[{"month":"10","scopus_import":"1","arxiv":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"12662","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","type":"journal_article","corr_author":"1","volume":37,"citation":{"ieee":"P. Súkeník and C. Lampert, “Generalization in multi-objective machine learning,” <i>Neural Computing and Applications</i>, vol. 37. Springer Nature, pp. 24669–24683, 2025.","ama":"Súkeník P, Lampert C. Generalization in multi-objective machine learning. <i>Neural Computing and Applications</i>. 2025;37:24669–24683. doi:<a href=\"https://doi.org/10.1007/s00521-024-10616-1\">10.1007/s00521-024-10616-1</a>","apa":"Súkeník, P., &#38; Lampert, C. (2025). Generalization in multi-objective machine learning. <i>Neural Computing and Applications</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00521-024-10616-1\">https://doi.org/10.1007/s00521-024-10616-1</a>","mla":"Súkeník, Peter, and Christoph Lampert. “Generalization in Multi-Objective Machine Learning.” <i>Neural Computing and Applications</i>, vol. 37, Springer Nature, 2025, pp. 24669–24683, doi:<a href=\"https://doi.org/10.1007/s00521-024-10616-1\">10.1007/s00521-024-10616-1</a>.","chicago":"Súkeník, Peter, and Christoph Lampert. “Generalization in Multi-Objective Machine Learning.” <i>Neural Computing and Applications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00521-024-10616-1\">https://doi.org/10.1007/s00521-024-10616-1</a>.","ista":"Súkeník P, Lampert C. 2025. Generalization in multi-objective machine learning. Neural Computing and Applications. 37, 24669–24683.","short":"P. Súkeník, C. Lampert, Neural Computing and Applications 37 (2025) 24669–24683."},"publication_status":"published","date_published":"2025-10-01T00:00:00Z","doi":"10.1007/s00521-024-10616-1","publisher":"Springer Nature","language":[{"iso":"eng"}],"oa":1,"file":[{"file_id":"20877","access_level":"open_access","checksum":"61ad4591aee16b1e02daf6c164321a42","file_name":"2025_NeuralCompApplic_Sukenik.pdf","date_updated":"2025-12-30T06:39:11Z","content_type":"application/pdf","file_size":500213,"date_created":"2025-12-30T06:39:11Z","creator":"dernst","relation":"main_file","success":1}],"article_type":"original","page":"24669–24683","external_id":{"arxiv":["2208.13499"]},"year":"2025","quality_controlled":"1","day":"01","ddc":["004"],"title":"Generalization in multi-objective machine learning","department":[{"_id":"ChLa"}],"has_accepted_license":"1","OA_type":"hybrid","author":[{"full_name":"Súkeník, Peter","last_name":"Súkeník","id":"d64d6a8d-eb8e-11eb-b029-96fd216dec3c","first_name":"Peter"},{"full_name":"Lampert, Christoph","last_name":"Lampert","orcid":"0000-0001-8622-7887","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph"}],"abstract":[{"text":"Modern machine learning tasks often require considering not just one but multiple objectives. For example, besides the prediction quality, this could be the efficiency, robustness or fairness of the learned models, or any of their combinations. Multi-objective learning offers a natural framework for handling such problems without having to commit to early trade-offs. Surprisingly, statistical learning theory so far offers almost no insight into the generalization properties of multi-objective learning. In this work, we make first steps to fill this gap: We establish foundational generalization bounds for the multi-objective setting as well as generalization and excess bounds for learning with scalarizations. We also provide the first theoretical analysis of the relation between the Pareto-optimal sets of the true objectives and the Pareto-optimal sets of their empirical approximations from training data. In particular, we show a surprising asymmetry: All Pareto-optimal solutions can be approximated by empirically Pareto-optimal ones, but not vice versa.","lang":"eng"}],"date_updated":"2025-12-30T06:39:56Z","intvolume":"        37","oa_version":"Published Version","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).","status":"public","file_date_updated":"2025-12-30T06:39:11Z","date_created":"2023-02-20T08:23:06Z","article_processing_charge":"Yes (via OA deal)","PlanS_conform":"1","publication_identifier":{"eissn":["1433-3058"],"issn":["0941-0643"]},"publication":"Neural Computing and Applications"},{"department":[{"_id":"DaAl"}],"OA_type":"gold","has_accepted_license":"1","ddc":["000"],"day":"01","alternative_title":["PMLR"],"title":"EvoPress: Accurate dynamic model compression via evolutionary search","abstract":[{"text":"The high computational costs of large language models (LLMs) have led to a flurry of research on LLM compression, via methods such as quantization, sparsification, or structured pruning. A new frontier in this area is given by dynamic, non-uniform compression methods, which adjust the compression levels (e.g., sparsity) per-block or even per-layer in order to minimize accuracy loss, while guaranteeing a global compression threshold. Yet, current methods rely on estimating the \"importance\" of a given layer, implicitly assuming that layers contribute independently to the overall compression error. We begin from the motivating observation that this independence assumption does not generally hold for LLM compression: pruning a model further may even significantly recover performance. To address this, we propose EvoPress, a novel evolutionary framework for dynamic LLM compression. By formulating dynamic compression as a general optimization problem, EvoPress identifies optimal compression profiles in a highly efficient manner, and generalizes across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art performance for dynamic compression of Llama, Mistral, and Phi models, setting new benchmarks for structural pruning (block/layer dropping), unstructured sparsity, and quantization with dynamic bitwidths.","lang":"eng"}],"oa_version":"Published Version","date_updated":"2025-12-16T12:34:32Z","intvolume":"       267","author":[{"full_name":"Sieberling, Oliver","last_name":"Sieberling","first_name":"Oliver"},{"last_name":"Kuznedelev","full_name":"Kuznedelev, Denis","first_name":"Denis"},{"full_name":"Kurtic, Eldar","last_name":"Kurtic","first_name":"Eldar","id":"47beb3a5-07b5-11eb-9b87-b108ec578218"},{"last_name":"Alistarh","full_name":"Alistarh, Dan-Adrian","first_name":"Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3650-940X"}],"article_processing_charge":"No","date_created":"2025-12-14T23:02:05Z","status":"public","file_date_updated":"2025-12-16T12:32:40Z","publication":"42nd International Conference on Machine Learning","publication_identifier":{"eissn":["2640-3498"]},"conference":{"start_date":"2025-07-13","location":"Vancouver, Canada","name":"ICML: International Conference on Machine Learning","end_date":"2025-07-19"},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"20820","month":"05","scopus_import":"1","arxiv":1,"corr_author":"1","type":"conference","volume":267,"publication_status":"published","citation":{"short":"O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590.","chicago":"Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In <i>42nd International Conference on Machine Learning</i>, 267:55556–90. ML Research Press, 2025.","mla":"Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 55556–90.","ista":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate dynamic model compression via evolutionary search. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 55556–55590.","ieee":"O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate dynamic model compression via evolutionary search,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.","apa":"Sieberling, O., Kuznedelev, D., Kurtic, E., &#38; Alistarh, D.-A. (2025). EvoPress: Accurate dynamic model compression via evolutionary search. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 55556–55590). Vancouver, Canada: ML Research Press.","ama":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic model compression via evolutionary search. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:55556-55590."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","publisher":"ML Research Press","date_published":"2025-05-01T00:00:00Z","language":[{"iso":"eng"}],"file":[{"file_size":908379,"content_type":"application/pdf","date_updated":"2025-12-16T12:32:40Z","file_name":"2025_ICML_Sieberling.pdf","access_level":"open_access","checksum":"1d744fbaeb199b08e8b6f48bc0dd047e","file_id":"20828","success":1,"creator":"dernst","relation":"main_file","date_created":"2025-12-16T12:32:40Z"}],"oa":1,"quality_controlled":"1","year":"2025","page":"55556-55590","external_id":{"arxiv":["2410.14649"]}},{"ddc":["000"],"alternative_title":["PMLR"],"day":"01","title":"Layer-wise quantization for quantized optimistic dual averaging","department":[{"_id":"DaAl"}],"project":[{"_id":"8e35c14b-16d5-11f0-9cad-a3fc35339161","grant_number":"101158077","name":"FastML: Efficient and Cost-Effective Distributed Machine Learning"}],"OA_type":"gold","has_accepted_license":"1","author":[{"full_name":"Nguyen, Anh Duc","last_name":"Nguyen","first_name":"Anh Duc"},{"full_name":"Markov, Ilia","last_name":"Markov","id":"D0CF4148-C985-11E9-8066-0BDEE5697425","first_name":"Ilia"},{"full_name":"Wu, Frank Zhengqing","last_name":"Wu","first_name":"Frank Zhengqing"},{"last_name":"Ramezani-Kebrya","full_name":"Ramezani-Kebrya, Ali","first_name":"Ali"},{"last_name":"Antonakopoulos","full_name":"Antonakopoulos, Kimon","first_name":"Kimon"},{"orcid":"0000-0003-3650-940X","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","first_name":"Dan-Adrian","full_name":"Alistarh, Dan-Adrian","last_name":"Alistarh"},{"full_name":"Cevher, Volkan","last_name":"Cevher","first_name":"Volkan"}],"abstract":[{"lang":"eng","text":"Modern deep neural networks exhibit heterogeneity across numerous layers of various types such as residuals, multi-head attention, etc., due to varying structures (dimensions, activation functions, etc.), distinct representation characteristics, which impact predictions. We develop a general layer-wise quantization framework with tight variance and code-length bounds, adapting to the heterogeneities over the course of training. We then apply a new layer-wise quantization technique within distributed variational inequalities (VIs), proposing a novel Quantized Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which achieves competitive convergence rates for monotone VIs. We empirically show that QODA achieves up to a 150% speedup over the baselines in end-to-end training time for training Wasserstein GAN on 12+GPUs."}],"oa_version":"Published Version","date_updated":"2025-12-16T12:46:54Z","intvolume":"       267","acknowledgement":"This work was supported by Hasler Foundation Program: Hasler Responsible AI (project number 21043). The research was also sponsored by the Army Research Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011. We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS) for providing computing resources. Dan Alistarh and Ilia Markov were supported in part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian Centre for knowledge-driven machine learning under\r\nproject number 332645 - and its Centre for Research-based Innovation funding scheme (Visual Intelligence under grant no. 309439).","date_created":"2025-12-14T23:02:06Z","status":"public","file_date_updated":"2025-12-16T12:45:41Z","article_processing_charge":"No","publication_identifier":{"eissn":["2640-3498"]},"conference":{"start_date":"2025-07-13","location":"Vancouver, Canada","end_date":"2025-07-19","name":"ICML: International Conference on Machine Learning"},"publication":"42nd International Conference on Machine Learning","month":"05","scopus_import":"1","arxiv":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"20821","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","type":"conference","volume":267,"publication_status":"published","citation":{"short":"A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A. Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 46026–46072.","mla":"Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 46026–72.","chicago":"Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya, Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” In <i>42nd International Conference on Machine Learning</i>, 267:46026–72. ML Research Press, 2025.","ista":"Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 46026–46072.","ieee":"A. D. Nguyen <i>et al.</i>, “Layer-wise quantization for quantized optimistic dual averaging,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 46026–46072.","ama":"Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic dual averaging. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:46026-46072.","apa":"Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos, K., Alistarh, D.-A., &#38; Cevher, V. (2025). Layer-wise quantization for quantized optimistic dual averaging. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press."},"language":[{"iso":"eng"}],"publisher":"ML Research Press","date_published":"2025-05-01T00:00:00Z","file":[{"file_id":"20830","file_name":"2025_ICML_Nguyen.pdf","checksum":"a7edf0e4304171a3e035842b3aab1704","access_level":"open_access","content_type":"application/pdf","date_updated":"2025-12-16T12:45:41Z","file_size":756213,"date_created":"2025-12-16T12:45:41Z","creator":"dernst","relation":"main_file","success":1}],"oa":1,"page":"46026-46072","external_id":{"arxiv":["2505.14371"]},"quality_controlled":"1","year":"2025"},{"article_type":"original","date_published":"2025-11-07T00:00:00Z","publisher":"EMS Press","language":[{"iso":"eng"}],"doi":"10.4171/jfg/177","oa":1,"year":"2025","quality_controlled":"1","_id":"20839","scopus_import":"1","month":"11","corr_author":"1","type":"journal_article","citation":{"mla":"Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” <i>Journal of Fractal Geometry</i>, EMS Press, 2025, doi:<a href=\"https://doi.org/10.4171/jfg/177\">10.4171/jfg/177</a>.","ista":"Helfter M. 2025. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. Journal of Fractal Geometry.","chicago":"Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” <i>Journal of Fractal Geometry</i>. EMS Press, 2025. <a href=\"https://doi.org/10.4171/jfg/177\">https://doi.org/10.4171/jfg/177</a>.","short":"M. Helfter, Journal of Fractal Geometry (2025).","ieee":"M. Helfter, “Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces,” <i>Journal of Fractal Geometry</i>. EMS Press, 2025.","apa":"Helfter, M. (2025). Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. <i>Journal of Fractal Geometry</i>. EMS Press. <a href=\"https://doi.org/10.4171/jfg/177\">https://doi.org/10.4171/jfg/177</a>","ama":"Helfter M. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. <i>Journal of Fractal Geometry</i>. 2025. doi:<a href=\"https://doi.org/10.4171/jfg/177\">10.4171/jfg/177</a>"},"publication_status":"epub_ahead","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","article_processing_charge":"Yes","status":"public","main_file_link":[{"url":"https://doi.org/10.4171/jfg/177","open_access":"1"}],"date_created":"2025-12-19T10:15:37Z","publication":"Journal of Fractal Geometry","publication_identifier":{"eissn":["2308-1317"],"issn":["2308-1309"]},"DOAJ_listed":"1","department":[{"_id":"VaKa"}],"OA_type":"gold","day":"07","ddc":["500"],"title":"Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces","abstract":[{"lang":"eng","text":"For every couple of Hausdorff functions ψ and φ verifying some mild assumptions, there exists a compact subset K of the Baire space such that the φ-Hausdorff measure and the ψ-packing measure on K are both finite and positive. Such examples are then embedded in any infinite dimensional Banach space to answer positively a question of Fan on the existence of metric spaces with arbitrary scales."}],"date_updated":"2026-06-18T18:26:33Z","oa_version":"Published Version","author":[{"first_name":"Mathieu","id":"7d296fbe-e2c6-11ee-84d3-d5c2945f9a57","last_name":"Helfter","full_name":"Helfter, Mathieu"}]},{"year":"2025","related_material":{"record":[{"status":"public","id":"20840","relation":"used_in_publication"}]},"article_processing_charge":"No","status":"public","oa":1,"file_date_updated":"2025-12-22T13:51:09Z","file":[{"relation":"main_file","creator":"sagafono","success":1,"date_created":"2025-12-22T13:45:30Z","content_type":"application/x-zip-compressed","date_updated":"2025-12-22T13:45:30Z","file_size":146656591,"file_id":"20854","file_name":"AllData.zip","checksum":"7af34e4226a00cdcb7f154272050e217","access_level":"open_access"},{"date_updated":"2025-12-22T13:45:33Z","content_type":"application/x-zip-compressed","file_size":93470129,"file_id":"20855","checksum":"71806a2ef9fb26ad7b78e04c6754ee4e","access_level":"open_access","file_name":"SourceData.zip","creator":"sagafono","relation":"main_file","success":1,"date_created":"2025-12-22T13:45:33Z"},{"access_level":"open_access","checksum":"08facd1b4a102f83e4d99d48a85b258d","file_name":"readme.txt","file_id":"20856","file_size":461,"date_updated":"2025-12-22T13:51:09Z","content_type":"text/plain","date_created":"2025-12-22T13:51:09Z","success":1,"creator":"sagafono","relation":"main_file"}],"date_created":"2025-12-21T14:23:50Z","contributor":[{"first_name":"Pere","last_name":"Rosello"},{"first_name":"Manuel","last_name":"Mekonnen"},{"last_name":"Hosten","contributor_type":"supervisor","first_name":"Onur","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2031-204X"}],"publisher":"Institute of Science and Technology Austria","date_published":"2025-12-22T00:00:00Z","doi":"10.15479/AT-ISTA-20842","date_updated":"2026-06-10T08:36:07Z","citation":{"ieee":"S. Agafonova, “Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface.’” Institute of Science and Technology Austria, 2025.","apa":"Agafonova, S. (2025). Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">https://doi.org/10.15479/AT-ISTA-20842</a>","ama":"Agafonova S. Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>","short":"S. Agafonova, (2025).","mla":"Agafonova, Sofia. <i>Research Data for: “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.”</i> Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>.","chicago":"Agafonova, Sofia. “Research Data for: ‘One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.’” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">https://doi.org/10.15479/AT-ISTA-20842</a>.","ista":"Agafonova S. 2025. Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-20842\">10.15479/AT-ISTA-20842</a>."},"oa_version":"Published Version","abstract":[{"text":"Probing the possibility of entanglement generation through gravity offers a path to tackle the question of whether gravitational fields possess a quantum mechanical nature. A potential realization necessitates systems with low-frequency dynamics at an optimal mass scale, for which the microgram-to-milligram range is a strong contender. Here, after refining a figure-of-merit for the problem, we present a 1-milligram torsional pendulum operating at 18 Hz. We demonstrate laser cooling its motion from room temperature to 240~microkelvins, surpassing by over 20-fold the coldest motions attained for oscillators ranging from micrograms to kilograms. We quantify and contrast the utility of the current approach with other platforms. The achieved performance and large improvement potential highlight milligram-scale torsional pendulums as a powerful platform for precision measurements relevant to future studies at the quantum-gravity interface.","lang":"eng"}],"type":"research_data","corr_author":"1","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","author":[{"last_name":"Agafonova","full_name":"Agafonova, Sofya","id":"09501ff6-dca7-11ea-a8ae-b3e0b9166e80","first_name":"Sofya","orcid":"0000-0003-0582-2946"}],"_id":"20842","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","project":[{"name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics","grant_number":"101087907","_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6"}],"department":[{"_id":"GradSch"},{"_id":"OnHo"}],"title":"Research Data for: 'One-milligram torsional pendulum toward experiments at the quantum-gravity interface'","month":"12","day":"22"},{"status":"public","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/1723"}],"date_created":"2025-12-21T23:01:33Z","acknowledgement":"Jesko Dujmovic: Funded by the European Union (ERC, LACONIC, 101041207). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them.\r\nChristoph U. Günther and Krzysztof Pietrzak: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","article_processing_charge":"No","conference":{"name":"TCC: Theory of Cryptography","end_date":"2025-12-05","start_date":"2025-12-01","location":"Aarhus, Denmark"},"publication_identifier":{"isbn":["9783032122896"],"eissn":["1611-3349"],"issn":["0302-9743"]},"publication":"23rd International Conference on Theory of Cryptography","title":"Space-deniable proofs","alternative_title":["LNCS"],"day":"05","OA_type":"green","project":[{"grant_number":"F8509","_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1","name":"Security and Privacy by Design for Complex Systems"}],"department":[{"_id":"KrPi"}],"author":[{"first_name":"Jesko","last_name":"Dujmovic","full_name":"Dujmovic, Jesko"},{"full_name":"Günther, Christoph Ullrich","last_name":"Günther","id":"ec98511c-eb8e-11eb-b029-edd25d7271a1","first_name":"Christoph Ullrich"},{"first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z"}],"intvolume":"     16271","date_updated":"2025-12-29T11:44:16Z","oa_version":"Preprint","abstract":[{"text":"We introduce and construct a new proof system called Non-interactive Arguments of Knowledge or Space (NArKoS), where a space-bounded prover can convince a verifier they know a secret, while having access to sufficient space allows one to forge indistinguishable proofs without the secret.\r\nAn application of NArKoS are space-deniable proofs, which are proofs of knowledge (say for authentication in access control) that are sound when executed by a lightweight device like a smart-card or an RFID chip that cannot have much storage, but are deniable (in the strong sense of online deniability) as the verifier, like a card reader, can efficiently forge such proofs.\r\nWe construct NArKoS in the random oracle model using an OR-proof combining a sigma protocol (for the proof of knowledge of the secret) with a new proof system called simulatable Proof of Transient Space (simPoTS). We give two different constructions of simPoTS, one based on labelling graphs with high pebbling complexity, a technique used in the construction of memory-hard functions and proofs of space, and a more practical construction based on the verifiable space-hard functions from TCC’24 where a prover must compute a root of a sparse polynomial. In both cases, the main challenge is making the proofs efficiently simulatable.","lang":"eng"}],"oa":1,"date_published":"2025-12-05T00:00:00Z","publisher":"Springer Nature","doi":"10.1007/978-3-032-12290-2_6","language":[{"iso":"eng"}],"page":"171-202","year":"2025","quality_controlled":"1","month":"12","scopus_import":"1","_id":"20844","OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Dujmovic J, Günther CU, Pietrzak KZ. Space-deniable proofs. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:171-202. doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">10.1007/978-3-032-12290-2_6</a>","apa":"Dujmovic, J., Günther, C. U., &#38; Pietrzak, K. Z. (2025). Space-deniable proofs. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16271, pp. 171–202). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">https://doi.org/10.1007/978-3-032-12290-2_6</a>","ieee":"J. Dujmovic, C. U. Günther, and K. Z. Pietrzak, “Space-deniable proofs,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16271, pp. 171–202.","short":"J. Dujmovic, C.U. Günther, K.Z. Pietrzak, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 171–202.","chicago":"Dujmovic, Jesko, Christoph Ullrich Günther, and Krzysztof Z Pietrzak. “Space-Deniable Proofs.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:171–202. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">https://doi.org/10.1007/978-3-032-12290-2_6</a>.","mla":"Dujmovic, Jesko, et al. “Space-Deniable Proofs.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 171–202, doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">10.1007/978-3-032-12290-2_6</a>.","ista":"Dujmovic J, Günther CU, Pietrzak KZ. 2025. Space-deniable proofs. