[{"_id":"19879","publication_identifier":{"issn":["0195-6698"]},"isi":1,"OA_place":"publisher","date_updated":"2025-09-30T13:42:59Z","title":"Precoloring extension in planar near-Eulerian-triangulations","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"MaKw"}],"article_type":"original","month":"06","OA_type":"hybrid","oa_version":"Published Version","type":"journal_article","publication_status":"published","publisher":"Elsevier","arxiv":1,"doi":"10.1016/j.ejc.2025.104138","intvolume":"       127","corr_author":"1","day":"01","scopus_import":"1","quality_controlled":"1","date_created":"2025-06-23T13:54:46Z","citation":{"short":"Z. Dvořák, B. Moore, M. Seifrtová, R. Šámal, European Journal of Combinatorics 127 (2025).","ieee":"Z. Dvořák, B. Moore, M. Seifrtová, and R. Šámal, “Precoloring extension in planar near-Eulerian-triangulations,” <i>European Journal of Combinatorics</i>, vol. 127. Elsevier, 2025.","ama":"Dvořák Z, Moore B, Seifrtová M, Šámal R. Precoloring extension in planar near-Eulerian-triangulations. <i>European Journal of Combinatorics</i>. 2025;127. doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104138\">10.1016/j.ejc.2025.104138</a>","ista":"Dvořák Z, Moore B, Seifrtová M, Šámal R. 2025. Precoloring extension in planar near-Eulerian-triangulations. European Journal of Combinatorics. 127, 104138.","mla":"Dvořák, Zdeněk, et al. “Precoloring Extension in Planar Near-Eulerian-Triangulations.” <i>European Journal of Combinatorics</i>, vol. 127, 104138, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104138\">10.1016/j.ejc.2025.104138</a>.","chicago":"Dvořák, Zdeněk, Benjamin Moore, Michaela Seifrtová, and Robert Šámal. “Precoloring Extension in Planar Near-Eulerian-Triangulations.” <i>European Journal of Combinatorics</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.ejc.2025.104138\">https://doi.org/10.1016/j.ejc.2025.104138</a>.","apa":"Dvořák, Z., Moore, B., Seifrtová, M., &#38; Šámal, R. (2025). Precoloring extension in planar near-Eulerian-triangulations. <i>European Journal of Combinatorics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ejc.2025.104138\">https://doi.org/10.1016/j.ejc.2025.104138</a>"},"has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","article_number":"104138","file_date_updated":"2025-06-24T06:33:30Z","oa":1,"license":"https://creativecommons.org/licenses/by/4.0/","ddc":["510"],"abstract":[{"lang":"eng","text":"We consider the 4-precoloring extension problem in planar near-Eulerian- triangulations, i.e., plane graphs where all faces except possibly for the outer one have length three, all vertices not incident with the outer face have even degree, and exactly the vertices incident with the outer face are precolored. We give a necessary topological condition for the precoloring to extend, and give a complete characterization when the outer face has length at most five and when all vertices of the outer face have odd degree and are colored using only three colors."}],"author":[{"first_name":"Zdeněk","full_name":"Dvořák, Zdeněk","last_name":"Dvořák"},{"first_name":"Benjamin","last_name":"Moore","id":"6dc1a1be-bf1c-11ed-8d2b-d044840f49d6","full_name":"Moore, Benjamin"},{"last_name":"Seifrtová","full_name":"Seifrtová, Michaela","first_name":"Michaela"},{"last_name":"Šámal","full_name":"Šámal, Robert","first_name":"Robert"}],"external_id":{"arxiv":["2312.13061"],"isi":["001443061400001"]},"volume":127,"file":[{"file_size":564203,"success":1,"file_name":"2025_EuropJournCombinatorics_Dvorak.pdf","access_level":"open_access","content_type":"application/pdf","date_created":"2025-06-24T06:33:30Z","checksum":"8b3585df45b25091fba9bee9854b7d01","date_updated":"2025-06-24T06:33:30Z","relation":"main_file","creator":"dernst","file_id":"19887"}],"date_published":"2025-06-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"Supported by project 22-17398S (Flows and cycles in graphs on surfaces) of Czech Science Foundation. An extended abstract appeared in Proceedings of the 12th European Conference on Combinatorics, Graph Theory and Applications (EUROCOMB’23)","status":"public","year":"2025","publication":"European Journal of Combinatorics","language":[{"iso":"eng"}]},{"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"Quantum transport in the presence of a chiral molecular potential","department":[{"_id":"MiLe"}],"date_updated":"2025-09-30T13:40:55Z","publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"isi":1,"OA_place":"publisher","pmid":1,"ec_funded":1,"_id":"19880","arxiv":1,"oa_version":"Published Version","type":"journal_article","publisher":"AIP Publishing","publication_status":"published","OA_type":"hybrid","article_type":"original","project":[{"_id":"2688CF98-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"801770","name":"Angulon: physics and applications of a new quasiparticle"},{"grant_number":"101062862","name":"Non-Equilibrium Field Theory of Molecular Rotations","_id":"bd7b5202-d553-11ed-ba76-9b1c1b258338"},{"name":"Polarons in Lead Halide Perovskites","grant_number":"12078","_id":"8fa7db46-16d5-11f0-9cad-917600954daf"}],"month":"06","file_date_updated":"2025-06-23T14:03:30Z","oa":1,"abstract":[{"lang":"eng","text":"We investigate quantum transport in a two-dimensional electron system coupled to a chiral molecular potential, demonstrating how molecular chirality and orientation affect charge and spin transport properties. We propose a minimal model for realizing true chiral symmetry breaking on a magnetized surface, with a crucial role played by the tilt angle of the molecular dipole with respect to the surface. For non-zero tilting, we show that the Hall response exhibits clear signatures of chirality-induced effects, in both charge- and spin-resolved observables. Concerning the former, tilted enantiomers produce asymmetric Hall conductances and, even more remarkably, the persistence of this feature in the absence of spin–orbit coupling (SOC) signals how the enantiospecific charge response results from electron scattering off the molecular potential. Concerning spin-resolved observables where SOC plays a relevant role, we reveal that chiral symmetry breaking is crucial in enabling spin-flipping processes."}],"ddc":["530"],"has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","article_number":"234106","corr_author":"1","day":"21","scopus_import":"1","citation":{"ista":"Al Hyder R, Lemeshko M, Cappellaro A. 2025. Quantum transport in the presence of a chiral molecular potential. The Journal of Chemical Physics. 162(23), 234106.","apa":"Al Hyder, R., Lemeshko, M., &#38; Cappellaro, A. (2025). Quantum transport in the presence of a chiral molecular potential. <i>The Journal of Chemical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0271155\">https://doi.org/10.1063/5.0271155</a>","mla":"Al Hyder, Ragheed, et al. “Quantum Transport in the Presence of a Chiral Molecular Potential.” <i>The Journal of Chemical Physics</i>, vol. 162, no. 23, 234106, AIP Publishing, 2025, doi:<a href=\"https://doi.org/10.1063/5.0271155\">10.1063/5.0271155</a>.","chicago":"Al Hyder, Ragheed, Mikhail Lemeshko, and Alberto Cappellaro. “Quantum Transport in the Presence of a Chiral Molecular Potential.” <i>The Journal of Chemical Physics</i>. AIP Publishing, 2025. <a href=\"https://doi.org/10.1063/5.0271155\">https://doi.org/10.1063/5.0271155</a>.","short":"R. Al Hyder, M. Lemeshko, A. Cappellaro, The Journal of Chemical Physics 162 (2025).","ieee":"R. Al Hyder, M. Lemeshko, and A. Cappellaro, “Quantum transport in the presence of a chiral molecular potential,” <i>The Journal of Chemical Physics</i>, vol. 162, no. 23. AIP Publishing, 2025.","ama":"Al Hyder R, Lemeshko M, Cappellaro A. Quantum transport in the presence of a chiral molecular potential. <i>The Journal of Chemical Physics</i>. 2025;162(23). doi:<a href=\"https://doi.org/10.1063/5.0271155\">10.1063/5.0271155</a>"},"quality_controlled":"1","date_created":"2025-06-23T13:55:28Z","doi":"10.1063/5.0271155","intvolume":"       162","issue":"23","language":[{"iso":"eng"}],"publication":"The Journal of Chemical Physics","year":"2025","acknowledgement":"We thank Artem Volosniev, Narcis Avarvari, Georgios Koutentakis, Sandro Wimberger, and Binghai Yan for useful discussions. R.A. received funding from the Austrian Academy of Science ÖWA, Grant No. PR1029OEAW03. M.L. acknowledges support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). A.C. received funding from the European Union’s Horizon Europe research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 101062862-NeqMolRot.","status":"public","author":[{"first_name":"Ragheed","full_name":"Al Hyder, Ragheed","id":"d1c405be-ae15-11ed-8510-ccf53278162e","last_name":"Al Hyder"},{"last_name":"Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","first_name":"Mikhail"},{"first_name":"Alberto","last_name":"Cappellaro","id":"9d13b3cb-30a2-11eb-80dc-f772505e8660","orcid":"0000-0001-6110-2359","full_name":"Cappellaro, Alberto"}],"external_id":{"pmid":["40526561"],"arxiv":["2503.14124"],"isi":["001512872900010"]},"volume":162,"date_published":"2025-06-21T00:00:00Z","file":[{"date_updated":"2025-06-23T14:03:30Z","relation":"main_file","file_id":"19881","creator":"dernst","file_size":7202681,"file_name":"2025_JourChemicalPhysics_AlHyder.pdf","success":1,"date_created":"2025-06-23T14:03:30Z","access_level":"open_access","content_type":"application/pdf","checksum":"e278631d949657baa9d5309dad5f4b77"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"day":"01","corr_author":"1","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"date_created":"2025-06-24T06:56:03Z","citation":{"apa":"Saez Mollejo, J. (2025). Automated All-RF Tuning for Spin Qubit Readout and Control. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:19885\">https://doi.org/10.15479/AT:ISTA:19885</a>","chicago":"Saez Mollejo, Jaime. “Automated All-RF Tuning for Spin Qubit Readout and Control.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT:ISTA:19885\">https://doi.org/10.15479/AT:ISTA:19885</a>.","mla":"Saez Mollejo, Jaime. <i>Automated All-RF Tuning for Spin Qubit Readout and Control</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19885\">10.15479/AT:ISTA:19885</a>.","ista":"Saez Mollejo J. 2025. Automated All-RF Tuning for Spin Qubit Readout and Control, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:19885\">10.15479/AT:ISTA:19885</a>.","ama":"Saez Mollejo J. Automated All-RF Tuning for Spin Qubit Readout and Control. 2025. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19885\">10.15479/AT:ISTA:19885</a>","short":"J. Saez Mollejo, (2025).","ieee":"J. Saez Mollejo, “Automated All-RF Tuning for Spin Qubit Readout and Control.” Institute of Science and Technology Austria, 2025."},"doi":"10.15479/AT:ISTA:19885","_id":"19885","file_date_updated":"2025-06-25T07:11:52Z","oa":1,"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"ddc":["530"],"abstract":[{"text":"This .zip file contains the data to reproduce the figures and supplementary figures of \"Automated All-RF Tuning for Spin Qubit Readout and Control\" by Cornelius Carlsson and Jaime Saez-Mollejo et al.","lang":"eng"}],"title":"Automated All-RF Tuning for Spin Qubit Readout and Control","department":[{"_id":"GradSch"},{"_id":"GeKa"}],"has_accepted_license":"1","article_processing_charge":"No","date_updated":"2025-07-01T07:19:26Z","acknowledgement":"The authors would like to thank Barnaby van Straaten, Jonas Schuff, Daniel Jirovec and Hanifa Tidjani for fruitful discussions. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication Facility. G.K. acknowledges support from the NOMIS Foundation, the HORIZON-RIA (project no. 101069515) and the FWF Projects (DOIs: 10.55776/F86 and 10.55776/I5060). N.A. acknowledges support from the European Research Council (grant agreement 948932), and the Royal Society (grant no. URF/R1/191150). This project received support from the US Army Research Office (ARO) under Award No. W911NF-24-2-0043. C.C. acknowledges support from the UKRI Doctoral Training Partnership related to EP/W524311/1 (project ref. 2887634).","status":"public","author":[{"full_name":"Saez Mollejo, Jaime","last_name":"Saez Mollejo","id":"e0390f72-f6e0-11ea-865d-862393336714","first_name":"Jaime"}],"project":[{"_id":"34c0acea-11ca-11ed-8bc3-8775e10fd452","grant_number":"101069515","name":"Integrated Germanium Quantum Technology"},{"_id":"c0977eea-5a5b-11eb-8a69-a862db0cf4d1","grant_number":"I05060","name":"High impedance circuit quantum electrodynamics with hole spins"},{"_id":"34a66131-11ca-11ed-8bc3-a31681c6b03e","name":"Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional  and unconventional topological superconductors","grant_number":"F8606"}],"month":"06","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-06-01T00:00:00Z","file":[{"relation":"main_file","creator":"jsaezmol","file_id":"19893","date_updated":"2025-06-24T15:14:13Z","access_level":"open_access","content_type":"application/x-zip-compressed","date_created":"2025-06-24T15:14:13Z","checksum":"eff1ae9e46599fdfab8da00a2ca3c289","file_size":3404814792,"success":1,"file_name":"DatasetsPaper.zip"},{"relation":"main_file","creator":"jsaezmol","file_id":"19899","date_updated":"2025-06-25T07:11:52Z","access_level":"open_access","content_type":"text/plain","date_created":"2025-06-25T07:11:52Z","checksum":"21840ceac04d677a799b8e5bd919804f","file_size":622,"file_name":"README.txt","success":1}],"contributor":[{"last_name":"Carlsson","contributor_type":"researcher","first_name":"Cornelius"},{"contributor_type":"researcher","last_name":"Fedele","first_name":"Federico "},{"last_name":"Calcaterra","contributor_type":"researcher","first_name":"Stefano"},{"first_name":" Daniel ","last_name":"Chrastina","contributor_type":"researcher"},{"first_name":"Giovanni ","contributor_type":"researcher","last_name":"Isella"},{"contributor_type":"researcher","orcid":"0000-0001-8342-202X","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","last_name":"Katsaros","first_name":"Georgios"},{"contributor_type":"researcher","last_name":"Ares","first_name":"Natalia"}],"year":"2025","oa_version":"Published Version","publisher":"Institute of Science and Technology Austria","type":"research_data"},{"_id":"19928","pmid":1,"OA_place":"publisher","isi":1,"publication_identifier":{"eissn":["1540-9538"],"issn":["0022-1007"]},"date_updated":"2025-12-30T09:00:42Z","title":"Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"MiSi"}],"month":"09","article_type":"original","OA_type":"hybrid","publisher":"Rockefeller University Press","type":"journal_article","publication_status":"published","oa_version":"Published Version","intvolume":"       222","doi":"10.1084/jem.20240109","quality_controlled":"1","citation":{"ieee":"R. Gawish <i>et al.</i>, “Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis,” <i>Journal of Experimental Medicine</i>, vol. 222, no. 9. Rockefeller University Press, 2025.","short":"R. Gawish, R. Varada, F. Deckert, A. Hladik, L. Steinbichl, L. Cimatti, K. Milanovic, M. Jain, N. Torgasheva, A. Tanzer, K. De Paepe, T. Van De Wiele, B. Hausmann, M. Lang, M. Pechhacker, N. Ibrahim, I. de Vries, C. Brostjan, M.K. Sixt, C. Gasche, L. Boon, D. Berry, M.F. Jantsch, F.C. Pereira, C. Vesely, Journal of Experimental Medicine 222 (2025).","ama":"Gawish R, Varada R, Deckert F, et al. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. <i>Journal of Experimental Medicine</i>. 2025;222(9). doi:<a href=\"https://doi.org/10.1084/jem.20240109\">10.1084/jem.20240109</a>","apa":"Gawish, R., Varada, R., Deckert, F., Hladik, A., Steinbichl, L., Cimatti, L., … Vesely, C. (2025). Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. <i>Journal of Experimental Medicine</i>. Rockefeller University Press. <a href=\"https://doi.org/10.1084/jem.20240109\">https://doi.org/10.1084/jem.20240109</a>","mla":"Gawish, Riem, et al. “Filamin A Editing in Myeloid Cells Reduces Intestinal Inflammation and Protects from Colitis.” <i>Journal of Experimental Medicine</i>, vol. 222, no. 9, e20240109, Rockefeller University Press, 2025, doi:<a href=\"https://doi.org/10.1084/jem.20240109\">10.1084/jem.20240109</a>.","chicago":"Gawish, Riem, Rajagopal Varada, Florian Deckert, Anastasiya Hladik, Linda Steinbichl, Laura Cimatti, Katarina Milanovic, et al. “Filamin A Editing in Myeloid Cells Reduces Intestinal Inflammation and Protects from Colitis.” <i>Journal of Experimental Medicine</i>. Rockefeller University Press, 2025. <a href=\"https://doi.org/10.1084/jem.20240109\">https://doi.org/10.1084/jem.20240109</a>.","ista":"Gawish R, Varada R, Deckert F, Hladik A, Steinbichl L, Cimatti L, Milanovic K, Jain M, Torgasheva N, Tanzer A, De Paepe K, Van De Wiele T, Hausmann B, Lang M, Pechhacker M, Ibrahim N, de Vries I, Brostjan C, Sixt MK, Gasche C, Boon L, Berry D, Jantsch MF, Pereira FC, Vesely C. 2025. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. 222(9), e20240109."