[{"publisher":"AAAS","date_created":"2026-04-26T22:01:46Z","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"},{"name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","grant_number":"101076260","_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb"}],"article_type":"original","_id":"21762","publication":"Science","intvolume":"       392","scopus_import":"1","pmid":1,"quality_controlled":"1","volume":392,"OA_type":"closed access","title":"Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape","author":[{"id":"b4eb62ef-ac72-11ed-9503-ed3b4d66c083","first_name":"Benjamin L","last_name":"Springstein","orcid":"0000-0002-3461-5391","full_name":"Springstein, Benjamin L"},{"id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2","last_name":"Javoor","first_name":"Manjunath","orcid":"0000-0003-2311-2112","full_name":"Javoor, Manjunath"},{"full_name":"Megrian, Daniela","first_name":"Daniela","last_name":"Megrian"},{"id":"ffab949d-133f-11ed-8f02-94de21ace503","last_name":"Hajdu","first_name":"Roman","full_name":"Hajdu, Roman"},{"full_name":"Hanke, Dustin M.","last_name":"Hanke","first_name":"Dustin M."},{"first_name":"Bettina","last_name":"Zens","id":"45FD126C-F248-11E8-B48F-1D18A9856A87","full_name":"Zens, Bettina","orcid":"0000-0002-9561-1239"},{"full_name":"Weiss, Gregor L.","first_name":"Gregor L.","last_name":"Weiss"},{"full_name":"Schur, Florian Km","orcid":"0000-0003-4790-8078","last_name":"Schur","first_name":"Florian Km","id":"48AD8942-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Martin","last_name":"Loose","id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin","orcid":"0000-0001-7309-9724"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"EM-Fac"},{"_id":"LifeSc"}],"language":[{"iso":"eng"}],"related_material":{"record":[{"id":"22744","relation":"dissertation_contains","status":"public"}]},"corr_author":"1","date_published":"2026-04-16T00:00:00Z","month":"04","citation":{"short":"B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L. Weiss, F.K. Schur, M. Loose, Science 392 (2026).","mla":"Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392, no. 6795, eaea6343, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>.","chicago":"Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu, Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>.","ama":"Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795). doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>","ista":"Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL, Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. Science. 392(6795), eaea6343.","apa":"Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens, B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>","ieee":"B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392, no. 6795. AAAS, 2026."},"type":"journal_article","day":"16","ec_funded":1,"issue":"6795","abstract":[{"text":"Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal system named CorMR with a function in cell shape control rather than DNA segregation. Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed that CorM formed dynamically unstable, antiparallel double-stranded filaments that were recruited to the membrane by CorR through an amphipathic helix conserved in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which excluded them from the poles and division plane. Comparative genomics indicated that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity, highlighting the evolutionary plasticity of cytoskeletal systems in bacteria.","lang":"eng"}],"acknowledgement":"We thank all members of the Loose lab at ISTA for helpful discussions; M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University) for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work was funded by the European Union’s Horizon 2020 research and innovation program (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques et Letitia Lopez-Loreta Foundation (G.L.W.).","status":"public","year":"2026","doi":"10.1126/science.aea6343","publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"publication_status":"published","department":[{"_id":"MaLo"},{"_id":"FlSc"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"fulldoi":"https://doi.org/10.1126/science.aea6343","external_id":{"pmid":["41990175"]},"date_updated":"2026-09-03T09:36:24Z","article_number":"eaea6343","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","article_processing_charge":"No"},{"fulldoi":"https://doi.org/10.1038/s41586-026-10846-4","external_id":{"pmid":["42587117"]},"publication_status":"published","researchdata_availability":"yes","department":[{"_id":"JoMa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","article_processing_charge":"Yes (in subscription journal)","date_updated":"2026-09-07T12:50:34Z","day":"13","type":"journal_article","file_date_updated":"2026-09-07T12:49:32Z","dataavailabilitystatement":"The prism spectra obtained as part of JWST-GO-5224 (MoM) featured in this work are available on Zenodo (https://doi.org/10.5281/zenodo.15059214). All processed images and spectra used in this work are publicly available via the DAWN JWST archive (https://dawn-cph.github.io/dja/). All results presented may be reproduced with the open-access reduced data described above and using the following publicly available software whose use is referenced in the text: msaexp, grizli, astropy, Cloudy, SpectRes, pysersic, COLT and numpyro.","month":"08","supplementarymaterial":"yes","citation":{"ieee":"R. P. Naidu <i>et al.</i>, “A gas-enshrouded and gas-reddened black hole at cosmic dawn,” <i>Nature</i>, vol. 656, no. 8127. Springer Nature, pp. 329–333, 2026.","apa":"Naidu, R. P., Matthee, J. J., Katz, H., De Graaff, A., Oesch, P. A., Smith, A., … Whitaker, K. (2026). A gas-enshrouded and gas-reddened black hole at cosmic dawn. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-026-10846-4\">https://doi.org/10.1038/s41586-026-10846-4</a>","ista":"Naidu RP, Matthee JJ, Katz H, De Graaff A, Oesch PA, Smith A, Greene JE, Brammer G, Weibel A, Hviding R, Chisholm J, Labbé I, Simcoe RA, Witten C, Sun WQ, Atek H, Baggen JFW, Belli S, Bezanson R, Boogaard LA, Bose S, Bouwens RJ, Covelo-Paz A, Dayal P, Fudamoto Y, Furtak LJ, Giovinazzo E, Goulding A, Gronke M, Heintz KE, Hirschmann M, Illingworth G, Inoue AK, Johnson BD, Leja J, Leonova E, Mcconachie I, Maseda MV, Natarajan P, Nelson E, Setton DJ, Shivaei I, Sobral D, Stefanon M, Tacchella S, Toft S, Torralba Torregrosa A, Van Dokkum P, Van Der Wel A, Volonteri M, Walter F, Wang B, Watson D, Whitaker K. 2026. A gas-enshrouded and gas-reddened black hole at cosmic dawn. Nature. 656(8127), 329–333.","ama":"Naidu RP, Matthee JJ, Katz H, et al. A gas-enshrouded and gas-reddened black hole at cosmic dawn. <i>Nature</i>. 2026;656(8127):329-333. doi:<a href=\"https://doi.org/10.1038/s41586-026-10846-4\">10.1038/s41586-026-10846-4</a>","short":"R.P. Naidu, J.J. Matthee, H. Katz, A. De Graaff, P.A. Oesch, A. Smith, J.E. Greene, G. Brammer, A. Weibel, R. Hviding, J. Chisholm, I. Labbé, R.A. Simcoe, C. Witten, W.Q. Sun, H. Atek, J.F.W. Baggen, S. Belli, R. Bezanson, L.A. Boogaard, S. Bose, R.J. Bouwens, A. Covelo-Paz, P. Dayal, Y. Fudamoto, L.J. Furtak, E. Giovinazzo, A. Goulding, M. Gronke, K.E. Heintz, M. Hirschmann, G. Illingworth, A.K. Inoue, B.D. Johnson, J. Leja, E. Leonova, I. Mcconachie, M.V. Maseda, P. Natarajan, E. Nelson, D.J. Setton, I. Shivaei, D. Sobral, M. Stefanon, S. Tacchella, S. Toft, A. Torralba Torregrosa, P. Van Dokkum, A. Van Der Wel, M. Volonteri, F. Walter, B. Wang, D. Watson, K. Whitaker, Nature 656 (2026) 329–333.","chicago":"Naidu, Rohan P., Jorryt J Matthee, Harley Katz, Anna De Graaff, Pascal A. Oesch, Aaron Smith, Jenny E. Greene, et al. “A Gas-Enshrouded and Gas-Reddened Black Hole at Cosmic Dawn.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-026-10846-4\">https://doi.org/10.1038/s41586-026-10846-4</a>.","mla":"Naidu, Rohan P., et al. “A Gas-Enshrouded and Gas-Reddened Black Hole at Cosmic Dawn.” <i>Nature</i>, vol. 656, no. 8127, Springer Nature, 2026, pp. 329–33, doi:<a href=\"https://doi.org/10.1038/s41586-026-10846-4\">10.1038/s41586-026-10846-4</a>."},"status":"public","acknowledgement":"This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs 5224 and 3543. R.P.N. is a NASA Hubble Fellow. D.J.S. is a Brinson Prize Fellow. Some of the data products presented in this study were retrieved from the DJA. DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. We acknowledge funding from JWST programmes GO-3516, GO-5224 and GO-1837. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. Funded by the European Union (ERC AGENTS, 101076224; HEAVYMETAL, 101071865; RED CARDINAL, 101076080). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. This work was also supported by JSPS KAKENHI grant no. 23H00131. The Cosmic Dawn Center is funded by the Danish National Research Foundation under grant DNRF140. P.N. acknowledges support from the Gordon and Betty Moore Foundation and the John Templeton Foundation that fund the Black Hole Initiative (BHI) at Harvard University, where she serves as an external prinicpal investigator. S. Bose acknowledges funding from a UK Research and Innovation (UKRI) Future Leaders Fellowship (grant no. MR/V023381/1).","year":"2026","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"doi":"10.1038/s41586-026-10846-4","issue":"8127","abstract":[{"lang":"eng","text":"The physical processes that led to the formation of billion-solar-mass black holes within the first 700 million years of cosmic time, a period known as cosmic dawn, remain a puzzle1. Several theoretical scenarios have been proposed to seed and rapidly grow black holes2,3,4, but direct observations of these mechanisms remain elusive. Here we present a source 660 million years after the Big Bang that exhibits singular properties: among the largest hydrogen Balmer breaks reported at any redshift, broad multi-peaked Hβ emission, and Balmer line absorption in several transitions. We model this source as an enshrouded black hole in which the Balmer break and absorption features are a result of extremely dense, turbulent gas forming a dust-free envelope around a supermassive black hole5,6. This source may provide evidence of an early black hole embedded in dense gas—a theoretical configuration proposed to rapidly grow black holes by super-Eddington accretion7,8. Radiation from the black hole seems to dominate almost all observed light, leaving limited room for contribution from its host galaxy. If the source merged with its brighter neighbour, it would resemble the recently discovered ‘little red dots’ with perplexing spectral energy distributions9,10,11. The redness of the black hole is due to gas, not dust12,13, and scattering, not kinematics, gives rise to the complex line shapes and luminosities—black hole masses of these sources may therefore be overestimated by orders of magnitude."}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"title":"A gas-enshrouded and gas-reddened black hole at cosmic dawn","author":[{"last_name":"Naidu","first_name":"Rohan P.","full_name":"Naidu, Rohan P."},{"id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J"},{"full_name":"Katz, Harley","last_name":"Katz","first_name":"Harley"},{"full_name":"De Graaff, Anna","first_name":"Anna","last_name":"De Graaff"},{"first_name":"Pascal A.","last_name":"Oesch","full_name":"Oesch, Pascal A."},{"first_name":"Aaron","last_name":"Smith","full_name":"Smith, Aaron"},{"last_name":"Greene","first_name":"Jenny E.","full_name":"Greene, Jenny E."},{"full_name":"Brammer, Gabriel","last_name":"Brammer","first_name":"Gabriel"},{"full_name":"Weibel, Andrea","first_name":"Andrea","last_name":"Weibel"},{"full_name":"Hviding, Raphael","first_name":"Raphael","last_name":"Hviding"},{"full_name":"Chisholm, John","first_name":"John","last_name":"Chisholm"},{"last_name":"Labbé","first_name":"Ivo","full_name":"Labbé, Ivo"},{"last_name":"Simcoe","first_name":"Robert A.","full_name":"Simcoe, Robert A."},{"full_name":"Witten, Callum","first_name":"Callum","last_name":"Witten"},{"full_name":"Sun, Wendy Q.","first_name":"Wendy Q.","last_name":"Sun"},{"first_name":"Hakim","last_name":"Atek","full_name":"Atek, Hakim"},{"last_name":"Baggen","first_name":"Josephine F.W.","full_name":"Baggen, Josephine F.W."},{"full_name":"Belli, Sirio","last_name":"Belli","first_name":"Sirio"},{"first_name":"Rachel","last_name":"Bezanson","full_name":"Bezanson, Rachel"},{"last_name":"Boogaard","first_name":"Leindert A.","full_name":"Boogaard, Leindert A."},{"full_name":"Bose, Sownak","first_name":"Sownak","last_name":"Bose"},{"last_name":"Bouwens","first_name":"Rychard J.","full_name":"Bouwens, Rychard J."},{"last_name":"Covelo-Paz","first_name":"Alba","full_name":"Covelo-Paz, Alba"},{"last_name":"Dayal","first_name":"Pratika","full_name":"Dayal, Pratika"},{"full_name":"Fudamoto, Yoshinobu","first_name":"Yoshinobu","last_name":"Fudamoto"},{"first_name":"Lukas J.","last_name":"Furtak","full_name":"Furtak, Lukas J."},{"full_name":"Giovinazzo, Emma","last_name":"Giovinazzo","first_name":"Emma"},{"full_name":"Goulding, Andy","first_name":"Andy","last_name":"Goulding"},{"full_name":"Gronke, Max","first_name":"Max","last_name":"Gronke"},{"full_name":"Heintz, Kasper E.","last_name":"Heintz","first_name":"Kasper E."},{"full_name":"Hirschmann, Michaela","first_name":"Michaela","last_name":"Hirschmann"},{"first_name":"Garth","last_name":"Illingworth","full_name":"Illingworth, Garth"},{"full_name":"Inoue, Akio K.","last_name":"Inoue","first_name":"Akio K."},{"full_name":"Johnson, Benjamin D.","first_name":"Benjamin D.","last_name":"Johnson"},{"full_name":"Leja, Joel","last_name":"Leja","first_name":"Joel"},{"full_name":"Leonova, Ecaterina","first_name":"Ecaterina","last_name":"Leonova"},{"full_name":"Mcconachie, Ian","first_name":"Ian","last_name":"Mcconachie"},{"first_name":"Michael V.","last_name":"Maseda","full_name":"Maseda, Michael V."},{"full_name":"Natarajan, Priyamvada","first_name":"Priyamvada","last_name":"Natarajan"},{"last_name":"Nelson","first_name":"Erica","full_name":"Nelson, Erica"},{"last_name":"Setton","first_name":"David J.","full_name":"Setton, David J."