[{"department":[{"_id":"JoMa"}],"researchdata_availability":"no","language":[{"iso":"eng"}],"date_updated":"2026-08-12T09:28:30Z","arxiv":1,"oa":1,"author":[{"last_name":"Marques-Chaves","first_name":"R.","full_name":"Marques-Chaves, R."},{"first_name":"J.","full_name":"Álvarez-Márquez, J.","last_name":"Álvarez-Márquez"},{"full_name":"Colina, L.","first_name":"L.","last_name":"Colina"},{"last_name":"Kendrew","full_name":"Kendrew, S.","first_name":"S."},{"first_name":"Unknown","full_name":"Abdurro’Uf, Unknown","last_name":"Abdurro’Uf"},{"last_name":"Blanco-Prieto","full_name":"Blanco-Prieto, C.","first_name":"C."},{"first_name":"L. A.","full_name":"Boogaard, L. A.","last_name":"Boogaard"},{"last_name":"Castellano","first_name":"M.","full_name":"Castellano, M."},{"last_name":"Caputi","first_name":"K. I.","full_name":"Caputi, K. I."},{"last_name":"Crespo-Gómez","full_name":"Crespo-Gómez, A.","first_name":"A."},{"full_name":"Fontana, A.","first_name":"A.","last_name":"Fontana"},{"last_name":"Fudamoto","full_name":"Fudamoto, Y.","first_name":"Y."},{"full_name":"Fujimoto, S.","first_name":"S.","last_name":"Fujimoto"},{"last_name":"García-Marín","full_name":"García-Marín, M.","first_name":"M."},{"full_name":"Harikane, Y.","first_name":"Y.","last_name":"Harikane"},{"last_name":"Harish","first_name":"S.","full_name":"Harish, S."},{"last_name":"Hashimoto","first_name":"T.","full_name":"Hashimoto, T."},{"last_name":"Hsiao","full_name":"Hsiao, T.","first_name":"T."},{"id":"4053390a-6b68-11ef-9828-a3b8adef8d0a","first_name":"Edoardo","full_name":"Iani, Edoardo","orcid":"0000-0001-8386-3546","last_name":"Iani"},{"full_name":"Inoue, A. K.","first_name":"A. K.","last_name":"Inoue"},{"last_name":"Langeroodi","full_name":"Langeroodi, D.","first_name":"D."},{"last_name":"Lin","first_name":"R.","full_name":"Lin, R."},{"first_name":"J.","full_name":"Melinder, J.","last_name":"Melinder"},{"full_name":"Napolitano, L.","first_name":"L.","last_name":"Napolitano"},{"last_name":"Östlin","first_name":"G.","full_name":"Östlin, G."},{"first_name":"P. G.","full_name":"Pérez-González, P. G.","last_name":"Pérez-González"},{"last_name":"Prieto-Jiménez","first_name":"C.","full_name":"Prieto-Jiménez, C."},{"first_name":"P.","full_name":"Rinaldi, P.","last_name":"Rinaldi"},{"full_name":"Rodríguez Del Pino, B.","first_name":"B.","last_name":"Rodríguez Del Pino"},{"first_name":"P.","full_name":"Santini, P.","last_name":"Santini"},{"last_name":"Sugahara","full_name":"Sugahara, Y.","first_name":"Y."},{"first_name":"A.","full_name":"Varo-O’Ferrall, A.","last_name":"Varo-O’Ferrall"},{"last_name":"Wright","first_name":"G.","full_name":"Wright, G."},{"last_name":"Zavala","first_name":"J.","full_name":"Zavala, J."}],"ddc":["520"],"article_type":"original","intvolume":"       711","external_id":{"arxiv":["2602.02322"]},"citation":{"ieee":"R. Marques-Chaves <i>et al.</i>, “PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction,” <i>Astronomy &#38; Astrophysics</i>, vol. 711. EDP Sciences, 2026.","ista":"Marques-Chaves R, Álvarez-Márquez J, Colina L, Kendrew S, Abdurro’Uf U, Blanco-Prieto C, Boogaard LA, Castellano M, Caputi KI, Crespo-Gómez A, Fontana A, Fudamoto Y, Fujimoto S, García-Marín M, Harikane Y, Harish S, Hashimoto T, Hsiao T, Iani E, Inoue AK, Langeroodi D, Lin R, Melinder J, Napolitano L, Östlin G, Pérez-González PG, Prieto-Jiménez C, Rinaldi P, Rodríguez Del Pino B, Santini P, Sugahara Y, Varo-O’Ferrall A, Wright G, Zavala J. 2026. PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction. Astronomy &#38; Astrophysics. 711, A301.","apa":"Marques-Chaves, R., Álvarez-Márquez, J., Colina, L., Kendrew, S., Abdurro’Uf, U., Blanco-Prieto, C., … Zavala, J. (2026). PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202659281\">https://doi.org/10.1051/0004-6361/202659281</a>","ama":"Marques-Chaves R, Álvarez-Márquez J, Colina L, et al. PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction. <i>Astronomy &#38; Astrophysics</i>. 2026;711. doi:<a href=\"https://doi.org/10.1051/0004-6361/202659281\">10.1051/0004-6361/202659281</a>","chicago":"Marques-Chaves, R., J. Álvarez-Márquez, L. Colina, S. Kendrew, Unknown Abdurro’Uf, C. Blanco-Prieto, L. A. Boogaard, et al. “PRISMS: U37126, a Very Blue ISM-Naked Starburst at z = 10.255 with a Nearly 100% Lyman Continuum Escape Fraction.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202659281\">https://doi.org/10.1051/0004-6361/202659281</a>.","short":"R. Marques-Chaves, J. Álvarez-Márquez, L. Colina, S. Kendrew, U. Abdurro’Uf, C. Blanco-Prieto, L.A. Boogaard, M. Castellano, K.I. Caputi, A. Crespo-Gómez, A. Fontana, Y. Fudamoto, S. Fujimoto, M. García-Marín, Y. Harikane, S. Harish, T. Hashimoto, T. Hsiao, E. Iani, A.K. Inoue, D. Langeroodi, R. Lin, J. Melinder, L. Napolitano, G. Östlin, P.G. Pérez-González, C. Prieto-Jiménez, P. Rinaldi, B. Rodríguez Del Pino, P. Santini, Y. Sugahara, A. Varo-O’Ferrall, G. Wright, J. Zavala, Astronomy &#38; Astrophysics 711 (2026).","mla":"Marques-Chaves, R., et al. “PRISMS: U37126, a Very Blue ISM-Naked Starburst at z = 10.255 with a Nearly 100% Lyman Continuum Escape Fraction.” <i>Astronomy &#38; Astrophysics</i>, vol. 711, A301, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202659281\">10.1051/0004-6361/202659281</a>."},"fulldoi":"https://doi.org/10.1051/0004-6361/202659281","date_created":"2026-08-02T22:01:53Z","publisher":"EDP Sciences","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"_id":"22621","article_number":"A301","year":"2026","file":[{"creator":"dernst","access_level":"open_access","file_size":1127121,"file_id":"22634","date_updated":"2026-08-03T08:49:31Z","checksum":"8debbe56211a456539d8b3479f837b10","file_name":"2026_AstronomyAstrophysics_MarquesChaves.pdf","relation":"main_file","success":1,"date_created":"2026-08-03T08:49:31Z","content_type":"application/pdf"}],"type":"journal_article","status":"public","acknowledgement":"We thank the anonymous referee for the useful comments and suggestions. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program #8051. J.A.-M., C.P.-J., B.R.P. acknowledge support from grant PID2024-158856NA-I00, J.A.-M., L.C., C.P.-J., B.R.P. acknowledge support from grant PID2021-127718NB-100, P.G.P.-G. acknowledges support from grant PID2022-139567NB-I00 from the Spanish Ministry of Science and Innovation/State Agency of Research MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”. J.A.-M., L.C., C.P.-J., B.R.P., P.G.P.-G. acknowledge support by grant CSIC/BILATERALES2025/BIJSP25022. M.C. acknowledges INAF GO Grant 2024 “Revealing the nature of bright galaxies at cosmic dawn with deep JWST spectroscopy”. T.H. was supported by JSPS KAKENHI 25K00020. Y.H. acknowledges support from the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Scientific Research (24H00245), the JSPS Core-to-Core Program (JPJSCCA20210003), and the JSPS International Leading Research (22K21349). Y.F. is supported by JSPS KAKENHI Grant Numbers JP22K21349 and JP23K13149. D.L. was supported by research grants (VIL16599,VIL54489) from VILLUM FONDEN. P.S. acknowledges support from INAF RF2024 Large Grant “UNDUST: UNveiling the Dawn of the Universe with JWST” The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST; and from the European JWST archive (eJWST) operated by the ESDC. This research made use of Photutils, an Astropy package for detection and photometry of astronomical sources (Bradley et al. 2022).","date_published":"2026-07-24T00:00:00Z","OA_type":"diamond","title":"PRISMS: U37126, a very blue ISM-naked starburst at z = 10.255 with a nearly 100% Lyman continuum escape fraction","OA_place":"publisher","scopus_import":"1","doi":"10.1051/0004-6361/202659281","day":"24","file_date_updated":"2026-08-03T08:49:31Z","volume":711,"publication":"Astronomy & Astrophysics","abstract":[{"lang":"eng","text":"We present very deep (≈11 hours on-source) JWST/MIRI low-resolution spectroscopy of the rest-frame optical emission of U37126, a UV-bright (MUV ≃ −20) mildly lensed (μ ≃ 2.2) galaxy at z = 10.255. The continuum emission is well detected in the NIRSpec and MIRI spectra, but no nebular recombination or metal emission lines are observed (EW0 (Hβ+[O III]) ≤ 300 Å and EW0 (Hα) ≤ 400 Å at 3σ). Combined with the exceptionally blue UV continuum slope, βUV ≃ −2.9, and flat Balmer break, these constraints indicate a stellar population dominated by very young and massive stars with a strongly suppressed nebular contribution. Comparisons with synthetic stellar population models indicate that U37126 requires a very high ionizing photon production efficiency, log(ξion/Hz erg−1) ≃ 25.75, and a nearly unity Lyman continuum escape fraction, of fesc ≥ 86% (3σ) based on the Hα flux limit and fesc = 0.94 ± 0.06 derived independently from fitting the spectral energy distribution (SED). The best-fit SED yields a (delensed) stellar mass of M★ ≃ 107.8 M⊙ and a star formation rate SFR ≃ 10 M⊙ yr−1 (specific SFR ∼ 160 Gyr−1). Together with its very compact size, reff ≃ 61 pc, this yields a very high stellar mass and SFR surface densities, ΣM★ ≃ 3 × 103 M⊙ pc−2 and ΣSFR ≃ 400 M⊙ yr−1 kpc−2. Together with the lack of detectable nebular emission, these properties suggest that U37126 is undergoing a so-called interstellar medium-naked starburst phase, possibly driven by an extremely efficient gas-to-star conversion followed by strong feedback that has cleared the remaining gas from its stellar core, which allowed most Lyman continuum photons to escape. Finally, we show that even a small fraction of galaxies such as U37126 (≃3–6%), with an extreme Lyman continuum production and escape, might contribute disproportionately (≃50–100%) to the ionizing photon budget during cosmic reionization."}],"das_tickbox":"0","PlanS_conform":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","publication_status":"published","month":"07","quality_controlled":"1","has_accepted_license":"1","article_processing_charge":"No","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]}},{"language":[{"iso":"eng"}],"date_updated":"2026-08-12T09:29:13Z","department":[{"_id":"LiBu"}],"ddc":["520"],"author":[{"full_name":"Breton, S. N.","first_name":"S. N.","last_name":"Breton"},{"last_name":"Pezzotti","full_name":"Pezzotti, C.","first_name":"C."},{"first_name":"S.","full_name":"Mathis, S.","last_name":"Mathis"},{"last_name":"Bugnet","orcid":"0000-0003-0142-4000","first_name":"Lisa Annabelle","full_name":"Bugnet, Lisa Annabelle","id":"d9edb345-f866-11ec-9b37-d119b5234501"},{"first_name":"M. P.","full_name":"Di Mauro, M. P.","last_name":"Di Mauro"},{"first_name":"J.","full_name":"Joergensen, J.","last_name":"Joergensen"},{"last_name":"Zwintz","full_name":"Zwintz, K.","first_name":"K."},{"last_name":"Lanza","full_name":"Lanza, A. F.","first_name":"A. F."}],"arxiv":1,"oa":1,"fulldoi":"https://doi.org/10.1051/0004-6361/202659309","citation":{"ieee":"S. N. Breton <i>et al.</i>, “Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type stars,” <i>Astronomy &#38; Astrophysics</i>, vol. 707. EDP Sciences, 2026.","ista":"Breton SN, Pezzotti C, Mathis S, Bugnet LA, Di Mauro MP, Joergensen J, Zwintz K, Lanza AF. 2026. Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type stars. Astronomy &#38; Astrophysics. 707, L16.","apa":"Breton, S. N., Pezzotti, C., Mathis, S., Bugnet, L. A., Di Mauro, M. P., Joergensen, J., … Lanza, A. F. (2026). Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type stars. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202659309\">https://doi.org/10.1051/0004-6361/202659309</a>","ama":"Breton SN, Pezzotti C, Mathis S, et al. Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type stars. <i>Astronomy &#38; Astrophysics</i>. 2026;707. doi:<a href=\"https://doi.org/10.1051/0004-6361/202659309\">10.1051/0004-6361/202659309</a>","short":"S.N. Breton, C. Pezzotti, S. Mathis, L.A. Bugnet, M.P. Di Mauro, J. Joergensen, K. Zwintz, A.F. Lanza, Astronomy &#38; Astrophysics 707 (2026).","chicago":"Breton, S. N., C. Pezzotti, S. Mathis, Lisa Annabelle Bugnet, M. P. Di Mauro, J. Joergensen, K. Zwintz, and A. F. Lanza. “Core-Envelope Coupling of Gravito-Inertial Waves in Pre-Main-Sequence Solar-Type Stars.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202659309\">https://doi.org/10.1051/0004-6361/202659309</a>.","mla":"Breton, S. N., et al. “Core-Envelope Coupling of Gravito-Inertial Waves in Pre-Main-Sequence Solar-Type Stars.” <i>Astronomy &#38; Astrophysics</i>, vol. 707, L16, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202659309\">10.1051/0004-6361/202659309</a>."},"external_id":{"arxiv":["2603.01979"]},"intvolume":"       707","article_type":"letter_editor","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publisher":"EDP Sciences","DOAJ_listed":"1","date_created":"2026-04-05T22:01:32Z","date_published":"2026-03-01T00:00:00Z","acknowledgement":"The authors want to thank the anonymous referee for useful comments. SNB acknowledges support from PLATO ASI-INAF agreement no. 2022-28-HH.0 “PLATO Fase D”. SNB and AFL acknowledge support from the INAF grant MASTODINT. CP thanks the Belgian Federal Science Policy Office (BELSPO) for the financial support in the framework of the PRODEX Program of the European Space Agency (ESA) under contract number 4000141194. S.M acknowledges support from the CNES GOLF-SOHO and PLATO grants at CEA/DAp. LB and SM gratefully acknowledge support from the European Research Council (ERC) under the Horizon Europe programme (LB: Calcifer; Starting Grant agreement N°101165631; SM: 4D-STAR; Synergy Grant agreement N°101071505). While partially funded by the European Union, views and opinions expressed are, however, those of the authors only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. The authors acknowledge G. Buldgen, H. Dhouib, and M.A. Dupret for fruitful discussions.","status":"public","type":"journal_article","year":"2026","file":[{"file_size":1535506,"checksum":"a7fd798bf450d67d4166fdf54ff2c70c","date_updated":"2026-04-07T09:20:02Z","file_id":"21666","file_name":"2026_AstronomyAstrophysics_Breton.pdf","access_level":"open_access","creator":"dernst","date_created":"2026-04-07T09:20:02Z","content_type":"application/pdf","success":1,"relation":"main_file"}],"article_number":"L16","_id":"21659","scopus_import":"1","OA_place":"publisher","title":"Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type stars","OA_type":"diamond","oa_version":"Published Version","PlanS_conform":"1","abstract":[{"text":"The recent detection of solar equatorial Rossby waves has renewed interest in the study of gravito-inertial waves propagating in the convective envelope of solar-type stars. In particular, the ability of these envelope gravito-inertial modes to couple with those trapped in the radiative interior could open up new opportunities for probing the deep-layer dynamics of solar-type stars. The possibility for such a coupling to occur is particularly favoured among pre-main-sequence (PMS) solar-type stars. Indeed, due to the contraction of the protostellar object, they are able to reach high rotation frequencies before nuclear reactions are ignited and magnetic braking becomes the driving mechanism for their rotational evolution. In this work, we studied the coupling between the envelope inertial waves and the radiative interior g modes in PMS stars, focussing on the case of prograde dipolar modes. We considered the cases of 0.5 M⊙ and 1 M⊙ PMS models, each with three different scenarios of rotational evolution. We show that for stars that have formed with a sufficient amount of angular momentum, this coupling can occur in frequency ranges that are accessible to space-borne photometry, creating inertial dips in the period spacing pattern. Using an asymptotic analysis, we characterised the shape of these inertial dips to show that they depend on rotation and on the stiffness of the convective-radiative interface.","lang":"eng"}],"file_date_updated":"2026-04-07T09:20:02Z","volume":707,"publication":"Astronomy & Astrophysics","doi":"10.1051/0004-6361/202659309","day":"01","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"has_accepted_license":"1","article_processing_charge":"No","quality_controlled":"1","month":"03","publication_status":"published","project":[{"_id":"914d8549-16d5-11f0-9cad-bbe6324c93a9","name":"Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology","grant_number":"101165631"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_created":"2026-04-26T22:01:46Z","publisher":"Elsevier","corr_author":"1","fulldoi":"https://doi.org/10.1016/j.gde.2026.102472","citation":{"short":"E. Mascolo, R.E. Körei, N.O. Borst, N.H. Barton, J. Crocker, G. Tkačik, Current Opinion in Genetics &#38; Development 98 (2026).","chicago":"Mascolo, Elia, Reka E Körei, Noa O. Borst, Nicholas H Barton, Justin Crocker, and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory and Future Challenges.” <i>Current Opinion in Genetics &#38; Development</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.gde.2026.102472\">https://doi.org/10.1016/j.gde.2026.102472</a>.","mla":"Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory and Future Challenges.” <i>Current Opinion in Genetics &#38; Development</i>, vol. 98, 102472, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102472\">10.1016/j.gde.2026.102472</a>.","ieee":"E. Mascolo, R. E. Körei, N. O. Borst, N. H. Barton, J. Crocker, and G. Tkačik, “Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges,” <i>Current Opinion in Genetics &#38; Development</i>, vol. 98. Elsevier, 2026.","ista":"Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. 