[{"language":[{"iso":"eng"}],"date_updated":"2026-06-08T07:42:16Z","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.gde.2026.102487"}],"_id":"21948","date_published":"2026-05-29T00:00:00Z","month":"05","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["570"],"year":"2026","corr_author":"1","PlanS_conform":"1","status":"public","title":"Tracing cell lineages in the developing brain: Insights from mosaic analysis and clone-resolved transcriptomics","volume":99,"oa_version":"Published Version","pmid":1,"publication_identifier":{"eissn":["1879-0380"],"issn":["0959-437X"]},"doi":"10.1016/j.gde.2026.102487","abstract":[{"lang":"eng","text":"The cerebral cortex comprises diverse neuron and glial cell types generated by radial glial progenitors (RGPs) during development. Although RGPs broadly differentiate according to temporally and spatially regulated molecular logics, the lineage hierarchies linking individual progenitors to defined cell (sub)types are not well understood. Clone-resolved transcriptomics, combining molecular barcoding and single-cell RNA sequencing, allow high-resolution lineage tracing at the single-clone/cell level across different species and models. In this mini-review, we synthesize recent advances in this field, uncovering unexpected lineage relationships in the developing brain, with a particular focus on the cerebral cortex. We further highlight new insights into species-specific differences in the developmental programs generating cell-type diversity, linking changes in clonal architecture to lineage diversification during cortical evolution."}],"publication":"Current Opinion in Genetics and Development","publication_status":"epub_ahead","publisher":"Elsevier","article_type":"original","date_created":"2026-06-07T22:01:35Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes (via OA deal)","type":"journal_article","oa":1,"citation":{"ista":"Varela Martínez I, Pipicelli F, Hippenmeyer S. 2026. Tracing cell lineages in the developing brain: Insights from mosaic analysis and clone-resolved transcriptomics. Current Opinion in Genetics and Development. 99, 102487.","apa":"Varela Martínez, I., Pipicelli, F., &#38; Hippenmeyer, S. (2026). Tracing cell lineages in the developing brain: Insights from mosaic analysis and clone-resolved transcriptomics. <i>Current Opinion in Genetics and Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2026.102487\">https://doi.org/10.1016/j.gde.2026.102487</a>","mla":"Varela Martínez, Irene, et al. “Tracing Cell Lineages in the Developing Brain: Insights from Mosaic Analysis and Clone-Resolved Transcriptomics.” <i>Current Opinion in Genetics and Development</i>, vol. 99, 102487, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102487\">10.1016/j.gde.2026.102487</a>.","ieee":"I. Varela Martínez, F. Pipicelli, and S. Hippenmeyer, “Tracing cell lineages in the developing brain: Insights from mosaic analysis and clone-resolved transcriptomics,” <i>Current Opinion in Genetics and Development</i>, vol. 99. Elsevier, 2026.","ama":"Varela Martínez I, Pipicelli F, Hippenmeyer S. Tracing cell lineages in the developing brain: Insights from mosaic analysis and clone-resolved transcriptomics. <i>Current Opinion in Genetics and Development</i>. 2026;99. doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102487\">10.1016/j.gde.2026.102487</a>","short":"I. Varela Martínez, F. Pipicelli, S. Hippenmeyer, Current Opinion in Genetics and Development 99 (2026).","chicago":"Varela Martínez, Irene, Fabrizia Pipicelli, and Simon Hippenmeyer. “Tracing Cell Lineages in the Developing Brain: Insights from Mosaic Analysis and Clone-Resolved Transcriptomics.” <i>Current Opinion in Genetics and Development</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.gde.2026.102487\">https://doi.org/10.1016/j.gde.2026.102487</a>."},"day":"29","OA_place":"publisher","intvolume":"        99","scopus_import":"1","article_number":"102487","external_id":{"pmid":["42214837"]},"OA_type":"hybrid","author":[{"id":"a69b5985-8829-11f0-8fc2-d0af58f64471","first_name":"Irene","full_name":"Varela Martínez, Irene","last_name":"Varela Martínez"},{"first_name":"Fabrizia","id":"649134fd-d012-11ed-8f82-db1e5050f9ba","last_name":"Pipicelli","full_name":"Pipicelli, Fabrizia"},{"orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon"}],"project":[{"grant_number":"ALTF 994-2023","_id":"7c084566-9f16-11ee-852c-c88a1dbbf1cf","name":"Role of cell lineage in generating cell-type diversity in developing neocortex’"},{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression"}],"acknowledgement":"We wish to thank all members of the Hippenmeyer laboratory at ISTA for exciting discussions on the subject of this review. We apologize to colleagues whose work we could not cite and/or discuss in the frame of the available space. Work in the Hippenmeyer laboratory on the discussed topic is supported by ISTA institutional funds, an EMBO LTF (ALTF 994–2023) to F.P., FWF SFB F78 (10.55776/F78) to S.H., and FWF Cluster of Excellence COE16 (10.55776/COE16) to S.H.","department":[{"_id":"SiHi"}]},{"title":"T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration","volume":315,"page":"1969-1982","corr_author":"1","status":"public","related_material":{"link":[{"url":"https://github.com/tamirshor7/T1-PILOT","relation":"software"}]},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","month":"03","conference":{"end_date":"2026-07-10","name":"MIDL: Medical Imaging with Deep Learning","start_date":"2026-07-08","location":"Taipei, Taiwan"},"ddc":["000"],"year":"2026","language":[{"iso":"eng"}],"date_updated":"2026-06-08T08:05:24Z","quality_controlled":"1","alternative_title":["PMLR"],"date_published":"2026-03-17T00:00:00Z","_id":"21949","main_file_link":[{"open_access":"1","url":"https://openreview.net/forum?id=nZaPtHbd6N#discussion"}],"scopus_import":"1","author":[{"last_name":"Shor","full_name":"Shor, Tamir","first_name":"Tamir"},{"first_name":"Moti","last_name":"Freiman","full_name":"Freiman, Moti"},{"first_name":"Chaim","last_name":"Baskin","full_name":"Baskin, Chaim"},{"full_name":"Bronstein, Alexander","last_name":"Bronstein","orcid":"0000-0001-9699-8730","first_name":"Alexander","id":"58f3726e-7cba-11ef-ad8b-e6e8cb3904e6"}],"OA_type":"gold","department":[{"_id":"AlBr"}],"oa":1,"article_processing_charge":"No","type":"conference","citation":{"ieee":"T. Shor, M. Freiman, C. Baskin, and A. M. Bronstein, “T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration,” in <i>Medical Imaging with Deep Learning</i>, Taipei, Taiwan, vol. 315, pp. 1969–1982.","ista":"Shor T, Freiman M, Baskin C, Bronstein AM. T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. Medical Imaging with Deep Learning. MIDL: Medical Imaging with Deep Learning, PMLR, vol. 315, 1969–1982.","apa":"Shor, T., Freiman, M., Baskin, C., &#38; Bronstein, A. M. (n.d.). T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. In <i>Medical Imaging with Deep Learning</i> (Vol. 315, pp. 1969–1982). Taipei, Taiwan: ML Research Press.","mla":"Shor, Tamir, et al. “T1-PILOT: Physics-Informed Learned Optimized Trajectories for T1 Mapping Acceleration.” <i>Medical Imaging with Deep Learning</i>, vol. 315, ML Research Press, pp. 1969–82.","chicago":"Shor, Tamir, Moti Freiman, Chaim Baskin, and Alex M. Bronstein. “T1-PILOT: Physics-Informed Learned Optimized Trajectories for T1 Mapping Acceleration.” In <i>Medical Imaging with Deep Learning</i>, 315:1969–82. ML Research Press, n.d.","ama":"Shor T, Freiman M, Baskin C, Bronstein AM. T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. In: <i>Medical Imaging with Deep Learning</i>. Vol 315. ML Research Press; :1969-1982.","short":"T. Shor, M. Freiman, C. Baskin, A.M. Bronstein, in:, Medical Imaging with Deep Learning, ML Research Press, n.d., pp. 1969–1982."},"keyword":["Cardiac T1 Mapping","Trajectory Optimization and Reconstruction","PhysicsInformed Deep-Learning"],"OA_place":"publisher","day":"17","intvolume":"       315","publisher":"ML Research Press","date_created":"2026-06-07T22:01:36Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","publication_identifier":{"eissn":["2640-3498"]},"publication_status":"accepted","abstract":[{"lang":"eng","text":"Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema.\r\nHowever, the inherently dynamic nature of the heart imposes strict limits on acquisition\r\ntimes, making high-resolution T1 mapping a persistent challenge. Compressed sensing (CS)\r\napproaches have reduced scan durations by undersampling k-space and reconstructing images from partial data, and recent studies show that jointly optimizing the undersampling\r\npatterns with the reconstruction network can substantially improve performance. Still,\r\nmost current T1 mapping pipelines rely on static, hand-crafted masks that do not exploit\r\nthe full acceleration and accuracy potential. Furthermore, most existing methods do not\r\nlevarage the physical T1 decay model in optimization. In this work, we introduce T1-\r\nPILOT: an end-to-end method that explicitly incorporates the T1 signal relaxation model\r\ninto the sampling–reconstruction framework to guide the learning of non-Cartesian trajectories, cross-frame alignment, and T1 decay estimation. Through extensive experiments\r\non the CMRxRecon dataset, T1-PILOT significantly outperforms several baseline strategies (including learned single-mask and fixed radial or golden-angle sampling schemes),\r\nachieving higher T1 map fidelity at greater acceleration factors. In particular, we observe consistent gains in PSNR and VIF relative to existing methods, along with marked\r\nimprovements in delineating finer myocardial structures. Our results highlight that optimizing sampling trajectories in tandem with the physical relaxation model leads to both\r\nenhanced quantitative accuracy and reduced acquisition times. Code for reproducing all\r\nexperiments and results is available at https://github.com/tamirshor7/T1-PILOT"}],"publication":"Medical Imaging with Deep Learning"},{"date_created":"2026-06-07T22:01:36Z","month":"01","article_type":"original","publisher":"SAGE Publications","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","publication_identifier":{"issn":["0261-1929"],"eissn":["2632-3559"]},"oa_version":"None","quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-06-08T08:13:29Z","publication_status":"epub_ahead","date_published":"2026-01-01T00:00:00Z","_id":"21950","publication":"Alternatives to Laboratory Animals","abstract":[{"lang":"eng","text":"One Health initiatives are modern paradigms for research and health care practices in various fields. Concrete definitions of the One Health framework, however, remain heterogeneous, leading to conceptual problems and uncertainties in the application of the framework. This article discusses several approaches to the One Health concept, and their associated consequences, with special focus on animal experimentation. The first issue addressed is how One Health should be defined, as well as what (and who) should be considered within a One Health approach. In order to shed further light on this, we explore the history of animals in biomedical science, highlighting historical milestones in the use of animal models, as well as the development and current state of ethical considerations in the field of animal experimentation. The second issue comes with the inclusion of animal experimentation per se as part of the One Health concept. Therefore, particular attention is paid to bioethical principles and the resulting problems that can arise when applying them to the One Health concept. Arguments such as the idea of inequality between humans and non-human animals, and the premise that all actions are done for the benefit of humans, are raised and then used to explore the question of whether the One Health concept is compatible with existing bioethical principles. Based on the bioethical principles of protecting the environment, the biodiversity and biosphere, this paper seeks an inclusive perspective of the One Health concept. Successful solutions will be based on this concept, which embraces all living beings. The authors conclude that a multispecies ethics approach could help create a more ethical ecosystem that is aligned with the wellbeing of all life on a shared planet."}],"doi":"10.1177/02611929261453330","author":[{"first_name":"Yesim Isil","last_name":"Ulman","full_name":"Ulman, Yesim Isil"},{"full_name":"Kostomitsopoulos, Nikos","last_name":"Kostomitsopoulos","first_name":"Nikos"},{"first_name":"Samuel","full_name":"Camenzind, Samuel","last_name":"Camenzind"},{"last_name":"Kitsara","full_name":"Kitsara, Maria","first_name":"Maria"},{"full_name":"Pavone, Ilja Richard","last_name":"Pavone","first_name":"Ilja Richard"},{"last_name":"Schober","full_name":"Schober, Sophie","id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8","first_name":"Sophie"}],"OA_type":"closed access","title":"Emerging bioethical conflicts: One Health and animal experimentation","scopus_import":"1","department":[{"_id":"PreCl"}],"citation":{"chicago":"Ulman, Yesim Isil, Nikos Kostomitsopoulos, Samuel Camenzind, Maria Kitsara, Ilja Richard Pavone, and Sophie Schober. