[{"external_id":{"pmid":["41851325"]},"author":[{"id":"0C5FDA4A-9CF6-11E9-8939-FF05E6697425","full_name":"Grosjean, Galien M","orcid":"0000-0001-5154-417X","last_name":"Grosjean","first_name":"Galien M"},{"last_name":"Ostermann","first_name":"Markus","full_name":"Ostermann, Markus"},{"full_name":"Sauer, Markus","last_name":"Sauer","first_name":"Markus"},{"full_name":"Hahn, Michael","first_name":"Michael","last_name":"Hahn"},{"first_name":"Christian M.","last_name":"Pichler","full_name":"Pichler, Christian M."},{"full_name":"Fahrnberger, Florian","first_name":"Florian","last_name":"Fahrnberger"},{"last_name":"Pertl","first_name":"Felix","id":"6313aec0-15b2-11ec-abd3-ed67d16139af","full_name":"Pertl, Felix","orcid":"0000-0003-0463-5794"},{"last_name":"Balazs","first_name":"Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","orcid":"0000-0001-7597-043X","full_name":"Balazs, Daniel"},{"first_name":"Mason M.","last_name":"Link","full_name":"Link, Mason M."},{"first_name":"Seong H.","last_name":"Kim","full_name":"Kim, Seong H."},{"full_name":"Schrader, Devin L.","first_name":"Devin L.","last_name":"Schrader"},{"full_name":"Blanco, Adriana","last_name":"Blanco","first_name":"Adriana"},{"first_name":"Francisco","last_name":"Gracia","full_name":"Gracia, Francisco"},{"first_name":"Nicolás","last_name":"Mujica","full_name":"Mujica, Nicolás"},{"id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","full_name":"Waitukaitis, Scott R","orcid":"0000-0002-2299-3176","last_name":"Waitukaitis","first_name":"Scott R"}],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"abstract":[{"text":"Insulating oxides are among the most abundant solid materials in the universe1,2,3. Of the many ways in which they influence natural phenomena, perhaps the most consequential is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which occurs even between samples of the same oxide—yet the symmetry-breaking parameter that causes this remains unidentified11,12. Here we show that adventitious carbonaceous molecules adsorbed from the environment are the symmetry-breaking factor in same-material oxide contact electrification (CE). We use acoustic levitation to measure charge exchange between a sphere and a plate composed of identical amorphous silicon dioxide (SiO2). Although charging polarity is random for co-prepared samples, we control it with baking or plasma treatment. Observing the charge-exchange relaxation afterwards, we see dynamics over a timescale of hours and connect this directly to the presence of adventitious carbon with time-of-flight mass spectrometry, low-energy ion scattering and infrared spectroscopy. Going further, we confirm that adventitious carbon can even determine charge exchange among different oxides. Our results identify the symmetry-breaking parameter that causes insulating oxides to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6, while simultaneously highlighting an overlooked factor in CE more broadly.","lang":"eng"}],"PlanS_conform":"1","department":[{"_id":"ScWa"},{"_id":"GradSch"},{"_id":"LifeSc"}],"ec_funded":1,"_id":"21485","project":[{"name":"Tribocharge: a multi-scale approach to an enduring problem in physics","grant_number":"949120","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","call_identifier":"H2020"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships"}],"oa_version":"Published Version","article_type":"original","page":"626-631","oa":1,"related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/"}]},"file":[{"file_name":"2026_Nature_Grosjean.pdf","file_size":12245694,"date_updated":"2026-03-24T06:57:08Z","content_type":"application/pdf","file_id":"21494","relation":"main_file","access_level":"open_access","creator":"dernst","success":1,"date_created":"2026-03-24T06:57:08Z","checksum":"dafef9ed575b44be4263e948a47ae056"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2026","volume":651,"publication_status":"published","date_updated":"2026-04-28T12:06:01Z","file_date_updated":"2026-03-24T06:57:08Z","publication":"Nature","quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","publisher":"Springer Nature","language":[{"iso":"eng"}],"pmid":1,"month":"03","intvolume":"       651","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"ama":"Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. 2026;651(8106):626-631. doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>","ieee":"G. M. Grosjean <i>et al.</i>, “Adventitious carbon breaks symmetry in oxide contact electrification,” <i>Nature</i>, vol. 651, no. 8106. Springer Nature, pp. 626–631, 2026.","chicago":"Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>.","mla":"Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>, vol. 651, no. 8106, Springer Nature, 2026, pp. 626–31, doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>.","ista":"Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification. Nature. 651(8106), 626–631.","apa":"Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger, F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>","short":"G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger, F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia, N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631."},"date_published":"2026-03-18T00:00:00Z","has_accepted_license":"1","status":"public","date_created":"2026-03-23T15:04:00Z","doi":"10.1038/s41586-025-10088-w","acknowledgement":"This project has received support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant agreement no. 754411). We acknowledge the state of Lower Austria and the European Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing facility and Lab Support Facility. We thank the Modic group for the use of the Laue camera, T. Zauner for the photography of the experimental set-up and R. Möller for insightful discussions. Open access funding provided by Institute of Science and Technology (IST Austria).","type":"journal_article","day":"18","issue":"8106","title":"Adventitious carbon breaks symmetry in oxide contact electrification","OA_type":"hybrid","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"ddc":["540"],"corr_author":"1"},{"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"qrag003","citation":{"mla":"Layana Franco, Lorena Alexandra, et al. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” <i>Evolution Letters</i>, qrag003, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/evlett/qrag003\">10.1093/evlett/qrag003</a>.","ama":"Layana Franco LA, Toups MA, Vicoso B. Causes and consequences of sex-chromosome turnovers in Diptera. <i>Evolution Letters</i>. 2026. doi:<a href=\"https://doi.org/10.1093/evlett/qrag003\">10.1093/evlett/qrag003</a>","ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Causes and consequences of sex-chromosome turnovers in Diptera,” <i>Evolution Letters</i>. Oxford University Press, 2026.","chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” <i>Evolution Letters</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/evlett/qrag003\">https://doi.org/10.1093/evlett/qrag003</a>.","short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, Evolution Letters (2026).","ista":"Layana Franco LA, Toups MA, Vicoso B. 2026. Causes and consequences of sex-chromosome turnovers in Diptera. Evolution Letters., qrag003.","apa":"Layana Franco, L. A., Toups, M. A., &#38; Vicoso, B. (2026). Causes and consequences of sex-chromosome turnovers in Diptera. <i>Evolution Letters</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/evlett/qrag003\">https://doi.org/10.1093/evlett/qrag003</a>"},"date_published":"2026-03-12T00:00:00Z","quality_controlled":"1","article_processing_charge":"Yes","publication":"Evolution Letters","month":"03","OA_place":"publisher","publisher":"Oxford University Press","language":[{"iso":"eng"}],"title":"Causes and consequences of sex-chromosome turnovers in Diptera","OA_type":"gold","publication_identifier":{"eissn":["2056-3744"]},"ddc":["570"],"corr_author":"1","doi":"10.1093/evlett/qrag003","date_created":"2026-03-23T15:05:42Z","main_file_link":[{"url":"https://doi.org/10.1093/evlett/qrag003","open_access":"1"}],"status":"public","has_accepted_license":"1","day":"12","type":"journal_article","acknowledgement":"This work was supported by a grant from the Austrian Science Fund (FWF, grant number PAT 8748323) to B.V. We thank the Vicoso group for their feedback on an early version of the manuscript. We are grateful to Kamil Jaron and Julia Gries for helpful discussions and for sharing their unpublished work. Computational resources and support were provided by the Scientific Computing Unit at ISTA.","DOAJ_listed":"1","oa_version":"Published Version","_id":"21486","project":[{"name":"Sex chromosomes in evolution and development","_id":"8ed82125-16d5-11f0-9cad-fbcae312235b","grant_number":"PAT 8748323"}],"oa":1,"article_type":"original","abstract":[{"lang":"eng","text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analyzed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find that the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on Muller element F (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes."}],"author":[{"orcid":"0000-0002-1253-6297","full_name":"Layana Franco, Lorena Alexandra","id":"02814589-eb8f-11eb-b029-a70074f3f18f","first_name":"Lorena Alexandra","last_name":"Layana Franco"},{"first_name":"Melissa A","last_name":"Toups","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87"},{"id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz","orcid":"0000-0002-4579-8306","last_name":"Vicoso","first_name":"Beatriz"}],"department":[{"_id":"BeVi"},{"_id":"GradSch"}],"date_updated":"2026-03-24T07:14:08Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"epub_ahead","year":"2026"},{"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.xgen.2026.101162"}],"doi":"10.1016/j.xgen.2026.101162","date_created":"2026-03-23T15:10:03Z","status":"public","has_accepted_license":"1","type":"journal_article","day":"18","acknowledgement":"We thank Malgorzata Borczyk for creating the gene burden scores. We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter, Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for providing valuable suggestions and comments on earlier versions of the work. This project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364), and core funding from ISTA. High-performance computing was supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp). We would like to acknowledge the participants and investigators of the UK Biobank study. We gratefully acknowledge the All of Us participants for their contributions, without whom this research would not have been possible. We also thank the National Institutes of Health All of Us Research Program for making available the participant data (and/or samples and/or cohort) examined in this study.","DOAJ_listed":"1","title":"Joint modeling of whole-genome sequencing data for human height via approximate message passing","OA_type":"gold","publication_identifier":{"eissn":["2666-979X"]},"ddc":["000","570"],"corr_author":"1","quality_controlled":"1","article_processing_charge":"Yes","publication":"Cell Genomics","month":"02","OA_place":"publisher","publisher":"Elsevier","language":[{"iso":"eng"}],"tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"article_number":"101162","citation":{"short":"A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics (2026).","ista":"Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome sequencing data for human height via approximate message passing. Cell Genomics., 101162.","apa":"Depope, A., Bajzik, J., Mondelli, M., &#38; Robinson, M. R. (2026). Joint modeling of whole-genome sequencing data for human height via approximate message passing. <i>Cell Genomics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">https://doi.org/10.1016/j.xgen.2026.101162</a>","mla":"Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” <i>Cell Genomics</i>, 101162, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">10.1016/j.xgen.2026.101162</a>.","ieee":"A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of whole-genome sequencing data for human height via approximate message passing,” <i>Cell Genomics</i>. Elsevier, 2026.","chicago":"Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” <i>Cell Genomics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">https://doi.org/10.1016/j.xgen.2026.101162</a>.","ama":"Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome sequencing data for human height via approximate message passing. <i>Cell Genomics</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">10.1016/j.xgen.2026.101162</a>"},"date_published":"2026-02-18T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","related_material":{"link":[{"url":"https://ista.ac.at/en/news/big-data-and-human-height/","relation":"press_release","description":"News on ISTA website"}]},"publication_status":"epub_ahead","year":"2026","date_updated":"2026-04-28T12:08:37Z","abstract":[{"text":"Human