[{"author":[{"full_name":"Steens, Jurre A.","first_name":"Jurre A.","last_name":"Steens"},{"last_name":"Zhu","first_name":"Yifan","full_name":"Zhu, Yifan"},{"first_name":"David W.","last_name":"Taylor","full_name":"Taylor, David W."},{"last_name":"Bravo","orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly","full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e"},{"last_name":"Prinsen","first_name":"Stijn H. P.","full_name":"Prinsen, Stijn H. P."},{"last_name":"Schoen","first_name":"Cor D.","full_name":"Schoen, Cor D."},{"full_name":"Keijser, Bart J. F.","first_name":"Bart J. F.","last_name":"Keijser"},{"full_name":"Ossendrijver, Michel","last_name":"Ossendrijver","first_name":"Michel"},{"first_name":"L. Marije","last_name":"Hofstra","full_name":"Hofstra, L. Marije"},{"last_name":"Brouns","first_name":"Stan J. J.","full_name":"Brouns, Stan J. J."},{"full_name":"Shinkai, Akeo","first_name":"Akeo","last_name":"Shinkai"},{"full_name":"van der Oost, John","first_name":"John","last_name":"van der Oost"},{"full_name":"Staals, Raymond H. J.","first_name":"Raymond H. J.","last_name":"Staals"}],"title":"SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation","date_updated":"2024-06-04T06:11:54Z","day":"19","publication_identifier":{"issn":["2041-1723"]},"article_type":"original","external_id":{"pmid":["34413302"]},"oa_version":"Published Version","quality_controlled":"1","main_file_link":[{"url":"https://doi.org/10.1038/s41467-021-25337-5","open_access":"1"}],"_id":"15137","extern":"1","volume":12,"scopus_import":"1","doi":"10.1038/s41467-021-25337-5","citation":{"apa":"Steens, J. A., Zhu, Y., Taylor, D. W., Bravo, J. P. K., Prinsen, S. H. P., Schoen, C. D., … Staals, R. H. J. (2021). SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-021-25337-5\">https://doi.org/10.1038/s41467-021-25337-5</a>","ama":"Steens JA, Zhu Y, Taylor DW, et al. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. <i>Nature Communications</i>. 2021;12. doi:<a href=\"https://doi.org/10.1038/s41467-021-25337-5\">10.1038/s41467-021-25337-5</a>","ista":"Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF, Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ. 2021. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nature Communications. 12, 5033.","mla":"Steens, Jurre A., et al. “SCOPE Enables Type III CRISPR-Cas Diagnostics Using Flexible Targeting and Stringent CARF Ribonuclease Activation.” <i>Nature Communications</i>, vol. 12, 5033, Springer Nature, 2021, doi:<a href=\"https://doi.org/10.1038/s41467-021-25337-5\">10.1038/s41467-021-25337-5</a>.","ieee":"J. A. Steens <i>et al.</i>, “SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation,” <i>Nature Communications</i>, vol. 12. Springer Nature, 2021.","short":"J.A. Steens, Y. Zhu, D.W. Taylor, J.P.K. Bravo, S.H.P. Prinsen, C.D. Schoen, B.J.F. Keijser, M. Ossendrijver, L.M. Hofstra, S.J.J. Brouns, A. Shinkai, J. van der Oost, R.H.J. Staals, Nature Communications 12 (2021).","chicago":"Steens, Jurre A., Yifan Zhu, David W. Taylor, Jack Peter Kelly Bravo, Stijn H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, et al. “SCOPE Enables Type III CRISPR-Cas Diagnostics Using Flexible Targeting and Stringent CARF Ribonuclease Activation.” <i>Nature Communications</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41467-021-25337-5\">https://doi.org/10.1038/s41467-021-25337-5</a>."},"publication_status":"published","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"article_processing_charge":"Yes","year":"2021","date_published":"2021-08-19T00:00:00Z","article_number":"5033","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"type":"journal_article","status":"public","publication":"Nature Communications","month":"08","publisher":"Springer Nature","abstract":[{"text":"Characteristic properties of type III CRISPR-Cas systems include recognition of target RNA and the subsequent induction of a multifaceted immune response. This involves sequence-specific cleavage of the target RNA and production of cyclic oligoadenylate (cOA) molecules. Here we report that an exposed seed region at the 3′ end of the crRNA is essential for target RNA binding and cleavage, whereas cOA production requires base pairing at the 5′ end of the crRNA. Moreover, we uncover that the variation in the size and composition of type III complexes within a single host results in variable seed regions. This may prevent escape by invading genetic elements, while controlling cOA production tightly to prevent unnecessary damage to the host. Lastly, we use these findings to develop a new diagnostic tool, SCOPE, for the specific detection of SARS-CoV-2 from human nasal swab samples, revealing sensitivities in the atto-molar range.","lang":"eng"}],"date_created":"2024-03-20T10:42:33Z","pmid":1,"intvolume":"        12","language":[{"iso":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e107711","date_published":"2021-11-02T00:00:00Z","article_processing_charge":"Yes","year":"2021","keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","Molecular Biology","General Neuroscience"],"publication_status":"published","type":"journal_article","oa":1,"month":"11","status":"public","publication":"The EMBO Journal","issue":"21","language":[{"iso":"eng"}],"intvolume":"        40","abstract":[{"text":"RNA viruses induce the formation of subcellular organelles that provide microenvironments conducive to their replication. Here we show that replication factories of rotaviruses represent protein‐RNA condensates that are formed via liquid–liquid phase separation of the viroplasm‐forming proteins NSP5 and rotavirus RNA chaperone NSP2. Upon mixing, these proteins readily form condensates at physiologically relevant low micromolar concentrations achieved in the cytoplasm of virus‐infected cells. Early infection stage condensates could be reversibly dissolved by 1,6‐hexanediol, as well as propylene glycol that released rotavirus transcripts from these condensates. During the early stages of infection, propylene glycol treatments reduced viral replication and phosphorylation of the condensate‐forming protein NSP5. During late infection, these condensates exhibited altered material properties and became resistant to propylene glycol, coinciding with hyperphosphorylation of NSP5. Some aspects of the assembly of cytoplasmic rotavirus replication factories mirror the formation of other ribonucleoprotein granules. Such viral RNA‐rich condensates that support replication of multi‐segmented genomes represent an attractive target for developing novel therapeutic approaches.","lang":"eng"}],"pmid":1,"date_created":"2024-03-20T10:42:39Z","publisher":"Embo Press","date_updated":"2024-06-04T06:08:16Z","title":"Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses","author":[{"full_name":"Geiger, Florian","last_name":"Geiger","first_name":"Florian"},{"full_name":"Acker, Julia","first_name":"Julia","last_name":"Acker"},{"last_name":"Papa","first_name":"Guido","full_name":"Papa, Guido"},{"full_name":"Wang, Xinyu","first_name":"Xinyu","last_name":"Wang"},{"full_name":"Arter, William E","last_name":"Arter","first_name":"William E"},{"last_name":"Saar","first_name":"Kadi L","full_name":"Saar, Kadi L"},{"first_name":"Nadia A","last_name":"Erkamp","full_name":"Erkamp, Nadia A"},{"full_name":"Qi, Runzhang","last_name":"Qi","first_name":"Runzhang"},{"first_name":"Jack Peter Kelly","last_name":"Bravo","orcid":"0000-0003-0456-0753","full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e"},{"full_name":"Strauss, Sebastian","first_name":"Sebastian","last_name":"Strauss"},{"full_name":"Krainer, Georg","last_name":"Krainer","first_name":"Georg"},{"first_name":"Oscar R","last_name":"Burrone","full_name":"Burrone, Oscar R"},{"full_name":"Jungmann, Ralf","first_name":"Ralf","last_name":"Jungmann"},{"full_name":"Knowles, Tuomas PJ","first_name":"Tuomas PJ","last_name":"Knowles"},{"full_name":"Engelke, Hanna","first_name":"Hanna","last_name":"Engelke"},{"full_name":"Borodavka, Alexander","first_name":"Alexander","last_name":"Borodavka"}],"external_id":{"pmid":["34524703"]},"article_type":"original","publication_identifier":{"issn":["0261-4189"],"eissn":["1460-2075"]},"day":"02","extern":"1","_id":"15138","main_file_link":[{"url":"https://doi.org/10.15252/embj.2021107711","open_access":"1"}],"quality_controlled":"1","oa_version":"Published Version","citation":{"mla":"Geiger, Florian, et al. “Liquid–Liquid Phase Separation Underpins the Formation of Replication Factories in Rotaviruses.” <i>The EMBO Journal</i>, vol. 40, no. 21, e107711, Embo Press, 2021, doi:<a href=\"https://doi.org/10.15252/embj.2021107711\">10.15252/embj.2021107711</a>.","ieee":"F. Geiger <i>et al.</i>, “Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses,” <i>The EMBO Journal</i>, vol. 40, no. 21. Embo Press, 2021.","apa":"Geiger, F., Acker, J., Papa, G., Wang, X., Arter, W. E., Saar, K. L., … Borodavka, A. (2021). Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses. <i>The EMBO Journal</i>. Embo Press. <a href=\"https://doi.org/10.15252/embj.2021107711\">https://doi.org/10.15252/embj.2021107711</a>","ista":"Geiger F, Acker J, Papa G, Wang X, Arter WE, Saar KL, Erkamp NA, Qi R, Bravo JPK, Strauss S, Krainer G, Burrone OR, Jungmann R, Knowles TP, Engelke H, Borodavka A. 2021. Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses. The EMBO Journal. 40(21), e107711.","ama":"Geiger F, Acker J, Papa G, et al. Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses. <i>The EMBO Journal</i>. 2021;40(21). doi:<a href=\"https://doi.org/10.15252/embj.2021107711\">10.15252/embj.2021107711</a>","chicago":"Geiger, Florian, Julia Acker, Guido Papa, Xinyu Wang, William E Arter, Kadi L Saar, Nadia A Erkamp, et al. “Liquid–Liquid Phase Separation Underpins the Formation of Replication Factories in Rotaviruses.” <i>The EMBO Journal</i>. Embo Press, 2021. <a href=\"https://doi.org/10.15252/embj.2021107711\">https://doi.org/10.15252/embj.2021107711</a>.","short":"F. Geiger, J. Acker, G. Papa, X. Wang, W.E. Arter, K.L. Saar, N.A. Erkamp, R. Qi, J.P.K. Bravo, S. Strauss, G. Krainer, O.R. Burrone, R. Jungmann, T.P. Knowles, H. Engelke, A. Borodavka, The EMBO Journal 40 (2021)."},"doi":"10.15252/embj.2021107711","scopus_import":"1","volume":40},{"article_type":"original","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"day":"06","external_id":{"pmid":["34615715"]},"author":[{"first_name":"Jack Peter Kelly","last_name":"Bravo","orcid":"0000-0003-0456-0753","full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e"},{"last_name":"Bartnik","first_name":"Kira","full_name":"Bartnik, Kira"},{"full_name":"Venditti, Luca","last_name":"Venditti","first_name":"Luca"},{"first_name":"Julia","last_name":"Acker","full_name":"Acker, Julia"},{"last_name":"Gail","first_name":"Emma H.","full_name":"Gail, Emma H."},{"first_name":"Alice","last_name":"Colyer","full_name":"Colyer, Alice"},{"full_name":"Davidovich, Chen","first_name":"Chen","last_name":"Davidovich"},{"full_name":"Lamb, Don C.","last_name":"Lamb","first_name":"Don C."},{"full_name":"Tuma, Roman","first_name":"Roman","last_name":"Tuma"},{"last_name":"Calabrese","first_name":"Antonio N.","full_name":"Calabrese, Antonio N."},{"first_name":"Alexander","last_name":"Borodavka","full_name":"Borodavka, Alexander"}],"date_updated":"2024-06-04T06:04:07Z","title":"Structural basis of rotavirus RNA chaperone displacement and RNA annealing","volume":118,"scopus_import":"1","doi":"10.1073/pnas.2100198118","citation":{"chicago":"Bravo, Jack Peter Kelly, Kira Bartnik, Luca Venditti, Julia Acker, Emma H. Gail, Alice Colyer, Chen Davidovich, et al. “Structural Basis of Rotavirus RNA Chaperone Displacement and RNA Annealing.” <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences, 2021. <a href=\"https://doi.org/10.1073/pnas.2100198118\">https://doi.org/10.1073/pnas.2100198118</a>.","short":"J.P.K. Bravo, K. Bartnik, L. Venditti, J. Acker, E.H. Gail, A. Colyer, C. Davidovich, D.C. Lamb, R. Tuma, A.N. Calabrese, A. Borodavka, Proceedings of the National Academy of Sciences 118 (2021).","ieee":"J. P. K. Bravo <i>et al.