[{"publication_identifier":{"issn":["1476-1122"],"eissn":["1476-4660"]},"quality_controlled":"1","doi":"10.1038/s41563-026-02517-6","researchdata_availability":"upon request","year":"2026","oa_version":"Preprint","article_type":"original","publication":"Nature Materials","date_published":"2026-06-01T00:00:00Z","volume":25,"OA_type":"green","intvolume":"        25","das_tickbox":"1","abstract":[{"text":"Quantum control of the many-body wavefunction is a central challenge in quantum materials research, as it could yield a precise control knob to manipulate emergent phenomena. Floquet engineering, the coherent dressing of quantum states with periodic non-resonant optical fields, has become an important strategy for quantum control. Most applications to solid-state systems have targeted weakly interacting or single-ion states, leaving the manipulation of many-body wavefunctions largely unexplored. Here we use Floquet engineering to achieve quantum control of a strongly correlated Hubbard exciton in the one-dimensional Mott insulator Sr2CuO3. A non-resonant mid-infrared optical field coherently dresses the exciton wavefunction, driving its rotation between bright and dark states. We use resonant third-harmonic generation to quantify ultrafast π/2 rotations on the Bloch sphere spanned by these exciton states. Our work advances the quest towards programmable control of correlated states and exciton-based quantum sensing.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2601.20695"}],"publisher":"Springer Nature","language":[{"iso":"eng"}],"article_processing_charge":"No","page":"937-943","month":"06","type":"journal_article","status":"public","department":[{"_id":"DeBa"}],"external_id":{"arxiv":["2601.20695 "]},"date_created":"2026-04-12T22:01:53Z","related_material":{"link":[{"url":"https://doi.org/10.1038/s41563-026-02697-1","relation":"erratum"}]},"publication_status":"published","author":[{"full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","first_name":"Denitsa Rangelova","orcid":"0000-0002-7438-1139","id":"71b4d059-2a03-11ee-914d-dfa3beed6530"},{"full_name":"Carmichael, Deven","last_name":"Carmichael","first_name":"Deven"},{"first_name":"Clara S.","last_name":"Weber","full_name":"Weber, Clara S."},{"last_name":"Lu","first_name":"I. Te","full_name":"Lu, I. Te"},{"full_name":"Glerean, Filippo","first_name":"Filippo","last_name":"Glerean"},{"full_name":"Meng, Tepie","first_name":"Tepie","last_name":"Meng"},{"full_name":"De Oliveira, Pedro B.M.","first_name":"Pedro B.M.","last_name":"De Oliveira"},{"full_name":"Homes, Christopher C.","last_name":"Homes","first_name":"Christopher C."},{"full_name":"Zaliznyak, Igor A.","first_name":"Igor A.","last_name":"Zaliznyak"},{"first_name":"G. D.","last_name":"Gu","full_name":"Gu, G. D."},{"full_name":"Dean, Mark P.M.","last_name":"Dean","first_name":"Mark P.M."},{"last_name":"Rubio","first_name":"Angel","full_name":"Rubio, Angel"},{"full_name":"Kennes, Dante M.","last_name":"Kennes","first_name":"Dante M."},{"last_name":"Claassen","first_name":"Martin","full_name":"Claassen, Martin"},{"first_name":"Matteo","last_name":"Mitrano","full_name":"Mitrano, Matteo"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"The data that support the findings of this study are present in the Article and its Supplementary Information. Source data for Figs. 1–4 are available via Figshare at https://doi.org/10.6084/m9.figshare.31146367 (ref. 51). Any additional data are available from the corresponding authors upon request.","acknowledgement":"We thank K. Burch, M. Buzzi, P. Cappellaro, A. Cavalleri, E. Demler, M. Eckstein, T. Giamarchi, D. Hsieh, H. Okamoto, D. Reis, T. Tohyama, P. Werner and A. Yacoby for insightful discussions. We thank B. Baxley for assistance with graphics. This work was primarily supported by the US Department of Energy, Office of Basic Energy Sciences, Early Career Award Program, under award no. DE-SC0022883 (D.R.B., F.G., T.M. and M.M.) and award no. DE-SC0024494 (D.C. and M.C.). D.C. and P.B.M.D.O. acknowledge funding from the NSF GRFP under grant nos. DGE-1845298 and DGE 2140743, respectively. The work performed at Brookhaven National Laboratory was supported by the US Department of Energy, Division of Materials Science, under contract no. DE-SC0012704. We acknowledge funding from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 531215165 (Research Unit “OPTIMAL’). This work was supported by the Cluster of Excellence ‘Advanced Imaging of Matter’ (AIM) and the Max Planck-New York City Center for Non-Equilibrium Quantum Phenomena. The Flatiron Institute is a division of the Simons Foundation. Simulations were performed with computing resources granted by RWTH Aachen University under projects rwth0752 and rwth1258. We acknowledge computing time on the supercomputer JURECA52 at Forschungszentrum Jülich under the project ID enhancerg.","day":"01","scopus_import":"1","_id":"21726","oa":1,"citation":{"ista":"Baykusheva DR, Carmichael D, Weber CS, Lu IT, Glerean F, Meng T, De Oliveira PBM, Homes CC, Zaliznyak IA, Gu GD, Dean MPM, Rubio A, Kennes DM, Claassen M, Mitrano M. 2026. Quantum control of Hubbard excitons. Nature Materials. 25, 937–943.","short":"D.R. Baykusheva, D. Carmichael, C.S. Weber, I.T. Lu, F. Glerean, T. Meng, P.B.M. De Oliveira, C.C. Homes, I.A. Zaliznyak, G.D. Gu, M.P.M. Dean, A. Rubio, D.M. Kennes, M. Claassen, M. Mitrano, Nature Materials 25 (2026) 937–943.","mla":"Baykusheva, Denitsa Rangelova, et al. “Quantum Control of Hubbard Excitons.” <i>Nature Materials</i>, vol. 25, Springer Nature, 2026, pp. 937–43, doi:<a href=\"https://doi.org/10.1038/s41563-026-02517-6\">10.1038/s41563-026-02517-6</a>.","ieee":"D. R. Baykusheva <i>et al.</i>, “Quantum control of Hubbard excitons,” <i>Nature Materials</i>, vol. 25. Springer Nature, pp. 937–943, 2026.","apa":"Baykusheva, D. R., Carmichael, D., Weber, C. S., Lu, I. T., Glerean, F., Meng, T., … Mitrano, M. (2026). Quantum control of Hubbard excitons. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-026-02517-6\">https://doi.org/10.1038/s41563-026-02517-6</a>","ama":"Baykusheva DR, Carmichael D, Weber CS, et al. Quantum control of Hubbard excitons. <i>Nature Materials</i>. 2026;25:937-943. doi:<a href=\"https://doi.org/10.1038/s41563-026-02517-6\">10.1038/s41563-026-02517-6</a>","chicago":"Baykusheva, Denitsa Rangelova, Deven Carmichael, Clara S. Weber, I. Te Lu, Filippo Glerean, Tepie Meng, Pedro B.M. De Oliveira, et al. “Quantum Control of Hubbard Excitons.” <i>Nature Materials</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41563-026-02517-6\">https://doi.org/10.1038/s41563-026-02517-6</a>."},"date_updated":"2026-07-27T12:32:56Z","supplementarymaterial":"yes","corr_author":"1","arxiv":1,"title":"Quantum control of Hubbard excitons","OA_place":"repository"},{"citation":{"ama":"Mondal M, Ghorai P, Samadder A, Freunberger SA, Banerjee P. H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis. <i>Journal of Materials Chemistry B</i>. 2026;14(17):5314-5322. doi:<a href=\"https://doi.org/10.1039/d5tb02687c\">10.1039/d5tb02687c</a>","chicago":"Mondal, Moumita, Pravat Ghorai, Asmita Samadder, Stefan Alexander Freunberger, and Priyabrata Banerjee. “H2O2 Responsive Rhodamine-Based Probe for Monitoring Early-Stage Diabetes Diagnosis.” <i>Journal of Materials Chemistry B</i>. Royal Society of Chemistry, 2026. <a href=\"https://doi.org/10.1039/d5tb02687c\">https://doi.org/10.1039/d5tb02687c</a>.","apa":"Mondal, M., Ghorai, P., Samadder, A., Freunberger, S. A., &#38; Banerjee, P. (2026). H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis. <i>Journal of Materials Chemistry B</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d5tb02687c\">https://doi.org/10.1039/d5tb02687c</a>","ieee":"M. Mondal, P. Ghorai, A. Samadder, S. A. Freunberger, and P. Banerjee, “H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis,” <i>Journal of Materials Chemistry B</i>, vol. 14, no. 17. Royal Society of Chemistry, pp. 5314–5322, 2026.","mla":"Mondal, Moumita, et al. “H2O2 Responsive Rhodamine-Based Probe for Monitoring Early-Stage Diabetes Diagnosis.” <i>Journal of Materials Chemistry B</i>, vol. 14, no. 17, Royal Society of Chemistry, 2026, pp. 5314–22, doi:<a href=\"https://doi.org/10.1039/d5tb02687c\">10.1039/d5tb02687c</a>.","ista":"Mondal M, Ghorai P, Samadder A, Freunberger SA, Banerjee P. 2026. H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis. Journal of Materials Chemistry B. 14(17), 5314–5322.","short":"M. Mondal, P. Ghorai, A. Samadder, S.A. Freunberger, P. Banerjee, Journal of Materials Chemistry B 14 (2026) 5314–5322."},"date_updated":"2026-07-27T12:36:05Z","supplementarymaterial":"yes","corr_author":"1","title":"H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis","issue":"17","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"MM acknowledges the Government of India for DST-INSPIRE\r\nfellowship [IF200389] and Federal Ministry of Education, Science and Research (BMBWF) and the OeAD – Austria’s Agency for Education and Internationalisation for an Ernst Mach Grant, weltweit (grant number MPC-2024-01518) for research internship at ISTA. The Scientific Service Units of ISTA supported this research through resources provided by the Lab Support Facility. PG acknowledges the ANRF, India, for his NPDF fellowship (File no. PDF/2022/001960). PB acknowledges ANRF, India, for the SERB-CRG sponsored project GAP-240712 (vide reference no. CRG/2022/001679).","dataavailabilitystatement":"The data supporting this article have been included as part of the supplementary information (SI). The supplementary information includes all spectral profiles, plots and tabulated data. See DOI: https://doi.org/10.1039/d5tb02687c.","day":"06","scopus_import":"1","_id":"21730","department":[{"_id":"StFr"}],"external_id":{"pmid":["41958432"]},"date_created":"2026-04-13T07:45:26Z","publication_status":"published","pmid":1,"author":[{"full_name":"Mondal, Moumita","first_name":"Moumita","last_name":"Mondal"},{"full_name":"Ghorai, Pravat","first_name":"Pravat","last_name":"Ghorai"},{"last_name":"Samadder","first_name":"Asmita","full_name":"Samadder, Asmita"},{"full_name":"Freunberger, Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","last_name":"Freunberger"},{"last_name":"Banerjee","first_name":"Priyabrata","full_name":"Banerjee, Priyabrata"}],"page":"5314-5322","month":"05","type":"journal_article","status":"public","abstract":[{"text":"Hydrogen peroxide (H2O2) is a crucial member of the reactive oxygen species (ROS) family, playing roles in cellular signalling and immune responses in human health. Moreover, it is a potential biomarker of diabetes when present in aberrant concentrations. Therefore, monitoring trace levels of H2O2 has become a research hotspot for analytical and sensor chemists. In this context, we report a rhodamine-based fluorescent probe (RN), which shows excellent fluorescent enhancement at 555 nm upon the addition of H2O2 along with a low limit of detection (LOD) of 0.67 ppm and fast response (∼2 min). The probe is highly selective for H2O2, showing no fluorescence enhancement with other ROS. RN is synthesised in a one-pot chemical reaction using rhodamine 6G (R6G) and 4,7,10-trioxa-1,13-tridecanediamine (TTDA). H2O2 detection in pre-treated milk samples proves its real-world viability. We found that RN shows low cytotoxicity, which allowed us to successfully explore its potential to monitor H2O2 generation in a diabetic L929 skin cell line and diabetic mice liver tissue. This result demonstrates promising features for assessing early diabetic progression through fluorescence imaging.","lang":"eng"}],"publisher":"Royal Society of Chemistry","language":[{"iso":"eng"}],"article_processing_charge":"No","date_published":"2026-05-06T00:00:00Z","publication":"Journal of Materials Chemistry B","volume":14,"OA_type":"closed access","intvolume":"        14","das_tickbox":"1","researchdata_availability":"yes","year":"2026","oa_version":"None","article_type":"original","publication_identifier":{"issn":["2050-750X"],"eissn":["2050-7518"]},"acknowledged_ssus":[{"_id":"LifeSc"}],"quality_controlled":"1","doi":"10.1039/d5tb02687c"},{"publication_identifier":{"issn":["2663-337X"]},"has_accepted_license":"1","doi":"10.15479/AT-ISTA-21854","acknowledged_ssus":[{"_id":"ScienComp"}],"year":"2026","ddc":["000"],"oa_version":"Published Version","doi_confirm":"1","date_published":"2026-05-11T00:00:00Z","das_tickbox":"1","publisher":"Institute of Science and Technology Austria","abstract":[{"lang":"eng","text":"As neural-network-based models grow both in size and popularity, interest has grown in making the models smaller and more efficient to train. To that end, many methods have been proposed to prune models by reducing their number of nonzero parameters. Additionally, parameter-efficient fine-tuning, in which a much smaller number of parameters than the total contained in the model is updated during training, has become very popular, especially in the space of Large Language Models. At the same time, the increasingly routine deployment of machine learning in real-world applications has spurred a drive to make them more trustworthy - in the sense of, among other things, being unbiased, interpretable, and editable. In this thesis, we examine the interplay between efficiency and trustworthiness.