[{"isi":1,"publication":"Annals of Surgical Oncology","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","oa":1,"day":"01","doi":"10.1245/s10434-022-12681-z","date_published":"2023-01-01T00:00:00Z","intvolume":"        30","year":"2023","acknowledgement":"This work was supported by European Commission’s Seventh Framework Programme under Grant Agreement No. 279113 (OCTIPS; www.octips.eu).","publication_identifier":{"eissn":["1534-4681"],"issn":["1068-9265"]},"article_type":"original","title":"ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome, and patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS) consortium","author":[{"first_name":"Jacek","last_name":"Glajzer","full_name":"Glajzer, Jacek"},{"full_name":"Castillo-Tong, Dan Cacsire","last_name":"Castillo-Tong","first_name":"Dan Cacsire"},{"last_name":"Richter","full_name":"Richter, Rolf","first_name":"Rolf"},{"first_name":"Ignace","last_name":"Vergote","full_name":"Vergote, Ignace"},{"first_name":"Hagen","last_name":"Kulbe","full_name":"Kulbe, Hagen"},{"first_name":"Adriaan","full_name":"Vanderstichele, Adriaan","last_name":"Vanderstichele"},{"last_name":"Ruscito","full_name":"Ruscito, Ilary","first_name":"Ilary"},{"first_name":"Fabian","full_name":"Trillsch, Fabian","last_name":"Trillsch"},{"last_name":"Mustea","full_name":"Mustea, Alexander","first_name":"Alexander"},{"first_name":"Caroline","id":"382077BA-F248-11E8-B48F-1D18A9856A87","full_name":"Kreuzinger, Caroline","last_name":"Kreuzinger"},{"last_name":"Gourley","full_name":"Gourley, Charlie","first_name":"Charlie"},{"first_name":"Hani","full_name":"Gabra, Hani","last_name":"Gabra"},{"first_name":"Eliane T.","full_name":"Taube, Eliane T.","last_name":"Taube"},{"first_name":"Oliver","last_name":"Dorigo","full_name":"Dorigo, Oliver"},{"last_name":"Horst","full_name":"Horst, David","first_name":"David"},{"full_name":"Keunecke, Carlotta","last_name":"Keunecke","first_name":"Carlotta"},{"last_name":"Baum","full_name":"Baum, Joanna","first_name":"Joanna"},{"last_name":"Angelotti","full_name":"Angelotti, Timothy","first_name":"Timothy"},{"first_name":"Jalid","full_name":"Sehouli, Jalid","last_name":"Sehouli"},{"first_name":"Elena Ioana","full_name":"Braicu, Elena Ioana","last_name":"Braicu"}],"date_updated":"2025-04-23T08:43:43Z","related_material":{"record":[{"status":"public","id":"12205","relation":"other"}]},"page":"46-47","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"No","oa_version":"Published Version","keyword":["Oncology","Surgery"],"volume":30,"department":[{"_id":"JoDa"}],"publisher":"Springer Nature","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1245/s10434-022-12681-z"}],"citation":{"short":"J. Glajzer, D.C. Castillo-Tong, R. Richter, I. Vergote, H. Kulbe, A. Vanderstichele, I. Ruscito, F. Trillsch, A. Mustea, C. Kreuzinger, C. Gourley, H. Gabra, E.T. Taube, O. Dorigo, D. Horst, C. Keunecke, J. Baum, T. Angelotti, J. Sehouli, E.I. Braicu, Annals of Surgical Oncology 30 (2023) 46–47.","apa":"Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele, A., … Braicu, E. I. (2023). ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome, and patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. Springer Nature. <a href=\"https://doi.org/10.1245/s10434-022-12681-z\">https://doi.org/10.1245/s10434-022-12681-z</a>","ama":"Glajzer J, Castillo-Tong DC, Richter R, et al. ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome, and patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. 2023;30:46-47. doi:<a href=\"https://doi.org/10.1245/s10434-022-12681-z\">10.1245/s10434-022-12681-z</a>","ieee":"J. Glajzer <i>et al.</i>, “ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome, and patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS) consortium,” <i>Annals of Surgical Oncology</i>, vol. 30. Springer Nature, pp. 46–47, 2023.","mla":"Glajzer, Jacek, et al. “ASO Visual Abstract: Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy—Innovative Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>, vol. 30, Springer Nature, 2023, pp. 46–47, doi:<a href=\"https://doi.org/10.1245/s10434-022-12681-z\">10.1245/s10434-022-12681-z</a>.","chicago":"Glajzer, Jacek, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote, Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, et al. “ASO Visual Abstract: Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy—Innovative Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1245/s10434-022-12681-z\">https://doi.org/10.1245/s10434-022-12681-z</a>.","ista":"Glajzer J, Castillo-Tong DC, Richter R, Vergote I, Kulbe H, Vanderstichele A, Ruscito I, Trillsch F, Mustea A, Kreuzinger C, Gourley C, Gabra H, Taube ET, Dorigo O, Horst D, Keunecke C, Baum J, Angelotti T, Sehouli J, Braicu EI. 2023. ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome, and patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS) consortium. Annals of Surgical Oncology. 30, 46–47."},"type":"journal_article","quality_controlled":"1","_id":"12115","month":"01","scopus_import":"1","publication_status":"published","date_created":"2023-01-12T11:56:22Z","external_id":{"isi":["000879151800001"]}},{"citation":{"short":"P. Zeller, J. Yeung, H. Viñas Gaza, B.A. de Barbanson, V. Bhardwaj, M. Florescu, R. van der Linden, A. van Oudenaarden, Nature Genetics 55 (2023) 333–345.","apa":"Zeller, P., Yeung, J., Viñas Gaza, H., de Barbanson, B. A., Bhardwaj, V., Florescu, M., … van Oudenaarden, A. (2023). Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41588-022-01260-3\">https://doi.org/10.1038/s41588-022-01260-3</a>","ama":"Zeller P, Yeung J, Viñas Gaza H, et al. Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. 2023;55:333-345. doi:<a href=\"https://doi.org/10.1038/s41588-022-01260-3\">10.1038/s41588-022-01260-3</a>","ieee":"P. Zeller <i>et al.</i>, “Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis,” <i>Nature Genetics</i>, vol. 55. Springer Nature, pp. 333–345, 2023.","mla":"Zeller, Peter, et al. “Single-Cell SortChIC Identifies Hierarchical Chromatin Dynamics during Hematopoiesis.” <i>Nature Genetics</i>, vol. 55, Springer Nature, 2023, pp. 333–45, doi:<a href=\"https://doi.org/10.1038/s41588-022-01260-3\">10.1038/s41588-022-01260-3</a>.","chicago":"Zeller, Peter, Jake Yeung, Helena Viñas Gaza, Buys Anton de Barbanson, Vivek Bhardwaj, Maria Florescu, Reinier van der Linden, and Alexander van Oudenaarden. “Single-Cell SortChIC Identifies Hierarchical Chromatin Dynamics during Hematopoiesis.” <i>Nature Genetics</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s41588-022-01260-3\">https://doi.org/10.1038/s41588-022-01260-3</a>.","ista":"Zeller P, Yeung J, Viñas Gaza H, de Barbanson BA, Bhardwaj V, Florescu M, van der Linden R, van Oudenaarden A. 2023. Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis. Nature Genetics. 55, 333–345."},"pmid":1,"abstract":[{"text":"Post-translational histone modifications modulate chromatin activity to affect gene expression. How chromatin states underlie lineage choice in single cells is relatively unexplored. We develop sort-assisted single-cell chromatin immunocleavage (sortChIC) and map active (H3K4me1 and H3K4me3) and repressive (H3K27me3 and H3K9me3) histone modifications in the mouse bone marrow. During differentiation, hematopoietic stem and progenitor cells (HSPCs) acquire active chromatin states mediated by cell-type-specifying transcription factors, which are unique for each lineage. By contrast, most alterations in repressive marks during differentiation occur independent of the final cell type. Chromatin trajectory analysis shows that lineage choice at the chromatin level occurs at the progenitor stage. Joint profiling of H3K4me1 and H3K9me3 demonstrates that cell types within the myeloid lineage have distinct active chromatin but share similar myeloid-specific heterochromatin states. This implies a hierarchical regulation of chromatin during hematopoiesis: heterochromatin dynamics distinguish differentiation trajectories and lineages, while euchromatin dynamics reflect cell types within lineages.","lang":"eng"}],"type":"journal_article","quality_controlled":"1","publisher":"Springer Nature","volume":55,"department":[{"_id":"ScienComp"}],"external_id":{"pmid":["36539617"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","date_created":"2023-01-12T12:09:09Z","month":"02","scopus_import":"1","_id":"12158","year":"2023","acknowledgement":"We thank A. Giladi for sharing mRNA abundance tables of cell types together with J. van den Berg for critical reading of the manuscript. We thank M. Bartosovic for sharing method comparison data. pK19pA-MN was a gift from Ulrich Laemmli (Addgene plasmid 86973, http://n2t.net/addgene:86973; RRID:Addgene_86973). Figure 8 is adopted from Hematopoiesis (human) diagram by A. Rad and M. Häggström under CC-BY-SA 3.0 license. This work was supported by European Research Council Advanced under grant ERC-AdG 742225-IntScOmics and Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) TOP award NWO-CW 714.016.001. The SNF (P2BSP3-174991), HFSP (LT000209/2018-L) and Marie Skłodowska-Curie Actions (798573) supported P.Z. The SNF (P2ELP3_184488) and HFSP (LT000097/2019-L) supported J.Y. and the EMBO LTF (ALTF 1197–2019) supported V.B. This work is part of the Oncode Institute, which is partly financed by the Dutch Cancer Society. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.","publication_identifier":{"issn":["1061-4036"],"eissn":["1546-1718"]},"article_type":"review","oa":1,"file":[{"file_id":"12688","date_updated":"2023-02-27T07:46:45Z","relation":"main_file","content_type":"application/pdf","checksum":"6fdb8e34fbeea63edd0f2c6c2cc5823e","date_created":"2023-02-27T07:46:45Z","file_name":"2023_NatureGenetics_Zeller.pdf","success":1,"file_size":21484855,"creator":"dernst","access_level":"open_access"}],"day":"01","doi":"10.1038/s41588-022-01260-3","date_published":"2023-02-01T00:00:00Z","intvolume":"        55","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570","000"],"publication":"Nature Genetics","keyword":["Genetics"],"oa_version":"Published Version","language":[{"iso":"eng"}],"status":"public","has_accepted_license":"1","article_processing_charge":"No","file_date_updated":"2023-02-27T07:46:45Z","author":[{"first_name":"Peter","last_name":"Zeller","full_name":"Zeller, Peter"},{"first_name":"Jake","orcid":"0000-0003-1732-1559","id":"123012b2-db30-11eb-b4d8-a35840c0551b","full_name":"Yeung, Jake","last_name":"Yeung"},{"first_name":"Helena","last_name":"Viñas Gaza","full_name":"Viñas Gaza, Helena"},{"first_name":"Buys Anton","last_name":"de Barbanson","full_name":"de Barbanson, Buys Anton"},{"last_name":"Bhardwaj","full_name":"Bhardwaj, Vivek","first_name":"Vivek"},{"first_name":"Maria","last_name":"Florescu","full_name":"Florescu, Maria"},{"full_name":"van der Linden, Reinier","last_name":"van der Linden","first_name":"Reinier"},{"first_name":"Alexander","full_name":"van Oudenaarden, Alexander","last_name":"van Oudenaarden"}],"title":"Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis","date_updated":"2025-04-23T08:45:00Z","page":"333-345"},{"_id":"12162","month":"12","scopus_import":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","date_created":"2023-01-12T12:09:47Z","external_id":{"pmid":["36470715"],"isi":["001053522200001"]},"volume":"150-151","department":[{"_id":"EdHa"}],"corr_author":"1","publisher":"Elsevier","citation":{"chicago":"Corominas-Murtra, Bernat, and Edouard B Hannezo. “Modelling the Dynamics of Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.semcdb.2022.11.005\">https://doi.org/10.1016/j.semcdb.2022.11.005</a>.","ista":"Corominas-Murtra B, Hannezo EB. 2023. Modelling the dynamics of mammalian gut homeostasis. Seminars in Cell &#38; Developmental Biology. 150–151, 58–65.","mla":"Corominas-Murtra, Bernat, and Edouard B. Hannezo. “Modelling the Dynamics of Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>, vol. 150–151, Elsevier, 2023, pp. 58–65, doi:<a href=\"https://doi.org/10.1016/j.semcdb.2022.11.005\">10.1016/j.semcdb.2022.11.005</a>.","ieee":"B. Corominas-Murtra and E. B. Hannezo, “Modelling the dynamics of mammalian gut homeostasis,” <i>Seminars in Cell &#38; Developmental Biology</i>, vol. 150–151. Elsevier, pp. 58–65, 2023.","ama":"Corominas-Murtra B, Hannezo EB. Modelling the dynamics of mammalian gut homeostasis. <i>Seminars in Cell &#38; Developmental Biology</i>. 2023;150-151:58-65. doi:<a href=\"https://doi.org/10.1016/j.semcdb.2022.11.005\">10.1016/j.semcdb.2022.11.005</a>","apa":"Corominas-Murtra, B., &#38; Hannezo, E. B. (2023). Modelling the dynamics of mammalian gut homeostasis. <i>Seminars in Cell &#38; Developmental Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.semcdb.2022.11.005\">https://doi.org/10.1016/j.semcdb.2022.11.005</a>","short":"B. Corominas-Murtra, E.B. Hannezo, Seminars in Cell &#38; Developmental Biology 150–151 (2023) 58–65."