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 171–202."},"publication_status":"published","type":"conference","corr_author":"1","volume":16271},{"scopus_import":"1","month":"12","_id":"20845","OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Agrawal S, Modi A, Yadav A, Yamada S. 2025. Zeroizing attacks against evasive and circular evasive LWE. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16269, 259–290.","mla":"Agrawal, Shweta, et al. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16269, Springer Nature, 2025, pp. 259–90, doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>.","chicago":"Agrawal, Shweta, Anuja Modi, Anshu Yadav, and Shota Yamada. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” In <i>23rd International Conference on Theory of Cryptography</i>, 16269:259–90. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>.","short":"S. Agrawal, A. Modi, A. Yadav, S. Yamada, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 259–290.","ieee":"S. Agrawal, A. Modi, A. Yadav, and S. Yamada, “Zeroizing attacks against evasive and circular evasive LWE,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16269, pp. 259–290.","apa":"Agrawal, S., Modi, A., Yadav, A., &#38; Yamada, S. (2025). Zeroizing attacks against evasive and circular evasive LWE. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16269, pp. 259–290). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>","ama":"Agrawal S, Modi A, Yadav A, Yamada S. Zeroizing attacks against evasive and circular evasive LWE. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16269. Springer Nature; 2025:259-290. doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>"},"publication_status":"published","type":"conference","volume":16269,"oa":1,"language":[{"iso":"eng"}],"doi":"10.1007/978-3-032-12293-3_9","date_published":"2025-12-05T00:00:00Z","publisher":"Springer Nature","page":"259-290","year":"2025","quality_controlled":"1","title":"Zeroizing attacks against evasive and circular evasive LWE","day":"05","alternative_title":["LNCS"],"OA_type":"green","department":[{"_id":"KrPi"}],"author":[{"last_name":"Agrawal","full_name":"Agrawal, Shweta","first_name":"Shweta"},{"full_name":"Modi, Anuja","last_name":"Modi","first_name":"Anuja"},{"full_name":"Yadav, Anshu","last_name":"Yadav","first_name":"Anshu","id":"dc8f1524-403e-11ee-bf07-9649ad996e21"},{"first_name":"Shota","last_name":"Yamada","full_name":"Yamada, Shota"}],"date_updated":"2025-12-29T11:51:13Z","intvolume":"     16269","oa_version":"Preprint","abstract":[{"lang":"eng","text":"We develop new attacks against the Evasive LWE family of assumptions, in both the public and private-coin regime. To the best of our knowledge, ours are the first attacks against Evasive LWE in the public-coin regime, for any instantiation from the family. Our attacks are summarized below.\r\n\r\nPublic-Coin Attacks.\r\n1.The recent work by Hseih, Lin and Luo [17] constructed the first Attribute Based Encryption (ABE) for unbounded depth circuits by relying on the “circular” evasive LWE assumption. This assumption has been popularly considered as a safe, public-coin instance of Evasive LWE in contrast to its “private-coin” cousins (for instance, see [10, 11]).\r\nWe provide the first attack against this assumption, challenging the widely held belief that this is a public-coin assumption.\r\n2. We demonstrate a counter-example against vanilla public-coin evasive LWE by Wee [26] in an unnatural parameter regime. Our attack crucially relies on the error in the pre-condition being larger than the error in the post-condition, necessitating a refinement of the assumption.\r\n\r\nPrivate-Coin Attacks.\r\n1. The recent work by Agrawal, Kumari and Yamada [2] constructed the first functional encryption scheme for pseudorandom functionalities (PRFE) and extended this to obfuscation for pseudorandom functionalities (PRIO) [4] by relying on private-coin evasive LWE. We provide a new attack against the assumption stated in the first posting of their work (subsequently refined to avoid these attacks).\r\n2. The recent work by Branco et al. [8] (concurrently to [4]) provides a construction of obfuscation for pseudorandom functionalities by relying on private-coin evasive LWE. We provide a new attack against their stated assumption.\r\n3. Branco et al. [8] showed that there exist contrived, “self-referential” classes of pseudorandom functionalities for which pseudorandom obfuscation cannot exist. We extend their techniques to develop an analogous result for pseudorandom functional encryption.\r\n\r\nWhile Evasive LWE was developed to specifically avoid “zeroizing attacks”, our work shows that in certain settings, such attacks can still apply."}],"status":"public","main_file_link":[{"url":"https://eprint.iacr.org/2025/375","open_access":"1"}],"date_created":"2025-12-21T23:01:33Z","acknowledgement":"We thank Rachel Lin for expressing concern about the applicability of “HJL-style” attacks [15] on the construction in [2] during a talk by the first author about [2]. This was the starting point of the investigation that led us to develop the attack in [5, Sec 4.1]. The first author also thanks Hoeteck Wee for sharing his rationale for introducing evasive LWE.\r\nThe first author is supported by the CyStar center of excellence, the VHAR faculty chair, and the C3iHub fellowship. The third author thanks Cystar, IIT Madras, for supporting a visit to IIT Madras during which the collaboration was initiated. The 4th author is partly supported by JST CREST Grant Number JPMJCR22M1.","article_processing_charge":"No","conference":{"end_date":"2025-12-05","name":"TCC: Theory of Cryptography","location":"Aarhus, Denmark","start_date":"2025-12-01"},"publication_identifier":{"isbn":["9783032122926"],"eissn":["1611-3349"],"issn":["0302-9743"]},"publication":"23rd International Conference on Theory of Cryptography"},{"article_processing_charge":"No","acknowledgement":"We thank Jonas Steinbach and Gertjan De Mulder for helpful discussions on BIP 32, Dennis Hofheinz and Julia Kastner for helpful discussions on early prototypes of our CVRF, and Klaus Kraßnitzer for running pairing benchmarks on his MacBook Pro.\r\nChristoph U. Günther: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","status":"public","date_created":"2025-12-21T23:01:34Z","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/1045"}],"publication":"23rd International Conference on Theory of Cryptography","publication_identifier":{"isbn":["9783032122896"],"eissn":["1611-3349"],"issn":["0302-9743"]},"conference":{"start_date":"2025-12-01","location":"Aarhus, Denmark","name":"TCC: Theory of Cryptography","end_date":"2025-12-05"},"project":[{"_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1","grant_number":"F8509","name":"Security and Privacy by Design for Complex Systems"}],"department":[{"_id":"KrPi"}],"OA_type":"green","day":"05","alternative_title":["LNCS"],"title":"Constrained verifiable random functions without obfuscation and friends","abstract":[{"lang":"eng","text":"CVRFs are PRFs that unify the properties of verifiable and constrained PRFs. Since they were introduced concurrently by Fuchsbauer and Chandran-Raghuraman-Vinayagamurthy in 2014, it has been an open problem to construct CVRFs without using heavy machinery such as multilinear maps, obfuscation or functional encryption.\r\nWe solve this problem by constructing a prefix-constrained verifiable PRF that does not rely on the aforementioned assumptions. Essentially, our construction is a verifiable version of the Goldreich-Goldwasser-Micali PRF. To achieve verifiability we leverage degree-2 algebraic PRGs and bilinear groups. In short, proofs consist of intermediate values of the Goldreich-Goldwasser-Micali PRF raised to the exponents of group elements. These outputs can be verified using pairings since the underlying PRG is of degree 2.\r\nWe prove the selective security of our construction under the Decisional Square Diffie-Hellman (DSDH) assumption and a new assumption, which we dub recursive Decisional Diffie-Hellman (recursive DDH).\r\nWe prove the soundness of recursive DDH in the generic group model assuming the hardness of the Multivariate Quadratic (MQ) problem and a new variant thereof, which we call MQ+.\r\nLast, in terms of applications, we observe that our CVRF is also an exponent (C)VRF in the plain model. Exponent VRFs were recently introduced by Boneh et al. (Eurocrypt’25) with various applications to threshold cryptography in mind. In addition to that, we give further applications for prefix-CVRFs in the blockchain setting, namely, stake-pooling and compressible randomness beacons."}],"date_updated":"2025-12-29T11:11:29Z","intvolume":"     16271","oa_version":"Preprint","author":[{"first_name":"Nicholas","last_name":"Brandt","full_name":"Brandt, Nicholas"},{"full_name":"Cueto Noval, Miguel","last_name":"Cueto Noval","orcid":"0000-0002-2505-4246","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc","first_name":"Miguel"},{"id":"ec98511c-eb8e-11eb-b029-edd25d7271a1","first_name":"Christoph Ullrich","last_name":"Günther","full_name":"Günther, Christoph Ullrich"},{"first_name":"Akin","id":"f6b56fb6-dc63-11ee-9dbf-f6780863a85a","orcid":"0000-0002-8929-0221","last_name":"Ünal","full_name":"Ünal, Akin"},{"first_name":"Stella","full_name":"Wohnig, Stella","last_name":"Wohnig"}],"date_published":"2025-12-05T00:00:00Z","doi":"10.1007/978-3-032-12290-2_16","language":[{"iso":"eng"}],"publisher":"Springer Nature","oa":1,"year":"2025","quality_controlled":"1","page":"478-511","_id":"20846","scopus_import":"1","month":"12","type":"conference","corr_author":"1","volume":16271,"citation":{"mla":"Brandt, Nicholas, et al. “Constrained Verifiable Random Functions without Obfuscation and Friends.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 478–511, doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>.","ista":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. 2025. Constrained verifiable random functions without obfuscation and friends. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 478–511.","chicago":"Brandt, Nicholas, Miguel Cueto Noval, Christoph Ullrich Günther, Akin Ünal, and Stella Wohnig. “Constrained Verifiable Random Functions without Obfuscation and Friends.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:478–511. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>.","short":"N. Brandt, M. Cueto Noval, C.U. Günther, A. Ünal, S. Wohnig, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 478–511.","ama":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. Constrained verifiable random functions without obfuscation and friends. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:478-511. doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>","apa":"Brandt, N., Cueto Noval, M., Günther, C. U., Ünal, A., &#38; Wohnig, S. (2025). Constrained verifiable random functions without obfuscation and friends. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16271, pp. 478–511). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>","ieee":"N. Brandt, M. Cueto Noval, C. U. Günther, A. Ünal, and S. Wohnig, “Constrained verifiable random functions without obfuscation and friends,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16271, pp. 478–511."