\r\n\r\nFirst, we analyze the effects of model pruning on bias in computer vision models, demonstrating that increased sparsity leads to greater bias, largely as a function of increased model uncertainty in marginal cases. Based on this observation, we propose several bias mitigation techniques. Then, we demonstrate that example-specific model pruning can improve model interpretation methods while improving pruning efficiency to make example-specific model pruning feasible in real time. Then, we investigate the effectiveness of parameter-efficient and data-efficient model personalization via fine-tuning, demonstrating that it is highly feasible with very small computational and data resources. Finally, we consider efficiency in editing model knowledge using a custom synthetic data framework, demonstrating that parameter-efficient, low-rank fine-tuning frequently outperforms full-rank fine-tuning, and, additionally, that restricting which model blocks are fine-tuned frequently improves results. Together, the results in this thesis provide new insights and techniques for combining trustworthiness and efficiency during neural network inference and training.\r\n\r\n"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"type":"dissertation","month":"05","page":"237","file":[{"file_name":"EIofinova_thesis_FinalVersion.zip","date_created":"2026-05-11T08:36:01Z","date_updated":"2026-05-11T08:36:01Z","access_level":"closed","relation":"source_file","creator":"eiofinov","file_size":28479571,"content_type":"application/zip","checksum":"2e148dad920e3f9b7c32796e0ba2e5f7","file_id":"21856"},{"access_level":"open_access","relation":"main_file","file_name":"2026_Iofinova_Eugenia_Thesis.pdf","date_created":"2026-05-13T13:10:48Z","date_updated":"2026-05-13T13:10:48Z","creator":"eiofinov","success":1,"file_id":"21877","checksum":"b10c2933f386f532b2dbf28b19c5525c","file_size":18137757,"content_type":"application/pdf"}],"alternative_title":["ISTA Thesis"],"degree_awarded":"PhD","status":"public","date_created":"2026-05-11T08:43:22Z","department":[{"_id":"GradSch"},{"_id":"DaAl"}],"author":[{"full_name":"Iofinova, Eugenia B","first_name":"Eugenia B","orcid":"0000-0002-7778-3221","last_name":"Iofinova","id":"f9a17499-f6e0-11ea-865d-fdf9a3f77117"}],"publication_status":"published","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"14771"},{"relation":"part_of_dissertation","status":"public","id":"18121"},{"id":"21858","status":"public","relation":"part_of_dissertation"},{"id":"21859","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"21857","status":"public"}]},"day":"11","acknowledgement":"The research in this Ph.D. was funded in whole\r\nor in part by the Austrian Science Fund (FWF) W1260-N35 (Vienna Graduate School for\r\nComputational Optimization). For open access purposes the author has applied a CC BY\r\npublic copyright license to any author accepted manuscript version arising from this submission\r\nwherever possible. Additionally, I am grateful to Alois Schlögl, Waleed Khalid, and the rest of\r\nthe ISTA Scientific Computing team for building and maintaining the infrastructure I used\r\nto run experiments. I’m also deeply grateful to the Alistarh group’s administrative assistant,\r\nChristine Francois, who always deals with our nonsense with common sense and a smile.\r\n","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","_id":"21854","file_date_updated":"2026-05-13T13:10:48Z","supervisor":[{"full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian","last_name":"Alistarh"}],"date_updated":"2026-07-27T12:50:04Z","project":[{"grant_number":"W1260-N35","name":"Vienna Graduate School on Computational Optimization","_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A"}],"citation":{"mla":"Iofinova, Eugenia B. <i>On the Utility and Effects of Efficiency in Artificial Neural Networks</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21854\">10.15479/AT-ISTA-21854</a>.","ieee":"E. B. Iofinova, “On the utility and effects of efficiency in artificial neural networks,” Institute of Science and Technology Austria, 2026.","short":"E.B. Iofinova, On the Utility and Effects of Efficiency in Artificial Neural Networks, Institute of Science and Technology Austria, 2026.","ista":"Iofinova EB. 2026. On the utility and effects of efficiency in artificial neural networks. Institute of Science and Technology Austria.","ama":"Iofinova EB. On the utility and effects of efficiency in artificial neural networks. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21854\">10.15479/AT-ISTA-21854</a>","chicago":"Iofinova, Eugenia B. “On the Utility and Effects of Efficiency in Artificial Neural Networks.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21854\">https://doi.org/10.15479/AT-ISTA-21854</a>.","apa":"Iofinova, E. B. (2026). <i>On the utility and effects of efficiency in artificial neural networks</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21854\">https://doi.org/10.15479/AT-ISTA-21854</a>"},"oa":1,"OA_place":"publisher","title":"On the utility and effects of efficiency in artificial neural networks","publisher_comment":"In reference to IEEE copyrighted material which is used with permission in this thesis, the IEEE does not endorse any of ISTA's products or services. Internal or personal use of this material is permitted. If interested in reprinting/republishing IEEE copyrighted material for advertising or promotional purposes or for creating new collective works for resale or redistribution, please go to http://www.ieee.org/publications_standards/publications/rights/rights_link.html to learn how to obtain a License from RightsLink. If applicable, University Microfilms and/or ProQuest Library, or the Archives of Canada may supply single copies of the dissertation.","corr_author":"1"},{"OA_type":"green","publication":"Third Conference on Parsimony and Learning (Proceedings Track)","date_published":"2026-03-06T00:00:00Z","language":[{"iso":"eng"}],"article_processing_charge":"No","publisher":"OpenReview","main_file_link":[{"open_access":"1","url":"https://openreview.net/pdf?id=soFWnTqd23"}],"abstract":[{"text":"The availability of powerful open-source large language models (LLMs) opens exciting use cases, such as using personal data to fine-tune these models to imitate a user’s unique writing style. Two key requirements for this functionality are personalization–in the sense that the output should recognizably reflect the user’s own writing style—and privacy–users may justifiably be wary of uploading extremely personal data, such as their email archive, to a third-party service. In this paper, we demonstrate the feasibility of training and running such an assistant, which we call Panza, on commodity hardware, for the specific use case of email generation. Panza’s personalization features are based on a combination of parameter-efficient fine-tuning using a variant of the Reverse Instructions technique [1] and Retrieval-Augmented Generation (RAG) [2]. We demonstrate that this combination allows us to fine-tune an LLM to reflect a user’s writing style using limited data, while executing on extremely limited resources, e.g. on a free Google Colab instance. Our key methodological contribution is the first detailed study of evaluation metrics for this task, and\r\nof how different choices of system components–the use of RAG and of different fine-tuning approaches–impact the system’s performance. Additionally, we demonstrate that very little data - under 100 email samples - are sufficient to create models that convincingly imitate humans, showcasing a previously unknown attack vector in language models. We are releasing the full Panza code as well as three new email datasets licensed for research use.","lang":"eng"}],"quality_controlled":"1","conference":{"name":"CPAL: Conference on Parsimony and Learning","start_date":"2026-03-23","location":"Tübíngen, Germany","end_date":"2026-03-26"},"oa_version":"Accepted Version","year":"2026","_id":"21857","day":"06","article_number":"81","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Panza: Investigating the feasibility of fully-local personalized text generation","OA_place":"publisher","corr_author":"1","date_updated":"2026-07-27T12:50:03Z","oa":1,"citation":{"mla":"Nicolicioiu, Armand, et al. “Panza: Investigating the Feasibility of Fully-Local Personalized Text Generation.” <i>Third Conference on Parsimony and Learning (Proceedings Track)</i>, 81, OpenReview, 2026.","ieee":"A. Nicolicioiu <i>et al.</i>, <i>Panza: Investigating the feasibility of fully-local personalized text generation</i>. OpenReview, 2026.","short":"A. Nicolicioiu, E.B. Iofinova, A. Jovanovic, E. Kurtic, M. Nikdan, A. Panferov, I. Markov, N. Shavit, D.-A. Alistarh, Panza: Investigating the Feasibility of Fully-Local Personalized Text Generation, OpenReview, 2026.","ista":"Nicolicioiu A, Iofinova EB, Jovanovic A, Kurtic E, Nikdan M, Panferov A, Markov I, Shavit N, Alistarh D-A. 2026. Panza: Investigating the feasibility of fully-local personalized text generation, OpenReview,p.","chicago":"Nicolicioiu, Armand, Eugenia B Iofinova, Andrej Jovanovic, Eldar Kurtic, Mahdi Nikdan, Andrei Panferov, Ilia Markov, Nir Shavit, and Dan-Adrian Alistarh. <i>Panza: Investigating the Feasibility of Fully-Local Personalized Text Generation</i>. <i>Third Conference on Parsimony and Learning (Proceedings Track)</i>. OpenReview, 2026.","ama":"Nicolicioiu A, Iofinova EB, Jovanovic A, et al. <i>Panza: Investigating the Feasibility of Fully-Local Personalized Text Generation</i>. OpenReview; 2026.","apa":"Nicolicioiu, A., Iofinova, E. B., Jovanovic, A., Kurtic, E., Nikdan, M., Panferov, A., … Alistarh, D.-A. (2026). <i>Panza: Investigating the feasibility of fully-local personalized text generation</i>. <i>Third Conference on Parsimony and Learning (Proceedings Track)</i>. Tübíngen, Germany: OpenReview."},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","keyword":["LLMs","PEFT","LoRA","personalization","efficient ML"],"type":"conference_poster","month":"03","author":[{"full_name":"Nicolicioiu, Armand","last_name":"Nicolicioiu","first_name":"Armand"},{"orcid":"0000-0002-7778-3221","first_name":"Eugenia B","last_name":"Iofinova","id":"f9a17499-f6e0-11ea-865d-fdf9a3f77117","full_name":"Iofinova, Eugenia B"},{"full_name":"Jovanovic, Andrej","last_name":"Jovanovic","first_name":"Andrej"},{"last_name":"Kurtic","first_name":"Eldar","id":"47beb3a5-07b5-11eb-9b87-b108ec578218","full_name":"Kurtic, Eldar"},{"full_name":"Nikdan, Mahdi","id":"66374281-f394-11eb-9cf6-869147deecc0","last_name":"Nikdan","first_name":"Mahdi"},{"id":"2c18daae-4dbe-11ef-8491-98ce2d960f09","first_name":"Andrei","last_name":"Panferov","full_name":"Panferov, Andrei"},{"full_name":"Markov, Ilia","id":"D0CF4148-C985-11E9-8066-0BDEE5697425","last_name":"Markov","first_name":"Ilia"},{"full_name":"Shavit, Nir","first_name":"Nir","last_name":"Shavit"},{"full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh"}],"related_material":{"record":[{"relation":"dissertation_contains","id":"21854","status":"public"}]},"publication_status":"published","date_created":"2026-05-11T08:50:28Z","department":[{"_id":"GradSch"},{"_id":"DaAl"}]},{"title":"Behemoth: Benchmarking unlearning in LLMs using fully synthetic data","OA_place":"repository","corr_author":"1","arxiv":1,"date_updated":"2026-07-27T12:50:03Z","citation":{"short":"E.B. Iofinova, D.-A. Alistarh, ArXiv (n.d.).","ista":"Iofinova EB, Alistarh D-A. Behemoth: Benchmarking unlearning in LLMs using fully synthetic data. arXiv, <a href=\"https://doi.org/10.48550/arXiv.2601.23153\">10.48550/arXiv.2601.23153</a>.","mla":"Iofinova, Eugenia B., and Dan-Adrian Alistarh. “Behemoth: Benchmarking Unlearning in LLMs Using Fully Synthetic Data.” <i>ArXiv</i>, doi:<a href=\"https://doi.org/10.48550/arXiv.2601.23153\">10.48550/arXiv.2601.23153</a>.","ieee":"E. B. Iofinova and D.-A. Alistarh, “Behemoth: Benchmarking unlearning in LLMs using fully synthetic data,” <i>arXiv</i>. .","apa":"Iofinova, E. B., &#38; Alistarh, D.-A. (n.d.). Behemoth: Benchmarking unlearning in LLMs using fully synthetic data. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2601.23153\">https://doi.org/10.48550/arXiv.2601.23153</a>","ama":"Iofinova EB, Alistarh D-A. Behemoth: Benchmarking unlearning in LLMs using fully synthetic data. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2601.23153\">10.48550/arXiv.2601.23153</a>","chicago":"Iofinova, Eugenia B, and Dan-Adrian Alistarh. “Behemoth: Benchmarking Unlearning in LLMs Using Fully Synthetic Data.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2601.23153\">https://doi.org/10.48550/arXiv.2601.23153</a>."},"oa":1,"project":[{"name":"Vienna Graduate School on Computational Optimization","grant_number":"W1260-N35","_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A"}],"_id":"21859","acknowledgement":"EI thanks Weiwei Yang, Janardhan Kulkani, and Kate Lytvynets for their advice and support in\r\ndeveloping an earlier version of the Behemoth library. This research was supported by the Scientific\r\nService Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp).\r\nEI was supported in part by the FWF DK VGSCO, grant agreement number W1260-N35.