},"abstract":[{"lang":"eng","text":"Homeostatic balance in the intestinal epithelium relies on a fast cellular turnover, which is coordinated by an intricate interplay between biochemical signalling, mechanical forces and organ geometry. We review recent modelling approaches that have been developed to understand different facets of this remarkable homeostatic equilibrium. Existing models offer different, albeit complementary, perspectives on the problem. First, biomechanical models aim to explain the local and global mechanical stresses driving cell renewal as well as tissue shape maintenance. Second, compartmental models provide insights into the conditions necessary to keep a constant flow of cells with well-defined ratios of cell types, and how perturbations can lead to an unbalance of relative compartment sizes. A third family of models address, at the cellular level, the nature and regulation of stem fate choices that are necessary to fuel cellular turnover. We also review how these different approaches are starting to be integrated together across scales, to provide quantitative predictions and new conceptual frameworks to think about the dynamics of cell renewal in complex tissues."}],"type":"journal_article","pmid":1,"quality_controlled":"1","author":[{"orcid":"0000-0001-9806-5643","last_name":"Corominas-Murtra","full_name":"Corominas-Murtra, Bernat","id":"43BE2298-F248-11E8-B48F-1D18A9856A87","first_name":"Bernat"},{"orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","last_name":"Hannezo","first_name":"Edouard B"}],"title":"Modelling the dynamics of mammalian gut homeostasis","page":"58-65","date_updated":"2025-04-14T07:52:27Z","language":[{"iso":"eng"}],"status":"public","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","file_date_updated":"2024-01-08T10:16:04Z","oa_version":"Published Version","keyword":["Cell Biology","Developmental Biology"],"isi":1,"publication":"Seminars in Cell & Developmental Biology","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","grant_number":"851288","_id":"05943252-7A3F-11EA-A408-12923DDC885E","name":"Design Principles of Branching Morphogenesis"}],"ddc":["570"],"oa":1,"file":[{"date_created":"2024-01-08T10:16:04Z","file_name":"2023_SeminarsCellDevBiology_CorominasMurtra.pdf","success":1,"creator":"dernst","file_size":1343750,"access_level":"open_access","date_updated":"2024-01-08T10:16:04Z","file_id":"14741","checksum":"c619887cf130f4649bf3035417186004","content_type":"application/pdf","relation":"main_file"}],"day":"02","doi":"10.1016/j.semcdb.2022.11.005","date_published":"2023-12-02T00:00:00Z","year":"2023","publication_identifier":{"issn":["1084-9521"]},"article_type":"review","acknowledgement":"This work received funding from the ERC under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 851288 to E.H.).\r\nB. C-M wants to acknowledge the support of the field of excellence Complexity of Life, in Basic Research and Innovation of the University of Graz.","ec_funded":1},{"quality_controlled":"1","citation":{"short":"M. Loose, A. Auer, G. Brognara, H.R. Budiman, L.M. Kowalski, I. Matijevic, FEBS Letters 597 (2023) 762–777.","mla":"Loose, Martin, et al. “In Vitro Reconstitution of Small GTPase Regulation.” <i>FEBS Letters</i>, vol. 597, no. 6, Wiley, 2023, pp. 762–77, doi:<a href=\"https://doi.org/10.1002/1873-3468.14540\">10.1002/1873-3468.14540</a>.","chicago":"Loose, Martin, Albert Auer, Gabriel Brognara, Hanifatul R Budiman, Lukasz M Kowalski, and Ivana Matijevic. “In Vitro Reconstitution of Small GTPase Regulation.” <i>FEBS Letters</i>. Wiley, 2023. <a href=\"https://doi.org/10.1002/1873-3468.14540\">https://doi.org/10.1002/1873-3468.14540</a>.","ista":"Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. 2023. In vitro reconstitution of small GTPase regulation. FEBS Letters. 597(6), 762–777.","apa":"Loose, M., Auer, A., Brognara, G., Budiman, H. R., Kowalski, L. M., &#38; Matijevic, I. (2023). In vitro reconstitution of small GTPase regulation. <i>FEBS Letters</i>. Wiley. <a href=\"https://doi.org/10.1002/1873-3468.14540\">https://doi.org/10.1002/1873-3468.14540</a>","ama":"Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. In vitro reconstitution of small GTPase regulation. <i>FEBS Letters</i>. 2023;597(6):762-777. doi:<a href=\"https://doi.org/10.1002/1873-3468.14540\">10.1002/1873-3468.14540</a>","ieee":"M. Loose, A. Auer, G. Brognara, H. R. Budiman, L. M. Kowalski, and I. Matijevic, “In vitro reconstitution of small GTPase regulation,” <i>FEBS Letters</i>, vol. 597, no. 6. Wiley, pp. 762–777, 2023."},"type":"journal_article","abstract":[{"lang":"eng","text":"Small GTPases play essential roles in the organization of eukaryotic cells. In recent years, it has become clear that their intracellular functions result from intricate biochemical networks of the GTPase and their regulators that dynamically bind to a membrane surface. Due to the inherent complexities of their interactions, however, revealing the underlying mechanisms of action is often difficult to achieve from in vivo studies. This review summarizes in vitro reconstitution approaches developed to obtain a better mechanistic understanding of how small GTPase activities are regulated in space and time."}],"pmid":1,"corr_author":"1","publisher":"Wiley","department":[{"_id":"MaLo"}],"volume":597,"external_id":{"isi":["000891573000001"],"pmid":["36448231"]},"date_created":"2023-01-12T12:09:58Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"publication_status":"published","issue":"6","scopus_import":"1","month":"03","_id":"12163","publication_identifier":{"issn":["0014-5793"],"eissn":["1873-3468"]},"acknowledgement":"The authors acknowledge support from IST Austria and helpful comments from the anonymous reviewers that helped to improve this manuscript. We apologize to the authors of primary literature and outstanding research not cited here due to space restraints.","article_type":"review","year":"2023","date_published":"2023-03-01T00:00:00Z","intvolume":"       597","oa":1,"file":[{"file_size":3148143,"creator":"dernst","success":1,"date_created":"2023-08-16T08:31:04Z","file_name":"2023_FEBSLetters_Loose.pdf","access_level":"open_access","file_id":"14063","date_updated":"2023-08-16T08:31:04Z","relation":"main_file","checksum":"7492244d3f9c5faa1347ef03f6e5bc84","content_type":"application/pdf"}],"day":"01","doi":"10.1002/1873-3468.14540","ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"publication":"FEBS Letters","keyword":["Cell Biology","Genetics","Molecular Biology","Biochemistry","Structural Biology","Biophysics"],"oa_version":"Published Version","has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","file_date_updated":"2023-08-16T08:31:04Z","language":[{"iso":"eng"}],"status":"public","date_updated":"2024-10-09T21:03:42Z","page":"762-777","title":"In vitro reconstitution of small GTPase regulation","author":[{"first_name":"Martin","orcid":"0000-0001-7309-9724","id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin","last_name":"Loose"},{"first_name":"Albert","full_name":"Auer, Albert","last_name":"Auer","id":"3018E8C2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3580-2906"},{"full_name":"Brognara, Gabriel","last_name":"Brognara","id":"D96FFDA0-A884-11E9-9968-DC26E6697425","first_name":"Gabriel"},{"id":"55380f95-15b2-11ec-abd3-aff8e230696b","full_name":"Budiman, Hanifatul R","last_name":"Budiman","first_name":"Hanifatul R"},{"first_name":"Lukasz M","last_name":"Kowalski","full_name":"Kowalski, Lukasz M","id":"e3a512e2-4bbe-11eb-a68a-e3857a7844c2"},{"full_name":"Matijevic, Ivana","last_name":"Matijevic","id":"83c17ce3-15b2-11ec-abd3-f486545870bd","first_name":"Ivana"}]},{"external_id":{"isi":["000890138700001"]},"date_created":"2023-01-12T12:10:08Z","publication_status":"published","scopus_import":"1","month":"03","_id":"12164","quality_controlled":"1","abstract":[{"text":"A shared-memory counter is a widely-used and well-studied concurrent object. It supports two operations: An Inc operation that increases its value by 1 and a Read operation that returns its current value. In Jayanti et al (SIAM J Comput, 30(2), 2000), Jayanti, Tan and Toueg proved a linear lower bound on the worst-case step complexity of obstruction-free implementations, from read-write registers, of a large class of shared objects that includes counters. The lower bound leaves open the question of finding counter implementations with sub-linear amortized step complexity. In this work, we address this gap. We show that n-process, wait-free and linearizable counters can be implemented from read-write registers with O(log2n) amortized step complexity. This is the first counter algorithm from read-write registers that provides sub-linear amortized step complexity in executions of arbitrary length. Since a logarithmic lower bound on the amortized step complexity of obstruction-free counter implementations exists, our upper bound is within a logarithmic factor of the optimal. The worst-case step complexity of the construction remains linear, which is optimal. This is obtained thanks to a new max register construction with O(logn) amortized step complexity in executions of arbitrary length in which the value stored in the register does not grow too quickly. We then leverage an existing counter algorithm by Aspnes, Attiya and Censor-Hillel [1] in which we “plug” our max register implementation to show that it remains linearizable while achieving O(log2n) amortized step complexity.","lang":"eng"}],"type":"journal_article","citation":{"ieee":"M. A. Baig, D. Hendler, A. Milani, and C. Travers, “Long-lived counters with polylogarithmic amortized step complexity,” <i>Distributed Computing</i>, vol. 36. Springer Nature, pp. 29–43, 2023.","apa":"Baig, M. A., Hendler, D., Milani, A., &#38; Travers, C. (2023). Long-lived counters with polylogarithmic amortized step complexity. <i>Distributed Computing</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00446-022-00439-5\">https://doi.org/10.1007/s00446-022-00439-5</a>","ama":"Baig MA, Hendler D, Milani A, Travers C. Long-lived counters with polylogarithmic amortized step complexity. <i>Distributed Computing</i>. 2023;36:29-43. doi:<a href=\"https://doi.org/10.1007/s00446-022-00439-5\">10.1007/s00446-022-00439-5</a>","ista":"Baig MA, Hendler D, Milani A, Travers C. 2023. Long-lived counters with polylogarithmic amortized step complexity. Distributed Computing. 36, 29–43.","chicago":"Baig, Mirza Ahad, Danny Hendler, Alessia Milani, and Corentin Travers. “Long-Lived Counters with Polylogarithmic Amortized Step Complexity.” <i>Distributed Computing</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/s00446-022-00439-5\">https://doi.org/10.1007/s00446-022-00439-5</a>.","mla":"Baig, Mirza Ahad, et al. “Long-Lived Counters with Polylogarithmic Amortized Step Complexity.” <i>Distributed Computing</i>, vol. 36, Springer Nature, 2023, pp. 29–43, doi:<a href=\"https://doi.org/10.1007/s00446-022-00439-5\">10.1007/s00446-022-00439-5</a>.","short":"M.A. Baig, D. Hendler, A. Milani, C. Travers, Distributed Computing 36 (2023) 29–43."},"main_file_link":[{"open_access":"1","url":"https://drops.dagstuhl.de/opus/volltexte/2019/11310/"}],"publisher":"Springer Nature","department":[{"_id":"KrPi"}],"volume":36,"keyword":["Computational Theory and Mathematics","Computer Networks and Communications","Hardware and Architecture","Theoretical Computer Science"],"oa_version":"Preprint","article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","page":"29-43","date_updated":"2023-08-16T08:39:36Z","title":"Long-lived counters with polylogarithmic amortized step complexity","author":[{"first_name":"Mirza Ahad","id":"3EDE6DE4-AA5A-11E9-986D-341CE6697425","full_name":"Baig, Mirza Ahad","last_name":"Baig"},{"last_name":"Hendler","full_name":"Hendler, Danny","first_name":"Danny"},{"first_name":"Alessia","full_name":"Milani, Alessia","last_name":"Milani"},{"first_name":"Corentin","full_name":"Travers, Corentin","last_name":"Travers"}],"acknowledgement":"A preliminary version of this work appeared in DISC’19. Mirza Ahad Baig, Alessia Milani and Corentin Travers are supported by ANR projects Descartes and FREDDA. Mirza Ahad Baig is supported by UMI Relax. Danny Hendler is supported by the Israel Science Foundation (Grants 380/18 and 1425/22).","publication_identifier":{"issn":["0178-2770"],"eissn":["1432-0452"]},"year":"2023","article_type":"original","intvolume":"        36","date_published":"2023-03-01T00:00:00Z","day":"01","doi":"10.1007/s00446-022-00439-5","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Distributed Computing","isi":1},{"_id":"12165","month":"01","scopus_import":"1","publication_status":"published","date_created":"2023-01-12T12:10:18Z","external_id":{"isi":["000890148700002"]},"volume":5,"department":[{"_id":"BjHo"}],"corr_author":"1","publisher":"Springer Nature","citation":{"short":"B. Hof, Nature Reviews Physics 5 (2023) 62–72.","apa":"Hof, B. (2023). Directed percolation and the transition to turbulence. <i>Nature Reviews Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s42254-022-00539-y\">https://doi.org/10.1038/s42254-022-00539-y</a>","ama":"Hof B. Directed percolation and the transition to turbulence. <i>Nature Reviews Physics</i>. 2023;5:62-72. doi:<a href=\"https://doi.org/10.1038/s42254-022-00539-y\">10.1038/s42254-022-00539-y</a>","ieee":"B. Hof, “Directed percolation and the transition to turbulence,” <i>Nature Reviews Physics</i>, vol. 5. Springer Nature, pp. 62–72, 2023.","ista":"Hof B. 2023. Directed percolation and the transition to turbulence. Nature Reviews Physics. 5, 62–72.","chicago":"Hof, Björn. “Directed Percolation and the Transition to Turbulence.” <i>Nature Reviews Physics</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1038/s42254-022-00539-y\">https://doi.org/10.1038/s42254-022-00539-y</a>.","mla":"Hof, Björn. “Directed Percolation and the Transition to Turbulence.” <i>Nature Reviews Physics</i>, vol. 5, Springer Nature, 2023, pp. 62–72, doi:<a href=\"https://doi.org/10.1038/s42254-022-00539-y\">10.1038/s42254-022-00539-y</a>."