height is a model for the genetic analysis of complex traits, and recent studies suggest the presence of thousands of common genetic variant associations and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic paradigm based on approximate message passing (genomic vector approximate message passing [gVAMP]) for identifying DNA sequence variants associated with complex traits and common diseases in large-scale whole-genome sequencing (WGS) data. We show that gVAMP accurately localizes associations to variants with the correct frequency and position in the DNA, outperforming existing fine-mapping methods in selecting the appropriate genetic variants within WGS data. We then apply gVAMP to jointly model the relationship of tens of millions of WGS variants with human height in hundreds of thousands of UK Biobank individuals. We identify 59 rare variants and gene burden scores alongside many hundreds of DNA regions containing common variant associations and show that understanding the genetic basis of complex traits will require the joint analysis of hundreds of millions of variables measured on millions of people. The polygenic risk scores obtained from gVAMP have high accuracy (including a prediction accuracy of ∼46% for human height) and outperform current methods for downstream tasks such as mixed linear model association testing across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation for a wider range of analyses in WGS data.","lang":"eng"}],"author":[{"first_name":"Al","last_name":"Depope","full_name":"Depope, Al","id":"0b77531d-dbcd-11ea-9d1d-a8eee0bf3830"},{"first_name":"Jakub","last_name":"Bajzik","full_name":"Bajzik, Jakub","id":"b995e25b-8c4b-11ed-a6d8-f71b7bcd6122"},{"id":"27EB676C-8706-11E9-9510-7717E6697425","full_name":"Mondelli, Marco","orcid":"0000-0002-3242-7020","last_name":"Mondelli","first_name":"Marco"},{"full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","first_name":"Matthew Richard","last_name":"Robinson"}],"department":[{"_id":"MaMo"},{"_id":"MaRo"}],"oa_version":"Published Version","project":[{"_id":"059876FA-7A3F-11EA-A408-12923DDC885E","name":"Prix Lopez-Loretta 2019 - Marco Mondelli"},{"name":"Inference in High Dimensions: Light-speed Algorithms and Information Limits","grant_number":"101161364","_id":"911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf"},{"name":"Improving estimation and prediction of common complex disease risk","grant_number":"PCEGP3_181181","_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A"}],"_id":"21488","oa":1,"article_type":"original"},{"oa_version":"None","project":[{"name":"Geometry of the tip of the global nilpotent cone","grant_number":"P35847","_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3"}],"_id":"21489","oa":1,"abstract":[{"lang":"eng","text":"We study Kirillov algebras attached to minuscule highest weight representations of semisimple Lie algebras. They can be viewed as equivariant cohomology algebras of partial flag varieties. Real structures on the varieties then induce involutions of these algebras. We describe how these involutions act on the spectra of minuscule Kirillov algebras, and model the fixed points via the equivariant cohomology of real partial flag varieties. We then use this model to characterise freeness of the fixed point coordinate ring over the appropriate base. As an application, we recover a q = -1 phenomenon of Stembridge in the minuscule case by geometric means."}],"external_id":{"arxiv":["2411.16270"]},"author":[{"full_name":"Elkner, Mischa M","id":"477faa59-080d-11ed-979a-c693ab7638ab","first_name":"Mischa M","last_name":"Elkner"}],"department":[{"_id":"TaHa"}],"date_updated":"2026-03-24T08:26:10Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"epub_ahead","year":"2026","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"short":"M.M. Elkner, Transformation Groups (2026).","ista":"Elkner MM. 2026. On involutions of minuscule Kirillov algebras induced by real structures. Transformation Groups.","apa":"Elkner, M. M. (2026). On involutions of minuscule Kirillov algebras induced by real structures. <i>Transformation Groups</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00031-026-09958-y\">https://doi.org/10.1007/s00031-026-09958-y</a>","mla":"Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by Real Structures.” <i>Transformation Groups</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s00031-026-09958-y\">10.1007/s00031-026-09958-y</a>.","ama":"Elkner MM. On involutions of minuscule Kirillov algebras induced by real structures. <i>Transformation Groups</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s00031-026-09958-y\">10.1007/s00031-026-09958-y</a>","chicago":"Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by Real Structures.” <i>Transformation Groups</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00031-026-09958-y\">https://doi.org/10.1007/s00031-026-09958-y</a>.","ieee":"M. M. Elkner, “On involutions of minuscule Kirillov algebras induced by real structures,” <i>Transformation Groups</i>. Springer Nature, 2026."},"date_published":"2026-03-14T00:00:00Z","quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","publication":"Transformation Groups","month":"03","publisher":"Springer Nature","language":[{"iso":"eng"}],"title":"On involutions of minuscule Kirillov algebras induced by real structures","publication_identifier":{"eissn":["1531-586X"],"issn":["1083-4362"]},"corr_author":"1","ddc":["510"],"arxiv":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s00031-026-09958-y"}],"doi":"10.1007/s00031-026-09958-y","date_created":"2026-03-23T15:10:43Z","status":"public","has_accepted_license":"1","type":"journal_article","day":"14","acknowledgement":"I would like to thank Tamás Hausel for introducing me to this area of mathematics and for his constant guidance. I would also like to thank Jakub Löwit and Miguel González for fruitful discussions and many helpful comments on this paper. This work was done during the author’s PhD studies at the Institute of Science and Technology Austria (ISTA). It was funded by the Austrian Science Fund (FWF) 10.55776/P35847. Open access funding provided by Institute of Science and Technology (IST Austria). "},{"author":[{"full_name":"Li, Mingyue","id":"01f96916-0235-11eb-9379-a323192643b7","first_name":"Mingyue","last_name":"Li"},{"full_name":"Rydza, Nikola","first_name":"Nikola","last_name":"Rydza"},{"full_name":"Mazur, Ewa","first_name":"Ewa","last_name":"Mazur"},{"id":"34F1AF46-F248-11E8-B48F-1D18A9856A87","full_name":"Molnar, Gergely","last_name":"Molnar","first_name":"Gergely"},{"last_name":"Nodzyński","first_name":"Tomasz","full_name":"Nodzyński, Tomasz"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří"}],"external_id":{"pmid":["41831441"]},"abstract":[{"lang":"eng","text":"Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developmental importance of canalization, the molecular components linking auxin perception to the regulation of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel and essential component of auxin canalization that links intracellular auxin signaling with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23 transcriptional auxin signaling. tow mutants exhibit defects in regeneration and de novo vasculature formation, along with impaired formation of polarized, PIN-expressing auxin channels. At the subcellular level, these mutants display disrupted auxin-induced PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes predominantly to the plasma membrane, where it interacts with receptor-like kinases involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at the cell surface. Together, our findings identify TOW as a molecular link between intracellular and cell surface auxin signaling mechanisms that converge on PIN trafficking and polarity, providing new insights into how auxin signaling regulates directional auxin transport for the self-organizing formation of vasculature during flexible plant development."}],"acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"Bio"},{"_id":"LifeSc"}],"PlanS_conform":"1","department":[{"_id":"JiFr"}],"project":[{"grant_number":"101142681","_id":"8f347782-16d5-11f0-9cad-8c19706ee739","name":"Cyclic nucleotides as second messengers in plants"},{"grant_number":"E271","_id":"bd906599-d553-11ed-ba76-abf8547645d7","name":"Identification of a novel regulator in auxin canalization"}],"_id":"21490","oa_version":"Published Version","page":"1468-1480.e6","article_type":"original","oa":1,"file":[{"access_level":"open_access","creator":"dernst","success":1,"date_created":"2026-03-24T08:34:37Z","checksum":"fe6c41fdab58a55df5f2a5860c02acdc","file_name":"2026_CurrentBiology_Li.pdf","file_size":12986894,"date_updated":"2026-03-24T08:34:37Z","content_type":"application/pdf","file_id":"21496","relation":"main_file"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":36,"year":"2026","publication_status":"published","date_updated":"2026-03-24T08:36:40Z","file_date_updated":"2026-03-24T08:34:37Z","publication":"Current Biology","article_processing_charge":"Yes (via OA deal)","quality_controlled":"1","language":[{"iso":"eng"}],"publisher":"Elsevier","OA_place":"publisher","month":"03","pmid":1,"intvolume":"        36","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_published":"2026-03-23T00:00:00Z","citation":{"chicago":"Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński, and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>.","ieee":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization,” <i>Current Biology</i>, vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026.","ama":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. 2026;36(6):1468-1480.e6. doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>","mla":"Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>, vol. 36, no. 6, Elsevier, 2026, p. 1468–1480.e6, doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>.","ista":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. Current Biology. 36(6), 1468–1480.e6.","apa":"Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., &#38; Friml, J. (2026). Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>","short":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology 36 (2026) 1468–1480.e6."},"status":"public","has_accepted_license":"1","doi":"10.1016/j.cub.2026.02.023","date_created":"2026-03-23T15:11:16Z","acknowledgement":"We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9 system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof. Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions, and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging & Optics Facility, and the Lab Support Facility at the Institute of Science and Technology Austria. This research was supported by the Scientific Service Units (SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The work conducted by the Friml group was funded by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS) and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant Sciences Core Facility of CEITEC Masaryk University. E.M. received support from the National Science Centre (NCN), Poland, through the OPUS call within the Weave programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes Amos Comenius.","type":"journal_article","day":"23","OA_type":"hybrid","issue":"6","title":"Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization","corr_author":"1","ddc":["580"],"publication_identifier":{"issn":["0960-9822"]}},{"article_type":"original","oa":1,"_id":"21501","project":[{"call_identifier":"H2020","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","grant_number":"850899","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control"}],"ec_funded":1,"oa_version":"Published Version","PlanS_conform":"1","department":[{"_id":"MaSe"}],"author":[{"id":"04b4791c-8fd7-11ee-a7df-be2fdc569c48","full_name":"Nicolau Jimenez, Eulalia","last_name":"Nicolau Jimenez","first_name":"Eulalia"},{"orcid":"0000-0003-0038-7068","full_name":"Ljubotina, Marko","id":"F75EE9BE-5C90-11EA-905D-16643DDC885E","first_name":"Marko","last_name":"Ljubotina"},{"first_name":"Maksym","last_name":"Serbyn","full_name":"Serbyn, Maksym","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"}],"external_id":{"arxiv":["2504.17627"]},"abstract":[{"lang":"eng","text":"Kinetically constrained models were originally introduced to capture slow relaxation in glassy systems, where dynamics are hindered by local constraints instead of energy barriers. Their quantum counterparts have recently drawn attention for exhibiting highly degenerate eigenstates at zero energy—known as zero modes—stemming from chiral symmetry. Yet, the structure and implications of these zero modes remain poorly understood. In this work, we focus on the properties of the zero mode subspace in quantum kinetically constrained models with a U(1) particle-conservation symmetry. We use the U(1) East, which lacks inversion symmetry, and the inversion-symmetric U(1) East-West models to illustrate our two main results. First, we observe that the simultaneous presence of constraints and chiral symmetry generally leads to a parametric increase in the number of zero modes due to the fragmentation of the many-body\r\nHilbert space into disconnected sectors. Second, we generalize the concept of compact localized states from single-particle physics and introduce the notion of collective bound states, a special kind of nonergodic eigenstates that are robust to enlarging the system size. We formulate sufficient criteria for their existence, arguing that the degenerate zero mode subspace plays a central role, and demonstrate bound states in both example models and in a two-dimensional model, the U(1) North-East, and in the pairflip model, a system without particle conservation. Our results motivate a systematic study of bound states and their relation to ergodicity breaking, transport, and other properties of quantum kinetically constrained\r\nmodels. "}],"file_date_updated":"2026-03-30T06:08:07Z","date_updated":"2026-03-30T06:09:28Z","year":"2026","volume":7,"publication_status":"published","file":[{"creator":"dernst","success":1,"date_created":"2026-03-30T06:08:07Z","checksum":"d155ffa9e1a8275702149165f4bf963c","access_level":"open_access","file_size":1848724,"date_updated":"2026-03-30T06:08:07Z","file_id":"21505","content_type":"application/pdf","relation":"main_file","file_name":"2026_PRXQuantum_Nicolau.pdf"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-03-13T00:00:00Z","citation":{"short":"E. Nicolau Jimenez, M. Ljubotina, M. Serbyn, PRX Quantum 7 (2026).","ista":"Nicolau Jimenez E, Ljubotina M, Serbyn M. 2026. Fragmentation, zero modes, and collective bound states in constrained models. PRX Quantum. 