</i>, “Structural basis of rotavirus RNA chaperone displacement and RNA annealing,” <i>Proceedings of the National Academy of Sciences</i>, vol. 118, no. 41. Proceedings of the National Academy of Sciences, 2021.","mla":"Bravo, Jack Peter Kelly, et al. “Structural Basis of Rotavirus RNA Chaperone Displacement and RNA Annealing.” <i>Proceedings of the National Academy of Sciences</i>, vol. 118, no. 41, e2100198118, Proceedings of the National Academy of Sciences, 2021, doi:<a href=\"https://doi.org/10.1073/pnas.2100198118\">10.1073/pnas.2100198118</a>.","ama":"Bravo JPK, Bartnik K, Venditti L, et al. Structural basis of rotavirus RNA chaperone displacement and RNA annealing. <i>Proceedings of the National Academy of Sciences</i>. 2021;118(41). doi:<a href=\"https://doi.org/10.1073/pnas.2100198118\">10.1073/pnas.2100198118</a>","ista":"Bravo JPK, Bartnik K, Venditti L, Acker J, Gail EH, Colyer A, Davidovich C, Lamb DC, Tuma R, Calabrese AN, Borodavka A. 2021. Structural basis of rotavirus RNA chaperone displacement and RNA annealing. Proceedings of the National Academy of Sciences. 118(41), e2100198118.","apa":"Bravo, J. P. K., Bartnik, K., Venditti, L., Acker, J., Gail, E. H., Colyer, A., … Borodavka, A. (2021). Structural basis of rotavirus RNA chaperone displacement and RNA annealing. <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2100198118\">https://doi.org/10.1073/pnas.2100198118</a>"},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1073/pnas.2100198118"}],"quality_controlled":"1","oa_version":"Published Version","_id":"15139","extern":"1","oa":1,"type":"journal_article","year":"2021","article_processing_charge":"No","publication_status":"published","article_number":"e2100198118","date_published":"2021-10-06T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Proceedings of the National Academy of Sciences","pmid":1,"date_created":"2024-03-20T10:42:45Z","abstract":[{"text":"Rotavirus genomes are distributed between 11 distinct RNA molecules, all of which must be selectively copackaged during virus assembly. This likely occurs through sequence-specific RNA interactions facilitated by the RNA chaperone NSP2. Here, we report that NSP2 autoregulates its chaperone activity through its C-terminal region (CTR) that promotes RNA–RNA interactions by limiting its helix-unwinding activity. Unexpectedly, structural proteomics data revealed that the CTR does not directly interact with RNA, while accelerating RNA release from NSP2. Cryo–electron microscopy reconstructions of an NSP2–RNA complex reveal a highly conserved acidic patch on the CTR, which is poised toward the bound RNA. Virus replication was abrogated by charge-disrupting mutations within the acidic patch but completely restored by charge-preserving mutations. Mechanistic similarities between NSP2 and the unrelated bacterial RNA chaperone Hfq suggest that accelerating RNA dissociation while promoting intermolecular RNA interactions may be a widespread strategy of RNA chaperone recycling.","lang":"eng"}],"intvolume":"       118","language":[{"iso":"eng"}],"issue":"41","month":"10","publication":"Proceedings of the National Academy of Sciences","status":"public"},{"author":[{"full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","last_name":"Bravo","orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly"},{"last_name":"Dangerfield","first_name":"Tyler L.","full_name":"Dangerfield, Tyler L."},{"full_name":"Taylor, David W.","last_name":"Taylor","first_name":"David W."},{"full_name":"Johnson, Kenneth A.","last_name":"Johnson","first_name":"Kenneth A."}],"title":"Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication","date_updated":"2024-06-04T06:00:56Z","day":"01","publication_identifier":{"issn":["1097-2765"]},"article_type":"original","external_id":{"pmid":["33631104"]},"extern":"1","_id":"15140","oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2020.12.14.422718 "}],"scopus_import":"1","volume":81,"citation":{"short":"J.P.K. Bravo, T.L. Dangerfield, D.W. Taylor, K.A. Johnson, Molecular Cell 81 (2021) 1548–1552.e4.","chicago":"Bravo, Jack Peter Kelly, Tyler L. Dangerfield, David W. Taylor, and Kenneth A. Johnson. “Remdesivir Is a Delayed Translocation Inhibitor of SARS-CoV-2 Replication.” <i>Molecular Cell</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.molcel.2021.01.035\">https://doi.org/10.1016/j.molcel.2021.01.035</a>.","ista":"Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA. 2021. Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. Molecular Cell. 81(7), 1548–1552.e4.","apa":"Bravo, J. P. K., Dangerfield, T. L., Taylor, D. W., &#38; Johnson, K. A. (2021). Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2021.01.035\">https://doi.org/10.1016/j.molcel.2021.01.035</a>","ama":"Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA. Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. <i>Molecular Cell</i>. 2021;81(7):1548-1552.e4. doi:<a href=\"https://doi.org/10.1016/j.molcel.2021.01.035\">10.1016/j.molcel.2021.01.035</a>","mla":"Bravo, Jack Peter Kelly, et al. “Remdesivir Is a Delayed Translocation Inhibitor of SARS-CoV-2 Replication.” <i>Molecular Cell</i>, vol. 81, no. 7, Elsevier, 2021, p. 1548–1552.e4, doi:<a href=\"https://doi.org/10.1016/j.molcel.2021.01.035\">10.1016/j.molcel.2021.01.035</a>.","ieee":"J. P. K. Bravo, T. L. Dangerfield, D. W. Taylor, and K. A. Johnson, “Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication,” <i>Molecular Cell</i>, vol. 81, no. 7. Elsevier, p. 1548–1552.e4, 2021."},"doi":"10.1016/j.molcel.2021.01.035","publication_status":"published","article_processing_charge":"No","year":"2021","keyword":["Cell Biology","Molecular Biology"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-04-01T00:00:00Z","page":"1548-1552.e4","type":"journal_article","oa":1,"issue":"7","publication":"Molecular Cell","status":"public","month":"04","date_created":"2024-03-20T10:42:53Z","abstract":[{"text":"Remdesivir is a nucleoside analog approved by the US FDA for treatment of COVID-19. Here, we present a 3.9-Å-resolution cryo-EM reconstruction of a remdesivir-stalled RNA-dependent RNA polymerase complex, revealing full incorporation of 3 copies of remdesivir monophosphate (RMP) and a partially incorporated fourth RMP in the active site. The structure reveals that RMP blocks RNA translocation after incorporation of 3 bases following RMP, resulting in delayed chain termination, which can guide the rational design of improved antiviral drugs.","lang":"eng"}],"pmid":1,"publisher":"Elsevier","language":[{"iso":"eng"}],"intvolume":"        81"},{"external_id":{"pmid":["33733066"]},"day":"19","publication_identifier":{"issn":["2589-0042"]},"article_type":"original","title":"Structure of a type IV CRISPR-Cas ribonucleoprotein complex","date_updated":"2024-06-04T05:56:45Z","author":[{"full_name":"Zhou, Yi","last_name":"Zhou","first_name":"Yi"},{"last_name":"Bravo","orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly","full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e"},{"first_name":"Hannah N.","last_name":"Taylor","full_name":"Taylor, Hannah N."},{"full_name":"Steens, Jurre A.","last_name":"Steens","first_name":"Jurre A."},{"full_name":"Jackson, Ryan N.","last_name":"Jackson","first_name":"Ryan N."},{"full_name":"Staals, Raymond H.J.","last_name":"Staals","first_name":"Raymond H.J."},{"last_name":"Taylor","first_name":"David W.","full_name":"Taylor, David W."}],"citation":{"ieee":"Y. Zhou <i>et al.</i>, “Structure of a type IV CRISPR-Cas ribonucleoprotein complex,” <i>iScience</i>, vol. 24, no. 3. Elsevier, 2021.","mla":"Zhou, Yi, et al. “Structure of a Type IV CRISPR-Cas Ribonucleoprotein Complex.” <i>IScience</i>, vol. 24, no. 3, 102201, Elsevier, 2021, doi:<a href=\"https://doi.org/10.1016/j.isci.2021.102201\">10.1016/j.isci.2021.102201</a>.","ama":"Zhou Y, Bravo JPK, Taylor HN, et al. Structure of a type IV CRISPR-Cas ribonucleoprotein complex. <i>iScience</i>. 2021;24(3). doi:<a href=\"https://doi.org/10.1016/j.isci.2021.102201\">10.1016/j.isci.2021.102201</a>","apa":"Zhou, Y., Bravo, J. P. K., Taylor, H. N., Steens, J. A., Jackson, R. N., Staals, R. H. J., &#38; Taylor, D. W. (2021). Structure of a type IV CRISPR-Cas ribonucleoprotein complex. <i>IScience</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.isci.2021.102201\">https://doi.org/10.1016/j.isci.2021.102201</a>","ista":"Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN, Staals RHJ, Taylor DW. 2021. Structure of a type IV CRISPR-Cas ribonucleoprotein complex. iScience. 24(3), 102201.","chicago":"Zhou, Yi, Jack Peter Kelly Bravo, Hannah N. Taylor, Jurre A. Steens, Ryan N. Jackson, Raymond H.J. Staals, and David W. Taylor. “Structure of a Type IV CRISPR-Cas Ribonucleoprotein Complex.” <i>IScience</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.isci.2021.102201\">https://doi.org/10.1016/j.isci.2021.102201</a>.","short":"Y. Zhou, J.P.K. Bravo, H.N. Taylor, J.A. Steens, R.N. Jackson, R.H.J. Staals, D.W. Taylor, IScience 24 (2021)."},"doi":"10.1016/j.isci.2021.102201","volume":24,"quality_controlled":"1","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.1016/j.isci.2021.102201","open_access":"1"}],"extern":"1","_id":"15141","oa":1,"type":"journal_article","date_published":"2021-03-19T00:00:00Z","article_number":"102201","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","keyword":["Multidisciplinary"],"article_processing_charge":"Yes (in subscription journal)","year":"2021","intvolume":"        24","language":[{"iso":"eng"}],"publisher":"Elsevier","date_created":"2024-03-20T10:43:00Z","pmid":1,"abstract":[{"text":"We reveal the cryo-electron microscopy structure of a type IV-B CRISPR ribonucleoprotein (RNP) complex (Csf) at 3.9-Å resolution. The complex best resembles the type III-A CRISPR Csm effector complex, consisting of a Cas7-like (Csf2) filament intertwined with a small subunit (Cas11) filament, but the complex lacks subunits for RNA processing and target DNA cleavage. Surprisingly, instead of assembling around a CRISPR-derived RNA (crRNA), the complex assembles upon heterogeneous RNA of a regular length arranged in a pseudo-A-form configuration. These findings provide a high-resolution glimpse into the assembly and function of enigmatic type IV CRISPR systems, expanding our understanding of class I CRISPR-Cas system architecture, and suggesting a function for type IV-B RNPs that may be distinct from other class 1 CRISPR-associated systems.","lang":"eng"}],"month":"03","status":"public","publication":"iScience","issue":"3"},{"_id":"15150","extern":"1","publication":"Nature","month":"08","oa_version":"None","status":"public","quality_controlled":"1","date_created":"2024-03-21T07:53:48Z","abstract":[{"lang":"eng","text":"The majority of gene transcripts generated by RNA polymerase II in mammalian genomes initiate at CpG island (CGI) promoters1,2, yet our understanding of their regulation remains limited. This is in part due to the incomplete information that we have on transcription factors, their DNA-binding motifs and which genomic binding sites are functional in any given cell type3,4,5. In addition, there are orphan motifs without known binders, such as the CGCG element, which is associated with highly expressed genes across human tissues and enriched near the transcription start site of a subset of CGI promoters6,7,8. Here we combine single-molecule footprinting with interaction proteomics to identify BTG3-associated nuclear protein (BANP) as the transcription factor that binds this element in the mouse and human genome. We show that BANP is a strong CGI activator that controls essential metabolic genes in pluripotent stem and terminally differentiated neuronal cells. BANP binding is repelled by DNA methylation of its motif in vitro and in vivo, which epigenetically restricts most binding to CGIs and accounts for differential binding at aberrantly methylated CGI promoters in cancer cells. Upon binding to an unmethylated motif, BANP opens chromatin and phases nucleosomes. These findings establish BANP as a critical activator of a set of essential genes and suggest a model in which the activity of CGI promoters relies on methylation-sensitive transcription factors that are capable of chromatin opening."