[{"issue":"4","oa":1,"file_date_updated":"2026-05-07T08:27:43Z","status":"public","publication_status":"published","project":[{"grant_number":"M03100","_id":"fc35eaa2-9c52-11eb-aca3-88501ab155e9","name":"Spectra and topology of graphs and of simplicial complexes"}],"day":"01","department":[{"_id":"UlWa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1112/jlms.70540","oa_version":"Published Version","OA_type":"hybrid","abstract":[{"text":"We prove that every 𝐿-bilipschitz mapping ℤ 2 → ℝ2 canbe extended to a 𝐶(𝐿)-bilipschitz mapping ℝ2 → ℝ2,and we provide a polynomial upper bound for 𝐶(𝐿).Moreover, we extend the result to every separated netin ℝ2 instead of ℤ 2, with the upper bound gaininga polynomial dependence on the separation and netconstants associated to the given separated net. Thisanswers an Oberwolfach question of Navas from 2015and is also a positive solution of the two-dimensionalform of a decades old open (in all dimensions at leasttwo) problem due to Alestalo Trotsenko and Väisälä.","lang":"eng"}],"article_number":"e70540","article_type":"original","date_created":"2026-05-03T22:01:37Z","volume":113,"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"arxiv":["2410.22294"]},"scopus_import":"1","intvolume":"       113","acknowledgement":"The authors wish to thank Professor Leonid Kovalev for a valuable observation on the first versionof this work, which led to improved estimates and cleaner proofs in Section 6. The present workdeveloped from a research visit of Michael Dymond to Vojtěch Kaluža at IST Austria, funded by aLondon Mathematical Society Research in Pairs grant. This work was done whilst Vojtěch Kalužawas fully funded by the Austria Science Fund (FWF) [M 3100-N].","OA_place":"publisher","year":"2026","citation":{"chicago":"Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from Separated Nets.” <i>Journal of the London Mathematical Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1112/jlms.70540\">https://doi.org/10.1112/jlms.70540</a>.","ama":"Dymond M, Kaluza V. Planar bilipschitz extension from separated nets. <i>Journal of the London Mathematical Society</i>. 2026;113(4). doi:<a href=\"https://doi.org/10.1112/jlms.70540\">10.1112/jlms.70540</a>","mla":"Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from Separated Nets.” <i>Journal of the London Mathematical Society</i>, vol. 113, no. 4, e70540, Wiley, 2026, doi:<a href=\"https://doi.org/10.1112/jlms.70540\">10.1112/jlms.70540</a>.","ieee":"M. Dymond and V. Kaluza, “Planar bilipschitz extension from separated nets,” <i>Journal of the London Mathematical Society</i>, vol. 113, no. 4. Wiley, 2026.","short":"M. Dymond, V. Kaluza, Journal of the London Mathematical Society 113 (2026).","apa":"Dymond, M., &#38; Kaluza, V. (2026). Planar bilipschitz extension from separated nets. <i>Journal of the London Mathematical Society</i>. Wiley. <a href=\"https://doi.org/10.1112/jlms.70540\">https://doi.org/10.1112/jlms.70540</a>","ista":"Dymond M, Kaluza V. 2026. Planar bilipschitz extension from separated nets. Journal of the London Mathematical Society. 113(4), e70540."},"_id":"21778","date_updated":"2026-05-07T08:29:18Z","month":"04","language":[{"iso":"eng"}],"publisher":"Wiley","file":[{"access_level":"open_access","date_updated":"2026-05-07T08:27:43Z","success":1,"content_type":"application/pdf","relation":"main_file","file_id":"21836","creator":"dernst","file_name":"2026_JourLondonMathSoc_Dymond.pdf","checksum":"6dbfc7134f732d17c5c8467843a73e90","file_size":617569,"date_created":"2026-05-07T08:27:43Z"}],"author":[{"full_name":"Dymond, Michael","last_name":"Dymond","first_name":"Michael"},{"orcid":"0000-0002-2512-8698","full_name":"Kaluza, Vojtech","first_name":"Vojtech","id":"21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E","last_name":"Kaluza"}],"title":"Planar bilipschitz extension from separated nets","arxiv":1,"has_accepted_license":"1","type":"journal_article","date_published":"2026-04-01T00:00:00Z","ddc":["510"],"publication":"Journal of the London Mathematical Society","quality_controlled":"1","publication_identifier":{"eissn":["1469-7750"],"issn":["0024-6107"]},"article_processing_charge":"Yes (in subscription journal)"},{"OA_place":"publisher","acknowledgement":"This work is a collaborative effort of the titled authors as part of the Origin of Life Early Career Network (OoLEN). We chose to add OoLEN as the first author to give a better representation of this team effort, rather than listing any single author as the first author. We hope such a thing can be adopted by others. We indicate that authors 2–9 (S.A., C.B., C. Blanco, D.B., A.C.-R., C.M., O.M., Z.P., and A.V.D.) have made a more distinct contribution. All authors are listed alphabetically by their last names. We would like to acknowledge all current and past members of OoLEN for their contributions to our community. In particular, we would like to acknowledge Evrim Fer, who helped with molecular phylogenetics. We would like to thank the anonymous referees for reviewing Parts 1 and 2 of this manuscript; this work was significantly improved through their feedback. S.A. acknowledges support from NASA through the postdoctoral Program at GSFC. C. Bautista acknowledges support from “la Caixa” Foundation (ID 100010434) under agreement (LCF/BQ/AA16/11580051) and by the Fonds de recherche du Québec Nature et technologies (FRQNT) (#274987). C. Blanco acknowledges support from NASA under award 80NSSC21K0595. D.B. acknowledges support from Centre national d'études spatiales (CNES) and postdoctoral support from LGPM-CentralSupélec and NASA under award 80NSSC23K1477. E. Camprubi acknowledges support from UT System for a STARs award. A.C.-R. acknowledges funding from the Natural Sciences and Engineering Research Council of Canada (grant number RGPIN/05278–2018), the Fonds de recherche Nature et Technologies of Québec (grant number 314488), and the Fondation J. Armand Bombardier Excellence Scholarship. A.C.-R.’s research was supported by an appointment to the NASA Postdoctoral Program from the NASA Astrobiology Program administered by Oak Ridge Associated Universities under contract with NASA. S.F.J. acknowledges support from “la Caixa” Foundation (ID 100010434) and from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska Curie grant agreement no. 847648 (the fellowship code is LCF/BQ/PI21/11830015). T.Z.J. acknowledges support from Japan Society for the Promotion of Science (JSPS) grants-in-aid 18K14354 and 21K14746, a Tokyo Institute of Technology Yoshinori Ohsumi Fund for Fundamental Research, the Mizuho Foundation for the Promotion of Sciences, and by the Temporary Assistant Program by the DE&I Section of Science Tokyo. A.K. acknowledges support from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant agreement no. 101068029. C.M. acknowledges support from NASA through the postdoctoral Fellowship Program. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of NASA. O.M. acknowledges support from The John Templeton Foundation (#62828) and the Foundation for Science and Technology (2023.05971.CEECIND). B.K.D.P. acknowledges support from the NSERC Banting Postdoctoral Fellowship. K.P. acknowledges financial support from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy EXC 2181/1 - 390900948 (the Heidelberg STRUCTURES Excellence Cluster) and is a fellow of the International Max Planck Research School for Astronomy and Cosmic Physics at the University of Heidelberg (IMPRS-HD).","year":"2026","language":[{"iso":"eng"}],"publisher":"Elsevier","_id":"21754","citation":{"ista":"Asche S, Bautista C, Blanco C, Boulesteix D, Champagne-Ruel A, Mathis C, Markovitch O, Peng Z, Dass AV, Adams A, Camprubi E, Colizzi ES, Colón-Santos S, Dromiack H, Erastova V, Garcia A, Grimaud G, Halpern A, Harrison SA, Jordan SF, Jia TZ, Kahana A, Kolchinsky A, Moron-Garcia O, Mizuuchi R, Nan J, Orlova Y, Pearce BKD, Paschek K, Preiner M, Pinna S, Rodríguez-Román E, Schwander L, Sharma S, Smith HB, Vieira A, Xavier JC. 2026. What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories. Cell Reports Physical Science. 7(4), 103212.","short":"S. Asche, C. Bautista, C. Blanco, D. Boulesteix, A. Champagne-Ruel, C. Mathis, O. Markovitch, Z. Peng, A.V. Dass, A. Adams, E. Camprubi, E.S. Colizzi, S. Colón-Santos, H. Dromiack, V. Erastova, A. Garcia, G. Grimaud, A. Halpern, S.A. Harrison, S.F. Jordan, T.Z. Jia, A. Kahana, A. Kolchinsky, O. Moron-Garcia, R. Mizuuchi, J. Nan, Y. Orlova, B.K.D. Pearce, K. Paschek, M. Preiner, S. Pinna, E. Rodríguez-Román, L. Schwander, S. Sharma, H.B. Smith, A. Vieira, J.C. Xavier, Cell Reports Physical Science 7 (2026).","apa":"Asche, S., Bautista, C., Blanco, C., Boulesteix, D., Champagne-Ruel, A., Mathis, C., … Xavier, J. C. (2026). What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories. <i>Cell Reports Physical Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xcrp.2026.103212\">https://doi.org/10.1016/j.xcrp.2026.103212</a>","ieee":"S. Asche <i>et al.</i>, “What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories,” <i>Cell Reports Physical Science</i>, vol. 7, no. 4. Elsevier, 2026.","ama":"Asche S, Bautista C, Blanco C, et al. What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories. <i>Cell Reports Physical Science</i>. 2026;7(4). doi:<a href=\"https://doi.org/10.1016/j.xcrp.2026.103212\">10.1016/j.xcrp.2026.103212</a>","mla":"Asche, Silke, et al. “What It Takes to Solve the Origin of Life: An Integrated Review. Part 1–Experimental Methods and Data Repositories.” <i>Cell Reports Physical Science</i>, vol. 7, no. 4, 103212, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.xcrp.2026.103212\">10.1016/j.xcrp.2026.103212</a>.","chicago":"Asche, Silke, Carla Bautista, Celia Blanco, David Boulesteix, Alexandre Champagne-Ruel, Cole Mathis, Omer Markovitch, et al. “What It Takes to Solve the Origin of Life: An Integrated Review. Part 1–Experimental Methods and Data Repositories.” <i>Cell Reports Physical Science</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.xcrp.2026.103212\">https://doi.org/10.1016/j.xcrp.2026.103212</a>."},"date_updated":"2026-05-07T12:13:25Z","month":"04","file":[{"content_type":"application/pdf","relation":"main_file","date_updated":"2026-05-07T05:48:23Z","access_level":"open_access","success":1,"file_name":"2026_CellREports_OoLEN1.pdf","date_created":"2026-05-07T05:48:23Z","checksum":"e580d22c2874c0afcbde2d167db7201b","file_size":3535247,"file_id":"21831","creator":"dernst"}],"author":[{"last_name":"Asche","first_name":"Silke","full_name":"Asche, Silke"},{"first_name":"Carla","last_name":"Bautista","full_name":"Bautista, Carla"},{"full_name":"Blanco, Celia","last_name":"Blanco","first_name":"Celia"},{"full_name":"Boulesteix, David","last_name":"Boulesteix","first_name":"David"},{"full_name":"Champagne-Ruel, Alexandre","first_name":"Alexandre","last_name":"Champagne-Ruel"},{"last_name":"Mathis","first_name":"Cole","full_name":"Mathis, Cole"},{"full_name":"Markovitch, Omer","last_name":"Markovitch","first_name":"Omer"},{"first_name":"Zhen","last_name":"Peng","full_name":"Peng, Zhen"},{"full_name":"Dass, Avinash Vicholous","first_name":"Avinash Vicholous","last_name":"Dass"},{"full_name":"Adams, Alyssa","last_name":"Adams","first_name":"Alyssa"},{"first_name":"Eloi","last_name":"Camprubi","full_name":"Camprubi, Eloi"},{"last_name":"Colizzi","first_name":"Enrico Sandro","full_name":"Colizzi, Enrico Sandro"},{"last_name":"Colón-Santos","first_name":"Stephanie","full_name":"Colón-Santos, Stephanie"},{"first_name":"Hannah","last_name":"Dromiack","full_name":"Dromiack, Hannah"},{"full_name":"Erastova, Valentina","last_name":"Erastova","first_name":"Valentina"},{"full_name":"Garcia, Amanda","first_name":"Amanda","last_name":"Garcia"},{"full_name":"Grimaud, Ghjuvan","last_name":"Grimaud","first_name":"Ghjuvan"},{"last_name":"Halpern","first_name":"Aaron","full_name":"Halpern, Aaron"},{"full_name":"Harrison, Stuart A.","first_name":"Stuart A.","last_name":"Harrison"},{"first_name":"Seán F.","last_name":"Jordan","full_name":"Jordan, Seán F."},{"full_name":"Jia, Tony Z.","last_name":"Jia","first_name":"Tony Z."},{"first_name":"Amit","last_name":"Kahana","full_name":"Kahana, Amit"},{"full_name":"Kolchinsky, Artemy","first_name":"Artemy","last_name":"Kolchinsky"},{"full_name":"Moron-Garcia, Odin","last_name":"Moron-Garcia","first_name":"Odin"},{"last_name":"Mizuuchi","first_name":"Ryo","full_name":"Mizuuchi, Ryo"},{"full_name":"Nan, Jingbo","last_name":"Nan","first_name":"Jingbo"},{"full_name":"Orlova, Yuliia","last_name":"Orlova","first_name":"Yuliia"},{"full_name":"Pearce, Ben K.D.","first_name":"Ben K.D.","last_name":"Pearce"},{"full_name":"Paschek, Klaus","last_name":"Paschek","first_name":"Klaus"},{"full_name":"Preiner, Martina","last_name":"Preiner","first_name":"Martina"},{"full_name":"Pinna, Silvana","first_name":"Silvana","last_name":"Pinna"},{"full_name":"Rodríguez-Román, Eduardo","last_name":"Rodríguez-Román","first_name":"Eduardo"},{"last_name":"Schwander","first_name":"Loraine","full_name":"Schwander, Loraine"},{"id":"36996868-4916-11f1-8c9d-c0c901467b61","first_name":"Siddhant","last_name":"Sharma","full_name":"Sharma, Siddhant"},{"first_name":"Harrison B.","last_name":"Smith","full_name":"Smith, Harrison B."},{"last_name":"Vieira","first_name":"Andrey","full_name":"Vieira, Andrey"},{"full_name":"Xavier, Joana C.","last_name":"Xavier","first_name":"Joana C."}],"title":"What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories","DOAJ_listed":"1","date_published":"2026-04-15T00:00:00Z","type":"journal_article","has_accepted_license":"1","publication":"Cell Reports Physical Science","ddc":["570"],"article_processing_charge":"Yes","quality_controlled":"1","publication_identifier":{"eissn":["2666-3864"]},"issue":"4","oa":1,"file_date_updated":"2026-05-07T05:48:23Z","publication_status":"published","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1016/j.xcrp.2026.103212","day":"15","OA_type":"gold","oa_version":"Published Version","article_type":"original","volume":7,"date_created":"2026-04-19T22:07:52Z","abstract":[{"lang":"eng","text":"The origin(s) of life (OoL), which has puzzled scientists for centuries, remains a major scientific challenge in the 21st century. Research on OoL spans many disciplines, including chemistry, physics, biology, planetary sciences, computer science, and mathematics. The sheer number of different scientific perspectives relevant to the problem has resulted in the coexistence of diverse tools, techniques, data, and software in OoL studies. This has made communication between the disciplines relevant to the OoL extremely difficult because the interpretation of data, analyses, or standards of evidence varies dramatically. Here, we hope to bridge this wide field of study by providing common ground via the consolidation of techniques rather than positing a unifying view on how life emerges. In part 1 of this review, we cover common experimental techniques that have been used significantly in OoL studies in recent years, while in part 2, we review theoretical, computational, and integrative methods. Here, we discuss the use of spectroscopy, spectrometry, chromatography, microscopy, and sequencing methods for characterizing diverse materials. We further discuss the role of data repositories in facilitating the analysis and dissemination of experimental data. This review provides a baseline expectation and understanding of the analytical aspects of origins’ research. Ultimately, we aim to provide an educational tool that can facilitate more post-disciplinary collaborations in OoL research by helping scientists understand what they can do about the problem of life’s origins, rather than telling them how to think about it."