[{"author":[{"last_name":"Ford","full_name":"Ford, Bryan","first_name":"Bryan"},{"first_name":"Linus","full_name":"Gasse, Linus","last_name":"Gasse"},{"last_name":"Kokoris Kogias","first_name":"Eleftherios","full_name":"Kokoris Kogias, Eleftherios","id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30"},{"last_name":"Jovanovic","full_name":"Jovanovic, Philipp","first_name":"Philipp"}],"application_date":"2017-06-09","department":[{"_id":"ElKo"}],"type":"patent","main_file_link":[{"open_access":"1","url":"https://patents.google.com/patent/US10581613B2/en"}],"date_published":"2020-03-03T00:00:00Z","day":"03","extern":"1","oa":1,"citation":{"mla":"Ford, Bryan, et al. <i>Cryptographically Verifiable Data Structure Having Multi-Hop Forward and Backwards Links and Associated Systems and Methods</i>. 2020.","apa":"Ford, B., Gasse, L., Kokoris Kogias, E., &#38; Jovanovic, P. (2020). Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods.","ieee":"B. Ford, L. Gasse, E. Kokoris Kogias, and P. Jovanovic, “Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods.” 2020.","chicago":"Ford, Bryan, Linus Gasse, Eleftherios Kokoris Kogias, and Philipp Jovanovic. “Cryptographically Verifiable Data Structure Having Multi-Hop Forward and Backwards Links and Associated Systems and Methods,” 2020.","short":"B. Ford, L. Gasse, E. Kokoris Kogias, P. Jovanovic, (2020).","ama":"Ford B, Gasse L, Kokoris Kogias E, Jovanovic P. Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods. 2020.","ista":"Ford B, Gasse L, Kokoris Kogias E, Jovanovic P. 2020. Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods."},"applicant":["Ecole Polytechnique Federale de Lausanne"],"date_created":"2021-12-16T13:28:59Z","status":"public","oa_version":"Published Version","related_material":{"link":[{"url":"https://patents.google.com/patent/US20180359096A1/en","relation":"earlier_version"}]},"month":"03","_id":"10557","abstract":[{"text":"Data storage and retrieval systems, methods, and computer-readable media utilize a cryptographically verifiable data structure that facilitates verification of a transaction in a decentralized peer-to-peer environment using multi-hop backwards and forwards links. Backward links are cryptographic hashes of past records. Forward links are cryptographic signatures of future records that are added retroactively to records once the target block has been appended to the data structure.","lang":"eng"}],"date_updated":"2021-12-21T10:04:50Z","year":"2020","title":"Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","article_processing_charge":"No","publication_date":"2020-03-03","ipn":"10581613","ipc":" H04L9/3247 ; G06Q20/29 ; G06Q20/382 ; H04L9/3236"},{"intvolume":"       588","citation":{"ieee":"H. Polshyn <i>et al.</i>, “Electrical switching of magnetic order in an orbital Chern insulator,” <i>Nature</i>, vol. 588, no. 7836. Springer Nature, pp. 66–70, 2020.","apa":"Polshyn, H., Zhu, J., Kumar, M. A., Zhang, Y., Yang, F., Tschirhart, C. L., … Young, A. F. (2020). Electrical switching of magnetic order in an orbital Chern insulator. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-020-2963-8\">https://doi.org/10.1038/s41586-020-2963-8</a>","mla":"Polshyn, Hryhoriy, et al. “Electrical Switching of Magnetic Order in an Orbital Chern Insulator.” <i>Nature</i>, vol. 588, no. 7836, Springer Nature, 2020, pp. 66–70, doi:<a href=\"https://doi.org/10.1038/s41586-020-2963-8\">10.1038/s41586-020-2963-8</a>.","ista":"Polshyn H, Zhu J, Kumar MA, Zhang Y, Yang F, Tschirhart CL, Serlin M, Watanabe K, Taniguchi T, MacDonald AH, Young AF. 2020. Electrical switching of magnetic order in an orbital Chern insulator. Nature. 588(7836), 66–70.","ama":"Polshyn H, Zhu J, Kumar MA, et al. Electrical switching of magnetic order in an orbital Chern insulator. <i>Nature</i>. 2020;588(7836):66-70. doi:<a href=\"https://doi.org/10.1038/s41586-020-2963-8\">10.1038/s41586-020-2963-8</a>","short":"H. Polshyn, J. Zhu, M.A. Kumar, Y. Zhang, F. Yang, C.L. Tschirhart, M. Serlin, K. Watanabe, T. Taniguchi, A.H. MacDonald, A.F. Young, Nature 588 (2020) 66–70.","chicago":"Polshyn, Hryhoriy, J. Zhu, M. A. Kumar, Y. Zhang, F. Yang, C. L. Tschirhart, M. Serlin, et al. “Electrical Switching of Magnetic Order in an Orbital Chern Insulator.” <i>Nature</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41586-020-2963-8\">https://doi.org/10.1038/s41586-020-2963-8</a>."},"publication_status":"published","_id":"10618","month":"11","arxiv":1,"scopus_import":"1","publisher":"Springer Nature","publication":"Nature","type":"journal_article","day":"23","extern":"1","issue":"7836","page":"66-70","external_id":{"arxiv":["2004.11353"],"pmid":["33230333"]},"date_updated":"2022-01-13T14:21:04Z","year":"2020","language":[{"iso":"eng"}],"doi":"10.1038/s41586-020-2963-8","date_created":"2022-01-13T14:12:17Z","status":"public","quality_controlled":"1","oa_version":"Preprint","abstract":[{"text":"Magnetism typically arises from the joint effect of Fermi statistics and repulsive Coulomb interactions, which favours ground states with non-zero electron spin. As a result, controlling spin magnetism with electric fields—a longstanding technological goal in spintronics and multiferroics1,2—can be achieved only indirectly. Here we experimentally demonstrate direct electric-field control of magnetic states in an orbital Chern insulator3,4,5,6, a magnetic system in which non-trivial band topology favours long-range order of orbital angular momentum but the spins are thought to remain disordered7,8,9,10,11,12,13,14. We use van der Waals heterostructures consisting of a graphene monolayer rotationally faulted with respect to a Bernal-stacked bilayer to realize narrow and topologically non-trivial valley-projected moiré minibands15,16,17. At fillings of one and three electrons per moiré unit cell within these bands, we observe quantized anomalous Hall effects18 with transverse resistance approximately equal to h/2e2 (where h is Planck’s constant and e is the charge on the electron), which is indicative of spontaneous polarization of the system into a single-valley-projected band with a Chern number equal to two. At a filling of three electrons per moiré unit cell, we find that the sign of the quantum anomalous Hall effect can be reversed via field-effect control of the chemical potential; moreover, this transition is hysteretic, which we use to demonstrate non-volatile electric-field-induced reversal of the magnetic state. A theoretical analysis19 indicates that the effect arises from the topological edge states, which drive a change in sign of the magnetization and thus a reversal in the favoured magnetic state. Voltage control of magnetic states can be used to electrically pattern non-volatile magnetic-domain structures hosting chiral edge states, with applications ranging from reconfigurable microwave circuit elements to ultralow-power magnetic memories.","lang":"eng"}],"author":[{"orcid":"0000-0001-8223-8896","last_name":"Polshyn","first_name":"Hryhoriy","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"first_name":"J.","full_name":"Zhu, J.","last_name":"Zhu"},{"first_name":"M. A.","full_name":"Kumar, M. A.","last_name":"Kumar"},{"full_name":"Zhang, Y.","first_name":"Y.","last_name":"Zhang"},{"full_name":"Yang, F.","first_name":"F.","last_name":"Yang"},{"first_name":"C. L.","full_name":"Tschirhart, C. L.","last_name":"Tschirhart"},{"first_name":"M.","full_name":"Serlin, M.","last_name":"Serlin"},{"last_name":"Watanabe","first_name":"K.","full_name":"Watanabe, K."},{"first_name":"T.","full_name":"Taniguchi, T.","last_name":"Taniguchi"},{"first_name":"A. H.","full_name":"MacDonald, A. H.","last_name":"MacDonald"},{"full_name":"Young, A. F.","first_name":"A. F.","last_name":"Young"}],"keyword":["multidisciplinary"],"main_file_link":[{"url":"https://arxiv.org/abs/2004.11353","open_access":"1"}],"date_published":"2020-11-23T00:00:00Z","oa":1,"volume":588,"article_processing_charge":"No","pmid":1,"publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"acknowledgement":"We acknowledge discussions with J. Checkelsky, S. Chen, C. Dean, M. Yankowitz, D. Reilly, I. Sodemann and M. Zaletel. Work at UCSB was primarily supported by the ARO under MURI W911NF-16-1-0361. Measurements of twisted bilayer graphene (Extended Data Fig. 8) and measurements at elevated temperatures (Extended Data Fig. 3) were supported by a SEED grant and made use of shared facilities of the UCSB MRSEC (NSF DMR 1720256), a member of the Materials Research Facilities Network (www.mrfn.org). A.F.Y. acknowledges the support of the David and Lucille Packard Foundation under award 2016-65145. A.H.M. and J.Z. were supported by the National Science Foundation through the Center for Dynamics and Control of Materials, an NSF MRSEC under Cooperative Agreement number DMR-1720595, and by the Welch Foundation under grant TBF1473. C.L.T. acknowledges support from the Hertz Foundation and from the National Science Foundation Graduate Research Fellowship Program under grant 1650114. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by the MEXT, Japan, Grant Number JPMXP0112101001, JSPS KAKENHI grant numbers JP20H00354 and the CREST(JPMJCR15F3), JST.","article_type":"original","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Electrical switching of magnetic order in an orbital Chern insulator"},{"day":"01","oa":1,"extern":"1","publication":"arXiv","date_published":"2020-10-01T00:00:00Z","type":"preprint","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2010.00584"}],"author":[{"last_name":"Alexandradinata","first_name":"A","full_name":"Alexandradinata, A"},{"last_name":"Armitage","full_name":"Armitage, N.P.","first_name":"N.P."},{"last_name":"Baydin","first_name":"Andrey","full_name":"Baydin, Andrey"},{"last_name":"Bi","full_name":"Bi, Wenli","first_name":"Wenli"},{"first_name":"Yue","full_name":"Cao, Yue","last_name":"Cao"},{"last_name":"Changlani","full_name":"Changlani, Hitesh J.","first_name":"Hitesh J."},{"last_name":"Chertkov","full_name":"Chertkov, Eli","first_name":"Eli"},{"last_name":"da Silva Neto","first_name":"Eduardo H.","full_name":"da Silva Neto, Eduardo H."},{"last_name":"Delacretaz","full_name":"Delacretaz, Luca","first_name":"Luca"},{"first_name":"Ismail","full_name":"El Baggari, Ismail","last_name":"El Baggari"},{"last_name":"Ferguson","first_name":"G.M.","full_name":"Ferguson, G.M."},{"first_name":"William J.","full_name":"Gannon, William J.","last_name":"Gannon"},{"last_name":"Ghorashi","first_name":"Sayed Ali Akbar","full_name":"Ghorashi, Sayed Ali Akbar"},{"last_name":"Goodge","first_name":"Berit H.","full_name":"Goodge, Berit H."},{"last_name":"Goulko","full_name":"Goulko, Olga","first_name":"Olga"},{"first_name":"G.","full_name":"Grissonnache, G.","last_name":"Grissonnache"},{"full_name":"Hallas, Alannah","first_name":"Alannah","last_name":"Hallas"},{"full_name":"Hayes, Ian M.","first_name":"Ian M.","last_name":"Hayes"},{"last_name":"He","full_name":"He, Yu","first_name":"Yu"},{"last_name":"Huang","full_name":"Huang, Edwin W.","first_name":"Edwin W."},{"full_name":"Kogar, Anshu","first_name":"Anshu","last_name":"Kogar"},{"full_name":"Kumah, Divine","first_name":"Divine","last_name":"Kumah"},{"last_name":"Lee","full_name":"Lee, Jong Yeon","first_name":"Jong Yeon"},{"full_name":"Legros, A.","first_name":"A.","last_name":"Legros"},{"last_name":"Mahmood","full_name":"Mahmood, Fahad","first_name":"Fahad"},{"last_name":"Maximenko","full_name":"Maximenko, Yulia","first_name":"Yulia"},{"last_name":"Pellatz","full_name":"Pellatz, Nick","first_name":"Nick"},{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"first_name":"Tarapada","full_name":"Sarkar, Tarapada","last_name":"Sarkar"},{"full_name":"Scheie, Allen","first_name":"Allen","last_name":"Scheie"},{"first_name":"Kyle L.","full_name":"Seyler, Kyle L.","last_name":"Seyler"},{"last_name":"Shi","full_name":"Shi, Zhenzhong","first_name":"Zhenzhong"},{"full_name":"Skinner, Brian","first_name":"Brian","last_name":"Skinner"},{"first_name":"Lucia","full_name":"Steinke, Lucia","last_name":"Steinke"},{"full_name":"Thirunavukkuarasu, K.","first_name":"K.","last_name":"Thirunavukkuarasu"},{"last_name":"Trevisan","first_name":"Thaís Victa","full_name":"Trevisan, Thaís Victa"},{"first_name":"Michael","full_name":"Vogl, Michael","last_name":"Vogl"},{"last_name":"Volkov","full_name":"Volkov, Pavel A.","first_name":"Pavel A."},{"full_name":"Wang, Yao","first_name":"Yao","last_name":"Wang"},{"full_name":"Wang, Yishu","first_name":"Yishu","last_name":"Wang"},{"full_name":"Wei, Di","first_name":"Di","last_name":"Wei"},{"first_name":"Kaya","full_name":"Wei, Kaya","last_name":"Wei"},{"full_name":"Yang, Shuolong","first_name":"Shuolong","last_name":"Yang"},{"last_name":"Zhang","full_name":"Zhang, Xian","first_name":"Xian"},{"full_name":"Zhang, Ya-Hui","first_name":"Ya-Hui","last_name":"Zhang"},{"full_name":"Zhao, Liuyan","first_name":"Liuyan","last_name":"Zhao"},{"first_name":"Alfred","full_name":"Zong, Alfred","last_name":"Zong"}],"_id":"10650","month":"10","abstract":[{"text":"The understanding of material systems with strong electron-electron interactions is the central problem in modern condensed matter physics. Despite this, the essential physics of many of these materials is still not understood and we have no overall perspective on their properties. Moreover, we have very little ability to make predictions in this class of systems. In this manuscript we share our personal views of what the major open problems are in correlated electron systems and we discuss some possible routes to make progress in this rich and fascinating field. This manuscript is the result of the vigorous discussions and deliberations that took place at Johns Hopkins University during a three-day workshop January 27, 28, and 29, 2020 that brought together six senior scientists and 46 more junior scientists. Our hope, is that the topics we have presented will provide inspiration for others working in this field and motivation for the idea that significant progress can be made on very hard problems if we focus our collective energies.","lang":"eng"}],"arxiv":1,"oa_version":"Preprint","status":"public","date_created":"2022-01-20T10:55:36Z","language":[{"iso":"eng"}],"citation":{"short":"A. Alexandradinata, N.P. Armitage, A. Baydin, W. Bi, Y. Cao, H.J. Changlani, E. Chertkov, E.H. da Silva Neto, L. Delacretaz, I. El Baggari, G.M. Ferguson, W.J. Gannon, S.A.A. Ghorashi, B.H. Goodge, O. Goulko, G. Grissonnache, A. Hallas, I.M. Hayes, Y. He, E.W. Huang, A. Kogar, D. Kumah, J.Y. Lee, A. Legros, F. Mahmood, Y. Maximenko, N. Pellatz, H. Polshyn, T. Sarkar, A. Scheie, K.L. Seyler, Z. Shi, B. Skinner, L. Steinke, K. Thirunavukkuarasu, T.V. Trevisan, M. Vogl, P.A. Volkov, Y. Wang, Y. Wang, D. Wei, K. Wei, S. Yang, X. Zhang, Y.-H. Zhang, L. Zhao, A. Zong, ArXiv (n.d.).","chicago":"Alexandradinata, A, N.P. Armitage, Andrey Baydin, Wenli Bi, Yue Cao, Hitesh J. Changlani, Eli Chertkov, et al. “The Future of the Correlated Electron Problem.” <i>ArXiv</i>, n.d.","ista":"Alexandradinata A, Armitage NP, Baydin A, Bi W, Cao Y, Changlani HJ, Chertkov E, da Silva Neto EH, Delacretaz L, El Baggari I, Ferguson GM, Gannon WJ, Ghorashi SAA, Goodge BH, Goulko O, Grissonnache G, Hallas A, Hayes IM, He Y, Huang EW, Kogar A, Kumah D, Lee JY, Legros A, Mahmood F, Maximenko Y, Pellatz N, Polshyn H, Sarkar T, Scheie A, Seyler KL, Shi Z, Skinner B, Steinke L, Thirunavukkuarasu K, Trevisan TV, Vogl M, Volkov PA, Wang Y, Wang Y, Wei D, Wei K, Yang S, Zhang X, Zhang Y-H, Zhao L, Zong A. The future of the correlated electron problem. arXiv, .","ama":"Alexandradinata A, Armitage NP, Baydin A, et al. The future of the correlated electron problem. <i>arXiv</i>.","apa":"Alexandradinata, A., Armitage, N. P., Baydin, A., Bi, W., Cao, Y., Changlani, H. J., … Zong, A. (n.d.). The future of the correlated electron problem. <i>arXiv</i>.","mla":"Alexandradinata, A., et al. “The Future of the Correlated Electron Problem.” <i>ArXiv</i>.","ieee":"A. Alexandradinata <i>et al.</i>, “The future of the correlated electron problem,” <i>arXiv</i>. ."