},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"repository"},{"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"publication":"Physical Review E","ec_funded":1,"publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"PlanS_conform":"1","article_processing_charge":"Yes (via OA deal)","date_created":"2025-12-21T23:01:34Z","status":"public","file_date_updated":"2025-12-29T11:15:42Z","acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant\r\nAgreement No. 949120). This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge the crucial contributions of Alexandre Morin in getting the project off the ground, and Jack Merrin for creating the SU-8 deposition protocol used in the construction of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their work on single-particle characterization. ","oa_version":"Published Version","article_number":"065418","intvolume":"       112","date_updated":"2025-12-29T11:19:34Z","abstract":[{"text":"We report on an experimental active matter system with motion restricted to four cardinal directions. Our particles are magnetite-doped colloidal spheres driven by the Quincke electrorotational instability. The absence of a magnetic field (|𝑩|=0) leads to circular trajectories interspersed with short spontaneous runs. Intermediate fields (|𝑩|≲20mT) linearize the motion along the axis perpendicular to 𝑩. At high magnetic fields, we observe the surprising emergence of a second, distinct linearization along the axis parallel to 𝑩. With numerical simulations, we show that this behavior can be explained by anisotropic magnetic susceptibility.","lang":"eng"}],"author":[{"last_name":"Fitzgerald","full_name":"Fitzgerald, Eavan","id":"2df8ab8f-080d-11ed-979a-bfe651ca3afa","first_name":"Eavan"},{"first_name":"Cécile","id":"5f654c5d-04a1-11eb-ab36-ba9ffec58bd8","orcid":"0000-0002-1843-3803","last_name":"Clavaud","full_name":"Clavaud, Cécile"},{"full_name":"Das, Debasish","last_name":"Das","first_name":"Debasish"},{"full_name":"Lenton, Isaac C","last_name":"Lenton","orcid":"0000-0002-5010-6984","first_name":"Isaac C","id":"a550210f-223c-11ec-8182-e2d45e817efb"},{"orcid":"0000-0002-2299-3176","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","full_name":"Waitukaitis, Scott R","last_name":"Waitukaitis"}],"has_accepted_license":"1","OA_type":"hybrid","department":[{"_id":"ScWa"}],"project":[{"grant_number":"E 298","_id":"bd8eede5-d553-11ed-ba76-eaded0d13485","name":"MixQUIckR: Mixing with QUIncke Rollers"},{"call_identifier":"H2020","grant_number":"949120","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","name":"Tribocharge: a multi-scale approach to an enduring problem in physics"}],"title":"Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter","ddc":["530"],"day":"01","quality_controlled":"1","year":"2025","external_id":{"arxiv":["2508.05643"]},"article_type":"original","file":[{"success":1,"creator":"dernst","relation":"main_file","date_created":"2025-12-29T11:15:42Z","file_size":2131491,"date_updated":"2025-12-29T11:15:42Z","content_type":"application/pdf","checksum":"d593e933f976c3f3cde37ad66539d57d","access_level":"open_access","file_name":"2025_PhysReviewE_Fitzgerald.pdf","file_id":"20862"}],"oa":1,"language":[{"iso":"eng"}],"date_published":"2025-12-01T00:00:00Z","doi":"10.1103/1ss8-31rb","publisher":"American Physical Society","issue":"6","publication_status":"published","citation":{"short":"E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical Review E 112 (2025).","chicago":"Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>.","ista":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 112(6), 065418.","mla":"Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>, vol. 112, no. 6, 065418, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>.","ieee":"E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter,” <i>Physical Review E</i>, vol. 112, no. 6. American Physical Society, 2025.","ama":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. 2025;112(6). doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>","apa":"Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., &#38; Waitukaitis, S. R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>"},"corr_author":"1","volume":112,"type":"journal_article","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20847","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"arxiv":1,"scopus_import":"1","month":"12"},{"has_accepted_license":"1","OA_type":"hybrid","department":[{"_id":"NiBa"}],"title":"Mutation–selection–drift balance models of complex diseases","ddc":["570"],"day":"01","article_number":"iyaf220","oa_version":"Published Version","intvolume":"       231","date_updated":"2025-12-29T11:29:16Z","abstract":[{"lang":"eng","text":"Genetic variation that influences complex disease susceptibility is introduced into the population by mutation and removed by natural selection and genetic drift. This mutation–selection–drift balance (MSDB) shapes the prevalence of a disease and its genetic architecture. To date, however, MSDB has been modeled only for monogenic (Mendelian) diseases. Here, we develop an MSDB model for complex disease susceptibility: we assume that genotype relates to disease risk according to the canonical liability threshold model and that the selection on variants affecting risk stems from the fitness cost of the disease. We focus on diseases that are highly polygenic, entail a substantial fitness cost, and are neither extremely common in the population nor exceedingly rare. The comparison of model predictions with genome-wide association studies and other observations in humans indicates that common genetic variation affecting complex disease susceptibility is little affected by directional selection and instead shaped by pleiotropic stabilizing selection on other traits. In turn, directional selection may exert a more substantial effect on rare, large-effect variants. Our results also suggest that current estimates of disease heritability are likely biased. The model thus provides a better understanding of the evolutionary processes that shape the architecture and prevalence of complex diseases."}],"author":[{"last_name":"Berg","full_name":"Berg, Jeremy J.","first_name":"Jeremy J."},{"first_name":"Xinyi","full_name":"Li, Xinyi","last_name":"Li"},{"first_name":"Kellen","full_name":"Riall, Kellen","last_name":"Riall"},{"first_name":"Laura","id":"fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b","last_name":"Hayward","full_name":"Hayward, Laura"},{"first_name":"Guy","full_name":"Sella, Guy","last_name":"Sella"}],"article_processing_charge":"Yes (in subscription journal)","date_created":"2025-12-21T23:01:34Z","status":"public","file_date_updated":"2025-12-29T11:27:51Z","acknowledgement":"We thank Nick Barton, Magnus Nordborg, John Novembre, Molly Przeworski, and Himani Sachdeva for many helpful discussions and for comments on the manuscript, and we thank Joshua Schraiber and 2 anonymous reviewers for comments on the manuscript. We also thank members of the Sella, Przeworski and Andolfatto labs at Columbia University, and the Berg, Novembre and Steinrücken labs at the University of Chicago, for feedback on the work at various stages. This work was completed in part with resources provided by the University of Chicago's Research Computing Center. This work was supported by National Institutes of Health F32 grant GM126787 and R35 grant GM151257 to J.J.B. and National Institutes of Health R01 grant GM115889 to G.S.","publication":"Genetics","publication_identifier":{"eissn":["1943-2631"],"issn":["0016-6731"]},"_id":"20848","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"pmid":1,"month":"12","scopus_import":"1","publication_status":"published","citation":{"ista":"Berg JJ, Li X, Riall K, Hayward L, Sella G. 2025. Mutation–selection–drift balance models of complex diseases. Genetics. 231(4), iyaf220.","chicago":"Berg, Jeremy J., Xinyi Li, Kellen Riall, Laura Hayward, and Guy Sella. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>.","mla":"Berg, Jeremy J., et al. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>, vol. 231, no. 4, iyaf220, Oxford University Press, 2025, doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>.","short":"J.J. Berg, X. Li, K. Riall, L. Hayward, G. Sella, Genetics 231 (2025).","ama":"Berg JJ, Li X, Riall K, Hayward L, Sella G. Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. 2025;231(4). doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>","apa":"Berg, J. J., Li, X., Riall, K., Hayward, L., &#38; Sella, G. (2025). Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>","ieee":"J. J. Berg, X. Li, K. Riall, L. Hayward, and G. Sella, “Mutation–selection–drift balance models of complex diseases,” <i>Genetics</i>, vol. 231, no. 4. Oxford University Press, 2025."},"type":"journal_article","volume":231,"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","file":[{"date_updated":"2025-12-29T11:27:51Z","content_type":"application/pdf","file_size":1182339,"file_id":"20863","checksum":"b02eb6b78028b8bef435edc8435a8468","access_level":"open_access","file_name":"2025_Genetics_Berg.pdf","relation":"main_file","creator":"dernst","success":1,"date_created":"2025-12-29T11:27:51Z"}],"oa":1,"publisher":"Oxford University Press","doi":"10.1093/genetics/iyaf220","language":[{"iso":"eng"}],"date_published":"2025-12-01T00:00:00Z","issue":"4","quality_controlled":"1","year":"2025","external_id":{"pmid":["41073879"]}},{"article_processing_charge":"Yes (in subscription journal)","file_date_updated":"2025-12-29T10:05:22Z","status":"public","date_created":"2025-12-21T23:01:35Z","acknowledgement":"The author would like to thank his supervisor Tim Browning for suggesting this project and many helpful conversations and useful comments. Moreover, he is grateful to Jakob Glas, Damaris Schindler, Igor Shparlinski, Matteo Verzobio, Victor Wang, Florian Wilsch and Shuntaro Yamagishi for taking their time to answer his questions and their valuable suggestions.","publication":"Journal de theorie des nombres de Bordeaux","publication_identifier":{"eissn":["2118-8572"],"issn":["1246-7405"]},"has_accepted_license":"1","OA_type":"hybrid","department":[{"_id":"TiBr"}],"title":"Class numbers and integer points on some Pellian surfaces","day":"27","ddc":["510"],"intvolume":"        37","date_updated":"2025-12-29T10:08:46Z","oa_version":"Published Version","abstract":[{"lang":"eng","text":"We provide an estimate for the number of nontrivial integer points on the Pellian surface t^2 - du^2 = 1 in a bounded region. We give a lower bound on the size of fundamental solutions for almost all d in a certain class, based on a recent conjecture of Browning and Wilsch about integer points on log K3 surfaces. We also obtain an upper bound on the average of class number in this class, assuming the same conjecture."},{"text":"Nous donnons une estimation du nombre de points entiers non triviaux sur la surface pellienne \r\nt^2 - du^2 = 1 dans une région bornée. Nous établissons une borne inférieure pour la taille des solutions fondamentales pour presque tout d appartenant à une certaine classe, en nous fondant sur une conjecture récente de Browning et Wilsch concernant les points entiers sur les surfaces log K3. Nous obtenons également une borne supérieure pour la moyenne du nombre de classes dans cette classe, sous la même hypothèse conjecturale.","lang":"fre"}],"license":"https://creativecommons.org/licenses/by-nd/4.0/","author":[{"last_name":"Diao","full_name":"Diao, Yijie","id":"7b7eb4ca-eb2c-11ec-b98b-accec0b20c3b","first_name":"Yijie","orcid":"0000-0002-4989-5330"}],"article_type":"original","oa":1,"file":[{"date_created":"2025-12-29T10:05:22Z","success":1,"relation":"main_file","creator":"dernst","access_level":"open_access","checksum":"67aa0afbc0b5bcbff5341f4d25e6ba20","file_name":"2025_JTNB_Diao.pdf","file_id":"20861","file_size":766196,"date_updated":"2025-12-29T10:05:22Z","content_type":"application/pdf"}],"issue":"3","publisher":"Université de Bordeaux","date_published":"2025-11-27T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.5802/jtnb.1348","year":"2025","quality_controlled":"1","external_id":{"arxiv":["2408.03774"]},"page":"973-988","tmp":{"short":"CC BY-ND (4.0)","name":"Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nd/4.0/legalcode","image":"/image/cc_by_nd.png"},"_id":"20850","arxiv":1,"scopus_import":"1","month":"11","citation":{"ieee":"Y. Diao, “Class numbers and integer points on some Pellian surfaces,” <i>Journal de theorie des nombres de Bordeaux</i>, vol. 37, no. 3. Université de Bordeaux, pp. 973–988, 2025.","ama":"Diao Y. Class numbers and integer points on some Pellian surfaces. <i>Journal de theorie des nombres de Bordeaux</i>. 