\r\n","day":"30","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"orcid":"0000-0002-7778-3221","first_name":"Eugenia B","last_name":"Iofinova","id":"f9a17499-f6e0-11ea-865d-fdf9a3f77117","full_name":"Iofinova, Eugenia B"},{"full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","last_name":"Alistarh"}],"related_material":{"record":[{"relation":"dissertation_contains","id":"21854","status":"public"}]},"publication_status":"draft","date_created":"2026-05-11T08:58:07Z","external_id":{"arxiv":["2601.23153"]},"department":[{"_id":"GradSch"},{"_id":"DaAl"}],"status":"public","month":"01","type":"preprint","language":[{"iso":"eng"}],"article_processing_charge":"No","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2601.23153","open_access":"1"}],"abstract":[{"text":"As artificial neural networks, and specifically large language models, have improved rapidly in capabilities and quality, they have increasingly been deployed in real-world applications, from customer service to Google search, despite the fact that they frequently make factually incorrect or undesirable statements. This trend has inspired practical and academic interest in model editing, that is, in adjusting the weights of the model to modify its likely outputs for queries relating to a specific fact or set of facts. This may be done either to amend a fact or set of facts, for instance, to fix a frequent error in the training data, or to suppress a fact or set of facts entirely, for instance, in case of dangerous knowledge. Multiple methods have been proposed to do such edits. However, at the same time, it has been shown that such model editing can be brittle and incomplete. Moreover the effectiveness of any model editing method necessarily depends on the data on which the model is trained, and, therefore, a good understanding of the interaction of the training data distribution and the way it is stored in the network is necessary and helpful to reliably perform model editing. However, working with large language models trained on real-world data does not allow us to understand this relationship or fully measure the effects of model editing. We therefore propose Behemoth, a fully synthetic data generation framework. To demonstrate the practical insights from the framework, we explore model editing in the context of simple tabular data, demonstrating surprising findings that, in some cases, echo real-world results, for instance, that in some cases restricting the update rank results in a more effective update.","lang":"eng"}],"OA_type":"green","publication":"arXiv","date_published":"2026-01-30T00:00:00Z","oa_version":"Preprint","year":"2026","acknowledged_ssus":[{"_id":"ScienComp"}],"doi":"10.48550/arXiv.2601.23153"},{"has_accepted_license":"1","status":"public","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"doi":"10.15479/AT-ISTA-21422","month":"03","type":"research_data","file":[{"relation":"main_file","access_level":"open_access","date_created":"2026-03-11T10:28:34Z","date_updated":"2026-03-11T10:28:34Z","file_name":"MBT_Data_Paper.zip","checksum":"54db0b68f0cf919009317fd3da8f733b","file_id":"21429","success":1,"content_type":"application/zip","file_size":85004,"creator":"vsunko"},{"date_updated":"2026-03-11T10:28:37Z","date_created":"2026-03-11T10:28:37Z","file_name":"README.txt","relation":"main_file","access_level":"open_access","content_type":"text/plain","file_size":2593,"checksum":"df1785b7ada7cd07f76a441ee4f52266","file_id":"21430","success":1,"creator":"vsunko"}],"author":[{"full_name":"Sunko, Veronika","orcid":"0000-0003-2724-3523","first_name":"Veronika","last_name":"Sunko","id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3"}],"oa_version":"Published Version","related_material":{"record":[{"id":"21872","status":"public","relation":"used_in_publication"}]},"date_created":"2026-03-11T07:04:26Z","year":"2026","department":[{"_id":"VeSu"}],"_id":"21422","file_date_updated":"2026-03-11T10:28:37Z","day":"11","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","date_published":"2026-03-11T00:00:00Z","article_processing_charge":"No","OA_place":"repository","title":"Data underpinning \"Magneto-optical Kerr effect in an A-type antiferromagnet\"","corr_author":"1","publisher":"Institute of Science and Technology Austria","date_updated":"2026-07-27T13:59:27Z","citation":{"apa":"Sunko, V. (2026). Data underpinning “Magneto-optical Kerr effect in an A-type antiferromagnet.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21422\">https://doi.org/10.15479/AT-ISTA-21422</a>","chicago":"Sunko, Veronika. “Data Underpinning ‘Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21422\">https://doi.org/10.15479/AT-ISTA-21422</a>.","ama":"Sunko V. Data underpinning “Magneto-optical Kerr effect in an A-type antiferromagnet.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21422\">10.15479/AT-ISTA-21422</a>","ista":"Sunko V. 2026. Data underpinning ‘Magneto-optical Kerr effect in an A-type antiferromagnet’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21422\">10.15479/AT-ISTA-21422</a>.","short":"V. Sunko, (2026).","mla":"Sunko, Veronika. <i>Data Underpinning “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21422\">10.15479/AT-ISTA-21422</a>.","ieee":"V. Sunko, “Data underpinning ‘Magneto-optical Kerr effect in an A-type antiferromagnet.’” Institute of Science and Technology Austria, 2026."},"oa":1},{"intvolume":"        98","OA_type":"hybrid","volume":98,"publication":"Current Opinion in Genetics and Development","date_published":"2026-06-01T00:00:00Z","das_tickbox":"1","publisher":"Elsevier","abstract":[{"lang":"eng","text":"Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences that bind transcription factor (TF) proteins to up- or down-regulate target genes. Decades-long efforts yielded TF-DNA interaction models that predict how strongly an individual TF binds arbitrary DNA sequences and how individual binding events on the CRE combine to affect gene expression. These insights can be synthesized into a global, biophysically realistic, and quantitative genotype-phenotype (GP) map for gene regulation, a ‘holy grail’ for the application of evolutionary theory. A global map provides a rare opportunity to simulate the long-term evolution of regulatory sequences and pose several fundamental questions: How long does it take to evolve CREs de novo? How many non-trivial regulatory functions exist in sequence space? How connected are they? For which regulatory architecture is CRE evolution most rapid and evolvable? In this article, the second of a two-part series, we review the application of evolutionary concepts — epistasis, robustness, evolvability, tunability, plasticity, and bet-hedging — to the evolution of gene regulatory sequences. We then evaluate the potential for a unifying theory for the evolution of regulatory sequences and identify key open challenges."}],"article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1879-0380"],"issn":["0959-437X"]},"has_accepted_license":"1","doi":"10.1016/j.gde.2026.102472","quality_controlled":"1","year":"2026","researchdata_availability":"no","article_type":"review","oa_version":"Published Version","ddc":["570"],"article_number":"102472","day":"01","acknowledgement":"We thank Calin Guet and Santiago Herrera-Álvarez for essential contributions to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship, jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science and Technology Austria (ISTA). N.B. acknowledges funding from the ERC Advanced Grant 101055327 “HaplotypeStructure”.\r\nThis study was also supported by the European Molecular Biology Laboratory (N.O.B., J.C.).","dataavailabilitystatement":"No data were used for the research described in the article.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"21759","file_date_updated":"2026-07-27T13:39:59Z","scopus_import":"1","date_updated":"2026-07-27T13:40:24Z","PlanS_conform":"1","project":[{"_id":"bd6958e0-d553-11ed-ba76-86eba6a76c00","grant_number":"101055327","name":"Understanding the evolution of continuous genomes"}],"oa":1,"citation":{"ieee":"E. Mascolo, R. E. Körei, N. O. Borst, N. H. Barton, J. Crocker, and G. Tkačik, “Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges,” <i>Current Opinion in Genetics and Development</i>, vol. 98. Elsevier, 2026.","mla":"Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory and Future Challenges.” <i>Current Opinion in Genetics and Development</i>, vol. 98, 102472, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102472\">10.1016/j.gde.2026.102472</a>.","ista":"Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. 2026. Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. Current Opinion in Genetics and Development. 98, 102472.","short":"E. Mascolo, R.E. Körei, N.O. Borst, N.H. Barton, J. Crocker, G. Tkačik, Current Opinion in Genetics and Development 98 (2026).","ama":"Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. <i>Current Opinion in Genetics and Development</i>. 2026;98. doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102472\">10.1016/j.gde.2026.102472</a>","chicago":"Mascolo, Elia, Reka E Körei, Noa O. Borst, Nicholas H Barton, Justin Crocker, and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory and Future Challenges.” <i>Current Opinion in Genetics and Development</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.gde.2026.102472\">https://doi.org/10.1016/j.gde.2026.102472</a>.","apa":"Mascolo, E., Körei, R. E., Borst, N. O., Barton, N. H., Crocker, J., &#38; Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges. <i>Current Opinion in Genetics and Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2026.102472\">https://doi.org/10.1016/j.gde.2026.102472</a>"},"OA_place":"publisher","title":"Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges","supplementarymaterial":"no","corr_author":"1","type":"journal_article","month":"06","file":[{"date_updated":"2026-07-27T13:39:59Z","date_created":"2026-07-27T13:39:59Z","file_name":"2026_CurrentOpinionGeneticsDev_Mascolo.pdf","relation":"main_file","access_level":"open_access","creator":"dernst","content_type":"application/pdf","file_size":3190001,"success":1,"file_id":"22590","checksum":"ac8bbee61717bfe7116e312cc6825259"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","date_created":"2026-04-26T22:01:46Z","department":[{"_id":"GaTk"},{"_id":"NiBa"}],"author":[{"last_name":"Mascolo","first_name":"Elia","orcid":"0000-0003-2977-7844","id":"776a6ed0-a053-11f0-8635-80b95e0e0d53","full_name":"Mascolo, Elia"},{"id":"50FDE43E-AA30-11E9-A72B-8A12E6697425","first_name":"Reka E","last_name":"Körei","full_name":"Körei, Reka E"},{"last_name":"Borst","first_name":"Noa O.","full_name":"Borst, Noa O."},{"last_name":"Barton","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H"},{"full_name":"Crocker, Justin","first_name":"Justin","last_name":"Crocker"},{"full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gašper","orcid":"0000-0002-6699-1455","last_name":"Tkačik"}],"publication_status":"published"},{"abstract":[{"text":"The development of complex tissues relies on the precise assignment of cell identity. At the molecular scale, this process depends on the deposition of epigenetic modifications—such as methylation—that are regulated by complex biochemical networks and occur at specific regions on the DNA and chromatin. Here we show that despite the complexity of epigenetic regulation, dynamical scaling and self-similarity of DNA methylation marks emerge in embryonic development. Drawing on single-cell multi-omics experiments, super-resolution microscopy and statistical physics, we demonstrate that these phenomena originate in dynamical feedback between DNA methylation and the formation of nanoscale dynamic chromatin aggregates. These nanoscale processes lead to genome-wide increase in DNA methylation marks following a power law and self-similar correlation functions. Using this framework, we identify methylation patterns that precede gene expression changes in embryonic symmetry breaking. Our work identifies linear sequencing measurements as a laboratory to study mesoscopic biophysical processes in vivo.","lang":"eng"}],"publisher":"Springer Nature","article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"ec_funded":1,"volume":22,"publication":"Nature Physics","date_published":"2026-06-01T00:00:00Z","intvolume":"        22","OA_type":"hybrid","das_tickbox":"1","year":"2026","researchdata_availability":"yes","ddc":["570"],"oa_version":"Published Version","article_type":"original","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"doi":"10.1038/s41567-026-03263-x","quality_controlled":"1","has_accepted_license":"1","project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"oa":1,"citation":{"apa":"Olmeda, F., Lohoff, T., Kafetzopoulos, I., Clark, S. J., Benson, L., Santos, F., … Rulands, S. (2026). Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>","chicago":"Olmeda, Fabrizio, Tim Lohoff, Ioannis Kafetzopoulos, Stephen J. Clark, Laura Benson, Fatima Santos, Felix Krueger, Simon Walker, Wolf Reik, and Steffen Rulands. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>.","ama":"Olmeda F, Lohoff T, Kafetzopoulos I, et al. Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. 2026;22:931-940. doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>","ista":"Olmeda F, Lohoff T, Kafetzopoulos I, Clark SJ, Benson L, Santos F, Krueger F, Walker S, Reik W, Rulands S. 2026. Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics. 22, 931–940.","short":"F. Olmeda, T. Lohoff, I. Kafetzopoulos, S.J. Clark, L. Benson, F. Santos, F. Krueger, S. Walker, W. Reik, S. Rulands, Nature Physics 22 (2026) 931–940.","mla":"Olmeda, Fabrizio, et al. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>, vol. 22, Springer Nature, 2026, pp. 931–40, doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>.","ieee":"F. Olmeda <i>et al.</i>, “Scaling and self-similarity in the formation of the embryonic epigenome,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 931–940, 2026."},"date_updated":"2026-07-27T13:56:09Z","PlanS_conform":"1","supplementarymaterial":"yes","OA_place":"publisher","title":"Scaling and self-similarity in the formation of the embryonic epigenome","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","acknowledgement":"We thank all members of the W.R. and S.R. laboratories, F. Piazza, B. D. Simons, and F. Jülicher for helpful discussions. We thank M. Ciarchi for providing annotations for the chromatin compartments. S.R. is a member of the Center for Nano Science (CeNS). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement number 950349). Research in W.R.’s laboratory was supported by the Biotechnology and Biological Sciences Research Council (BB/K010867/1), Wellcome (095645/Z/11/Z) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (EpiCell lineage 882798). F.O. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. Open access funding provided by Max Planck Society.","dataavailabilitystatement":"All sequencing datasets reported in this paper are available on Gene Expression Omnibus (GEO) under accession GSE166226. STORM localization data are available on Zenodo (https://doi.org/10.5281/zenodo.18965309)57. Raw images are available upon request. Code for computing the correlation functions and STORM analysis are available via GitHub at https://github.com/srulands/inference_of_spatio-temporal_processes.","scopus_import":"1","file_date_updated":"2026-07-27T13:54:58Z","_id":"21849","department":[{"_id":"EdHa"}],"external_id":{"pmid":["42318073"]},"date_created":"2026-05-10T22:02:16Z","publication_status":"published","author":[{"id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","last_name":"Olmeda","first_name":"Fabrizio","full_name":"Olmeda, Fabrizio"},{"full_name":"Lohoff, Tim","first_name":"Tim","last_name":"Lohoff"},{"full_name":"Kafetzopoulos, Ioannis","first_name":"Ioannis","last_name":"Kafetzopoulos"},{"full_name":"Clark, Stephen J.","last_name":"Clark","first_name":"Stephen J."},{"first_name":"Laura","last_name":"Benson","full_name":"Benson, Laura"},{"full_name":"Santos, Fatima","last_name":"Santos","first_name":"Fatima"},{"last_name":"Krueger","first_name":"Felix","full_name":"Krueger, Felix"},{"full_name":"Walker, Simon","last_name":"Walker","first_name":"Simon"},{"full_name":"Reik, Wolf","first_name":"Wolf","last_name":"Reik"},{"last_name":"Rulands","first_name":"Steffen","full_name":"Rulands, Steffen"}],"pmid":1,"month":"06","type":"journal_article","page":"931-940","file":[{"creator":"dernst","content_type":"application/pdf","file_size":7932222,"success":1,"file_id":"22591","checksum":"58e7734f1ebaf6def642140cb489f08f","date_updated":"2026-07-27T13:54:58Z","date_created":"2026-07-27T13:54:58Z","file_name":"2026_NaturePhysics_Olmeda.pdf","relation":"main_file","access_level":"open_access"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public"},{"publisher":"Wiley","abstract":[{"text":"Three-dimensional (3D) printing has rapidly developed from a niche hobbyist activity into a widely accessible and indispensable technology across multiple scientific disciplines. Within microscopy, optical engineering laboratories and imaging core facilities, 3D printing enables creating customised solutions for sample holders, optical components and everyday laboratory tools that traditionally required specialised machining. By providing rapid prototyping, low-cost production and reproducibility, 3D printing facilitates innovation and efficiency in facility operations. This article provides a perspective on the possibilities, challenges, and practical aspects of implementing 3D printing within microscopy core facilities. Instead of providing technical review about 3D printing, we focus on service organisation, user engagement, resource management and community-driven repositories for design dissemination. Our aim is to share insights with those considering the implementation of 3D printing as a service for developing add-on components to ease the operation of different aspects of the machine-park driven services and those who are managing advanced instrumentation within research groups.","lang":"eng"}],"article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"intvolume":"       302","OA_type":"hybrid","volume":302,"publication":"Journal of Microscopy","date_published":"2026-06-01T00:00:00Z","das_tickbox":"0","year":"2026","researchdata_availability":"no","article_type":"original","ddc":["600"],"oa_version":"Published Version","publication_identifier":{"eissn":["1365-2818"],"issn":["0022-2720"]},"has_accepted_license":"1","doi":"10.1111/jmi.70106","quality_controlled":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"M-Shop"}],"date_updated":"2026-07-27T14:02:46Z","PlanS_conform":"1","oa":1,"citation":{"chicago":"Goudarzi, Mohammad, Maximilian Schuster, Arthur Milberger, Manuel Gunkel, Stefan Terjung, and Gabriel Krens. “3D Printing in Core Facilities – Low Pain, High Gain.” <i>Journal of Microscopy</i>. Wiley, 2026. <a href=\"https://doi.org/10.1111/jmi.70106\">https://doi.org/10.1111/jmi.70106</a>.","ama":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 3D printing in core facilities – Low pain, high gain. <i>Journal of Microscopy</i>. 2026;302(3):382-395. doi:<a href=\"https://doi.org/10.1111/jmi.70106\">10.1111/jmi.70106</a>","apa":"Goudarzi, M., Schuster, M., Milberger, A., Gunkel, M., Terjung, S., &#38; Krens, G. (2026). 3D printing in core facilities – Low pain, high gain. <i>Journal of Microscopy</i>. Wiley. <a href=\"https://doi.org/10.1111/jmi.70106\">https://doi.org/10.1111/jmi.70106</a>","ieee":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, and G. Krens, “3D printing in core facilities – Low pain, high gain,” <i>Journal of Microscopy</i>, vol. 302, no. 3. Wiley, pp. 382–395, 2026.","mla":"Goudarzi, Mohammad, et al. “3D Printing in Core Facilities – Low Pain, High Gain.” <i>Journal of Microscopy</i>, vol. 302, no. 3, Wiley, 2026, pp. 382–95, doi:<a href=\"https://doi.org/10.1111/jmi.70106\">10.1111/jmi.70106</a>.","ista":"Goudarzi M, Schuster M, Milberger A, Gunkel M, Terjung S, Krens G. 2026. 3D printing in core facilities – Low pain, high gain. Journal of Microscopy. 302(3), 382–395.","short":"M. Goudarzi, M. Schuster, A. Milberger, M. Gunkel, S. Terjung, G. Krens, Journal of Microscopy 302 (2026) 382–395."},"OA_place":"publisher","title":"3D printing in core facilities – Low pain, high gain","corr_author":"1","supplementarymaterial":"no","day":"01","acknowledgement":"This work was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Imaging & Optics Facility (IOF) and the MiBa Machine Shop. Specifically; Robert Hauschild (IOF), sharing designs, insights and pioneering 3D printing activities at the Imaging and Optics Facility; Bernhard Hochreiter (IOF), for support and testing of anoxic chamber. We also thank Ana Rita Carvalho Faria and Oliver Biehlmaier (Biozentrum University of Basel, Imaging Core Facility) for sharing the design of the adopted power meter.\r\nOpen Access funding provided by Institute of Science and Technology Austria.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"3","_id":"21883","file_date_updated":"2026-07-27T14:01:34Z","scopus_import":"1","date_created":"2026-05-17T22:02:11Z","external_id":{"pmid":["42104760"]},"department":[{"_id":"Bio"}],"author":[{"id":"3384113A-F248-11E8-B48F-1D18A9856A87","last_name":"Goudarzi","first_name":"Mohammad","full_name":"Goudarzi, Mohammad"},{"first_name":"Maximilian","last_name":"Schuster","id":"37e65def-d415-11eb-ae59-a7b67be103db","full_name":"Schuster, Maximilian"},{"first_name":"Arthur","last_name":"Milberger","full_name":"Milberger, Arthur"},{"first_name":"Manuel","last_name":"Gunkel","full_name":"Gunkel, Manuel"},{"full_name":"Terjung, Stefan","last_name":"Terjung","first_name":"Stefan"},{"id":"2B819732-F248-11E8-B48F-1D18A9856A87","last_name":"Krens","first_name":"Gabriel","orcid":"0000-0003-4761-5996","full_name":"Krens, Gabriel"}],"pmid":1,"publication_status":"published","type":"journal_article","month":"06","file":[{"file_name":"2026_JourMicroscopy_Goudarzi.pdf","date_updated":"2026-07-27T14:01:34Z","date_created":"2026-07-27T14:01:34Z","access_level":"open_access","relation":"main_file","creator":"dernst","file_size":4625767,"content_type":"application/pdf","checksum":"06dfad92b1465ed614a1201b4129960a","file_id":"22593","success":1}],"page":"382-395","status":"public","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"}},{"publication_identifier":{"eissn":["2041-1723"]},"has_accepted_license":"1","quality_controlled":"1","doi":"10.1038/s41467-026-72577-4","researchdata_availability":"yes","year":"2026","article_type":"original","ddc":["530"],"oa_version":"Published Version","OA_type":"gold","intvolume":"        17","publication":"Nature Communications","date_published":"2026-07-27T00:00:00Z","volume":17,"das_tickbox":"1","publisher":"Springer Nature","abstract":[{"lang":"eng","text":"Magneto-optic Kerr effect (MOKE) is a powerful probe of broken time-reversal symmetry (T), typically used to study ferromagnets. While MOKE has been observed in some antiferromagnets (AFMs) with vanishing magnetization, it is often associated with structures whose symmetry is lower than basic collinear, bipartite order. In contrast, theory predicts a mechanism for MOKE intrinsic to all AFMs of A-type, i.e. layered AFMs in which ferromagnetic layers are antiferromagnetically aligned. Here we report the experimental confirmation of this mechanism in a bulk AFM. We achieve this by measuring the imaginary component of MOKE as a function of photon energy in MnBi2Te4, an A-type AFM where T is preserved in combination with a translation, and comparing the experimental results with model calculations. Our model suggests that observable MOKE should be expected in all collinear A-type AFMs with out-of-plane spin order, thus enabling optical detection of AFM domains and expanding the scope of MOKE to few-layer AFMs."}],"language":[{"iso":"eng"}],"DOAJ_listed":"1","article_processing_charge":"Yes","file":[{"relation":"main_file","access_level":"open_access","date_created":"2026-07-27T13:58:06Z","date_updated":"2026-07-27T13:58:06Z","file_name":"2026_NatureComm_Sunko.pdf","creator":"dernst","success":1,"checksum":"bde19c4342933c05fe801c2bef7dc732","file_id":"22592","content_type":"application/pdf","file_size":1054779}],"month":"07","type":"journal_article","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","external_id":{"arxiv":["2504.16167"]},"date_created":"2026-05-12T21:31:27Z","department":[{"_id":"VeSu"}],"author":[{"last_name":"Sunko","first_name":"Veronika","orcid":"0000-0003-2724-3523","id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3","full_name":"Sunko, Veronika"},{"full_name":"Ahsanullah, Salman","first_name":"Salman","last_name":"Ahsanullah"},{"full_name":"Jain, Vivek","first_name":"Vivek","last_name":"Jain"},{"last_name":"Weber","first_name":"Sophie","full_name":"Weber, Sophie"},{"last_name":"Kumaran","first_name":"Sivaloganathan","full_name":"Kumaran, Sivaloganathan"},{"first_name":"Jiaqiang","last_name":"Yan","full_name":"Yan, Jiaqiang"},{"first_name":"Joseph","last_name":"Orenstein","full_name":"Orenstein, Joseph"},{"full_name":"Ovchinnikov, Dmitry","first_name":"Dmitry","last_name":"Ovchinnikov"}],"related_material":{"record":[{"status":"public","id":"21422","relation":"research_data"}]},"publication_status":"published","dataavailabilitystatement":"The datasets generated and analyzed during the study of “Magneto-optical Kerr effect in an A-type antiferromagnet\" are available in the ISTA REx repository with https://doi.org/10.15479/AT-ISTA-21422.","acknowledgement":"We thank Christine Kuntscher for providing optical conductivity and reflectance data published in ref. 33, and Nicola Spaldin, Joel Moore and Bevin Huang for useful discussions. V.S. and J.O. received support from the Gordon and Betty Moore Foundation’s EPiQS Initiative through Grant GBMF4537 awarded to J.O. at UC Berkeley. Experimental and theoretical work at LBNL and UC Berkeley was funded by the Quantum Materials (KC2202) program under the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract No. DE-AC02-05CH11231. Work at the University of Kansas was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, EPSCoR, and Materials Sciences and Engineering Division under Award No. DE-SC0025319. Parts of device fabrication were performed in the KU Nanofabrication Facility, which is supported by the National Institutes of Health NIGMS P30GM145499. Work at ORNL was supported by the U. S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Sciences and Engineering Division. For the DFT calculations we used resources provided by the Swedish National Infrastructure for Computing (SNIC) at C3SE. We acknowledge support from the US National Science Foundation (NSF) Grant Number 2201516 under the Accelnet program of Office of International Science and Engineering (OISE). This publication is funded in part by a QuantEmX grant from ICAM and the Gordon and Betty Moore Foundation through Grant GBMF9616 to S. K.","day":"27","article_number":"7364","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"21872","file_date_updated":"2026-07-27T13:58:06Z","scopus_import":"1","PlanS_conform":"1","date_updated":"2026-07-27T13:59:27Z","citation":{"apa":"Sunko, V., Ahsanullah, S., Jain, V., Weber, S., Kumaran, S., Yan, J., … Ovchinnikov, D. (2026). Magneto-optical Kerr effect in an A-type antiferromagnet. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-72577-4\">https://doi.org/10.1038/s41467-026-72577-4</a>","chicago":"Sunko, Veronika, Salman Ahsanullah, Vivek Jain, Sophie Weber, Sivaloganathan Kumaran, Jiaqiang Yan, Joseph Orenstein, and Dmitry Ovchinnikov. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-72577-4\">https://doi.org/10.1038/s41467-026-72577-4</a>.","ama":"Sunko V, Ahsanullah S, Jain V, et al. Magneto-optical Kerr effect in an A-type antiferromagnet. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-72577-4\">10.1038/s41467-026-72577-4</a>","short":"V. Sunko, S. Ahsanullah, V. Jain, S. Weber, S. Kumaran, J. Yan, J. Orenstein, D. Ovchinnikov, Nature Communications 17 (2026).","ista":"Sunko V, Ahsanullah S, Jain V, Weber S, Kumaran S, Yan J, Orenstein J, Ovchinnikov D. 2026. Magneto-optical Kerr effect in an A-type antiferromagnet. Nature Communications. 17, 7364.","mla":"Sunko, Veronika, et al. “Magneto-Optical Kerr Effect in an A-Type Antiferromagnet.” <i>Nature Communications</i>, vol. 17, 7364, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-72577-4\">10.1038/s41467-026-72577-4</a>.","ieee":"V. Sunko <i>et al.</i>, “Magneto-optical Kerr effect in an A-type antiferromagnet,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026."},"oa":1,"title":"Magneto-optical Kerr effect in an A-type antiferromagnet","OA_place":"publisher","corr_author":"1","supplementarymaterial":"yes","arxiv":1},{"scopus_import":"1","_id":"21950","issue":"4","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","corr_author":"1","title":"Emerging bioethical conflicts: One Health and animal experimentation","citation":{"short":"Y.I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I.R. Pavone, S. Schober, Alternatives to Laboratory Animals 54 (2026) 226–235.","ista":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. 