}],"article_number":"103212","scopus_import":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"intvolume":"         7"},{"article_type":"original","volume":1002,"date_created":"2026-05-10T22:02:15Z","abstract":[{"text":"We compile a sample of 83 little red dots (LRDs) with JWST imaging and find that a substantial fraction (∼43%, rising to ≳80% for the most luminous LRDs) host one or more spatially offset, UV-bright companions at projected separations of 0.5 kpc ≲ d ≲ 5 kpc, with median 〈d〉 = 1.0 kpc. This fraction is even higher when smaller spatial scales are probed at high signal-to-noise ratio: the two most strongly lensed LRDs, A383-LRD1 and the newly discovered A68-LRD1, both have UV-bright companions at separations of only d ∼ 0.3 kpc, below the resolution limit of most unlensed JWST samples. We explore whether these ubiquitous red/blue configurations may be physically linked to the formation of LRDs, in analogy with the “synchronized pair” scenario originally proposed for direct-collapse black hole formation. In this picture, UV radiation from the companions, with typically modest stellar masses (M∗ ∼ 108−109 M⊙), suppresses molecular hydrogen cooling in nearby gas, allowing nearly isothermal collapse and the formation of extremely compact objects, such as massive black holes, supermassive stars, or quasi-stars. Using component-resolved photometry and spectral energy distribution modeling, we infer Lyman–Werner radiation fields of J21,LW ∼ 102.5–105 at the locations of the red components, comparable to those required in direct-collapse models, suggesting that the necessary photodissociation conditions are realized in many LRD systems. This framework provides a simple and self-consistent explanation for the extreme compactness and distinctive spectral properties of LRDs and links long-standing theoretical models for early compact object formation directly to a population now observed with JWST in the early Universe.","lang":"eng"}],"article_number":"L4","OA_type":"gold","oa_version":"Published Version","intvolume":"      1002","scopus_import":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"arxiv":["2602.02702"]},"oa":1,"file_date_updated":"2026-05-11T06:44:37Z","PlanS_conform":"1","issue":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"ZoHa"},{"_id":"JoMa"}],"doi":"10.3847/2041-8213/ae58a5","day":"10","project":[{"name":"Young galaxies as tracers and agents of cosmic reionization","_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224"}],"publication_status":"published","status":"public","DOAJ_listed":"1","date_published":"2026-04-10T00:00:00Z","has_accepted_license":"1","type":"journal_article","arxiv":1,"author":[{"last_name":"Baggen","first_name":"Josephine F.W.","full_name":"Baggen, Josephine F.W."},{"last_name":"Scoggins","first_name":"Matthew T.","full_name":"Scoggins, Matthew T."},{"full_name":"Van Dokkum, Pieter","last_name":"Van Dokkum","first_name":"Pieter"},{"orcid":"0000-0003-3633-5403","last_name":"Haiman","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","full_name":"Haiman, Zoltán"},{"orcid":"0000-0001-5586-6950","full_name":"Torralba Torregrosa, Alberto","id":"018f0249-0e87-11f0-b167-cbce08fbd541","first_name":"Alberto","last_name":"Torralba Torregrosa"},{"last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X"}],"title":"Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation","article_processing_charge":"Yes","quality_controlled":"1","publication_identifier":{"eissn":["2041-8213"],"issn":["2041-8205"]},"publication":"The Astrophysical Journal Letters","ddc":["520"],"year":"2026","acknowledgement":"We thank Earl Bellinger, Fabio Pacucci, Andrea Ferrara, and Dale Kocevski for useful discussions. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These imaging observations are associated with programs 1345, 1180, 1181, 1243, 6882, 2561, 1324, 4111, and 1895. The compiled dataset can be accessed at doi:10.17909/1m8f-9c47. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. J.M. and A.T. acknowledge funding by the European Union (ERC, AGENTS, 101076224). This work was performed in part at Aspen Center for Physics, which is supported by National Science Foundation grant PHY-2210452. This work used the following Python packages: Matplotlib (J. D. Hunter 2007), SciPy (P. Virtanen et al. 2020), NumPy (S. van der Walt et al. 2011), AstroPy (Astropy Collaboration et al. 2022), colossus (B. Diemer 2018), and photutils (L. Bradley et al. 2025).","OA_place":"publisher","file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","date_updated":"2026-05-11T06:44:37Z","success":1,"file_name":"2026_AstrophysicalJourLetters_Baggen.pdf","file_size":13359642,"checksum":"8c31d8603cd6ad39c772a72d136dc3f8","date_created":"2026-05-11T06:44:37Z","file_id":"21851","creator":"dernst"}],"language":[{"iso":"eng"}],"publisher":"IOP Publishing","citation":{"short":"J.F.W. Baggen, M.T. Scoggins, P. Van Dokkum, Z. Haiman, A. Torralba Torregrosa, J.J. Matthee, The Astrophysical Journal Letters 1002 (2026).","apa":"Baggen, J. F. W., Scoggins, M. T., Van Dokkum, P., Haiman, Z., Torralba Torregrosa, A., &#38; Matthee, J. J. (2026). Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae58a5\">https://doi.org/10.3847/2041-8213/ae58a5</a>","ista":"Baggen JFW, Scoggins MT, Van Dokkum P, Haiman Z, Torralba Torregrosa A, Matthee JJ. 2026. Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation. The Astrophysical Journal Letters. 1002(1), L4.","mla":"Baggen, Josephine F. W., et al. “Connecting the Dots: UV-Bright Companions of Little Red Dots as Lyman–Werner Sources Enabling Direct-Collapse Black Hole Formation.” <i>The Astrophysical Journal Letters</i>, vol. 1002, no. 1, L4, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae58a5\">10.3847/2041-8213/ae58a5</a>.","ama":"Baggen JFW, Scoggins MT, Van Dokkum P, Haiman Z, Torralba Torregrosa A, Matthee JJ. Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation. <i>The Astrophysical Journal Letters</i>. 2026;1002(1). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae58a5\">10.3847/2041-8213/ae58a5</a>","ieee":"J. F. W. Baggen, M. T. Scoggins, P. Van Dokkum, Z. Haiman, A. Torralba Torregrosa, and J. J. Matthee, “Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation,” <i>The Astrophysical Journal Letters</i>, vol. 1002, no. 1. IOP Publishing, 2026.","chicago":"Baggen, Josephine F.W., Matthew T. Scoggins, Pieter Van Dokkum, Zoltán Haiman, Alberto Torralba Torregrosa, and Jorryt J Matthee. “Connecting the Dots: UV-Bright Companions of Little Red Dots as Lyman–Werner Sources Enabling Direct-Collapse Black Hole Formation.” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/2041-8213/ae58a5\">https://doi.org/10.3847/2041-8213/ae58a5</a>."},"_id":"21846","date_updated":"2026-05-11T06:48:33Z","month":"04"},{"date_published":"2026-04-29T00:00:00Z","DOAJ_listed":"1","type":"journal_article","has_accepted_license":"1","arxiv":1,"title":"Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2","author":[{"orcid":"0000-0002-8806-5719","full_name":"Zambra, Valeska","id":"467ed36b-dc96-11ea-b7c8-b043a380b282","first_name":"Valeska","last_name":"Zambra"},{"last_name":"Nathwani","first_name":"Amit","id":"1a362536-4d02-11f1-8543-8351136efc50","full_name":"Nathwani, Amit"},{"last_name":"Nauman","first_name":"Muhammad","id":"32c21954-2022-11eb-9d5f-af9f93c24e71","full_name":"Nauman, Muhammad","orcid":"0000-0002-2111-4846"},{"last_name":"Lewin","first_name":"Sylvia K.","full_name":"Lewin, Sylvia K."},{"full_name":"Frank, Corey E.","first_name":"Corey E.","last_name":"Frank"},{"full_name":"Butch, Nicholas P.","first_name":"Nicholas P.","last_name":"Butch"},{"full_name":"Shekhter, Arkady","last_name":"Shekhter","first_name":"Arkady"},{"last_name":"Ramshaw","first_name":"B. J.","full_name":"Ramshaw, B. J."},{"full_name":"Modic, Kimberly A","first_name":"Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","last_name":"Modic","orcid":"0000-0001-9760-3147"}],"article_processing_charge":"Yes","publication_identifier":{"eissn":["2041-1723"]},"quality_controlled":"1","publication":"Nature Communications","ddc":["530"],"year":"2026","OA_place":"publisher","acknowledgement":"We appreciate technical support from Salvatore Bagiante, Evgeniia Volobueva, Lubuna Shafeek, Ali Bangura, and Zoltán Köllö, and scientific discussions with Daniel Agterberg, Johnpierre Paglione, Qimiao Si, Josephine Yu and Yue Yu. V.Z., A.N., M.N., and K.A.M. acknowledge funding received from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (TROPIC-101078696). V.Z., A.N., M.N., and K.A.M. thank the ISTA Nanofabrication Facility for technical support. B.J.R. acknowledges funding from the Office of Basic Energy Sciences of the United States Department of Energy under award number DE-SC0020143 for data analysis and writing. The National High Magnetic Field Laboratory is supported by the National Science Foundation through NSF/DMR-2128556*, the State of Florida, and the U.S. Department of Energy. A.S. acknowledges support from the DOE/BES “Science of 100 T” grant. A.S. thanks Downtown Subscription in Santa Fe, NM, for their patience in hosting him. Sample preparation and characterization were supported by the NSF through DMR-2105191.","file":[{"file_name":"2026_NatureComm_Zambra.pdf","checksum":"8cb95b033ad2a1a7a8181f6f078c05b5","file_size":1784917,"date_created":"2026-05-11T06:32:12Z","file_id":"21850","creator":"dernst","content_type":"application/pdf","relation":"main_file","date_updated":"2026-05-11T06:32:12Z","access_level":"open_access","success":1}],"corr_author":"1","publisher":"Springer Nature","language":[{"iso":"eng"}],"month":"04","date_updated":"2026-05-11T06:36:00Z","_id":"21845","citation":{"ista":"Zambra V, Nathwani A, Nauman M, Lewin SK, Frank CE, Butch NP, Shekhter A, Ramshaw BJ, Modic KA. 2026. Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2. Nature Communications. 17, 3742.","short":"V. Zambra, A. Nathwani, M. Nauman, S.K. Lewin, C.E. Frank, N.P. Butch, A. Shekhter, B.J. Ramshaw, K.A. Modic, Nature Communications 17 (2026).","apa":"Zambra, V., Nathwani, A., Nauman, M., Lewin, S. K., Frank, C. E., Butch, N. P., … Modic, K. A. (2026). Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-71899-7\">https://doi.org/10.1038/s41467-026-71899-7</a>","ieee":"V. Zambra <i>et al.</i>, “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ama":"Zambra V, Nathwani A, Nauman M, et al. Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-71899-7\">10.1038/s41467-026-71899-7</a>","mla":"Zambra, Valeska, et al. “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.” <i>Nature Communications</i>, vol. 17, 3742, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-71899-7\">10.1038/s41467-026-71899-7</a>.","chicago":"Zambra, Valeska, Amit Nathwani, Muhammad Nauman, Sylvia K. Lewin, Corey E. Frank, Nicholas P. Butch, Arkady Shekhter, B. J. Ramshaw, and Kimberly A Modic. “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-71899-7\">https://doi.org/10.1038/s41467-026-71899-7</a>."},"date_created":"2026-05-10T22:02:15Z","volume":17,"article_type":"original","related_material":{"record":[{"id":"21174","relation":"research_data","status":"public"}]},"article_number":"3742","abstract":[{"lang":"eng","text":"UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby the zero-resistance state reappears above 40 tesla after being suppressed with a field of around 10 tesla. One potential pairing mechanism, invoked in the related re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of a ferromagnetic order parameter. However, the requisite ferromagnetic order—present in both UCoGe and URhGe—is absent in UTe2, and neutron scattering shows instead that the magnetic susceptibility is peaked at an antiferromagnetic wavevector. Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle planes. This quantity is sensitive to the magnetic susceptibility in a direction transverse to the applied magnetic field—a quantity that is not accessed in conventional magnetization measurements. We observe a very large decrease in the magnetotropic susceptibility over a broad range of field orientations, indicating a large increase in the transverse magnetic susceptibility. Because our technique probes the magnetic susceptibility in the long wavelength (q = 0) limit, this suggests that the strong transverse susceptibility arises from ferromagnetic spin fluctuations. These ferromagnetic fluctuations are likely important for understanding the pairing mechanism in UTe2, as all three superconducting phases of UTe2 surround this region of enhanced susceptibility in the field-angle phase diagram."}],"OA_type":"gold","oa_version":"Published Version","intvolume":"        17","scopus_import":"1","external_id":{"arxiv":["2506.08984"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"file_date_updated":"2026-05-11T06:32:12Z","PlanS_conform":"1","acknowledged_ssus":[{"_id":"NanoFab"}],"doi":"10.1038/s41467-026-71899-7","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"KiMo"},{"_id":"GradSch"}],"day":"29","project":[{"name":"Gaining leverage with spin liquids and superconductors","_id":"bd968c70-d553-11ed-ba76-cde40b0aba64","grant_number":"101078696"}],"publication_status":"published","status":"public"},{"file":[{"file_id":"21852","creator":"dernst","file_name":"2026_PhysicalReviewResearch_Moller.pdf","file_size":1829628,"checksum":"dbfc58e1e176f7b63e0d274eb0d1bffa","date_created":"2026-05-11T06:56:58Z","access_level":"open_access","date_updated":"2026-05-11T06:56:58Z","success":1,"content_type":"application/pdf","relation":"main_file"}],"language":[{"iso":"eng"}],"publisher":"American Physical Society","_id":"21847","citation":{"chicago":"Moller, Frederik Skovbo, Gabriel Fernández-Fernández, Thomas Schweigler, Paulin De Schoulepnikoff, Jörg Schmiedmayer, and Gorka Muñoz-Gil. “Learning Minimal Representations of Many-Body Physics from Snapshots of a Quantum Simulator.” <i>Physical Review Research</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/r7pj-gl7r\">https://doi.org/10.1103/r7pj-gl7r</a>.","short":"F.S. Moller, G. Fernández-Fernández, T. Schweigler, P. De Schoulepnikoff, J. Schmiedmayer, G. Muñoz-Gil, Physical Review Research 8 (2026).","apa":"Moller, F. S., Fernández-Fernández, G., Schweigler, T., De Schoulepnikoff, P., Schmiedmayer, J., &#38; Muñoz-Gil, G. (2026). Learning minimal representations of many-body physics from snapshots of a quantum simulator. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/r7pj-gl7r\">https://doi.org/10.1103/r7pj-gl7r</a>","ista":"Moller FS, Fernández-Fernández G, Schweigler T, De Schoulepnikoff P, Schmiedmayer J, Muñoz-Gil G. 2026. Learning minimal representations of many-body physics from snapshots of a quantum simulator. Physical Review Research. 8(2), 023094.","ama":"Moller FS, Fernández-Fernández G, Schweigler T, De Schoulepnikoff P, Schmiedmayer J, Muñoz-Gil G. Learning minimal representations of many-body physics from snapshots of a quantum simulator. <i>Physical Review Research</i>. 2026;8(2). doi:<a href=\"https://doi.org/10.1103/r7pj-gl7r\">10.1103/r7pj-gl7r</a>","mla":"Moller, Frederik Skovbo, et al. “Learning Minimal Representations of Many-Body Physics from Snapshots of a Quantum Simulator.” <i>Physical Review Research</i>, vol. 8, no. 2, 023094, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/r7pj-gl7r\">10.1103/r7pj-gl7r</a>.","ieee":"F. S. Moller, G. Fernández-Fernández, T. Schweigler, P. De Schoulepnikoff, J. Schmiedmayer, and G. Muñoz-Gil, “Learning minimal representations of many-body physics from snapshots of a quantum simulator,” <i>Physical Review Research</i>, vol. 8, no. 2. American Physical Society, 2026."},"date_updated":"2026-05-11T06:58:56Z","month":"04","year":"2026","OA_place":"publisher","acknowledgement":"We thank Sebastian Erne and Igor Mazets for helpful discussions and sharing codes for the transfer matrix sampling. This research was funded in part by the European Research Council: ERC Advanced Grant “Emergence in Quantum Physics” (EmQ) under Grant Agreement No. 101097858 and ERC Advanced Grant “Artificial agency and learning in quantum environments” (QuantAI) under Grant Agreement No. 101055129. This work was also supported by the Austrian Science Fund (FWF) (SFB BeyondC F7102, 10.55776/F71). G.F.