2026. Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. Current Opinion in Genetics &#38; Development. 98, 102472.","ama":"Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. <i>Current Opinion in Genetics &#38; Development</i>. 2026;98. doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102472\">10.1016/j.gde.2026.102472</a>","apa":"Mascolo, E., Körei, R. E., Borst, N. O., Barton, N. H., Crocker, J., &#38; Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. <i>Current Opinion in Genetics &#38; Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2026.102472\">https://doi.org/10.1016/j.gde.2026.102472</a>"},"article_type":"review","intvolume":"        98","author":[{"first_name":"Elia","full_name":"Mascolo, Elia","orcid":"0000-0003-2977-7844","id":"776a6ed0-a053-11f0-8635-80b95e0e0d53","last_name":"Mascolo"},{"last_name":"Körei","first_name":"Reka E","full_name":"Körei, Reka E","id":"50FDE43E-AA30-11E9-A72B-8A12E6697425"},{"last_name":"Borst","full_name":"Borst, Noa O.","first_name":"Noa O."},{"last_name":"Barton","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Justin","full_name":"Crocker, Justin","last_name":"Crocker"},{"last_name":"Tkačik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455","full_name":"Tkačik, Gašper","first_name":"Gašper"}],"ddc":["570"],"oa":1,"department":[{"_id":"GaTk"},{"_id":"NiBa"}],"researchdata_availability":"no","date_updated":"2026-08-12T09:56:02Z","language":[{"iso":"eng"}],"quality_controlled":"1","month":"06","publication_identifier":{"issn":["0959-437X"],"eissn":["1879-0380"]},"has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","dataavailabilitystatement":"No data were used for the research described in the article.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","project":[{"_id":"bd6958e0-d553-11ed-ba76-86eba6a76c00","name":"Understanding the evolution of continuous genomes","grant_number":"101055327"}],"supplementarymaterial":"no","abstract":[{"text":"Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences that bind transcription factor (TF) proteins to up- or down-regulate target genes. Decades-long efforts yielded TF-DNA interaction models that predict how strongly an individual TF binds arbitrary DNA sequences and how individual binding events on the CRE combine to affect gene expression. These insights can be synthesized into a global, biophysically realistic, and quantitative genotype-phenotype (GP) map for gene regulation, a ‘holy grail’ for the application of evolutionary theory. A global map provides a rare opportunity to simulate the long-term evolution of regulatory sequences and pose several fundamental questions: How long does it take to evolve CREs de novo? How many non-trivial regulatory functions exist in sequence space? How connected are they? For which regulatory architecture is CRE evolution most rapid and evolvable? In this article, the second of a two-part series, we review the application of evolutionary concepts — epistasis, robustness, evolvability, tunability, plasticity, and bet-hedging — to the evolution of gene regulatory sequences. We then evaluate the potential for a unifying theory for the evolution of regulatory sequences and identify key open challenges.","lang":"eng"}],"PlanS_conform":"1","oa_version":"Published Version","das_tickbox":"1","day":"01","doi":"10.1016/j.gde.2026.102472","file_date_updated":"2026-07-27T13:39:59Z","volume":98,"publication":"Current Opinion in Genetics & Development","OA_place":"publisher","title":"Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges","scopus_import":"1","OA_type":"hybrid","status":"public","type":"journal_article","date_published":"2026-06-01T00:00:00Z","acknowledgement":"We thank Calin Guet and Santiago Herrera-Álvarez for essential contributions to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship, jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science and Technology Austria (ISTA). N.B. acknowledges funding from the ERC Advanced Grant 101055327 “HaplotypeStructure”.\r\nThis study was also supported by the European Molecular Biology Laboratory (N.O.B., J.C.).","year":"2026","file":[{"creator":"dernst","date_updated":"2026-07-27T13:39:59Z","file_id":"22590","file_name":"2026_CurrentOpinionGeneticsDev_Mascolo.pdf","checksum":"ac8bbee61717bfe7116e312cc6825259","file_size":3190001,"access_level":"open_access","success":1,"relation":"main_file","content_type":"application/pdf","date_created":"2026-07-27T13:39:59Z"}],"article_number":"102472","_id":"21759"},{"date_created":"2026-01-25T23:01:39Z","publisher":"Company of Biologists","article_type":"original","intvolume":"       153","external_id":{"pmid":["41392708"]},"citation":{"ieee":"Q. Qian <i>et al.</i>, “Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut,” <i>Development</i>, vol. 153, no. 2. Company of Biologists, 2026.","ista":"Qian Q, NAGAI H, Sanaki Y, Hayashi M, Kimura K, Nakajima YI, Niwa R. 2026. Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. Development. 153(2), dev205225.","ama":"Qian Q, NAGAI H, Sanaki Y, et al. Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. <i>Development</i>. 2026;153(2). doi:<a href=\"https://doi.org/10.1242/dev.205225\">10.1242/dev.205225</a>","apa":"Qian, Q., NAGAI, H., Sanaki, Y., Hayashi, M., Kimura, K., Nakajima, Y. I., &#38; Niwa, R. (2026). Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. <i>Development</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/dev.205225\">https://doi.org/10.1242/dev.205225</a>","chicago":"Qian, Qingyin, HIROKI NAGAI, Yuya Sanaki, Makoto Hayashi, Kenichi Kimura, Yu Ichiro Nakajima, and Ryusuke Niwa. “Xrp1 Drives Damage-Induced Cellular Plasticity of Enteroendocrine Cells in the Adult Drosophila Midgut.” <i>Development</i>. Company of Biologists, 2026. <a href=\"https://doi.org/10.1242/dev.205225\">https://doi.org/10.1242/dev.205225</a>.","short":"Q. Qian, H. NAGAI, Y. Sanaki, M. Hayashi, K. Kimura, Y.I. Nakajima, R. Niwa, Development 153 (2026).","mla":"Qian, Qingyin, et al. “Xrp1 Drives Damage-Induced Cellular Plasticity of Enteroendocrine Cells in the Adult Drosophila Midgut.” <i>Development</i>, vol. 153, no. 2, dev205225, Company of Biologists, 2026, doi:<a href=\"https://doi.org/10.1242/dev.205225\">10.1242/dev.205225</a>."},"fulldoi":"https://doi.org/10.1242/dev.205225","oa":1,"author":[{"last_name":"Qian","full_name":"Qian, Qingyin","first_name":"Qingyin"},{"id":"608df3e6-e2ab-11ed-8890-c9318cec7da4","first_name":"Hiroki","full_name":"Nagai, Hiroki","orcid":"0000-0003-1671-9434","last_name":"Nagai"},{"last_name":"Sanaki","full_name":"Sanaki, Yuya","first_name":"Yuya"},{"last_name":"Hayashi","first_name":"Makoto","full_name":"Hayashi, Makoto"},{"first_name":"Kenichi","full_name":"Kimura, Kenichi","last_name":"Kimura"},{"first_name":"Yu Ichiro","full_name":"Nakajima, Yu Ichiro","last_name":"Nakajima"},{"full_name":"Niwa, Ryusuke","first_name":"Ryusuke","last_name":"Niwa"}],"language":[{"iso":"eng"}],"date_updated":"2026-08-12T10:01:56Z","department":[{"_id":"XiFe"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","pmid":1,"month":"01","quality_controlled":"1","article_processing_charge":"No","publication_identifier":{"eissn":["1477-9129"],"issn":["0950-1991"]},"day":"15","doi":"10.1242/dev.205225","issue":"2","volume":153,"publication":"Development","abstract":[{"text":"Cellular plasticity, the ability of a differentiated cell to adopt another phenotypic identity, is restricted under basal conditions, but can be elicited upon damage. However, the molecular mechanism enabling such plasticity remains largely unexplored. Here, we report damage-induced cellular plasticity of secretory enteroendocrine cells (EEs) in the adult Drosophila midgut. Ionizing radiation induces EE fate conversion and activates stress-responsive programs in EE lineages, accompanied by the induction of the stress-inducible transcription factor Xrp1 and the cytokine gene upd3. Xrp1 and upd3 are both necessary for radiation-induced EE plasticity. Under basal conditions, EE-specific Xrp1 overexpression triggers ectopic expression of progenitor-specific genes, which is necessary for Xrp1 to drive EE plasticity. Our work identifies Xrp1 as a crucial regulator that coordinates damage-induced signaling and transcriptional reprogramming, enabling the reactivation of cellular plasticity in differentiated cells.","lang":"eng"}],"oa_version":"Preprint","OA_type":"green","title":"Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut","OA_place":"repository","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.07.05.662934"}],"article_number":"dev205225","_id":"21039","year":"2026","type":"journal_article","status":"public","acknowledgement":"We thank Pierre Léopold, Tatsushi Igaki, Erik Storkebaum, Tobias Reiff, Masayuki Miura, Xiaohang Yang, Mikio Furuse, Bloomington Drosophila Stock Center and Developmental Studies Hybridoma Bank for providing us with fly stocks and reagents. We are also grateful to Hiromi Yanagisawa, Satoru Kobayashi, Md Al Amin Sheikh and Yaxuan Cui for allowing us to use their equipment, and to Allison Bardin, Pierre Léopold and Tadashi Uemura for helpful discussions.","date_published":"2026-01-15T00:00:00Z"},{"page":"215-236","external_id":{"arxiv":["2603.07094"]},"citation":{"mla":"Brice, Leonard J., et al. “Randomise Alone, Reach as a Team.” <i>38th International Conference on Computer Aided Verification</i>, vol. 16682, Springer Nature, 2026, pp. 215–36, doi:<a href=\"https://doi.org/10.1007/978-3-032-32519-8_12\">10.1007/978-3-032-32519-8_12</a>.","short":"L.J. Brice, T.A. Henzinger, A. Montaseri, A. Shafiee, K.S. Thejaswini, in:, 38th International Conference on Computer Aided Verification, Springer Nature, 2026, pp. 215–236.","chicago":"Brice, Leonard J, Thomas A Henzinger, Alipasha Montaseri, Ali Shafiee, and K. S. Thejaswini. “Randomise Alone, Reach as a Team.” In <i>38th International Conference on Computer Aided Verification</i>, 16682:215–36. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-32519-8_12\">https://doi.org/10.1007/978-3-032-32519-8_12</a>.","apa":"Brice, L. J., Henzinger, T. A., Montaseri, A., Shafiee, A., &#38; Thejaswini, K. S. (2026). Randomise alone, reach as a team. In <i>38th International Conference on Computer Aided Verification</i> (Vol. 16682, pp. 215–236). Lisbon, Portugal: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-32519-8_12\">https://doi.org/10.1007/978-3-032-32519-8_12</a>","ama":"Brice LJ, Henzinger TA, Montaseri A, Shafiee A, Thejaswini KS. Randomise alone, reach as a team. In: <i>38th International Conference on Computer Aided Verification</i>. Vol 16682. Springer Nature; 2026:215-236. doi:<a href=\"https://doi.org/10.1007/978-3-032-32519-8_12\">10.1007/978-3-032-32519-8_12</a>","ista":"Brice LJ, Henzinger TA, Montaseri A, Shafiee A, Thejaswini KS. 2026. Randomise alone, reach as a team. 38th International Conference on Computer Aided Verification. CAV: Computer Aided Verification vol. 16682, 215–236.","ieee":"L. J. Brice, T. A. Henzinger, A. Montaseri, A. Shafiee, and K. S. Thejaswini, “Randomise alone, reach as a team,” in <i>38th International Conference on Computer Aided Verification</i>, Lisbon, Portugal, 2026, vol. 16682, pp. 215–236."},"fulldoi":"https://doi.org/10.1007/978-3-032-32519-8_12","intvolume":"     16682","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_created":"2026-08-16T22:01:44Z","publisher":"Springer Nature","language":[{"iso":"eng"}],"date_updated":"2026-08-18T06:55:38Z","department":[{"_id":"ToHe"},{"_id":"GradSch"}],"researchdata_availability":"yes","author":[{"last_name":"Brice","id":"ce3b3409-db6c-11f0-aa64-ad678f7fd937","first_name":"Leonard J","full_name":"Brice, Leonard J"},{"last_name":"Henzinger","orcid":"0000-0002-2985-7724","full_name":"Henzinger, Thomas A","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Montaseri","full_name":"Montaseri, Alipasha","first_name":"Alipasha","id":"709a7f96-8896-11f0-9809-d75612fc0f2e"},{"last_name":"Shafiee","first_name":"Ali","full_name":"Shafiee, Ali","id":"2783031a-7378-11f0-b2d0-f17f1db2ebad"},{"last_name":"Thejaswini","first_name":"K. S.","full_name":"Thejaswini, K. S."}],"ddc":["000"],"ec_funded":1,"oa":1,"arxiv":1,"abstract":[{"text":"We study concurrent graph games where n players cooperate against an opponent to reach a set of target states. Unlike traditional settings, we study distributed randomisation: team players do not share a source of randomness, and their private random sources are hidden from the opponent and from each other.\r\n\r\nWe show that memoryless strategies are sufficient for the threshold problem (deciding whether there is a strategy for the team that ensures winning with probability that exceeds a threshold), a result that not only places the problem in the Existential Theory of the Reals (ER) but also enables the construction of value iteration algorithms. We additionally show that the threshold problem is NP-hard. For the almost-sure reachability problem, we prove NP-completeness.