[{"title":"Redshifted sodium transient near exoplanet transit","article_type":"original","publisher":"IOP Publishing","_id":"18306","supplementarymaterial":"no","oa":1,"OA_place":"publisher","date_published":"2024-10-01T00:00:00Z","das_tickbox":"1","volume":973,"month":"10","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","DOAJ_listed":"1","publication":"Astrophysical Journal Letters","citation":{"chicago":"Oza, Apurva V., Julia V. Seidel, H. Jens Hoeijmakers, Athira Unni, Aurora Y. Kesseli, Carl A. Schmidt, Thirupathi Sivarani, et al. “Redshifted Sodium Transient near Exoplanet Transit.” <i>Astrophysical Journal Letters</i>. IOP Publishing, 2024. <a href=\"https://doi.org/10.3847/2041-8213/ad6b29\">https://doi.org/10.3847/2041-8213/ad6b29</a>.","ieee":"A. V. Oza <i>et al.</i>, “Redshifted sodium transient near exoplanet transit,” <i>Astrophysical Journal Letters</i>, vol. 973, no. 2. IOP Publishing, 2024.","ista":"Oza AV, Seidel JV, Hoeijmakers HJ, Unni A, Kesseli AY, Schmidt CA, Sivarani T, Bello-Arufe A, Gebek A, Meyer Zu Westram M, Sousa SG, Lopes RMC, Hu R, De Kleer K, Fisher C, Charnoz S, Baker AD, Halverson SP, Schneider NM, Psaridi A, Wyttenbach A, Torres Rodriguez S, Bhatnagar I, Johnson RE. 2024. Redshifted sodium transient near exoplanet transit. Astrophysical Journal Letters. 973(2), L53.","short":"A.V. Oza, J.V. Seidel, H.J. Hoeijmakers, A. Unni, A.Y. Kesseli, C.A. Schmidt, T. Sivarani, A. Bello-Arufe, A. Gebek, M. Meyer Zu Westram, S.G. Sousa, R.M.C. Lopes, R. Hu, K. De Kleer, C. Fisher, S. Charnoz, A.D. Baker, S.P. Halverson, N.M. Schneider, A. Psaridi, A. Wyttenbach, S. Torres Rodriguez, I. Bhatnagar, R.E. Johnson, Astrophysical Journal Letters 973 (2024).","ama":"Oza AV, Seidel JV, Hoeijmakers HJ, et al. Redshifted sodium transient near exoplanet transit. <i>Astrophysical Journal Letters</i>. 2024;973(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ad6b29\">10.3847/2041-8213/ad6b29</a>","mla":"Oza, Apurva V., et al. “Redshifted Sodium Transient near Exoplanet Transit.” <i>Astrophysical Journal Letters</i>, vol. 973, no. 2, L53, IOP Publishing, 2024, doi:<a href=\"https://doi.org/10.3847/2041-8213/ad6b29\">10.3847/2041-8213/ad6b29</a>.","apa":"Oza, A. V., Seidel, J. V., Hoeijmakers, H. J., Unni, A., Kesseli, A. Y., Schmidt, C. A., … Johnson, R. E. (2024). Redshifted sodium transient near exoplanet transit. <i>Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ad6b29\">https://doi.org/10.3847/2041-8213/ad6b29</a>"},"intvolume":"       973","doi":"10.3847/2041-8213/ad6b29","date_created":"2024-10-13T22:01:49Z","article_processing_charge":"Yes","publication_status":"published","publication_identifier":{"issn":["2041-8205"],"eissn":["2041-8213"]},"oa_version":"Published Version","file_date_updated":"2024-10-21T11:05:11Z","article_number":"L53","external_id":{"isi":["001322169500001"],"arxiv":["2409.19844"]},"author":[{"last_name":"Oza","full_name":"Oza, Apurva V.","first_name":"Apurva V."},{"full_name":"Seidel, Julia V.","first_name":"Julia V.","last_name":"Seidel"},{"full_name":"Hoeijmakers, H. Jens","first_name":"H. Jens","last_name":"Hoeijmakers"},{"last_name":"Unni","first_name":"Athira","full_name":"Unni, Athira"},{"last_name":"Kesseli","full_name":"Kesseli, Aurora Y.","first_name":"Aurora Y."},{"last_name":"Schmidt","full_name":"Schmidt, Carl A.","first_name":"Carl A."},{"first_name":"Thirupathi","full_name":"Sivarani, Thirupathi","last_name":"Sivarani"},{"last_name":"Bello-Arufe","first_name":"Aaron","full_name":"Bello-Arufe, Aaron"},{"first_name":"Andrea","full_name":"Gebek, Andrea","last_name":"Gebek"},{"last_name":"Meyer Zu Westram","full_name":"Meyer Zu Westram, Moritz","first_name":"Moritz"},{"last_name":"Sousa","first_name":"Sérgio G.","full_name":"Sousa, Sérgio G."},{"last_name":"Lopes","full_name":"Lopes, Rosaly M.C.","first_name":"Rosaly M.C."},{"full_name":"Hu, Renyu","first_name":"Renyu","last_name":"Hu"},{"last_name":"De Kleer","first_name":"Katherine","full_name":"De Kleer, Katherine"},{"first_name":"Chloe","full_name":"Fisher, Chloe","last_name":"Fisher"},{"last_name":"Charnoz","first_name":"Sébastien","full_name":"Charnoz, Sébastien"},{"last_name":"Baker","full_name":"Baker, Ashley D.","first_name":"Ashley D."},{"last_name":"Halverson","full_name":"Halverson, Samuel P.","first_name":"Samuel P."},{"first_name":"Nick M.","full_name":"Schneider, Nick M.","last_name":"Schneider"},{"last_name":"Psaridi","first_name":"Angelica","full_name":"Psaridi, Angelica"},{"last_name":"Wyttenbach","full_name":"Wyttenbach, Aurélien","first_name":"Aurélien"},{"orcid":"0000-0002-3150-8988","id":"a8df4360-4328-11ee-8f1a-e502d0c83fc2","first_name":"Santiago","full_name":"Torres Rodriguez, Santiago","last_name":"Torres Rodriguez"},{"full_name":"Bhatnagar, Ishita","first_name":"Ishita","last_name":"Bhatnagar"},{"full_name":"Johnson, Robert E.","first_name":"Robert E.","last_name":"Johnson"}],"abstract":[{"text":"Neutral sodium (Na i) is an alkali metal with a favorable absorption cross section such that tenuous gases are easily illuminated at select transiting exoplanet systems. We examine both the time-averaged and time-series alkali spectral flux individually, over 4 nights at a hot Saturn system on a ∼2.8 day orbit about a Sun-like star WASP-49 A. Very Large Telescope/ESPRESSO observations are analyzed, providing new constraints. We recover the previously confirmed residual sodium flux uniquely when averaged, whereas night-to-night Na i varies by more than an order of magnitude. On HARPS/3.6 m Epoch II, we report a Doppler redshift at vΓ,NaD = + 9.7 ± 1.6 km s−1 with respect to the planet's rest frame. Upon examining the lightcurves, we confirm night-to-night variability, on the order of ∼1%–4% in NaD, rarely coinciding with exoplanet transit, not readily explained by stellar activity, starspots, tellurics, or the interstellar medium. Coincident with the ∼+10 km s−1 Doppler redshift, we detect a transient sodium absorption event dFNaD/F⋆ = 3.6% ± 1% at a relative difference of ΔFNaD(t) ∼ 4.4% ± 1%, lasting ΔtNaD ≳ 40 minutes. Since exoplanetary alkali signatures are blueshifted due to the natural vector of radiation pressure, estimated here at roughly ∼−5.7 km s−1, the radial velocity is rather at +15.4 km s−1, far larger than any known exoplanet system. Given that the redshift magnitude vΓ is in between the Roche limit and dynamically stable satellite orbits, the transient sodium may be a putative indication of a natural satellite orbiting WASP-49 A b.","lang":"eng"}],"ddc":["520"],"scopus_import":"1","date_updated":"2026-10-16T08:52:49Z","day":"01","fulldoi":"https://doi.org/10.3847/2041-8213/ad6b29","issue":"2","status":"public","has_accepted_license":"1","type":"journal_article","dataavailabilitystatement":"ESO data is available publicly on ESO’s science archive facility at archive.eso.org/eso/eso_archive_main.html.","department":[{"_id":"LiBu"}],"year":"2024","file":[{"file_size":1249747,"date_created":"2024-10-21T11:05:11Z","file_id":"18456","access_level":"open_access","checksum":"23eea2a6a0519694a84998957ad7b7fb","success":1,"content_type":"application/pdf","file_name":"2024_AstrophysicalJourn_Oza.pdf","relation":"main_file","creator":"dernst","date_updated":"2024-10-21T11:05:11Z"}],"arxiv":1,"quality_controlled":"1","OA_type":"gold","researchdata_availability":"yes","acknowledgement":"The research described in this Letter was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics Space Administration, © 2024. California Institute of Technology. Government sponsorship acknowledged. A.V.O. and J.V.S. thank M. Lendl for constraints and discussions on the mass of WASP-49 A b. S.G.S acknowledges the support from FCT through Investigador FCT contract nr. CEECIND/00826/2018 and POPH/FSE (EC)."},{"OA_type":"hybrid","researchdata_availability":"yes","quality_controlled":"1","acknowledgement":"The authors thank S. Mathis, L. Barrault, S. Torres, A. Cristea, and K. M. Smith for very useful discussions. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curíe grant agreement No 101034413. The authors thank the anonymous referee for valuable comments and suggestions to improve the manuscript.","file":[{"creator":"dernst","content_type":"application/pdf","relation":"main_file","file_name":"2024_AstronomyAstrophysics_Das.pdf","date_updated":"2024-11-11T09:01:11Z","date_created":"2024-11-11T09:01:11Z","access_level":"open_access","file_id":"18534","checksum":"d43bbe6ed8ce4512e65e2d0d87070cf6","file_size":5306256,"success":1}],"year":"2024","department":[{"_id":"LiBu"}],"dataavailabilitystatement":"The MESA inlist file is available at https://doi.org/10.5281/zenodo.12804810","arxiv":1,"ec_funded":1,"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"type":"journal_article","has_accepted_license":"1","status":"public","scopus_import":"1","ddc":["520"],"fulldoi":"https://doi.org/10.1051/0004-6361/202450918","date_updated":"2026-10-16T08:53:44Z","day":"01","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"oa_version":"Published Version","date_created":"2024-11-10T23:02:00Z","doi":"10.1051/0004-6361/202450918","article_processing_charge":"No","publication_status":"published","abstract":[{"text":"The recent measurement of magnetic field strength inside the radiative interior of red giant stars has opened the way toward full 3D characterization of the geometry of stable large-scale magnetic fields. However, current measurements, which are limited to dipolar (ℓ = 1) mixed modes, do not properly constrain the topology of magnetic fields due to degeneracies on the observed magnetic field signature on such ℓ = 1 mode frequencies. Efforts focused toward unambiguous detections of magnetic field configurations are now key to better understand angular momentum transport in stars. We investigated the detectability of complex magnetic field topologies (such as the ones observed at the surface of stars with a radiative envelope with spectropolarimetry) inside the radiative interior of red giants. We focused on a field composed of a combination of a dipole and a quadrupole (quadrudipole) and on an offset field. We explored the potential of probing such magnetic field topologies from a combined measurement of magnetic signatures on ℓ = 1 and quadrupolar (ℓ = 2) mixed mode oscillation frequencies. We first derived the asymptotic theoretical formalism for computing the asymmetric signature in the frequency pattern for ℓ = 2 modes due to a quadrudipole magnetic field. To access asymmetry parameters for more complex magnetic field topologies, we numerically performed a grid search over the parameter space to map the degeneracy of the signatures of given topologies. We demonstrate the crucial role played by ℓ = 2 mixed modes in accessing internal magnetic fields with a quadrupolar component. The degeneracy of the quadrudipole compared to pure dipolar fields is lifted when considering magnetic asymmetries in both ℓ = 1 and ℓ = 2 mode frequencies. In addition to the analytical derivation for the quadrudipole, we present the prospect for complex magnetic field inversions using magnetic sensitivity kernels from standard perturbation analysis for forward modeling. Using this method, we explored the detectability of offset magnetic fields from ℓ = 1 and ℓ = 2 frequencies and demonstrate that offset fields may be mistaken for weak and centered magnetic fields, resulting in underestimating the magnetic field strength in stellar cores. We emphasize the need to characterize ℓ = 2 mixed-mode frequencies, (along with the currently characterized ℓ = 1 mixed modes), to unveil the higher-order components of the geometry of buried magnetic fields and to better constrain angular momentum transport inside stars.","lang":"eng"}],"author":[{"last_name":"Das","orcid":"0000-0003-0896-7972","id":"9ce7c423-dacf-11ed-8942-e09c6cb27149","full_name":"Das, Srijan B","first_name":"Srijan B"},{"last_name":"Einramhof","full_name":"Einramhof, Lukas","first_name":"Lukas","id":"f1497a1a-72ef-11ef-b75a-fd877bbf6e8c"},{"last_name":"Bugnet","id":"d9edb345-f866-11ec-9b37-d119b5234501","orcid":"0000-0003-0142-4000","first_name":"Lisa Annabelle","full_name":"Bugnet, Lisa Annabelle"}],"external_id":{"isi":["001336485200015"],"arxiv":["2405.20133"]},"article_number":"A217","file_date_updated":"2024-11-11T09:01:11Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","corr_author":"1","isi":1,"related_material":{"record":[{"id":"22802","status":"public","relation":"research_data"}]},"language":[{"iso":"eng"}],"intvolume":"       690","citation":{"apa":"Das, S. B., Einramhof, L., &#38; Bugnet, L. A. (2024). Unveiling complex magnetic field configurations in red giant stars. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202450918\">https://doi.org/10.1051/0004-6361/202450918</a>","mla":"Das, Srijan B., et al. “Unveiling Complex Magnetic Field Configurations in Red Giant Stars.” <i>Astronomy &#38; Astrophysics</i>, vol. 690, A217, EDP Sciences, 2024, doi:<a href=\"https://doi.org/10.1051/0004-6361/202450918\">10.1051/0004-6361/202450918</a>.","ieee":"S. B. Das, L. Einramhof, and L. A. Bugnet, “Unveiling complex magnetic field configurations in red giant stars,” <i>Astronomy &#38; Astrophysics</i>, vol. 690. EDP Sciences, 2024.","chicago":"Das, Srijan B, Lukas Einramhof, and Lisa Annabelle Bugnet. “Unveiling Complex Magnetic Field Configurations in Red Giant Stars.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2024. <a href=\"https://doi.org/10.1051/0004-6361/202450918\">https://doi.org/10.1051/0004-6361/202450918</a>.","ista":"Das SB, Einramhof L, Bugnet LA. 2024. Unveiling complex magnetic field configurations in red giant stars. Astronomy &#38; Astrophysics. 690, A217.","short":"S.B. Das, L. Einramhof, L.A. Bugnet, Astronomy &#38; Astrophysics 690 (2024).","ama":"Das SB, Einramhof L, Bugnet LA. Unveiling complex magnetic field configurations in red giant stars. <i>Astronomy &#38; Astrophysics</i>. 2024;690. doi:<a href=\"https://doi.org/10.1051/0004-6361/202450918\">10.1051/0004-6361/202450918</a>"},"publication":"Astronomy & Astrophysics","month":"10","volume":690,"OA_place":"publisher","date_published":"2024-10-01T00:00:00Z","das_tickbox":"1","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"original","title":"Unveiling complex magnetic field configurations in red giant stars","_id":"18528","supplementarymaterial":"yes","publisher":"EDP Sciences"},{"publisher":"National Academy of Sciences","supplementarymaterial":"yes","_id":"15335","title":"Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges","article_type":"original","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"date_published":"2024-04-09T00:00:00Z","das_tickbox":"1","oa":1,"volume":121,"month":"04","intvolume":"       121","citation":{"short":"S.K. Godavarthi, M. Hiramoto, Y. Ignatyev, J.B. Levin, H.Q. Li, M. Pratelli, J. Borchardt, C. Czajkowski, L.N. Borodinsky, L.B. Sweeney, H.T. Cline, N.C. Spitzer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","ama":"Godavarthi SK, Hiramoto M, Ignatyev Y, et al. Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(15). doi:<a href=\"https://doi.org/10.1073/pnas.2318041121\">10.1073/pnas.2318041121</a>","chicago":"Godavarthi, Swetha K., Masaki Hiramoto, Yuri Ignatyev, Jacqueline B. Levin, Hui Quan Li, Marta Pratelli, Jennifer Borchardt, et al. “Postsynaptic Receptors Regulate Presynaptic Transmitter Stability through Transsynaptic Bridges.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2318041121\">https://doi.org/10.1073/pnas.2318041121</a>.","ieee":"S. K. Godavarthi <i>et al.</i>, “Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 15. National Academy of Sciences, 2024.","ista":"Godavarthi SK, Hiramoto M, Ignatyev Y, Levin JB, Li HQ, Pratelli M, Borchardt J, Czajkowski C, Borodinsky LN, Sweeney LB, Cline HT, Spitzer NC. 2024. Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges. Proceedings of the National Academy of Sciences of the United States of America. 121(15), e2318041121.","mla":"Godavarthi, Swetha K., et al. “Postsynaptic Receptors Regulate Presynaptic Transmitter Stability through Transsynaptic Bridges.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 15, e2318041121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2318041121\">10.1073/pnas.2318041121</a>.","apa":"Godavarthi, S. K., Hiramoto, M., Ignatyev, Y., Levin, J. B., Li, H. Q., Pratelli, M., … Spitzer, N. C. (2024). Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2318041121\">https://doi.org/10.1073/pnas.2318041121</a>"},"publication":"Proceedings of the National Academy of Sciences of the United States of America","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"article_number":"e2318041121","file_date_updated":"2024-04-23T06:53:14Z","abstract":[{"lang":"eng","text":"Stable matching of neurotransmitters with their receptors is fundamental to synapse function and reliable communication in neural circuits. Presynaptic neurotransmitters regulate the stabilization of postsynaptic transmitter receptors. Whether postsynaptic receptors regulate stabilization of presynaptic transmitters has received less attention. Here, we show that blockade of endogenous postsynaptic acetylcholine receptors (AChR) at the neuromuscular junction destabilizes the cholinergic phenotype in motor neurons and stabilizes an earlier, developmentally transient glutamatergic phenotype. Further, expression of exogenous postsynaptic gamma-aminobutyric acid type A receptors (GABAA receptors) in muscle cells stabilizes an earlier, developmentally transient GABAergic motor neuron phenotype. Both AChR and GABAA receptors are linked to presynaptic neurons through transsynaptic bridges. Knockdown of specific components of these transsynaptic bridges prevents stabilization of the cholinergic or GABAergic phenotypes. Bidirectional communication can enforce a match between transmitter and receptor and ensure the fidelity of synaptic transmission. Our findings suggest a potential role of dysfunctional transmitter receptors in neurological disorders that involve the loss of the presynaptic transmitter."}],"author":[{"full_name":"Godavarthi, Swetha K.","first_name":"Swetha K.","last_name":"Godavarthi"},{"last_name":"Hiramoto","full_name":"Hiramoto, Masaki","first_name":"Masaki"},{"full_name":"Ignatyev, Yuri","first_name":"Yuri","last_name":"Ignatyev"},{"full_name":"Levin, Jacqueline B.","first_name":"Jacqueline B.","last_name":"Levin"},{"full_name":"Li, Hui Quan","first_name":"Hui Quan","last_name":"Li"},{"last_name":"Pratelli","full_name":"Pratelli, Marta","first_name":"Marta"},{"last_name":"Borchardt","full_name":"Borchardt, Jennifer","first_name":"Jennifer"},{"full_name":"Czajkowski, Cynthia","first_name":"Cynthia","last_name":"Czajkowski"},{"last_name":"Borodinsky","first_name":"Laura N.","full_name":"Borodinsky, Laura N."},{"last_name":"Sweeney","orcid":"0000-0001-9242-5601","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","first_name":"Lora Beatrice Jaeger","full_name":"Sweeney, Lora Beatrice Jaeger"},{"first_name":"Hollis T.","full_name":"Cline, Hollis T.","last_name":"Cline"},{"last_name":"Spitzer","full_name":"Spitzer, Nicholas C.","first_name":"Nicholas C."}],"external_id":{"pmid":["38568976"],"isi":["001243892800004"]},"doi":"10.1073/pnas.2318041121","date_created":"2024-04-21T22:00:53Z","publication_status":"published","article_processing_charge":"Yes (in subscription journal)","oa_version":"Published Version","publication_identifier":{"eissn":["1091-6490"]},"fulldoi":"https://doi.org/10.1073/pnas.2318041121","pmid":1,"day":"09","date_updated":"2026-10-16T08:57:16Z","ddc":["570"],"scopus_import":"1","has_accepted_license":"1","status":"public","type":"journal_article","issue":"15","department":[{"_id":"LoSw"}],"dataavailabilitystatement":"All data are included in the manuscript and/or supporting information.","file":[{"date_updated":"2024-04-23T06:53:14Z","creator":"dernst","file_name":"2024_PNAS_Godavarthi.pdf","relation":"main_file","content_type":"application/pdf","success":1,"checksum":"f3b4ffad4ef3d1c443414edf0cd2392c","access_level":"open_access","file_id":"15340","date_created":"2024-04-23T06:53:14Z","file_size":16187094}],"year":"2024","acknowledgement":"We  thank  all  members  of  the  Spitzer  laboratory  for  discussions  and  critical  feedback;  K.  Marek  for  discussions  of  acknowledgment  signals; I. Gregor and R. Aricescu for discussions of receptor pharmacology and transsynaptic  bridges;  C.  Kintner  for  advice  on  Xenopus  blastomere  lineage;  A.  Ray and E. Park for guidance on miniature analysis; A. Glavis- Bloom, S.U. Choi, S. Atkins, M. Gupta, and S. Malladi for technical assistance; and D. K. Berg and L. R. Squire for comments on the manuscript. This work was supported by NSF 2051555 and the Overland Foundation. Microscopy for five- channel imaging utilized the UCSD School of Medicine Microscopy Core, supported by NIH grant NS047101.","researchdata_availability":"yes (supplementary data)","quality_controlled":"1"},{"article_processing_charge":"No","date_created":"2024-10-13T22:01:49Z","publication_status":"published","doi":"10.1523/JNEUROSCI.1238-24.2024","publication_identifier":{"eissn":["1529-2401"]},"oa_version":"Published Version","article_number":"e1238242024","external_id":{"pmid":["39358025"],"isi":["001335212200016"]},"abstract":[{"text":"Motor circuits represent the main output of the central nervous system and produce dynamic behaviors ranging from relatively simple rhythmic activities like swimming in fish and breathing in mammals to highly sophisticated dexterous movements in humans. Despite decades of research, the development and function of motor circuits remain poorly understood. Breakthroughs in the field recently provided new tools and tractable model systems that set the stage to discover the molecular mechanisms and circuit logic underlying motor control. Here, we describe recent advances from both vertebrate (mouse, frog) and invertebrate (nematode, fruit fly) systems on cellular and molecular mechanisms that enable motor circuits to develop and function and highlight conserved and divergent mechanisms necessary for motor circuit development.","lang":"eng"}],"author":[{"first_name":"Paschalis","full_name":"Kratsios, Paschalis","last_name":"Kratsios"},{"last_name":"Zampieri","first_name":"Niccolò","full_name":"Zampieri, Niccolò"},{"last_name":"Carrillo","first_name":"Robert","full_name":"Carrillo, Robert"},{"first_name":"Kota","full_name":"Mizumoto, Kota","last_name":"Mizumoto"},{"last_name":"Sweeney","first_name":"Lora Beatrice Jaeger","full_name":"Sweeney, Lora Beatrice Jaeger","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","orcid":"0000-0001-9242-5601"},{"first_name":"Polyxeni","full_name":"Philippidou, Polyxeni","last_name":"Philippidou"}],"language":[{"iso":"eng"}],"isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"The Journal of Neuroscience","citation":{"ama":"Kratsios P, Zampieri N, Carrillo R, Mizumoto K, Sweeney LB, Philippidou P. Molecular and cellular mechanisms of motor circuit development. <i>The Journal of Neuroscience</i>. 2024;44(40). doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1238-24.2024\">10.1523/JNEUROSCI.1238-24.2024</a>","short":"P. Kratsios, N. Zampieri, R. Carrillo, K. Mizumoto, L.B. Sweeney, P. Philippidou, The Journal of Neuroscience 44 (2024).","ieee":"P. Kratsios, N. Zampieri, R. Carrillo, K. Mizumoto, L. B. Sweeney, and P. Philippidou, “Molecular and cellular mechanisms of motor circuit development,” <i>The Journal of Neuroscience</i>, vol. 44, no. 40. Society for Neuroscience, 2024.","chicago":"Kratsios, Paschalis, Niccolò Zampieri, Robert Carrillo, Kota Mizumoto, Lora B. Sweeney, and Polyxeni Philippidou. “Molecular and Cellular Mechanisms of Motor Circuit Development.” <i>The Journal of Neuroscience</i>. Society for Neuroscience, 2024. <a href=\"https://doi.org/10.1523/JNEUROSCI.1238-24.2024\">https://doi.org/10.1523/JNEUROSCI.1238-24.2024</a>.","ista":"Kratsios P, Zampieri N, Carrillo R, Mizumoto K, Sweeney LB, Philippidou P. 2024. Molecular and cellular mechanisms of motor circuit development. The Journal of Neuroscience. 44(40), e1238242024.","mla":"Kratsios, Paschalis, et al. “Molecular and Cellular Mechanisms of Motor Circuit Development.” <i>The Journal of Neuroscience</i>, vol. 44, no. 40, e1238242024, Society for Neuroscience, 2024, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1238-24.2024\">10.1523/JNEUROSCI.1238-24.2024</a>.","apa":"Kratsios, P., Zampieri, N., Carrillo, R., Mizumoto, K., Sweeney, L. B., &#38; Philippidou, P. (2024). Molecular and cellular mechanisms of motor circuit development. <i>The Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.1238-24.2024\">https://doi.org/10.1523/JNEUROSCI.1238-24.2024</a>"},"intvolume":"        44","oa":1,"date_published":"2024-10-02T00:00:00Z","das_tickbox":"0","OA_place":"publisher","volume":44,"month":"10","OA_embargo":"6 months","title":"Molecular and cellular mechanisms of motor circuit development","article_type":"original","main_file_link":[{"url":"https://doi.org/10.1523/JNEUROSCI.1238-24.2024","open_access":"1"}],"publisher":"Society for Neuroscience","supplementarymaterial":"no","_id":"18305","quality_controlled":"1","researchdata_availability":"no","OA_type":"hybrid","acknowledgement":"Work in the authors’ labs is funded by the Helmholtz Association (N.Z.), National Institute of Neurological Disorders and Stroke (NINDS) R01NS116365 (P.K.), NINDS R01NS123439 and National Science Foundation IOS-2048080 (R.C.), NINDS R01NS114510 (P.P.), Natural Sciences and Engineering Research Council of Canada RGPIN-2021-03154 (K.M.) and Horizon Europe European Research Council Starting Grant Number 101041551 (L.B.S.). P.P. is the Weidenthal Family Designated Professor in Career Development.","department":[{"_id":"LoSw"}],"year":"2024","project":[{"grant_number":"101041551","name":"Development and Evolution of Tetrapod Motor Circuits","_id":"ebb66355-77a9-11ec-83b8-b8ac210a4dae"}],"issue":"40","status":"public","has_accepted_license":"1","type":"journal_article","ddc":["570"],"scopus_import":"1","day":"02","date_updated":"2026-10-16T08:57:51Z","pmid":1,"fulldoi":"https://doi.org/10.1523/JNEUROSCI.1238-24.2024"},{"author":[{"first_name":"Chris S.","full_name":"Hanson, Chris S.","last_name":"Hanson"},{"id":"9ce7c423-dacf-11ed-8942-e09c6cb27149","orcid":"0000-0003-0896-7972","full_name":"Das, Srijan B","first_name":"Srijan B","last_name":"Das"},{"full_name":"Mani, Prasad","first_name":"Prasad","last_name":"Mani"},{"last_name":"Hanasoge","full_name":"Hanasoge, Shravan","first_name":"Shravan"},{"last_name":"Sreenivasan","full_name":"Sreenivasan, Katepalli R.","first_name":"Katepalli R."