2026. Emerging bioethical conflicts: One Health and animal experimentation. Alternatives to Laboratory Animals. 54(4), 226–235.","ieee":"Y. I. Ulman, N. Kostomitsopoulos, S. Camenzind, M. Kitsara, I. R. Pavone, and S. Schober, “Emerging bioethical conflicts: One Health and animal experimentation,” <i>Alternatives to Laboratory Animals</i>, vol. 54, no. 4. SAGE Publications, pp. 226–235, 2026.","mla":"Ulman, Yesim Isil, et al. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” <i>Alternatives to Laboratory Animals</i>, vol. 54, no. 4, SAGE Publications, 2026, pp. 226–35, doi:<a href=\"https://doi.org/10.1177/02611929261453330\">10.1177/02611929261453330</a>.","apa":"Ulman, Y. I., Kostomitsopoulos, N., Camenzind, S., Kitsara, M., Pavone, I. R., &#38; Schober, S. (2026). Emerging bioethical conflicts: One Health and animal experimentation. <i>Alternatives to Laboratory Animals</i>. SAGE Publications. <a href=\"https://doi.org/10.1177/02611929261453330\">https://doi.org/10.1177/02611929261453330</a>","chicago":"Ulman, Yesim Isil, Nikos Kostomitsopoulos, Samuel Camenzind, Maria Kitsara, Ilja Richard Pavone, and Sophie Schober. “Emerging Bioethical Conflicts: One Health and Animal Experimentation.” <i>Alternatives to Laboratory Animals</i>. SAGE Publications, 2026. <a href=\"https://doi.org/10.1177/02611929261453330\">https://doi.org/10.1177/02611929261453330</a>.","ama":"Ulman YI, Kostomitsopoulos N, Camenzind S, Kitsara M, Pavone IR, Schober S. Emerging bioethical conflicts: One Health and animal experimentation. <i>Alternatives to Laboratory Animals</i>. 2026;54(4):226-235. doi:<a href=\"https://doi.org/10.1177/02611929261453330\">10.1177/02611929261453330</a>"},"date_updated":"2026-07-27T14:13:17Z","status":"public","page":"226-235","month":"07","type":"journal_article","publication_status":"published","author":[{"full_name":"Ulman, Yesim Isil","first_name":"Yesim Isil","last_name":"Ulman"},{"full_name":"Kostomitsopoulos, Nikos","first_name":"Nikos","last_name":"Kostomitsopoulos"},{"last_name":"Camenzind","first_name":"Samuel","full_name":"Camenzind, Samuel"},{"last_name":"Kitsara","first_name":"Maria","full_name":"Kitsara, Maria"},{"full_name":"Pavone, Ilja Richard","last_name":"Pavone","first_name":"Ilja Richard"},{"id":"80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8","last_name":"Schober","first_name":"Sophie","full_name":"Schober, Sophie"}],"pmid":1,"department":[{"_id":"PreCl"}],"external_id":{"pmid":["42185081"]},"date_created":"2026-06-07T22:01:36Z","das_tickbox":"1","publication":"Alternatives to Laboratory Animals","date_published":"2026-07-01T00:00:00Z","volume":54,"OA_type":"closed access","intvolume":"        54","language":[{"iso":"eng"}],"article_processing_charge":"No","abstract":[{"lang":"eng","text":"One Health initiatives are modern paradigms for research and health care practices in various fields. Concrete definitions of the One Health framework, however, remain heterogeneous, leading to conceptual problems and uncertainties in the application of the framework. This article discusses several approaches to the One Health concept, and their associated consequences, with special focus on animal experimentation. The first issue addressed is how One Health should be defined, as well as what (and who) should be considered within a One Health approach. In order to shed further light on this, we explore the history of animals in biomedical science, highlighting historical milestones in the use of animal models, as well as the development and current state of ethical considerations in the field of animal experimentation. The second issue comes with the inclusion of animal experimentation per se as part of the One Health concept. Therefore, particular attention is paid to bioethical principles and the resulting problems that can arise when applying them to the One Health concept. Arguments such as the idea of inequality between humans and non-human animals, and the premise that all actions are done for the benefit of humans, are raised and then used to explore the question of whether the One Health concept is compatible with existing bioethical principles. Based on the bioethical principles of protecting the environment, the biodiversity and biosphere, this paper seeks an inclusive perspective of the One Health concept. Successful solutions will be based on this concept, which embraces all living beings. The authors conclude that a multispecies ethics approach could help create a more ethical ecosystem that is aligned with the wellbeing of all life on a shared planet."}],"publisher":"SAGE Publications","quality_controlled":"1","doi":"10.1177/02611929261453330","publication_identifier":{"eissn":["2632-3559"],"issn":["0261-1929"]},"oa_version":"None","article_type":"original","year":"2026"},{"quality_controlled":"1","doi":"10.1038/s41559-026-03036-y","publication_identifier":{"eissn":["2397-334X"]},"article_type":"comment","oa_version":"None","researchdata_availability":"no","year":"2026","das_tickbox":"0","OA_type":"closed access","intvolume":"        10","publication":"Nature Ecology & Evolution","date_published":"2026-06-01T00:00:00Z","volume":10,"language":[{"iso":"eng"}],"article_processing_charge":"No","publisher":"Springer Nature","abstract":[{"text":"Individually silencing 125 fruit fly genes reveals opposing fitness effects of mutations between females and males, as well as between germline and somatic tissues.","lang":"eng"}],"status":"public","page":"1035-1036","month":"06","type":"journal_article","author":[{"full_name":"Ruzicka, Filip","id":"347955dd-57b0-11ee-9095-c28bdd368f4b","first_name":"Filip","last_name":"Ruzicka"}],"pmid":1,"publication_status":"published","external_id":{"pmid":["42067637 "]},"date_created":"2026-05-20T14:36:45Z","department":[{"_id":"BeVi"}],"_id":"21900","scopus_import":"1","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Reverse genetics of sexual antagonism","supplementarymaterial":"no","corr_author":"1","date_updated":"2026-07-27T14:05:02Z","citation":{"apa":"Ruzicka, F. (2026). Reverse genetics of sexual antagonism. <i>Nature Ecology &#38; Evolution</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41559-026-03036-y\">https://doi.org/10.1038/s41559-026-03036-y</a>","chicago":"Ruzicka, Filip. “Reverse Genetics of Sexual Antagonism.” <i>Nature Ecology &#38; Evolution</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41559-026-03036-y\">https://doi.org/10.1038/s41559-026-03036-y</a>.","ama":"Ruzicka F. Reverse genetics of sexual antagonism. <i>Nature Ecology &#38; Evolution</i>. 2026;10:1035-1036. doi:<a href=\"https://doi.org/10.1038/s41559-026-03036-y\">10.1038/s41559-026-03036-y</a>","ista":"Ruzicka F. 2026. Reverse genetics of sexual antagonism. Nature Ecology &#38; Evolution. 10, 1035–1036.","short":"F. Ruzicka, Nature Ecology &#38; Evolution 10 (2026) 1035–1036.","ieee":"F. Ruzicka, “Reverse genetics of sexual antagonism,” <i>Nature Ecology &#38; Evolution</i>, vol. 10. Springer Nature, pp. 1035–1036, 2026.","mla":"Ruzicka, Filip. “Reverse Genetics of Sexual Antagonism.” <i>Nature Ecology &#38; Evolution</i>, vol. 10, Springer Nature, 2026, pp. 1035–36, doi:<a href=\"https://doi.org/10.1038/s41559-026-03036-y\">10.1038/s41559-026-03036-y</a>."}},{"OA_place":"publisher","title":"Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames","corr_author":"1","date_updated":"2026-07-27T14:30:42Z","project":[{"_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A","name":"Vienna Graduate School on Computational Optimization","grant_number":"W1260-N35"}],"citation":{"ista":"Zapata J. 2026. Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames. Institute of Science and Technology Austria.","short":"J. Zapata, Overcoming Degeneracy and Singularity: Techniques for Semidefinite Programs and Homotopy Continuation Endgames, Institute of Science and Technology Austria, 2026.","ieee":"J. Zapata, “Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames,” Institute of Science and Technology Austria, 2026.","mla":"Zapata, Jeferson. <i>Overcoming Degeneracy and Singularity: Techniques for Semidefinite Programs and Homotopy Continuation Endgames</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>.","apa":"Zapata, J. (2026). <i>Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>","ama":"Zapata J. Overcoming degeneracy and singularity: Techniques for semidefinite programs and homotopy continuation endgames. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>","chicago":"Zapata, Jeferson. “Overcoming Degeneracy and Singularity: Techniques for Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>."},"oa":1,"_id":"21957","file_date_updated":"2026-06-10T13:33:25Z","supervisor":[{"full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"}],"day":"09","acknowledgement":"Funding: Vienna Graduate School on Computational Optimization (FWF), grant DOI: 10.55776/W1260.","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"id":"00223538-AF8F-11E9-A4C7-F729E6697425","first_name":"Jeferson","last_name":"Zapata","full_name":"Zapata, Jeferson"}],"publication_status":"published","related_material":{"record":[{"relation":"part_of_dissertation","id":"21144","status":"public"}]},"date_created":"2026-06-08T13:29:52Z","department":[{"_id":"GradSch"},{"_id":"VlKo"}],"degree_awarded":"PhD","status":"public","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"type":"dissertation","month":"06","file":[{"file_id":"21958","checksum":"b11a959e99d3dcf61040282b5c837141","content_type":"application/zip","file_size":40811933,"creator":"jzapata","relation":"source_file","access_level":"closed","date_created":"2026-06-08T13:20:02Z","date_updated":"2026-06-08T13:20:02Z","file_name":"istaustriathesis_JZapata.zip"},{"creator":"jzapata","file_size":2207892,"content_type":"application/pdf","success":1,"file_id":"21992","checksum":"edf1e5899b2e31505cd1aa3fe8bd4b7f","file_name":"4_Final_Thesis_JZapata_REX.pdf","date_created":"2026-06-10T13:33:25Z","date_updated":"2026-06-10T13:33:25Z","access_level":"open_access","relation":"main_file"}],"page":"89","alternative_title":["ISTA Thesis"],"article_processing_charge":"No","language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","abstract":[{"text":"This thesis investigates algorithmic certification and approximation methods for degenerate semidefinite programs (SDPs) and the singular roots of polynomial systems. In the first part, we present a hybrid symbolic-numeric algorithm for certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating linear matrix inequalities (LMIs) into a structured polynomial system via facial reduction and incidence varieties, we guarantee the existence of an isolated exact solution. This algebraic reduction enables the certification of maximum-rank numerical approximations using methods from algebraic geometry.\r\n\r\nIn the second part, we address the severe ill-conditioning and loss of quadratic convergence that plague standard path-tracking methods near isolated singular roots. To overcome this, we propose tracking algorithms that achieve superlinear convergence without the computational bloat characteristic of classical deflation techniques. By modeling the solution path as a generalized fractional Puiseux series, our approach combines an explicitly derived algebraic predictor with a localized hyperplane desingularization phase during the corrector step. Furthermore, we introduce a continuous path-limit method and an extension of the geometric sequence rule to directly extract exact fractional exponents. This bypasses traditional heuristic trial-and-error methods and explicitly accommodates sparse series expansions. Numerical experiments confirm that our method significantly reduces the cumulative number of matrix inversions while achieving high-accuracy root approximations, even for heavily degenerate systems exhibiting higher coranks.","lang":"eng"}],"das_tickbox":"1","doi_confirm":"1","date_published":"2026-06-09T00:00:00Z","ddc":["500"],"oa_version":"Published Version","year":"2026","has_accepted_license":"1","doi":"10.15479/AT-ISTA-21957","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-079-4"]}},{"_id":"21360","file_date_updated":"2026-03-02T10:59:50Z","supervisor":[{"full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","orcid":"0000-0002-8510-9739","last_name":"Benková"}],"license":"https://creativecommons.org/licenses/by-sa/4.0/","day":"26","acknowledgement":"I would like to acknowledge the Austrian Academy of Sciences (ÖAW) and European\r\nResearch Executive Agency (REA) for funding my research (DOC ÖAW Fellowship\r\n26130, Horizon Europe BOLERO Project 101060393). ","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","OA_place":"repository","title":"Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species","corr_author":"1","date_updated":"2026-07-27T14:30:08Z","project":[{"grant_number":"101060393","name":"Breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks","_id":"34afa094-11ca-11ed-8bc3-a375845a59fb"}],"citation":{"apa":"Riegler, S. (2026). <i>Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21360\">https://doi.org/10.15479/AT-ISTA-21360</a>","chicago":"Riegler, Stefan. “Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21360\">https://doi.org/10.15479/AT-ISTA-21360</a>.","ama":"Riegler S. Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21360\">10.15479/AT-ISTA-21360</a>","ista":"Riegler S. 2026. Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species. Institute of Science and Technology Austria.","short":"S. Riegler, Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species, Institute of Science and Technology Austria, 2026.","mla":"Riegler, Stefan. <i>Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21360\">10.15479/AT-ISTA-21360</a>.","ieee":"S. Riegler, “Root system plasticity under nutrient limitation: Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea  species,” Institute of Science and Technology Austria, 2026."