},"abstract":[{"text":"It may come as a surprise that a phenomenon as ubiquitous and prominent as the transition from laminar to turbulent flow has resisted combined efforts by physicists, engineers and mathematicians, and remained unresolved for almost one and a half centuries. In recent years, various studies have proposed analogies to directed percolation, a well-known universality class in statistical mechanics, which describes a non-equilibrium phase transition from a fluctuating active phase into an absorbing state. It is this unlikely relation between the multiscale, high-dimensional dynamics that signify the transition process in virtually all flows of practical relevance, and the arguably most basic non-equilibrium phase transition, that so far has mainly been the subject of model studies, which I review in this Perspective.","lang":"eng"}],"type":"journal_article","quality_controlled":"1","author":[{"orcid":"0000-0003-2057-2754","id":"3A374330-F248-11E8-B48F-1D18A9856A87","last_name":"Hof","full_name":"Hof, Björn","first_name":"Björn"}],"title":"Directed percolation and the transition to turbulence","date_updated":"2024-10-09T21:04:02Z","page":"62-72","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"No","oa_version":"None","keyword":["General Physics and Astronomy"],"isi":1,"publication":"Nature Reviews Physics","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","doi":"10.1038/s42254-022-00539-y","day":"01","date_published":"2023-01-01T00:00:00Z","intvolume":"         5","publication_identifier":{"eissn":["2522-5820"]},"year":"2023","article_type":"original"},{"oa_version":"Published Version","keyword":["Genetics","Ecology","Evolution","Behavior and Systematics"],"page":"26-29","date_updated":"2025-04-23T08:44:33Z","title":"Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize","author":[{"first_name":"Anja M","last_name":"Westram","full_name":"Westram, Anja M","id":"3C147470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1050-4969"},{"full_name":"Butlin, Roger","last_name":"Butlin","first_name":"Roger"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","intvolume":"        32","date_published":"2023-01-01T00:00:00Z","doi":"10.1111/mec.16779","day":"01","oa":1,"year":"2023","article_type":"editorial","publication_identifier":{"issn":["0962-1083"],"eissn":["1365-294X"]},"publication":"Molecular Ecology","isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-01-12T12:10:28Z","publication_status":"published","external_id":{"isi":["000892168800001"],"pmid":["36443277"]},"_id":"12166","scopus_import":"1","issue":"1","month":"01","quality_controlled":"1","type":"journal_article","abstract":[{"text":"Kerstin Johannesson is a marine ecologist and evolutionary biologist based at the Tjärnö Marine Laboratory of the University of Gothenburg, which is situated in the beautiful Kosterhavet National Park on the Swedish west coast. Her work, using marine periwinkles (especially Littorina saxatilis and L. fabalis) as main model systems, has made a remarkable contribution to marine evolutionary biology and our understanding of local adaptation and its genetic underpinnings.","lang":"eng"}],"pmid":1,"citation":{"short":"A.M. Westram, R. Butlin, Molecular Ecology 32 (2023) 26–29.","mla":"Westram, Anja M., and Roger Butlin. “Professor Kerstin Johannesson–Winner of the 2022 Molecular Ecology Prize.” <i>Molecular Ecology</i>, vol. 32, no. 1, Wiley, 2023, pp. 26–29, doi:<a href=\"https://doi.org/10.1111/mec.16779\">10.1111/mec.16779</a>.","ista":"Westram AM, Butlin R. 2023. Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize. Molecular Ecology. 32(1), 26–29.","chicago":"Westram, Anja M, and Roger Butlin. “Professor Kerstin Johannesson–Winner of the 2022 Molecular Ecology Prize.” <i>Molecular Ecology</i>. Wiley, 2023. <a href=\"https://doi.org/10.1111/mec.16779\">https://doi.org/10.1111/mec.16779</a>.","apa":"Westram, A. M., &#38; Butlin, R. (2023). Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize. <i>Molecular Ecology</i>. Wiley. <a href=\"https://doi.org/10.1111/mec.16779\">https://doi.org/10.1111/mec.16779</a>","ama":"Westram AM, Butlin R. Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize. <i>Molecular Ecology</i>. 2023;32(1):26-29. doi:<a href=\"https://doi.org/10.1111/mec.16779\">10.1111/mec.16779</a>","ieee":"A. M. Westram and R. Butlin, “Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize,” <i>Molecular Ecology</i>, vol. 32, no. 1. Wiley, pp. 26–29, 2023."},"department":[{"_id":"NiBa"}],"OA_type":"free access","volume":32,"main_file_link":[{"url":"https://doi.org/10.1111/mec.16779","open_access":"1"}],"corr_author":"1","publisher":"Wiley"},{"publication":"Materials Today: Proceedings","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"20","doi":"10.1016/j.matpr.2022.11.037","intvolume":"        78","date_published":"2023-03-20T00:00:00Z","publication_identifier":{"issn":["2214-7853"]},"year":"2023","article_type":"original","author":[{"first_name":"Bushra","last_name":"Khatoon","full_name":"Khatoon, Bushra"},{"first_name":"Shoaib","id":"185a19af-dc7d-11ea-9b2f-8eb2201959e9","last_name":"Kamil","full_name":"Kamil, Shoaib"},{"last_name":"Babu","full_name":"Babu, Hitesh","first_name":"Hitesh"},{"first_name":"M.","last_name":"Siraj Alam","full_name":"Siraj Alam, M."}],"title":"Experimental analysis of Cascade CSTRs with step and pulse inputs","date_updated":"2023-08-16T09:08:11Z","page":"40-47","language":[{"iso":"eng"}],"status":"public","article_processing_charge":"No","oa_version":"None","keyword":["General Medicine"],"volume":78,"department":[{"_id":"BjHo"}],"publisher":"Elsevier","abstract":[{"lang":"eng","text":"In industrial reactors and equipment, non-ideality is quite a common phenomenon rather than an exception. These deviations from ideality impact the process's overall efficiency and the effectiveness of the equipment. To recognize the associated non-ideality, one needs to have enough understanding of the formulation of the equations and in-depth knowledge of the residence time distribution (RTD) data of real reactors. In the current work, step input and pulse input were used to create RTD data for Cascade continuous stirred tank reactors (CSTRs). For the aforementioned configuration, experiments were run at various flow rates to validate the developed characteristic equations. To produce RTD data, distilled water was utilized as the flowing fluid, and NaOH was the tracer substance. The ideal behavior of tracer concentration exits age distribution, and cumulative fraction for each setup and each input was plotted and experimental results were compared with perfect behavior. Deviation of concentration exit age distribution and cumulative fractional distribution from ideal behavior is more in pulse input as compared to a step input. For ideal cases, the exit age distribution curve and cumulative fraction curves are independent of the type of input. But a significant difference was observed for the two cases, which may be due to non-measurable fluctuations in volumetric flow rate, non-achievement of instant injection of tracer in case of pulse input, and slight variations in the sampling period. Further, with increasing flow rate, concentration, exit age, and cumulative fractional curves shifted upward, and this behavior matches with the actual case."}],"type":"journal_article","citation":{"short":"B. Khatoon, S. Kamil, H. Babu, M. Siraj Alam, Materials Today: Proceedings 78 (2023) 40–47.","chicago":"Khatoon, Bushra, Shoaib Kamil, Hitesh Babu, and M. Siraj Alam. “Experimental Analysis of Cascade CSTRs with Step and Pulse Inputs.” <i>Materials Today: Proceedings</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.matpr.2022.11.037\">https://doi.org/10.1016/j.matpr.2022.11.037</a>.","ista":"Khatoon B, Kamil S, Babu H, Siraj Alam M. 2023. Experimental analysis of Cascade CSTRs with step and pulse inputs. Materials Today: Proceedings. 78(Part 1), 40–47.","mla":"Khatoon, Bushra, et al. “Experimental Analysis of Cascade CSTRs with Step and Pulse Inputs.” <i>Materials Today: Proceedings</i>, vol. 78, no. Part 1, Elsevier, 2023, pp. 40–47, doi:<a href=\"https://doi.org/10.1016/j.matpr.2022.11.037\">10.1016/j.matpr.2022.11.037</a>.","ieee":"B. Khatoon, S. Kamil, H. Babu, and M. Siraj Alam, “Experimental analysis of Cascade CSTRs with step and pulse inputs,” <i>Materials Today: Proceedings</i>, vol. 78, no. Part 1. Elsevier, pp. 40–47, 2023.","ama":"Khatoon B, Kamil S, Babu H, Siraj Alam M. Experimental analysis of Cascade CSTRs with step and pulse inputs. <i>Materials Today: Proceedings</i>. 2023;78(Part 1):40-47. doi:<a href=\"https://doi.org/10.1016/j.matpr.2022.11.037\">10.1016/j.matpr.2022.11.037</a>","apa":"Khatoon, B., Kamil, S., Babu, H., &#38; Siraj Alam, M. (2023). Experimental analysis of Cascade CSTRs with step and pulse inputs. <i>Materials Today: Proceedings</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.matpr.2022.11.037\">https://doi.org/10.1016/j.matpr.2022.11.037</a>"},"quality_controlled":"1","_id":"12172","month":"03","scopus_import":"1","issue":"Part 1","publication_status":"published","date_created":"2023-01-12T12:11:26Z"},{"date_created":"2023-01-15T23:00:52Z","publication_status":"published","external_id":{"isi":["000910751800002"],"arxiv":["2205.15284"]},"_id":"12183","scopus_import":"1","month":"05","quality_controlled":"1","abstract":[{"text":"We consider a gas of n bosonic particles confined in a box [−ℓ/2,ℓ/2]3 with Neumann boundary conditions. We prove Bose–Einstein condensation in the Gross–Pitaevskii regime, with an optimal bound on the condensate depletion. Moreover, our lower bound for the ground state energy in a small box [−ℓ/2,ℓ/2]3 implies (via Neumann bracketing) a lower bound for the ground state energy of N bosons in a large box [−L/2,L/2]3 with density ρ=N/L3 in the thermodynamic limit.","lang":"eng"}],"type":"journal_article","citation":{"short":"C. Boccato, R. Seiringer, Annales Henri Poincare 24 (2023) 1505–1560.","mla":"Boccato, Chiara, and Robert Seiringer. “The Bose Gas in a Box with Neumann Boundary Conditions.” <i>Annales Henri Poincare</i>, vol. 24, Springer Nature, 2023, pp. 1505–60, doi:<a href=\"https://doi.org/10.1007/s00023-022-01252-3\">10.1007/s00023-022-01252-3</a>.","ista":"Boccato C, Seiringer R. 2023. The Bose Gas in a box with Neumann boundary conditions. Annales Henri Poincare. 24, 1505–1560.","chicago":"Boccato, Chiara, and Robert Seiringer. “The Bose Gas in a Box with Neumann Boundary Conditions.” <i>Annales Henri Poincare</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/s00023-022-01252-3\">https://doi.org/10.1007/s00023-022-01252-3</a>.","ama":"Boccato C, Seiringer R. The Bose Gas in a box with Neumann boundary conditions. <i>Annales Henri Poincare</i>. 2023;24:1505-1560. doi:<a href=\"https://doi.org/10.1007/s00023-022-01252-3\">10.1007/s00023-022-01252-3</a>","ieee":"C. Boccato and R. Seiringer, “The Bose Gas in a box with Neumann boundary conditions,” <i>Annales Henri Poincare</i>, vol. 24. Springer Nature, pp. 1505–1560, 2023.","apa":"Boccato, C., &#38; Seiringer, R. (2023). The Bose Gas in a box with Neumann boundary conditions. <i>Annales Henri Poincare</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00023-022-01252-3\">https://doi.org/10.1007/s00023-022-01252-3</a>"},"department":[{"_id":"RoSe"}],"volume":24,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2205.15284"}],"publisher":"Springer Nature","corr_author":"1","oa_version":"Preprint","page":"1505-1560","date_updated":"2025-04-14T07:26:59Z","author":[{"id":"342E7E22-F248-11E8-B48F-1D18A9856A87","last_name":"Boccato","full_name":"Boccato, Chiara","first_name":"Chiara"},{"orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","full_name":"Seiringer, Robert","first_name":"Robert"}],"title":"The Bose Gas in a box with Neumann boundary conditions","article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","intvolume":"        24","date_published":"2023-05-01T00:00:00Z","doi":"10.1007/s00023-022-01252-3","day":"01","oa":1,"ec_funded":1,"acknowledgement":"Funding from the European Union’s Horizon 2020 research and innovation programme under the ERC grant agreement No 694227 is gratefully acknowledged.","publication_identifier":{"issn":["1424-0637"]},"year":"2023","article_type":"original","publication":"Annales Henri Poincare","arxiv":1,"isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems","grant_number":"694227"}]},{"quality_controlled":"1","citation":{"apa":"Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele, A., … Braicu, E. I. (2023). Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome and patient survival in primary and recurrent high-grade serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. Springer Nature. <a href=\"https://doi.org/10.1245/s10434-022-12459-3\">https://doi.org/10.1245/s10434-022-12459-3</a>","ieee":"J. Glajzer <i>et al.</i>, “Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome and patient survival in primary and recurrent high-grade serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium,” <i>Annals of Surgical Oncology</i>, vol. 30. Springer Nature, pp. 35–45, 2023.","ama":"Glajzer J, Castillo-Tong DC, Richter R, et al. Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome and patient survival in primary and recurrent high-grade serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. 2023;30:35-45. doi:<a href=\"https://doi.org/10.1245/s10434-022-12459-3\">10.1245/s10434-022-12459-3</a>","ista":"Glajzer J, Castillo-Tong DC, Richter R, Vergote I, Kulbe H, Vanderstichele A, Ruscito I, Trillsch F, Mustea A, Kreuzinger C, Gourley C, Gabra H, Taube ET, Dorigo O, Horst D, Keunecke C, Baum J, Angelotti T, Sehouli J, Braicu EI. 2023. Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome and patient survival in primary and recurrent high-grade serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium. Annals of Surgical Oncology. 30, 35–45.","chicago":"Glajzer, Jacek, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote, Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, et al. “Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>. Springer Nature, 2023. <a href=\"https://doi.org/10.1245/s10434-022-12459-3\">https://doi.org/10.1245/s10434-022-12459-3</a>.","mla":"Glajzer, Jacek, et al. “Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>, vol. 30, Springer Nature, 2023, pp. 35–45, doi:<a href=\"https://doi.org/10.1245/s10434-022-12459-3\">10.1245/s10434-022-12459-3</a>.","short":"J. Glajzer, D.C. Castillo-Tong, R. Richter, I. Vergote, H. Kulbe, A. Vanderstichele, I. Ruscito, F. Trillsch, A. Mustea, C. Kreuzinger, C. Gourley, H. Gabra, E.T. Taube, O. Dorigo, D. Horst, C. Keunecke, J. Baum, T. Angelotti, J. Sehouli, E.I. Braicu, Annals of Surgical Oncology 30 (2023) 35–45."},"abstract":[{"lang":"eng","text":"Background: This study seeks to evaluate the impact of breast cancer (BRCA) gene status on tumor dissemination pattern, surgical outcome and survival in a multicenter cohort of paired primary ovarian cancer (pOC) and recurrent ovarian cancer (rOC).\r\n\r\nPatients and Methods: Medical records and follow-up data from 190 patients were gathered retrospectively. All patients had surgery at pOC and at least one further rOC surgery at four European high-volume centers. Patients were divided into one cohort with confirmed mutation for BRCA1 and/or BRCA2 (BRCAmut) and a second cohort with BRCA wild type or unknown (BRCAwt). Patterns of tumor presentation, surgical outcome and survival data were analyzed between the two groups.\r\n\r\nResults: Patients with BRCAmut disease were on average 4 years younger and had significantly more tumor involvement upon diagnosis. Patients with BRCAmut disease showed higher debulking rates at all stages. Multivariate analysis showed that only patient age had significant predictive value for complete tumor resection in pOC. At rOC, however, only BRCAmut status significantly correlated with optimal debulking. Patients with BRCAmut disease showed significantly prolonged overall survival (OS) by 24.3 months. Progression-free survival (PFS) was prolonged in the BRCAmut group at all stages as well, reaching statistical significance during recurrence.\r\n\r\nConclusions: Patients with BRCAmut disease showed a more aggressive course of disease with earlier onset and more extensive tumor dissemination at pOC. However, surgical outcome and OS were significantly better in patients with BRCAmut disease compared with patients with BRCAwt disease. We therefore propose to consider BRCAmut status in regard to patient selection for cytoreductive surgery, especially in rOC."}],"pmid":1,"type":"journal_article","publisher":"Springer Nature","department":[{"_id":"JoDa"}],"volume":30,"external_id":{"pmid":["36085390"],"isi":["000852125500006"]},"date_created":"2023-01-16T09:44:36Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","scopus_import":"1","month":"01","_id":"12205","article_type":"original","publication_identifier":{"eissn":["1534-4681"],"issn":["1068-9265"]},"year":"2023","acknowledgement":"E.I.B. is a Feodor Lynen fellow of the Humboldt Foundation and a participant of the Charité Clinical Scientist Program funded by the Charité Universitätsmedizin Berlin and the Berlin Institute of Health. This work was supported by European Commission’s Seventh Framework Programme under grant agreement no. 279113 (OCTIPS; www.octips.eu).\r\nOpen Access funding enabled and organized by Projekt DEAL.","date_published":"2023-01-01T00:00:00Z","intvolume":"        30","file":[{"content_type":"application/pdf","checksum":"36a1200e1011f4b2155a8041d0308f34","relation":"main_file","date_updated":"2023-02-02T13:01:20Z","file_id":"12490","access_level":"open_access","creator":"dernst","file_size":365865,"success":1,"date_created":"2023-02-02T13:01:20Z","file_name":"2023_AnnalsSurgicalOncology_Glajzer.pdf"}],"oa":1,"doi":"10.1245/s10434-022-12459-3","day":"01","ddc":["610"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"publication":"Annals of Surgical Oncology","keyword":["Oncology","Surgery"],"oa_version":"Published Version","article_processing_charge":"No","has_accepted_license":"1","file_date_updated":"2023-02-02T13:01:20Z","status":"public","language":[{"iso":"eng"}],"related_material":{"record":[{"relation":"other","id":"12115","status":"public"}]},"date_updated":"2025-04-23T08:43:44Z","page":"35-45","title":"Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome and patient survival in primary and recurrent high-grade serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium","author":[{"full_name":"Glajzer, Jacek","last_name":"Glajzer","first_name":"Jacek"},{"last_name":"Castillo-Tong","full_name":"Castillo-Tong, Dan Cacsire","first_name":"Dan Cacsire"},{"last_name":"Richter","full_name":"Richter, Rolf","first_name":"Rolf"},{"first_name":"Ignace","full_name":"Vergote, Ignace","last_name":"Vergote"},{"last_name":"Kulbe","full_name":"Kulbe, Hagen","first_name":"Hagen"},{"full_name":"Vanderstichele, Adriaan","last_name":"Vanderstichele","first_name":"Adriaan"},{"first_name":"Ilary","last_name":"Ruscito","full_name":"Ruscito, Ilary"},{"first_name":"Fabian","last_name":"Trillsch","full_name":"Trillsch, Fabian"},{"full_name":"Mustea, Alexander","last_name":"Mustea","first_name":"Alexander"},{"id":"382077BA-F248-11E8-B48F-1D18A9856A87","last_name":"Kreuzinger","full_name":"Kreuzinger, Caroline","first_name":"Caroline"},{"first_name":"Charlie","full_name":"Gourley, Charlie","last_name":"Gourley"},{"first_name":"Hani","full_name":"Gabra, Hani","last_name":"Gabra"},{"full_name":"Taube, Eliane T.","last_name":"Taube","first_name":"Eliane T."},{"full_name":"Dorigo, Oliver","last_name":"Dorigo","first_name":"Oliver"},{"first_name":"David","full_name":"Horst, David","last_name":"Horst"},{"first_name":"Carlotta","last_name":"Keunecke","full_name":"Keunecke, Carlotta"},{"full_name":"Baum, Joanna","last_name":"Baum","first_name":"Joanna"},{"last_name":"Angelotti","full_name":"Angelotti, Timothy","first_name":"Timothy"},{"first_name":"Jalid","last_name":"Sehouli","full_name":"Sehouli, Jalid"},{"last_name":"Braicu","full_name":"Braicu, Elena Ioana","first_name":"Elena Ioana"}]},{"citation":{"short":"S. Mathur, Z.R. Claytor, Â.R.G. Santos, R.A. García, L. Amard, L.A. Bugnet, E. Corsaro, A. Bonanno, S.N. Breton, D. Godoy-Rivera, M.H. Pinsonneault, J. van Saders, The Astrophysical Journal 952 (2023).","apa":"Mathur, S., Claytor, Z. R., Santos, Â. R. G., García, R. A., Amard, L., Bugnet, L. A., … van Saders, J. (2023). Magnetic activity evolution of solar-like stars. I. Sph–age relation derived from Kepler observations. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/acd118\">https://doi.org/10.3847/1538-4357/acd118</a>","ieee":"S. Mathur <i>et al.</i>, “Magnetic activity evolution of solar-like stars. I. Sph–age relation derived from Kepler observations,” <i>The Astrophysical Journal</i>, vol. 952, no. 2. American Astronomical Society, 2023.","ama":"Mathur S, Claytor ZR, Santos ÂRG, et al. Magnetic activity evolution of solar-like stars. I. Sph–age relation derived from Kepler observations. <i>The Astrophysical Journal</i>. 2023;952(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/acd118\">10.3847/1538-4357/acd118</a>","ista":"Mathur S, Claytor ZR, Santos ÂRG, García RA, Amard L, Bugnet LA, Corsaro E, Bonanno A, Breton SN, Godoy-Rivera D, Pinsonneault MH, van Saders J. 2023. Magnetic activity evolution of solar-like stars. I. Sph–age relation derived from Kepler observations. The Astrophysical Journal. 952(2), 131.","chicago":"Mathur, Savita, Zachary R. Claytor, Ângela R. G. Santos, Rafael A. García, Louis Amard, Lisa Annabelle Bugnet, Enrico Corsaro, et al. “Magnetic Activity Evolution of Solar-like Stars. I. Sph–Age Relation Derived from Kepler Observations.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2023. <a href=\"https://doi.org/10.3847/1538-4357/acd118\">https://doi.org/10.3847/1538-4357/acd118</a>.","mla":"Mathur, Savita, et al. “Magnetic Activity Evolution of Solar-like Stars. I. Sph–Age Relation Derived from Kepler Observations.” <i>The Astrophysical Journal</i>, vol. 952, no. 2, 131, American Astronomical Society, 2023, doi:<a href=\"https://doi.org/10.3847/1538-4357/acd118\">10.3847/1538-4357/acd118</a>."},"type":"journal_article","abstract":[{"lang":"eng","text":"The ages of solar-like stars have been at the center of many studies such as exoplanet characterization or Galactic-archeology. While ages are usually computed from stellar evolution models, relations linking ages to other stellar properties, such as rotation and magnetic activity, have been investigated. With the large catalog of 55,232 rotation periods, Prot, and photometric magnetic activity index, Sph from Kepler data, we have the opportunity to look for such magneto-gyro-chronology relations. Stellar ages are obtained with two stellar evolution codes that include treatment of angular momentum evolution, hence using Prot as input in addition to classical atmospheric parameters. We explore two different ways of predicting stellar ages on three subsamples with spectroscopic observations: solar analogs, late-F and G dwarfs, and K dwarfs. We first perform a Bayesian analysis to derive relations between Sph and ages between 1 and 5 Gyr, and other stellar properties. For late-F and G dwarfs, and K dwarfs, the multivariate regression favors the model with Prot and Sph with median differences of 0.1% and 0.2%, respectively. We also apply Machine Learning techniques with a Random Forest algorithm to predict ages up to 14 Gyr with the same set of input parameters. For late-F, G and K dwarfs together, predicted ages are on average within 5.3% of the model ages and improve to 3.1% when including Prot. These are very promising results for a quick age estimation for solar-like stars with photometric observations, especially with current and future space missions."}],"quality_controlled":"1","volume":952,"department":[{"_id":"LiBu"}],"publisher":"American Astronomical Society","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","date_created":"2023-08-01T14:19:16Z","external_id":{"isi":["001034185700001"]},"_id":"13443","month":"08","scopus_import":"1","issue":"2","oa":1,"file":[{"checksum":"f12452834d7ed6748dbf5ace18af4723","content_type":"application/pdf","relation":"main_file","date_updated":"2023-08-02T07:42:26Z","file_id":"13448","access_level":"open_access","creator":"dernst","file_size":4192386,"date_created":"2023-08-02T07:42:26Z","file_name":"2023_AstrophysicalJour_Mathur.pdf","success":1}],"day":"01","doi":"10.3847/1538-4357/acd118","date_published":"2023-08-01T00:00:00Z","intvolume":"       952","article_number":"131","year":"2023","article_type":"original","acknowledgement":"This paper includes data collected by the Kepler mission and obtained from the MAST data archive at the Space Telescope Science Institute (STScI). Funding for the Kepler mission is provided by the NASA Science Mission Directorate. STScI is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5–26555. We acknowledge that this research was supported in part by the National Science Foundation under grant No. NSF PHY-1748958. S.M. acknowledges support from the Spanish Ministry of Science and Innovation (MICINN) with the Ramón y Cajal fellowship No. RYC-2015-17697, the grant No. PID2019-107061GB-C66, and through AEI under the Severo Ochoa Centres of Excellence Programme 2020–2023 (CEX2019-000920-S). S.M. and D.G.R. acknowledge support from the Spanish Ministry of Science and Innovation (MICINN) with the grant No. PID2019-107187GB-I00. Z.R.C. acknowledges support from National Aeronautics and Space Administration via the TESS Guest Investigator Program (grant No. 80NSSC18K18584). The work presented here was partially supported by the NASA grant NNX17AF27G. A.R.G.S. acknowledges the support by FCT through national funds and by FEDER through COMPETE2020 by the following grants: UIDB/04434/2020 and UIDP/04434/2020. A.R.G.S. is supported by FCT through the work contract No. 2020.02480.CEECIND/CP1631/CT0001. R.A.G., L.A., and S.N.B. acknowledge the support from PLATO and GOLF CNES grants. S.N.B. acknowledges support from PLATO ASI-INAF agreement No. 2015-019-R.1-2018.","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"isi":1,"publication":"The Astrophysical Journal","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["520"],"oa_version":"Published Version","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"title":"Magnetic activity evolution of solar-like stars. I. Sph–age relation derived from Kepler observations","author":[{"first_name":"Savita","full_name":"Mathur, Savita","last_name":"Mathur"},{"first_name":"Zachary R.","last_name":"Claytor","full_name":"Claytor, Zachary R."