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” <i>Alternatives to Laboratory Animals</i>. SAGE Publications, 2026. <a href=\"https://doi.org/10.1177/02611929261453330\">https://doi.org/10.1177/02611929261453330</a>.","short":"Y.I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I.R. Pavone, S. Schober, Alternatives to Laboratory Animals (2026).","ama":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. Emerging bioethical conflicts: One Health and animal experimentation. <i>Alternatives to Laboratory Animals</i>. 2026. doi:<a href=\"https://doi.org/10.1177/02611929261453330\">10.1177/02611929261453330</a>","ieee":"Y. I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I. R. Pavone, and S. Schober, “Emerging bioethical conflicts: One Health and animal experimentation,” <i>Alternatives to Laboratory Animals</i>. SAGE Publications, 2026.","ista":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. 2026. Emerging bioethical conflicts: One Health and animal experimentation. Alternatives to Laboratory Animals.","apa":"Ulman, Y. I., Kostomitsopoulos, N., Camenzind, S., Kitsara, M., Pavone, I. R., &#38; Schober, S. (2026). Emerging bioethical conflicts: One Health and animal experimentation. <i>Alternatives to Laboratory Animals</i>. SAGE Publications. <a href=\"https://doi.org/10.1177/02611929261453330\">https://doi.org/10.1177/02611929261453330</a>","mla":"Ulman, Yesim Isil, et al. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” <i>Alternatives to Laboratory Animals</i>, SAGE Publications, 2026, doi:<a href=\"https://doi.org/10.1177/02611929261453330\">10.1177/02611929261453330</a>."},"corr_author":"1","article_processing_charge":"No","type":"journal_article","status":"public","day":"01"},{"date_published":"2026-05-25T00:00:00Z","_id":"21951","quality_controlled":"1","date_updated":"2026-06-08T08:25:40Z","language":[{"iso":"eng"}],"ddc":["520"],"year":"2026","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","month":"05","status":"public","PlanS_conform":"1","arxiv":1,"volume":9,"title":"Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot","publication_status":"published","publication":"The Open Journal of Astrophysics","abstract":[{"lang":"eng","text":"The central engines of Little Red Dots (LRDs) may be “black hole stars” (BH*s), early stages of\r\nblack hole growth characterized by dense gas envelopes. So far, the most direct evidence for BH*s\r\ncomes from a handful of sources where the host galaxy is completely outshone as suggested by their\r\nremarkably steep Balmer breaks. Here we present a novel scheme to disentangle BH*s from their\r\nhost galaxies assuming that the [O III]5008˚A line arises exclusively from the host. Using a sample\r\nof 98 LRDs (z ≈ 2 − 9) with high quality NIRSpec/PRISM spectra, we demonstrate that the hostsubtracted median stack displays a Balmer break > 2× stronger than massive quiescent galaxies,\r\nwith the rest-optical continuum resembling a blackbody-like SED (Teff ≈ 4050 K, log(Lbol) ≈ 43.9\r\nerg s−1\r\n, Reff ≈ 1300 au). We measure a steep Balmer decrement (Hα/Hβ > 10) and numerous\r\ndensity-sensitive features (e.g., Fe II, He I, O I). These are hallmark signatures of dense gas envelopes,\r\nproviding population-level evidence that BH*s indeed power LRDs. In the median LRD, BH*s account\r\nfor ∼ 20% of the UV emission, ∼ 50% at the Balmer break, and ∼ 90% at wavelengths longer\r\nthan Hα with the remainder arising from the host. BH*s preferentially reside in low-mass galaxies\r\n(M⋆ ≈ 108 M⊙) undergoing recent starbursts, as evidenced by extreme emission line EWs (e.g.,\r\n[O III]5008˚A≈ 1100˚A, C III]≈ 12˚A), thereby favoring BH* origins linked to star-formation. We show\r\nV-shaped LRD selections are biased to high BH*/host fractions (≳ 60% at 5500˚A) – less dominant\r\nBH*s may be powering JWST’s blue broad-line AGN. We find BH*s are so commonplace and transient\r\n(duty cycle ∼ 1%, lifetime ∼ 10 Myrs) that every massive black hole may have once shone as a BH*.\r\n"}],"file":[{"checksum":"33c4a444f7c37b3f47ecbd53eb187c1b","file_name":"2026_OpenJourAstrophysics_Sun.pdf","success":1,"creator":"dernst","file_id":"21952","date_updated":"2026-06-08T08:23:37Z","file_size":7591188,"date_created":"2026-06-08T08:23:37Z","relation":"main_file","content_type":"application/pdf","access_level":"open_access"}],"doi":"10.33232/001c.162505","DOAJ_listed":"1","oa_version":"Published Version","publication_identifier":{"eissn":["2565-6120"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-06-07T22:01:36Z","article_type":"original","publisher":"Maynooth Academic Publishing","intvolume":"         9","OA_place":"publisher","file_date_updated":"2026-06-08T08:23:37Z","day":"25","citation":{"ieee":"W. Q. Sun <i>et al.</i>, “Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot,” <i>The Open Journal of Astrophysics</i>, vol. 9. Maynooth Academic Publishing, 2026.","ista":"Sun WQ, Naidu RP, Matthee JJ, De Graaff A, Chisholm J, Greene JE, Oesch PA, Torralba Torregrosa A, Hviding RE, Brammer G, Simcoe RA, Bose S, Bouwens R, Dayal P, Eilers AC, Fei Q, Furtak LJ, Gottumukkala R, Goulding A, Heintz KE, Hirschmann M, Kokorev V, Leja J, Liu Z, Natarajan P, Santarelli AD, Setton DJ, Smith A, Tacchella S, Volonteri M, Walter F, Weibel A, Williams CC. 2026. Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. The Open Journal of Astrophysics. 9.","apa":"Sun, W. Q., Naidu, R. P., Matthee, J. J., De Graaff, A., Chisholm, J., Greene, J. E., … Williams, C. C. (2026). Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing. <a href=\"https://doi.org/10.33232/001c.162505\">https://doi.org/10.33232/001c.162505</a>","mla":"Sun, Wendy Q., et al. “Little Red Dot - Host Galaxy = Black Hole Star: A Gas-Enshrouded Heart at the Center of Every Little Red Dot.” <i>The Open Journal of Astrophysics</i>, vol. 9, Maynooth Academic Publishing, 2026, doi:<a href=\"https://doi.org/10.33232/001c.162505\">10.33232/001c.162505</a>.","chicago":"Sun, Wendy Q., Rohan P. Naidu, Jorryt J Matthee, Anna De Graaff, John Chisholm, Jenny E. Greene, Pascal A. Oesch, et al. “Little Red Dot - Host Galaxy = Black Hole Star: A Gas-Enshrouded Heart at the Center of Every Little Red Dot.” <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing, 2026. <a href=\"https://doi.org/10.33232/001c.162505\">https://doi.org/10.33232/001c.162505</a>.","short":"W.Q. Sun, R.P. Naidu, J.J. Matthee, A. De Graaff, J. Chisholm, J.E. Greene, P.A. Oesch, A. Torralba Torregrosa, R.E. Hviding, G. Brammer, R.A. Simcoe, S. Bose, R. Bouwens, P. Dayal, A.C. Eilers, Q. Fei, L.J. Furtak, R. Gottumukkala, A. Goulding, K.E. Heintz, M. Hirschmann, V. Kokorev, J. Leja, Z. Liu, P. Natarajan, A.D. Santarelli, D.J. Setton, A. Smith, S. Tacchella, M. Volonteri, F. Walter, A. Weibel, C.C. Williams, The Open Journal of Astrophysics 9 (2026).","ama":"Sun WQ, Naidu RP, Matthee JJ, et al. Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. <i>The Open Journal of Astrophysics</i>. 2026;9. doi:<a href=\"https://doi.org/10.33232/001c.162505\">10.33232/001c.162505</a>"},"oa":1,"type":"journal_article","article_processing_charge":"No","acknowledgement":"We thank the two anonymous referees for their insightful comments that have strengthened this work.\r\nWQS and RPN acknowledge funding from JWST programs GO-3516, GO-5224, and the MIT Undergraduate\r\nResearch Opportunities Program (UROP). Support for\r\nthis work was provided by NASA through the NASA\r\nHubble Fellowship grant HST-HF2-51515.001-A awarded\r\nby the Space Telescope Science Institute, which is operated by the Association of Universities for Research in\r\nAstronomy, Incorporated, under NASA contract NAS5-\r\n26555. RPN thanks Neil Pappalardo and Jane Pappalardo for their generous support of the MIT Pappalardo Fellowships in Physics, and for their enthusiasm\r\nand encouragement for pursuing the earliest galaxies and\r\nblack holes. JM and AT acknowledge funding from the\r\nEuropean Union (ERC, AGENTS, 101076224). KEH\r\nacknowledges support from the Independent Research Fund Denmark (DFF) under grant 5251-00009B and cofunding by the European Union (ERC, HEAVYMETAL,\r\n101071865). Views and opinions expressed are, however,\r\nthose of the authors only and do not necessarily reflect\r\nthose of the European Union or the European Research\r\nCouncil. Neither the European Union nor the granting\r\nauthority can be held responsible for them. REH acknowledges support by the German Aerospace Center\r\n(DLR) and the Federal Ministry for Economic Affairs\r\nand Energy (BMWi) through program 50OR2403 ‘RUBIES’.\r\nThe data products presented herein were retrieved\r\nfrom the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is\r\nfunded by the Danish National Research Foundation under grant DNRF140. This work is based on observations\r\nmade with the NASA/ESA/CSA James Webb Space\r\nTelescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope\r\nScience Institute, which is operated by the Association\r\nof Universities for Research in Astronomy, Inc., under\r\nNASA contract NAS 5-03127 for JWST. Support for\r\nprograms #3516, #5224, #5664 was provided by NASA\r\nthrough grants from the Space Telescope Science Institute, which is operated by the Association of Universities\r\nfor Research in Astronomy, Inc., under NASA contract\r\nNAS 5-03127.\r\nThe spectra used in this paper are associated with programs 1180 (D’Eugenio et al. 2025d), 1181 (PI: D. Eisenstein), 1208 (Willott et al. 2022), 1210 (PI: N. Luetzgendorf), 1211 (Maseda et al. 2024), 1212 - 1215 (PI: N.\r\nLuetzgendorf), 1228 (Luhman et al. 2024b), 1229 (Luhman et al. 2024a), 1286 (PI: N. Luetzgendorf), 1287 (PI:\r\nK. Isaak), 1345 (Finkelstein et al. 2023), 1433 (Hsiao\r\net al. 2024), 1747 (PI: G. Roberts-Borsani), 2028 (Wang\r\net al. 2024c), 2073 (PI: J. Hennawi), 2198 (Barrufet\r\net al. 2025), 2282 (Bradley et al. 2023), 2561 (Bezanson\r\net al. 2024), 2565 (Nanayakkara et al. 2025), 2640 (PI:\r\nW. Best), 2750 (Arrabal Haro et al. 2023), 2756 (Mascia et al. 2024), 2767 (Williams et al. 2023b), 2770 (PI:\r\nM. McCaughrean), 3073 (Castellano et al. 2024), 3215\r\n(Eisenstein et al. 2025), 4106 (PI: E. Nelson), 4233 (de\r\nGraaff et al. 2025c), 4446 (Frye et al. 2024), 4557 (PI: H.\r\nYan), 5105 (Shen et al. 2024), 5224 (PIs: P.A. Oesch &\r\nR.P. Naidu), 6368 (PI: M. Dickinson), 6541 (DeCoursey\r\net al. 2025), 6585 (PI: D. Coulter), 6642 (PI: J. Muzerolle\r\nPage), and FRESCO IFU (Matthee et al. 2024; Torralba\r\net al. 2025b).\r\nSoftware used in developing this work includes:\r\nmatplotlib (Hunter 2007), jupyter (Kluyver et al.\r\n2016), IPython (P´erez & Granger 2007), numpy\r\n(Oliphant 2015), scipy (Virtanen et al. 2020), TOPCAT\r\n(Taylor 2005), Astropy (Astropy Collaboration et al.\r\n2013), msaexp (Brammer 2023).","department":[{"_id":"JoMa"}],"project":[{"grant_number":"101076224","_id":"bd9b2118-d553-11ed-ba76-db24564edfea","name":"Young galaxies as tracers and agents of cosmic reionization"}],"author":[{"first_name":"Wendy Q.","full_name":"Sun, Wendy Q.","last_name":"Sun"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee","full_name":"Matthee, Jorryt J"},{"first_name":"Anna","full_name":"De Graaff, Anna","last_name":"De Graaff"},{"last_name":"Chisholm","full_name":"Chisholm, John","first_name":"John"},{"first_name":"Jenny E.","last_name":"Greene","full_name":"Greene, Jenny E."},{"first_name":"Pascal A.","full_name":"Oesch, Pascal A.","last_name":"Oesch"},{"orcid":"0000-0001-5586-6950","id":"018f0249-0e87-11f0-b167-cbce08fbd541","first_name":"Alberto","last_name":"Torralba Torregrosa","full_name":"Torralba Torregrosa, Alberto"},{"first_name":"Raphael E.","last_name":"Hviding","full_name":"Hviding, Raphael E."},{"first_name":"Gabriel","last_name":"Brammer","full_name":"Brammer, Gabriel"},{"first_name":"Robert A.","full_name":"Simcoe, Robert A.","last_name":"Simcoe"},{"first_name":"Sownak","last_name":"Bose","full_name":"Bose, Sownak"},{"first_name":"Rychard","full_name":"Bouwens, Rychard","last_name":"Bouwens"},{"last_name":"Dayal","full_name":"Dayal, Pratika","first_name":"Pratika"},{"last_name":"Eilers","full_name":"Eilers, Anna Christina","first_name":"Anna Christina"},{"full_name":"Fei, Qinyue","last_name":"Fei","first_name":"Qinyue"},{"last_name":"Furtak","full_name":"Furtak, Lukas J.","first_name":"Lukas J."