},"publication_status":"submitted","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"The future of the correlated electron problem","year":"2020","external_id":{"arxiv":["2010.00584"]},"date_updated":"2022-01-24T08:05:51Z","acknowledgement":"We thank NSF CMP program for suggestions regarding the topic and general structure of the workshop. This project was supported by the NSF DMR-2002329 and The Gordon and Betty Moore Foundation (GBMF) EPiQS initiative. We would like to sincerely thank A. Kapitulnik, A. J. Leggett, M.B. Maple, T.M. McQueen, M. Norman, P. S. Riseborough, and G. A. Sawatzky for their lectures at the workshop and advice on the writing of this manuscript. We would also like to thank G. Blumberg, C. Broholm, S. Crooker, N. Drichko, and A. Patel for helpful consultation on topics discussed\r\nherein. A number of individuals also had independent support: (AA, EH; GBMF-4305), (IMH; GBMF-9071), (HJC; NHMFL is supported by the NSF DMR-1644779 and the state of Florida), (YH, AZ; Miller Institute for Basic Research in Science), (YC; US DOE-BES DEAC02-06CH11357), (AS; Spallation Neutron Source, a DOE Office of Science User Facility operated by ORNL), (SAAG; ARO-W911NF-18-1-0290, NSF DMR-1455233), (YW; DOE-BES DE-SC0019331, GBMF-4532).","page":"55","article_processing_charge":"No"},{"author":[{"last_name":"Lechner","id":"3DC22916-F248-11E8-B48F-1D18A9856A87","full_name":"Lechner, Mathias","first_name":"Mathias"}],"ddc":["000"],"oa":1,"file_date_updated":"2022-01-26T07:35:17Z","date_published":"2020-03-11T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://openreview.net/forum?id=Bke61krFvS"}],"status":"public","date_created":"2022-01-25T15:50:00Z","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"The family of feedback alignment (FA) algorithms aims to provide a more biologically motivated alternative to backpropagation (BP), by substituting the computations that are unrealistic to be implemented in physical brains. While FA algorithms have been shown to work well in practice, there is a lack of rigorous theory proofing their learning capabilities. Here we introduce the first feedback alignment algorithm with provable learning guarantees. In contrast to existing work, we do not require any assumption about the size or depth of the network except that it has a single output neuron, i.e., such as for binary classification tasks. We show that our FA algorithm can deliver its theoretical promises in practice, surpassing the learning performance of existing FA methods and matching backpropagation in binary classification tasks. Finally, we demonstrate the limits of our FA variant when the number of output neurons grows beyond a certain quantity."}],"quality_controlled":"1","project":[{"call_identifier":"FWF","name":"Formal methods for the design and analysis of complex systems","grant_number":"Z211","_id":"25F42A32-B435-11E9-9278-68D0E5697425"}],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Learning representations for binary-classification without backpropagation","article_processing_charge":"No","has_accepted_license":"1","acknowledgement":"This research was supported in part by the Austrian Science Fund (FWF) under grant Z211-N23\r\n(Wittgenstein Award).\r\n","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","short":"CC BY-NC-ND (3.0)"},"department":[{"_id":"GradSch"},{"_id":"ToHe"}],"publisher":"ICLR","license":"https://creativecommons.org/licenses/by-nc-nd/3.0/","day":"11","publication":"8th International Conference on Learning Representations","type":"conference","publication_status":"published","citation":{"ieee":"M. Lechner, “Learning representations for binary-classification without backpropagation,” in <i>8th International Conference on Learning Representations</i>, Virtual ; Addis Ababa, Ethiopia, 2020.","mla":"Lechner, Mathias. “Learning Representations for Binary-Classification without Backpropagation.” <i>8th International Conference on Learning Representations</i>, ICLR, 2020.","apa":"Lechner, M. (2020). Learning representations for binary-classification without backpropagation. In <i>8th International Conference on Learning Representations</i>. Virtual ; Addis Ababa, Ethiopia: ICLR.","ama":"Lechner M. Learning representations for binary-classification without backpropagation. In: <i>8th International Conference on Learning Representations</i>. ICLR; 2020.","ista":"Lechner M. 2020. Learning representations for binary-classification without backpropagation. 8th International Conference on Learning Representations. ICLR: International Conference on Learning Representations.","chicago":"Lechner, Mathias. “Learning Representations for Binary-Classification without Backpropagation.” In <i>8th International Conference on Learning Representations</i>. ICLR, 2020.","short":"M. Lechner, in:, 8th International Conference on Learning Representations, ICLR, 2020."},"month":"03","_id":"10672","scopus_import":"1","corr_author":"1","year":"2020","conference":{"name":"ICLR: International Conference on Learning Representations","location":"Virtual ; Addis Ababa, Ethiopia","start_date":"2020-04-26","end_date":"2020-05-01"},"date_updated":"2025-04-15T06:25:56Z","file":[{"date_updated":"2022-01-26T07:35:17Z","file_size":249431,"content_type":"application/pdf","success":1,"date_created":"2022-01-26T07:35:17Z","file_name":"iclr_2020.pdf","creator":"mlechner","checksum":"ea13d42dd4541ddb239b6a75821fd6c9","relation":"main_file","file_id":"10677","access_level":"open_access"}]},{"scopus_import":"1","_id":"10673","publication_status":"published","citation":{"ama":"Hasani R, Lechner M, Amini A, Rus D, Grosu R. A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. In: <i>Proceedings of the 37th International Conference on Machine Learning</i>. PMLR. ; 2020:4082-4093.","ista":"Hasani R, Lechner M, Amini A, Rus D, Grosu R. 2020. A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. Proceedings of the 37th International Conference on Machine Learning. ML: Machine LearningPMLR, PMLR, , 4082–4093.","chicago":"Hasani, Ramin, Mathias Lechner, Alexander Amini, Daniela Rus, and Radu Grosu. “A Natural Lottery Ticket Winner: Reinforcement Learning with Ordinary Neural Circuits.” In <i>Proceedings of the 37th International Conference on Machine Learning</i>, 4082–93. PMLR, 2020.","short":"R. Hasani, M. Lechner, A. Amini, D. Rus, R. Grosu, in:, Proceedings of the 37th International Conference on Machine Learning, 2020, pp. 4082–4093.","ieee":"R. Hasani, M. Lechner, A. Amini, D. Rus, and R. Grosu, “A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits,” in <i>Proceedings of the 37th International Conference on Machine Learning</i>, Virtual, 2020, pp. 4082–4093.","mla":"Hasani, Ramin, et al. “A Natural Lottery Ticket Winner: Reinforcement Learning with Ordinary Neural Circuits.” <i>Proceedings of the 37th International Conference on Machine Learning</i>, 2020, pp. 4082–93.","apa":"Hasani, R., Lechner, M., Amini, A., Rus, D., &#38; Grosu, R. (2020). A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. In <i>Proceedings of the 37th International Conference on Machine Learning</i> (pp. 4082–4093). Virtual."},"type":"conference","publication":"Proceedings of the 37th International Conference on Machine Learning","department":[{"_id":"GradSch"},{"_id":"ToHe"}],"alternative_title":["PMLR"],"file":[{"date_updated":"2022-01-26T11:08:51Z","file_size":2329798,"content_type":"application/pdf","date_created":"2022-01-26T11:08:51Z","creator":"cchlebak","file_name":"2020_PMLR_Hasani.pdf","success":1,"access_level":"open_access","checksum":"c9a4a29161777fc1a89ef451c040e3b1","relation":"main_file","file_id":"10691"}],"page":"4082-4093","series_title":"PMLR","conference":{"end_date":"2020-07-18","name":"ML: Machine Learning","start_date":"2020-07-12","location":"Virtual"},"year":"2020","date_updated":"2025-04-15T06:25:56Z","abstract":[{"text":"We propose a neural information processing system obtained by re-purposing the function of a biological neural circuit model to govern simulated and real-world control tasks. Inspired by the structure of the nervous system of the soil-worm, C. elegans, we introduce ordinary neural circuits (ONCs), defined as the model of biological neural circuits reparameterized for the control of alternative tasks. We first demonstrate that ONCs realize networks with higher maximum flow compared to arbitrary wired networks. We then learn instances of ONCs to control a series of robotic tasks, including the autonomous parking of a real-world rover robot. For reconfiguration of the purpose of the neural circuit, we adopt a search-based optimization algorithm. Ordinary neural circuits perform on par and, in some cases, significantly surpass the performance of contemporary deep learning models. ONC networks are compact, 77% sparser than their counterpart neural controllers, and their neural dynamics are fully interpretable at the cell-level.","lang":"eng"}],"oa_version":"Published Version","project":[{"call_identifier":"FWF","_id":"25F42A32-B435-11E9-9278-68D0E5697425","grant_number":"Z211","name":"Formal methods for the design and analysis of complex systems"}],"quality_controlled":"1","status":"public","date_created":"2022-01-25T15:50:34Z","language":[{"iso":"eng"}],"oa":1,"file_date_updated":"2022-01-26T11:08:51Z","ddc":["000"],"date_published":"2020-01-01T00:00:00Z","main_file_link":[{"open_access":"1","url":"http://proceedings.mlr.press/v119/hasani20a.html"}],"author":[{"full_name":"Hasani, Ramin","first_name":"Ramin","last_name":"Hasani"},{"last_name":"Lechner","full_name":"Lechner, Mathias","id":"3DC22916-F248-11E8-B48F-1D18A9856A87","first_name":"Mathias"},{"first_name":"Alexander","full_name":"Amini, Alexander","last_name":"Amini"},{"first_name":"Daniela","full_name":"Rus, Daniela","last_name":"Rus"},{"first_name":"Radu","full_name":"Grosu, Radu","last_name":"Grosu"}],"acknowledgement":"RH and RG are partially supported by Horizon-2020 ECSEL Project grant No. 783163 (iDev40), Productive 4.0, and ATBMBFW CPS-IoT Ecosystem. ML was supported in part by the Austrian Science Fund (FWF) under grant Z211-N23\r\n(Wittgenstein Award). AA is supported by the National Science Foundation (NSF) Graduate Research Fellowship\r\nProgram. RH and DR are partially supported by The Boeing Company and JP Morgan Chase. This research work is\r\npartially drawn from the PhD dissertation of RH.