},{"last_name":"Santos","full_name":"Santos, Ângela R. G.","first_name":"Ângela R. G."},{"first_name":"Rafael A.","full_name":"García, Rafael A.","last_name":"García"},{"full_name":"Amard, Louis","last_name":"Amard","first_name":"Louis"},{"first_name":"Lisa Annabelle","orcid":"0000-0003-0142-4000","id":"d9edb345-f866-11ec-9b37-d119b5234501","full_name":"Bugnet, Lisa Annabelle","last_name":"Bugnet"},{"full_name":"Corsaro, Enrico","last_name":"Corsaro","first_name":"Enrico"},{"last_name":"Bonanno","full_name":"Bonanno, Alfio","first_name":"Alfio"},{"last_name":"Breton","full_name":"Breton, Sylvain N.","first_name":"Sylvain N."},{"first_name":"Diego","last_name":"Godoy-Rivera","full_name":"Godoy-Rivera, Diego"},{"first_name":"Marc H.","full_name":"Pinsonneault, Marc H.","last_name":"Pinsonneault"},{"first_name":"Jennifer","last_name":"van Saders","full_name":"van Saders, Jennifer"}],"date_updated":"2024-10-21T06:01:32Z","status":"public","language":[{"iso":"eng"}],"article_processing_charge":"Yes","has_accepted_license":"1","file_date_updated":"2023-08-02T07:42:26Z"},{"article_number":"2307.03237","year":"2023","citation":{"short":"D. Huber, M. Pinsonneault, P. Beck, T.R. Bedding, J.B.-H. Joss Bland-Hawthorn, S.N. Breton, L.A. Bugnet, W.J. Chaplin, R.A. Garcia, S.K. Grunblatt, J.A. Guzik, S. Hekker, S.D. Kawaler, S. Mathis, S. Mathur, T. Metcalfe, B. Mosser, M.K. Ness, A.L. Piro, A. Serenelli, S. Sharma, D.R. Soderblom, K.G. Stassun, D. Stello, J. Tayar, G.T. van Belle, J.C. Zinn, ArXiv (n.d.).","ama":"Huber D, Pinsonneault M, Beck P, et al. Asteroseismology with the Roman galactic bulge time-domain survey. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2307.03237\">10.48550/arXiv.2307.03237</a>","ieee":"D. Huber <i>et al.</i>, “Asteroseismology with the Roman galactic bulge time-domain survey,” <i>arXiv</i>. .","apa":"Huber, D., Pinsonneault, M., Beck, P., Bedding, T. R., Joss Bland-Hawthorn, J. B.-H., Breton, S. N., … Zinn, J. C. (n.d.). Asteroseismology with the Roman galactic bulge time-domain survey. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2307.03237\">https://doi.org/10.48550/arXiv.2307.03237</a>","chicago":"Huber, Daniel, Marc Pinsonneault, Paul Beck, Timothy R. Bedding, Joss Bland-Hawthorn Joss Bland-Hawthorn, Sylvain N. Breton, Lisa Annabelle Bugnet, et al. “Asteroseismology with the Roman Galactic Bulge Time-Domain Survey.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2307.03237\">https://doi.org/10.48550/arXiv.2307.03237</a>.","ista":"Huber D, Pinsonneault M, Beck P, Bedding TR, Joss Bland-Hawthorn JB-H, Breton SN, Bugnet LA, Chaplin WJ, Garcia RA, Grunblatt SK, Guzik JA, Hekker S, Kawaler SD, Mathis S, Mathur S, Metcalfe T, Mosser B, Ness MK, Piro AL, Serenelli A, Sharma S, Soderblom DR, Stassun KG, Stello D, Tayar J, Belle GT van, Zinn JC. Asteroseismology with the Roman galactic bulge time-domain survey. arXiv, 2307.03237.","mla":"Huber, Daniel, et al. “Asteroseismology with the Roman Galactic Bulge Time-Domain Survey.” <i>ArXiv</i>, 2307.03237, doi:<a href=\"https://doi.org/10.48550/arXiv.2307.03237\">10.48550/arXiv.2307.03237</a>."},"oa":1,"type":"preprint","doi":"10.48550/arXiv.2307.03237","day":"06","abstract":[{"lang":"eng","text":"Asteroseismology has transformed stellar astrophysics. Red giant asteroseismology is a prime example, with oscillation periods and amplitudes that are readily detectable with time-domain space-based telescopes. These oscillations can be used to infer masses, ages and radii for large numbers of stars, providing unique constraints on stellar populations in our galaxy. The cadence, duration, and spatial resolution of the Roman galactic bulge time-domain survey (GBTDS) are well-suited for asteroseismology and will probe an important population not studied by prior missions. We identify photometric precision as a key requirement for realizing the potential of asteroseismology with Roman. A precision of 1 mmag per 15-min cadence or better for saturated stars will enable detections of the populous red clump star population in the Galactic bulge. If the survey efficiency is better than expected, we argue for repeat observations of the same fields to improve photometric precision, or covering additional fields to expand the stellar population reach if the photometric precision for saturated stars is better than 1 mmag. Asteroseismology is relatively insensitive to the timing of the observations during the mission, and the prime red clump targets can be observed in a single 70 day campaign in any given field. Complementary stellar characterization, particularly astrometry tied to the Gaia system, will also dramatically expand the diagnostic power of asteroseismology. We also highlight synergies to Roman GBTDS exoplanet science using transits and microlensing."}],"date_published":"2023-07-06T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2307.03237"}],"department":[{"_id":"LiBu"}],"arxiv":1,"publication":"arXiv","external_id":{"arxiv":["2307.03237"]},"publication_status":"submitted","oa_version":"Preprint","date_created":"2023-08-02T07:30:43Z","language":[{"iso":"eng"}],"status":"public","month":"07","article_processing_charge":"No","title":"Asteroseismology with the Roman galactic bulge time-domain survey","author":[{"first_name":"Daniel","last_name":"Huber","full_name":"Huber, Daniel"},{"full_name":"Pinsonneault, Marc","last_name":"Pinsonneault","first_name":"Marc"},{"first_name":"Paul","full_name":"Beck, Paul","last_name":"Beck"},{"full_name":"Bedding, Timothy R.","last_name":"Bedding","first_name":"Timothy R."},{"first_name":"Joss Bland-Hawthorn","last_name":"Joss Bland-Hawthorn","full_name":"Joss Bland-Hawthorn, Joss Bland-Hawthorn"},{"first_name":"Sylvain N.","last_name":"Breton","full_name":"Breton, Sylvain N."},{"first_name":"Lisa Annabelle","orcid":"0000-0003-0142-4000","last_name":"Bugnet","full_name":"Bugnet, Lisa Annabelle","id":"d9edb345-f866-11ec-9b37-d119b5234501"},{"last_name":"Chaplin","full_name":"Chaplin, William J.","first_name":"William J."},{"first_name":"Rafael A.","full_name":"Garcia, Rafael A.","last_name":"Garcia"},{"last_name":"Grunblatt","full_name":"Grunblatt, Samuel K.","first_name":"Samuel K."},{"first_name":"Joyce A.","last_name":"Guzik","full_name":"Guzik, Joyce A."},{"last_name":"Hekker","full_name":"Hekker, Saskia","first_name":"Saskia"},{"first_name":"Steven D.","last_name":"Kawaler","full_name":"Kawaler, Steven D."},{"last_name":"Mathis","full_name":"Mathis, Stephane","first_name":"Stephane"},{"last_name":"Mathur","full_name":"Mathur, Savita","first_name":"Savita"},{"first_name":"Travis","last_name":"Metcalfe","full_name":"Metcalfe, Travis"},{"full_name":"Mosser, Benoit","last_name":"Mosser","first_name":"Benoit"},{"full_name":"Ness, Melissa K.","last_name":"Ness","first_name":"Melissa K."},{"full_name":"Piro, Anthony L.","last_name":"Piro","first_name":"Anthony L."},{"first_name":"Aldo","full_name":"Serenelli, Aldo","last_name":"Serenelli"},{"first_name":"Sanjib","full_name":"Sharma, Sanjib","last_name":"Sharma"},{"first_name":"David R.","last_name":"Soderblom","full_name":"Soderblom, David R."},{"first_name":"Keivan G.","full_name":"Stassun, Keivan G.","last_name":"Stassun"},{"last_name":"Stello","full_name":"Stello, Dennis","first_name":"Dennis"},{"first_name":"Jamie","full_name":"Tayar, Jamie","last_name":"Tayar"},{"full_name":"Belle, Gerard T. van","last_name":"Belle","first_name":"Gerard T. van"},{"full_name":"Zinn, Joel C.","last_name":"Zinn","first_name":"Joel C."}],"_id":"13447","date_updated":"2023-08-02T07:36:00Z"},{"quality_controlled":"1","citation":{"short":"S. Geen, P. Agrawal, P.A. Crowther, B.W. Keller, A. de Koter, Z. Keszthelyi, F. van de Voort, A.A. Ali, F. Backs, L. Bonne, V. Brugaletta, A. Derkink, S. Ekström, Y.A. Fichtner, L. Grassitelli, Y.L.L. Götberg, E.R. Higgins, E. Laplace, K. You Liow, M. Lorenzo, A.F. McLeod, G. Meynet, M. Newsome, G. André Oliva, V. Ramachandran, M.P. Rey, S. Rieder, E. Romano-Díaz, G. Sabhahit, A.A.C. Sander, R. Sarwar, H. Stinshoff, M. Stoop, D. Szécsi, M. Trebitsch, J.S. Vink, E. Winch, Publications of the Astronomical Society of the Pacific 135 (2023).","mla":"Geen, Sam, et al. “Bringing Stellar Evolution and Feedback Together: Summary of Proposals from the Lorentz Center Workshop.” <i>Publications of the Astronomical Society of the Pacific</i>, vol. 135, no. 1044, 021001, IOP Publishing, 2023, doi:<a href=\"https://doi.org/10.1088/1538-3873/acb6b5\">10.1088/1538-3873/acb6b5</a>.","chicago":"Geen, Sam, Poojan Agrawal, Paul A. Crowther, B. W. Keller, Alex de Koter, Zsolt Keszthelyi, Freeke van de Voort, et al. “Bringing Stellar Evolution and Feedback Together: Summary of Proposals from the Lorentz Center Workshop.” <i>Publications of the Astronomical Society of the Pacific</i>. IOP Publishing, 2023. <a href=\"https://doi.org/10.1088/1538-3873/acb6b5\">https://doi.org/10.1088/1538-3873/acb6b5</a>.","ista":"Geen S, Agrawal P, Crowther PA, Keller BW, de Koter A, Keszthelyi Z, van de Voort F, Ali AA, Backs F, Bonne L, Brugaletta V, Derkink A, Ekström S, Fichtner YA, Grassitelli L, Götberg YLL, Higgins ER, Laplace E, You Liow K, Lorenzo M, McLeod AF, Meynet G, Newsome M, André Oliva G, Ramachandran V, Rey MP, Rieder S, Romano-Díaz E, Sabhahit G, Sander AAC, Sarwar R, Stinshoff H, Stoop M, Szécsi D, Trebitsch M, Vink JS, Winch E. 2023. Bringing stellar evolution and feedback together: Summary of proposals from the Lorentz Center workshop. Publications of the Astronomical Society of the Pacific. 135(1044), 021001.","ama":"Geen S, Agrawal P, Crowther PA, et al. Bringing stellar evolution and feedback together: Summary of proposals from the Lorentz Center workshop. <i>Publications of the Astronomical Society of the Pacific</i>. 2023;135(1044). doi:<a href=\"https://doi.org/10.1088/1538-3873/acb6b5\">10.1088/1538-3873/acb6b5</a>","apa":"Geen, S., Agrawal, P., Crowther, P. A., Keller, B. W., de Koter, A., Keszthelyi, Z., … Winch, E. (2023). Bringing stellar evolution and feedback together: Summary of proposals from the Lorentz Center workshop. <i>Publications of the Astronomical Society of the Pacific</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1538-3873/acb6b5\">https://doi.org/10.1088/1538-3873/acb6b5</a>","ieee":"S. Geen <i>et al.</i>, “Bringing stellar evolution and feedback together: Summary of proposals from the Lorentz Center workshop,” <i>Publications of the Astronomical Society of the Pacific</i>, vol. 135, no. 1044. IOP Publishing, 2023."},"extern":"1","abstract":[{"text":"Stars strongly impact their environment, and shape structures on all scales throughout the universe, in a process known as \"feedback.\" Due to the complexity of both stellar evolution and the physics of larger astrophysical structures, there remain many unanswered questions about how feedback operates and what we can learn about stars by studying their imprint on the wider universe. In this white paper, we summarize discussions from the Lorentz Center meeting \"Bringing Stellar Evolution and Feedback Together\" in 2022 April and identify key areas where further dialog can bring about radical changes in how we view the relationship between stars and the universe they live in.","lang":"eng"}],"type":"journal_article","volume":135,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1088/1538-3873/acb6b5"}],"publisher":"IOP Publishing","date_created":"2023-08-03T10:09:57Z","publication_status":"published","external_id":{"arxiv":["2301.13611"]},"_id":"13449","scopus_import":"1","issue":"1044","month":"03","date_published":"2023-03-09T00:00:00Z","intvolume":"       135","oa":1,"day":"09","doi":"10.1088/1538-3873/acb6b5","publication_identifier":{"issn":["0004-6280"],"eissn":["1538-3873"]},"year":"2023","article_type":"original","article_number":"021001","arxiv":1,"publication":"Publications of the Astronomical Society of the Pacific","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"date_updated":"2023-08-21T12:09:14Z","title":"Bringing stellar evolution and feedback together: Summary of proposals from the Lorentz Center workshop","author":[{"full_name":"Geen, Sam","last_name":"Geen","first_name":"Sam"},{"first_name":"Poojan","last_name":"Agrawal","full_name":"Agrawal, Poojan"},{"first_name":"Paul A.","last_name":"Crowther","full_name":"Crowther, Paul A."},{"full_name":"Keller, B. W.","last_name":"Keller","first_name":"B. W."},{"full_name":"de Koter, Alex","last_name":"de Koter","first_name":"Alex"},{"last_name":"Keszthelyi","full_name":"Keszthelyi, Zsolt","first_name":"Zsolt"},{"full_name":"van de Voort, Freeke","last_name":"van de Voort","first_name":"Freeke"},{"first_name":"Ahmad A.","last_name":"Ali","full_name":"Ali, Ahmad A."},{"first_name":"Frank","full_name":"Backs, Frank","last_name":"Backs"},{"full_name":"Bonne, Lars","last_name":"Bonne","first_name":"Lars"},{"last_name":"Brugaletta","full_name":"Brugaletta, Vittoria","first_name":"Vittoria"},{"first_name":"Annelotte","last_name":"Derkink","full_name":"Derkink, Annelotte"},{"last_name":"Ekström","full_name":"Ekström, Sylvia","first_name":"Sylvia"},{"full_name":"Fichtner, Yvonne A.","last_name":"Fichtner","first_name":"Yvonne A."