},{"first_name":"Irene","last_name":"Shivaei","full_name":"Shivaei, Irene"},{"first_name":"David","last_name":"Sobral","full_name":"Sobral, David"},{"full_name":"Stefanon, Mauro","last_name":"Stefanon","first_name":"Mauro"},{"last_name":"Tacchella","first_name":"Sandro","full_name":"Tacchella, Sandro"},{"first_name":"Sune","last_name":"Toft","full_name":"Toft, Sune"},{"full_name":"Torralba Torregrosa, Alberto","orcid":"0000-0001-5586-6950","first_name":"Alberto","last_name":"Torralba Torregrosa","id":"018f0249-0e87-11f0-b167-cbce08fbd541"},{"full_name":"Van Dokkum, Pieter","first_name":"Pieter","last_name":"Van Dokkum"},{"full_name":"Van Der Wel, Arjen","first_name":"Arjen","last_name":"Van Der Wel"},{"full_name":"Volonteri, Marta","last_name":"Volonteri","first_name":"Marta"},{"last_name":"Walter","first_name":"Fabian","full_name":"Walter, Fabian"},{"full_name":"Wang, Bingjie","first_name":"Bingjie","last_name":"Wang"},{"full_name":"Watson, Darach","first_name":"Darach","last_name":"Watson"},{"full_name":"Whitaker, Katherine","first_name":"Katherine","last_name":"Whitaker"}],"pmid":1,"quality_controlled":"1","volume":656,"PlanS_conform":"1","OA_type":"hybrid","OA_place":"publisher","date_published":"2026-08-13T00:00:00Z","file":[{"date_updated":"2026-09-07T12:49:32Z","date_created":"2026-09-07T12:49:32Z","file_name":"2026_Nature_Naidu.pdf","creator":"dernst","content_type":"application/pdf","checksum":"80127691cb39deb39948c337f6915f7b","access_level":"open_access","success":1,"file_size":15134062,"file_id":"22841","relation":"main_file"}],"language":[{"iso":"eng"}],"publisher":"Springer Nature","page":"329-333","das_tickbox":"1","ddc":["520"],"_id":"22751","publication":"Nature","scopus_import":"1","intvolume":"       656","date_created":"2026-08-23T22:01:46Z","oa":1,"has_accepted_license":"1","article_type":"original"},{"publisher":"Springer Nature","DOAJ_listed":"1","publication":"Nature Communications","intvolume":"        17","scopus_import":"1","ddc":["570"],"das_tickbox":"1","_id":"22750","has_accepted_license":"1","article_type":"original","oa":1,"date_created":"2026-08-23T22:01:46Z","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"ScienComp"}],"author":[{"full_name":"Zhao, Ziyu","last_name":"Zhao","first_name":"Ziyu","id":"a63fe682-9f3a-11ee-bf8c-cfdf919b9850"},{"last_name":"Vercellino","first_name":"Irene","id":"3ED6AF16-F248-11E8-B48F-1D18A9856A87","full_name":"Vercellino, Irene","orcid":"0000-0001-5618-3449"},{"full_name":"Whitelegge, Julian P.","last_name":"Whitelegge","first_name":"Julian P."},{"full_name":"Maghlaoui, Karim","last_name":"Maghlaoui","first_name":"Karim"},{"first_name":"Wojciech","last_name":"Białek","full_name":"Białek, Wojciech"},{"first_name":"Peter J.","last_name":"Nixon","full_name":"Nixon, Peter J."},{"orcid":"0000-0002-0977-7989","full_name":"Sazanov, Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A","last_name":"Sazanov"}],"title":"Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster","OA_place":"publisher","quality_controlled":"1","pmid":1,"OA_type":"gold","volume":17,"corr_author":"1","date_published":"2026-08-17T00:00:00Z","file":[{"checksum":"a820b736585de22bcfa30ebdd25a6dd2","access_level":"open_access","success":1,"file_size":3370665,"file_id":"22843","relation":"main_file","date_updated":"2026-09-07T13:13:03Z","date_created":"2026-09-07T13:13:03Z","creator":"dernst","file_name":"2026_NatureComm_Zhao.pdf","content_type":"application/pdf"}],"language":[{"iso":"eng"}],"dataavailabilitystatement":"The cryo-EM maps are deposited in the Electron Microscopy Data Bank under accession number EMD- 51100 (inactive dimer), EMD- 51102 (active dimer) and EMD-51101 (semi-active dimer). The models are deposited in the Protein Data Bank under accession numbers 9G6F (inactive dimer), 9G6H (active dimer) and 9G6G (semi-active dimer). Mass spectrometry data was uploaded to MassIVE with accession code MSV000101057. Source data are provided with this paper.","day":"17","type":"journal_article","file_date_updated":"2026-09-07T13:13:03Z","citation":{"apa":"Zhao, Z., Vercellino, I., Whitelegge, J. P., Maghlaoui, K., Białek, W., Nixon, P. J., &#38; Sazanov, L. A. (2026). Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-75324-x\">https://doi.org/10.1038/s41467-026-75324-x</a>","ieee":"Z. Zhao <i>et al.</i>, “Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ama":"Zhao Z, Vercellino I, Whitelegge JP, et al. Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-75324-x\">10.1038/s41467-026-75324-x</a>","ista":"Zhao Z, Vercellino I, Whitelegge JP, Maghlaoui K, Białek W, Nixon PJ, Sazanov LA. 2026. Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster. Nature Communications. 17, 8433.","short":"Z. Zhao, I. Vercellino, J.P. Whitelegge, K. Maghlaoui, W. Białek, P.J. Nixon, L.A. Sazanov, Nature Communications 17 (2026).","chicago":"Zhao, Ziyu, Irene Vercellino, Julian P. Whitelegge, Karim Maghlaoui, Wojciech Białek, Peter J. Nixon, and Leonid A Sazanov. “Cryo-EM Structures of Naturally Occurring Dimeric Photosystem II Complexes Lacking the Mn4CaO5 Cluster.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-75324-x\">https://doi.org/10.1038/s41467-026-75324-x</a>.","mla":"Zhao, Ziyu, et al. “Cryo-EM Structures of Naturally Occurring Dimeric Photosystem II Complexes Lacking the Mn4CaO5 Cluster.” <i>Nature Communications</i>, vol. 17, 8433, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-75324-x\">10.1038/s41467-026-75324-x</a>."},"month":"08","supplementarymaterial":"yes","doi":"10.1038/s41467-026-75324-x","publication_identifier":{"eissn":["2041-1723"]},"status":"public","acknowledgement":"P.J.N. is grateful for the support from the Imperial College Electron Microscopy Center. L.A.S. acknowledges the support from the Scientific Service Units (SSU) of IST Austria: the Electron Microscopy Facility (EMF), the Life Science Facility (LSF) and the IST high-performance computing cluster. P.J.N. is grateful for the support of the Biotechnology & Biological Sciences Research Council (awards BB/I00937X/1, BB/L003260/1 and BB/P00931X/1). L.A.S. is grateful to IST Austria for providing the funding.","year":"2026","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"abstract":[{"text":"Robust oxygenic photosynthesis requires the efficient assembly and repair of the multi-subunit oxygen-evolving photosystem II (PSII) complex. Previous cryogenic electron microscopy (cryo-EM) structures of PSII assembly/disassembly intermediates have relied on the analysis of deletion mutants or removal of PSII subunits in vitro. Here we report the cryo-EM structures of naturally occurring dimeric PSII intermediates from the cyanobacterium Thermosynechococcus vestitus at a resolution of about 2.2 Å. These intermediates contain inactive dimers lacking the oxygen-evolving complex (OEC) and semi-active dimers with the OEC present in one of the two monomers. Our structural data provide a mechanism for how assembly and disassembly of the Mn4CaO5 cluster is coordinated with the binding and release of the extrinsic proteins: restructuring of the C-terminal tail of D1 subunit during assembly or disassembly of the Mn cluster triggers conformational changes in D2, CP47 and CP43 to drive the binding/release of the extrinsic proteins. A combination of structural and mass spectrometry data also suggests that the inactive PSII complexes may include damaged complexes containing oxidized D1-His332, a monodentate ligand to one of the Mn ions of the OEC.","lang":"eng"}],"external_id":{"pmid":["42420307"]},"fulldoi":"https://doi.org/10.1038/s41467-026-75324-x","department":[{"_id":"LeSa"}],"publication_status":"published","researchdata_availability":"yes","article_processing_charge":"Yes","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-09-07T13:17:53Z","article_number":"8433"},{"file_date_updated":"2026-09-07T13:53:26Z","type":"journal_article","day":"01","citation":{"ama":"Anastos M, Erde J, Kang M, Pfenninger V. A short proof of a central limit theorem for the order of the giant component and k-core. <i>Bulletin of the London Mathematical Society</i>. 2026;58(8). doi:<a href=\"https://doi.org/10.1112/blms.70464\">10.1112/blms.70464</a>","ieee":"M. Anastos, J. Erde, M. Kang, and V. Pfenninger, “A short proof of a central limit theorem for the order of the giant component and k-core,” <i>Bulletin of the London Mathematical Society</i>, vol. 58, no. 8. Wiley, 2026.","ista":"Anastos M, Erde J, Kang M, Pfenninger V. 2026. A short proof of a central limit theorem for the order of the giant component and k-core. Bulletin of the London Mathematical Society. 58(8), e70464.","apa":"Anastos, M., Erde, J., Kang, M., &#38; Pfenninger, V. (2026). A short proof of a central limit theorem for the order of the giant component and k-core. <i>Bulletin of the London Mathematical Society</i>. Wiley. <a href=\"https://doi.org/10.1112/blms.70464\">https://doi.org/10.1112/blms.70464</a>","chicago":"Anastos, Michael, Joshua Erde, Mihyun Kang, and Vincent Pfenninger. “A Short Proof of a Central Limit Theorem for the Order of the Giant Component and K-Core.” <i>Bulletin of the London Mathematical Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1112/blms.70464\">https://doi.org/10.1112/blms.70464</a>.","mla":"Anastos, Michael, et al. “A Short Proof of a Central Limit Theorem for the Order of the Giant Component and K-Core.” <i>Bulletin of the London Mathematical Society</i>, vol. 58, no. 8, e70464, Wiley, 2026, doi:<a href=\"https://doi.org/10.1112/blms.70464\">10.1112/blms.70464</a>.","short":"M. Anastos, J. Erde, M. Kang, V. Pfenninger, Bulletin of the London Mathematical Society 58 (2026)."},"supplementarymaterial":"no","month":"08","publication_identifier":{"eissn":["1469-2120"],"issn":["0024-6093"]},"doi":"10.1112/blms.70464","year":"2026","acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/P36131 (Joshua Erde), 10.55776/I6502 (Mihyun Kang), 10.55776/ESP3863424 (Michael Anastos)] and by the Swiss National Science Foundation (SNSF) [P500-2_235474] (Vincent Pfenninger). For open access purposes, the authors have applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. The authors thank the reviewers for helpful comments on the paper, and for bringing the particular form of Theorem 2.2 to our attention.","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"In this note we outline a new and simple approach to proving central limit theorems for various ‘global’ graph parameters that have robust ‘local’ approximations, using the Efron–Stein inequality, which relies on a combinatorial analysis of the stability of these approximations under resampling an edge. As an application, we give short proofs of a central limit theorem for the order of the giant component and of the 𝑘\r\n-core for sparse random graphs."}],"issue":"8","external_id":{"arxiv":["2506.11651"]},"fulldoi":"https://doi.org/10.1112/blms.70464","department":[{"_id":"MaKw"}],"researchdata_availability":"no","publication_status":"published","article_processing_charge":"Yes (in subscription journal)","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e70464","date_updated":"2026-09-07T13:56:17Z","publisher":"Wiley","intvolume":"        58","scopus_import":"1","publication":"Bulletin of the London Mathematical Society","_id":"22752","das_tickbox":"0","ddc":["510"],"article_type":"original","project":[{"name":"Combinatorial Optimisation Problems on Sparse Random Graphs","_id":"8f906bd2-16d5-11f0-9cad-e07be8aa9ac9","grant_number":"ESP3863424"}],"has_accepted_license":"1","oa":1,"date_created":"2026-08-23T22:01:47Z","author":[{"full_name":"Anastos, Michael","id":"0b2a4358-bb35-11ec-b7b9-e3279b593dbb","last_name":"Anastos","first_name":"Michael"},{"first_name":"Joshua","last_name":"Erde","full_name":"Erde, Joshua"},{"full_name":"Kang, Mihyun","first_name":"Mihyun","last_name":"Kang"},{"last_name":"Pfenninger","first_name":"Vincent","full_name":"Pfenninger, Vincent"}],"title":"A short proof of a central limit theorem for the order of the giant component and k-core","OA_place":"publisher","PlanS_conform":"1","OA_type":"hybrid","volume":58,"quality_controlled":"1","mathsc":["05C80","60F05"],"file":[{"access_level":"open_access","checksum":"b4b21f05c3fc62fde243a5ddd46cef49","relation":"main_file","file_id":"22845","file_size":248641,"success":1,"date_updated":"2026-09-07T13:53:26Z","date_created":"2026-09-07T13:53:26Z","content_type":"application/pdf","creator":"dernst","file_name":"2026_BulletinLondonMathSoc_Anastos.pdf"}],"date_published":"2026-08-01T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}]},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Quantitative automata (QAs) extend finite-state automata on infinite words with weighted transitions to specify quantitative system properties. However, their finite weight sets rule out properties like average response time, where response times can be arbitrarily large. Nested quantitative automata (NQAs) overcome this limitation: a parent automaton spawns child automata to compute unbounded values over finite infixes and aggregates them into a final result. Despite this expressiveness, NQAs have lacked practical tool support to date.\r\n\r\nWe close this gap by extending the Quantitative Automata Kit (QuAK), a software tool for QA analysis, to support NQAs. Our core contribution is implementing a suite of flattening procedures that reduce NQAs to QAs, leveraging QuAK’s existing decision procedures. These reductions preserve the answers to threshold decision problems, while allowing users to specify properties in the more expressive NQA formalism. The tool handles all combinations of parent aggregators (including limits and averages) and child functions (extrema and monotonic or bounded summations) for which emptiness and universality are known to be decidable. Experiments on response-time and resource-consumption benchmarks demonstrate QuAK’s effectiveness."}],"publication_identifier":{"isbn":["9783032325259"],"issn":["0302-9743"],"eissn":["1611-3349"]},"doi":"10.1007/978-3-032-32526-6_20","year":"2026","status":"public","acknowledgement":"This work was supported by the European Research Council (ERC) Grants VAMOS (No. 101020093) and HYPER (No. 101055412).","citation":{"ieee":"T. A. Henzinger, N. A. Mazzocchi, N. E. Sarac, and H. Yılmaz, “Extending QuAK with nested quantitative automata,” in <i>38th International Conference on Computer Aided Verification</i>, Lisbon, Portugal, 2026, vol. 16683, pp. 418–432.","apa":"Henzinger, T. A., Mazzocchi, N. A., Sarac, N. E., &#38; Yılmaz, H. (2026). Extending QuAK with nested quantitative automata. In <i>38th International Conference on Computer Aided Verification</i> (Vol. 16683, pp. 418–432). Lisbon, Portugal: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-32526-6_20\">https://doi.org/10.1007/978-3-032-32526-6_20</a>","ama":"Henzinger TA, Mazzocchi NA, Sarac NE, Yılmaz H. Extending QuAK with nested quantitative automata. In: <i>38th International Conference on Computer Aided Verification</i>. Vol 16683. Springer Nature; 2026:418-432. doi:<a href=\"https://doi.org/10.1007/978-3-032-32526-6_20\">10.1007/978-3-032-32526-6_20</a>","ista":"Henzinger TA, Mazzocchi NA, Sarac NE, Yılmaz H. 2026. Extending QuAK with nested quantitative automata. 38th International Conference on Computer Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 16683, 418–432.","short":"T.A. Henzinger, N.A. Mazzocchi, N.E. Sarac, H. Yılmaz, in:, 38th International Conference on Computer Aided Verification, Springer Nature, 2026, pp. 418–432.","mla":"Henzinger, Thomas A., et al. “Extending QuAK with Nested Quantitative Automata.” <i>38th International Conference on Computer Aided Verification</i>, vol. 16683, Springer Nature, 2026, pp. 418–32, doi:<a href=\"https://doi.org/10.1007/978-3-032-32526-6_20\">10.1007/978-3-032-32526-6_20</a>.","chicago":"Henzinger, Thomas A, Nicolas Adrien Mazzocchi, Naci E Sarac, and Harun Yılmaz. “Extending QuAK with Nested Quantitative Automata.” In <i>38th International Conference on Computer Aided Verification</i>, 16683:418–32. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-32526-6_20\">https://doi.org/10.1007/978-3-032-32526-6_20</a>."