\r\n\r\nWe introduce Individually Randomised Alternating-time Temporal Logic (IRATL). This logic extends the standard ATL framework to reason about probability thresholds, with semantics explicitly designed for coalitions that lack a shared source of randomness. On the practical side, we implement and evaluate a solver for the threshold and almost-sure problem based on the algorithms that we develop.","lang":"eng"}],"das_tickbox":"1","oa_version":"Published Version","day":"24","doi":"10.1007/978-3-032-32519-8_12","volume":16682,"file_date_updated":"2026-08-18T06:53:22Z","publication":"38th International Conference on Computer Aided Verification","month":"07","quality_controlled":"1","article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783032325181"],"issn":["0302-9743"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"The artifact can be accessed at the link: https://doi. org/10.5281/zenodo.19680359.\r\nThe source code is available at:https://github.com/alipashamontaseri/Team-Concurrent-Game.","supplementarymaterial":"no","publication_status":"published","project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","grant_number":"101020093"}],"type":"conference","status":"public","date_published":"2026-07-24T00:00:00Z","acknowledgement":"This work is a part of project VAMOS that has received funding from the European Research Council (ERC), grant agreement No 101020093. Part of this work was realised when the first author was an FNRS aspirant at Université libre de Bruxelles.","conference":{"location":"Lisbon, Portugal","name":"CAV: Computer Aided Verification","end_date":"2026-07-29","start_date":"2026-07-26"},"_id":"22717","year":"2026","file":[{"date_created":"2026-08-18T06:53:22Z","content_type":"application/pdf","success":1,"relation":"main_file","file_size":1902192,"file_name":"2026_LNCS_Brice.pdf","date_updated":"2026-08-18T06:53:22Z","checksum":"10ded8a3ab9ed34c9e4794c0b277622c","file_id":"22724","access_level":"open_access","creator":"dernst"}],"title":"Randomise alone, reach as a team","OA_place":"publisher","scopus_import":"1","OA_type":"hybrid"},{"oa":1,"arxiv":1,"author":[{"first_name":"Meital I","full_name":"Bojan, Meital I","id":"11d88cf5-91ca-11f0-a95f-edf9f08f47b7","last_name":"Bojan"},{"last_name":"Vedula","first_name":"Sanketh","full_name":"Vedula, Sanketh"},{"last_name":"Maddipatla","id":"e957f5e5-91c9-11f0-a95f-e090f66ecb4d","full_name":"Maddipatla, Sai A","first_name":"Sai A"},{"full_name":"Sellam, Nadav E","first_name":"Nadav E","id":"ef280fe0-91c9-11f0-a95f-8dea3f5bc513","last_name":"Sellam"},{"full_name":"Rzayev, Anar","first_name":"Anar","id":"2cd60677-9acd-11f1-ae1a-a85ae1c4dd35","last_name":"Rzayev"},{"orcid":"0000-0002-9043-136X","first_name":"Federico","full_name":"Napoli, Federico","id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","last_name":"Napoli"},{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","first_name":"Paul","full_name":"Schanda, Paul","orcid":"0000-0002-9350-7606","last_name":"Schanda"},{"last_name":"Bronstein","id":"58f3726e-7cba-11ef-ad8b-e6e8cb3904e6","first_name":"Alexander","full_name":"Bronstein, Alexander","orcid":"0000-0001-9699-8730"}],"ddc":["000","570"],"department":[{"_id":"GradSch"},{"_id":"PaSc"},{"_id":"AlBr"}],"date_updated":"2026-08-18T06:36:55Z","language":[{"iso":"eng"}],"researchdata_availability":"yes","date_created":"2026-08-17T12:03:24Z","acknowledged_ssus":[{"_id":"ScienComp"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"      2026","page":"100760-100799","external_id":{"arxiv":["2505.23354"]},"corr_author":"1","citation":{"ieee":"M. I. Bojan <i>et al.</i>, “Representing local protein environments with machine learning force fields,” in <i>14th International Conference on Learning Representations</i>, Rio de Janeiro, Brazil, 2026, vol. 2026, pp. 100760–100799.","ista":"Bojan MI, Vedula S, Maddipatla SA, Sellam NE, Rzayev A, Napoli F, Schanda P, Bronstein AM. 2026. Representing local protein environments with machine learning force fields. 14th International Conference on Learning Representations. ICLR: International Conference on Learning Representations vol. 2026, 100760–100799.","ama":"Bojan MI, Vedula S, Maddipatla SA, et al. Representing local protein environments with machine learning force fields. In: <i>14th International Conference on Learning Representations</i>. Vol 2026. ; 2026:100760-100799.","apa":"Bojan, M. I., Vedula, S., Maddipatla, S. A., Sellam, N. E., Rzayev, A., Napoli, F., … Bronstein, A. M. (2026). Representing local protein environments with machine learning force fields. In <i>14th International Conference on Learning Representations</i> (Vol. 2026, pp. 100760–100799). Rio de Janeiro, Brazil.","chicago":"Bojan, Meital I, Sanketh Vedula, Sai A Maddipatla, Nadav E Sellam, Anar Rzayev, Federico Napoli, Paul Schanda, and Alex M. Bronstein. “Representing Local Protein Environments with Machine Learning Force Fields.” In <i>14th International Conference on Learning Representations</i>, 2026:100760–99, 2026.","short":"M.I. Bojan, S. Vedula, S.A. Maddipatla, N.E. Sellam, A. Rzayev, F. Napoli, P. Schanda, A.M. Bronstein, in:, 14th International Conference on Learning Representations, 2026, pp. 100760–100799.","mla":"Bojan, Meital I., et al. “Representing Local Protein Environments with Machine Learning Force Fields.” <i>14th International Conference on Learning Representations</i>, vol. 2026, 2026, pp. 100760–99."},"OA_type":"gold","title":"Representing local protein environments with machine learning force fields","OA_place":"publisher","_id":"22722","file":[{"access_level":"open_access","file_name":"2026_ICLR_Bojan.pdf","date_updated":"2026-08-18T06:33:14Z","file_id":"22723","checksum":"9f43f5469443388ec55388d95c4cf243","file_size":8534339,"creator":"dernst","content_type":"application/pdf","date_created":"2026-08-18T06:33:14Z","relation":"main_file","success":1}],"year":"2026","type":"conference","related_material":{"link":[{"url":"https://github.com/mb012/MLFF_representation","relation":"software"}]},"status":"public","date_published":"2026-05-01T00:00:00Z","acknowledgement":"This work was supported by the Institute of Science and Technology Austria (ISTA) through the IPC\r\ngrant “Generative Protein NMR” and by the Israeli Science Foundation (ISF) under grant number\r\n1834/24. This research used resources of the Institute of Science and Technology Austria’s scientific\r\ncomputing cluster. S.V. was supported in part by funding from the Eric and Wendy Schmidt Center at\r\nthe Broad Institute of MIT and Harvard.","conference":{"start_date":"2026-04-23","name":"ICLR: International Conference on Learning Representations","location":"Rio de Janeiro, Brazil","end_date":"2026-04-27"},"dataavailabilitystatement":"The code, trained models, and data-processing scripts are publicly available at https://github.\r\ncom/mb012/MLFF_representation. In addition, complete details of the models and optimization parameters are provided in Appendix G.3. The hardware resources used to produce the\r\nresults are specified in Appendix I.4. The loss functions, evaluation metrics, and details regarding\r\nablation studies are specified in Appendix G. These details ensure that all results reported in the paper\r\ncan be independently verified.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","publication_status":"published","month":"05","quality_controlled":"1","article_processing_charge":"No","has_accepted_license":"1","day":"01","file_date_updated":"2026-08-18T06:33:14Z","volume":2026,"publication":"14th International Conference on Learning Representations","abstract":[{"lang":"eng","text":"The local structure of a protein strongly impacts its function and interactions\r\nwith other molecules. Representing local biomolecular environments remains a\r\nkey challenge while applying machine learning approaches over protein structures. The structural and chemical variability of these environments makes them\r\nchallenging to model, and performing representation learning on these objects\r\nremains largely under-explored. In this work, we propose representations for\r\nlocal protein environments that leverage intermediate features from machine learning force fields (MLFFs). We extensively benchmark state-of-the-art MLFFs,\r\ncomparing their performance across latent spaces and downstream tasks, and\r\nshow that their embeddings capture local structural (e.g., secondary motifs) and\r\nchemical features (e.g., amino acid identity and protonation state), organizing\r\nprotein environments into a structured manifold. We show that these representations enable zero-shot generalization and transfer across diverse downstream\r\ntasks. As a case study, we build a physics-informed, uncertainty-aware chemical shift predictor that achieves state-of-the-art accuracy in biomolecular NMR\r\nspectroscopy. Our results establish MLFFs as general-purpose, reusable representation learners for protein modeling, opening new directions in representation learning for structured physical systems. Code and data are available at\r\nhttps://github.com/mb012/MLFF_representation.\r\n"}],"das_tickbox":"1","oa_version":"Published Version"},{"doi":"10.1007/978-3-032-32519-8_13","day":"24","file_date_updated":"2026-08-18T08:40:07Z","publication":"38th International Conference on Computer Aided Verification","volume":16682,"abstract":[{"text":"We study the problem of generating paths on a graph that satisfy a collection of w-regular objectives. We propose a decoupled framework in which each objective is assigned to an independent agent that selects a local policy, while a scheduler—oblivious to the graph and objective—dynamically composes these policies into a single path. We ask when such a composition satisfies all objectives, assuming their conjunction is realizable. The framework enables modular policy design but raises fundamental compositional challenges. We show that even extremely fair deterministic schedulers do not ensure correctness, and that stochastic schedulers, while necessary, are insufficient without coordination. For safety objectives, we demonstrate that fully decentralized implementations are impossible, and we introduce a protocol for synchronizing on maximal safe actions. For non-safety objectives, we introduce conventions—simple, a priori restrictions agreed upon before the graph or objectives are revealed—that guarantee satisfaction of all objectives when followed by all agents. We characterize minimally restrictive conventions for major subclasses of w-regular objectives. In particular, Büchi objectives admit universal composition of finite-memory policies without scheduler communication; co-Büchi objectives require only knowledge of whether the agent was scheduled; and parity objectives additionally require knowledge of which agent was scheduled.","lang":"eng"}],"oa_version":"Published Version","das_tickbox":"0","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software"}],"publication_status":"published","supplementarymaterial":"no","quality_controlled":"1","month":"07","publication_identifier":{"isbn":["9783032325181"],"issn":["0302-9743"],"eissn":["1611-3349"]},"article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","file":[{"creator":"dernst","date_updated":"2026-08-18T08:40:07Z","checksum":"f17ba3f82854fdb4eb69fd922965661a","file_name":"2026_LNCS_Avni.pdf","file_id":"22730","file_size":531980,"access_level":"open_access","success":1,"relation":"main_file","content_type":"application/pdf","date_created":"2026-08-18T08:40:07Z"}],"year":"2026","_id":"22719","status":"public","type":"conference","conference":{"start_date":"2026-07-26","name":"CAV: Computer Aided Verification","location":"Lisbon, Portugal","end_date":"2026-07-29"},"date_published":"2026-07-24T00:00:00Z","acknowledgement":"This work is funded by the following grants: European Research Council under Grant No.: ERC-2020-AdG 101020093, ISF grant no. 1679/21, grant RYC2024-049116, MICIU/AEI/10.13039/501100011033, the ESF+, and Volkswagen Foundation within its Momentum framework under project no. 9C283.","OA_type":"hybrid","OA_place":"publisher","title":"Decoupled planning for multiple omega-regular objectives","scopus_import":"1","intvolume":"     16682","page":"237-257","external_id":{"arxiv":["2605.13185"]},"fulldoi":"https://doi.org/10.1007/978-3-032-32519-8_13","citation":{"ieee":"G. Avni, T. A. Henzinger, K. Mallik, S. Sadhukhan, and K. S. Thejaswini, “Decoupled planning for multiple omega-regular objectives,” in <i>38th International Conference on Computer Aided Verification</i>, Lisbon, Portugal, 2026, vol. 16682, pp. 237–257.","ista":"Avni G, Henzinger TA, Mallik K, Sadhukhan S, Thejaswini KS. 2026. Decoupled planning for multiple omega-regular objectives. 38th International Conference on Computer Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 16682, 237–257.","apa":"Avni, G., Henzinger, T. A., Mallik, K., Sadhukhan, S., &#38; Thejaswini, K. S. (2026). Decoupled planning for multiple omega-regular objectives. In <i>38th International Conference on Computer Aided Verification</i> (Vol. 16682, pp. 237–257). Lisbon, Portugal: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-32519-8_13\">https://doi.org/10.1007/978-3-032-32519-8_13</a>","ama":"Avni G, Henzinger TA, Mallik K, Sadhukhan S, Thejaswini KS. Decoupled planning for multiple omega-regular objectives. In: <i>38th International Conference on Computer Aided Verification</i>. Vol 16682. Springer Nature; 2026:237-257. doi:<a href=\"https://doi.org/10.1007/978-3-032-32519-8_13\">10.1007/978-3-032-32519-8_13</a>","chicago":"Avni, Guy, Thomas A Henzinger, Kaushik Mallik, Suman Sadhukhan, and K. S. Thejaswini. “Decoupled Planning for Multiple Omega-Regular Objectives.” In <i>38th International Conference on Computer Aided Verification</i>, 16682:237–57. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-32519-8_13\">https://doi.org/10.1007/978-3-032-32519-8_13</a>.","short":"G. Avni, T.A. Henzinger, K. Mallik, S. Sadhukhan, K.S. Thejaswini, in:, 38th International Conference on Computer Aided Verification, Springer Nature, 2026, pp. 237–257.","mla":"Avni, Guy, et al. “Decoupled Planning for Multiple Omega-Regular Objectives.” <i>38th International Conference on Computer Aided Verification</i>, vol. 16682, Springer Nature, 2026, pp. 237–57, doi:<a href=\"https://doi.org/10.1007/978-3-032-32519-8_13\">10.1007/978-3-032-32519-8_13</a>."},"date_created":"2026-08-16T22:01:44Z","publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"alternative_title":["LNCS"],"language":[{"iso":"eng"}],"date_updated":"2026-08-18T08:41:44Z","researchdata_availability":"no","department":[{"_id":"ToHe"}],"ec_funded":1,"arxiv":1,"oa":1,"author":[{"last_name":"Avni","full_name":"Avni, Guy","first_name":"Guy","orcid":"0000-0001-5588-8287","id":"463C8BC2-F248-11E8-B48F-1D18A9856A87"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","full_name":"Henzinger, Thomas A","orcid":"0000-0002-2985-7724","last_name":"Henzinger"},{"id":"0834ff3c-6d72-11ec-94e0-b5b0a4fb8598","orcid":"0000-0001-9864-7475","full_name":"Mallik, Kaushik","first_name":"Kaushik","last_name":"Mallik"},{"last_name":"Sadhukhan","full_name":"Sadhukhan, Suman","first_name":"Suman"},{"last_name":"Thejaswini","first_name":"K. S.","full_name":"Thejaswini, K. S."