2025;37(3):973-988. doi:<a href=\"https://doi.org/10.5802/jtnb.1348\">10.5802/jtnb.1348</a>","apa":"Diao, Y. (2025). Class numbers and integer points on some Pellian surfaces. <i>Journal de Theorie Des Nombres de Bordeaux</i>. Université de Bordeaux. <a href=\"https://doi.org/10.5802/jtnb.1348\">https://doi.org/10.5802/jtnb.1348</a>","mla":"Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.” <i>Journal de Theorie Des Nombres de Bordeaux</i>, vol. 37, no. 3, Université de Bordeaux, 2025, pp. 973–88, doi:<a href=\"https://doi.org/10.5802/jtnb.1348\">10.5802/jtnb.1348</a>.","chicago":"Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.” <i>Journal de Theorie Des Nombres de Bordeaux</i>. Université de Bordeaux, 2025. <a href=\"https://doi.org/10.5802/jtnb.1348\">https://doi.org/10.5802/jtnb.1348</a>.","ista":"Diao Y. 2025. Class numbers and integer points on some Pellian surfaces. Journal de theorie des nombres de Bordeaux. 37(3), 973–988.","short":"Y. Diao, Journal de Theorie Des Nombres de Bordeaux 37 (2025) 973–988."},"publication_status":"published","corr_author":"1","volume":37,"type":"journal_article","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. 2025. doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>","apa":"Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot, A. (2025). Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. Wiley. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>","ieee":"X. Chang <i>et al.</i>, “Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications,” <i>Advanced Science</i>. Wiley, 2025.","mla":"Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>, e15962, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>.","ista":"Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez M, Biendicho JJ, Cabot A. 2025. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science., e15962.","chicago":"Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez, Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>.","short":"X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca, M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science (2025)."},"publication_status":"epub_ahead","type":"journal_article","scopus_import":"1","month":"12","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"20851","year":"2025","quality_controlled":"1","doi":"10.1002/advs.202515962","language":[{"iso":"eng"}],"publisher":"Wiley","date_published":"2025-12-12T00:00:00Z","article_type":"original","author":[{"first_name":"Xingqi","full_name":"Chang, Xingqi","last_name":"Chang"},{"last_name":"Escudero","full_name":"Escudero, Carlos","first_name":"Carlos"},{"first_name":"Ashley P.","full_name":"Black, Ashley P.","last_name":"Black"},{"full_name":"Horta, Sharona","last_name":"Horta","first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc"},{"last_name":"Martínez","full_name":"Martínez, Elías","first_name":"Elías"},{"full_name":"Lu, Xuan","last_name":"Lu","first_name":"Xuan"},{"first_name":"Jordi","full_name":"Llorca, Jordi","last_name":"Llorca"},{"full_name":"Ibáñez, Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria"},{"first_name":"Jordi Jacas","full_name":"Biendicho, Jordi Jacas","last_name":"Biendicho"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"}],"date_updated":"2025-12-29T10:15:43Z","oa_version":"Published Version","article_number":"e15962","abstract":[{"text":"High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material for high power density in lithium-ion batteries. However, it suffers from poor cycle life associated with the rock-salt phase transformation. This study presents a straightforward synthesis approach to enhance the electrochemical performance of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4, and, more importantly, effectively mitigates the formation of the rock-salt phase, thereby enhancing structural stability, as confirmed by operando X-ray absorption spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C, 2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode and a high-loading cathode exhibit excellent cycling performance. They retain 80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9 V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and thereby enhancing their potential for practical applications.","lang":"eng"}],"title":"Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications","day":"12","ddc":["540"],"has_accepted_license":"1","OA_type":"gold","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"department":[{"_id":"MaIb"}],"DOAJ_listed":"1","publication_identifier":{"eissn":["2198-3844"]},"publication":"Advanced Science","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"status":"public","date_created":"2025-12-21T23:01:35Z","acknowledgement":"This work was supported by the European Commission-financed project IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This research was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033 and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.","article_processing_charge":"Yes","PlanS_conform":"1"},{"article_processing_charge":"Yes (in subscription journal)","status":"public","file_date_updated":"2025-12-29T09:36:50Z","date_created":"2025-12-28T23:01:26Z","acknowledgement":"J.S. and K.C. were supported by the European Research Council CoG 863818 (ForM-SMArt) and Austrian Science Fund (FWF) 10.55776/COE12.","publication":"Proceedings of the National Academy of Sciences","ec_funded":1,"publication_identifier":{"eissn":["1091-6490"]},"OA_type":"hybrid","has_accepted_license":"1","project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","grant_number":"863818","call_identifier":"H2020"}],"department":[{"_id":"KrCh"}],"title":"Promoters of cooperation in evolutionary games","day":"15","ddc":["000"],"intvolume":"       122","date_updated":"2026-05-20T08:13:17Z","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Evolutionary games provide a flexible mathematical framework for many problems in biology and social evolution. Prisoners’ dilemma, and in particular, the important special case of donation games, represents social dilemmas where cooperation is mutually beneficial, yet defection is preferred by selfish agents. In evolutionary games on networks, the agents interact over a population structure. The existence of population structures that promote cooperative behavior is a fascinating and active research topic. Previous research establishes structures promoting cooperation in the limit of weak selection where the benefit-to-cost ratio β exceeds 1.5. The existence of such structures for medium and strong selection for 1 < ß < 2 and for weak selection for 1 < ß < 1.5 has been a long-standing open question. First, we answer the open questions in the affirmative: For every selection strength and every ß > 1, we construct networks promoting cooperation. Second, we present a robustness result with respect to β and selection strength: Our structures promote cooperation for a range of these parameter values rather than specific parameter values. Finally, we supplement our theoretical results with simulation results on small population structures that show the effectiveness of our construction over well-studied population structures."}],"author":[{"full_name":"Svoboda, Jakub","last_name":"Svoboda","orcid":"0000-0002-1419-3267","first_name":"Jakub","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425"},{"orcid":"0000-0002-4561-241X","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu","full_name":"Chatterjee, Krishnendu","last_name":"Chatterjee"}],"article_type":"original","oa":1,"file":[{"relation":"main_file","creator":"dernst","success":1,"date_created":"2025-12-29T09:36:50Z","content_type":"application/pdf","date_updated":"2025-12-29T09:36:50Z","file_size":2308124,"file_id":"20860","file_name":"2025_PNAS_Svoboda.pdf","checksum":"dd50b62a1efc28c0133fe9c11dbee53c","access_level":"open_access"}],"APC_amount":"3003,56 EUR","issue":"51","publisher":"National Academy of Sciences","date_published":"2025-12-15T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1073/pnas.2524109122","year":"2025","quality_controlled":"1","external_id":{"pmid":["41397136"]},"page":"e2524109122","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"_id":"20857","month":"12","scopus_import":"1","pmid":1,"citation":{"ista":"Svoboda J, Chatterjee K. 2025. Promoters of cooperation in evolutionary games. Proceedings of the National Academy of Sciences. 122(51), e2524109122.","chicago":"Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2524109122\">https://doi.org/10.1073/pnas.2524109122</a>.","mla":"Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 51, National Academy of Sciences, 2025, p. e2524109122, doi:<a href=\"https://doi.org/10.1073/pnas.2524109122\">10.1073/pnas.2524109122</a>.","short":"J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences 122 (2025) e2524109122.","apa":"Svoboda, J., &#38; Chatterjee, K. (2025). Promoters of cooperation in evolutionary games. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2524109122\">https://doi.org/10.1073/pnas.2524109122</a>","ama":"Svoboda J, Chatterjee K. Promoters of cooperation in evolutionary games. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(51):e2524109122. doi:<a href=\"https://doi.org/10.1073/pnas.2524109122\">10.1073/pnas.2524109122</a>","ieee":"J. Svoboda and K. Chatterjee, “Promoters of cooperation in evolutionary games,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 51. National Academy of Sciences, p. e2524109122, 2025."},"publication_status":"published","corr_author":"1","type":"journal_article","volume":122,"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"article_processing_charge":"No","status":"public","date_created":"2025-12-28T23:01:26Z","main_file_link":[{"url":"https://doi.org/10.1101/2025.05.05.652195","open_access":"1"}],"acknowledgement":"This project was generously supported by Seedfinancing (grant no. P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation, und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science and Technology Austria for his continuous technical support.","publication":"Molecular Therapy","publication_identifier":{"eissn":["1525-0024"],"issn":["1525-0016"]},"OA_type":"green","department":[{"_id":"PreCl"}],"title":"Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response","day":"04","date_updated":"2025-12-29T09:55:05Z","oa_version":"Preprint","abstract":[{"lang":"eng","text":"Targeted antigen delivery to immune cells, particularly dendritic cells, has emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while minimizing adverse effects associated with conventional immunization. In this study, we use our previously described small glycomimetic molecule that is selectively recognized by the Langerhans cell (LC)-specific surface receptor Langerin and demonstrate specific delivery of protein antigens to these specialized dendritic cells. Our results show that Langerin-mediated antigen delivery significantly enhances the immune response in vivo, resulting in increased expansion and activation of antigen-specific T cells, compared to immunization with unmodified antigen. We demonstrate the feasibility of our LC-targeted platform for immune cell-specific immunization with protein antigen and underscore the potential of LCs as an access point for next-generation vaccines and immunotherapies."}],"author":[{"full_name":"Rica, Ramona","last_name":"Rica","first_name":"Ramona"},{"full_name":"Klein, Klara","last_name":"Klein","first_name":"Klara"},{"first_name":"Litty","last_name":"Johnson","full_name":"Johnson, Litty"},{"first_name":"Gabriele","last_name":"Carta","full_name":"Carta, Gabriele"},{"first_name":"Mirza","last_name":"Sarcevic","full_name":"Sarcevic, Mirza"},{"id":"3C1BE782-F248-11E8-B48F-1D18A9856A87","first_name":"Freyja","last_name":"Langer","full_name":"Langer, Freyja"},{"first_name":"Christoph","last_name":"Rademacher","full_name":"Rademacher, Christoph"},{"first_name":"Robert","last_name":"Wawrzinek","full_name":"Wawrzinek, Robert"},{"full_name":"Quattrone, Federica","last_name":"Quattrone","first_name":"Federica"},{"full_name":"Sparber, Florian","last_name":"Sparber","first_name":"Florian"}],"article_type":"original","oa":1,"date_published":"2025-10-04T00:00:00Z","publisher":"Elsevier","language":[{"iso":"eng"}],"doi":"10.1016/j.ymthe.2025.10.008","year":"2025","quality_controlled":"1","_id":"20858","month":"10","scopus_import":"1","citation":{"apa":"Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber, F. (n.d.). Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. <i>Molecular Therapy</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">https://doi.org/10.1016/j.ymthe.2025.10.008</a>","ama":"Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. <i>Molecular Therapy</i>. doi:<a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">10.1016/j.ymthe.2025.10.008</a>","ieee":"R. Rica <i>et al.</i>, “Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response,” <i>Molecular Therapy</i>. Elsevier.","short":"R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy (n.d.).","ista":"Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy.","chicago":"Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic, Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” <i>Molecular Therapy</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">https://doi.org/10.1016/j.ymthe.2025.10.008</a>.","mla":"Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” <i>Molecular Therapy</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">10.1016/j.ymthe.2025.10.008</a>."},"publication_status":"inpress","type":"journal_article","OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"acknowledgement":"The authors would like to acknowledge the Super Resolution Light Microcopy and Nanoscopy (SLN) Facility of ICFO for their support with imaging experiments, Johann Osmond (Nanofabrication laboratory, ICFO) for the design and production of molds for generating confinement coverslip, Merche Rivas for cell culture of immune cells and further support from the CRG Core Facilities for Genomics and Advanced Light Microscopy. We would like to thank Michael Sixt for discussions on this work and the Quidant, Ruprecht, and Wieser lab members for critical reading of the manuscript. This research was supported by the Scientific Service Units (SSU) of IST-Austria through resources provided by the Nanofabrication Facility (NFF). C.A. acknowledges the funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 847517 and V.V. from the ICFOstepstone – PhD Programme funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 665884. S.W. acknowledges support through the Spanish Ministry of Economy and Competitiveness via MINECO’s Plan Nacional (BFU2017-86296-P). V.R. acknowledges funding from the European Union’s HORIZON-EIC-2021-PATHFINDEROPEN program under grant agreement no. 101046620 and European Union's Horizon Europe program under the grant agreement no. 101072123. E.K. acknowledges funding by a fellowship of the Ministry of Innovation, Science and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2151 – 390873048 and by the TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments.","status":"public","date_created":"2025-12-28T23:01:27Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.devcel.2025.10.006"}],"article_processing_charge":"Yes (in subscription journal)","PlanS_conform":"1","publication_identifier":{"eissn":["1878-1551"],"issn":["1534-5807"]},"acknowledged_ssus":[{"_id":"NanoFab"}],"publication":"Developmental Cell","day":"04","ddc":["570"],"title":"Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses","department":[{"_id":"Bio"},{"_id":"NanoFab"}],"has_accepted_license":"1","OA_type":"hybrid","author":[{"full_name":"Company-Garrido, Iván","last_name":"Company-Garrido","first_name":"Iván"},{"first_name":"Alberto","full_name":"Zurita Carpio, Alberto","last_name":"Zurita Carpio"},{"full_name":"Colomer-Rosell, Mariona","last_name":"Colomer-Rosell","first_name":"Mariona"},{"first_name":"Bernard","full_name":"Ciraulo, Bernard","last_name":"Ciraulo"},{"first_name":"Ronja","last_name":"Molkenbur","full_name":"Molkenbur, Ronja"},{"full_name":"Lanzerstorfer, Peter","last_name":"Lanzerstorfer","first_name":"Peter"},{"last_name":"Pezzano","full_name":"Pezzano, Fabio","first_name":"Fabio"},{"full_name":"Agazzi, Costanza","last_name":"Agazzi","first_name":"Costanza"},{"last_name":"Hauschild","full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","orcid":"0000-0001-9843-3522"},{"first_name":"Saumey","full_name":"Jain, Saumey","last_name":"Jain"},{"first_name":"Jeroen M.","last_name":"Jacques","full_name":"Jacques, Jeroen M."},{"last_name":"Venturini","full_name":"Venturini, Valeria","first_name":"Valeria"},{"full_name":"Knapp, Christian","last_name":"Knapp","first_name":"Christian"},{"full_name":"Xie, Yufei","last_name":"Xie","first_name":"Yufei"},{"full_name":"Merrin, Jack","last_name":"Merrin","orcid":"0000-0001-5145-4609","first_name":"Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Weghuber, Julian","last_name":"Weghuber","first_name":"Julian"},{"first_name":"Marcel","full_name":"Schaaf, Marcel","last_name":"Schaaf"},{"full_name":"Quidant, Romain","last_name":"Quidant","first_name":"Romain"},{"orcid":"0000-0001-6165-5738","first_name":"Eva","id":"3EB04B78-F248-11E8-B48F-1D18A9856A87","full_name":"Kiermaier, Eva","last_name":"Kiermaier"},{"first_name":"Jaime","last_name":"Ortega Arroyo","full_name":"Ortega Arroyo, Jaime"},{"last_name":"Ruprecht","full_name":"Ruprecht, Verena","first_name":"Verena","id":"4D71A03A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4088-8633"},{"first_name":"Stefan","id":"355AA5A0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2670-2217","last_name":"Wieser","full_name":"Wieser, Stefan"}],"abstract":[{"lang":"eng","text":"Effective immune responses rely on the efficient migration of leukocytes. Yet, how temperature regulates migration dynamics at the single-cell level has remained poorly understood. Using zebrafish embryos and mouse tissue explants, we found that temperature positively regulates leukocyte migration speed, exploration, and arrival frequencies to wounds and lymph vessels. Complementary 2D and 3D cultures revealed that this thermokinetic control of cell migration is conserved across immune cell types, independently of the 3D tissue environment. By applying precise (sub-)cellular temperature modulation, we identified a rapid and reversible thermo-response that depends on myosin II activity. Small physiological increases in temperature (1°C –2°C), as present during fever-like conditions, profoundly increased immune responses by accelerating arrival times at lymphatic vessels and tissue wounds. These findings identify myosin-II-dependent actomyosin contractility as a critical mechanical structure regulating single-cell thermo-adaptability, with physiological implications for tuning the speed of immune responses in vivo."}],"date_updated":"2025-12-29T09:23:58Z","oa_version":"Published Version","doi":"10.1016/j.devcel.2025.10.006","language":[{"iso":"eng"}],"publisher":"Elsevier","date_published":"2025-11-04T00:00:00Z","oa":1,"article_type":"original","external_id":{"pmid":["41192429"]},"year":"2025","quality_controlled":"1","month":"11","scopus_import":"1","pmid":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"20859","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","type":"journal_article","citation":{"apa":"Company-Garrido, I., Zurita Carpio, A., Colomer-Rosell, M., Ciraulo, B., Molkenbur, R., Lanzerstorfer, P., … Wieser, S. (2025). Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. <i>Developmental Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">https://doi.org/10.1016/j.devcel.2025.10.006</a>","ama":"Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, et al. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. <i>Developmental Cell</i>. 2025. doi:<a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">10.1016/j.devcel.2025.10.006</a>","ieee":"I. Company-Garrido <i>et al.</i>, “Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses,” <i>Developmental Cell</i>. Elsevier, 2025.","short":"I. Company-Garrido, A. Zurita Carpio, M. Colomer-Rosell, B. Ciraulo, R. Molkenbur, P. Lanzerstorfer, F. Pezzano, C. Agazzi, R. Hauschild, S. Jain, J.M. Jacques, V. Venturini, C. Knapp, Y. Xie, J. Merrin, J. Weghuber, M. Schaaf, R. Quidant, E. Kiermaier, J. Ortega Arroyo, V. Ruprecht, S. Wieser, Developmental Cell (2025).","chicago":"Company-Garrido, Iván, Alberto Zurita Carpio, Mariona Colomer-Rosell, Bernard Ciraulo, Ronja Molkenbur, Peter Lanzerstorfer, Fabio Pezzano, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” <i>Developmental Cell</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">https://doi.org/10.1016/j.devcel.2025.10.006</a>.","ista":"Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, Ciraulo B, Molkenbur R, Lanzerstorfer P, Pezzano F, Agazzi C, Hauschild R, Jain S, Jacques JM, Venturini V, Knapp C, Xie Y, Merrin J, Weghuber J, Schaaf M, Quidant R, Kiermaier E, Ortega Arroyo J, Ruprecht V, Wieser S. 2025. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Developmental Cell.","mla":"Company-Garrido, Iván, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” <i>Developmental Cell</i>, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">10.1016/j.devcel.2025.10.006</a>."},"publication_status":"epub_ahead"},{"article_type":"original","publisher":"Taylor & Francis","language":[{"iso":"eng"}],"doi":"10.1080/00107514.2025.2586370","date_published":"2025-12-04T00:00:00Z","issue":"1-4","oa":1,"quality_controlled":"1","year":"2025","page":"116-151","external_id":{"arxiv":["2511.04843"]},"_id":"20864","scopus_import":"1","month":"12","arxiv":1,"type":"journal_article","corr_author":"1","volume":66,"publication_status":"published","citation":{"short":"J.J. Matthee, Contemporary Physics 66 (2025) 116–151.","mla":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>, vol. 66, no. 1–4, Taylor &#38; Francis, 2025, pp. 116–51, doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>.","chicago":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>. Taylor &#38; Francis, 2025. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>.","ista":"Matthee JJ. 2025. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. 66(1–4), 116–151.","ama":"Matthee JJ. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. 2025;66(1-4):116-151. doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>","apa":"Matthee, J. J. (2025). JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>","ieee":"J. J. Matthee, “JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies,” <i>Contemporary Physics</i>, vol. 66, no. 1–4. Taylor &#38; Francis, pp. 116–151, 2025."},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"repository","article_processing_charge":"No","acknowledgement":"I thank Claudia Di Cesare, Edoardo Iani, Gauri Kotiwale and Wendy Sun for proofreading, Daichi Kashino, Gauri Kotiwale, Sara Mascia, Benjamín Navarette and Joris Witstok for their assistance in preparing some of the Figures, and Richard Ellis and Stephen Blundell for constructive comments. Funded by the European Union (ERC, AGENTS, 101076224).","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2511.04843"}],"date_created":"2025-12-29T12:05:25Z","status":"public","publication":"Contemporary Physics","publication_identifier":{"issn":["0010-7514"],"eissn":["1366-5812"]},"department":[{"_id":"JoMa"}],"project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"OA_type":"green","day":"04","title":"JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies","abstract":[{"lang":"eng","text":"Studies of the distant Universe are providing key insights into our understanding of the formation of galaxies. The advent of the James Webb Space Telescope (JWST) has significantly enhanced our observational capabilities, leading to an expanded redshift frontier, providing unprecedented detail in the characterisation of early galaxies and enabling the discovery of new populations of accreting black holes. This review aims to provide an introduction to the basic processes and components that shape the observed spectra of galaxies, with a focus on their relevance to techniques with which high-redshift galaxies are selected. The review further introduces specific topics that have attracted significant attention in recent literature, including the discovery of highly efficient galaxy formation in the early Universe, the relation between galaxies and the process of reionization, new insights into the formation of the first stars and the enrichment of interstellar gas with heavy elements, and breakthroughs in our understanding of the origins of supermassive black holes."