[{"type":"research_data","acknowledgement":"We thank Nikolai R. Skrynnikov and Olga O. Lebedenko (St. Petersburg) for insightful discussions and for performing exploratory MD simulations. We are grateful to Tobias Schubeis (Lyon) for advice with GB1 crystallization, and Rebecca Schmid for initial crystallization trials.\r\nWe thank Sebastian Falkner for assistance with constructing the structural model of the IgG:GB1 complex.\r\nThis research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra Rovó and Margarita Valhondo Falcón for excellent support of the NMR facility.\r\nLea M. Becker is recipient of a DOC fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (grant no. PR10660EAW01). Christophe Chipot acknowledges the European Research Council (grant project 101097272 ``MilliInMicro'') and the Métropole du Grand Nancy (grant project ``ARC''). BM07-FIP2 is supported by the French ANR PIA3 (France 2030) EquipEx+ project MAGNIFIX under grant agreement ANR-21-ESRE-0011.","status":"public","doi":"10.15479/AT-ISTA-21145","has_accepted_license":"1","related_material":{"record":[{"id":"20641","status":"public","relation":"earlier_version"}]},"year":"2026","oa":1,"file":[{"file_name":"README.txt","date_updated":"2026-02-05T13:52:37Z","checksum":"02a419cce8cea450bc952f35488d2df5","file_size":4263,"content_type":"text/plain","date_created":"2026-02-05T13:52:37Z","relation":"table_of_contents","access_level":"open_access","creator":"lbecker","file_id":"21146"},{"date_created":"2026-02-05T13:52:41Z","relation":"main_file","date_updated":"2026-02-05T13:52:41Z","file_name":"Research_Data.zip","content_type":"application/zip","checksum":"b0b82b1aa73985b0b308a3fa52d21aea","file_size":50647107,"file_id":"21147","access_level":"open_access","creator":"lbecker","success":1}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"contributor":[{"contributor_type":"researcher","first_name":"Haohao","last_name":"Fu"},{"id":"71cda2f3-e604-11ee-a1df-da10587eda3f","first_name":"Benjamin","last_name":"Tatman","contributor_type":"researcher"},{"contributor_type":"researcher","last_name":"Dreydoppel","first_name":"Matthias"},{"contributor_type":"researcher","last_name":"Kapitonova","first_name":"Anna","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471"},{"first_name":"Daniel","last_name":"Balazs","contributor_type":"researcher","orcid":"0000-0001-7597-043X","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E"},{"contributor_type":"researcher","first_name":"Ulrich","last_name":"Weininger"},{"last_name":"Engilberge","first_name":"Sylvain","contributor_type":"researcher"}],"month":"02","day":"09","_id":"21145","oa_version":"Published Version","article_processing_charge":"No","department":[{"_id":"GradSch"},{"_id":"PaSc"}],"acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"publisher":"Institute of Science and Technology Austria","citation":{"chicago":"Becker, Lea Marie, Paul Schanda, and Christophe Chipot. “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21145.","apa":"Becker, L. M., Schanda, P., & Chipot, C. (2026). Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21145","ama":"Becker LM, Schanda P, Chipot C. Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” 2026. doi:10.15479/AT-ISTA-21145","ieee":"L. M. Becker, P. Schanda, and C. Chipot, “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026.","short":"L.M. Becker, P. Schanda, C. Chipot, (2026).","mla":"Becker, Lea Marie, et al. Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21145.","ista":"Becker LM, Schanda P, Chipot C. 2026. Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21145."},"ddc":["572"],"date_published":"2026-02-09T00:00:00Z","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-02-05T13:52:41Z","date_updated":"2026-06-10T08:25:16Z","abstract":[{"lang":"eng","text":"Protein conformational energy landscapes are shaped not only by intramolecular interactions but also by their environment. In protein crystals and protein-protein complexes, intermolecular contacts alter this energy landscape, but the exact nature of this alteration is difficult to decipher. Understanding how the crystal lattice affects protein dynamics is crucial for crystallography-based studies of motion, yet its influence on collective motions remains unclear. Aromatic ring flips in the hydrophobic core represent sensitive probes of such dynamics. Here, we compare the kinetics of aromatic ring flips in the protein GB1 in crystals, in complex with its binding partner IgG, and in solution, combining advanced isotope labeling with quantitative NMR methods. We show that rings in the core flip nearly a thousand times less frequently in crystals than in solution. Enhanced-sampling molecular dynamics simulations, based on a new crystal structure, reproduce these elevated barriers and reveal how the crystal restrains motions. "}],"project":[{"_id":"7be609c4-9f16-11ee-852c-85015ce2b9b0","name":"Exploring protein dynamics by solid-state MAS NMR through specific labeling approaches","grant_number":"26777"}],"date_created":"2026-02-05T13:54:39Z","title":"Additional Data for \"Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes\"","author":[{"id":"36336939-eb97-11eb-a6c2-c83f1214ca79","full_name":"Becker, Lea Marie","orcid":"0000-0002-6401-5151","first_name":"Lea Marie","last_name":"Becker"},{"first_name":"Paul","last_name":"Schanda","orcid":"0000-0002-9350-7606","full_name":"Schanda, Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425"},{"last_name":"Chipot","first_name":"Christophe","full_name":"Chipot, Christophe"}]},{"article_number":"80","corr_author":"1","OA_type":"gold","date_published":"2026-03-04T00:00:00Z","file_date_updated":"2026-03-16T10:07:46Z","publication":"Communications Physics","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","abstract":[{"text":"Probing the possibility of entanglement generation through gravity offers a path to tackle the question of whether gravitational fields possess a quantum mechanical nature. A potential realization necessitates systems with low-frequency dynamics at an optimal mass scale, for which the microgram-to-milligram range is a strong contender. Here, after refining a figure-of-merit for the problem, we present a 1-milligram torsional pendulum operating at 18 Hz. We demonstrate laser cooling its motion from room temperature to 240 microkelvins, surpassing by over 20-fold the coldest motions attained for oscillators ranging from micrograms to kilograms. We quantify and contrast the utility of the current approach with other platforms. The achieved performance and large improvement potential highlight milligram-scale torsional pendulums as a powerful platform for precision measurements relevant to future studies at the quantum-gravity interface.","lang":"eng"}],"date_updated":"2026-06-10T08:36:06Z","external_id":{"arxiv":["2408.09445"]},"date_created":"2025-12-21T11:39:04Z","title":"One-milligram torsional pendulum toward experiments at the quantum-gravity interface","author":[{"first_name":"Sofya","last_name":"Agafonova","orcid":"0000-0003-0582-2946","full_name":"Agafonova, Sofya","id":"09501ff6-dca7-11ea-a8ae-b3e0b9166e80"},{"first_name":"Pere","last_name":"Rosello","full_name":"Rosello, Pere"},{"last_name":"Mekonnen","first_name":"Manuel","full_name":"Mekonnen, Manuel"},{"full_name":"Hosten, Onur","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","last_name":"Hosten","first_name":"Onur","orcid":"0000-0002-2031-204X"}],"project":[{"_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6","name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics","grant_number":"101087907"}],"_id":"20840","article_processing_charge":"Yes","oa_version":"Published Version","day":"04","intvolume":" 9","department":[{"_id":"GradSch"},{"_id":"OnHo"}],"article_type":"original","scopus_import":"1","publisher":"Springer Nature","ddc":["530"],"quality_controlled":"1","citation":{"ama":"Agafonova S, Rosello P, Mekonnen M, Hosten O. One-milligram torsional pendulum toward experiments at the quantum-gravity interface. Communications Physics. 