},"date_created":"2025-06-29T22:01:15Z","scopus_import":"1","day":"01","article_number":"e20240109","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","abstract":[{"text":"Patho-mechanistic origins of ulcerative colitis are still poorly understood. The actin cross-linker filamin A (FLNA) impacts cellular responses through interaction with cytosolic proteins. Posttranscriptional A-to-I editing generates two forms of FLNA: genome-encoded FLNAQ and FLNAR. FLNA is edited in colon fibroblasts, smooth muscle cells, and endothelial cells. We found that the FLNA editing status determines colitis severity. Editing was highest in healthy colons and reduced during murine and human colitis. Mice that exclusively express FLNAR were highly resistant to DSS-induced colitis, whereas fully FLNAQ animals developed severe inflammation. While the genetic induction of FLNA editing influenced transcriptional states of structural cells and microbiome composition, we found that FLNAR exerts protection specifically via myeloid cells, which are physiologically unedited. Introducing fixed FLNAR did not hamper cell migration but reduced macrophage inflammation and rendered neutrophils less prone to NETosis. Thus, loss of FLNA editing correlates with colitis severity, and targeted editing of myeloid cells serves as a novel therapeutic approach in intestinal inflammation.","lang":"eng"}],"ddc":["570"],"oa":1,"file_date_updated":"2025-12-30T09:00:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-09-01T00:00:00Z","file":[{"creator":"dernst","file_id":"20899","relation":"main_file","date_updated":"2025-12-30T09:00:04Z","checksum":"708d61fb8cf1d83ee1e33ddcfde0857e","content_type":"application/pdf","access_level":"open_access","date_created":"2025-12-30T09:00:04Z","success":1,"file_name":"2025_JEM_Gawish.pdf","file_size":9349311}],"volume":222,"author":[{"full_name":"Gawish, Riem","last_name":"Gawish","first_name":"Riem"},{"full_name":"Varada, Rajagopal","last_name":"Varada","first_name":"Rajagopal"},{"first_name":"Florian","full_name":"Deckert, Florian","last_name":"Deckert"},{"first_name":"Anastasiya","last_name":"Hladik","full_name":"Hladik, Anastasiya"},{"full_name":"Steinbichl, Linda","last_name":"Steinbichl","first_name":"Linda"},{"first_name":"Laura","last_name":"Cimatti","full_name":"Cimatti, Laura"},{"first_name":"Katarina","last_name":"Milanovic","full_name":"Milanovic, Katarina"},{"full_name":"Jain, Mamta","last_name":"Jain","first_name":"Mamta"},{"first_name":"Natalya","full_name":"Torgasheva, Natalya","last_name":"Torgasheva"},{"last_name":"Tanzer","full_name":"Tanzer, Andrea","first_name":"Andrea"},{"full_name":"De Paepe, Kim","last_name":"De Paepe","first_name":"Kim"},{"full_name":"Van De Wiele, Tom","last_name":"Van De Wiele","first_name":"Tom"},{"first_name":"Bela","last_name":"Hausmann","full_name":"Hausmann, Bela"},{"first_name":"Michaela","last_name":"Lang","full_name":"Lang, Michaela"},{"first_name":"Martin","full_name":"Pechhacker, Martin","last_name":"Pechhacker"},{"last_name":"Ibrahim","full_name":"Ibrahim, Nahla","first_name":"Nahla"},{"first_name":"Ingrid","full_name":"De Vries, Ingrid","id":"4C7D837E-F248-11E8-B48F-1D18A9856A87","last_name":"De Vries"},{"full_name":"Brostjan, Christine","last_name":"Brostjan","first_name":"Christine"},{"first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179"},{"first_name":"Christoph","full_name":"Gasche, Christoph","last_name":"Gasche"},{"full_name":"Boon, Louis","last_name":"Boon","first_name":"Louis"},{"first_name":"David","full_name":"Berry, David","last_name":"Berry"},{"full_name":"Jantsch, Michael F.","last_name":"Jantsch","first_name":"Michael F."},{"first_name":"Fatima C.","full_name":"Pereira, Fatima C.","last_name":"Pereira"},{"last_name":"Vesely","full_name":"Vesely, Cornelia","first_name":"Cornelia"}],"external_id":{"isi":["001502896900001"],"pmid":["40471139"]},"acknowledgement":"Sequencing was performed by the Vienna BioCenter Core Facilities (Medical University of Vienna Core Facility) and the Biomedical Sequencing Facility at CeMM, Vienna. Cell sorting and flow cytometry were performed at the Core Facility Flow Cytometry and Imaging (Medical University of Vienna). We thank Jasmin Schwarz, Gudrun Kohl, Petra Pjevac, and Joana Seneca Silva from the Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna for assisting with amplicon and metagenomic sequencing, as well as repositing of sequencing data. We thank Sophia Derdak and Michael Schuster for initial data analysis, Robert Vilvoi and Stephan Hemm for animal handling, Marcel Kertesz for mouse genotyping, and Salwan Roumaia for next generation sequencing sample preparation. Treatment schemes and graphical abstracts were created with https://BioRender.com.\r\n\r\nThis work was supported by the Austrian Science Fund, grant number ZK 57-B28 to C. Vesely, R. Gawish, and F.C. Pereira; grant number V 1025-B to R. Gawish; grant number DOC32-B28 to R. Varada and M.F. Jantsch; and F8007 and P32678 to M.F. Jantsch. Open Access funding provided by Medical University of Vienna.","status":"public","year":"2025","language":[{"iso":"eng"}],"publication":"Journal of Experimental Medicine","issue":"9"},{"title":"zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"JoMa"}],"date_updated":"2026-02-16T12:11:56Z","isi":1,"OA_place":"publisher","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"_id":"19929","arxiv":1,"publication_status":"published","publisher":"EDP Sciences","type":"journal_article","oa_version":"Published Version","OA_type":"diamond","month":"06","article_type":"original","abstract":[{"lang":"eng","text":"Context. The observed Lyman-alpha (Lyα) line profile is a convolution of the complex Lyα radiative transfer taking place in the interstellar, circumgalactic, and intergalactic media (ISM, CGM, and IGM, respectively). Discerning the different components of the Lyα line is crucial in order to use it as a probe of galaxy formation or the evolution of the IGM.\r\n\r\nAims. We aim to present the second version of zELDA (redshift Estimator for Line profiles of Distant Lyman-Alpha emitters), an open-source Python module focused on modelling and fitting observed Lyα line profiles. This new version of zELDA focuses on disentangling the galactic from the IGM effects.\r\n\r\nMethods. We built realistic Lyα line profiles that include the ISM and IGM contributions by combining the Monte Carlo radiative-transfer simulations for the so-called shell model (ISM) and IGM transmission curves generated from TNG100. We used these mock line profiles to train different artificial neural networks. These use the observed spectrum as input and the outflow parameters of the best fitting ‘shell model’ as output along with the redshift and Lyα emission IGM escape fraction of the source.\r\n\r\nResults. We measured the accuracy of zELDA on mock Lyα line profiles. We find that zELDA is capable of reconstructing the ISM emerging Lyα line profile with high levels of accuracy (Kolmogórov-Smirnov<0.1) for 95% of the cases for HST/COS-like observations and 80% for MUSE-WIDE-like observations. zELDA is able to measure the IGM transmission with typical uncertainties below 10% for HST/COS and MUSE-WIDE data.\r\n\r\nConclusions. This work represents a step forward in the high-precision reconstruction of IGM-attenuated Lyα line profiles. zELDA allows the disentanglement of the galactic and IGM contribution shaping the Lyα line shape and thus allows us to use Lyα as a tool to study galaxy and ISM evolution."}],"ddc":["520"],"file_date_updated":"2025-06-30T08:28:40Z","oa":1,"article_processing_charge":"No","article_number":"A139","has_accepted_license":"1","scopus_import":"1","citation":{"ama":"Gurung-López S, Byrohl C, Gronke M, et al. zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. <i>Astronomy &#38; Astrophysics</i>. 2025;698. doi:<a href=\"https://doi.org/10.1051/0004-6361/202453547\">10.1051/0004-6361/202453547</a>","ieee":"S. Gurung-López <i>et al.</i>, “zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks,” <i>Astronomy &#38; Astrophysics</i>, vol. 698. EDP Sciences, 2025.","short":"S. Gurung-López, C. Byrohl, M. Gronke, D. Spinoso, A. Torralba Torregrosa, A. Fernández-Soto, P. Arnalte-Mur, V.J. Martínez, Astronomy &#38; Astrophysics 698 (2025).","ista":"Gurung-López S, Byrohl C, Gronke M, Spinoso D, Torralba Torregrosa A, Fernández-Soto A, Arnalte-Mur P, Martínez VJ. 2025. zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. Astronomy &#38; Astrophysics. 698, A139.","apa":"Gurung-López, S., Byrohl, C., Gronke, M., Spinoso, D., Torralba Torregrosa, A., Fernández-Soto, A., … Martínez, V. J. (2025). zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202453547\">https://doi.org/10.1051/0004-6361/202453547</a>","chicago":"Gurung-López, Siddhartha, Chris Byrohl, Max Gronke, Daniele Spinoso, Alberto Torralba Torregrosa, Alberto Fernández-Soto, Pablo Arnalte-Mur, and Vicent J. Martínez. “ZELDA II: Reconstruction of Galactic Lyman-Alpha Spectra Attenuated by the Intergalactic Medium Using Neural Networks.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202453547\">https://doi.org/10.1051/0004-6361/202453547</a>.","mla":"Gurung-López, Siddhartha, et al. “ZELDA II: Reconstruction of Galactic Lyman-Alpha Spectra Attenuated by the Intergalactic Medium Using Neural Networks.” <i>Astronomy &#38; Astrophysics</i>, vol. 698, A139, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202453547\">10.1051/0004-6361/202453547</a>."},"quality_controlled":"1","date_created":"2025-06-29T22:01:15Z","day":"01","intvolume":"       698","doi":"10.1051/0004-6361/202453547","publication":"Astronomy & Astrophysics","language":[{"iso":"eng"}],"year":"2025","status":"public","acknowledgement":"The authors acknowledge the financial support from the MICIU with funding from the European Union NextGenerationEU and Generalitat Valenciana in the call Programa de Planes Complementarios de I+D+i (PRTR 2022) Project (VAL-JPAS), reference ASFAE/2022/025. This work is part of the research Project PID2023-149420NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU. This work is also supported by the project of excellence PROMETEO CIPROM/2023/21 of the Conselleria de Educación, Universidades y Empleo (Generalitat Valenciana). MG thanks the Max Planck Society for support through the Max Planck Research Group. DS acknowledges the support by the Tsinghua Shui Mu Scholarship, funding of the National Key R&D Program of China (grant no. 2023YFA1605600), the science research grants from the China Manned Space Project with no. CMS-CSST2021-A05, and the Tsinghua University Initiative Scientific Research Program (no. 20223080023). This research made use of matplotlib, a Python library for publication quality graphics (Hunter 2007), NumPy (Harris et al. 2020) and SciPy (Virtanen et al. 2020).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_created":"2025-06-30T08:28:40Z","access_level":"open_access","content_type":"application/pdf","checksum":"a50a817b72f03534c6a867035b51e433","file_size":5758102,"success":1,"file_name":"2025_AstronomyAstrophysics_GurungLopez.pdf","relation":"main_file","file_id":"19933","creator":"dernst","date_updated":"2025-06-30T08:28:40Z"}],"date_published":"2025-06-01T00:00:00Z","external_id":{"isi":["001507317300003"],"arxiv":["2501.04077"]},"author":[{"last_name":"Gurung-López","full_name":"Gurung-López, Siddhartha","first_name":"Siddhartha"},{"full_name":"Byrohl, Chris","last_name":"Byrohl","first_name":"Chris"},{"full_name":"Gronke, Max","last_name":"Gronke","first_name":"Max"},{"first_name":"Daniele","full_name":"Spinoso, Daniele","last_name":"Spinoso"},{"orcid":"0000-0001-5586-6950","full_name":"Torralba Torregrosa, Alberto","last_name":"Torralba Torregrosa","id":"018f0249-0e87-11f0-b167-cbce08fbd541","first_name":"Alberto"},{"full_name":"Fernández-Soto, Alberto","last_name":"Fernández-Soto","first_name":"Alberto"},{"first_name":"Pablo","last_name":"Arnalte-Mur","full_name":"Arnalte-Mur, Pablo"},{"first_name":"Vicent J.","full_name":"Martínez, Vicent J.","last_name":"Martínez"}],"volume":698},{"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"OA_place":"publisher","isi":1,"_id":"19930","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"JoMa"}],"title":"Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies","date_updated":"2026-02-16T12:11:39Z","OA_type":"diamond","article_type":"original","month":"06","arxiv":1,"oa_version":"Published Version","type":"journal_article","publisher":"EDP Sciences","publication_status":"published","day":"01","citation":{"chicago":"Dottorini, D., A. Calabrò, L. Pentericci, Sara Mascia, M. Llerena, L. Napolitano, P. Santini, et al. “Evolution of the UV Slope of Galaxies at Cosmic Morning (z &#62; 4): The Properties of Extremely Blue Galaxies.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202453267\">https://doi.org/10.1051/0004-6361/202453267</a>.","apa":"Dottorini, D., Calabrò, A., Pentericci, L., Mascia, S., Llerena, M., Napolitano, L., … Pirzkal, N. (2025). Evolution of the UV slope of galaxies at cosmic morning (z &#62; 4): The properties of extremely blue galaxies. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202453267\">https://doi.org/10.1051/0004-6361/202453267</a>","mla":"Dottorini, D., et al. “Evolution of the UV Slope of Galaxies at Cosmic Morning (z &#62; 4): The Properties of Extremely Blue Galaxies.” <i>Astronomy &#38; Astrophysics</i>, vol. 698, A234, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202453267\">10.1051/0004-6361/202453267</a>.","ista":"Dottorini D, Calabrò A, Pentericci L, Mascia S, Llerena M, Napolitano L, Santini P, Roberts-Borsani G, Castellano M, Amorin R, Dickinson M, Fontana A, Hathi N, Hirschmann M, Koekemoer AM, Lucas RA, Merlin E, Morales A, Pacucci F, Wilkins S, Arrabal Haro P, Bagley M, Finkelstein SL, Kartaltepe J, Papovich C, Pirzkal N. 2025. Evolution of the UV slope of galaxies at cosmic morning (z &#62; 4): The properties of extremely blue galaxies. Astronomy &#38; Astrophysics. 698, A234.","ieee":"D. Dottorini <i>et al.</i>, “Evolution of the UV slope of galaxies at cosmic morning (z &#62; 4): The properties of extremely blue galaxies,” <i>Astronomy &#38; Astrophysics</i>, vol. 698. EDP Sciences, 2025.","short":"D. Dottorini, A. Calabrò, L. Pentericci, S. Mascia, M. Llerena, L. Napolitano, P. Santini, G. Roberts-Borsani, M. Castellano, R. Amorin, M. Dickinson, A. Fontana, N. Hathi, M. Hirschmann, A.M. Koekemoer, R.A. Lucas, E. Merlin, A. Morales, F. Pacucci, S. Wilkins, P. Arrabal Haro, M. Bagley, S.L. Finkelstein, J. Kartaltepe, C. Papovich, N. Pirzkal, Astronomy &#38; Astrophysics 698 (2025).","ama":"Dottorini D, Calabrò A, Pentericci L, et al. Evolution of the UV slope of galaxies at cosmic morning (z &#62; 4): The properties of extremely blue galaxies. <i>Astronomy &#38; Astrophysics</i>. 2025;698. doi:<a href=\"https://doi.org/10.1051/0004-6361/202453267\">10.1051/0004-6361/202453267</a>"},"date_created":"2025-06-29T22:01:15Z","quality_controlled":"1","scopus_import":"1","doi":"10.1051/0004-6361/202453267","intvolume":"       698","oa":1,"file_date_updated":"2025-06-30T08:22:08Z","abstract":[{"text":"We present an analysis of the UV continuum slope, β, using a sample of 726 galaxies with z > 4, selected from a mixture of JWST ERS, GTO, and GO observational programs. We considered only spectroscopic data obtained with the low-resolution (R ∼ 30 − 300) PRISM/CLEAR NIRSpec configuration. Studying the correlation between β and MUV, we find an overall decreasing trend, described by β = ( − 0.055 ± 0.017)MUV + ( − 2.98 ± 0.34). This is consistent with previous studies, where brighter galaxies show redder β values. However, when analyzing the trend in separate redshift bins, we find that at high redshift the relation becomes much flatter and is consistent with a flat slope within 1σ. Furthermore, we find that β tends to decrease with redshift, following β = ( − 0.075 ± 0.010)z + ( − 1.496 ± 0.056). This is consistent with most recent results showing a steepening of the spectra at higher z. We selected a sample of galaxies with extremely blue slopes (i.e., β < −2.6). Such slopes are steeper than predicted by stellar evolution models – even for dust-free, young, metal-poor populations – when the contribution of nebular emission is included. We selected 44 extremely blue galaxies (XBGs) and investigated the possible physical origin of their steep slopes by comparing them to a subsample of redder galaxies (matched in Δz = ±0.5 and ΔMUV = ±0.2). We find that XBGs have younger stellar populations, stronger ionization fields, lower dust attenuation, and lower but not pristine metallicity (∼10% Z⊙) compared to red galaxies. However, these properties alone cannot explain the extreme β values. Using indirect inference of Lyman continuum escape with the most recent models, we estimated the escape fraction fesc > 10% in at least 25% of the XBGs, whereas all the red sources exhibit much lower fesc values. A reduced nebular continuum contribution – resulting from either a high escape fraction or a bursty star formation history – is likely the origin of the extremely blue slopes.","lang":"eng"}],"ddc":["520"],"has_accepted_license":"1","article_number":"A234","article_processing_charge":"No","acknowledgement":"We acknowledges support from the INAF Large Grant for Extragalactic Surveys with JWST and from the PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU. PS acknowledges INAF Mini Grant 2022 “The evolution of passive galaxies through cosmic time”. Part of the research activities described in this paper were carried out with the contribution of the Next Generation EU funds within the National Recovery and Resilience Plan (PNRR), Mission 4 – Education and Research, Component 2 – From Research to Business (M4C2), Investment Line 3.1 – Strengthening and creation of Research Infrastructures, Project IR0000034 – “STILES – Strengthening the Italian Leadership in ELT and SKA”. RA acknowledges support of Grant project PID2023-147386NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU, and the Severo Ochoa grant CEX2021-001131-S funded by MCIN/AEI/10.13039/50110001103.","status":"public","volume":698,"author":[{"last_name":"Dottorini","full_name":"Dottorini, D.","first_name":"D."