-F. acknowledges the European Research Council AdG NOQIA; MCIN/AEI [PGC2018-0910.13039/501100011033, CEX2019-000910-S/10.13039/501100011033, Plan National FIDEUA PID2019-106901GB-I00, Plan National STAMEENA PID2022-139099NB, I00, project funded by MCIN/AEI/10.13039/501100011033 and by the “European Union NextGenerationEU/PRTR” (PRTR-C17.I1), FPI]; QUANTERA DYNAMITE PCI2022-132919 under Grant Agreement No. 101017733; Ministry for Digital Transformation and of Civil Service of the Spanish Government through the QUANTUM ENIA project call—Quantum Spain project, and by the European Union through the Recovery, Transformation and Resilience Plan—NextGenerationEU within the framework of the Digital Spain 2026 Agenda; Fundació Cellex; Fundació Mir-Puig; Generalitat de Catalunya (European Social Fund FEDER and CERCA program); Barcelona Supercomputing Center MareNostrum (FI-2023-3-0024); (HORIZON-CL4-2022-QUANTUM-02-SGA PASQuanS2.1, 101113690, EU Horizon 2020 FET-OPEN OPTOlogic, Grant No. 899794, QU-ATTO, 101168628), EU Horizon Europe Program (This project has received funding from the European Union's Horizon Europe research and innovation program under Grant Agreement No. 101080086 NeQST); ICFO Internal “QuantumGaudi” project. This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/COE1] through the Cluster of Excellence quantA (Quantum Science Austria).\r\n\r\nThe views and opinions expressed in this article are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council—neither the European Union nor the granting authority can be held responsible for them.","article_processing_charge":"Yes","quality_controlled":"1","publication_identifier":{"eissn":["2643-1564"]},"publication":"Physical Review Research","ddc":["530"],"DOAJ_listed":"1","date_published":"2026-04-29T00:00:00Z","type":"journal_article","has_accepted_license":"1","arxiv":1,"author":[{"first_name":"Frederik Skovbo","id":"43cbcc83-0564-11f0-a935-e37325525859","last_name":"Moller","full_name":"Moller, Frederik Skovbo"},{"full_name":"Fernández-Fernández, Gabriel","first_name":"Gabriel","last_name":"Fernández-Fernández"},{"full_name":"Schweigler, Thomas","last_name":"Schweigler","first_name":"Thomas"},{"last_name":"De Schoulepnikoff","first_name":"Paulin","full_name":"De Schoulepnikoff, Paulin"},{"full_name":"Schmiedmayer, Jörg","last_name":"Schmiedmayer","first_name":"Jörg"},{"full_name":"Muñoz-Gil, Gorka","last_name":"Muñoz-Gil","first_name":"Gorka"}],"title":"Learning minimal representations of many-body physics from snapshots of a quantum simulator","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"EdHa"}],"doi":"10.1103/r7pj-gl7r","day":"29","publication_status":"published","status":"public","file_date_updated":"2026-05-11T06:56:58Z","oa":1,"PlanS_conform":"1","issue":"2","intvolume":"         8","scopus_import":"1","external_id":{"arxiv":["2509.13821"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","volume":8,"date_created":"2026-05-10T22:02:15Z","abstract":[{"text":"Analog quantum simulators provide access to many-body dynamics beyond the reach of classical computation. However, extracting physical insights from experimental data is often hindered by measurement noise, limited observables, and incomplete knowledge of the underlying microscopic model. Here, we develop a machine learning approach based on a variational autoencoder (VAE) to analyze interference measurements of tunnel-coupled one-dimensional Bose gases, which realize the sine-Gordon quantum field theory. Trained in an unsupervised manner, the VAE learns a minimal latent representation that strongly correlates with the equilibrium control parameter of the system. Applied to nonequilibrium protocols, the latent space uncovers signatures of frozen-in solitons following rapid cooling, and reveals anomalous postquench dynamics not captured by conventional correlation-based methods. These results demonstrate that generative models can extract physically interpretable variables directly from noisy and sparse experimental data, providing complementary probes of equilibrium and nonequilibrium physics in quantum simulators. More broadly, our work highlights how machine learning can supplement established field-theoretical techniques, paving the way for scalable, data-driven discovery in quantum many-body systems.","lang":"eng"}],"article_number":"023094","OA_type":"gold","oa_version":"Published Version"},{"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"OA_type":"free access","oa_version":"Published Version","date_created":"2026-02-09T12:04:20Z","abstract":[{"lang":"eng","text":"UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby the zero-resistance state reappears above 40 tesla after being suppressed with a field of around 10 tesla. One potential pairing mechanism, invoked in the related re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of a ferromagnetic order parameter. However, the requisite ferromagnetic order - present in both UCoGe and URhGe - is absent in UTe2, and magnetization measurements show no sign of strong fluctuations. Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle planes. This quantity is sensitive to the magnetic susceptibility in a direction transverse to the applied magnetic field - a quantity that is not accessed in conventional magnetization measurements. We observe a very large decrease in the magnetotropic susceptibility over a broad range of field orientations, indicating a large increase in the transverse magnetic susceptibility. The three superconducting phases of UTe2, including the high-field re-entrant phase, surround this region of enhanced susceptibility in the field-angle phase diagram. The strongest transverse susceptibility is found near the critical end point of the high-field metamagnetic transition, suggesting that quantum critical fluctuations of a field-induced magnetic order parameter may be responsible for the large transverse susceptibility, and may provide a pairing mechanism for field-induced superconductivity in UTe2."}],"related_material":{"link":[{"url":"https://arxiv.org/pdf/2506.08984","relation":"preprint"}],"record":[{"status":"public","relation":"used_in_publication","id":"21845"}]},"status":"public","department":[{"_id":"KiMo"}],"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","doi":"10.15479/AT-ISTA-21174","acknowledged_ssus":[{"_id":"NanoFab"}],"day":"19","project":[{"name":"Gaining leverage with spin liquids and superconductors","grant_number":"101078696","_id":"bd968c70-d553-11ed-ba76-cde40b0aba64"}],"keyword":["transverse magnetic susceptibility","magnetotropic","superconductivity","magnetic fluctuations"],"file_date_updated":"2026-02-19T07:39:07Z","oa":1,"ddc":["530"],"article_processing_charge":"Yes","author":[{"full_name":"Modic, Kimberly A","last_name":"Modic","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","first_name":"Kimberly A","orcid":"0000-0001-9760-3147"}],"title":"Research data for \"Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2\"","date_published":"2026-02-19T00:00:00Z","type":"research_data","has_accepted_license":"1","corr_author":"1","publisher":"Institute of Science and Technology Austria","_id":"21174","citation":{"chicago":"Modic, Kimberly A. “Research Data for ‘Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">https://doi.org/10.15479/AT-ISTA-21174</a>.","ieee":"K. A. Modic, “Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026.","mla":"Modic, Kimberly A. <i>Research Data for “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>.","ama":"Modic KA. Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>","ista":"Modic KA. 2026. Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>.","short":"K.A. Modic, (2026).","apa":"Modic, K. A. (2026). Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">https://doi.org/10.15479/AT-ISTA-21174</a>"},"date_updated":"2026-05-11T06:35:59Z","month":"02","file":[{"content_type":"text/plain","relation":"main_file","date_updated":"2026-02-19T07:38:15Z","access_level":"open_access","success":1,"file_name":"README.txt","file_size":1347,"checksum":"53157d908fba663275c2b8dc6ee84fdb","date_created":"2026-02-19T07:38:15Z","file_id":"21332","creator":"kmodic"},{"file_name":"processed_data_bc_plane_Fig2d.zip","file_size":534853,"checksum":"b2c8ca5620ee9c181a42082068d3d73c","date_created":"2026-02-19T07:39:03Z","file_id":"21333","creator":"kmodic","content_type":"application/zip","relation":"main_file","date_updated":"2026-02-19T07:39:03Z","access_level":"open_access","success":1},{"file_id":"21334","creator":"kmodic","file_name":"processed_data_ac_plane_Fig2c.zip","checksum":"976bf113da4b1133313f0b292e71289f","file_size":427144,"date_created":"2026-02-19T07:39:07Z","access_level":"open_access","date_updated":"2026-02-19T07:39:07Z","success":1,"content_type":"application/zip","relation":"main_file"}],"contributor":[{"contributor_type":"project_member","id":"467ed36b-dc96-11ea-b7c8-b043a380b282","first_name":"Valeska","last_name":"Zambra","orcid":"0000-0002-8806-5719"}],"OA_place":"repository","acknowledgement":"Thanks to Salvatore Bagiante, Evgeniia Volobueva, Lubuna Shafeek, Ali Bangura and Zoltan Kollo.","year":"2026"},{"month":"04","_id":"21849","date_updated":"2026-05-11T06:22:47Z","citation":{"chicago":"Olmeda, Fabrizio, Tim Lohoff, Ioannis Kafetzopoulos, Stephen J. Clark, Laura Benson, Fatima Santos, Felix Krueger, Simon Walker, Wolf Reik, and Steffen Rulands. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>.","ieee":"F. Olmeda <i>et al.</i>, “Scaling and self-similarity in the formation of the embryonic epigenome,” <i>Nature Physics</i>. Springer Nature, 2026.","mla":"Olmeda, Fabrizio, et al. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>.","ama":"Olmeda F, Lohoff T, Kafetzopoulos I, et al. Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>","ista":"Olmeda F, Lohoff T, Kafetzopoulos I, Clark SJ, Benson L, Santos F, Krueger F, Walker S, Reik W, Rulands S. 2026. Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics.","apa":"Olmeda, F., Lohoff, T., Kafetzopoulos, I., Clark, S. J., Benson, L., Santos, F., … Rulands, S. (2026). Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>","short":"F. Olmeda, T. Lohoff, I. Kafetzopoulos, S.J. Clark, L. Benson, F. Santos, F. Krueger, S. Walker, W. Reik, S. Rulands, Nature Physics (2026)."},"publisher":"Springer Nature","language":[{"iso":"eng"}],"acknowledgement":"We thank all members of the W.R. and S.R. laboratories, F. Piazza, B. D. Simons, and F. Jülicher for helpful discussions. We thank M. Ciarchi for providing annotations for the chromatin compartments. S.R. is a member of the Center for Nano Science (CeNS). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement number 950349). Research in W.R.’s laboratory was supported by the Biotechnology and Biological Sciences Research Council (BB/K010867/1), Wellcome (095645/Z/11/Z) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (EpiCell lineage 882798). F.O. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. Open access funding provided by Max Planck Society.","OA_place":"publisher","year":"2026","ddc":["570"],"publication":"Nature Physics","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","title":"Scaling and self-similarity in the formation of the embryonic epigenome","author":[{"full_name":"Olmeda, Fabrizio","last_name":"Olmeda","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","first_name":"Fabrizio"},{"full_name":"Lohoff, Tim","first_name":"Tim","last_name":"Lohoff"},{"full_name":"Kafetzopoulos, Ioannis","first_name":"Ioannis","last_name":"Kafetzopoulos"},{"full_name":"Clark, Stephen J.","last_name":"Clark","first_name":"Stephen J."},{"full_name":"Benson, Laura","first_name":"Laura","last_name":"Benson"},{"first_name":"Fatima","last_name":"Santos","full_name":"Santos, Fatima"},{"full_name":"Krueger, Felix","first_name":"Felix","last_name":"Krueger"},{"full_name":"Walker, Simon","first_name":"Simon","last_name":"Walker"},{"full_name":"Reik, Wolf","first_name":"Wolf","last_name":"Reik"},{"full_name":"Rulands, Steffen","last_name":"Rulands","first_name":"Steffen"}],"ec_funded":1,"has_accepted_license":"1","type":"journal_article","date_published":"2026-04-29T00:00:00Z","status":"public","publication_status":"epub_ahead","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"day":"29","doi":"10.1038/s41567-026-03263-x","department":[{"_id":"EdHa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","PlanS_conform":"1","oa":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41567-026-03263-x","open_access":"1"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"scopus_import":"1","oa_version":"Published Version","OA_type":"hybrid","abstract":[{"lang":"eng","text":"The development of complex tissues relies on the precise assignment of cell identity. At the molecular scale, this process depends on the deposition of epigenetic modifications—such as methylation—that are regulated by complex biochemical networks and occur at specific regions on the DNA and chromatin. Here we show that despite the complexity of epigenetic regulation, dynamical scaling and self-similarity of DNA methylation marks emerge in embryonic development. Drawing on single-cell multi-omics experiments, super-resolution microscopy and statistical physics, we demonstrate that these phenomena originate in dynamical feedback between DNA methylation and the formation of nanoscale dynamic chromatin aggregates. These nanoscale processes lead to genome-wide increase in DNA methylation marks following a power law and self-similar correlation functions. Using this framework, we identify methylation patterns that precede gene expression changes in embryonic symmetry breaking. Our work identifies linear sequencing measurements as a laboratory to study mesoscopic biophysical processes in vivo."}],"date_created":"2026-05-10T22:02:16Z","article_type":"original"},{"_id":"21848","date_updated":"2026-05-11T06:07:32Z","citation":{"chicago":"Klein, Klara, Litty Johnson, Ramona Rîca, Mirza Sarcevic, Gabriele Carta, Saskia Seiser, Adelheid Elbe-Bürger, et al. “Langerhans Cell–Targeted MRNA Delivery: A Strategy for Dose-Sparing and Enhanced Antitumor Immunity.” <i>Journal of Investigative Dermatology</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.jid.2026.03.026\">https://doi.org/10.1016/j.jid.2026.03.026</a>.","apa":"Klein, K., Johnson, L., Rîca, R., Sarcevic, M., Carta, G., Seiser, S., … Sparber, F. (n.d.). Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor immunity. <i>Journal of Investigative Dermatology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jid.2026.03.026\">https://doi.org/10.1016/j.jid.2026.03.026</a>","short":"K. Klein, L. Johnson, R. Rîca, M. Sarcevic, G. Carta, S. Seiser, A. Elbe-Bürger, F. Langer, N. Rahhal, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Journal of Investigative Dermatology (n.d.).","ista":"Klein K, Johnson L, Rîca R, Sarcevic M, Carta G, Seiser S, Elbe-Bürger A, Langer F, Rahhal N, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor immunity. Journal of Investigative Dermatology.","mla":"Klein, Klara, et al. “Langerhans Cell–Targeted MRNA Delivery: A Strategy for Dose-Sparing and Enhanced Antitumor Immunity.” <i>Journal of Investigative Dermatology</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.jid.2026.03.026\">10.1016/j.jid.2026.03.026</a>.","ama":"Klein K, Johnson L, Rîca R, et al. Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor immunity. <i>Journal of Investigative Dermatology</i>. doi:<a href=\"https://doi.org/10.1016/j.jid.2026.03.026\">10.1016/j.jid.2026.03.026</a>","ieee":"K. Klein <i>et al.</i>, “Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor immunity,” <i>Journal of Investigative Dermatology</i>. Elsevier."