7, 010352.","apa":"Nicolau Jimenez, E., Ljubotina, M., &#38; Serbyn, M. (2026). Fragmentation, zero modes, and collective bound states in constrained models. <i>PRX Quantum</i>. American Physical Society. <a href=\"https://doi.org/10.1103/sl79-1xgb\">https://doi.org/10.1103/sl79-1xgb</a>","mla":"Nicolau Jimenez, Eulalia, et al. “Fragmentation, Zero Modes, and Collective Bound States in Constrained Models.” <i>PRX Quantum</i>, vol. 7, 010352, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/sl79-1xgb\">10.1103/sl79-1xgb</a>.","ama":"Nicolau Jimenez E, Ljubotina M, Serbyn M. Fragmentation, zero modes, and collective bound states in constrained models. <i>PRX Quantum</i>. 2026;7. doi:<a href=\"https://doi.org/10.1103/sl79-1xgb\">10.1103/sl79-1xgb</a>","chicago":"Nicolau Jimenez, Eulalia, Marko Ljubotina, and Maksym Serbyn. “Fragmentation, Zero Modes, and Collective Bound States in Constrained Models.” <i>PRX Quantum</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/sl79-1xgb\">https://doi.org/10.1103/sl79-1xgb</a>.","ieee":"E. Nicolau Jimenez, M. Ljubotina, and M. Serbyn, “Fragmentation, zero modes, and collective bound states in constrained models,” <i>PRX Quantum</i>, vol. 7. American Physical Society, 2026."},"article_number":"010352","intvolume":"         7","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"publisher":"American Physical Society","OA_place":"publisher","month":"03","publication":"PRX Quantum","article_processing_charge":"Yes","quality_controlled":"1","corr_author":"1","ddc":["530"],"scopus_import":"1","publication_identifier":{"eissn":["2691-3399"]},"OA_type":"gold","title":"Fragmentation, zero modes, and collective bound states in constrained models","DOAJ_listed":"1","acknowledgement":"The authors acknowledge useful discussions with Berislav Buca. This work was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899). M.L. acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC-2111—390814868. This research was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP).","day":"13","type":"journal_article","status":"public","has_accepted_license":"1","doi":"10.1103/sl79-1xgb","date_created":"2026-03-28T14:57:56Z","arxiv":1},{"oa_version":"Published Version","_id":"21502","oa":1,"article_type":"original","abstract":[{"lang":"eng","text":"The mammalian brain stores glucose, the main circulating energy substrate, as glycogen. In rodents, the cerebellum contains relatively high glycogen levels, yet its cellular and subcellular distribution remains poorly defined. Using monoclonal antibodies against glycogen, we examined its distribution in the mouse cerebellar cortex. Glycogen was predominantly localized to Bergmann glia (BG) processes in the molecular layer and was also detected in Purkinje cells (PCs), the principal cerebellar neurons. To assess the functional significance of cerebellar glycogen, we analyzed behavior in mice lacking glycogen synthase 1 (Gys1) in BG or PCs using a floxed Gys1 line. Gys1 deficiency in either PCs or GFAP-positive cells reduced anxiety-like behavior, whereas combined deletion caused PC degeneration and ataxia. These findings reveal a critical role for glycogen metabolism in both astrocytes and neurons in cerebellar function."}],"external_id":{"pmid":["41890976"]},"author":[{"full_name":"Akther, Sonam","last_name":"Akther","first_name":"Sonam"},{"full_name":"Lee, Ashley Bomin","last_name":"Lee","first_name":"Ashley Bomin"},{"full_name":"Konno, Ayumu","last_name":"Konno","first_name":"Ayumu"},{"full_name":"Asiminas, Antonis","first_name":"Antonis","last_name":"Asiminas"},{"last_name":"Vittani","first_name":"Marta","full_name":"Vittani, Marta"},{"full_name":"Mishima, Tsuneko","last_name":"Mishima","first_name":"Tsuneko"},{"last_name":"Hirai","first_name":"Hirokazu","full_name":"Hirai, Hirokazu"},{"first_name":"Claire Francesca","last_name":"Meehan","full_name":"Meehan, Claire Francesca"},{"first_name":"Jordi","last_name":"Duran","full_name":"Duran, Jordi"},{"last_name":"Guinovart","first_name":"Joan","full_name":"Guinovart, Joan"},{"full_name":"Ashida, Hitoshi","first_name":"Hitoshi","last_name":"Ashida"},{"full_name":"Morita, Tsuyoshi","last_name":"Morita","first_name":"Tsuyoshi"},{"full_name":"Baba, Otto","first_name":"Otto","last_name":"Baba"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi"},{"first_name":"Maiken","last_name":"Nedergaard","full_name":"Nedergaard, Maiken"},{"first_name":"Hajime","last_name":"Hirase","full_name":"Hirase, Hajime"}],"department":[{"_id":"RySh"}],"date_updated":"2026-06-18T08:32:22Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"epub_ahead","volume":29,"year":"2026","article_number":"115192","intvolume":"        29","citation":{"mla":"Akther, Sonam, et al. “Distribution and Functional Significance of Rodent Cerebellar Glycogen.” <i>IScience</i>, vol. 29, no. 4, 115192, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.isci.2026.115192\">10.1016/j.isci.2026.115192</a>.","chicago":"Akther, Sonam, Ashley Bomin Lee, Ayumu Konno, Antonis Asiminas, Marta Vittani, Tsuneko Mishima, Hirokazu Hirai, et al. “Distribution and Functional Significance of Rodent Cerebellar Glycogen.” <i>IScience</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.isci.2026.115192\">https://doi.org/10.1016/j.isci.2026.115192</a>.","ieee":"S. Akther <i>et al.</i>, “Distribution and functional significance of rodent cerebellar glycogen,” <i>iScience</i>, vol. 29, no. 4. Elsevier, 2026.","ama":"Akther S, Lee AB, Konno A, et al. Distribution and functional significance of rodent cerebellar glycogen. <i>iScience</i>. 2026;29(4). doi:<a href=\"https://doi.org/10.1016/j.isci.2026.115192\">10.1016/j.isci.2026.115192</a>","short":"S. Akther, A.B. Lee, A. Konno, A. Asiminas, M. Vittani, T. Mishima, H. Hirai, C.F. Meehan, J. Duran, J. Guinovart, H. Ashida, T. Morita, O. Baba, R. Shigemoto, M. Nedergaard, H. Hirase, IScience 29 (2026).","apa":"Akther, S., Lee, A. B., Konno, A., Asiminas, A., Vittani, M., Mishima, T., … Hirase, H. (2026). Distribution and functional significance of rodent cerebellar glycogen. <i>IScience</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.isci.2026.115192\">https://doi.org/10.1016/j.isci.2026.115192</a>","ista":"Akther S, Lee AB, Konno A, Asiminas A, Vittani M, Mishima T, Hirai H, Meehan CF, Duran J, Guinovart J, Ashida H, Morita T, Baba O, Shigemoto R, Nedergaard M, Hirase H. 2026. Distribution and functional significance of rodent cerebellar glycogen. iScience. 29(4), 115192."},"date_published":"2026-03-17T00:00:00Z","quality_controlled":"1","article_processing_charge":"Yes","publication":"iScience","month":"03","pmid":1,"publisher":"Elsevier","OA_place":"publisher","language":[{"iso":"eng"}],"issue":"4","title":"Distribution and functional significance of rodent cerebellar glycogen","OA_type":"gold","scopus_import":"1","publication_identifier":{"eissn":["2589-0042"]},"ddc":["570"],"date_created":"2026-03-29T22:07:07Z","doi":"10.1016/j.isci.2026.115192","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.isci.2026.115192"}],"status":"public","day":"17","type":"journal_article","acknowledgement":"This work was supported by the Novo Nordisk Foundation (NNFOC0058058, H. Hirase), the Danmarks Frie Forskningsfond (0134-00107B and 5283-00069A, H.Hirase), the Lundbeck Foundation, Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research (KAKENHI) program (22K06454/24H01221, A.K.; 23K27482, H.Hirai), the Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) (JP21dm0207111, H. Hirai), AMED Brain/MINDS 2.0 (JP23wm0625001 and JP24wm0625103, H. Hirai), and grants from the Spanish Ministerio de Ciencia e Innovación (MCIU/FEDER/AEI) (PID2020-118699 GB-100, J.D.) and the Fundación Ramón Areces (J.D.). Sonam Akther has been supported by the RIKEN IPA fellowship. We are thankful to Dr. Yuki Oe for his support in the initial stage of this study and to Dan Xue for his help with the graphical abstract. We thank Dr. Pia Weikop for providing CTN research infrastructure. The authors declare no competing financial interests.","DOAJ_listed":"1"},{"OA_type":"hybrid","issue":"2","title":"Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants","ddc":["570"],"scopus_import":"1","publication_identifier":{"issn":[" 1470-269X"],"eissn":["1473-1150"]},"status":"public","has_accepted_license":"1","doi":"10.1038/s41397-026-00399-0","date_created":"2026-03-29T22:07:08Z","acknowledgement":"This research has been conducted using the UK Biobank Resource under Application Number 62979. We are grateful to the UK Biobank and all its voluntary participants. This work used data provided by patients and collected by the NHS as part of their care and support.\r\n\r\nThis study was funded by the National Science Center, Poland: PRELUDIUM BIS-3 grant no. 2021/43/O/NZ7/01187 (development and benchmarking of variant scores) and SONATINA 5 grant 2021/40/C/NZ2/00218 (UKB analyses). Additional support came from the statutory funds of the Maj Institute of Pharmacology PAS. We gratefully acknowledge Poland’s high-performance Infrastructure PLGrid ACK Cyfronet AGH, for providing computer facilities and support within computational grant no PLG/2022/015861. DMF and GEB were funded by NIH grants NIH R35GM152106 and UM1HG011969.","type":"journal_article","day":"09","intvolume":"        26","article_number":"8","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"date_published":"2026-03-09T00:00:00Z","citation":{"apa":"Hajto, J., Piechota, M., Krätschmer, I., Konowalska, P., Boyle, G. E., Fowler, D. M., … Korostynski, M. (2026). Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>","ista":"Hajto J, Piechota M, Krätschmer I, Konowalska P, Boyle GE, Fowler DM, Borczyk M, Korostynski M. 2026. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. Pharmacogenomics Journal. 26(2), 8.","short":"J. Hajto, M. Piechota, I. Krätschmer, P. Konowalska, G.E. Boyle, D.M. Fowler, M. Borczyk, M. Korostynski, Pharmacogenomics Journal 26 (2026).","ieee":"J. Hajto <i>et al.</i>, “Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants,” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2. Springer Nature, 2026.","chicago":"Hajto, Jacek, Marcin Piechota, Ilse Krätschmer, Paula Konowalska, Gabriel E. Boyle, Douglas M. Fowler, Malgorzata Borczyk, and Michal Korostynski. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>.","ama":"Hajto J, Piechota M, Krätschmer I, et al. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. 2026;26(2). doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>","mla":"Hajto, Jacek, et al. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2, 8, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>."