}],"ddc":["000"]},{"publication_status":"published","supplementarymaterial":"no","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["000-4637X"],"eissn":["1538-4357"]},"has_accepted_license":"1","article_processing_charge":"Yes","quality_controlled":"1","month":"08","publication":"The Astrophysical Journal","volume":1007,"file_date_updated":"2026-08-18T09:01:50Z","issue":"1","doi":"10.3847/1538-4357/ae8760","day":"10","PlanS_conform":"1","oa_version":"Published Version","das_tickbox":"0","abstract":[{"text":"Ground-based gravitational-wave (GW) observatories have detected approximately 200 binary black hole (BH) mergers. The astrophysical origin of these events is debated, with evidence suggesting that at least a subset originated from dynamic environments characterized by frequent close encounters. Accretion disks in active galactic nuclei (AGNs) are of particular interest, as certain observed features could be more readily produced within such environments. In this paper, we investigate the expected properties of mergers in these environments, and their dependence on various parameters, using 1D N-body simulations combined with a comprehensive semianalytical model. In our fiducial model, the distributions of masses (m1 and m2) and mass ratios (q ≡ m2/m1 ≤ 1) are similar to those observed. However, they depend strongly on the lifetime and density of the AGN disk and on the number and accretion efficiency of BHs, with higher masses predicted as these quantities increase. The most massive mergers, such as GW231123, can be produced either by efficient gas accretion or by hierarchical mergers among ≥3 generations of BHs. The observed negative correlation between q and the average effective spin (χeff), along with the positive correlation between χeff and the chirp mass (Mchirp), can be explained by a combination of efficient gas accretion, which promotes spin alignment, and hierarchical mergers, which produce high-∣χeff∣ and low-q binaries. Hierarchical mergers can also explain the negative correlation between q and the dispersion of χeff, as well as the positive correlation between ∣χeff∣and Mchirp. We present a comprehensive study on how the expected distribution of each of these quantities depends on model parameters and assumptions, which will aid the interpretation of observed GW population properties.","lang":"eng"}],"OA_type":"gold","scopus_import":"1","OA_place":"publisher","title":"Properties of black hole mergers in disks of active galactic nuclei","file":[{"creator":"dernst","date_updated":"2026-08-18T09:01:50Z","checksum":"1531fd5997b054d26e99d44ccc7f8ff5","file_id":"22731","file_name":"2026_AstrophysicalJour_Tagawa.pdf","file_size":2246236,"access_level":"open_access","success":1,"relation":"main_file","content_type":"application/pdf","date_created":"2026-08-18T09:01:50Z"}],"year":"2026","article_number":"67","_id":"22713","date_published":"2026-08-10T00:00:00Z","acknowledgement":"H.T. is supported by the National Science and Technology Major Project of China (No. 2024ZD1100601) and the National Key R&D Program of China (grant No.2024YFC2207700). Z.H. was supported by NASA grants 80NSSC22K0822 and 80NSSC24K0440. B.K. is supported by the Science and Technology Facilities Council grant No. ST/W000903/1. Simulations were carried out on Cray XD2000 at the Center for Computational Astrophysics, National Astronomical Observatory of Japan.","status":"public","type":"journal_article","publisher":"IOP Publishing","DOAJ_listed":"1","date_created":"2026-08-16T22:01:43Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"      1007","article_type":"original","fulldoi":"https://doi.org/10.3847/1538-4357/ae8760","citation":{"mla":"Tagawa, Hiromichi, et al. “Properties of Black Hole Mergers in Disks of Active Galactic Nuclei.” <i>The Astrophysical Journal</i>, vol. 1007, no. 1, 67, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae8760\">10.3847/1538-4357/ae8760</a>.","chicago":"Tagawa, Hiromichi, Zoltán Haiman, and Bence Kocsis. “Properties of Black Hole Mergers in Disks of Active Galactic Nuclei.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae8760\">https://doi.org/10.3847/1538-4357/ae8760</a>.","short":"H. Tagawa, Z. Haiman, B. Kocsis, The Astrophysical Journal 1007 (2026).","ama":"Tagawa H, Haiman Z, Kocsis B. Properties of black hole mergers in disks of active galactic nuclei. <i>The Astrophysical Journal</i>. 2026;1007(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae8760\">10.3847/1538-4357/ae8760</a>","apa":"Tagawa, H., Haiman, Z., &#38; Kocsis, B. (2026). Properties of black hole mergers in disks of active galactic nuclei. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae8760\">https://doi.org/10.3847/1538-4357/ae8760</a>","ista":"Tagawa H, Haiman Z, Kocsis B. 2026. Properties of black hole mergers in disks of active galactic nuclei. The Astrophysical Journal. 1007(1), 67.","ieee":"H. Tagawa, Z. Haiman, and B. Kocsis, “Properties of black hole mergers in disks of active galactic nuclei,” <i>The Astrophysical Journal</i>, vol. 1007, no. 1. IOP Publishing, 2026."},"external_id":{"arxiv":["2604.25994"]},"arxiv":1,"oa":1,"ddc":["520"],"author":[{"last_name":"Tagawa","first_name":"Hiromichi","full_name":"Tagawa, Hiromichi"},{"id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","orcid":"0000-0003-3633-5403","full_name":"Haiman, Zoltán","first_name":"Zoltán","last_name":"Haiman"},{"last_name":"Kocsis","first_name":"Bence","full_name":"Kocsis, Bence"}],"department":[{"_id":"ZoHa"}],"language":[{"iso":"eng"}],"researchdata_availability":"no","date_updated":"2026-08-18T09:05:25Z"},{"scopus_import":"1","title":"CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators","OA_place":"publisher","OA_type":"hybrid","date_published":"2026-08-06T00:00:00Z","acknowledgement":"We thank all members of the Robles’ group for critical comments on and edits to this paper. We thank S. Kay for providing dihXY HCC cell lines and D. Firsov and Y. Bignon for mouse BMAL1-knockout (KO) kidney tissues. This work was supported by the German Research Foundation (DFG) project no. 213249687—SFB 1064 and RO 5675/1-1 to M.S.R., F.A. and L.A.H. M.S.R was also supported by DFG INST 86/1800-1 FUGG and LMU Munich’s Institutional Strategy LMU excellent within the framework of the German Excellence Initiative. J.S.M. was supported by US National Institutes of Health grant nos. R01GM145737 and R01DK128133. A.K.M. was supported by an ERC grant ‘ChromaChrono’ 101162145. Open access funding provided by Ludwig-Maximilians-Universität München.","type":"journal_article","status":"public","_id":"22720","year":"2026","main_file_link":[{"url":"https://doi.org/10.1038/s41556-026-02041-4","open_access":"1"}],"article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","publication_identifier":{"eissn":["1476-4679"],"issn":["1465-7392"]},"month":"08","quality_controlled":"1","supplementarymaterial":"yes","project":[{"_id":"9136c684-16d5-11f0-9cad-91c0177b365f","name":"Circadian structural transitions of chromatin","grant_number":"101162145"}],"publication_status":"epub_ahead","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"Proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE64 partner repository with the dataset identifiers PXD062751 and PXD077567. RNA-seq data are available in the European Nucleotide Archive (ENA) under accession no. PRJEB93884, and ChIP–seq data at the Gene Expression Omnibus (GEO) under accession no. GSE302237. AlphaFold 3 interaction prediction parameters can be provided during the revision process on editorial and/or review request. Source data are provided with this paper.","das_tickbox":"1","PlanS_conform":"1","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Circadian clocks underlie daily rhythms in physiology by coordinating temporal patterns of gene expression and protein function throughout the body. At the core of this system in mammals is CLOCK/BMAL1, a ubiquitously expressed heterodimeric transcription factor complex that orchestrates tissue-specific circadian gene expression. The basis for this specificity remains unclear, but tissue-specific interactions at chromatin could provide one. Here we used chromatin immunoprecipitation coupled to mass spectrometry to map CLOCK/BMAL1-associated protein complexes on chromatin in mouse liver, kidney and lung. We detected 1,510 associated proteins, most of which were tissue-specific and not explained by protein abundance. Among these, we identified the homeodomain transcription factors PROX1, HNF1B and HOXA5 as tissue-enriched interactors that bind BMAL1, co-occupy most BMAL1 genomic sites and establish organ-restricted circadian transcription. Our findings demonstrate that tissue-specific transcription factors confer cellular identity on the core clock, thereby contributing to organ-specific patterns of rhythmic gene expression."}],"publication":"Nature Cell Biology","day":"06","doi":"10.1038/s41556-026-02041-4","ddc":["570"],"author":[{"last_name":"Aygenli","full_name":"Aygenli, Fatih","first_name":"Fatih"},{"full_name":"Huschet, Lukas A.","first_name":"Lukas A.","last_name":"Huschet"},{"first_name":"Tanja","full_name":"Popp, Tanja","last_name":"Popp"},{"last_name":"Ribeiro","first_name":"Andrea","full_name":"Ribeiro, Andrea"},{"last_name":"Barkhatova","id":"db547c8c-329f-11ee-a353-cde802618f9e","orcid":"0000-0002-0062-2817","full_name":"Barkhatova, Darina","first_name":"Darina"},{"last_name":"Jouffe","first_name":"Céline","full_name":"Jouffe, Céline"},{"first_name":"Ricardo","full_name":"Trozzo, Ricardo","last_name":"Trozzo"},{"last_name":"Menet","full_name":"Menet, Jerome S.","first_name":"Jerome S."},{"full_name":"Rad, Roland","first_name":"Roland","last_name":"Rad"},{"full_name":"Dyar, Kenneth A.","first_name":"Kenneth A.","last_name":"Dyar"},{"last_name":"Lech","first_name":"Maciej","full_name":"Lech, Maciej"},{"last_name":"Straub","first_name":"Tobias","full_name":"Straub, Tobias"},{"orcid":"0000-0002-6080-839X","full_name":"Michael, Alicia","first_name":"Alicia","id":"6437c950-2a03-11ee-914d-d6476dd7b75c","last_name":"Michael"},{"full_name":"Robles, Maria S.","first_name":"Maria S.","last_name":"Robles"}],"oa":1,"date_updated":"2026-08-18T08:03:22Z","department":[{"_id":"GradSch"},{"_id":"AlMi"}],"researchdata_availability":"yes","language":[{"iso":"eng"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publisher":"Springer Nature","date_created":"2026-08-16T22:01:44Z","citation":{"ista":"Aygenli F, Huschet LA, Popp T, Ribeiro A, Barkhatova D, Jouffe C, Trozzo R, Menet JS, Rad R, Dyar KA, Lech M, Straub T, Michael AK, Robles MS. 2026. CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators. Nature Cell Biology.","ieee":"F. Aygenli <i>et al.</i>, “CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators,” <i>Nature Cell Biology</i>. Springer Nature, 2026.","apa":"Aygenli, F., Huschet, L. A., Popp, T., Ribeiro, A., Barkhatova, D., Jouffe, C., … Robles, M. S. (2026). CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators. <i>Nature Cell Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41556-026-02041-4\">https://doi.org/10.1038/s41556-026-02041-4</a>","ama":"Aygenli F, Huschet LA, Popp T, et al. CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators. <i>Nature Cell Biology</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41556-026-02041-4\">10.1038/s41556-026-02041-4</a>","chicago":"Aygenli, Fatih, Lukas A. Huschet, Tanja Popp, Andrea Ribeiro, Darina Barkhatova, Céline Jouffe, Ricardo Trozzo, et al. “CLOCK/BMAL1 Interactome Uncovers Homeodomain Factors as Tissue Regulators.” <i>Nature Cell Biology</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41556-026-02041-4\">https://doi.org/10.1038/s41556-026-02041-4</a>.","short":"F. Aygenli, L.A. Huschet, T. Popp, A. Ribeiro, D. Barkhatova, C. Jouffe, R. Trozzo, J.S. Menet, R. Rad, K.A. Dyar, M. Lech, T. Straub, A.K. Michael, M.S. Robles, Nature Cell Biology (2026).","mla":"Aygenli, Fatih, et al. “CLOCK/BMAL1 Interactome Uncovers Homeodomain Factors as Tissue Regulators.” <i>Nature Cell Biology</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41556-026-02041-4\">10.1038/s41556-026-02041-4</a>."},"fulldoi":"https://doi.org/10.1038/s41556-026-02041-4","external_id":{"pmid":["42562924"]},"article_type":"original"},{"mathsc":["65N30","76D07","76M10"],"publisher":"World Scientific Publishing","date_created":"2026-08-16T22:01:44Z","citation":{"chicago":"Gazca-Orozco, Pablo Alexei, Franz Gmeineder, Erika Maringová, and Tabea Tscherpel. “A Nitsche Method for Incompressible Fluids with General Dynamic Boundary Conditions.” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026. <a href=\"https://doi.org/10.1142/S0218202526500508\">https://doi.org/10.1142/S0218202526500508</a>.","short":"P.A. Gazca-Orozco, F. Gmeineder, E. Maringová, T. Tscherpel, Mathematical Models and Methods in Applied Sciences (2026).","mla":"Gazca-Orozco, Pablo Alexei, et al. “A Nitsche Method for Incompressible Fluids with General Dynamic Boundary Conditions.” <i>Mathematical Models and Methods in Applied Sciences</i>, World Scientific Publishing, 2026, doi:<a href=\"https://doi.org/10.1142/S0218202526500508\">10.1142/S0218202526500508</a>.","ista":"Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. 2026. A Nitsche method for incompressible fluids with general dynamic boundary conditions. Mathematical Models and Methods in Applied Sciences.","ieee":"P. A. Gazca-Orozco, F. Gmeineder, E. Maringová, and T. Tscherpel, “A Nitsche method for incompressible fluids with general dynamic boundary conditions,” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026.","ama":"Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. A Nitsche method for incompressible fluids with general dynamic boundary conditions. <i>Mathematical Models and Methods in Applied Sciences</i>. 