2026;9. doi:10.1038/s42005-026-02514-w","apa":"Agafonova, S., Rosello, P., Mekonnen, M., & Hosten, O. (2026). One-milligram torsional pendulum toward experiments at the quantum-gravity interface. Communications Physics. Springer Nature. https://doi.org/10.1038/s42005-026-02514-w","chicago":"Agafonova, Sofia, Pere Rosello, Manuel Mekonnen, and Onur Hosten. “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.” Communications Physics. Springer Nature, 2026. https://doi.org/10.1038/s42005-026-02514-w.","ista":"Agafonova S, Rosello P, Mekonnen M, Hosten O. 2026. One-milligram torsional pendulum toward experiments at the quantum-gravity interface. Communications Physics. 9, 80.","ieee":"S. Agafonova, P. Rosello, M. Mekonnen, and O. Hosten, “One-milligram torsional pendulum toward experiments at the quantum-gravity interface,” Communications Physics, vol. 9. Springer Nature, 2026.","short":"S. Agafonova, P. Rosello, M. Mekonnen, O. Hosten, Communications Physics 9 (2026).","mla":"Agafonova, Sofia, et al. “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.” Communications Physics, vol. 9, 80, Springer Nature, 2026, doi:10.1038/s42005-026-02514-w."},"doi":"10.1038/s42005-026-02514-w","PlanS_conform":"1","related_material":{"record":[{"status":"public","id":"20842","relation":"research_data"}]},"has_accepted_license":"1","language":[{"iso":"eng"}],"file":[{"file_size":1901772,"content_type":"application/pdf","checksum":"62e2175e7e3ad49260ae6a7b4e0860a2","file_name":"2026_CommunicationsPhysics_Agafonova.pdf","date_updated":"2026-03-16T10:07:46Z","date_created":"2026-03-16T10:07:46Z","relation":"main_file","access_level":"open_access","success":1,"creator":"dernst","file_id":"21457"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2026","oa":1,"DOAJ_listed":"1","arxiv":1,"month":"03","type":"journal_article","acknowledgement":"We thank Gerard Higgins, Andrei Militaru, Nikolai Kiesel, and Markus Aspelmeyer for useful discussions on the topic of the figure-of-merit. We thank Teodor Strömberg for helping with the additional characterizations of the optical lever noise. We thank Johannes Fink and Scott Waitukaitis for their helpful feedback on the manuscript. This work was supported by Institute of Science and Technology Austria and the European Research Council under Grant No. 101087907 (ERC CoG QuHAMP).","status":"public","publication_identifier":{"eissn":["2399-3650"]},"volume":9,"OA_place":"publisher"},{"year":"2026","oa":1,"file":[{"relation":"main_file","date_created":"2026-02-17T10:11:14Z","date_updated":"2026-02-17T10:11:14Z","file_name":"Research_data.zip","content_type":"application/zip","checksum":"2d3105f26be578073b88ee1f2ea0bdb1","file_size":36996027,"file_id":"21285","creator":"lbecker","success":1,"access_level":"open_access"},{"access_level":"open_access","creator":"lbecker","file_id":"21286","file_name":"README.txt","date_updated":"2026-02-17T10:11:14Z","checksum":"e24aebcdb8856cb181cbaa02de020ddb","content_type":"text/plain","file_size":1993,"date_created":"2026-02-17T10:11:14Z","relation":"table_of_contents"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"doi":"10.15479/AT-ISTA-21284","has_accepted_license":"1","month":"2","contributor":[{"id":"334a5e40-8747-11f0-b671-ba1f5154b4b4","contributor_type":"researcher","first_name":"Giorgia","last_name":"Toscano"},{"id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471","contributor_type":"researcher","first_name":"Anna","last_name":"Kapitonova"},{"id":"a3089acd-6806-11ee-bacc-f0c7d500ad20","last_name":"Singh","first_name":"Rajkumar","contributor_type":"researcher"},{"id":"bb74f472-ae54-11eb-9835-bc9c22fb1183","last_name":"Guillerm","first_name":"Undina","contributor_type":"researcher"},{"contributor_type":"researcher","last_name":"Lichtenecker","first_name":"Roman"}],"acknowledgement":"We thank Ben P. Tatman for insightful discussions. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support Facility.","type":"research_data","OA_place":"repository","status":"public","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","file_date_updated":"2026-02-17T10:11:14Z","OA_type":"free access","date_published":"2026-02-18T00:00:00Z","corr_author":"1","date_created":"2026-02-17T10:17:14Z","title":"Research data for \"Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants\"","author":[{"id":"36336939-eb97-11eb-a6c2-c83f1214ca79","full_name":"Becker, Lea Marie","orcid":"0000-0002-6401-5151","last_name":"Becker","first_name":"Lea Marie"},{"orcid":"0000-0002-9350-7606","first_name":"Paul","last_name":"Schanda","full_name":"Schanda, Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425"}],"date_updated":"2026-06-10T09:28:41Z","abstract":[{"lang":"eng","text":"The advantageous characteristics attributed to the 19F nucleus have made it a popular target for NMR once again in recent years. Aside from solution NMR, an increasing number of studies have been conducted applying solid-state magic-angle-spinning NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and strong dipolar couplings can be utilized to get structural insights into proteins and measure long distances. Despite increasing popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and 13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially reduces measurement times of 19F MAS NMR experiments without compromising resolution. Additionally, we report the chemical-shift assignments of all four fluorotryptophan signals in the 12 × 39 kDa large protein using a mutagenesis approach."}],"department":[{"_id":"GradSch"},{"_id":"PaSc"}],"day":"18","_id":"21284","article_processing_charge":"No","oa_version":"Published Version","citation":{"chicago":"Becker, Lea Marie, and Paul Schanda. “Research Data for ‘Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21284.","ama":"Becker LM, Schanda P. Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” 2026. doi:10.15479/AT-ISTA-21284","apa":"Becker, L. M., & Schanda, P. (2026). Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21284","ieee":"L. M. Becker and P. Schanda, “Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.’” Institute of Science and Technology Austria, 2026.","short":"L.M. Becker, P. Schanda, (2026).","mla":"Becker, Lea Marie, and Paul Schanda. Research Data for “Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21284.","ista":"Becker LM, Schanda P. 2026. Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21284."},"ddc":["541"],"acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"publisher":"Institute of Science and Technology Austria"},{"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication_status":"published","file_date_updated":"2026-03-02T10:59:50Z","date_published":"2026-02-26T00:00:00Z","corr_author":"1","project":[{"grant_number":"101060393","name":"Breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks","_id":"34afa094-11ca-11ed-8bc3-a375845a59fb"}],"date_created":"2026-02-27T09:08:14Z","author":[{"id":"FF6018E0-D806-11E9-8E43-0B14E6697425","full_name":"Riegler, Stefan","orcid":"0000-0003-3413-1343","first_name":"Stefan","last_name":"Riegler"}],"title":"Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species","date_updated":"2026-06-10T09:39:12Z","alternative_title":["ISTA Thesis"],"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"day":"26","_id":"21360","article_processing_charge":"No","oa_version":"Published Version","citation":{"ama":"Riegler S. Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. 2026. doi:10.15479/AT-ISTA-21360","apa":"Riegler, S. (2026). Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21360","chicago":"Riegler, Stefan. “Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21360.","ista":"Riegler S. 2026. Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria.","mla":"Riegler, Stefan. Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21360.","short":"S. Riegler, Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species, Institute of Science and Technology Austria, 2026.","ieee":"S. Riegler, “Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species,” Institute of Science and Technology Austria, 2026."},"supervisor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","first_name":"Eva","last_name":"Benková","orcid":"0000-0002-8510-9739"}],"ddc":["570","575","583"],"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"publisher":"Institute of Science and Technology Austria","year":"2026","file":[{"access_level":"closed","creator":"sriegler","file_id":"21386","content_type":"application/x-zip-compressed","file_size":31430022,"checksum":"2f1f44e8536c2538f94a440217452c9f","date_updated":"2026-03-02T10:59:50Z","file_name":"2026_Riegler_Stefan_Thesis.zip","date_created":"2026-03-02T10:59:50Z","relation":"source_file"},{"file_size":11635090,"checksum":"2e8dc39640bc26ae5684c944c619719b","content_type":"application/pdf","file_name":"2026_Riegler_Stefan_Thesis.pdf","date_updated":"2026-03-02T10:59:49Z","relation":"main_file","embargo_to":"open_access","date_created":"2026-03-02T10:59:49Z","creator":"sriegler","access_level":"closed","file_id":"21387","embargo":"2027-02-27"}],"language":[{"iso":"eng"}],"tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode"},"doi":"10.15479/AT-ISTA-21360","page":"185","related_material":{"record":[{"id":"21363","status":"public","relation":"research_data"}]},"has_accepted_license":"1","month":"02","acknowledgement":"I would like to acknowledge the Austrian Academy of Sciences (ÖAW) and European\r\nResearch Executive Agency (REA) for funding my research (DOC ÖAW Fellowship\r\n26130, Horizon Europe BOLERO Project 101060393). ","type":"dissertation","degree_awarded":"PhD","OA_place":"repository","publication_identifier":{"issn":["2663-337X"]},"status":"public"},{"_id":"20833","type":"research_data","article_processing_charge":"No","oa_version":"Published Version","day":"8","department":[{"_id":"BeVi"}],"status":"public","publisher":"Institute of Science and Technology Austria","keyword":["Schizophora","sex chromosomes","sex-chromosome turnover","Diptera","genomic features","out-of-X movement."],"citation":{"ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Research Data for ‘Causes and consequences of sex-chromosome turnovers in Diptera.’” Institute of Science and Technology Austria, 2026.","mla":"Layana Franco, Lorena Alexandra, et al. Research Data for “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-20833.","short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, (2026).","ista":"Layana Franco LA, Toups MA, Vicoso B. 2026. Research Data for ‘Causes and consequences of sex-chromosome turnovers in Diptera’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-20833.","chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Research Data for ‘Causes and Consequences of Sex-Chromosome Turnovers in Diptera.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-20833.","apa":"Layana Franco, L. A., Toups, M. A., & Vicoso, B. (2026). Research Data for “Causes and consequences of sex-chromosome turnovers in Diptera.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20833","ama":"Layana Franco LA, Toups MA, Vicoso B. Research Data for “Causes and consequences of sex-chromosome turnovers in Diptera.” 2026. doi:10.15479/AT-ISTA-20833"},"doi":"10.15479/AT-ISTA-20833","corr_author":"1","has_accepted_license":"1","date_published":"2026-01-08T00:00:00Z","file":[{"access_level":"open_access","creator":"llayanaf","success":1,"file_id":"20834","file_name":"README.txt","date_updated":"2025-12-17T10:09:25Z","content_type":"text/plain","checksum":"0b79be6229f2ad9ac117ef00fc4f5c0e","file_size":1201,"date_created":"2025-12-17T10:09:25Z","relation":"main_file"},{"access_level":"open_access","creator":"llayanaf","success":1,"file_id":"20835","date_updated":"2025-12-17T10:10:11Z","file_name":"Supplementary_Datasets.zip","file_size":19052849,"checksum":"daf1c03149dd170b14e5c8e109ee3c77","content_type":"application/zip","date_created":"2025-12-17T10:10:11Z","relation":"main_file"},{"file_name":"Perl_scripts.zip","date_updated":"2025-12-17T10:12:05Z","checksum":"251e7aab01917c2ad2fbccf465492ea1","content_type":"application/zip","file_size":4575,"relation":"main_file","date_created":"2025-12-17T10:12:05Z","creator":"llayanaf","success":1,"access_level":"open_access","file_id":"20837"},{"access_level":"open_access","creator":"llayanaf","success":1,"file_id":"20959","file_name":"Supplementary_Tables.zip","date_updated":"2026-01-08T01:35:08Z","content_type":"application/zip","file_size":572362,"checksum":"3cabf143b8cd286eae48c598da2b03bd","date_created":"2026-01-08T01:35:08Z","relation":"main_file"}],"file_date_updated":"2026-01-08T01:35:08Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2026","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","oa":1,"abstract":[{"text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analysed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on the F element (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male-achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes.","lang":"eng"}],"date_updated":"2026-06-10T09:21:49Z","date_created":"2025-12-17T10:10:57Z","author":[{"orcid":"0000-0002-1253-6297","first_name":"Lorena Alexandra","last_name":"Layana Franco","full_name":"Layana Franco, Lorena Alexandra","id":"02814589-eb8f-11eb-b029-a70074f3f18f"},{"id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","full_name":"Toups, Melissa A","first_name":"Melissa A","last_name":"Toups","orcid":"0000-0002-9752-7380"},{"orcid":"0000-0002-4579-8306","first_name":"Beatriz","last_name":"Vicoso","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz"}],"title":"Research Data for 'Causes and consequences of sex-chromosome turnovers in Diptera'","month":"01"},{"day":"27","article_processing_charge":"No","oa_version":"Published Version","_id":"21363","type":"research_data","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"publisher":"Institute of Science and Technology Austria","status":"public","citation":{"chicago":"Riegler, Stefan. “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21363.","ama":"Riegler S. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species. 2026. doi:10.15479/AT-ISTA-21363","apa":"Riegler, S. (2026). Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21363","ieee":"S. Riegler, “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species.” Institute of Science and Technology Austria, 2026.","mla":"Riegler, Stefan. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21363.","short":"S. Riegler, (2026).","ista":"Riegler S. 2026. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21363."