},"month":"04","language":[{"iso":"eng"}],"publisher":"Elsevier","year":"2026","OA_place":"repository","acknowledgement":"We thank Mareike Rentzsch for her intellectual contributions during the course of our discussions. We thank Michael Schunn from the Preclinical Facility of the Institute of Science and Technology Austria for his continuous technical support. Guarantor of the work is FS. This project was supported by “Seedfinancing” (P2282679) of the Austrian Federal Ministry of Digital and Economic Affairs and the Ministry of Climate Action and Energy, handled by the Austrian Wirtschaftsservice, as well as by...","publication_identifier":{"issn":["0022-202X"],"eissn":["1523-1747"]},"article_processing_charge":"No","publication":"Journal of Investigative Dermatology","type":"journal_article","date_published":"2026-04-07T00:00:00Z","author":[{"full_name":"Klein, Klara","first_name":"Klara","last_name":"Klein"},{"first_name":"Litty","last_name":"Johnson","full_name":"Johnson, Litty"},{"full_name":"Rîca, Ramona","last_name":"Rîca","first_name":"Ramona"},{"first_name":"Mirza","last_name":"Sarcevic","full_name":"Sarcevic, Mirza"},{"full_name":"Carta, Gabriele","last_name":"Carta","first_name":"Gabriele"},{"last_name":"Seiser","first_name":"Saskia","full_name":"Seiser, Saskia"},{"first_name":"Adelheid","last_name":"Elbe-Bürger","full_name":"Elbe-Bürger, Adelheid"},{"full_name":"Langer, Freyja","first_name":"Freyja","id":"3C1BE782-F248-11E8-B48F-1D18A9856A87","last_name":"Langer"},{"first_name":"Nowras","last_name":"Rahhal","full_name":"Rahhal, Nowras"},{"first_name":"Christoph","last_name":"Rademacher","full_name":"Rademacher, Christoph"},{"full_name":"Wawrzinek, Robert","last_name":"Wawrzinek","first_name":"Robert"},{"last_name":"Quattrone","first_name":"Federica","full_name":"Quattrone, Federica"},{"last_name":"Sparber","first_name":"Florian","full_name":"Sparber, Florian"}],"title":"Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor immunity","day":"07","department":[{"_id":"PreCl"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledged_ssus":[{"_id":"PreCl"}],"doi":"10.1016/j.jid.2026.03.026","status":"public","publication_status":"inpress","main_file_link":[{"url":"https://doi.org/10.1101/2025.06.25.661517","open_access":"1"}],"oa":1,"scopus_import":"1","abstract":[{"text":"Despite the success of mRNA therapeutics, challenges remain in optimizing immune responses and minimizing side effects. Cell-specific antigen delivery may help reduce required doses and improve vaccine efficacy. In this study, we report on a targeted delivery system for mRNA to a specific subset of skin-resident antigen-presenting cells: Langerhans cells. By functionalizing lipid nanoparticles with a langerin-specific glycomimetic ligand, we achieve selective mRNA delivery to both murine and human primary Langerhans cells with minimal off-target uptake, at the same time resulting in significantly increased mRNA translation. This targeted mRNA delivery not only enhances antigen presentation and T-cell responses but also enables dose-sparing and superior antitumor immunity compared with conventional immunization in a B16-OVA tumor model. Importantly, our platform’s high compatibility with various lipid nanoparticle formulations offers a flexible and precise tool for skin-directed mRNA delivery.","lang":"eng"}],"article_type":"original","date_created":"2026-05-10T22:02:16Z","oa_version":"Preprint","OA_type":"green"},{"publication_status":"published","status":"public","doi":"10.3847/1538-4357/ae548d","department":[{"_id":"ZoHa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","PlanS_conform":"1","issue":"1","file_date_updated":"2026-05-11T07:07:22Z","oa":1,"scopus_import":"1","external_id":{"arxiv":["2505.05322"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"intvolume":"      1002","OA_type":"gold","oa_version":"Published Version","date_created":"2026-05-10T22:02:14Z","volume":1002,"article_type":"original","article_number":"25","abstract":[{"lang":"eng","text":"Little red dots (LRDs) are a newly identified class of broad-line active galactic nuclei (AGNs) with a distinctive V-shaped spectrum characterized by red optical and blue UV continuum emission. Their high abundance at redshifts of z ∼ 6–8 and decline at lower redshifts suggest a transient origin. We propose that the spectral shape of LRDs originates from compact binary black hole systems, in which each black hole is surrounded by a mini-disk and embedded within a larger circumbinary disk. With a binary separation of ≲103 Schwarzschild radii, the Wien tail of a T ≃ 5000 K blackbody spectrum at the inner edge of the circumbinary disk produces the red optical emission, while the mini-disks power the UV continuum. Binary torques carve out a gap between the circumbinary disk and the mini-disks, setting the turnover wavelength of the V-shaped spectrum around the Balmer limit. This scenario naturally reproduces LRD spectra requiring only modest dust attenuation (AV ≲ 1 mag), resolving overestimated luminosities for LRDs in previous studies and alleviating a tension with the so-called Sołtan argument. This model predicts distinct spectral evolution as the binary orbit decays through binary disk interactions and gravitational-wave (GW) emission, linking early-stage “proto-LRD” binaries to the broader AGN population and late-stage “LRD descendants” to coalescing binaries detectable in GW experiments."}],"publisher":"IOP Publishing","language":[{"iso":"eng"}],"month":"05","_id":"21844","date_updated":"2026-05-11T07:09:12Z","citation":{"short":"K. Inayoshi, J. Shangguan, X. Chen, L.C. Ho, Z. Haiman, The Astrophysical Journal 1002 (2026).","apa":"Inayoshi, K., Shangguan, J., Chen, X., Ho, L. C., &#38; Haiman, Z. (2026). The emergence of Little Red Dots from binary massive black holes. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae548d\">https://doi.org/10.3847/1538-4357/ae548d</a>","ista":"Inayoshi K, Shangguan J, Chen X, Ho LC, Haiman Z. 2026. The emergence of Little Red Dots from binary massive black holes. The Astrophysical Journal. 1002(1), 25.","mla":"Inayoshi, Kohei, et al. “The Emergence of Little Red Dots from Binary Massive Black Holes.” <i>The Astrophysical Journal</i>, vol. 1002, no. 1, 25, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae548d\">10.3847/1538-4357/ae548d</a>.","ama":"Inayoshi K, Shangguan J, Chen X, Ho LC, Haiman Z. The emergence of Little Red Dots from binary massive black holes. <i>The Astrophysical Journal</i>. 2026;1002(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae548d\">10.3847/1538-4357/ae548d</a>","ieee":"K. Inayoshi, J. Shangguan, X. Chen, L. C. Ho, and Z. Haiman, “The emergence of Little Red Dots from binary massive black holes,” <i>The Astrophysical Journal</i>, vol. 1002, no. 1. IOP Publishing, 2026.","chicago":"Inayoshi, Kohei, Jinyi Shangguan, Xian Chen, Luis C. Ho, and Zoltán Haiman. “The Emergence of Little Red Dots from Binary Massive Black Holes.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae548d\">https://doi.org/10.3847/1538-4357/ae548d</a>."},"file":[{"date_created":"2026-05-11T07:07:22Z","checksum":"b4506dfef3dd6da335775071d8f2a0a6","file_size":3041897,"file_name":"2026_AstrophysicalJour_Inayoshi.pdf","creator":"dernst","file_id":"21853","relation":"main_file","content_type":"application/pdf","success":1,"date_updated":"2026-05-11T07:07:22Z","access_level":"open_access"}],"acknowledgement":"We greatly thank Kenta Hotokezaka and Hanpu Liu for constructive discussions. K.I., J.S., X.C., and L.C.H. acknowledge support from National Natural Science Foundation of China (grant Nos. 12573015, 1251101148, 12233001, and 12473037), the Beijing Natural Science Foundation (grant No. IS25003), and the China Manned Space Program (grant No. CMS-CSST-2025-A09). J.S. is also supported by “The Fundamental Research Funds for the Central Universities, Peking University” (grant No. 7100604896). Z.H. acknowledges support by US NSF grant AST-2006176 and by NASA grant Nos. 80NSSC24K0440 and 80NSSC22K0822.","OA_place":"publisher","year":"2026","publication":"The Astrophysical Journal","ddc":["520"],"article_processing_charge":"Yes","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"quality_controlled":"1","arxiv":1,"title":"The emergence of Little Red Dots from binary massive black holes","author":[{"full_name":"Inayoshi, Kohei","first_name":"Kohei","last_name":"Inayoshi"},{"full_name":"Shangguan, Jinyi","first_name":"Jinyi","last_name":"Shangguan"},{"full_name":"Chen, Xian","last_name":"Chen","first_name":"Xian"},{"first_name":"Luis C.","last_name":"Ho","full_name":"Ho, Luis C."},{"last_name":"Haiman","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","full_name":"Haiman, Zoltán","orcid":"0000-0003-3633-5403"}],"date_published":"2026-05-01T00:00:00Z","DOAJ_listed":"1","type":"journal_article","has_accepted_license":"1"},{"OA_place":"publisher","acknowledgement":"The technical assistance by Tanja Wagner and Elena Lilliu is gratefully acknowledged. This research was funded in whole or in part by the Austrian Science Fund (FWF) (P36145 to H.K., PAT8605623 to M.H. and P33799 to A.V.K.]. Open Access funding provided by Medical University of Vienna and the Austrian Science Fund (FWF). Deposited in PMC for immediate release.","year":"2026","_id":"21860","citation":{"chicago":"Goeschl, Vanessa, Matej Hotka, Bernhard Hochreiter, Karlheinz Hilber, Stefan Boehm, Andrey V. Kozlov, and Helmut Kubista. “α-Ketoglutarate Dehydrogenase Complex Activity Modulates Glutamate Excitotoxicity via Metabotropic Regulation of NMDA Receptors in Primary Cultures.” <i>Journal of Cell Science</i>. The Company of Biologists, 2026. <a href=\"https://doi.org/10.1242/jcs.264420\">https://doi.org/10.1242/jcs.264420</a>.","ama":"Goeschl V, Hotka M, Hochreiter B, et al. α-ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures. <i>Journal of Cell Science</i>. 2026;139(8). doi:<a href=\"https://doi.org/10.1242/jcs.264420\">10.1242/jcs.264420</a>","mla":"Goeschl, Vanessa, et al. “α-Ketoglutarate Dehydrogenase Complex Activity Modulates Glutamate Excitotoxicity via Metabotropic Regulation of NMDA Receptors in Primary Cultures.” <i>Journal of Cell Science</i>, vol. 139, no. 8, jcs264420, The Company of Biologists, 2026, doi:<a href=\"https://doi.org/10.1242/jcs.264420\">10.1242/jcs.264420</a>.","ieee":"V. Goeschl <i>et al.</i>, “α-ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures,” <i>Journal of Cell Science</i>, vol. 139, no. 8. The Company of Biologists, 2026.","short":"V. Goeschl, M. Hotka, B. Hochreiter, K. Hilber, S. Boehm, A.V. Kozlov, H. Kubista, Journal of Cell Science 139 (2026).","apa":"Goeschl, V., Hotka, M., Hochreiter, B., Hilber, K., Boehm, S., Kozlov, A. V., &#38; Kubista, H. (2026). α-ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures. <i>Journal of Cell Science</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.264420\">https://doi.org/10.1242/jcs.264420</a>","ista":"Goeschl V, Hotka M, Hochreiter B, Hilber K, Boehm S, Kozlov AV, Kubista H. 2026. α-ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures. Journal of Cell Science. 139(8), jcs264420."},"date_updated":"2026-05-12T06:40:18Z","month":"04","language":[{"iso":"eng"}],"publisher":"The Company of Biologists","file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","date_updated":"2026-05-12T06:27:54Z","success":1,"file_name":"2026_JourCellScience_Goeschl.pdf","date_created":"2026-05-12T06:27:54Z","file_size":1957057,"checksum":"8db35c97588c2f6ef88c7e8d5924cf8c","file_id":"21861","creator":"dernst"}],"author":[{"first_name":"Vanessa","last_name":"Goeschl","full_name":"Goeschl, Vanessa"},{"last_name":"Hotka","first_name":"Matej","full_name":"Hotka, Matej"},{"full_name":"Hochreiter, Bernhard","id":"e6cab3de-17f6-11ed-9210-c1e42e045e9d","first_name":"Bernhard","last_name":"Hochreiter"},{"last_name":"Hilber","first_name":"Karlheinz","full_name":"Hilber, Karlheinz"},{"full_name":"Boehm, Stefan","first_name":"Stefan","last_name":"Boehm"},{"full_name":"Kozlov, Andrey V.","first_name":"Andrey V.","last_name":"Kozlov"},{"full_name":"Kubista, Helmut","first_name":"Helmut","last_name":"Kubista"}],"title":"α-ketoglutarate dehydrogenase complex activity modulates glutamate excitotoxicity via metabotropic regulation of NMDA receptors in primary cultures","has_accepted_license":"1","type":"journal_article","date_published":"2026-04-27T00:00:00Z","ddc":["570"],"publication":"Journal of Cell Science","quality_controlled":"1","publication_identifier":{"eissn":["1477-9137"],"issn":["0021-9533"]},"article_processing_charge":"Yes (via OA deal)","issue":"8","PlanS_conform":"1","file_date_updated":"2026-05-12T06:27:54Z","oa":1,"status":"public","publication_status":"published","day":"27","department":[{"_id":"Bio"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1242/jcs.264420","oa_version":"Published Version","pmid":1,"OA_type":"hybrid","abstract":[{"text":"Glutamate excitotoxicity is a cell death mechanism triggered by accumulation of glutamate in the extracellular space. The α-ketoglutarate dehydrogenase complex (αKGDHC), an enzyme of the tricarboxylic acid cycle, represents a branching point controlling glutamate formation and its consumption as a fuel. Hence, modulation of the activity of αKGDHC might alter the amount of glutamate available for excitotoxic effects. To address this hypothesis, hippocampal neurons in primary co-culture with glial cells were exposed to zero-Mg2 buffer to elicit excitotoxicity through N-methyl-D-aspartic acid (NMDA) receptor disinhibition. Pretreatment of the cultures with succinyl phosphonate, to inhibit αKGDHC, enhanced excitotoxity, whereas promotion of αKGDHC activity by pretreatment with thiamine caused an opposite action. Moreover, NMDA receptor currents – but not those mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors – were potentiated in neurons with impaired αKGDHC activity and diminished in neurons with boosted αKGDHC activity. The sensitization of NMDA receptors involved mGluR1 activation and was accompanied by enhanced neuronal discharge activity, elevated basal cytosolic Ca2+ levels, and augmented Ca2+ responses evoked by glutamate application. These results suggest that mGluR1-mediated potentiation of NMDA receptors contributes to a mechanism by which inhibition of αKGDHC might exacerbate glutamate excitotoxicity.","lang":"eng"}],"article_number":"jcs264420","article_type":"original","volume":139,"date_created":"2026-05-11T10:52:27Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"pmid":["41834724"]},"scopus_import":"1","intvolume":"       139"},{"file":[{"file_id":"21862","creator":"dernst","file_name":"2026_PublAstronomicalSocAustralia_Kara.pdf","date_created":"2026-05-12T06:54:10Z","checksum":"f8f3cd3765948e8b276176c71c9d4e02","file_size":3681016,"date_updated":"2026-05-12T06:54:10Z","access_level":"open_access","success":1,"content_type":"application/pdf","relation":"main_file"}],"publisher":"Cambridge University Press","language":[{"iso":"eng"}],"month":"03","_id":"21842","citation":{"ieee":"J. Kára <i>et al.</i>, “A study of transients from ground-based surveys reveals new ultra-compact accreting white dwarf binaries,” <i>Publications of the Astronomical Society of Australia</i>, vol. 43. Cambridge University Press, 2026.","mla":"Kára, Jan, et al. “A Study of Transients from Ground-Based Surveys Reveals New Ultra-Compact Accreting White Dwarf Binaries.” <i>Publications of the Astronomical Society of Australia</i>, vol. 43, e052, Cambridge University Press, 2026, doi:<a href=\"https://doi.org/10.1017/pasa.2026.10184\">10.1017/pasa.2026.10184</a>.","ama":"Kára J, Rivera Sandoval L, Mendoza W, et al. A study of transients from ground-based surveys reveals new ultra-compact accreting white dwarf binaries. <i>Publications of the Astronomical Society of Australia</i>. 2026;43. doi:<a href=\"https://doi.org/10.1017/pasa.2026.10184\">10.1017/pasa.2026.10184</a>","ista":"Kára J, Rivera Sandoval L, Mendoza W, Maccarone T, Pichardo Marcano M, Salazar Manzano LE, Oelkers RJ, van Roestel JC. 2026. A study of transients from ground-based surveys reveals new ultra-compact accreting white dwarf binaries. Publications of the Astronomical Society of Australia. 