},"degree_awarded":"PhD","tmp":{"image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)"},"status":"public","month":"02","type":"dissertation","page":"185","file":[{"file_name":"2026_Riegler_Stefan_Thesis.zip","date_updated":"2026-03-02T10:59:50Z","date_created":"2026-03-02T10:59:50Z","access_level":"closed","relation":"source_file","creator":"sriegler","file_size":31430022,"content_type":"application/x-zip-compressed","file_id":"21386","checksum":"2f1f44e8536c2538f94a440217452c9f"},{"date_updated":"2026-03-02T10:59:49Z","date_created":"2026-03-02T10:59:49Z","embargo":"2027-02-27","file_name":"2026_Riegler_Stefan_Thesis.pdf","relation":"main_file","access_level":"closed","content_type":"application/pdf","file_size":11635090,"file_id":"21387","checksum":"2e8dc39640bc26ae5684c944c619719b","embargo_to":"open_access","creator":"sriegler"}],"alternative_title":["ISTA Thesis"],"author":[{"full_name":"Riegler, Stefan","last_name":"Riegler","first_name":"Stefan","orcid":"0000-0003-3413-1343","id":"FF6018E0-D806-11E9-8E43-0B14E6697425"}],"publication_status":"published","related_material":{"record":[{"relation":"research_data","id":"21363","status":"public"}]},"date_created":"2026-02-27T09:08:14Z","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"das_tickbox":"1","doi_confirm":"1","date_published":"2026-02-26T00:00:00Z","article_processing_charge":"No","language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","doi":"10.15479/AT-ISTA-21360","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"publication_identifier":{"issn":["2663-337X"]},"oa_version":"Published Version","ddc":["570","575","583"],"year":"2026"},{"file":[{"file_name":"SupplementaryTables.xlsx","date_updated":"2026-02-27T09:11:33Z","embargo":"2027-02-27","date_created":"2026-02-27T09:11:33Z","access_level":"closed","relation":"main_file","embargo_to":"open_access","creator":"sriegler","file_size":63749444,"content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","checksum":"de9145fa166a28c588b5184a2d3d4fee","file_id":"21364"},{"file_size":124,"content_type":"text/plain","checksum":"ce1f163551c96cee45943a8ea29720b6","file_id":"21365","embargo_to":"open_access","creator":"sriegler","file_name":"ReadMe.txt","embargo":"2027-02-27","date_created":"2026-02-27T09:13:11Z","date_updated":"2026-02-27T09:13:11Z","access_level":"closed","relation":"main_file"}],"month":"02","type":"research_data","status":"public","tmp":{"image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)"},"has_accepted_license":"1","doi":"10.15479/AT-ISTA-21363","date_created":"2026-02-27T09:18:41Z","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"year":"2026","author":[{"last_name":"Riegler","first_name":"Stefan","orcid":"0000-0003-3413-1343","id":"FF6018E0-D806-11E9-8E43-0B14E6697425","full_name":"Riegler, Stefan"}],"ddc":["575"],"related_material":{"record":[{"id":"21360","status":"public","relation":"used_in_publication"}]},"oa_version":"Published Version","day":"27","date_published":"2026-02-27T00:00:00Z","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","_id":"21363","file_date_updated":"2026-02-27T09:13:11Z","publisher":"Institute of Science and Technology Austria","contributor":[{"last_name":"Benková","first_name":"Eva","orcid":"0000-0002-8510-9739","contributor_type":"supervisor","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2026-07-27T14:30:07Z","abstract":[{"lang":"eng","text":"The data contains information on coffee differential gene expression as well as co-expression and trait correlations in two separate experiments. First, contrasting nitrogen supply, second, intra- and interspecific grafting."}],"citation":{"short":"S. Riegler, (2026).","ista":"Riegler S. 2026. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21363\">10.15479/AT-ISTA-21363</a>.","ieee":"S. Riegler, “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species.” Institute of Science and Technology Austria, 2026.","mla":"Riegler, Stefan. <i>Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21363\">10.15479/AT-ISTA-21363</a>.","apa":"Riegler, S. (2026). Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21363\">https://doi.org/10.15479/AT-ISTA-21363</a>","ama":"Riegler S. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21363\">10.15479/AT-ISTA-21363</a>","chicago":"Riegler, Stefan. “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea  Species.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21363\">https://doi.org/10.15479/AT-ISTA-21363</a>."},"title":"Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea  species","article_processing_charge":"No","corr_author":"1"},{"OA_place":"publisher","title":"Exploring protein dynamics using specific labeling approaches for solid-state MAS NMR","corr_author":"1","date_updated":"2026-07-28T06:59:15Z","project":[{"_id":"7be609c4-9f16-11ee-852c-85015ce2b9b0","name":"Exploring protein dynamics by solid-state MAS NMR through specific labeling approaches","grant_number":"26777"}],"oa":1,"citation":{"short":"L.M. Becker, Exploring Protein Dynamics Using Specific Labeling Approaches for Solid-State MAS NMR, Institute of Science and Technology Austria, 2026.","ista":"Becker LM. 2026. Exploring protein dynamics using specific labeling approaches for solid-state MAS NMR. Institute of Science and Technology Austria.","ieee":"L. M. Becker, “Exploring protein dynamics using specific labeling approaches for solid-state MAS NMR,” Institute of Science and Technology Austria, 2026.","mla":"Becker, Lea Marie. <i>Exploring Protein Dynamics Using Specific Labeling Approaches for Solid-State MAS NMR</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22334\">10.15479/AT-ISTA-22334</a>.","apa":"Becker, L. M. (2026). <i>Exploring protein dynamics using specific labeling approaches for solid-state MAS NMR</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22334\">https://doi.org/10.15479/AT-ISTA-22334</a>","ama":"Becker LM. Exploring protein dynamics using specific labeling approaches for solid-state MAS NMR. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22334\">10.15479/AT-ISTA-22334</a>","chicago":"Becker, Lea Marie. “Exploring Protein Dynamics Using Specific Labeling Approaches for Solid-State MAS NMR.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22334\">https://doi.org/10.15479/AT-ISTA-22334</a>."},"_id":"22334","file_date_updated":"2026-07-16T09:17:08Z","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","supervisor":[{"last_name":"Schanda","first_name":"Paul","orcid":"0000-0002-9350-7606","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","full_name":"Schanda, Paul"}],"day":"13","acknowledgement":"During the work on this thesis, I was the recipient of a DOC Fellowship of the Austrian\r\nAcademy of Sciences at the Institute of Science and Technology Austria (grant no. PR10660EAW01).","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"first_name":"Lea Marie","orcid":"0000-0002-6401-5151","last_name":"Becker","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","full_name":"Becker, Lea Marie"}],"publication_status":"published","related_material":{"record":[{"relation":"part_of_dissertation","id":"12675","status":"public"},{"relation":"part_of_dissertation","id":"21777","status":"public"},{"relation":"part_of_dissertation","id":"12114","status":"public"},{"id":"22105","status":"public","relation":"part_of_dissertation"}]},"date_created":"2026-07-14T08:08:51Z","department":[{"_id":"GradSch"},{"_id":"PaSc"}],"degree_awarded":"PhD","status":"public","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"type":"dissertation","month":"07","file":[{"date_updated":"2026-07-16T09:17:08Z","date_created":"2026-07-16T09:17:08Z","file_name":"2026_Becker_Lea_source_files.zip","relation":"source_file","access_level":"closed","creator":"lbecker","content_type":"application/zip","file_size":99472908,"checksum":"8b85114eff543916c0e1445cd2189555","file_id":"22346"},{"creator":"lbecker","content_type":"application/pdf","file_size":74647289,"success":1,"file_id":"22347","checksum":"6c526862bc6dbd1e4c80ecb34580bc58","date_updated":"2026-07-16T09:17:05Z","date_created":"2026-07-16T09:17:05Z","file_name":"2026_Becker_Lea_Thesis.pdf","relation":"main_file","access_level":"open_access"}],"page":"205","alternative_title":["ISTA Thesis"],"article_processing_charge":"No","language":[{"iso":"eng"}],"publisher":"Institute of Science and Technology Austria","abstract":[{"lang":"eng","text":"Characterizing protein dynamics at the atomic level is essential for our understanding of biological mechanisms. Whether it is to facilitate metabolite transport, catalyze reactions, transmit signals, or regulate metabolism – proteins are constantly in motion and sample multiple conformational states to fulfill their function. Nuclear magnetic resonance (NMR) spectroscopy is particularly well suited to elucidate the dynamics of biomolecules on their complex free-energy landscape. In particular, solid-state magic-angle spinning (MAS) NMR enables the study of large molecular assemblies, protein crystals, or insoluble proteins at atomic resolution without an inherent molecular size limitation. MAS NMR experiments to probe protein dynamics are extremely versatile and sensitive to motional timescales from picoseconds to seconds. Over the past decades, technological advances, developments in experimental design, and new isotope-labeling approaches have further expanded the possibilities of this technique and significantly improved the accuracy of the determined motional parameters.\r\nFunctionally important sites of proteins often contain aromatic residues. Their side-chain motions have therefore long served as valuable indicators of mechanistically relevant dynamics in NMR studies. In this thesis, site-specifically labeled aromatic residues act as sensitive reporters for MAS NMR studies of protein dynamics. The first part addresses how different environments impact side-chain motion by probing ring flips of phenylalanines and tyrosines in crystalline proteins and amyloid fibrils. It provides important insights for the analysis of dynamics obtained in non-native protein environments and emphasizes the complex factors that determine the timescale of internal dynamics. In the second part, the focus shifts towards methodological questions regarding the investigation of protein dynamics by 19F MAS NMR. The fluorine nucleus exhibits promising characteristics for NMR studies but also presents significant challenges, which is why the full methodological potential of 19F MAS NMR has not been fully realized yet. This work demonstrates that paramagnetic doping can considerably reduce the measurement time and improve the sensitivity of fluorinated samples. Finally, 19F MAS NMR is evaluated as a tool for studying protein side-chain dynamics on the example of tryptophans. The results illustrate the challenges in analyzing such experiments and lay the foundation for further development of 19F MAS NMR relaxation studies.\r\nTaken together, this thesis highlights the potential of combining specific isotope labeling, MAS NMR, and complementary methods such as crystallography and computational simulations to elucidate internal protein dynamics. The further development of such integrative approaches will be crucial to improving our understanding of complex mechanisms and protein function.\r\n"}],"das_tickbox":"1","doi_confirm":"1","date_published":"2026-07-13T00:00:00Z","oa_version":"Published Version","ddc":["572"],"year":"2026","has_accepted_license":"1","doi":"10.15479/AT-ISTA-22334","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"NMR"}],"publication_identifier":{"isbn":["978-3-99078-084-8"],"issn":["2663-337X"]}},{"researchdata_availability":"yes","year":"2026","ddc":["540"],"oa_version":"Published Version","article_type":"original","publication_identifier":{"eissn":["17554349"],"issn":["17554330"]},"quality_controlled":"1","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"doi":"10.1038/s41557-026-02155-0","has_accepted_license":"1","abstract":[{"text":"Protein conformational energy landscapes are shaped not only by intramolecular interactions but also by their environment. In protein crystals and protein–protein complexes, intermolecular contacts alter this energy landscape, but the exact nature of this alteration is difficult to decipher. Understanding how the crystal lattice affects protein dynamics is crucial for crystallography-based studies of motion, yet its influence on collective motions remains unclear. Aromatic ring flips in the hydrophobic core represent sensitive probes of such dynamics. Here, we compare the kinetics of aromatic ring flips in the protein GB1 in crystals, in complex with its binding partner IgG, and in solution, combining advanced isotope labelling with quantitative NMR methods. We show that rings in the core flip nearly a thousand times less frequently in crystals than in solution. Enhanced-sampling molecular dynamics simulations, based on a crystal structure of a GB1 variant reported in this work, reproduce these elevated barriers and reveal how the crystal restrains motions.","lang":"eng"}],"publisher":"Springer Nature","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","publication":"Nature Chemistry","date_published":"2026-07-01T00:00:00Z","volume":18,"OA_type":"hybrid","intvolume":"        18","das_tickbox":"1","department":[{"_id":"PaSc"},{"_id":"LifeSc"}],"external_id":{"pmid":["42271006"]},"date_created":"2026-06-21T22:03:01Z","related_material":{"record":[{"status":"public","id":"20641","relation":"research_data"},{"id":"21145","status":"public","relation":"research_data"},{"relation":"dissertation_contains","id":"22334","status":"public"}]},"publication_status":"published","pmid":1,"author":[{"last_name":"Becker","orcid":"0000-0002-6401-5151","first_name":"Lea