israelsen, Bryant","first_name":"Bryant"},{"first_name":"Nils","full_name":"Jansen, Nils","last_name":"Jansen"},{"last_name":"Jeppson","full_name":"Jeppson, Joshua","first_name":"Joshua"},{"last_name":"Junges","first_name":"Sebastian","full_name":"Junges, Sebastian"},{"last_name":"Köhl","first_name":"Maximilian A.","full_name":"Köhl, Maximilian A."},{"first_name":"Bettina","full_name":"Könighofer, Bettina","last_name":"Könighofer"},{"full_name":"Kretinsky, Jan","first_name":"Jan","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","last_name":"Kretinsky","orcid":"0000-0002-8122-2881"},{"id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1","orcid":"0000-0002-1712-2165","last_name":"Meggendorfer","full_name":"Meggendorfer, Tobias","first_name":"Tobias"},{"full_name":"Parker, David","first_name":"David","last_name":"Parker"},{"last_name":"Pranger","first_name":"Stefan","full_name":"Pranger, Stefan"},{"full_name":"Quatmann, Tim","first_name":"Tim","last_name":"Quatmann"},{"last_name":"Ruijters","first_name":"Enno","full_name":"Ruijters, Enno"},{"first_name":"Landon","full_name":"Taylor, Landon","last_name":"Taylor"},{"last_name":"Volk","first_name":"Matthias","full_name":"Volk, Matthias"},{"first_name":"Maximilian","full_name":"Weininger, Maximilian","last_name":"Weininger","id":"02ab0197-cc70-11ed-ab61-918e71f56881"},{"first_name":"Zhen","full_name":"Zhang, Zhen","last_name":"Zhang"}],"oa":1,"isi":1,"OA_place":"repository","status":"public","day":"01","date_published":"2024-11-01T00:00:00Z","publisher":"Springer Nature","alternative_title":["LNCS"],"publication":"TOOLympics Challenge 2023","department":[{"_id":"KrCh"}],"month":"11","year":"2024","type":"conference","OA_type":"green","publication_identifier":{"issn":["0302-9743"],"isbn":["9783031676949"],"eissn":["1611-3349"]},"abstract":[{"lang":"eng","text":"The analysis of formal models that include quantitative aspects such as timing or probabilistic choices is performed by quantitative verification tools. Broad and mature tool support is available for computing basic properties such as expected rewards on basic models such as Markov chains. Previous editions of QComp, the comparison of tools for the analysis of quantitative formal models, focused on this setting. Many application scenarios, however, require more advanced property types such as LTL and parameter synthesis queries as well as advanced models like stochastic games and partially observable MDPs. For these, tool support is in its infancy today. This paper presents the outcomes of QComp 2023: a survey of the state of the art in quantitative verification tool support for advanced property types and models. With tools ranging from first research prototypes to well-supported integrations into established toolsets, this report highlights today’s active areas and tomorrow’s challenges in tool-focused research for quantitative verification."}],"date_updated":"2025-09-08T14:45:11Z","scopus_import":"1","acknowledgement":"The authors are ordered alphabetically. This work was supported by DFG RTG 2236/2 (UnRAVeL) and DFG project TRR 248 (CPEC, ID 389792660), by the EU under MSCA grant agreements 101008233 (MISSION), 101034413 (IST-BRIDGE), and 101067199 (ProSVED), by ERC Starting Grant 101077178 (DEUCE), ERC Consolidator Grant 864075 (CAESAR), and ERC Advanced Grant 834115 (FUN2MODEL), by GAČR grant GA23-06963S (VESCAA), by National Science Foundation grant 1856733, by NextGenerationEU project D53D23008400006 (SMARTITUDE), and by NWO VENI grant 639.021.754.","date_created":"2024-12-01T23:01:53Z","external_id":{"arxiv":["2405.13583"],"isi":["001434957500004"]},"doi":"10.1007/978-3-031-67695-6_4","article_processing_charge":"No","citation":{"ama":"Andriushchenko R, Bork A, Budde CE, et al. Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report. In: <i>TOOLympics Challenge 2023</i>. Vol 14550. Springer Nature; 2024:90-146. doi:<a href=\"https://doi.org/10.1007/978-3-031-67695-6_4\">10.1007/978-3-031-67695-6_4</a>","ieee":"R. Andriushchenko <i>et al.</i>, “Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report,” in <i>TOOLympics Challenge 2023</i>, 2024, vol. 14550, pp. 90–146.","chicago":"Andriushchenko, Roman, Alexander Bork, Carlos E. Budde, Milan Češka, Kush Grover, Ernst Moritz Hahn, Arnd Hartmanns, et al. “Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report.” In <i>TOOLympics Challenge 2023</i>, 14550:90–146. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-3-031-67695-6_4\">https://doi.org/10.1007/978-3-031-67695-6_4</a>.","short":"R. Andriushchenko, A. Bork, C.E. Budde, M. Češka, K. Grover, E.M. Hahn, A. Hartmanns, B. Israelsen, N. Jansen, J. Jeppson, S. Junges, M.A. Köhl, B. Könighofer, J. Kretinsky, T. Meggendorfer, D. Parker, S. Pranger, T. Quatmann, E. Ruijters, L. Taylor, M. Volk, M. Weininger, Z. Zhang, in:, TOOLympics Challenge 2023, Springer Nature, 2024, pp. 90–146.","ista":"Andriushchenko R, Bork A, Budde CE, Češka M, Grover K, Hahn EM, Hartmanns A, Israelsen B, Jansen N, Jeppson J, Junges S, Köhl MA, Könighofer B, Kretinsky J, Meggendorfer T, Parker D, Pranger S, Quatmann T, Ruijters E, Taylor L, Volk M, Weininger M, Zhang Z. 2024. Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report. TOOLympics Challenge 2023. , LNCS, vol. 14550, 90–146.","mla":"Andriushchenko, Roman, et al. “Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report.” <i>TOOLympics Challenge 2023</i>, vol. 14550, Springer Nature, 2024, pp. 90–146, doi:<a href=\"https://doi.org/10.1007/978-3-031-67695-6_4\">10.1007/978-3-031-67695-6_4</a>.","apa":"Andriushchenko, R., Bork, A., Budde, C. E., Češka, M., Grover, K., Hahn, E. M., … Zhang, Z. (2024). Tools at the Frontiers of Quantitative Verification: QComp 2023 Competition Report. In <i>TOOLympics Challenge 2023</i> (Vol. 14550, pp. 90–146). Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-67695-6_4\">https://doi.org/10.1007/978-3-031-67695-6_4</a>"},"main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2405.13583"}],"_id":"18600"},{"quality_controlled":"1","publication_status":"published","file_date_updated":"2024-12-03T11:00:15Z","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Strong hole-photon coupling in planar Ge for probing charge degree and strongly correlated states","volume":15,"DOAJ_listed":"1","oa_version":"Published Version","author":[{"last_name":"De Palma","first_name":"Franco","full_name":"De Palma, Franco"},{"last_name":"Oppliger","first_name":"Fabian","full_name":"Oppliger, Fabian"},{"first_name":"Wonjin","full_name":"Jang, Wonjin","last_name":"Jang"},{"first_name":"Stefano","full_name":"Bosco, Stefano","last_name":"Bosco"},{"first_name":"Marian","full_name":"Janik, Marian","orcid":"0009-0003-9037-8831","last_name":"Janik","id":"396A1950-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Calcaterra","first_name":"Stefano","full_name":"Calcaterra, Stefano"},{"full_name":"Katsaros, Georgios","first_name":"Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","last_name":"Katsaros","orcid":"0000-0001-8342-202X"},{"first_name":"Giovanni","full_name":"Isella, Giovanni","last_name":"Isella"},{"last_name":"Loss","first_name":"Daniel","full_name":"Loss, Daniel"},{"last_name":"Scarlino","full_name":"Scarlino, Pasquale","first_name":"Pasquale"}],"intvolume":"        15","has_accepted_license":"1","ddc":["530"],"status":"public","OA_place":"publisher","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"isi":1,"pmid":1,"oa":1,"publication":"Nature Communications","file":[{"content_type":"application/pdf","date_created":"2024-12-03T11:00:15Z","file_id":"18611","access_level":"open_access","checksum":"ef9f99a84089c388904cc8aa8d89c55a","success":1,"file_name":"2024_NatureComm_dePalma.pdf","creator":"dernst","relation":"main_file","date_updated":"2024-12-03T11:00:15Z","file_size":5288092}],"publisher":"Springer Nature","article_number":"10177","project":[{"name":"Towards scalable hut wire quantum devices","call_identifier":"FWF","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","grant_number":"P32235"},{"_id":"c0977eea-5a5b-11eb-8a69-a862db0cf4d1","name":"High impedance circuit quantum electrodynamics with hole spins","grant_number":"I05060"}],"date_published":"2024-12-01T00:00:00Z","day":"01","publication_identifier":{"eissn":["2041-1723"]},"OA_type":"gold","type":"journal_article","year":"2024","month":"12","department":[{"_id":"GeKa"}],"scopus_import":"1","date_updated":"2025-09-08T14:46:06Z","abstract":[{"text":"Semiconductor quantum dots (QDs) in planar germanium (Ge) heterostructures have emerged as front-runners for future hole-based quantum processors. Here, we present strong coupling between a hole charge qubit, defined in a double quantum dot (DQD) in planar Ge, and microwave photons in a high-impedance (Zr = 1.3 kΩ) resonator based on an array of superconducting quantum interference devices (SQUIDs). Our investigation reveals vacuum-Rabi splittings with coupling strengths up to g0/2π = 260 MHz, and a cooperativity of C ~ 100, dependent on DQD tuning. Furthermore, utilizing the frequency tunability of our resonator, we explore the quenched energy splitting associated with strong Coulomb correlation effects in Ge QDs. The observed enhanced coherence of the strongly correlated excited state signals the presence of distinct symmetries within related spin functions, serving as a precursor to the strong coupling between photons and spin-charge hybrid qubits in planar Ge. This work paves the way towards coherent quantum connections between remote hole qubits in planar Ge, required to scale up hole-based quantum processors.","lang":"eng"}],"_id":"18602","citation":{"apa":"De Palma, F., Oppliger, F., Jang, W., Bosco, S., Janik, M., Calcaterra, S., … Scarlino, P. (2024). Strong hole-photon coupling in planar Ge for probing charge degree and strongly correlated states. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-54520-7\">https://doi.org/10.1038/s41467-024-54520-7</a>","short":"F. De Palma, F. Oppliger, W. Jang, S. Bosco, M. Janik, S. Calcaterra, G. Katsaros, G. Isella, D. Loss, P. Scarlino, Nature Communications 15 (2024).","chicago":"De Palma, Franco, Fabian Oppliger, Wonjin Jang, Stefano Bosco, Marian Janik, Stefano Calcaterra, Georgios Katsaros, Giovanni Isella, Daniel Loss, and Pasquale Scarlino. “Strong Hole-Photon Coupling in Planar Ge for Probing Charge Degree and Strongly Correlated States.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-54520-7\">https://doi.org/10.1038/s41467-024-54520-7</a>.","ieee":"F. De Palma <i>et al.</i>, “Strong hole-photon coupling in planar Ge for probing charge degree and strongly correlated states,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","ama":"De Palma F, Oppliger F, Jang W, et al. Strong hole-photon coupling in planar Ge for probing charge degree and strongly correlated states. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-54520-7\">10.1038/s41467-024-54520-7</a>","ista":"De Palma F, Oppliger F, Jang W, Bosco S, Janik M, Calcaterra S, Katsaros G, Isella G, Loss D, Scarlino P. 2024. Strong hole-photon coupling in planar Ge for probing charge degree and strongly correlated states. Nature Communications. 15, 10177.","mla":"De Palma, Franco, et al. “Strong Hole-Photon Coupling in Planar Ge for Probing Charge Degree and Strongly Correlated States.” <i>Nature Communications</i>, vol. 15, 10177, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-54520-7\">10.1038/s41467-024-54520-7</a>."},"article_processing_charge":"Yes","doi":"10.1038/s41467-024-54520-7","article_type":"original","date_created":"2024-12-01T23:01:53Z","acknowledgement":"The authors thank Simone Frasca, Vincent Jouanny, Guillaume Beaulieu, Camille Roy, Dominic Dahinden, Davide Lombardo, Daniel Chrastina, and Siddhart Gautam for contributing to some cleanroom fabrication steps, the measurement setup, device simulations, data analysis, and for the useful discussions. P.S. acknowledges support from the Swiss National Science Foundation (SNSF) through the grants Ref. No. 200021 200418 and Ref. No. 206021_205335, and from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 01042765 SEFRI MB22.00081. W.J. acknowledges support from the EPFL QSE Postdoctoral Fellowship Grant. S.B., D.L., and P.S. acknowledge support from the NCCR Spin Qubit in Silicon (NCCR-SPIN) Grant No. 51NF40-180604. M.J., G.K., G.I., and S.C. acknowledge support from the Horizon Europe Project IGNITE ID 101070193. G.K. acknowledges support from the FWF via the P32235 and I05060 projects.","external_id":{"isi":["001362684200001"],"pmid":["39580488"]}},{"pmid":1,"oa":1,"ddc":["570"],"status":"public","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","isi":1,"issue":"11","intvolume":"        22","has_accepted_license":"1","APC_amount":"6248,82 