43, e052.","apa":"Kára, J., Rivera Sandoval, L., Mendoza, W., Maccarone, T., Pichardo Marcano, M., Salazar Manzano, L. E., … van Roestel, J. C. (2026). A study of transients from ground-based surveys reveals new ultra-compact accreting white dwarf binaries. <i>Publications of the Astronomical Society of Australia</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/pasa.2026.10184\">https://doi.org/10.1017/pasa.2026.10184</a>","short":"J. Kára, L. Rivera Sandoval, W. Mendoza, T. Maccarone, M. Pichardo Marcano, L.E. Salazar Manzano, R.J. Oelkers, J.C. van Roestel, Publications of the Astronomical Society of Australia 43 (2026).","chicago":"Kára, Jan, Liliana Rivera Sandoval, Wendy Mendoza, Thomas Maccarone, Manuel Pichardo Marcano, Luis E. Salazar Manzano, Ryan J. Oelkers, and Joannes C van Roestel. “A Study of Transients from Ground-Based Surveys Reveals New Ultra-Compact Accreting White Dwarf Binaries.” <i>Publications of the Astronomical Society of Australia</i>. Cambridge University Press, 2026. <a href=\"https://doi.org/10.1017/pasa.2026.10184\">https://doi.org/10.1017/pasa.2026.10184</a>."},"date_updated":"2026-05-12T06:57:40Z","year":"2026","OA_place":"publisher","acknowledgement":"We are grateful to the anonymous referee for providing\r\nus with useful comments and suggestions that improved our manuscript.\r\nJK and LRS acknowledge support from NASA grants NNH22ZDA001N-6152\r\nand 80NSSC24K0638. MPM is partially supported by the Swiss National\r\nScience Foundation IZSTZ0_216537 and by UNAM PAPIIT-IG101224. Based\r\non observations obtained at the international Gemini Observatory, a program\r\nof NSF NOIRLab, which is managed by the Association of Universities for\r\nResearch in Astronomy (AURA) under a cooperative agreement with the U.S.\r\nNational Science Foundation on behalf of the Gemini Observatory partnership:\r\nthe U.S. National Science Foundation (United States), National Research\r\nCouncil (Canada), Agencia Nacional de Investigación y Desarrollo (Chile), Ministerio de Ciencia, Tecnología e Innovación (Argentina), Ministério\r\nda Ciência, Tecnologia, Inovações e Comunicações (Brazil), and Korea\r\nAstronomy and Space Science Institute (Republic of Korea). The Gemini\r\ndata were obtained from programs GN-2023B-Q-310 and GS-2024A-Q-311\r\n(PI: Rivera Sandoval) and processed using DRAGONS (Data Reduction for\r\nAstronomy from Gemini Observatory North and South) The Digitized Sky\r\nSurveys were produced at the Space Telescope Science Institute under U.S.\r\nGovernment grant NAG W-2166. The images of these surveys are based on\r\nphotographic data obtained using the Oschin Schmidt Telescope on Palomar\r\nMountain and the UK Schmidt Telescope. The plates were processed into the\r\npresent compressed digital form with the permission of these institutions.\r\nThe National Geographic Society – Palomar Observatory Sky Atlas (POSS-I)\r\nwas made by the California Institute of Technology with grants from the\r\nNational Geographic Society. The Second Palomar Observatory Sky Survey\r\n(POSS-II) was made by the California Institute of Technology with funds\r\nfrom the National Science Foundation, the National Geographic Society, the\r\nSloan Foundation, the Samuel Oschin Foundation, and the Eastman Kodak\r\nCorporation. The Oschin Schmidt Telescope is operated by the California\r\nInstitute of Technology and Palomar Observatory. The UK Schmidt Telescope\r\nwas operated by the Royal Observatory Edinburgh, with funding from the\r\nUK Science and Engineering Research Council (later the UK Particle Physics\r\nand Astronomy Research Council), until 1988 June, and thereafter by the\r\nAnglo-Australian Observatory. The blue plates of the southern Sky Atlas\r\nand its Equatorial Extension (together known as the SERC-J), as well as the\r\nEquatorial Red (ER), and the Second Epoch [red] Survey (SES) were all taken\r\nwith the UK Schmidt. Supplemental funding for sky-survey work at the ST\r\nScI is provided by the European Southern Observatory. Based on observations\r\nobtained with the Samuel Oschin Telescope 48-inch and the 60-inch Telescope\r\nat the Palomar Observatory as part of the Zwicky Transient Facility project.\r\nZTF is supported by the National Science Foundation under Grants No. AST-\r\n1440341 and AST-2034437 and a collaboration including current partners\r\nCaltech, IPAC, the Oskar Klein Center at Stockholm University, the University\r\nof Maryland, University of California, Berkeley, the University of Wisconsin\r\nat Milwaukee, University of Warwick, Ruhr University, Cornell University,\r\nNorthwestern University, and Drexel University. Operations are conducted\r\nby COO, IPAC, and UW. This work has used data from the European\r\nSpace Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia),\r\nprocessed by the Gaia Data Processing and Analysis Consortium (DPAC,\r\nhttps://www.cosmos.esa.int/web/gaia/dpac/consortium). Funding for the\r\nDPAC has been provided by national institutions, in particular, the institutions\r\nparticipating in the Gaia Multilateral Agreement. We acknowledge with\r\nthanks the variable star observations from the AAVSO International Database\r\ncontributed by observers worldwide and used in this research. This paper\r\nincludes data collected by the TESS mission. Funding for the TESS mission\r\nis provided by the NASA Science Mission Directorate. Some of the data\r\npresented in this paper were obtained from the B. Mikulski Archive for Space\r\nTelescopes (MAST). This research has made use of the SIMBAD database,\r\noperated at CDS, Strasbourg, France. This research has made use of ‘Aladin\r\nsky atlas’ developed at CDS, Strasbourg Observatory, France. This research\r\nhas made use of the VizieR catalogue access tool, CDS, Strasbourg, France.","article_processing_charge":"Yes (in subscription journal)","publication_identifier":{"eissn":["1448-6083"],"issn":["1323-3580"]},"quality_controlled":"1","publication":"Publications of the Astronomical Society of Australia","ddc":["520"],"date_published":"2026-03-27T00:00:00Z","type":"journal_article","has_accepted_license":"1","title":"A study of transients from ground-based surveys reveals new ultra-compact accreting white dwarf binaries","author":[{"last_name":"Kára","first_name":"Jan","full_name":"Kára, Jan"},{"first_name":"Liliana","last_name":"Rivera Sandoval","full_name":"Rivera Sandoval, Liliana"},{"first_name":"Wendy","last_name":"Mendoza","full_name":"Mendoza, Wendy"},{"full_name":"Maccarone, Thomas","first_name":"Thomas","last_name":"Maccarone"},{"full_name":"Pichardo Marcano, Manuel","last_name":"Pichardo Marcano","first_name":"Manuel"},{"first_name":"Luis E.","last_name":"Salazar Manzano","full_name":"Salazar Manzano, Luis E."},{"last_name":"Oelkers","first_name":"Ryan J.","full_name":"Oelkers, Ryan J."},{"first_name":"Joannes C","id":"4d122fc8-6083-11f0-87a5-97d68b860333","last_name":"van Roestel","full_name":"van Roestel, Joannes C"}],"doi":"10.1017/pasa.2026.10184","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"IlCa"}],"day":"27","publication_status":"published","status":"public","file_date_updated":"2026-05-12T06:54:10Z","oa":1,"PlanS_conform":"1","intvolume":"        43","scopus_import":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_created":"2026-05-07T08:55:00Z","volume":43,"article_type":"original","article_number":"e052","abstract":[{"text":"AM CVn stars are ultra-compact semi-detached binaries consisting of a white dwarf primary and a hydrogen-depleted secondary. In this\r\npaper, we present spectroscopic and photometric results of 15 transient sources pre-classified as AM CVn candidates. Our analysis confirms\r\n9 systems of the type AM CVn, 3 hydrogen-rich cataclysmic variables (accreting white dwarfs with near-main-sequence stars for donors),\r\nand 3 systems that could be evolved cataclysmic variables. Eight of the AM CVn stars are analysed spectroscopically for the first time,\r\nwhich increases the number of spectroscopically confirmed AM CVns by about 10%. TESS data revealed the orbital period of the AM CVn\r\nstar ASASSN-20pv to be Porb =27.282 min, which helps to constrain the possible values of its mass ratio. TESS also helped to determine\r\nthe superhump periods of one AM CVn star (ASASSN-19ct, Psh =30.94 min) and two cataclysmic variables we classify as WZ Sge stars\r\n(Psh =90.77 min for ZTF18aaaasnn and Psh =91.6min for ASASSN-15na).We identified very different abundances in the spectra of theAM\r\nCVns binaries ASASSN-15kf and ASASSN-20pv (both Porb ∼27.5min), suggesting different type of donors. Six of the studied AMCVns are\r\nX-ray sources, which helped to determine their mass accretion rates. Photometry shows that the duration of all the superoutbursts detected\r\nin the AM CVns is consistent with expectations from the disc instability model. Finally, we provide refined criteria for the identification of\r\nnew systems using all-sky surveys such as LSST.","lang":"eng"}],"OA_type":"hybrid","oa_version":"Published Version"},{"file_date_updated":"2026-05-13T06:11:26Z","oa":1,"year":"2026","day":"13","file":[{"content_type":"application/pdf","relation":"main_file","date_updated":"2026-05-12T12:43:32Z","access_level":"open_access","success":1,"file_name":"Main_text_and_figures.pdf","date_created":"2026-05-12T12:43:32Z","checksum":"1512170d78f9f31025c87b3a03c62f0c","file_size":10079104,"file_id":"21865","creator":"nhino"},{"relation":"main_file","content_type":"application/pdf","success":1,"date_updated":"2026-05-12T12:44:02Z","access_level":"open_access","date_created":"2026-05-12T12:44:02Z","checksum":"bee92c26b42433e4ff5ca3f17e3f0640","file_size":1820979,"file_name":"Supplementary_figures.pdf","creator":"nhino","file_id":"21866"},{"file_name":"Supplementary_Video1.mp4","date_created":"2026-05-12T12:44:09Z","checksum":"9d9ab89c372142f2ffb6c8c625334d7f","file_size":10349451,"file_id":"21867","creator":"nhino","content_type":"video/mp4","relation":"main_file","access_level":"open_access","date_updated":"2026-05-12T12:44:09Z","success":1},{"relation":"main_file","content_type":"text/plain","access_level":"closed","date_updated":"2026-05-13T06:11:26Z","checksum":"3e220d1cc8f883bef02eaf5d810cd911","file_size":91,"date_created":"2026-05-13T06:11:26Z","file_name":"authors.txt","creator":"dernst","file_id":"21874"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"chicago":"Anonymous, 1, 2 Anonymous, and 3 Anonymous. <i>Mechanism of Tissue Tension Homeostasis during Embryogenesis</i>. Institute of Science and Technology Austria, n.d.","ista":"Anonymous 1, Anonymous 2, Anonymous 3. Mechanism of tissue tension homeostasis during embryogenesis, Institute of Science and Technology Austria, 32p.","apa":"Anonymous, 1, Anonymous, 2, &#38; Anonymous, 3. (n.d.). <i>Mechanism of tissue tension homeostasis during embryogenesis</i>. Institute of Science and Technology Austria.","short":"1 Anonymous, 2 Anonymous, 3 Anonymous, Mechanism of Tissue Tension Homeostasis during Embryogenesis, Institute of Science and Technology Austria, n.d.","ieee":"1 Anonymous, 2 Anonymous, and 3 Anonymous, <i>Mechanism of tissue tension homeostasis during embryogenesis</i>. Institute of Science and Technology Austria.","ama":"Anonymous 1, Anonymous 2, Anonymous 3. <i>Mechanism of Tissue Tension Homeostasis during Embryogenesis</i>. Institute of Science and Technology Austria","mla":"Anonymous, 1, et al. <i>Mechanism of Tissue Tension Homeostasis during Embryogenesis</i>. Institute of Science and Technology Austria."},"_id":"21864","date_updated":"2026-05-13T06:26:39Z","status":"public","page":"32","month":"05","publication_status":"draft","language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","type":"technical_report","date_created":"2026-05-12T12:52:44Z","date_published":"2026-05-13T00:00:00Z","oa_version":"Preprint","author":[{"full_name":"Anonymous, 1","last_name":"Anonymous","first_name":"1"},{"full_name":"Anonymous, 2","last_name":"Anonymous","first_name":"2"},{"first_name":"3","last_name":"Anonymous","full_name":"Anonymous, 3"}],"title":"Mechanism of tissue tension homeostasis during embryogenesis","alternative_title":["ISTA Technical Report"],"publication_identifier":{"eissn":["2664-1690"]},"article_processing_charge":"No","ddc":["570"]},{"publication_status":"published","status":"public","department":[{"_id":"FrPe"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.5194/tc-20-1895-2026","day":"02","PlanS_conform":"1","issue":"3","file_date_updated":"2026-05-18T06:07:53Z","oa":1,"scopus_import":"1","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"intvolume":"        20","OA_type":"gold","oa_version":"Published Version","article_type":"original","date_created":"2026-05-07T08:48:38Z","volume":20,"abstract":[{"text":"In a warming world of glacier changes, the scientific community has dedicated increasing attention to debris-covered glaciers and their response to climate. A variety of models with distinct complexity and data requirements have been developed and widely used to simulate melt under debris at different sites and scales, but their skills have never been compared. As part of the activities of the International Association of Cryospheric Sciences (IACS) Debris Covered Glacier Working Group, we present an intercomparison exercise aimed at advancing our understanding of model skills in simulating ice melt under a debris layer. We compare 15 models with different complexity at nine sites in the European Alps, Caucasus, Chilean Andes, Nepalese Himalaya and the Southern Alps of New Zealand, over one melt season. We run the models with measured meteorological data from automatic weather stations and estimated or measured debris properties. We consider four main model categories: (i) energy balance models that calculate melt by solving the physics of heat transfer to the debris layer, but require a high amount of input data; (ii) a simplified energy balance model; (iii) enhanced temperature-index models; and (iv) simple empirical temperature-index models that have been extensively used given their low data requirement but require calibration of their empirical parameters. Model performance is evaluated using on-site measurements of sub-debris melt (for all models) and surface temperature (for models based on the surface energy balance). Our results show that physically-based energy balance models and empirical temperature-index models perform in a distinct manner. At one end of the spectrum, simple temperature-index models are accurate when recalibrated or when using site-specific literature parameters, and show poor results when parameters are uncalibrated. At the other end, energy balance models show a range of performance: the most accurate energy balance models are those with the highest degree of complexity at the atmosphere-debris interface. An important data gap emerged from our experiment: the poor performance of all models at three sites was related to the poor knowledge of debris properties, and specifically of thermal conductivity. Future work should focus on both: (i) consistent data acquisition to evaluate existing models and support new model developments; (ii) advancing models by accounting for processes such as debris-snow interactions, moisture in the debris and refreezing. We suggest that a systematic effort of model development using a common model framework could be carried out in phase II of the Working Group.","lang":"eng"}],"language":[{"iso":"eng"}],"publisher":"Copernicus Publications","corr_author":"1","_id":"21837","date_updated":"2026-05-18T06:12:56Z","citation":{"chicago":"Pellicciotti, Francesca, Adrià Fontrodona-Bach, David R. Rounce, Catriona Louise Fyffe, Leif S. Anderson, Álvaro Ayala, Ben W. Brock, et al. “DCG-MIP: The Debris-Covered Glacier Melt Model Intercomparison Experiment.” <i>The Cryosphere</i>. Copernicus Publications, 2026. <a href=\"https://doi.org/10.5194/tc-20-1895-2026\">https://doi.org/10.5194/tc-20-1895-2026</a>.","mla":"Pellicciotti, Francesca, et al. “DCG-MIP: The Debris-Covered Glacier Melt Model Intercomparison Experiment.” <i>The Cryosphere</i>, vol. 20, no. 3, Copernicus Publications, 2026, pp. 1895–928, doi:<a href=\"https://doi.org/10.5194/tc-20-1895-2026\">10.5194/tc-20-1895-2026</a>.","ama":"Pellicciotti F, Fontrodona-Bach A, Rounce DR, et al. DCG-MIP: The debris-covered glacier melt model intercomparison experiment. <i>The Cryosphere</i>. 