},{"first_name":"Rashmi","last_name":"Gottumukkala","full_name":"Gottumukkala, Rashmi"},{"last_name":"Goulding","full_name":"Goulding, Andy","first_name":"Andy"},{"full_name":"Heintz, Kasper E.","last_name":"Heintz","first_name":"Kasper E."},{"first_name":"Michaela","last_name":"Hirschmann","full_name":"Hirschmann, Michaela"},{"first_name":"Vasily","last_name":"Kokorev","full_name":"Kokorev, Vasily"},{"last_name":"Leja","full_name":"Leja, Joel","first_name":"Joel"},{"full_name":"Liu, Zhaoran","last_name":"Liu","first_name":"Zhaoran"},{"first_name":"Priyamvada","last_name":"Natarajan","full_name":"Natarajan, Priyamvada"},{"full_name":"Santarelli, Andrew D.","last_name":"Santarelli","first_name":"Andrew D."},{"full_name":"Setton, David J.","last_name":"Setton","first_name":"David J."},{"first_name":"Aaron","full_name":"Smith, Aaron","last_name":"Smith"},{"last_name":"Tacchella","full_name":"Tacchella, Sandro","first_name":"Sandro"},{"full_name":"Volonteri, Marta","last_name":"Volonteri","first_name":"Marta"},{"full_name":"Walter, Fabian","last_name":"Walter","first_name":"Fabian"},{"first_name":"Andrea","full_name":"Weibel, Andrea","last_name":"Weibel"},{"last_name":"Williams","full_name":"Williams, Christina C.","first_name":"Christina C."}],"OA_type":"diamond","external_id":{"arxiv":["2601.20929"]},"scopus_import":"1"},{"article_number":"1793713","external_id":{"pmid":["42088272"]},"OA_type":"gold","author":[{"last_name":"Tocino-Márquez","full_name":"Tocino-Márquez, Inmaculada","first_name":"Inmaculada"},{"last_name":"Zehl","full_name":"Zehl, Martin","first_name":"Martin","id":"8e016d5b-5d77-11f0-86d2-96cdb3922a55","orcid":"0000-0001-9685-0373"},{"full_name":"Batajic, Jovana","last_name":"Batajic","first_name":"Jovana"},{"last_name":"Séneca","full_name":"Séneca, Joana","first_name":"Joana"},{"first_name":"Petra","full_name":"Pjevac, Petra","last_name":"Pjevac"},{"first_name":"José","full_name":"Murillo-Alba, José","last_name":"Murillo-Alba"},{"last_name":"Martín","full_name":"Martín, Jesús","first_name":"Jesús"},{"last_name":"Sekurova","full_name":"Sekurova, Olga N.","first_name":"Olga N."},{"first_name":"Sergey B.","last_name":"Zotchev","full_name":"Zotchev, Sergey B."}],"acknowledgement":"The computational results of this work have been achieved using the Life Science Compute Cluster (LiSC) of the University of Vienna. We additionally thank Julia Ramesmayer for assistance during DNA extraction and sample preparation for long-read sequencing. Support from the Mass Spectrometry Centre of the Faculty of Chemistry, University of Vienna, is thankfully acknowledged.\r\nThe author(s) declared that financial support was received for this work and/or its publication. This work was supported by the University of Vienna via the Research Platform Secondary Metabolomes of Bacterial Communities (MetaBac). Open access funding provided by University of Vienna. ","department":[{"_id":"MassSpec"}],"type":"journal_article","article_processing_charge":"Yes","oa":1,"citation":{"ama":"Tocino-Márquez I, Zehl M, Batajic J, et al. Unveiling the genomes and secondary metabolomes of Streptomyces spp. from freshwater sediments. <i>Frontiers in Microbiology</i>. 2026;17. doi:<a href=\"https://doi.org/10.3389/fmicb.2026.1793713\">10.3389/fmicb.2026.1793713</a>","short":"I. Tocino-Márquez, M. Zehl, J. Batajic, J. Séneca, P. Pjevac, J. Murillo-Alba, J. Martín, O.N. Sekurova, S.B. Zotchev, Frontiers in Microbiology 17 (2026).","chicago":"Tocino-Márquez, Inmaculada, Martin Zehl, Jovana Batajic, Joana Séneca, Petra Pjevac, José Murillo-Alba, Jesús Martín, Olga N. Sekurova, and Sergey B. Zotchev. “Unveiling the Genomes and Secondary Metabolomes of Streptomyces Spp. from Freshwater Sediments.” <i>Frontiers in Microbiology</i>. Frontiers Media, 2026. <a href=\"https://doi.org/10.3389/fmicb.2026.1793713\">https://doi.org/10.3389/fmicb.2026.1793713</a>.","mla":"Tocino-Márquez, Inmaculada, et al. “Unveiling the Genomes and Secondary Metabolomes of Streptomyces Spp. from Freshwater Sediments.” <i>Frontiers in Microbiology</i>, vol. 17, 1793713, Frontiers Media, 2026, doi:<a href=\"https://doi.org/10.3389/fmicb.2026.1793713\">10.3389/fmicb.2026.1793713</a>.","ista":"Tocino-Márquez I, Zehl M, Batajic J, Séneca J, Pjevac P, Murillo-Alba J, Martín J, Sekurova ON, Zotchev SB. 2026. Unveiling the genomes and secondary metabolomes of Streptomyces spp. from freshwater sediments. Frontiers in Microbiology. 17, 1793713.","apa":"Tocino-Márquez, I., Zehl, M., Batajic, J., Séneca, J., Pjevac, P., Murillo-Alba, J., … Zotchev, S. B. (2026). Unveiling the genomes and secondary metabolomes of Streptomyces spp. from freshwater sediments. <i>Frontiers in Microbiology</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fmicb.2026.1793713\">https://doi.org/10.3389/fmicb.2026.1793713</a>","ieee":"I. Tocino-Márquez <i>et al.</i>, “Unveiling the genomes and secondary metabolomes of Streptomyces spp. from freshwater sediments,” <i>Frontiers in Microbiology</i>, vol. 17. Frontiers Media, 2026."},"day":"20","OA_place":"publisher","file_date_updated":"2026-06-10T07:46:30Z","intvolume":"        17","publisher":"Frontiers Media","article_type":"original","date_created":"2026-06-08T08:34:10Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1664-302X"]},"pmid":1,"oa_version":"Published Version","DOAJ_listed":"1","doi":"10.3389/fmicb.2026.1793713","file":[{"checksum":"31fb6b98c8a6d4007cb21808c6d2d9e3","success":1,"file_name":"2026_FrontiersMicrobiology_TocinoMarquez.pdf","date_updated":"2026-06-10T07:46:30Z","creator":"dernst","file_id":"21989","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":3582644,"date_created":"2026-06-10T07:46:30Z"}],"abstract":[{"text":"Several Streptomyces strains were isolated from freshwater sediments collected in the Laxenburg ponds (Lower Austria). Genome sequencing and bioinformatics analyses revealed biosynthetic gene clusters (BGCs) that may specify production of chemically diverse secondary metabolites. Various culture conditions were employed to induce metabolite production, and subsequent LC-MS analyses facilitated the identification of the produced compounds and their correlation with the corresponding BGCs. These analyses of sediment-derived Streptomyces spp. highlight their extensive biosynthetic potential, revealing a diverse range of bioactive secondary metabolites, including siderophores, antibiotics, and other compounds with potential therapeutic applications. Genomes of two Streptomyces isolates, one of them representing a potentially new species, harbored several uncharacterized BGCs that may specify biosynthesis of novel secondary metabolites. Although targeted overexpression of pathway-specific regulators from these BGCs did not yield additional metabolites, whereas knockout experiments led to metabolic changes, presumably reflecting regulatory or compensatory interactions between multiple biosynthetic pathways. Continued exploration of these strains and their BGCs may lead to the discovery of new bioactive molecules with pharmaceutical and biotechnological applications.","lang":"eng"}],"publication":"Frontiers in Microbiology","publication_status":"published","title":"Unveiling the genomes and secondary metabolomes of Streptomyces spp. from freshwater sediments","volume":17,"PlanS_conform":"1","status":"public","month":"04","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","ddc":["572"],"year":"2026","date_updated":"2026-06-10T07:49:04Z","language":[{"iso":"eng"}],"quality_controlled":"1","_id":"21953","date_published":"2026-04-20T00:00:00Z"},{"publisher":"Springer Nature","article_type":"original","date_created":"2026-06-08T08:34:43Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","publication_identifier":{"issn":["0924-9907"],"eissn":["1573-7683"]},"doi":"10.1007/s10851-026-01300-1","abstract":[{"lang":"eng","text":"We investigate a framework for train-free MRI segmentation based on Topological Data Analysis. The pipeline proceeds in three steps, first identifying the whole object to segment via automatic thresholding, then detecting a distinctive subset whose topology is known in advance, and finally deducing the various components of the segmentation. A key ingredient is the extraction of approximate representative cycles from persistence diagrams, which provides an interpretable link between persistent features and anatomical components. To clarify the method’s scope, we make the underlying topological and intensity assumptions explicit, quantify when they hold on real data, and analyze typical failure modes. We evaluate the approach on glioblastoma and on fetal cortical plate segmentation, with comparisons to unsupervised and deep-learning references. By operating without large annotated datasets, the method is well suited to scarce-data settings and provides an interpretable baseline and practical initialization for expert refinement or learning-based pipelines."}],"file":[{"relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_size":6070434,"date_created":"2026-06-10T07:58:58Z","checksum":"34080653e0f9c6160856a6bbca9b5248","success":1,"file_name":"2026_JourMathImaging_Francois.pdf","date_updated":"2026-06-10T07:58:58Z","creator":"dernst","file_id":"21990"}],"publication":"Journal of Mathematical Imaging and Vision","publication_status":"published","scopus_import":"1","article_number":"20","external_id":{"arxiv":["2401.01160"]},"OA_type":"hybrid","author":[{"first_name":"Anton","last_name":"François","full_name":"François, Anton"},{"last_name":"Tinarrage","full_name":"Tinarrage, Raphaël","first_name":"Raphaël","id":"40ebcc9d-905f-11ef-bf0a-dc475da8a04e","orcid":"0000-0002-1404-1095"}],"issue":"3","department":[{"_id":"UlWa"}],"acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).","type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"citation":{"chicago":"François, Anton, and Raphaël Tinarrage. “Train-Free Segmentation in MRI with Cubical Persistent Homology.” <i>Journal of Mathematical Imaging and Vision</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s10851-026-01300-1\">https://doi.org/10.1007/s10851-026-01300-1</a>.","short":"A. François, R. Tinarrage, Journal of Mathematical Imaging and Vision 68 (2026).","ama":"François A, Tinarrage R. Train-free segmentation in MRI with cubical persistent homology. <i>Journal of Mathematical Imaging and Vision</i>. 2026;68(3). doi:<a href=\"https://doi.org/10.1007/s10851-026-01300-1\">10.1007/s10851-026-01300-1</a>","ieee":"A. François and R. Tinarrage, “Train-free segmentation in MRI with cubical persistent homology,” <i>Journal of Mathematical Imaging and Vision</i>, vol. 68, no. 3. Springer Nature, 2026.","mla":"François, Anton, and Raphaël Tinarrage. “Train-Free Segmentation in MRI with Cubical Persistent Homology.” <i>Journal of Mathematical Imaging and Vision</i>, vol. 68, no. 3, 20, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s10851-026-01300-1\">10.1007/s10851-026-01300-1</a>.","ista":"François A, Tinarrage R. 2026. Train-free segmentation in MRI with cubical persistent homology. Journal of Mathematical Imaging and Vision. 68(3), 20.","apa":"François, A., &#38; Tinarrage, R. (2026). Train-free segmentation in MRI with cubical persistent homology. <i>Journal of Mathematical Imaging and Vision</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10851-026-01300-1\">https://doi.org/10.1007/s10851-026-01300-1</a>"},"day":"25","OA_place":"publisher","file_date_updated":"2026-06-10T07:58:58Z","intvolume":"        68","month":"05","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["510"],"year":"2026","language":[{"iso":"eng"}],"date_updated":"2026-06-10T08:00:52Z","quality_controlled":"1","_id":"21954","date_published":"2026-05-25T00:00:00Z","title":"Train-free segmentation in MRI with cubical persistent homology","volume":68,"arxiv":1,"corr_author":"1","PlanS_conform":"1","status":"public"},{"external_id":{"pmid":["42235510"]},"scopus_import":"1","author":[{"first_name":"Samuel J.","last_name":"Walker","full_name":"Walker, Samuel J."},{"full_name":"Lowenstein, Elijah D.","last_name":"Lowenstein","first_name":"Elijah D."},{"full_name":"Douglass, Amelia May Barnett","last_name":"Douglass","id":"de5f6fda-80fb-11ef-996f-a8c4ecd8e289","first_name":"Amelia May Barnett","orcid":"0000-0001-5398-6473"},{"last_name":"Thomas","full_name":"Thomas, Callum M.P.","first_name":"Callum M.P."},{"full_name":"Madara, Joseph C.","last_name":"Madara","first_name":"Joseph C."},{"last_name":"Kucukdereli","full_name":"Kucukdereli, Hakan","first_name":"Hakan"},{"first_name":"Eunice A.","last_name":"Barbosa-Meillon","full_name":"Barbosa-Meillon, Eunice A."},{"last_name":"Tao","full_name":"Tao, Jenkang","first_name":"Jenkang"},{"last_name":"Resch","full_name":"Resch, Jon M.","first_name":"Jon M."},{"first_name":"Bradford B.","last_name":"Lowell","full_name":"Lowell, Bradford B."