},"ddc":["575"],"date_published":"2026-02-27T00:00:00Z","has_accepted_license":"1","corr_author":"1","related_material":{"record":[{"relation":"used_in_publication","id":"21360","status":"public"}]},"doi":"10.15479/AT-ISTA-21363","year":"2026","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode"},"file":[{"file_size":63749444,"content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","checksum":"de9145fa166a28c588b5184a2d3d4fee","date_updated":"2026-02-27T09:11:33Z","file_name":"SupplementaryTables.xlsx","embargo_to":"open_access","date_created":"2026-02-27T09:11:33Z","relation":"main_file","access_level":"closed","creator":"sriegler","embargo":"2027-02-27","file_id":"21364"},{"relation":"main_file","embargo_to":"open_access","date_created":"2026-02-27T09:13:11Z","content_type":"text/plain","file_size":124,"checksum":"ce1f163551c96cee45943a8ea29720b6","date_updated":"2026-02-27T09:13:11Z","file_name":"ReadMe.txt","file_id":"21365","embargo":"2027-02-27","creator":"sriegler","access_level":"closed"}],"file_date_updated":"2026-02-27T09:13:11Z","date_updated":"2026-06-10T09:39:13Z","contributor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","contributor_type":"supervisor","orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková"}],"abstract":[{"text":"The data contains information on coffee differential gene expression as well as co-expression and trait correlations in two separate experiments. First, contrasting nitrogen supply, second, intra- and interspecific grafting.","lang":"eng"}],"month":"02","title":"Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species","author":[{"first_name":"Stefan","last_name":"Riegler","orcid":"0000-0003-3413-1343","full_name":"Riegler, Stefan","id":"FF6018E0-D806-11E9-8E43-0B14E6697425"}],"date_created":"2026-02-27T09:18:41Z"},{"acknowledged_ssus":[{"_id":"ScienComp"}],"publisher":"Institute of Science and Technology Austria","supervisor":[{"orcid":"0000-0001-6005-1561","first_name":"Edouard B","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B"}],"citation":{"chicago":"Dunajova, Zuzana. “Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21423.","apa":"Dunajova, Z. (2026). Geometry-driven self-organization of migrating cells and chiral filaments. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21423","ama":"Dunajova Z. Geometry-driven self-organization of migrating cells and chiral filaments. 2026. doi:10.15479/AT-ISTA-21423","ieee":"Z. Dunajova, “Geometry-driven self-organization of migrating cells and chiral filaments,” Institute of Science and Technology Austria, 2026.","short":"Z. Dunajova, Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments, Institute of Science and Technology Austria, 2026.","mla":"Dunajova, Zuzana. Geometry-Driven Self-Organization of Migrating Cells and Chiral Filaments. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21423.","ista":"Dunajova Z. 2026. Geometry-driven self-organization of migrating cells and chiral filaments. Institute of Science and Technology Austria."},"ddc":["539","570"],"day":"11","article_processing_charge":"No","oa_version":"Published Version","_id":"21423","alternative_title":["ISTA Thesis"],"department":[{"_id":"GradSch"},{"_id":"EdHa"}],"date_updated":"2026-06-10T09:41:11Z","project":[{"grant_number":"26360","name":"Motile active matter models of migrating cells and chiral filaments","_id":"34d75525-11ca-11ed-8bc3-89b6307fee9d"}],"title":"Geometry-driven self-organization of migrating cells and chiral filaments","author":[{"full_name":"Dunajova, Zuzana","id":"4B39F286-F248-11E8-B48F-1D18A9856A87","last_name":"Dunajova","first_name":"Zuzana"}],"date_created":"2026-03-11T08:30:49Z","date_published":"2026-03-11T00:00:00Z","corr_author":"1","publication_status":"published","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","file_date_updated":"2026-03-13T11:19:21Z","publication_identifier":{"isbn":["978-3-99078-076-3"],"issn":["2663-337X"]},"status":"public","OA_place":"repository","degree_awarded":"PhD","type":"dissertation","acknowledgement":"Finally, I gratefully acknowledge funding from the DOC Fellowship of the Austrian Academy\r\nof Sciences (OeAW): grant agreement 26360.","month":"03","has_accepted_license":"1","related_material":{"record":[{"status":"public","id":"13314","relation":"part_of_dissertation"},{"id":"13116","status":"public","relation":"research_data"},{"id":"21427","status":"public","relation":"part_of_dissertation"},{"status":"public","id":"21439","relation":"research_data"}]},"page":"110","doi":"10.15479/AT-ISTA-21423","year":"2026","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"file":[{"relation":"main_file","embargo_to":"open_access","date_created":"2026-03-12T20:38:52Z","checksum":"47ce6a48a0c63f28eca6e64c9ffd2c84","content_type":"application/pdf","file_size":14662770,"date_updated":"2026-03-12T20:38:52Z","file_name":"2026_Dunajova_Zuzana_Thesis_pdfA.pdf","file_id":"21446","embargo":"2026-09-11","creator":"zdunajov","access_level":"closed"},{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","checksum":"5dec5afdffd47c2b0b162d0fe1bed925","file_size":32961408,"date_updated":"2026-03-13T11:19:21Z","file_name":"Thesis-Dunajova_source_file.docx","date_created":"2026-03-12T20:40:18Z","relation":"source_file","access_level":"closed","creator":"zdunajov","file_id":"21447"}],"language":[{"iso":"eng"}]},{"OA_type":"gold","date_published":"2026-05-12T00:00:00Z","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"epub_ahead","publication":"Nature Communications","date_updated":"2026-06-10T09:45:53Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-026-72577-4"}],"abstract":[{"text":"Magneto-optic Kerr effect (MOKE) is a powerful probe of broken time-reversal symmetry (T), typically used to study ferromagnets. While MOKE has been observed in some antiferromagnets (AFMs) with vanishing magnetization, it is often associated with structures whose symmetry is lower than basic collinear, bipartite order. In contrast, theory predicts a mechanism for MOKE intrinsic to all AFMs of A-type, i.e. layered AFMs in which ferromagnetic layers are antiferromagnetically aligned. Here we report the experimental confirmation of this mechanism in a bulk AFM. We achieve this by measuring the imaginary component of MOKE as a function of photon energy in MnBi2Te4, an A-type AFM where T is preserved in combination with a translation, and comparing the experimental results with model calculations. Our model suggests that observable MOKE should be expected in all collinear A-type AFMs with out-of-plane spin order, thus enabling optical detection of AFM domains and expanding the scope of MOKE to few-layer AFMs.","lang":"eng"}],"date_created":"2026-05-12T21:31:27Z","title":"Magneto-optical Kerr effect in an A-type antiferromagnet","author":[{"id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3","full_name":"Sunko, Veronika","orcid":"0000-0003-2724-3523","first_name":"Veronika","last_name":"Sunko"},{"full_name":"Ahsanullah, Salman","first_name":"Salman","last_name":"Ahsanullah"},{"first_name":"Vivek","last_name":"Jain","full_name":"Jain, Vivek"},{"first_name":"Sophie","last_name":"Weber","full_name":"Weber, Sophie"},{"first_name":"Sivaloganathan","last_name":"Kumaran","full_name":"Kumaran, Sivaloganathan"},{"full_name":"Yan, Jiaqiang","last_name":"Yan","first_name":"Jiaqiang"},{"full_name":"Orenstein, Joseph","first_name":"Joseph","last_name":"Orenstein"},{"first_name":"Dmitry","last_name":"Ovchinnikov","full_name":"Ovchinnikov, Dmitry"}],"day":"12","_id":"21872","oa_version":"Published Version","article_processing_charge":"Yes","scopus_import":"1","article_type":"original","department":[{"_id":"VeSu"}],"publisher":"Springer Nature","quality_controlled":"1","citation":{"mla":"Sunko, Veronika, et al. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” Nature Communications, Springer Nature, 2026, doi:10.1038/s41467-026-72577-4.","short":"V. Sunko, S. Ahsanullah, V. Jain, S. Weber, S. Kumaran, J. Yan, J. Orenstein, D. Ovchinnikov, Nature Communications (2026).","ieee":"V. Sunko et al., “Magneto-optical Kerr effect in an A-type antiferromagnet,” Nature Communications. Springer Nature, 2026.","ista":"Sunko V, Ahsanullah S, Jain V, Weber S, Kumaran S, Yan J, Orenstein J, Ovchinnikov D. 2026. Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications.","chicago":"Sunko, Veronika, Salman Ahsanullah, Vivek Jain, Sophie Weber, Sivaloganathan Kumaran, Jiaqiang Yan, Joseph Orenstein, and Dmitry Ovchinnikov. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” Nature Communications. Springer Nature, 2026. https://doi.org/10.1038/s41467-026-72577-4.","apa":"Sunko, V., Ahsanullah, S., Jain, V., Weber, S., Kumaran, S., Yan, J., … Ovchinnikov, D. (2026). Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-026-72577-4","ama":"Sunko V, Ahsanullah S, Jain V, et al. Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. 2026. doi:10.1038/s41467-026-72577-4"},"ddc":["530"],"doi":"10.1038/s41467-026-72577-4","has_accepted_license":"1","PlanS_conform":"1","related_material":{"record":[{"relation":"research_data","id":"21422","status":"public"}]},"year":"2026","oa":1,"language":[{"iso":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"DOAJ_listed":"1","month":"05","type":"journal_article","acknowledgement":"We thank Christine Kuntscher for providing optical conductivity and reflectance data published in ref. 33, and Nicola Spaldin, Joel Moore and Bevin Huang for useful discussions. V.S. and J.O. received support from the Gordon and Betty Moore Foundation’s EPiQS Initiative through Grant GBMF4537 awarded to J.O. at UC Berkeley. Experimental and theoretical work at LBNL and UC Berkeley was funded by the Quantum Materials (KC2202) program under the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract No. DE-AC02-05CH11231. Work at the University of Kansas was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, EPSCoR, and Materials Sciences and Engineering Division under Award No. DE-SC0025319. Parts of device fabrication were performed in the KU Nanofabrication Facility, which is supported by the National Institutes of Health NIGMS P30GM145499. Work at ORNL was supported by the U. S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Sciences and Engineering Division. For the DFT calculations we used resources provided by the Swedish National Infrastructure for Computing (SNIC) at C3SE. We acknowledge support from the US National Science Foundation (NSF) Grant Number 2201516 under the Accelnet program of Office of International Science and Engineering (OISE). This publication is funded in part by a QuantEmX grant from ICAM and the Gordon and Betty Moore Foundation through Grant GBMF9616 to S. K.","publication_identifier":{"eissn":["2041-1723"]},"status":"public","OA_place":"publisher"},{"project":[{"grant_number":"665385","name":"International IST Doctoral Program","call_identifier":"H2020","_id":"2564DBCA-B435-11E9-9278-68D0E5697425"},{"_id":"8f060199-16d5-11f0-9cad-f3253b266c46","grant_number":"PAT 5044023","name":"Keratins in epithelial tissue spreading"},{"grant_number":"W1250-B20","name":"Nano-Analytics of Cellular Systems","call_identifier":"FWF","_id":"252C3B08-B435-11E9-9278-68D0E5697425"}],"month":"3","date_created":"2026-02-04T16:38:02Z","title":"Data associated with Keratins coordinate tissue spreading ","author":[{"id":"2C0B105C-F248-11E8-B48F-1D18A9856A87","full_name":"Naik, Suyash","orcid":"0000-0001-8421-5508","first_name":"Suyash","last_name":"Naik"}],"date_updated":"2026-06-10T09:44:10Z","contributor":[{"contributor_type":"researcher","last_name":"Keta","first_name":"Yann-Edwin"},{"contributor_type":"supervisor","last_name":"Henkes","first_name":"Silke "},{"orcid":"0000-0002-0912-4566","contributor_type":"supervisor","last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87"},{"contributor_type":"supervisor","orcid":"0000-0001-6005-1561","first_name":"Edouard B","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"}],"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","year":"2026","oa":1,"file_date_updated":"2026-03-24T07:21:43Z","file":[{"title":"Cell git repository","date_created":"2026-03-16T11:51:10Z","relation":"main_file","file_size":725916,"content_type":"application/zip","checksum":"5d1fda7e410f24c311fcf6bcf725698f","file_name":"cells-main.zip","date_updated":"2026-03-16T11:51:10Z","description":"Python3 library written in C++20 to integrate vertex models. Please read the readme at https://github.com/yketa/cells/blob/main/README.md for detailed instructions for installation and usage of the code in this repository. 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Naik, “Data associated with Keratins coordinate tissue spreading .” Institute of Science and Technology Austria, 2026.","mla":"Naik, Suyash. Data Associated with Keratins Coordinate Tissue Spreading . Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21137.","short":"S. Naik, (2026).","ista":"Naik S. 2026. Data associated with Keratins coordinate tissue spreading , Institute of Science and Technology Austria, 10.15479/AT-ISTA-21137.","chicago":"Naik, Suyash. “Data Associated with Keratins Coordinate Tissue Spreading .” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21137.","apa":"Naik, S. (2026). Data associated with Keratins coordinate tissue spreading . Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21137","ama":"Naik S. 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This work was supported by the Austrian Science Fund (FWF) under projects PAT5044023 and W1250 awarded to C.-P.H.","day":"24","type":"research_data","_id":"21137","article_processing_charge":"No","oa_version":"Published Version"},{"OA_place":"repository","status":"public","type":"research_data","month":"03","contributor":[{"id":"4323B49C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1671-393X","contributor_type":"researcher","first_name":"Saren","last_name":"Tasciyan"},{"id":"40136C2A-F248-11E8-B48F-1D18A9856A87","first_name":"Philipp","last_name":"Radler","contributor_type":"researcher","orcid":"0000-0001-9198-2182 "}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"file":[{"content_type":"application/zip","file_size":154465214,"checksum":"47809a9a31b748b16e21e92d11ddc87f","file_name":"Supplementary_movies_Thesis_Dunajova.zip","date_updated":"2026-03-11T20:41:28Z","relation":"main_file","date_created":"2026-03-11T20:41:28Z","success":1,"creator":"zdunajov","access_level":"open_access","file_id":"21440"},{"access_level":"open_access","creator":"zdunajov","success":1,"file_id":"21441","date_updated":"2026-03-11T20:52:39Z","file_name":"readme.txt","file_size":2289,"content_type":"text/plain","checksum":"a64a174bc6abf0a5e77631e4fd121f1f","date_created":"2026-03-11T20:52:39Z","relation":"main_file"}],"oa":1,"year":"2026","has_accepted_license":"1","related_material":{"record":[{"status":"public","id":"13314","relation":"used_in_publication"},{"relation":"used_in_publication","id":"21427","status":"public"},{"status":"public","id":"21423","relation":"used_in_publication"}]},"doi":"10.15479/AT-ISTA-21439","ddc":["570"],"citation":{"ama":"Dunajova Z. 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FR and PY gratefully acknowledge Matthias Weiss (Experimental Physics I, University of Bayreuth, Germany) for granting access to cell culture and laboratories, as well as funding consumables and the fruitful discussion that contributed to this work. 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We present a computational framework that uses topological data analysis to characterise and compare single-cell morphologies from fluorescence microscopy. Each cell is represented by its contour together with the position of its nucleus, from which we construct a filtration based on a radial distance function and derive a persistence diagram encoding the shape’s topological evolution. The similarity between two cells is quantified using the 2-Wasserstein distance between their diagrams, yielding a shape distance we call the PH distance. We apply this method to two representative experimental systems—primary human mesenchymal stem cells (hMSCs) and HeLa cells—and show that PH distances enable the detection of outliers in those systems, the identification of sub-populations, and the quantification of shape heterogeneity. We benchmark PH against three established contour-based distances (aspect ratio, Fourier descriptors, and elastic shape analysis) and show that PH offers better separation between cell types and greater robustness when clustering heterogeneous populations. Together, these results demonstrate that persistent-homology-based signatures provide a principled and sensitive approach for analysing cell morphology in settings where traditional geometric or image-based descriptors are insufficient."