}],"scopus_import":"1","volume":596,"publisher":"Springer Nature","language":[{"iso":"eng"}],"intvolume":"       596","citation":{"mla":"Grand, Ralph S., et al. “BANP Opens Chromatin and Activates CpG-Island-Regulated Genes.” <i>Nature</i>, vol. 596, Springer Nature, 2021, pp. 133–37, doi:<a href=\"https://doi.org/10.1038/s41586-021-03689-8\">10.1038/s41586-021-03689-8</a>.","ieee":"R. S. Grand <i>et al.</i>, “BANP opens chromatin and activates CpG-island-regulated genes,” <i>Nature</i>, vol. 596. Springer Nature, pp. 133–137, 2021.","ista":"Grand RS, Burger L, Gräwe C, Michael AK, Isbel L, Hess D, Hoerner L, Iesmantavicius V, Durdu S, Pregnolato M, Krebs AR, Smallwood SA, Thomä N, Vermeulen M, Schübeler D. 2021. BANP opens chromatin and activates CpG-island-regulated genes. Nature. 596, 133–137.","ama":"Grand RS, Burger L, Gräwe C, et al. BANP opens chromatin and activates CpG-island-regulated genes. <i>Nature</i>. 2021;596:133-137. doi:<a href=\"https://doi.org/10.1038/s41586-021-03689-8\">10.1038/s41586-021-03689-8</a>","apa":"Grand, R. S., Burger, L., Gräwe, C., Michael, A. K., Isbel, L., Hess, D., … Schübeler, D. (2021). BANP opens chromatin and activates CpG-island-regulated genes. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-021-03689-8\">https://doi.org/10.1038/s41586-021-03689-8</a>","chicago":"Grand, Ralph S., Lukas Burger, Cathrin Gräwe, Alicia K. Michael, Luke Isbel, Daniel Hess, Leslie Hoerner, et al. “BANP Opens Chromatin and Activates CpG-Island-Regulated Genes.” <i>Nature</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41586-021-03689-8\">https://doi.org/10.1038/s41586-021-03689-8</a>.","short":"R.S. Grand, L. Burger, C. Gräwe, A.K. Michael, L. Isbel, D. Hess, L. Hoerner, V. Iesmantavicius, S. Durdu, M. Pregnolato, A.R. Krebs, S.A. Smallwood, N. Thomä, M. Vermeulen, D. Schübeler, Nature 596 (2021) 133–137."},"doi":"10.1038/s41586-021-03689-8","article_processing_charge":"No","year":"2021","publication_status":"published","author":[{"full_name":"Grand, Ralph S.","first_name":"Ralph S.","last_name":"Grand"},{"last_name":"Burger","first_name":"Lukas","full_name":"Burger, Lukas"},{"full_name":"Gräwe, Cathrin","first_name":"Cathrin","last_name":"Gräwe"},{"first_name":"Alicia","last_name":"Michael","orcid":"0000-0002-6080-839X","full_name":"Michael, Alicia","id":"6437c950-2a03-11ee-914d-d6476dd7b75c"},{"last_name":"Isbel","first_name":"Luke","full_name":"Isbel, Luke"},{"last_name":"Hess","first_name":"Daniel","full_name":"Hess, Daniel"},{"first_name":"Leslie","last_name":"Hoerner","full_name":"Hoerner, Leslie"},{"last_name":"Iesmantavicius","first_name":"Vytautas","full_name":"Iesmantavicius, Vytautas"},{"full_name":"Durdu, Sevi","last_name":"Durdu","first_name":"Sevi"},{"full_name":"Pregnolato, Marco","first_name":"Marco","last_name":"Pregnolato"},{"last_name":"Krebs","first_name":"Arnaud R.","full_name":"Krebs, Arnaud R."},{"last_name":"Smallwood","first_name":"Sébastien A.","full_name":"Smallwood, Sébastien A."},{"first_name":"Nicolas","last_name":"Thomä","full_name":"Thomä, Nicolas"},{"full_name":"Vermeulen, Michiel","last_name":"Vermeulen","first_name":"Michiel"},{"first_name":"Dirk","last_name":"Schübeler","full_name":"Schübeler, Dirk"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2024-03-25T12:34:31Z","date_published":"2021-08-05T00:00:00Z","title":"BANP opens chromatin and activates CpG-island-regulated genes","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"article_type":"original","day":"05","page":"133-137","type":"journal_article"},{"quality_controlled":"1","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.1016/j.cell.2021.05.029","open_access":"1"}],"extern":"1","_id":"15151","citation":{"short":"A.K. Michael, N.H. Thomä, Cell 184 (2021) 3599–3611.","chicago":"Michael, Alicia K., and Nicolas H. Thomä. “Reading the Chromatinized Genome.” <i>Cell</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.cell.2021.05.029\">https://doi.org/10.1016/j.cell.2021.05.029</a>.","apa":"Michael, A. K., &#38; Thomä, N. H. (2021). Reading the chromatinized genome. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2021.05.029\">https://doi.org/10.1016/j.cell.2021.05.029</a>","ista":"Michael AK, Thomä NH. 2021. Reading the chromatinized genome. Cell. 184(14), 3599–3611.","ama":"Michael AK, Thomä NH. Reading the chromatinized genome. <i>Cell</i>. 2021;184(14):3599-3611. doi:<a href=\"https://doi.org/10.1016/j.cell.2021.05.029\">10.1016/j.cell.2021.05.029</a>","ieee":"A. K. Michael and N. H. Thomä, “Reading the chromatinized genome,” <i>Cell</i>, vol. 184, no. 14. Elsevier, pp. 3599–3611, 2021.","mla":"Michael, Alicia K., and Nicolas H. Thomä. “Reading the Chromatinized Genome.” <i>Cell</i>, vol. 184, no. 14, Elsevier, 2021, pp. 3599–611, doi:<a href=\"https://doi.org/10.1016/j.cell.2021.05.029\">10.1016/j.cell.2021.05.029</a>."},"doi":"10.1016/j.cell.2021.05.029","volume":184,"scopus_import":"1","title":"Reading the chromatinized genome","date_updated":"2024-03-25T12:31:39Z","author":[{"id":"6437c950-2a03-11ee-914d-d6476dd7b75c","full_name":"Michael, Alicia","first_name":"Alicia","orcid":"0000-0002-6080-839X","last_name":"Michael"},{"last_name":"Thomä","first_name":"Nicolas H.","full_name":"Thomä, Nicolas H."}],"day":"08","publication_identifier":{"issn":["0092-8674"]},"article_type":"review","status":"public","month":"07","publication":"Cell","issue":"14","intvolume":"       184","language":[{"iso":"eng"}],"publisher":"Elsevier","abstract":[{"lang":"eng","text":"Eukaryotic DNA-binding proteins operate in the context of chromatin, where nucleosomes are the elementary building blocks. Nucleosomal DNA is wrapped around a histone core, thereby rendering a large fraction of the DNA surface inaccessible to DNA-binding proteins. Nevertheless, first responders in DNA repair and sequence-specific transcription factors bind DNA target sites obstructed by chromatin. While early studies examined protein binding to histone-free DNA, it is only now beginning to emerge how DNA sequences are interrogated on nucleosomes. These readout strategies range from the release of nucleosomal DNA from histones, to rotational/translation register shifts of the DNA motif, and nucleosome-specific DNA binding modes that differ from those observed on naked DNA. Since DNA motif engagement on nucleosomes strongly depends on position and orientation, we argue that motif location and nucleosome positioning co-determine protein access to DNA in transcription and DNA repair."}],"date_created":"2024-03-21T07:54:19Z","date_published":"2021-07-08T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","year":"2021","article_processing_charge":"No","keyword":["General Biochemistry","Genetics and Molecular Biology"],"oa":1,"type":"journal_article","page":"3599-3611"},{"oa":1,"type":"journal_article","year":"2021","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"article_processing_charge":"No","publication_status":"published","article_number":"120","date_published":"2021-10-21T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"American Astronomical Society","date_created":"2024-03-26T10:32:06Z","abstract":[{"text":"AT2019wey (SRGA J043520.9+552226, SRGE J043523.3+552234) is a transient first reported by the ATLAS optical survey in 2019 December. It rose to prominence upon detection, three months later, by the Spektrum-Roentgen-Gamma (SRG) mission in its first all-sky survey. X-ray observations reported in Yao et al. suggest that AT2019wey is a Galactic low-mass X-ray binary (LMXB) with a black hole (BH) or neutron star (NS) accretor. Here we present ultraviolet, optical, near-infrared, and radio observations of this object. We show that the companion is a short-period (P ≲ 16 hr) low-mass (<1 M⊙) star. We consider AT2019wey to be a candidate BH system since its locations on the Lradio–LX and Lopt–LX diagrams are closer to BH binaries than NS binaries. We demonstrate that from 2020 June to August, despite the more than 10 times brightening at radio and X-ray wavelengths, the optical luminosity of AT2019wey only increased by 1.3–1.4 times. We interpret the UV/optical emission before the brightening as thermal emission from a truncated disk in a hot accretion flow and the UV/optical emission after the brightening as reprocessing of the X-ray emission in the outer accretion disk. AT2019wey demonstrates that combining current wide-field optical surveys and SRG provides a way to discover the emerging population of short-period BH LMXB systems with faint X-ray outbursts.","lang":"eng"}],"intvolume":"       920","language":[{"iso":"eng"}],"issue":"2","month":"10","status":"public","publication":"The Astrophysical Journal","arxiv":1,"publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"article_type":"original","day":"21","external_id":{"arxiv":["2012.00169"]},"author":[{"full_name":"Yao, Yuhan","last_name":"Yao","first_name":"Yuhan"},{"full_name":"Kulkarni, S. R.","first_name":"S. R.","last_name":"Kulkarni"},{"first_name":"Kevin B.","last_name":"Burdge","full_name":"Burdge, Kevin B."},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria","first_name":"Ilaria","orcid":"0000-0002-4770-5388","last_name":"Caiazzo"},{"first_name":"Kishalay","last_name":"De","full_name":"De, Kishalay"},{"full_name":"Dong, Dillon","first_name":"Dillon","last_name":"Dong"},{"first_name":"C.","last_name":"Fremling","full_name":"Fremling, C."},{"first_name":"Mansi M.","last_name":"Kasliwal","full_name":"Kasliwal, Mansi M."},{"last_name":"Kupfer","first_name":"Thomas","full_name":"Kupfer, Thomas"},{"full_name":"van Roestel, Jan","first_name":"Jan","last_name":"van Roestel"},{"full_name":"Sollerman, Jesper","last_name":"Sollerman","first_name":"Jesper"},{"full_name":"Bagdasaryan, Ashot","first_name":"Ashot","last_name":"Bagdasaryan"},{"full_name":"Bellm, Eric C.","first_name":"Eric C.","last_name":"Bellm"},{"last_name":"Cenko","first_name":"S. Bradley","full_name":"Cenko, S. Bradley"},{"full_name":"Drake, Andrew J.","last_name":"Drake","first_name":"Andrew J."},{"full_name":"Duev, Dmitry A.","first_name":"Dmitry A.","last_name":"Duev"},{"first_name":"Matthew J.","last_name":"Graham","full_name":"Graham, Matthew J."},{"last_name":"Kaye","first_name":"Stephen","full_name":"Kaye, Stephen"},{"first_name":"Frank J.","last_name":"Masci","full_name":"Masci, Frank J."},{"full_name":"Miranda, Nicolas","last_name":"Miranda","first_name":"Nicolas"},{"full_name":"Prince, Thomas A.","last_name":"Prince","first_name":"Thomas A."},{"full_name":"Riddle, Reed","first_name":"Reed","last_name":"Riddle"},{"last_name":"Rusholme","first_name":"Ben","full_name":"Rusholme, Ben"},{"full_name":"Soumagnac, Maayane T.","first_name":"Maayane T.","last_name":"Soumagnac"}],"date_updated":"2024-04-02T07:28:22Z","title":"Multi-wavelength observations of AT2019wey: A new candidate black hole low-mass X-ray binary","volume":920,"scopus_import":"1","citation":{"mla":"Yao, Yuhan, et al. “Multi-Wavelength Observations of AT2019wey: A New Candidate Black Hole Low-Mass X-Ray Binary.” <i>The Astrophysical Journal</i>, vol. 920, no. 2, 120, American Astronomical Society, 2021, doi:<a href=\"https://doi.org/10.3847/1538-4357/ac15f9\">10.3847/1538-4357/ac15f9</a>.","ieee":"Y. Yao <i>et al.</i>, “Multi-wavelength observations of AT2019wey: A new candidate black hole low-mass X-ray binary,” <i>The Astrophysical Journal</i>, vol. 920, no. 2. American Astronomical Society, 2021.","ista":"Yao Y, Kulkarni SR, Burdge KB, Caiazzo I, De K, Dong D, Fremling C, Kasliwal MM, Kupfer T, van Roestel J, Sollerman J, Bagdasaryan A, Bellm EC, Cenko SB, Drake AJ, Duev DA, Graham MJ, Kaye S, Masci FJ, Miranda N, Prince TA, Riddle R, Rusholme B, Soumagnac MT. 2021. Multi-wavelength observations of AT2019wey: A new candidate black hole low-mass X-ray binary. The Astrophysical Journal. 