}],"OA_type":"green","department":[{"_id":"AmDo"}],"acknowledgement":"We thank all members of the B.B.L. laboratory for helpful discussions. We\r\nthank the BADERC and BNORC transgenic cores (NIH P30DK057521 and\r\nP30DK046200) for performing embryo injections to generate knockin mouse\r\nlines. We also thank the BIDMC Energy Balance Core (supported by NIH\r\nS10OD028635 and the Boston Area Diabetes Endocrinology Research Centers, P30DK135043), where Marissa Cortopassi performed indirect calorimetry experiments and Alexander Banks assisted with data analysis and interpretation. Confocal imaging was performed at BIDMC’s Confocal Imaging\r\nCore. We thank Chen Wu for assistance in designing knockin mouse lines.\r\nThis work was supported by the NIH (R01DK134427, R01DK096010, and\r\nR01DK075632 to B.B.L.). Authors were supported by an EMBO Long-Term\r\nFellowship (770-2018, S.J.W.), a T32 Postdoctoral Training Fellowship\r\n(5T32DK007516, E.D.L.), the Charles A. King Trust Postdoctoral Research\r\nFellowship program (A.M.D.), and a K99 Career Development Award\r\n(K99HL144923, J.M.R.).","oa":1,"article_processing_charge":"No","type":"journal_article","citation":{"mla":"Walker, Samuel J., et al. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” <i>Neuron</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">10.1016/j.neuron.2026.05.010</a>.","apa":"Walker, S. J., Lowenstein, E. D., Douglass, A. M., Thomas, C. M. P., Madara, J. C., Kucukdereli, H., … Lowell, B. B. (n.d.). A hypothalamic circuit for anticipating future changes in energy balance. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">https://doi.org/10.1016/j.neuron.2026.05.010</a>","ista":"Walker SJ, Lowenstein ED, Douglass AM, Thomas CMP, Madara JC, Kucukdereli H, Barbosa-Meillon EA, Tao J, Resch JM, Lowell BB. A hypothalamic circuit for anticipating future changes in energy balance. Neuron.","ieee":"S. J. Walker <i>et al.</i>, “A hypothalamic circuit for anticipating future changes in energy balance,” <i>Neuron</i>. Elsevier.","ama":"Walker SJ, Lowenstein ED, Douglass AM, et al. A hypothalamic circuit for anticipating future changes in energy balance. <i>Neuron</i>. doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">10.1016/j.neuron.2026.05.010</a>","short":"S.J. Walker, E.D. Lowenstein, A.M. Douglass, C.M.P. Thomas, J.C. Madara, H. Kucukdereli, E.A. Barbosa-Meillon, J. Tao, J.M. Resch, B.B. Lowell, Neuron (n.d.).","chicago":"Walker, Samuel J., Elijah D. Lowenstein, Amelia M. Douglass, Callum M.P. Thomas, Joseph C. Madara, Hakan Kucukdereli, Eunice A. Barbosa-Meillon, Jenkang Tao, Jon M. Resch, and Bradford B. Lowell. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” <i>Neuron</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">https://doi.org/10.1016/j.neuron.2026.05.010</a>."},"OA_place":"repository","keyword":["hunger","hypothalamus","AGRP neurons","neuroscience","metabolism","homeostasis","feeding","food intake","energy balance","appetite"],"day":"03","publisher":"Elsevier","article_type":"original","date_created":"2026-06-08T09:24:25Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"publication_identifier":{"issn":["0896-6273"],"eissn":[" 1097-4199"]},"oa_version":"Preprint","doi":"10.1016/j.neuron.2026.05.010","publication_status":"inpress","publication":"Neuron","abstract":[{"text":"AgRP neurons cause hunger, the drive to seek and consume food. Their activation by fasting is key for survival and is thought to be triggered by feedback when energy stores are low. However, we know that environmental cues can also regulate AgRP neurons since cues that predict future food intake rapidly inhibit AgRP neurons, but is the converse true: can the prediction of future fasting rapidly activate AgRP neurons? Here, we show in mice that such rapid fasting activation of AgRP neurons does occur. This rapid activation is driven by excitatory input from paraventricular hypothalamic (PVH) neurons expressing Sim2, which are bidirectionally sensitive to predictions of future energy state. Thus, cognitively processed contextual information conveyed by PVHSim2 neurons strongly activates AgRP neurons. Lastly, chronic silencing of PVHSim2 neurons causes persistent hypophagia. This PVHSim2-to-AgRP-neuron circuit, by anticipating and preventing negative energy balance, provides an important new dimension of hunger regulation.","lang":"eng"}],"title":"A hypothalamic circuit for anticipating future changes in energy balance","status":"public","month":"06","year":"2026","language":[{"iso":"eng"}],"date_updated":"2026-06-16T08:35:11Z","quality_controlled":"1","date_published":"2026-06-03T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1101/2025.09.27.678865","open_access":"1"}],"_id":"21955"},{"title":"Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames","status":"public","page":"89","corr_author":"1","supervisor":[{"last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"}],"year":"2026","ddc":["500"],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","month":"06","related_material":{"record":[{"id":"21144","relation":"part_of_dissertation","status":"public"}]},"date_published":"2026-06-09T00:00:00Z","_id":"21957","alternative_title":["ISTA Thesis"],"date_updated":"2026-06-12T10:37:00Z","language":[{"iso":"eng"}],"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"acknowledgement":"Funding: Vienna Graduate School on Computational Optimization (FWF), grant DOI: 10.55776/W1260.","project":[{"grant_number":"W1260-N35","name":"Vienna Graduate School on Computational Optimization","_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A"}],"author":[{"last_name":"Zapata","full_name":"Zapata, Jeferson","id":"00223538-AF8F-11E9-A4C7-F729E6697425","first_name":"Jeferson"}],"OA_place":"publisher","file_date_updated":"2026-06-10T13:33:25Z","day":"09","citation":{"ieee":"J. Zapata, “Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames,” Institute of Science and Technology Austria, 2026.","mla":"Zapata, Jeferson. <i>Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>.","ista":"Zapata J. 2026. Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames. Institute of Science and Technology Austria.","apa":"Zapata, J. (2026). <i>Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>","chicago":"Zapata, Jeferson. “Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>.","ama":"Zapata J. Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>","short":"J. Zapata, Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames, Institute of Science and Technology Austria, 2026."},"oa":1,"article_processing_charge":"No","type":"dissertation","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_created":"2026-06-08T13:29:52Z","publisher":"Institute of Science and Technology Austria","publication_status":"published","file":[{"relation":"source_file","content_type":"application/zip","access_level":"closed","file_size":40811933,"date_created":"2026-06-08T13:20:02Z","checksum":"b11a959e99d3dcf61040282b5c837141","file_name":"istaustriathesis_JZapata.zip","date_updated":"2026-06-08T13:20:02Z","creator":"jzapata","file_id":"21958"},{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":2207892,"date_created":"2026-06-10T13:33:25Z","checksum":"edf1e5899b2e31505cd1aa3fe8bd4b7f","file_name":"4_Final_Thesis_JZapata_REX.pdf","success":1,"date_updated":"2026-06-10T13:33:25Z","creator":"jzapata","file_id":"21992"}],"abstract":[{"text":"This thesis investigates algorithmic certification and approximation methods for degenerate semidefinite programs (SDPs) and the singular roots of polynomial systems. In the first part, we present a hybrid symbolic-numeric algorithm for certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating linear matrix inequalities (LMIs) into a structured polynomial system via facial reduction and incidence varieties, we guarantee the existence of an isolated exact solution. This algebraic reduction enables the certification of maximum-rank numerical approximations using methods from algebraic geometry.\r\n\r\nIn the second part, we address the severe ill-conditioning and loss of quadratic convergence that plague standard path-tracking methods near isolated singular roots. To overcome this, we propose tracking algorithms that achieve superlinear convergence without the computational bloat characteristic of classical deflation techniques. By modeling the solution path as a generalized fractional Puiseux series, our approach combines an explicitly derived algebraic predictor with a localized hyperplane desingularization phase during the corrector step. Furthermore, we introduce a continuous path-limit method and an extension of the geometric sequence rule to directly extract exact fractional exponents. This bypasses traditional heuristic trial-and-error methods and explicitly accommodates sparse series expansions. Numerical experiments confirm that our method significantly reduces the cumulative number of matrix inversions while achieving high-accuracy root approximations, even for heavily degenerate systems exhibiting higher coranks.","lang":"eng"}],"doi":"10.15479/AT-ISTA-21957","degree_awarded":"PhD","oa_version":"Published Version","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-079-4"]}},{"department":[{"_id":"GradSch"},{"_id":"MaSe"}],"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"ec_funded":1,"title":"Research Data: \"Quasi-solitons in Rydberg atom chains\"","author":[{"last_name":"Kerschbaumer","full_name":"Kerschbaumer, Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410","orcid":"0009-0002-2370-8661","first_name":"Aron"}],"OA_place":"repository","file_date_updated":"2026-06-15T22:02:07Z","day":"16","status":"public","oa":1,"article_processing_charge":"No","type":"research_data","citation":{"ieee":"A. Kerschbaumer, “Research Data: ‘Quasi-solitons in Rydberg atom chains.’” Institute of Science and Technology Austria, 2026.","mla":"Kerschbaumer, Aron. <i>Research Data: “Quasi-Solitons in Rydberg Atom Chains.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>.","apa":"Kerschbaumer, A. (2026). Research Data: “Quasi-solitons in Rydberg atom chains.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">https://doi.org/10.15479/AT-ISTA-21960</a>","ista":"Kerschbaumer A. 2026. Research Data: ‘Quasi-solitons in Rydberg atom chains’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>.","chicago":"Kerschbaumer, Aron. “Research Data: ‘Quasi-Solitons in Rydberg Atom Chains.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">https://doi.org/10.15479/AT-ISTA-21960</a>.","short":"A. Kerschbaumer, (2026).","ama":"Kerschbaumer A. Research Data: “Quasi-solitons in Rydberg atom chains.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>"},"corr_author":"1","year":"2026","contributor":[{"last_name":"Kerschbaumer","contributor_type":"contact_person","first_name":"Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410","orcid":"0009-0002-2370-8661"},{"orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym","contributor_type":"supervisor","last_name":"Serbyn"},{"orcid":"0000-0002-3749-6375","first_name":"Jean-Yves Marc","id":"6c292945-a610-11ed-9eec-c3be1ad62a80","contributor_type":"researcher","last_name":"Desaules"},{"first_name":"Marko","contributor_type":"researcher","last_name":"Ljubotina"}],"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"date_created":"2026-06-09T07:17:50Z","month":"06","doi":"10.15479/AT-ISTA-21960","date_published":"2026-06-16T00:00:00Z","_id":"21960","file":[{"file_size":1940,"date_created":"2026-06-15T22:01:57Z","relation":"main_file","content_type":"text/plain","access_level":"open_access","creator":"akerschb","file_id":"22010","date_updated":"2026-06-15T22:01:57Z","checksum":"133269a105e996c6c44fdd56128259c7","file_name":"README.txt","success":1},{"file_size":13259747,"date_created":"2026-06-15T22:02:07Z","relation":"main_file","content_type":"application/zip","access_level":"open_access","checksum":"759f9649c3919f4c4ad37a1d104ea32a","file_name":"Soliton_Data.zip","success":1,"creator":"akerschb","file_id":"22011","date_updated":"2026-06-15T22:02:07Z"}],"abstract":[{"lang":"eng","text":"Solitons - localized wave packets that travel without spreading - play a central role in understanding transport and properties of nonlinear systems. In quantum many-body systems, however, such robust excitations are typically destroyed by thermalization. Here, we theoretically demonstrate the existence of solitonic excitations in high-energy states of Rydberg atom chains in the regime of strong nearest-neighbor Rydberg blockade. \r\nThese localized wave packets propagate directionally atop a special class of reviving initial states related to quantum many-body scars and are capable of carrying energy. Exhibiting long coherence times, these states constitute a form of non-ergodic quantum dynamics and can be efficiently implemented on Rydberg atom simulators. In this work, in addition to a phenomenological description of solitons, we identify their counterpart in a classical nonlinear dynamical system, demonstrate their potential use in quantum information transfer, and conjecture their relevance for anomalous energy transport reported in numerical studies of Rydberg atom arrays."