}]},{"OA_place":"publisher","volume":5,"status":"public","publication_identifier":{"issn":["2730-9657"]},"acknowledgement":"The author would like to thank Kate Turner, Chris Williams, Jonathan Spreer, Stephan Tillmann, Vanessa Robins, Vigleik Angeltveit, Martin Helmer, and James Morgan for very helpful discussions; and thanks Sara Kališnik Hintz and Paul Bendich for comments on an earlier version. Additonally, the author would like to thank both reviewers for their very insightful and helpful comments, without which the paper would be infinitely less coherent than it currently is. Open access funding provided by Institute of Science and Technology (IST Austria). The work in this paper was supported by an Australian Federal Government Grant, 2019-2022, Stratified Space Learning.","type":"journal_article","month":"02","arxiv":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"file_id":"21347","creator":"dernst","success":1,"access_level":"open_access","relation":"main_file","date_created":"2026-02-23T10:18:52Z","file_name":"2026_LaMatematica_Bleile.pdf","date_updated":"2026-02-23T10:18:52Z","checksum":"6cae2efb47b025af22a8539c606a4e09","file_size":15051582,"content_type":"application/pdf"}],"language":[{"iso":"eng"}],"oa":1,"year":"2026","PlanS_conform":"1","has_accepted_license":"1","doi":"10.1007/s44007-025-00183-9","ddc":["510"],"citation":{"apa":"Bokor Bleile, Y. (2026). Towards stratified space learning: 2-complexes. La Matematica. 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In the first part, we present a hybrid symbolic-numeric algorithm for certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating linear matrix inequalities (LMIs) into a structured polynomial system via facial reduction and incidence varieties, we guarantee the existence of an isolated exact solution. This algebraic reduction enables the certification of maximum-rank numerical approximations using methods from algebraic geometry.\r\n\r\nIn the second part, we address the severe ill-conditioning and loss of quadratic convergence that plague standard path-tracking methods near isolated singular roots. To overcome this, we propose tracking algorithms that achieve superlinear convergence without the computational bloat characteristic of classical deflation techniques. By modeling the solution path as a generalized fractional Puiseux series, our approach combines an explicitly derived algebraic predictor with a localized hyperplane desingularization phase during the corrector step. Furthermore, we introduce a continuous path-limit method and an extension of the geometric sequence rule to directly extract exact fractional exponents. This bypasses traditional heuristic trial-and-error methods and explicitly accommodates sparse series expansions. 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How epistasis and purifying selection shape genetic diversity. Institute of Science and Technology Austria.","mla":"Khudiakova, Kseniia. How Epistasis and Purifying Selection Shape Genetic Diversity. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21918.","short":"K. Khudiakova, How Epistasis and Purifying Selection Shape Genetic Diversity, Institute of Science and Technology Austria, 2026.","ieee":"K. Khudiakova, “How epistasis and purifying selection shape genetic diversity,” Institute of Science and Technology Austria, 2026.","apa":"Khudiakova, K. (2026). How epistasis and purifying selection shape genetic diversity. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21918","ama":"Khudiakova K. How epistasis and purifying selection shape genetic diversity. 2026. doi:10.15479/AT-ISTA-21918","chicago":"Khudiakova, Kseniia. “How Epistasis and Purifying Selection Shape Genetic Diversity.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21918."},"ddc":["576"],"page":"89","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"11447"},{"id":"12513","status":"deleted","relation":"part_of_dissertation"},{"id":"21967","status":"public","relation":"part_of_dissertation"},{"status":"public","id":"21968","relation":"part_of_dissertation"}]},"has_accepted_license":"1","doi":"10.15479/AT-ISTA-21918","year":"2026","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"language":[{"iso":"eng"}],"file":[{"file_id":"21965","access_level":"closed","creator":"kkhudiak","date_created":"2026-06-09T08:34:38Z","relation":"source_file","file_name":"thesis.zip","date_updated":"2026-06-09T08:40:48Z","file_size":20549813,"content_type":"application/x-zip-compressed","checksum":"0cff64ae74f0f9f2d7011700c82f700a"},{"embargo":"2027-06-10","file_id":"21969","access_level":"closed","creator":"kkhudiak","embargo_to":"open_access","date_created":"2026-06-09T12:28:51Z","relation":"main_file","checksum":"547ae42de37cc86894af283f1664dbc8","content_type":"application/pdf","file_size":9387029,"date_updated":"2026-06-11T12:14:53Z","file_name":"2026_Khudiakova_Ksenia_Thesis.pdf"}],"month":"06","degree_awarded":"PhD","type":"dissertation","acknowledgement":"At different stages of my PhD, my work was supported by several grants: the\r\nDOC fellowship of the Austrian Academy of Sciences (26293, awarded to me),\r\nthe FWF-SFB grant (PT1032F06504 n. F65, awarded to Jan Maas), and the ERC\r\ngrant (PR1032ERC01 n. 716117, awarded to Jan Maas). I also appreciate the help\r\nfrom the Scientific Computing unit for their advice on the cluster usage.","publication_identifier":{"issn":["2663-337X"]},"ec_funded":1,"status":"public","OA_place":"publisher"},{"day":"23","oa_version":"Preprint","article_processing_charge":"No","type":"preprint","_id":"21968","acknowledgement":"This work was funded by grants from the Swedish Research Council (2023-03730 to G.A.) and the DOC fellowship from the Austrian Academy of Science (26293 to K.K.).","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"status":"public","citation":{"chicago":"Khudiakova, Kseniia, Nicholas H Barton, and Goran Arnqvist. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” BioRxiv, n.d. https://doi.org/10.1101/2025.04.09.647826.","apa":"Khudiakova, K., Barton, N. H., & Arnqvist, G. (n.d.). Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv. https://doi.org/10.1101/2025.04.09.647826","ama":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv. doi:10.1101/2025.04.09.647826","ieee":"K. Khudiakova, N. H. Barton, and G. Arnqvist, “Sign epistasis extends the effects of balancing selection on genetic diversity,” bioRxiv. .","short":"K. Khudiakova, N.H. Barton, G. Arnqvist, BioRxiv (n.d.).","mla":"Khudiakova, Kseniia, et al. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” BioRxiv, doi:10.1101/2025.04.09.647826.","ista":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv, 10.1101/2025.04.09.647826."},"OA_place":"repository","date_published":"2026-04-23T00:00:00Z","OA_type":"green","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"21918"}]},"corr_author":"1","doi":"10.1101/2025.04.09.647826","oa":1,"publication_status":"draft","year":"2026","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"language":[{"iso":"eng"}],"publication":"bioRxiv","main_file_link":[{"url":"https://doi.org/10.1101/2025.04.09.647826","open_access":"1"}],"date_updated":"2026-06-12T12:43:34Z","abstract":[{"lang":"eng","text":"Balancing selection, a form of selection that maintains genetic diversity, is difficult to detect, and the importance of balancing selection for the maintenance of genetic variation may be larger than often assumed. We model the possibility that the diversity-promoting effects of balancing selection extend to other loci that show sign epistasis with a locus under balancing selection. Rather than focusing on overdominance, as was done in previous efforts, we explore the effects of negative frequency dependence and show that this has important effects on the conditions under which the diversity-promoting effect of epistasis can occur in diploids. Our results show that not only recombination rate but also the dominance of sign epistasis are key parameters that determine the maintenance of polymorphism beyond the locus under direct balancing selection. We suggest that the effect we explore may play a significant role, especially when balancing selection acts on major effect loci."