},{"full_name":"Grassitelli, Luca","last_name":"Grassitelli","first_name":"Luca"},{"last_name":"Götberg","full_name":"Götberg, Ylva Louise Linsdotter","id":"d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d","orcid":"0000-0002-6960-6911","first_name":"Ylva Louise Linsdotter"},{"full_name":"Higgins, Erin R.","last_name":"Higgins","first_name":"Erin R."},{"full_name":"Laplace, Eva","last_name":"Laplace","first_name":"Eva"},{"first_name":"Kong","last_name":"You Liow","full_name":"You Liow, Kong"},{"full_name":"Lorenzo, Marta","last_name":"Lorenzo","first_name":"Marta"},{"first_name":"Anna F.","full_name":"McLeod, Anna F.","last_name":"McLeod"},{"first_name":"Georges","last_name":"Meynet","full_name":"Meynet, Georges"},{"first_name":"Megan","last_name":"Newsome","full_name":"Newsome, Megan"},{"first_name":"G.","last_name":"André Oliva","full_name":"André Oliva, G."},{"first_name":"Varsha","last_name":"Ramachandran","full_name":"Ramachandran, Varsha"},{"first_name":"Martin P.","full_name":"Rey, Martin P.","last_name":"Rey"},{"first_name":"Steven","full_name":"Rieder, Steven","last_name":"Rieder"},{"full_name":"Romano-Díaz, Emilio","last_name":"Romano-Díaz","first_name":"Emilio"},{"first_name":"Gautham","full_name":"Sabhahit, Gautham","last_name":"Sabhahit"},{"last_name":"Sander","full_name":"Sander, Andreas A. C.","first_name":"Andreas A. C."},{"full_name":"Sarwar, Rafia","last_name":"Sarwar","first_name":"Rafia"},{"first_name":"Hanno","last_name":"Stinshoff","full_name":"Stinshoff, Hanno"},{"first_name":"Mitchel","last_name":"Stoop","full_name":"Stoop, Mitchel"},{"first_name":"Dorottya","full_name":"Szécsi, Dorottya","last_name":"Szécsi"},{"first_name":"Maxime","last_name":"Trebitsch","full_name":"Trebitsch, Maxime"},{"last_name":"Vink","full_name":"Vink, Jorick S.","first_name":"Jorick S."},{"first_name":"Ethan","full_name":"Winch, Ethan","last_name":"Winch"}],"article_processing_charge":"No","status":"public","language":[{"iso":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"publication":"The Astrophysical Journal","year":"2023","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"article_type":"original","article_number":"18","date_published":"2023-01-20T00:00:00Z","intvolume":"       943","oa":1,"day":"20","doi":"10.3847/1538-4357/aca655","article_processing_charge":"No","status":"public","language":[{"iso":"eng"}],"date_updated":"2023-08-21T12:07:05Z","title":"Cool, luminous, and highly variable stars in the Magellanic Clouds. II. Spectroscopic and environmental analysis of Thorne–Żytkow object and super-AGB star candidates","author":[{"last_name":"O‘Grady","full_name":"O‘Grady, Anna J. G.","first_name":"Anna J. G."},{"full_name":"Drout, Maria R.","last_name":"Drout","first_name":"Maria R."},{"last_name":"Gaensler","full_name":"Gaensler, B. M.","first_name":"B. M."},{"full_name":"Kochanek, C. S.","last_name":"Kochanek","first_name":"C. S."},{"first_name":"Kathryn F.","last_name":"Neugent","full_name":"Neugent, Kathryn F."},{"full_name":"Doherty, Carolyn L.","last_name":"Doherty","first_name":"Carolyn L."},{"last_name":"Speagle","full_name":"Speagle, Joshua S.","first_name":"Joshua S."},{"last_name":"Shappee","full_name":"Shappee, B. J.","first_name":"B. J."},{"first_name":"Michael","full_name":"Rauch, Michael","last_name":"Rauch"},{"first_name":"Ylva Louise Linsdotter","last_name":"Götberg","full_name":"Götberg, Ylva Louise Linsdotter","id":"d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d","orcid":"0000-0002-6960-6911"},{"full_name":"Ludwig, Bethany","last_name":"Ludwig","first_name":"Bethany"},{"full_name":"Thompson, Todd A.","last_name":"Thompson","first_name":"Todd A."}],"keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.3847/1538-4357/aca655","open_access":"1"}],"publisher":"American Astronomical Society","volume":943,"quality_controlled":"1","citation":{"ieee":"A. J. G. O‘Grady <i>et al.</i>, “Cool, luminous, and highly variable stars in the Magellanic Clouds. II. Spectroscopic and environmental analysis of Thorne–Żytkow object and super-AGB star candidates,” <i>The Astrophysical Journal</i>, vol. 943, no. 1. American Astronomical Society, 2023.","apa":"O‘Grady, A. J. G., Drout, M. R., Gaensler, B. M., Kochanek, C. S., Neugent, K. F., Doherty, C. L., … Thompson, T. A. (2023). Cool, luminous, and highly variable stars in the Magellanic Clouds. II. Spectroscopic and environmental analysis of Thorne–Żytkow object and super-AGB star candidates. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/aca655\">https://doi.org/10.3847/1538-4357/aca655</a>","ama":"O‘Grady AJG, Drout MR, Gaensler BM, et al. Cool, luminous, and highly variable stars in the Magellanic Clouds. II. Spectroscopic and environmental analysis of Thorne–Żytkow object and super-AGB star candidates. <i>The Astrophysical Journal</i>. 2023;943(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/aca655\">10.3847/1538-4357/aca655</a>","mla":"O‘Grady, Anna J. G., et al. “Cool, Luminous, and Highly Variable Stars in the Magellanic Clouds. II. Spectroscopic and Environmental Analysis of Thorne–Żytkow Object and Super-AGB Star Candidates.” <i>The Astrophysical Journal</i>, vol. 943, no. 1, 18, American Astronomical Society, 2023, doi:<a href=\"https://doi.org/10.3847/1538-4357/aca655\">10.3847/1538-4357/aca655</a>.","ista":"O‘Grady AJG, Drout MR, Gaensler BM, Kochanek CS, Neugent KF, Doherty CL, Speagle JS, Shappee BJ, Rauch M, Götberg YLL, Ludwig B, Thompson TA. 2023. Cool, luminous, and highly variable stars in the Magellanic Clouds. II. Spectroscopic and environmental analysis of Thorne–Żytkow object and super-AGB star candidates. The Astrophysical Journal. 943(1), 18.","chicago":"O‘Grady, Anna J. G., Maria R. Drout, B. M. Gaensler, C. S. Kochanek, Kathryn F. Neugent, Carolyn L. Doherty, Joshua S. Speagle, et al. “Cool, Luminous, and Highly Variable Stars in the Magellanic Clouds. II. Spectroscopic and Environmental Analysis of Thorne–Żytkow Object and Super-AGB Star Candidates.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2023. <a href=\"https://doi.org/10.3847/1538-4357/aca655\">https://doi.org/10.3847/1538-4357/aca655</a>.","short":"A.J.G. O‘Grady, M.R. Drout, B.M. Gaensler, C.S. Kochanek, K.F. Neugent, C.L. Doherty, J.S. Speagle, B.J. Shappee, M. Rauch, Y.L.L. Götberg, B. Ludwig, T.A. Thompson, The Astrophysical Journal 943 (2023)."},"type":"journal_article","abstract":[{"text":"In previous work, we identified a population of 38 cool and luminous variable stars in the Magellanic Clouds and examined 11 in detail in order to classify them as either Thorne–Żytkow objects (TŻOs; red supergiants with a neutron star cores) or super-asymptotic giant branch (sAGB) stars (the most massive stars that will not undergo core collapse). This population includes HV 2112, a peculiar star previously considered in other works to be either a TŻO or high-mass asymptotic giant branch (AGB) star. Here we continue this investigation, using the kinematic and radio environments and local star formation history of these stars to place constraints on the age of the progenitor systems and the presence of past supernovae. These stars are not associated with regions of recent star formation, and we find no evidence of past supernovae at their locations. Finally, we also assess the presence of heavy elements and lithium in their spectra compared to red supergiants. We find strong absorption in Li and s-process elements compared to RSGs in most of the sample, consistent with sAGB nucleosynthesis, while HV 2112 shows additional strong lines associated with TŻO nucleosynthesis. Coupled with our previous mass estimates, the results are consistent with the stars being massive (∼4–6.5 M⊙) or sAGB (∼6.5–12 M⊙) stars in the thermally pulsing phase, providing crucial observations of the transition between low- and high-mass stellar populations. HV 2112 is more ambiguous; it could either be a maximally massive sAGB star, or a TŻO if the minimum mass for stability extends down to ≲13 M⊙.","lang":"eng"}],"extern":"1","issue":"1","scopus_import":"1","month":"01","_id":"13450","external_id":{"arxiv":["2211.12438"]},"date_created":"2023-08-03T10:10:12Z","publication_status":"published"},{"external_id":{"arxiv":["2303.16876"]},"publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_created":"2023-08-05T18:25:22Z","month":"08","scopus_import":"1","issue":"5","_id":"13963","abstract":[{"lang":"eng","text":"The many-body localization (MBL) proximity effect is an intriguing phenomenon where a thermal bath localizes due to the interaction with a disordered system. The interplay of thermal and nonergodic behavior in these systems gives rise to a rich phase diagram, whose exploration is an active field of research. In this paper, we study a bosonic Hubbard model featuring two particle species representing the bath and the disordered system. Using state-of-the-art numerical techniques, we investigate the dynamics of the model in different regimes, based on which we obtain a tentative phase diagram as a function of coupling strength and bath size. When the bath is composed of a single particle, we observe clear signatures of a transition from an MBL proximity effect to a delocalized phase. Increasing the bath size, however, its thermalizing effect becomes stronger and eventually the whole system delocalizes in the range of moderate interaction strengths studied. In this regime, we characterize particle transport, revealing diffusive behavior of the originally localized bosons."}],"type":"journal_article","citation":{"short":"P. Brighi, M. Ljubotina, D.A. Abanin, M. Serbyn, Physical Review B 108 (2023).","apa":"Brighi, P., Ljubotina, M., Abanin, D. A., &#38; Serbyn, M. (2023). Many-body localization proximity effect in a two-species bosonic Hubbard model. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevb.108.054201\">https://doi.org/10.1103/physrevb.108.054201</a>","ama":"Brighi P, Ljubotina M, Abanin DA, Serbyn M. Many-body localization proximity effect in a two-species bosonic Hubbard model. <i>Physical Review B</i>. 2023;108(5). doi:<a href=\"https://doi.org/10.1103/physrevb.108.054201\">10.1103/physrevb.108.054201</a>","ieee":"P. Brighi, M. Ljubotina, D. A. Abanin, and M. Serbyn, “Many-body localization proximity effect in a two-species bosonic Hubbard model,” <i>Physical Review B</i>, vol. 108, no. 5. American Physical Society, 2023.","chicago":"Brighi, Pietro, Marko Ljubotina, Dmitry A. Abanin, and Maksym Serbyn. “Many-Body Localization Proximity Effect in a Two-Species Bosonic Hubbard Model.” <i>Physical Review B</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/physrevb.108.054201\">https://doi.org/10.1103/physrevb.108.054201</a>.","ista":"Brighi P, Ljubotina M, Abanin DA, Serbyn M. 2023. Many-body localization proximity effect in a two-species bosonic Hubbard model. Physical Review B. 108(5), 054201.","mla":"Brighi, Pietro, et al. “Many-Body Localization Proximity Effect in a Two-Species Bosonic Hubbard Model.” <i>Physical Review B</i>, vol. 108, no. 5, 054201, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/physrevb.108.054201\">10.1103/physrevb.108.054201</a>."},"quality_controlled":"1","publisher":"American Physical Society","corr_author":"1","volume":108,"department":[{"_id":"MaSe"}],"oa_version":"Published Version","language":[{"iso":"eng"}],"status":"public","file_date_updated":"2023-08-07T09:48:08Z","has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","title":"Many-body localization proximity effect in a two-species bosonic Hubbard model","author":[{"first_name":"Pietro","full_name":"Brighi, Pietro","last_name":"Brighi","id":"4115AF5C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7969-2729"},{"orcid":"0000-0003-0038-7068","id":"F75EE9BE-5C90-11EA-905D-16643DDC885E","last_name":"Ljubotina","full_name":"Ljubotina, Marko","first_name":"Marko"},{"full_name":"Abanin, Dmitry A.","last_name":"Abanin","first_name":"Dmitry A."