}],"date_updated":"2026-06-16T08:00:38Z","oa_version":"Published Version"},{"date_published":"2026-05-05T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.64898/2026.05.01.722172","open_access":"1"}],"_id":"21962","language":[{"iso":"eng"}],"date_updated":"2026-06-16T08:45:25Z","year":"2026","ddc":["570"],"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"has_accepted_license":"1","month":"05","status":"public","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"Bio"}],"title":"Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner","publication_status":"submitted","abstract":[{"text":"The generation of faithful cell-type diversity and correct projection neuron numbers is essential for cerebral cortex development. Corticogenesis is however susceptible to genetic interference of critical signaling pathways, including mutations in Mtor/Rptor that lead to microcephaly. How the loss of Rptor/mTORC1 function affects cortical developmental programs, at single cell level, is still unknown. Here, we utilized Mosaic Analysis with Double Markers (MADM) technology to probe Rptor gene function upon sparse single cell- or global tissue-wide ablation. We found that tissue-wide effects drive the etiology of cortical microcephaly upon loss of Rptor, rather than deficits in projection neuron genesis. Conversely, Rptor function is cell-autonomously required for postnatal projection neuron survival in a highly cell-type-specific manner. Collectively, our results suggest that the fine balance of precise cell-type-specific cell-autonomous Rptor/mTORC1 function in concert with non-cell-autonomous tissue-wide effects is essential for the development of a properly-sized cerebral cortex with accurate projection neuron diversity.","lang":"eng"}],"publication":"bioRxiv","doi":"10.64898/2026.05.01.722172","oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-06-09T08:08:18Z","OA_place":"repository","day":"05","citation":{"chicago":"Villalba Requena, Ana, Robert J Beattie, Florian Pauler, Carmen Streicher, Osvaldo Miranda, Thomas Krausgruber, Martin Senekowitsch, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>.","ama":"Villalba Requena A, Beattie RJ, Pauler F, et al. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>","short":"A. Villalba Requena, R.J. Beattie, F. Pauler, C. Streicher, O. Miranda, T. Krausgruber, M. Senekowitsch, M. Farlik, C. Bock, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","ieee":"A. Villalba Requena <i>et al.</i>, “Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner,” <i>bioRxiv</i>. .","mla":"Villalba Requena, Ana, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","ista":"Villalba Requena A, Beattie RJ, Pauler F, Streicher C, Miranda O, Krausgruber T, Senekowitsch M, Farlik M, Bock C, Rülicke T, Hippenmeyer S. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","apa":"Villalba Requena, A., Beattie, R. J., Pauler, F., Streicher, C., Miranda, O., Krausgruber, T., … Hippenmeyer, S. (n.d.). Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>"},"oa":1,"article_processing_charge":"No","type":"preprint","ec_funded":1,"department":[{"_id":"SiHi"}],"acknowledgement":"We thank A. Heger (IST Austria Preclinical Facility), A. Sommer (VBCF GmbH, NGS Unit), and A.\r\nNicolas (IST Austria Lab Support Facility / Mass Spectrometry Facility) for technical support; K. Ferencak,\r\nI. Aykara, P. Hirschfeld, E. Fisher, S. Laukoter, L. Andersen for initial experiments and/or assistance; and\r\nall members of the Hippenmeyer lab for discussion. This research was supported by the Scientific Service\r\nUnits (SSU) of IST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). R.B. received support from FWF Meitner-Programm (M 2416). This\r\nwork was also supported by IST Austria institutional funds; the People Programme (Marie Curie Actions)\r\nof the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement\r\nNo 618444 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation programme (grant agreement No 725780 LinPro) to S.H.","project":[{"call_identifier":"FWF","grant_number":"M02416","_id":"264E56E2-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex"},{"_id":"25D61E48-B435-11E9-9278-68D0E5697425","grant_number":"618444","name":"Molecular Mechanisms of Cerebral Cortex Development","call_identifier":"FP7"},{"grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","_id":"260018B0-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"author":[{"last_name":"Villalba Requena","full_name":"Villalba Requena, Ana","first_name":"Ana","orcid":"0000-0002-5615-5277","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247"},{"last_name":"Beattie","full_name":"Beattie, Robert J","first_name":"Robert J","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8483-8753"},{"full_name":"Pauler, Florian","last_name":"Pauler","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","first_name":"Florian","orcid":"0000-0002-7462-0048"},{"last_name":"Streicher","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","first_name":"Carmen"},{"last_name":"Miranda","full_name":"Miranda, Osvaldo","orcid":"0000-0001-6618-6889","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","first_name":"Osvaldo"},{"first_name":"Thomas","last_name":"Krausgruber","full_name":"Krausgruber, Thomas"},{"first_name":"Martin","last_name":"Senekowitsch","full_name":"Senekowitsch, Martin"},{"first_name":"Matthias","last_name":"Farlik","full_name":"Farlik, Matthias"},{"full_name":"Bock, Christoph","last_name":"Bock","first_name":"Christoph"},{"first_name":"Thomas","last_name":"Rülicke","full_name":"Rülicke, Thomas"},{"first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon"}],"OA_type":"green"},{"_id":"21963","main_file_link":[{"url":"https://doi.org/10.64898/2026.05.01.722191","open_access":"1"}],"date_published":"2026-05-05T00:00:00Z","language":[{"iso":"eng"}],"date_updated":"2026-06-16T08:57:20Z","ddc":["570"],"year":"2026","month":"05","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"has_accepted_license":"1","status":"public","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","title":"Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production","abstract":[{"lang":"eng","text":"The cerebral cortex consists of immense numbers of neuronal and glial cell-types derived from radial glial progenitor (RGP) cells. How RGPs generate appropriate quantities of distinct cortical cell-types to safeguard a brain of correct size, is not well understood. However, genetic aberration in human, including mutations in PTEN, lead to cortical malformation such as macrocephaly, albeit with unknown etiology. Here we utilized Mosaic Analysis with Double Markers (MADM)-based clonal analysis and single cell phenotyping to decipher the role of Pten in neurogenic and gliogenic RGP lineage progression during cortical ontogeny. While neurogenic RGP lineage progression and projection neuron production was moderately altered in the absence of Pten, cortical astrocyte production was drastically increased. Through genetic epistasis experiments we show that the loss of Pten uncouples astrocyte generation from essential growth factor signaling hubs, funneling into MAPK. Collectively, our results suggest that Pten regulates RGP lineage progression with distinct sequential functions in cortical projection neurogenesis and astrocyte production to ensure the emergence of a correctly-sized cerebral cortex."}],"publication":"bioRxiv","publication_status":"submitted","doi":"10.64898/2026.05.01.722191","oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-06-09T08:08:53Z","day":"05","OA_place":"repository","citation":{"mla":"Miranda, Osvaldo, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","ista":"Miranda O, Contreras X, Pauler F, Davaatseren A, Amberg N, Streicher C, Villalba Requena A, Heger A-M, Marie C, Hassan BA, Rülicke T, Hippenmeyer S. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","apa":"Miranda, O., Contreras, X., Pauler, F., Davaatseren, A., Amberg, N., Streicher, C., … Hippenmeyer, S. (n.d.). Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>","ieee":"O. Miranda <i>et al.</i>, “Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production,” <i>bioRxiv</i>. .","ama":"Miranda O, Contreras X, Pauler F, et al. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>","short":"O. Miranda, X. Contreras, F. Pauler, A. Davaatseren, N. Amberg, C. Streicher, A. Villalba Requena, A.-M. Heger, C. Marie, B.A. Hassan, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","chicago":"Miranda, Osvaldo, Ximena Contreras, Florian Pauler, Amarbayasgalan Davaatseren, Nicole Amberg, Carmen Streicher, Ana Villalba Requena, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>."},"article_processing_charge":"No","type":"preprint","oa":1,"ec_funded":1,"project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression"},{"call_identifier":"H2020","grant_number":"725780","_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}],"acknowledgement":"We thank Kay-Uwe Wagner (Wayne State University) for generously sharing Jak1/2–flox mouse lines; A.\r\nSommer (VBCF GmbH, NGS Unit) for technical support; N. Kim, V. Mick, S. Schnabl, S. Gobeil, and L.\r\nAndersen for technical assistance; all members of the Hippenmeyer lab for discussion and B. Novitch for\r\ncomments on earlier versions of the manuscript. This research was supported by the Scientific Service Units\r\n(SSU) of IST Austria through resources provided by the Imaging and Optics Facility (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). O.A.M received support from the Austrian Academy of Sciences\r\nÖAW (DOC 186584), and N.A. from FWF Elise Richter Program (Grant V1041T). This work was also\r\nsupported by IST Austria institutional funds; FWF SFB F78 (Neuro Stem Modulation) to S.H., and the\r\nEuropean Research Council (ERC) under the European Union’s Horizon 2020 research and innovation\r\nprogramme (grant agreement No 725780 LinPro) to S.H.","department":[{"_id":"SiHi"},{"_id":"PreCl"},{"_id":"GradSch"}],"OA_type":"green","author":[{"full_name":"Miranda, Osvaldo","last_name":"Miranda","first_name":"Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","orcid":"0000-0001-6618-6889"},{"id":"475990FE-F248-11E8-B48F-1D18A9856A87","first_name":"Ximena","full_name":"Contreras, Ximena","last_name":"Contreras"},{"full_name":"Pauler, Florian","last_name":"Pauler","first_name":"Florian","orcid":"0000-0002-7462-0048","id":"48EA0138-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Amarbayasgalan","id":"70ADC922-B424-11E9-99E3-BA18E6697425","full_name":"Davaatseren, Amarbayasgalan","last_name":"Davaatseren"},{"id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","first_name":"Nicole","orcid":"0000-0002-3183-8207","full_name":"Amberg, Nicole","last_name":"Amberg"},{"full_name":"Streicher, Carmen","last_name":"Streicher","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","first_name":"Carmen"},{"last_name":"Villalba Requena","full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana","orcid":"0000-0002-5615-5277"},{"id":"4B76FFD2-F248-11E8-B48F-1D18A9856A87","first_name":"Anna-Magdalena","last_name":"Heger","full_name":"Heger, Anna-Magdalena"},{"full_name":"Marie, Corentine","last_name":"Marie","first_name":"Corentine"},{"first_name":"Bassem A.","last_name":"Hassan","full_name":"Hassan, Bassem A."},{"first_name":"Thomas","full_name":"Rülicke, Thomas","last_name":"Rülicke"},{"first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon"}]},{"language":[{"iso":"eng"}],"date_updated":"2026-06-12T12:43:34Z","oa_version":"Preprint","doi":"10.1101/2025.04.09.647826","date_published":"2026-04-23T00:00:00Z","publication_status":"draft","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.04.09.647826"}],"_id":"21968","publication":"bioRxiv","abstract":[{"lang":"eng","text":"Balancing selection, a form of selection that maintains genetic diversity, is difficult to detect, and the importance of balancing selection for the maintenance of genetic variation may be larger than often assumed. We model the possibility that the diversity-promoting effects of balancing selection extend to other loci that show sign epistasis with a locus under balancing selection. Rather than focusing on overdominance, as was done in previous efforts, we explore the effects of negative frequency dependence and show that this has important effects on the conditions under which the diversity-promoting effect of epistasis can occur in diploids. Our results show that not only recombination rate but also the dominance of sign epistasis are key parameters that determine the maintenance of polymorphism beyond the locus under direct balancing selection. We suggest that the effect we explore may play a significant role, especially when balancing selection acts on major effect loci."