},"publication":"Pharmacogenomics Journal","article_processing_charge":"Yes (in subscription journal)","quality_controlled":"1","language":[{"iso":"eng"}],"publisher":"Springer Nature","OA_place":"publisher","month":"03","pmid":1,"date_updated":"2026-03-30T07:10:50Z","file_date_updated":"2026-03-30T07:04:08Z","file":[{"file_size":2618963,"date_updated":"2026-03-30T07:04:08Z","content_type":"application/pdf","file_id":"21506","relation":"main_file","file_name":"2026_PharmacogenomicsJour_Hajto.pdf","creator":"dernst","success":1,"date_created":"2026-03-30T07:04:08Z","checksum":"2fd3d7e48b779ac24245f6c35449b89a","access_level":"open_access"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":26,"year":"2026","publication_status":"published","_id":"21503","oa_version":"Published Version","article_type":"original","oa":1,"author":[{"full_name":"Hajto, Jacek","last_name":"Hajto","first_name":"Jacek"},{"last_name":"Piechota","first_name":"Marcin","full_name":"Piechota, Marcin"},{"first_name":"Ilse","last_name":"Krätschmer","orcid":"0000-0002-5636-9259","full_name":"Krätschmer, Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73"},{"full_name":"Konowalska, Paula","last_name":"Konowalska","first_name":"Paula"},{"full_name":"Boyle, Gabriel E.","last_name":"Boyle","first_name":"Gabriel E."},{"full_name":"Fowler, Douglas M.","last_name":"Fowler","first_name":"Douglas M."},{"first_name":"Malgorzata","last_name":"Borczyk","full_name":"Borczyk, Malgorzata"},{"full_name":"Korostynski, Michal","first_name":"Michal","last_name":"Korostynski"}],"external_id":{"pmid":["41803106"]},"abstract":[{"text":"Currently, pharmacogenetics relies on partially annotated star alleles, leaving novel variants and complex haplotypes uninterpretable. Computational scoring frameworks could overcome these limitations. Here, we comprehensively evaluated the ability of existing (CADD, FATHMM-XF, PROVEAN, MutationAssessor, SIFT, PhyloP100, APF, APF2) and novel (PharmGScore and PharmMLScore) variant effect predictors to assess pharmacogenetic alleles in multiple scenarios. Altogether we analyzed 541 PharmVar alleles, high‑throughput CYP2C9 and CYP2C19 mutational maps, and 200 642 UK Biobank exomes linked with health records containing antidepressant treatment outcomes. Many evaluated tools, especially ensemble frameworks, matched or exceeded star allele classifications (ROC‑AUC up to 0.85 for allele definitions, 0.95 in vitro; TPR up to 0.99 for exomes) and accurately predicted severe antidepressant adverse events for carriers of deleterious variants in CYP2C19 (OR 1.20–1.35). Our findings show that computational predictors deliver star allele accuracy while overcoming their limitations. With additional validation, computational tools could enhance clinical decision frameworks by enabling continuous scoring, incorporating previously unknown variants, and providing genome-wide applicability.","lang":"eng"}],"department":[{"_id":"MaRo"}]},{"department":[{"_id":"JaMa"}],"abstract":[{"lang":"eng","text":"Selecting an appropriate divergence measure is a critical aspect of machine learning, as it directly impacts model performance. Among the most widely used, we find the Kullback–Leibler (KL) divergence, originally introduced in kinetic theory as a measure of relative entropy between probability distributions. Just as in machine learning, the ability to quantify the proximity of probability distributions plays a central role in kinetic theory. In this paper, we present a comparative review of divergence measures rooted in kinetic theory, highlighting their theoretical foundations and exploring their potential applications in machine learning and artificial intelligence."}],"author":[{"first_name":"Gennaro","last_name":"Auricchio","full_name":"Auricchio, Gennaro"},{"last_name":"Brigati","first_name":"Giovanni","id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1","full_name":"Brigati, Giovanni"},{"full_name":"Giudici, Paolo","first_name":"Paolo","last_name":"Giudici"},{"full_name":"Toscani, Giuseppe","first_name":"Giuseppe","last_name":"Toscani"}],"external_id":{"arxiv":["2507.11387"]},"oa":1,"article_type":"original","oa_version":"Preprint","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413"}],"_id":"21504","ec_funded":1,"publication_status":"epub_ahead","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-03-30T06:56:35Z","month":"03","language":[{"iso":"eng"}],"publisher":"World Scientific Publishing","OA_place":"repository","article_processing_charge":"No","quality_controlled":"1","publication":"Mathematical Models and Methods in Applied Sciences","date_published":"2026-03-14T00:00:00Z","citation":{"mla":"Auricchio, Gennaro, et al. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>, World Scientific Publishing, 2026, doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>.","ieee":"G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties,” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026.","chicago":"Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>.","ama":"Auricchio G, Brigati G, Giudici P, Toscani G. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. 2026. doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>","short":"G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and Methods in Applied Sciences (2026).","apa":"Auricchio, G., Brigati, G., Giudici, P., &#38; Toscani, G. (2026). From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>","ista":"Auricchio G, Brigati G, Giudici P, Toscani G. 2026. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. Mathematical Models and Methods in Applied Sciences."},"type":"journal_article","day":"14","acknowledgement":"This work has been written within the activities of GNCS and GNFM groups of INdAM (Italian\r\nNational Institute of High Mathematics). G.B. has been funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 101034413. P.G. has been funded by the European Union - NextGenerationEU, in the framework of the GRINSGrowing Resilient, INclusive and Sustainable (GRINS PE00000018).","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2507.11387","open_access":"1"}],"arxiv":1,"date_created":"2026-03-29T22:07:08Z","doi":"10.1142/S0218202526410010","status":"public","scopus_import":"1","publication_identifier":{"eissn":["1793-6314"],"issn":["0218-2025"]},"OA_type":"green","title":"From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties"},{"date_updated":"2026-03-30T12:09:08Z","file_date_updated":"2026-03-30T12:04:38Z","file":[{"file_name":"2026_MolecularCell_Weiss.pdf","relation":"main_file","file_id":"21510","content_type":"application/pdf","file_size":9786677,"date_updated":"2026-03-30T12:04:38Z","access_level":"open_access","checksum":"e16a7315b64a706184b177ea1621523c","date_created":"2026-03-30T12:04:38Z","success":1,"creator":"dernst"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","volume":86,"publication_status":"published","_id":"21509","oa_version":"Published Version","page":"625-639.e8","article_type":"original","oa":1,"external_id":{"pmid":["41679301"]},"author":[{"full_name":"Weiss, Joscha","last_name":"Weiss","first_name":"Joscha"},{"first_name":"Luca","last_name":"Vecchia","full_name":"Vecchia, Luca"},{"first_name":"David","last_name":"Domjan","full_name":"Domjan, David"},{"last_name":"Cavadini","first_name":"Simone","full_name":"Cavadini, Simone"},{"first_name":"Anton","last_name":"Sabantsev","full_name":"Sabantsev, Anton"},{"first_name":"Georg","last_name":"Kempf","full_name":"Kempf, Georg"},{"last_name":"Pathare","first_name":"Ganesh R.","full_name":"Pathare, Ganesh R."},{"last_name":"Brackmann","first_name":"Klaus","full_name":"Brackmann, Klaus"},{"full_name":"Michael, Alicia","orcid":"0000-0002-6080-839X","id":"6437c950-2a03-11ee-914d-d6476dd7b75c","first_name":"Alicia","last_name":"Michael"},{"last_name":"Kater","first_name":"Lukas","full_name":"Kater, Lukas"},{"last_name":"Hietter-Pfeiffer","first_name":"Eric","full_name":"Hietter-Pfeiffer, Eric"},{"last_name":"Haddawi","first_name":"Mina","full_name":"Haddawi, Mina"},{"last_name":"Kuber","first_name":"Urja P.","full_name":"Kuber, Urja P."},{"full_name":"Mühlhäusser, Sandra","first_name":"Sandra","last_name":"Mühlhäusser"},{"last_name":"Grand","first_name":"Ralph S.","full_name":"Grand, Ralph S."},{"full_name":"Stadler, Michael B.","first_name":"Michael B.","last_name":"Stadler"},{"full_name":"Deindl, Sebastian","last_name":"Deindl","first_name":"Sebastian"},{"full_name":"Thomä, Nicolas H.","last_name":"Thomä","first_name":"Nicolas H."}],"abstract":[{"lang":"eng","text":"Chromatin remodeling complexes mobilize nucleosomes and promote transcription factor (TF) binding. Using ensemble and single-molecule assays combined with cryo-electron microscopy (cryo-EM), we studied the interaction between pioneer TFs OCT4–SOX2 and the human BRG1/BRM-associated factor (BAF) complex on nucleosomes. BAF engages TF-bound substrates in two orientations, placing OCT4–SOX2 at either the remodeler ENTRY or EXIT site. At the ENTRY site, OCT4–SOX2 initially coexists with BAF without structural interference. However, continued DNA translocation is expected to cause collisions with bound TFs, which can trigger remodeling direction reversals or may induce TF dissociation. To accommodate TFs at the EXIT site, BAF undergoes structural rearrangements, and ensemble assays reveal a nucleosome subpopulation translocating away from TF-binding sites. Moreover, single-molecule experiments show that nucleosome-bound BAF frequently changes remodeling direction, and we identify an ADP-bound remodeler conformation as a potential intermediate. Together, these findings reveal key aspects of the conformational dynamics and remodeling outcomes underlying BAF processing of TF-bound nucleosomes."}],"PlanS_conform":"1","department":[{"_id":"AlMi"}],"title":"The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2","issue":"4","OA_type":"hybrid","scopus_import":"1","publication_identifier":{"issn":["1097-2765"]},"ddc":["570"],"has_accepted_license":"1","status":"public","date_created":"2026-03-30T11:58:48Z","doi":"10.1016/j.molcel.2026.01.021","acknowledgement":"We thank D. Hess, V. Iesmantavicius, and J. Seebacher (FMI Proteomics and Protein Analysis Facility) for mass spectrometry support; S. Smallwood, K. Shimada, D. Klein, and M. Schütz-Stoffregen for technical assistance; J. Côté and C. Lachance for critical discussions; and members of the Thomä lab for helpful feedback. Support for this work was provided to N.H.T. by the European Research Council under the European Union’s Horizon 2020 research program (NucEM, no. 884331), the Novartis Research Foundation, the Swiss National Science Foundation (SNF 31003A_179541, 310030_214852, and Sinergia CRSII5_186230), and the Swiss Cancer Research (KFS-4980-02-2020 and KFS-5933-08-2023). S.D. was supported by the European Research Council (DONUTS, no. 101092623), the Knut and Alice Wallenberg Foundation (2024.0012), the Cancerfonden (25 4453 Pj), and the Swedish Research Council (VR 03255). A.K.M. was supported by a Human Frontier Science Program Long-Term Fellowship, and L.V. was supported by an EMBO fellowship (ALTF 549-2021).","day":"19","type":"journal_article","intvolume":"        86","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"ama":"Weiss J, Vecchia L, Domjan D, et al. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. 2026;86(4):625-639.e8. doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>","chicago":"Weiss, Joscha, Luca Vecchia, David Domjan, Simone Cavadini, Anton Sabantsev, Georg Kempf, Ganesh R. Pathare, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>.","ieee":"J. Weiss <i>et al.</i>, “The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2,” <i>Molecular Cell</i>, vol. 86, no. 4. Elsevier, p. 625–639.e8, 2026.","mla":"Weiss, Joscha, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>, vol. 86, no. 4, Elsevier, 2026, p. 625–639.e8, doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>.","ista":"Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR, Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser S, Grand RS, Stadler MB, Deindl S, Thomä NH. 2026. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular Cell. 86(4), 625–639.e8.","apa":"Weiss, J., Vecchia, L., Domjan, D., Cavadini, S., Sabantsev, A., Kempf, G., … Thomä, N. H. (2026). The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>","short":"J. Weiss, L. Vecchia, D. Domjan, S. Cavadini, A. Sabantsev, G. Kempf, G.R. Pathare, K. Brackmann, A.K. Michael, L. Kater, E. Hietter-Pfeiffer, M. Haddawi, U.P. Kuber, S. Mühlhäusser, R.S. Grand, M.B. Stadler, S. Deindl, N.H. Thomä, Molecular Cell 86 (2026) 625–639.e8."