},"month":"01","supplementarymaterial":"no","ec_funded":1,"dataavailabilitystatement":"The artifact supporting the experimental results in this paper is available in the QuAK repository at https://github.com/ista-vamos/nested-quak. It contains the extended QuAK implementation, benchmark generators, example inputs, and scripts/logs for reproducing the reported tables. The artifact is intended to reproduce the experiments under the setup described in Sect. 4; runtimes may vary across machines, and the reported timeout and memory-exhaustion results depend on the stated hardware limits. No sensitive or restricted data are used. An archived version is available on Zenodo at DOI: http://doi.org/10.5281/zenodo.19844606.","file_date_updated":"2026-09-09T06:33:55Z","type":"conference","day":"01","date_updated":"2026-09-09T06:37:41Z","article_processing_charge":"No","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"ToHe"}],"researchdata_availability":"yes","publication_status":"published","external_id":{"arxiv":["2605.12418"]},"fulldoi":"https://doi.org/10.1007/978-3-032-32526-6_20","project":[{"grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020"}],"has_accepted_license":"1","date_created":"2026-08-23T22:01:47Z","oa":1,"intvolume":"     16683","scopus_import":"1","publication":"38th International Conference on Computer Aided Verification","_id":"22754","das_tickbox":"1","ddc":["000"],"page":"418-432","alternative_title":["LNCS"],"conference":{"end_date":"2026-07-29","location":"Lisbon, Portugal","start_date":"2026-07-26","name":"CAV: Computer Aided Verification"},"publisher":"Springer Nature","arxiv":1,"language":[{"iso":"eng"}],"file":[{"access_level":"open_access","checksum":"043ba7b83f28d036d5a0e6e70a52cc9a","file_id":"22861","relation":"main_file","file_size":425988,"success":1,"date_created":"2026-09-09T06:33:55Z","date_updated":"2026-09-09T06:33:55Z","content_type":"application/pdf","file_name":"2026_LNCS_HenzingerT.pdf","creator":"dernst"}],"date_published":"2026-01-01T00:00:00Z","OA_place":"publisher","volume":16683,"OA_type":"hybrid","quality_controlled":"1","title":"Extending QuAK with nested quantitative automata","author":[{"first_name":"Thomas A","last_name":"Henzinger","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","full_name":"Henzinger, Thomas A","orcid":"0000-0002-2985-7724"},{"last_name":"Mazzocchi","first_name":"Nicolas Adrien","id":"b26baa86-3308-11ec-87b0-8990f34baa85","full_name":"Mazzocchi, Nicolas Adrien"},{"first_name":"Naci E","last_name":"Sarac","id":"8C6B42F8-C8E6-11E9-A03A-F2DCE5697425","full_name":"Sarac, Naci E"},{"first_name":"Harun","last_name":"Yılmaz","full_name":"Yılmaz, Harun"}]},{"dataavailabilitystatement":"There are no publicly available research data or software supporting this manuscript. Requests for further information or data should be sent to the authors.","file_date_updated":"2026-09-09T07:00:24Z","type":"journal_article","day":"18","citation":{"ieee":"M. Serbyn, A. Avdoshkin, O. K. Diessel, and D. A. Huse, “Eigenstate thermalization in thermal first-order phase transitions,” <i>Physical Review X</i>, vol. 16, no. 3. American Physical Society, 2026.","ama":"Serbyn M, Avdoshkin A, Diessel OK, Huse DA. Eigenstate thermalization in thermal first-order phase transitions. <i>Physical Review X</i>. 2026;16(3). doi:<a href=\"https://doi.org/10.1103/4zs8-7kf4\">10.1103/4zs8-7kf4</a>","ista":"Serbyn M, Avdoshkin A, Diessel OK, Huse DA. 2026. Eigenstate thermalization in thermal first-order phase transitions. Physical Review X. 16(3), 031042.","apa":"Serbyn, M., Avdoshkin, A., Diessel, O. K., &#38; Huse, D. A. (2026). Eigenstate thermalization in thermal first-order phase transitions. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/4zs8-7kf4\">https://doi.org/10.1103/4zs8-7kf4</a>","short":"M. Serbyn, A. Avdoshkin, O.K. Diessel, D.A. Huse, Physical Review X 16 (2026).","chicago":"Serbyn, Maksym, Alexander Avdoshkin, Oriana K. Diessel, and David A. Huse. “Eigenstate Thermalization in Thermal First-Order Phase Transitions.” <i>Physical Review X</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/4zs8-7kf4\">https://doi.org/10.1103/4zs8-7kf4</a>.","mla":"Serbyn, Maksym, et al. “Eigenstate Thermalization in Thermal First-Order Phase Transitions.” <i>Physical Review X</i>, vol. 16, no. 3, 031042, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/4zs8-7kf4\">10.1103/4zs8-7kf4</a>."},"supplementarymaterial":"yes","month":"08","doi":"10.1103/4zs8-7kf4","publication_identifier":{"issn":["2160-3308"]},"year":"2026","status":"public","acknowledgement":"A. A. acknowledges discussions and prior collaboration on related topics with Anatoly Dymarsky. M. S. acknowledges Ashwin Vishwanath for introducing him to the idea of thermal first-order phase transitions in quantum systems. This research was supported in part by Grant No. NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP) and by the Erwin Schrödinger International Institute for Mathematics and Physics (ESI). O. K. D. acknowledges support from the NSF through a grant for ITAMP at Harvard University. D. A. H. was supported in part by NSF QLCI Grant No. OMA-2120757.","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"The eigenstate thermalization hypothesis (ETH) posits how isolated quantum many-body systems thermalize, assuming that individual eigenstates at the same energy density have identical expectation values of local observables in the limit of large systems. While the ETH apparently holds across a wide range of interacting quantum systems, in this work, we show that it may require generalization in the presence of thermal first-order phase transitions. We introduce a class of all-to-all spin models, featuring first-order thermal phase transitions that stem from two distinct local maxima of entropy (two mean-field solutions that we dub “branches”) that exchange dominance in the many-body density of states as the energy is varied. We argue that, for energies in the vicinity of the thermal phase transition, eigenstate expectation values do not need to converge to the same thermal value. The system has a regime with coexistence of two classes of eigenstates corresponding to the two branches with distinct expectation values at the same energy density and another regime with Schrödinger-cat-like eigenstates that are interbranch superpositions; these two regimes are separated by an eigenstate phase transition. We propose a more general form of the ETH , support our results by semiclassical calculations and an exact diagonalization study of a microscopic spin model, and argue that the structure of eigenstates in the vicinity of thermal first-order phase transitions can be experimentally probed via nonequilibrium dynamics."}],"issue":"3","external_id":{"arxiv":["2601.08347"]},"fulldoi":"https://doi.org/10.1103/4zs8-7kf4","department":[{"_id":"MaSe"}],"publication_status":"published","researchdata_availability":"upon request","article_processing_charge":"Yes","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"031042","date_updated":"2026-09-09T07:01:47Z","publisher":"American Physical Society","DOAJ_listed":"1","intvolume":"        16","scopus_import":"1","publication":"Physical Review X","_id":"22755","ddc":["530"],"das_tickbox":"1","article_type":"original","has_accepted_license":"1","oa":1,"date_created":"2026-08-24T06:57:25Z","title":"Eigenstate thermalization in thermal first-order phase transitions","author":[{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","last_name":"Serbyn","first_name":"Maksym","orcid":"0000-0002-2399-5827","full_name":"Serbyn, Maksym"},{"first_name":"Alexander","last_name":"Avdoshkin","full_name":"Avdoshkin, Alexander"},{"first_name":"Oriana K.","last_name":"Diessel","full_name":"Diessel, Oriana K."},{"first_name":"David A.","last_name":"Huse","full_name":"Huse, David A."}],"OA_place":"publisher","OA_type":"gold","volume":16,"PlanS_conform":"1","quality_controlled":"1","file":[{"date_updated":"2026-09-09T07:00:24Z","date_created":"2026-09-09T07:00:24Z","content_type":"application/pdf","creator":"dernst","file_name":"2026_PhysicalReviewX_Serbyn.pdf","checksum":"8bf0d88f17783dc1e6bf4c754534d734","access_level":"open_access","relation":"main_file","file_id":"22862","success":1,"file_size":2537492}],"date_published":"2026-08-18T00:00:00Z","corr_author":"1","arxiv":1,"language":[{"iso":"eng"}]},{"oa":1,"date_created":"2026-08-23T22:01:47Z","article_type":"original","project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression"},{"call_identifier":"H2020","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","_id":"260018B0-B435-11E9-9278-68D0E5697425","grant_number":"725780"}],"has_accepted_license":"1","_id":"22753","ddc":["570"],"das_tickbox":"1","scopus_import":"1","publication":"Nature","publisher":"Springer Nature","language":[{"iso":"eng"}],"file":[{"file_id":"22844","relation":"main_file","file_size":48513068,"success":1,"checksum":"11383e28fc430b28d2666f73833e8b56","access_level":"open_access","content_type":"application/pdf","creator":"dernst","file_name":"2026_Nature_Stouffer.pdf","date_created":"2026-09-07T13:24:10Z","date_updated":"2026-09-07T13:24:10Z"}],"corr_author":"1","date_published":"2026-08-12T00:00:00Z","OA_type":"hybrid","PlanS_conform":"1","pmid":1,"quality_controlled":"1","OA_place":"publisher","title":"Temporal uncoupling of radial glia lineage progression in cortical organoids","author":[{"first_name":"Melissa A","last_name":"Stouffer","id":"4C9372C4-F248-11E8-B48F-1D18A9856A87","full_name":"Stouffer, Melissa A"},{"orcid":"0000-0001-6618-6889","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","first_name":"Osvaldo","last_name":"Miranda"},{"full_name":"Pauler, Florian","orcid":"0000-0002-7462-0048","first_name":"Florian","last_name":"Pauler","id":"48EA0138-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Pipicelli, Fabrizia","last_name":"Pipicelli","first_name":"Fabrizia","id":"649134fd-d012-11ed-8f82-db1e5050f9ba"},{"full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","first_name":"Carmen","last_name":"Streicher"},{"id":"471195F6-F248-11E8-B48F-1D18A9856A87","last_name":"Cheung","first_name":"Giselle T","orcid":"0000-0001-8457-2572","full_name":"Cheung, Giselle T"},{"last_name":"Hippenmeyer","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"abstract":[{"lang":"eng","text":"Radial glial progenitors (RGPs) produce all excitatory neurons in the developing cerebral cortex. Mosaic analysis with double markers (MADM)-based lineage tracing in vivo has revealed a quantitative framework of RGP lineage progression1. Here we established MADM technology2,3 in mouse embryonic stem cells to probe RGP lineage progression in a self-organizing cortical organoid system. We found that RGPs exhibit a high level of plasticity in proliferative potential in organoids rather than strict temporally stereotyped lineage progression as observed in vivo. RGPs in organoids showed increased lineage restriction, diminishing cell-type diversity in clones of cortical projection neurons, despite uniform single-cell transcriptional signatures of RGPs and a unitary lineage trajectory. Thus, critical non-cell-autonomous cues that are absent in self-organizing systems and/or the genuine stem cell niche are essential for faithful temporal control of RGP lineage progression and the generation of clonal cortical cell-type diversity."}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"year":"2026","status":"public","acknowledgement":"We thank M. L. de Guevara, S. Jayaram and A. Heger for technical assistance with mESC derivation; M. Goudarzi for assistance with organoid imaging; M. Leeb and F. Freeman for advice in culturing mESCs and organoids; S. Gobeil and L. Sweeney for reagents and advice for organoid clearing; A. Heger for mouse colony management; J. Hauser for technical assistance; the Stanford Brain Organogenesis Workshop; and all members of the Hippenmeyer laboratory for discussion and/or comments on the manuscript. This study was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology, Austria through resources provided by the Imaging and Optics Facility (IOF), Laboratory Support Facility (LSF) and Preclinical Facility (PCF). M.S. received funding from the European Commission (IST plus postdoctoral fellowship). This work was supported by ISTA institutional funds to S.H., FWF SFB F78 Neuro Stem Modulation to S.H., and by the European Research Council (ERC) under the European Union’s Horizon 2020 Research And Innovation Program (grant agreement 725780 LinPro) to S.H. Open access funding provided by Institute of Science and Technology (IST Austria).","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"doi":"10.1038/s41586-026-10916-7","month":"08","supplementarymaterial":"yes","citation":{"mla":"Stouffer, Melissa A., et al. “Temporal Uncoupling of Radial Glia Lineage Progression in Cortical Organoids.” <i>Nature</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41586-026-10916-7\">10.1038/s41586-026-10916-7</a>.","chicago":"Stouffer, Melissa A, Osvaldo Miranda, Florian Pauler, Fabrizia Pipicelli, Carmen Streicher, Giselle T Cheung, and Simon Hippenmeyer. “Temporal Uncoupling of Radial Glia Lineage Progression in Cortical Organoids.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-026-10916-7\">https://doi.org/10.1038/s41586-026-10916-7</a>.","short":"M.A. Stouffer, O. Miranda, F. Pauler, F. Pipicelli, C. Streicher, G.T. Cheung, S. Hippenmeyer, Nature (2026).","ista":"Stouffer MA, Miranda O, Pauler F, Pipicelli F, Streicher C, Cheung GT, Hippenmeyer S. 2026. Temporal uncoupling of radial glia lineage progression in cortical organoids. Nature.","apa":"Stouffer, M. A., Miranda, O., Pauler, F., Pipicelli, F., Streicher, C., Cheung, G. T., &#38; Hippenmeyer, S. (2026). Temporal uncoupling of radial glia lineage progression in cortical organoids. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-026-10916-7\">https://doi.org/10.1038/s41586-026-10916-7</a>","ieee":"M. A. Stouffer <i>et al.