},{"last_name":"Calabrò","full_name":"Calabrò, A.","first_name":"A."},{"first_name":"L.","full_name":"Pentericci, L.","last_name":"Pentericci"},{"last_name":"Mascia","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","full_name":"Mascia, Sara","first_name":"Sara"},{"first_name":"M.","last_name":"Llerena","full_name":"Llerena, M."},{"last_name":"Napolitano","full_name":"Napolitano, L.","first_name":"L."},{"first_name":"P.","last_name":"Santini","full_name":"Santini, P."},{"last_name":"Roberts-Borsani","full_name":"Roberts-Borsani, G.","first_name":"G."},{"full_name":"Castellano, M.","last_name":"Castellano","first_name":"M."},{"full_name":"Amorin, R.","last_name":"Amorin","first_name":"R."},{"first_name":"M.","last_name":"Dickinson","full_name":"Dickinson, M."},{"first_name":"A.","last_name":"Fontana","full_name":"Fontana, A."},{"full_name":"Hathi, N.","last_name":"Hathi","first_name":"N."},{"first_name":"M.","full_name":"Hirschmann, M.","last_name":"Hirschmann"},{"first_name":"A. M.","full_name":"Koekemoer, A. M.","last_name":"Koekemoer"},{"first_name":"R. A.","last_name":"Lucas","full_name":"Lucas, R. A."},{"first_name":"E.","last_name":"Merlin","full_name":"Merlin, E."},{"first_name":"A.","last_name":"Morales","full_name":"Morales, A."},{"first_name":"F.","full_name":"Pacucci, F.","last_name":"Pacucci"},{"first_name":"S.","last_name":"Wilkins","full_name":"Wilkins, S."},{"first_name":"P.","last_name":"Arrabal Haro","full_name":"Arrabal Haro, P."},{"first_name":"M.","last_name":"Bagley","full_name":"Bagley, M."},{"full_name":"Finkelstein, S. L.","last_name":"Finkelstein","first_name":"S. L."},{"last_name":"Kartaltepe","full_name":"Kartaltepe, J.","first_name":"J."},{"last_name":"Papovich","full_name":"Papovich, C.","first_name":"C."},{"first_name":"N.","last_name":"Pirzkal","full_name":"Pirzkal, N."}],"external_id":{"arxiv":["2412.01623"],"isi":["001510826300019"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-06-01T00:00:00Z","file":[{"relation":"main_file","file_id":"19932","creator":"dernst","date_updated":"2025-06-30T08:22:08Z","date_created":"2025-06-30T08:22:08Z","content_type":"application/pdf","access_level":"open_access","checksum":"100f897d468de9d0113277c870035b62","file_size":2442076,"file_name":"2025_AstronomyAstrophysics_Dottorini.pdf","success":1}],"language":[{"iso":"eng"}],"publication":"Astronomy & Astrophysics","year":"2025"},{"ddc":["520"],"abstract":[{"text":"JWST observations have uncovered a new population of red, compact objects at high redshifts dubbed “little red dots” (LRDs), which typically show broad emission lines and are thought to be dusty active galactic nuclei (AGNs). Some of their other features, however, challenge the AGN explanation, such as prominent Balmer breaks and extremely faint or even missing metal high-ionization lines, X-ray, or radio emission, including in deep stacks. Time variability is another robust test of AGN activity. Here, we exploit the z = 7.045 multiply imaged LRD A2744-QSO1, which offers a particularly unique test of variability due to lensing-induced time delays between the three images spanning 22 yr (2.7 yr in the rest-frame), to investigate its photometric and spectroscopic variability. We find the equivalent widths (EWs) of the broad Hα and Hβ lines, which are independent of magnification and other systematics, to exhibit significant variations, of up to 18 ± 3% for Hα and up to 22 ± 8% in Hβ, on a timescale of 875 d (2.4 yr) in the rest-frame. This suggests that A2744-QSO1 is indeed an AGN. We find no significant photometric variability beyond the limiting systematic uncertainties, so it currently cannot be determined whether the EW variations are due to line-flux or continuum variability. These results are consistent with a typical damped random walk variability model for an AGN such as A2744-QSO1 (MBH = 4 × 107 M⊙) given the sparse sampling of the light curve with the available data. Our results therefore support the AGN interpretation of this LRD, and highlight the need for further photometric and spectroscopic monitoring in order to build a detailed and reliable light curve.","lang":"eng"}],"file_date_updated":"2025-06-30T08:44:24Z","oa":1,"article_processing_charge":"No","article_number":"A227","has_accepted_license":"1","scopus_import":"1","citation":{"mla":"Furtak, Lukas J., et al. “Investigating Photometric and Spectroscopic Variability in the Multiply Imaged Little Red Dot A2744-QSO1.” <i>Astronomy &#38; Astrophysics</i>, vol. 698, A227, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202554110\">10.1051/0004-6361/202554110</a>.","chicago":"Furtak, Lukas J., Amy R. Secunda, Jenny E. Greene, Adi Zitrin, Ivo Labbé, Miriam Golubchik, Rachel Bezanson, et al. “Investigating Photometric and Spectroscopic Variability in the Multiply Imaged Little Red Dot A2744-QSO1.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202554110\">https://doi.org/10.1051/0004-6361/202554110</a>.","apa":"Furtak, L. J., Secunda, A. R., Greene, J. E., Zitrin, A., Labbé, I., Golubchik, M., … Whitaker, K. E. (2025). Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202554110\">https://doi.org/10.1051/0004-6361/202554110</a>","ista":"Furtak LJ, Secunda AR, Greene JE, Zitrin A, Labbé I, Golubchik M, Bezanson R, Kokorev V, Atek H, Brammer GB, Chemerynska I, Cutler SE, Dayal P, Feldmann R, Fujimoto S, Glazebrook K, Leja J, Ma Y, Matthee JJ, Naidu RP, Nelson EJ, Oesch PA, Pan R, Price SH, Suess KA, Wang B, Weaver JR, Whitaker KE. 2025. Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. Astronomy &#38; Astrophysics. 698, A227.","ama":"Furtak LJ, Secunda AR, Greene JE, et al. Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. <i>Astronomy &#38; Astrophysics</i>. 2025;698. doi:<a href=\"https://doi.org/10.1051/0004-6361/202554110\">10.1051/0004-6361/202554110</a>","ieee":"L. J. Furtak <i>et al.</i>, “Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1,” <i>Astronomy &#38; Astrophysics</i>, vol. 698. EDP Sciences, 2025.","short":"L.J. Furtak, A.R. Secunda, J.E. Greene, A. Zitrin, I. Labbé, M. Golubchik, R. Bezanson, V. Kokorev, H. Atek, G.B. Brammer, I. Chemerynska, S.E. Cutler, P. Dayal, R. Feldmann, S. Fujimoto, K. Glazebrook, J. Leja, Y. Ma, J.J. Matthee, R.P. Naidu, E.J. Nelson, P.A. Oesch, R. Pan, S.H. Price, K.A. Suess, B. Wang, J.R. Weaver, K.E. Whitaker, Astronomy &#38; Astrophysics 698 (2025)."},"date_created":"2025-06-29T22:01:16Z","quality_controlled":"1","day":"01","intvolume":"       698","doi":"10.1051/0004-6361/202554110","language":[{"iso":"eng"}],"publication":"Astronomy & Astrophysics","year":"2025","acknowledgement":"We would like to thank Xihan Ji, Hannah Übler, and Roberto Maiolino, for cordial and useful discussions. The BGU lensing group acknowledges support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Israel Science Foundation Grant No. 864/23. P.D. warmly thanks the European Commission’s and University of Groningen’s CO-FUND Rosalind Franklin program. This work is based on observations obtained with the NASA/ESA/CSA JWST, namely programs GO-2756, -2561, -2883, -3538, -4111, and -3516, retrieved from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI). STScI is operated by the Association of Universities for Research in Astronomy, Inc. under NASA contract NAS 5-26555. The spectroscopy products presented herein, from JWST program GO-2561, were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. The data used in this work may be retrieved from the MAST archive at: http://dx.doi.org/10.17909/p7t7-te67. This work also makes use of the Center for Computational Astrophysics at the Flatiron Institute which is supported by the Simons Foundation. Support for JWST programs GO-2561, -4111, and -3516 was provided by NASA through grants from STScI. This research made use of Astropy, (http://www.astropy.org) a community-developed core Python package for Astronomy (Astropy Collaboration 2013, 2018) and Photutils, an Astropy package for detection and photometry of astronomical sources (Bradley et al. 2024), as well as the packages NumPy (van der Walt et al. 2011), SciPy (Virtanen et al. 2020), Matplotlib (Hunter 2007), and the MAAT Astronomy and Astrophysics tools for MATLAB (Ofek 2014).","status":"public","date_published":"2025-06-01T00:00:00Z","file":[{"relation":"main_file","file_id":"19934","creator":"dernst","date_updated":"2025-06-30T08:44:24Z","date_created":"2025-06-30T08:44:24Z","access_level":"open_access","content_type":"application/pdf","checksum":"567fa02a9791d489355ec75d02bb1cb9","file_size":1835865,"file_name":"2025_AstronomyAstrophysics_Furtak.pdf","success":1}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"isi":["001510826300017"],"arxiv":["2502.07875"]},"author":[{"first_name":"Lukas J.","full_name":"Furtak, Lukas J.","last_name":"Furtak"},{"full_name":"Secunda, Amy R.","last_name":"Secunda","first_name":"Amy R."},{"first_name":"Jenny E.","full_name":"Greene, Jenny E.","last_name":"Greene"},{"first_name":"Adi","full_name":"Zitrin, Adi","last_name":"Zitrin"},{"first_name":"Ivo","last_name":"Labbé","full_name":"Labbé, Ivo"},{"first_name":"Miriam","last_name":"Golubchik","full_name":"Golubchik, Miriam"},{"full_name":"Bezanson, Rachel","last_name":"Bezanson","first_name":"Rachel"},{"first_name":"Vasily","full_name":"Kokorev, Vasily","last_name":"Kokorev"},{"last_name":"Atek","full_name":"Atek, Hakim","first_name":"Hakim"},{"last_name":"Brammer","full_name":"Brammer, Gabriel B.","first_name":"Gabriel B."},{"last_name":"Chemerynska","full_name":"Chemerynska, Iryna","first_name":"Iryna"},{"first_name":"Sam E.","full_name":"Cutler, Sam E.","last_name":"Cutler"},{"last_name":"Dayal","full_name":"Dayal, Pratika","first_name":"Pratika"},{"last_name":"Feldmann","full_name":"Feldmann, Robert","first_name":"Robert"},{"first_name":"Seiji","full_name":"Fujimoto, Seiji","last_name":"Fujimoto"},{"first_name":"Karl","last_name":"Glazebrook","full_name":"Glazebrook, Karl"},{"full_name":"Leja, Joel","last_name":"Leja","first_name":"Joel"},{"full_name":"Ma, Yilun","last_name":"Ma","first_name":"Yilun"},{"full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J"},{"last_name":"Naidu","full_name":"Naidu, Rohan P.","first_name":"Rohan P."},{"first_name":"Erica J.","full_name":"Nelson, Erica J.","last_name":"Nelson"},{"last_name":"Oesch","full_name":"Oesch, Pascal A.","first_name":"Pascal A."},{"full_name":"Pan, Richard","last_name":"Pan","first_name":"Richard"},{"first_name":"Sedona H.","full_name":"Price, Sedona H.","last_name":"Price"},{"full_name":"Suess, Katherine A.","last_name":"Suess","first_name":"Katherine A."},{"first_name":"Bingjie","last_name":"Wang","full_name":"Wang, Bingjie"},{"last_name":"Weaver","full_name":"Weaver, John R.","first_name":"John R."},{"first_name":"Katherine E.","last_name":"Whitaker","full_name":"Whitaker, Katherine E."}],"volume":698,"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1","department":[{"_id":"JoMa"}],"date_updated":"2026-02-16T12:11:22Z","isi":1,"OA_place":"publisher","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"_id":"19931","arxiv":1,"type":"journal_article","publication_status":"published","publisher":"EDP Sciences","oa_version":"Published Version","OA_type":"diamond","month":"06","article_type":"original"},{"issue":"PLDI","publication":"Proceedings of the ACM on Programming Languages","page":"848-873","language":[{"iso":"eng"}],"year":"2025","acknowledgement":"We would like to thank the anonymous reviewers for their helpful feedback and Alex Summers\r\nfor insightful discussions. This work was funded in part by a Google PhD Fellowship for the first\r\nauthor.","status":"public","author":[{"last_name":"Spies","full_name":"Spies, Simon","first_name":"Simon"},{"first_name":"Niklas","last_name":"Mück","full_name":"Mück, Niklas"},{"full_name":"Zeng, Haoyi","last_name":"Zeng","first_name":"Haoyi"},{"last_name":"Sammler","id":"510d3901-2a03-11ee-914d-d9ae9011f0a7","full_name":"Sammler, Michael Joachim","first_name":"Michael Joachim"},{"full_name":"Lattuada, Andrea","last_name":"Lattuada","first_name":"Andrea"},{"first_name":"Peter","full_name":"Müller, Peter","last_name":"Müller"},{"last_name":"Dreyer","full_name":"Dreyer, Derek","first_name":"Derek"}],"volume":9,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-06-01T00:00:00Z","file":[{"file_size":843343,"success":1,"file_name":"2025_ProcACMProg_Spies.pdf","access_level":"open_access","content_type":"application/pdf","date_created":"2025-06-30T09:01:08Z","checksum":"6b72d84c10a10ba7cd1646e2c36dc1ff","date_updated":"2025-06-30T09:01:08Z","relation":"main_file","creator":"dernst","file_id":"19938"}],"file_date_updated":"2025-06-30T09:01:08Z","oa":1,"abstract":[{"lang":"eng","text":"The separation logic framework Iris has been built on the premise that all assertions are stable, meaning they unconditionally enjoy the famous frame rule. This gives Iris—and the numerous program logics that build on it—very modular reasoning principles. But stability also comes at a cost. It excludes a core feature of the Viper verifier family, heap-dependent expression assertions, which lift program expressions to the assertion level in order to reduce redundancy between code and specifications and better facilitate SMT-based automation.\r\nIn this paper, we bring heap-dependent expression assertions to Iris with Daenerys. To do so, we must first revisit the very core of Iris, extending it with a new form of unstable resources (and adapting the frame rule accordingly). On top, we then build a program logic with heap-dependent expression assertions and lay the foundations for connecting Iris to SMT solvers. We apply Daenerys to several case studies, including some that go beyond what Viper and Iris can do individually and others that benefit from the connection to SMT."}],"ddc":["000"],"has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","corr_author":"1","day":"01","scopus_import":"1","date_created":"2025-06-30T08:47:31Z","citation":{"ista":"Spies S, Mück N, Zeng H, Sammler MJ, Lattuada A, Müller P, Dreyer D. 2025. Destabilizing Iris. Proceedings of the ACM on Programming Languages. 9(PLDI), 848–873.","chicago":"Spies, Simon, Niklas Mück, Haoyi Zeng, Michael Joachim Sammler, Andrea Lattuada, Peter Müller, and Derek Dreyer. “Destabilizing Iris.” <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3729284\">https://doi.org/10.1145/3729284</a>.","apa":"Spies, S., Mück, N., Zeng, H., Sammler, M. J., Lattuada, A., Müller, P., &#38; Dreyer, D. (2025). Destabilizing Iris. <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3729284\">https://doi.org/10.1145/3729284</a>","mla":"Spies, Simon, et al. “Destabilizing Iris.” <i>Proceedings of the ACM on Programming Languages</i>, vol. 9, no. PLDI, Association for Computing Machinery, 2025, pp. 848–73, doi:<a href=\"https://doi.org/10.1145/3729284\">10.1145/3729284</a>.","short":"S. Spies, N. Mück, H. Zeng, M.J. Sammler, A. Lattuada, P. Müller, D. Dreyer, Proceedings of the ACM on Programming Languages 9 (2025) 848–873.","ieee":"S. Spies <i>et al.</i>, “Destabilizing Iris,” <i>Proceedings of the ACM on Programming Languages</i>, vol. 9, no. PLDI. Association for Computing Machinery, pp. 848–873, 2025.","ama":"Spies S, Mück N, Zeng H, et al. Destabilizing Iris. <i>Proceedings of the ACM on Programming Languages</i>. 