Marie","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","full_name":"Becker, Lea Marie"},{"full_name":"Fu, Haohao","first_name":"Haohao","last_name":"Fu"},{"last_name":"Tatman","first_name":"Benjamin","id":"71cda2f3-e604-11ee-a1df-da10587eda3f","full_name":"Tatman, Benjamin"},{"full_name":"Dreydoppel, Matthias","last_name":"Dreydoppel","first_name":"Matthias"},{"full_name":"Kapitonova, Anna","last_name":"Kapitonova","first_name":"Anna","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471"},{"full_name":"Balazs, Daniel","first_name":"Daniel","orcid":"0000-0001-7597-043X","last_name":"Balazs","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E"},{"last_name":"Weininger","first_name":"Ulrich","full_name":"Weininger, Ulrich"},{"first_name":"Sylvain","last_name":"Engilberge","full_name":"Engilberge, Sylvain"},{"first_name":"Christophe","last_name":"Chipot","full_name":"Chipot, Christophe"},{"last_name":"Schanda","orcid":"0000-0002-9350-7606","first_name":"Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","full_name":"Schanda, Paul"}],"page":"1221-1230","file":[{"file_id":"22595","checksum":"1069fb27949fd2cb641b043b3a96a580","success":1,"content_type":"application/pdf","file_size":2618184,"creator":"dernst","relation":"main_file","access_level":"open_access","date_created":"2026-07-28T06:58:35Z","date_updated":"2026-07-28T06:58:35Z","file_name":"2026_NatureChemistry_Becker.pdf"}],"type":"journal_article","month":"07","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","oa":1,"citation":{"chicago":"Becker, Lea Marie, Haohao Fu, Benjamin Tatman, Matthias Dreydoppel, Anna Kapitonova, Daniel Balazs, Ulrich Weininger, Sylvain Engilberge, Christophe Chipot, and Paul Schanda. “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” <i>Nature Chemistry</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41557-026-02155-0\">https://doi.org/10.1038/s41557-026-02155-0</a>.","ama":"Becker LM, Fu H, Tatman B, et al. Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes. <i>Nature Chemistry</i>. 2026;18:1221-1230. doi:<a href=\"https://doi.org/10.1038/s41557-026-02155-0\">10.1038/s41557-026-02155-0</a>","apa":"Becker, L. M., Fu, H., Tatman, B., Dreydoppel, M., Kapitonova, A., Balazs, D., … Schanda, P. (2026). Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-026-02155-0\">https://doi.org/10.1038/s41557-026-02155-0</a>","mla":"Becker, Lea Marie, et al. “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” <i>Nature Chemistry</i>, vol. 18, Springer Nature, 2026, pp. 1221–30, doi:<a href=\"https://doi.org/10.1038/s41557-026-02155-0\">10.1038/s41557-026-02155-0</a>.","ieee":"L. M. Becker <i>et al.</i>, “Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes,” <i>Nature Chemistry</i>, vol. 18. Springer Nature, pp. 1221–1230, 2026.","short":"L.M. Becker, H. Fu, B. Tatman, M. Dreydoppel, A. Kapitonova, D. Balazs, U. Weininger, S. Engilberge, C. Chipot, P. Schanda, Nature Chemistry 18 (2026) 1221–1230.","ista":"Becker LM, Fu H, Tatman B, Dreydoppel M, Kapitonova A, Balazs D, Weininger U, Engilberge S, Chipot C, Schanda P. 2026. Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes. Nature Chemistry. 18, 1221–1230."},"project":[{"_id":"7be609c4-9f16-11ee-852c-85015ce2b9b0","name":"Exploring protein dynamics by solid-state MAS NMR through specific labeling approaches","grant_number":"26777"}],"PlanS_conform":"1","date_updated":"2026-07-28T06:59:16Z","corr_author":"1","supplementarymaterial":"yes","title":"Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"The cryo and room-temperature crystal structures of GB1QDD are deposited at the PDB under the access codes 9I2I and 9T8Z, respectively. The solid-state NMR backbone assignment of GB1QDD is deposited at the BMRB under the access code 53330. NMR spectra, analysis scripts and raw data are publicly available at the ISTA research explorer (https://doi.org/10.15479/AT-ISTA-20641)120. Files to reproduce the enhanced-sampling MD simulations are publicly available at the ISTA research explorer (https://doi.org/10.15479/AT-ISTA-21145)121.","acknowledgement":"We thank N. R. Skrynnikov and O. O. Lebedenko (St. Petersburg) for insightful discussions and for performing exploratory MD simulations. We are grateful to T. Schubeis (Lyon) for advice on GB1 crystallization and R. Schmid for initial crystallization trials. We thank C. Mueller-Dieckmann for assistance with room-temperature X-ray crystallography data collection on beamline ID30B at the ESRF, which is acknowledged for providing beamtime through its In-House Research programme. We thank S. Falkner for assistance with constructing the structural model of the IgG:GB1 complex. We thank J. Lewandowski for providing feedback on the paper and granting access to backbone relaxation data of IgG:GB1T2Q and GB1T2Q microcrystals. This research was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank P. Rovó and M. V. Falcón for excellent support of the NMR facility. L.M.B. is recipient of a DOC fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (grant number PR10660EAW01). C.C. acknowledges the European Research Council (grant project 101097272 ‘MilliInMicro’) and the Métropole du Grand Nancy (grant project ‘ARC’). BM07-FIP2 is supported by the French ANR PIA3 (France 2030) EquipEx+ project MAGNIFIX under grant agreement ANR-21-ESRE-0011.Open access funding provided by Institute of Science and Technology (IST Austria).","day":"01","scopus_import":"1","file_date_updated":"2026-07-28T06:58:35Z","_id":"22105"},{"_id":"21164","scopus_import":"1","acknowledgement":"Part of this material is based upon work supported by the NSF National Center for Atmospheric Research, which is a major facility sponsored by the National Science Foundation under Cooperative Agreement No. 1852977. Casallas was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. E. D. Freitas thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 313210/2022–5). Silva gratefully acknowledges the financial support from the National Council for Scientific and Technological Development (CNPq), process number 140512/2021–7. P. Lichtig was supported by base funding from the National Commission for Atomic Energy (CNEA, Arg.) and by NSF NCAR. R.Y. Ynoue thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 406728/2022–4). M. A. Franco thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 407752/2023–4). G. M. Pereira thanks the support by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP; Process numbers 2018/07848–9, 2016/18438–0, and 2019/01316–80) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES; Process number 88887.103225/2025–00). M.F. Andrade thanks the support by FAPESP (Process number 2016/18438–0) and CNPQ (Klimapolis INCT).","dataavailabilitystatement":"Scripts available here https://github.com/ibarraespinosa/musica_vein and here https://github.com/atmoschem/vein.","article_number":"5c08400","day":"17","issue":"6","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality","supplementarymaterial":"yes","date_updated":"2026-07-28T07:03:54Z","citation":{"apa":"Ibarra-Espinosa, S., Dias de Freitas, E., Gaubert, B., Lichtig, P., Ropkins, K., da Silva, I., … Brasseur, G. (2026). A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. <i>Environmental Science &#38;amp; Technology</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.est.5c08400\">https://doi.org/10.1021/acs.est.5c08400</a>","ama":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, et al. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. <i>Environmental Science &#38;amp; Technology</i>. 2026;60(6). doi:<a href=\"https://doi.org/10.1021/acs.est.5c08400\">10.1021/acs.est.5c08400</a>","chicago":"Ibarra-Espinosa, Sergio, Edmilson Dias de Freitas, Benjamin Gaubert, Pablo Lichtig, Karl Ropkins, Iara da Silva, Guilherme Martins Pereira, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” <i>Environmental Science &#38;amp; Technology</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.est.5c08400\">https://doi.org/10.1021/acs.est.5c08400</a>.","ista":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, Lichtig P, Ropkins K, da Silva I, Martins Pereira G, Schuch D, Nascimento J, Hoinaski L, Martins LD, Gavidia-Calderón M, Vara-Vela A, Toledo de Almeida Albuquerque T, Ynoue RY, Diez S, Mera Z, Casallas Garcia A, Vallejo F, Diaz V, Pedruzzi R, Abrutzky R, Franco MA, Huneeus N, Jorquera H, Belalcázar-Cerón LC, Rojas NY, de Fatima Andrade M, Emmons L, Brasseur G. 2026. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &#38;amp; Technology. 60(6), 5c08400.","short":"S. Ibarra-Espinosa, E. Dias de Freitas, B. Gaubert, P. Lichtig, K. Ropkins, I. da Silva, G. Martins Pereira, D. Schuch, J. Nascimento, L. Hoinaski, L.D. Martins, M. Gavidia-Calderón, A. Vara-Vela, T. Toledo de Almeida Albuquerque, R.Y. Ynoue, S. Diez, Z. Mera, A. Casallas Garcia, F. Vallejo, V. Diaz, R. Pedruzzi, R. Abrutzky, M.A. Franco, N. Huneeus, H. Jorquera, L.C. Belalcázar-Cerón, N.Y. Rojas, M. de Fatima Andrade, L. Emmons, G. Brasseur, Environmental Science &#38;amp; Technology 60 (2026).","mla":"Ibarra-Espinosa, Sergio, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” <i>Environmental Science &#38;amp; Technology</i>, vol. 60, no. 6, 5c08400, American Chemical Society, 2026, doi:<a href=\"https://doi.org/10.1021/acs.est.5c08400\">10.1021/acs.est.5c08400</a>.","ieee":"S. Ibarra-Espinosa <i>et al.</i>, “A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality,” <i>Environmental Science &#38;amp; Technology</i>, vol. 60, no. 6. American Chemical Society, 2026."},"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"}],"status":"public","month":"02","type":"journal_article","pmid":1,"author":[{"full_name":"Ibarra-Espinosa, Sergio","first_name":"Sergio","last_name":"Ibarra-Espinosa"},{"first_name":"Edmilson","last_name":"Dias de Freitas","full_name":"Dias de Freitas, Edmilson"},{"last_name":"Gaubert","first_name":"Benjamin","full_name":"Gaubert, Benjamin"},{"first_name":"Pablo","last_name":"Lichtig","full_name":"Lichtig, Pablo"},{"full_name":"Ropkins, Karl","last_name":"Ropkins","first_name":"Karl"},{"last_name":"da Silva","first_name":"Iara","full_name":"da Silva, Iara"},{"full_name":"Martins Pereira, Guilherme","last_name":"Martins Pereira","first_name":"Guilherme"},{"full_name":"Schuch, Daniel","last_name":"Schuch","first_name":"Daniel"},{"last_name":"Nascimento","first_name":"Janaina","full_name":"Nascimento, Janaina"},{"last_name":"Hoinaski","first_name":"Leonardo","full_name":"Hoinaski, Leonardo"},{"full_name":"Martins, Leila Droprinchinski","last_name":"Martins","first_name":"Leila Droprinchinski"},{"first_name":"Mario","last_name":"Gavidia-Calderón","full_name":"Gavidia-Calderón, Mario"},{"last_name":"Vara-Vela","first_name":"Angel","full_name":"Vara-Vela, Angel"},{"first_name":"Taciana","last_name":"Toledo de Almeida Albuquerque","full_name":"Toledo de Almeida Albuquerque, Taciana"},{"full_name":"Ynoue, Rita Yuri","last_name":"Ynoue","first_name":"Rita Yuri"},{"full_name":"Diez, Sebastian","last_name":"Diez","first_name":"Sebastian"},{"first_name":"Zamir","last_name":"Mera","full_name":"Mera, Zamir"},{"id":"92081129-2d75-11ef-a48d-b04dd7a2385a","first_name":"Alejandro","orcid":"0000-0002-1988-5035","last_name":"Casallas Garcia","full_name":"Casallas Garcia, Alejandro"},{"full_name":"Vallejo, Fidel","first_name":"Fidel","last_name":"Vallejo"},{"last_name":"Diaz","first_name":"Valeria","full_name":"Diaz, Valeria"},{"full_name":"Pedruzzi, Rizzieri","first_name":"Rizzieri","last_name":"Pedruzzi"},{"last_name":"Abrutzky","first_name":"Rosana","full_name":"Abrutzky, Rosana"},{"first_name":"Marco A.","last_name":"Franco","full_name":"Franco, Marco A."},{"full_name":"Huneeus, Nicolas","first_name":"Nicolas","last_name":"Huneeus"},{"full_name":"Jorquera, Hector","first_name":"Hector","last_name":"Jorquera"},{"last_name":"Belalcázar-Cerón","first_name":"Luis Carlos","full_name":"Belalcázar-Cerón, Luis Carlos"},{"first_name":"Néstor Y.","last_name":"Rojas","full_name":"Rojas, Néstor Y."},{"full_name":"de Fatima Andrade, Maria","last_name":"de Fatima Andrade","first_name":"Maria"},{"last_name":"Emmons","first_name":"Louisa","full_name":"Emmons, Louisa"},{"last_name":"Brasseur","first_name":"Guy","full_name":"Brasseur, Guy"}],"publication_status":"published","date_created":"2026-02-09T06:54:10Z","external_id":{"pmid":["41636708"]},"department":[{"_id":"CaMu"}],"das_tickbox":"1","OA_type":"closed access","intvolume":"        60","date_published":"2026-02-17T00:00:00Z","publication":"Environmental Science &amp; Technology","volume":60,"ec_funded":1,"language":[{"iso":"eng"}],"article_processing_charge":"No","publisher":"American Chemical Society","abstract":[{"lang":"eng","text":"Global emission inventories often fail to capture the complexities of vehicular pollution in regions with unique fuel mixes, such as Brazil’s extensive biofuel use, leading to significant uncertainties in atmospheric modeling. This study presents a century-long (1960–2100) bottom-up vehicular emission inventory for Brazil, leveraging locally derived emission factors. Our estimates reveal substantial discrepancies in magnitude, timing, and speciation of non-CO2 pollutants (CO, NMHC, PM2.5) compared to leading global inventories (EDGAR, CEDS, CAMS), highlighting critical inaccuracies in widely used data sets. More critically, future projections under Shared Socioeconomic Pathways (SSPs) uncover a novel positive feedback mechanism: rising temperatures significantly enhance vehicular evaporative nonmethane hydrocarbon (NMHC) emissions. This temperature-dependent increase and subsequent NMHC oxidation to CO2 suggest an overlooked pathway that could amplify climate warming and air pollution globally, particularly after a breakpoint around 2050 (p < 0.05). While historical emissions peaked in the 1990s–2000s, nonexhaust PM becomes increasingly important. Air quality simulations using our inventory in the MUSICA model show good regional PM2.5 agreement but highlight challenges in resolving local primary pollutant peaks. This comprehensive inventory provides crucial data for Brazil and uncovers globally relevant climate–chemistry interactions, urging a re-evaluation of regional specificities in global emission assessments."