EUR","author":[{"orcid":"0000-0003-2344-1039","last_name":"Kim","id":"3F8ABDDA-F248-11E8-B48F-1D18A9856A87","first_name":"Olena","full_name":"Kim, Olena"},{"id":"3337E116-F248-11E8-B48F-1D18A9856A87","last_name":"Okamoto","orcid":"0000-0003-0408-6094","full_name":"Okamoto, Yuji","first_name":"Yuji"},{"id":"3F99E422-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9735-5315","last_name":"Kaufmann","full_name":"Kaufmann, Walter","first_name":"Walter"},{"full_name":"Brose, Nils","first_name":"Nils","last_name":"Brose"},{"first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M","first_name":"Peter M"}],"volume":22,"DOAJ_listed":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","corr_author":"1","title":"Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons","publication_status":"published","file_date_updated":"2024-12-03T08:56:53Z","quality_controlled":"1","doi":"10.1371/journal.pbio.3002879","article_type":"original","date_created":"2024-12-01T23:01:54Z","ec_funded":1,"acknowledgement":"We thank Carolina Borges-Merjane, Jing-Jing Chen, Katharina Lichter, and Samuel Young for critically reading the manuscript; the Electron Microscopy Facility of ISTA, in particular Vanessa Zheden, for extensive support, advice, and experimental assistance; the Preclinical Facility of ISTA, in particular Victoria Wimmer and Michael Schunn, for experimental assistance; Florian Marr and Christina Altmutter for technical support; Alois Schlögl for help with analysis; and Eleftheria Kralli-Beller for manuscript editing. We also thank Cordelia Imig for providing Munc13-1cKO-Munc13-2/3(−/−) mutant mice. Part of the work has been published in O.K.’s thesis in partial fulfillment of the requirements for the degree of Doctor of Philosophy.\r\nThis project received funding from the European Research Council and European Union’s Horizon 2020 research and innovation programme (ERC 692692 to P.J.; https://cordis.europa.eu/project/id/692692/de) and from the Fond zur Förderung der Wissenschaftlichen Forschung (Z312-B27 Wittgenstein award to P.J., https://www.fwf.ac.at/en/funding/portfolio/projects/fwf-wittgenstein-award; W1205-B09 and P36232-B to P.J., https://www.fwf.ac.at/en/funding; I6166-B to R.S.; https://www.fwf.ac.at/en/funding). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","external_id":{"isi":["001358568700003"],"pmid":["39556620"]},"_id":"18603","citation":{"ieee":"O. Kim, Y. Okamoto, W. Kaufmann, N. Brose, R. Shigemoto, and P. M. Jonas, “Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons,” <i>PLoS Biology</i>, vol. 22, no. 11. Public Library of Science, 2024.","ama":"Kim O, Okamoto Y, Kaufmann W, Brose N, Shigemoto R, Jonas PM. Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons. <i>PLoS Biology</i>. 2024;22(11). doi:<a href=\"https://doi.org/10.1371/journal.pbio.3002879\">10.1371/journal.pbio.3002879</a>","short":"O. Kim, Y. Okamoto, W. Kaufmann, N. Brose, R. Shigemoto, P.M. Jonas, PLoS Biology 22 (2024).","chicago":"Kim, Olena, Yuji Okamoto, Walter Kaufmann, Nils Brose, Ryuichi Shigemoto, and Peter M Jonas. “Presynaptic CAMP-PKA-Mediated Potentiation Induces Reconfiguration of Synaptic Vesicle Pools and Channel-Vesicle Coupling at Hippocampal Mossy Fiber Boutons.” <i>PLoS Biology</i>. Public Library of Science, 2024. <a href=\"https://doi.org/10.1371/journal.pbio.3002879\">https://doi.org/10.1371/journal.pbio.3002879</a>.","mla":"Kim, Olena, et al. “Presynaptic CAMP-PKA-Mediated Potentiation Induces Reconfiguration of Synaptic Vesicle Pools and Channel-Vesicle Coupling at Hippocampal Mossy Fiber Boutons.” <i>PLoS Biology</i>, vol. 22, no. 11, e3002879, Public Library of Science, 2024, doi:<a href=\"https://doi.org/10.1371/journal.pbio.3002879\">10.1371/journal.pbio.3002879</a>.","ista":"Kim O, Okamoto Y, Kaufmann W, Brose N, Shigemoto R, Jonas PM. 2024. Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons. PLoS Biology. 22(11), e3002879.","apa":"Kim, O., Okamoto, Y., Kaufmann, W., Brose, N., Shigemoto, R., &#38; Jonas, P. M. (2024). Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.3002879\">https://doi.org/10.1371/journal.pbio.3002879</a>"},"article_processing_charge":"Yes","abstract":[{"lang":"eng","text":"It is widely believed that information storage in neuronal circuits involves nanoscopic structural changes at synapses, resulting in the formation of synaptic engrams. However, direct evidence for this hypothesis is lacking. To test this conjecture, we combined chemical potentiation, functional analysis by paired pre-postsynaptic recordings, and structural analysis by electron microscopy (EM) and freeze-fracture replica labeling (FRL) at the rodent hippocampal mossy fiber synapse, a key synapse in the trisynaptic circuit of the hippocampus. Biophysical analysis of synaptic transmission revealed that forskolin-induced chemical potentiation increased the readily releasable vesicle pool size and vesicular release probability by 146% and 49%, respectively. Structural analysis of mossy fiber synapses by EM and FRL demonstrated an increase in the number of vesicles close to the plasma membrane and the number of clusters of the priming protein Munc13-1, indicating an increase in the number of both docked and primed vesicles. Furthermore, FRL analysis revealed a significant reduction of the distance between Munc13-1 and CaV2.1 Ca2+ channels, suggesting reconfiguration of the channel-vesicle coupling nanotopography. Our results indicate that presynaptic plasticity is associated with structural reorganization of active zones. We propose that changes in potential nanoscopic organization at synaptic vesicle release sites may be correlates of learning and memory at a plastic central synapse."