},"date_published":"2026-02-19T00:00:00Z","publication":"Molecular Cell","quality_controlled":"1","article_processing_charge":"Yes (in subscription journal)","OA_place":"publisher","publisher":"Elsevier","language":[{"iso":"eng"}],"pmid":1,"month":"02"},{"publication_status":"published","volume":13,"year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-05-05T07:53:27Z","abstract":[{"lang":"eng","text":"Recent research in nanophotonics for scintillation-based imaging has demonstrated promising improvements in scintillator performance. In parallel, advances in nanophotonics have enabled wavefront control through metasurfaces, a capability that has transformed fields such as microscopy by allowing tailored control of optical propagation. This naturally raises the following question, which we address in this Perspective: can wavefront-control strategies be leveraged to improve scintillation-based imaging? To answer this question, we explore nanophotonic- and metasurface-enabled wavefront control in scintillators to mitigate image blurring arising from their intrinsically diffuse light emission. While depth-of-field extension in scintillation faces fundamental limitations absent in microscopy, this approach reveals promising avenues, including stacked scintillators, selective spatial-frequency enhancement, and X-ray energy-dependent imaging. These results clarify the key distinctions in adapting wavefront engineering to scintillation and its potential to enable tailored detection strategies."}],"extern":"1","author":[{"full_name":"Chen, Joshua","first_name":"Joshua","last_name":"Chen"},{"full_name":"Vaidya, Sachin","last_name":"Vaidya","first_name":"Sachin"},{"full_name":"Pajovic, Simo","last_name":"Pajovic","first_name":"Simo"},{"first_name":"Seou","last_name":"Choi","full_name":"Choi, Seou"},{"full_name":"Michaels, William","first_name":"William","last_name":"Michaels"},{"full_name":"Martin-Monier, Louis","last_name":"Martin-Monier","first_name":"Louis"},{"first_name":"Juejun","last_name":"Hu","full_name":"Hu, Juejun"},{"full_name":"Cogswell, Carol","first_name":"Carol","last_name":"Cogswell"},{"id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes","first_name":"Charles"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"external_id":{"arxiv":["2601.09830"]},"oa":1,"article_type":"original","page":"1757–1766","oa_version":"Preprint","_id":"21532","day":"01","type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2601.09830"}],"doi":"10.1021/acsphotonics.5c03124","date_created":"2026-03-30T12:22:47Z","arxiv":1,"status":"public","scopus_import":"1","publication_identifier":{"eissn":["2330-4022"]},"OA_type":"green","title":"Wavefront engineering for scintillation-based imaging","issue":"7","month":"03","language":[{"iso":"eng"}],"OA_place":"repository","publisher":"American Chemical Society","article_processing_charge":"No","quality_controlled":"1","publication":"ACS Photonics","date_published":"2026-03-01T00:00:00Z","citation":{"mla":"Chen, Joshua, et al. “Wavefront Engineering for Scintillation-Based Imaging.” <i>ACS Photonics</i>, vol. 13, no. 7, American Chemical Society, 2026, pp. 1757–1766, doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">10.1021/acsphotonics.5c03124</a>.","ama":"Chen J, Vaidya S, Pajovic S, et al. Wavefront engineering for scintillation-based imaging. <i>ACS Photonics</i>. 2026;13(7):1757–1766. doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">10.1021/acsphotonics.5c03124</a>","ieee":"J. Chen <i>et al.</i>, “Wavefront engineering for scintillation-based imaging,” <i>ACS Photonics</i>, vol. 13, no. 7. American Chemical Society, pp. 1757–1766, 2026.","chicago":"Chen, Joshua, Sachin Vaidya, Simo Pajovic, Seou Choi, William Michaels, Louis Martin-Monier, Juejun Hu, Carol Cogswell, Charles Roques-Carmes, and Marin Soljačić. “Wavefront Engineering for Scintillation-Based Imaging.” <i>ACS Photonics</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">https://doi.org/10.1021/acsphotonics.5c03124</a>.","short":"J. Chen, S. Vaidya, S. Pajovic, S. Choi, W. Michaels, L. Martin-Monier, J. Hu, C. Cogswell, C. Roques-Carmes, M. Soljačić, ACS Photonics 13 (2026) 1757–1766.","apa":"Chen, J., Vaidya, S., Pajovic, S., Choi, S., Michaels, W., Martin-Monier, L., … Soljačić, M. (2026). Wavefront engineering for scintillation-based imaging. <i>ACS Photonics</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">https://doi.org/10.1021/acsphotonics.5c03124</a>","ista":"Chen J, Vaidya S, Pajovic S, Choi S, Michaels W, Martin-Monier L, Hu J, Cogswell C, Roques-Carmes C, Soljačić M. 2026. Wavefront engineering for scintillation-based imaging. ACS Photonics. 13(7), 1757–1766."},"intvolume":"        13"},{"ddc":["530"],"scopus_import":"1","publication_identifier":{"eissn":["2047-7538"]},"OA_type":"gold","title":"Three-dimensional nanophotonics with spatially modulated optical properties","type":"journal_article","day":"03","DOAJ_listed":"1","main_file_link":[{"url":"https://doi.org/10.1038/s41377-025-02166-5","open_access":"1"}],"doi":"10.1038/s41377-025-02166-5","date_created":"2026-03-30T12:22:47Z","status":"public","date_published":"2026-03-03T00:00:00Z","citation":{"chicago":"Salamin, Yannick, Gaojie Yang, Brian Mills, André Grossi Fonseca, Charles Roques-Carmes, Quansan Yang, Justin Beroz, et al. “Three-Dimensional Nanophotonics with Spatially Modulated Optical Properties.” <i>Light: Science &#38; Applications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41377-025-02166-5\">https://doi.org/10.1038/s41377-025-02166-5</a>.","ieee":"Y. Salamin <i>et al.</i>, “Three-dimensional nanophotonics with spatially modulated optical properties,” <i>Light: Science &#38; Applications</i>, vol. 15. Springer Nature, 2026.","ama":"Salamin Y, Yang G, Mills B, et al. Three-dimensional nanophotonics with spatially modulated optical properties. <i>Light: Science &#38; Applications</i>. 2026;15. doi:<a href=\"https://doi.org/10.1038/s41377-025-02166-5\">10.1038/s41377-025-02166-5</a>","mla":"Salamin, Yannick, et al. “Three-Dimensional Nanophotonics with Spatially Modulated Optical Properties.” <i>Light: Science &#38; Applications</i>, vol. 15, 145, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41377-025-02166-5\">10.1038/s41377-025-02166-5</a>.","apa":"Salamin, Y., Yang, G., Mills, B., Grossi Fonseca, A., Roques-Carmes, C., Yang, Q., … Soljačić, M. (2026). Three-dimensional nanophotonics with spatially modulated optical properties. <i>Light: Science &#38; Applications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41377-025-02166-5\">https://doi.org/10.1038/s41377-025-02166-5</a>","ista":"Salamin Y, Yang G, Mills B, Grossi Fonseca A, Roques-Carmes C, Yang Q, Beroz J, Kooi SE, de Miguel Comella M, Mak K, Vaidya S, Oran D, Swain C, Sun Y, Maayani S, Sloan J, Amin Elfadil Elawad A, Lopez JJ, Boyden ES, Soljačić M. 2026. Three-dimensional nanophotonics with spatially modulated optical properties. Light: Science &#38; Applications. 15, 145.","short":"Y. Salamin, G. Yang, B. Mills, A. Grossi Fonseca, C. Roques-Carmes, Q. Yang, J. Beroz, S.E. Kooi, M. de Miguel Comella, K. Mak, S. Vaidya, D. Oran, C. Swain, Y. Sun, S. Maayani, J. Sloan, A. Amin Elfadil Elawad, J.J. Lopez, E.S. Boyden, M. Soljačić, Light: Science &#38; Applications 15 (2026)."},"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"145","intvolume":"        15","pmid":1,"month":"03","language":[{"iso":"eng"}],"publisher":"Springer Nature","OA_place":"publisher","article_processing_charge":"No","quality_controlled":"1","publication":"Light: Science & Applications","date_updated":"2026-04-27T07:59:10Z","publication_status":"published","year":"2026","volume":15,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"article_type":"original","oa_version":"Published Version","_id":"21537","abstract":[{"lang":"eng","text":"Nanophotonics has revolutionized the control of light-matter interactions in various fields of fundamental science and technology. In this work, we propose Implosion Fabrication (ImpFab) as a versatile nanophotonics fabrication platform providing the highest spatial resolution, material versatility, and full volumetric control. ImpFab uniquely combines top-down lithography with bottom-up nanoparticle assembly within a hydrogel scaffold, enabling precise control over optical material properties, such as refractive index, by adjusting printing parameters. We showcase the potential of ImpFab by fabricating three-dimensional photonic crystals and quasicrystals, as well as demonstrating optical structures with spatially modulated unit cell material properties. Our results highlight the potential of ImpFab in producing nanostructures with tailored optical functionalities, which are crucial for applications in sensing, imaging, and information processing, and opening new avenues in developing non-Hermitian photonic systems with spatially controlled gain and loss."}],"extern":"1","author":[{"first_name":"Yannick","last_name":"Salamin","full_name":"Salamin, Yannick"},{"full_name":"Yang, Gaojie","first_name":"Gaojie","last_name":"Yang"},{"full_name":"Mills, Brian","last_name":"Mills","first_name":"Brian"},{"first_name":"André","last_name":"Grossi Fonseca","full_name":"Grossi Fonseca, André"},{"last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"first_name":"Quansan","last_name":"Yang","full_name":"Yang, Quansan"},{"last_name":"Beroz","first_name":"Justin","full_name":"Beroz, Justin"},{"full_name":"Kooi, Steven E.","first_name":"Steven E.","last_name":"Kooi"},{"first_name":"Marc","last_name":"de Miguel Comella","full_name":"de Miguel Comella, Marc"},{"last_name":"Mak","first_name":"Kiran","full_name":"Mak, Kiran"},{"full_name":"Vaidya, Sachin","last_name":"Vaidya","first_name":"Sachin"},{"last_name":"Oran","first_name":"Daniel","full_name":"Oran, Daniel"},{"full_name":"Swain, Corban","first_name":"Corban","last_name":"Swain"},{"last_name":"Sun","first_name":"Yi","full_name":"Sun, Yi"},{"full_name":"Maayani, Shai","last_name":"Maayani","first_name":"Shai"},{"full_name":"Sloan, Jamison","first_name":"Jamison","last_name":"Sloan"},{"full_name":"Amin Elfadil Elawad, Amel","last_name":"Amin Elfadil Elawad","first_name":"Amel"},{"last_name":"Lopez","first_name":"Josue J.","full_name":"Lopez, Josue J."},{"full_name":"Boyden, Edward S.","first_name":"Edward S.","last_name":"Boyden"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"external_id":{"pmid":[" 41775693"]}},{"issue":"6","title":"On-chip laser-driven free-electron spin polarizer","OA_type":"hybrid","scopus_import":"1","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"ddc":["530"],"doi":"10.1103/3c1m-d3hh","main_file_link":[{"url":"https://doi.org/10.1103/3c1m-d3hh","open_access":"1"}],"date_created":"2026-03-30T12:22:47Z","status":"public","day":"12","type":"journal_article","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"       136","article_number":"063802","citation":{"short":"C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D.A.B. Miller, O. Solgaard, Physical Review Letters 136 (2026).","apa":"Woodahl, C., Murillo, M., Roques-Carmes, C., Karnieli, A., Miller, D. A. B., &#38; Solgaard, O. (2026). On-chip laser-driven free-electron spin polarizer. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/3c1m-d3hh\">https://doi.org/10.1103/3c1m-d3hh</a>","ista":"Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O. 2026. On-chip laser-driven free-electron spin polarizer. Physical Review Letters. 136(6), 063802.","mla":"Woodahl, Clarisse, et al. “On-Chip Laser-Driven Free-Electron Spin Polarizer.” <i>Physical Review Letters</i>, vol. 136, no. 6, 063802, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/3c1m-d3hh\">10.1103/3c1m-d3hh</a>.","ieee":"C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D. A. B. Miller, and O. Solgaard, “On-chip laser-driven free-electron spin polarizer,” <i>Physical Review Letters</i>, vol. 136, no. 6. American Physical Society, 2026.","chicago":"Woodahl, Clarisse, Melanie Murillo, Charles Roques-Carmes, Aviv Karnieli, David A. B. Miller, and Olav Solgaard. “On-Chip Laser-Driven Free-Electron Spin Polarizer.” <i>Physical Review Letters</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/3c1m-d3hh\">https://doi.org/10.1103/3c1m-d3hh</a>.","ama":"Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O. On-chip laser-driven free-electron spin polarizer. <i>Physical Review Letters</i>. 2026;136(6). doi:<a href=\"https://doi.org/10.1103/3c1m-d3hh\">10.1103/3c1m-d3hh</a>"},"date_published":"2026-02-12T00:00:00Z","quality_controlled":"1","article_processing_charge":"No","publication":"Physical Review Letters","month":"02","OA_place":"publisher","publisher":"American Physical Society","language":[{"iso":"eng"}],"date_updated":"2026-04-27T08:34:51Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","year":"2026","volume":136,"oa_version":"Published Version","_id":"21555","oa":1,"article_type":"original","extern":"1","abstract":[{"text":"Spin-polarized electron beam sources enable studies of spin-dependent electric and magnetic effects at the nanoscale. We propose a method of creating spin-polarized electrons on an integrated photonics chip by laser-driven nanophotonic fields. A two-stage interaction separated by a free-space drift length is proposed, where the first stage and drift length introduces spin-dependent characteristics into the probability distribution of the electron wave function. The second stage uses an adjusted optical near field to rotate the spin states utilizing the spin-dependent wave-packet distribution to produce electrons with high ensemble average spin expectation values. This platform provides an integrated and compact method to generate spin-polarized electrons, implementable with millimeter scale chips and tabletop lasers.","lang":"eng"}],"author":[{"last_name":"Woodahl","first_name":"Clarisse","full_name":"Woodahl, Clarisse"},{"first_name":"Melanie","last_name":"Murillo","full_name":"Murillo, Melanie"},{"last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"last_name":"Karnieli","first_name":"Aviv","full_name":"Karnieli, Aviv"},{"full_name":"Miller, David A. B.","last_name":"Miller","first_name":"David A. B."