}],"has_accepted_license":"1","quality_controlled":"1","doi":"10.1021/acs.est.5c08400","publication_identifier":{"eissn":["1520-5851"],"issn":["0013-936X"]},"article_type":"original","ddc":["550"],"oa_version":"None","researchdata_availability":"yes","year":"2026"},{"das_tickbox":"1","intvolume":"        64","OA_type":"hybrid","volume":64,"ec_funded":1,"date_published":"2026-03-01T00:00:00Z","publication":"Reviews of Geophysics","article_processing_charge":"Yes (in subscription journal)","language":[{"iso":"eng"}],"publisher":"Wiley","abstract":[{"text":"Mountain glaciers are among the natural systems most vulnerable to climate change. However, their interactions with the atmosphere are complex and not fully understood. These interactions can trigger rapid adjustments and climate feedbacks that either amplify or attenuate atmospheric signals, influencing both glacier response and large-scale atmospheric circulation. Observing this functional coupling in nature is challenging because the key processes occur over a wide range of spatial and temporal scales. However, recent advances in observational techniques and modeling have provided new insights into these interactions. In this review, we summarize the current state of knowledge on glacier-atmosphere interactions in high-mountain regions at different scales, and highlight recent advances in observational and numerical modeling. We also highlight important knowledge gaps and outline future research directions to improve the prediction of glacier change in a warming world.","lang":"eng"}],"has_accepted_license":"1","doi":"10.1029/2024RG000869","quality_controlled":"1","publication_identifier":{"issn":["8755-1209"],"eissn":["1944-9208"]},"article_type":"original","ddc":["550"],"oa_version":"Published Version","year":"2026","researchdata_availability":"no","_id":"20971","file_date_updated":"2026-07-28T06:48:08Z","scopus_import":"1","article_number":"e2024RG000869","day":"01","dataavailabilitystatement":"Data were not used, nor created for this research. Software (other than for typesetting) was not used for this research.","acknowledgement":"This work is the result of collaboration and discussions within HEFEX II, and we are grateful to all colleagues who have contributed to and enriched these discussions in various ways. T. Sauter acknowledges funding from the German Research Foundation (DFG) (Grant 543257843). This research was funded in part by the Austrian Science Fund (FWF) (Grant https://doi.org/10.55776/P36624 and https://doi.org/10.55776/P36306) for which E. Collier and R. Prinz are grateful. A. R. Groos, T. E. Shaw, R. Mott and M. Haugeneder acknowledge Transnational Access from the European Union's H2020 project INTERACT III (Grant 871120) for participation in the HEFEX II campaign and working group. I. Stiperski (Grant Agreement No. 101001691) and A. R. Groos (Grant Agreement No. 948290) acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program. R. Mott acknowledges funding from the Swiss National Science Foundation (SNSF) (Grant 200021_219918). B. Goger is supported by EXCLAIM, a project funded by ETH Zurich. J.E. Sicart acknowledges LabEx OSUG@2020 (Investissements d'avenir - ANR10 LABX56) for participation in the HEFEX II campaign and working group. T. E. Shaw acknowledges funding from the EU Horizon 2020 Marie Skłodowska-Curie Grant 101026058 and 101034413. K. F. Haualand and T. Sauter are supported by the JOSTICE project funded by the Research Council of Norway (RCN Grant 302458).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"1","OA_place":"publisher","title":"Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review","supplementarymaterial":"no","date_updated":"2026-07-28T06:49:58Z","PlanS_conform":"1","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"}],"citation":{"ieee":"T. Sauter <i>et al.</i>, “Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review,” <i>Reviews of Geophysics</i>, vol. 64, no. 1. Wiley, 2026.","mla":"Sauter, T., et al. “Glacier-Atmosphere Interactions and Feedbacks in High-Mountain Regions - A Review.” <i>Reviews of Geophysics</i>, vol. 64, no. 1, e2024RG000869, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2024RG000869\">10.1029/2024RG000869</a>.","ista":"Sauter T, Brock BW, Collier E, Goger B, Groos AR, Haualand KF, Mott R, Nicholson L, Prinz R, Shaw T, Stiperski I, Georgi A, Haugeneder M, Mandal A, Reynolds D, Saigger M, Sicart JE, Voordendag A. 2026. Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. Reviews of Geophysics. 64(1), e2024RG000869.","short":"T. Sauter, B.W. Brock, E. Collier, B. Goger, A.R. Groos, K.F. Haualand, R. Mott, L. Nicholson, R. Prinz, T. Shaw, I. Stiperski, A. Georgi, M. Haugeneder, A. Mandal, D. Reynolds, M. Saigger, J.E. Sicart, A. Voordendag, Reviews of Geophysics 64 (2026).","ama":"Sauter T, Brock BW, Collier E, et al. Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. <i>Reviews of Geophysics</i>. 2026;64(1). doi:<a href=\"https://doi.org/10.1029/2024RG000869\">10.1029/2024RG000869</a>","chicago":"Sauter, T., B. W. Brock, E. Collier, B. Goger, A. R. Groos, K. F. Haualand, R. Mott, et al. “Glacier-Atmosphere Interactions and Feedbacks in High-Mountain Regions - A Review.” <i>Reviews of Geophysics</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2024RG000869\">https://doi.org/10.1029/2024RG000869</a>.","apa":"Sauter, T., Brock, B. W., Collier, E., Goger, B., Groos, A. R., Haualand, K. F., … Voordendag, A. (2026). Glacier-atmosphere interactions and feedbacks in high-mountain regions - A review. <i>Reviews of Geophysics</i>. Wiley. <a href=\"https://doi.org/10.1029/2024RG000869\">https://doi.org/10.1029/2024RG000869</a>"},"oa":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","type":"journal_article","month":"03","file":[{"relation":"main_file","access_level":"open_access","date_created":"2026-07-28T06:48:08Z","date_updated":"2026-07-28T06:48:08Z","file_name":"2026_ReviewsGeophysics_Sauter.pdf","creator":"dernst","checksum":"9d46167619be91210c45ee9e1f187395","file_id":"22594","success":1,"content_type":"application/pdf","file_size":3012737}],"author":[{"last_name":"Sauter","first_name":"T.","full_name":"Sauter, T."},{"full_name":"Brock, B. W.","last_name":"Brock","first_name":"B. W."},{"full_name":"Collier, E.","first_name":"E.","last_name":"Collier"},{"full_name":"Goger, B.","last_name":"Goger","first_name":"B."},{"full_name":"Groos, A. R.","last_name":"Groos","first_name":"A. R."},{"last_name":"Haualand","first_name":"K. F.","full_name":"Haualand, K. F."},{"full_name":"Mott, R.","first_name":"R.","last_name":"Mott"},{"last_name":"Nicholson","first_name":"L.","full_name":"Nicholson, L."},{"last_name":"Prinz","first_name":"R.","full_name":"Prinz, R."},{"orcid":"0000-0001-7640-6152","first_name":"Thomas","last_name":"Shaw","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","full_name":"Shaw, Thomas"},{"full_name":"Stiperski, I.","last_name":"Stiperski","first_name":"I."},{"full_name":"Georgi, A.","first_name":"A.","last_name":"Georgi"},{"full_name":"Haugeneder, M.","first_name":"M.","last_name":"Haugeneder"},{"last_name":"Mandal","first_name":"A.","full_name":"Mandal, A."},{"full_name":"Reynolds, D.","last_name":"Reynolds","first_name":"D."},{"first_name":"M.","last_name":"Saigger","full_name":"Saigger, M."},{"full_name":"Sicart, J. E.","last_name":"Sicart","first_name":"J. E."},{"full_name":"Voordendag, A.","first_name":"A.","last_name":"Voordendag"}],"publication_status":"published","date_created":"2026-01-11T23:01:33Z","department":[{"_id":"FrPe"}]},{"date_updated":"2026-07-28T06:59:15Z","citation":{"short":"L.M. Becker, P. Schanda, C. Chipot, (2026).","ista":"Becker LM, Schanda P, Chipot C. 2026. Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21145\">10.15479/AT-ISTA-21145</a>.","mla":"Becker, Lea Marie, et al. <i>Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21145\">10.15479/AT-ISTA-21145</a>.","ieee":"L. M. Becker, P. Schanda, and C. Chipot, “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026.","apa":"Becker, L. M., Schanda, P., &#38; Chipot, C. (2026). Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21145\">https://doi.org/10.15479/AT-ISTA-21145</a>","ama":"Becker LM, Schanda P, Chipot C. Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21145\">10.15479/AT-ISTA-21145</a>","chicago":"Becker, Lea Marie, Paul Schanda, and Christophe Chipot. “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21145\">https://doi.org/10.15479/AT-ISTA-21145</a>."},"oa":1,"project":[{"_id":"7be609c4-9f16-11ee-852c-85015ce2b9b0","grant_number":"26777","name":"Exploring protein dynamics by solid-state MAS NMR through specific labeling approaches"}],"title":"Additional Data for \"Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes\"","corr_author":"1","acknowledgement":"We thank Nikolai R. Skrynnikov and Olga O. Lebedenko (St. Petersburg) for insightful discussions and for performing exploratory MD simulations. We are grateful to Tobias Schubeis (Lyon) for advice with GB1 crystallization, and Rebecca Schmid for initial crystallization trials.\r\nWe thank Sebastian Falkner for assistance with constructing the structural model of the IgG:GB1 complex.\r\nThis research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra Rovó and Margarita Valhondo Falcón for excellent support of the NMR facility.\r\nLea M. Becker is recipient of a DOC fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (grant no. PR10660EAW01). Christophe Chipot acknowledges the European Research Council (grant project 101097272 ``MilliInMicro'') and the Métropole du Grand Nancy (grant project ``ARC''). BM07-FIP2 is supported by the French ANR PIA3 (France 2030) EquipEx+ project MAGNIFIX under grant agreement ANR-21-ESRE-0011.","day":"09","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"21145","license":"https://creativecommons.org/licenses/by-nc/4.0/","file_date_updated":"2026-02-05T13:52:41Z","date_created":"2026-02-05T13:54:39Z","department":[{"_id":"GradSch"},{"_id":"PaSc"}],"author":[{"last_name":"Becker","first_name":"Lea Marie","orcid":"0000-0002-6401-5151","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","full_name":"Becker, Lea Marie"},{"full_name":"Schanda, Paul","first_name":"Paul","orcid":"0000-0002-9350-7606","last_name":"Schanda","id":"7B541462-FAF6-11E9-A490-E8DFE5697425"},{"full_name":"Chipot, Christophe","last_name":"Chipot","first_name":"Christophe"}],"related_material":{"record":[{"id":"20641","status":"public","relation":"earlier_version"},{"id":"22105","status":"public","relation":"used_in_publication"}]},"file":[{"file_size":4263,"content_type":"text/plain","file_id":"21146","checksum":"02a419cce8cea450bc952f35488d2df5","creator":"lbecker","file_name":"README.txt","date_updated":"2026-02-05T13:52:37Z","date_created":"2026-02-05T13:52:37Z","access_level":"open_access","relation":"table_of_contents"},{"file_name":"Research_Data.zip","date_created":"2026-02-05T13:52:41Z","date_updated":"2026-02-05T13:52:41Z","access_level":"open_access","relation":"main_file","file_size":50647107,"content_type":"application/zip","success":1,"checksum":"b0b82b1aa73985b0b308a3fa52d21aea","file_id":"21147","creator":"lbecker"}],"type":"research_data","month":"02","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"publisher":"Institute of Science and Technology Austria","contributor":[{"first_name":"Haohao","last_name":"Fu","contributor_type":"researcher"},{"last_name":"Tatman","first_name":"Benjamin","id":"71cda2f3-e604-11ee-a1df-da10587eda3f","contributor_type":"researcher"},{"contributor_type":"researcher","first_name":"Matthias","last_name":"Dreydoppel"},{"first_name":"Anna","last_name":"Kapitonova","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471","contributor_type":"researcher"},{"orcid":"0000-0001-7597-043X","first_name":"Daniel","last_name":"Balazs","contributor_type":"researcher","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E"},{"contributor_type":"researcher","first_name":"Ulrich","last_name":"Weininger"},{"last_name":"Engilberge","first_name":"Sylvain","contributor_type":"researcher"}],"abstract":[{"lang":"eng","text":"Protein conformational energy landscapes are shaped not only by intramolecular interactions but also by their environment. In protein crystals and protein-protein complexes, intermolecular contacts alter this energy landscape, but the exact nature of this alteration is difficult to decipher. Understanding how the crystal lattice affects protein dynamics is crucial for crystallography-based studies of motion, yet its influence on collective motions remains unclear. Aromatic ring flips in the hydrophobic core represent sensitive probes of such dynamics. Here, we compare the kinetics of aromatic ring flips in the protein GB1 in crystals, in complex with its binding partner IgG, and in solution, combining advanced isotope labeling with quantitative NMR methods. We show that rings in the core flip nearly a thousand times less frequently in crystals than in solution. Enhanced-sampling molecular dynamics simulations, based on a new crystal structure, reproduce these elevated barriers and reveal how the crystal restrains motions. "}],"article_processing_charge":"No","date_published":"2026-02-09T00:00:00Z","year":"2026","ddc":["572"],"oa_version":"Published Version","has_accepted_license":"1","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"doi":"10.15479/AT-ISTA-21145"}]