</i>, “Temporal uncoupling of radial glia lineage progression in cortical organoids,” <i>Nature</i>. Springer Nature, 2026.","ama":"Stouffer MA, Miranda O, Pauler F, et al. Temporal uncoupling of radial glia lineage progression in cortical organoids. <i>Nature</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41586-026-10916-7\">10.1038/s41586-026-10916-7</a>"},"file_date_updated":"2026-09-07T13:24:10Z","day":"12","type":"journal_article","dataavailabilitystatement":"All data generated and analysed in this study are included in the paper, source data and/or Supplementary Tables 2 and 3. Raw sequencing data have been deposited with Gene Expression Omnibus (GEO) accession number GSE327470. Source data are provided with this paper. All scripts used to prepare data and figures for this manuscript are accessible on GitHub at https://github.com/fpauler/Temporal-Uncoupling-of-Radial-Glia-Lineage-Progression-in-Cortical-Organoid.","ec_funded":1,"date_updated":"2026-09-09T07:11:02Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","publication_status":"epub_ahead","researchdata_availability":"yes","department":[{"_id":"SiHi"}],"fulldoi":"https://doi.org/10.1038/s41586-026-10916-7","external_id":{"pmid":["42587153"]}},{"article_processing_charge":"Yes","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"8769","date_updated":"2026-09-09T07:28:15Z","external_id":{"pmid":["42469237"],"arxiv":["2507.10530"]},"fulldoi":"https://doi.org/10.1038/s41467-026-75654-w","department":[{"_id":"DaAl"},{"_id":"GradSch"}],"publication_status":"published","researchdata_availability":"yes","publication_identifier":{"eissn":["2041-1723"]},"doi":"10.1038/s41467-026-75654-w","year":"2026","acknowledgement":"P.T. thanks valued discussions with Dr. Peichen Zhong, Dr. Hao Tang, and Dr. Chengbin Zhao. P.T. thanks Dr. Dingshun Lv, Dr. Zechang Sun, and Dr. Chenxi Hu for identifying an important bug in an early version of the code package. The authors acknowledge the resources of the National Energy Research Scientific Computing Center (NERSC), a Department of Energy Office of Science User Facility using NERSC award DOEERCAP0031751 ‘GenAI@NERSC’. P.T. acknowledges funding from the BIDMaP Postdoctoral Fellowship.","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Elucidating reaction mechanisms requires efficient generation of transition states (TSs) and products. Existing diffusion and sequence-based models accelerate parts of this process over traditional string-based methods, but typically still require manual enumeration of either TSs or products, and stochastic diffusion dynamics can be inefficient and hard to control. We introduce MolGEN, a conditional flow-matching framework that uses deterministic optimal transport to map Gaussian priors to chemical distributions. For TS generation, MolGEN improves TS geometry and barrier-height prediction over diffusion models while enabling sub-second sampling. For reaction product generation, it achieves competitive top-k accuracy while preserving mass and electron balance. Using the same backbone for TS and product sampling, MolGEN enables template-free generative exploration of reaction networks without the repeated quantum-chemistry searches required by prior methods. For the γ-ketohydroperoxide decomposition network, it produces more valid TSs than string-based methods using only 12 quantum-chemistry evaluations instead of 1156, and identifies a lower-barrier pathway."}],"dataavailabilitystatement":"Structures generated in this study are provided in the Source Data file, and deposited in the GitHub repository https://github.com/tuoping/MolGEN and the figshare database under accession code https://doi.org/10.6084/m9.figshare.30576365. Source data are provided in this paper. The MolGEN codebase is available as an open-source repository for continuous development at https://github.com/tuoping/MolGEN. A release of the code used in this work has been archived on Zenodo47.","file_date_updated":"2026-09-09T07:25:19Z","type":"journal_article","day":"21","citation":{"ama":"Tuo P, Chen J, Li J. Flow matching for reaction pathway generation. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-75654-w\">10.1038/s41467-026-75654-w</a>","ieee":"P. Tuo, J. Chen, and J. Li, “Flow matching for reaction pathway generation,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ista":"Tuo P, Chen J, Li J. 2026. Flow matching for reaction pathway generation. Nature Communications. 17, 8769.","apa":"Tuo, P., Chen, J., &#38; Li, J. (2026). Flow matching for reaction pathway generation. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-75654-w\">https://doi.org/10.1038/s41467-026-75654-w</a>","mla":"Tuo, Ping, et al. “Flow Matching for Reaction Pathway Generation.” <i>Nature Communications</i>, vol. 17, 8769, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-75654-w\">10.1038/s41467-026-75654-w</a>.","chicago":"Tuo, Ping, Jiale Chen, and Ju Li. “Flow Matching for Reaction Pathway Generation.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-75654-w\">https://doi.org/10.1038/s41467-026-75654-w</a>.","short":"P. Tuo, J. Chen, J. Li, Nature Communications 17 (2026)."},"month":"08","supplementarymaterial":"yes","file":[{"date_updated":"2026-09-09T07:25:19Z","date_created":"2026-09-09T07:25:19Z","creator":"dernst","file_name":"2026_NatureComm_Tuo.pdf","content_type":"application/pdf","access_level":"open_access","checksum":"3cfb714304eec29b97dcaf7fb86dd6e3","success":1,"file_size":1526298,"file_id":"22864","relation":"main_file"}],"date_published":"2026-08-21T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}],"title":"Flow matching for reaction pathway generation","author":[{"full_name":"Tuo, Ping","id":"6e5644c0-c180-11ed-a2da-facc4c9f4f09","first_name":"Ping","last_name":"Tuo"},{"id":"4d0a9064-1ff6-11ee-9fa6-ec046c604785","last_name":"Chen","first_name":"Jiale","orcid":"0000-0001-5337-5875","full_name":"Chen, Jiale"},{"full_name":"Li, Ju","last_name":"Li","first_name":"Ju"}],"OA_place":"publisher","volume":17,"OA_type":"gold","PlanS_conform":"1","pmid":1,"quality_controlled":"1","scopus_import":"1","intvolume":"        17","publication":"Nature Communications","_id":"22771","ddc":["000"],"das_tickbox":"1","article_type":"original","has_accepted_license":"1","date_created":"2026-08-30T22:01:43Z","oa":1,"publisher":"Springer Nature","DOAJ_listed":"1"},{"type":"research_data","keyword":["functional nanostructures","bistability","target behavior","transition pathway"],"day":"09","file_date_updated":"2026-09-08T18:36:14Z","citation":{"apa":"Ehrmann, A. (2026). Supplemental videos for Designing bistable nanostructures for target behavior. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22852\">https://doi.org/10.15479/AT-ISTA-22852</a>","ieee":"A. Ehrmann, “Supplemental videos for Designing bistable nanostructures for target behavior.” Institute of Science and Technology Austria, 2026.","ista":"Ehrmann A. 2026. Supplemental videos for Designing bistable nanostructures for target behavior, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-22852\">10.15479/AT-ISTA-22852</a>.","ama":"Ehrmann A. Supplemental videos for Designing bistable nanostructures for target behavior. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22852\">10.15479/AT-ISTA-22852</a>","mla":"Ehrmann, Andreas. <i>Supplemental Videos for Designing Bistable Nanostructures for Target Behavior</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22852\">10.15479/AT-ISTA-22852</a>.","chicago":"Ehrmann, Andreas. “Supplemental Videos for Designing Bistable Nanostructures for Target Behavior.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22852\">https://doi.org/10.15479/AT-ISTA-22852</a>.","short":"A. Ehrmann, (2026)."},"month":"09","doi":"10.15479/AT-ISTA-22852","status":"public","year":"2026","tmp":{"short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"abstract":[{"lang":"eng","text":"This Research Data contains supplemental videos for Chapter 4 \"Designing bistable nanostructures for target behavior\" of my PhD Thesis \"Biological functionality without biochemistry: designing nanomachines for target behavior\".\r\nSupplemental video 1: Video showing the transition pathway of a bistable nanostructure with sphere-based arms, corresponding to the Machine in Scenario 4.\r\nSupplemental video 2: Video showing the transition pathway of the Source in Scenario 1. The arm tips change sides during the transition, demonstrating that the arms pass through each other.\r\nSupplemental video 3: Video showing the transition pathway of a fully polyhedral hinge structure with unconstrained arms. Note that we only show the ends of the arms.\r\nSupplemental video 4: Video showing the transition pathway of the coupled energy-delivery reaction of a Machine (gray) and a Source (blue) nanostructure for the optimized parameters in Scenario 3. Note that we only show the ends of the arms."}],"fulldoi":"https://doi.org/10.15479/AT-ISTA-22852","department":[{"_id":"GradSch"},{"_id":"CaGo"},{"_id":"EdHa"}],"oa_version":"None","article_processing_charge":"No","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","date_updated":"2026-09-09T07:24:10Z","publisher":"Institute of Science and Technology Austria","doi_confirm":"1","_id":"22852","has_accepted_license":"1","contributor":[{"contributor_type":"data_collector","id":"eaa689ed-f6e0-11ea-865d-bd98cbcf83c2","last_name":"Ehrmann","first_name":"Andreas","orcid":"0000-0002-0997-5678"}],"project":[{"name":"Functional bio-inspired nanomachines from sticky colloids","grant_number":"PAT 8537123","_id":"90a98bb5-16d5-11f0-9cad-9675f3f8015d"}],"oa":1,"date_created":"2026-09-08T11:32:53Z","acknowledged_ssus":[{"_id":"ScienComp"}],"title":"Supplemental videos for Designing bistable nanostructures for target behavior","author":[{"orcid":"0000-0002-0997-5678","full_name":"Ehrmann, Andreas","id":"eaa689ed-f6e0-11ea-865d-bd98cbcf83c2","last_name":"Ehrmann","first_name":"Andreas"}],"OA_place":"repository","corr_author":"1","date_published":"2026-09-09T00:00:00Z","file":[{"date_updated":"2026-09-08T11:31:32Z","date_created":"2026-09-08T11:31:32Z","content_type":"video/mp4","file_name":"Supplemental video 1.mp4","creator":"aehrmann","checksum":"966417b3eab49523068bb0dfba4ecc07","access_level":"open_access","relation":"main_file","file_id":"22853","success":1,"file_size":1513964},{"content_type":"video/mp4","file_name":"Supplemental video 2.mp4","creator":"aehrmann","date_updated":"2026-09-08T11:31:37Z","date_created":"2026-09-08T11:31:37Z","relation":"main_file","file_id":"22854","file_size":2634179,"success":1,"checksum":"deddcae30875bff8e59d5dc9ee3c196f","access_level":"open_access"},{"creator":"aehrmann","file_name":"Supplemental video 3.mp4","content_type":"video/mp4","date_created":"2026-09-08T11:31:42Z","date_updated":"2026-09-08T11:31:42Z","success":1,"file_size":2080684,"file_id":"22855","relation":"main_file","checksum":"721446b7595edc670d877185637cf15c","access_level":"open_access"},{"date_updated":"2026-09-08T11:31:48Z","date_created":"2026-09-08T11:31:48Z","creator":"aehrmann","file_name":"Supplemental video 4.mp4","content_type":"video/mp4","checksum":"da44153821aa4f8f3cbc2860ef6d1bad","access_level":"open_access","file_size":4047831,"success":1,"file_id":"22856","relation":"main_file"},{"checksum":"1e94cd067809e1a93e21676181b4c102","access_level":"open_access","success":1,"file_size":1122,"file_id":"22860","relation":"main_file","date_updated":"2026-09-08T18:36:14Z","date_created":"2026-09-08T18:36:14Z","creator":"aehrmann","file_name":"README.txt","content_type":"text/plain"}]},{"type":"journal_article","day":"01","citation":{"ama":"Freunberger SA. Triggering conversion in vanadium electrodes. <i>Nature Materials</i>. 2026;25(9):1482-1483. doi:<a href=\"https://doi.org/10.1038/s41563-026-02714-3\">10.1038/s41563-026-02714-3</a>","apa":"Freunberger, S. A. (2026). Triggering conversion in vanadium electrodes. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-026-02714-3\">https://doi.org/10.1038/s41563-026-02714-3</a>","ieee":"S. A. Freunberger, “Triggering conversion in vanadium electrodes,” <i>Nature Materials</i>, vol. 25, no. 9. Springer Nature, pp. 1482–1483, 2026.","ista":"Freunberger SA. 2026. Triggering conversion in vanadium electrodes. Nature Materials. 25(9), 1482–1483.","short":"S.A. Freunberger, Nature Materials 25 (2026) 1482–1483.","mla":"Freunberger, Stefan Alexander. “Triggering Conversion in Vanadium Electrodes.” <i>Nature Materials</i>, vol. 25, no. 9, Springer Nature, 2026, pp. 1482–83, doi:<a href=\"https://doi.org/10.1038/s41563-026-02714-3\">10.1038/s41563-026-02714-3</a>.","chicago":"Freunberger, Stefan Alexander. “Triggering Conversion in Vanadium Electrodes.” <i>Nature Materials</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41563-026-02714-3\">https://doi.org/10.1038/s41563-026-02714-3</a>."},"month":"09","supplementarymaterial":"not applicable","doi":"10.1038/s41563-026-02714-3","publication_identifier":{"eissn":["1476-4660"],"issn":["1476-1122"]},"year":"2026","status":"public","abstract":[{"lang":"eng","text":"Using transition metals efficiently in aqueous batteries requires transferring multiple electrons per metal, which leads to difficult-to-manage conversion reactions. It is now shown how vanadium can be changed from one-electron insertion to four-electron conversion."}],"issue":"9","external_id":{"pmid":["42649374"]},"fulldoi":"https://doi.org/10.1038/s41563-026-02714-3","department":[{"_id":"StFr"}],"publication_status":"published","researchdata_availability":"not applicable","oa_version":"None","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-09-09T07:17:13Z","publisher":"Springer Nature","intvolume":"        25","scopus_import":"1","publication":"Nature Materials","_id":"22769","page":"1482-1483","das_tickbox":"0","article_type":"comment","date_created":"2026-08-26T18:48:33Z","author":[{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander"}],"title":"Triggering conversion in vanadium electrodes","volume":25,"OA_type":"closed access","pmid":1,"quality_controlled":"1","corr_author":"1","date_published":"2026-09-01T00:00:00Z","language":[{"iso":"eng"}]},{"supplementarymaterial":"yes","month":"08","citation":{"ista":"Wassermair M, Kahl G, Archer AJ, Roth R. 2026. Radial distribution function in a two-dimensional core-shoulder particle system. Journal of Physical Chemistry B. 130(33), 8514–8526.","ieee":"M. Wassermair, G. Kahl, A. J. Archer, and R. Roth, “Radial distribution function in a two-dimensional core-shoulder particle system,” <i>Journal of Physical Chemistry B</i>, vol. 130, no. 33. American Chemical Society, pp. 8514–8526, 2026.","apa":"Wassermair, M., Kahl, G., Archer, A. J., &#38; Roth, R. (2026). Radial distribution function in a two-dimensional core-shoulder particle system. <i>Journal of Physical Chemistry B</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.jpcb.6c00653\">https://doi.org/10.1021/acs.jpcb.6c00653</a>","ama":"Wassermair M, Kahl G, Archer AJ, Roth R. Radial distribution function in a two-dimensional core-shoulder particle system. <i>Journal of Physical Chemistry B</i>. 2026;130(33):8514-8526. doi:<a href=\"https://doi.org/10.1021/acs.jpcb.6c00653\">10.1021/acs.jpcb.6c00653</a>","mla":"Wassermair, Michael, et al. “Radial Distribution Function in a Two-Dimensional Core-Shoulder Particle System.” <i>Journal of Physical Chemistry B</i>, vol. 130, no. 33, American Chemical Society, 2026, pp. 8514–26, doi:<a href=\"https://doi.org/10.1021/acs.jpcb.6c00653\">10.1021/acs.jpcb.6c00653</a>.","chicago":"Wassermair, Michael, Gerhard Kahl, Andrew J. Archer, and Roland Roth. “Radial Distribution Function in a Two-Dimensional Core-Shoulder Particle System.” <i>Journal of Physical Chemistry B</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.jpcb.6c00653\">https://doi.org/10.1021/acs.jpcb.6c00653</a>.","short":"M. Wassermair, G. Kahl, A.J. Archer, R. Roth, Journal of Physical Chemistry B 130 (2026) 8514–8526."