920(2), 120.","ama":"Yao Y, Kulkarni SR, Burdge KB, et al. Multi-wavelength observations of AT2019wey: A new candidate black hole low-mass X-ray binary. <i>The Astrophysical Journal</i>. 2021;920(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ac15f9\">10.3847/1538-4357/ac15f9</a>","apa":"Yao, Y., Kulkarni, S. R., Burdge, K. B., Caiazzo, I., De, K., Dong, D., … Soumagnac, M. T. (2021). Multi-wavelength observations of AT2019wey: A new candidate black hole low-mass X-ray binary. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/ac15f9\">https://doi.org/10.3847/1538-4357/ac15f9</a>","chicago":"Yao, Yuhan, S. R. Kulkarni, Kevin B. Burdge, Ilaria Caiazzo, Kishalay De, Dillon Dong, C. Fremling, et al. “Multi-Wavelength Observations of AT2019wey: A New Candidate Black Hole Low-Mass X-Ray Binary.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2021. <a href=\"https://doi.org/10.3847/1538-4357/ac15f9\">https://doi.org/10.3847/1538-4357/ac15f9</a>.","short":"Y. Yao, S.R. Kulkarni, K.B. Burdge, I. Caiazzo, K. De, D. Dong, C. Fremling, M.M. Kasliwal, T. Kupfer, J. van Roestel, J. Sollerman, A. Bagdasaryan, E.C. Bellm, S.B. Cenko, A.J. Drake, D.A. Duev, M.J. Graham, S. Kaye, F.J. Masci, N. Miranda, T.A. Prince, R. Riddle, B. Rusholme, M.T. Soumagnac, The Astrophysical Journal 920 (2021)."},"doi":"10.3847/1538-4357/ac15f9","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2012.00169"}],"oa_version":"Preprint","quality_controlled":"1","_id":"15215","extern":"1"},{"publisher":"American Astronomical Society","abstract":[{"text":"AM CVn systems are a rare type of accreting binary that consists of a white dwarf and a helium-rich, degenerate donor star. Using the Zwicky Transient Facility (ZTF), we searched for new AM CVn systems by focusing on blue, outbursting stars. We first selected outbursting stars using the ZTF alerts. We cross matched the candidates with Gaia and Pan-STARRS catalogs. The initial selection of candidates based on the Gaia BP-RP contains 1751 unknown objects. We used the Pan-STARRS g-r and r-i color in combination with the Gaia color to identify 59 strong AM CVn candidates. We obtained identification spectra of 35 sources, of which 18 are high-priority candidates, and discovered nine new AM CVn systems and one magnetic CV that shows only He-ii lines. Using the outburst recurrence time, we estimate the orbital periods of the nine new AM CVn systems that are in the range of 29–50 minutes. We conclude that targeted follow up of blue, outbursting sources is an efficient method to find new AM CVn systems and we plan to follow up all candidates we identified to systematically study the population of outbursting AM CVn systems.","lang":"eng"}],"date_created":"2024-03-26T10:32:25Z","intvolume":"       162","language":[{"iso":"eng"}],"issue":"3","status":"public","month":"08","publication":"The Astronomical Journal","oa":1,"type":"journal_article","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"year":"2021","article_processing_charge":"No","publication_status":"published","date_published":"2021-08-19T00:00:00Z","article_number":"113","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":162,"scopus_import":"1","citation":{"short":"J. van Roestel, L. Creter, T. Kupfer, P. Szkody, J. Fuller, M.J. Green, R.M. Rich, J. Sepikas, K. Burdge, I. Caiazzo, P. Mróz, T.A. Prince, D.A. Duev, M.J. Graham, D.L. Shupe, R.R. Laher, A.A. Mahabal, F.J. Masci, The Astronomical Journal 162 (2021).","chicago":"Roestel, Jan van, Leah Creter, Thomas Kupfer, Paula Szkody, Jim Fuller, Matthew J. Green, R. Michael Rich, et al. “A Systematic Search for Outbursting AM CVn Systems with the Zwicky Transient Facility.” <i>The Astronomical Journal</i>. American Astronomical Society, 2021. <a href=\"https://doi.org/10.3847/1538-3881/ac0622\">https://doi.org/10.3847/1538-3881/ac0622</a>.","ista":"van Roestel J, Creter L, Kupfer T, Szkody P, Fuller J, Green MJ, Rich RM, Sepikas J, Burdge K, Caiazzo I, Mróz P, Prince TA, Duev DA, Graham MJ, Shupe DL, Laher RR, Mahabal AA, Masci FJ. 2021. A systematic search for outbursting AM CVn systems with the Zwicky transient facility. The Astronomical Journal. 162(3), 113.","ama":"van Roestel J, Creter L, Kupfer T, et al. A systematic search for outbursting AM CVn systems with the Zwicky transient facility. <i>The Astronomical Journal</i>. 2021;162(3). doi:<a href=\"https://doi.org/10.3847/1538-3881/ac0622\">10.3847/1538-3881/ac0622</a>","apa":"van Roestel, J., Creter, L., Kupfer, T., Szkody, P., Fuller, J., Green, M. J., … Masci, F. J. (2021). A systematic search for outbursting AM CVn systems with the Zwicky transient facility. <i>The Astronomical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-3881/ac0622\">https://doi.org/10.3847/1538-3881/ac0622</a>","ieee":"J. van Roestel <i>et al.</i>, “A systematic search for outbursting AM CVn systems with the Zwicky transient facility,” <i>The Astronomical Journal</i>, vol. 162, no. 3. American Astronomical Society, 2021.","mla":"van Roestel, Jan, et al. “A Systematic Search for Outbursting AM CVn Systems with the Zwicky Transient Facility.” <i>The Astronomical Journal</i>, vol. 162, no. 3, 113, American Astronomical Society, 2021, doi:<a href=\"https://doi.org/10.3847/1538-3881/ac0622\">10.3847/1538-3881/ac0622</a>."},"doi":"10.3847/1538-3881/ac0622","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2105.02261"}],"quality_controlled":"1","oa_version":"Preprint","extern":"1","_id":"15216","arxiv":1,"publication_identifier":{"eissn":["1538-3881"],"issn":["0004-6256"]},"article_type":"original","day":"19","external_id":{"arxiv":["2105.02261"]},"author":[{"full_name":"van Roestel, Jan","first_name":"Jan","last_name":"van Roestel"},{"first_name":"Leah","last_name":"Creter","full_name":"Creter, Leah"},{"full_name":"Kupfer, Thomas","last_name":"Kupfer","first_name":"Thomas"},{"last_name":"Szkody","first_name":"Paula","full_name":"Szkody, Paula"},{"full_name":"Fuller, Jim","first_name":"Jim","last_name":"Fuller"},{"last_name":"Green","first_name":"Matthew J.","full_name":"Green, Matthew J."},{"last_name":"Rich","first_name":"R. Michael","full_name":"Rich, R. Michael"},{"full_name":"Sepikas, John","first_name":"John","last_name":"Sepikas"},{"last_name":"Burdge","first_name":"Kevin","full_name":"Burdge, Kevin"},{"orcid":"0000-0002-4770-5388","last_name":"Caiazzo","first_name":"Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria"},{"first_name":"Przemek","last_name":"Mróz","full_name":"Mróz, Przemek"},{"full_name":"Prince, Thomas A.","last_name":"Prince","first_name":"Thomas A."},{"full_name":"Duev, Dmitry A.","first_name":"Dmitry A.","last_name":"Duev"},{"first_name":"Matthew J.","last_name":"Graham","full_name":"Graham, Matthew J."},{"first_name":"David L.","last_name":"Shupe","full_name":"Shupe, David L."},{"full_name":"Laher, Russ R.","last_name":"Laher","first_name":"Russ R."},{"full_name":"Mahabal, Ashish A.","last_name":"Mahabal","first_name":"Ashish A."},{"last_name":"Masci","first_name":"Frank J.","full_name":"Masci, Frank J."}],"date_updated":"2024-04-02T07:28:50Z","title":"A systematic search for outbursting AM CVn systems with the Zwicky transient facility"},{"author":[{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria","orcid":"0000-0002-4770-5388","last_name":"Caiazzo","first_name":"Ilaria"},{"first_name":"Kevin B.","last_name":"Burdge","full_name":"Burdge, Kevin B."},{"full_name":"Fuller, James","last_name":"Fuller","first_name":"James"},{"last_name":"Heyl","first_name":"Jeremy","full_name":"Heyl, Jeremy"},{"last_name":"Kulkarni","first_name":"S. R.","full_name":"Kulkarni, S. R."},{"first_name":"Thomas A.","last_name":"Prince","full_name":"Prince, Thomas A."},{"first_name":"Harvey B.","last_name":"Richer","full_name":"Richer, Harvey B."},{"last_name":"Schwab","first_name":"Josiah","full_name":"Schwab, Josiah"},{"full_name":"Andreoni, Igor","last_name":"Andreoni","first_name":"Igor"},{"first_name":"Eric C.","last_name":"Bellm","full_name":"Bellm, Eric C."},{"full_name":"Drake, Andrew","first_name":"Andrew","last_name":"Drake"},{"full_name":"Duev, Dmitry A.","last_name":"Duev","first_name":"Dmitry A."},{"last_name":"Graham","first_name":"Matthew J.","full_name":"Graham, Matthew J."},{"full_name":"Helou, George","first_name":"George","last_name":"Helou"},{"first_name":"Ashish A.","last_name":"Mahabal","full_name":"Mahabal, Ashish A."},{"full_name":"Masci, Frank J.","first_name":"Frank J.","last_name":"Masci"},{"first_name":"Roger","last_name":"Smith","full_name":"Smith, Roger"},{"first_name":"Maayane T.","last_name":"Soumagnac","full_name":"Soumagnac, Maayane T."}],"title":"A highly magnetized and rapidly rotating white dwarf as small as the Moon","date_updated":"2024-10-14T12:33:57Z","arxiv":1,"day":"30","related_material":{"link":[{"url":"https://doi.org/10.1038/s41586-021-03799-3","relation":"erratum"}]},"article_type":"original","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"external_id":{"arxiv":["2107.08458"]},"oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2107.08458"}],"extern":"1","_id":"15218","volume":595,"scopus_import":"1","citation":{"ieee":"I. Caiazzo <i>et al.</i>, “A highly magnetized and rapidly rotating white dwarf as small as the Moon,” <i>Nature</i>, vol. 595, no. 7865. Springer Nature, pp. 39–42, 2021.","mla":"Caiazzo, Ilaria, et al. “A Highly Magnetized and Rapidly Rotating White Dwarf as Small as the Moon.” <i>Nature</i>, vol. 595, no. 7865, Springer Nature, 2021, pp. 39–42, doi:<a href=\"https://doi.org/10.1038/s41586-021-03615-y\">10.1038/s41586-021-03615-y</a>.","apa":"Caiazzo, I., Burdge, K. B., Fuller, J., Heyl, J., Kulkarni, S. R., Prince, T. A., … Soumagnac, M. T. (2021). A highly magnetized and rapidly rotating white dwarf as small as the Moon. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-021-03615-y\">https://doi.org/10.1038/s41586-021-03615-y</a>","ista":"Caiazzo I, Burdge KB, Fuller J, Heyl J, Kulkarni SR, Prince TA, Richer HB, Schwab J, Andreoni I, Bellm EC, Drake A, Duev DA, Graham MJ, Helou G, Mahabal AA, Masci FJ, Smith R, Soumagnac MT. 2021. A highly magnetized and rapidly rotating white dwarf as small as the Moon. Nature. 595(7865), 39–42.","ama":"Caiazzo I, Burdge KB, Fuller J, et al. A highly magnetized and rapidly rotating white dwarf as small as the Moon. <i>Nature</i>. 2021;595(7865):39-42. doi:<a href=\"https://doi.org/10.1038/s41586-021-03615-y\">10.1038/s41586-021-03615-y</a>","chicago":"Caiazzo, Ilaria, Kevin B. Burdge, James Fuller, Jeremy Heyl, S. R. Kulkarni, Thomas A. Prince, Harvey B. Richer, et al. “A Highly Magnetized and Rapidly Rotating White Dwarf as Small as the Moon.” <i>Nature</i>. Springer Nature, 2021. <a href=\"https://doi.org/10.1038/s41586-021-03615-y\">https://doi.org/10.1038/s41586-021-03615-y</a>.","short":"I. Caiazzo, K.B. Burdge, J. Fuller, J. Heyl, S.R. Kulkarni, T.A. Prince, H.B. Richer, J. Schwab, I. Andreoni, E.C. Bellm, A. Drake, D.A. Duev, M.J. Graham, G. Helou, A.A. Mahabal, F.J. Masci, R. Smith, M.T. Soumagnac, Nature 595 (2021) 39–42."