}],"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"21918"}]},"date_created":"2026-06-09T12:26:11Z","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"month":"04","year":"2026","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"type":"preprint","article_processing_charge":"No","citation":{"short":"K. Khudiakova, N.H. Barton, G. Arnqvist, BioRxiv (n.d.).","ama":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>","chicago":"Khudiakova, Kseniia, Nicholas H Barton, and Goran Arnqvist. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>.","mla":"Khudiakova, Kseniia, et al. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>.","apa":"Khudiakova, K., Barton, N. H., &#38; Arnqvist, G. (n.d.). Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>","ista":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv, <a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>.","ieee":"K. Khudiakova, N. H. Barton, and G. Arnqvist, “Sign epistasis extends the effects of balancing selection on genetic diversity,” <i>bioRxiv</i>. ."},"corr_author":"1","OA_place":"repository","day":"23","status":"public","title":"Sign epistasis extends the effects of balancing selection on genetic diversity","author":[{"orcid":"0000-0002-6246-1465","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","first_name":"Kseniia","last_name":"Khudiakova","full_name":"Khudiakova, Kseniia"},{"orcid":"0000-0002-8548-5240","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","last_name":"Barton"},{"full_name":"Arnqvist, Goran","last_name":"Arnqvist","first_name":"Goran"}],"OA_type":"green","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"acknowledgement":"This work was funded by grants from the Swedish Research Council (2023-03730 to G.A.) and the DOC fellowship from the Austrian Academy of Science (26293 to K.K.).","project":[{"_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8","grant_number":"26293","name":"The impact of deleterious mutations on small populations"}]},{"author":[{"full_name":"Bleile, Yossi","last_name":"Bleile","orcid":"0000-0002-4861-9174","id":"920a7385-7995-11ef-9bfd-8c434cd8f3c2","first_name":"Yossi"},{"first_name":"Emanuele","full_name":"Cortinovis, Emanuele","last_name":"Cortinovis"}],"license":"https://opensource.org/licenses/MIT","title":"Quadrix","project":[{"name":"Quantitative Unbiased Shape Analysis with Geometry & Topology","grant_number":"ESP 9584724","_id":"9106a876-16d5-11f0-9cad-bbf11c9952f9"}],"department":[{"_id":"HeEd"}],"corr_author":"1","citation":{"ama":"Bokor Bleile Y, Cortinovis E. Quadrix. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>","short":"Y. Bokor Bleile, E. Cortinovis, (2026).","chicago":"Bokor Bleile, Yossi, and Emanuele Cortinovis. “Quadrix.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">https://doi.org/10.15479/AT-ISTA-21971</a>.","ista":"Bokor Bleile Y, Cortinovis E. 2026. Quadrix, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>.","apa":"Bokor Bleile, Y., &#38; Cortinovis, E. (2026). Quadrix. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">https://doi.org/10.15479/AT-ISTA-21971</a>","mla":"Bokor Bleile, Yossi, and Emanuele Cortinovis. <i>Quadrix</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>.","ieee":"Y. Bokor Bleile and E. Cortinovis, “Quadrix.” Institute of Science and Technology Austria, 2026."},"type":"software","oa":1,"status":"public","day":"15","keyword":["quadratics","mathematics","dendrites","geometry","topology"],"file_date_updated":"2026-06-15T08:14:24Z","month":"06","date_created":"2026-06-09T19:19:13Z","tmp":{"name":"The MIT License","short":"MIT","legal_code_url":"https://opensource.org/licenses/MIT"},"has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","year":"2026","date_updated":"2026-06-15T23:00:03Z","_id":"21971","abstract":[{"lang":"eng","text":"A Rust library for analyzing dendritic structures using quadric matrices. This project provides efficient tools for representing dendritic trees, computing quadric error metrics, and visualizing eigenvalue distributions on hexagonal plots.\r\n\r\nThis library implements quadric-based geometric analysis of dendritic structures, commonly found in neuroscience applications. Key features include:\r\n\r\nTree data structures: Hierarchical vertex and edge representations for dendritic trees\r\nQuadric matrices: Computation of quadric error metrics for edges and vertices\r\nVisualisation: Hexagonal plot generation using NormPolar transformations\r\nInteractive tools: Desktop application with plotting capabilities"}],"file":[{"date_updated":"2026-06-09T19:16:02Z","creator":"ybleile","file_id":"21974","checksum":"48f633b6767c4b15dd6220ca2b4dc175","success":1,"file_name":"LICENSE","relation":"main_file","content_type":"application/octet-stream","access_level":"open_access","file_size":1081,"date_created":"2026-06-09T19:16:02Z"},{"creator":"ybleile","file_id":"21975","date_updated":"2026-06-09T19:16:27Z","checksum":"de25d0b224acbde3d38f837fdd8f97d5","file_name":"quadrix-x64.exe","success":1,"file_size":11308032,"date_created":"2026-06-09T19:16:27Z","content_type":"application/octet-stream","relation":"main_file","access_level":"open_access"},{"access_level":"open_access","relation":"main_file","content_type":"application/octet-stream","date_created":"2026-06-09T19:16:28Z","file_size":10655744,"date_updated":"2026-06-09T19:16:28Z","file_id":"21976","creator":"ybleile","file_name":"quadrix-arm64.exe","success":1,"checksum":"a7b94a7380dc178e76ebdba9f1fa45c2"},{"checksum":"2404aa8619a56668bd95032791ee1250","file_name":"Quadrix Desktop.app.zip","success":1,"date_updated":"2026-06-09T19:16:27Z","creator":"ybleile","file_id":"21977","relation":"main_file","content_type":"application/zip","access_level":"open_access","file_size":2032,"date_created":"2026-06-09T19:16:27Z"},{"access_level":"open_access","content_type":"application/octet-stream","relation":"main_file","date_created":"2026-06-09T19:16:40Z","file_size":12187896,"date_updated":"2026-06-09T19:16:40Z","file_id":"21978","creator":"ybleile","file_name":"quadrix-arm64","success":1,"checksum":"106930f81563c5c719a5f4030b5ca5ed"},{"date_updated":"2026-06-09T19:16:52Z","creator":"ybleile","file_id":"21979","checksum":"0e6ba129318446676f220087e7e6ff41","file_name":"quadrix-x64","success":1,"relation":"main_file","content_type":"application/octet-stream","access_level":"open_access","file_size":20587592,"date_created":"2026-06-09T19:16:52Z"},{"file_name":"Quadrix.zip","checksum":"f0b03385d17df049219465ab7403fe09","file_id":"21972","creator":"pub-gitlab-bot","date_updated":"2026-06-09T19:19:12Z","date_created":"2026-06-09T19:19:12Z","file_size":1914198,"access_level":"open_access","relation":"main_file","content_type":"application/gzip"},{"checksum":"ede0bbb24bf41ab4009cf1b6a9009671","file_name":"THIRD_PARTY_LICENSES.zip","creator":"ybleile","file_id":"21993","date_updated":"2026-06-10T19:09:38Z","file_size":37557,"date_created":"2026-06-10T19:09:38Z","content_type":"application/zip","relation":"supplementary_material","access_level":"open_access"},{"file_size":3839,"date_created":"2026-06-15T08:13:32Z","content_type":"text/markdown","relation":"main_file","access_level":"open_access","creator":"ybleile","file_id":"22009","date_updated":"2026-06-15T08:13:32Z","checksum":"f3c5fcc62c88e449ab5c660244df5aef","file_name":"README.md","success":1},{"date_created":"2026-06-15T08:14:24Z","file_size":1912923,"access_level":"open_access","relation":"main_file","content_type":"application/gzip","file_id":"22008","creator":"pub-gitlab-bot","date_updated":"2026-06-15T08:14:24Z","file_name":"Quadrix.zip","checksum":"aa74828c3165aafcdee4ddcc9ecd37ac"}],"date_published":"2026-06-15T00:00:00Z","doi":"10.15479/AT-ISTA-21971"},{"quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-06-16T09:13:30Z","_id":"21980","date_published":"2026-06-01T00:00:00Z","month":"06","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","ddc":["540"],"year":"2026","corr_author":"1","PlanS_conform":"1","page":"7429–7434","status":"public","volume":26,"title":"A computationally efficient and accurate method for predicting conductance of single-molecule junctions","oa_version":"Published Version","pmid":1,"publication_identifier":{"issn":["1530-6984"],"eissn":["1530-6992"]},"file":[{"file_name":"2026_NanoLetters_Gulyaev.pdf","success":1,"checksum":"897551374cac28e0db26dcb0b676b8e7","date_updated":"2026-06-16T09:11:35Z","file_id":"22013","creator":"dernst","access_level":"open_access","relation":"main_file","content_type":"application/pdf","date_created":"2026-06-16T09:11:35Z","file_size":3362800}],"abstract":[{"text":"Despite significant progress in the field of molecular electronics over the last two decades, the quantitative prediction of metal-molecule-metal junction conductance remains a challenge. The standard computational framework combines density functional theory (DFT) with nonequilibrium Green’s functions (NEGF) using low-rung exchange-correlation functionals such as PBE, which overestimate the conductances. More advanced correction methods exist but require complex workflows and high computational cost, limiting their accessibility. Here, we introduce a physically motivated approach that approximates results obtained with high-rung functionals. Our method fits the PBE-calculated transmission to a Breit-Wigner form and subsequently refines the fit parameters using molecular orbital energies and metal densities of states computed for the isolated subsystems with high-rung functionals. This approach is applicable to a broad range of molecular junctions yielding conductance values in quantitative agreement with experiments. Our approach is simple, low-cost, and accurate, making it well-suited for routine and large-scale prediction of single-molecule junction conductance.","lang":"eng"}],"publication":"Nano Letters","publication_status":"published","doi":"10.1021/acs.nanolett.6c01462","date_created":"2026-06-10T07:27:19Z","publisher":"American Chemical Society","article_type":"letter_note","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"A. Gulyaev, J. Hazarika, Z.-F. Liu, and L. Venkataraman, “A computationally efficient and accurate method for predicting conductance of single-molecule junctions,” <i>Nano Letters</i>, vol. 26, no. 22. American Chemical Society, pp. 7429–7434, 2026.","ista":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. 2026. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. Nano Letters. 26(22), 7429–7434.","apa":"Gulyaev, A., Hazarika, J., Liu, Z.-F., &#38; Venkataraman, L. (2026). A computationally efficient and accurate method for predicting conductance of single-molecule junctions. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">https://doi.org/10.1021/acs.nanolett.6c01462</a>","mla":"Gulyaev, Artem, et al. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>, vol. 26, no. 22, American Chemical Society, 2026, pp. 7429–7434, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">10.1021/acs.nanolett.6c01462</a>.","chicago":"Gulyaev, Artem, Jyotisman Hazarika, Zhen-Fei Liu, and Latha Venkataraman. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">https://doi.org/10.1021/acs.nanolett.6c01462</a>.","ama":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. <i>Nano Letters</i>. 2026;26(22):7429–7434. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">10.1021/acs.nanolett.6c01462</a>","short":"A. Gulyaev, J. Hazarika, Z.-F. Liu, L. Venkataraman, Nano Letters 26 (2026) 7429–7434."},"article_processing_charge":"Yes (via OA deal)","type":"journal_article","oa":1,"intvolume":"        26","day":"01","file_date_updated":"2026-06-16T09:11:35Z","OA_place":"publisher","OA_type":"hybrid","author":[{"first_name":"Artem","id":"83ed7901-7380-11f0-bf20-a0788d5e654d","full_name":"Gulyaev, Artem","last_name":"Gulyaev"},{"id":"d87714c4-663d-11f0-bd06-caece19833e5","orcid":"0009-0007-2542-7878","first_name":"Jyotisman","last_name":"Hazarika","full_name":"Hazarika, Jyotisman"},{"full_name":"Liu, Zhen-Fei","last_name":"Liu","first_name":"Zhen-Fei"},{"last_name":"Venkataraman","full_name":"Venkataraman, Latha","first_name":"Latha","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf","orcid":"0000-0002-6957-6089"}],"scopus_import":"1","external_id":{"pmid":["42223342"]},"issue":"22","department":[{"_id":"LaVe"},{"_id":"GradSch"}],"acknowledgement":"This work was supported primarily by the Institute of Science and Technology Austria. L.V. was supported in part by the National Science Foundation (No. NSF-DMR 2241180). Z.