2025;9(PLDI):848-873. doi:<a href=\"https://doi.org/10.1145/3729284\">10.1145/3729284</a>"},"quality_controlled":"1","doi":"10.1145/3729284","intvolume":"         9","oa_version":"Published Version","type":"journal_article","publisher":"Association for Computing Machinery","publication_status":"published","OA_type":"hybrid","article_type":"original","month":"06","department":[{"_id":"MiSa"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"Destabilizing Iris","date_updated":"2025-06-30T09:10:11Z","publication_identifier":{"eissn":["2475-1421"]},"OA_place":"publisher","_id":"19935"},{"date_updated":"2025-06-30T09:09:55Z","department":[{"_id":"MiSa"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"RefinedProsa: Connecting response-time analysis with C verification for interrupt-free schedulers","_id":"19936","OA_place":"publisher","publication_identifier":{"issn":["2475-1421"]},"type":"journal_article","publisher":"Association for Computing Machinery","publication_status":"published","oa_version":"Published Version","month":"06","article_type":"original","OA_type":"hybrid","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","abstract":[{"lang":"eng","text":"There has been a recent upsurge of interest in formal, machine-checked verification of timing guarantees for C implementations of real-time system schedulers. However, prior work has only considered tick-based schedulers, which enjoy a clearly defined notion of time: the time \"quantum\". In this work, we present a new approach to real-time systems verification for interrupt-free schedulers, which are commonly used in deeply embedded and resource-constrained systems but which do not enjoy a natural notion of periodic time. Our approach builds on and connects two recently developed Rocq-based systems—RefinedC (for foundational C verification) and Prosa (for verified response-time analysis)—adapting the former to reason about timed traces and the latter to reason about overheads. We apply the resulting system, which we call RefinedProsa, to verify Rössl, a simple yet representative, fixed-priority, non-preemptive, interrupt-free scheduler implemented in C."}],"ddc":["000"],"oa":1,"file_date_updated":"2025-06-30T09:08:05Z","intvolume":"         9","doi":"10.1145/3729249","date_created":"2025-06-30T08:47:58Z","quality_controlled":"1","citation":{"ista":"Bedarkar K, Elbeheiry L, Sammler MJ, Gäher L, Brandenburg B, Dreyer D, Garg D. 2025. RefinedProsa: Connecting response-time analysis with C verification for interrupt-free schedulers. Proceedings of the ACM on Programming Languages. 9(PLDI), 73–97.","mla":"Bedarkar, Kimaya, et al. “RefinedProsa: Connecting Response-Time Analysis with C Verification for Interrupt-Free Schedulers.” <i>Proceedings of the ACM on Programming Languages</i>, vol. 9, no. PLDI, Association for Computing Machinery, 2025, pp. 73–97, doi:<a href=\"https://doi.org/10.1145/3729249\">10.1145/3729249</a>.","chicago":"Bedarkar, Kimaya, Laila Elbeheiry, Michael Joachim Sammler, Lennard Gäher, Björn Brandenburg, Derek Dreyer, and Deepak Garg. “RefinedProsa: Connecting Response-Time Analysis with C Verification for Interrupt-Free Schedulers.” <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3729249\">https://doi.org/10.1145/3729249</a>.","apa":"Bedarkar, K., Elbeheiry, L., Sammler, M. J., Gäher, L., Brandenburg, B., Dreyer, D., &#38; Garg, D. (2025). RefinedProsa: Connecting response-time analysis with C verification for interrupt-free schedulers. <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3729249\">https://doi.org/10.1145/3729249</a>","ieee":"K. Bedarkar <i>et al.</i>, “RefinedProsa: Connecting response-time analysis with C verification for interrupt-free schedulers,” <i>Proceedings of the ACM on Programming Languages</i>, vol. 9, no. PLDI. Association for Computing Machinery, pp. 73–97, 2025.","short":"K. Bedarkar, L. Elbeheiry, M.J. Sammler, L. Gäher, B. Brandenburg, D. Dreyer, D. Garg, Proceedings of the ACM on Programming Languages 9 (2025) 73–97.","ama":"Bedarkar K, Elbeheiry L, Sammler MJ, et al. RefinedProsa: Connecting response-time analysis with C verification for interrupt-free schedulers. <i>Proceedings of the ACM on Programming Languages</i>. 2025;9(PLDI):73-97. doi:<a href=\"https://doi.org/10.1145/3729249\">10.1145/3729249</a>"},"scopus_import":"1","corr_author":"1","day":"13","year":"2025","page":"73-97","publication":"Proceedings of the ACM on Programming Languages","language":[{"iso":"eng"}],"issue":"PLDI","file":[{"checksum":"8c18d777feb342a7265c54b16205ec4c","content_type":"application/pdf","access_level":"open_access","date_created":"2025-06-30T09:08:05Z","success":1,"file_name":"2025_ProcACMProg_Bedarkar.pdf","file_size":1043790,"creator":"dernst","file_id":"19939","relation":"main_file","date_updated":"2025-06-30T09:08:05Z"}],"date_published":"2025-06-13T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":9,"author":[{"first_name":"Kimaya","full_name":"Bedarkar, Kimaya","last_name":"Bedarkar"},{"first_name":"Laila","full_name":"Elbeheiry, Laila","last_name":"Elbeheiry"},{"first_name":"Michael Joachim","full_name":"Sammler, Michael Joachim","last_name":"Sammler","id":"510d3901-2a03-11ee-914d-d9ae9011f0a7"},{"full_name":"Gäher, Lennard","last_name":"Gäher","first_name":"Lennard"},{"first_name":"Björn","full_name":"Brandenburg, Björn","last_name":"Brandenburg"},{"last_name":"Dreyer","full_name":"Dreyer, Derek","first_name":"Derek"},{"first_name":"Deepak","full_name":"Garg, Deepak","last_name":"Garg"}],"acknowledgement":"We would like to thank the anonymous reviewers for their helpful feedback.\r\nThis project has received funding from the European Research Council (ERC) under the European\r\nUnion’s Horizon 2020 research and innovation programme (grant agreement No 803111).","status":"public"},{"title":"Simplet-based signatures and approximation in simplicial complexes: Frequency, degree, and centrality","department":[{"_id":"HeEd"}],"date_updated":"2025-12-30T09:05:32Z","publication_identifier":{"issn":["0020-0255"]},"isi":1,"_id":"19937","ec_funded":1,"oa_version":"None","type":"journal_article","publisher":"Elsevier","publication_status":"published","OA_type":"closed access","article_type":"original","month":"11","project":[{"call_identifier":"H2020","grant_number":"788183","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425"},{"grant_number":"Z00342","call_identifier":"FWF","name":"Mathematics, Computer Science","_id":"268116B8-B435-11E9-9278-68D0E5697425"},{"name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35","call_identifier":"FWF","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"}],"abstract":[{"lang":"eng","text":"Simplets are elementary units within simplicial complexes and are fundamental for analyzing the structure of simplicial complexes. Previous efforts have mainly focused on accurately counting or approximating the number of simplets rather than studying their frequencies. However, analyzing simplet frequencies is more practical for large-scale simplicial complexes. This paper introduces the Simplet Frequency Distribution (SFD) vector, which enables the analysis of simplet frequencies in simplicial complexes. Additionally, we provide a bound on the sample complexity required to approximate the SFD vector using any uniform sampling-based algorithm accurately. We extend the definition of simplet frequency distribution to encompass simplices, allowing for the analysis of simplet frequencies within simplices of simplicial complexes. This paper introduces the Simplet Degree Vector (SDV) and the Simplet Degree Centrality (SDC), facilitating this analysis for each simplex. Furthermore, we present a bound on the sample complexity required for accurately approximating the SDV and SDC for a set of simplices using any uniform sampling-based algorithm. We also introduce algorithms for approximating SFD, geometric SFD, SDV, and SDC. We also validate the theoretical bounds with experiments on random simplicial complexes and demonstrate the practical application through a case study."}],"article_number":"122425","article_processing_charge":"No","day":"01","corr_author":"1","quality_controlled":"1","date_created":"2025-06-30T08:48:48Z","citation":{"mla":"Mahini, Mohammad, et al. “Simplet-Based Signatures and Approximation in Simplicial Complexes: Frequency, Degree, and Centrality.” <i>Information Sciences</i>, vol. 719, no. 11, 122425, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.ins.2025.122425\">10.1016/j.ins.2025.122425</a>.","apa":"Mahini, M., Beigy, H., Qadami, S., &#38; Saghafian, M. (2025). Simplet-based signatures and approximation in simplicial complexes: Frequency, degree, and centrality. <i>Information Sciences</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ins.2025.122425\">https://doi.org/10.1016/j.ins.2025.122425</a>","chicago":"Mahini, Mohammad, Hamid Beigy, Salman Qadami, and Morteza Saghafian. “Simplet-Based Signatures and Approximation in Simplicial Complexes: Frequency, Degree, and Centrality.” <i>Information Sciences</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.ins.2025.122425\">https://doi.org/10.1016/j.ins.2025.122425</a>.","ista":"Mahini M, Beigy H, Qadami S, Saghafian M. 2025. Simplet-based signatures and approximation in simplicial complexes: Frequency, degree, and centrality. Information Sciences. 719(11), 122425.","short":"M. Mahini, H. Beigy, S. Qadami, M. Saghafian, Information Sciences 719 (2025).","ieee":"M. Mahini, H. Beigy, S. Qadami, and M. Saghafian, “Simplet-based signatures and approximation in simplicial complexes: Frequency, degree, and centrality,” <i>Information Sciences</i>, vol. 719, no. 11. Elsevier, 2025.","ama":"Mahini M, Beigy H, Qadami S, Saghafian M. Simplet-based signatures and approximation in simplicial complexes: Frequency, degree, and centrality. <i>Information Sciences</i>. 2025;719(11). doi:<a href=\"https://doi.org/10.1016/j.ins.2025.122425\">10.1016/j.ins.2025.122425</a>"},"scopus_import":"1","doi":"10.1016/j.ins.2025.122425","intvolume":"       719","issue":"11","publication":"Information Sciences","language":[{"iso":"eng"}],"year":"2025","status":"public","acknowledgement":"The authors would like to thank the anonymous reviewers for their valuable comments and suggestions, which improved this paper.\r\nWork by the first and fourth authors is partially supported by the European Research Council (ERC), grant no. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), grant no. I 02979-N35.","volume":719,"author":[{"full_name":"Mahini, Mohammad","last_name":"Mahini","first_name":"Mohammad"},{"last_name":"Beigy","full_name":"Beigy, Hamid","first_name":"Hamid"},{"first_name":"Salman","full_name":"Qadami, Salman","last_name":"Qadami"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","last_name":"Saghafian","full_name":"Saghafian, Morteza","first_name":"Morteza"}],"external_id":{"isi":["001516170500002"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-11-01T00:00:00Z"},{"year":"2025","language":[{"iso":"eng"}],"publication":"The Astronomical Journal","issue":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_updated":"2025-07-08T06:40:54Z","file_id":"19975","creator":"dernst","relation":"main_file","file_name":"2025_AstronomicalJour_Cheng.pdf","success":1,"file_size":931173,"checksum":"144b0e46aa3dff0cdf8c6ee7d4fe2fe4","date_created":"2025-07-08T06:40:54Z","access_level":"open_access","content_type":"application/pdf"}],"date_published":"2025-07-01T00:00:00Z","author":[{"last_name":"Cheng","full_name":"Cheng, Sihao","first_name":"Sihao"},{"last_name":"Schlaufman","full_name":"Schlaufman, Kevin C.","first_name":"Kevin C."},{"first_name":"Ilaria","full_name":"Caiazzo, Ilaria","orcid":"0000-0002-4770-5388","last_name":"Caiazzo","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d"}],"external_id":{"isi":["001514518100001"],"arxiv":["2408.03985"]},"volume":170,"status":"public","acknowledgement":"We thank Jay Farihi, Guangwei Fu, J. J. Hermes, Mary Anne Limbach, and Daniel Thorngren for useful discussions. S.C. thanks Siyu Yao for her constant inspiration and encouragement. S.C. acknowledges the support of the Martin A. and Helen Chooljian Member Fund, funding from the Zurich Insurance Company, and the Fund for Natural Sciences at the Institute for Advanced Study. This work has made use of data from the European Space Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by the Gaia Data Processing and Analysis Consortium (DPAC; https://www.cosmos.esa.int/web/gaia/dpac/consortium). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. This work is based in part on observations made with the Spitzer Space Telescope, which is operated by the Jet Propulsion Laboratory, California Institute of Technology under a contract with NASA. This publication makes use of data products from the Wide-field Infrared Survey Explorer, which is a joint project of the University of California, Los Angeles, and the Jet Propulsion Laboratory/California Institute of Technology, funded by the National Aeronautics and Space Administration. This research has made use of the NASA Exoplanet Archive, which is operated by the California Institute of Technology, under contract with the National Aeronautics and Space Administration under the Exoplanet Exploration Program. This research has made use of NASA’s Astrophysics Data System.\r\nFacilities: ADS - , ESO:VISTA - European Southern Observatory's 4.1 meter Visible and Infrared Survey Telescope for Astronomy, Exoplanet Archive - , Gaia - , IRSA - , NEOWISE - , Spitzer - Spitzer Space Telescope satellite, UKIRT - United Kingdom Infrared Telescope, WISE - Wide-field Infrared Survey Explorer.\r\nSoftware: astropy (Astropy Collaboration et al. 2013, 2018, 2022), numpy (C. R. Harris et al. 2020), matplotlib (J. D. Hunter 2007), R (R Core Team 2024), SciPy (P. Virtanen et al. 2020).","article_processing_charge":"Yes","article_number":"47","has_accepted_license":"1","DOAJ_listed":"1","abstract":[{"text":"It has been suggested that giant planet occurrence peaks for stars with M* ≈ 3 M⊙ at a value a factor of 4 higher than observed for solar-mass stars. This population of giant planets predicted to frequently orbit main-sequence B stars at a ≈ 10 au is difficult to characterize during the few hundred million years while fusion persists in their host stars. By the time those stars become massive, young white dwarfs, any giant planets present would still be luminous as a consequence of their recent formation. From an initial sample of 2195 Gaia-identified massive, young white dwarfs, we use homogeneous Spitzer Infrared Array Camera (IRAC) photometry to search for evidence of unresolved giant planets. For 30 systems, these IRAC data provide sensitivity to objects with M ≲ 10 MJup, and we identify one candidate with M ≈ 4 MJup orbiting the white dwarf GALEX J071816.4+373139. Correcting for the possibility that some of the white dwarfs in our sample result from mergers, we find a giant planet occurrence  n GP = 0.11+0.13-0.07 for stars with initial masses M* ≳ 3 M⊙. Our occurrence inference is consistent with both the Doppler-inferred occurrence of giant planets orbiting M* ≈ 2 M⊙ giant stars and the theoretically predicted factor of 4 enhancement in the occurrence of giant planets orbiting M* ≈ 3 M⊙ stars relative to solar-mass stars. Future James Webb Space Telescope NIRCam observations of our sample would provide sensitivity to Saturn-mass planets and thereby a definitive estimate of the occurrence of giant planets orbiting stars with M* ≳ 3 M⊙.","lang":"eng"}],"ddc":["520"],"file_date_updated":"2025-07-08T06:40:54Z","oa":1,"intvolume":"       170","doi":"10.3847/1538-3881/addd21","scopus_import":"1","date_created":"2025-07-06T22:01:22Z","quality_controlled":"1","citation":{"ista":"Cheng S, Schlaufman KC, Caiazzo I. 2025. A candidate giant planet companion to the massive, young White Dwarf GALEX J071816.4+373139 informs the occurrence of giant planets orbiting B stars. The Astronomical Journal. 170(1), 47.","mla":"Cheng, Sihao, et al. “A Candidate Giant Planet Companion to the Massive, Young White Dwarf GALEX J071816.4+373139 Informs the Occurrence of Giant Planets Orbiting B Stars.” <i>The Astronomical Journal</i>, vol. 170, no. 1, 47, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-3881/addd21\">10.3847/1538-3881/addd21</a>.","chicago":"Cheng, Sihao, Kevin C. Schlaufman, and Ilaria Caiazzo. “A Candidate Giant Planet Companion to the Massive, Young White Dwarf GALEX J071816.4+373139 Informs the Occurrence of Giant Planets Orbiting B Stars.” <i>The Astronomical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-3881/addd21\">https://doi.org/10.3847/1538-3881/addd21</a>.","apa":"Cheng, S., Schlaufman, K. C., &#38; Caiazzo, I. (2025). A candidate giant planet companion to the massive, young White Dwarf GALEX J071816.4+373139 informs the occurrence of giant planets orbiting B stars. <i>The Astronomical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-3881/addd21\">https://doi.org/10.3847/1538-3881/addd21</a>","ama":"Cheng S, Schlaufman KC, Caiazzo I. A candidate giant planet companion to the massive, young White Dwarf GALEX J071816.4+373139 informs the occurrence of giant planets orbiting B stars. <i>The Astronomical Journal</i>. 2025;170(1). doi:<a href=\"https://doi.org/10.3847/1538-3881/addd21\">10.3847/1538-3881/addd21</a>","ieee":"S. Cheng, K. C. Schlaufman, and I. Caiazzo, “A candidate giant planet companion to the massive, young White Dwarf GALEX J071816.4+373139 informs the occurrence of giant planets orbiting B stars,” <i>The Astronomical Journal</i>, vol. 170, no. 1. IOP Publishing, 2025.","short":"S. Cheng, K.C. Schlaufman, I. Caiazzo, The Astronomical Journal 170 (2025)."