},"doi":"10.1038/s41586-021-03615-y","publication_status":"published","article_processing_charge":"No","year":"2021","date_published":"2021-06-30T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"39-42","oa":1,"type":"journal_article","issue":"7865","month":"06","publication":"Nature","status":"public","publisher":"Springer Nature","abstract":[{"lang":"eng","text":"White dwarfs represent the last stage of evolution of stars with mass less than about eight times that of the Sun and, like other stars, are often found in binaries1,2. If the orbital period of the binary is short enough, energy losses from gravitational-wave radiation can shrink the orbit until the two white dwarfs come into contact and merge3. Depending on the component masses, the merger can lead to a supernova of type Ia or result in a massive white dwarf4. In the latter case, the white dwarf remnant is expected to be highly magnetized5,6 because of the strong magnetic dynamo that should arise during the merger, and be rapidly spinning from the conservation of the orbital angular momentum7. Here we report observations of a white dwarf, ZTF J190132.9+145808.7, that exhibits these properties, but to an extreme: a rotation period of 6.94 minutes, a magnetic field ranging between 600 megagauss and 900 megagauss over its surface, and a stellar radius of \r\n kilometres, only slightly larger than the radius of the Moon. Such a small radius implies that the star’s mass is close to the maximum white dwarf mass, or Chandrasekhar mass. ZTF J190132.9+145808.7 is likely to be cooling through the Urca processes (neutrino emission from electron capture on sodium) because of the high densities reached in its core."}],"date_created":"2024-03-26T10:33:03Z","intvolume":"       595","language":[{"iso":"eng"}]},{"doi":"10.3847/1538-4357/abdeb7","citation":{"apa":"Richer, H. B., Caiazzo, I., Du, H., Grondin, S., Hegarty, J., Heyl, J., … Thiele, S. (2021). Massive white dwarfs in young star clusters. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/abdeb7\">https://doi.org/10.3847/1538-4357/abdeb7</a>","ista":"Richer HB, Caiazzo I, Du H, Grondin S, Hegarty J, Heyl J, Kerr R, Miller DR, Thiele S. 2021. Massive white dwarfs in young star clusters. The Astrophysical Journal. 912(2), 165.","ama":"Richer HB, Caiazzo I, Du H, et al. Massive white dwarfs in young star clusters. <i>The Astrophysical Journal</i>. 2021;912(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/abdeb7\">10.3847/1538-4357/abdeb7</a>","mla":"Richer, Harvey B., et al. “Massive White Dwarfs in Young Star Clusters.” <i>The Astrophysical Journal</i>, vol. 912, no. 2, 165, American Astronomical Society, 2021, doi:<a href=\"https://doi.org/10.3847/1538-4357/abdeb7\">10.3847/1538-4357/abdeb7</a>.","ieee":"H. B. Richer <i>et al.</i>, “Massive white dwarfs in young star clusters,” <i>The Astrophysical Journal</i>, vol. 912, no. 2. American Astronomical Society, 2021.","short":"H.B. Richer, I. Caiazzo, H. Du, S. Grondin, J. Hegarty, J. Heyl, R. Kerr, D.R. Miller, S. Thiele, The Astrophysical Journal 912 (2021).","chicago":"Richer, Harvey B., Ilaria Caiazzo, Helen Du, Steffani Grondin, James Hegarty, Jeremy Heyl, Ronan Kerr, David R. Miller, and Sarah Thiele. “Massive White Dwarfs in Young Star Clusters.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2021. <a href=\"https://doi.org/10.3847/1538-4357/abdeb7\">https://doi.org/10.3847/1538-4357/abdeb7</a>."},"scopus_import":"1","volume":912,"extern":"1","_id":"15219","quality_controlled":"1","oa_version":"Preprint","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2101.08300"}],"external_id":{"arxiv":["2101.08300"]},"day":"17","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"article_type":"original","arxiv":1,"title":"Massive white dwarfs in young star clusters","date_updated":"2024-04-03T14:11:17Z","author":[{"full_name":"Richer, Harvey B.","last_name":"Richer","first_name":"Harvey B."},{"first_name":"Ilaria","last_name":"Caiazzo","orcid":"0000-0002-4770-5388","full_name":"Caiazzo, Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d"},{"last_name":"Du","first_name":"Helen","full_name":"Du, Helen"},{"first_name":"Steffani","last_name":"Grondin","full_name":"Grondin, Steffani"},{"last_name":"Hegarty","first_name":"James","full_name":"Hegarty, James"},{"full_name":"Heyl, Jeremy","last_name":"Heyl","first_name":"Jeremy"},{"full_name":"Kerr, Ronan","last_name":"Kerr","first_name":"Ronan"},{"full_name":"Miller, David R.","first_name":"David R.","last_name":"Miller"},{"full_name":"Thiele, Sarah","last_name":"Thiele","first_name":"Sarah"}],"language":[{"iso":"eng"}],"intvolume":"       912","abstract":[{"lang":"eng","text":"We have carried out a search for massive white dwarfs (WDs) in the direction of young open star clusters using the Gaia DR2 database. The aim of this survey was (1) to provide robust data for new and previously known high-mass WDs regarding cluster membership, (2) to highlight WDs previously included in the initial final mass relation (IFMR) that are unlikely members of their respective clusters according to Gaia astrometry, and (3) to select an unequivocal WD sample that could then be compared with the host clusters' turnoff masses. All promising WD candidates in each cluster color–magnitude diagram were followed up with spectroscopy from Gemini in order to determine whether they were indeed WDs and derive their masses, temperatures, and ages. In order to be considered cluster members, white dwarfs were required to (1) have proper motions and parallaxes within 2σ, 3σ, or 4σ of those of their potential parent cluster based on how contaminated the field was in their region of the sky, (2) have a cooling age that was less than the cluster age, and (3) have a mass that was broadly consistent with the IFMR. A number of WDs included in current versions of the IFMR turned out to be nonmembers, and a number of apparent members, based on Gaia's astrometric data alone, were rejected, as their mass and/or cooling times were incompatible with cluster membership. In this way, we developed a highly selected IFMR sample for high-mass WDs that, surprisingly, contained no precursor masses significantly in excess of ∼ 6 M⊙."}],"date_created":"2024-03-26T10:33:23Z","publisher":"American Astronomical Society","status":"public","month":"05","publication":"The Astrophysical Journal","issue":"2","type":"journal_article","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-05-17T00:00:00Z","article_number":"165","publication_status":"published","year":"2021","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"article_processing_charge":"No"},{"type":"conference","conference":{"end_date":"2021-08-05","location":"San Diego, CA, United States","name":"Optical Engineering + Applications","start_date":"2021-08-01"},"day":"21","date_published":"2021-08-21T00:00:00Z","date_updated":"2024-04-03T14:13:09Z","title":"The Globe Orbiting Soft X-ray (GOSoX) polarimeter concept study","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Marshall","first_name":"Herman L.","full_name":"Marshall, Herman L."},{"full_name":"Heine, Sarah","last_name":"Heine","first_name":"Sarah"},{"full_name":"Davidson, Rosemary","first_name":"Rosemary","last_name":"Davidson"},{"last_name":"Garner","first_name":"Alan","full_name":"Garner, Alan"},{"first_name":"Eric","last_name":"Gullikson","full_name":"Gullikson, Eric"},{"last_name":"Günther","first_name":"Moritz","full_name":"Günther, Moritz"},{"full_name":"Leitz, Christopher","last_name":"Leitz","first_name":"Christopher"},{"full_name":"Masterson, Rebecca","first_name":"Rebecca","last_name":"Masterson"},{"full_name":"Miller, Eric","last_name":"Miller","first_name":"Eric"},{"full_name":"Stenzel, June S.","first_name":"June S.","last_name":"Stenzel"},{"full_name":"Zhang, William W.","first_name":"William W.","last_name":"Zhang"},{"first_name":"Rozenn","last_name":"Boissay-Malaquin","full_name":"Boissay-Malaquin, Rozenn"},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","full_name":"Caiazzo, Ilaria","orcid":"0000-0002-4770-5388","last_name":"Caiazzo","first_name":"Ilaria"},{"first_name":"Deepto","last_name":"Chakrabarty","full_name":"Chakrabarty, Deepto"},{"first_name":"Luigi","last_name":"Gallo","full_name":"Gallo, Luigi"},{"last_name":"Heilmann","first_name":"Ralf","full_name":"Heilmann, Ralf"},{"full_name":"Heyl, Jeremy","first_name":"Jeremy","last_name":"Heyl"},{"full_name":"Kara, Erin","first_name":"Erin","last_name":"Kara"},{"full_name":"Schulz, Norbert","first_name":"Norbert","last_name":"Schulz"}],"article_processing_charge":"No","year":"2021","publication_status":"published","citation":{"apa":"Marshall, H. L., Heine, S., Davidson, R., Garner, A., Gullikson, E., Günther, M., … Schulz, N. (2021). The Globe Orbiting Soft X-ray (GOSoX) polarimeter concept study. In <i>Optics for EUV, X-Ray, and Gamma-Ray Astronomy X</i> (Vol. 11822). San Diego, CA, United States: SPIE. <a href=\"https://doi.org/10.1117/12.2596186\">https://doi.org/10.1117/12.2596186</a>","ama":"Marshall HL, Heine S, Davidson R, et al. The Globe Orbiting Soft X-ray (GOSoX) polarimeter concept study. In: <i>Optics for EUV, X-Ray, and Gamma-Ray Astronomy X</i>. Vol 11822. SPIE; 2021. doi:<a href=\"https://doi.org/10.1117/12.2596186\">10.1117/12.2596186</a>","ista":"Marshall HL, Heine S, Davidson R, Garner A, Gullikson E, Günther M, Leitz C, Masterson R, Miller E, Stenzel JS, Zhang WW, Boissay-Malaquin R, Caiazzo I, Chakrabarty D, Gallo L, Heilmann R, Heyl J, Kara E, Schulz N. 2021. The Globe Orbiting Soft X-ray (GOSoX) polarimeter concept study. Optics for EUV, X-Ray, and Gamma-Ray Astronomy X. Optical Engineering + Applications vol. 11822.","mla":"Marshall, Herman L., et al. “The Globe Orbiting Soft X-Ray (GOSoX) Polarimeter Concept Study.” <i>Optics for EUV, X-Ray, and Gamma-Ray Astronomy X</i>, vol. 11822, SPIE, 2021, doi:<a href=\"https://doi.org/10.1117/12.2596186\">10.1117/12.2596186</a>.","ieee":"H. L. Marshall <i>et al.</i>, “The Globe Orbiting Soft X-ray (GOSoX) polarimeter concept study,” in <i>Optics for EUV, X-Ray, and Gamma-Ray Astronomy X</i>, San Diego, CA, United States, 2021, vol. 11822.","short":"H.L. Marshall, S. Heine, R. Davidson, A. Garner, E. Gullikson, M. Günther, C. Leitz, R. Masterson, E. Miller, J.S. Stenzel, W.W. Zhang, R. Boissay-Malaquin, I. Caiazzo, D. Chakrabarty, L. Gallo, R. Heilmann, J. Heyl, E. Kara, N. Schulz, in:, Optics for EUV, X-Ray, and Gamma-Ray Astronomy X, SPIE, 2021.","chicago":"Marshall, Herman L., Sarah Heine, Rosemary Davidson, Alan Garner, Eric Gullikson, Moritz Günther, Christopher Leitz, et al. “The Globe Orbiting Soft X-Ray (GOSoX) Polarimeter Concept Study.” In <i>Optics for EUV, X-Ray, and Gamma-Ray Astronomy X</i>, Vol. 11822. SPIE, 2021. <a href=\"https://doi.org/10.1117/12.2596186\">https://doi.org/10.1117/12.2596186</a>."},"doi":"10.1117/12.2596186","intvolume":"     11822","language":[{"iso":"eng"}],"volume":11822,"publisher":"SPIE","abstract":[{"lang":"eng","text":"We describe an implementation of a broad-band soft X-ray polarimeter, substantially based on previous designs. The Globe-Orbiting Soft X-ray Polarimeter (GOSoX) is a SmallSat. As in a related mission concept the PiSoX Polarimeter, the grating arrangement is designed optimally for the purpose of polarimetry matching the dispersion of a spectrometer to a laterally graded multilayer (LGML). For GOSoX, the optics are lightweight Si mirrors in a one-bounce parabolic configuration. The instrument covers the wavelength range from 31 A to 75 A (165 - 400 eV). Upon satellite rotation, the intensities of the dispersed spectra, after reflection and polarizing by the LGMLs, give the three Stokes parameters needed to determine a source's linear polarization fraction and orientation. The design can be extended to higher energies as LGMLs are developed further. We describe the potential scientific return and the proposed mission concept following the results of a JPL Team X concept study."