},{"full_name":"Solgaard, Olav","first_name":"Olav","last_name":"Solgaard"}]},{"language":[{"iso":"eng"}],"publisher":"SPIE","month":"02","author":[{"last_name":"Vaidya","first_name":"Sachin","full_name":"Vaidya, Sachin"},{"full_name":"Choi, Seou","last_name":"Choi","first_name":"Seou"},{"last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"full_name":"Soljačić, Marin","first_name":"Marin","last_name":"Soljačić"}],"publication":"High Contrast Metastructures XV","extern":"1","article_processing_charge":"No","abstract":[{"lang":"eng","text":"We demonstrate that nanophotonic scintillators based on three-dimensional (3D) photonic crystals can overcome the longstanding tradeoff between spatial resolution and light yield in X-ray imaging. By engineering supercollimation, which is light propagation without angular spreading, within the emission spectrum, we strongly shape the angular emission profile of the scintillator, dramatically reducing blurring at large thicknesses. Our theoretical and numerical results, using realistic scintillator and photonic crystal parameters, show that this improves the Detector Quantum Efficiency (DQE) by up to several orders of magnitude at high spatial frequencies, enabling sharper images and reduced X-ray dosages. This approach offers a new path toward high-resolution, low-dose X-ray imaging systems."}],"quality_controlled":"1","conference":{"location":"San Francisco, CA, United States","start_date":"2026-01-17","end_date":"2026-01-23","name":"OPTO"},"date_published":"2026-02-01T00:00:00Z","citation":{"chicago":"Vaidya, Sachin, Seou Choi, Charles Roques-Carmes, and Marin Soljačić. “Supercollimating Photonic Crystal Scintillators.” In <i>High Contrast Metastructures XV</i>, Vol. PC13910. SPIE, 2026. <a href=\"https://doi.org/10.1117/12.3079431\">https://doi.org/10.1117/12.3079431</a>.","ieee":"S. Vaidya, S. Choi, C. Roques-Carmes, and M. Soljačić, “Supercollimating photonic crystal scintillators,” in <i>High Contrast Metastructures XV</i>, San Francisco, CA, United States, 2026, vol. PC13910.","ama":"Vaidya S, Choi S, Roques-Carmes C, Soljačić M. Supercollimating photonic crystal scintillators. In: <i>High Contrast Metastructures XV</i>. Vol PC13910. SPIE; 2026. doi:<a href=\"https://doi.org/10.1117/12.3079431\">10.1117/12.3079431</a>","mla":"Vaidya, Sachin, et al. “Supercollimating Photonic Crystal Scintillators.” <i>High Contrast Metastructures XV</i>, vol. PC13910, PC1391008, SPIE, 2026, doi:<a href=\"https://doi.org/10.1117/12.3079431\">10.1117/12.3079431</a>.","ista":"Vaidya S, Choi S, Roques-Carmes C, Soljačić M. 2026. Supercollimating photonic crystal scintillators. High Contrast Metastructures XV. OPTO vol. PC13910, PC1391008.","apa":"Vaidya, S., Choi, S., Roques-Carmes, C., &#38; Soljačić, M. (2026). Supercollimating photonic crystal scintillators. In <i>High Contrast Metastructures XV</i> (Vol. PC13910). San Francisco, CA, United States: SPIE. <a href=\"https://doi.org/10.1117/12.3079431\">https://doi.org/10.1117/12.3079431</a>","short":"S. Vaidya, S. Choi, C. Roques-Carmes, M. Soljačić, in:, High Contrast Metastructures XV, SPIE, 2026."},"article_number":"PC1391008 ","_id":"21581","oa_version":"None","year":"2026","volume":"PC13910","day":"01","type":"conference","publication_status":"published","status":"public","doi":"10.1117/12.3079431","date_created":"2026-03-30T12:22:48Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-05-05T10:53:00Z","OA_type":"closed access","title":"Supercollimating photonic crystal scintillators"},{"extern":"1","abstract":[{"lang":"eng","text":"Non-Hermiticity naturally arises in physical systems that exchange energy with their environment. The presence of non-Hermiticity leads to many topological physics phenomena and device applications. In the non-Hermitian energy band theory, the foundation of these physics and applications, both energies and wave vectors take complex values. The energy bands thus become a Riemann surface, and such an energy-band Riemann surface underlies all important signatures of non-Hermitian topology. Despite a long history and recent theoretical interests, the energy-band Riemann surface has not been experimentally studied. Here, we provide a photonic observation of the energy-band Riemann surface of a non-Hermitian system. This is achieved by a tunable imaginary gauge transformation in photonic synthetic frequency dimensions. From measured topologies of the Riemann surface, we reveal the complex-energy winding, the open-boundary-condition spectrum, the generalized Brillouin zone, and the branch points. Our findings demonstrate a unified framework in the studies of diverse effects in non-Hermitian topological physics through an experimental observation of energy-band Riemann surfaces."}],"author":[{"full_name":"Cheng, Dali","last_name":"Cheng","first_name":"Dali"},{"last_name":"Wang","first_name":"Heming","full_name":"Wang, Heming"},{"last_name":"Zhong","first_name":"Janet","full_name":"Zhong, Janet"},{"full_name":"Lustig, Eran","last_name":"Lustig","first_name":"Eran"},{"id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes","first_name":"Charles"},{"last_name":"Fan","first_name":"Shanhui","full_name":"Fan, Shanhui"}],"external_id":{"arxiv":["2510.08819"]},"oa_version":"Published Version","_id":"21583","oa":1,"article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","year":"2026","volume":12,"date_updated":"2026-04-27T10:01:35Z","article_processing_charge":"No","quality_controlled":"1","publication":"Science Advances","month":"03","language":[{"iso":"eng"}],"publisher":"American Association for the Advancement of Science","OA_place":"publisher","article_number":"eaec8239","intvolume":"        12","date_published":"2026-03-18T00:00:00Z","citation":{"chicago":"Cheng, Dali, Heming Wang, Janet Zhong, Eran Lustig, Charles Roques-Carmes, and Shanhui Fan. “Experimental Observation of Energy-Band Riemann Surface.” <i>Science Advances</i>. American Association for the Advancement of Science, 2026. <a href=\"https://doi.org/10.1126/sciadv.aec8239\">https://doi.org/10.1126/sciadv.aec8239</a>.","ieee":"D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, and S. Fan, “Experimental observation of energy-band Riemann surface,” <i>Science Advances</i>, vol. 12, no. 12. American Association for the Advancement of Science, 2026.","ama":"Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. Experimental observation of energy-band Riemann surface. <i>Science Advances</i>. 2026;12(12). doi:<a href=\"https://doi.org/10.1126/sciadv.aec8239\">10.1126/sciadv.aec8239</a>","mla":"Cheng, Dali, et al. “Experimental Observation of Energy-Band Riemann Surface.” <i>Science Advances</i>, vol. 12, no. 12, eaec8239, American Association for the Advancement of Science, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aec8239\">10.1126/sciadv.aec8239</a>.","ista":"Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. 2026. Experimental observation of energy-band Riemann surface. Science Advances. 12(12), eaec8239.","apa":"Cheng, D., Wang, H., Zhong, J., Lustig, E., Roques-Carmes, C., &#38; Fan, S. (2026). Experimental observation of energy-band Riemann surface. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.aec8239\">https://doi.org/10.1126/sciadv.aec8239</a>","short":"D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, S. Fan, Science Advances 12 (2026)."},"main_file_link":[{"url":"https://doi.org/10.1126/sciadv.aec8239","open_access":"1"}],"date_created":"2026-03-30T12:22:48Z","doi":"10.1126/sciadv.aec8239","arxiv":1,"status":"public","type":"journal_article","day":"18","DOAJ_listed":"1","OA_type":"gold","issue":"12","title":"Experimental observation of energy-band Riemann surface","scopus_import":"1","publication_identifier":{"issn":["2375-2548"]}},{"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"29:1-29:15","intvolume":"       367","date_published":"2026-05-27T00:00:00Z","citation":{"mla":"Chan, Timothy M., et al. “Charting the Diameter Computation Landscape of Intersection Graphs in 3D and Above.” <i>42nd International Symposium on Computational Geometry</i>, vol. 367, 29:1-29:15, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.29\">10.4230/LIPIcs.SoCG.2026.29</a>.","chicago":"Chan, Timothy M., Hsien Chih Chang, Jie Gao, Sándor Kisfaludi-Bak, Hung Le, and Da Wei Zheng. “Charting the Diameter Computation Landscape of Intersection Graphs in 3D and Above.” In <i>42nd International Symposium on Computational Geometry</i>, Vol. 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.29\">https://doi.org/10.4230/LIPIcs.SoCG.2026.29</a>.","ieee":"T. M. Chan, H. C. Chang, J. Gao, S. Kisfaludi-Bak, H. Le, and D. W. Zheng, “Charting the diameter computation landscape of intersection graphs in 3D and above,” in <i>42nd International Symposium on Computational Geometry</i>, New Brunswick, NJ, United States, 2026, vol. 367.","ama":"Chan TM, Chang HC, Gao J, Kisfaludi-Bak S, Le H, Zheng DW. Charting the diameter computation landscape of intersection graphs in 3D and above. In: <i>42nd International Symposium on Computational Geometry</i>. Vol 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2026. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.29\">10.4230/LIPIcs.SoCG.2026.29</a>","short":"T.M. Chan, H.C. Chang, J. Gao, S. Kisfaludi-Bak, H. Le, D.W. Zheng, in:, 42nd International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026.","ista":"Chan TM, Chang HC, Gao J, Kisfaludi-Bak S, Le H, Zheng DW. 2026. Charting the diameter computation landscape of intersection graphs in 3D and above. 42nd International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 367, 29:1-29:15.","apa":"Chan, T. M., Chang, H. C., Gao, J., Kisfaludi-Bak, S., Le, H., &#38; Zheng, D. W. (2026). Charting the diameter computation landscape of intersection graphs in 3D and above. In <i>42nd International Symposium on Computational Geometry</i> (Vol. 367). New Brunswick, NJ, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.29\">https://doi.org/10.4230/LIPIcs.SoCG.2026.29</a>"},"conference":{"location":"New Brunswick, NJ, United States","start_date":"2026-06-02","end_date":"2026-06-05","name":"SoCG: Symposium on Computational Geometry"},"article_processing_charge":"Yes","quality_controlled":"1","publication":"42nd International Symposium on Computational Geometry","month":"05","language":[{"iso":"eng"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","OA_place":"publisher","OA_type":"gold","title":"Charting the diameter computation landscape of intersection graphs in 3D and above","ddc":["000"],"corr_author":"1","publication_identifier":{"eissn":["1868-8969"],"isbn":["9783959774185"]},"scopus_import":"1","arxiv":1,"date_created":"2026-06-14T22:01:44Z","doi":"10.4230/LIPIcs.SoCG.2026.29","das_tickbox":"0","status":"public","has_accepted_license":"1","type":"conference","day":"27","acknowledgement":"Timothy M. Chan: Supported by NSF grant CCF-2224271.\r\nHsien-Chih Chang: Supported by NSF CAREER award CCF-2443017.\r\nJie Gao: Supported by NSF DMS-2220271, DMS-2311064, IIS-2229876, CCF-2118953, CNS-2515159.\r\nSándor Kisfaludi-Bak: Supported by the Research Council of Finland, Grant 363444.\r\nHung Le: Supported by an NSF grant CCF-2517033 and an NSF CAREER Award CCF-2237288. Da Wei Zheng: This project has received funding from the Austrian Science Fund (FWF) grant\r\nDOI 10.55776/I5982. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","oa_version":"Published Version","project":[{"name":"Static and Dynamic Hierarchical Graph Decompositions","grant_number":"I05982","_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103"}],"_id":"22004","oa":1,"abstract":[{"text":"Recent research on computing the diameter of geometric intersection graphs has made significant strides, primarily focusing on the 2D case [Duraj et al., 2024; Hsien-Chih Chang et al., 2024; Chan et al., 2025] where truly subquadratic-time algorithms were given for simple objects such as unit-disks and (axis-aligned) squares. However, in three or higher dimensions, there is no known truly subquadratic-time algorithm for any intersection graph of non-trivial objects, even basic ones such as unit balls or (axis-aligned) unit cubes. This was partially explained by the pioneering work of Bringmann et al. [Karl Bringmann et al., 2022] which gave several truly subquadratic lower bounds, notably for unit balls or unit cubes in 3D when the graph diameter Δ is at least Ω(log n), hinting at a pessimistic outlook for the complexity of the diameter problem in higher dimensions. In this paper, we substantially extend the landscape of diameter computation for objects in three and higher dimensions, giving a few positive results. Our highlighted findings include:  \r\n1) A truly subquadratic-time algorithm for deciding if the diameter of unit cubes in 3D is at most 3 (Diameter-3 hereafter), the first algorithm of its kind for objects in 3D or higher dimensions. Our algorithm is based on a novel connection to pseudolines, which is of independent interest. \r\n2) A truly subquadratic time lower bound for Diameter-3 of unit balls in 3D under the Orthogonal Vector (OV) hypothesis, giving the first separation between unit balls and unit cubes in the small diameter regime. Previously, computing the diameter for both objects was known to be quadratic hard when the diameter is Ω(log n) [Karl Bringmann et al., 2022]. \r\n3) A near-linear-time algorithm for Diameter-2 of unit cubes in 3D, generalizing the previous result for unit squares in 2D [Karl Bringmann et al., 2022]. \r\n4) A truly subquadratic-time algorithm and lower bound for Diameter-2 and Diameter-3 of rectangular boxes (of arbitrary dimension and sizes), respectively.","lang":"eng"}],"author":[{"full_name":"Chan, Timothy M.","last_name":"Chan","first_name":"Timothy M."},{"full_name":"Chang, Hsien Chih","first_name":"Hsien Chih","last_name":"Chang"},{"full_name":"Gao, Jie","last_name":"Gao","first_name":"Jie"},{"first_name":"Sándor","last_name":"Kisfaludi-Bak","full_name":"Kisfaludi-Bak, Sándor"},{"first_name":"Hung","last_name":"Le","full_name":"Le, Hung"},{"last_name":"Zheng","first_name":"Da Wei","id":"af77956b-e859-11ef-8dc9-d301b898e32f","full_name":"Zheng, Da Wei"}],"external_id":{"arxiv":["2603.21790"]},"department":[{"_id":"MoHe"}],"keyword":["Graph Diameter","Geometric Intersection Graphs","Unit Ball Graphs"],"date_updated":"2026-06-22T08:37:44Z","file_date_updated":"2026-06-22T08:34:11Z","alternative_title":["LIPIcs"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"access_level":"open_access","date_created":"2026-06-22T08:34:11Z","checksum":"ffff03934cc182757d6db82d88f896e6","creator":"dernst","success":1,"file_name":"2026_LIPIcSSoCG_Chan.pdf","content_type":"application/pdf","file_id":"22114","relation":"main_file","date_updated":"2026-06-22T08:34:11Z","file_size":918197}],"publication_status":"published","volume":367,"year":"2026"},{"alternative_title":["LNCS"],"file_date_updated":"2026-06-22T08:18:41Z","date_updated":"2026-06-22T08:21:09Z","keyword":["Signal first-order logic","Robustness-based quantitative semantics","Online runtime monitoring"],"year":"2026","volume":16557,"publication_status":"published","file":[{"file_name":"2026_LNCS_Chalupa.pdf","file_id":"22113","content_type":"application/pdf","relation":"main_file","file_size":849237,"date_updated":"2026-06-22T08:18:41Z","access_level":"open_access","date_created":"2026-06-22T08:18:41Z","checksum":"7055199ecb985e9e2e272f4988827067","creator":"dernst","success":1}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"214-233","oa":1,"_id":"22006","project":[{"name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}],"ec_funded":1,"oa_version":"Published Version","department":[{"_id":"ToHe"}],"author":[{"full_name":"Chalupa, Marek","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463","first_name":"Marek","last_name":"Chalupa"},{"last_name":"Henzinger","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2985-7724","full_name":"Henzinger, Thomas A"},{"last_name":"Sarac","first_name":"Naci E","id":"8C6B42F8-C8E6-11E9-A03A-F2DCE5697425","full_name":"Sarac, Naci E"},{"orcid":"0000-0002-4993-773X","full_name":"Yu, Zhengqi","id":"20aa2ae8-f2f1-11ed-bbfa-8205053f1342","first_name":"Zhengqi","last_name":"Yu"}],"external_id":{"arxiv":["2603.00728"]},"abstract":[{"lang":"eng","text":"Runtime monitoring checks, during execution, whether a partial signal produced by a hybrid system satisfies its specification. Signal First-Order Logic (SFO) offers expressive real-time specifications over such signals, but currently comes only with Boolean semantics and has no tool support. We provide the first robustness-based quantitative semantics for SFO, enabling the expression and evaluation of rich real-time properties beyond the scope of existing formalisms such as Signal Temporal Logic. To enable online monitoring, we identify a past-time fragment of SFO and give a pastification procedure that transforms bounded-response SFO formulas into equisatisfiable formulas in this fragment. We then develop an efficient runtime monitoring algorithm for this past-time fragment and evaluate its performance on a set of benchmarks, demonstrating the practicality and effectiveness of our approach. To the best of our knowledge, this is the first publicly available prototype for online quantitative monitoring of full SFO."}],"ddc":["000"],"scopus_import":"1","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783032262196"]},"OA_type":"hybrid","title":"Quantitative monitoring of Signal First-Order logic","acknowledgement":"We thank the anonymous reviewers for their helpful comments. This work was supported by the European Research Council (ERC) Grants VAMOS (No. 101020093) and HYPER (No. 101055412), and by the Advanced Research and Invention Agency under the Safeguarded AI programme (MSAI-PR01-P047).","day":"18","type":"conference","das_tickbox":"0","status":"public","has_accepted_license":"1","doi":"10.1007/978-3-032-26220-2_11","date_created":"2026-06-14T22:01:44Z","arxiv":1,"conference":{"start_date":"2026-05-18","location":"Tokyo, Japan","end_date":"2026-05-22","name":"FM: Formal Methods"},"date_published":"2026-05-18T00:00:00Z","citation":{"apa":"Chalupa, M., Henzinger, T. A., Sarac, N. E., &#38; Yu, E. (2026). Quantitative monitoring of Signal First-Order logic. In <i>27th International Symposium on Formal Methods</i> (Vol. 16557, pp. 214–233). Tokyo, Japan: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-26220-2_11\">https://doi.org/10.1007/978-3-032-26220-2_11</a>","ista":"Chalupa M, Henzinger TA, Sarac NE, Yu E. 2026. Quantitative monitoring of Signal First-Order logic. 27th International Symposium on Formal Methods. FM: Formal Methods, LNCS, vol. 16557, 214–233.","short":"M. Chalupa, T.A. Henzinger, N.E. Sarac, E. Yu, in:, 27th International Symposium on Formal Methods, Springer Nature, 2026, pp. 214–233.","chicago":"Chalupa, Marek, Thomas A Henzinger, Naci E Sarac, and Emily Yu. “Quantitative Monitoring of Signal First-Order Logic.” In <i>27th International Symposium on Formal Methods</i>, 16557:214–33. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-26220-2_11\">https://doi.org/10.1007/978-3-032-26220-2_11</a>.","ieee":"M. Chalupa, T. A. Henzinger, N. E. Sarac, and E. Yu, “Quantitative monitoring of Signal First-Order logic,” in <i>27th International Symposium on Formal Methods</i>, Tokyo, Japan, 2026, vol. 16557, pp. 214–233.","ama":"Chalupa M, Henzinger TA, Sarac NE, Yu E. Quantitative monitoring of Signal First-Order logic. In: <i>27th International Symposium on Formal Methods</i>. Vol 16557. Springer Nature; 2026:214-233. doi:<a href=\"https://doi.org/10.1007/978-3-032-26220-2_11\">10.1007/978-3-032-26220-2_11</a>","mla":"Chalupa, Marek, et al. “Quantitative Monitoring of Signal First-Order Logic.” <i>27th International Symposium on Formal Methods</i>, vol. 16557, Springer Nature, 2026, pp. 214–33, doi:<a href=\"https://doi.org/10.1007/978-3-032-26220-2_11\">10.1007/978-3-032-26220-2_11</a>."},"intvolume":"     16557","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"OA_place":"publisher","publisher":"Springer Nature","month":"05","publication":"27th International Symposium on Formal Methods","article_processing_charge":"No","quality_controlled":"1"},{"scopus_import":"1","publication_identifier":{"eissn":["1868-8969"],"isbn":["9783959774185"]},"ddc":["500"],"corr_author":"1","title":"Lower bounding the Gromov–Hausdorff distance in metric graphs","OA_type":"gold","type":"conference","day":"27","acknowledgement":"Funding Henry Adams: Simons Foundation Travel Support for Mathematicians.\r\nŽiga Virk: Slovene research agency grant P1-0292.\r\nNicolò Zava: FWF Grant, Project number I4245-N35.\r\n","date_created":"2026-06-14T22:01:44Z","arxiv":1,"doi":"10.4230/LIPIcs.SoCG.2026.3","status":"public","has_accepted_license":"1","das_tickbox":"0","citation":{"short":"H. Adams, S. Majhi, F. Manin, Z. Virk, N. Zava, in:, 42nd International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026.","apa":"Adams, H., Majhi, S., Manin, F., Virk, Z., &#38; Zava, N. (2026). Lower bounding the Gromov–Hausdorff distance in metric graphs. In <i>42nd International Symposium on Computational Geometry</i> (Vol. 367). New Brunswick, NJ, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.3\">https://doi.org/10.4230/LIPIcs.SoCG.2026.3</a>","ista":"Adams H, Majhi S, Manin F, Virk Z, Zava N. 2026. Lower bounding the Gromov–Hausdorff distance in metric graphs. 42nd International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 367, 3:1-3:16.","mla":"Adams, Henry, et al. “Lower Bounding the Gromov–Hausdorff Distance in Metric Graphs.” <i>42nd International Symposium on Computational Geometry</i>, vol. 367, 3:1-3:16, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.3\">10.4230/LIPIcs.SoCG.2026.3</a>.","chicago":"Adams, Henry, Sushovan Majhi, Fedor Manin, Ziga Virk, and Nicolò Zava. “Lower Bounding the Gromov–Hausdorff Distance in Metric Graphs.” In <i>42nd International Symposium on Computational Geometry</i>, Vol. 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.3\">https://doi.org/10.4230/LIPIcs.SoCG.2026.3</a>.","ieee":"H. Adams, S. Majhi, F. Manin, Z. Virk, and N. Zava, “Lower bounding the Gromov–Hausdorff distance in metric graphs,” in <i>42nd International Symposium on Computational Geometry</i>, New Brunswick, NJ, United States, 2026, vol. 367.","ama":"Adams H, Majhi S, Manin F, Virk Z, Zava N. Lower bounding the Gromov–Hausdorff distance in metric graphs. In: <i>42nd International Symposium on Computational Geometry</i>. Vol 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2026. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.3\">10.4230/LIPIcs.SoCG.2026.3</a>"},"date_published":"2026-05-27T00:00:00Z","conference":{"location":"New Brunswick, NJ, United States","start_date":"2026-06-02","name":"SoCG: Symposium on Computational Geometry","end_date":"2026-06-05"},"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"       367","article_number":"3:1-3:16","month":"05","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","OA_place":"publisher","language":[{"iso":"eng"}],"quality_controlled":"1","article_processing_charge":"Yes","publication":"42nd International Symposium on Computational Geometry","file_date_updated":"2026-06-22T08:43:47Z","alternative_title":["LIPIcs"],"keyword":["Gromov–Hausdorff distance","distortion","connectedness","Borsuk–Ulam theorem"],"date_updated":"2026-06-22T08:49:17Z","publication_status":"published","year":"2026","volume":367,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"creator":"dernst","success":1,"date_created":"2026-06-22T08:43:47Z","checksum":"25d27c016409563196b8aecfe5bfdf41","access_level":"open_access","file_size":1091310,"date_updated":"2026-06-22T08:43:47Z","file_id":"22115","content_type":"application/pdf","relation":"main_file","file_name":"2026_LIPIcSSoCG_Adams.pdf"}],"oa":1,"oa_version":"Published Version","_id":"22003","project":[{"_id":"26AD5D90-B435-11E9-9278-68D0E5697425","grant_number":"I04245","call_identifier":"FWF","name":"Algebraic Footprints of Geometric Features in Homology"}],"department":[{"_id":"HeEd"}],"abstract":[{"lang":"eng","text":"Let G be a finite, connected metric graph and let X be a subset of G. If X is sufficiently dense in G, we show that the Gromov-Hausdorff distance matches the Hausdorff distance, namely d_GH(G,X) = d_H(G,X). When the metric graph is the circle G = S¹ with circumference 2π, a recent study established the equality d_GH(S¹,X) = d_H(S¹,X) whenever d_GH(S¹,X) < π/6. Our results relax this hypothesis to d_GH(S¹,X) < π/3, and furthermore, we show that the constant π/3 is the best possible. We lower bound the Gromov-Hausdorff distance d_GH(G,X) by the Hausdorff distance d_H(G,X) via a simple topological obstruction: the existence of a possibly discontinuous function f: G → X with too small distortion contradicts the connectedness of G."