},{"first_name":"Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","last_name":"Serbyn","orcid":"0000-0002-2399-5827"}],"date_updated":"2025-04-14T07:52:06Z","article_number":"054201","ec_funded":1,"publication_identifier":{"issn":["2469-9950"],"eissn":["2469-9969"]},"year":"2023","article_type":"original","acknowledgement":"We thank A. A. Michailidis and A. Mirlin for insightful discussions. P.B., M.L., and M.S. acknowledge support by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899). D.A. was\r\nsupported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 864597) and by the Swiss National Science Foundation. P.B., M.L., and M.S. acknowledge PRACE for awarding us access to Joliot-Curie at GENCI@CEA, France, where the TEBD simulations were performed. The TEBD simulations were performed using the ITensor library [60].","doi":"10.1103/physrevb.108.054201","day":"01","oa":1,"file":[{"file_id":"13981","date_updated":"2023-08-07T09:48:08Z","relation":"main_file","checksum":"f763000339b5fd543c14377109920690","content_type":"application/pdf","date_created":"2023-08-07T09:48:08Z","success":1,"file_name":"2023_PhysRevB_Brighi.pdf","file_size":3051398,"creator":"dernst","access_level":"open_access"}],"intvolume":"       108","date_published":"2023-08-01T00:00:00Z","project":[{"name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","grant_number":"850899","call_identifier":"H2020"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["530"],"arxiv":1,"publication":"Physical Review B"},{"external_id":{"pmid":["37441873"],"isi":["001047020200001"]},"date_created":"2023-08-06T22:01:10Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"issue":"8","scopus_import":"1","month":"08","_id":"13965","quality_controlled":"1","type":"journal_article","pmid":1,"abstract":[{"text":"Many modes and mechanisms of epigenetic inheritance have been elucidated in eukaryotes. Most of them are relatively short-term, generally not exceeding one or a few organismal generations. However, emerging evidence indicates that one mechanism, cytosine DNA methylation, can mediate epigenetic inheritance over much longer timescales, which are mostly or completely inaccessible in the laboratory. Here we discuss the evidence for, and mechanisms and implications of, such long-term epigenetic inheritance. We argue that compelling evidence supports the long-term epigenetic inheritance of gene body methylation, at least in the model angiosperm Arabidopsis thaliana, and that variation in such methylation can therefore serve as an epigenetic basis for phenotypic variation in natural populations.","lang":"eng"}],"citation":{"short":"E. Hollwey, A. Briffa, M. Howard, D. Zilberman, Current Opinion in Genetics and Development 81 (2023).","mla":"Hollwey, Elizabeth, et al. “Concepts, Mechanisms and Implications of Long-Term Epigenetic Inheritance.” <i>Current Opinion in Genetics and Development</i>, vol. 81, no. 8, 102087, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.gde.2023.102087\">10.1016/j.gde.2023.102087</a>.","ista":"Hollwey E, Briffa A, Howard M, Zilberman D. 2023. Concepts, mechanisms and implications of long-term epigenetic inheritance. Current Opinion in Genetics and Development. 81(8), 102087.","chicago":"Hollwey, Elizabeth, Amy Briffa, Martin Howard, and Daniel Zilberman. “Concepts, Mechanisms and Implications of Long-Term Epigenetic Inheritance.” <i>Current Opinion in Genetics and Development</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.gde.2023.102087\">https://doi.org/10.1016/j.gde.2023.102087</a>.","ieee":"E. Hollwey, A. Briffa, M. Howard, and D. Zilberman, “Concepts, mechanisms and implications of long-term epigenetic inheritance,” <i>Current Opinion in Genetics and Development</i>, vol. 81, no. 8. Elsevier, 2023.","ama":"Hollwey E, Briffa A, Howard M, Zilberman D. Concepts, mechanisms and implications of long-term epigenetic inheritance. <i>Current Opinion in Genetics and Development</i>. 2023;81(8). doi:<a href=\"https://doi.org/10.1016/j.gde.2023.102087\">10.1016/j.gde.2023.102087</a>","apa":"Hollwey, E., Briffa, A., Howard, M., &#38; Zilberman, D. (2023). Concepts, mechanisms and implications of long-term epigenetic inheritance. <i>Current Opinion in Genetics and Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2023.102087\">https://doi.org/10.1016/j.gde.2023.102087</a>"},"publisher":"Elsevier","corr_author":"1","department":[{"_id":"DaZi"}],"volume":81,"oa_version":"Published Version","file_date_updated":"2023-08-07T08:32:26Z","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","language":[{"iso":"eng"}],"status":"public","date_updated":"2024-10-09T21:06:16Z","author":[{"id":"b8c4f54b-e484-11eb-8fdc-a54df64ef6dd","full_name":"Hollwey, Elizabeth","last_name":"Hollwey","first_name":"Elizabeth"},{"first_name":"Amy","full_name":"Briffa, Amy","last_name":"Briffa"},{"last_name":"Howard","full_name":"Howard, Martin","first_name":"Martin"},{"first_name":"Daniel","orcid":"0000-0002-0123-8649","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1","full_name":"Zilberman, Daniel","last_name":"Zilberman"}],"title":"Concepts, mechanisms and implications of long-term epigenetic inheritance","year":"2023","article_type":"original","publication_identifier":{"issn":["0959-437X"],"eissn":["1879-0380"]},"article_number":"102087","intvolume":"        81","date_published":"2023-08-01T00:00:00Z","day":"01","doi":"10.1016/j.gde.2023.102087","oa":1,"file":[{"access_level":"open_access","creator":"dernst","file_size":2568632,"file_name":"2023_CurrentOpinionGenetics_Hollwey.pdf","success":1,"date_created":"2023-08-07T08:32:26Z","content_type":"application/pdf","checksum":"a294cd9506b80ed6ef218ef44ed32765","relation":"main_file","date_updated":"2023-08-07T08:32:26Z","file_id":"13980"}],"ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Current Opinion in Genetics and Development","isi":1},{"volume":108,"department":[{"_id":"MiLe"},{"_id":"TaHa"}],"corr_author":"1","publisher":"American Physical Society","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2203.12666","open_access":"1"}],"citation":{"short":"G. Bighin, Q.P. Ho, M. Lemeshko, T.V. Tscherbul, Physical Review B 108 (2023).","ieee":"G. Bighin, Q. P. Ho, M. Lemeshko, and T. V. Tscherbul, “Diagrammatic Monte Carlo for electronic correlation in molecules: High-order many-body perturbation theory with low scaling,” <i>Physical Review B</i>, vol. 108, no. 4. American Physical Society, 2023.","apa":"Bighin, G., Ho, Q. P., Lemeshko, M., &#38; Tscherbul, T. V. (2023). Diagrammatic Monte Carlo for electronic correlation in molecules: High-order many-body perturbation theory with low scaling. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.108.045115\">https://doi.org/10.1103/PhysRevB.108.045115</a>","ama":"Bighin G, Ho QP, Lemeshko M, Tscherbul TV. Diagrammatic Monte Carlo for electronic correlation in molecules: High-order many-body perturbation theory with low scaling. <i>Physical Review B</i>. 2023;108(4). doi:<a href=\"https://doi.org/10.1103/PhysRevB.108.045115\">10.1103/PhysRevB.108.045115</a>","ista":"Bighin G, Ho QP, Lemeshko M, Tscherbul TV. 2023. Diagrammatic Monte Carlo for electronic correlation in molecules: High-order many-body perturbation theory with low scaling. Physical Review B. 108(4), 045115.","chicago":"Bighin, Giacomo, Quoc P Ho, Mikhail Lemeshko, and T. V. Tscherbul. “Diagrammatic Monte Carlo for Electronic Correlation in Molecules: High-Order Many-Body Perturbation Theory with Low Scaling.” <i>Physical Review B</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/PhysRevB.108.045115\">https://doi.org/10.1103/PhysRevB.108.045115</a>.","mla":"Bighin, Giacomo, et al. “Diagrammatic Monte Carlo for Electronic Correlation in Molecules: High-Order Many-Body Perturbation Theory with Low Scaling.” <i>Physical Review B</i>, vol. 108, no. 4, 045115, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/PhysRevB.108.045115\">10.1103/PhysRevB.108.045115</a>."},"abstract":[{"text":"We present a low-scaling diagrammatic Monte Carlo approach to molecular correlation energies. Using combinatorial graph theory to encode many-body Hugenholtz diagrams, we sample the Møller-Plesset (MPn) perturbation series, obtaining accurate correlation energies up to n=5, with quadratic scaling in the number of basis functions. Our technique reduces the computational complexity of the molecular many-fermion correlation problem, opening up the possibility of low-scaling, accurate stochastic computations for a wide class of many-body systems described by Hugenholtz diagrams.","lang":"eng"}],"type":"journal_article","quality_controlled":"1","_id":"13966","month":"07","issue":"4","scopus_import":"1","publication_status":"published","date_created":"2023-08-06T22:01:10Z","external_id":{"arxiv":["2203.12666"],"isi":["001532067800001"]},"isi":1,"publication":"Physical Review B","arxiv":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","project":[{"grant_number":"M02641","name":"A path-integral approach to composite impurities","_id":"26986C82-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"grant_number":"M02751","_id":"26B96266-B435-11E9-9278-68D0E5697425","name":"Algebro-Geometric Applications of Factorization Homology","call_identifier":"FWF"},{"call_identifier":"FWF","grant_number":"P29902","name":"Quantum rotations in the presence of a many-body environment","_id":"26031614-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","name":"Angulon: physics and applications of a new quasiparticle","_id":"2688CF98-B435-11E9-9278-68D0E5697425","grant_number":"801770"}],"oa":1,"day":"15","doi":"10.1103/PhysRevB.108.045115","date_published":"2023-07-15T00:00:00Z","intvolume":"       108","article_number":"045115","publication_identifier":{"issn":["2469-9950"],"eissn":["2469-9969"]},"year":"2023","acknowledgement":"We acknowledge stimulating discussions with Sergey Varganov, Artur Izmaylov, Jacek Kłos, Piotr Żuchowski, Dominika Zgid, Nikolay Prokof'ev, Boris Svistunov, Robert Parrish, and Andreas Heßelmann. G.B. and Q.P.H. acknowledge support from the Austrian Science Fund (FWF) under Projects No. M2641-N27 and No. M2751. M.L. acknowledges support by the FWF under Project No. P29902-N27, and by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). T.V.T. was supported by the NSF CAREER award No. PHY-2045681. This work is supported by the German Research Foundation (DFG) under Germany's Excellence Strategy EXC2181/1-390900948 (the Heidelberg STRUCTURES Excellence Cluster). The authors acknowledge support by the state of Baden-Württemberg through bwHPC.","article_type":"original","ec_funded":1,"author":[{"orcid":"0000-0001-8823-9777","id":"4CA96FD4-F248-11E8-B48F-1D18A9856A87","full_name":"Bighin, Giacomo","last_name":"Bighin","first_name":"Giacomo"},{"orcid":"0000-0001-6889-1418","id":"3DD82E3C-F248-11E8-B48F-1D18A9856A87","last_name":"Ho","full_name":"Ho, Quoc P","first_name":"Quoc P"},{"first_name":"Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","full_name":"Lemeshko, Mikhail"},{"first_name":"T. V.","full_name":"Tscherbul, T. V.","last_name":"Tscherbul"}],"title":"Diagrammatic Monte Carlo for electronic correlation in molecules: High-order many-body perturbation theory with low scaling","date_updated":"2025-09-09T12:45:32Z","language":[{"iso":"eng"}],"status":"public","article_processing_charge":"No","oa_version":"Preprint"},{"date_updated":"2025-07-10T11:50:43Z","title":"Stopping criteria for value iteration on stochastic games with quantitative objectives","author":[{"orcid":"0000-0002-8122-2881","full_name":"Kretinsky, Jan","last_name":"Kretinsky","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","first_name":"Jan"},{"orcid":"0000-0002-1712-2165","full_name":"Meggendorfer, Tobias","last_name":"Meggendorfer","id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1","first_name":"Tobias"},{"id":"02ab0197-cc70-11ed-ab61-918e71f56881","full_name":"Weininger, Maximilian","last_name":"Weininger","first_name":"Maximilian"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"status":"public","oa_version":"Preprint","publication":"38th Annual ACM/IEEE Symposium on Logic in Computer Science","arxiv":1,"isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"      2023","date_published":"2023-07-01T00:00:00Z","day":"01","doi":"10.1109/LICS56636.2023.10175771","oa":1,"year":"2023","publication_identifier":{"issn":["1043-6871"],"isbn":["9798350335873"]},"acknowledgement":"This research was funded in part by DFG projects 383882557 “SUV” and 427755713 “GOPro”.","_id":"13967","scopus_import":"1","month":"07","date_created":"2023-08-06T22:01:10Z","publication_status":"published","external_id":{"isi":["001036707700042"],"arxiv":["2304.09930"]},"conference":{"end_date":"2023-06-29","location":"Boston, MA, United States","name":"LICS: Logic in Computer Science","start_date":"2023-06-26"},"department":[{"_id":"KrCh"}],"volume":2023,"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2304.09930","open_access":"1"}],"corr_author":"1","publisher":"Institute of Electrical and Electronics Engineers","quality_controlled":"1","type":"conference","abstract":[{"text":"A classic solution technique for Markov decision processes (MDP) and stochastic games (SG) is value iteration (VI). Due to its good practical performance, this approximative approach is typically preferred over exact techniques, even though no practical bounds on the imprecision of the result could be given until recently. As a consequence, even the most used model checkers could return arbitrarily wrong results. Over the past decade, different works derived stopping criteria, indicating when the precision reaches the desired level, for various settings, in particular MDP with reachability, total reward, and mean payoff, and SG with reachability.In this paper, we provide the first stopping criteria for VI on SG with total reward and mean payoff, yielding the first anytime algorithms in these settings. To this end, we provide the solution in two flavours: First through a reduction to the MDP case and second directly on SG. The former is simpler and automatically utilizes any advances on MDP. The latter allows for more local computations, heading towards better practical efficiency.Our solution unifies the previously mentioned approaches for MDP and SG and their underlying ideas. To achieve this, we isolate objective-specific subroutines as well as identify objective-independent concepts. These structural concepts, while surprisingly simple, form the very essence of the unified solution.","lang":"eng"}],"citation":{"ista":"Kretinsky J, Meggendorfer T, Weininger M. 2023. Stopping criteria for value iteration on stochastic games with quantitative objectives. 