\r\n","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","short":"CC BY-NC-ND (3.0)"},"publication_identifier":{"issn":["2640-3498"]},"article_processing_charge":"No","has_accepted_license":"1","title":"A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"issue":"1","year":"2020","conference":{"location":"Denver, CO, United States","start_date":"2020-03-02","name":"APS: American Physical Society","end_date":"2020-03-06"},"date_updated":"2022-01-27T10:58:38Z","intvolume":"        65","citation":{"ista":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. 2020. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B54. 00007.","ama":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Tanaguchi, Kenji Watanabe, and Andrea Young. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","ieee":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, and A. Young, “Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","apa":"Zhou, H., Polshyn, H., Tanaguchi, T., Watanabe, K., &#38; Young, A. (2020). Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Zhou, Haoxin, et al. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B54. 00007, American Physical Society, 2020."},"publication_status":"published","month":"03","_id":"10693","publisher":"American Physical Society","alternative_title":["Bulletin of the American Physical Society"],"day":"01","extern":"1","publication":"APS March Meeting 2020","type":"conference","article_number":"B54. 00007","volume":65,"article_processing_charge":"No","publication_identifier":{"issn":["0003-0503"]},"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order","status":"public","date_created":"2022-01-27T10:50:10Z","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"High quality graphene heterostructures host an array of fractional quantum Hall isospin ferromagnets with diverse spin and valley orders. While a variety of phase transitions have been observed, disentangling the isospin phase diagram of these states is hampered by the absence of direct probes of spin and valley order. I will describe nonlocal transport measurements based on launching spin waves from a gate defined lateral heterojunction, performed in ultra-clean Corbino geometry graphene devices. At high magnetic fields, we find that the spin-wave transport signal is detected in all FQH states between ν = 0 and 1; however, between ν = 1 and 2 only odd numerator FQH states show finite nonlocal transport, despite the identical ground state spin polarizations in odd- and even numerator states. The results reveal that the neutral spin-waves are both spin and sublattice polarized making them a sensitive probe of ground state sublattice structure. Armed with this understanding, we use nonlocal transport signal to a magnetic field tuned isospin phase transition, showing that the emergent even denominator state at ν = 1/2 in monolayer graphene is indeed a multicomponent state featuring equal populations on each sublattice."}],"quality_controlled":"1","oa_version":"Published Version","author":[{"full_name":"Zhou, Haoxin","first_name":"Haoxin","last_name":"Zhou"},{"id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"last_name":"Tanaguchi","first_name":"Takashi","full_name":"Tanaguchi, Takashi"},{"last_name":"Watanabe","first_name":"Kenji","full_name":"Watanabe, Kenji"},{"first_name":"Andrea","full_name":"Young, Andrea","last_name":"Young"}],"oa":1,"main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B54.7"}],"date_published":"2020-03-01T00:00:00Z"},{"_id":"10696","month":"03","intvolume":"        65","citation":{"short":"H. Polshyn, J. Zhu, M. Kumar, T. Taniguchi, K. Watanabe, A. MacDonald, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","chicago":"Polshyn, Hryhoriy, Jihang Zhu, Manish Kumar, Takashi Taniguchi, Kenji Watanabe, Allan MacDonald, and Andrea Young. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","ista":"Polshyn H, Zhu J, Kumar M, Taniguchi T, Watanabe K, MacDonald A, Young A. 2020. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B51.00005.","ama":"Polshyn H, Zhu J, Kumar M, et al. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Polshyn, H., Zhu, J., Kumar, M., Taniguchi, T., Watanabe, K., MacDonald, A., &#38; Young, A. (2020). Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Polshyn, Hryhoriy, et al. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B51.00005, American Physical Society, 2020.","ieee":"H. Polshyn <i>et al.</i>, “Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1."},"publication_status":"published","publication":"APS March Meeting 2020","type":"conference","day":"01","extern":"1","alternative_title":["Bulletin of the American Physical Society"],"publisher":"American Physical Society","issue":"1","date_updated":"2022-02-08T10:22:08Z","year":"2020","conference":{"end_date":"2020-03-06","location":"Denver, CO, United States","start_date":"2020-03-02","name":"APS: American Physical Society"},"quality_controlled":"1","oa_version":"Published Version","abstract":[{"text":"We experimentally investigate twisted van der Waals heterostructures of monolayer graphene rotated with respect to a bernal stacked graphene bilayer. We report transport measurements for devices with twist angles between 0.9 and 1.4°. The electric field allows efficient tuning of the width, isolation and the topology of the moiré bands in this system. By comparing magnetoresistance measurements to numerical simulations, we develop an understanding of the band structure. Finally, we observe correlated states at half- and quarter-fillings, which arise when narrow moire sublattice band is isolated by energy gaps from dispersive bands. We investigate the effects of in-plane and out-of-plane magnetic field on these states and discuss the implication for their spin- and valley- polarization.","lang":"eng"}],"language":[{"iso":"eng"}],"status":"public","date_created":"2022-01-28T10:09:19Z","main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B51.5","open_access":"1"}],"date_published":"2020-03-01T00:00:00Z","oa":1,"author":[{"last_name":"Polshyn","orcid":"0000-0001-8223-8896","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy","first_name":"Hryhoriy"},{"last_name":"Zhu","full_name":"Zhu, Jihang","first_name":"Jihang"},{"last_name":"Kumar","full_name":"Kumar, Manish","first_name":"Manish"},{"full_name":"Taniguchi, Takashi","first_name":"Takashi","last_name":"Taniguchi"},{"first_name":"Kenji","full_name":"Watanabe, Kenji","last_name":"Watanabe"},{"last_name":"MacDonald","first_name":"Allan","full_name":"MacDonald, Allan"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"publication_identifier":{"issn":["0003-0503"]},"volume":65,"article_processing_charge":"No","article_number":"B51.00005","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures"},{"conference":{"end_date":"2020-03-06","name":"APS: American Physical Society","start_date":"2020-03-02","location":"Denver, CO, United States"},"year":"2020","date_updated":"2023-02-21T15:57:52Z","external_id":{"arxiv":["1907.00261"]},"issue":"1","publisher":"American Physical Society","alternative_title":["Bulletin of the American Physical Society"],"day":"01","extern":"1","type":"conference","publication":"APS March Meeting 2020","publication_status":"published","citation":{"chicago":"Zhang, Yuxuan, Marec Serlin, Charles Tschirhart, Hryhoriy Polshyn, Jiacheng Zhu, Leon Balents, Martin E. Huber, Takashi Taniguchi, Kenji Watanabe, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"Y. Zhang, M. Serlin, C. Tschirhart, H. Polshyn, J. Zhu, L. Balents, M.E. Huber, T. Taniguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","ista":"Zhang Y, Serlin M, Tschirhart C, Polshyn H, Zhu J, Balents L, Huber ME, Taniguchi T, Watanabe K, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00012.","ama":"Zhang Y, Serlin M, Tschirhart C, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Zhang, Y., Serlin, M., Tschirhart, C., Polshyn, H., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Zhang, Yuxuan, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00012, American Physical Society, 2020.","ieee":"Y. Zhang <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1."