}],"date_created":"2024-03-26T10:34:21Z","scopus_import":"1","quality_controlled":"1","month":"08","oa_version":"None","publication":"Optics for EUV, X-Ray, and Gamma-Ray Astronomy X","status":"public","_id":"15222","extern":"1"},{"author":[{"last_name":"Li","first_name":"Sijie","full_name":"Li, Sijie"},{"first_name":"Rawad","last_name":"Bitar","full_name":"Bitar, Rawad"},{"full_name":"Jaggi, Sidharth","last_name":"Jaggi","first_name":"Sidharth"},{"first_name":"Yihan","orcid":"0000-0002-6465-6258","last_name":"Zhang","id":"2ce5da42-b2ea-11eb-bba5-9f264e9d002c","full_name":"Zhang, Yihan"}],"title":"Network coding with myopic adversaries","date_updated":"2024-04-02T08:31:59Z","arxiv":1,"day":"01","acknowledgement":"The work of Rawad Bitar was supported in part by the Technical University of Munich—Institute for Advanced Studies, funded by the German Excellence Initiative and European Union Seventh Framework Programme under Grant 291763. The work of Sidharth Jaggi was supported by the Hong Kong UGC GRF under Grant 14304418, Grant 14300617, and Grant 14313116. The work of Yihan Zhang was supported by the European Union’s Horizon 2020 Research and Innovation Programme under Grant 682203-ERC-[Inf-Speed-Tradeoff]. Preliminary results were presented at IEEE International Symposium on information Theory (ISIT).","article_type":"original","publication_identifier":{"eissn":["2641-8770"]},"external_id":{"arxiv":["2102.09885"]},"oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2102.09885"}],"_id":"15254","volume":2,"department":[{"_id":"MaMo"}],"scopus_import":"1","doi":"10.1109/JSAIT.2021.3126474","citation":{"short":"S. Li, R. Bitar, S. Jaggi, Y. Zhang, IEEE Journal on Selected Areas in Information Theory 2 (2021) 1108–1119.","chicago":"Li, Sijie, Rawad Bitar, Sidharth Jaggi, and Yihan Zhang. “Network Coding with Myopic Adversaries.” <i>IEEE Journal on Selected Areas in Information Theory</i>. IEEE, 2021. <a href=\"https://doi.org/10.1109/JSAIT.2021.3126474\">https://doi.org/10.1109/JSAIT.2021.3126474</a>.","apa":"Li, S., Bitar, R., Jaggi, S., &#38; Zhang, Y. (2021). Network coding with myopic adversaries. <i>IEEE Journal on Selected Areas in Information Theory</i>. IEEE. <a href=\"https://doi.org/10.1109/JSAIT.2021.3126474\">https://doi.org/10.1109/JSAIT.2021.3126474</a>","ista":"Li S, Bitar R, Jaggi S, Zhang Y. 2021. Network coding with myopic adversaries. IEEE Journal on Selected Areas in Information Theory. 2(4), 1108–1119.","ama":"Li S, Bitar R, Jaggi S, Zhang Y. Network coding with myopic adversaries. <i>IEEE Journal on Selected Areas in Information Theory</i>. 2021;2(4):1108-1119. doi:<a href=\"https://doi.org/10.1109/JSAIT.2021.3126474\">10.1109/JSAIT.2021.3126474</a>","ieee":"S. Li, R. Bitar, S. Jaggi, and Y. Zhang, “Network coding with myopic adversaries,” <i>IEEE Journal on Selected Areas in Information Theory</i>, vol. 2, no. 4. IEEE, pp. 1108–1119, 2021.","mla":"Li, Sijie, et al. “Network Coding with Myopic Adversaries.” <i>IEEE Journal on Selected Areas in Information Theory</i>, vol. 2, no. 4, IEEE, 2021, pp. 1108–19, doi:<a href=\"https://doi.org/10.1109/JSAIT.2021.3126474\">10.1109/JSAIT.2021.3126474</a>."},"publication_status":"published","article_processing_charge":"No","year":"2021","date_published":"2021-12-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"1108-1119","oa":1,"type":"journal_article","issue":"4","publication":"IEEE Journal on Selected Areas in Information Theory","status":"public","month":"12","publisher":"IEEE","abstract":[{"text":"We consider the problem of reliable communication over a network containing a hidden myopic adversary who can eavesdrop on some zro links, jam some zwo links, and do both on some zrw links. We provide the first information-theoretically tight characterization of the optimal rate of communication possible under all possible settings of the tuple (zro,zwo,zrw) by providing a novel coding scheme/analysis for a subset of parameter regimes. In particular, our vanishing-error schemes bypass the Network Singleton Bound (which requires a zero-error recovery criteria) in a certain parameter regime where the capacity had been heretofore open. As a direct corollary we also obtain the capacity of the corresponding problem where information-theoretic secrecy against eavesdropping is required in addition to reliable communication.","lang":"eng"}],"date_created":"2024-03-31T22:01:13Z","intvolume":"         2","language":[{"iso":"eng"}]},{"publication_status":"published","keyword":["Statistics","Probability and Uncertainty","Statistics and Probability"],"article_processing_charge":"No","year":"2021","date_published":"2021-07-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","page":"1886-1916","oa":1,"type":"journal_article","isi":1,"ec_funded":1,"issue":"4","publication":"The Annals of Probability","status":"public","corr_author":"1","month":"07","publisher":"Institute of Mathematical Statistics","date_created":"2024-04-03T07:19:42Z","abstract":[{"text":"We consider words Gi1⋯Gim involving i.i.d. complex Ginibre matrices and study tracial expressions of their eigenvalues and singular values. We show that the limit distribution of the squared singular values of every word of length m is a Fuss–Catalan distribution with parameter \r\nm+1. This generalizes previous results concerning powers of a complex Ginibre matrix and products of independent Ginibre matrices. In addition, we find other combinatorial parameters of the word that determine the second-order limits of the spectral statistics. For instance, the so-called coperiod of a word characterizes the fluctuations of the eigenvalues. We extend these results to words of general non-Hermitian matrices with i.i.d. entries under moment-matching assumptions, band matrices, and sparse matrices.\r\nThese results rely on the moments method and genus expansion, relating Gaussian matrix integrals to the counting of compact orientable surfaces of a given genus. This allows us to derive a central limit theorem for the trace of any word of complex Ginibre matrices and their conjugate transposes, where all parameters are defined topologically.","lang":"eng"}],"intvolume":"        49","language":[{"iso":"eng"}],"author":[{"first_name":"Guillaume","orcid":"0000-0001-6892-8137","last_name":"Dubach","id":"D5C6A458-10C4-11EA-ABF4-A4B43DDC885E","full_name":"Dubach, Guillaume"},{"full_name":"Peled, Yuval","first_name":"Yuval","last_name":"Peled"}],"title":"On words of non-Hermitian random matrices","date_updated":"2025-09-10T10:13:20Z","arxiv":1,"day":"01","article_type":"original","acknowledgement":"The authors would like to thank Gernot Akemann, Benson Au, Paul Bourgade, Jesper Ipsen, Camille Male, Jamie Mingo, Doron Puder, Emily Redelmeier, Roland Speicher, Wojciech Tarnowski and Ofer Zeitouni for useful discussions, comments and references as well as the anonymous referee for a suggestion that greatly improved one of the theorems.\r\nG.D. gratefully acknowledges support from the grants NSF DMS-1812114 of P. Bourgade (PI) and NSF CAREER DMS-1653602 of L.-P. Arguin (PI), as well as the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411.","publication_identifier":{"issn":["0091-1798"]},"external_id":{"arxiv":["1904.04312"],"isi":["000681349000008"]},"oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1904.04312","open_access":"1"}],"_id":"15259","volume":49,"scopus_import":"1","department":[{"_id":"LaEr"}],"doi":"10.1214/20-aop1496","citation":{"mla":"Dubach, Guillaume, and Yuval Peled. “On Words of Non-Hermitian Random Matrices.” <i>The Annals of Probability</i>, vol. 49, no. 4, Institute of Mathematical Statistics, 2021, pp. 1886–916, doi:<a href=\"https://doi.org/10.1214/20-aop1496\">10.1214/20-aop1496</a>.","ieee":"G. Dubach and Y. Peled, “On words of non-Hermitian random matrices,” <i>The Annals of Probability</i>, vol. 49, no. 4. Institute of Mathematical Statistics, pp. 1886–1916, 2021.","ista":"Dubach G, Peled Y. 2021. On words of non-Hermitian random matrices. The Annals of Probability. 49(4), 1886–1916.","apa":"Dubach, G., &#38; Peled, Y. (2021). On words of non-Hermitian random matrices. <i>The Annals of Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/20-aop1496\">https://doi.org/10.1214/20-aop1496</a>","ama":"Dubach G, Peled Y. On words of non-Hermitian random matrices. <i>The Annals of Probability</i>. 2021;49(4):1886-1916. doi:<a href=\"https://doi.org/10.1214/20-aop1496\">10.1214/20-aop1496</a>","chicago":"Dubach, Guillaume, and Yuval Peled. “On Words of Non-Hermitian Random Matrices.” <i>The Annals of Probability</i>. Institute of Mathematical Statistics, 2021. <a href=\"https://doi.org/10.1214/20-aop1496\">https://doi.org/10.1214/20-aop1496</a>.","short":"G. Dubach, Y. Peled, The Annals of Probability 49 (2021) 1886–1916."},"project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}]},{"publication":"Chemistry of Materials","status":"public","month":"12","issue":"24","intvolume":"        33","language":[{"iso":"eng"}],"publisher":"American Chemical Society","date_created":"2024-04-03T07:23:30Z","abstract":[{"text":"Significant advances in the synthesis and processing of colloidal nanocrystals have given scientists and engineers access to a vast library of building blocks with precisely defined size, shape, and composition. These materials have inspired exciting prospects to enable bottom-up fabrication of programmable materials with properties by design. Successfully assembling and connecting the building blocks into superstructures in which constituent nanocrystals can purposefully interact requires robust understanding of and control over a complex interplay of dynamic physicochemical processes. Fluid interfaces provide an advantageous experimental workbench to both probe and control these processes. Despite the ostensible simplicity of fabricating nanocrystal assemblies at a fluid interface, sensitivity to processing conditions and limited reproducibility have underscored the complexity of this process. In situ studies have provided mechanistic insights into the competing dynamics of key subprocesses including solvent spreading and evaporation, superlattice formation, ligand detachment kinetics, and nanocrystal attachment. Understanding how these subprocesses influence the complex choreography of self-assembly, structure transformation, and oriented attachment processes presents a rich research challenge. In this context, we present a detailed methodology for self-assembly and attachment of lead chalcogenide nanocrystals at a liquid–gas interface as a model system for the fabrication of mono- and multilayer cubic connected superlattices. We discuss key experimental parameters such as the characteristics of the building blocks and processing conditions and detailed steps from colloidal nanocrystal injection to superlattice transfer. We hope that this Methods/Protocols paper will provide guidance for future advances in the exciting path toward bringing the prospect of nanocrystal-based programmable materials to fruition.","lang":"eng"}],"date_published":"2021-12-16T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Materials Chemistry","General Chemical Engineering","General Chemistry"],"year":"2021","article_processing_charge":"No","publication_status":"published","oa":1,"type":"journal_article","page":"9457-9472","main_file_link":[{"open_access":"1","url":"https://www.osti.gov/servlets/purl/1836502"}],"quality_controlled":"1","oa_version":"Submitted Version","_id":"15260","citation":{"short":"J. Cimada daSilva, D. Balazs, T.A. Dunbar, T. Hanrath, Chemistry of Materials 33 (2021) 9457–9472.","chicago":"Cimada daSilva, Jessica, Daniel Balazs, Tyler A. Dunbar, and Tobias Hanrath. “Fundamental Processes and Practical Considerations of Lead Chalcogenide Mesocrystals Formed via Self-Assembly and Directed Attachment of Nanocrystals at a Fluid Interface.” <i>Chemistry of Materials</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">https://doi.org/10.1021/acs.chemmater.1c02910</a>.","apa":"Cimada daSilva, J., Balazs, D., Dunbar, T. A., &#38; Hanrath, T. (2021). Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. <i>Chemistry of Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">https://doi.org/10.1021/acs.chemmater.1c02910</a>","ista":"Cimada daSilva J, Balazs D, Dunbar TA, Hanrath T. 2021. Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. Chemistry of Materials. 33(24), 9457–9472.","ama":"Cimada daSilva J, Balazs D, Dunbar TA, Hanrath T. Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface. <i>Chemistry of Materials</i>. 