2026;20(3):1895-1928. doi:<a href=\"https://doi.org/10.5194/tc-20-1895-2026\">10.5194/tc-20-1895-2026</a>","ieee":"F. Pellicciotti <i>et al.</i>, “DCG-MIP: The debris-covered glacier melt model intercomparison experiment,” <i>The Cryosphere</i>, vol. 20, no. 3. Copernicus Publications, pp. 1895–1928, 2026.","apa":"Pellicciotti, F., Fontrodona-Bach, A., Rounce, D. R., Fyffe, C. L., Anderson, L. S., Ayala, Á., … Winter-Billington, A. (2026). DCG-MIP: The debris-covered glacier melt model intercomparison experiment. <i>The Cryosphere</i>. Copernicus Publications. <a href=\"https://doi.org/10.5194/tc-20-1895-2026\">https://doi.org/10.5194/tc-20-1895-2026</a>","short":"F. Pellicciotti, A. Fontrodona-Bach, D.R. Rounce, C.L. Fyffe, L.S. Anderson, Á. Ayala, B.W. Brock, P. Buri, S. Fugger, K. Fujita, P. GANTAYAT, A.R. Groos, W. Immerzeel, M. Kneib, C. Mayer, S. MacDonell, M. McCarthy, J. McPhee, E. Miles, H. Purdie, E. Rets, A. Sakai, T. Shaw, J. Steiner, P. Wagnon, A. Winter-Billington, The Cryosphere 20 (2026) 1895–1928.","ista":"Pellicciotti F, Fontrodona-Bach A, Rounce DR, Fyffe CL, Anderson LS, Ayala Á, Brock BW, Buri P, Fugger S, Fujita K, GANTAYAT P, Groos AR, Immerzeel W, Kneib M, Mayer C, MacDonell S, McCarthy M, McPhee J, Miles E, Purdie H, Rets E, Sakai A, Shaw T, Steiner J, Wagnon P, Winter-Billington A. 2026. DCG-MIP: The debris-covered glacier melt model intercomparison experiment. The Cryosphere. 20(3), 1895–1928."},"page":"1895-1928","month":"04","file":[{"date_created":"2026-05-18T06:07:53Z","file_size":3168394,"checksum":"f15abad4ee360d41a3e8794f068711fc","file_name":"2026_Cryosphere_Pellicciotti.pdf","creator":"dernst","file_id":"21886","relation":"main_file","content_type":"application/pdf","success":1,"date_updated":"2026-05-18T06:07:53Z","access_level":"open_access"}],"OA_place":"publisher","acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme grant agreement No\r\n772751, RAVEN, “Rapid mass losses of debris covered glaciers in\r\nHigh Mountain Asia”. It was also supported by the SNSF RENOIR\r\nproject “Resolving the thickness of debris on Earth’s glaciers and\r\nits rate of change (RENOIR)”, project number 204322.\r\nDavid Rounce received support from NASA-ROSES program\r\ngrants NNX17AB27G and 80NSSC17K0566. Walter Immerzeel\r\nand Jakob Steiner acknowledge support from the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation program (grant agreement no. 676819).\r\nBen Brock acknowledges support from the EU/FP7 ACQWA\r\n(Assessing Climate impacts on the Quantity and quality of WAter) project, NERC grant NE/C514282/1, the British Council-Italian\r\nMinistry of University and Research Partnership programme and\r\nthe Carnegie Trust for the Universities of Scotland.\r\nThe authors acknowledge the International Association of\r\nCryospheric Sciences (IACS) for supporting the creation of the\r\nDebris-Covered Glaciers Working Group (DCG-WG) which enabled this model intercomparison experiment.\r\nThe authors thank Martin Heynen for producing Figs. 3 and 4.\r\nThe authors thank Duncan Quincey and Richard Essery for their\r\nconstructive feedback and comments.\r\n","year":"2026","publication":"The Cryosphere","ddc":["550"],"article_processing_charge":"Yes","quality_controlled":"1","publication_identifier":{"eissn":["1994-0424"]},"author":[{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","orcid":"0000-0002-5554-8087"},{"full_name":"Fontrodona-Bach, Adrià","first_name":"Adrià","id":"f06891fd-9f42-11ee-8632-a20971c43046","last_name":"Fontrodona-Bach"},{"full_name":"Rounce, David R.","last_name":"Rounce","first_name":"David R."},{"id":"001b0422-8d15-11ed-bc51-cab6c037a228","first_name":"Catriona Louise","last_name":"Fyffe","full_name":"Fyffe, Catriona Louise"},{"full_name":"Anderson, Leif S.","last_name":"Anderson","first_name":"Leif S."},{"full_name":"Ayala, Álvaro","first_name":"Álvaro","last_name":"Ayala"},{"full_name":"Brock, Ben W.","last_name":"Brock","first_name":"Ben W."},{"last_name":"Buri","first_name":"Pascal","full_name":"Buri, Pascal"},{"full_name":"Fugger, Stefan","last_name":"Fugger","first_name":"Stefan"},{"first_name":"Koji","last_name":"Fujita","full_name":"Fujita, Koji"},{"full_name":"GANTAYAT, PRATEEK","first_name":"PRATEEK","id":"02734268-3e8d-11ef-80a1-cec4a088d004","last_name":"GANTAYAT"},{"first_name":"Alexander R.","last_name":"Groos","full_name":"Groos, Alexander R."},{"first_name":"Walter","last_name":"Immerzeel","full_name":"Immerzeel, Walter"},{"first_name":"Marin","last_name":"Kneib","full_name":"Kneib, Marin"},{"full_name":"Mayer, Christoph","last_name":"Mayer","first_name":"Christoph"},{"full_name":"MacDonell, Shelley","first_name":"Shelley","last_name":"MacDonell"},{"last_name":"McCarthy","id":"22a2674a-61ce-11ee-94b5-d18813baf16f","first_name":"Michael","full_name":"McCarthy, Michael"},{"full_name":"McPhee, James","first_name":"James","last_name":"McPhee"},{"first_name":"Evan","last_name":"Miles","full_name":"Miles, Evan"},{"first_name":"Heather","last_name":"Purdie","full_name":"Purdie, Heather"},{"first_name":"Ekaterina","last_name":"Rets","full_name":"Rets, Ekaterina"},{"first_name":"Akiko","last_name":"Sakai","full_name":"Sakai, Akiko"},{"orcid":"0000-0001-7640-6152","full_name":"Shaw, Thomas","last_name":"Shaw","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","first_name":"Thomas"},{"first_name":"Jakob","last_name":"Steiner","full_name":"Steiner, Jakob"},{"last_name":"Wagnon","first_name":"Patrick","full_name":"Wagnon, Patrick"},{"full_name":"Winter-Billington, Alex","last_name":"Winter-Billington","first_name":"Alex"}],"title":"DCG-MIP: The debris-covered glacier melt model intercomparison experiment","DOAJ_listed":"1","date_published":"2026-04-02T00:00:00Z","type":"journal_article","has_accepted_license":"1"},{"intvolume":"        46","scopus_import":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"external_id":{"pmid":["41943460"]},"article_type":"original","volume":46,"date_created":"2026-05-07T08:51:47Z","abstract":[{"text":"Background & Aims: To develop and validate a CT-based radiomics model to assess HVPG and predict a composite endpoint of liver-related events (LRE: decompensation and liver-related death) in patients with cirrhosis.\r\n\r\nMethods: This retrospective study included 357 cirrhosis patients, who received invasive HVPG measurements, 120 liver-healthy controls (training cohort) and 85 and 100 cirrhosis patients (internal and external validation cohorts, respectively), and contrast-enhanced abdominal CTs. After volumetric segmentation of the liver and spleen on CT, Bayesian parameter optimization was used for selection of extracted features and hyperparameter tuning in random forest or elastic net models. Prediction accuracy was evaluated using Pearson correlation coefficients of predicted (’radio-HVPG’) and invasive HVPG. Discrimination between relevant HVPG cut-offs was determined by receiver operating characteristic (ROC) analysis. The predictive value of radio-HVPG and invasive-HVPG for LRE was compared using Cox regression models.\r\n\r\nResults: Radio-HVPG, predicted by an optimized random forest model based on 74 selected CT features, correlated with invasive-HVPG and detected clinically significant portal hypertension (CSPH: HVPG ≥ 10 mmHg) on the internal (Pearson r = 0.63, AUC 0.89 [95% CI: 0.81–0.96]) and external (Pearson r = 0.62, AUC 0.80 [95% CI: 0.64–0.91]) validation cohorts. Radio-HVPG predicted LRE when adjusting for MELD and albumin (adjusted HR: 1.14 [95% CI: 1.04–1.25], p = 0.005) and performed similarly to invasive-HVPG.\r\n\r\nConclusions: Radiomic features accurately predict HVPG in patients with cirrhosis and allow risk stratification for LRE in a radiomics-clinical signature.","lang":"eng"}],"article_number":"e70633","OA_type":"hybrid","oa_version":"Published Version","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1111/liv.70633","day":"01","publication_status":"published","status":"public","keyword":["computed tomography","liver","portal hypertension","radiomics","spleen"],"file_date_updated":"2026-05-18T07:10:31Z","oa":1,"issue":"5","article_processing_charge":"Yes (via OA deal)","quality_controlled":"1","publication_identifier":{"issn":["1478-3223"],"eissn":["1478-3231"]},"publication":"Liver International","ddc":["570"],"date_published":"2026-05-01T00:00:00Z","type":"journal_article","has_accepted_license":"1","author":[{"full_name":"Sin, Celine","first_name":"Celine","last_name":"Sin"},{"full_name":"Watzenboeck, Martin Luther","first_name":"Martin Luther","last_name":"Watzenboeck"},{"orcid":"0000-0002-7778-3221","full_name":"Iofinova, Eugenia B","id":"f9a17499-f6e0-11ea-865d-fdf9a3f77117","first_name":"Eugenia B","last_name":"Iofinova"},{"full_name":"Balcar, Lorenz","first_name":"Lorenz","last_name":"Balcar"},{"full_name":"Semmler, Georg","last_name":"Semmler","first_name":"Georg"},{"last_name":"Scheiner","first_name":"Bernhard","full_name":"Scheiner, Bernhard"},{"full_name":"Lampichler, Katharina","last_name":"Lampichler","first_name":"Katharina"},{"last_name":"Mandorfer","first_name":"Mattias","full_name":"Mandorfer, Mattias"},{"full_name":"Moga, Lucile","first_name":"Lucile","last_name":"Moga"},{"first_name":"Pierre‐Emmanuel","last_name":"Rautou","full_name":"Rautou, Pierre‐Emmanuel"},{"first_name":"Maxime","last_name":"Ronot","full_name":"Ronot, Maxime"},{"first_name":"Jörg","last_name":"Menche","full_name":"Menche, Jörg"},{"first_name":"Thomas","last_name":"Reiberger","full_name":"Reiberger, Thomas"},{"full_name":"Scharitzer, Martina","first_name":"Martina","last_name":"Scharitzer"}],"title":"Radiomics‐based assessment of portal hypertension severity and risk stratification of cirrhotic patients using routine CT scans","file":[{"content_type":"application/pdf","relation":"main_file","date_updated":"2026-05-18T07:10:31Z","access_level":"open_access","success":1,"file_name":"2026_LiverInternational_Sin.pdf","date_created":"2026-05-18T07:10:31Z","file_size":3550462,"checksum":"fafcc0b88b8e8caed85849627305d9ba","file_id":"21888","creator":"dernst"}],"language":[{"iso":"eng"}],"publisher":"Wiley","_id":"21839","citation":{"ama":"Sin C, Watzenboeck ML, Iofinova EB, et al. Radiomics‐based assessment of portal hypertension severity and risk stratification of cirrhotic patients using routine CT scans. <i>Liver International</i>. 2026;46(5). doi:<a href=\"https://doi.org/10.1111/liv.70633\">10.1111/liv.70633</a>","mla":"Sin, Celine, et al. “Radiomics‐based Assessment of Portal Hypertension Severity and Risk Stratification of Cirrhotic Patients Using Routine CT Scans.” <i>Liver International</i>, vol. 46, no. 5, e70633, Wiley, 2026, doi:<a href=\"https://doi.org/10.1111/liv.70633\">10.1111/liv.70633</a>.","ieee":"C. Sin <i>et al.</i>, “Radiomics‐based assessment of portal hypertension severity and risk stratification of cirrhotic patients using routine CT scans,” <i>Liver International</i>, vol. 46, no. 5. Wiley, 2026.","apa":"Sin, C., Watzenboeck, M. L., Iofinova, E. B., Balcar, L., Semmler, G., Scheiner, B., … Scharitzer, M. (2026). Radiomics‐based assessment of portal hypertension severity and risk stratification of cirrhotic patients using routine CT scans. <i>Liver International</i>. Wiley. <a href=\"https://doi.org/10.1111/liv.70633\">https://doi.org/10.1111/liv.70633</a>","short":"C. Sin, M.L. Watzenboeck, E.B. Iofinova, L. Balcar, G. Semmler, B. Scheiner, K. Lampichler, M. Mandorfer, L. Moga, P. Rautou, M. Ronot, J. Menche, T. Reiberger, M. Scharitzer, Liver International 46 (2026).","ista":"Sin C, Watzenboeck ML, Iofinova EB, Balcar L, Semmler G, Scheiner B, Lampichler K, Mandorfer M, Moga L, Rautou P, Ronot M, Menche J, Reiberger T, Scharitzer M. 2026. Radiomics‐based assessment of portal hypertension severity and risk stratification of cirrhotic patients using routine CT scans. Liver International. 46(5), e70633.","chicago":"Sin, Celine, Martin Luther Watzenboeck, Eugenia B Iofinova, Lorenz Balcar, Georg Semmler, Bernhard Scheiner, Katharina Lampichler, et al. “Radiomics‐based Assessment of Portal Hypertension Severity and Risk Stratification of Cirrhotic Patients Using Routine CT Scans.” <i>Liver International</i>. Wiley, 2026. <a href=\"https://doi.org/10.1111/liv.70633\">https://doi.org/10.1111/liv.70633</a>."},"date_updated":"2026-05-18T07:20:20Z","month":"05","year":"2026","OA_place":"publisher","acknowledgement":"The computational results presented were partly obtained using the CLIP cluster (https://clip.science/). The authors thank Clemens Watzenboeck from the Medical University of Vienna for the assistance in code upload and repository maintenance. The authors dedicate this work to the memory of Martin Watzenboeck, who served as first author and whose vision and scientific rigor were fundamental to the conception and completion of this study. Open Access funding provided by Medizinische Universitat Wien/KEMÖ. This work was supported by the Vienna Science and Technology Fund (WWTF) through projects VRG15-005 and NXT 19-008 granted to J.M and the Clinical Research Group MOTION, Medical University of Vienna, Vienna, Austria – a Clinical Research Group Programme project funded by the Ludwig Boltzmann Gesellschaft (Grant Nr LBG_KFG_22_32) with funds from the Fonds Zukunft Österreich.\r\n\r\nP-E.R.'s research laboratory is supported by the Fondation pour la Recherche Médicale (FRM EQU202303016287), “Institut National de la Santé et de la Recherche Médicale” (ATIP AVENIR), the “Agence Nationale de la Recherche” (ANR-18-CE14-0006-01, RHU QUID-NASH, ANR-18-IDEX-0001, ANR-22-CE14-0002) by « Émergence, Ville de Paris », by Fondation ARC, by the European Union's Horizon 2020 research and innovation programme under grant agreement No 847949 and by France 2030 RHU LIVER-TRACK."},{"intvolume":"       164","scopus_import":"1","external_id":{"arxiv":["2505.02478"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","date_created":"2026-05-07T08:53:03Z","volume":164,"abstract":[{"text":"The transport properties of nanofluidic channels are usually studied under constant (DC) voltage or pressure driving. However, the frequency response under sinusoidal (AC) drivings offers rich insights into the time-dependent transport mechanisms. Inspired by recent electrochemical approaches, we investigate the couplings between ionic and electronic transport under AC driving. We show that conduction electrons of the channel walls participate in ionic current via capacitive electrochemical coupling, defining a critical frequency and length scale where electron-dominated conductivity emerges. We further analyze how electron–ion coupling modifies electro-osmotic flows and demonstrate that fluctuation-induced momentum transfer between the electrolyte and wall electrons produces distinct AC transport signatures, depending on the charge carrier polarity. Altogether, we establish a frequency-dependent transport matrix that couples ionic, electronic, and hydrodynamic flows. These findings establish AC nanofluidic transport as a powerful probe of interfacial phenomena under confinement and suggest new directions for engineering nanofluidic functionalities through electron–electrolyte coupling.","lang":"eng"}],"article_number":"134704","OA_type":"hybrid","oa_version":"Published Version","department":[{"_id":"MiLe"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1063/5.0313352","day":"07","publication_status":"published","status":"public","oa":1,"file_date_updated":"2026-05-18T07:31:23Z","PlanS_conform":"1","issue":"13","article_processing_charge":"Yes (in subscription journal)","quality_controlled":"1","publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"publication":"The Journal of Chemical Physics","ddc":["530"],"date_published":"2026-04-07T00:00:00Z","has_accepted_license":"1","type":"journal_article","arxiv":1,"author":[{"full_name":"Coquinot, Baptiste","last_name":"Coquinot","id":"f8417bd4-f599-11ee-a482-b927e3ed1e8e","first_name":"Baptiste","orcid":"0000-0001-5524-596X"},{"last_name":"Lizée","first_name":"Mathieu","full_name":"Lizée, Mathieu"},{"last_name":"Bocquet","first_name":"Lydéric","full_name":"Bocquet, Lydéric"},{"full_name":"Kavokine, Nikita","last_name":"Kavokine","first_name":"Nikita"}],"title":"Electron–electrolyte coupling in AC transport through nanofluidic channels","file":[{"relation":"main_file","content_type":"application/pdf","success":1,"access_level":"open_access","date_updated":"2026-05-18T07:31:23Z","file_size":5497515,"checksum":"a896969c829be2a79859bd277f87b44c","date_created":"2026-05-18T07:31:23Z","file_name":"2026_JourChemPhysics_Coquinot.pdf","creator":"dernst","file_id":"21889"}],"language":[{"iso":"eng"}],"publisher":"AIP Publishing","_id":"21840","citation":{"chicago":"Coquinot, Baptiste, Mathieu Lizée, Lydéric Bocquet, and Nikita Kavokine. “Electron–Electrolyte Coupling in AC Transport through Nanofluidic Channels.” <i>The Journal of Chemical Physics</i>. AIP Publishing, 2026. <a href=\"https://doi.org/10.1063/5.0313352\">https://doi.org/10.1063/5.0313352</a>.","ieee":"B. Coquinot, M. Lizée, L. Bocquet, and N. Kavokine, “Electron–electrolyte coupling in AC transport through nanofluidic channels,” <i>The Journal of Chemical Physics</i>, vol. 164, no. 13. AIP Publishing, 2026.","mla":"Coquinot, Baptiste, et al. “Electron–Electrolyte Coupling in AC Transport through Nanofluidic Channels.” <i>The Journal of Chemical Physics</i>, vol. 164, no. 13, 134704, AIP Publishing, 2026, doi:<a href=\"https://doi.org/10.1063/5.0313352\">10.1063/5.0313352</a>.","ama":"Coquinot B, Lizée M, Bocquet L, Kavokine N. Electron–electrolyte coupling in AC transport through nanofluidic channels. <i>The Journal of Chemical Physics</i>. 