}],"oa_version":"Preprint","date_updated":"2026-04-07T08:44:00Z","intvolume":"        66","author":[{"orcid":"0000-0003-2871-127X","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","last_name":"Matthee"}]},{"citation":{"short":"E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Acta Informatica 62 (2025).","mla":"Bartocci, Ezio, et al. “Hypernode Automata.” <i>Acta Informatica</i>, vol. 62, no. 4, 43, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>.","ista":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Hypernode automata. Acta Informatica. 62(4), 43.","chicago":"Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” <i>Acta Informatica</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>.","apa":"Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A. (2025). Hypernode automata. <i>Acta Informatica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>","ama":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. <i>Acta Informatica</i>. 2025;62(4). doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>","ieee":"E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” <i>Acta Informatica</i>, vol. 62, no. 4. Springer Nature, 2025."},"publication_status":"published","corr_author":"1","volume":62,"type":"journal_article","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20866","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"arxiv":1,"month":"12","scopus_import":"1","year":"2025","quality_controlled":"1","external_id":{"arxiv":["2305.02836"]},"article_type":"original","oa":1,"file":[{"file_size":7117003,"content_type":"application/pdf","date_updated":"2026-01-05T12:26:43Z","file_name":"2025_ActaInformatica_Bartocci.pdf","access_level":"open_access","checksum":"06ed45a1218ad8464818803ae2968aaf","file_id":"20944","success":1,"creator":"dernst","relation":"main_file","date_created":"2026-01-05T12:26:43Z"}],"issue":"4","date_published":"2025-12-09T00:00:00Z","publisher":"Springer Nature","doi":"10.1007/s00236-025-00509-8","language":[{"iso":"eng"}],"intvolume":"        62","date_updated":"2026-01-05T12:27:41Z","oa_version":"Published Version","article_number":"43","abstract":[{"lang":"eng","text":"In this work, we present hypernode automata as a specification formalism for hyperproperties of systems whose executions may be misaligned among themselves, such as concurrent systems. These automata consist of nodes labeled with hypernode logic formulas and transitions marked with synchronizing actions. Hypernode logic formulas establish relations between sequences of variable values among different system executions. This logic enables both synchronous and asynchronous analysis of traces. In its asynchronous view on execution traces, hypernode formulas establish relations on the order of value changes for each variable without correlating their timing. In both views, the analysis of different execution traces is synchronized through the transitions of hypernode automata. By combining logic’s declarative nature with automata’s procedural power, hypernode automata seamlessly integrate asynchronicity requirements at the node level with synchronicity between node transitions. We show that the model-checking problem for hypernode automata is decidable for specifications where each node specifies either a synchronous or an asynchronous requirement for the system’s executions, but not both."}],"author":[{"last_name":"Bartocci","full_name":"Bartocci, Ezio","first_name":"Ezio"},{"full_name":"Chalupa, Marek","last_name":"Chalupa","first_name":"Marek","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463"},{"full_name":"Henzinger, Thomas A","last_name":"Henzinger","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A"},{"full_name":"Nickovic, Dejan","last_name":"Nickovic","first_name":"Dejan","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Oliveira da Costa","full_name":"Oliveira da Costa, Ana","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","first_name":"Ana","orcid":"0000-0002-8741-5799"}],"OA_type":"hybrid","has_accepted_license":"1","project":[{"name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"},{"grant_number":"F8502","_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","name":"Interface Theory for Security and Privacy"}],"department":[{"_id":"ToHe"}],"title":"Hypernode automata","day":"09","ddc":["000"],"related_material":{"record":[{"status":"public","relation":"earlier_version","id":"14405"}]},"publication":"Acta Informatica","ec_funded":1,"publication_identifier":{"issn":["0001-5903"],"eissn":["1432-0525"]},"article_processing_charge":"Yes (via OA deal)","file_date_updated":"2026-01-05T12:26:43Z","status":"public","date_created":"2025-12-29T12:07:12Z","acknowledgement":"This work was supported in part by the Austrian Science Fund (FWF) SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute of Science and Technology (IST Austria)."},{"ddc":["500"],"day":"20","title":"Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces","department":[{"_id":"HeEd"}],"project":[{"call_identifier":"FWF","grant_number":"I04245","_id":"26AD5D90-B435-11E9-9278-68D0E5697425","name":"Algebraic Footprints of Geometric Features in Homology"}],"OA_type":"diamond","has_accepted_license":"1","author":[{"full_name":"Zava, Nicolò","last_name":"Zava","orcid":"0000-0001-8686-1888","first_name":"Nicolò","id":"c8b3499c-7a77-11eb-b046-aa368cbbf2ad"}],"abstract":[{"lang":"eng","text":"We discuss the embeddability of subspaces of the Gromov–Hausdorff space, which consists of isometry classes of compact metric spaces endowed with the Gromov–Hausdorff distance, into Hilbert spaces. These embeddings are particularly valuable for applications to topological data analysis. We prove that its subspace consisting of metric spaces with at most n points has asymptotic dimension n(n−1)∕2. Thus, there exists a coarse embedding of that space into a Hilbert space. On the contrary, if the number of points is not bounded, then the subspace cannot be coarsely embedded into any uniformly convex Banach space and so, in particular, into any Hilbert space. Furthermore, we prove that, even if we restrict to finite metric spaces whose diameter is bounded by some constant, the subspace still cannot be bi-Lipschitz embedded into any finite-dimensional Hilbert space. We obtain both nonembeddability results by finding obstructions to coarse and bi-Lipschitz embeddings in families of isometry classes of finite subsets of the real line endowed with the Euclidean–Hausdorff distance."}],"oa_version":"Published Version","date_updated":"2026-01-05T12:19:09Z","intvolume":"        25","acknowledgement":"The author was supported by the FWF Grant, Project number I4245-N35. The author would like to thank Thomas Weighill for the helpful discussions around Theorem 3.10, and Takamitsu Yamauchi for bringing to my attention the fundamental reference [35]. Furthermore, the author\r\nis thankful for the detailed and helpful comments of the reviewer of this manuscript.","date_created":"2025-12-29T12:09:09Z","file_date_updated":"2026-01-05T12:16:38Z","status":"public","PlanS_conform":"1","article_processing_charge":"No","publication_identifier":{"eissn":["1472-2739"],"issn":["1472-2747"]},"publication":"Algebraic & Geometric Topology","month":"11","scopus_import":"1","arxiv":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"20867","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","type":"journal_article","corr_author":"1","volume":25,"publication_status":"published","citation":{"ieee":"N. Zava, “Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces,” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8. Mathematical Sciences Publishers, pp. 5153–5174, 2025.","apa":"Zava, N. (2025). Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>","ama":"Zava N. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. 2025;25(8):5153-5174. doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>","mla":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8, Mathematical Sciences Publishers, 2025, pp. 5153–74, doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>.","ista":"Zava N. 2025. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic &#38; Geometric Topology. 25(8), 5153–5174.","chicago":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers, 2025. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>.","short":"N. Zava, Algebraic &#38; Geometric Topology 25 (2025) 5153–5174."},"date_published":"2025-11-20T00:00:00Z","publisher":"Mathematical Sciences Publishers","language":[{"iso":"eng"}],"doi":"10.2140/agt.2025.25.5153","issue":"8","file":[{"checksum":"1e05b4f17a44500ae1ae1e21bc636f6a","access_level":"open_access","file_name":"2025_AlgebraicGeomTopology_Zava.pdf","file_id":"20943","file_size":574389,"date_updated":"2026-01-05T12:16:38Z","content_type":"application/pdf","date_created":"2026-01-05T12:16:38Z","success":1,"relation":"main_file","creator":"dernst"}],"oa":1,"article_type":"original","page":"5153-5174","external_id":{"arxiv":["2303.04730"]},"quality_controlled":"1","year":"2025"},{"article_processing_charge":"No","status":"public","date_created":"2025-12-29T12:11:28Z","acknowledgement":"This research was supported by the National Natural Science Foundation of China (grants 42288101 and 42175066) and Shanghai International Science and Technology Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554), the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.","publication":"Nature Mental Health","publication_identifier":{"issn":["2731-6076"]},"OA_type":"closed access","project":[{"name":"Reducing the impact of major environmental challenges on mental health","grant_number":"101057429","_id":"349d1832-11ca-11ed-8bc3-d79b574010e0"}],"department":[{"_id":"GaNo"}],"title":"Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai","day":"01","date_updated":"2026-01-05T12:02:29Z","intvolume":"         3","oa_version":"None","abstract":[{"text":"Residents of low-latitude megacities face growing vulnerability to humid-heat stress under urbanization and global warming, yet limited research has assessed the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat exposures in these cities. Here we quantify the hospital admissions of MBDs in Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat, and project future burdens under various greenhouse gas (GHG)-emission and population scenarios. Humid heat drives a higher morbidity burden than high temperature alone, especially in humid-heat nights. Without population change, the humid-heat-related morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval 56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465 (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing emissions to the lowest pathway. With projected population decline, the attributable hospital admissions will decrease toward century’s end. These findings highlight the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme humid heat.","lang":"eng"}],"author":[{"first_name":"Chen","full_name":"Liang, Chen","last_name":"Liang"},{"first_name":"Jiacan","full_name":"Yuan, Jiacan","last_name":"Yuan"},{"first_name":"Renhe","last_name":"Zhang","full_name":"Zhang, Renhe"},{"full_name":"Tang, Xu","last_name":"Tang","first_name":"Xu"},{"last_name":"Schumann","full_name":"Schumann, Gunter","first_name":"Gunter"},{"first_name":"Esther","last_name":"Hitchen","full_name":"Hitchen, Esther"},{"full_name":"Polemiti, Elli","last_name":"Polemiti","first_name":"Elli"},{"full_name":"Serin, Emin","last_name":"Serin","first_name":"Emin"},{"full_name":"Kebir, Hedi","last_name":"Kebir","first_name":"Hedi"},{"last_name":"Lett","full_name":"Lett, Tristram A.","first_name":"Tristram A."