},"intvolume":"        65","_id":"10697","arxiv":1,"month":"03","title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","article_number":"B59.00012","article_processing_charge":"No","volume":65,"acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work.","author":[{"first_name":"Yuxuan","full_name":"Zhang, Yuxuan","last_name":"Zhang"},{"last_name":"Serlin","full_name":"Serlin, Marec","first_name":"Marec"},{"first_name":"Charles","full_name":"Tschirhart, Charles","last_name":"Tschirhart"},{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"last_name":"Zhu","first_name":"Jiacheng","full_name":"Zhu, Jiacheng"},{"first_name":"Leon","full_name":"Balents, Leon","last_name":"Balents"},{"first_name":"Martin E.","full_name":"Huber, Martin E.","last_name":"Huber"},{"last_name":"Taniguchi","full_name":"Taniguchi, Takashi","first_name":"Takashi"},{"first_name":"Kenji","full_name":"Watanabe, Kenji","last_name":"Watanabe"},{"first_name":"Andrea","full_name":"Young, Andrea","last_name":"Young"}],"oa":1,"main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.12"}],"date_published":"2020-03-01T00:00:00Z","date_created":"2022-01-28T10:28:35Z","status":"public","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"We report the observation of a quantized anomalous Hall effect in a moiré heterostructure consisting of twisted bilayer graphene aligned to an encapsulating hBN substrate. The effect occurs at a density of 3 electrons per superlattice unit cell, where we observe magnetic hysteresis and a Hall resistance quantized to within 0.1% of the resistance quantum at temperatures as high as 3K. In this first of 3 talks, I will describe the fabrication procedure for our device as well as basic transport characterization measurements. I will introduce the phenomenology of twisted bilayer graphene and present evidence for hBN alignment as manifested in the hierarchy of symmetry-breaking gaps and anomalous magnetoresistance."}],"oa_version":"Published Version","related_material":{"record":[{"id":"10619","status":"public","relation":"other"}]},"quality_controlled":"1"},{"author":[{"first_name":"Marec","full_name":"Serlin, Marec","last_name":"Serlin"},{"last_name":"Tschirhart","full_name":"Tschirhart, Charles","first_name":"Charles"},{"orcid":"0000-0001-8223-8896","last_name":"Polshyn","first_name":"Hryhoriy","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"full_name":"Zhang, Yuxuan","first_name":"Yuxuan","last_name":"Zhang"},{"full_name":"Zhu, Jiacheng","first_name":"Jiacheng","last_name":"Zhu"},{"first_name":"Martin E.","full_name":"Huber, Martin E.","last_name":"Huber"},{"last_name":"Balents","first_name":"Leon","full_name":"Balents, Leon"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"first_name":"Takashi","full_name":"Tanaguchi, Takashi","last_name":"Tanaguchi"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.11","open_access":"1"}],"date_published":"2020-03-01T00:00:00Z","oa":1,"language":[{"iso":"eng"}],"date_created":"2022-01-28T10:46:57Z","status":"public","quality_controlled":"1","related_material":{"record":[{"relation":"other","id":"10619","status":"public"}]},"oa_version":"Published Version","abstract":[{"text":"This is the second of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. I will compare the qualitative and quantitative features of this observed quantum anomalous Hall state to traditional systems engineered from thin film (Bi,Sb)2Te3 topological insulators. In particular, we find that the measured electronic energy gap of ~30K is several times higher than the Curie temperature, consistent with a lack of disorder associated with magnetic dopants. In this system, the quantization arises from spontaneous ferromagnetic polarization into a single spin and valley moiré subband, which is topological despite the lack of spin orbit coupling. I will also discuss the observation of current induced switching, which allows the magnetic state of the heterostructure to be controllably reversed with currents as small as a few nanoamperes.","lang":"eng"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching","volume":65,"article_processing_charge":"No","article_number":"B59.00011","acknowledgement":"I would like to thank the MURI Program, AFOSR, Sloan Foundation, and the ARO for their generous support of this work.","alternative_title":["Bulletin of the American Physical Society"],"publisher":"American Physical Society","publication":"APS March Meeting 2020","type":"conference","extern":"1","day":"01","intvolume":"        65","publication_status":"published","citation":{"chicago":"Serlin, Marec, Charles Tschirhart, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Martin E. Huber, Leon Balents, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"M. Serlin, C. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, M.E. Huber, L. Balents, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","ama":"Serlin M, Tschirhart C, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Serlin M, Tschirhart C, Polshyn H, Zhang Y, Zhu J, Huber ME, Balents L, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00011.","mla":"Serlin, Marec, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00011, American Physical Society, 2020.","apa":"Serlin, M., Tschirhart, C., Polshyn, H., Zhang, Y., Zhu, J., Huber, M. E., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","ieee":"M. Serlin <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1."},"_id":"10698","arxiv":1,"month":"03","date_updated":"2023-02-21T15:57:52Z","external_id":{"arxiv":["1907.00261"]},"year":"2020","conference":{"end_date":"2020-03-06","name":"APS: American Physical Society","start_date":"2020-03-02","location":"Denver, CO, United States"},"issue":"1"},{"author":[{"full_name":"Tschirhart, Charles","first_name":"Charles","last_name":"Tschirhart"},{"last_name":"Serlin","first_name":"Marec","full_name":"Serlin, Marec"},{"first_name":"Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy","orcid":"0000-0001-8223-8896","last_name":"Polshyn"},{"first_name":"Yuxuan","full_name":"Zhang, Yuxuan","last_name":"Zhang"},{"last_name":"Zhu","full_name":"Zhu, Jiacheng","first_name":"Jiacheng"},{"last_name":"Balents","full_name":"Balents, Leon","first_name":"Leon"},{"last_name":"Huber","full_name":"Huber, Martin E.","first_name":"Martin E."},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"first_name":"Takashi","full_name":"Tanaguchi, Takashi","last_name":"Tanaguchi"},{"full_name":"Young, Andrea","first_name":"Andrea","last_name":"Young"}],"oa":1,"date_published":"2020-03-01T00:00:00Z","main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.13","open_access":"1"}],"status":"public","date_created":"2022-01-28T10:57:49Z","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"This is the third of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. In this segment I will present scanning probe magnetometry data acquired using a nanoSQUID-on-tip microscope, which provides ~150 nm spatial resolution and a field sensitivity of ~10 nT/rtHz. We study the distribution of magnetic domains within the device as a function of density, magnetic field training, and DC current. Our data allow us to constrain the magnitude of the orbital magnetic moment of the electrons in the QAH state. Comparison with simultaneously acquired transport data allows us to precisely correlate single domain dynamics with discrete jumps in the observed anomalous Hall signal."