2021;33(24):9457-9472. doi:<a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">10.1021/acs.chemmater.1c02910</a>","ieee":"J. Cimada daSilva, D. Balazs, T. A. Dunbar, and T. Hanrath, “Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface,” <i>Chemistry of Materials</i>, vol. 33, no. 24. American Chemical Society, pp. 9457–9472, 2021.","mla":"Cimada daSilva, Jessica, et al. “Fundamental Processes and Practical Considerations of Lead Chalcogenide Mesocrystals Formed via Self-Assembly and Directed Attachment of Nanocrystals at a Fluid Interface.” <i>Chemistry of Materials</i>, vol. 33, no. 24, American Chemical Society, 2021, pp. 9457–72, doi:<a href=\"https://doi.org/10.1021/acs.chemmater.1c02910\">10.1021/acs.chemmater.1c02910</a>."},"doi":"10.1021/acs.chemmater.1c02910","volume":33,"scopus_import":"1","department":[{"_id":"LifeSc"}],"date_updated":"2024-04-03T13:50:53Z","title":"Fundamental processes and practical considerations of lead chalcogenide mesocrystals formed via self-assembly and directed attachment of nanocrystals at a fluid interface","author":[{"full_name":"Cimada daSilva, Jessica","last_name":"Cimada daSilva","first_name":"Jessica"},{"orcid":"0000-0001-7597-043X","last_name":"Balazs","first_name":"Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","full_name":"Balazs, Daniel"},{"first_name":"Tyler A.","last_name":"Dunbar","full_name":"Dunbar, Tyler A."},{"last_name":"Hanrath","first_name":"Tobias","full_name":"Hanrath, Tobias"}],"publication_identifier":{"issn":["0897-4756"],"eissn":["1520-5002"]},"article_type":"original","day":"16"},{"citation":{"chicago":"Lenz, Daniel, Marcel Schmidt, and Melchior Wirth. “Uniqueness of Form Extensions and Domination of Semigroups.” <i>Journal of Functional Analysis</i>. Elsevier, 2021. <a href=\"https://doi.org/10.1016/j.jfa.2020.108848\">https://doi.org/10.1016/j.jfa.2020.108848</a>.","short":"D. Lenz, M. Schmidt, M. Wirth, Journal of Functional Analysis 280 (2021).","ieee":"D. Lenz, M. Schmidt, and M. Wirth, “Uniqueness of form extensions and domination of semigroups,” <i>Journal of Functional Analysis</i>, vol. 280, no. 6. Elsevier, 2021.","mla":"Lenz, Daniel, et al. “Uniqueness of Form Extensions and Domination of Semigroups.” <i>Journal of Functional Analysis</i>, vol. 280, no. 6, 108848, Elsevier, 2021, doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108848\">10.1016/j.jfa.2020.108848</a>.","ama":"Lenz D, Schmidt M, Wirth M. Uniqueness of form extensions and domination of semigroups. <i>Journal of Functional Analysis</i>. 2021;280(6). doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108848\">10.1016/j.jfa.2020.108848</a>","apa":"Lenz, D., Schmidt, M., &#38; Wirth, M. (2021). Uniqueness of form extensions and domination of semigroups. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2020.108848\">https://doi.org/10.1016/j.jfa.2020.108848</a>","ista":"Lenz D, Schmidt M, Wirth M. 2021. Uniqueness of form extensions and domination of semigroups. Journal of Functional Analysis. 280(6), 108848."},"doi":"10.1016/j.jfa.2020.108848","volume":280,"scopus_import":"1","department":[{"_id":"JaMa"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.jfa.2020.108848"}],"quality_controlled":"1","oa_version":"Published Version","_id":"15261","OA_place":"publisher","article_type":"original","publication_identifier":{"eissn":["1096-0783"],"issn":["0022-1236"]},"day":"15","date_updated":"2026-06-18T17:46:54Z","title":"Uniqueness of form extensions and domination of semigroups","author":[{"last_name":"Lenz","first_name":"Daniel","full_name":"Lenz, Daniel"},{"full_name":"Schmidt, Marcel","last_name":"Schmidt","first_name":"Marcel"},{"id":"88644358-0A0E-11EA-8FA5-49A33DDC885E","full_name":"Wirth, Melchior","orcid":"0000-0002-0519-4241","last_name":"Wirth","first_name":"Melchior"}],"intvolume":"       280","language":[{"iso":"eng"}],"OA_type":"free access","publisher":"Elsevier","abstract":[{"text":"In this article, we study uniqueness of form extensions in a rather general setting. The method is based on the theory of ordered Hilbert spaces and the concept of domination of semigroups. Our main abstract result transfers uniqueness of form extension of a dominating form to that of a dominated form. This result can be applied to a multitude of examples including various magnetic Schrödinger forms on graphs and on manifolds.","lang":"eng"}],"date_created":"2024-04-03T07:24:57Z","status":"public","publication":"Journal of Functional Analysis","corr_author":"1","month":"03","ddc":["500"],"issue":"6","oa":1,"type":"journal_article","date_published":"2021-03-15T00:00:00Z","article_number":"108848","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Analysis"],"year":"2021","article_processing_charge":"No","publication_status":"published"},{"publication_status":"published","article_processing_charge":"No","year":"2021","date_published":"2021-04-15T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"1351-1359","oa":1,"type":"conference","publication":"Proceedings of the 24th International Conference on Artificial Intelligence and Statistics","status":"public","month":"04","ddc":["000"],"publisher":"ML Research Press","date_created":"2024-04-03T07:29:49Z","abstract":[{"lang":"eng","text":"We develop a new Riemannian descent algorithm that relies on momentum to improve over existing first-order methods for geodesically convex optimization. In contrast, accelerated convergence rates proved in prior work have only been shown to hold for geodesically strongly-convex objective functions. We further extend our algorithm to geodesically weakly-quasi-convex objectives. Our proofs of convergence rely on a novel estimate sequence that illustrates the dependency of the convergence rate on the curvature of the manifold. We validate our theoretical results empirically on several optimization problems defined on the sphere and on the manifold of positive definite matrices."}],"alternative_title":["PMLR"],"intvolume":"       130","language":[{"iso":"eng"}],"author":[{"first_name":"Foivos","last_name":"Alimisis","id":"19430a34-05f6-11ef-890d-c079cfc60ae2","full_name":"Alimisis, Foivos"},{"first_name":"Antonio","last_name":"Orvieto","full_name":"Orvieto, Antonio"},{"full_name":"Becigneul, Gary","last_name":"Becigneul","first_name":"Gary"},{"first_name":"Aurelien","last_name":"Lucchi","full_name":"Lucchi, Aurelien"}],"title":"Momentum improves optimization on Riemannian manifolds","date_updated":"2026-06-18T17:47:19Z","arxiv":1,"day":"15","acknowledgement":"The authors would like to thank professors Nicolas Boumal and Suvrit Sra for helpful discussions on the content of this paper. Gary Bécigneul was funded by the Max Planck ETH Center for Learning Systems during the course of this work.","external_id":{"arxiv":["2002.04144"]},"conference":{"start_date":"2021-04-13","name":"AISTATS: Conference on Artificial Intelligence and Statistics","location":"San Diego, CA, United States; Virtual","end_date":"2021-04-15"},"quality_controlled":"1","oa_version":"Published Version","main_file_link":[{"url":"https://proceedings.mlr.press/v130/alimisis21a.html","open_access":"1"}],"_id":"15263","volume":130,"department":[{"_id":"DaAl"}],"citation":{"short":"F. Alimisis, A. Orvieto, G. Becigneul, A. Lucchi, in:, Proceedings of the 24th International Conference on Artificial Intelligence and Statistics, ML Research Press, 2021, pp. 1351–1359.","chicago":"Alimisis, Foivos, Antonio Orvieto, Gary Becigneul, and Aurelien Lucchi. “Momentum Improves Optimization on Riemannian Manifolds.” In <i>Proceedings of the 24th International Conference on Artificial Intelligence and Statistics</i>, 130:1351–59. ML Research Press, 2021.","ista":"Alimisis F, Orvieto A, Becigneul G, Lucchi A. 2021. Momentum improves optimization on Riemannian manifolds. Proceedings of the 24th International Conference on Artificial Intelligence and Statistics. AISTATS: Conference on Artificial Intelligence and Statistics, PMLR, vol. 130, 1351–1359.","apa":"Alimisis, F., Orvieto, A., Becigneul, G., &#38; Lucchi, A. (2021). Momentum improves optimization on Riemannian manifolds. In <i>Proceedings of the 24th International Conference on Artificial Intelligence and Statistics</i> (Vol. 130, pp. 1351–1359). San Diego, CA, United States; Virtual: ML Research Press.","ama":"Alimisis F, Orvieto A, Becigneul G, Lucchi A. Momentum improves optimization on Riemannian manifolds. In: <i>Proceedings of the 24th International Conference on Artificial Intelligence and Statistics</i>. Vol 130. ML Research Press; 2021:1351-1359.","mla":"Alimisis, Foivos, et al. “Momentum Improves Optimization on Riemannian Manifolds.” <i>Proceedings of the 24th International Conference on Artificial Intelligence and Statistics</i>, vol. 130, ML Research Press, 2021, pp. 1351–59.","ieee":"F. Alimisis, A. Orvieto, G. Becigneul, and A. Lucchi, “Momentum improves optimization on Riemannian manifolds,” in <i>Proceedings of the 24th International Conference on Artificial Intelligence and Statistics</i>, San Diego, CA, United States; Virtual, 2021, vol. 130, pp. 1351–1359."}},{"intvolume":"         9","language":[{"iso":"eng"}],"publisher":"Frontiers Media","has_accepted_license":"1","abstract":[{"lang":"eng","text":"Signaling by the B cell antigen receptor (BCR) initiates actin remodeling. The assembly of branched actin networks that are nucleated by the Arp2/3 complex exert outward force on the plasma membrane, allowing B cells to form membrane protrusions that can scan the surface of antigen-presenting cells (APCs). The resulting Arp2/3 complex-dependent actin retrograde flow promotes the centripetal movement and progressive coalescence of BCR microclusters, which amplifies BCR signaling. Glia maturation factor γ (GMFγ) is an actin disassembly-protein that releases Arp2/3 complex-nucleated actin filaments from actin networks. By doing so, GMFγ could either oppose the actions of the Arp2/3 complex or support Arp2/3 complex-nucleated actin polymerization by contributing to the recycling of actin monomers and Arp2/3 complexes. We now show that reducing the levels of GMFγ in human B cell lines via transfection with a specific siRNA impairs the ability of B cells to spread on antigen-coated surfaces, decreases the velocity of actin retrograde flow, diminishes the coalescence of BCR microclusters into a central cluster at the B cell-APC contact site, and decreases APC-induced BCR signaling. These effects of depleting GMFγ are similar to what occurs when the Arp2/3 complex is inhibited. This suggests that GMFγ cooperates with the Arp2/3 complex to support BCR-induced actin remodeling and amplify BCR signaling at the immune synapse."}],"date_created":"2024-04-03T07:34:08Z","pmid":1,"publication":"Frontiers in Cell and Developmental Biology","status":"public","month":"07","ddc":["570"],"oa":1,"type":"journal_article","article_number":"647063","date_published":"2021-07-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"success":1,"file_id":"15291","date_updated":"2024-04-03T14:08:05Z","creator":"dernst","file_name":"2021_Frontiers_Deretic.pdf","checksum":"f6330b5c6718d6780383c0300fd4ef12","date_created":"2024-04-03T14:08:05Z","relation":"main_file","access_level":"open_access","content_type":"application/pdf","file_size":7430029}],"publication_status":"published","year":"2021","keyword":["Cell Biology","Developmental Biology"],"article_processing_charge":"No","citation":{"chicago":"Deretic, Nikola, Madison Bolger-Munro, Kate Choi, Libin Abraham, and Michael R. Gold. “The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse.” <i>Frontiers in Cell and Developmental Biology</i>. Frontiers Media, 2021. <a href=\"https://doi.org/10.3389/fcell.2021.647063\">https://doi.org/10.3389/fcell.2021.647063</a>.","short":"N. Deretic, M. Bolger-Munro, K. Choi, L. Abraham, M.R. Gold, Frontiers in Cell and Developmental Biology 9 (2021).","mla":"Deretic, Nikola, et al. “The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse.” <i>Frontiers in Cell and Developmental Biology</i>, vol. 9, 647063, Frontiers Media, 2021, doi:<a href=\"https://doi.org/10.3389/fcell.2021.647063\">10.3389/fcell.2021.647063</a>.","ieee":"N. Deretic, M. Bolger-Munro, K. Choi, L. Abraham, and M. R. Gold, “The actin-disassembly protein glia maturation factor γ enhances actin remodeling and B cell antigen receptor signaling at the immune synapse,” <i>Frontiers in Cell and Developmental Biology</i>, vol. 9. Frontiers Media, 2021.","ista":"Deretic N, Bolger-Munro M, Choi K, Abraham L, Gold MR. 2021. The actin-disassembly protein glia maturation factor γ enhances actin remodeling and B cell antigen receptor signaling at the immune synapse. Frontiers in Cell and Developmental Biology. 