}],"abstract":[{"text":"Supergranules, which are solar flow features with a lateral scale of 30,000–40,000 km and a lifetime of ~24 h, form a prominent component of the Sun’s convective spectrum. However, their internal flows, which can be probed only by helioseismology, are not well understood. We analyse dopplergrams recorded by the Solar Dynamics Observatory satellite to identify and characterize ~23,000 supergranules. We find that the vertical flows peak at a depth of ~10,000 km, and remain invariant over the full range of lateral supergranular scales, contrary to numerical predictions. We also infer that, within the local seismic resolution (≳5,000 km), downflows are ~40% weaker than upflows, indicating an apparent mass-flux imbalance. This may imply that the descending flows also comprise plumes, which maintain the mass balance but are simply too small to be detected by seismic waves. These results challenge the widely used mixing-length description of solar convection.","lang":"eng"}],"external_id":{"isi":["001254181700001"]},"publication_status":"published","article_processing_charge":"No","doi":"10.1038/s41550-024-02304-w","date_created":"2024-06-30T22:01:05Z","oa_version":"None","publication_identifier":{"eissn":["2397-3366"]},"intvolume":"         8","citation":{"mla":"Hanson, Chris S., et al. “Supergranular-Scale Solar Convection Not Explained by Mixing-Length Theory.” <i>Nature Astronomy</i>, vol. 8, Springer Nature, 2024, pp. 1088–101, doi:<a href=\"https://doi.org/10.1038/s41550-024-02304-w\">10.1038/s41550-024-02304-w</a>.","apa":"Hanson, C. S., Das, S. B., Mani, P., Hanasoge, S., &#38; Sreenivasan, K. R. (2024). Supergranular-scale solar convection not explained by mixing-length theory. <i>Nature Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41550-024-02304-w\">https://doi.org/10.1038/s41550-024-02304-w</a>","short":"C.S. Hanson, S.B. Das, P. Mani, S. Hanasoge, K.R. Sreenivasan, Nature Astronomy 8 (2024) 1088–1101.","ama":"Hanson CS, Das SB, Mani P, Hanasoge S, Sreenivasan KR. Supergranular-scale solar convection not explained by mixing-length theory. <i>Nature Astronomy</i>. 2024;8:1088-1101. doi:<a href=\"https://doi.org/10.1038/s41550-024-02304-w\">10.1038/s41550-024-02304-w</a>","chicago":"Hanson, Chris S., Srijan B Das, Prasad Mani, Shravan Hanasoge, and Katepalli R. Sreenivasan. “Supergranular-Scale Solar Convection Not Explained by Mixing-Length Theory.” <i>Nature Astronomy</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41550-024-02304-w\">https://doi.org/10.1038/s41550-024-02304-w</a>.","ieee":"C. S. Hanson, S. B. Das, P. Mani, S. Hanasoge, and K. R. Sreenivasan, “Supergranular-scale solar convection not explained by mixing-length theory,” <i>Nature Astronomy</i>, vol. 8. Springer Nature, pp. 1088–1101, 2024.","ista":"Hanson CS, Das SB, Mani P, Hanasoge S, Sreenivasan KR. 2024. Supergranular-scale solar convection not explained by mixing-length theory. Nature Astronomy. 8, 1088–1101."},"publication":"Nature Astronomy","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"das_tickbox":"1","date_published":"2024-09-01T00:00:00Z","volume":8,"month":"09","publisher":"Springer Nature","_id":"17189","supplementarymaterial":"yes","title":"Supergranular-scale solar convection not explained by mixing-length theory","article_type":"original","acknowledgement":"We thank F. J. Simons for the codes for computing Slepian functions,\r\nM. Rempel and R. Cameron for their insights into solar convection, J.\r\nW. Lord for the numerical simulations and J. Naranjo for his help with\r\nthe NYUAD NetDRMS system. This research was carried out with the\r\nHigh Performance Computing resources at NYUAD. The datasets were\r\nprepared in the data centre at the Center for Space Science of NYUAD.\r\nThis research is based upon work supported by Tamkeen under the\r\nNYUAD Research Institute (Grant Nos G1502 and CASS to C.S.H,\r\nS.H. and K.R.S.). S.H. acknowledges funding from the Department\r\nof Atomic Energy, India. K.R.S. and S.H. acknowledge support from\r\nthe Ofice of Sponsored Research of King Abdullah University of\r\nScience and Technology (Award No. OSR-CRG2020-4342). S.B.D.\r\nacknowledges funding from the Elisabeth H. and F. A. Dahlen Award\r\n2022 by the Department of Geosciences, Princeton University. S.B.D.\r\nalso acknowledges funding from the European Union’s Horizon 2020\r\nresearch and innovation programme under a Marie Skłodowska-Curie\r\ngrant (Grant Agreement No. 101034413). Some data products were\r\nprocessed and downloaded from the German Data Center for SDO,\r\nwhich is funded by the German Aerospace Center (DLR Grant No.\r\n500L1701).","OA_type":"closed access","researchdata_availability":"yes","quality_controlled":"1","department":[{"_id":"LiBu"}],"dataavailabilitystatement":"The HMI data are courtesy of NASA/SDO and the HMI Science Team. The HMI data are available from the Joint Science Operations Center export site http://jsoc.stanford.edu/. Due to the large volume of data, the mode-coupling products and kernels are available from the authors upon request. The numerical simulations are available upon request from M. Rempel.","year":"2024","status":"public","type":"journal_article","page":"1088-1101","ec_funded":1,"project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"fulldoi":"https://doi.org/10.1038/s41550-024-02304-w","date_updated":"2026-10-16T08:55:21Z","day":"01","scopus_import":"1"},{"OA_place":"repository","date_published":"2024-07-24T00:00:00Z","oa":1,"month":"07","status":"public","type":"research_data_reference","title":"MESA inlist file","ddc":["520"],"main_file_link":[{"url":"https://doi.org/10.5281/zenodo.12804810","open_access":"1"}],"publisher":"Institute of Science and Technology Austria","fulldoi":"https://doi.org/10.5281/zenodo.12804810","_id":"22802","day":"24","date_updated":"2026-10-16T08:53:43Z","article_processing_charge":"No","date_created":"2026-09-04T09:42:23Z","doi":"10.5281/zenodo.12804810","OA_type":"green","oa_version":"None","author":[{"full_name":"Das, Srijan B","first_name":"Srijan B","last_name":"Das"},{"last_name":"Einramhof","full_name":"Einramhof, Lukas","first_name":"Lukas"},{"last_name":"Bugnet","first_name":"Lisa","full_name":"Bugnet, Lisa"}],"abstract":[{"text":"MESA inlist file for the paper \"Unveiling complex magnetic field configurations in red giant stars\" (10.1051/0004-6361/202450918)","lang":"eng"}],"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"18528"}]},"department":[{"_id":"LiBu"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","citation":{"ama":"Das SB, Einramhof L, Bugnet L. MESA inlist file. 2024. doi:<a href=\"https://doi.org/10.5281/zenodo.12804810\">10.5281/zenodo.12804810</a>","short":"S.B. Das, L. Einramhof, L. Bugnet, (2024).","chicago":"Das, Srijan B, Lukas Einramhof, and Lisa Bugnet. “MESA Inlist File.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.5281/zenodo.12804810\">https://doi.org/10.5281/zenodo.12804810</a>.","ieee":"S. B. Das, L. Einramhof, and L. Bugnet, “MESA inlist file.” Institute of Science and Technology Austria, 2024.","ista":"Das SB, Einramhof L, Bugnet L. 2024. MESA inlist file, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.5281/zenodo.12804810\">10.5281/zenodo.12804810</a>.","mla":"Das, Srijan B., et al. <i>MESA Inlist File</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.5281/zenodo.12804810\">10.5281/zenodo.12804810</a>.","apa":"Das, S. B., Einramhof, L., &#38; Bugnet, L. (2024). MESA inlist file. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.5281/zenodo.12804810\">https://doi.org/10.5281/zenodo.12804810</a>"}},{"publication":"Nature Communications","intvolume":"        15","citation":{"apa":"Dos Santos, C., Cambraia, A., Shrestha, S., Cutler, M., Cottam, M., Perkins, G., … Arrojo E Drigo, R. (2024). Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-53127-2\">https://doi.org/10.1038/s41467-024-53127-2</a>","mla":"Dos Santos, Cristiane, et al. “Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity in Mice.” <i>Nature Communications</i>, vol. 15, 9063, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-53127-2\">10.1038/s41467-024-53127-2</a>.","ama":"Dos Santos C, Cambraia A, Shrestha S, et al. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-53127-2\">10.1038/s41467-024-53127-2</a>","short":"C. Dos Santos, A. Cambraia, S. Shrestha, M. Cutler, M. Cottam, G. Perkins, V. Lev-Ram, B. Roy, C. Acree, K.Y. Kim, T. Deerinck, D. Dean, J.P. Cartailler, P.E. Macdonald, M. Hetzer, M. Ellisman, R. Arrojo E Drigo, Nature Communications 15 (2024).","chicago":"Dos Santos, Cristiane, Amanda Cambraia, Shristi Shrestha, Melanie Cutler, Matthew Cottam, Guy Perkins, Varda Lev-Ram, et al. “Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity in Mice.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-53127-2\">https://doi.org/10.1038/s41467-024-53127-2</a>.","ista":"Dos Santos C, Cambraia A, Shrestha S, Cutler M, Cottam M, Perkins G, Lev-Ram V, Roy B, Acree C, Kim KY, Deerinck T, Dean D, Cartailler JP, Macdonald PE, Hetzer M, Ellisman M, Arrojo E Drigo R. 2024. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. Nature Communications. 15, 9063.","ieee":"C. Dos Santos <i>et al.</i>, “Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024."},"language":[{"iso":"eng"}],"related_material":{"record":[{"id":"22865","status":"public","relation":"research_data"}]},"isi":1,"DOAJ_listed":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file_date_updated":"2024-11-04T10:37:56Z","article_number":"9063","external_id":{"isi":["001426270600023"],"pmid":["39433757"]},"author":[{"full_name":"Dos Santos, Cristiane","first_name":"Cristiane","last_name":"Dos Santos"},{"last_name":"Cambraia","first_name":"Amanda","full_name":"Cambraia, Amanda"},{"first_name":"Shristi","full_name":"Shrestha, Shristi","last_name":"Shrestha"},{"first_name":"Melanie","full_name":"Cutler, Melanie","last_name":"Cutler"},{"full_name":"Cottam, Matthew","first_name":"Matthew","last_name":"Cottam"},{"full_name":"Perkins, Guy","first_name":"Guy","last_name":"Perkins"},{"last_name":"Lev-Ram","full_name":"Lev-Ram, Varda","first_name":"Varda"},{"first_name":"Birbickram","full_name":"Roy, Birbickram","last_name":"Roy"},{"last_name":"Acree","first_name":"Christopher","full_name":"Acree, Christopher"},{"last_name":"Kim","full_name":"Kim, Keun Young","first_name":"Keun Young"},{"full_name":"Deerinck, Thomas","first_name":"Thomas","last_name":"Deerinck"},{"last_name":"Dean","first_name":"Danielle","full_name":"Dean, Danielle"},{"last_name":"Cartailler","full_name":"Cartailler, Jean Philippe","first_name":"Jean Philippe"},{"last_name":"Macdonald","first_name":"Patrick E.","full_name":"Macdonald, Patrick E."