}],"oa_version":"Published Version","related_material":{"record":[{"status":"public","id":"10619","relation":"other"}]},"quality_controlled":"1","title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","article_number":"B59.00013","article_processing_charge":"No","volume":65,"acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work. I would also like to thank the NSF GRFP and the Hertz foundation for their generous support of my graduate studies.","publication_identifier":{"issn":["0003-0503"]},"publisher":"American Physical Society","alternative_title":["Bulletin of the American Physical Society"],"extern":"1","day":"01","type":"conference","publication":"APS March Meeting 2020","citation":{"mla":"Tschirhart, Charles, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00013, American Physical Society, 2020.","apa":"Tschirhart, C., Serlin, M., Polshyn, H., Zhang, Y., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","ieee":"C. Tschirhart <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","chicago":"Tschirhart, Charles, Marec Serlin, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Leon Balents, Martin E. Huber, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"C. Tschirhart, M. Serlin, H. Polshyn, Y. Zhang, J. Zhu, L. Balents, M.E. Huber, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","ama":"Tschirhart C, Serlin M, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Tschirhart C, Serlin M, Polshyn H, Zhang Y, Zhu J, Balents L, Huber ME, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00013."},"publication_status":"published","intvolume":"        65","_id":"10699","month":"03","arxiv":1,"conference":{"name":"APS: American Physical Society","start_date":"2020-03-02","location":"Denver, CO, United States","end_date":"2020-03-06"},"year":"2020","date_updated":"2023-02-21T15:57:52Z","external_id":{"arxiv":["1907.00261"]},"issue":"1"},{"intvolume":"        16","citation":{"ama":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. 2020;16(2):154-158. doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>","ista":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2020. Skyrmion solids in monolayer graphene. Nature Physics. 16(2), 154–158.","short":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics 16 (2020) 154–158.","chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Taniguchi, Kenji Watanabe, and Andrea F. Young. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>.","ieee":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Skyrmion solids in monolayer graphene,” <i>Nature Physics</i>, vol. 16, no. 2. Springer Nature, pp. 154–158, 2020.","mla":"Zhou, Haoxin, et al. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>, vol. 16, no. 2, Springer Nature, 2020, pp. 154–58, doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>.","apa":"Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., &#38; Young, A. F. (2020). Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>"},"publication_status":"published","month":"02","_id":"10701","arxiv":1,"publisher":"Springer Nature","publication":"Nature Physics","type":"journal_article","day":"01","extern":"1","issue":"2","page":"154-158","external_id":{"arxiv":["1904.11485"]},"date_updated":"2022-01-31T07:10:07Z","year":"2020","language":[{"iso":"eng"}],"doi":"10.1038/s41567-019-0729-8","status":"public","date_created":"2022-01-28T12:04:09Z","quality_controlled":"1","oa_version":"Preprint","abstract":[{"text":"Partially filled Landau levels host competing electronic orders. For example, electron solids may prevail close to integer filling of the Landau levels before giving way to fractional quantum Hall liquids at higher carrier density1,2. Here, we report the observation of an electron solid with non-collinear spin texture in monolayer graphene, consistent with solidification of skyrmions3—topological spin textures characterized by quantized electrical charge4,5. We probe the spin texture of the solids using a modified Corbino geometry that allows ferromagnetic magnons to be launched and detected6,7. We find that magnon transport is highly efficient when one Landau level is filled (ν=1), consistent with quantum Hall ferromagnetic spin polarization. However, even minimal doping immediately quenches the magnon signal while leaving the vanishing low-temperature charge conductivity unchanged. Our results can be understood by the formation of a solid of charged skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay. Data near fractional fillings show evidence of several fractional skyrmion solids, suggesting that graphene hosts a highly tunable landscape of coupled spin and charge orders.","lang":"eng"}],"author":[{"full_name":"Zhou, Haoxin","first_name":"Haoxin","last_name":"Zhou"},{"orcid":"0000-0001-8223-8896","last_name":"Polshyn","first_name":"Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy"},{"last_name":"Taniguchi","first_name":"Takashi","full_name":"Taniguchi, Takashi"},{"first_name":"Kenji","full_name":"Watanabe, Kenji","last_name":"Watanabe"},{"first_name":"Andrea F.","full_name":"Young, Andrea F.","last_name":"Young"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1904.11485"}],"date_published":"2020-02-01T00:00:00Z","oa":1,"volume":16,"article_processing_charge":"No","publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"acknowledgement":"We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST (JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard Foundation and and Alfred. P. Sloan Foundation.","article_type":"original","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Skyrmion solids in monolayer graphene"},{"publication_identifier":{"eissn":["1433-2787"],"issn":["1433-2779"]},"article_type":"original","isi":1,"volume":22,"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","title":"AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic","quality_controlled":"1","related_material":{"record":[{"relation":"earlier_version","id":"299","status":"public"}]},"oa_version":"None","abstract":[{"lang":"eng","text":"We introduce in this paper AMT2.0, a tool for qualitative and quantitative analysis of hybrid continuous and Boolean signals that combine numerical values and discrete events. The evaluation of the signals is based on rich temporal specifications expressed in extended signal temporal logic, which integrates timed regular expressions within signal temporal logic. The tool features qualitative monitoring (property satisfaction checking), trace diagnostics for explaining and justifying property violations and specification-driven measurement of quantitative features of the signal. We demonstrate the tool functionality on several running examples and case studies, and evaluate its performance."}],"language":[{"iso":"eng"}],"doi":"10.1007/s10009-020-00582-z","date_created":"2022-03-18T10:10:53Z","status":"public","date_published":"2020-08-03T00:00:00Z","author":[{"last_name":"Nickovic","first_name":"Dejan","full_name":"Nickovic, Dejan","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Lebeltel","first_name":"Olivier","full_name":"Lebeltel, Olivier"},{"last_name":"Maler","full_name":"Maler, Oded","first_name":"Oded"},{"first_name":"Thomas","full_name":"Ferrere, Thomas","id":"40960E6E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5199-3143","last_name":"Ferrere"},{"full_name":"Ulus, Dogan","first_name":"Dogan","last_name":"Ulus"}],"keyword":["Information Systems","Software"],"issue":"6","page":"741-758","external_id":{"isi":["000555398600001"]},"date_updated":"2024-10-09T20:58:18Z","year":"2020","month":"08","_id":"10861","scopus_import":"1","intvolume":"        22","citation":{"ama":"Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. <i>International Journal on Software Tools for Technology Transfer</i>. 2020;22(6):741-758. doi:<a href=\"https://doi.org/10.1007/s10009-020-00582-z\">10.1007/s10009-020-00582-z</a>","ista":"Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. 2020. AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. International Journal on Software Tools for Technology Transfer. 22(6), 741–758.","chicago":"Nickovic, Dejan, Olivier Lebeltel, Oded Maler, Thomas Ferrere, and Dogan Ulus. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s10009-020-00582-z\">https://doi.org/10.1007/s10009-020-00582-z</a>.","short":"D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, D. Ulus, International Journal on Software Tools for Technology Transfer 22 (2020) 741–758.","ieee":"D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, and D. Ulus, “AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic,” <i>International Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6. Springer Nature, pp. 741–758, 2020.","mla":"Nickovic, Dejan, et al. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6, Springer Nature, 2020, pp. 741–58, doi:<a href=\"https://doi.org/10.1007/s10009-020-00582-z\">10.1007/s10009-020-00582-z</a>.","apa":"Nickovic, D., Lebeltel, O., Maler, O., Ferrere, T., &#38; Ulus, D. (2020). AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10009-020-00582-z\">https://doi.org/10.1007/s10009-020-00582-z</a>"},"publication_status":"published","publication":"International Journal on Software Tools for Technology Transfer","type":"journal_article","day":"03","department":[{"_id":"ToHe"}],"publisher":"Springer Nature"},{"date_updated":"2025-04-15T08:05:01Z","external_id":{"arxiv":["1708.01597"],"isi":["000559623200009"]},"year":"2020","issue":"7","ec_funded":1,"department":[{"_id":"LaEr"}],"publisher":"Elsevier","publication":"Journal of Functional Analysis","type":"journal_article","day":"15","intvolume":"       279","publication_status":"published","citation":{"ista":"Bao Z, Erdös L, Schnelli K. 2020. Spectral rigidity for addition of random matrices at the regular edge. Journal of Functional Analysis. 279(7), 108639.","ama":"Bao Z, Erdös L, Schnelli K. Spectral rigidity for addition of random matrices at the regular edge. <i>Journal of Functional Analysis</i>. 2020;279(7). doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">10.1016/j.jfa.2020.108639</a>","short":"Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 279 (2020).","chicago":"Bao, Zhigang, László Erdös, and Kevin Schnelli. “Spectral Rigidity for Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">https://doi.org/10.1016/j.jfa.2020.108639</a>.","ieee":"Z. Bao, L. Erdös, and K. Schnelli, “Spectral rigidity for addition of random matrices at the regular edge,” <i>Journal of Functional Analysis</i>, vol. 279, no. 7. Elsevier, 2020.","apa":"Bao, Z., Erdös, L., &#38; Schnelli, K. (2020). Spectral rigidity for addition of random matrices at the regular edge. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">https://doi.org/10.1016/j.jfa.2020.108639</a>","mla":"Bao, Zhigang, et al. “Spectral Rigidity for Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>, vol. 279, no. 7, 108639, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">10.1016/j.jfa.2020.108639</a>."},"corr_author":"1","arxiv":1,"_id":"10862","month":"10","scopus_import":"1","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","title":"Spectral rigidity for addition of random matrices at the regular edge","volume":279,"article_processing_charge":"No","article_number":"108639","publication_identifier":{"issn":["0022-1236"]},"isi":1,"article_type":"original","acknowledgement":"Partially supported by ERC Advanced Grant RANMAT No. 338804.","author":[{"full_name":"Bao, Zhigang","id":"442E6A6C-F248-11E8-B48F-1D18A9856A87","first_name":"Zhigang","last_name":"Bao","orcid":"0000-0003-3036-1475"},{"first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","full_name":"Erdös, László","orcid":"0000-0001-5366-9603","last_name":"Erdös"},{"first_name":"Kevin","full_name":"Schnelli, Kevin","last_name":"Schnelli"}],"keyword":["Analysis"],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1708.01597"}],"date_published":"2020-10-15T00:00:00Z","oa":1,"language":[{"iso":"eng"}],"doi":"10.1016/j.jfa.2020.108639","date_created":"2022-03-18T10:18:59Z","status":"public","project":[{"call_identifier":"FP7","_id":"258DCDE6-B435-11E9-9278-68D0E5697425","grant_number":"338804","name":"Random matrices, universality and disordered quantum systems"}],"quality_controlled":"1","oa_version":"Preprint","abstract":[{"lang":"eng","text":"We consider the sum of two large Hermitian matrices A and B with a Haar unitary conjugation bringing them into a general relative position. We prove that the eigenvalue density on the scale slightly above the local eigenvalue spacing is asymptotically given by the free additive convolution of the laws of A and B as the dimension of the matrix increases. This implies optimal rigidity of the eigenvalues and optimal rate of convergence in Voiculescu's theorem. Our previous works [4], [5] established these results in the bulk spectrum, the current paper completely settles the problem at the spectral edges provided they have the typical square-root behavior. The key element of our proof is to compensate the deterioration of the stability of the subordination equations by sharp error estimates that properly account for the local density near the edge. Our results also hold if the Haar unitary matrix is replaced by the Haar orthogonal matrix."}]},{"publisher":"Springer Nature","publication":"Public-Key Cryptography","type":"book_chapter","day":"29","intvolume":"     12110","citation":{"ista":"Chakraborty S, Prabhakaran M, Wichs D. 2020.Witness maps and applications. In: Public-Key Cryptography. vol. 12110, 220–246.","ama":"Chakraborty S, Prabhakaran M, Wichs D. Witness maps and applications. In: Kiayias A, ed. <i>Public-Key Cryptography</i>. Vol 12110. LNCS. Cham: Springer Nature; 2020:220-246. doi:<a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">10.1007/978-3-030-45374-9_8</a>","chicago":"Chakraborty, Suvradip, Manoj Prabhakaran, and Daniel Wichs. “Witness Maps and Applications.” In <i>Public-Key Cryptography</i>, edited by A Kiayias, 12110:220–46. LNCS. Cham: Springer Nature, 2020. <a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">https://doi.org/10.1007/978-3-030-45374-9_8</a>.","short":"S. Chakraborty, M. Prabhakaran, D. Wichs, in:, A. Kiayias (Ed.), Public-Key Cryptography, Springer Nature, Cham, 2020, pp. 220–246.","ieee":"S. Chakraborty, M. Prabhakaran, and D. Wichs, “Witness maps and applications,” in <i>Public-Key Cryptography</i>, vol. 12110, A. Kiayias, Ed. Cham: Springer Nature, 2020, pp. 220–246.","apa":"Chakraborty, S., Prabhakaran, M., &#38; Wichs, D. (2020). Witness maps and applications. In A. Kiayias (Ed.), <i>Public-Key Cryptography</i> (Vol. 12110, pp. 220–246). Cham: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">https://doi.org/10.1007/978-3-030-45374-9_8</a>","mla":"Chakraborty, Suvradip, et al. “Witness Maps and Applications.” <i>Public-Key Cryptography</i>, edited by A Kiayias, vol. 12110, Springer Nature, 2020, pp. 220–46, doi:<a href=\"https://doi.org/10.1007/978-3-030-45374-9_8\">10.1007/978-3-030-45374-9_8</a>."},"publication_status":"published","corr_author":"1","_id":"10865","month":"04","scopus_import":"1","external_id":{"isi":["001299210200008"]},"date_updated":"2025-09-10T10:31:24Z","year":"2020","place":"Cham","series_title":"LNCS","page":"220-246","author":[{"full_name":"Chakraborty, Suvradip","id":"B9CD0494-D033-11E9-B219-A439E6697425","first_name":"Suvradip","last_name":"Chakraborty"},{"first_name":"Manoj","full_name":"Prabhakaran, Manoj","last_name":"Prabhakaran"},{"last_name":"Wichs","full_name":"Wichs, Daniel","first_name":"Daniel"}],"main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2020/090"}],"date_published":"2020-04-29T00:00:00Z","oa":1,"language":[{"iso":"eng"}],"doi":"10.1007/978-3-030-45374-9_8","date_created":"2022-03-18T11:35:51Z","status":"public","quality_controlled":"1","oa_version":"Preprint","abstract":[{"text":"We introduce the notion of Witness Maps as a cryptographic notion of a proof system. A Unique Witness Map (UWM) deterministically maps all witnesses for an   NP  statement to a single representative witness, resulting in a computationally sound, deterministic-prover, non-interactive witness independent proof system. A relaxation of UWM, called Compact Witness Map (CWM), maps all the witnesses to a small number of witnesses, resulting in a “lossy” deterministic-prover, non-interactive proof-system. We also define a Dual Mode Witness Map (DMWM) which adds an “extractable” mode to a CWM.\r\nOur main construction is a DMWM for all   NP  relations, assuming sub-exponentially secure indistinguishability obfuscation (  iO ), along with standard cryptographic assumptions. The DMWM construction relies on a CWM and a new primitive called Cumulative All-Lossy-But-One Trapdoor Functions (C-ALBO-TDF), both of which are in turn instantiated based on   iO  and other primitives. Our instantiation of a CWM is in fact a UWM; in turn, we show that a UWM implies Witness Encryption. Along the way to constructing UWM and C-ALBO-TDF, we also construct, from standard assumptions, Puncturable Digital Signatures and a new primitive called Cumulative Lossy Trapdoor Functions (C-LTDF). The former improves up on a construction of Bellare et al. (Eurocrypt 2016), who relied on sub-exponentially secure   iO  and sub-exponentially secure OWF.