},"file_date_updated":"2026-09-09T11:05:02Z","type":"journal_article","day":"20","abstract":[{"text":"An important quantity in liquid state theory is the radial distribution function g(r). It can be calculated within the framework of classical density functional theory in two very distinct ways. In the test-particle route, one fixes a single fluid particle, turning it into an external potential in which the inhomogeneous structure of the fluid is calculated by minimizing the functional. The second route to g(r) in density functional theory employs the Ornstein–Zernike equation and the pair direct correlation function, that can be obtained from the second functional derivatives of the excess (over the ideal gas) free energy functional. Since typically an approximate excess free energy functional is employed, the test-particle route, which requires only one functional derivative, is more accurate than the Ornstein–Zernike route. Here we study a two-dimensional core-shoulder particle system and find that in some circumstances the results from the Ornstein–Zernike route can be comparable in accuracy to the test-particle results for r > σ, the core diameter. We also examine in detail the asymptotic r → ∞ decay of g(r), finding a variety of possible decay wavelengths at different state points and state points where there is a crossover from one wavelength to a very different one. This behavior is a signature pointing to the rich phase behavior of the incipient solid phases.","lang":"eng"}],"issue":"33","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"year":"2026","acknowledgement":"We are grateful to Florian Sanmüller and Matthias Schmidt for valuable comments on the manuscript and helpful discussions. The simulation results presented here were enabled via a generous allocation of CPU time by the Austrian Scientific Computing (ASC) under Project No. 71263. The authors thank Katrin Muck for her guidance related to the use of HPC. A.J.A. gratefully acknowledges support from the EPSRC under Grant No. EP/P015689/1. This research was funded in part by the Austrian Science Fund (FWF) under project no. PIN8759524 with Grant-DOI 10.55776/PIN8759524, gratefully acknowledged by GK.","status":"public","doi":"10.1021/acs.jpcb.6c00653","publication_identifier":{"eissn":["1520-5207"],"issn":["1520-6106"]},"publication_status":"published","researchdata_availability":"no","department":[{"_id":"AnSa"}],"fulldoi":"https://doi.org/10.1021/acs.jpcb.6c00653","external_id":{"pmid":["42622279"],"arxiv":["2603.24537"]},"date_updated":"2026-09-09T11:11:12Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes (in subscription journal)","oa_version":"Published Version","publisher":"American Chemical Society","oa":1,"date_created":"2026-08-30T22:01:44Z","article_type":"original","has_accepted_license":"1","_id":"22773","page":"8514-8526","das_tickbox":"0","ddc":["530","540"],"intvolume":"       130","scopus_import":"1","publication":"Journal of Physical Chemistry B","volume":130,"OA_type":"hybrid","PlanS_conform":"1","quality_controlled":"1","pmid":1,"OA_place":"publisher","author":[{"orcid":"0009-0003-6339-4051","full_name":"Wassermair, Michael","id":"23d132c4-4e98-11ef-b275-9e8d4cd8c917","last_name":"Wassermair","first_name":"Michael"},{"last_name":"Kahl","first_name":"Gerhard","full_name":"Kahl, Gerhard"},{"last_name":"Archer","first_name":"Andrew J.","full_name":"Archer, Andrew J."},{"last_name":"Roth","first_name":"Roland","full_name":"Roth, Roland"}],"title":"Radial distribution function in a two-dimensional core-shoulder particle system","arxiv":1,"language":[{"iso":"eng"}],"file":[{"access_level":"open_access","checksum":"67313d68ab13b553a38e8b4bf99983d2","relation":"main_file","file_id":"22871","success":1,"file_size":7472078,"date_updated":"2026-09-09T11:05:02Z","date_created":"2026-09-09T11:05:02Z","content_type":"application/pdf","creator":"dernst","file_name":"2026_JourPhysicChemistryB_Wassermair.pdf"}],"date_published":"2026-08-20T00:00:00Z","corr_author":"1"},{"scopus_import":"1","intvolume":"       708","publication":"Astronomy & Astrophysics","_id":"22815","das_tickbox":"0","ddc":["520"],"article_type":"original","has_accepted_license":"1","date_created":"2026-09-06T22:01:56Z","oa":1,"publisher":"EDP Sciences","DOAJ_listed":"1","file":[{"file_name":"2026_AstronomyAstrophysics_Pollock.pdf","creator":"dernst","content_type":"application/pdf","date_created":"2026-09-09T12:03:50Z","date_updated":"2026-09-09T12:03:50Z","success":1,"file_size":1854789,"file_id":"22874","relation":"main_file","access_level":"open_access","checksum":"4ab5af6fac257723afe2b7cf9fcbfa4c"}],"date_published":"2026-04-01T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}],"title":"Novel z ∼ 10 auroral line measurements extend the gradual offset of the fundamental metallicity relation deep into the first gigayear of cosmic time","author":[{"first_name":"Clara L.","last_name":"Pollock","full_name":"Pollock, Clara L."},{"first_name":"Rashmi","last_name":"Gottumukkala","full_name":"Gottumukkala, Rashmi"},{"full_name":"Heintz, Kasper E.","first_name":"Kasper E.","last_name":"Heintz"},{"first_name":"Gabriel B.","last_name":"Brammer","full_name":"Brammer, Gabriel B."},{"full_name":"Roberts-Borsani, Guido","last_name":"Roberts-Borsani","first_name":"Guido"},{"last_name":"Oesch","first_name":"Pascal A.","full_name":"Oesch, Pascal A."},{"first_name":"Joris","last_name":"Witstok","full_name":"Witstok, Joris"},{"full_name":"Arellano-Córdova, Karla Z.","last_name":"Arellano-Córdova","first_name":"Karla Z."},{"first_name":"Fergus","last_name":"Cullen","full_name":"Cullen, Fergus"},{"full_name":"Scholte, Dirk","last_name":"Scholte","first_name":"Dirk"},{"first_name":"Chamilla","last_name":"Terp","full_name":"Terp, Chamilla"},{"last_name":"Rowland","first_name":"Lucie","full_name":"Rowland, Lucie"},{"full_name":"Sneppen, Albert","last_name":"Sneppen","first_name":"Albert"},{"first_name":"Kei","last_name":"Ito","full_name":"Ito, Kei"},{"last_name":"Valentino","first_name":"Francesco","full_name":"Valentino, Francesco"},{"orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee"},{"full_name":"Watson, Darach","last_name":"Watson","first_name":"Darach"},{"first_name":"Sune","last_name":"Toft","full_name":"Toft, Sune"}],"OA_place":"publisher","volume":708,"OA_type":"gold","PlanS_conform":"1","quality_controlled":"1","doi":"10.1051/0004-6361/202556032","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"year":"2026","acknowledgement":"We would like to thank the referee for providing a comprehensive and constructive report, greatly improving the results presented in this work. We further express our greatest gratitude to the investigators on the major JWST observing programs, such as RUBIES, CAPERS, UNCOVER, and JADES. The work presented here would not have been possible without their major efforts in designing and obtaining the observational data included in our work here. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. The data products presented herein were retrieved from the DAWN JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center, which is funded by the Danish National Research Foundation under grant DNRF140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. This work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. Software used in this work includes MATPLOTLIB (Hunter 2007), NUMPY (Harris et al. 2020), SCIPY (Virtanen et al. 2020), and ASTROPY (Astropy Collaboration 2013).","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"The mass assembly and chemical enrichment of the first galaxies provide key insights into their star formation histories and the earliest stellar populations at cosmic dawn. Here we compile and utilise new, high-quality spectroscopic JWST/NIRSpec Prism observations from the JWST archive. In particular, we extend the wavelength coverage beyond the standard pipeline cut-off (5.3 μm) up to 5.5 μm, which enables for the first time a detailed examination of the rest-frame optical emission-line properties for galaxies at z ≈ 10. Crucially, the improved calibration allows us to detect Hβ and the [O III] λλ4959, 5007 doublet and resolve the auroral [O III] λ4363 line for the 11 galaxies in our sample (z = 9.3 − 10.0) to obtain direct Te-based metallicity measurements. We find that the interstellar medium (ISM) of all galaxies shows high ionisation fields and electron temperatures, with derived metallicities in the range 12 + log(O/H) = 7.1 − 8.3 (3–50% solar), consistent with previous strong-line diagnostics based on JWST data at high redshifts. We derive an empirical relation for MUV and 12 + log(O/H) at z ≈ 10, useful for future higher-redshift studies, and show that the sample galaxies are ‘typical’ star-forming galaxies though with relatively high specific star formation rates (median sSFR = SFRHβ/M★ = 38 Gyr−1) and with evidence of bursty star formation on 10 Myr versus 100 Myr timescales (log10(SFR10/SFR100)≈0.7). Combining the rest-frame optical line analysis and detailed UV to optical spectro-photometric modelling, we determine the mass-metallicity relation (MZR) and the fundamental metallicity relation (FMR) of the sample, pushing the previous redshift frontier of these measurements to z = 10. These results, together with literature measurements, point to a gradually decreasing MZR at higher redshifts, with a break in the FMR at z ≈ 3, decreasing to metallicities ≈3× lower at z = 10 than observed in galaxies during the majority of cosmic time at z = 0 − 3, likely caused by massive pristine gas inflows diluting the observed metal abundances during early galaxy assembly at cosmic dawn."}],"file_date_updated":"2026-09-09T12:03:50Z","type":"journal_article","day":"01","citation":{"ama":"Pollock CL, Gottumukkala R, Heintz KE, et al. Novel z ∼ 10 auroral line measurements extend the gradual offset of the fundamental metallicity relation deep into the first gigayear of cosmic time. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556032\">10.1051/0004-6361/202556032</a>","ista":"Pollock CL, Gottumukkala R, Heintz KE, Brammer GB, Roberts-Borsani G, Oesch PA, Witstok J, Arellano-Córdova KZ, Cullen F, Scholte D, Terp C, Rowland L, Sneppen A, Ito K, Valentino F, Matthee JJ, Watson D, Toft S. 2026. Novel z ∼ 10 auroral line measurements extend the gradual offset of the fundamental metallicity relation deep into the first gigayear of cosmic time. Astronomy &#38; Astrophysics. 708, A203.","apa":"Pollock, C. L., Gottumukkala, R., Heintz, K. E., Brammer, G. B., Roberts-Borsani, G., Oesch, P. A., … Toft, S. (2026). Novel z ∼ 10 auroral line measurements extend the gradual offset of the fundamental metallicity relation deep into the first gigayear of cosmic time. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556032\">https://doi.org/10.1051/0004-6361/202556032</a>","ieee":"C. L. Pollock <i>et al.</i>, “Novel z ∼ 10 auroral line measurements extend the gradual offset of the fundamental metallicity relation deep into the first gigayear of cosmic time,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026.","chicago":"Pollock, Clara L., Rashmi Gottumukkala, Kasper E. Heintz, Gabriel B. Brammer, Guido Roberts-Borsani, Pascal A. Oesch, Joris Witstok, et al. “Novel z ∼ 10 Auroral Line Measurements Extend the Gradual Offset of the Fundamental Metallicity Relation Deep into the First Gigayear of Cosmic Time.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556032\">https://doi.org/10.1051/0004-6361/202556032</a>.","mla":"Pollock, Clara L., et al. “Novel z ∼ 10 Auroral Line Measurements Extend the Gradual Offset of the Fundamental Metallicity Relation Deep into the First Gigayear of Cosmic Time.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A203, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556032\">10.1051/0004-6361/202556032</a>.","short":"C.L. Pollock, R. Gottumukkala, K.E. Heintz, G.B. Brammer, G. Roberts-Borsani, P.A. Oesch, J. Witstok, K.Z. Arellano-Córdova, F. Cullen, D. Scholte, C. Terp, L. Rowland, A. Sneppen, K. Ito, F. Valentino, J.J. Matthee, D. Watson, S. Toft, Astronomy &#38; Astrophysics 708 (2026)."},"supplementarymaterial":"no","month":"04","article_processing_charge":"Yes","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"A203","date_updated":"2026-09-09T12:07:45Z","external_id":{"arxiv":["2506.15779"]},"fulldoi":"https://doi.org/10.1051/0004-6361/202556032","department":[{"_id":"JoMa"}],"publication_status":"published","researchdata_availability":"no"},{"author":[{"first_name":"Rajagopal","last_name":"Varada","full_name":"Varada, Rajagopal"},{"first_name":"Alina F.","last_name":"Leuchtenberger","full_name":"Leuchtenberger, Alina F."},{"full_name":"Vesely, Cornelia","last_name":"Vesely","first_name":"Cornelia"},{"last_name":"Kaczmarek","first_name":"Beata M","id":"36FA4AFA-F248-11E8-B48F-1D18A9856A87","full_name":"Kaczmarek, Beata M"},{"full_name":"Mansouri Khosravi, Hamid","first_name":"Hamid","last_name":"Mansouri Khosravi"},{"last_name":"Mandl","first_name":"Therese C.","full_name":"Mandl, Therese C."},{"full_name":"Milanovic, Katarina","last_name":"Milanovic","first_name":"Katarina"},{"first_name":"Kasra","last_name":"Honarmand Tamizkar","full_name":"Honarmand Tamizkar, Kasra"},{"first_name":"Vinod","last_name":"Rajendra","full_name":"Rajendra, Vinod"},{"last_name":"Senoner","first_name":"Hannes","full_name":"Senoner, Hannes"},{"last_name":"Steinbichl","first_name":"Linda","full_name":"Steinbichl, Linda"},{"first_name":"Marija","last_name":"Borojevic","full_name":"Borojevic, Marija"},{"full_name":"Sombke, Andy","first_name":"Andy","last_name":"Sombke"},{"full_name":"Schmidt, Katy","first_name":"Katy","last_name":"Schmidt"},{"first_name":"Margret","last_name":"Eckhard","full_name":"Eckhard, Margret"},{"first_name":"Ivo L.","last_name":"Hofacker","full_name":"Hofacker, Ivo L."},{"full_name":"Walkley, Carl","last_name":"Walkley","first_name":"Carl"},{"first_name":"Jacki E.","last_name":"Heraud-Farlow","full_name":"Heraud-Farlow, Jacki E."},{"last_name":"Picardi","first_name":"Ernesto","full_name":"Picardi, Ernesto"},{"first_name":"Carrie A","last_name":"Bernecky","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","full_name":"Bernecky, Carrie A","orcid":"0000-0003-0893-7036"},{"full_name":"Jantsch, Michael F.","first_name":"Michael F.","last_name":"Jantsch"}],"title":"Distinguishing self from non-self RNA by editing-specific inosine patterns","OA_place":"publisher","OA_type":"gold","volume":54,"PlanS_conform":"1","pmid":1,"quality_controlled":"1","file":[{"checksum":"319904a237f73dcc55daa4a56baa98fa","access_level":"open_access","file_id":"22872","relation":"main_file","file_size":6016116,"success":1,"date_created":"2026-09-09T11:29:49Z","date_updated":"2026-09-09T11:29:49Z","content_type":"application/pdf","file_name":"2026_NucleicAcidsResearch_Varada.pdf","creator":"dernst"}],"date_published":"2026-09-09T00:00:00Z","language":[{"iso":"eng"}],"publisher":"Oxford University Press","DOAJ_listed":"1","intvolume":"        54","scopus_import":"1","publication":"Nucleic Acids Research","_id":"22772","ddc":["570"],"das_tickbox":"1","project":[{"name":"RNAdeco: decorating RNA for a purpose/ P03- Roles of A-to-I editing in dsRNA recognition","grant_number":"F8003","_id":"8dc144d4-16d5-11f0-9cad-9d9e86aea1f7"}],"article_type":"original","has_accepted_license":"1","oa":1,"date_created":"2026-08-30T22:01:44Z","external_id":{"pmid":["42635125"]},"fulldoi":"https://doi.org/10.1093/nar/gkag845","department":[{"_id":"CaBe"},{"_id":"GradSch"}],"researchdata_availability":"yes","publication_status":"published","oa_version":"Published Version","article_processing_charge":"Yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"gkag845","date_updated":"2026-09-09T11:31:04Z","dataavailabilitystatement":"Sequencing data has been deposited at GEO and is available under accession number GSE293616.