},{"last_name":"Hetzer","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","full_name":"Hetzer, Martin W","first_name":"Martin W"},{"last_name":"Ellisman","first_name":"Mark","full_name":"Ellisman, Mark"},{"last_name":"Arrojo E Drigo","full_name":"Arrojo E Drigo, Rafael","first_name":"Rafael"}],"abstract":[{"text":"Caloric restriction (CR) can extend the organism life- and health-span by improving glucose homeostasis. How CR affects the structure-function of pancreatic beta cells remains unknown. We used single nucleus transcriptomics to show that CR increases the expression of genes for beta cell identity, protein processing, and organelle homeostasis. Gene regulatory network analysis reveal that CR activates transcription factors important for beta cell identity and homeostasis, while imaging metabolomics demonstrates that beta cells upon CR are more energetically competent. In fact, high-resolution microscopy show that CR reduces beta cell mitophagy to increase mitochondria mass and the potential for ATP generation. However, CR beta cells have impaired adaptive proliferation in response to high fat diet feeding. Finally, we show that long-term CR delays the onset of beta cell aging hallmarks and promotes cell longevity by reducing beta cell turnover. Therefore, CR could be a feasible approach to preserve compromised beta cell structure-function during aging and diabetes.","lang":"eng"}],"publication_status":"published","date_created":"2024-10-27T23:01:44Z","article_processing_charge":"Yes","doi":"10.1038/s41467-024-53127-2","publication_identifier":{"eissn":["2041-1723"]},"oa_version":"Published Version","publisher":"Springer Nature","_id":"18480","supplementarymaterial":"yes","title":"Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice","article_type":"original","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"oa":1,"OA_place":"publisher","date_published":"2024-10-21T00:00:00Z","das_tickbox":"1","volume":15,"month":"10","dataavailabilitystatement":"Tabular and processed sequencing data is deposited in Zenodo (https://doi.org/10.5281/zenodo.6491943). The single nucleus multiome sequencing data has been deposited in the GEO repository (GSE276572, https://www.ncbi.xyz/geo/query/acc.cgi?acc=GSE276572). Source data are provided with this paper.","department":[{"_id":"MaHe"}],"year":"2024","file":[{"file_name":"2024_NatureComm_dosSantos.pdf","relation":"main_file","content_type":"application/pdf","creator":"dernst","date_updated":"2024-11-04T10:37:56Z","file_size":7358742,"checksum":"b936b1c047f41cd427f00e3dc79327d3","date_created":"2024-11-04T10:37:56Z","file_id":"18502","access_level":"open_access","success":1}],"acknowledgement":"We are thankful to Michelle Reyzer from the Vanderbilt Mass Spectrometry Research Center for assistance with MALDI-MS imaging and analysis, to the outstanding team at the Vanderbilt Mouse Metabolic Phenotyping Center for all the assistance with in vivo glucose homeostasis tests (DK135073, 1S10RR028101-01). We also thank the University of Michigan Animal Phenotyping Core for conducting the bomb calorimetry experiments (1U2CDK110768, DK020575, and DK089503). This research was supported by recruitment funds from the Vanderbilt’s Department of Molecular Physiology and Biophysics and NIH grants 1R03DK127484, 5U24DK097771, and 1R01DK138141 to RAeD, by a grant from the Canadian Institutes of Health Research (CIHR; 487188) to PEM, by and NIH DK132669 to D.D. PEM holds the Canada Research Chair in Islet Biology.","quality_controlled":"1","researchdata_availability":"yes","OA_type":"gold","date_updated":"2026-10-16T09:00:16Z","day":"21","pmid":1,"fulldoi":"https://doi.org/10.1038/s41467-024-53127-2","ddc":["570"],"scopus_import":"1","status":"public","has_accepted_license":"1","type":"journal_article"},{"month":"04","volume":384,"oa":1,"date_published":"2024-04-04T00:00:00Z","das_tickbox":"1","OA_place":"repository","_id":"15316","supplementarymaterial":"yes","publisher":"AAAS","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615865"}],"article_type":"original","title":"Lifelong persistence of nuclear RNAs in the mouse brain","external_id":{"pmid":["38574132"],"isi":["001253335100031"]},"author":[{"first_name":"Sara","full_name":"Zocher, Sara","last_name":"Zocher"},{"first_name":"Asako","full_name":"Mccloskey, Asako","last_name":"Mccloskey"},{"first_name":"Anne","full_name":"Karasinsky, Anne","last_name":"Karasinsky"},{"last_name":"Schulte","full_name":"Schulte, Roberta","first_name":"Roberta"},{"last_name":"Friedrich","first_name":"Ulrike","full_name":"Friedrich, Ulrike"},{"last_name":"Lesche","first_name":"Mathias","full_name":"Lesche, Mathias"},{"last_name":"Rund","first_name":"Nicole","full_name":"Rund, Nicole"},{"last_name":"Gage","first_name":"Fred H.","full_name":"Gage, Fred H."},{"last_name":"Hetzer","first_name":"Martin W","full_name":"Hetzer, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X"},{"full_name":"Toda, Tomohisa","first_name":"Tomohisa","last_name":"Toda"}],"abstract":[{"text":"Genomic DNA that resides in the nuclei of mammalian neurons can be as old as the organism itself. The life span of nuclear RNAs, which are critical for proper chromatin architecture and transcription regulation, has not been determined in adult tissues. In this work, we identified and characterized nuclear RNAs that do not turn over for at least 2 years in a subset of postnatally born cells in the mouse brain. These long-lived RNAs were stably retained in nuclei in a neural cell type–specific manner and were required for the maintenance of heterochromatin. Thus, the life span of neural cells may depend on both the molecular longevity of DNA for the storage of genetic information and also the extreme stability of RNA for the functional organization of chromatin.","lang":"eng"}],"publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"oa_version":"Submitted Version","article_processing_charge":"No","publication_status":"published","doi":"10.1126/science.adf3481","date_created":"2024-04-14T22:01:01Z","publication":"Science","intvolume":"       384","citation":{"apa":"Zocher, S., Mccloskey, A., Karasinsky, A., Schulte, R., Friedrich, U., Lesche, M., … Toda, T. (2024). Lifelong persistence of nuclear RNAs in the mouse brain. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.adf3481\">https://doi.org/10.1126/science.adf3481</a>","mla":"Zocher, Sara, et al. “Lifelong Persistence of Nuclear RNAs in the Mouse Brain.” <i>Science</i>, vol. 384, no. 6691, AAAS, 2024, pp. 53–59, doi:<a href=\"https://doi.org/10.1126/science.adf3481\">10.1126/science.adf3481</a>.","short":"S. Zocher, A. Mccloskey, A. Karasinsky, R. Schulte, U. Friedrich, M. Lesche, N. Rund, F.H. Gage, M. Hetzer, T. Toda, Science 384 (2024) 53–59.","ama":"Zocher S, Mccloskey A, Karasinsky A, et al. Lifelong persistence of nuclear RNAs in the mouse brain. <i>Science</i>. 2024;384(6691):53-59. doi:<a href=\"https://doi.org/10.1126/science.adf3481\">10.1126/science.adf3481</a>","chicago":"Zocher, Sara, Asako Mccloskey, Anne Karasinsky, Roberta Schulte, Ulrike Friedrich, Mathias Lesche, Nicole Rund, Fred H. Gage, Martin Hetzer, and Tomohisa Toda. “Lifelong Persistence of Nuclear RNAs in the Mouse Brain.” <i>Science</i>. AAAS, 2024. <a href=\"https://doi.org/10.1126/science.adf3481\">https://doi.org/10.1126/science.adf3481</a>.","ieee":"S. Zocher <i>et al.</i>, “Lifelong persistence of nuclear RNAs in the mouse brain,” <i>Science</i>, vol. 384, no. 6691. AAAS, pp. 53–59, 2024.","ista":"Zocher S, Mccloskey A, Karasinsky A, Schulte R, Friedrich U, Lesche M, Rund N, Gage FH, Hetzer M, Toda T. 2024. Lifelong persistence of nuclear RNAs in the mouse brain. Science. 384(6691), 53–59."},"isi":1,"corr_author":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","language":[{"iso":"eng"}],"related_material":{"link":[{"relation":"press_release","url":"https://ista.ac.at/en/news/nerve-cells-old-at-heart/","description":"News on ISTA website"}]},"type":"journal_article","status":"public","page":"53-59","issue":"6691","date_updated":"2026-10-16T08:59:32Z","day":"04","pmid":1,"fulldoi":"https://doi.org/10.1126/science.adf3481","scopus_import":"1","acknowledgement":"European Research Council: ERC-2018-STG, 804468 EAGER; European Research Council: ERC-2023-COG, 101125034 NEUTIME; Deutsche Forschungsgemeinschaft: TO1347/4-1; Boehringer Ingelheim Stiftung; Deutsches Zentrum für Neurodegenerative Erkrankungen","quality_controlled":"1","OA_type":"green","researchdata_availability":"yes","year":"2024","dataavailabilitystatement":"All data are available in the main text, figures, or supplementary materials. EU-RNA-seq data were submitted to the Gene Expression Omnibus (GEO) under accession no. GSE248101.","department":[{"_id":"MaHe"}]},{"month":"10","OA_place":"repository","date_published":"2024-10-10T00:00:00Z","oa":1,"type":"research_data_reference","status":"public","main_file_link":[{"url":"https://doi.org/10.5061/dryad.mpg4f4r89","open_access":"1"}],"title":"Multivariate analysis of Pleurodeles waltl injection outcomes using FAMD FactoMineR (RStudio 4.3.2) used to probe sources of variability during an Adeno-associated viral (AAV) screen","ddc":["570"],"fulldoi":"https://doi.org/10.5061/dryad.mpg4f4r89","date_updated":"2026-10-16T08:58:22Z","_id":"22803","day":"10","publisher":"Repository","oa_version":"None","OA_type":"green","doi":"10.5061/dryad.mpg4f4r89","article_processing_charge":"No","date_created":"2026-09-04T10:10:52Z","author":[{"first_name":"Eliza","full_name":"Jaeger, Eliza","last_name":"Jaeger"}],"abstract":[{"text":"In this study, we analyzed the efficiency of different adeno-associated viral (AAV) injections in transfecting neurons in the salamander Pleurodeles waltl. To query sources of variation in AAV injection outcomes, we analyzed metadata and outcomes for an additional 68 intraparenchymal injections performed 39 in post-metamorphic Pleurodeles salamanders. This dataset included both quantitative variables (age, weight, viral genomes (v.g.) injected, and a cell transduction score ranging from 0 to 4, see STAR Methods) and categorical variables (here referred to as qualitative variables: serotype, promoter, reporter, single vs. dual injection, manufacturer, and injection site). To assess the associations between these variables, we performed a Factor Analysis for Mixed Data (FAMD), a principal component method that is designed to determine significant sources of variability within datasets that contain both quantitative and qualitative data types. This dataset contains the injection outcomes and metadata for AAV injections administered in the salamander Pleurodeles waltl. The RactoMineR package (https://CRAN.R-project.org/package=FactoMineR) was used to determine significant contributions of a number of variables contributing to injection outcomes. Analysis of these data revealed that, among other factors, age co-varies with injection score. Therefore, we conclude that increased animal age decreases the efficacy of this tool.","lang":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","department":[{"_id":"E-Lib"}],"related_material":{"record":[{"status":"public","id":"15016","relation":"used_in_publication"}]},"citation":{"mla":"Jaeger, Eliza. <i>Multivariate Analysis of Pleurodeles Waltl Injection Outcomes Using FAMD FactoMineR (RStudio 4.3.2) Used to Probe Sources of Variability during an Adeno-Associated Viral (AAV) Screen</i>. Repository, 2024, doi:<a href=\"https://doi.org/10.5061/dryad.mpg4f4r89\">10.5061/dryad.mpg4f4r89</a>.","apa":"Jaeger, E. (2024). Multivariate analysis of Pleurodeles waltl injection outcomes using FAMD FactoMineR (RStudio 4.3.2) used to probe sources of variability during an Adeno-associated viral (AAV) screen. Repository. <a href=\"https://doi.org/10.5061/dryad.mpg4f4r89\">https://doi.org/10.5061/dryad.mpg4f4r89</a>","ama":"Jaeger E. Multivariate analysis of Pleurodeles waltl injection outcomes using FAMD FactoMineR (RStudio 4.3.2) used to probe sources of variability during an Adeno-associated viral (AAV) screen. 2024. doi:<a href=\"https://doi.org/10.5061/dryad.mpg4f4r89\">10.5061/dryad.mpg4f4r89</a>","short":"E. Jaeger, (2024).","chicago":"Jaeger, Eliza. “Multivariate Analysis of Pleurodeles Waltl Injection Outcomes Using FAMD FactoMineR (RStudio 4.3.2) Used to Probe Sources of Variability during an Adeno-Associated Viral (AAV) Screen.” Repository, 2024. <a href=\"https://doi.org/10.5061/dryad.mpg4f4r89\">https://doi.org/10.5061/dryad.mpg4f4r89</a>.","ieee":"E. Jaeger, “Multivariate analysis of Pleurodeles waltl injection outcomes using FAMD FactoMineR (RStudio 4.3.2) used to probe sources of variability during an Adeno-associated viral (AAV) screen.” Repository, 2024.","ista":"Jaeger E. 2024. Multivariate analysis of Pleurodeles waltl injection outcomes using FAMD FactoMineR (RStudio 4.3.2) used to probe sources of variability during an Adeno-associated viral (AAV) screen, Repository, <a href=\"https://doi.org/10.5061/dryad.mpg4f4r89\">10.5061/dryad.mpg4f4r89</a>."}},{"OA_place":"repository","date_published":"2024-10-21T00:00:00Z","oa":1,"month":"10","status":"public","type":"research_data_reference","title":"Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity","ddc":["570"],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/zenodo.6491943"}],"publisher":"Repository","fulldoi":"https://doi.org/10.5281/zenodo.6491943","date_updated":"2026-10-16T09:00:15Z","_id":"22865","day":"21","doi":"10.5281/zenodo.6491943","date_created":"2026-09-09T08:43:34Z","article_processing_charge":"No","oa_version":"None","OA_type":"green","abstract":[{"text":"Dataset for Dos Santos et al, 2024","lang":"eng"}],"author":[{"last_name":"Arrojo e Drigo","first_name":"Rafael","full_name":"Arrojo e Drigo, Rafael"}],"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"18480"}]},"department":[{"_id":"MaHe"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","citation":{"ama":"Arrojo e Drigo R. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity. 2024. doi:<a href=\"https://doi.org/10.5281/zenodo.6491943\">10.5281/zenodo.6491943</a>","short":"R. Arrojo e Drigo, (2024).","ista":"Arrojo e Drigo R. 2024. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity, Repository, <a href=\"https://doi.org/10.5281/zenodo.6491943\">10.5281/zenodo.6491943</a>.","ieee":"R. Arrojo e Drigo, “Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity.” Repository, 2024.","chicago":"Arrojo e Drigo, Rafael. “Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity.” Repository, 2024. <a href=\"https://doi.org/10.5281/zenodo.6491943\">https://doi.org/10.5281/zenodo.6491943</a>.","mla":"Arrojo e Drigo, Rafael. <i>Calorie Restriction Increases Insulin Sensitivity to Promote Beta Cell Homeostasis and Longevity</i>. Repository, 2024, doi:<a href=\"https://doi.org/10.5281/zenodo.6491943\">10.5281/zenodo.6491943</a>.","apa":"Arrojo e Drigo, R. (2024). Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity. Repository. <a href=\"https://doi.org/10.5281/zenodo.6491943\">https://doi.org/10.5281/zenodo.6491943</a>"}},{"oa_version":"None","OA_type":"green","date_created":"2026-10-16T09:10:47Z","doi":"10.5281/zenodo.13889273","article_processing_charge":"No","author":[{"last_name":"Tang","first_name":"Xuechen","full_name":"Tang, Xuechen"}],"abstract":[{"lang":"eng","text":"The attached trajectories illustrate the thinning of the membrane by DSC2, the impact of Y53A, R54A mutations on this process.In order to comply with the size limit, the initial conformations as well as one illustrative example of the final productive simulation of each simulated system are provided herewith. The initial conformations are provided in PDB format, while the final productive simulations are uploaded in NetCDF (AMBER) format. "}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"18522"}]},"citation":{"ieee":"X. Tang, “The interaction between the DSC2 and the cell membrane.” Zenodo, 2024.","ista":"Tang X. 2024. The interaction between the DSC2 and the cell membrane, Zenodo, <a href=\"https://doi.org/10.5281/zenodo.13889273\">10.5281/zenodo.13889273</a>.","chicago":"Tang, Xuechen. “The Interaction between the DSC2 and the Cell Membrane.” Zenodo, 2024. <a href=\"https://doi.org/10.5281/zenodo.13889273\">https://doi.org/10.5281/zenodo.13889273</a>.","short":"X. Tang, (2024).","ama":"Tang X. The interaction between the DSC2 and the cell membrane. 2024. doi:<a href=\"https://doi.org/10.5281/zenodo.13889273\">10.5281/zenodo.13889273</a>","apa":"Tang, X. (2024). The interaction between the DSC2 and the cell membrane. Zenodo. <a href=\"https://doi.org/10.5281/zenodo.13889273\">https://doi.org/10.5281/zenodo.13889273</a>","mla":"Tang, Xuechen. <i>The Interaction between the DSC2 and the Cell Membrane</i>. Zenodo, 2024, doi:<a href=\"https://doi.org/10.5281/zenodo.13889273\">10.5281/zenodo.13889273</a>."},"month":"10","OA_place":"repository","date_published":"2024-10-04T00:00:00Z","oa":1,"type":"research_data_reference","status":"public","main_file_link":[{"url":"https://doi.org/10.5281/zenodo.13889273","open_access":"1"}],"title":"The interaction between the DSC2 and the cell membrane","ddc":["570"],"fulldoi":"https://doi.org/10.5281/zenodo.13889273","_id":"23143","date_updated":"2026-10-16T09:14:37Z","day":"04","publisher":"Zenodo"},{"ddc":["540"],"scopus_import":"1","pmid":1,"fulldoi":"https://doi.org/10.1021/acsaelm.3c00055","day":"28","date_updated":"2026-10-16T09:18:36Z","issue":"5","page":"2807-215","project":[{"grant_number":"M02889","name":"Bottom-up Engineering for Thermoelectric Applications","_id":"9B8804FC-BA93-11EA-9121-9846C619BF3A"},{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"has_accepted_license":"1","status":"public","type":"journal_article","department":[{"_id":"MaIb"}],"file":[{"date_updated":"2024-07-16T07:54:21Z","content_type":"application/pdf","relation":"main_file","file_name":"2024_ACSAppElecMaterials_Nan.pdf","creator":"dernst","success":1,"file_size":5851865,"date_created":"2024-07-16T07:54:21Z","file_id":"17250","access_level":"open_access","checksum":"1f743eaf4fc988cd30102b7c2f12c15d"}],"year":"2024","researchdata_availability":"no","quality_controlled":"1","acknowledgement":"Open Access is funded by the Austrian Science Fund (FWF). B.N., M.L., Y.Z., K.X., and X.H. thank the China Scholarship Council (CSC) for the scholarship support. C.C. received funding from the FWF “Lise Meitner Fellowship” grant agreement M 2889-N. M.I. acknowledges the financial support from ISTA and the Werner Siemens Foundation. ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457 and project NANOGEN (PID2020-116093RB-C43) funded by MCIN/AEI/10.13039/501100011033/. ICN2 was supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and was funded by the CERCA Programme/Generalitat de Catalunya. J.L. is a Serra Húnter Fellow and is grateful to the ICREA Academia program and projects MICINN/FEDER PID2021-124572OB-C31 and 2021 SGR 01061. K.H.L. acknowledges support from the National Natural Science Foundation of China (22208293). This study is part of the Advanced Materials programme and was supported by MCIN with funding from European Union NextGenerationEU (PRTR-C17.I1) and by Generalitat de Catalunya.","title":"Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature","article_type":"review","publisher":"American Chemical Society","_id":"13093","supplementarymaterial":"yes","date_published":"2024-05-28T00:00:00Z","das_tickbox":"0","oa":1,"month":"05","volume":6,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"citation":{"ama":"Nan B, Li M, Zhang Y, et al. Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. <i>ACS Applied Electronic Materials</i>. 2024;6(5):2807-215. doi:<a href=\"https://doi.org/10.1021/acsaelm.3c00055\">10.1021/acsaelm.3c00055</a>","short":"B. Nan, M. Li, Y. Zhang, K. Xiao, K.H. Lim, C. Chang, X. Han, Y. Zuo, J. Li, J. Arbiol, J. Llorca, M. Ibáñez, A. Cabot, ACS Applied Electronic Materials 6 (2024) 2807–215.","chicago":"Nan, Bingfei, Mengyao Li, Yu Zhang, Ke Xiao, Khak Ho Lim, Cheng Chang, Xu Han, et al. “Engineering of Thermoelectric Composites Based on Silver Selenide in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic Materials</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/acsaelm.3c00055\">https://doi.org/10.1021/acsaelm.3c00055</a>.","ieee":"B. Nan <i>et al.</i>, “Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature,” <i>ACS Applied Electronic Materials</i>, vol. 6, no. 5. American Chemical Society, pp. 2807–215, 2024.","ista":"Nan B, Li M, Zhang Y, Xiao K, Lim KH, Chang C, Han X, Zuo Y, Li J, Arbiol J, Llorca J, Ibáñez M, Cabot A. 2024. Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. ACS Applied Electronic Materials. 6(5), 2807–215.","mla":"Nan, Bingfei, et al. “Engineering of Thermoelectric Composites Based on Silver Selenide in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic Materials</i>, vol. 6, no. 5, American Chemical Society, 2024, pp. 2807–215, doi:<a href=\"https://doi.org/10.1021/acsaelm.3c00055\">10.1021/acsaelm.3c00055</a>.","apa":"Nan, B., Li, M., Zhang, Y., Xiao, K., Lim, K. H., Chang, C., … Cabot, A. (2024). Engineering of thermoelectric composites based on silver selenide in aqueous solution and ambient temperature. <i>ACS Applied Electronic Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaelm.3c00055\">https://doi.org/10.1021/acsaelm.3c00055</a>"},"intvolume":"         6","publication":"ACS Applied Electronic Materials","publication_status":"published","article_processing_charge":"Yes (in subscription journal)","doi":"10.1021/acsaelm.3c00055","date_created":"2023-05-28T22:01:03Z","publication_identifier":{"eissn":["2637-6113"]},"oa_version":"Published Version","file_date_updated":"2024-07-16T07:54:21Z","author":[{"first_name":"Bingfei","full_name":"Nan, Bingfei","last_name":"Nan"},{"full_name":"Li, Mengyao","first_name":"Mengyao","last_name":"Li"},{"last_name":"Zhang","full_name":"Zhang, Yu","first_name":"Yu"},{"last_name":"Xiao","full_name":"Xiao, Ke","first_name":"Ke"},{"first_name":"Khak Ho","full_name":"Lim, Khak Ho","last_name":"Lim"},{"last_name":"Chang","first_name":"Cheng","full_name":"Chang, Cheng","orcid":"0000-0002-9515-4277","id":"9E331C2E-9F27-11E9-AE48-5033E6697425"},{"full_name":"Han, Xu","first_name":"Xu","last_name":"Han"},{"last_name":"Zuo","full_name":"Zuo, Yong","first_name":"Yong"},{"first_name":"Junshan","full_name":"Li, Junshan","last_name":"Li"},{"last_name":"Arbiol","first_name":"Jordi","full_name":"Arbiol, Jordi"},{"full_name":"Llorca, Jordi","first_name":"Jordi","last_name":"Llorca"},{"last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","first_name":"Maria","full_name":"Ibáñez, Maria"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"abstract":[{"text":"The direct, solid state, and reversible conversion between heat and electricity using thermoelectric devices finds numerous potential uses, especially around room temperature. However, the relatively high material processing cost limits their real applications. Silver selenide (Ag2Se) is one of the very few n-type thermoelectric (TE) materials for room-temperature applications. Herein, we report a room temperature, fast, and aqueous-phase synthesis approach to produce Ag2Se, which can be extended to other metal chalcogenides. These materials reach TE figures of merit (zT) of up to 0.76 at 380 K. To improve these values, bismuth sulfide (Bi2S3) particles also prepared in an aqueous solution are incorporated into the Ag2Se matrix. In this way, a series of Ag2Se/Bi2S3 composites with Bi2S3 wt % of 0.5, 1.0, and 1.5 are prepared by solution blending and hot-press sintering. The presence of Bi2S3 significantly improves the Seebeck coefficient and power factor while at the same time decreasing the thermal conductivity with no apparent drop in electrical conductivity. Thus, a maximum zT value of 0.96 is achieved in the composites with 1.0 wt % Bi2S3 at 370 K. Furthermore, a high average zT value (zTave) of 0.93 in the 300–390 K range is demonstrated.","lang":"eng"}],"external_id":{"isi":["000986859000001"],"pmid":["38828037"]}},{"acknowledgement":"The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF) and the Lab Support Facility (LSF). This work was financially supported by the Institute of Science and Technology Austria and the Werner Siemens Foundation.","quality_controlled":"1","OA_type":"hybrid","researchdata_availability":"no","year":"2024","file":[{"success":1,"file_size":1371995,"access_level":"open_access","date_created":"2025-02-17T15:08:55Z","file_id":"19047","checksum":"ddb41f1ce2333484ab5cd109ac2941c0","date_updated":"2025-02-17T15:08:55Z","content_type":"application/pdf","relation":"main_file","file_name":"2024_JoVE_Fiedler.pdf","creator":"dernst"}],"department":[{"_id":"MaIb"}],"type":"journal_article","license":"https://creativecommons.org/licenses/by-nc-nd/3.0/","status":"public","has_accepted_license":"1","APC_amount":"4394,84 EUR","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"issue":"207","day":"01","date_updated":"2026-10-16T09:18:16Z","pmid":1,"fulldoi":"https://doi.org/10.3791/66278","scopus_import":"1","ddc":["530"],"external_id":{"pmid":["38829127"],"isi":["001281657200005"]},"abstract":[{"lang":"eng","text":"In recent years, solution processes have gained considerable traction as a cost-effective and scalable method to produce high-performance thermoelectric materials. The process entails a series of critical steps: synthesis, purification, thermal treatments, and consolidation, each playing a pivotal role in determining performance, stability, and reproducibility. We have noticed a need for more comprehensive details for each of the described steps in most published works. Recognizing the significance of detailed synthetic protocols, we describe here the approach used to synthesize and characterize one of the highest-performing polycrystalline p-type SnSe. In particular, we report the synthesis of SnSe particles in water and the subsequent surface treatment with CdSe molecular complexes that yields CdSe-SnSe nanocomposites upon consolidation. Moreover, the surface treatment inhibits grain growth through Zenner pinning of secondary phase CdSe nanoparticles and enhances defect formation at different length scales. The enhanced complexity in the CdSe-SnSe nanocomposite microstructure with respect to SnSe promotes phonon scattering and thereby significantly reduces the thermal conductivity. Such surface engineering provides opportunities in solution processing for introducing and controlling defects, making it possible to optimize the transport properties and attain a high thermoelectric figure of merit."}],"author":[{"first_name":"Christine","full_name":"Fiedler, Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","last_name":"Fiedler"},{"full_name":"Liu, Yu","first_name":"Yu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","last_name":"Liu"},{"last_name":"Ibáñez","full_name":"Ibáñez, Maria","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843"}],"file_date_updated":"2025-02-17T15:08:55Z","article_number":"e66278","oa_version":"Published Version","publication_identifier":{"issn":["1940-087X"]},"publication_status":"published","article_processing_charge":"Yes (in subscription journal)","date_created":"2024-06-09T22:01:02Z","doi":"10.3791/66278","publication":"Journal of Visualized Experiments","intvolume":"      2024","citation":{"chicago":"Fiedler, Christine, Yu Liu, and Maria Ibáñez. “Solution-Processed, Surface-Engineered, Polycrystalline CdSe-SnSe Exhibiting Low Thermal Conductivity.” <i>Journal of Visualized Experiments</i>. MyJove Corporation, 2024. <a href=\"https://doi.org/10.3791/66278\">https://doi.org/10.3791/66278</a>.","ista":"Fiedler C, Liu Y, Ibáñez M. 2024. Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. Journal of Visualized Experiments. 2024(207), e66278.","ieee":"C. Fiedler, Y. Liu, and M. Ibáñez, “Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity,” <i>Journal of Visualized Experiments</i>, vol. 2024, no. 207. MyJove Corporation, 2024.","short":"C. Fiedler, Y. Liu, M. Ibáñez, Journal of Visualized Experiments 2024 (2024).","ama":"Fiedler C, Liu Y, Ibáñez M. Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. <i>Journal of Visualized Experiments</i>. 2024;2024(207). doi:<a href=\"https://doi.org/10.3791/66278\">10.3791/66278</a>","apa":"Fiedler, C., Liu, Y., &#38; Ibáñez, M. (2024). Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. <i>Journal of Visualized Experiments</i>. MyJove Corporation. <a href=\"https://doi.org/10.3791/66278\">https://doi.org/10.3791/66278</a>","mla":"Fiedler, Christine, et al. “Solution-Processed, Surface-Engineered, Polycrystalline CdSe-SnSe Exhibiting Low Thermal Conductivity.” <i>Journal of Visualized Experiments</i>, vol. 2024, no. 207, e66278, MyJove Corporation, 2024, doi:<a href=\"https://doi.org/10.3791/66278\">10.3791/66278</a>."},"isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","corr_author":"1","language":[{"iso":"eng"}],"related_material":{"record":[{"relation":"dissertation_contains","id":"22626","status":"public"}]},"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","short":"CC BY-NC-ND (3.0)","image":"/images/cc_by_nc_nd.png"},"volume":2024,"month":"05","oa":1,"das_tickbox":"0","OA_place":"publisher","date_published":"2024-05-01T00:00:00Z","supplementarymaterial":"no","_id":"17124","publisher":"MyJove Corporation","article_type":"original","title":"Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity"},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"oa":1,"OA_place":"publisher","date_published":"2024-12-01T00:00:00Z","das_tickbox":"1","volume":15,"month":"12","publisher":"Springer Nature","supplementarymaterial":"yes","_id":"18522","title":"The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi","article_type":"original","file_date_updated":"2025-01-22T14:36:33Z","article_number":"9257","external_id":{"pmid":["39461958"],"isi":["001345548100007"]},"abstract":[{"text":"The Golgi apparatus is essential for protein sorting, yet its quality control mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic length of α-helical transmembrane domains (TMDs) at the Golgi. Thereby the Dsc complex likely interacts with orphaned ER and Golgi proteins that have shorter TMDs and ubiquitinates them for targeted degradation. Some Dsc substrates will be extracted by Cdc48 for endosome and Golgi associated proteasomal degradation (EGAD), while others will undergo ESCRT dependent vacuolar degradation. Some substrates are degraded by both, EGAD- or ESCRT pathways. The accumulation of Dsc substrates entails a specific increase in glycerophospholipids with shorter and asymmetric fatty acyl chains. Hence, the Dsc complex mediates the selective degradation of orphaned proteins at the sorting center of cells, which prevents their spreading across other organelles and thereby preserves cellular membrane protein and lipid composition.","lang":"eng"}],"author":[{"first_name":"Yannick","full_name":"Weyer, Yannick","last_name":"Weyer"},{"last_name":"Schwabl","first_name":"Sinead I.","full_name":"Schwabl, Sinead I."},{"full_name":"Tang, Xuechen","first_name":"Xuechen","last_name":"Tang"},{"first_name":"Astha","full_name":"Purwar, Astha","last_name":"Purwar"},{"last_name":"Siegmann","first_name":"Konstantin","full_name":"Siegmann, Konstantin"},{"first_name":"Angela","full_name":"Ruepp, Angela","last_name":"Ruepp"},{"first_name":"Theresia","full_name":"Dunzendorfer-Matt, Theresia","last_name":"Dunzendorfer-Matt"},{"first_name":"Michael A.","full_name":"Widerin, Michael A.","last_name":"Widerin"},{"last_name":"Niedrist","full_name":"Niedrist, Veronika","first_name":"Veronika"},{"last_name":"Mutsters","first_name":"Noa J.M.","full_name":"Mutsters, Noa J.M."},{"first_name":"Maria G.","full_name":"Tettamanti, Maria G.","last_name":"Tettamanti"},{"id":"caffa136-9669-11ed-9092-ceac12ac9c05","first_name":"Sabine","full_name":"Weys, Sabine","last_name":"Weys"},{"last_name":"Sarg","full_name":"Sarg, Bettina","first_name":"Bettina"},{"full_name":"Kremser, Leopold","first_name":"Leopold","last_name":"Kremser"},{"last_name":"Liedl","full_name":"Liedl, Klaus R.","first_name":"Klaus R."},{"last_name":"Schmidt","full_name":"Schmidt, Oliver","first_name":"Oliver"},{"full_name":"Teis, David","first_name":"David","last_name":"Teis"}],"date_created":"2024-11-10T23:01:58Z","doi":"10.1038/s41467-024-53676-6","article_processing_charge":"Yes","publication_status":"published","publication_identifier":{"eissn":["2041-1723"]},"oa_version":"Published Version","publication":"Nature Communications","intvolume":"        15","citation":{"apa":"Weyer, Y., Schwabl, S. I., Tang, X., Purwar, A., Siegmann, K., Ruepp, A., … Teis, D. (2024). The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-53676-6\">https://doi.org/10.1038/s41467-024-53676-6</a>","mla":"Weyer, Yannick, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” <i>Nature Communications</i>, vol. 15, 9257, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-53676-6\">10.1038/s41467-024-53676-6</a>.","short":"Y. Weyer, S.I. Schwabl, X. Tang, A. Purwar, K. Siegmann, A. Ruepp, T. Dunzendorfer-Matt, M.A. Widerin, V. Niedrist, N.J.M. Mutsters, M.G. Tettamanti, S. Weys, B. Sarg, L. Kremser, K.R. Liedl, O. Schmidt, D. Teis, Nature Communications 15 (2024).","ama":"Weyer Y, Schwabl SI, Tang X, et al. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-53676-6\">10.1038/s41467-024-53676-6</a>","chicago":"Weyer, Yannick, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-53676-6\">https://doi.org/10.1038/s41467-024-53676-6</a>.","ieee":"Y. Weyer <i>et al.</i>, “The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","ista":"Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser L, Liedl KR, Schmidt O, Teis D. 2024. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications. 15, 9257."},"language":[{"iso":"eng"}],"related_material":{"record":[{"relation":"research_data","status":"public","id":"23143"},{"status":"public","id":"23144","relation":"research_data"}]},"isi":1,"DOAJ_listed":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","has_accepted_license":"1","type":"journal_article","date_updated":"2026-10-16T09:15:18Z","day":"01","pmid":1,"fulldoi":"https://doi.org/10.1038/s41467-024-53676-6","ddc":["570"],"scopus_import":"1","acknowledgement":"We thank Snezhana Oliferenko, Hesso Farhan, Chris Dunworth, and Lukas A Huber for critically reading the manuscript, Ming Li, Peter Espenshade, Sebastien Leon, and Scott Emr for reagents, Bob Kaufmann for help in characterizing the Dsc2 L1 loop mutant. This research was funded in part by the Austrian Science Fund (FWF) (10.55776/P32161, 10.55776/P34907, 10.55776/DOC82 to DT, and 10.55776/P36187 to OS), by a Lipotype lipidomics excellence award (LEA 2019) to OS, by a Luxembourg National Research Fund (FNR): Grant #13571826 to YW, and by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 847681 (to KRL). For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.","quality_controlled":"1","OA_type":"gold","researchdata_availability":"yes","dataavailabilitystatement":"All relevant data has been included in the paper in the main figures and in supplementary data 1–4, supplementary tables 1 and 2, and figures. The proteomics data have been deposited in PRIDE (accession number: PXD055553). The original trajectories for the MD simulations have been deposited in Zenodo and are available under 10.5281/zenodo.13889274 and 10.5281/zenodo.13889576. All other data that support the findings of this study are available from the corresponding author upon request. Source data are provided with this paper.","year":"2024","file":[{"success":1,"access_level":"open_access","date_created":"2025-01-22T14:36:33Z","file_id":"18870","checksum":"32c986fc3babec999c03a5c043310f40","file_size":5634494,"date_updated":"2025-01-22T14:36:33Z","creator":"dernst","content_type":"application/pdf","file_name":"2024_NatureComm_Weyer.pdf","relation":"main_file"}]},{"dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author upon reasonable request.","department":[{"_id":"MaIb"}],"year":"2024","acknowledgement":"G.Z. and Q.S. contributed equally to this work. This work was supported by the National Natural Science Foundation of China (52105329, 52175300) and the Heilongjiang Provincial Natural Science Foundation of China (LH2022E059). G.Z., X.L., and C.Z. thank the China Scholarship Council (CSC) for the scholarship support. This research was supported by the Scientific Service Units of ISTA through resources provided by the Electron Microscopy Facility. S.H. and M.I. acknowledge funding by ISTA and Werner Siemens.","quality_controlled":"1","keyword":["Mechanical Engineering","Mechanics of Materials","General Materials Science"],"researchdata_availability":"upon request","date_updated":"2026-10-16T09:17:57Z","day":"04","fulldoi":"https://doi.org/10.1002/adma.202305128","pmid":1,"scopus_import":"1","status":"public","type":"journal_article","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"issue":"1","publication":"Advanced Materials","intvolume":"        36","citation":{"mla":"Zeng, Guifang, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” <i>Advanced Materials</i>, vol. 36, no. 1, 2305128, Wiley, 2024, doi:<a href=\"https://doi.org/10.1002/adma.202305128\">10.1002/adma.202305128</a>.","apa":"Zeng, G., Sun, Q., Horta, S., Wang, S., Lu, X., Zhang, C., … Cabot, A. (2024). A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. <i>Advanced Materials</i>. Wiley. <a href=\"https://doi.org/10.1002/adma.202305128\">https://doi.org/10.1002/adma.202305128</a>","chicago":"Zeng, Guifang, Qing Sun, Sharona Horta, Shang Wang, Xuan Lu, Chaoyue Zhang, Jing Li, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” <i>Advanced Materials</i>. Wiley, 2024. <a href=\"https://doi.org/10.1002/adma.202305128\">https://doi.org/10.1002/adma.202305128</a>.","ista":"Zeng G, Sun Q, Horta S, Wang S, Lu X, Zhang C, Li J, Li J, Ci L, Tian Y, Ibáñez M, Cabot A. 2024. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 36(1), 2305128.","ieee":"G. Zeng <i>et al.</i>, “A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries,” <i>Advanced Materials</i>, vol. 36, no. 1. Wiley, 2024.","short":"G. Zeng, Q. Sun, S. Horta, S. Wang, X. Lu, C. Zhang, J. Li, J. Li, L. Ci, Y. Tian, M. Ibáñez, A. Cabot, Advanced Materials 36 (2024).","ama":"Zeng G, Sun Q, Horta S, et al. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. <i>Advanced Materials</i>. 