}],"scopus_import":"1","related_material":{"record":[{"id":"18296","status":"public","relation":"research_data"}]},"date_updated":"2026-04-16T12:20:34Z","year":"2024","month":"11","department":[{"_id":"PeJo"},{"_id":"EM-Fac"},{"_id":"RySh"}],"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"PreCl"}],"publication_identifier":{"issn":["1544-9173"],"eissn":["1545-7885"]},"OA_type":"gold","type":"journal_article","day":"18","publication":"PLoS Biology","publisher":"Public Library of Science","file":[{"file_name":"2024_PloSBio_Kim.pdf","relation":"main_file","creator":"dernst","file_size":3057631,"date_updated":"2024-12-03T08:56:53Z","content_type":"application/pdf","date_created":"2024-12-03T08:56:53Z","file_id":"18608","access_level":"open_access","checksum":"7de2dcb50deb65dde05c80082bb85a82","success":1}],"date_published":"2024-11-18T00:00:00Z","article_number":"e3002879","project":[{"grant_number":"692692","call_identifier":"H2020","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse"},{"name":"Synaptic communication in neuronal microcircuits","call_identifier":"FWF","_id":"25C5A090-B435-11E9-9278-68D0E5697425","grant_number":"Z00312"},{"name":"Mechanisms of GABA release in hippocampal circuits","_id":"bd88be38-d553-11ed-ba76-81d5a70a6ef5","grant_number":"P36232"},{"_id":"b1b85715-d554-11ed-a5ad-84a07fc9f18e","name":"Structural & functional basis of presynaptic plasticity","grant_number":"I06166"},{"grant_number":"W01205","name":"Zellkommunikation in Gesundheit und Krankheit","_id":"25C3DBB6-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"name":"FWF Open Access Fund","_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","call_identifier":"FWF"}]},{"language":[{"iso":"eng"}],"page":"47-82","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"title":"Removing popular faces in curve arrangements","corr_author":"1","volume":28,"DOAJ_listed":"1","oa_version":"Published Version","quality_controlled":"1","publication_status":"published","file_date_updated":"2024-12-03T09:45:00Z","status":"public","ddc":["510"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","oa":1,"author":[{"last_name":"De Nooijer","first_name":"Phoebe","full_name":"De Nooijer, Phoebe"},{"last_name":"Terziadis","full_name":"Terziadis, Soeren","first_name":"Soeren"},{"last_name":"Weinberger","first_name":"Alexandra","full_name":"Weinberger, Alexandra"},{"orcid":"0000-0002-6660-1322","last_name":"Masárová","id":"45CFE238-F248-11E8-B48F-1D18A9856A87","first_name":"Zuzana","full_name":"Masárová, Zuzana"},{"full_name":"Mchedlidze, Tamara","first_name":"Tamara","last_name":"Mchedlidze"},{"first_name":"Maarten","full_name":"Löffler, Maarten","last_name":"Löffler"},{"full_name":"Rote, Günter","first_name":"Günter","last_name":"Rote"}],"intvolume":"        28","issue":"2","has_accepted_license":"1","publication_identifier":{"issn":["1526-1719"]},"type":"journal_article","OA_type":"gold","year":"2024","department":[{"_id":"UlWa"},{"_id":"HeEd"}],"month":"11","publication":"Journal of Graph Algorithms and Applications","publisher":"Brown University","file":[{"creator":"dernst","relation":"main_file","date_updated":"2024-12-03T09:45:00Z","file_size":1582493,"file_name":"2024_JourGraphAlgorithms_deNooijer.pdf","checksum":"be611da6f9d790dc980d6fb7283fe889","access_level":"open_access","success":1,"content_type":"application/pdf","file_id":"18609","date_created":"2024-12-03T09:45:00Z"}],"date_published":"2024-11-03T00:00:00Z","day":"03","_id":"18604","citation":{"mla":"De Nooijer, Phoebe, et al. “Removing Popular Faces in Curve Arrangements.” <i>Journal of Graph Algorithms and Applications</i>, vol. 28, no. 2, Brown University, 2024, pp. 47–82, doi:<a href=\"https://doi.org/10.7155/jgaa.v28i2.2988\">10.7155/jgaa.v28i2.2988</a>.","ista":"De Nooijer P, Terziadis S, Weinberger A, Masárová Z, Mchedlidze T, Löffler M, Rote G. 2024. Removing popular faces in curve arrangements. Journal of Graph Algorithms and Applications. 28(2), 47–82.","ama":"De Nooijer P, Terziadis S, Weinberger A, et al. Removing popular faces in curve arrangements. <i>Journal of Graph Algorithms and Applications</i>. 2024;28(2):47-82. doi:<a href=\"https://doi.org/10.7155/jgaa.v28i2.2988\">10.7155/jgaa.v28i2.2988</a>","chicago":"De Nooijer, Phoebe, Soeren Terziadis, Alexandra Weinberger, Zuzana Masárová, Tamara Mchedlidze, Maarten Löffler, and Günter Rote. “Removing Popular Faces in Curve Arrangements.” <i>Journal of Graph Algorithms and Applications</i>. Brown University, 2024. <a href=\"https://doi.org/10.7155/jgaa.v28i2.2988\">https://doi.org/10.7155/jgaa.v28i2.2988</a>.","ieee":"P. De Nooijer <i>et al.</i>, “Removing popular faces in curve arrangements,” <i>Journal of Graph Algorithms and Applications</i>, vol. 28, no. 2. Brown University, pp. 47–82, 2024.","short":"P. De Nooijer, S. Terziadis, A. Weinberger, Z. Masárová, T. Mchedlidze, M. Löffler, G. Rote, Journal of Graph Algorithms and Applications 28 (2024) 47–82.","apa":"De Nooijer, P., Terziadis, S., Weinberger, A., Masárová, Z., Mchedlidze, T., Löffler, M., &#38; Rote, G. (2024). Removing popular faces in curve arrangements. <i>Journal of Graph Algorithms and Applications</i>. Brown University. <a href=\"https://doi.org/10.7155/jgaa.v28i2.2988\">https://doi.org/10.7155/jgaa.v28i2.2988</a>"},"article_processing_charge":"No","doi":"10.7155/jgaa.v28i2.2988","article_type":"original","date_created":"2024-12-01T23:01:54Z","acknowledgement":"This work was initiated at the 16th European Research Week on Geometric Graphs in Strobl in 2019. A.W. has been supported by the Austrian Science Fund (FWF): W1230. S.T. has been funded by the Vienna Science and Technology Fund (WWTF) [10.47379/ICT19035] and by the NWO Gravitation project NETWORKS under grant no. 024.002.003. Part of the work was done while A.W. was emplyed at Graz University of Technology. Preliminary versions of this work have been presented at the 38th European Workshop on Computational Geometry (EuroCG\r\n2022) in Perugia [10] and at the 31st International Symposium on Graph Drawing and Network Visualization (GD 2023) in Isola delle Femmine [11].","external_id":{"arxiv":["2202.12175"]},"scopus_import":"1","date_updated":"2024-12-03T09:49:18Z","abstract":[{"lang":"eng","text":"A face in a curve arrangement is called popular if it is bounded by the same curve multiple times. Motivated by the automatic generation of curved nonogram puzzles, we investigate possibilities to eliminate the popular faces in an arrangement by inserting a single additional curve. This turns out to be NP-hard; however, it becomes tractable when the number of popular faces is small: We present a randomized FPT-time algorithm where the parameter is the number of popular faces."}]},{"abstract":[{"lang":"eng","text":"By patterning an ultrathin layered structure with tiny wells, physicists have created and imaged peculiar states known as quantum scars — revealing behaviour that could be used to boost the performance of electronic devices."