2026. doi:<a href=\"https://doi.org/10.1142/S0218202526500508\">10.1142/S0218202526500508</a>","apa":"Gazca-Orozco, P. A., Gmeineder, F., Maringová, E., &#38; Tscherpel, T. (2026). A Nitsche method for incompressible fluids with general dynamic boundary conditions. <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0218202526500508\">https://doi.org/10.1142/S0218202526500508</a>"},"fulldoi":"https://doi.org/10.1142/S0218202526500508","external_id":{"arxiv":["2502.09550"]},"article_type":"original","author":[{"first_name":"Pablo Alexei","full_name":"Gazca-Orozco, Pablo Alexei","last_name":"Gazca-Orozco"},{"last_name":"Gmeineder","full_name":"Gmeineder, Franz","first_name":"Franz"},{"id":"dbabca31-66eb-11eb-963a-fb9c22c880b4","full_name":"Maringová, Erika","first_name":"Erika","last_name":"Maringová"},{"first_name":"Tabea","full_name":"Tscherpel, Tabea","last_name":"Tscherpel"}],"oa":1,"arxiv":1,"date_updated":"2026-08-18T07:51:59Z","language":[{"iso":"eng"}],"department":[{"_id":"JuFi"}],"article_processing_charge":"No","publication_identifier":{"issn":["0218-2025"],"eissn":["1793-6314"]},"month":"08","quality_controlled":"1","publication_status":"epub_ahead","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","abstract":[{"text":"Both Newtonian and non-Newtonian fluids may exhibit complex slip behaviour at the boundary. We examine a broad class of slip boundary conditions that generalises the commonly used Navier slip, perfect slip, stick-slip and Tresca friction boundary conditions. In particular, set-valued, nonmonotone, noncoercive and dynamic relations may occur. For a unifying framework of such relations, we present a fully discrete numerical scheme for the time-dependent Navier–Stokes equations subject to impermeability and general slip-type boundary conditions on polyhedral domains. Based on compactness arguments, we prove convergence of subsequences, finally ensuring the existence of a weak solution. The numerical scheme uses a general inf-sup stable pair of finite element spaces for the velocity and pressure, a regularisation approach for the implicit slip boundary condition and, most importantly, a general Nitsche method to impose the impermeability and a backward Euler time stepping. One of the key tools in the convergence proof is an inhomogeneous Korn inequality that includes a normal trace term.","lang":"eng"}],"publication":"Mathematical Models and Methods in Applied Sciences","day":"04","doi":"10.1142/S0218202526500508","scopus_import":"1","title":"A Nitsche method for incompressible fluids with general dynamic boundary conditions","OA_place":"repository","OA_type":"green","date_published":"2026-08-04T00:00:00Z","type":"journal_article","status":"public","_id":"22718","year":"2026","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2502.09550"}]},{"article_type":"letter_note","intvolume":"        11","corr_author":"1","page":"5752-5762","citation":{"apa":"Liu, Y., Kleinhanns, T., Spadaro, M. C., Genç, A., Horta, S., Jakhar, N., … Ibáñez, M. (2026). Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>","ama":"Liu Y, Kleinhanns T, Spadaro MC, et al. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. 2026;11(8):5752-5762. doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>","ieee":"Y. Liu <i>et al.</i>, “Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se,” <i>ACS Energy Letters</i>, vol. 11, no. 8. American Chemical Society, pp. 5752–5762, 2026.","ista":"Liu Y, Kleinhanns T, Spadaro MC, Genç A, Horta S, Jakhar N, Costanzo T, Dutkiewicz E, Arbiol J, Hong M, Ibáñez M. 2026. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. ACS Energy Letters. 11(8), 5752–5762.","mla":"Liu, Yu, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>, vol. 11, no. 8, American Chemical Society, 2026, pp. 5752–62, doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>.","short":"Y. Liu, T. Kleinhanns, M.C. Spadaro, A. Genç, S. Horta, N. Jakhar, T. Costanzo, E. Dutkiewicz, J. Arbiol, M. Hong, M. Ibáñez, ACS Energy Letters 11 (2026) 5752–5762.","chicago":"Liu, Yu, Tobias Kleinhanns, Maria Chiara Spadaro, Aziz Genç, Sharona Horta, Navita Jakhar, Tommaso Costanzo, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>."},"fulldoi":"https://doi.org/10.1021/acsenergylett.6c01499","date_created":"2026-08-18T11:34:03Z","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"NanoFab"},{"_id":"MassSpec"}],"publisher":"American Chemical Society","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"date_updated":"2026-08-19T05:53:33Z","researchdata_availability":"no","department":[{"_id":"MassSpec"},{"_id":"MaIb"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"oa":1,"author":[{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","full_name":"Liu, Yu","first_name":"Yu","orcid":"0000-0001-7313-6740","last_name":"Liu"},{"last_name":"Kleinhanns","first_name":"Tobias","full_name":"Kleinhanns, Tobias","orcid":"0000-0003-1537-7436","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425"},{"last_name":"Spadaro","full_name":"Spadaro, Maria Chiara","first_name":"Maria Chiara"},{"first_name":"Aziz","full_name":"Genç, Aziz","last_name":"Genç"},{"last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona","full_name":"Horta, Sharona"},{"last_name":"Navita","full_name":"Navita, Navita","first_name":"Navita","orcid":"0000-0001-7408-8197","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4"},{"id":"D93824F4-D9BA-11E9-BB12-F207E6697425","orcid":"0000-0001-9732-3815","full_name":"Costanzo, Tommaso","first_name":"Tommaso","last_name":"Costanzo"},{"last_name":"Dutkiewicz","id":"0601cc46-c082-11ec-9b07-bb29641d1de9","full_name":"Dutkiewicz, Ewelina","first_name":"Ewelina"},{"full_name":"Arbiol, Jordi","first_name":"Jordi","last_name":"Arbiol"},{"last_name":"Hong","first_name":"Min","full_name":"Hong, Min"},{"full_name":"Ibáñez, Maria","first_name":"Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez"}],"ddc":["540"],"day":"14","doi":"10.1021/acsenergylett.6c01499","issue":"8","file_date_updated":"2026-08-19T05:52:41Z","volume":11,"publication":"ACS Energy Letters","abstract":[{"text":"Silver selenide (Ag2Se) is a promising near-room-temperature thermoelectric material, but its narrow stoichiometric window and β–α phase transition complicate reproducible microstructure control. Here, we present a mismatch-assisted microstructure engineering strategy in which Ag2Se particles are treated with polyanionic ZnSe complexes and consolidated through the β–α transition to introduce ZnSe nanoprecipitates, Ag2Se/ZnSe interfaces, and local strain fields. The crystallographic mismatch between ZnSe and Ag2Se, together with the Zn2+/Ag+ size difference, amplifies phase-transition-induced deformation and promotes high-density dislocations with periodic strain modulations. This defect architecture suppresses grain coarsening, removes excess Ag, limits Ag-interstitial formation, and reduces lattice thermal conductivity through lattice softening and multiscale phonon scattering. Ag2Se–4%ZnSe nanocomposites achieve a peak zTmax of 1.13 at 369 K and a zTavg of 1.08 from 300 to 380 K, demonstrating mismatch-driven defect engineering through the β–α phase transition as a route for optimizing Ag2Se-based thermoelectrics.","lang":"eng"}],"das_tickbox":"0","PlanS_conform":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","publication_status":"published","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"month":"08","quality_controlled":"1","has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","publication_identifier":{"eissn":["2380-8195"]},"_id":"22734","year":"2026","file":[{"content_type":"application/pdf","date_created":"2026-08-19T05:52:41Z","relation":"main_file","success":1,"access_level":"open_access","checksum":"4d75c5a79d112c845c9eecba8838db38","file_name":"2026_ACSEnergyLetters_Liu.pdf","file_id":"22736","date_updated":"2026-08-19T05:52:41Z","file_size":6806815,"creator":"dernst"}],"type":"journal_article","status":"public","acknowledgement":"Open access funding provided by Institute of Science and Technology Austria. M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation. The Scientific Service Units (SSU) of ISTA supported this work through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Nanofabrication Facility (NNF), and the Mass Spectrometry Facility. Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (grant no. 22209034) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). M.H. acknowledges funding from Australian Research Council (FT230100316), and the high-performance computing resources provided by National Computational Infrastructure (it39) and Pawsey Supercomputing Centre (pawsey1075). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by the “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (grant no.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Authors acknowledge the use of instrumentation as well as the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member of e-DREAM. (91)","date_published":"2026-08-14T00:00:00Z","OA_type":"hybrid","title":"Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se","OA_place":"publisher","scopus_import":"1"},{"language":[{"iso":"eng"}],"date_updated":"2026-08-20T06:14:07Z","department":[{"_id":"LifeSc"}],"researchdata_availability":"yes","oa":1,"author":[{"last_name":"Hörmann","full_name":"Hörmann, Anja F.","first_name":"Anja F."},{"last_name":"Balazs","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","first_name":"Daniel","full_name":"Balazs, Daniel","orcid":"0000-0001-7597-043X"},{"first_name":"Ingo","full_name":"Breßler, Ingo","last_name":"Breßler"},{"last_name":"Klokic","first_name":"Sumea","full_name":"Klokic, Sumea"},{"full_name":"Moradi, Melika","first_name":"Melika","last_name":"Moradi"},{"full_name":"Solano, Eduardo","first_name":"Eduardo","last_name":"Solano"},{"last_name":"Stellhorn","full_name":"Stellhorn, Annika","first_name":"Annika"},{"last_name":"Pauw","full_name":"Pauw, Brian R.","first_name":"Brian R."}],"ddc":["540"],"article_type":"original","intvolume":"        59","page":"1247-1253","citation":{"ieee":"A. F. Hörmann <i>et al.</i>, “Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration,” <i>Journal of Applied Crystallography</i>, vol. 59, no. 4. International Union of Crystallography, pp. 1247–1253, 2026.","ista":"Hörmann AF, Balazs D, Breßler I, Klokic S, Moradi M, Solano E, Stellhorn A, Pauw BR. 2026. Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. Journal of Applied Crystallography. 59(4), 1247–1253.","apa":"Hörmann, A. F., Balazs, D., Breßler, I., Klokic, S., Moradi, M., Solano, E., … Pauw, B. R. (2026). Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. <i>Journal of Applied Crystallography</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/S1600576726005741\">https://doi.org/10.1107/S1600576726005741</a>","ama":"Hörmann AF, Balazs D, Breßler I, et al. Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. <i>Journal of Applied Crystallography</i>. 2026;59(4):1247-1253. doi:<a href=\"https://doi.org/10.1107/S1600576726005741\">10.1107/S1600576726005741</a>","short":"A.F. Hörmann, D. Balazs, I. Breßler, S. Klokic, M. Moradi, E. Solano, A. Stellhorn, B.R. Pauw, Journal of Applied Crystallography 59 (2026) 1247–1253.","chicago":"Hörmann, Anja F., Daniel Balazs, Ingo Breßler, Sumea Klokic, Melika Moradi, Eduardo Solano, Annika Stellhorn, and Brian R. Pauw. “Grazing-Incidence Scattering Surveyed: Towards Reference Methods for Alignment and Calibration.” <i>Journal of Applied Crystallography</i>. International Union of Crystallography, 2026. <a href=\"https://doi.org/10.1107/S1600576726005741\">https://doi.org/10.1107/S1600576726005741</a>.","mla":"Hörmann, Anja F., et al. “Grazing-Incidence Scattering Surveyed: Towards Reference Methods for Alignment and Calibration.” <i>Journal of Applied Crystallography</i>, vol. 59, no. 4, International Union of Crystallography, 2026, pp. 1247–53, doi:<a href=\"https://doi.org/10.1107/S1600576726005741\">10.1107/S1600576726005741</a>."},"fulldoi":"https://doi.org/10.1107/S1600576726005741","date_created":"2026-08-16T22:01:43Z","publisher":"International Union of Crystallography","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"_id":"22715","year":"2026","file":[{"access_level":"open_access","file_id":"22739","checksum":"8dbad0ab078338021e2cfe722211df7b","date_updated":"2026-08-20T05:51:36Z","file_name":"2026_JourAppliedCrystallography_Hoermann.pdf","file_size":6692218,"creator":"dernst","content_type":"application/pdf","date_created":"2026-08-20T05:51:36Z","relation":"main_file","success":1}],"type":"journal_article","status":"public","date_published":"2026-08-01T00:00:00Z","acknowledgement":"The authors thank all respondents for their participation in the\r\nquestionnaire. We plan to make further use of the wealth of\r\nthe dataset going forward. We thank Xenocs for sharing\r\napproximate data on GISAXS equipment sales and Adrian\r\nRennie for helpful discussions. Open access funding enabled\r\nand organized by Projekt DEAL.","OA_type":"hybrid","keyword":["grazing incidence","reference methods","calibration","standardization","community"],"title":"Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration","OA_place":"publisher","scopus_import":"1","day":"01","doi":"10.1107/S1600576726005741","issue":"4","file_date_updated":"2026-08-20T05:51:36Z","publication":"Journal of Applied Crystallography","volume":59,"abstract":[{"text":"Grazing-incidence small-angle scattering (GISAS) is a relatively young technique with important applications in thin-film technology and untapped potential when it comes to 2D analysis on an absolute intensity scale. Approaching standardization and reference methods early is foundational for reproducibility and comparability across laboratories and reduction of systematic error sources. It underpins trust in data obtained and accelerates innovation by ensuring that scientists work from a common methodological baseline. Accordingly, obtaining reproducible results from different GISAS instruments requires an agreement on how measurements are performed, instruments calibrated and terms defined. To pave the way for standardization and reference methods, we surveyed GISAS practitioners on what comes before an experiment: hardware, software, sample alignment and instrument calibration. Twenty-two questions were designed to elucidate the state of the art, which can be used for the development of reference methods. Our data on 27 instruments provide the basis for standardization. With very few exceptions, we found laboratories prepared to implement future reference methods, but no consensus emerges naturally for sample alignment and instrument calibration. We, that is the GISAS community, are thus in a position to embark on the journey of standardization.","lang":"eng"}],"das_tickbox":"1","oa_version":"Published Version","PlanS_conform":"1","dataavailabilitystatement":"The response data are available at https://doi.org/10.5281/\r\nzenodo.18712813. The literate programming source of this\r\nwork is available at https://doi.org/10.5281/zenodo.18713631.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"no","publication_status":"published","month":"08","quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","publication_identifier":{"issn":["0021-8898"],"eissn":["1600-5767"]}},{"das_tickbox":"0","oa_version":"Published Version","PlanS_conform":"1","abstract":[{"lang":"eng","text":"We give an algorithm that, with high probability, maintains a (1-ε)-approximate s-t maximum flow in undirected, uncapacitated n-vertex graphs undergoing m edge insertions in Õ(m+ n F^*/ε) total update time, where F^{*} is the maximum flow on the final graph. This is the first algorithm to achieve polylogarithmic amortized update time for dense graphs (m = Ω(n²)), and more generally, for graphs where F^* = Õ(m/n). At the heart of our incremental algorithm is the residual graph sparsification technique of Karger and Levine [SICOMP '15], originally designed for computing exact maximum flows in the static setting. Our main contributions are (i) showing how to maintain such sparsifiers for approximate maximum flows in the incremental setting and (ii) generalizing the cut sparsification framework of Fung et al. [SICOMP '19] from undirected graphs to balanced directed graphs."