}],"project":[{"name":"The impact of deleterious mutations on small populations","grant_number":"26293","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8"}],"month":"04","title":"Sign epistasis extends the effects of balancing selection on genetic diversity","author":[{"full_name":"Khudiakova, Kseniia","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","last_name":"Khudiakova","first_name":"Kseniia","orcid":"0000-0002-6246-1465"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","last_name":"Barton"},{"full_name":"Arnqvist, Goran","first_name":"Goran","last_name":"Arnqvist"}],"date_created":"2026-06-09T12:26:11Z"},{"type":"preprint","acknowledgement":"We thank A. Heger (IST Austria Preclinical Facility), A. Sommer (VBCF GmbH, NGS Unit), and A.\r\nNicolas (IST Austria Lab Support Facility / Mass Spectrometry Facility) for technical support; K. Ferencak,\r\nI. Aykara, P. Hirschfeld, E. Fisher, S. Laukoter, L. Andersen for initial experiments and/or assistance; and\r\nall members of the Hippenmeyer lab for discussion. This research was supported by the Scientific Service\r\nUnits (SSU) of IST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). R.B. received support from FWF Meitner-Programm (M 2416). This\r\nwork was also supported by IST Austria institutional funds; the People Programme (Marie Curie Actions)\r\nof the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement\r\nNo 618444 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation programme (grant agreement No 725780 LinPro) to S.H.","status":"public","ec_funded":1,"OA_place":"repository","doi":"10.64898/2026.05.01.722172","has_accepted_license":"1","language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"year":"2026","oa":1,"month":"05","_id":"21962","oa_version":"Preprint","article_processing_charge":"No","day":"05","department":[{"_id":"SiHi"}],"acknowledged_ssus":[{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"Bio"}],"ddc":["570"],"citation":{"ista":"Villalba Requena A, Beattie RJ, Pauler F, Streicher C, Miranda O, Krausgruber T, Senekowitsch M, Farlik M, Bock C, Rülicke T, Hippenmeyer S. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv, 10.64898/2026.05.01.722172.","short":"A. Villalba Requena, R.J. Beattie, F. Pauler, C. Streicher, O. Miranda, T. Krausgruber, M. Senekowitsch, M. Farlik, C. Bock, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","mla":"Villalba Requena, Ana, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” BioRxiv, doi:10.64898/2026.05.01.722172.","ieee":"A. Villalba Requena et al., “Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner,” bioRxiv. .","ama":"Villalba Requena A, Beattie RJ, Pauler F, et al. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv. doi:10.64898/2026.05.01.722172","apa":"Villalba Requena, A., Beattie, R. J., Pauler, F., Streicher, C., Miranda, O., Krausgruber, T., … Hippenmeyer, S. (n.d.). Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv. https://doi.org/10.64898/2026.05.01.722172","chicago":"Villalba Requena, Ana, Robert J Beattie, Florian Pauler, Carmen Streicher, Osvaldo Miranda, Thomas Krausgruber, Martin Senekowitsch, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” BioRxiv, n.d. https://doi.org/10.64898/2026.05.01.722172."},"OA_type":"green","date_published":"2026-05-05T00:00:00Z","publication":"bioRxiv","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"submitted","abstract":[{"lang":"eng","text":"The generation of faithful cell-type diversity and correct projection neuron numbers is essential for cerebral cortex development. Corticogenesis is however susceptible to genetic interference of critical signaling pathways, including mutations in Mtor/Rptor that lead to microcephaly. How the loss of Rptor/mTORC1 function affects cortical developmental programs, at single cell level, is still unknown. Here, we utilized Mosaic Analysis with Double Markers (MADM) technology to probe Rptor gene function upon sparse single cell- or global tissue-wide ablation. We found that tissue-wide effects drive the etiology of cortical microcephaly upon loss of Rptor, rather than deficits in projection neuron genesis. Conversely, Rptor function is cell-autonomously required for postnatal projection neuron survival in a highly cell-type-specific manner. Collectively, our results suggest that the fine balance of precise cell-type-specific cell-autonomous Rptor/mTORC1 function in concert with non-cell-autonomous tissue-wide effects is essential for the development of a properly-sized cerebral cortex with accurate projection neuron diversity."}],"date_updated":"2026-06-16T08:45:25Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.05.01.722172"}],"date_created":"2026-06-09T08:08:18Z","title":"Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner","author":[{"id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","full_name":"Villalba Requena, Ana","last_name":"Villalba Requena","first_name":"Ana","orcid":"0000-0002-5615-5277"},{"id":"2E26DF60-F248-11E8-B48F-1D18A9856A87","full_name":"Beattie, Robert J","first_name":"Robert J","last_name":"Beattie","orcid":"0000-0002-8483-8753"},{"id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian","orcid":"0000-0002-7462-0048","first_name":"Florian","last_name":"Pauler"},{"id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","full_name":"Streicher, Carmen","last_name":"Streicher","first_name":"Carmen"},{"first_name":"Osvaldo","last_name":"Miranda","orcid":"0000-0001-6618-6889","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425"},{"full_name":"Krausgruber, Thomas","last_name":"Krausgruber","first_name":"Thomas"},{"last_name":"Senekowitsch","first_name":"Martin","full_name":"Senekowitsch, Martin"},{"full_name":"Farlik, Matthias","last_name":"Farlik","first_name":"Matthias"},{"last_name":"Bock","first_name":"Christoph","full_name":"Bock, Christoph"},{"full_name":"Rülicke, Thomas","first_name":"Thomas","last_name":"Rülicke"},{"full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","first_name":"Simon"}],"project":[{"_id":"264E56E2-B435-11E9-9278-68D0E5697425","grant_number":"M02416","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex","call_identifier":"FWF"},{"call_identifier":"FP7","grant_number":"618444","name":"Molecular Mechanisms of Cerebral Cortex Development","_id":"25D61E48-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","grant_number":"725780","_id":"260018B0-B435-11E9-9278-68D0E5697425"}]},{"status":"public","publication_identifier":{"issn":["0896-6273"],"eissn":[" 1097-4199"]},"keyword":["hunger","hypothalamus","AGRP neurons","neuroscience","metabolism","homeostasis","feeding","food intake","energy balance","appetite"],"OA_place":"repository","type":"journal_article","acknowledgement":"We thank all members of the B.B.L. laboratory for helpful discussions. We\r\nthank the BADERC and BNORC transgenic cores (NIH P30DK057521 and\r\nP30DK046200) for performing embryo injections to generate knockin mouse\r\nlines. We also thank the BIDMC Energy Balance Core (supported by NIH\r\nS10OD028635 and the Boston Area Diabetes Endocrinology Research Centers, P30DK135043), where Marissa Cortopassi performed indirect calorimetry experiments and Alexander Banks assisted with data analysis and interpretation. Confocal imaging was performed at BIDMC’s Confocal Imaging\r\nCore. We thank Chen Wu for assistance in designing knockin mouse lines.