\r\nEditing analysis of protected dsRNA is available in GitHub, https://github.com/BioinfoUNIBA/Mouse-dsRNA-mda5, and Zenodo, https://doi.org/10.5281/zenodo.17876716.","file_date_updated":"2026-09-09T11:29:49Z","type":"journal_article","day":"09","citation":{"short":"R. Varada, A.F. Leuchtenberger, C. Vesely, B.M. Kaczmarek, H. Mansouri Khosravi, T.C. Mandl, K. Milanovic, K. Honarmand Tamizkar, V. Rajendra, H. Senoner, L. Steinbichl, M. Borojevic, A. Sombke, K. Schmidt, M. Eckhard, I.L. Hofacker, C. Walkley, J.E. Heraud-Farlow, E. Picardi, C. Bernecky, M.F. Jantsch, Nucleic Acids Research 54 (2026).","chicago":"Varada, Rajagopal, Alina F. Leuchtenberger, Cornelia Vesely, Beata M Kaczmarek, Hamid Mansouri Khosravi, Therese C. Mandl, Katarina Milanovic, et al. “Distinguishing Self from Non-Self RNA by Editing-Specific Inosine Patterns.” <i>Nucleic Acids Research</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/nar/gkag845\">https://doi.org/10.1093/nar/gkag845</a>.","mla":"Varada, Rajagopal, et al. “Distinguishing Self from Non-Self RNA by Editing-Specific Inosine Patterns.” <i>Nucleic Acids Research</i>, vol. 54, no. 16, gkag845, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/nar/gkag845\">10.1093/nar/gkag845</a>.","ama":"Varada R, Leuchtenberger AF, Vesely C, et al. Distinguishing self from non-self RNA by editing-specific inosine patterns. <i>Nucleic Acids Research</i>. 2026;54(16). doi:<a href=\"https://doi.org/10.1093/nar/gkag845\">10.1093/nar/gkag845</a>","ista":"Varada R, Leuchtenberger AF, Vesely C, Kaczmarek BM, Mansouri Khosravi H, Mandl TC, Milanovic K, Honarmand Tamizkar K, Rajendra V, Senoner H, Steinbichl L, Borojevic M, Sombke A, Schmidt K, Eckhard M, Hofacker IL, Walkley C, Heraud-Farlow JE, Picardi E, Bernecky C, Jantsch MF. 2026. Distinguishing self from non-self RNA by editing-specific inosine patterns. Nucleic Acids Research. 54(16), gkag845.","ieee":"R. Varada <i>et al.</i>, “Distinguishing self from non-self RNA by editing-specific inosine patterns,” <i>Nucleic Acids Research</i>, vol. 54, no. 16. Oxford University Press, 2026.","apa":"Varada, R., Leuchtenberger, A. F., Vesely, C., Kaczmarek, B. M., Mansouri Khosravi, H., Mandl, T. C., … Jantsch, M. F. (2026). Distinguishing self from non-self RNA by editing-specific inosine patterns. <i>Nucleic Acids Research</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/nar/gkag845\">https://doi.org/10.1093/nar/gkag845</a>"},"supplementarymaterial":"yes","month":"09","doi":"10.1093/nar/gkag845","publication_identifier":{"eissn":["1362-4962"]},"year":"2026","status":"public","acknowledgement":"This work was supported by Austrian Science Fund project F80-07 to M.F.J., F80-03 to C.B., and ZK57-B28 to C.V.; National Health and Medical Research Council Australia (NHMRC; GNT2018098 to C.R.W.). The work was supported in part by the Victorian State Government Operational Infrastructure Support Scheme to St Vincent’s Institute and Hudson Institute of Medical Research. R.V. and A.L. were supported by Doc Fund/DOC32 of the Austrian Science Fund. Funding to pay the Open Access publication charges for this article was provided by Austrian Science Fund. For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"text":"The cytoplasmic antiviral sensor MDA5 is activated by double-stranded RNAs. Endogenous double-stranded RNAs are modified by the A-to-I RNA-editing ADAR family to prevent activation of MDA5. In vivo, cytoplasmic ADAR1p150 is critically required to suppress MDA5 activation, yet the editing signature of all ADAR isoforms is strongly overlapping in mice. Further, it is not clear how A-to-I modifications in dsRNA prevent MDA5 activation. Here we show that 3′ UTRs harboring inverted repeats activate MDA5 in vitro and in cells. In vitro editing by either ADAR isoform leads to editing at overlapping hotspot regions and prevents MDA5 activation in vitro and in cells. Remarkably, only inosines introduced by RNA editing are capable of suppressing MDA5 activation, while replacing guanosines with inosines during in vitro transcription has no impact on MDA5 activation. A comparison of inosines introduced by ADAR1p150 in vitro, in cells, and in vivo suggests that a small number of A-to-I conversions may be critically required to suppress MDA5 activation. As those critical editing events are predominantly altering A:U basepairs into I:U wobble basepairs, we suggest that the helical distortion introduced by those wobble pairs may prevent MDA5 polymerization and thus downstream activation of the type I interferon response.","lang":"eng"}],"issue":"16"},{"file_date_updated":"2026-09-09T12:19:36Z","type":"journal_article","day":"20","citation":{"short":"K.I. Caputi, R.A. Cooper, P. Rinaldi, R. Navarro-Carrera, E. Iani, A.A. Tumborang, The Astrophysical Journal 1007 (2026).","chicago":"Caputi, Karina I., Ryan A. Cooper, Pierluigi Rinaldi, Rafael Navarro-Carrera, Edoardo Iani, and Abigail A. Tumborang. “Pseudo Little Red Dot: An Active Black Hole Embedded in a Dense and Dusty, Metal-Poor Starburst Galaxy at z = 5.96.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae80b9\">https://doi.org/10.3847/1538-4357/ae80b9</a>.","mla":"Caputi, Karina I., et al. “Pseudo Little Red Dot: An Active Black Hole Embedded in a Dense and Dusty, Metal-Poor Starburst Galaxy at z = 5.96.” <i>The Astrophysical Journal</i>, vol. 1007, no. 2, 203, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae80b9\">10.3847/1538-4357/ae80b9</a>.","ama":"Caputi KI, Cooper RA, Rinaldi P, Navarro-Carrera R, Iani E, Tumborang AA. Pseudo Little Red Dot: An active black hole embedded in a dense and dusty, metal-poor starburst galaxy at z = 5.96. <i>The Astrophysical Journal</i>. 2026;1007(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae80b9\">10.3847/1538-4357/ae80b9</a>","ieee":"K. I. Caputi, R. A. Cooper, P. Rinaldi, R. Navarro-Carrera, E. Iani, and A. A. Tumborang, “Pseudo Little Red Dot: An active black hole embedded in a dense and dusty, metal-poor starburst galaxy at z = 5.96,” <i>The Astrophysical Journal</i>, vol. 1007, no. 2. IOP Publishing, 2026.","ista":"Caputi KI, Cooper RA, Rinaldi P, Navarro-Carrera R, Iani E, Tumborang AA. 2026. Pseudo Little Red Dot: An active black hole embedded in a dense and dusty, metal-poor starburst galaxy at z = 5.96. The Astrophysical Journal. 1007(2), 203.","apa":"Caputi, K. I., Cooper, R. A., Rinaldi, P., Navarro-Carrera, R., Iani, E., &#38; Tumborang, A. A. (2026). Pseudo Little Red Dot: An active black hole embedded in a dense and dusty, metal-poor starburst galaxy at z = 5.96. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae80b9\">https://doi.org/10.3847/1538-4357/ae80b9</a>"},"month":"08","supplementarymaterial":"no","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"doi":"10.3847/1538-4357/ae80b9","year":"2026","status":"public","acknowledgement":"We are grateful to Daniela Calzetti, Andrea Ferrara, Kohei Inayoshi, Roberto Maiolino, Gabriele Pezzulli, Fengwu Sun, and Z. Yan for useful discussions; José M. Diego for providing us the most updated magnification value for our source; Raphael Hviding for making his Python package unite public and instructing us regarding its use; and Elka Rusta and Stefania Salvadori for providing us their galaxy SED models with hybrid Pop III stellar populations. We also thank the anonymous referee for a useful and constructive report.\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with the JWST GTO program PID 1208. The specific observations analyzed here can be accessed via doi:10.17909/pyr9-5r43. Some of the analyzed data products were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. This work is also based on observations made with the NASA/ESA Hubble Space Telescope obtained from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 526555.\r\n\r\nK.I.C. and R.N.C. acknowledge funding from the Dutch Research Council (NWO) through the award of the Vici grant VI.C.212.036.","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"We present a study of a pseudo little red dot with no metal lines (Pseudo-LRD-NOM), a highly magnified lowmass galaxy behind the lensing cluster A370 at z = 5.96. We classify this object as a pseudo-LRD because its red\r\nrest-frame optical color is contaminated by a prominent Hα line (with EW0 ≳ 800 Å) present in its JWST\r\nNIRSpec spectrum. Hα is dominated by a narrow component and also has a minor broad component indicative of\r\nan active black hole with MBH ≈ 5.6 × 10^6 M⊙. A narrow Hβ emission line is also detected (where the signal-tonoise ratio, S/N, is 8), producing a Balmer decrement (narrow) Hα/Hβ = 11. The rest-frame UV spectral slope is ßspec/uv = - 1.20 ± 0.28. All these features can be ascribed to high dust attenuation. However, no [O III]λ5007 or\r\nany other metal lines are detected in the spectrum, so [O III]5007/Hβ < 0.25, at odds with a simple dust attenuation explanation. Accounting for all the spectral properties requires the model of a starburst with moderate\r\ncolor excess E(B − V )≈0.2–0.5, high gas density (nH ≳ 10^6 cm^−3\r\n), and low- to extremely-low gas/stellar\r\nmetallicities (Z = 0.01–0.1 Z⊙). The demagnified stellar mass is\r\n× 2.25+\r\n0\r\n1\r\n.\r\n.\r\n8\r\n3\r\n3\r\n0 10^7 M , and the stellar-mass surface\r\ndensity is = +\r\n* 418 M pc 310\r\n725 2, similar to that of massive/nuclear star clusters. Pseudo-LRD-NOM provides\r\nevidence of massive black-hole growth occurring in a high-density, dusty starburst that is at the early stages of its\r\nchemical enrichment, and is likely a precursor to a real LRD."}],"issue":"2","external_id":{"arxiv":["2601.11466"]},"fulldoi":"https://doi.org/10.3847/1538-4357/ae80b9","department":[{"_id":"JoMa"}],"researchdata_availability":"no","publication_status":"published","article_processing_charge":"Yes","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"203","date_updated":"2026-09-09T12:19:54Z","publisher":"IOP Publishing","DOAJ_listed":"1","intvolume":"      1007","scopus_import":"1","publication":"The Astrophysical Journal","_id":"22814","das_tickbox":"0","ddc":["520"],"article_type":"original","has_accepted_license":"1","date_created":"2026-09-06T22:01:56Z","oa":1,"author":[{"full_name":"Caputi, Karina I.","last_name":"Caputi","first_name":"Karina I."},{"full_name":"Cooper, Ryan A.","first_name":"Ryan A.","last_name":"Cooper"},{"full_name":"Rinaldi, Pierluigi","first_name":"Pierluigi","last_name":"Rinaldi"},{"full_name":"Navarro-Carrera, Rafael","last_name":"Navarro-Carrera","first_name":"Rafael"},{"orcid":"0000-0001-8386-3546","full_name":"Iani, Edoardo","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a","first_name":"Edoardo","last_name":"Iani"},{"full_name":"Tumborang, Abigail A.","first_name":"Abigail A.","last_name":"Tumborang"}],"title":"Pseudo Little Red Dot: An active black hole embedded in a dense and dusty, metal-poor starburst galaxy at z = 5.96","OA_place":"publisher","OA_type":"gold","volume":1007,"quality_controlled":"1","file":[{"checksum":"cf878372382ac61b22f679b558bb4e4e","access_level":"open_access","file_id":"22887","relation":"main_file","file_size":2636477,"success":1,"date_updated":"2026-09-09T12:19:36Z","date_created":"2026-09-09T12:19:36Z","content_type":"application/pdf","creator":"dernst","file_name":"2026_AstrophysicalJour_Caputi.pdf"}],"date_published":"2026-08-20T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}]},{"article_type":"original","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"name":"The design and evaluation of modern fully dynamic data structures","call_identifier":"H2020","grant_number":"101019564","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62"}],"date_created":"2026-09-06T22:01:55Z","publication":"Information Processing Letters","intvolume":"       195","scopus_import":"1","das_tickbox":"1","_id":"22812","publisher":"Elsevier","language":[{"iso":"eng"}],"date_published":"2026-08-30T00:00:00Z","quality_controlled":"1","OA_type":"closed access","volume":195,"title":"Tight bounds on the performance of dynamic directed cutset data structures based on OMv","author":[{"first_name":"Niklas","last_name":"Hahn","id":"0a01c7b2-b823-11ed-9928-cc3f874f9ffd","full_name":"Hahn, Niklas"},{"id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","first_name":"Monika H","orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H"},{"first_name":"Zofia","last_name":"Stefankovic","full_name":"Stefankovic, Zofia"}],"abstract":[{"text":"Efficient data structures for computing the cutset of a set of nodes in a graph undergoing dynamic edge insertions/deletions are well-studied in undirected graphs. We study this problem in directed graphs and show a reduction from the Online Boolean Matrix-Vector Multiplication Conjecture (OMv) introduced by Henzinger et al. [STOC’15]. We prove conditional on OMv that a dynamic data structure computing the directed cutset of a set of nodes cannot have an amortized time of both O(n2−ε) for a query operation and O(n1−ε) for an update operation, for any constant ε > 0, even when an adversary’s operations are restricted to the incremental or decremental settings. We further give algorithms to match these lower bounds.","lang":"eng"}],"doi":"10.1016/j.ipl.2026.106663","publication_identifier":{"issn":["0020-0190"]},"status":"public","acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413 and from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (MoDynStruct, No. 101019564) Image 1 dummy alt text. Zofia Stefankovic was partially supported by the ISTernship program of the Institute of Science and Technology Austria and OEAD.","year":"2026","citation":{"ista":"Hahn N, Henzinger M, Stefankovic Z. 2026. Tight bounds on the performance of dynamic directed cutset data structures based on OMv. Information Processing Letters. 195, 106663.","apa":"Hahn, N., Henzinger, M., &#38; Stefankovic, Z. (2026). Tight bounds on the performance of dynamic directed cutset data structures based on OMv. <i>Information Processing Letters</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ipl.2026.106663\">https://doi.org/10.1016/j.ipl.2026.106663</a>","ieee":"N. Hahn, M. Henzinger, and Z. Stefankovic, “Tight bounds on the performance of dynamic directed cutset data structures based on OMv,” <i>Information Processing Letters</i>, vol. 195. Elsevier, 2026.","ama":"Hahn N, Henzinger M, Stefankovic Z. Tight bounds on the performance of dynamic directed cutset data structures based on OMv. <i>Information Processing Letters</i>. 2026;195. doi:<a href=\"https://doi.org/10.1016/j.ipl.2026.106663\">10.1016/j.ipl.2026.106663</a>","chicago":"Hahn, Niklas, Monika Henzinger, and Zofia Stefankovic. “Tight Bounds on the Performance of Dynamic Directed Cutset Data Structures Based on OMv.” <i>Information Processing Letters</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ipl.2026.106663\">https://doi.org/10.1016/j.ipl.2026.106663</a>.","mla":"Hahn, Niklas, et al. “Tight Bounds on the Performance of Dynamic Directed Cutset Data Structures Based on OMv.” <i>Information Processing Letters</i>, vol. 195, 106663, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ipl.2026.106663\">10.1016/j.ipl.2026.106663</a>.","short":"N. Hahn, M. Henzinger, Z. Stefankovic, Information Processing Letters 195 (2026)."