}],"issue":"3","volume":22,"file_date_updated":"2026-08-20T06:19:51Z","publication":"ACM Transactions on Algorithms","day":"06","doi":"10.1145/3816252","has_accepted_license":"1","article_processing_charge":"Yes","publication_identifier":{"issn":["1549-6325"],"eissn":["1549-6333"]},"month":"07","quality_controlled":"1","supplementarymaterial":"yes","project":[{"grant_number":"101019564","call_identifier":"H2020","name":"The design and evaluation of modern fully dynamic data structures","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62"},{"_id":"34def286-11ca-11ed-8bc3-da5948e1613c","name":"Efficient algorithms","grant_number":"Z00422"},{"_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","name":"Static and Dynamic Hierarchical Graph Decompositions","grant_number":"I05982"},{"grant_number":"P33775","_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","name":"Fast Algorithms for a Reactive Network Layer"}],"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"M. Henzinger: This project has received funding from the European Research Council (ERC) under the European Union’s\r\nHorizon 2020 research and innovation programme (MoDynStruct, No. 101019564)   and the Austrian Science Fund\r\n(FWF) grant DOI 10.55776/Z422, grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775 with additional funding from the\r\nnetidee SCIENCE Stiftung, 2020–2024. Views and opinions expressed are those of the author(s) only and do not necessarily\r\nreflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor\r\nthe granting authority can be held responsible for them","date_published":"2026-07-06T00:00:00Z","related_material":{"record":[{"relation":"earlier_version","status":"public","id":"21280"}]},"type":"journal_article","status":"public","article_number":"31","_id":"22716","year":"2026","file":[{"relation":"main_file","success":1,"content_type":"application/pdf","date_created":"2026-08-20T06:19:51Z","creator":"dernst","access_level":"open_access","file_name":"2026_TransactionsAlgorithms_Goranci.pdf","checksum":"97969d26dab25c3a35be3ae4dd0fd9ee","date_updated":"2026-08-20T06:19:51Z","file_id":"22740","file_size":2272512}],"scopus_import":"1","title":"Incremental approximate maximum flow via residual graph sparsification","OA_place":"publisher","OA_type":"gold","citation":{"mla":"Goranci, Gramoz, et al. “Incremental Approximate Maximum Flow via Residual Graph Sparsification.” <i>ACM Transactions on Algorithms</i>, vol. 22, no. 3, 31, ACM, 2026, doi:<a href=\"https://doi.org/10.1145/3816252\">10.1145/3816252</a>.","chicago":"Goranci, Gramoz, Monika Henzinger, Harald Räcke, and A. R. Sricharan. “Incremental Approximate Maximum Flow via Residual Graph Sparsification.” <i>ACM Transactions on Algorithms</i>. ACM, 2026. <a href=\"https://doi.org/10.1145/3816252\">https://doi.org/10.1145/3816252</a>.","short":"G. Goranci, M. Henzinger, H. Räcke, A.R. Sricharan, ACM Transactions on Algorithms 22 (2026).","apa":"Goranci, G., Henzinger, M., Räcke, H., &#38; Sricharan, A. R. (2026). Incremental approximate maximum flow via residual graph sparsification. <i>ACM Transactions on Algorithms</i>. ACM. <a href=\"https://doi.org/10.1145/3816252\">https://doi.org/10.1145/3816252</a>","ama":"Goranci G, Henzinger M, Räcke H, Sricharan AR. Incremental approximate maximum flow via residual graph sparsification. <i>ACM Transactions on Algorithms</i>. 2026;22(3). doi:<a href=\"https://doi.org/10.1145/3816252\">10.1145/3816252</a>","ista":"Goranci G, Henzinger M, Räcke H, Sricharan AR. 2026. Incremental approximate maximum flow via residual graph sparsification. ACM Transactions on Algorithms. 22(3), 31.","ieee":"G. Goranci, M. Henzinger, H. Räcke, and A. R. Sricharan, “Incremental approximate maximum flow via residual graph sparsification,” <i>ACM Transactions on Algorithms</i>, vol. 22, no. 3. ACM, 2026."},"fulldoi":"https://doi.org/10.1145/3816252","corr_author":"1","external_id":{"arxiv":["2502.09105"]},"intvolume":"        22","article_type":"original","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publisher":"ACM","date_created":"2026-08-16T22:01:43Z","researchdata_availability":"no","date_updated":"2026-08-20T06:28:01Z","language":[{"iso":"eng"}],"department":[{"_id":"MoHe"}],"ddc":["000"],"author":[{"last_name":"Goranci","full_name":"Goranci, Gramoz","first_name":"Gramoz"},{"id":"540c9bbd-f2de-11ec-812d-d04a5be85630","orcid":"0000-0002-5008-6530","first_name":"Monika H","full_name":"Henzinger, Monika H","last_name":"Henzinger"},{"first_name":"Harald","full_name":"Räcke, Harald","last_name":"Räcke"},{"full_name":"Sricharan, A. R.","first_name":"A. R.","last_name":"Sricharan"}],"arxiv":1,"oa":1,"ec_funded":1},{"article_type":"original","intvolume":"        12","external_id":{"pmid":["42555737"]},"page":"eadw5487","citation":{"mla":"Varela Martínez, Irene, et al. “Early Fate Diversification of Radial Glial Progenitors during Corticogenesis.” <i>Science Advances</i>, vol. 12, no. 32, AAAS, 2026, p. eadw5487, doi:<a href=\"https://doi.org/10.1126/sciadv.adw5487\">10.1126/sciadv.adw5487</a>.","chicago":"Varela Martínez, Irene, Ana Villalba Requena, Jorge García-Marqués, Alfonso Aguilera, Diogo S. Castro, Simon Hippenmeyer, and Marta Nieto. “Early Fate Diversification of Radial Glial Progenitors during Corticogenesis.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.adw5487\">https://doi.org/10.1126/sciadv.adw5487</a>.","short":"I. Varela Martínez, A. Villalba Requena, J. García-Marqués, A. Aguilera, D.S. Castro, S. Hippenmeyer, M. Nieto, Science Advances 12 (2026) eadw5487.","apa":"Varela Martínez, I., Villalba Requena, A., García-Marqués, J., Aguilera, A., Castro, D. S., Hippenmeyer, S., &#38; Nieto, M. (2026). Early fate diversification of radial glial progenitors during corticogenesis. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.adw5487\">https://doi.org/10.1126/sciadv.adw5487</a>","ama":"Varela Martínez I, Villalba Requena A, García-Marqués J, et al. Early fate diversification of radial glial progenitors during corticogenesis. <i>Science Advances</i>. 2026;12(32):eadw5487. doi:<a href=\"https://doi.org/10.1126/sciadv.adw5487\">10.1126/sciadv.adw5487</a>","ieee":"I. Varela Martínez <i>et al.</i>, “Early fate diversification of radial glial progenitors during corticogenesis,” <i>Science Advances</i>, vol. 12, no. 32. AAAS, p. eadw5487, 2026.","ista":"Varela Martínez I, Villalba Requena A, García-Marqués J, Aguilera A, Castro DS, Hippenmeyer S, Nieto M. 2026. Early fate diversification of radial glial progenitors during corticogenesis. Science Advances. 12(32), eadw5487."},"fulldoi":"https://doi.org/10.1126/sciadv.adw5487","date_created":"2026-08-16T22:01:43Z","DOAJ_listed":"1","publisher":"AAAS","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"researchdata_availability":"yes","department":[{"_id":"SiHi"}],"date_updated":"2026-08-20T05:45:28Z","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Varela Martínez","full_name":"Varela Martínez, Irene","first_name":"Irene","id":"a69b5985-8829-11f0-8fc2-d0af58f64471"},{"id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana","full_name":"Villalba Requena, Ana","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena"},{"full_name":"García-Marqués, Jorge","first_name":"Jorge","last_name":"García-Marqués"},{"full_name":"Aguilera, Alfonso","first_name":"Alfonso","last_name":"Aguilera"},{"full_name":"Castro, Diogo S.","first_name":"Diogo S.","last_name":"Castro"},{"full_name":"Hippenmeyer, Simon","first_name":"Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer"},{"full_name":"Nieto, Marta","first_name":"Marta","last_name":"Nieto"}],"ddc":["570"],"day":"07","doi":"10.1126/sciadv.adw5487","issue":"32","volume":12,"publication":"Science Advances","file_date_updated":"2026-08-20T05:39:32Z","abstract":[{"text":"Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the cerebral cortex through incompletely understood processes. We combined Mosaic Analysis with Double Markers at embryonic stages (E)12.5 and E13.5 with early postnatal callosal tracing to dissect RGP lineage progression. We find that multipotent RGPs generate all extra-telencephalic (ET) and intra-telencephalic (IT) PNs via parallel sublineages that emerge simultaneously at neurogenesis onset. ET-PN production progresses exclusively via small, self-consuming lineages; IT-PN lineages feature RGPs generating large translaminar outputs. The early emergence of IT-PN–fated RGPs, coinciding with a switch to direct neurogenesis, contributes to the stereotyped population-level progression of the multipotent lineage. We also identify POU3F transcription factors as candidate regulators of IT-PN fate via noncanonical mitotic chromatin binding. The results support a model whereby IT- and ET-PNs arise from an early bifurcation and parallel specification within the multipotent RGP lineage.","lang":"eng"}],"das_tickbox":"1","oa_version":"Published Version","PlanS_conform":"1","dataavailabilitystatement":"All data and code needed to evaluate and reproduce the results in the paper are present in the paper and/or the Supplementary Materials. Source data underlying all figures (including the clonal atlas) are provided in the Supplementary Materials. RnA-seq analysis code has been deposited in Zenodo (dOi: 10.5281/zenodo.14609057). this study did not generate new materials.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","publication_status":"published","pmid":1,"month":"08","quality_controlled":"1","has_accepted_license":"1","article_processing_charge":"Yes","publication_identifier":{"eissn":["2375-2548"]},"_id":"22714","file":[{"creator":"dernst","access_level":"open_access","checksum":"487c3703387080e8f3c4675d67763f0e","file_name":"2026_ScienceAdv_VarelaMartinez.pdf","file_id":"22738","date_updated":"2026-08-20T05:39:32Z","file_size":3056744,"relation":"main_file","success":1,"content_type":"application/pdf","date_created":"2026-08-20T05:39:32Z"}],"year":"2026","type":"journal_article","status":"public","date_published":"2026-08-07T00:00:00Z","acknowledgement":"We thank M. caouyette for the plasmid construction for Pou3f1overexpression; d. Pinto-Benito for valuable assistance with shRnA validation in n2A cells andqPcR experiments; c. Varela-Martínez for help with the code for graphical analysis; allmembers from the nieto’s lab for comment on the manuscript, specially to F. Martín for theinsightful discussions; J. c. Oliveros and J. A. García from the computational service of the cnBfor help with the analysis of RnAseq dataset; c. O. Sorzano for help with statistical analysis; andA. Oña and the service of Advance Optical Microscopy of the cnB for technical advice.Funding: i.V.-M. holds a fellowship funded by MciciU (PRe-2018-083376) and 2023 eMBOscientific exchange grant 10214. the work was funded by grants to M.n. (Pid2020-112831GB- i00 and Pid2023-146322nB- i00 by Mcin/Aei/10.13039/501100011033 and by“eRdF A way of making europe”).","OA_type":"gold","title":"Early fate diversification of radial glial progenitors during corticogenesis","OA_place":"publisher","scopus_import":"1"},{"publication":"Proceedings of the National Academy of Sciences","volume":123,"file_date_updated":"2026-08-20T05:34:25Z","issue":"24","day":"16","doi":"10.1073/pnas.2524065123","PlanS_conform":"1","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Sleep need is associated with both circuit dynamics and widespread synaptic plasticity, yet the specific synaptic changes underlying sleep homeostasis remain incompletely understood. In Drosophila, sleep loss has been shown to trigger plasticity of the presynaptic active zone, marked by increasing levels of the ELKS-family scaffold protein Bruchpilot (BRP). By titrating brp gene copy number, we previously established a presynapse-specific, dosage-dependent paradigm that modulates sleep pressure. Here, to elucidate the molecular landscape of this plasticity, we performed synapse-enriched integrated-omics. Proteomic and bioinformatic analyses revealed changes in immune and stress response pathways and local translation control. Strikingly, phospho-proteomic analysis uncovered a global shift toward hypophosphorylation, particularly in presynaptic proteins, indicating a reprogramming of the phosphorylation–dephosphorylation balance. This presynaptic hypophosphorylation is likely contributed by reduced activity of Protein Kinase A (PKA) and enhanced substrate affinity of Protein Phosphatase 1 (PP1) mediated by its regulatory subunit Spinophilin (Spn). Manipulating either PKA or PP1 activity was sufficient to suppress BRP-modulated sleep phenotypes. We propose that presynaptic hypophosphorylation constitutes a molecular signature of local synaptic remodeling that adaptively tunes sleep need via reversible posttranslational modification, a mechanism likely conserved across species."}],"publication_status":"published","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","publication_identifier":{"issn":["0027-8424","1091-6490"]},"article_processing_charge":"Yes (in subscription journal)","has_accepted_license":"1","quality_controlled":"1","month":"06","file":[{"creator":"dernst","access_level":"open_access","file_id":"22737","file_name":"2026_PNAS_Piao.pdf","date_updated":"2026-08-20T05:34:25Z","checksum":"3727c5ad18c1e9c65672fbb01ac6ea04","file_size":3915000,"relation":"main_file","success":1,"content_type":"application/pdf","date_created":"2026-08-20T05:34:25Z"}],"year":"2026","_id":"22733","article_number":"e2524065123","date_published":"2026-06-16T00:00:00Z","status":"public","type":"journal_article","OA_type":"hybrid","scopus_import":"1","OA_place":"publisher","title":"Active zone plasticity couples sleep need to presynaptic hypophosphorylation","intvolume":"       123","article_type":"original","fulldoi":"https://doi.org/10.1073/pnas.2524065123","citation":{"short":"C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, S.J. Sigrist, Proceedings of the National Academy of Sciences 123 (2026).","chicago":"Piao, Chengji, Ewelina Dutkiewicz, Laxmikanth Kollipara, Albert Sickmann, Sheng Huang, and Stephan J. Sigrist. “Active Zone Plasticity Couples Sleep Need to Presynaptic Hypophosphorylation.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2026. <a href=\"https://doi.org/10.1073/pnas.2524065123\">https://doi.org/10.1073/pnas.2524065123</a>.","mla":"Piao, Chengji, et al. “Active Zone Plasticity Couples Sleep Need to Presynaptic Hypophosphorylation.” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 24, e2524065123, National Academy of Sciences, 2026, doi:<a href=\"https://doi.org/10.1073/pnas.2524065123\">10.1073/pnas.2524065123</a>.","ieee":"C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, and S. J. Sigrist, “Active zone plasticity couples sleep need to presynaptic hypophosphorylation,” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 24. National Academy of Sciences, 2026.","ista":"Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. 2026. Active zone plasticity couples sleep need to presynaptic hypophosphorylation. Proceedings of the National Academy of Sciences. 123(24), e2524065123.","apa":"Piao, C., Dutkiewicz, E., Kollipara, L., Sickmann, A., Huang, S., &#38; Sigrist, S. J. (2026). Active zone plasticity couples sleep need to presynaptic hypophosphorylation. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2524065123\">https://doi.org/10.1073/pnas.2524065123</a>","ama":"Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. Active zone plasticity couples sleep need to presynaptic hypophosphorylation. <i>Proceedings of the National Academy of Sciences</i>. 