9, 647063.","ama":"Deretic N, Bolger-Munro M, Choi K, Abraham L, Gold MR. The actin-disassembly protein glia maturation factor γ enhances actin remodeling and B cell antigen receptor signaling at the immune synapse. <i>Frontiers in Cell and Developmental Biology</i>. 2021;9. doi:<a href=\"https://doi.org/10.3389/fcell.2021.647063\">10.3389/fcell.2021.647063</a>","apa":"Deretic, N., Bolger-Munro, M., Choi, K., Abraham, L., &#38; Gold, M. R. (2021). The actin-disassembly protein glia maturation factor γ enhances actin remodeling and B cell antigen receptor signaling at the immune synapse. <i>Frontiers in Cell and Developmental Biology</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fcell.2021.647063\">https://doi.org/10.3389/fcell.2021.647063</a>"},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.3389/fcell.2021.647063","volume":9,"scopus_import":"1","department":[{"_id":"CaHe"}],"oa_version":"Published Version","quality_controlled":"1","_id":"15264","external_id":{"pmid":["34336818"]},"day":"01","file_date_updated":"2024-04-03T14:08:05Z","article_type":"original","publication_identifier":{"issn":["2296-634X"]},"title":"The actin-disassembly protein glia maturation factor γ enhances actin remodeling and B cell antigen receptor signaling at the immune synapse","date_updated":"2024-04-03T14:10:25Z","author":[{"first_name":"Nikola","last_name":"Deretic","full_name":"Deretic, Nikola"},{"orcid":"0000-0002-8176-4824","last_name":"Bolger-Munro","first_name":"Madison","id":"516F03FA-93A3-11EA-A7C5-D6BE3DDC885E","full_name":"Bolger-Munro, Madison"},{"last_name":"Choi","first_name":"Kate","full_name":"Choi, Kate"},{"full_name":"Abraham, Libin","first_name":"Libin","last_name":"Abraham"},{"full_name":"Gold, Michael R.","first_name":"Michael R.","last_name":"Gold"}]},{"page":"2825-2837","type":"journal_article","article_processing_charge":"No","keyword":["Materials Chemistry","Energy Engineering and Power Technology","Fuel Technology","Renewable Energy","Sustainability and the Environment","Chemistry (miscellaneous)"],"year":"2021","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2021-07-21T00:00:00Z","abstract":[{"text":"The highly enhanced thermoelectric figure of merit, zT ≈ 2.6 at 573 K, obtained recently in Cd-doped polycrystalline AgSbTe2 by Roychowdhury et al. ( Science 2021, 371, 722) brings it to the forefront of thermoelectric and energy materials research. Ag/Sb cationic ordering in polycrystalline AgSbTe2 was a challenging issue for a long time: their ordered arrangement in the cationic sublattice in polycrystalline samples remained elusive despite multiple theoretical predictions and experimental studies. Recently, selective cation doping has been used to enhance the Ag/Sb ordering, and cation ordered nanoscale (2–4 nm) domains were observed in polycrystalline AgSbTe2, which reduce lattice thermal conductivity. The enhanced cation ordering also delocalizes disorder-induced localized electronic states, and consequently the electronic transport enhances. In this Focus Review, we provide the details of the rational design of a high-performance thermoelectric material using the recently developed atomic order–disorder optimization strategy with AgSbTe2 as an example. Atomic disorder is ubiquitous in most thermoelectric materials, and the atomic order–disorder optimization strategy applies to a large variety of thermoelectric materials.","lang":"eng"}],"date_created":"2024-04-03T07:36:10Z","publisher":"American Chemical Society","language":[{"iso":"eng"}],"intvolume":"         6","issue":"8","status":"public","publication":"ACS Energy Letters","month":"07","publication_identifier":{"issn":["2380-8195"]},"article_type":"original","day":"21","author":[{"last_name":"Ghosh","first_name":"Tanmoy","full_name":"Ghosh, Tanmoy","id":"a5fc9bc3-feff-11ea-93fe-e8015a3c7e9d"},{"last_name":"Roychowdhury","first_name":"Subhajit","full_name":"Roychowdhury, Subhajit"},{"full_name":"Dutta, Moinak","last_name":"Dutta","first_name":"Moinak"},{"first_name":"Kanishka","last_name":"Biswas","full_name":"Biswas, Kanishka"}],"date_updated":"2024-04-29T06:56:57Z","title":"High-performance thermoelectric energy conversion: A tale of atomic ordering in AgSbTe2","department":[{"_id":"MaIb"}],"volume":6,"citation":{"chicago":"Ghosh, Tanmoy, Subhajit Roychowdhury, Moinak Dutta, and Kanishka Biswas. “High-Performance Thermoelectric Energy Conversion: A Tale of Atomic Ordering in AgSbTe2.” <i>ACS Energy Letters</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acsenergylett.1c01184\">https://doi.org/10.1021/acsenergylett.1c01184</a>.","short":"T. Ghosh, S. Roychowdhury, M. Dutta, K. Biswas, ACS Energy Letters 6 (2021) 2825–2837.","mla":"Ghosh, Tanmoy, et al. “High-Performance Thermoelectric Energy Conversion: A Tale of Atomic Ordering in AgSbTe2.” <i>ACS Energy Letters</i>, vol. 6, no. 8, American Chemical Society, 2021, pp. 2825–37, doi:<a href=\"https://doi.org/10.1021/acsenergylett.1c01184\">10.1021/acsenergylett.1c01184</a>.","ieee":"T. Ghosh, S. Roychowdhury, M. Dutta, and K. Biswas, “High-performance thermoelectric energy conversion: A tale of atomic ordering in AgSbTe2,” <i>ACS Energy Letters</i>, vol. 6, no. 8. American Chemical Society, pp. 2825–2837, 2021.","apa":"Ghosh, T., Roychowdhury, S., Dutta, M., &#38; Biswas, K. (2021). High-performance thermoelectric energy conversion: A tale of atomic ordering in AgSbTe2. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.1c01184\">https://doi.org/10.1021/acsenergylett.1c01184</a>","ista":"Ghosh T, Roychowdhury S, Dutta M, Biswas K. 2021. High-performance thermoelectric energy conversion: A tale of atomic ordering in AgSbTe2. ACS Energy Letters. 6(8), 2825–2837.","ama":"Ghosh T, Roychowdhury S, Dutta M, Biswas K. High-performance thermoelectric energy conversion: A tale of atomic ordering in AgSbTe2. <i>ACS Energy Letters</i>. 2021;6(8):2825-2837. doi:<a href=\"https://doi.org/10.1021/acsenergylett.1c01184\">10.1021/acsenergylett.1c01184</a>"},"doi":"10.1021/acsenergylett.1c01184","_id":"15265","oa_version":"None","quality_controlled":"1"},{"file_date_updated":"2024-04-29T06:51:59Z","publication_identifier":{"issn":["1932-6203"]},"article_type":"original","day":"08","external_id":{"pmid":["33831039"]},"author":[{"last_name":"Overdijk","first_name":"Elysa J. R.","full_name":"Overdijk, Elysa J. R."},{"full_name":"Putker, Vera","first_name":"Vera","last_name":"Putker"},{"last_name":"Smits","first_name":"Joep","full_name":"Smits, Joep"},{"full_name":"Tang, Han","id":"19BDF720-25A0-11EA-AC6E-928F3DDC885E","last_name":"Tang","orcid":"0000-0001-6152-6637","first_name":"Han"},{"full_name":"Bouwmeester, Klaas","last_name":"Bouwmeester","first_name":"Klaas"},{"last_name":"Govers","first_name":"Francine","full_name":"Govers, Francine"},{"last_name":"Ketelaar","first_name":"Tijs","full_name":"Ketelaar, Tijs"}],"date_updated":"2024-04-29T06:53:15Z","title":"Phytophthora infestans RXLR effector AVR1 disturbs the growth of Physcomitrium patens without affecting Sec5 localization","department":[{"_id":"JiFr"}],"volume":16,"doi":"10.1371/journal.pone.0249637","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"ista":"Overdijk EJR, Putker V, Smits J, Tang H, Bouwmeester K, Govers F, Ketelaar T. 2021. Phytophthora infestans RXLR effector AVR1 disturbs the growth of Physcomitrium patens without affecting Sec5 localization. PLoS One. 16(4), e0249637.","apa":"Overdijk, E. J. R., Putker, V., Smits, J., Tang, H., Bouwmeester, K., Govers, F., &#38; Ketelaar, T. (2021). Phytophthora infestans RXLR effector AVR1 disturbs the growth of Physcomitrium patens without affecting Sec5 localization. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0249637\">https://doi.org/10.1371/journal.pone.0249637</a>","ama":"Overdijk EJR, Putker V, Smits J, et al. Phytophthora infestans RXLR effector AVR1 disturbs the growth of Physcomitrium patens without affecting Sec5 localization. <i>PLoS One</i>. 2021;16(4). doi:<a href=\"https://doi.org/10.1371/journal.pone.0249637\">10.1371/journal.pone.0249637</a>","mla":"Overdijk, Elysa J. R., et al. “Phytophthora Infestans RXLR Effector AVR1 Disturbs the Growth of Physcomitrium Patens without Affecting Sec5 Localization.” <i>PLoS One</i>, vol. 16, no. 4, e0249637, Public Library of Science, 2021, doi:<a href=\"https://doi.org/10.1371/journal.pone.0249637\">10.1371/journal.pone.0249637</a>.","ieee":"E. J. R. Overdijk <i>et al.</i>, “Phytophthora infestans RXLR effector AVR1 disturbs the growth of Physcomitrium patens without affecting Sec5 localization,” <i>PLoS One</i>, vol. 16, no. 4. Public Library of Science, 2021.","short":"E.J.R. Overdijk, V. Putker, J. Smits, H. Tang, K. Bouwmeester, F. Govers, T. Ketelaar, PLoS One 16 (2021).","chicago":"Overdijk, Elysa J. R., Vera Putker, Joep Smits, Han Tang, Klaas Bouwmeester, Francine Govers, and Tijs Ketelaar. “Phytophthora Infestans RXLR Effector AVR1 Disturbs the Growth of Physcomitrium Patens without Affecting Sec5 Localization.” <i>PLoS One</i>. Public Library of Science, 2021. <a href=\"https://doi.org/10.1371/journal.pone.0249637\">https://doi.org/10.1371/journal.pone.0249637</a>."},"_id":"15266","oa_version":"Published Version","quality_controlled":"1","type":"journal_article","oa":1,"keyword":["Multidisciplinary"],"article_processing_charge":"Yes","year":"2021","publication_status":"published","file":[{"access_level":"open_access","content_type":"application/pdf","file_size":4738995,"checksum":"25b7b329435af57db2c95571a8ef32fe","file_name":"2021_PlosOne_Overdijk.pdf","creator":"dernst","date_created":"2024-04-29T06:51:59Z","relation":"main_file","date_updated":"2024-04-29T06:51:59Z","file_id":"15349","success":1}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e0249637","date_published":"2021-04-08T00:00:00Z","date_created":"2024-04-03T07:38:14Z","has_accepted_license":"1","pmid":1,"abstract":[{"lang":"eng","text":"Plant pathogens often exploit a whole range of effectors to facilitate infection. The RXLR effector AVR1 produced by the oomycete plant pathogen Phytophthora infestans suppresses host defense by targeting Sec5. Sec5 is a subunit of the exocyst, a protein complex that is important for mediating polarized exocytosis during plant development and defense against pathogens. The mechanism by which AVR1 manipulates Sec5 functioning is unknown. In this study, we analyzed the effect of AVR1 on Sec5 localization and functioning in the moss Physcomitrium patens. P. patens has four Sec5 homologs. Two (PpSec5b and PpSec5d) were found to interact with AVR1 in yeast-two-hybrid assays while none of the four showed a positive interaction with AVR1ΔT, a truncated version of AVR1. In P. patens lines carrying β-estradiol inducible AVR1 or AVR1ΔT transgenes, expression of AVR1 or AVR1ΔT caused defects in the development of caulonemal protonema cells and abnormal morphology of chloronema cells. Similar phenotypes were observed in Sec5- or Sec6-silenced P. patens lines, suggesting that both AVR1 and AVR1ΔT affect exocyst functioning in P. patens. With respect to Sec5 localization we found no differences between β-estradiol-treated and untreated transgenic AVR1 lines. Sec5 localizes at the plasma membrane in growing caulonema cells, also during pathogen attack, and its subcellular localization is the same, with or without AVR1 in the vicinity."}],"publisher":"Public Library of Science","language":[{"iso":"eng"}],"intvolume":"        16","issue":"4","publication":"PLoS One","month":"04","ddc":["580"],"status":"public"}]