}],"scopus_import":"1","date_updated":"2025-09-08T14:57:35Z","doi":"10.1038/d41586-024-03649-y","article_type":"letter_note","external_id":{"isi":["001367935000029"],"pmid":["39604614"]},"date_created":"2024-12-03T18:08:16Z","_id":"18616","citation":{"mla":"Abanin, Dmitry, and Maksym Serbyn. “Quantum Scars Make Their Mark in Graphene.” <i>Nature</i>, vol. 635, no. 8040, Springer Nature, 2024, pp. 825–26, doi:<a href=\"https://doi.org/10.1038/d41586-024-03649-y\">10.1038/d41586-024-03649-y</a>.","ista":"Abanin D, Serbyn M. 2024. Quantum scars make their mark in graphene. Nature. 635(8040), 825–826.","chicago":"Abanin, Dmitry, and Maksym Serbyn. “Quantum Scars Make Their Mark in Graphene.” <i>Nature</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/d41586-024-03649-y\">https://doi.org/10.1038/d41586-024-03649-y</a>.","short":"D. Abanin, M. Serbyn, Nature 635 (2024) 825–826.","ama":"Abanin D, Serbyn M. Quantum scars make their mark in graphene. <i>Nature</i>. 2024;635(8040):825-826. doi:<a href=\"https://doi.org/10.1038/d41586-024-03649-y\">10.1038/d41586-024-03649-y</a>","ieee":"D. Abanin and M. Serbyn, “Quantum scars make their mark in graphene,” <i>Nature</i>, vol. 635, no. 8040. Springer Nature, pp. 825–826, 2024.","apa":"Abanin, D., &#38; Serbyn, M. (2024). Quantum scars make their mark in graphene. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/d41586-024-03649-y\">https://doi.org/10.1038/d41586-024-03649-y</a>"},"article_processing_charge":"No","day":"27","publication":"Nature","publisher":"Springer Nature","date_published":"2024-11-27T00:00:00Z","year":"2024","month":"11","department":[{"_id":"MaSe"}],"publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"type":"journal_article","OA_type":"closed access","intvolume":"       635","issue":"8040","author":[{"last_name":"Abanin","full_name":"Abanin, Dmitry","first_name":"Dmitry"},{"first_name":"Maksym","full_name":"Serbyn, Maksym","last_name":"Serbyn","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"}],"pmid":1,"status":"public","isi":1,"publication_status":"published","quality_controlled":"1","volume":635,"oa_version":"None","language":[{"iso":"eng"}],"page":"825-826","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Quantum scars make their mark in graphene"},{"month":"08","department":[{"_id":"UlWa"}],"year":"2024","type":"journal_article","OA_type":"hybrid","publication_identifier":{"issn":["0021-8693"]},"day":"01","file":[{"file_size":486969,"date_updated":"2024-12-09T13:56:26Z","relation":"main_file","creator":"dernst","file_name":"2024_JourAlgebra_Bedats.pdf","success":1,"checksum":"7b01c89128ba16d5334dfab389a03878","access_level":"open_access","file_id":"18638","date_created":"2024-12-09T13:56:26Z","content_type":"application/pdf"}],"publisher":"Elsevier","publication":"Journal of Algebra","date_published":"2024-08-01T00:00:00Z","doi":"10.1016/j.jalgebra.2024.04.013","external_id":{"arxiv":["2309.11154"],"isi":["001232775600001"]},"acknowledgement":"The author is sincerely grateful for guidance, advice and valuable feedback from Roman Lávička.","date_created":"2024-12-04T07:58:45Z","article_type":"original","citation":{"mla":"Beďatš, Daniel. “Separation of Variables for Scalar-Valued Polynomials in the Non-Stable Range.” <i>Journal of Algebra</i>, vol. 651, Elsevier, 2024, pp. 281–304, doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2024.04.013\">10.1016/j.jalgebra.2024.04.013</a>.","ista":"Beďatš D. 2024. Separation of variables for scalar-valued polynomials in the non-stable range. Journal of Algebra. 651, 281–304.","ama":"Beďatš D. Separation of variables for scalar-valued polynomials in the non-stable range. <i>Journal of Algebra</i>. 2024;651:281-304. doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2024.04.013\">10.1016/j.jalgebra.2024.04.013</a>","short":"D. Beďatš, Journal of Algebra 651 (2024) 281–304.","ieee":"D. Beďatš, “Separation of variables for scalar-valued polynomials in the non-stable range,” <i>Journal of Algebra</i>, vol. 651. Elsevier, pp. 281–304, 2024.","chicago":"Beďatš, Daniel. “Separation of Variables for Scalar-Valued Polynomials in the Non-Stable Range.” <i>Journal of Algebra</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.jalgebra.2024.04.013\">https://doi.org/10.1016/j.jalgebra.2024.04.013</a>.","apa":"Beďatš, D. (2024). Separation of variables for scalar-valued polynomials in the non-stable range. <i>Journal of Algebra</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jalgebra.2024.04.013\">https://doi.org/10.1016/j.jalgebra.2024.04.013</a>"},"_id":"18617","article_processing_charge":"Yes (via OA deal)","abstract":[{"lang":"eng","text":"Any complex-valued polynomial on (Rn)k decomposes into an algebraic combination of O(n)-invariant polynomials and harmonic polynomials. This decomposition, separation of variables, is granted to be unique if n≥2k−1. We prove that the condition n≥2k−1 is not only sufficient, but also necessary for uniqueness of the separation. Moreover, we describe the structure of non-uniqueness of the separation in the boundary cases when n=2k−2 and n=2k−3.\r\nFormally, we study the kernel of a multiplication map ϕ carrying out separation of variables. We devise a general algorithmic procedure for describing Ker ϕ in the restricted non-stable range k≤n<2k−1. In the full non-stable range n<2k−1, we give formulas for highest weights of generators of the kernel as well as formulas for its Hilbert series. Using the developed methods, we obtain a list of highest weight vectors generating Ker ϕ."}],"scopus_import":"1","date_updated":"2025-09-08T14:57:00Z","volume":651,"oa_version":"Published Version","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","page":"281-304","language":[{"iso":"eng"}],"corr_author":"1","title":"Separation of variables for scalar-valued polynomials in the non-stable range","arxiv":1,"file_date_updated":"2024-12-09T13:56:26Z","publication_status":"published","quality_controlled":"1","oa":1,"ddc":["510"],"status":"public","isi":1,"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","intvolume":"       651","has_accepted_license":"1","author":[{"first_name":"Daniel","full_name":"Beďatš, Daniel","last_name":"Beďatš","orcid":"0009-0004-1828-0044","id":"78ea3cc9-31e7-11ee-aa02-a6169bbfe1f1"}]},{"month":"11","department":[{"_id":"MaSe"}],"year":"2024","type":"journal_article","OA_type":"green","publication_identifier":{"eissn":["1079-7114"],"issn":["0031-9007"]},"day":"22","project":[{"grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"}],"article_number":"216601","date_published":"2024-11-22T00:00:00Z","publisher":"American Physical Society","publication":"Physical Review Letters","date_created":"2024-12-08T23:01:55Z","acknowledgement":"F. Q. and C. H. L. acknowledge support from the QEP2.0 Grant from the Singapore National Research Foundation (Grant No. NRF2021-QEP2-02-P09) and the Singapore MOE Tier-II Grant (Grant No. MOE-T2EP50222-0003). J.