},"month":"08","supplementarymaterial":"no","ec_funded":1,"dataavailabilitystatement":"No data was used for the research described in the article.","type":"journal_article","day":"30","keyword":["Dynamic algorithms","Graph algorithms","Directed graphs","Lower bounds","Upper bounds"],"date_updated":"2026-09-09T11:55:47Z","article_number":"106663","article_processing_charge":"No","oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"MoHe"}],"researchdata_availability":"no","publication_status":"epub_ahead","fulldoi":"https://doi.org/10.1016/j.ipl.2026.106663"},{"intvolume":"       407","scopus_import":"1","publication":"Communications in Mathematical Physics","_id":"22813","ddc":["500"],"das_tickbox":"1","article_type":"original","project":[{"_id":"bd95085b-d553-11ed-ba76-e55d3349be45","grant_number":"101076777","name":"Randomness and structure in combinatorics"}],"has_accepted_license":"1","oa":1,"date_created":"2026-09-06T22:01:56Z","publisher":"Springer","file":[{"date_created":"2026-09-09T12:32:53Z","date_updated":"2026-09-09T12:32:53Z","creator":"dernst","file_name":"2026_CommMathPhysics_Jain.pdf","content_type":"application/pdf","checksum":"61c226b6314a88db25e864e4218d5de3","access_level":"open_access","file_size":463477,"success":1,"relation":"main_file","file_id":"22888"}],"corr_author":"1","date_published":"2026-08-28T00:00:00Z","arxiv":1,"language":[{"iso":"eng"}],"author":[{"full_name":"Jain, Vishesh","last_name":"Jain","first_name":"Vishesh"},{"id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3","last_name":"Kwan","first_name":"Matthew Alan","orcid":"0000-0002-4003-7567","full_name":"Kwan, Matthew Alan"},{"last_name":"Michelen","first_name":"Marcus","full_name":"Michelen, Marcus"}],"title":"Entangled states are typically incomparable","OA_place":"publisher","PlanS_conform":"1","volume":407,"OA_type":"hybrid","quality_controlled":"1","pmid":1,"publication_identifier":{"eissn":["1432-0916"],"issn":["0010-3616"]},"doi":"10.1007/s00220-026-05711-4","year":"2026","status":"public","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). Vishesh Jain was partially supported by NSF CAREER award DMS-2237646. Matthew Kwan was supported by ERC Starting Grant “RANDSTRUCT” No. 101076777. Marcus Michelen was supported in part by NSF grants DMS-2137623 and DMS-2246624.","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Consider a bipartite quantum system, where Alice and Bob jointly possess\r\na pure state |ψ\u0002. Using local quantum operations on their respective subsystems, and\r\nunlimited classical communication, Alice and Bob may be able to transform |ψ\u0002 into\r\nanother state |φ\u0002. Famously, Nielsen’s theorem [28] provides a necessary and sufficient\r\nalgebraic criterion for such a transformation to be possible (namely, the entanglement\r\nspectrum of |φ\u0002 should majorise the entanglement spectrum of |ψ\u0002). In the paper where\r\nNielsen proved this theorem, he conjectured that in the limit of large dimensionality, for\r\nalmost all pairs of states |ψ\u0002, |φ\u0002 (according to the natural unitary invariant measure) such\r\na transformation is not possible. That is to say, typical pairs of quantum states |ψ\u0002, |φ\u0002\r\nare entangled in fundamentally different ways, that cannot be converted to each other via\r\nlocal operations and classical communication.ViaNielsen’s theorem, this conjecture can\r\nbe equivalently stated as a conjecture about majorisation of spectra of random matrices\r\nfrom the so-called trace-normalised complex Wishart–Laguerre ensemble. Concretely,\r\nlet X and Y be independent n × m random matrices whose entries are i.i.d. standard\r\ncomplex Gaussians; then Nielsen’s conjecture says that the probability that the spectrum\r\nof XX†/ tr(XX†) majorises the spectrum of YY†/ tr(YY†) tends to zero as both n and\r\nm grow large. We prove this conjecture, and we also confirm some related predictions\r\nof Cunden et al. [12]."}],"issue":"10","dataavailabilitystatement":"No datasets were used in this research.","file_date_updated":"2026-09-09T12:32:53Z","type":"journal_article","day":"28","citation":{"short":"V. Jain, M.A. Kwan, M. Michelen, Communications in Mathematical Physics 407 (2026).","mla":"Jain, Vishesh, et al. “Entangled States Are Typically Incomparable.” <i>Communications in Mathematical Physics</i>, vol. 407, no. 10, 214, Springer, 2026, doi:<a href=\"https://doi.org/10.1007/s00220-026-05711-4\">10.1007/s00220-026-05711-4</a>.","chicago":"Jain, Vishesh, Matthew Alan Kwan, and Marcus Michelen. “Entangled States Are Typically Incomparable.” <i>Communications in Mathematical Physics</i>. Springer, 2026. <a href=\"https://doi.org/10.1007/s00220-026-05711-4\">https://doi.org/10.1007/s00220-026-05711-4</a>.","ieee":"V. Jain, M. A. Kwan, and M. Michelen, “Entangled states are typically incomparable,” <i>Communications in Mathematical Physics</i>, vol. 407, no. 10. Springer, 2026.","ista":"Jain V, Kwan MA, Michelen M. 2026. Entangled states are typically incomparable. Communications in Mathematical Physics. 407(10), 214.","apa":"Jain, V., Kwan, M. A., &#38; Michelen, M. (2026). Entangled states are typically incomparable. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-026-05711-4\">https://doi.org/10.1007/s00220-026-05711-4</a>","ama":"Jain V, Kwan MA, Michelen M. Entangled states are typically incomparable. <i>Communications in Mathematical Physics</i>. 2026;407(10). doi:<a href=\"https://doi.org/10.1007/s00220-026-05711-4\">10.1007/s00220-026-05711-4</a>"},"supplementarymaterial":"no","month":"08","oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"214","date_updated":"2026-09-09T12:35:24Z","external_id":{"pmid":["42668663"],"arxiv":["2406.03335"]},"fulldoi":"https://doi.org/10.1007/s00220-026-05711-4","department":[{"_id":"MaKw"}],"researchdata_availability":"no","publication_status":"published"},{"department":[{"_id":"CaMu"},{"_id":"GradSch"}],"researchdata_availability":"upon request","publication_status":"epub_ahead","fulldoi":"https://doi.org/10.1002/qj.70280","date_updated":"2026-09-09T12:43:30Z","article_number":"e70280","oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"A. Davin, G.A. Charinti, C.J. Muller, A. Polesello, C. Pasquero, Quarterly Journal of the Royal Meteorological Society (2026).","mla":"Davin, Andrea, et al. “Stratospheric Influence on Tropical Cyclone Evolution.” <i>Quarterly Journal of the Royal Meteorological Society</i>, e70280, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/qj.70280\">10.1002/qj.70280</a>.","chicago":"Davin, Andrea, Giousef Alexandros Charinti, Caroline J Muller, Andrea Polesello, and Claudia Pasquero. “Stratospheric Influence on Tropical Cyclone Evolution.” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/qj.70280\">https://doi.org/10.1002/qj.70280</a>.","ista":"Davin A, Charinti GA, Muller CJ, Polesello A, Pasquero C. 2026. Stratospheric influence on tropical cyclone evolution. Quarterly Journal of the Royal Meteorological Society., e70280.","ieee":"A. Davin, G. A. Charinti, C. J. Muller, A. Polesello, and C. Pasquero, “Stratospheric influence on tropical cyclone evolution,” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026.","ama":"Davin A, Charinti GA, Muller CJ, Polesello A, Pasquero C. Stratospheric influence on tropical cyclone evolution. <i>Quarterly Journal of the Royal Meteorological Society</i>. 2026. doi:<a href=\"https://doi.org/10.1002/qj.70280\">10.1002/qj.70280</a>","apa":"Davin, A., Charinti, G. A., Muller, C. J., Polesello, A., &#38; Pasquero, C. (2026). Stratospheric influence on tropical cyclone evolution. <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley. <a href=\"https://doi.org/10.1002/qj.70280\">https://doi.org/10.1002/qj.70280</a>"},"month":"08","supplementarymaterial":"yes","ec_funded":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/qj.70280"}],"dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author upon reasonable request.","day":"26","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Physical processes at play in the genesis and evolution of tropical cyclones are conducive to the formation of warm cores at their centres. When the warm anomaly is particularly large in the upper troposphere, it is referred to as a high-level warm core. Previous works documented the generation of high-level warm cores as a consequence of stratospheric air intrusion into the troposphere induced by the upper-level dynamics of a tropical cyclone. However, little attention has been given to their effects on the storm's subsequent evolution. It has been suggested that the presence of a high-level warm core can have opposite effects on tropical cyclone intensity: both strengthening and weakening have been described as possible consequences of its formation. In this study, we examine the role of high-level warm cores in the intensification and dissipation processes of tropical cyclones, as reproduced in numerical models of different complexities, namely the model “System for Atmospheric Modeling” (SAM) run under idealized conditions and the model Nonhydrostatic ICosahedral Atmospheric Model run under realistic conditions following the DYnamics of the Atmospheric general circulation Modeled On Non-hydrostatic Domains summer protocol. Our results confirm the hypothesis of a stratospheric origin behind the formation of high-level warm cores. Their initial role is shown to be an enhancement of storm intensity, by a lowering of the hydrostatic sea-level pressure (HSLP) associated with the presence of warm air aloft. However, as the warm anomaly intensifies and extends to lower levels, it also increases static stability in the air column, with the consequence of inhibiting convection and ultimately contributing to cyclone dissipation. These findings suggest that high-level warm cores play a dual role in the tropical cyclone life cycle, providing a stabilizing mechanism that can limit cyclone strength and longevity."}],"publication_identifier":{"issn":["0035-9009"],"eissn":["1477-870X"]},"doi":"10.1002/qj.70280","status":"public","acknowledgement":"The authors thank Tom Beucler, Hamish Ramsay, and two anonymous reviewers for insightful comments and constructive feedback on earlier versions of this work.\r\n\r\nThis work is partially funded by the National Recovery and Resilience Plan project TeRABIT (Terabit network for Research and Academic Big data in Italy—IR0000022—PNRRMissione4—Componente2—Investim ento3.1—CUPI53C21000370006) in the frame of the European Union—NextGenerationEU funding. C. Muller gratefully acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant 805041). This work is an outcome of the project MIUR—Dipartimenti di Eccellenza 2023–2027.\r\n\r\nThis work used resources of the Deutsches Klimarechenzentrum (DKRZ) granted by its Scientific Steering Committee (WLA) under project bb1153. Open access publishing facilitated by Universita degli Studi di Milano-Bicocca, as part of the Wiley - CRUI-CARE agreement.","year":"2026","OA_place":"publisher","quality_controlled":"1","OA_type":"hybrid","title":"Stratospheric influence on tropical cyclone evolution","author":[{"full_name":"Davin, Andrea","first_name":"Andrea","last_name":"Davin"},{"id":"7f7cc04c-074c-11ed-af92-eb16afd85c75","first_name":"Giousef Alexandros","last_name":"Charinti","full_name":"Charinti, Giousef Alexandros"},{"full_name":"Muller, Caroline J","orcid":"0000-0001-5836-5350","first_name":"Caroline J","last_name":"Muller","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b"},{"full_name":"Polesello, Andrea","last_name":"Polesello","first_name":"Andrea","id":"74c777f4-32da-11ee-b498-874db0835561"},{"first_name":"Claudia","last_name":"Pasquero","full_name":"Pasquero, Claudia"}],"language":[{"iso":"eng"}],"date_published":"2026-08-26T00:00:00Z","publisher":"Wiley","has_accepted_license":"1","project":[{"grant_number":"805041","_id":"629205d8-2b32-11ec-9570-e1356ff73576","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","call_identifier":"H2020"}],"article_type":"original","oa":1,"date_created":"2026-09-06T22:01:57Z","publication":"Quarterly Journal of the Royal Meteorological Society","scopus_import":"1","ddc":["550"],"das_tickbox":"1","_id":"22818"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","article_processing_charge":"No","date_updated":"2026-09-09T12:59:51Z","article_number":"A242","fulldoi":"https://doi.org/10.1051/0004-6361/202556832","external_id":{"arxiv":["2601.06968"]},"publication_status":"published","researchdata_availability":"yes","department":[{"_id":"JoMa"}],"acknowledgement":"Y.I., N.G., R.M.-C., and D.S. acknowledge support from\r\nproject No. 224866 carried out in the framework of the Joint Call “UkrainianSwiss Joint Research Projects: Call for Proposals 2023”. This work is based in\r\npart on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes\r\nat the Space Telescope Science Institute, which is operated by the Association\r\nof Universities for Research in Astronomy, Inc., under NASA contract NAS 5-\r\n03127 for JWST. These observations are associated with program # 1869. Support for program # 1869 was provided by NASA through a grant from the Space\r\nTelescope Science Institute, which is operated by the Association of Universities\r\nfor Research in Astronomy, Inc., under NASA contract NAS 5-03127","status":"public","year":"2026","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"doi":"10.1051/0004-6361/202556832","abstract":[{"text":"Using deep, medium-resolution, JWST rest-optical spectra of a sample of typical star-forming galaxies (Lyman-break galaxies and Lyman-α emitters) from the LyC22 survey at z ∼ 3, we determined the nebular abundances of N, O, and Ne relative to H for a subsample of 25 objects with a direct method based on auroral [O III] λ4363 line detections. Our measurements increased the number of accurate N/O determinations at z ∼ 2 − 4 using a homogeneous approach. We found a mean value of log(N/O) = −+0.25−0.21 over a metallicity range of 12 + log(O/H) = 7.56 to 8.44. The observed N/O ratio and scatter are indistinguishable from that observed in low-z galaxies and H II regions over the same metallicity range, thus showing no redshift evolution of N/O for typical galaxies over a significant fraction of cosmic time. We also show that typical z ∼ 3 galaxies have a similar offset in the BPT diagram to galaxies from the low-z Lyman Continuum Survey (LzLCS) when compared to the average of SDSS galaxies, and we demonstrate that this offset is not due to enhanced nitrogen abundances. Our results establish a basis for future studies of the evolution of N and O at higher redshifts.","lang":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"type":"journal_article","day":"01","file_date_updated":"2026-09-09T12:55:37Z","dataavailabilitystatement":"The data used are publicly available at the Mikulski Archive for Space Telescope (MAST),\r\nand can be accessed at https://dx.doi.org/10.17909/x6d5-vd44.","supplementarymaterial":"no","month":"04","citation":{"mla":"Schaerer, D., et al. “Nitrogen Abundances in Star-Forming Galaxies 2.2 Gyr after the Big Bang Are Not Elevated.” <i>Astronomy &#38; Astrophysics</i>, vol. 708, A242, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556832\">10.1051/0004-6361/202556832</a>.","chicago":"Schaerer, D., Y. I. Izotov, R. Marques-Chaves, C. C. Steidel, N. Reddy, A. E. Shapley, Sara Mascia, et al. “Nitrogen Abundances in Star-Forming Galaxies 2.2 Gyr after the Big Bang Are Not Elevated.