},"day":"01","type":"journal_article","publisher":"IOP Publishing","publication_status":"published","oa_version":"Published Version","arxiv":1,"month":"07","article_type":"original","OA_type":"gold","date_updated":"2026-02-19T09:31:41Z","department":[{"_id":"IlCa"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"A candidate giant planet companion to the massive, young White Dwarf GALEX J071816.4+373139 informs the occurrence of giant planets orbiting B stars","_id":"19964","isi":1,"OA_place":"publisher","publication_identifier":{"issn":["0004-6256"],"eissn":["1538-3881"]}},{"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","ddc":["000"],"abstract":[{"lang":"eng","text":"Multiagent learning is challenging when agents face mixed-motivation interactions, where conflicts of interest arise as agents independently try to optimize their respective outcomes. Recent advancements in evolutionary game theory have identified a class of “zero-determinant” strategies, which confer an agent with significant unilateral control over outcomes in repeated games. Building on these insights, we present a comprehensive generalization of zero-determinant strategies to stochastic games, encompassing dynamic environments. We propose an algorithm that allows an agent to discover strategies enforcing predetermined linear (or approximately linear) payoff relationships. Of particular interest is the relationship in which both payoffs are equal, which serves as a proxy for fairness in symmetric games. We demonstrate that an agent can discover strategies enforcing such relationships through experience alone, without coordinating with an opponent. In finding and using such a strategy, an agent (“enforcer”) can incentivize optimal and equitable outcomes, circumventing potential exploitation. In particular, from the opponent’s viewpoint, the enforcer transforms a mixed-motivation problem into a cooperative problem, paving the way for more collaboration and fairness in multiagent systems."}],"oa":1,"file_date_updated":"2025-07-08T05:52:26Z","article_number":"e2319927121","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","date_created":"2025-07-06T22:01:23Z","citation":{"ista":"Mcavoy A, Sehwag UM, Hilbe C, Chatterjee K, Barfuss W, Su Q, Leonard NE, Plotkin JB. 2025. Unilateral incentive alignment in two-agent stochastic games. Proceedings of the National Academy of Sciences. 122(25), e2319927121.","chicago":"Mcavoy, Alex, Udari Madhushani Sehwag, Christian Hilbe, Krishnendu Chatterjee, Wolfram Barfuss, Qi Su, Naomi Ehrich Leonard, and Joshua B. Plotkin. “Unilateral Incentive Alignment in Two-Agent Stochastic Games.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2319927121\">https://doi.org/10.1073/pnas.2319927121</a>.","mla":"Mcavoy, Alex, et al. “Unilateral Incentive Alignment in Two-Agent Stochastic Games.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 25, e2319927121, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2319927121\">10.1073/pnas.2319927121</a>.","apa":"Mcavoy, A., Sehwag, U. M., Hilbe, C., Chatterjee, K., Barfuss, W., Su, Q., … Plotkin, J. B. (2025). Unilateral incentive alignment in two-agent stochastic games. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2319927121\">https://doi.org/10.1073/pnas.2319927121</a>","ieee":"A. Mcavoy <i>et al.</i>, “Unilateral incentive alignment in two-agent stochastic games,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 25. National Academy of Sciences, 2025.","short":"A. Mcavoy, U.M. Sehwag, C. Hilbe, K. Chatterjee, W. Barfuss, Q. Su, N.E. Leonard, J.B. Plotkin, Proceedings of the National Academy of Sciences 122 (2025).","ama":"Mcavoy A, Sehwag UM, Hilbe C, et al. Unilateral incentive alignment in two-agent stochastic games. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(25). doi:<a href=\"https://doi.org/10.1073/pnas.2319927121\">10.1073/pnas.2319927121</a>"},"quality_controlled":"1","scopus_import":"1","day":"24","intvolume":"       122","doi":"10.1073/pnas.2319927121","language":[{"iso":"eng"}],"publication":"Proceedings of the National Academy of Sciences","issue":"25","year":"2025","acknowledgement":"We gratefully acknowledge the support from the European Research Council (Starting Grant 850529: E-DIRECT) and the Max Planck Society (C.H.), the European Research Council (Consolidator Grant 863818: ForM-SMArt) (K.C.), the Shanghai Pujiang Program (No. 23PJ1405500) (Q.S.), the Army Research Office (Grant No. W911NF-18-1-0325) (N.E.L.), and the John Templeton Foundation (Grant No. 62281) (J.B.P.).","status":"public","date_published":"2025-06-24T00:00:00Z","file":[{"file_id":"19972","creator":"dernst","relation":"main_file","date_updated":"2025-07-08T05:52:26Z","checksum":"3b35befd959a3e37aa9080a64a6afaf3","date_created":"2025-07-08T05:52:26Z","access_level":"open_access","content_type":"application/pdf","file_name":"2025_PNAS_McAvoy.pdf","success":1,"file_size":29525932}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":122,"author":[{"full_name":"Mcavoy, Alex","last_name":"Mcavoy","first_name":"Alex"},{"last_name":"Sehwag","full_name":"Sehwag, Udari Madhushani","first_name":"Udari Madhushani"},{"id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","last_name":"Hilbe","orcid":"0000-0001-5116-955X","full_name":"Hilbe, Christian","first_name":"Christian"},{"last_name":"Chatterjee","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu"},{"last_name":"Barfuss","full_name":"Barfuss, Wolfram","first_name":"Wolfram"},{"first_name":"Qi","last_name":"Su","full_name":"Su, Qi"},{"first_name":"Naomi Ehrich","last_name":"Leonard","full_name":"Leonard, Naomi Ehrich"},{"full_name":"Plotkin, Joshua B.","last_name":"Plotkin","first_name":"Joshua B."}],"external_id":{"isi":["001522351900001"],"pmid":["40523172"]},"department":[{"_id":"KrCh"}],"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"title":"Unilateral incentive alignment in two-agent stochastic games","date_updated":"2025-09-30T13:47:14Z","OA_place":"publisher","isi":1,"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"_id":"19965","ec_funded":1,"pmid":1,"publication_status":"published","publisher":"National Academy of Sciences","type":"journal_article","oa_version":"Published Version","OA_type":"hybrid","month":"06","project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","grant_number":"863818"}],"article_type":"original"},{"status":"public","acknowledgement":"The authors acknowledge ERC n-AQUA for funding. S J acknowledges CNRS for funding. The authors thank Hummink for pipette supply and characterization. P R acknowledges funding from the European Union Horizon 2020 research and innovation program under the Marie Skodowska-Curie Grant Agreement No. 101034413.","volume":27,"external_id":{"isi":["001517731700001"]},"author":[{"first_name":"Simon","full_name":"Jouveshomme, Simon","last_name":"Jouveshomme"},{"first_name":"Mathieu","full_name":"Lizée, Mathieu","last_name":"Lizée"},{"id":"48c58128-57b0-11ee-9095-dc28fd97fc1d","last_name":"Robin","full_name":"Robin, Paul","orcid":"0000-0002-5728-9189","first_name":"Paul"},{"first_name":"Lydéric","last_name":"Bocquet","full_name":"Bocquet, Lydéric"}],"file":[{"date_updated":"2025-07-08T06:11:59Z","file_id":"19973","creator":"dernst","relation":"main_file","file_name":"2025_NewJourPhysics_Jouveshomme.pdf","success":1,"file_size":1296141,"checksum":"e0e11aa01c54b20ee6cdd1f6b999571f","date_created":"2025-07-08T06:11:59Z","access_level":"open_access","content_type":"application/pdf"}],"date_published":"2025-06-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","issue":"6","publication":"New Journal of Physics","language":[{"iso":"eng"}],"year":"2025","day":"01","quality_controlled":"1","citation":{"ama":"Jouveshomme S, Lizée M, Robin P, Bocquet L. Multiple ionic memories in asymmetric nanochannels revealed by mem-spectrometry. <i>New Journal of Physics</i>. 2025;27(6). doi:<a href=\"https://doi.org/10.1088/1367-2630/ade61b\">10.1088/1367-2630/ade61b</a>","short":"S. Jouveshomme, M. Lizée, P. Robin, L. Bocquet, New Journal of Physics 27 (2025).","ieee":"S. Jouveshomme, M. Lizée, P. Robin, and L. Bocquet, “Multiple ionic memories in asymmetric nanochannels revealed by mem-spectrometry,” <i>New Journal of Physics</i>, vol. 27, no. 6. IOP Publishing, 2025.","mla":"Jouveshomme, Simon, et al. “Multiple Ionic Memories in Asymmetric Nanochannels Revealed by Mem-Spectrometry.” <i>New Journal of Physics</i>, vol. 27, no. 6, 065001, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/1367-2630/ade61b\">10.1088/1367-2630/ade61b</a>.","apa":"Jouveshomme, S., Lizée, M., Robin, P., &#38; Bocquet, L. (2025). Multiple ionic memories in asymmetric nanochannels revealed by mem-spectrometry. <i>New Journal of Physics</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1367-2630/ade61b\">https://doi.org/10.1088/1367-2630/ade61b</a>","chicago":"Jouveshomme, Simon, Mathieu Lizée, Paul Robin, and Lydéric Bocquet. “Multiple Ionic Memories in Asymmetric Nanochannels Revealed by Mem-Spectrometry.” <i>New Journal of Physics</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/1367-2630/ade61b\">https://doi.org/10.1088/1367-2630/ade61b</a>.","ista":"Jouveshomme S, Lizée M, Robin P, Bocquet L. 2025. Multiple ionic memories in asymmetric nanochannels revealed by mem-spectrometry. New Journal of Physics. 27(6), 065001."},"date_created":"2025-07-06T22:01:23Z","scopus_import":"1","doi":"10.1088/1367-2630/ade61b","intvolume":"        27","oa":1,"file_date_updated":"2025-07-08T06:11:59Z","ddc":["530"],"abstract":[{"text":"Recently discovered nanofluidic memristors, have raised promises for the development of iontronics and neuromorphic computing with ions. Ionic memory effects are related to ion dynamics inside nanochannels, with timescales associated with the manifold physicochemical phenomena occurring at confined interfaces. Here, we explore experimentally the frequency-dependent current–voltage response of model nanochannels—namely glass nanopipettes—to investigate memory effects in ion transport. This characterisation, which we refer to as mem-spectrometry, highlights two characteristic frequencies, associated with short and long timescales of the order of 50 ms and 50 s in the present system. Whereas the former can be associated with ionic diffusion, very long timescales are difficult to explain with conventional transport phenomena. We develop a minimal model accounting for these mem-spectrometry results, pointing to surface charge regulation and ionic adsorption-desorption as possible origins for the long-term memory. Our work demonstrates the relevance of mem-spectrometry to highlight subtle ion transport properties in nanochannels, giving hereby new insights on the mechanisms governing ion transport and current rectification in charged conical nanopores.","lang":"eng"}],"DOAJ_listed":"1","has_accepted_license":"1","article_number":"065001","article_processing_charge":"Yes","OA_type":"gold","article_type":"original","month":"06","project":[{"grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"oa_version":"Published Version","type":"journal_article","publication_status":"published","publisher":"IOP Publishing","publication_identifier":{"eissn":["1367-2630"]},"OA_place":"publisher","isi":1,"_id":"19966","ec_funded":1,"title":"Multiple ionic memories in asymmetric nanochannels revealed by mem-spectrometry","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"EdHa"}],"date_updated":"2025-09-30T13:47:45Z"},{"_id":"19967","OA_place":"publisher","isi":1,"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"date_updated":"2026-02-16T12:12:15Z","department":[{"_id":"JoMa"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"The ionizing photon production efficiency of star-forming galaxies at z ∼ 4–10","month":"06","article_type":"original","OA_type":"diamond","publication_status":"published","publisher":"EDP Sciences","type":"journal_article","oa_version":"Published Version","arxiv":1,"intvolume":"       698","doi":"10.1051/0004-6361/202453251","date_created":"2025-07-06T22:01:23Z","citation":{"ista":"Llerena M, Pentericci L, Napolitano L, Mascia S, Amorín R, Calabrò A, Castellano M, Cleri NJ, Giavalisco M, Grogin NA, Hathi NP, Hirschmann M, Koekemoer AM, Nanayakkara T, Pacucci F, Shen L, Wilkins SM, Yoon I, Yung LYA, Bhatawdekar R, Lucas RA, Wang X, Arrabal Haro P, Bagley MB, Finkelstein SL, Kartaltepe JS, Merlin E, Papovich C, Pirzkal N, Santini P. 2025. The ionizing photon production efficiency of star-forming galaxies at z ∼ 4–10. Astronomy &#38; Astrophysics. 698, A302.","mla":"Llerena, M., et al. “The Ionizing Photon Production Efficiency of Star-Forming Galaxies at z ∼ 4–10.” <i>Astronomy &#38; Astrophysics</i>, vol. 698, A302, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202453251\">10.1051/0004-6361/202453251</a>.","apa":"Llerena, M., Pentericci, L., Napolitano, L., Mascia, S., Amorín, R., Calabrò, A., … Santini, P. (2025). The ionizing photon production efficiency of star-forming galaxies at z ∼ 4–10. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202453251\">https://doi.org/10.1051/0004-6361/202453251</a>","chicago":"Llerena, M., L. Pentericci, L. Napolitano, Sara Mascia, R. Amorín, A. Calabrò, M. Castellano, et al. “The Ionizing Photon Production Efficiency of Star-Forming Galaxies at z ∼ 4–10.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202453251\">https://doi.org/10.1051/0004-6361/202453251</a>.","ama":"Llerena M, Pentericci L, Napolitano L, et al. The ionizing photon production efficiency of star-forming galaxies at z ∼ 4–10. <i>Astronomy &#38; Astrophysics</i>. 2025;698. doi:<a href=\"https://doi.org/10.1051/0004-6361/202453251\">10.1051/0004-6361/202453251</a>","short":"M. Llerena, L. Pentericci, L. Napolitano, S. Mascia, R. Amorín, A. Calabrò, M. Castellano, N.J. Cleri, M. Giavalisco, N.A. Grogin, N.P. Hathi, M. Hirschmann, A.M. Koekemoer, T. Nanayakkara, F. Pacucci, L. Shen, S.M. Wilkins, I. Yoon, L.Y.A. Yung, R. Bhatawdekar, R.A. Lucas, X. Wang, P. Arrabal Haro, M.B. Bagley, S.L. Finkelstein, J.S. Kartaltepe, E. Merlin, C. Papovich, N. Pirzkal, P. Santini, Astronomy &#38; Astrophysics 698 (2025).","ieee":"M. Llerena <i>et al.</i>, “The ionizing photon production efficiency of star-forming galaxies at z ∼ 4–10,” <i>Astronomy &#38; Astrophysics</i>, vol. 698. EDP Sciences, 2025."},"quality_controlled":"1","scopus_import":"1","day":"20","article_number":"A302","article_processing_charge":"No","has_accepted_license":"1","ddc":["520"],"abstract":[{"lang":"eng","text":"Context. Investigating the ionizing emission of star-forming galaxies and the escape fraction of ionizing photons is critical to understanding their contribution to reionization and their impact on the surrounding environment. The number of ionizing photons available to reionize the intergalactic medium (IGM) depends on not only the abundance of galaxies but also their efficiency in producing ionizing photons (ξion). This quantity is thus fundamental to quantify the role of faint versus bright sources in driving this process, as we must assess their relative contribution to the total ionizing emissivity.\r\n\r\nAims. Our goal is to estimate the ξion using Balmer lines (Hα or Hβ) in a sample of 761 galaxies at 4 ≤ z ≤ 10 selected from different JWST spectroscopic surveys. We aim to determine the redshift evolution of ξion and the relation of ξion with the physical properties of the galaxies.\r\n\r\nMethods. We used the available HST and JWST photometry to perform a spectral energy distribution (SED) fitting in the sample to determine their physical properties and relate them with ξion. We used the BAGPIPES code for the SED fitting and assumed a delayed exponential model for the star formation history. We used the NIRSpec spectra from prism or grating configurations to estimate Balmer luminosities, and then constrained ξion values after dust correction.\r\n\r\nResults. We find a mean value of 1025.22 Hz erg−1 for ξion in the sample with an observed scatter of 0.42 dex. We find an increase in the median values of ξion with redshift from 1025.09 Hz erg−1 at z ∼ 4.18 to 1025.28 Hz erg−1 at z ∼ 7.14, confirming the redshift evolution of ξion found in other studies. Regarding the relation between ξion and physical properties, we find a decrease in ξion with increasing stellar mass, indicating that low-mass galaxies are efficient producers of ionizing photons. We also find an increase in ξion with increasing specific star formation rate (sSFR) and increasing UV absolute magnitude. This indicates that faint galaxies and galaxies with high sSFR are also efficient producers. We also investigated the relation of ξion with the rest-frame equivalent width (EW) of [OIII]λ5007 and find that galaxies with the higher EW([OIII]λ5007) are more efficient producers of ionizing photons, with the best fit leading to the relation log(ξion)  =  0.43 × log(EW[OIII])+23.99. Similarly, we find that galaxies with higher O32 = [OIII]λ5007/[OII]λλ3727,3729 and lower gas-phase metallicities (based on the R23 = ([OIII]λλ4959,5007+[OII]λλ3727,3729)/Hβ calibration) show higher ξion values."