2026;123(24). doi:<a href=\"https://doi.org/10.1073/pnas.2524065123\">10.1073/pnas.2524065123</a>"},"external_id":{"pmid":["42258713"]},"publisher":"National Academy of Sciences","date_created":"2026-08-18T10:46:33Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2026-08-20T05:35:33Z","language":[{"iso":"eng"}],"oa":1,"ddc":["570"],"author":[{"last_name":"Piao","full_name":"Piao, Chengji","first_name":"Chengji"},{"last_name":"Dutkiewicz","id":"0601cc46-c082-11ec-9b07-bb29641d1de9","full_name":"Dutkiewicz, Ewelina","first_name":"Ewelina"},{"last_name":"Kollipara","first_name":"Laxmikanth","full_name":"Kollipara, Laxmikanth"},{"first_name":"Albert","full_name":"Sickmann, Albert","last_name":"Sickmann"},{"last_name":"Huang","first_name":"Sheng","full_name":"Huang, Sheng"},{"last_name":"Sigrist","first_name":"Stephan J.","full_name":"Sigrist, Stephan J."}]},{"researchdata_availability":"yes","department":[{"_id":"JiFr"},{"_id":"EvBe"}],"language":[{"iso":"eng"}],"date_updated":"2026-08-20T06:45:46Z","author":[{"last_name":"Liu","full_name":"Liu, Juan","first_name":"Juan"},{"last_name":"Zhai","first_name":"Ning","full_name":"Zhai, Ning"},{"last_name":"Zhang","full_name":"Zhang, Shiyi","first_name":"Shiyi"},{"last_name":"Tamada","first_name":"Yosuke","full_name":"Tamada, Yosuke"},{"first_name":"Tonghui","full_name":"Li, Tonghui","last_name":"Li"},{"full_name":"Zhang, Linfan","first_name":"Linfan","last_name":"Zhang"},{"full_name":"Chen, Tong","first_name":"Tong","last_name":"Chen"},{"first_name":"Chenglin","full_name":"Wang, Chenglin","last_name":"Wang"},{"first_name":"Jian","full_name":"Yang, Jian","last_name":"Yang"},{"full_name":"Gao, Jiaqi","first_name":"Jiaqi","last_name":"Gao"},{"id":"4B7E523C-F248-11E8-B48F-1D18A9856A87","full_name":"Li, Xiang","first_name":"Xiang","last_name":"Li"},{"full_name":"Zhou, Junhui","first_name":"Junhui","last_name":"Zhou"},{"full_name":"Zhang, Yonghong","first_name":"Yonghong","last_name":"Zhang"},{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","full_name":"Liu, Yu","first_name":"Yu","orcid":"0000-0001-7313-6740","last_name":"Liu"},{"last_name":"Wang","full_name":"Wang, Yuan","first_name":"Yuan"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jiří","full_name":"Friml, Jiří","last_name":"Friml"},{"first_name":"Eva","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková"},{"last_name":"Li","first_name":"Chen","full_name":"Li, Chen"},{"last_name":"Xu","full_name":"Xu, Lin","first_name":"Lin"},{"first_name":"Luqi","full_name":"Huang, Luqi","last_name":"Huang"}],"ddc":["580"],"oa":1,"external_id":{"pmid":["42350386"]},"citation":{"apa":"Liu, J., Zhai, N., Zhang, S., Tamada, Y., Li, T., Zhang, L., … Huang, L. (2026). Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-74881-5\">https://doi.org/10.1038/s41467-026-74881-5</a>","ama":"Liu J, Zhai N, Zhang S, et al. Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-74881-5\">10.1038/s41467-026-74881-5</a>","ista":"Liu J, Zhai N, Zhang S, Tamada Y, Li T, Zhang L, Chen T, Wang C, Yang J, Gao J, Li X, Zhou J, Zhang Y, Liu Y, Wang Y, Friml J, Benková E, Li C, Xu L, Huang L. 2026. Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. Nature Communications. 17, 7994.","ieee":"J. Liu <i>et al.</i>, “Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","mla":"Liu, Juan, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature Communications</i>, vol. 17, 7994, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-74881-5\">10.1038/s41467-026-74881-5</a>.","chicago":"Liu, Juan, Ning Zhai, Shiyi Zhang, Yosuke Tamada, Tonghui Li, Linfan Zhang, Tong Chen, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-74881-5\">https://doi.org/10.1038/s41467-026-74881-5</a>.","short":"J. Liu, N. Zhai, S. Zhang, Y. Tamada, T. Li, L. Zhang, T. Chen, C. Wang, J. Yang, J. Gao, X. Li, J. Zhou, Y. Zhang, Y. Liu, Y. Wang, J. Friml, E. Benková, C. Li, L. Xu, L. Huang, Nature Communications 17 (2026)."},"fulldoi":"https://doi.org/10.1038/s41467-026-74881-5","article_type":"original","intvolume":"        17","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"date_created":"2026-08-16T22:01:42Z","DOAJ_listed":"1","publisher":"Springer Nature","type":"journal_article","status":"public","date_published":"2026-08-07T00:00:00Z","acknowledgement":"The authors are grateful to Professor Linfeng Li from the School of Life Science, Fudan University, for his assistance during the ginseng genome annotation. This work was supported by Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources (2060302-2401-08 to L.X. and J.L.), the National Natural Science Foundation of China (82373987 to J.L., 31701294 to L.X., 32225007 to L.X., and 32300285 to N.Z.), the Fundamental Research Funds for the Central public welfare research institutes (ZZ13-YQ-093, ZZXT202508 to J.L.), the CACMS Innovation Fund (CI2025G00-06 to J.L.), the Principle Investigator Program (HBMUPI202104 to Y.Z.), the Key R&D Program of Shandong Province, China (2024LZGC025 to L.X.), the National Key R&D Program of China (2024YFF1000700/2023YFE0101100 to L.X.), Strategic Priority Research Program of Chinese Academy of Sciences (XDB0630000 to L.X.), and China Postdoctoral Science Foundation (2023M733490 to N.Z.).","_id":"22712","article_number":"7994","year":"2026","file":[{"relation":"main_file","success":1,"content_type":"application/pdf","date_created":"2026-08-20T06:44:33Z","creator":"dernst","access_level":"open_access","date_updated":"2026-08-20T06:44:33Z","file_id":"22742","checksum":"0b4ff29f0d0168b11be32a5f22ded9e4","file_name":"2026_NatureComm_Liu.pdf","file_size":2429551}],"title":"Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production","OA_place":"publisher","scopus_import":"1","OA_type":"gold","abstract":[{"text":"Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside metabolites. However, the long cultivation cycle and susceptibility to diseases hinder the advancement of the ginseng industry. Here, we demonstrate that the embryonic protoderm of ginseng can efficiently produce ginsenosides. Single-cell transcriptome and mass spectrometry imaging analyses reveal that ginsenosides accumulate in the protoderm of ginseng embryonic callus (EC) at levels comparable to those in forest ginseng. Epigenetic analyses indicate that elevated histone acetylation and enhanced chromatin accessibility at regeneration- and ginsenoside metabolism-related gene loci are associated with the ginsenoside-producing capacity of EC. Increasing histone acetylation levels or overexpressing the regeneration-related WUSCHEL-RELATED HOMEOBOX11 (WOX11) gene further enhances ginsenoside production in EC. Our findings suggest that the protoderm of EC could serve as an in situ biological compartment for high-efficiency ginsenoside producion, offering a complementary approach to traditional ginseng cultivation.","lang":"eng"}],"das_tickbox":"1","oa_version":"Published Version","doi":"10.1038/s41467-026-74881-5","day":"07","volume":17,"file_date_updated":"2026-08-20T06:44:33Z","publication":"Nature Communications","month":"08","quality_controlled":"1","article_processing_charge":"Yes","has_accepted_license":"1","publication_identifier":{"eissn":["2041-1723"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"The RNA-seq data generated in this study have been deposited in the GSA database under accession code CRA008967. The scRNA-seq data generated in this study have been deposited in the GSA database under accession code CRA026200. The ATAC-seq data generated in this study have been deposited in the GSA database under accession code CRA008969. The ChIP-seq data generated in this study have been deposited in the GSA database under accession code CRA008968. Single-cell RNA-seq data and scripts are publicly available on Zenodo (https://zenodo.org/records/20392012). Primers are in Supplemental Table 5. Source data are provided with this paper.","supplementarymaterial":"yes","pmid":1,"publication_status":"published"},{"file_date_updated":"2026-08-20T07:35:05Z","doi":"10.15479/AT-ISTA-22687","day":"20","oa_version":"None","abstract":[{"lang":"eng","text":"Understanding enzyme function requires characterizing not only static structure but also dynamics and ligand interactions. NMR spectroscopy provides this insight at atomic resolution, yet for large proteins the difficulty of resonance assignment has largely confined such studies to systems below ∼50 kDa, or to observing only methyl groups. Here we present an integrated magic-angle spinning (MAS) and solution NMR study of the 134 kDa tetrameric malate dehydrogenase from Ignicoccus islandicus (IiMDH), an enzyme of particular interest as an evolutionary intermediate between allosteric lactate\r\ndehydrogenases and non-allosteric malate dehydrogenases. By combining high-dimensional (up to 4D) MAS NMR experiments on sedimented protein with solution NMR, we achieved 92% backbone heavy- atom assignment and 91% assignment of all Ile-δ1, Leu-δ1/-δ2, Val-γ1/-γ2, Met-ε and Thr-γ methyl groups. Building on these assignments, we use various probes of backbone and sidechain dynamics: elevated MAS NMR 15N rotating-frame relaxation (R1ρ) points to microsecond motions in functionally critical regions, including the catalytic loop and the mobile surface loop. Complementary methyl-axis order parameters from solution NMR identified additional flexible sites in the hydrophobic core. Chemical shift perturbation experiments upon addition of the substrate analogue oxamate, monitored via backbone 1H-15N TROSY, revealed both active-site contacts and responses in helices α2F and α3G, regions implicated in allosteric signal transmission. The integrated approach demonstrated here exploits the distinct strengths of MAS and solution NMR, and provides a comprehensive view of structure, dynamics, and substrate interactions in a large oligomeric enzyme that would not be accessible by either technique alone."}],"project":[{"grant_number":"I05812","name":"AlloSpace. The emergence and mechanisms of allostery","_id":"eb9c82eb-77a9-11ec-83b8-aadd536561cf"}],"doi_confirm":"1","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","article_processing_charge":"No","has_accepted_license":"1","month":"08","year":"2026","contributor":[{"first_name":"Federico","orcid":"0000-0002-9043-136X","contributor_type":"researcher","id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","last_name":"Napoli"},{"contributor_type":"project_leader","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","first_name":"Paul","orcid":"0000-0002-9350-7606","last_name":"Schanda"},{"last_name":"Singh","contributor_type":"project_member","id":"a3089acd-6806-11ee-bacc-f0c7d500ad20","first_name":"Rajkumar"},{"last_name":"Kapitonova","first_name":"Anna","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471","contributor_type":"project_member"},{"contributor_type":"project_member","first_name":"Virgil","last_name":"Aitenbichler"},{"last_name":"Toscano","first_name":"Giorgia","contributor_type":"project_member","id":"334a5e40-8747-11f0-b671-ba1f5154b4b4"},{"first_name":"Barbara","contributor_type":"data_collector","last_name":"Perrone"}],"file":[{"file_size":59096,"file_id":"22725","checksum":"dd23db23f7e75bafad6c67381163c1e2","date_updated":"2026-08-18T07:13:26Z","file_name":"Pulse_parameters.xlsx","access_level":"open_access","creator":"fnapoli","date_created":"2026-08-18T07:13:26Z","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","success":1,"relation":"main_file"},{"creator":"fnapoli","file_size":3591173,"checksum":"a7ad194d8d7f780725bc2c60c63d686d","date_updated":"2026-08-18T07:16:00Z","file_id":"22726","file_name":"Scripts_submission.zip","access_level":"open_access","success":1,"relation":"main_file","date_created":"2026-08-18T07:16:00Z","content_type":"application/zip"},{"access_level":"open_access","file_id":"22727","date_updated":"2026-08-18T07:15:59Z","file_name":"FLYA_runs.zip","checksum":"dc099c298844973512ab224464964a1a","file_size":28750919,"creator":"fnapoli","content_type":"application/zip","date_created":"2026-08-18T07:15:59Z","relation":"main_file","success":1},{"success":1,"relation":"main_file","content_type":"application/zip","date_created":"2026-08-18T07:33:47Z","creator":"fnapoli","file_name":"spectra_Bruker.zip","file_id":"22728","checksum":"04bcce8eb20c90089cbd2fb5e0c50a7f","date_updated":"2026-08-18T07:33:47Z","file_size":3824856998,"access_level":"open_access"},{"date_created":"2026-08-18T08:03:33Z","content_type":"application/zip","relation":"main_file","success":1,"access_level":"open_access","file_size":17880653,"date_updated":"2026-08-18T08:03:33Z","file_id":"22729","file_name":"Titration_data.zip","checksum":"91c1161ca98632ed643d2b564395da5b","creator":"fnapoli"},{"success":1,"relation":"main_file","date_created":"2026-08-20T07:35:05Z","content_type":"text/plain","creator":"arashid","file_size":868,"file_id":"22743","date_updated":"2026-08-20T07:35:05Z","file_name":"README.txt","checksum":"ca2cf03b82656ae2858931d4391a3158","access_level":"open_access"}],"_id":"22687","acknowledgement":"This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra Rovó, Megha Mohan and Margarita Valhondo Falcón for excellent support of the NMR facility.","date_published":"2026-08-20T00:00:00Z","status":"public","type":"research_data","OA_place":"repository","title":"Data and scripts for: \"Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme\"","fulldoi":"https://doi.org/10.15479/AT-ISTA-22687","citation":{"short":"P. Schanda, F. Napoli, (2026).","chicago":"Schanda, Paul, and Federico Napoli. “Data and Scripts for: ‘Integrated Solid/Solution NMR Assignment Allows Mapping Dynamics and Ligand Binding in a 134 KDa Enzyme.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">https://doi.org/10.15479/AT-ISTA-22687</a>.","mla":"Schanda, Paul, and Federico Napoli. <i>Data and Scripts for: “Integrated Solid/Solution NMR Assignment Allows Mapping Dynamics and Ligand Binding in a 134 KDa Enzyme.