-Y. D. and Z. P. acknowledge support by the Leverhulme Trust Research Leadership Award RL-2019-015. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413. This research was supported in part by Grant No. NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP). We acknowledge the use of IBM Quantum services for this work. The views expressed are those of the authors and do not reflect the official policy or position of IBM or the IBM Quantum team.","ec_funded":1,"external_id":{"isi":["001369697800005"],"arxiv":["2403.02395"],"pmid":["39642519"]},"article_type":"original","doi":"10.1103/PhysRevLett.133.216601","article_processing_charge":"No","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2403.02395"}],"citation":{"apa":"Shen, R., Qin, F., Desaules, J.-Y. M., Papić, Z., &#38; Lee, C. H. (2024). Enhanced many-body quantum scars from the non-hermitian fock skin effect. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.133.216601\">https://doi.org/10.1103/PhysRevLett.133.216601</a>","mla":"Shen, Ruizhe, et al. “Enhanced Many-Body Quantum Scars from the Non-Hermitian Fock Skin Effect.” <i>Physical Review Letters</i>, vol. 133, no. 21, 216601, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.133.216601\">10.1103/PhysRevLett.133.216601</a>.","ista":"Shen R, Qin F, Desaules J-YM, Papić Z, Lee CH. 2024. Enhanced many-body quantum scars from the non-hermitian fock skin effect. Physical Review Letters. 133(21), 216601.","chicago":"Shen, Ruizhe, Fang Qin, Jean-Yves Marc Desaules, Zlatko Papić, and Ching Hua Lee. “Enhanced Many-Body Quantum Scars from the Non-Hermitian Fock Skin Effect.” <i>Physical Review Letters</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevLett.133.216601\">https://doi.org/10.1103/PhysRevLett.133.216601</a>.","ama":"Shen R, Qin F, Desaules J-YM, Papić Z, Lee CH. Enhanced many-body quantum scars from the non-hermitian fock skin effect. <i>Physical Review Letters</i>. 2024;133(21). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.133.216601\">10.1103/PhysRevLett.133.216601</a>","short":"R. Shen, F. Qin, J.-Y.M. Desaules, Z. Papić, C.H. Lee, Physical Review Letters 133 (2024).","ieee":"R. Shen, F. Qin, J.-Y. M. Desaules, Z. Papić, and C. H. Lee, “Enhanced many-body quantum scars from the non-hermitian fock skin effect,” <i>Physical Review Letters</i>, vol. 133, no. 21. American Physical Society, 2024."},"_id":"18627","abstract":[{"lang":"eng","text":"In contrast with extended Bloch waves, a single particle can become spatially localized due to the so-called skin effect originating from non-Hermitian pumping. Here we show that in kinetically constrained many-body systems, the skin effect can instead manifest as dynamical amplification within the Fock space, beyond the intuitively expected and previously studied particle localization and clustering. We exemplify this non-Hermitian Fock skin effect in an asymmetric version of the PXP model and show that it gives rise to ergodicity-breaking eigenstates—the non-Hermitian analogs of quantum many-body scars. A distinguishing feature of these non-Hermitian scars is their enhanced robustness against external disorders. We propose an experimental realization of the non-Hermitian scar enhancement in a tilted Bose-Hubbard optical lattice with laser-induced loss. Additionally, we implement digital simulations of such scar enhancement on the IBM quantum processor. Our results show that the Fock skin effect provides a powerful tool for creating robust nonergodic states in generic open quantum systems."}],"date_updated":"2026-06-10T07:52:52Z","related_material":{"record":[{"id":"17471","relation":"research_data","status":"public"}]},"scopus_import":"1","oa_version":"Preprint","volume":133,"title":"Enhanced many-body quantum scars from the non-hermitian fock skin effect","arxiv":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","language":[{"iso":"eng"}],"publication_status":"published","quality_controlled":"1","oa":1,"pmid":1,"isi":1,"OA_place":"repository","status":"public","issue":"21","intvolume":"       133","author":[{"last_name":"Shen","first_name":"Ruizhe","full_name":"Shen, Ruizhe"},{"full_name":"Qin, Fang","first_name":"Fang","last_name":"Qin"},{"id":"6c292945-a610-11ed-9eec-c3be1ad62a80","last_name":"Desaules","orcid":"0000-0002-3749-6375","full_name":"Desaules, Jean-Yves Marc","first_name":"Jean-Yves Marc"},{"full_name":"Papić, Zlatko","first_name":"Zlatko","last_name":"Papić"},{"last_name":"Lee","first_name":"Ching Hua","full_name":"Lee, Ching Hua"}]},{"abstract":[{"lang":"eng","text":"Arctic tidewater glaciers are retreating, serving as key indicators of global warming. This study aims to assess how subglacial hydrology affects glacier front retreat by comparing two glacier–fjord models of the Hansbreen glacier: one incorporating a detailed subglacial hydrology model and another simplifying the subglacial discharge to a single channel centered in the flow line. We first validate the subglacial hydrology model by comparing its discharge channels with observations of plume activity. Simulations conducted from April to December 2010 revealed that the glacier front position aligns more closely with the observations in the coupled model than in the simplified version. Furthermore, the mass loss due to calving and submarine melting is greater in the coupled model, with the calving mass loss reaching 6 Mt by the end of the simulation compared to 4 Mt in the simplified model. These findings highlight the critical role of subglacial hydrology in predicting glacier dynamics and emphasize the importance of detailed modeling in understanding the responses of Arctic tidewater glaciers to climate change."}],"related_material":{"record":[{"id":"18634","relation":"used_in_publication","status":"public"}]},"scopus_import":"1","date_updated":"2024-12-09T09:43:48Z","doi":"10.3390/hydrology11110193","article_type":"original","date_created":"2024-12-08T23:01:55Z","acknowledgement":"E. De Andrés is supported by Margarita-Salas Grant No. UP2021-035 under the Next Generation-EU program. This research was also funded by grant PID2020-113051RB-C31 from MCIN/AEI/10.13039/501100011033/FEDER, UE.