},{"last_name":"Vaidya","full_name":"Vaidya, Nilakshi","first_name":"Nilakshi"},{"first_name":"Jean-Charles","last_name":"Roy","full_name":"Roy, Jean-Charles"},{"last_name":"Walter","full_name":"Walter, Henrik","first_name":"Henrik"},{"first_name":"Andreas","full_name":"Heinz, Andreas","last_name":"Heinz"},{"full_name":"Ralser, Markus","last_name":"Ralser","first_name":"Markus"},{"first_name":"Sven","full_name":"Twardziok, Sven","last_name":"Twardziok"},{"full_name":"Eils, Roland","last_name":"Eils","first_name":"Roland"},{"first_name":"Marcel","full_name":"Jentsch, Marcel","last_name":"Jentsch"},{"last_name":"Taron","full_name":"Taron, Ulrike-Helene","first_name":"Ulrike-Helene"},{"last_name":"Schütz","full_name":"Schütz, Tatjana","first_name":"Tatjana"},{"first_name":"Kerstin","last_name":"Schepanski","full_name":"Schepanski, Kerstin"},{"first_name":"Tobias","last_name":"Banaschewski","full_name":"Banaschewski, Tobias"},{"first_name":"Maja","last_name":"Neidhart","full_name":"Neidhart, Maja"},{"first_name":"Andreas","last_name":"Meyer-Lindenberg","full_name":"Meyer-Lindenberg, Andreas"},{"full_name":"Tost, Heike","last_name":"Tost","first_name":"Heike"},{"full_name":"Holz, Nathalie","last_name":"Holz","first_name":"Nathalie"},{"first_name":"Emanuel","last_name":"Schwarz","full_name":"Schwarz, Emanuel"},{"last_name":"Stringaris","full_name":"Stringaris, Argyris","first_name":"Argyris"},{"full_name":"Christmann, Nina","last_name":"Christmann","first_name":"Nina"},{"last_name":"Janson","full_name":"Janson, Karina","first_name":"Karina"},{"last_name":"Nees","full_name":"Nees, Frauke","first_name":"Frauke"},{"first_name":"Maja","last_name":"Neidhart","full_name":"Neidhart, Maja"},{"full_name":"Seefried, Beke","last_name":"Seefried","first_name":"Beke"},{"full_name":"Aden, Rieke","last_name":"Aden","first_name":"Rieke"},{"first_name":"Ole A.","last_name":"Andreassen","full_name":"Andreassen, Ole A."},{"last_name":"Westlye","full_name":"Westlye, Lars T.","first_name":"Lars T."},{"last_name":"van der Meer","full_name":"van der Meer, Dennis","first_name":"Dennis"},{"last_name":"Fernández-Cabello","full_name":"Fernández-Cabello, Sara","first_name":"Sara"},{"last_name":"Kjelkenes","full_name":"Kjelkenes, Rikka","first_name":"Rikka"},{"full_name":"Ask, Helga","last_name":"Ask","first_name":"Helga"},{"last_name":"Rapp","full_name":"Rapp, Michael","first_name":"Michael"},{"last_name":"Tschorn","full_name":"Tschorn, Mira","first_name":"Mira"},{"first_name":"Sarah Jane","full_name":"Böttger, Sarah Jane","last_name":"Böttger"},{"last_name":"Marquand","full_name":"Marquand, Andre","first_name":"Andre"},{"full_name":"Bernas, Antoine","last_name":"Bernas","first_name":"Antoine"},{"orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","first_name":"Gaia","full_name":"Novarino, Gaia","last_name":"Novarino"},{"full_name":"Slater, Mel","last_name":"Slater","first_name":"Mel"},{"first_name":"Jaime","full_name":"Gallego, Jaime","last_name":"Gallego"},{"first_name":"Álvaro","full_name":"Pastor, Álvaro","last_name":"Pastor"},{"first_name":"Guillem","last_name":"Feixas","full_name":"Feixas, Guillem"},{"first_name":"Francisco José","last_name":"Eiroa-Orosa","full_name":"Eiroa-Orosa, Francisco José"},{"full_name":"Nöthen, Markus M.","last_name":"Nöthen","first_name":"Markus M."},{"first_name":"Andreas J.","full_name":"Forstner, Andreas J.","last_name":"Forstner"},{"first_name":"Isabelle","full_name":"Claus, Isabelle","last_name":"Claus"},{"first_name":"Carina","full_name":"Mathey, Carina","last_name":"Mathey"},{"first_name":"Stefanie","full_name":"Heilmann-Heimbach, Stefanie","last_name":"Heilmann-Heimbach"},{"full_name":"Hoffmann, Per","last_name":"Hoffmann","first_name":"Per"},{"first_name":"Abigail","full_name":"Miller, Abigail","last_name":"Miller"},{"first_name":"Peter","last_name":"Sommer","full_name":"Sommer, Peter"},{"full_name":"Schmitt, Karen","last_name":"Schmitt","first_name":"Karen"},{"first_name":"Johannes","last_name":"Wilbertz","full_name":"Wilbertz, Johannes"},{"first_name":"Myrto","last_name":"Patraskaki","full_name":"Patraskaki, Myrto"},{"first_name":"Viktor","full_name":"Jirsa, Viktor","last_name":"Jirsa"},{"first_name":"Spase","full_name":"Petkoski, Spase","last_name":"Petkoski"},{"first_name":"Anastasios-Polykarpos","last_name":"Athanasiadis","full_name":"Athanasiadis, Anastasios-Polykarpos"},{"last_name":"Spanlang","full_name":"Spanlang, Bernhard","first_name":"Bernhard"},{"first_name":"Charlie","full_name":"Pearmund, Charlie","last_name":"Pearmund"},{"first_name":"Sören","full_name":"Hese, Sören","last_name":"Hese"},{"first_name":"Paul","full_name":"Renner, Paul","last_name":"Renner"},{"first_name":"Tianye","full_name":"Jia, Tianye","last_name":"Jia"},{"full_name":"Chang, Xiao","last_name":"Chang","first_name":"Xiao"},{"full_name":"Dai, Yuxiang","last_name":"Dai","first_name":"Yuxiang"},{"first_name":"Yunman","last_name":"Xia","full_name":"Xia, Yunman"},{"first_name":"Yuzhu","last_name":"Li","full_name":"Li, Yuzhu"},{"first_name":"Yanqing","full_name":"Zhang, Yanqing","last_name":"Zhang"},{"full_name":"Calhoun, Vince","last_name":"Calhoun","first_name":"Vince"},{"last_name":"Thompson","full_name":"Thompson, Paul","first_name":"Paul"},{"full_name":"Clinton, Nicholas","last_name":"Clinton","first_name":"Nicholas"},{"first_name":"Sylvane","last_name":"Desrivières","full_name":"Desrivières, Sylvane"},{"first_name":"Kofoworola","full_name":"Agunbiade, Kofoworola","last_name":"Agunbiade"},{"first_name":"Xinyang","full_name":"Yu, Xinyang","last_name":"Yu"},{"first_name":"Zuo","full_name":"Zhang, Zuo","last_name":"Zhang"},{"first_name":"Di","full_name":"Chen, Di","last_name":"Chen"},{"first_name":"Allan H.","full_name":"Young, Allan H.","last_name":"Young"},{"first_name":"Ameli","full_name":"Schwalber, Ameli","last_name":"Schwalber"},{"first_name":"Vanessa","last_name":"Köhler","full_name":"Köhler, Vanessa"},{"last_name":"Stahl","full_name":"Stahl, Bernd","first_name":"Bernd"},{"first_name":"George","last_name":"Ogoh","full_name":"Ogoh, George"},{"full_name":"Schikowski, Tamara","last_name":"Schikowski","first_name":"Tamara"},{"first_name":"Ragnhild","last_name":"Brandlistuen","full_name":"Brandlistuen, Ragnhild"}],"article_type":"original","issue":"12","language":[{"iso":"eng"}],"doi":"10.1038/s44220-025-00519-y","date_published":"2025-12-01T00:00:00Z","publisher":"Springer Nature","year":"2025","quality_controlled":"1","page":"1532-1544","_id":"20868","month":"12","scopus_import":"1","citation":{"short":"C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti, E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser, S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski, M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen, L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater, J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner, I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer, K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis, B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia, Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade, X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh, T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544.","mla":"Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>.","chicago":"Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>.","ista":"Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N, Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G, Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S, Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V, Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T, Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 3(12), 1532–1544.","ieee":"C. Liang <i>et al.</i>, “Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai,” <i>Nature Mental Health</i>, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025.","apa":"Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen, R. (2025). Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>","ama":"Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. 2025;3(12):1532-1544. doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>"},"publication_status":"published","volume":3,"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"article_processing_charge":"No","status":"public","date_created":"2025-12-29T12:14:26Z","acknowledgement":"Thank you to Doug Schemske and Nick Barton forcritically reviewing the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for their thoughtfulcomments and suggestions, which substantially improved the clarity and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon 2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement No. 754411","publication":"American Journal of Botany","related_material":{"link":[{"relation":"software","url":"https://github.com/Alex-Fuster/hybrids_drought"}]},"ec_funded":1,"publication_identifier":{"issn":["0002-9122"],"eissn":["1537-2197"]},"OA_type":"closed access","project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"department":[{"_id":"NiBa"}],"title":"Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors","day":"01","intvolume":"       112","date_updated":"2026-01-05T11:56:22Z","article_number":"e70129","oa_version":"None","abstract":[{"lang":"eng","text":"Premise: What maintains trait divergence in the face of gene flow? Two varieties of wild snapdragon (Antirrhinum majus) characterized by divergent flower color hybridize in their native range. Selection on flower color genes is indicated by sharp clines, but the selective agents have not been demonstrated. Although previous work has focused on pollinators, pigmentation genes can also contribute to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates stress tolerance, which could contribute to hybrid zone maintenance through parental niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus, yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods: We experimentally compared drought tolerance of each morphotype from allopatric crosses within and between varieties using three greenhouse treatments. Control plants were watered as needed, while drought-treated plants were watered half as often, either from the transplant stage (“early” drought), or from flowering onset (“late” drought).\r\nResults: Parental morphotypes responded identically to drought in fitness and most phenotypic traits. However, hybrids had lower survival (14%) under late drought stress than parental morphotypes (70%). All hybrids that flowered in the late drought treatment died, compared to ~20% of flowering parental morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially contribute to flower color divergence in the face of gene flow in A. majus. Further research should test the relevance of our results to field conditions and explicitly probe the role of flower color genes in drought tolerance."}],"author":[{"last_name":"Fuster‐Calvo","full_name":"Fuster‐Calvo, Alexandre","first_name":"Alexandre"},{"full_name":"Jaworski, Coline C.","last_name":"Jaworski","first_name":"Coline C."},{"orcid":"0000-0002-8511-0254","first_name":"Thomas","id":"3153D6D4-F248-11E8-B48F-1D18A9856A87","full_name":"Ellis, Thomas","last_name":"Ellis"},{"id":"3B4A7CE2-F248-11E8-B48F-1D18A9856A87","first_name":"Carina","orcid":"0000-0002-7354-8574","last_name":"Baskett","full_name":"Baskett, Carina"}],"article_type":"original","issue":"12","date_published":"2025-12-01T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1002/ajb2.70129","publisher":"Wiley","year":"2025","quality_controlled":"1","external_id":{"pmid":["41327576 "]},"_id":"20869","month":"12","scopus_import":"1","pmid":1,"citation":{"short":"A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of Botany 112 (2025).","mla":"Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>, vol. 112, no. 12, e70129, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>.","ista":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. American Journal of Botany. 112(12), e70129.","chicago":"Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>.","apa":"Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., &#38; Baskett, C. (2025). Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. Wiley. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>","ama":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. 2025;112(12). doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>","ieee":"A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors,” <i>American Journal of Botany</i>, vol. 112, no. 12. Wiley, 2025."},"publication_status":"published","volume":112,"type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"}]