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556832\">https://doi.org/10.1051/0004-6361/202556832</a>.","short":"D. Schaerer, Y.I. Izotov, R. Marques-Chaves, C.C. Steidel, N. Reddy, A.E. Shapley, S. Mascia, J. Chisholm, S.R. Flury, N. Guseva, T. Heckman, A. Henry, A.K. Inoue, I. Jung, H. Kusakabe, K. Mawatari, P. Oesch, G. Östlin, L. Pentericci, N. Roy, A. Saldana-Lopez, R. Sato, E. Vanzella, A. Verhamme, B. Wang, Astronomy &#38; Astrophysics 708 (2026).","apa":"Schaerer, D., Izotov, Y. I., Marques-Chaves, R., Steidel, C. C., Reddy, N., Shapley, A. E., … Wang, B. (2026). Nitrogen abundances in star-forming galaxies 2.2 Gyr after the Big Bang are not elevated. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556832\">https://doi.org/10.1051/0004-6361/202556832</a>","ama":"Schaerer D, Izotov YI, Marques-Chaves R, et al. Nitrogen abundances in star-forming galaxies 2.2 Gyr after the Big Bang are not elevated. <i>Astronomy &#38; Astrophysics</i>. 2026;708. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556832\">10.1051/0004-6361/202556832</a>","ista":"Schaerer D, Izotov YI, Marques-Chaves R, Steidel CC, Reddy N, Shapley AE, Mascia S, Chisholm J, Flury SR, Guseva N, Heckman T, Henry A, Inoue AK, Jung I, Kusakabe H, Mawatari K, Oesch P, Östlin G, Pentericci L, Roy N, Saldana-Lopez A, Sato R, Vanzella E, Verhamme A, Wang B. 2026. Nitrogen abundances in star-forming galaxies 2.2 Gyr after the Big Bang are not elevated. Astronomy &#38; Astrophysics. 708, A242.","ieee":"D. Schaerer <i>et al.</i>, “Nitrogen abundances in star-forming galaxies 2.2 Gyr after the Big Bang are not elevated,” <i>Astronomy &#38; Astrophysics</i>, vol. 708. EDP Sciences, 2026."},"date_published":"2026-04-01T00:00:00Z","file":[{"file_size":591297,"success":1,"file_id":"22890","relation":"main_file","access_level":"open_access","checksum":"94cc1327f363d69995984b06e18e2645","creator":"dernst","file_name":"2026_AstronomyAstrophysics_Schaerer.pdf","content_type":"application/pdf","date_created":"2026-09-09T12:55:37Z","date_updated":"2026-09-09T12:55:37Z"}],"language":[{"iso":"eng"}],"arxiv":1,"title":"Nitrogen abundances in star-forming galaxies 2.2 Gyr after the Big Bang are not elevated","author":[{"last_name":"Schaerer","first_name":"D.","full_name":"Schaerer, D."},{"last_name":"Izotov","first_name":"Y. I.","full_name":"Izotov, Y. I."},{"first_name":"R.","last_name":"Marques-Chaves","full_name":"Marques-Chaves, R."},{"full_name":"Steidel, C. C.","first_name":"C. C.","last_name":"Steidel"},{"full_name":"Reddy, N.","last_name":"Reddy","first_name":"N."},{"first_name":"A. E.","last_name":"Shapley","full_name":"Shapley, A. E."},{"first_name":"Sara","last_name":"Mascia","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","full_name":"Mascia, Sara"},{"first_name":"J.","last_name":"Chisholm","full_name":"Chisholm, J."},{"full_name":"Flury, S. R.","last_name":"Flury","first_name":"S. R."},{"full_name":"Guseva, N.","last_name":"Guseva","first_name":"N."},{"last_name":"Heckman","first_name":"T.","full_name":"Heckman, T."},{"last_name":"Henry","first_name":"A.","full_name":"Henry, A."},{"full_name":"Inoue, A. K.","first_name":"A. K.","last_name":"Inoue"},{"full_name":"Jung, I.","last_name":"Jung","first_name":"I."},{"last_name":"Kusakabe","first_name":"H.","full_name":"Kusakabe, H."},{"last_name":"Mawatari","first_name":"K.","full_name":"Mawatari, K."},{"first_name":"P.","last_name":"Oesch","full_name":"Oesch, P."},{"full_name":"Östlin, G.","first_name":"G.","last_name":"Östlin"},{"first_name":"L.","last_name":"Pentericci","full_name":"Pentericci, L."},{"first_name":"N.","last_name":"Roy","full_name":"Roy, N."},{"full_name":"Saldana-Lopez, A.","last_name":"Saldana-Lopez","first_name":"A."},{"last_name":"Sato","first_name":"R.","full_name":"Sato, R."},{"first_name":"E.","last_name":"Vanzella","full_name":"Vanzella, E."},{"last_name":"Verhamme","first_name":"A.","full_name":"Verhamme, A."},{"full_name":"Wang, B.","last_name":"Wang","first_name":"B."}],"quality_controlled":"1","PlanS_conform":"1","OA_type":"diamond","volume":708,"OA_place":"publisher","das_tickbox":"1","ddc":["520"],"_id":"22817","publication":"Astronomy & Astrophysics","intvolume":"       708","scopus_import":"1","date_created":"2026-09-06T22:01:57Z","oa":1,"has_accepted_license":"1","article_type":"original","DOAJ_listed":"1","publisher":"EDP Sciences"},{"publication_identifier":{"issn":["1613-6810"],"eissn":["1613-6829"]},"doi":"10.1002/smll.75437","year":"2026","acknowledgement":"SS sincerely acknowledges the fellowship received from the Ministryof Education, Government of India, to carry out this research. SKRacknowledges the financial support from DST Nano-mission (Projectno. DST/NM/TUE/QM8 2019G 5). The authors also thank the CentralResearch Facility (CRF) at IIT Kharagpur for providing the characteriza-tion tools.","status":"public","abstract":[{"text":"Bio-inspired photonic synapses integrate optical sensing, memory, and processing in a single platform, overcoming the bottlenecks of traditional CMOS-based vision sensors. Most existing neuromorphic vision systems either rely on electrical inputs for bidirectional conductance modulation, limiting their operating speed and bandwidth, or lack nonvolatility, leading to nonlinear weight updates and poor efficiency in image recognition tasks. Here, we report a two-terminal, fully light-controlled synaptic memristor based on CsPbBr3/ZnO nanorod heterojunction that demonstrates 4-bit memory storage and optical logic operations within a single architecture. The device emulates essential functions of both excitatory and inhibitory synapses, utilizing positive photoconductivity under UV illumination (λ = 375 nm) and anomalous negative photoconductivity under visible light (λ = 450 nm). By controlling defect concentrations at the CsPbBr3/ZnO nanorod interface, the device exhibits nonvolatile multibit memory with near-linear, symmetric conductance modulation, achieving 92.4% image recognition accuracy with a convolutional neural network. The bidirectional photoresponse enables reconfigurable optical logic operations, demonstrating integrated logic-in-memory. Additionally, when integrated on a flexible platform, the device demonstrates stable synaptic performance under repeated mechanical bending. These results highlight the potential of CsPbBr3/ZnO nanorod heterojunction-based all-photonic synapses as building blocks for multibit storage, optical information processing, and wearable neuromorphic vision systems.","lang":"eng"}],"dataavailabilitystatement":"The data that support the findings of this study are available in theSupporting Information of this article.","day":"25","keyword":["all-optical synapse","bidirectional photoresponse","defect engineering","flexible neuromorphic vision","multibit nonvolatile memory","negativephotoconductivity","optical logic gate"],"type":"journal_article","citation":{"chicago":"Saha, Subham, Shreyasi Das, Baidyanath Roy, Santu Kumar Ghosh, Rohit Satpathy, James Bullock, Ranjith R. Unnithan, and Samit K. Ray. “Interface Engineered Perovskite-Oxide Heterojunction All-Photonic Synapses for Multibit Memory, Optical Logic, and Wearable Neuromorphic Vision.” <i>Small</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/smll.75437\">https://doi.org/10.1002/smll.75437</a>.","mla":"Saha, Subham, et al. “Interface Engineered Perovskite-Oxide Heterojunction All-Photonic Synapses for Multibit Memory, Optical Logic, and Wearable Neuromorphic Vision.” <i>Small</i>, e75437, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/smll.75437\">10.1002/smll.75437</a>.","short":"S. Saha, S. Das, B. Roy, S.K. Ghosh, R. Satpathy, J. Bullock, R.R. Unnithan, S.K. Ray, Small (2026).","apa":"Saha, S., Das, S., Roy, B., Ghosh, S. K., Satpathy, R., Bullock, J., … Ray, S. K. (2026). Interface engineered perovskite-oxide heterojunction all-photonic synapses for multibit memory, optical logic, and wearable neuromorphic vision. <i>Small</i>. Wiley. <a href=\"https://doi.org/10.1002/smll.75437\">https://doi.org/10.1002/smll.75437</a>","ieee":"S. Saha <i>et al.</i>, “Interface engineered perovskite-oxide heterojunction all-photonic synapses for multibit memory, optical logic, and wearable neuromorphic vision,” <i>Small</i>. Wiley, 2026.","ista":"Saha S, Das S, Roy B, Ghosh SK, Satpathy R, Bullock J, Unnithan RR, Ray SK. 2026. Interface engineered perovskite-oxide heterojunction all-photonic synapses for multibit memory, optical logic, and wearable neuromorphic vision. Small., e75437.","ama":"Saha S, Das S, Roy B, et al. Interface engineered perovskite-oxide heterojunction all-photonic synapses for multibit memory, optical logic, and wearable neuromorphic vision. <i>Small</i>. 2026. doi:<a href=\"https://doi.org/10.1002/smll.75437\">10.1002/smll.75437</a>"},"month":"08","supplementarymaterial":"yes","article_processing_charge":"No","oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e75437","date_updated":"2026-09-09T13:40:30Z","external_id":{"pmid":["42643004"]},"fulldoi":"https://doi.org/10.1002/smll.75437","department":[{"_id":"HrPo"}],"researchdata_availability":"no","publication_status":"epub_ahead","scopus_import":"1","publication":"Small","_id":"22819","das_tickbox":"1","date_created":"2026-09-06T22:01:58Z","publisher":"Wiley","date_published":"2026-08-25T00:00:00Z","language":[{"iso":"eng"}],"title":"Interface engineered perovskite-oxide heterojunction all-photonic synapses for multibit memory, optical logic, and wearable neuromorphic vision","author":[{"first_name":"Subham","last_name":"Saha","full_name":"Saha, Subham"},{"id":"c102f9d5-4f26-11ef-94d5-9047d2a9105b","last_name":"Das","first_name":"Shreyasi","full_name":"Das, Shreyasi"},{"full_name":"Roy, Baidyanath","last_name":"Roy","first_name":"Baidyanath"},{"first_name":"Santu Kumar","last_name":"Ghosh","full_name":"Ghosh, Santu Kumar"},{"full_name":"Satpathy, Rohit","first_name":"Rohit","last_name":"Satpathy"},{"first_name":"James","last_name":"Bullock","full_name":"Bullock, James"},{"last_name":"Unnithan","first_name":"Ranjith R.","full_name":"Unnithan, Ranjith R."},{"last_name":"Ray","first_name":"Samit K.","full_name":"Ray, Samit K."}],"OA_type":"closed access","pmid":1,"quality_controlled":"1"},{"citation":{"ista":"Browning TD, Sofos E, Teräväinen J. 2026. Bateman-Horn, polynomial Chowla and the Hasse principle with probability. Journal für die reine und angewandte Mathematik.","apa":"Browning, T. D., Sofos, E., &#38; Teräväinen, J. (2026). Bateman-Horn, polynomial Chowla and the Hasse principle with probability. <i>Journal Für Die Reine Und Angewandte Mathematik</i>. De Gruyter. <a href=\"https://doi.org/10.1515/crelle-2026-0062\">https://doi.org/10.1515/crelle-2026-0062</a>","ama":"Browning TD, Sofos E, Teräväinen J. Bateman-Horn, polynomial Chowla and the Hasse principle with probability. <i>Journal für die reine und angewandte Mathematik</i>. 2026. doi:<a href=\"https://doi.org/10.1515/crelle-2026-0062\">10.1515/crelle-2026-0062</a>","ieee":"T. D. Browning, E. Sofos, and J. Teräväinen, “Bateman-Horn, polynomial Chowla and the Hasse principle with probability,” <i>Journal für die reine und angewandte Mathematik</i>. De Gruyter, 2026.","short":"T.D. Browning, E. Sofos, J. Teräväinen, Journal Für Die Reine Und Angewandte Mathematik (2026).","mla":"Browning, Timothy D., et al. “Bateman-Horn, Polynomial Chowla and the Hasse Principle with Probability.” <i>Journal Für Die Reine Und Angewandte Mathematik</i>, De Gruyter, 2026, doi:<a href=\"https://doi.org/10.1515/crelle-2026-0062\">10.1515/crelle-2026-0062</a>.","chicago":"Browning, Timothy D, Efthymios Sofos, and Joni Teräväinen. “Bateman-Horn, Polynomial Chowla and the Hasse Principle with Probability.” <i>Journal Für Die Reine Und Angewandte Mathematik</i>. De Gruyter, 2026. <a href=\"https://doi.org/10.1515/crelle-2026-0062\">https://doi.org/10.1515/crelle-2026-0062</a>."},"month":"08","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2212.10373","open_access":"1"}],"type":"journal_article","day":"25","abstract":[{"lang":"eng","text":"With probability 1, we assess the average behaviour of various arithmetic functions at the values of degree 𝑑 polynomials 𝑓∈ℤ⁢[𝑡] that are ordered by height. This allows us to establish averaged versions of the Bateman–Horn conjecture, the polynomial Chowla conjecture and to address a basic question about the integral Hasse principle for norm form equations. Moreover, we are able to quantify the error term in the asymptotics and the size of the exceptional set of 𝑓, both with arbitrary logarithmic power savings."}],"publication_identifier":{"issn":["0075-4102"],"eissn":["1435-5345"]},"doi":"10.1515/crelle-2026-0062","status":"public","acknowledgement":"Tim Browning was supported by an FWF grant (DOI 10.55776/P32428), Efthymios Sofos was supported by EPSRC New Horizons grant EP/V048236/1, and Joni Teräväinen was supported by Academy of Finland grant no. 340098, a von Neumann Fellowship (NSF grant DMS-1926686), and funding from European Union’s Horizon Europe research and innovation programme under Marie Skłodowska-Curie grant agreement no. 101058904. This material is based upon work supported by a grant from the Institute for Advanced Study School of Mathematics. The authors are extremely grateful to the anonymous referee and to Yijie Diao for useful comments.","year":"2026","department":[{"_id":"TiBr"}],"publication_status":"epub_ahead","external_id":{"arxiv":["2212.10373"]},"fulldoi":"https://doi.org/10.1515/crelle-2026-0062","date_updated":"2026-09-09T13:28:45Z","oa_version":"Preprint","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"De Gruyter","project":[{"call_identifier":"FWF","name":"New frontiers of the Manin conjecture","_id":"26AEDAB2-B435-11E9-9278-68D0E5697425","grant_number":"P32428"}],"article_type":"original","oa":1,"date_created":"2026-09-06T22:01:58Z","publication":"Journal für die reine und angewandte Mathematik","scopus_import":"1","_id":"22821","OA_place":"repository","quality_controlled":"1","OA_type":"green","author":[{"orcid":"0000-0002-8314-0177","full_name":"Browning, Timothy D","id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning"},{"full_name":"Sofos, Efthymios","last_name":"Sofos","first_name":"Efthymios"},{"first_name":"Joni","last_name":"Teräväinen","full_name":"Teräväinen, Joni"}],"title":"Bateman-Horn, polynomial Chowla and the Hasse principle with probability","language":[{"iso":"eng"}],"arxiv":1,"date_published":"2026-08-25T00:00:00Z","corr_author":"1"}]