38th Annual ACM/IEEE Symposium on Logic in Computer Science. LICS: Logic in Computer Science vol. 2023.","chicago":"Kretinsky, Jan, Tobias Meggendorfer, and Maximilian Weininger. “Stopping Criteria for Value Iteration on Stochastic Games with Quantitative Objectives.” In <i>38th Annual ACM/IEEE Symposium on Logic in Computer Science</i>, Vol. 2023. Institute of Electrical and Electronics Engineers, 2023. <a href=\"https://doi.org/10.1109/LICS56636.2023.10175771\">https://doi.org/10.1109/LICS56636.2023.10175771</a>.","mla":"Kretinsky, Jan, et al. “Stopping Criteria for Value Iteration on Stochastic Games with Quantitative Objectives.” <i>38th Annual ACM/IEEE Symposium on Logic in Computer Science</i>, vol. 2023, Institute of Electrical and Electronics Engineers, 2023, doi:<a href=\"https://doi.org/10.1109/LICS56636.2023.10175771\">10.1109/LICS56636.2023.10175771</a>.","apa":"Kretinsky, J., Meggendorfer, T., &#38; Weininger, M. (2023). Stopping criteria for value iteration on stochastic games with quantitative objectives. In <i>38th Annual ACM/IEEE Symposium on Logic in Computer Science</i> (Vol. 2023). Boston, MA, United States: Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/LICS56636.2023.10175771\">https://doi.org/10.1109/LICS56636.2023.10175771</a>","ama":"Kretinsky J, Meggendorfer T, Weininger M. Stopping criteria for value iteration on stochastic games with quantitative objectives. In: <i>38th Annual ACM/IEEE Symposium on Logic in Computer Science</i>. Vol 2023. Institute of Electrical and Electronics Engineers; 2023. doi:<a href=\"https://doi.org/10.1109/LICS56636.2023.10175771\">10.1109/LICS56636.2023.10175771</a>","ieee":"J. Kretinsky, T. Meggendorfer, and M. Weininger, “Stopping criteria for value iteration on stochastic games with quantitative objectives,” in <i>38th Annual ACM/IEEE Symposium on Logic in Computer Science</i>, Boston, MA, United States, 2023, vol. 2023.","short":"J. Kretinsky, T. Meggendorfer, M. Weininger, in:, 38th Annual ACM/IEEE Symposium on Logic in Computer Science, Institute of Electrical and Electronics Engineers, 2023."}},{"quality_controlled":"1","citation":{"ista":"Hasler R, Steger-Polt MH, Reiner-Rozman C, Fossati S, Lee S, Aspermair P, Kleber C, Ibáñez M, Dostalek J, Knoll W. 2023. Optical and electronic signal stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing. Frontiers in Physics. 11, 1202132.","chicago":"Hasler, Roger, Marie Helene Steger-Polt, Ciril Reiner-Rozman, Stefan Fossati, Seungho Lee, Patrik Aspermair, Christoph Kleber, Maria Ibáñez, Jakub Dostalek, and Wolfgang Knoll. “Optical and Electronic Signal Stabilization of Plasmonic Fiber Optic Gate Electrodes: Towards Improved Real-Time Dual-Mode Biosensing.” <i>Frontiers in Physics</i>. Frontiers, 2023. <a href=\"https://doi.org/10.3389/fphy.2023.1202132\">https://doi.org/10.3389/fphy.2023.1202132</a>.","mla":"Hasler, Roger, et al. “Optical and Electronic Signal Stabilization of Plasmonic Fiber Optic Gate Electrodes: Towards Improved Real-Time Dual-Mode Biosensing.” <i>Frontiers in Physics</i>, vol. 11, 1202132, Frontiers, 2023, doi:<a href=\"https://doi.org/10.3389/fphy.2023.1202132\">10.3389/fphy.2023.1202132</a>.","apa":"Hasler, R., Steger-Polt, M. H., Reiner-Rozman, C., Fossati, S., Lee, S., Aspermair, P., … Knoll, W. (2023). Optical and electronic signal stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing. <i>Frontiers in Physics</i>. Frontiers. <a href=\"https://doi.org/10.3389/fphy.2023.1202132\">https://doi.org/10.3389/fphy.2023.1202132</a>","ieee":"R. Hasler <i>et al.</i>, “Optical and electronic signal stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing,” <i>Frontiers in Physics</i>, vol. 11. Frontiers, 2023.","ama":"Hasler R, Steger-Polt MH, Reiner-Rozman C, et al. Optical and electronic signal stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing. <i>Frontiers in Physics</i>. 2023;11. doi:<a href=\"https://doi.org/10.3389/fphy.2023.1202132\">10.3389/fphy.2023.1202132</a>","short":"R. Hasler, M.H. Steger-Polt, C. Reiner-Rozman, S. Fossati, S. Lee, P. Aspermair, C. Kleber, M. Ibáñez, J. Dostalek, W. Knoll, Frontiers in Physics 11 (2023)."},"type":"journal_article","abstract":[{"lang":"eng","text":"The use of multimodal readout mechanisms next to label-free real-time monitoring of biomolecular interactions can provide valuable insight into surface-based reaction mechanisms. To this end, the combination of an electrolyte-gated field-effect transistor (EG-FET) with a fiber optic-coupled surface plasmon resonance (FO-SPR) probe serving as gate electrode has been investigated to deconvolute surface mass and charge density variations associated to surface reactions. However, applying an electrochemical potential on such gold-coated FO-SPR gate electrodes can induce gradual morphological changes of the thin gold film, leading to an irreversible blue-shift of the SPR wavelength and a substantial signal drift. We show that mild annealing leads to optical and electronic signal stabilization (20-fold lower signal drift than as-sputtered fiber optic gates) and improved overall analytical performance characteristics. The thermal treatment prevents morphological changes of the thin gold-film occurring during operation, hence providing reliable and stable data immediately upon gate voltage application. Thus, the readout output of both transducing principles, the optical FO-SPR and electronic EG-FET, stays constant throughout the whole sensing time-window and the long-term effect of thermal treatment is also improved, providing stable signals even after 1 year of storage. Annealing should therefore be considered a necessary modification for applying fiber optic gate electrodes in real-time multimodal investigations of surface reactions at the solid-liquid interface."}],"department":[{"_id":"MaIb"}],"volume":11,"publisher":"Frontiers","date_created":"2023-08-06T22:01:11Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication_status":"published","external_id":{"isi":["001038636400001"]},"_id":"13968","scopus_import":"1","month":"07","date_published":"2023-07-14T00:00:00Z","intvolume":"        11","file":[{"access_level":"open_access","creator":"dernst","file_size":2421758,"date_created":"2023-08-07T07:48:11Z","file_name":"2023_FrontiersPhysics_Hasler.pdf","success":1,"content_type":"application/pdf","checksum":"fb36dda665e57bab006a000bf0faacd5","relation":"main_file","date_updated":"2023-08-07T07:48:11Z","file_id":"13978"}],"oa":1,"day":"14","doi":"10.3389/fphy.2023.1202132","year":"2023","acknowledgement":"This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement No. 813863–BORGES. We further thank the office of the Federal Government of Lower Austria, K3-Group–Culture, Science and Education, for their financial support as part of the project “Responsive Wound Dressing”. We gratefully acknowledge the financial support from the Austrian Research Promotion Agency (FFG; 888067).\r\nWe thank the Electron Microscopy Facility at IST Austria for their support with sputter coating the FO tips and Bernhard Pichler from AIT for software development to facilitate data evaluation.","article_type":"original","publication_identifier":{"eissn":["2296-424X"]},"article_number":"1202132","acknowledged_ssus":[{"_id":"EM-Fac"}],"isi":1,"publication":"Frontiers in Physics","ddc":["530"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_updated":"2025-03-11T08:00:41Z","related_material":{"record":[{"id":"19308","relation":"research_data","status":"public"}]},"title":"Optical and electronic signal stabilization of plasmonic fiber optic gate electrodes: Towards improved real-time dual-mode biosensing","author":[{"first_name":"Roger","last_name":"Hasler","full_name":"Hasler, Roger"},{"full_name":"Steger-Polt, Marie Helene","last_name":"Steger-Polt","first_name":"Marie Helene"},{"first_name":"Ciril","last_name":"Reiner-Rozman","full_name":"Reiner-Rozman, Ciril"},{"full_name":"Fossati, Stefan","last_name":"Fossati","first_name":"Stefan"},{"first_name":"Seungho","id":"BB243B88-D767-11E9-B658-BC13E6697425","full_name":"Lee, Seungho","last_name":"Lee","orcid":"0000-0002-6962-8598"},{"first_name":"Patrik","full_name":"Aspermair, Patrik","last_name":"Aspermair"},{"first_name":"Christoph","full_name":"Kleber, Christoph","last_name":"Kleber"},{"first_name":"Maria","full_name":"Ibáñez, Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843"},{"full_name":"Dostalek, Jakub","last_name":"Dostalek","first_name":"Jakub"},{"first_name":"Wolfgang","last_name":"Knoll","full_name":"Knoll, Wolfgang"}],"article_processing_charge":"Yes","has_accepted_license":"1","file_date_updated":"2023-08-07T07:48:11Z","status":"public","language":[{"iso":"eng"}]},{"status":"public","language":[{"iso":"eng"}],"file_date_updated":"2023-08-07T08:00:48Z","has_accepted_license":"1","article_processing_charge":"Yes","title":"Approximating the bundled crossing number","author":[{"id":"3207FDC6-F248-11E8-B48F-1D18A9856A87","full_name":"Arroyo Guevara, Alan M","last_name":"Arroyo Guevara","orcid":"0000-0003-2401-8670","first_name":"Alan M"},{"first_name":"Stefan","full_name":"Felsner, Stefan","last_name":"Felsner"}],"page":"433-457","date_updated":"2025-09-10T09:35:55Z","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"11185"}]},"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","call_identifier":"H2020"}],"ddc":["510"],"arxiv":1,"publication":"Journal of Graph Algorithms and Applications","ec_funded":1,"article_type":"original","year":"2023","acknowledgement":"This work was initiated during the Workshop on Geometric Graphs in November 2019 in Strobl, Austria. We would like to thank Oswin Aichholzer, Fabian Klute, Man-Kwun Chiu, Martin Balko, Pavel Valtr for their avid discussions during the workshop. The first author has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sk lodowska-Curie grant agreement No 754411. The second author has been supported by the German Research Foundation DFG Project FE 340/12-1. An extended abstract of this paper has been published in the proceedings of WALCOM 2022 in the Springer LNCS series, vol. 13174, pages 383–395.","publication_identifier":{"issn":["1526-1719"]},"day":"01","doi":"10.7155/jgaa.00629","file":[{"content_type":"application/pdf","checksum":"9c30d2b8e324cc1c904f2aeec92013a3","relation":"main_file","date_updated":"2023-08-07T08:00:48Z","file_id":"13979","access_level":"open_access","creator":"dernst","file_size":865774,"success":1,"date_created":"2023-08-07T08:00:48Z","file_name":"2023_JourGraphAlgorithms_Arroyo.pdf"}],"oa":1,"intvolume":"        27","date_published":"2023-07-01T00:00:00Z","month":"07","scopus_import":"1","issue":"6","_id":"13969","external_id":{"arxiv":["2109.14892"]},"publication_status":"published","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_created":"2023-08-06T22:01:11Z","publisher":"Brown University","corr_author":"1","volume":27,"department":[{"_id":"UlWa"}],"type":"journal_article","abstract":[{"lang":"eng","text":"Bundling crossings is a strategy which can enhance the readability\r\nof graph drawings. In this paper we consider good drawings, i.e., we require that\r\nany two edges have at most one common point which can be a common vertex or a\r\ncrossing. Our main result is that there is a polynomial-time algorithm to compute an\r\n8-approximation of the bundled crossing number of a good drawing with no toothed\r\nhole. In general the number of toothed holes has to be added to the 8-approximation.\r\nIn the special case of circular drawings the approximation factor is 8, this improves\r\nupon the 10-approximation of Fink et al. [14]. Our approach also works with the same\r\napproximation factor for families of pseudosegments, i.e., curves intersecting at most\r\nonce. We also show how to compute a 9/2-approximation when the intersection graph of\r\nthe pseudosegments is bipartite and has no toothed hole."}],"citation":{"ista":"Arroyo Guevara AM, Felsner S. 2023. Approximating the bundled crossing number. Journal of Graph Algorithms and Applications. 27(6), 433–457.","chicago":"Arroyo Guevara, Alan M, and Stefan Felsner. “Approximating the Bundled Crossing Number.” <i>Journal of Graph Algorithms and Applications</i>. Brown University, 2023. <a href=\"https://doi.org/10.7155/jgaa.00629\">https://doi.org/10.7155/jgaa.00629</a>.","mla":"Arroyo Guevara, Alan M., and Stefan Felsner. “Approximating the Bundled Crossing Number.” <i>Journal of Graph Algorithms and Applications</i>, vol. 27, no. 6, Brown University, 2023, pp. 433–57, doi:<a href=\"https://doi.org/10.7155/jgaa.00629\">10.7155/jgaa.00629</a>.","ieee":"A. M. Arroyo Guevara and S. Felsner, “Approximating the bundled crossing number,” <i>Journal of Graph Algorithms and Applications</i>, vol. 27, no. 6. Brown University, pp. 433–457, 2023.","apa":"Arroyo Guevara, A. M., &#38; Felsner, S. (2023). Approximating the bundled crossing number. <i>Journal of Graph Algorithms and Applications</i>. Brown University. <a href=\"https://doi.org/10.7155/jgaa.00629\">https://doi.org/10.7155/jgaa.00629</a>","ama":"Arroyo Guevara AM, Felsner S. Approximating the bundled crossing number. <i>Journal of Graph Algorithms and Applications</i>. 2023;27(6):433-457. doi:<a href=\"https://doi.org/10.7155/jgaa.00629\">10.7155/jgaa.00629</a>","short":"A.M. Arroyo Guevara, S. Felsner, Journal of Graph Algorithms and Applications 27 (2023) 433–457."},"quality_controlled":"1"}]