}],"oa":1,"file_date_updated":"2025-07-08T06:17:02Z","date_published":"2025-06-20T00:00:00Z","file":[{"access_level":"open_access","content_type":"application/pdf","date_created":"2025-07-08T06:17:02Z","checksum":"92745034d9448d38b6b0394407ae39a0","file_size":7557993,"file_name":"2025_AstronomyAstrophysics_Llerena.pdf","success":1,"relation":"main_file","creator":"dernst","file_id":"19974","date_updated":"2025-07-08T06:17:02Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":698,"author":[{"last_name":"Llerena","full_name":"Llerena, M.","first_name":"M."},{"first_name":"L.","full_name":"Pentericci, L.","last_name":"Pentericci"},{"first_name":"L.","last_name":"Napolitano","full_name":"Napolitano, L."},{"full_name":"Mascia, Sara","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","last_name":"Mascia","first_name":"Sara"},{"first_name":"R.","last_name":"Amorín","full_name":"Amorín, R."},{"first_name":"A.","last_name":"Calabrò","full_name":"Calabrò, A."},{"first_name":"M.","last_name":"Castellano","full_name":"Castellano, M."},{"first_name":"N. J.","last_name":"Cleri","full_name":"Cleri, N. J."},{"first_name":"M.","full_name":"Giavalisco, M.","last_name":"Giavalisco"},{"first_name":"N. A.","full_name":"Grogin, N. A.","last_name":"Grogin"},{"first_name":"N. P.","last_name":"Hathi","full_name":"Hathi, N. P."},{"full_name":"Hirschmann, M.","last_name":"Hirschmann","first_name":"M."},{"full_name":"Koekemoer, A. M.","last_name":"Koekemoer","first_name":"A. M."},{"last_name":"Nanayakkara","full_name":"Nanayakkara, T.","first_name":"T."},{"first_name":"F.","last_name":"Pacucci","full_name":"Pacucci, F."},{"full_name":"Shen, L.","last_name":"Shen","first_name":"L."},{"full_name":"Wilkins, S. M.","last_name":"Wilkins","first_name":"S. M."},{"first_name":"I.","full_name":"Yoon, I.","last_name":"Yoon"},{"full_name":"Yung, L. Y.A.","last_name":"Yung","first_name":"L. Y.A."},{"last_name":"Bhatawdekar","full_name":"Bhatawdekar, R.","first_name":"R."},{"first_name":"R. A.","full_name":"Lucas, R. A.","last_name":"Lucas"},{"first_name":"X.","last_name":"Wang","full_name":"Wang, X."},{"full_name":"Arrabal Haro, P.","last_name":"Arrabal Haro","first_name":"P."},{"first_name":"M. B.","full_name":"Bagley, M. B.","last_name":"Bagley"},{"first_name":"S. L.","full_name":"Finkelstein, S. L.","last_name":"Finkelstein"},{"first_name":"J. S.","full_name":"Kartaltepe, J. S.","last_name":"Kartaltepe"},{"last_name":"Merlin","full_name":"Merlin, E.","first_name":"E."},{"full_name":"Papovich, C.","last_name":"Papovich","first_name":"C."},{"full_name":"Pirzkal, N.","last_name":"Pirzkal","first_name":"N."},{"last_name":"Santini","full_name":"Santini, P.","first_name":"P."}],"external_id":{"arxiv":["2412.01358"],"isi":["001512479700026"]},"status":"public","acknowledgement":"We thank the anonymous referee for the detailed review and useful suggestions that helped to improve this paper. We wish to thank all our colleagues in the CEERS collaboration for their hard work and valuable contributions to this project. We thank Pietro Bergamini for providing us with the magnification factors for the lensed sources. MLl acknowledges support from the INAF Large Grant 2022 “Extragalactic Surveys with JWST” (PI L. Pentericci), the PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU, and INAF Mini-grant “Galaxies in the epoch of Reionization and their analogs at lower redshift” (PI M. Llerena). RA acknowledges support of grant PID2023-147386NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU, and the Severo Ochoa grant CEX2021-001131-S This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope (JWST). The JWST data presented in this article were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations analyzed are associated with program JWST-GO-3073 and can be accessed via DOI. We acknowledge support from INAF Mini-grant “Reionization and Fundamental Cosmology with High-Redshift Galaxies”. This work has made extensive use of Python packages astropy (Astropy Collaboration 2018), numpy (Harris et al. 2020), Matplotlib (Hunter 2007) and LiMe (Fernández et al. 2024).","year":"2025","language":[{"iso":"eng"}],"publication":"Astronomy & Astrophysics"},{"doi":"10.5465/AMPROC.2025.54bp","intvolume":"      2025","_id":"19968","publication_identifier":{"eissn":["2151-6561"],"issn":["0065-0668"]},"day":"17","scopus_import":"1","date_created":"2025-07-06T22:01:23Z","citation":{"ista":"Plata C, Casallas Garcia A. 2025. Machine learning analysis of the factors influencing university-industry collaborations. 85th Annual Meeting of the Academy of Management. AOM: Annual Meeting of the Academy of Management vol. 2025.","apa":"Plata, C., &#38; Casallas Garcia, A. (2025). Machine learning analysis of the factors influencing university-industry collaborations. In <i>85th Annual Meeting of the Academy of Management</i> (Vol. 2025). Copenhagen, Denmark: Academy of Management. <a href=\"https://doi.org/10.5465/AMPROC.2025.54bp\">https://doi.org/10.5465/AMPROC.2025.54bp</a>","chicago":"Plata, Carlos, and Alejandro Casallas Garcia. “Machine Learning Analysis of the Factors Influencing University-Industry Collaborations.” In <i>85th Annual Meeting of the Academy of Management</i>, Vol. 2025. Academy of Management, 2025. <a href=\"https://doi.org/10.5465/AMPROC.2025.54bp\">https://doi.org/10.5465/AMPROC.2025.54bp</a>.","mla":"Plata, Carlos, and Alejandro Casallas Garcia. “Machine Learning Analysis of the Factors Influencing University-Industry Collaborations.” <i>85th Annual Meeting of the Academy of Management</i>, vol. 2025, no. 1, Academy of Management, 2025, doi:<a href=\"https://doi.org/10.5465/AMPROC.2025.54bp\">10.5465/AMPROC.2025.54bp</a>.","ama":"Plata C, Casallas Garcia A. Machine learning analysis of the factors influencing university-industry collaborations. In: <i>85th Annual Meeting of the Academy of Management</i>. Vol 2025. Academy of Management; 2025. doi:<a href=\"https://doi.org/10.5465/AMPROC.2025.54bp\">10.5465/AMPROC.2025.54bp</a>","ieee":"C. Plata and A. Casallas Garcia, “Machine learning analysis of the factors influencing university-industry collaborations,” in <i>85th Annual Meeting of the Academy of Management</i>, Copenhagen, Denmark, 2025, vol. 2025, no. 1.","short":"C. Plata, A. Casallas Garcia, in:, 85th Annual Meeting of the Academy of Management, Academy of Management, 2025."},"quality_controlled":"1","article_processing_charge":"No","conference":{"end_date":"2025-07-29","name":"AOM: Annual Meeting of the Academy of Management","location":"Copenhagen, Denmark","start_date":"2025-07-25"},"date_updated":"2025-09-09T08:39:03Z","abstract":[{"text":"In the dynamic arena of innovation, the relations between academia and industry are a keystone for breakthroughs and practical applications. Yet, the groundwork of these pivotal University-Industry (U-I) partnerships remains covered in complexity. This paper delves into these intricate relations, unraveling the factors that help successful collaborations. Grounded in the Resource-Based Theory, our study transcends traditional analytical boundaries, leveraging a neural network model to understand a comprehensive dataset from the UK’s Higher Education Statistics Agency, SCIMAGO Rankings, and Clarivate Publications. This novel approach helps to make clear the interplay of academic load, administrative support, scientific output, and university rank in sculpting U-I collaboration dynamics. Our findings suggest that reduced academic load and robust administrative support significantly bolster U-I collaborations. However, the influence of scientific output and university ranking is more nuanced, challenging the common belief. High scientific output, while indicative of expertise, doesn't always align with industry goals. Similarly, while higher-ranked universities could attract more collaborations, the benefits are not universal. This paper not only contributes to a deeper understanding of U-I collaborations, but also provides actionable insights for university administrators, policymakers, and industry leaders. In a world where innovation is key, understanding these collaborative dynamics is crucial for fostering partnerships that push the boundaries of research and practical application.","lang":"eng"}],"title":"Machine learning analysis of the factors influencing university-industry collaborations","department":[{"_id":"CaMu"}],"author":[{"first_name":"Carlos","full_name":"Plata, Carlos","last_name":"Plata"},{"first_name":"Alejandro","orcid":"0000-0002-1988-5035","full_name":"Casallas Garcia, Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","last_name":"Casallas Garcia"}],"volume":2025,"month":"06","date_published":"2025-06-17T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"closed access","status":"public","year":"2025","oa_version":"None","type":"conference","publisher":"Academy of Management","publication_status":"published","issue":"1","language":[{"iso":"eng"}],"publication":"85th Annual Meeting of the Academy of Management"},{"arxiv":1,"oa_version":"Published Version","publisher":"Springer Nature","type":"journal_article","publication_status":"published","PlanS_conform":"1","OA_type":"hybrid","article_type":"original","project":[{"_id":"268A44D6-B435-11E9-9278-68D0E5697425","name":"Elastic Coordination for Scalable Machine Learning","call_identifier":"H2020","grant_number":"805223"}],"month":"09","title":"Near-optimal leader election in population protocols on graphs","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"DaAl"}],"date_updated":"2025-12-30T09:04:18Z","publication_identifier":{"issn":["0178-2770"],"eissn":["1432-0452"]},"isi":1,"OA_place":"publisher","ec_funded":1,"_id":"19969","page":"207-245","publication":"Distributed Computing","language":[{"iso":"eng"}],"year":"2025","acknowledgement":"We thank all anonymous reviewers for their helpful comments. We would also like to thank Jakob Solnerzik and Olivier Stietel for catching some errors in the proofs. Open Access funding enabled and organized by Projekt DEAL. We gratefully acknowledge funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 805223 ScaleML).","status":"public","author":[{"full_name":"Alistarh, Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","first_name":"Dan-Adrian"},{"first_name":"Joel","last_name":"Rybicki","id":"334EFD2E-F248-11E8-B48F-1D18A9856A87","full_name":"Rybicki, Joel","orcid":"0000-0002-6432-6646"},{"first_name":"Sasha","last_name":"Voitovych","full_name":"Voitovych, Sasha"}],"external_id":{"isi":["001518300400001"],"arxiv":["2205.12597"]},"volume":38,"date_published":"2025-09-01T00:00:00Z","file":[{"file_id":"20900","creator":"dernst","relation":"main_file","date_updated":"2025-12-30T09:03:55Z","checksum":"2789c0fdfb58f64930f05f6ac2b3ca61","date_created":"2025-12-30T09:03:55Z","content_type":"application/pdf","access_level":"open_access","file_name":"2025_DistributedComp_Alistarh.pdf","success":1,"file_size":770705}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2025-12-30T09:03:55Z","oa":1,"abstract":[{"lang":"eng","text":"In the stochastic population protocol model, we are given a connected graph with n nodes, and in every time step, a scheduler samples an edge of the graph uniformly at random and the nodes connected by this edge interact. A fundamental task in this model is stable leader election, in which all nodes start in an identical state and the aim is to reach a configuration in which (1)\r\nexactly one node is elected as leader and (2) this node remains as the unique leader no matter what sequence of interactions follows. On cliques, the complexity of this problem has recently been settled: time-optimal protocols stabilize in (n log n) expected steps using (log log n) states, whereas protocols that use O(1) states require (n2) expected steps. In this work, we investigate the complexity of stable leader election on graphs. We provide the first non-trivial time lower bounds on general graphs, showing that, when moving beyond cliques, the complexity of stable leader election can range from O(1) to (n3) expected steps. We describe a protocol that is time-optimal on many graph families, but uses polynomially-many states. In contrast, we give a near-time-optimal protocol that uses only O(log2 n) states that is at most a factor O(log n) slower. Finally, we observe that for many graphs the constant-state protocol of Beauquier et al. [OPODIS 2013] is at most a factor O(n log n) slower than the fast polynomial-state protocol, and among constant-state protocols, this protocol has near-optimal average case complexity on dense random graphs."}],"ddc":["510"],"has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","corr_author":"1","day":"01","scopus_import":"1","quality_controlled":"1","citation":{"ama":"Alistarh D-A, Rybicki J, Voitovych S. Near-optimal leader election in population protocols on graphs. <i>Distributed Computing</i>. 2025;38:207-245. doi:<a href=\"https://doi.org/10.1007/s00446-025-00487-7\">10.1007/s00446-025-00487-7</a>","short":"D.-A. Alistarh, J. Rybicki, S. Voitovych, Distributed Computing 38 (2025) 207–245.","ieee":"D.-A. Alistarh, J. Rybicki, and S. Voitovych, “Near-optimal leader election in population protocols on graphs,” <i>Distributed Computing</i>, vol. 38. Springer Nature, pp. 207–245, 2025.","chicago":"Alistarh, Dan-Adrian, Joel Rybicki, and Sasha Voitovych. “Near-Optimal Leader Election in Population Protocols on Graphs.” <i>Distributed Computing</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00446-025-00487-7\">https://doi.org/10.1007/s00446-025-00487-7</a>.","apa":"Alistarh, D.-A., Rybicki, J., &#38; Voitovych, S. (2025). Near-optimal leader election in population protocols on graphs. <i>Distributed Computing</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00446-025-00487-7\">https://doi.org/10.1007/s00446-025-00487-7</a>","mla":"Alistarh, Dan-Adrian, et al. “Near-Optimal Leader Election in Population Protocols on Graphs.” <i>Distributed Computing</i>, vol. 38, Springer Nature, 2025, pp. 207–45, doi:<a href=\"https://doi.org/10.1007/s00446-025-00487-7\">10.1007/s00446-025-00487-7</a>.","ista":"Alistarh D-A, Rybicki J, Voitovych S. 2025. Near-optimal leader election in population protocols on graphs. Distributed Computing. 38, 207–245."},"date_created":"2025-07-06T22:01:24Z","doi":"10.1007/s00446-025-00487-7","intvolume":"        38","related_material":{"record":[{"id":"11844","status":"public","relation":"earlier_version"}]}},{"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2412.15069"}],"OA_type":"green","project":[{"_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62","grant_number":"101019564","call_identifier":"H2020","name":"The design and evaluation of modern fully dynamic data structures"},{"grant_number":"Z00422","name":"Efficient algorithms","_id":"34def286-11ca-11ed-8bc3-da5948e1613c"},{"_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","name":"Static and Dynamic Hierarchical Graph Decompositions","grant_number":"I05982"},{"grant_number":"P33775","name":"Fast Algorithms for a Reactive Network Layer","_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe"}],"month":"01","arxiv":1,"type":"conference","publisher":"Society for Industrial and Applied Mathematics","publication_status":"published","oa_version":"Preprint","OA_place":"repository","publication_identifier":{"eisbn":["9781611978322"]},"ec_funded":1,"_id":"19982","title":"Fully dynamic approximate minimum cut in subpolynomial time per operation","department":[{"_id":"MoHe"}],"date_updated":"2025-12-29T12:30:04Z","acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’sHorizon 2020 research and innovation programme (MoDynStruct, No. 101019564) and the Austrian Science Fund(FWF) grant DOI 10.55776/Z422, grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775 with additional funding from the netidee SCIENCE Stiftung, 2020–2024.","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-01-07T00:00:00Z","external_id":{"arxiv":["2412.15069"]},"author":[{"full_name":"El-Hayek, Antoine","orcid":"0000-0003-4268-7368","id":"888a098e-fcac-11ee-aff7-d347be57b725","last_name":"El-Hayek","first_name":"Antoine"},{"first_name":"Monika H","full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630"},{"first_name":"Jason","full_name":"Li, Jason","last_name":"Li"}],"page":"750-784","language":[{"iso":"eng"}],"publication":"Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms","year":"2025","date_created":"2025-07-10T13:08:57Z","citation":{"ieee":"A. El-Hayek, M. Henzinger, and J. Li, “Fully dynamic approximate minimum cut in subpolynomial time per operation,” in <i>Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, New Orleans, LA, United States, 2025, pp. 750–784.","short":"A. El-Hayek, M. Henzinger, J. Li, in:, Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2025, pp. 750–784.","ama":"El-Hayek A, Henzinger M, Li J. Fully dynamic approximate minimum cut in subpolynomial time per operation. In: <i>Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for Industrial and Applied Mathematics; 2025:750-784. doi:<a href=\"https://doi.org/10.1137/1.9781611978322.22\">10.1137/1.9781611978322.22</a>","ista":"El-Hayek A, Henzinger M, Li J. 2025. Fully dynamic approximate minimum cut in subpolynomial time per operation. Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 750–784.","chicago":"El-Hayek, Antoine, Monika Henzinger, and Jason Li. “Fully Dynamic Approximate Minimum Cut in Subpolynomial Time per Operation.” In <i>Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 750–84. Society for Industrial and Applied Mathematics, 2025. <a href=\"https://doi.org/10.1137/1.9781611978322.22\">https://doi.org/10.1137/1.9781611978322.22</a>.","apa":"El-Hayek, A., Henzinger, M., &#38; Li, J. (2025). Fully dynamic approximate minimum cut in subpolynomial time per operation. In <i>Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (pp. 750–784). New Orleans, LA, United States: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611978322.22\">https://doi.org/10.1137/1.9781611978322.22</a>","mla":"El-Hayek, Antoine, et al. “Fully Dynamic Approximate Minimum Cut in Subpolynomial Time per Operation.” <i>Proceedings of the 2025 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Society for Industrial and Applied Mathematics, 2025, pp. 750–84, doi:<a href=\"https://doi.org/10.1137/1.9781611978322.22\">10.1137/1.9781611978322.22</a>."},"quality_controlled":"1","day":"07","corr_author":"1","doi":"10.1137/1.9781611978322.22","abstract":[{"text":"Dynamically maintaining the minimum cut in a graph G under edge insertions and deletion is a fundamental problem in dynamic graph algorithms for which no conditional lower bound on the time per operation exists. In an n-node graph the best known (1 + o (1))-approximate algorithm takes  update time [14]. If the minimum cut is guaranteed to be (log n )o (1), a deterministic exact algorithm with n o (1) update time exists [8].\r\nWe present the first fully dynamic algorithm for (1 + o (1))-approximate minimum cut with n o(1) update time. Our main technical contribution is to show that it suffices to consider small-volume cuts in suitably contracted graphs.","lang":"eng"}],"oa":1,"article_processing_charge":"No","conference":{"start_date":"2025-01-12","name":"SODA: Symposium on Discrete Algorithms","location":"New Orleans, LA, United States","end_date":"2025-01-15"}},{"article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","abstract":[{"text":"nspired by Richard Feynman’s 1959 lecture and the 1966 film Fantastic Voyage, the field of micro/nanorobots has evolved from science fiction to reality, with significant advancements in biomedical and environmental applications. Despite the rapid progress, the deployment of functional micro/nanorobots remains limited. This review of the technology roadmap identifies key challenges hindering their widespread use, focusing on propulsion mechanisms, fundamental theoretical aspects, collective behavior, material design, and embodied intelligence. We explore the current state of micro/nanorobot technology, with an emphasis on applications in biomedicine, environmental remediation, analytical sensing, and other industrial technological aspects. Additionally, we analyze issues related to scaling up production, commercialization, and regulatory frameworks that are crucial for transitioning from research to practical applications. We also emphasize the need for interdisciplinary collaboration to address both technical and nontechnical challenges, such as sustainability, ethics, and business considerations. Finally, we propose a roadmap for future research to accelerate the development of micro/nanorobots, positioning them as essential tools for addressing grand challenges and enhancing the quality of life.","lang":"eng"}],"ddc":["540"],"oa":1,"file_date_updated":"2025-12-30T09:07:31Z","intvolume":"        19","doi":"10.1021/acsnano.5c03911","citation":{"ista":"Ju X et al. 2025. Technology roadmap of micro/nanorobots. ACS Nano. 19(27), 24174–24334.","chicago":"Ju, Xiaohui, Chuanrui Chen, Cagatay M. Oral, Semih Sevim, Ramin Golestanian, Mengmeng Sun, Negin Bouzari, et al. “Technology Roadmap of Micro/Nanorobots.” <i>ACS Nano</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsnano.5c03911\">https://doi.org/10.1021/acsnano.5c03911</a>.","apa":"Ju, X., Chen, C., Oral, C. M., Sevim, S., Golestanian, R., Sun, M., … Pumera, M. (2025). Technology roadmap of micro/nanorobots. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.5c03911\">https://doi.org/10.1021/acsnano.5c03911</a>","mla":"Ju, Xiaohui, et al. “Technology Roadmap of Micro/Nanorobots.” <i>ACS Nano</i>, vol. 19, no. 27, American Chemical Society, 2025, pp. 24174–334, doi:<a href=\"https://doi.org/10.1021/acsnano.5c03911\">10.1021/acsnano.5c03911</a>.","ieee":"X. Ju <i>et al.</i>, “Technology roadmap of micro/nanorobots,” <i>ACS Nano</i>, vol. 19, no. 27. American Chemical Society, pp. 24174–24334, 2025.","short":"X. Ju, C. Chen, C.M. Oral, S. Sevim, R. Golestanian, M. Sun, N. Bouzari, X. Lin, M. Urso, J.S. Nam, Y. Cho, X. Peng, F.C. Landers, S. Yang, A. Adibi, N. Taz, R. Wittkowski, D. Ahmed, W. Wang, V. Magdanz, M. Medina-Sánchez, M. Guix, N. Bari, B. Behkam, R. Kapral, Y. Huang, J. Tang, B. Wang, K. Morozov, A. Leshansky, S.A. Abbasi, H. Choi, S. Ghosh, B. Borges Fernandes, G. Battaglia, P. Fischer, A. Ghosh, B. Jurado Sánchez, A. Escarpa, Q. Martinet, J.A. Palacci, E. Lauga, J. Moran, M.A. Ramos-Docampo, B. Städler, R.S. Herrera Restrepo, G. Yossifon, J.D. Nicholas, J. Ignés-Mullol, J. Puigmartí-Luis, Y. Liu, L.D. Zarzar, C.W. Shields, L. Li, S. Li, X. Ma, D.H. Gracias, O. Velev, S. Sánchez, M.J. Esplandiu, J. Simmchen, A. Lobosco, S. Misra, Z. Wu, J. Li, A. Kuhn, A. Nourhani, T. Maric, Z. Xiong, A. Aghakhani, Y. Mei, Y. Tu, F. Peng, E. Diller, M.S. Sakar, A. Sen, J. Law, Y. Sun, A. Pena-Francesch, K. Villa, H. Li, D.E. Fan, K. Liang, T.J. Huang, X.-Z. Chen, S. Tang, X. Zhang, J. Cui, H. Wang, W. Gao, V. Kumar Bandari, O.G. Schmidt, X. Wu, J. Guan, M. Sitti, B.J. Nelson, S. Pané, L. Zhang, H. Shahsavan, Q. He, I.-D. Kim, J. Wang, M. Pumera, ACS Nano 19 (2025) 24174–24334.","ama":"Ju X, Chen C, Oral CM, et al. Technology roadmap of micro/nanorobots. <i>ACS Nano</i>. 2025;19(27):24174-24334. doi:<a href=\"https://doi.org/10.1021/acsnano.5c03911\">10.1021/acsnano.5c03911</a>"},"quality_controlled":"1","date_created":"2025-07-10T14:53:27Z","scopus_import":"1","day":"27","year":"2025","page":"24174-24334","language":[{"iso":"eng"}],"publication":"ACS Nano","issue":"27","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-06-27T00:00:00Z","file":[{"date_created":"2025-12-30T09:07:31Z","access_level":"open_access","content_type":"application/pdf","checksum":"5f6034144bf9f649ff74fed01b04aa22","file_size":11892237,"file_name":"2025_ACSNano_Ju.pdf","success":1,"relation":"main_file","file_id":"20901","creator":"dernst","date_updated":"2025-12-30T09:07:31Z"}],"volume":19,"external_id":{"pmid":["40577644"],"isi":["001519731400001"]},"author":[{"first_name":"Xiaohui","full_name":"Ju, Xiaohui","last_name":"Ju"},{"last_name":"Chen","full_name":"Chen, Chuanrui","first_name":"Chuanrui"},{"last_name":"Oral","full_name":"Oral, Cagatay M.","first_name":"Cagatay M."},{"first_name":"Semih","full_name":"Sevim, Semih","last_name":"Sevim"},{"full_name":"Golestanian, Ramin","last_name":"Golestanian","first_name":"Ramin"},{"full_name":"Sun, Mengmeng","last_name":"Sun","first_name":"Mengmeng"},{"full_name":"Bouzari, Negin","last_name":"Bouzari","first_name":"Negin"},{"first_name":"Xiankun","full_name":"Lin, Xiankun","last_name":"Lin"},{"full_name":"Urso, Mario","last_name":"Urso","first_name":"Mario"},{"first_name":"Jong Seok","last_name":"Nam","full_name":"Nam, Jong Seok"},{"first_name":"Yujang","last_name":"Cho","full_name":"Cho, Yujang"},{"last_name":"Peng","full_name":"Peng, Xia","first_name":"Xia"},{"full_name":"Landers, Fabian C.","last_name":"Landers","first_name":"Fabian C."},{"first_name":"Shihao","last_name":"Yang","full_name":"Yang, Shihao"},{"full_name":"Adibi, Azin","last_name":"Adibi","first_name":"Azin"},{"full_name":"Taz, Nahid","last_name":"Taz","first_name":"Nahid"},{"last_name":"Wittkowski","full_name":"Wittkowski, Raphael","first_name":"Raphael"},{"first_name":"Daniel","full_name":"Ahmed, Daniel","last_name":"Ahmed"},{"full_name":"Wang, Wei","last_name":"Wang","first_name":"Wei"},{"first_name":"Veronika","last_name":"Magdanz","full_name":"Magdanz, Veronika"},{"first_name":"Mariana","full_name":"Medina-Sánchez, Mariana","last_name":"Medina-Sánchez"},{"first_name":"Maria","full_name":"Guix, Maria","last_name":"Guix"},{"last_name":"Bari","full_name":"Bari, Naimat","first_name":"Naimat"},{"last_name":"Behkam","full_name":"Behkam, Bahareh","first_name":"Bahareh"},{"last_name":"Kapral","full_name":"Kapral, Raymond","first_name":"Raymond"},{"first_name":"Yaxin","last_name":"Huang","full_name":"Huang, Yaxin"},{"full_name":"Tang, Jinyao","last_name":"Tang","first_name":"Jinyao"},{"first_name":"Ben","last_name":"Wang","full_name":"Wang, Ben"},{"last_name":"Morozov","full_name":"Morozov, Konstantin","first_name":"Konstantin"},{"first_name":"Alexander","full_name":"Leshansky, Alexander","last_name":"Leshansky"},{"last_name":"Abbasi","full_name":"Abbasi, Sarmad Ahmad","first_name":"Sarmad Ahmad"},{"first_name":"Hongsoo","full_name":"Choi, Hongsoo","last_name":"Choi"},{"last_name":"Ghosh","full_name":"Ghosh, Subhadip","first_name":"Subhadip"},{"first_name":"Bárbara","last_name":"Borges Fernandes","full_name":"Borges Fernandes, Bárbara"},{"last_name":"Battaglia","full_name":"Battaglia, Giuseppe","first_name":"Giuseppe"},{"full_name":"Fischer, Peer","last_name":"Fischer","first_name":"Peer"},{"last_name":"Ghosh","full_name":"Ghosh, Ambarish","first_name":"Ambarish"},{"first_name":"Beatriz","full_name":"Jurado Sánchez, Beatriz","last_name":"Jurado Sánchez"},{"last_name":"Escarpa","full_name":"Escarpa, Alberto","first_name":"Alberto"},{"first_name":"Quentin","full_name":"Martinet, Quentin","orcid":"0000-0002-2916-6632","id":"b37485a8-d343-11eb-a0e9-df8c484ef8ab","last_name":"Martinet"},{"full_name":"Palacci, Jérémie A","orcid":"0000-0002-7253-9465","last_name":"Palacci","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","first_name":"Jérémie A"},{"full_name":"Lauga, Eric","last_name":"Lauga","first_name":"Eric"},{"first_name":"Jeffrey","last_name":"Moran","full_name":"Moran, Jeffrey"},{"full_name":"Ramos-Docampo, Miguel A.","last_name":"Ramos-Docampo","first_name":"Miguel A."},{"last_name":"Städler","full_name":"Städler, Brigitte","first_name":"Brigitte"},{"last_name":"Herrera Restrepo","full_name":"Herrera Restrepo, Ramón Santiago","first_name":"Ramón Santiago"},{"full_name":"Yossifon, Gilad","last_name":"Yossifon","first_name":"Gilad"},{"full_name":"Nicholas, James D.","last_name":"Nicholas","first_name":"James D."},{"last_name":"Ignés-Mullol","full_name":"Ignés-Mullol, Jordi","first_name":"Jordi"},{"last_name":"Puigmartí-Luis","full_name":"Puigmartí-Luis, Josep","first_name":"Josep"},{"first_name":"Yutong","last_name":"Liu","full_name":"Liu, Yutong"},{"first_name":"Lauren D.","full_name":"Zarzar, Lauren D.","last_name":"Zarzar"},{"first_name":"C. Wyatt","last_name":"Shields","full_name":"Shields, C. Wyatt"},{"first_name":"Longqiu","last_name":"Li","full_name":"Li, Longqiu"},{"first_name":"Shanshan","last_name":"Li","full_name":"Li, Shanshan"},{"first_name":"Xing","last_name":"Ma","full_name":"Ma, Xing"},{"full_name":"Gracias, David H.","last_name":"Gracias","first_name":"David H."},{"first_name":"Orlin","full_name":"Velev, Orlin","last_name":"Velev"},{"first_name":"Samuel","full_name":"Sánchez, Samuel","last_name":"Sánchez"},{"full_name":"Esplandiu, Maria Jose","last_name":"Esplandiu","first_name":"Maria Jose"},{"full_name":"Simmchen, Juliane","last_name":"Simmchen","first_name":"Juliane"},{"first_name":"Antonio","last_name":"Lobosco","full_name":"Lobosco, Antonio"},{"first_name":"Sarthak","last_name":"Misra","full_name":"Misra, Sarthak"},{"first_name":"Zhiguang","last_name":"Wu","full_name":"Wu, Zhiguang"},{"full_name":"Li, Jinxing","last_name":"Li","first_name":"Jinxing"},{"first_name":"Alexander","full_name":"Kuhn, Alexander","last_name":"Kuhn"},{"first_name":"Amir","full_name":"Nourhani, Amir","last_name":"Nourhani"},{"last_name":"Maric","full_name":"Maric, Tijana","first_name":"Tijana"},{"full_name":"Xiong, Ze","last_name":"Xiong","first_name":"Ze"},{"full_name":"Aghakhani, Amirreza","last_name":"Aghakhani","first_name":"Amirreza"},{"last_name":"Mei","full_name":"Mei, Yongfeng","first_name":"Yongfeng"},{"full_name":"Tu, Yingfeng","last_name":"Tu","first_name":"Yingfeng"},{"first_name":"Fei","full_name":"Peng, Fei","last_name":"Peng"},{"first_name":"Eric","full_name":"Diller, Eric","last_name":"Diller"},{"last_name":"Sakar","full_name":"Sakar, Mahmut Selman","first_name":"Mahmut Selman"},{"first_name":"Ayusman","last_name":"Sen","full_name":"Sen, Ayusman"},{"full_name":"Law, Junhui","last_name":"Law","first_name":"Junhui"},{"last_name":"Sun","full_name":"Sun, Yu","first_name":"Yu"},{"full_name":"Pena-Francesch, Abdon","last_name":"Pena-Francesch","first_name":"Abdon"},{"full_name":"Villa, Katherine","last_name":"Villa","first_name":"Katherine"},{"last_name":"Li","full_name":"Li, Huaizhi","first_name":"Huaizhi"},{"first_name":"Donglei Emma","last_name":"Fan","full_name":"Fan, Donglei Emma"},{"first_name":"Kang","last_name":"Liang","full_name":"Liang, Kang"},{"first_name":"Tony Jun","last_name":"Huang","full_name":"Huang, Tony Jun"},{"full_name":"Chen, Xiang-Zhong","last_name":"Chen","first_name":"Xiang-Zhong"},{"full_name":"Tang, Songsong","last_name":"Tang","first_name":"Songsong"},{"full_name":"Zhang, Xueji","last_name":"Zhang","first_name":"Xueji"},{"full_name":"Cui, Jizhai","last_name":"Cui","first_name":"Jizhai"},{"first_name":"Hong","full_name":"Wang, Hong","last_name":"Wang"},{"last_name":"Gao","full_name":"Gao, Wei","first_name":"Wei"},{"last_name":"Kumar Bandari","full_name":"Kumar Bandari, Vineeth","first_name":"Vineeth"},{"full_name":"Schmidt, Oliver G.","last_name":"Schmidt","first_name":"Oliver G."},{"first_name":"Xianghua","full_name":"Wu, Xianghua","last_name":"Wu"},{"full_name":"Guan, Jianguo","last_name":"Guan","first_name":"Jianguo"},{"last_name":"Sitti","full_name":"Sitti, Metin","first_name":"Metin"},{"first_name":"Bradley J.","last_name":"Nelson","full_name":"Nelson, Bradley J."},{"full_name":"Pané, Salvador","last_name":"Pané","first_name":"Salvador"},{"first_name":"Li","full_name":"Zhang, Li","last_name":"Zhang"},{"last_name":"Shahsavan","full_name":"Shahsavan, Hamed","first_name":"Hamed"},{"last_name":"He","full_name":"He, Qiang","first_name":"Qiang"},{"first_name":"Il-Doo","last_name":"Kim","full_name":"Kim, Il-Doo"},{"first_name":"Joseph","last_name":"Wang","full_name":"Wang, Joseph"},{"first_name":"Martin","last_name":"Pumera","full_name":"Pumera, Martin"}],"acknowledgement":"The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies. Martin Pumera acknowledges the financial support of Grant Agency of the Czech Republic (EXPRO: 25-15484X). Xiaohui Ju, Xia Peng and Cagatay M. Oral acknowledge ERDF/ESF project TECHSCALE (No. CZ.02.01.01/00/22_008/0004587) for financial support. Xiaohui Ju acknowledges the financial support from Czech Grant Agency GACR standard grant No. 25-15996S. Salvador Pane, Fabian Landers and Semih Sevim acknowledge funding from the European Union's Horizon 2020 Proactive Open program under FETPROACT-EIC-05-2019 ANGIE (No. 952152) and the European Union’s Horizon Europe Research and Innovation Programme under the EVA project (GA no. 101047081).Li Zhang acknowledges funding support from the Hong Kong Research Grants Council (RGC) with grant numbers R4015-2, RFS2122-4S03, and STG1/E-401/23-N. Hamed Shahsavan acknowledges Natural Sciences and Engineering Research Council of Canada (NSERC). Cagatay M. Oral and Hamed Shahsavan were in part funded by the WIN-CEITEC BUT Joint Seed Funding Program. Qiang He and Xiankun Lin acknowledge the National Natural Science Foundation of China (22193033, U22A20346) and Heilongjiang Provincial Key R&D Program (2022ZX02C23) for providing financial support. Il-Doo Kim acknowledges the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2024-00435493). Ramin Golestanian acknowledges support from the Max Planck School Matter to Life and the MaxSynBio Consortium which are jointly funded by the Federal Ministry of Education and Research (BMBF) of Germany and the Max Planck Society. Bradley J. Nelson and Semih Sevim acknowledge funding from the Swiss National Science Foundation under SNSF-Sinergia project no. 198643. Raphael Wittkowski is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) − 535275785. Daniel Ahmed acknowledges the support provided by the European Research Council, as part of the European Union’s Horizon 2020 research and innovation program (grant agreement 853309, SONOBOTS) and Swiss National Science Foundation (SNSF) under the SNSF Project funding MINT 2022 grant agreement No. 213058. Daniel Ahmed also extends thanks to