2026;164(13). doi:<a href=\"https://doi.org/10.1063/5.0313352\">10.1063/5.0313352</a>","ista":"Coquinot B, Lizée M, Bocquet L, Kavokine N. 2026. Electron–electrolyte coupling in AC transport through nanofluidic channels. The Journal of Chemical Physics. 164(13), 134704.","apa":"Coquinot, B., Lizée, M., Bocquet, L., &#38; Kavokine, N. (2026). Electron–electrolyte coupling in AC transport through nanofluidic channels. <i>The Journal of Chemical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0313352\">https://doi.org/10.1063/5.0313352</a>","short":"B. Coquinot, M. Lizée, L. Bocquet, N. Kavokine, The Journal of Chemical Physics 164 (2026)."},"date_updated":"2026-05-18T07:34:57Z","month":"04","year":"2026","acknowledgement":"The authors thank Nicolas Chapuis for fruitful discussions. L.B. acknowledges support from the ERC project n-AQUA under Grant Agreement No. 101071937. B.C. acknowledges support from the CFM Foundation and the NOMIS Foundation. N.K. acknowledges support from the Swiss National Science Foundation (SNSF) under Grant No. CRSK-2_237930.","OA_place":"publisher"},{"issue":"3","oa":1,"file_date_updated":"2026-05-18T06:29:57Z","status":"public","publication_status":"published","day":"06","doi":"10.1002/syst.70037","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"RaKl"}],"oa_version":"Published Version","OA_type":"hybrid","article_number":"e70037","abstract":[{"lang":"eng","text":"We explore the use of a photoacid in a chemical reaction cycle, which allows for the controlled sol‐to‐gel transition of a saccharide aldehyde‐based self‐assembling system. The modulation of the pH with light enables to generate chemical fuels in situ, thus triggering monomer activation and gelation. Our efforts represent a promising step toward dissipative self‐assembled systems with a higher degree of spatiotemporal control."}],"volume":8,"date_created":"2026-05-07T08:51:01Z","article_type":"original","tmp":{"image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"intvolume":"         8","OA_place":"publisher","acknowledgement":"J.S.V. and T.M.H. acknowledge funding from ERC-2017-STG “Life-Cycle” (757910) and ERC-2022-CoG “Suprabot” (101087514). A.L-A. acknowledges the European Union's Horizon 2020 Research and Innovation Program under the Marie Skłodowska-Curie grant agreement no. 812868 for Ph.D. funding. R.K. acknowledges support through the Award for Research Cooperation and High Excellence in Science (ARCHES) from the Federal German Ministry and Research.","year":"2026","month":"04","date_updated":"2026-05-18T06:59:10Z","_id":"21838","citation":{"chicago":"Lopez‐Acosta, Alvaro, Jorge S. Valera, Rafal Klajn, and Thomas M. Hermans. “Photoacid‐mediated Controllable Gelation in a Chemical Reaction Cycle.” <i>ChemSystemsChem</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/syst.70037\">https://doi.org/10.1002/syst.70037</a>.","ista":"Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. 2026. Photoacid‐mediated controllable gelation in a chemical reaction cycle. ChemSystemsChem. 8(3), e70037.","short":"A. Lopez‐Acosta, J.S. Valera, R. Klajn, T.M. Hermans, ChemSystemsChem 8 (2026).","apa":"Lopez‐Acosta, A., Valera, J. S., Klajn, R., &#38; Hermans, T. M. (2026). Photoacid‐mediated controllable gelation in a chemical reaction cycle. <i>ChemSystemsChem</i>. Wiley. <a href=\"https://doi.org/10.1002/syst.70037\">https://doi.org/10.1002/syst.70037</a>","ieee":"A. Lopez‐Acosta, J. S. Valera, R. Klajn, and T. M. Hermans, “Photoacid‐mediated controllable gelation in a chemical reaction cycle,” <i>ChemSystemsChem</i>, vol. 8, no. 3. Wiley, 2026.","ama":"Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. Photoacid‐mediated controllable gelation in a chemical reaction cycle. <i>ChemSystemsChem</i>. 2026;8(3). doi:<a href=\"https://doi.org/10.1002/syst.70037\">10.1002/syst.70037</a>","mla":"Lopez‐Acosta, Alvaro, et al. “Photoacid‐mediated Controllable Gelation in a Chemical Reaction Cycle.” <i>ChemSystemsChem</i>, vol. 8, no. 3, e70037, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/syst.70037\">10.1002/syst.70037</a>."},"publisher":"Wiley","language":[{"iso":"eng"}],"file":[{"file_name":"2026_ChemSystemsChem_LopezAcosta.pdf","date_created":"2026-05-18T06:29:57Z","file_size":1118636,"checksum":"c51e985ac2f2cefb273fdf2cc6ab87e4","file_id":"21887","creator":"dernst","content_type":"application/pdf","relation":"main_file","date_updated":"2026-05-18T06:29:57Z","access_level":"open_access","success":1}],"title":"Photoacid‐mediated controllable gelation in a chemical reaction cycle","author":[{"last_name":"Lopez‐Acosta","first_name":"Alvaro","full_name":"Lopez‐Acosta, Alvaro"},{"last_name":"Valera","first_name":"Jorge S.","full_name":"Valera, Jorge S."},{"full_name":"Klajn, Rafal","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","first_name":"Rafal","last_name":"Klajn"},{"full_name":"Hermans, Thomas M.","last_name":"Hermans","first_name":"Thomas M."}],"type":"journal_article","has_accepted_license":"1","date_published":"2026-04-06T00:00:00Z","ddc":["540"],"publication":"ChemSystemsChem","publication_identifier":{"eissn":["2570-4206"]},"quality_controlled":"1","article_processing_charge":"Yes (in subscription journal)"},{"issue":"4","PlanS_conform":"1","oa":1,"file_date_updated":"2026-05-18T07:48:45Z","keyword":["classic genetics","quantitative genetics","genotype–phenotype map"],"status":"public","publication_status":"published","day":"01","doi":"10.1093/genetics/iyag024","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"NiBa"}],"pmid":1,"oa_version":"Published Version","OA_type":"hybrid","article_number":"iyag024","abstract":[{"lang":"eng","text":"The long-standing notion that genotypes map to phenotypes through simple one gene–one trait relationships continues to shape both research in the life sciences and public understanding, with implications for policy and funding priorities. Yet this paradigm is increasingly recognized as inadequate for explaining continuous phenotypic variation and the complex genetic architectures of the genotype–phenotype map. Modern genetics emerged from the early 20th-century synthesis of Mendelian and biometric schools of heredity, with R.A. Fisher demonstrating early on how multiple discrete loci could collectively produce continuous variation. Despite this fundamental insight, Mendelism—with its focus on single genes and standardized genetic backgrounds—became the dominant framework, shaping current genetics research and molecular biology as well as science education. The advent of large-scale genomic data has revealed yet again the limitations of this reductionist approach. Evidence from quantitative genetics now shows that most phenotypes arise from complex networks of many interdependent genes and their dynamic responses to environmental perturbations. Here we trace the historical roots of how Mendelian classical genetics departed from the biometric school to create the current predominant paradigm in genetics, despite fundamentally unresolved issues. Moving on from this one-sided paradigm will require systematic development of integrative, evolutionarily grounded experimental approaches that better capture the multigenic and context-dependent nature of inheritance. Achieving such an extended perspective will require methodological innovation, including advances in large-scale (e.g. automated) phenotyping. Dedicated research programs will be necessary to advance a new era of genetic research into the complex mechanisms underlying phenotypic variation."}],"volume":232,"date_created":"2026-05-07T08:53:40Z","article_type":"original","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"pmid":["41701356"]},"scopus_import":"1","intvolume":"       232","acknowledgement":"We thank a variety of further colleagues for the many inspiring discussions on the nature of heredity, especially the workshops in Berlin. Special thanks also to the Stellenbosch Institute for Advanced Studies (STIAS) to provide DT the leisure and freedom to write up the first version of this perspective. Thanks also to three reviewers who have helped to improve the manuscript. Two dedicated symposia on the topic were funded by the Max-Planck Society.","OA_place":"publisher","year":"2026","month":"04","_id":"21841","date_updated":"2026-05-18T07:51:26Z","citation":{"mla":"Tautz, Diethard, et al. “Beyond Mendel: A Call to Revisit the Genotype–Phenotype Map through New Experimental Paradigms.” <i>Genetics</i>, vol. 232, no. 4, iyag024, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/genetics/iyag024\">10.1093/genetics/iyag024</a>.","ama":"Tautz D, Pallares LF, Andersson L, et al. Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental paradigms. <i>Genetics</i>. 2026;232(4). doi:<a href=\"https://doi.org/10.1093/genetics/iyag024\">10.1093/genetics/iyag024</a>","ieee":"D. Tautz <i>et al.</i>, “Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental paradigms,” <i>Genetics</i>, vol. 232, no. 4. Oxford University Press, 2026.","apa":"Tautz, D., Pallares, L. F., Andersson, L., Barghi, N., Barton, N. H., Bay, R., … Gibson, G. (2026). Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental paradigms. <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyag024\">https://doi.org/10.1093/genetics/iyag024</a>","short":"D. Tautz, L.F. Pallares, L. Andersson, N. Barghi, N.H. Barton, R. Bay, Y.F. Chan, A. Hancock, T.S. Kaiser, D. Koenig, Z. Kontarakis, M. Liedvogel, J. de Meaux, M. Nordborg, A.A. Palmer, M. Purugganan, C. Schlötterer, K. Schmid, D.Y.R. Stainier, D. Weigel, J.B.W. Wolf, D. Ebert, G. Gibson, Genetics 232 (2026).","ista":"Tautz D, Pallares LF, Andersson L, Barghi N, Barton NH, Bay R, Chan YF, Hancock A, Kaiser TS, Koenig D, Kontarakis Z, Liedvogel M, de Meaux J, Nordborg M, Palmer AA, Purugganan M, Schlötterer C, Schmid K, Stainier DYR, Weigel D, Wolf JBW, Ebert D, Gibson G. 2026. Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental paradigms. Genetics. 232(4), iyag024.","chicago":"Tautz, Diethard, Luisa F Pallares, Leif Andersson, Neda Barghi, Nicholas H Barton, Rachael Bay, Yingguang Frank Chan, et al. “Beyond Mendel: A Call to Revisit the Genotype–Phenotype Map through New Experimental Paradigms.” <i>Genetics</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/genetics/iyag024\">https://doi.org/10.1093/genetics/iyag024</a>."},"publisher":"Oxford University Press","language":[{"iso":"eng"}],"file":[{"checksum":"5a862c539f9dec4511277ad8927c549c","file_size":542844,"date_created":"2026-05-18T07:48:45Z","file_name":"2026_Genetics_Tautz.pdf","creator":"dernst","file_id":"21890","relation":"main_file","content_type":"application/pdf","success":1,"access_level":"open_access","date_updated":"2026-05-18T07:48:45Z"}],"title":"Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental paradigms","author":[{"full_name":"Tautz, Diethard","last_name":"Tautz","first_name":"Diethard"},{"first_name":"Luisa F","last_name":"Pallares","full_name":"Pallares, Luisa F"},{"full_name":"Andersson, Leif","first_name":"Leif","last_name":"Andersson"},{"full_name":"Barghi, Neda","first_name":"Neda","last_name":"Barghi"},{"full_name":"Barton, Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","orcid":"0000-0002-8548-5240"},{"first_name":"Rachael","last_name":"Bay","full_name":"Bay, Rachael"},{"last_name":"Chan","first_name":"Yingguang Frank","full_name":"Chan, Yingguang Frank"},{"first_name":"Angela","last_name":"Hancock","full_name":"Hancock, Angela"},{"last_name":"Kaiser","first_name":"Tobias S","full_name":"Kaiser, Tobias S"},{"first_name":"Daniel","last_name":"Koenig","full_name":"Koenig, Daniel"},{"first_name":"Zacharias","last_name":"Kontarakis","full_name":"Kontarakis, Zacharias"},{"first_name":"Miriam","last_name":"Liedvogel","full_name":"Liedvogel, Miriam"},{"full_name":"de Meaux, Juliette","first_name":"Juliette","last_name":"de Meaux"},{"full_name":"Nordborg, Magnus","last_name":"Nordborg","first_name":"Magnus"},{"last_name":"Palmer","first_name":"Abraham A","full_name":"Palmer, Abraham A"},{"first_name":"Michael","last_name":"Purugganan","full_name":"Purugganan, Michael"},{"full_name":"Schlötterer, Christian","first_name":"Christian","last_name":"Schlötterer"},{"full_name":"Schmid, Karl","last_name":"Schmid","first_name":"Karl"},{"first_name":"Didier Y R","last_name":"Stainier","full_name":"Stainier, Didier Y R"},{"first_name":"Detlef","last_name":"Weigel","full_name":"Weigel, Detlef"},{"full_name":"Wolf, Jochen B W","first_name":"Jochen B W","last_name":"Wolf"},{"last_name":"Ebert","first_name":"Dieter","full_name":"Ebert, Dieter"},{"last_name":"Gibson","first_name":"Greg","full_name":"Gibson, Greg"}],"type":"journal_article","has_accepted_license":"1","date_published":"2026-04-01T00:00:00Z","ddc":["570"],"publication":"Genetics","publication_identifier":{"eissn":["1943-2631"]},"quality_controlled":"1","article_processing_charge":"Yes (in subscription journal)"},{"file":[{"access_level":"open_access","date_updated":"2026-05-18T08:17:26Z","success":1,"content_type":"application/pdf","relation":"main_file","file_id":"21891","creator":"dernst","file_name":"2026_AstrophysicalJourn_Wang.pdf","file_size":2584417,"checksum":"ee9ebc8ae2304fec04f24b82ebaac8bc","date_created":"2026-05-18T08:17:26Z"}],"month":"05","_id":"21882","citation":{"apa":"Wang, B., Leja, J., Katz, H., Inayoshi, K., Cleri, N. J., De Graaff, A., … Nelson, E. J. (2026). The missing hard photons of Little Red Dots: Their incident ionizing spectra resemble massive stars. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae5bab\">https://doi.org/10.3847/1538-4357/ae5bab</a>","short":"B. Wang, J. Leja, H. Katz, K. Inayoshi, N.J. Cleri, A. De Graaff, R.E. Hviding, P. Van Dokkum, J.E. Greene, I. Labbé, J.J. Matthee, I. Mcconachie, R.P. Naidu, E.J. Nelson, The Astrophysical Journal 1003 (2026).","ista":"Wang B, Leja J, Katz H, Inayoshi K, Cleri NJ, De Graaff A, Hviding RE, Van Dokkum P, Greene JE, Labbé I, Matthee JJ, Mcconachie I, Naidu RP, Nelson EJ. 2026. The missing hard photons of Little Red Dots: Their incident ionizing spectra resemble massive stars. The Astrophysical Journal. 