\r\nWe gratefully acknowledge Michal Cieply and Dariusz Ignatiuk from the Faculty of Natural Sciences, University of Silesia in Katowice, Poland, for their essential contributions to the Hansbreen data collection. We also extend our sincere thanks to Waldemar Walczowski from the Institute of Oceanology, Polish Academy of Sciences, Sopot, Poland, for providing Hansbuka data. Additionally, we would like to thank two anonymous reviewers for their constructive feedback, which helped to enhance the quality and clarity of this work.","_id":"18628","citation":{"ista":"De Andrés E, Muñoz Hermosilla JM, Shahateet K, Otero J. 2024. The importance of solving Subglaciar hydrology in modeling glacier retreat: A case study of Hansbreen, Svalbard. Hydrology. 11(11), 193.","mla":"De Andrés, Eva, et al. “The Importance of Solving Subglaciar Hydrology in Modeling Glacier Retreat: A Case Study of Hansbreen, Svalbard.” <i>Hydrology</i>, vol. 11, no. 11, 193, MDPI, 2024, doi:<a href=\"https://doi.org/10.3390/hydrology11110193\">10.3390/hydrology11110193</a>.","ieee":"E. De Andrés, J. M. Muñoz Hermosilla, K. Shahateet, and J. Otero, “The importance of solving Subglaciar hydrology in modeling glacier retreat: A case study of Hansbreen, Svalbard,” <i>Hydrology</i>, vol. 11, no. 11. MDPI, 2024.","ama":"De Andrés E, Muñoz Hermosilla JM, Shahateet K, Otero J. The importance of solving Subglaciar hydrology in modeling glacier retreat: A case study of Hansbreen, Svalbard. <i>Hydrology</i>. 2024;11(11). doi:<a href=\"https://doi.org/10.3390/hydrology11110193\">10.3390/hydrology11110193</a>","short":"E. De Andrés, J.M. Muñoz Hermosilla, K. Shahateet, J. Otero, Hydrology 11 (2024).","chicago":"De Andrés, Eva, José M Muñoz Hermosilla, Kaian Shahateet, and Jaime Otero. “The Importance of Solving Subglaciar Hydrology in Modeling Glacier Retreat: A Case Study of Hansbreen, Svalbard.” <i>Hydrology</i>. MDPI, 2024. <a href=\"https://doi.org/10.3390/hydrology11110193\">https://doi.org/10.3390/hydrology11110193</a>.","apa":"De Andrés, E., Muñoz Hermosilla, J. M., Shahateet, K., &#38; Otero, J. (2024). The importance of solving Subglaciar hydrology in modeling glacier retreat: A case study of Hansbreen, Svalbard. <i>Hydrology</i>. MDPI. <a href=\"https://doi.org/10.3390/hydrology11110193\">https://doi.org/10.3390/hydrology11110193</a>"},"article_processing_charge":"Yes","day":"12","publication":"Hydrology","publisher":"MDPI","file":[{"file_name":"2024_Hydrology_deAndres.pdf","date_updated":"2024-12-09T09:43:33Z","file_size":5709093,"relation":"main_file","creator":"dernst","file_id":"18635","date_created":"2024-12-09T09:43:33Z","content_type":"application/pdf","success":1,"checksum":"0665c5bfca97782bf0b041f23dd7e8d7","access_level":"open_access"}],"date_published":"2024-11-12T00:00:00Z","article_number":"193","year":"2024","month":"11","department":[{"_id":"FrPe"}],"publication_identifier":{"eissn":["2306-5338"]},"OA_type":"gold","type":"journal_article","issue":"11","intvolume":"        11","has_accepted_license":"1","author":[{"last_name":"De Andrés","full_name":"De Andrés, Eva","first_name":"Eva"},{"last_name":"Muñoz Hermosilla","id":"e1037a6d-646e-11ef-b402-e0ed9ab0901e","first_name":"José M","full_name":"Muñoz Hermosilla, José M"},{"last_name":"Shahateet","first_name":"Kaian","full_name":"Shahateet, Kaian"},{"last_name":"Otero","first_name":"Jaime","full_name":"Otero, Jaime"}],"oa":1,"status":"public","ddc":["550"],"OA_place":"publisher","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_status":"published","file_date_updated":"2024-12-09T09:43:33Z","quality_controlled":"1","volume":11,"DOAJ_listed":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","title":"The importance of solving Subglaciar hydrology in modeling glacier retreat: A case study of Hansbreen, Svalbard"},{"status":"public","OA_place":"repository","isi":1,"oa":1,"author":[{"full_name":"Shukla, Neelam","first_name":"Neelam","last_name":"Shukla"},{"first_name":"Artem","full_name":"Volosniev, Artem","last_name":"Volosniev","orcid":"0000-0003-0393-5525","id":"37D278BC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jeremy R.","full_name":"Armstrong, Jeremy R.","last_name":"Armstrong"}],"issue":"5","intvolume":"       110","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","arxiv":1,"title":"Anisotropic potential immersed in a dipolar Bose-Einstein condensate","volume":110,"oa_version":"Preprint","quality_controlled":"1","publication_status":"published","_id":"18629","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2406.00217","open_access":"1"}],"citation":{"apa":"Shukla, N., Volosniev, A., &#38; Armstrong, J. R. (2024). Anisotropic potential immersed in a dipolar Bose-Einstein condensate. <i>Physical Review A</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.110.053317\">https://doi.org/10.1103/PhysRevA.110.053317</a>","mla":"Shukla, Neelam, et al. “Anisotropic Potential Immersed in a Dipolar Bose-Einstein Condensate.” <i>Physical Review A</i>, vol. 110, no. 5, 053317, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevA.110.053317\">10.1103/PhysRevA.110.053317</a>.","ista":"Shukla N, Volosniev A, Armstrong JR. 2024. Anisotropic potential immersed in a dipolar Bose-Einstein condensate. Physical Review A. 110(5), 053317.","ama":"Shukla N, Volosniev A, Armstrong JR. Anisotropic potential immersed in a dipolar Bose-Einstein condensate. <i>Physical Review A</i>. 2024;110(5). doi:<a href=\"https://doi.org/10.1103/PhysRevA.110.053317\">10.1103/PhysRevA.110.053317</a>","ieee":"N. Shukla, A. Volosniev, and J. R. Armstrong, “Anisotropic potential immersed in a dipolar Bose-Einstein condensate,” <i>Physical Review A</i>, vol. 110, no. 5. American Physical Society, 2024.","short":"N. Shukla, A. Volosniev, J.R. Armstrong, Physical Review A 110 (2024).","chicago":"Shukla, Neelam, Artem Volosniev, and Jeremy R. Armstrong. “Anisotropic Potential Immersed in a Dipolar Bose-Einstein Condensate.” <i>Physical Review A</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevA.110.053317\">https://doi.org/10.1103/PhysRevA.110.053317</a>."