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>.","ista":"Schanda P, Napoli F. 2026. Data and scripts for: ‘Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>.","ieee":"P. Schanda and F. Napoli, “Data and scripts for: ‘Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.’” Institute of Science and Technology Austria, 2026.","ama":"Schanda P, Napoli F. Data and scripts for: “Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>","apa":"Schanda, P., &#38; Napoli, F. (2026). Data and scripts for: “Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">https://doi.org/10.15479/AT-ISTA-22687</a>"},"corr_author":"1","publisher":"Institute of Science and Technology Austria","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"date_created":"2026-08-12T16:12:19Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)"},"department":[{"_id":"PaSc"}],"date_updated":"2026-08-20T07:40:15Z","oa":1,"author":[{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","orcid":"0000-0002-9350-7606","full_name":"Schanda, Paul","first_name":"Paul","last_name":"Schanda"},{"id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","orcid":"0000-0002-9043-136X","full_name":"Napoli, Federico","first_name":"Federico","last_name":"Napoli"}]},{"OA_place":"publisher","title":"Equivariant K-theory of affine Grassmannians in representation theory and arithmetic","status":"public","related_material":{"record":[{"relation":"part_of_dissertation","id":"21751","status":"public"},{"status":"public","id":"22693","relation":"part_of_dissertation"}]},"type":"dissertation","date_published":"2026-08-05T00:00:00Z","acknowledgement":"It was funded by a DOC Fellowship of the Austrian Academy of Sciences entitled Arithmetic,\r\ngeometry, topology and representation theory arising from the affine Grassmannian. It was\r\nfurther funded by the Austrian Science Fund FWF 10.55776/P35847, and an Erasmus+ staff\r\nmobility training. \r\n","file":[{"content_type":"application/pdf","date_created":"2026-08-14T11:42:31Z","relation":"main_file","access_level":"open_access","date_updated":"2026-08-14T11:42:31Z","file_name":"2026_Löwit_Jakub_Thesis.pdf","checksum":"2d0be77791dc296621c6c0f76be9d0d7","file_id":"22709","file_size":1574709,"creator":"jloewit"},{"relation":"source_file","date_created":"2026-08-14T11:42:42Z","content_type":"application/zip","creator":"jloewit","file_size":1085118,"date_updated":"2026-08-14T11:42:42Z","file_name":"2026_Löwit_Jakub_Source_files.zip","file_id":"22710","checksum":"61bde4b58c1e6c7baeb561e41f82659b","access_level":"closed"}],"year":"2026","degree_awarded":"PhD","_id":"22694","month":"08","publication_identifier":{"issn":["2663-337X"]},"has_accepted_license":"1","article_processing_charge":"No","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication_status":"published","project":[{"grant_number":"27004","_id":"901e2a43-16d5-11f0-9cad-9cead34748d6","name":"Arithmetic, geometry, topology and representation theory arising from the affine Grassmannian"},{"_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3","name":"Geometry of the tip of the global nilpotent cone","grant_number":"P35847"}],"doi_confirm":"1","abstract":[{"lang":"eng","text":"We develop and employ techniques from equivariant algebraic K-theory and related invariants\r\nin the context of geometric representation theory, in both arithmetic and topological situations.\r\nWe showcase the use of such techniques on the affine Grassmannian Gr, a space of fundamental\r\ninterest in the geometric Langlands program.\r\n\r\nIt is a deep development of mathematics of the last century that many concrete, yet combina-\r\ntorially complex algebraic problems may be effectively studied through the lens of algebraic\r\ngeometry. The objects of interest can be often realized as cohomological invariants of algebraic\r\nvarieties, and good understanding of their geometry sheds light into the original questions.\r\nSuch techniques have seen immense applications in the Langlands program, where they go\r\nunder the label of geometric representation theory.\r\n\r\nOne source of powerful invariants in algebraic geometry comes from algebraic K-theory,\r\nHochschild homology, and their relatives. These localizing invariants contain large amount\r\nof information, but are quite hard to compute. For this reason, their usage in geometric\r\nrepresentation theory has been limited.\r\n\r\nThe aim of this thesis is to showcase how to control such invariants in the situations of\r\ninterest and use them to obtain new insights. We start by reinterpreting equivariant Hochschild\r\nhomology in terms of functions on certain fixed-point schemes, which are of independent\r\ninterest. We compare it to equivariant K-theory via the trace map. We give new computations\r\nand comparisons of such invariants of affine Schubert varieties in Gr, including arithmetic\r\nsituations. We show that they behave much better than expected.\r\n\r\nWe finally utilize this circle of ideas in a purely topological setting. We describe the varying\r\nfixed points of the extended torus action on the affine Grassmannian, and use it to compute\r\nits equivariant topological K-theory ring. The answer is nontrivial and verifies an outstanding\r\nconjecture in the subject.\r\n\r\nWe compare, partly conjecturally, the resulting K-theory ring to the completed center of an\r\nintegral even hybrid quantum group and its deformed quantum category O. This gives a\r\ngenuine application of our computations in pure representation theory."}],"supervisor":[{"last_name":"Hausel","orcid":"0000-0002-9582-2634","first_name":"Tamás","full_name":"Hausel, Tamás","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87"}],"oa_version":"Published Version","doi":"10.15479/AT-ISTA-22694","day":"05","file_date_updated":"2026-08-14T11:42:42Z","author":[{"last_name":"Löwit","id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0","full_name":"Löwit, Jakub","first_name":"Jakub"}],"ddc":["510","516","512","514","513"],"oa":1,"department":[{"_id":"GradSch"},{"_id":"TaHa"}],"language":[{"iso":"eng"}],"date_updated":"2026-08-26T06:53:55Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"alternative_title":["ISTA Thesis"],"date_created":"2026-08-12T14:05:36Z","publisher":"Institute of Science and Technology Austria","corr_author":"1","page":"185","fulldoi":"https://doi.org/10.15479/AT-ISTA-22694","citation":{"short":"J. Löwit, Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic, Institute of Science and Technology Austria, 2026.","chicago":"Löwit, Jakub. “Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22694\">https://doi.org/10.15479/AT-ISTA-22694</a>.","mla":"Löwit, Jakub. <i>Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22694\">10.15479/AT-ISTA-22694</a>.","ista":"Löwit J. 2026. Equivariant K-theory of affine Grassmannians in representation theory and arithmetic. Institute of Science and Technology Austria.","ieee":"J. Löwit, “Equivariant K-theory of affine Grassmannians in representation theory and arithmetic,” Institute of Science and Technology Austria, 2026.","ama":"Löwit J. Equivariant K-theory of affine Grassmannians in representation theory and arithmetic. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22694\">10.15479/AT-ISTA-22694</a>","apa":"Löwit, J. (2026). <i>Equivariant K-theory of affine Grassmannians in representation theory and arithmetic</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22694\">https://doi.org/10.15479/AT-ISTA-22694</a>"},"publisher_comment":"For open access purposes, the author has applied a CC BY public copyright\r\nlicense to any author-accepted manuscript version arising from this submission."},{"article_type":"original","intvolume":"      2026","corr_author":"1","external_id":{"arxiv":["2507.09392"]},"citation":{"chicago":"Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/imrn/rnag058\">https://doi.org/10.1093/imrn/rnag058</a>.","short":"J. Löwit, International Mathematics Research Notices 2026 (2026).","mla":"Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” <i>International Mathematics Research Notices</i>, vol. 2026, no. 7, rnag058, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/imrn/rnag058\">10.1093/imrn/rnag058</a>.","ista":"Löwit J. 2026. Equivariant localizing invariants of simple varieties. International Mathematics Research Notices. 2026(7), rnag058.","ieee":"J. Löwit, “Equivariant localizing invariants of simple varieties,” <i>International Mathematics Research Notices</i>, vol. 2026, no. 7. Oxford University Press, 2026.","apa":"Löwit, J. (2026). Equivariant localizing invariants of simple varieties. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rnag058\">https://doi.org/10.1093/imrn/rnag058</a>","ama":"Löwit J. Equivariant localizing invariants of simple varieties. <i>International Mathematics Research Notices</i>. 2026;2026(7). doi:<a href=\"https://doi.org/10.1093/imrn/rnag058\">10.1093/imrn/rnag058</a>"},"fulldoi":"https://doi.org/10.1093/imrn/rnag058","date_created":"2026-04-19T22:07:48Z","publisher":"Oxford University Press","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2026-08-26T06:53:54Z","language":[{"iso":"eng"}],"department":[{"_id":"TaHa"}],"arxiv":1,"oa":1,"author":[{"last_name":"Löwit","full_name":"Löwit, Jakub","first_name":"Jakub","id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0"}],"ddc":["510"],"day":"01","doi":"10.1093/imrn/rnag058","issue":"7","file_date_updated":"2026-05-06T06:35:05Z","volume":2026,"publication":"International Mathematics Research Notices","abstract":[{"text":"We define a certain class of simple varieties over a field k by a constructive recipe and show how to control their (equivariant) truncating invariants. Consequently, we prove that on simple varieties: (i) if k = k and char k = p, the p-adic cyclotomic trace is an equivalence; (ii) if k = Q, the Goodwillie–Jones trace is an isomorphism in degree zero; (iii) we can control homotopy invariant K-theory KH, which is equivariantly formal and determined by its topological counterparts. Simple varieties are quite special, but encompass important singular examples appearing in geometric representation theory. We, in particular, show that both finite and affine Schubert varieties for GLn lie in this class, so all the above results hold for them. ","lang":"eng"}],"oa_version":"Published Version","PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","project":[{"grant_number":"27004","name":"Arithmetic, geometry, topology and representation theory arising from the affine Grassmannian","_id":"901e2a43-16d5-11f0-9cad-9cead34748d6"}],"month":"04","quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","has_accepted_license":"1","publication_identifier":{"eissn":["1687-0247"],"issn":["1073-7928"]},"article_number":"rnag058","_id":"21751","file":[{"access_level":"open_access","date_updated":"2026-05-06T06:35:05Z","file_id":"21803","file_name":"2026_IMRN_Loewit.pdf","checksum":"306f4567b7b2dcf38e23f7b55a27514e","file_size":1663246,"creator":"dernst","content_type":"application/pdf","date_created":"2026-05-06T06:35:05Z","relation":"main_file","success":1}],"year":"2026","type":"journal_article","related_material":{"record":[{"status":"public","id":"22694","relation":"dissertation_contains"}]},"status":"public","date_published":"2026-04-01T00:00:00Z","acknowledgement":"This work was supported by a DOC Fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (ISTA) and by an Erasmus+ staff mobility training. It took place during the author’s visit to Laboratoire de Mathématiques d’Orsay in the course of his PhD at the Institute of Science and Technology Austria. First and foremost, I would like to thank Matthew Morrow for discussions, explanations and ideas without which this work would not have been carried out. I would further like to thank Brian Conrad for providing an amazing reference on projective cones in appropriate generality, to Vova Sosnilo for carefully discussing – among other things – the derived nilinvariance for quotients by any linearly reductive group, and to Adeel Khan, Timo Richarz, Matthias Wendt and Xinwen Zhu for helpful conversations\r\nabout the results. I would moreover like to thank the referee for the very useful comments.","OA_type":"hybrid","title":"Equivariant localizing invariants of simple varieties","OA_place":"publisher","scopus_import":"1"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"no","publication_status":"epub_ahead","project":[{"name":"Geometry of the tip of the global nilpotent cone","_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3","grant_number":"P35847"}],"month":"03","quality_controlled":"1","has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","publication_identifier":{"issn":["1431-0635"],"eissn":["1431-0643"]},"day":"26","doi":"10.4171/dm/1064","publication":"Documenta Mathematica","abstract":[{"text":"We study torus-equivariant algebraic K-theory of affine Schubert varieties in the perfect affine Grassmannians over Fp. We further compare it to the torus-equivariant Hochschild homology of perfect complexes, which has a geometric description in terms of global functions on certain fixed-point schemes. We prove that Fp-linearly, this comparison is an isomorphism. Our approach is quite constructive, resulting in new computations of these K-theory rings. We establish various structural results for equivariant perfect algebraic K-theory on the way; we believe these are of independent interest.","lang":"eng"}],"das_tickbox":"0","PlanS_conform":"1","oa_version":"Published Version","OA_type":"hybrid","keyword":["equivariant algebraic K-theory","perfection in positive characteristic","affine Grassmannian","affine Schubert varieties","Dennis trace map","equivariant Hochschild homology","fixed-point schemes","toric varieties"],"title":"Equivariant K-theory, affine Grassmannian and perfection","OA_place":"publisher","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.4171/DM/1064","open_access":"1"}],"_id":"22693","year":"2026","type":"journal_article","related_material":{"record":[{"relation":"dissertation_contains","id":"22694","status":"public"}]},"status":"public","date_published":"2026-03-26T00:00:00Z","acknowledgement":"I would like to thank the following people for fruitful discussions,\r\nhelpful sanity checks or comments on previous drafts: Roman Bezrukavnikov, Jens Niklas Eberhardt, Mischa Elkner, Tamás Hausel, Andres Fernandez Herrero, Adeel Khan,\r\nBernhard Köck, Andrei Konovalov, Quoc Ho, Mirko Mauri, Matthew Morrow, Charanya\r\nRavi, Kamil Rychlewicz, Shyiu Shen, Vladimir Sosnilo, Georg Tamme, Xinwen Zhu. I\r\nwould further like to thank Marc Hoyois and the anonymous referee for spotting an error\r\nin a previous version.\r\nThis work was done during author’s PhD at the Institute of Science and Technology Austria (ISTA). It was funded by a DOC Fellowship of the Austrian Academy\r\nof Sciences and by the Austrian Science Fund (FWF) 10.55776/P35847. For open access\r\npurposes, the author has applied a CC BY public copyright license to any author-accepted\r\nmanuscript version arising from this submission.","date_created":"2026-08-12T13:29:17Z","publisher":"EMS Press","mathsc":["19E08","19L47","20G44","14G17","19D55","14F43","14L30","14D24","14M25"],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"original","external_id":{"arxiv":["2409.18925"]},"corr_author":"1","citation":{"ieee":"J. Löwit, “Equivariant K-theory, affine Grassmannian and perfection,” <i>Documenta Mathematica</i>. EMS Press, 2026.","ista":"Löwit J. 2026. Equivariant K-theory, affine Grassmannian and perfection. Documenta Mathematica.","ama":"Löwit J. Equivariant K-theory, affine Grassmannian and perfection. <i>Documenta Mathematica</i>. 2026. doi:<a href=\"https://doi.org/10.4171/dm/1064\">10.4171/dm/1064</a>","apa":"Löwit, J. (2026). Equivariant K-theory, affine Grassmannian and perfection. <i>Documenta Mathematica</i>. EMS Press. <a href=\"https://doi.org/10.4171/dm/1064\">https://doi.org/10.4171/dm/1064</a>","short":"J. Löwit, Documenta Mathematica (2026).","chicago":"Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.” <i>Documenta Mathematica</i>. EMS Press, 2026. <a href=\"https://doi.org/10.4171/dm/1064\">https://doi.org/10.4171/dm/1064</a>.","mla":"Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.” <i>Documenta Mathematica</i>, EMS Press, 2026, doi:<a href=\"https://doi.org/10.4171/dm/1064\">10.4171/dm/1064</a>."},"fulldoi":"https://doi.org/10.4171/dm/1064","oa":1,"arxiv":1,"author":[{"id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0","first_name":"Jakub","full_name":"Löwit, Jakub","last_name":"Löwit"}],"ddc":["500"],"researchdata_availability":"no","date_updated":"2026-08-26T06:53:54Z","department":[{"_id":"GradSch"},{"_id":"TaHa"}],"language":[{"iso":"eng"}]}]