\r\nThis work was supported by the NIH (R01DK134427, R01DK096010, and\r\nR01DK075632 to B.B.L.). Authors were supported by an EMBO Long-Term\r\nFellowship (770-2018, S.J.W.), a T32 Postdoctoral Training Fellowship\r\n(5T32DK007516, E.D.L.), the Charles A. King Trust Postdoctoral Research\r\nFellowship program (A.M.D.), and a K99 Career Development Award\r\n(K99HL144923, J.M.R.).","month":"06","doi":"10.1016/j.neuron.2026.05.010","language":[{"iso":"eng"}],"oa":1,"year":"2026","publisher":"Elsevier","quality_controlled":"1","citation":{"apa":"Walker, S. J., Lowenstein, E. D., Douglass, A. M., Thomas, C. M. P., Madara, J. C., Kucukdereli, H., … Lowell, B. B. (n.d.). A hypothalamic circuit for anticipating future changes in energy balance. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2026.05.010","ama":"Walker SJ, Lowenstein ED, Douglass AM, et al. A hypothalamic circuit for anticipating future changes in energy balance. Neuron. doi:10.1016/j.neuron.2026.05.010","chicago":"Walker, Samuel J., Elijah D. Lowenstein, Amelia M. Douglass, Callum M.P. Thomas, Joseph C. Madara, Hakan Kucukdereli, Eunice A. Barbosa-Meillon, Jenkang Tao, Jon M. Resch, and Bradford B. Lowell. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” Neuron. Elsevier, n.d. https://doi.org/10.1016/j.neuron.2026.05.010.","ista":"Walker SJ, Lowenstein ED, Douglass AM, Thomas CMP, Madara JC, Kucukdereli H, Barbosa-Meillon EA, Tao J, Resch JM, Lowell BB. A hypothalamic circuit for anticipating future changes in energy balance. Neuron.","mla":"Walker, Samuel J., et al. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” Neuron, Elsevier, doi:10.1016/j.neuron.2026.05.010.","short":"S.J. Walker, E.D. Lowenstein, A.M. Douglass, C.M.P. Thomas, J.C. Madara, H. Kucukdereli, E.A. Barbosa-Meillon, J. Tao, J.M. Resch, B.B. Lowell, Neuron (n.d.).","ieee":"S. J. Walker et al., “A hypothalamic circuit for anticipating future changes in energy balance,” Neuron. Elsevier."},"article_processing_charge":"No","oa_version":"Preprint","_id":"21955","day":"03","department":[{"_id":"AmDo"}],"scopus_import":"1","article_type":"original","abstract":[{"text":"AgRP neurons cause hunger, the drive to seek and consume food. Their activation by fasting is key for survival and is thought to be triggered by feedback when energy stores are low. However, we know that environmental cues can also regulate AgRP neurons since cues that predict future food intake rapidly inhibit AgRP neurons, but is the converse true: can the prediction of future fasting rapidly activate AgRP neurons? Here, we show in mice that such rapid fasting activation of AgRP neurons does occur. This rapid activation is driven by excitatory input from paraventricular hypothalamic (PVH) neurons expressing Sim2, which are bidirectionally sensitive to predictions of future energy state. Thus, cognitively processed contextual information conveyed by PVHSim2 neurons strongly activates AgRP neurons. Lastly, chronic silencing of PVHSim2 neurons causes persistent hypophagia. This PVHSim2-to-AgRP-neuron circuit, by anticipating and preventing negative energy balance, provides an important new dimension of hunger regulation.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.09.27.678865"}],"date_updated":"2026-06-16T08:35:11Z","author":[{"first_name":"Samuel J.","last_name":"Walker","full_name":"Walker, Samuel J."},{"full_name":"Lowenstein, Elijah D.","last_name":"Lowenstein","first_name":"Elijah D."},{"full_name":"Douglass, Amelia May Barnett","id":"de5f6fda-80fb-11ef-996f-a8c4ecd8e289","last_name":"Douglass","first_name":"Amelia May Barnett","orcid":"0000-0001-5398-6473"},{"full_name":"Thomas, Callum M.P.","last_name":"Thomas","first_name":"Callum M.P."},{"first_name":"Joseph C.","last_name":"Madara","full_name":"Madara, Joseph C."},{"last_name":"Kucukdereli","first_name":"Hakan","full_name":"Kucukdereli, Hakan"},{"last_name":"Barbosa-Meillon","first_name":"Eunice A.","full_name":"Barbosa-Meillon, Eunice A."},{"first_name":"Jenkang","last_name":"Tao","full_name":"Tao, Jenkang"},{"last_name":"Resch","first_name":"Jon M.","full_name":"Resch, Jon M."},{"full_name":"Lowell, Bradford B.","last_name":"Lowell","first_name":"Bradford B."}],"title":"A hypothalamic circuit for anticipating future changes in energy balance","date_created":"2026-06-08T09:24:25Z","external_id":{"pmid":["42235510"]},"date_published":"2026-06-03T00:00:00Z","OA_type":"green","publication":"Neuron","publication_status":"inpress","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"date_published":"2026-06-16T00:00:00Z","doi":"10.15479/AT-ISTA-21960","has_accepted_license":"1","corr_author":"1","year":"2026","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","oa":1,"file":[{"file_id":"22010","success":1,"creator":"akerschb","access_level":"open_access","relation":"main_file","date_created":"2026-06-15T22:01:57Z","content_type":"text/plain","checksum":"133269a105e996c6c44fdd56128259c7","file_size":1940,"date_updated":"2026-06-15T22:01:57Z","file_name":"README.txt"},{"relation":"main_file","date_created":"2026-06-15T22:02:07Z","file_name":"Soliton_Data.zip","date_updated":"2026-06-15T22:02:07Z","checksum":"759f9649c3919f4c4ad37a1d104ea32a","content_type":"application/zip","file_size":13259747,"file_id":"22011","creator":"akerschb","success":1,"access_level":"open_access"}],"file_date_updated":"2026-06-15T22:02:07Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"date_updated":"2026-06-16T08:00:38Z","contributor":[{"id":"ade85a9c-3200-11ee-973b-91c1eb240410","contributor_type":"contact_person","orcid":"0009-0002-2370-8661","first_name":"Aron","last_name":"Kerschbaumer"},{"orcid":"0000-0002-2399-5827","contributor_type":"supervisor","first_name":"Maksym","last_name":"Serbyn","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"},{"id":"6c292945-a610-11ed-9eec-c3be1ad62a80","last_name":"Desaules","first_name":"Jean-Yves Marc","contributor_type":"researcher","orcid":"0000-0002-3749-6375"},{"contributor_type":"researcher","last_name":"Ljubotina","first_name":"Marko"}],"abstract":[{"lang":"eng","text":"Solitons - localized wave packets that travel without spreading - play a central role in understanding transport and properties of nonlinear systems. In quantum many-body systems, however, such robust excitations are typically destroyed by thermalization. Here, we theoretically demonstrate the existence of solitonic excitations in high-energy states of Rydberg atom chains in the regime of strong nearest-neighbor Rydberg blockade. \r\nThese localized wave packets propagate directionally atop a special class of reviving initial states related to quantum many-body scars and are capable of carrying energy. Exhibiting long coherence times, these states constitute a form of non-ergodic quantum dynamics and can be efficiently implemented on Rydberg atom simulators. In this work, in addition to a phenomenological description of solitons, we identify their counterpart in a classical nonlinear dynamical system, demonstrate their potential use in quantum information transfer, and conjecture their relevance for anomalous energy transport reported in numerical studies of Rydberg atom arrays."}],"project":[{"call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"month":"06","date_created":"2026-06-09T07:17:50Z","title":"Research Data: \"Quasi-solitons in Rydberg atom chains\"","author":[{"full_name":"Kerschbaumer, Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410","last_name":"Kerschbaumer","first_name":"Aron","orcid":"0009-0002-2370-8661"}],"day":"16","type":"research_data","_id":"21960","oa_version":"Published Version","article_processing_charge":"No","department":[{"_id":"GradSch"},{"_id":"MaSe"}],"status":"public","publisher":"Institute of Science and Technology Austria","ec_funded":1,"OA_place":"repository","citation":{"ieee":"A. 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