-F.L. was supported by an NSF CAREER Award, No. DMR-2044552 and an Alfred P. Sloan Research Fellowship, No. FG-2024-21750."},{"title":"An easier way to compute 2-cocycles coming from a reduction for semidirect products","volume":227,"status":"public","PlanS_conform":"1","corr_author":"1","arxiv":1,"ddc":["000"],"year":"2026","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"05","date_published":"2026-05-21T00:00:00Z","_id":"21981","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.geomphys.2026.105878"}],"date_updated":"2026-06-16T09:23:39Z","language":[{"iso":"eng"}],"quality_controlled":"1","department":[{"_id":"GradSch"}],"external_id":{"arxiv":["2509.16169"]},"article_number":"105878","scopus_import":"1","author":[{"last_name":"Goncharov","full_name":"Goncharov, Viacheslav","first_name":"Viacheslav","id":"8a0e2993-7114-11f0-b60e-f50e633649d8"}],"OA_type":"hybrid","OA_place":"publisher","day":"21","intvolume":"       227","oa":1,"type":"journal_article","article_processing_charge":"Yes (via OA deal)","citation":{"chicago":"Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">https://doi.org/10.1016/j.geomphys.2026.105878</a>.","short":"V. Goncharov, Journal of Geometry and Physics 227 (2026).","ama":"Goncharov V. An easier way to compute 2-cocycles coming from a reduction for semidirect products. <i>Journal of Geometry and Physics</i>. 2026;227. doi:<a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">10.1016/j.geomphys.2026.105878</a>","ieee":"V. Goncharov, “An easier way to compute 2-cocycles coming from a reduction for semidirect products,” <i>Journal of Geometry and Physics</i>, vol. 227. Elsevier, 2026.","mla":"Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>, vol. 227, 105878, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">10.1016/j.geomphys.2026.105878</a>.","apa":"Goncharov, V. (2026). An easier way to compute 2-cocycles coming from a reduction for semidirect products. <i>Journal of Geometry and Physics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">https://doi.org/10.1016/j.geomphys.2026.105878</a>","ista":"Goncharov V. 2026. An easier way to compute 2-cocycles coming from a reduction for semidirect products. Journal of Geometry and Physics. 227, 105878."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Elsevier","article_type":"original","date_created":"2026-06-10T07:29:13Z","doi":"10.1016/j.geomphys.2026.105878","publication_status":"epub_ahead","abstract":[{"lang":"eng","text":"For Hamiltonian actions of semidirect products G = FxH, we study 2-cocycles arising from residual Hamiltonian actions of F on Hamiltonian reductions for H. The motivation comes from the study of Teichmüller spaces for surfaces with boundary, which carry Hamiltonian actions of the Virasoro algebra. In this paper, we give a general setup for the problem, and we suggest an easier way to obtain the Gelfand-Fuchs 2-cocycles for Hamiltonian actions on Teichmüller spaces."}],"publication":"Journal of Geometry and Physics","oa_version":"Published Version","publication_identifier":{"eissn":["1879-1662"],"issn":["0393-0440"]}},{"oa_version":"Published Version","publication_identifier":{"issn":["0022-1236"]},"publication":"Journal of Functional Analysis","file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":2503887,"date_created":"2026-01-05T13:05:47Z","checksum":"ee53d5e695f0df11e017c8c9242a2b04","success":1,"file_name":"2026_JourFuncAnalysis_Cipolloni.pdf","date_updated":"2026-01-05T13:05:47Z","creator":"dernst","file_id":"20947"}],"abstract":[{"text":"We consider the standard overlap (math formular) of any bi-orthogonal family of left and right eigenvectors of a large random matrix X with centred i.i.d. entries and we prove that it decays as an inverse second power of the distance between the corresponding eigenvalues. This extends similar results for the complex Gaussian ensemble from Bourgade and Dubach [15], as well as Benaych-Georges and Zeitouni [13], to any i.i.d. matrix ensemble in both symmetry classes. As a main tool, we prove a two-resolvent local law for the Hermitisation of X uniformly in the spectrum with optimal decay rate and optimal dependence on the density near the spectral edge.","lang":"eng"}],"publication_status":"published","doi":"10.1016/j.jfa.2025.111180","oaworkid":1,"date_created":"2025-09-10T05:46:07Z","publisher":"Elsevier","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ieee":"G. Cipolloni, L. Erdös, and Y. Xu, “Optimal decay of eigenvector overlap for non-Hermitian random matrices,” <i>Journal of Functional Analysis</i>, vol. 290, no. 1. Elsevier, 2026.","ista":"Cipolloni G, Erdös L, Xu Y. 2026. Optimal decay of eigenvector overlap for non-Hermitian random matrices. Journal of Functional Analysis. 290(1), 111180.","apa":"Cipolloni, G., Erdös, L., &#38; Xu, Y. (2026). Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>","mla":"Cipolloni, Giorgio, et al. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>, vol. 290, no. 1, 111180, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>.","chicago":"Cipolloni, Giorgio, László Erdös, and Yuanyuan Xu. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>.","short":"G. Cipolloni, L. Erdös, Y. Xu, Journal of Functional Analysis 290 (2026).","ama":"Cipolloni G, Erdös L, Xu Y. Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. 2026;290(1). doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>"},"type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"intvolume":"       290","day":"01","file_date_updated":"2026-01-05T13:05:47Z","OA_place":"publisher","OA_type":"hybrid","author":[{"full_name":"Cipolloni, Giorgio","last_name":"Cipolloni","first_name":"Giorgio","id":"42198EFA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4901-7992"},{"orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","last_name":"Erdös","full_name":"Erdös, László"},{"orcid":"0000-0003-1559-1205","id":"7902bdb1-a2a4-11eb-a164-c9216f71aea3","first_name":"Yuanyuan","last_name":"Xu","full_name":"Xu, Yuanyuan"}],"scopus_import":"1","article_number":"111180","isi":1,"external_id":{"oaworkid":["w4413883397"],"arxiv":["2411.16572"],"isi":["001583178200001"]},"ec_funded":1,"project":[{"call_identifier":"H2020","_id":"62796744-2b32-11ec-9570-940b20777f1d","name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331"}],"acknowledgement":"Partially supported by ERC Advanced Grant “RMTBeyond” No. 101020331. Partially supported by National Key R&D Program of China No. 2024YFA1013503.","issue":"1","department":[{"_id":"LaEr"}],"quality_controlled":"1","date_updated":"2026-06-03T13:12:14Z","language":[{"iso":"eng"}],"_id":"20328","date_published":"2026-01-01T00:00:00Z","month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["510"],"year":"2026","arxiv":1,"corr_author":"1","PlanS_conform":"1","status":"public","volume":290,"title":"Optimal decay of eigenvector overlap for non-Hermitian random matrices"},{"publication_identifier":{"eissn":["1096-0902"],"issn":["0095-8956"]},"oa_version":"Published Version","doi":"10.1016/j.jctb.2025.09.002","abstract":[{"lang":"eng","text":"We show that if n is odd and p>=Clog n/n, then with high probability Hamilton cycles in G(n,p) span its cycle space. More generally, we show this holds for a class of graphs satisfying certain natural pseudorandom properties. The proof is based on a novel idea of parity-switchers, which can be thought of as analogues of absorbers in the context of cycle spaces. As another application of our method, we show that Hamilton cycles in a near-Dirac graph G, that is, a graph G with odd n vertices and minimum degree n/2+C for sufficiently large constant C, span its cycle space.\r\n"}],"file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":688924,"date_created":"2026-01-05T13:29:34Z","checksum":"60676af4af4b3243ba187e7d65440d99","file_name":"2026_JourCombTheoryB_Christoph.pdf","success":1,"date_updated":"2026-01-05T13:29:34Z","creator":"dernst","file_id":"20953"}],"publication":"Journal of Combinatorial Theory Series B","publication_status":"published","publisher":"Elsevier","article_type":"original","date_created":"2025-10-05T22:01:34Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes (via OA deal)","type":"journal_article","oa":1,"citation":{"chicago":"Christoph, Micha, Rajko Nenadov, and Kalina H Petrova. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>.","short":"M. Christoph, R. Nenadov, K.H. Petrova, Journal of Combinatorial Theory Series B 176 (2026) 254–267.","ama":"Christoph M, Nenadov R, Petrova KH. The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. 2026;176:254-267. doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>","ieee":"M. Christoph, R. Nenadov, and K. H. Petrova, “The Hamilton space of pseudorandom graphs,” <i>Journal of Combinatorial Theory Series B</i>, vol. 176. Elsevier, pp. 254–267, 2026.","mla":"Christoph, Micha, et al. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>, vol. 176, Elsevier, 2026, pp. 254–67, doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>.","ista":"Christoph M, Nenadov R, Petrova KH. 2026. The Hamilton space of pseudorandom graphs. Journal of Combinatorial Theory Series B. 176, 254–267.","apa":"Christoph, M., Nenadov, R., &#38; Petrova, K. H. (2026). The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>"},"day":"01","file_date_updated":"2026-01-05T13:29:34Z","OA_place":"publisher","intvolume":"       176","scopus_import":"1","isi":1,"external_id":{"isi":["001585783400001"],"arxiv":["2402.01447"]},"OA_type":"hybrid","author":[{"last_name":"Christoph","full_name":"Christoph, Micha","first_name":"Micha"},{"first_name":"Rajko","full_name":"Nenadov, Rajko","last_name":"Nenadov"},{"first_name":"Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","full_name":"Petrova, Kalina H","last_name":"Petrova"}],"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Image 1 Part of this research was conducted while the author was at Department of Computer Science, ETH Zürich, Switzerland. This author was supported by grant no. CRSII5 173721 of the Swiss National Science Foundation.","department":[{"_id":"MaKw"}],"ec_funded":1,"language":[{"iso":"eng"}],"date_updated":"2026-01-05T13:29:52Z","quality_controlled":"1","_id":"20422","date_published":"2026-01-01T00:00:00Z","month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"year":"2026","ddc":["510"],"corr_author":"1","arxiv":1,"page":"254-267","PlanS_conform":"1","status":"public","title":"The Hamilton space of pseudorandom graphs","volume":176},{"publication_identifier":{"issn":["0179-5376"],"eissn":["1432-0444"]},"oa_version":"Published Version","publication":"Discrete and Computational Geometry","file":[{"success":1,"file_name":"2026_DiscreteCompGeom_Biswas.pdf","checksum":"0addb5c1b78142f9fb453bfa04695400","file_id":"20952","creator":"dernst","date_updated":"2026-01-05T13:21:20Z","date_created":"2026-01-05T13:21:20Z","file_size":570922,"access_level":"open_access","relation":"main_file","content_type":"application/pdf"}],"abstract":[{"text":"Given a locally finite set A⊆Rd and a coloring χ:A→{0,1,…,s}, we introduce the chromatic Delaunay mosaic of χ, which is a Delaunay mosaic in Rs+d that represents how points of different colors mingle. Our main results are bounds on the size of the chromatic Delaunay mosaic, in which we assume that d and s are constants. For example, if A is finite with n=#A, and the coloring is random, then the chromatic Delaunay mosaic has O(n⌈d/2⌉) cells in expectation. In contrast, for Delone sets and Poisson point processes in Rd, the expected number of cells within a closed ball is only a constant times the number of points in this ball. Furthermore, in R2 all colorings of a dense set of n points have chromatic Delaunay mosaics of size O(n). This encourages the use of chromatic Delaunay mosaics in applications.","lang":"eng"}],"publication_status":"published","doi":"10.1007/s00454-025-00778-7","date_created":"2025-10-12T22:01:26Z","article_type":"original","publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. 2026;75:24-47. doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>","short":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, M. Saghafian, Discrete and Computational Geometry 75 (2026) 24–47.","chicago":"Biswas, Ranita, Sebastiano Cultrera di Montesano, Ondrej Draganov, Herbert Edelsbrunner, and Morteza Saghafian. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>.","apa":"Biswas, R., Cultrera di Montesano, S., Draganov, O., Edelsbrunner, H., &#38; Saghafian, M. (2026). On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>","ista":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. 2026. On the size of chromatic Delaunay mosaics. Discrete and Computational Geometry. 75, 24–47.","mla":"Biswas, Ranita, et al. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>, vol. 75, Springer Nature, 2026, pp. 24–47, doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>.","ieee":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, and M. Saghafian, “On the size of chromatic Delaunay mosaics,” <i>Discrete and Computational Geometry</i>, vol. 75. Springer Nature, pp. 24–47, 2026."},"type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"intvolume":"        75","day":"01","file_date_updated":"2026-01-05T13:21:20Z","OA_place":"publisher","OA_type":"hybrid","author":[{"full_name":"Biswas, Ranita","last_name":"Biswas","orcid":"0000-0002-5372-7890","id":"3C2B033E-F248-11E8-B48F-1D18A9856A87","first_name":"Ranita"},{"first_name":"Sebastiano","id":"34D2A09C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6249-0832","full_name":"Cultrera di Montesano, Sebastiano","last_name":"Cultrera di Montesano"},{"full_name":"Draganov, Ondrej","last_name":"Draganov","id":"2B23F01E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0464-3823","first_name":"Ondrej"},{"first_name":"Herbert","orcid":"0000-0002-9823-6833","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","first_name":"Morteza","last_name":"Saghafian","full_name":"Saghafian, Morteza"}],"scopus_import":"1","isi":1,"external_id":{"isi":["001584166900001"],"arxiv":["2212.03121"]},"ec_funded":1,"project":[{"grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","name":"Alpha Shape Theory Extended","call_identifier":"H2020"},{"grant_number":"Z00342","name":"Mathematics, Computer Science","_id":"268116B8-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"call_identifier":"FWF","grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","name":"Persistence and stability of geometric complexes"}],"department":[{"_id":"HeEd"}],"acknowledgement":"The fourth author thanks Boris Aronov for insightful discussions on the size of the overlay of Voronoi tessellations. Open access funding provided by Institute of Science and Technology (IST Austria). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme, grant no. 788183, from the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, Austrian Science Fund (FWF), grant no. I 02979-N35.","quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-01-05T13:21:56Z","_id":"20456","date_published":"2026-01-01T00:00:00Z","month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"related_material":{"record":[{"id":"15090","relation":"earlier_version","status":"public"}]},"year":"2026","ddc":["510"],"arxiv":1,"corr_author":"1","page":"24-47","PlanS_conform":"1","status":"public","volume":75,"title":"On the size of chromatic Delaunay mosaics"},{"oa_version":"Published Version","publication_identifier":{"issn":["0195-6698"]},"doi":"10.1016/j.ejc.2025.104235","publication":"European Journal of Combinatorics","file":[{"success":1,"file_name":"2026_EuropJourCombinatorics_Boyadzhiyska.pdf","checksum":"52883daa217398396cbf9b8ad9ddae92","file_id":"20954","creator":"dernst","date_updated":"2026-01-05T13:34:40Z","date_created":"2026-01-05T13:34:40Z","file_size":563029,"access_level":"open_access","content_type":"application/pdf","relation":"main_file"}],"abstract":[{"text":"In his study of graph codes, Alon introduced the concept of the odd-Ramsey number of a family of graphs H in Kn, defined as the minimum number of colours needed to colour the edges of K so that every copy of a graph H E H intersects some colour class in an odd number of edges. In this paper, we focus on complete bipartite graphs. First, we completely resolve the problem when H is the family of all spanning complete bipartite graphs on n vertices. We then focus on its subfamilies, that is, {Kt,n-t : t E T} for a fixed set of integers T c [[n/2]]. We prove that the odd-Ramsey problem is equivalent to determining the maximum dimension of a linear binary code avoiding codewords of given weights, and leverage known results from coding theory to deduce asymptotically tight bounds in our setting. We conclude with bounds for the odd-Ramsey numbers of fixed (that is, non-spanning) complete bipartite subgraphs.","lang":"eng"}],"publication_status":"published","article_type":"original","publisher":"Elsevier","date_created":"2025-10-16T13:14:34Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"citation":{"ieee":"S. Boyadzhiyska, S. Das, T. Lesgourgues, and K. H. Petrova, “Odd-Ramsey numbers of complete bipartite graphs,” <i>European Journal of Combinatorics</i>, vol. 131. Elsevier, 2026.","mla":"Boyadzhiyska, Simona, et al. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>, vol. 131, 104235, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>.","ista":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. 2026. Odd-Ramsey numbers of complete bipartite graphs. European Journal of Combinatorics. 131, 104235.","apa":"Boyadzhiyska, S., Das, S., Lesgourgues, T., &#38; Petrova, K. H. (2026). Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>","chicago":"Boyadzhiyska, Simona, Shagnik Das, Thomas Lesgourgues, and Kalina H Petrova. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>.","short":"S. Boyadzhiyska, S. Das, T. Lesgourgues, K.H. Petrova, European Journal of Combinatorics 131 (2026).","ama":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. 2026;131. doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>"},"day":"01","file_date_updated":"2026-01-05T13:34:40Z","OA_place":"publisher","intvolume":"       131","article_number":"104235","scopus_import":"1","isi":1,"external_id":{"isi":["001573380700001"],"arxiv":["2410.05887"]},"OA_type":"hybrid","author":[{"last_name":"Boyadzhiyska","full_name":"Boyadzhiyska, Simona","first_name":"Simona"},{"first_name":"Shagnik","full_name":"Das, Shagnik","last_name":"Das"},{"first_name":"Thomas","full_name":"Lesgourgues, Thomas","last_name":"Lesgourgues"},{"full_name":"Petrova, Kalina H","last_name":"Petrova","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","first_name":"Kalina H"}],"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"department":[{"_id":"MaKw"}],"acknowledgement":"The authors would like to thank Gilles Zémor for a helpful clarification on [3], Deepak Bal and Patrick Bennett for bringing [25] to their attention, and both referees for several helpful comments.\r\nS.B.: Most of this research was conducted while the author was at the School of Mathematics, University of Birmingham, Birmingham, United Kingdom. The research leading to these results was supported by EPSRC, United Kingdom, grant no. EP/V048287/1 and by ERC Advanced Grants “GeoScape”, no. 882971 and “ERMiD”, no. 101054936. There are no additional data beyond that contained within the main manuscript.\r\nS.D.: Research supported by Taiwan NSTC grants 111-2115-M-002-009-MY2 and 113-2628-M-002-008-MY4.\r\nK.P.: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Parts of this research was conducted while K.P. was at the Department of Computer Science, ETH Zürich, Switzerland, supported by Swiss National Science Foundation, Switzerland , grant no. CRSII5 173721.","ec_funded":1,"date_updated":"2026-01-05T13:34:48Z","language":[{"iso":"eng"}],"quality_controlled":"1","_id":"20482","date_published":"2026-01-01T00:00:00Z","month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["500"],"year":"2026","arxiv":1,"corr_author":"1","PlanS_conform":"1","status":"public","title":"Odd-Ramsey numbers of complete bipartite graphs","volume":131},{"doi":"10.1103/b48p-kw5l","extern":"1","publication_status":"published","abstract":[{"lang":"eng","text":"Magnets with isotropic easy-plane symmetry host Goldstone modes that can be leveraged for efficient\r\nspin transport. Here, we present a time-resolved optical polarimetry technique that allows us to detect and\r\ncharacterize such low-frequency modes, and use it to observe the Goldstone mode in the multi-Q broken helix\r\nphase of EuIn2As2. The strength of our technique comes from the ability to distinguish between nematic and\r\nmagnetization dynamics in order to yield information about the mode structure, in addition to its frequency. We\r\nfind that the nearly uniform spin precession characteristic of a Goldstone mode is realized only when a small\r\nmagnetic field is used to unpin the broken helix from local strain generated during crystal growth. In this regime,\r\nthe mode frequency scales linearly with the applied field due to the ground state C2z symmetry of the broken\r\nhelix. Our work shows how optical polarimetry can be used to study the Goldstone modes of complex magnets."}],"publication":"Physical Review B","researchdata_availability":"yes","publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"American Physical Society","article_type":"original","date_created":"2026-06-22T08:52:01Z","day":"01","intvolume":"       113","das_tickbox":"1","article_processing_charge":"No","type":"journal_article","citation":{"chicago":"Liebman-Peláez, A., S. J. Garratt, Veronika Sunko, Y. Sun, J. R. Soh, D. Prabhakaran, A. T. Boothroyd, and J. Orenstein. “Observation of a Goldstone Mode in the Broken Helix by Time-Resolved Optical Polarimetry.” <i>Physical Review B</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/b48p-kw5l\">https://doi.org/10.1103/b48p-kw5l</a>.","short":"A. Liebman-Peláez, S.J. Garratt, V. Sunko, Y. Sun, J.R. Soh, D. Prabhakaran, A.T. Boothroyd, J. Orenstein, Physical Review B 113 (2026).","ama":"Liebman-Peláez A, Garratt SJ, Sunko V, et al. Observation of a Goldstone mode in the broken helix by time-resolved optical polarimetry. <i>Physical Review B</i>. 2026;113(22). doi:<a href=\"https://doi.org/10.1103/b48p-kw5l\">10.1103/b48p-kw5l</a>","ieee":"A. Liebman-Peláez <i>et al.</i>, “Observation of a Goldstone mode in the broken helix by time-resolved optical polarimetry,” <i>Physical Review B</i>, vol. 113, no. 22. American Physical Society, 2026.","mla":"Liebman-Peláez, A., et al. “Observation of a Goldstone Mode in the Broken Helix by Time-Resolved Optical Polarimetry.” <i>Physical Review B</i>, vol. 113, no. 22, 224401, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/b48p-kw5l\">10.1103/b48p-kw5l</a>.","apa":"Liebman-Peláez, A., Garratt, S. J., Sunko, V., Sun, Y., Soh, J. R., Prabhakaran, D., … Orenstein, J. (2026). Observation of a Goldstone mode in the broken helix by time-resolved optical polarimetry. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/b48p-kw5l\">https://doi.org/10.1103/b48p-kw5l</a>","ista":"Liebman-Peláez A, Garratt SJ, Sunko V, Sun Y, Soh JR, Prabhakaran D, Boothroyd AT, Orenstein J. 2026. Observation of a Goldstone mode in the broken helix by time-resolved optical polarimetry. Physical Review B. 113(22), 224401."},"issue":"22","acknowledgement":"We would like to thank Ehud Altman for helpful discussions. This research was primarily funded by the Quantum\r\nMaterials (KC2202) program under the U.S. Department of\r\nEnergy, Office of Science, Office of Basic Energy Sciences,\r\nMaterials Sciences and Engineering Division under Contract\r\nNo. DE-AC02-05CH11231, which supported the experimental and theoretical work at the Lawrence Berkeley National\r\nLaboratory and UC Berkeley. D.P. and A.T.B. would like to\r\nacknowledge the Engineering and Physical Sciences Research\r\nCouncil, UK and the Oxford- ShanghaiTech collaboration\r\nproject for financial support. J.O. received support from\r\nthe Gordon and Betty Moore Foundation’s EPiQS Initiative\r\nthrough Grant No. GBMF4537 to J.O. at UC Berkeley. V.S.\r\nis supported by the Miller Institute for Basic Research in\r\nScience, UC Berkeley. S.J.G. was supported by the Gordon\r\nand Betty Moore Foundation.","supplementarymaterial":"no","article_number":"224401","author":[{"full_name":"Liebman-Peláez, A.","last_name":"Liebman-Peláez","first_name":"A."},{"full_name":"Garratt, S. J.","last_name":"Garratt","first_name":"S. J."},{"full_name":"Sunko, Veronika","last_name":"Sunko","orcid":"0000-0003-2724-3523","first_name":"Veronika","id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3"},{"last_name":"Sun","full_name":"Sun, Y.","first_name":"Y."},{"first_name":"J. R.","last_name":"Soh","full_name":"Soh, J. R."},{"first_name":"D.","full_name":"Prabhakaran, D.","last_name":"Prabhakaran"},{"first_name":"A. T.","last_name":"Boothroyd","full_name":"Boothroyd, A. T."},{"first_name":"J.","full_name":"Orenstein, J.","last_name":"Orenstein"}],"OA_type":"closed access","dataavailabilitystatement":"The data that support the findings of this article are openly\r\navailable [27 -  https://doi.org/10.7910/dvn/rqp3az], embargo periods may apply.","date_published":"2026-06-01T00:00:00Z","_id":"22116","date_updated":"2026-06-24T09:49:27Z","language":[{"iso":"eng"}],"quality_controlled":"1","year":"2026","month":"06","status":"public","title":"Observation of a Goldstone mode in the broken helix by time-resolved optical polarimetry","volume":113}]