Zhiyuan Zhang, Mahmoud Medany, and Prajwal Agrawal for helpful discussions. Wei Wang acknowledges the National Natural Science Foundation of China (T2322006) and the Shenzhen Science and Technology Program (RCYX20210609103122038). Mariana Medina-Sánchez acknowledges the financial support received from the European Union’s Horizon 2020 research and innovation program (ERC Starting Grant Nr. 853609), the HORIZON-MSCA-2022-COFUND-101126600-SmartBRAIN3, and the Grant PID2023-148899OA-I00 funded by MICIU/AEI/ 10.13039/501100011033. Maria Guix acknowledges the financial support from the Spanish Ministry of Science (grants RYC2020-945030119-I and PID2023-151682NA-I00 funded by MCIN/ AEI /10.13039/501100011033/ and FEDER) and Unidades de Excelencia María de Maeztu 2021 CEX2021-001202-M. Bahareh Behkam and Naimat Kalim Bari acknowledge support from the National Science Foundation (CBET-2318093). Naimat Kalim Bari also gratefully acknowledges financial support from the Virginia Tech Presidential Postdoctoral Fellowship. Raymond Kapral acknowledges the Natural Sciences and Engineering Research Council of Canada. Giuseppe Battaglia, Subhadip Ghosh and Bárbara Borges Fernandes thank the European Research Council ChessTaG grant 769798 (G.B.); Ministry of Science and Innovation of Spain, Proyectos I+D+I PID2020-119914RBI00 and Proyectos I+D+I PID2023-149206OB-I00 and the Agencia de Gestión de Ayudas Universitarias y de Investigación (AGAUR) for the grant SGR 01538 and for SG fellowship (2022 BP 00214). Alexander Leshansky and Konstantin Morozov acknowledge the support of the Israel Science Foundation (ISF) via grant no. 2899/21. Alberto Escarpa and Beatriz Jurado Sánchez acknowledge support from The Spanish Ministry of Science, Innovation and Universities [Grant PID2023-152298NB-I00 funded by MCIN/AEI/10.13039/501100011033 and FEDER, UE (A.E, B. J. S), grant TED2021-132720B-I00, funded by MCIN/AEI/10.13039/501100011033 and the European Union “NextGenerationEU”/PRTR (A.E, B. J. S); grant CNS2023-144653 funded by MCIN/AEI/10.13039/ 501100011033 and the European Union “NextGenerationEU”/PRTR] and Junta de Comunidades de Castilla la Mancha (grant number SBPLY/23/180225/000058). Jeremie Palacci acknowledges support from the European Union through ERC grant (VULCAN, 101086998). Josep Puigmartí-Luis acknowledges the Agencia Estatal de Investigación (AEI) for the María de Maeztu, project no. CEX2021-001202-M, the Ministerio de Ciencia, Innovación y Universidades (Grant No. PID2020-116612RB-C33 funded by MCIN/AEI/10.13039/501100011033) and the Generalitat de Catalunya (2021 SGR 00270). James D. Nicholas, Jordi Ignés-Mullol, and Josep Puigmartí-Luis acknowledge support from the European Union’s Horizon Europe Research and Innovation Programme under the EVA project (GA no: 101047081). Josep Puigmartí-Luis and Jordi Ignés-Mullol acknowledge support from the European Union’s Horizon 2020 Proactive Open program under FETPROACT-EIC-05-2019 ANGIE (No. 952152). Jordi Ignés-Mullol also acknowledges the Ministerio de Ciencia, Innovación y Universidades (Grant No. PID2022-137713NB-C21 funded by MICIU/AEI/10.13039/501100011033). Lauren Zarzar and Yutong Liu acknowledge support from the US Army Research Office (Grant W911NF-18-1-0414). Longqiu Li acknowledges the National Natural Science Foundation of China (52125505, U23A20637) for providing financial support. Wyatt Shields acknowledges support from the National Science Foundation (NSF) through a CAREER grant (CBET 2143419). Xing Ma acknowledges the support from Shenzhen Science and Technology Program (RCJC20231211090000001). David H. Gracias acknowledges support from the NIH-NIBIB (R01EB017742). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Samuel Sánchez acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 and Horizon Europe research and innovation programmes (grants agreement No 866348, i-NanoSwarms), the CERCA program by the Generalitat de Catalunya, the project 2021 SGR 01606, and the \"Centro de Excelencia Severo Ochoa\" (Grant CEX2023-001282-S). Maria Jose Esplandiu acknowledges the Ministerio de Ciencia e Innovación of Spain (MICIN) through PID 2021-124568NB-I00 and TED2021-129898B-C21 project. Sarthak Misra and Antonio Lobosco acknowledge funding from European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme (Grant Nr. 866494, project-MAESTRO). Jinxing Li acknowledges support from the National Science Foundation under Award Nos. CMMI 2323917, ECCS-2216131, ECCS 2339495, ECCS-2334134, NIH NIBIB Trailblazer R21 Award, and Henry Ford Hospital + MSU Cancer Research Pilot Award. Ze Xiong acknowledges the financial support from the International S&T Cooperation Program of Shanghai (24490710900) and the start-up grant from ShanghaiTech University (2023F0209-000-02). Yongfeng Mei acknowledges the National Natural Science Foundation of China (62375054), Science and Technology Commission of Shanghai Municipality (24520750200, 24CL2900200), and Shanghai Talent Programs. Ayusman Sen thanks the National Science Foundation, the Air Force Office of Scientific Research, and the Sloan Foundation for their financial support. Abdon Pena-Francesch acknowledges support from the Air Force Office of Scientific Research under award number FA9550-24-1-0185. Katherine Villa acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (GA no. 101076680; PhotoSwim) and the support from the Spanish Ministry of Science (MCIN/AEI/10.13039/501100011033) and the European Union (Next generation EU/PRTR) through the Ramón y Cajal grant, RYC2021-031075-I. Kang Liang acknowledges support from the Australian Research Council (DP250101401 and FT220100479) and the National Breast Cancer Foundation, Australia (IIRS-22–104). Jizhai Cui acknowledges the National Key Technologies R&D Program of China (2022YFA1207000) and Shanghai Rising-Star Program (24QA2700700). Xiang-Zhong Chen acknowledges the National Natural Science Foundation of China (52473254) and the National Key Research and Development Program of China (2023YFB35070003)","status":"public","date_updated":"2025-12-30T09:07:44Z","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"JePa"}],"title":"Technology roadmap of micro/nanorobots","_id":"19998","pmid":1,"OA_place":"publisher","isi":1,"publication_identifier":{"eissn":["1936-086X"],"issn":["1936-0851"]},"publication_status":"published","type":"journal_article","publisher":"American Chemical Society","oa_version":"Published Version","project":[{"_id":"bdac72da-d553-11ed-ba76-eae56e802b74","grant_number":"101086998","name":"VULCAN: matter, powered from within"}],"month":"06","article_type":"review","OA_type":"hybrid","PlanS_conform":"1"},{"date_updated":"2025-07-14T08:30:06Z","department":[{"_id":"LeSa"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"title":"Visualization of a multi-turnover Cas9 after product release","_id":"20002","pmid":1,"OA_place":"publisher","publication_identifier":{"eissn":["2041-1723"]},"publication_status":"published","publisher":"Springer Nature","type":"journal_article","oa_version":"Published Version","month":"07","article_type":"original","PlanS_conform":"1","OA_type":"gold","article_processing_charge":"Yes","article_number":"5681","has_accepted_license":"1","DOAJ_listed":"1","ddc":["570"],"abstract":[{"lang":"eng","text":"While the most widely used CRISPR-Cas enzyme is the Cas9 endonuclease from Streptococcus pyogenes (Cas9), it exhibits single-turnover enzyme kinetics which leads to long residence times on product DNA. This blocks access to DNA repair machinery and acts as a major bottleneck during CRISPR-Cas9 gene editing. Cas9 can eventually be removed from the product by extrinsic factors, such as translocating polymerases, but the mechanisms contributing to Cas9 dissociation following cleavage remain poorly understood. Here, we employ truncated guide RNAs as a strategy to weaken PAM-distal nucleic acid interactions and promote faster enzyme turnover. Using kinetics-guided cryo-EM, we examine the conformational landscape of a multi-turnover Cas9, including the first detailed snapshots of Cas9 dissociating from product DNA. We discovered that while the PAM-distal product dissociates from Cas9 following cleavage, tight binding of the PAM-proximal product directly inhibits re-binding of new targets. Our work provides direct evidence as to why Cas9 acts as a single-turnover enzyme and will guide future Cas9 engineering efforts."}],"file_date_updated":"2025-07-14T08:28:25Z","oa":1,"intvolume":"        16","doi":"10.1038/s41467-025-60668-7","scopus_import":"1","date_created":"2025-07-13T22:01:21Z","quality_controlled":"1","citation":{"ista":"Kiernan K, Taylor DW. 2025. Visualization of a multi-turnover Cas9 after product release. Nature Communications. 16, 5681.","mla":"Kiernan, Kaitlyn, and David W. Taylor. “Visualization of a Multi-Turnover Cas9 after Product Release.” <i>Nature Communications</i>, vol. 16, 5681, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-60668-7\">10.1038/s41467-025-60668-7</a>.","apa":"Kiernan, K., &#38; Taylor, D. W. (2025). Visualization of a multi-turnover Cas9 after product release. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-60668-7\">https://doi.org/10.1038/s41467-025-60668-7</a>","chicago":"Kiernan, Kaitlyn, and David W. Taylor. “Visualization of a Multi-Turnover Cas9 after Product Release.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-60668-7\">https://doi.org/10.1038/s41467-025-60668-7</a>.","ama":"Kiernan K, Taylor DW. Visualization of a multi-turnover Cas9 after product release. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-60668-7\">10.1038/s41467-025-60668-7</a>","short":"K. Kiernan, D.W. Taylor, Nature Communications 16 (2025).","ieee":"K. Kiernan and D. W. Taylor, “Visualization of a multi-turnover Cas9 after product release,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025."},"day":"01","year":"2025","publication":"Nature Communications","language":[{"iso":"eng"}],"date_published":"2025-07-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"success":1,"file_name":"2025_NatureComm_Kiernan.pdf","file_size":6875712,"checksum":"fa9a1eaa7e2e60467768cbaed307aceb","access_level":"open_access","content_type":"application/pdf","date_created":"2025-07-14T08:28:25Z","date_updated":"2025-07-14T08:28:25Z","creator":"dernst","file_id":"20018","relation":"main_file"}],"external_id":{"pmid":["40593576"]},"author":[{"first_name":"Kaitlyn","full_name":"Kiernan, Kaitlyn","id":"91e8ab53-b70a-11ef-adcb-f779f833b451","last_name":"Kiernan"},{"last_name":"Taylor","full_name":"Taylor, David W.","first_name":"David W."}],"volume":16,"acknowledgement":"We thank Dr. Kenneth Johnson for assistance with kinetic analysis and helpful discussion as well as Dr. Jack Bravo and members of the Taylor lab for insightful comments on the manuscript. Data were collected at the Sauer Structural Biology Laboratory at the University of Texas at Austin. This work was supported by a National Institutes of Health grant R35GM138348 (to D.W.T.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Computational resources for this work were supported by the Welch Foundation grant F-1938 (to D.W.T.).","status":"public"},{"OA_place":"publisher","isi":1,"publication_identifier":{"eissn":["2542-4653"]},"_id":"20003","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"department":[{"_id":"MiLe"}],"title":"Lattice Bose polarons at strong coupling and quantum criticality","date_updated":"2025-09-30T14:00:26Z","OA_type":"diamond","PlanS_conform":"1","month":"07","article_type":"original","arxiv":1,"publisher":"SciPost Foundation","type":"journal_article","publication_status":"published","oa_version":"Published Version","citation":{"ama":"Al Hyder R, Colussi VE, Čufar M, Brand J, Recati A, Bruun GM. Lattice Bose polarons at strong coupling and quantum criticality. <i>Scipost Physics</i>. 2025;19(1). doi:<a href=\"https://doi.org/10.21468/SciPostPhys.19.1.002\">10.21468/SciPostPhys.19.1.002</a>","short":"R. Al Hyder, V.E. Colussi, M. Čufar, J. Brand, A. Recati, G.M. Bruun, Scipost Physics 19 (2025).","ieee":"R. Al Hyder, V. E. Colussi, M. Čufar, J. Brand, A. Recati, and G. M. Bruun, “Lattice Bose polarons at strong coupling and quantum criticality,” <i>Scipost Physics</i>, vol. 19, no. 1. SciPost Foundation, 2025.","ista":"Al Hyder R, Colussi VE, Čufar M, Brand J, Recati A, Bruun GM. 2025. Lattice Bose polarons at strong coupling and quantum criticality. Scipost Physics. 19(1), 002.","apa":"Al Hyder, R., Colussi, V. E., Čufar, M., Brand, J., Recati, A., &#38; Bruun, G. M. (2025). Lattice Bose polarons at strong coupling and quantum criticality. <i>Scipost Physics</i>. SciPost Foundation. <a href=\"https://doi.org/10.21468/SciPostPhys.19.1.002\">https://doi.org/10.21468/SciPostPhys.19.1.002</a>","chicago":"Al Hyder, Ragheed, Victor E. Colussi, Matija Čufar, Joachim Brand, Alessio Recati, and Georg M. Bruun. “Lattice Bose Polarons at Strong Coupling and Quantum Criticality.” <i>Scipost Physics</i>. SciPost Foundation, 2025. <a href=\"https://doi.org/10.21468/SciPostPhys.19.1.002\">https://doi.org/10.21468/SciPostPhys.19.1.002</a>.","mla":"Al Hyder, Ragheed, et al. “Lattice Bose Polarons at Strong Coupling and Quantum Criticality.” <i>Scipost Physics</i>, vol. 19, no. 1, 002, SciPost Foundation, 2025, doi:<a href=\"https://doi.org/10.21468/SciPostPhys.19.1.002\">10.21468/SciPostPhys.19.1.002</a>."},"quality_controlled":"1","date_created":"2025-07-13T22:01:22Z","scopus_import":"1","corr_author":"1","day":"01","intvolume":"        19","doi":"10.21468/SciPostPhys.19.1.002","ddc":["530"],"abstract":[{"text":"The problem of mobile impurities in quantum baths is of fundamental importance in many-body physics. There has recently been significant progress regarding our understanding of this due to cold atom experiments, but so far it has mainly been concerned with cases where the bath has no or only weak interactions, or the impurity interacts weakly with the bath. Here, we address this gap by developing a new theoretical framework for exploring a mobile impurity interacting strongly with a highly correlated bath of bosons in the quantum critical regime of a Mott insulator (MI) to superfluid (SF) quantum phase transition. Our framework is based on a powerful quantum Gutzwiller (QGW) description of the bosonic bath combined with diagrammatic field theory for the impurity-bath interactions. By resumming a selected class of diagrams to infinite order, a rich picture emerges where the impurity is dressed by the fundamental modes of the bath, which change character from gapped particle-hole excitations in the MI to Higgs and gapless Goldstone modes in the SF. This gives rise to the existence of several quasiparticle (polaron) branches with properties reflecting the strongly correlated environment. In particular, one polaron branch exhibits a sharp cusp in its energy, while a new ground-state polaron emerges at the O(2) quantum phase transition point for integer filling, which reflects the nonanalytic behavior at the transition and the appearance of the Goldstone mode in the SF phase. Smooth versions of these features are inherited in the polaron spectrum away from integer filling due to the influence of Mott physics on the bosonic bath. We furthermore compare our diagrammatic results with quantum Monte Carlo calculations, obtaining excellent agreement. This accuracy is quite remarkable for such a highly non-trivial case of strong interactions between the impurity and bosons in a maximally correlated quantum critical regime, and it establishes the utility of our framework. Finally, our results show how impurities can be used as quantum sensors and highlight fundamental differences between experiments performed at a fixed particle number or a fixed chemical potential.","lang":"eng"}],"oa":1,"file_date_updated":"2025-07-14T07:02:38Z","article_number":"002","article_processing_charge":"No","DOAJ_listed":"1","has_accepted_license":"1","status":"public","date_published":"2025-07-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file":[{"date_updated":"2025-07-14T07:02:38Z","creator":"dernst","file_id":"20014","relation":"main_file","success":1,"file_name":"2025_SciPostPhys_AlHyder.pdf","file_size":9769204,"checksum":"a2ce71aab685b7ea29e7abcf81e2fcc1","access_level":"open_access","content_type":"application/pdf","date_created":"2025-07-14T07:02:38Z"}],"volume":19,"external_id":{"arxiv":["2412.07597"],"isi":["001523515000002"]},"author":[{"full_name":"Al Hyder, Ragheed","last_name":"Al Hyder","id":"d1c405be-ae15-11ed-8510-ccf53278162e","first_name":"Ragheed"},{"first_name":"Victor E.","full_name":"Colussi, Victor E.","last_name":"Colussi"},{"first_name":"Matija","last_name":"Čufar","full_name":"Čufar, Matija"},{"first_name":"Joachim","full_name":"Brand, Joachim","last_name":"Brand"},{"first_name":"Alessio","last_name":"Recati","full_name":"Recati, Alessio"},{"first_name":"Georg M.","last_name":"Bruun","full_name":"Bruun, Georg M."}],"language":[{"iso":"eng"}],"publication":"Scipost Physics","issue":"1","year":"2025"}]