}],"external_id":{"arxiv":["2411.09182"]},"author":[{"last_name":"Adams","first_name":"Henry","full_name":"Adams, Henry"},{"first_name":"Sushovan","last_name":"Majhi","full_name":"Majhi, Sushovan"},{"full_name":"Manin, Fedor","last_name":"Manin","first_name":"Fedor"},{"id":"2E36B656-F248-11E8-B48F-1D18A9856A87","full_name":"Virk, Ziga","last_name":"Virk","first_name":"Ziga"},{"orcid":"0000-0001-8686-1888","full_name":"Zava, Nicolò","id":"c8b3499c-7a77-11eb-b046-aa368cbbf2ad","first_name":"Nicolò","last_name":"Zava"}]},{"date_published":"2026-06-01T00:00:00Z","citation":{"apa":"Fei, Q., Fujimoto, S., Naidu, R. P., Chisholm, J., Atek, H., Brammer, G., … Zitrin, A. (2026). A GLIMPSE of intermediate mass Black Holes in the epoch of reionization: Witnessing the descendants of direct collapse? <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae6248\">https://doi.org/10.3847/1538-4357/ae6248</a>","ista":"Fei Q, Fujimoto S, Naidu RP, Chisholm J, Atek H, Brammer G, Asada Y, Berg DA, Bromm V, Furtak LJ, Greene JE, Hsiao TYY, Jeon J, Kokorev V, Matthee JJ, Natarajan P, Pan R, Richard J, Saldana-Lopez A, Schaerer D, Volonteri M, Zitrin A. 2026. A GLIMPSE of intermediate mass Black Holes in the epoch of reionization: Witnessing the descendants of direct collapse? The Astrophysical Journal. 1003(2), 244.","short":"Q. Fei, S. Fujimoto, R.P. Naidu, J. Chisholm, H. Atek, G. Brammer, Y. Asada, D.A. Berg, V. Bromm, L.J. Furtak, J.E. Greene, T.Y.Y. Hsiao, J. Jeon, V. Kokorev, J.J. Matthee, P. Natarajan, R. Pan, J. Richard, A. Saldana-Lopez, D. Schaerer, M. Volonteri, A. Zitrin, The Astrophysical Journal 1003 (2026).","chicago":"Fei, Qinyue, Seiji Fujimoto, Rohan P. Naidu, John Chisholm, Hakim Atek, Gabriel Brammer, Yoshihisa Asada, et al. “A GLIMPSE of Intermediate Mass Black Holes in the Epoch of Reionization: Witnessing the Descendants of Direct Collapse?” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae6248\">https://doi.org/10.3847/1538-4357/ae6248</a>.","ieee":"Q. Fei <i>et al.</i>, “A GLIMPSE of intermediate mass Black Holes in the epoch of reionization: Witnessing the descendants of direct collapse?,” <i>The Astrophysical Journal</i>, vol. 1003, no. 2. IOP Publishing, 2026.","ama":"Fei Q, Fujimoto S, Naidu RP, et al. A GLIMPSE of intermediate mass Black Holes in the epoch of reionization: Witnessing the descendants of direct collapse? <i>The Astrophysical Journal</i>. 2026;1003(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae6248\">10.3847/1538-4357/ae6248</a>","mla":"Fei, Qinyue, et al. “A GLIMPSE of Intermediate Mass Black Holes in the Epoch of Reionization: Witnessing the Descendants of Direct Collapse?” <i>The Astrophysical Journal</i>, vol. 1003, no. 2, 244, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae6248\">10.3847/1538-4357/ae6248</a>."},"dataavailabilitystatement":"10.17909/4byn-fe55 and 10.17909/v2y7-j922 used with Software: LMFIT (M. Newville et al. 2014) msafit (A. de Graaff et al. 2024). - Text extracted from Acknowledgements, no separate DAS","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"244","intvolume":"      1003","month":"06","language":[{"iso":"eng"}],"OA_place":"publisher","publisher":"IOP Publishing","article_processing_charge":"Yes","quality_controlled":"1","publication":"The Astrophysical Journal","ddc":["520"],"scopus_import":"1","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"OA_type":"gold","supplementarymaterial":"yes","title":"A GLIMPSE of intermediate mass Black Holes in the epoch of reionization: Witnessing the descendants of direct collapse?","issue":"2","day":"01","type":"journal_article","DOAJ_listed":"1","acknowledgement":"We thank the anonymous referee for insightful comments, which significantly improved the manuscript. We acknowledge Kohei Inayoshi for helpful discussions. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. The specific observations analyzed can be accessed via DOI: 10.17909/4byn-fe55 and 10.17909/v2y7-j922. These observations are associated with programs #3293 and #9223. S.F. and Q.F. acknowledge support from the Dunlap Institute, which is funded through an endowment established by the David Dunlap family and the University of Toronto. A.S.L. acknowledges support from the Knut and Alice Wallenberg Foundation. A.Z. acknowledges support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF); and by the Israel Science Foundation grant No. 864/23.","date_created":"2026-06-14T22:01:43Z","arxiv":1,"doi":"10.3847/1538-4357/ae6248","das_tickbox":"0","status":"public","has_accepted_license":"1","oa":1,"article_type":"original","oa_version":"Published Version","_id":"21999","department":[{"_id":"JoMa"}],"PlanS_conform":"1","abstract":[{"text":"JWST has revealed an abundance of supermassive black holes (BHs) in the early Universe, and yet the lowest mass seed BHs that gave rise to these populations remain elusive. Here, we present a systematic search for broad-line active galactic nuclei (AGNs) in some of the faintest high-z galaxies surveyed yet by combining ultra-deep JWST/NIRSpec G395M spectroscopy with the strong lensing aid in AS1063. By employing the profile of the [O iii]λ5007 emission lines as a template for narrow-line components and carefully cross-validating with mock observations, we identify a sample of 10 broad-line AGNs at 4.5 < z < 7.0 (eight secure, two tentative). The inferred BH masses from the broad Hα line explore the intermediate BH mass regime down to ∼105.5 M⊙. The stellar mass (M*) is estimated with a galaxy+AGN composite model, and we find the BH to stellar mass ratio spans down to MBH/M* ≲ 0.1%, unveiling populations on the empirical MBH–M* relation observed in the local Universe. We also derive the BH mass function and investigate its low-mass end at this epoch. While we confirm the agreement of our results with previous studies at MBH ≳ 106.5M⊙, we find the mass range of ∼105.5 M⊙ features an enhanced abundance with respect to the extrapolated best-fit Schechter function. Comparison with theoretical models suggests that a possible origin for this enhanced abundance is the direct-collapse BH formation, supporting the scenario that the direct collapse of massive gas clouds is a significant pathway for the earliest supermassive BHs.","lang":"eng"}],"researchdata_availability":"yes","author":[{"last_name":"Fei","first_name":"Qinyue","full_name":"Fei, Qinyue"},{"last_name":"Fujimoto","first_name":"Seiji","full_name":"Fujimoto, Seiji"},{"full_name":"Naidu, Rohan P.","first_name":"Rohan P.","last_name":"Naidu"},{"first_name":"John","last_name":"Chisholm","full_name":"Chisholm, John"},{"full_name":"Atek, Hakim","last_name":"Atek","first_name":"Hakim"},{"first_name":"Gabriel","last_name":"Brammer","full_name":"Brammer, Gabriel"},{"last_name":"Asada","first_name":"Yoshihisa","full_name":"Asada, Yoshihisa"},{"full_name":"Berg, Danielle A.","first_name":"Danielle A.","last_name":"Berg"},{"full_name":"Bromm, Volker","first_name":"Volker","last_name":"Bromm"},{"full_name":"Furtak, Lukas J.","first_name":"Lukas J.","last_name":"Furtak"},{"full_name":"Greene, Jenny E.","first_name":"Jenny E.","last_name":"Greene"},{"full_name":"Hsiao, Tiger Yu Yang","last_name":"Hsiao","first_name":"Tiger Yu Yang"},{"first_name":"Junehyoung","last_name":"Jeon","full_name":"Jeon, Junehyoung"},{"full_name":"Kokorev, Vasily","last_name":"Kokorev","first_name":"Vasily"},{"full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee"},{"full_name":"Natarajan, Priyamvada","first_name":"Priyamvada","last_name":"Natarajan"},{"last_name":"Pan","first_name":"Richard","full_name":"Pan, Richard"},{"full_name":"Richard, Johan","last_name":"Richard","first_name":"Johan"},{"last_name":"Saldana-Lopez","first_name":"Alberto","full_name":"Saldana-Lopez, Alberto"},{"last_name":"Schaerer","first_name":"Daniel","full_name":"Schaerer, Daniel"},{"last_name":"Volonteri","first_name":"Marta","full_name":"Volonteri, Marta"},{"first_name":"Adi","last_name":"Zitrin","full_name":"Zitrin, Adi"}],"external_id":{"arxiv":["2509.20452"]},"file_date_updated":"2026-06-22T08:03:55Z","date_updated":"2026-06-22T11:34:52Z","publication_status":"published","year":"2026","volume":1003,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_name":"2026_AstrophysicalJour_Fei.pdf","relation":"main_file","file_id":"22112","content_type":"application/pdf","file_size":19681834,"date_updated":"2026-06-22T08:03:55Z","access_level":"open_access","checksum":"b04247996b8dcd0eb5387581706d1106","date_created":"2026-06-22T08:03:55Z","success":1,"creator":"dernst"}]},{"quality_controlled":"1","article_processing_charge":"Yes","publication":"42nd International Symposium on Computational Geometry","month":"05","OA_place":"publisher","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","language":[{"iso":"eng"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_number":"93:1-93:22","intvolume":"       367","citation":{"mla":"Tinarrage, Raphaël. “Simplicial Approximation to CW Complexes with Spherical Delaunay Triangulations.” <i>42nd International Symposium on Computational Geometry</i>, vol. 367, 93:1-93:22, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.93\">10.4230/LIPIcs.SoCG.2026.93</a>.","chicago":"Tinarrage, Raphaël. “Simplicial Approximation to CW Complexes with Spherical Delaunay Triangulations.” In <i>42nd International Symposium on Computational Geometry</i>, Vol. 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.93\">https://doi.org/10.4230/LIPIcs.SoCG.2026.93</a>.","ieee":"R. Tinarrage, “Simplicial approximation to CW complexes with spherical Delaunay triangulations,” in <i>42nd International Symposium on Computational Geometry</i>, New Brunswick, NJ, United States, 2026, vol. 367.","ama":"Tinarrage R. Simplicial approximation to CW complexes with spherical Delaunay triangulations. In: <i>42nd International Symposium on Computational Geometry</i>. Vol 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2026. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.93\">10.4230/LIPIcs.SoCG.2026.93</a>","short":"R. Tinarrage, in:, 42nd International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026.","ista":"Tinarrage R. 2026. Simplicial approximation to CW complexes with spherical Delaunay triangulations. 42nd International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry vol. 367, 93:1-93:22.","apa":"Tinarrage, R. (2026). Simplicial approximation to CW complexes with spherical Delaunay triangulations. In <i>42nd International Symposium on Computational Geometry</i> (Vol. 367). New Brunswick, NJ, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.93\">https://doi.org/10.4230/LIPIcs.SoCG.2026.93</a>"},"date_published":"2026-05-27T00:00:00Z","conference":{"start_date":"2026-06-02","location":"New Brunswick, NJ, United States","end_date":"2026-06-05","name":"SoCG: Symposium on Computational Geometry"},"date_created":"2026-06-14T22:01:43Z","arxiv":1,"doi":"10.4230/LIPIcs.SoCG.2026.93","status":"public","has_accepted_license":"1","das_tickbox":"0","day":"27","type":"conference","supplementarymaterial":"yes","title":"Simplicial approximation to CW complexes with spherical Delaunay triangulations","OA_type":"gold","publication_identifier":{"isbn":["9783959774185"],"eissn":["1868-8969"]},"scopus_import":"1","ddc":["500"],"corr_author":"1","researchdata_availability":"no","abstract":[{"lang":"eng","text":"Simplicial approximation provides a framework for constructing simplicial complexes that are homotopy equivalent to a given manifold, provided a CW structure is explicitly known. However, its conventional implementation quickly becomes intractable on a computer: barycentric subdivision produces poorly shaped simplices, and the star condition introduces many vertices. To address these limitations, this article develops a subdivision scheme based on spherical Delaunay triangulations, which attains better refinement properties than barycentric subdivisions. Moreover, the star condition is reframed as two independent problems, one geometric and the other combinatorial, respectively tackled in the language of locally equiconnected spaces and the list homomorphism problem, allowing an exponential reduction in the number of vertices. Via a prototype implementation, we obtain simplicial complexes homotopy equivalent to Grassmannians and Stiefel manifolds up to dimension 5."}],"external_id":{"arxiv":["2112.07573"]},"author":[{"last_name":"Tinarrage","first_name":"Raphaël","id":"40ebcc9d-905f-11ef-bf0a-dc475da8a04e","full_name":"Tinarrage, Raphaël","orcid":"0000-0002-1404-1095"}],"department":[{"_id":"UlWa"}],"oa_version":"Published Version","_id":"22000","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","related_material":{"link":[{"url":"https://doi.org/10.5281/zenodo.19251455","relation":"software"}]},"file":[{"access_level":"open_access","checksum":"a468edad327962309688aa78678138da","date_created":"2026-06-22T07:53:13Z","success":1,"creator":"dernst","file_name":"2026_LIPIcSSoCG_Tinarrage.pdf","relation":"main_file","file_id":"22111","content_type":"application/pdf","date_updated":"2026-06-22T07:53:13Z","file_size":1436035}],"publication_status":"published","volume":367,"year":"2026","keyword":["Triangulation of manifolds","Simplicial approximation","CW complexes","Delaunay complexes","List homomorphism problem","Topological Data Analysis"],"date_updated":"2026-06-22T11:28:26Z","file_date_updated":"2026-06-22T07:53:13Z"}]