2024;36(1). doi:<a href=\"https://doi.org/10.1002/adma.202305128\">10.1002/adma.202305128</a>"},"language":[{"iso":"eng"}],"isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_number":"2305128","external_id":{"isi":["001085681000001"],"pmid":["37555532"]},"author":[{"full_name":"Zeng, Guifang","first_name":"Guifang","last_name":"Zeng"},{"last_name":"Sun","full_name":"Sun, Qing","first_name":"Qing"},{"last_name":"Horta","full_name":"Horta, Sharona","first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc"},{"last_name":"Wang","full_name":"Wang, Shang","first_name":"Shang"},{"full_name":"Lu, Xuan","first_name":"Xuan","last_name":"Lu"},{"full_name":"Zhang, Chaoyue","first_name":"Chaoyue","last_name":"Zhang"},{"last_name":"Li","full_name":"Li, Jing","first_name":"Jing"},{"first_name":"Junshan","full_name":"Li, Junshan","last_name":"Li"},{"first_name":"Lijie","full_name":"Ci, Lijie","last_name":"Ci"},{"last_name":"Tian","first_name":"Yanhong","full_name":"Tian, Yanhong"},{"first_name":"Maria","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","last_name":"Ibáñez"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"}],"abstract":[{"text":"Low‐cost, safe, and environmental‐friendly rechargeable aqueous zinc‐ion batteries (ZIBs) are promising as next‐generation energy storage devices for wearable electronics among other applications. However, sluggish ionic transport kinetics and the unstable electrode structure during ionic insertion/extraction hampers their deployment. Herein,  we propose a new cathode material based on a layered metal chalcogenide (LMC), bismuth telluride (Bi<jats:sub>2</jats:sub>Te<jats:sub>3</jats:sub>), coated with polypyrrole (PPy). Taking advantage of the PPy coating, the Bi<jats:sub>2</jats:sub>Te<jats:sub>3</jats:sub>@PPy composite presents strong ionic absorption affinity, high oxidation resistance, and high structural stability. The ZIBs based on Bi<jats:sub>2</jats:sub>Te<jats:sub>3</jats:sub>@PPy cathodes exhibit high capacities and ultra‐long lifespans of over 5000 cycles. They also present outstanding stability even under bending. In addition,  we analyze here the reaction mechanism using in situ X‐ray diffraction, X‐ray photoelectron spectroscopy, and computational tools and demonstrate that, in the aqueous system, Zn<jats:sup>2+</jats:sup> is not inserted into the cathode as previously assumed. In contrast, proton charge storage dominates the process. Overall, this work not only shows the great potential of LMCs as ZIBs cathode materials and the advantages of PPy coating, but also clarifies the charge/discharge mechanism in rechargeable ZIBs based on LMCs.","lang":"eng"}],"date_created":"2023-10-17T10:53:56Z","article_processing_charge":"No","doi":"10.1002/adma.202305128","publication_status":"published","publication_identifier":{"issn":["0935-9648"],"eissn":["1521-4095"]},"oa_version":"None","publisher":"Wiley","supplementarymaterial":"yes","_id":"14435","title":"A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries","article_type":"original","acknowledged_ssus":[{"_id":"EM-Fac"}],"das_tickbox":"1","date_published":"2024-01-04T00:00:00Z","month":"01","volume":36},{"scopus_import":"1","fulldoi":"https://doi.org/10.1021/acsaem.3c02519","day":"08","date_updated":"2026-10-16T09:20:00Z","issue":"1","page":"214-229","status":"public","type":"journal_article","department":[{"_id":"MaIb"}],"year":"2024","keyword":["Electrical and Electronic Engineering","Materials Chemistry","Electrochemistry","Energy Engineering and Power Technology","Chemical Engineering (miscellaneous)"],"researchdata_availability":"no","quality_controlled":"1","acknowledgement":"This work was supported by the Technology Innovation Program (20011622, Development of Battery System Applied High-Efficiency Heat Control Polymer and Part Component) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea). Author acknowledge to Prof. Tsunehiro Takeuchi from Toyota Technological Institute, Nagoya, Japan for the support of computational resources.","title":"Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity","article_type":"original","publisher":"American Chemical Society","supplementarymaterial":"yes","_id":"14828","das_tickbox":"0","date_published":"2024-01-08T00:00:00Z","volume":7,"month":"01","language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","corr_author":"1","isi":1,"citation":{"short":"G.K. Kiran, S. Singh, N. Mahato, T.V.M. Sreekanth, G.R. Dillip, K. Yoo, J. Kim, ACS Applied Energy Materials 7 (2024) 214–229.","ama":"Kiran GK, Singh S, Mahato N, et al. Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. <i>ACS Applied Energy Materials</i>. 2024;7(1):214-229. doi:<a href=\"https://doi.org/10.1021/acsaem.3c02519\">10.1021/acsaem.3c02519</a>","chicago":"Kiran, Gundegowda Kalligowdanadoddi, Saurabh Singh, Neelima Mahato, Thupakula Venkata Madhukar Sreekanth, Gowra Raghupathy Dillip, Kisoo Yoo, and Jonghoon Kim. “Interface Engineering Modulation Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity.” <i>ACS Applied Energy Materials</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/acsaem.3c02519\">https://doi.org/10.1021/acsaem.3c02519</a>.","ieee":"G. K. Kiran <i>et al.</i>, “Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity,” <i>ACS Applied Energy Materials</i>, vol. 7, no. 1. American Chemical Society, pp. 214–229, 2024.","ista":"Kiran GK, Singh S, Mahato N, Sreekanth TVM, Dillip GR, Yoo K, Kim J. 2024. Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. ACS Applied Energy Materials. 7(1), 214–229.","mla":"Kiran, Gundegowda Kalligowdanadoddi, et al. “Interface Engineering Modulation Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity.” <i>ACS Applied Energy Materials</i>, vol. 7, no. 1, American Chemical Society, 2024, pp. 214–29, doi:<a href=\"https://doi.org/10.1021/acsaem.3c02519\">10.1021/acsaem.3c02519</a>.","apa":"Kiran, G. K., Singh, S., Mahato, N., Sreekanth, T. V. M., Dillip, G. R., Yoo, K., &#38; Kim, J. (2024). Interface engineering modulation combined with electronic structure modification of Zn-doped NiO heterostructure for efficient water-splitting activity. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaem.3c02519\">https://doi.org/10.1021/acsaem.3c02519</a>"},"intvolume":"         7","publication":"ACS Applied Energy Materials","doi":"10.1021/acsaem.3c02519","date_created":"2024-01-17T12:48:35Z","publication_status":"published","article_processing_charge":"No","publication_identifier":{"issn":["2574-0962"]},"oa_version":"None","author":[{"last_name":"Kiran","first_name":"Gundegowda Kalligowdanadoddi","full_name":"Kiran, Gundegowda Kalligowdanadoddi"},{"last_name":"Singh","first_name":"Saurabh","full_name":"Singh, Saurabh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","orcid":"0000-0003-2209-5269"},{"full_name":"Mahato, Neelima","first_name":"Neelima","last_name":"Mahato"},{"last_name":"Sreekanth","first_name":"Thupakula Venkata Madhukar","full_name":"Sreekanth, Thupakula Venkata Madhukar"},{"first_name":"Gowra Raghupathy","full_name":"Dillip, Gowra Raghupathy","last_name":"Dillip"},{"first_name":"Kisoo","full_name":"Yoo, Kisoo","last_name":"Yoo"},{"first_name":"Jonghoon","full_name":"Kim, Jonghoon","last_name":"Kim"}],"abstract":[{"lang":"eng","text":"Production of hydrogen at large scale requires development of non-noble, inexpensive, and high-performing catalysts for constructing water-splitting devices. Herein, we report the synthesis of Zn-doped NiO heterostructure (ZnNiO) catalysts at room temperature via a coprecipitation method followed by drying (at 80 °C, 6 h) and calcination at an elevated temperature of 400 °C for 5 h under three distinct conditions, namely, air, N2, and vacuum. The vacuum-synthesized catalyst demonstrates a low overpotential of 88 mV at −10 mA cm–2 and a small Tafel slope of 73 mV dec–1 suggesting relatively higher charge transfer kinetics for hydrogen evolution reactions (HER) compared with the specimens synthesized under N2 or O2 atmosphere. It also demonstrates an oxygen evolution (OER) overpotential of 260 mV at 10 mA cm–2 with a low Tafel slope of 63 mV dec–1. In a full-cell water-splitting device, the vacuum-synthesized ZnNiO heterostructure demonstrates a cell voltage of 1.94 V at 50 mA cm–2 and shows remarkable stability over 24 h at a high current density of 100 mA cm–2. It is also demonstrated in this study that Zn-doping, surface, and interface engineering in transition-metal oxides play a crucial role in efficient electrocatalytic water splitting. Also, the results obtained from density functional theory (DFT + U = 0–8 eV), where U is the on-site Coulomb repulsion parameter also known as Hubbard U, based electronic structure calculations confirm that Zn doping constructively modifies the electronic structure, in both the valence band and the conduction band, and found to be suitable in tailoring the carrier’s effective masses of electrons and holes. The decrease in electron’s effective masses together with large differences between the effective masses of electrons and holes is noticed, which is found to be mainly responsible for achieving the best water-splitting performance from a 9% Zn-doped NiO sample prepared under vacuum."}],"external_id":{"isi":["001138342900001"]}},{"publication":"Chemical Engineering Science","citation":{"ama":"Yao Z, Liu X, Bunting R, Wang J. Unravelling the reaction mechanism for H2 production via formic acid decomposition over Pd: Coverage-dependent microkinetic modeling. <i>Chemical Engineering Science</i>. 2024;291. doi:<a href=\"https://doi.org/10.1016/j.ces.2024.119959\">10.1016/j.ces.2024.119959</a>","short":"Z. Yao, X. Liu, R. Bunting, J. Wang, Chemical Engineering Science 291 (2024).","ista":"Yao Z, Liu X, Bunting R, Wang J. 2024. Unravelling the reaction mechanism for H2 production via formic acid decomposition over Pd: Coverage-dependent microkinetic modeling. Chemical Engineering Science. 291, 119959.","ieee":"Z. Yao, X. Liu, R. Bunting, and J. Wang, “Unravelling the reaction mechanism for H2 production via formic acid decomposition over Pd: Coverage-dependent microkinetic modeling,” <i>Chemical Engineering Science</i>, vol. 291. Elsevier, 2024.","chicago":"Yao, Zihao, Xu Liu, Rhys Bunting, and Jianguo Wang. “Unravelling the Reaction Mechanism for H2 Production via Formic Acid Decomposition over Pd: Coverage-Dependent Microkinetic Modeling.” <i>Chemical Engineering Science</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.ces.2024.119959\">https://doi.org/10.1016/j.ces.2024.119959</a>.","mla":"Yao, Zihao, et al. “Unravelling the Reaction Mechanism for H2 Production via Formic Acid Decomposition over Pd: Coverage-Dependent Microkinetic Modeling.” <i>Chemical Engineering Science</i>, vol. 291, 119959, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.ces.2024.119959\">10.1016/j.ces.2024.119959</a>.","apa":"Yao, Z., Liu, X., Bunting, R., &#38; Wang, J. (2024). Unravelling the reaction mechanism for H2 production via formic acid decomposition over Pd: Coverage-dependent microkinetic modeling. <i>Chemical Engineering Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ces.2024.119959\">https://doi.org/10.1016/j.ces.2024.119959</a>"},"intvolume":"       291","language":[{"iso":"eng"}],"isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_number":"119959","external_id":{"isi":["001203872000001"]},"abstract":[{"lang":"eng","text":"As a key liquid organic hydrogen carrier, investigating the decomposition of formic acid (HCOOH) on the Pd (1 1 1) transition metal surface is imperative for harnessing hydrogen energy. Despite a multitude of studies, the major mechanisms and key intermediates involved in the dehydrogenation process of formic acid remain a great topic of debate due to ambiguous adsorbate interactions. In this research, we develop an advanced microkinetic model based on first-principles calculations, accounting for adsorbate–adsorbate interactions. Our study unveils a comprehensive mechanism for the Pd (1 1 1) surface, highlighting the significance of coverage effects in formic acid dehydrogenation. Our findings unequivocally demonstrate that H coverage on the Pd (1 1 1) surface renders formic acid more susceptible to decompose into H2 and CO2 through COOH intermediates. Consistent with experimental results, the selectivity of H2 in the decomposition of formic acid on the Pd (1 1 1) surface approaches 100 %. Considering the influence of H coverage, our kinetic analysis aligns perfectly with experimental values at a temperature of 373 K."}],"author":[{"last_name":"Yao","full_name":"Yao, Zihao","first_name":"Zihao"},{"first_name":"Xu","full_name":"Liu, Xu","last_name":"Liu"},{"orcid":"0000-0001-6928-074X","id":"91deeae8-1207-11ec-b130-c194ad5b50c6","first_name":"Rhys","full_name":"Bunting, Rhys","last_name":"Bunting"},{"last_name":"Wang","full_name":"Wang, Jianguo","first_name":"Jianguo"}],"doi":"10.1016/j.ces.2024.119959","publication_status":"published","date_created":"2024-03-17T23:00:57Z","article_processing_charge":"No","oa_version":"None","publication_identifier":{"issn":["0009-2509"]},"publisher":"Elsevier","supplementarymaterial":"yes","_id":"15114","title":"Unravelling the reaction mechanism for H2 production via formic acid decomposition over Pd: Coverage-dependent microkinetic modeling","article_type":"original","main_file_link":[{"url":"https://doi.org/10.1016/j.ces.2024.119959","open_access":"1"}],"oa":1,"date_published":"2024-06-05T00:00:00Z","das_tickbox":"1","volume":291,"month":"06","dataavailabilitystatement":"Data will be made available on request.","department":[{"_id":"MaIb"}],"year":"2024","acknowledgement":"The authors acknowledge the financial support from the National Key Research and Development Project of China (2021YFA1500900, 2022YFE0113800), the National Natural Science Foundation of China (22141001, U21A20298), Zhejiang Innovation Team (2017R5203).","quality_controlled":"1","researchdata_availability":"upon request","OA_type":"free access","day":"05","date_updated":"2026-10-16T09:20:35Z","fulldoi":"https://doi.org/10.1016/j.ces.2024.119959","scopus_import":"1","status":"public","type":"journal_article"},{"volume":674,"month":"02","date_published":"2024-02-01T00:00:00Z","das_tickbox":"1","article_type":"original","title":"Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys","_id":"14652","supplementarymaterial":"no","publisher":"Elsevier","oa_version":"None","publication_identifier":{"issn":["0921-4526"]},"date_created":"2023-12-10T23:00:56Z","article_processing_charge":"No","publication_status":"published","doi":"10.1016/j.physb.2023.415539","author":[{"last_name":"Gupta","full_name":"Gupta, Shyam Lal","first_name":"Shyam Lal"},{"last_name":"Singh","orcid":"0000-0003-2209-5269","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","full_name":"Singh, Saurabh","first_name":"Saurabh"},{"last_name":"Kumar","full_name":"Kumar, Sumit","first_name":"Sumit"},{"first_name":"Unknown","full_name":"Anupam, Unknown","last_name":"Anupam"},{"last_name":"Thakur","full_name":"Thakur, Samjeet Singh","first_name":"Samjeet Singh"},{"first_name":"Ashish","full_name":"Kumar, Ashish","last_name":"Kumar"},{"first_name":"Sanjay","full_name":"Panwar, Sanjay","last_name":"Panwar"},{"last_name":"Diwaker","first_name":"D.","full_name":"Diwaker, D."