1003(1), 10.","ama":"Wang B, Leja J, Katz H, et al. The missing hard photons of Little Red Dots: Their incident ionizing spectra resemble massive stars. <i>The Astrophysical Journal</i>. 2026;1003(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae5bab\">10.3847/1538-4357/ae5bab</a>","mla":"Wang, Bingjie, et al. “The Missing Hard Photons of Little Red Dots: Their Incident Ionizing Spectra Resemble Massive Stars.” <i>The Astrophysical Journal</i>, vol. 1003, no. 1, 10, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae5bab\">10.3847/1538-4357/ae5bab</a>.","ieee":"B. Wang <i>et al.</i>, “The missing hard photons of Little Red Dots: Their incident ionizing spectra resemble massive stars,” <i>The Astrophysical Journal</i>, vol. 1003, no. 1. IOP Publishing, 2026.","chicago":"Wang, Bingjie, Joel Leja, Harley Katz, Kohei Inayoshi, Nikko J. Cleri, Anna De Graaff, Raphael E. Hviding, et al. “The Missing Hard Photons of Little Red Dots: Their Incident Ionizing Spectra Resemble Massive Stars.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae5bab\">https://doi.org/10.3847/1538-4357/ae5bab</a>."},"date_updated":"2026-05-18T08:18:39Z","publisher":"IOP Publishing","language":[{"iso":"eng"}],"year":"2026","acknowledgement":"B.W. thanks Michael Eracleous for valuable discussions. B.W. and J.L. acknowledge support from JWST-GO-04233.009. B.W. also acknowledges support provided by NASA through Hubble Fellowship grant HST-HF2-51592.001 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., for NASA, under the contract NAS 5-26555. K.I. acknowledges support from the National Natural Science Foundation of China (12573015, W2532003), the Beijing Natural Science Foundation (IS25003), and the China Manned Space Program (CMS-CSST-2025-A09). R.E.H. acknowledges support by the German Aerospace Center (DLR) and the Federal Ministry for Economic Affairs and Energy (BMWi) through program 50OR2403 “RUBIES.”\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program # 1433, 2561, 4106, 4233, 5224, 6585. The specific observations analyzed can be accessed via DOI: 10.17909/9hpc-nc45. Computations for this research were performed on the Pennsylvania State University’s Institute for Computational and Data Sciences’ Roar supercomputer; and on computational resources managed and supported by Princeton Research Computing, a consortium of groups including the Princeton Institute for Computational Science and Engineering (PICSciE) and Research Computing at Princeton University. Some of the stellar spectra are retrieved from the POLLUX database (pollux.oreme.org) operated at LUPM (Université de Montpellier—CNRS, France) with the support of the PNPS and INSU. This publication made use of the NASA Astrophysical Data System for bibliographic information.","OA_place":"publisher","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"quality_controlled":"1","article_processing_charge":"Yes","ddc":["520"],"publication":"The Astrophysical Journal","type":"journal_article","has_accepted_license":"1","date_published":"2026-05-01T00:00:00Z","DOAJ_listed":"1","title":"The missing hard photons of Little Red Dots: Their incident ionizing spectra resemble massive stars","author":[{"last_name":"Wang","first_name":"Bingjie","full_name":"Wang, Bingjie"},{"first_name":"Joel","last_name":"Leja","full_name":"Leja, Joel"},{"full_name":"Katz, Harley","first_name":"Harley","last_name":"Katz"},{"last_name":"Inayoshi","first_name":"Kohei","full_name":"Inayoshi, Kohei"},{"last_name":"Cleri","first_name":"Nikko J.","full_name":"Cleri, Nikko J."},{"full_name":"De Graaff, Anna","last_name":"De Graaff","first_name":"Anna"},{"full_name":"Hviding, Raphael E.","last_name":"Hviding","first_name":"Raphael E."},{"full_name":"Van Dokkum, Pieter","last_name":"Van Dokkum","first_name":"Pieter"},{"full_name":"Greene, Jenny E.","last_name":"Greene","first_name":"Jenny E."},{"first_name":"Ivo","last_name":"Labbé","full_name":"Labbé, Ivo"},{"orcid":"0000-0003-2871-127X","last_name":"Matthee","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J"},{"full_name":"Mcconachie, Ian","first_name":"Ian","last_name":"Mcconachie"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"full_name":"Nelson, Erica J.","last_name":"Nelson","first_name":"Erica J."}],"arxiv":1,"day":"01","doi":"10.3847/1538-4357/ae5bab","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"JoMa"}],"status":"public","publication_status":"published","oa":1,"file_date_updated":"2026-05-18T08:17:26Z","issue":"1","PlanS_conform":"1","intvolume":"      1003","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"arxiv":["2508.18358"]},"scopus_import":"1","article_number":"10","abstract":[{"lang":"eng","text":"The nature of little red dots (LRDs) has largely been investigated through their continuum emission, with lines assumed to arise from a broad-line region. In this paper, we instead use recombination lines to infer the intrinsic properties of the central engine. Our analysis first reveals a tension between the ionizing properties implied from Hα and He ii λ4686. The high Hα EWs require copious H-ionizing photons, more than the bluest active galactic nucleus (AGN) ionizing spectra can provide. In contrast, He ii emission is marginally detected, and its low EW is, at most, consistent with the softest AGN spectra. The low He ii/Hβ (∼10−2, <20×  local AGN median) further points to an unusually soft ionizing spectrum. We extend our analysis to dense gas envelopes (quasi-star/black-hole star) and find that hydrogen recombination lines become optically thick and lose diagnostic power, but He ii remains optically thin and a robust tracer. Photoionization modeling with Cloudy rules out standard AGN accretion disk spectra. Alternative explanations include exotic AGN with red rest-optical emission, high average optical depth (>10) from gas/dust, and soft ionizing spectra with abundant H-ionizing photons, consistent with, e.g., a cold accretion disk or a composite of AGN and stars. The latter is an intriguing scenario since high hydrogen densities are highly conducive for star formation, and nuclear star clusters are found in the vicinity of local massive black holes. While previous studies have mostly focused on features dominated by the absorbing hydrogen cloud, the He ii-based diagnostic proposed here represents a crucial step toward understanding the central engine of LRDs."}],"date_created":"2026-05-17T22:02:10Z","volume":1003,"article_type":"original","oa_version":"Published Version","OA_type":"gold"},{"article_processing_charge":"Yes","quality_controlled":"1","publication_identifier":{"eissn":["1077-8926"]},"publication":"Electronic Journal of Combinatorics","ddc":["510"],"DOAJ_listed":"1","date_published":"2026-05-08T00:00:00Z","type":"journal_article","has_accepted_license":"1","arxiv":1,"ec_funded":1,"author":[{"first_name":"Patryk","last_name":"Morawski","full_name":"Morawski, Patryk"},{"full_name":"Petrova, Kalina H","last_name":"Petrova","first_name":"Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381"}],"title":"Randomly perturbed digraphs also have bounded-degree spanning trees","file":[{"date_updated":"2026-05-18T08:46:26Z","access_level":"open_access","success":1,"content_type":"application/pdf","relation":"main_file","file_id":"21893","creator":"dernst","file_name":"2026_ElectrJournCombinatorics_Morawski.pdf","checksum":"9e8402cb2e8870ba7ded9ae7b308201a","file_size":399969,"date_created":"2026-05-18T08:46:26Z"}],"language":[{"iso":"eng"}],"corr_author":"1","publisher":"Electronic Journal of Combinatorics","date_updated":"2026-05-18T08:50:18Z","_id":"21884","citation":{"chicago":"Morawski, Patryk, and Kalina H Petrova. “Randomly Perturbed Digraphs Also Have Bounded-Degree Spanning Trees.” <i>Electronic Journal of Combinatorics</i>. Electronic Journal of Combinatorics, 2026. <a href=\"https://doi.org/10.37236/13316\">https://doi.org/10.37236/13316</a>.","ista":"Morawski P, Petrova KH. 2026. Randomly perturbed digraphs also have bounded-degree spanning trees. Electronic Journal of Combinatorics. 33(2), P2.24.","short":"P. Morawski, K.H. Petrova, Electronic Journal of Combinatorics 33 (2026).","apa":"Morawski, P., &#38; Petrova, K. H. (2026). Randomly perturbed digraphs also have bounded-degree spanning trees. <i>Electronic Journal of Combinatorics</i>. Electronic Journal of Combinatorics. <a href=\"https://doi.org/10.37236/13316\">https://doi.org/10.37236/13316</a>","ieee":"P. Morawski and K. H. Petrova, “Randomly perturbed digraphs also have bounded-degree spanning trees,” <i>Electronic Journal of Combinatorics</i>, vol. 33, no. 2. Electronic Journal of Combinatorics, 2026.","mla":"Morawski, Patryk, and Kalina H. Petrova. “Randomly Perturbed Digraphs Also Have Bounded-Degree Spanning Trees.” <i>Electronic Journal of Combinatorics</i>, vol. 33, no. 2, P2.24, Electronic Journal of Combinatorics, 2026, doi:<a href=\"https://doi.org/10.37236/13316\">10.37236/13316</a>.","ama":"Morawski P, Petrova KH. Randomly perturbed digraphs also have bounded-degree spanning trees. <i>Electronic Journal of Combinatorics</i>. 2026;33(2). doi:<a href=\"https://doi.org/10.37236/13316\">10.37236/13316</a>"},"month":"05","year":"2026","acknowledgement":"We thank the anonymous referees for many helpful comments on an earlier version of this\r\narticle. Kalina Petrova was supported by grant no. CRSII5 173721 of the Swiss National\r\nScience Foundation, and by the European Union’s Horizon 2020 research and innovation\r\nprogramme under the Marie Sk lodowska-Curie grant agreement No. 101034413","OA_place":"publisher","intvolume":"        33","scopus_import":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nd/4.0/legalcode","image":"/image/cc_by_nd.png","short":"CC BY-ND (4.0)","name":"Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)"},"external_id":{"arxiv":["2306.14648"]},"article_type":"original","date_created":"2026-05-17T22:02:11Z","volume":33,"abstract":[{"text":"We show that a randomly perturbed digraph, where we start with a dense digraph Dα and add a small number of random edges to it, will typically contain a fixed orientation of a bounded-degree spanning tree. This answers a question posed by Araujo, Balogh, Krueger, Piga and Treglown and generalizes the corresponding result for randomly perturbed graphs by Krivelevich, Kwan and Sudakov. More specifically, we prove that there exists a constant c=c(α,Δ) such that if \r\nT is an oriented tree with maximum degree Δ and Dα is an n-vertex digraph with minimum semidegree αn, then the graph obtained by adding cn uniformly random edges to Dα will contain T with high probability.","lang":"eng"}],"article_number":"P2.24","OA_type":"gold","oa_version":"Published Version","department":[{"_id":"MaKw"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.37236/13316","day":"08","project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"publication_status":"published","status":"public","oa":1,"file_date_updated":"2026-05-18T08:46:26Z","issue":"2"},{"has_accepted_license":"1","type":"journal_article","date_published":"2026-05-09T00:00:00Z","author":[{"id":"3384113A-F248-11E8-B48F-1D18A9856A87","first_name":"Mohammad","last_name":"Goudarzi","full_name":"Goudarzi, Mohammad"},{"full_name":"Schuster, Maximilian","id":"37e65def-d415-11eb-ae59-a7b67be103db","first_name":"Maximilian","last_name":"Schuster"},{"first_name":"Arthur","last_name":"Milberger","full_name":"Milberger, Arthur"},{"first_name":"Manuel","last_name":"Gunkel","full_name":"Gunkel, Manuel"},{"first_name":"Stefan","last_name":"Terjung","full_name":"Terjung, Stefan"},{"id":"2B819732-F248-11E8-B48F-1D18A9856A87","first_name":"Gabriel","last_name":"Krens","full_name":"Krens, Gabriel","orcid":"0000-0003-4761-5996"}],"title":"3D printing in core facilities – Low pain, high gain","quality_controlled":"1","publication_identifier":{"eissn":["1365-2818"],"issn":["0022-2720"]},"article_processing_charge":"Yes (via OA deal)","ddc":["600"],"publication":"Journal of Microscopy","year":"2026","OA_place":"publisher","acknowledgement":"This work was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Imaging & Optics Facility (IOF) and the MiBa Machine Shop. Specifically; Robert Hauschild (IOF), sharing designs, insights and pioneering 3D printing activities at the Imaging and Optics Facility; Bernhard Hochreiter (IOF), for support and testing of anoxic chamber. We also thank Ana Rita Carvalho Faria and Oliver Biehlmaier (Biozentrum University of Basel, Imaging Core Facility) for sharing the design of the adopted power meter.\r\nOpen Access funding provided by Institute of Science and Technology Austria.","citation":{"chicago":"Goudarzi, Mohammad, Maximilian Schuster, Arthur Milberger, Manuel Gunkel, Stefan Terjung, and Gabriel Krens. “3D Printing in Core Facilities – Low Pain, High Gain.” <i>Journal of Microscopy</i>. Wiley, 2026. <a href=\"https://doi.org/10.1111/jmi.70106\">https://doi.org/10.1111/jmi.70106</a>.","ista":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 2026. 3D printing in core facilities – Low pain, high gain. Journal of Microscopy.","short":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, G. Krens, Journal of Microscopy (2026).","apa":"Goudarzi, M., Schuster, M., Milberger, A., Gunkel, M., Terjung, S., &#38; Krens, G. (2026). 3D printing in core facilities – Low pain, high gain. <i>Journal of Microscopy</i>. Wiley. <a href=\"https://doi.org/10.1111/jmi.70106\">https://doi.org/10.1111/jmi.70106</a>","ieee":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, and G. Krens, “3D printing in core facilities – Low pain, high gain,” <i>Journal of Microscopy</i>. Wiley, 2026.","mla":"Goudarzi, Mohammad, et al. “3D Printing in Core Facilities – Low Pain, High Gain.” <i>Journal of Microscopy</i>, Wiley, 2026, doi:<a href=\"https://doi.org/10.1111/jmi.70106\">10.1111/jmi.70106</a>.","ama":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 3D printing in core facilities – Low pain, high gain. <i>Journal of Microscopy</i>. 2026. doi:<a href=\"https://doi.org/10.1111/jmi.70106\">10.1111/jmi.70106</a>"},"_id":"21883","date_updated":"2026-05-18T08:55:42Z","month":"05","language":[{"iso":"eng"}],"corr_author":"1","publisher":"Wiley","abstract":[{"lang":"eng","text":"Three-dimensional (3D) printing has rapidly developed from a niche hobbyist activity into a widely accessible and indispensable technology across multiple scientific disciplines. Within microscopy, optical engineering laboratories and imaging core facilities, 3D printing enables creating customised solutions for sample holders, optical components and everyday laboratory tools that traditionally required specialised machining. By providing rapid prototyping, low-cost production and reproducibility, 3D printing facilitates innovation and efficiency in facility operations. This article provides a perspective on the possibilities, challenges, and practical aspects of implementing 3D printing within microscopy core facilities. Instead of providing technical review about 3D printing, we focus on service organisation, user engagement, resource management and community-driven repositories for design dissemination. Our aim is to share insights with those considering the implementation of 3D printing as a service for developing add-on components to ease the operation of different aspects of the machine-park driven services and those who are managing advanced instrumentation within research groups."}],"article_type":"original","date_created":"2026-05-17T22:02:11Z","oa_version":"Published Version","pmid":1,"OA_type":"hybrid","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"external_id":{"pmid":["42104760"]},"scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1111/jmi.70106","open_access":"1"}],"oa":1,"PlanS_conform":"1","day":"09","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"Bio"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"M-Shop"}],"doi":"10.1111/jmi.70106","status":"public","publication_status":"epub_ahead"}]