},"article_processing_charge":"No","doi":"10.1103/PhysRevA.110.053317","article_type":"original","acknowledgement":"The authors acknowledge that this material is based upon work supported by the National Science Foundation/EPSCoR RII Track-1: Emergent Quantum Materials and Technologies (EQUATE), Award No. OIA-2044049.","external_id":{"isi":["001362623400019"],"arxiv":["2406.00217"]},"date_created":"2024-12-08T23:01:55Z","scopus_import":"1","date_updated":"2025-09-08T14:56:22Z","abstract":[{"lang":"eng","text":"We study a three-dimensional Gross-Pitaevskii equation that describes a static impurity in a dipolar Bose-Einstein condensate. Our focus is on the interplay between the shape of the impurity and the anisotropy of the medium manifested in the energy and the density of the system. Without external confinement, properties of the system are derived with basic analytical approaches. For a system in a harmonic trap, the model is investigated numerically, using the split-step Crank-Nicolson method. Our results demonstrate that the impurity self-energy is minimized when its shape more closely aligns with the anisotropic character of the bath; in particular a prolate deformed impurity aligned with the direction of the dipoles has the smallest self-energy for a repulsive impurity. Our work complements studies of impurities in Bose gases with zero-range interactions and paves the way for studies of dipolar polarons with a Gross-Pitaevskii equation."}],"publication_identifier":{"issn":["2469-9926"],"eissn":["2469-9934"]},"type":"journal_article","OA_type":"green","year":"2024","department":[{"_id":"MiLe"}],"month":"11","publication":"Physical Review A","publisher":"American Physical Society","date_published":"2024-11-18T00:00:00Z","article_number":"053317","day":"18"},{"publication":"Logical Methods in Computer Science","alternative_title":["LMCS"],"file":[{"file_id":"18633","date_created":"2024-12-09T08:38:48Z","content_type":"application/pdf","success":1,"checksum":"b3315c74ce18ce0a30ed33d8c9972992","access_level":"open_access","file_name":"2024_LMCS_Chatterjee.pdf","file_size":416814,"date_updated":"2024-12-09T08:38:48Z","creator":"dernst","relation":"main_file"}],"publisher":"EPI Sciences","date_published":"2024-11-12T00:00:00Z","project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","grant_number":"863818"}],"day":"12","publication_identifier":{"eissn":["1860-5974"]},"type":"journal_article","OA_type":"gold","year":"2024","department":[{"_id":"KrCh"}],"month":"11","scopus_import":"1","related_material":{"record":[{"relation":"earlier_version","status":"public","id":"10004"}]},"date_updated":"2025-09-08T14:54:14Z","abstract":[{"lang":"eng","text":"Markov chains are the de facto finite-state model for stochastic dynamical systems, and Markov decision processes (MDPs) extend Markov chains by incorporating non-deterministic behaviors. Given an MDP and rewards on states, a classical optimization criterion is the maximal expected total reward where the MDP stops after T steps, which can be computed by a simple dynamic programming algorithm. We consider a natural generalization of the problem where the stopping times can be chosen according to a probability distribution, such that the expected stopping time is T, to optimize the expected total reward. Quite surprisingly we establish inter-reducibility of the expected stopping-time problem for Markov chains with the Positivity problem (which is related to the well-known Skolem problem), for which establishing either decidability or undecidability would be a major breakthrough. Given the hardness of the exact problem, we consider the approximate version of the problem: we show that it can be solved in exponential time for Markov chains and in exponential space for MDPs."}],"_id":"18630","citation":{"ista":"Chatterjee K, Doyen L. 2024. Stochastic processes with expected stopping time. Logical Methods in Computer Science. 20(4), 11:1-11:34.","mla":"Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected Stopping Time.” <i>Logical Methods in Computer Science</i>, vol. 20, no. 4, EPI Sciences, 2024, p. 11:1-11:34, doi:<a href=\"https://doi.org/10.46298/lmcs-20(4:11)2024\">10.46298/lmcs-20(4:11)2024</a>.","ieee":"K. Chatterjee and L. Doyen, “Stochastic processes with expected stopping time,” <i>Logical Methods in Computer Science</i>, vol. 20, no. 4. EPI Sciences, p. 11:1-11:34, 2024.","short":"K. Chatterjee, L. Doyen, Logical Methods in Computer Science 20 (2024) 11:1-11:34.","ama":"Chatterjee K, Doyen L. Stochastic processes with expected stopping time. <i>Logical Methods in Computer Science</i>. 2024;20(4):11:1-11:34. doi:<a href=\"https://doi.org/10.46298/lmcs-20(4:11)2024\">10.46298/lmcs-20(4:11)2024</a>","chicago":"Chatterjee, Krishnendu, and Laurent Doyen. “Stochastic Processes with Expected Stopping Time.” <i>Logical Methods in Computer Science</i>. EPI Sciences, 2024. <a href=\"https://doi.org/10.46298/lmcs-20(4:11)2024\">https://doi.org/10.46298/lmcs-20(4:11)2024</a>.","apa":"Chatterjee, K., &#38; Doyen, L. (2024). Stochastic processes with expected stopping time. <i>Logical Methods in Computer Science</i>. EPI Sciences. <a href=\"https://doi.org/10.46298/lmcs-20(4:11)2024\">https://doi.org/10.46298/lmcs-20(4:11)2024</a>"},"article_processing_charge":"Yes","doi":"10.46298/lmcs-20(4:11)2024","article_type":"original","external_id":{"arxiv":["2104.07278"],"isi":["001367316400002"]},"ec_funded":1,"date_created":"2024-12-08T23:01:56Z","acknowledgement":"The authors are grateful to the anonymous reviewers of LICS 2021 and of a previous version of this paper for insightful comments that helped improving the presentation. The research presented in this paper was partially supported by the grant ERC CoG 863818 (ForM-SMArt).","quality_controlled":"1","publication_status":"published","file_date_updated":"2024-12-09T08:38:48Z","language":[{"iso":"eng"}],"page":"11:1-11:34","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","arxiv":1,"corr_author":"1","title":"Stochastic processes with expected stopping time","volume":20,"DOAJ_listed":"1","oa_version":"Published Version","author":[{"full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","orcid":"0000-0002-4561-241X"},{"first_name":"Laurent","full_name":"Doyen, Laurent","last_name":"Doyen"}],"intvolume":"        20","issue":"4","has_accepted_license":"1","status":"public","ddc":["000"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"OA_place":"publisher","isi":1,"oa":1}]