}],"abstract":[{"text":"In order to demonstrate the stability of newly proposed iridium-based Ir2Cr(In,Sn) and IrRhCr(In,Sn) heusler alloys, we present ab-initio analysis of these alloys by examining various properties to prove their stability. The stability of these alloys can be inferred from different cohesive and formation energies as well as positive phonon frequencies. Their electronic structure results indicate that they are semi-metals in nature. The magnetic moments are computed using the Slater-Pauling formula and exhibit a high value, with the Cr atom contributing the most in all alloys. Mulliken’s charge analysis results show that our alloys contain a range of linkages, mainly ionic and covalent ones. The ductility and mechanical stability of these alloys are confirmed by elastic constants viz. Poisson’s ratio, Pugh’s ratio, and many different types of elastic moduli.","lang":"eng"}],"external_id":{"isi":["001127429000001"]},"article_number":"415539","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"language":[{"iso":"eng"}],"citation":{"ieee":"S. L. Gupta <i>et al.</i>, “Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys,” <i>Physica B: Condensed Matter</i>, vol. 674, no. 2. Elsevier, 2024.","chicago":"Gupta, Shyam Lal, Saurabh Singh, Sumit Kumar, Unknown Anupam, Samjeet Singh Thakur, Ashish Kumar, Sanjay Panwar, and D. Diwaker. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” <i>Physica B: Condensed Matter</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.physb.2023.415539\">https://doi.org/10.1016/j.physb.2023.415539</a>.","ista":"Gupta SL, Singh S, Kumar S, Anupam U, Thakur SS, Kumar A, Panwar S, Diwaker D. 2024. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 674(2), 415539.","short":"S.L. Gupta, S. Singh, S. Kumar, U. Anupam, S.S. Thakur, A. Kumar, S. Panwar, D. Diwaker, Physica B: Condensed Matter 674 (2024).","ama":"Gupta SL, Singh S, Kumar S, et al. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. <i>Physica B: Condensed Matter</i>. 2024;674(2). doi:<a href=\"https://doi.org/10.1016/j.physb.2023.415539\">10.1016/j.physb.2023.415539</a>","mla":"Gupta, Shyam Lal, et al. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” <i>Physica B: Condensed Matter</i>, vol. 674, no. 2, 415539, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.physb.2023.415539\">10.1016/j.physb.2023.415539</a>.","apa":"Gupta, S. L., Singh, S., Kumar, S., Anupam, U., Thakur, S. S., Kumar, A., … Diwaker, D. (2024). Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. <i>Physica B: Condensed Matter</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.physb.2023.415539\">https://doi.org/10.1016/j.physb.2023.415539</a>"},"intvolume":"       674","publication":"Physica B: Condensed Matter","issue":"2","type":"journal_article","status":"public","scopus_import":"1","fulldoi":"https://doi.org/10.1016/j.physb.2023.415539","date_updated":"2026-10-16T09:19:32Z","day":"01","researchdata_availability":"not applicable","quality_controlled":"1","year":"2024","department":[{"_id":"MaIb"}],"dataavailabilitystatement":"No data was used for the research described in the article."},{"citation":{"apa":"Tang, X. (2024). The interaction between the DSC2 and the asymmetric lipids. Zenodo. <a href=\"https://doi.org/10.5281/zenodo.13889575\">https://doi.org/10.5281/zenodo.13889575</a>","mla":"Tang, Xuechen. <i>The Interaction between the DSC2 and the Asymmetric Lipids</i>. Zenodo, 2024, doi:<a href=\"https://doi.org/10.5281/zenodo.13889575\">10.5281/zenodo.13889575</a>.","chicago":"Tang, Xuechen. “The Interaction between the DSC2 and the Asymmetric Lipids.” Zenodo, 2024. <a href=\"https://doi.org/10.5281/zenodo.13889575\">https://doi.org/10.5281/zenodo.13889575</a>.","ieee":"X. Tang, “The interaction between the DSC2 and the asymmetric lipids.” Zenodo, 2024.","ista":"Tang X. 2024. The interaction between the DSC2 and the asymmetric lipids, Zenodo, <a href=\"https://doi.org/10.5281/zenodo.13889575\">10.5281/zenodo.13889575</a>.","ama":"Tang X. The interaction between the DSC2 and the asymmetric lipids. 2024. doi:<a href=\"https://doi.org/10.5281/zenodo.13889575\">10.5281/zenodo.13889575</a>","short":"X. Tang, (2024)."},"related_material":{"record":[{"relation":"used_in_publication","id":"18522","status":"public"}]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","author":[{"first_name":"Xuechen","full_name":"Tang, Xuechen","last_name":"Tang"}],"abstract":[{"text":"The attached trajectories illustrate the preference for the association of saturated asymmetric lipids over unsaturated ones with DSC2. In order to comply with the size limit, the initial conformations as well as one illustrative example of the final productive simulation with complete number of frames and all others sliced by 100 frames of each simulated system are provided herewith. Two illustrative example trajectories in the equilibrated but not yet converged phases are attached in additon, to demonstrate the dynamic rearrangement of asymmetric lipids before the stable states. The first example is that of the saturated asymmetric lipid, which is used to illustrate the association of the trucated saturated chain with the DSC2. The second example depicts the dissociation of an analogous unsaturated chain from the DSC2. The initial conformations are provided in PDB format, while the final productive simulations are uploaded in NetCDF (AMBER) format. ","lang":"eng"}],"article_processing_charge":"No","date_created":"2026-10-16T09:14:55Z","doi":"10.5281/zenodo.13889575","OA_type":"green","oa_version":"None","publisher":"Zenodo","fulldoi":"https://doi.org/10.5281/zenodo.13889575","day":"04","_id":"23144","date_updated":"2026-10-16T09:15:19Z","title":"The interaction between the DSC2 and the asymmetric lipids","ddc":["570"],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/zenodo.13889575"}],"status":"public","type":"research_data_reference","date_published":"2024-10-04T00:00:00Z","OA_place":"repository","oa":1,"month":"10"},{"title":"Unveiling crucial chemical processing parameters influencing the performance of solution-processed inorganic thermoelectric materials","article_type":"original","publisher":"Wiley","supplementarymaterial":"yes","_id":"17052","das_tickbox":"1","OA_place":"publisher","date_published":"2024-06-17T00:00:00Z","oa":1,"month":"06","volume":63,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NMR"},{"_id":"LifeSc"}],"related_material":{"record":[{"id":"22626","status":"public","relation":"dissertation_contains"}]},"language":[{"iso":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","corr_author":"1","isi":1,"intvolume":"        63","citation":{"mla":"Fiedler, Christine, et al. “Unveiling Crucial Chemical Processing Parameters Influencing the Performance of Solution-Processed Inorganic Thermoelectric Materials.” <i>Angewandte Chemie International Edition</i>, vol. 63, no. 25, e202402628, Wiley, 2024, doi:<a href=\"https://doi.org/10.1002/anie.202402628\">10.1002/anie.202402628</a>.","apa":"Fiedler, C., Calcabrini, M., Liu, Y., &#38; Ibáñez, M. (2024). Unveiling crucial chemical processing parameters influencing the performance of solution-processed inorganic thermoelectric materials. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202402628\">https://doi.org/10.1002/anie.202402628</a>","short":"C. Fiedler, M. Calcabrini, Y. Liu, M. Ibáñez, Angewandte Chemie International Edition 63 (2024).","ama":"Fiedler C, Calcabrini M, Liu Y, Ibáñez M. Unveiling crucial chemical processing parameters influencing the performance of solution-processed inorganic thermoelectric materials. <i>Angewandte Chemie International Edition</i>. 2024;63(25). doi:<a href=\"https://doi.org/10.1002/anie.202402628\">10.1002/anie.202402628</a>","ieee":"C. Fiedler, M. Calcabrini, Y. Liu, and M. Ibáñez, “Unveiling crucial chemical processing parameters influencing the performance of solution-processed inorganic thermoelectric materials,” <i>Angewandte Chemie International Edition</i>, vol. 63, no. 25. Wiley, 2024.","ista":"Fiedler C, Calcabrini M, Liu Y, Ibáñez M. 2024. Unveiling crucial chemical processing parameters influencing the performance of solution-processed inorganic thermoelectric materials. Angewandte Chemie International Edition. 63(25), e202402628.","chicago":"Fiedler, Christine, Mariano Calcabrini, Yu Liu, and Maria Ibáñez. “Unveiling Crucial Chemical Processing Parameters Influencing the Performance of Solution-Processed Inorganic Thermoelectric Materials.” <i>Angewandte Chemie International Edition</i>. Wiley, 2024. <a href=\"https://doi.org/10.1002/anie.202402628\">https://doi.org/10.1002/anie.202402628</a>."},"publication":"Angewandte Chemie International Edition","doi":"10.1002/anie.202402628","article_processing_charge":"Yes (via OA deal)","publication_status":"published","date_created":"2024-05-26T22:00:58Z","publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"oa_version":"Published Version","article_number":"e202402628","file_date_updated":"2025-01-09T09:12:07Z","abstract":[{"text":"Production of thermoelectric materials from solution-processed particles involves the synthesis of particles, their purification and densification into pelletized material. Chemical changes that occur during each one of these steps render them performance determining. Particularly the purification steps, bypassed in conventional solid-state synthesis, are the cause for large discrepancies among similar solution-processed materials. In present work, the investigation focuses on a water-based surfactant free solution synthesis of SnSe, a highly relevant thermoelectric material. We show and rationalize that the number of leaching steps, purification solvent, annealing, and annealing atmosphere have significant influence on the Sn : Se ratio and impurity content in the powder. Such compositional changes that are undetectable by conventional characterization techniques lead to distinct consolidated materials with different types and concentration of defects. Additionally, the profound effect on their transport properties is demonstrated. We emphasize that understanding the chemistry and identifying key chemical species and their role throughout the process is paramount for optimizing material performance. Furthermore, we aim to demonstrate the necessity of comprehensive reporting of these steps as a standard practice to ensure material reproducibility.","lang":"eng"}],"author":[{"full_name":"Fiedler, Christine","first_name":"Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","last_name":"Fiedler"},{"orcid":"0000-0003-4566-5877","id":"45D7531A-F248-11E8-B48F-1D18A9856A87","first_name":"Mariano","full_name":"Calcabrini, Mariano","last_name":"Calcabrini"},{"first_name":"Yu","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","last_name":"Liu"},{"last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","first_name":"Maria"}],"external_id":{"isi":["001223768400001"],"pmid":["38623865"]},"ddc":["540"],"scopus_import":"1","pmid":1,"fulldoi":"https://doi.org/10.1002/anie.202402628","day":"17","date_updated":"2026-10-16T09:30:27Z","issue":"25","ec_funded":1,"project":[{"call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program","grant_number":"665385","call_identifier":"H2020"},{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"has_accepted_license":"1","status":"public","type":"journal_article","department":[{"_id":"MaIb"}],"dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author upon reasonable request.","file":[{"content_type":"application/pdf","relation":"main_file","file_name":"2024_AngewChemieIntern_Fiedler.pdf","creator":"dernst","date_updated":"2025-01-09T09:12:07Z","file_size":16347226,"date_created":"2025-01-09T09:12:07Z","access_level":"open_access","file_id":"18797","checksum":"1572a0f4d2df55751761efeb2d11c7fc","success":1}],"year":"2024","OA_type":"hybrid","researchdata_availability":"upon request","quality_controlled":"1","acknowledgement":"ISTA and the Werner Siemens Foundation financially supported this work. The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF), NMR Facility and the Lab Support Facility (LSF). Dr. Krishnendu Maji at ISTA aided in this work through XRD analysis of the crystal phase of SnSe. Y.L. acknowledges funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411, the National Natural Science Foundation of China (NSFC) (Grants No. 22209034). M.C. received funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 665385."}]