\r\nAs an application of our constructions, we show how to use a DMWM to construct the first leakage and tamper-resilient signatures with a deterministic signer, thereby solving a decade old open problem posed by Katz and Vaikunthanathan (Asiacrypt 2009), by Boyle, Segev and Wichs (Eurocrypt 2011), as well as by Faonio and Venturi (Asiacrypt 2016). Our construction achieves the optimal leakage rate of   1−o(1) .","lang":"eng"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","editor":[{"first_name":"A","full_name":"Kiayias, A","last_name":"Kiayias"}],"title":"Witness maps and applications","volume":12110,"article_processing_charge":"No","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783030453732","9783030453749"]},"isi":1,"acknowledgement":"We would like to thank the anonymous reviewers of PKC 2019 for their useful comments and suggestions. We thank Omer Paneth for pointing out to us the connection between Unique Witness Maps (UWM) and Witness encryption (WE). The first author would like to acknowledge Pandu Rangan for his involvement during the initial discussion phase of the project."},{"scopus_import":"1","_id":"10866","month":"07","arxiv":1,"citation":{"ieee":"J. Duan <i>et al.</i>, “Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs,” <i>Nano Letters</i>, vol. 20, no. 7. American Chemical Society, pp. 5323–5329, 2020.","mla":"Duan, Jiahua, et al. “Twisted Nano-Optics: Manipulating Light at the Nanoscale with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>, vol. 20, no. 7, American Chemical Society, 2020, pp. 5323–29, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">10.1021/acs.nanolett.0c01673</a>.","apa":"Duan, J., Capote-Robayna, N., Taboada-Gutiérrez, J., Álvarez-Pérez, G., Prieto Gonzalez, I., Martín-Sánchez, J., … Alonso-González, P. (2020). Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">https://doi.org/10.1021/acs.nanolett.0c01673</a>","ama":"Duan J, Capote-Robayna N, Taboada-Gutiérrez J, et al. Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano Letters</i>. 2020;20(7):5323-5329. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">10.1021/acs.nanolett.0c01673</a>","ista":"Duan J, Capote-Robayna N, Taboada-Gutiérrez J, Álvarez-Pérez G, Prieto Gonzalez I, Martín-Sánchez J, Nikitin AY, Alonso-González P. 2020. Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano Letters. 20(7), 5323–5329.","short":"J. Duan, N. Capote-Robayna, J. Taboada-Gutiérrez, G. Álvarez-Pérez, I. Prieto Gonzalez, J. Martín-Sánchez, A.Y. Nikitin, P. Alonso-González, Nano Letters 20 (2020) 5323–5329.","chicago":"Duan, Jiahua, Nathaniel Capote-Robayna, Javier Taboada-Gutiérrez, Gonzalo Álvarez-Pérez, Ivan Prieto Gonzalez, Javier Martín-Sánchez, Alexey Y. Nikitin, and Pablo Alonso-González. “Twisted Nano-Optics: Manipulating Light at the Nanoscale with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>. American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/acs.nanolett.0c01673\">https://doi.org/10.1021/acs.nanolett.0c01673</a>."},"publication_status":"published","intvolume":"        20","type":"journal_article","publication":"Nano Letters","day":"01","publisher":"American Chemical Society","department":[{"_id":"NanoFab"}],"issue":"7","page":"5323-5329","external_id":{"pmid":["32530634"],"arxiv":["2004.14599"],"isi":["000548893200082"]},"date_updated":"2023-09-05T12:05:58Z","year":"2020","oa_version":"Preprint","quality_controlled":"1","abstract":[{"text":"Recent discoveries have shown that, when two layers of van der Waals (vdW) materials are superimposed with a relative twist angle between them, the electronic properties of the coupled system can be dramatically altered. Here, we demonstrate that a similar concept can be extended to the optics realm, particularly to propagating phonon polaritons–hybrid light-matter interactions. To do this, we fabricate stacks composed of two twisted slabs of a vdW crystal (α-MoO3) supporting anisotropic phonon polaritons (PhPs), and image the propagation of the latter when launched by localized sources. Our images reveal that, under a critical angle, the PhPs isofrequency curve undergoes a topological transition, in which the propagation of PhPs is strongly guided (canalization regime) along predetermined directions without geometric spreading. These results demonstrate a new degree of freedom (twist angle) for controlling the propagation of polaritons at the nanoscale with potential for nanoimaging, (bio)-sensing, or heat management.","lang":"eng"}],"doi":"10.1021/acs.nanolett.0c01673","language":[{"iso":"eng"}],"status":"public","date_created":"2022-03-18T11:37:38Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2004.14599"}],"date_published":"2020-07-01T00:00:00Z","oa":1,"author":[{"full_name":"Duan, Jiahua","first_name":"Jiahua","last_name":"Duan"},{"full_name":"Capote-Robayna, Nathaniel","first_name":"Nathaniel","last_name":"Capote-Robayna"},{"last_name":"Taboada-Gutiérrez","full_name":"Taboada-Gutiérrez, Javier","first_name":"Javier"},{"last_name":"Álvarez-Pérez","full_name":"Álvarez-Pérez, Gonzalo","first_name":"Gonzalo"},{"last_name":"Prieto Gonzalez","orcid":"0000-0002-7370-5357","id":"2A307FE2-F248-11E8-B48F-1D18A9856A87","full_name":"Prieto Gonzalez, Ivan","first_name":"Ivan"},{"last_name":"Martín-Sánchez","full_name":"Martín-Sánchez, Javier","first_name":"Javier"},{"last_name":"Nikitin","first_name":"Alexey Y.","full_name":"Nikitin, Alexey Y."},{"first_name":"Pablo","full_name":"Alonso-González, Pablo","last_name":"Alonso-González"}],"keyword":["Mechanical Engineering","Condensed Matter Physics","General Materials Science","General Chemistry","Bioengineering"],"publication_identifier":{"eissn":["1530-6992"],"issn":["1530-6984"]},"acknowledgement":"J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa Program from the\r\nGovernment of the Principality of Asturias (nos. PA-18-PF-BP17-126 and PA20-PF-BP19-053,\r\nrespectively). J. M-S acknowledges financial support through the Ramón y Cajal Program from\r\nthe Government of Spain (RYC2018-026196-I). A.Y.N. acknowledges the Spanish Ministry of\r\nScience, Innovation and Universities (national project no. MAT201788358-C3-3-R). P.A.-G.\r\nacknowledges support from the European Research Council under starting grant no. 715496,\r\n2DNANOPTICA.","isi":1,"article_type":"original","pmid":1,"article_processing_charge":"No","volume":20,"title":"Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon polaritonic slabs","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1"},{"abstract":[{"text":"In this paper we find a tight estimate for Gromov’s waist of the balls in spaces of constant curvature, deduce the estimates for the balls in Riemannian manifolds with upper bounds on the curvature (CAT(ϰ)-spaces), and establish similar result for normed spaces.","lang":"eng"}],"oa_version":"Preprint","quality_controlled":"1","date_created":"2022-03-18T11:39:30Z","status":"public","doi":"10.1093/imrn/rny037","language":[{"iso":"eng"}],"oa":1,"main_file_link":[{"url":"https://arxiv.org/abs/1702.07513","open_access":"1"}],"date_published":"2020-02-01T00:00:00Z","keyword":["General Mathematics"],"author":[{"first_name":"Arseniy","id":"430D2C90-F248-11E8-B48F-1D18A9856A87","full_name":"Akopyan, Arseniy","orcid":"0000-0002-2548-617X","last_name":"Akopyan"},{"first_name":"Roman","full_name":"Karasev, Roman","last_name":"Karasev"}],"article_type":"original","acknowledgement":" Supported by the Russian Foundation for Basic Research grant 18-01-00036.","isi":1,"publication_identifier":{"eissn":["1687-0247"],"issn":["1073-7928"]},"article_processing_charge":"No","volume":2020,"title":"Waist of balls in hyperbolic and spherical spaces","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","scopus_import":"1","_id":"10867","month":"02","arxiv":1,"publication_status":"published","citation":{"mla":"Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical Spaces.” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3, Oxford University Press, 2020, pp. 669–97, doi:<a href=\"https://doi.org/10.1093/imrn/rny037\">10.1093/imrn/rny037</a>.","apa":"Akopyan, A., &#38; Karasev, R. (2020). Waist of balls in hyperbolic and spherical spaces. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rny037\">https://doi.org/10.1093/imrn/rny037</a>","ieee":"A. Akopyan and R. Karasev, “Waist of balls in hyperbolic and spherical spaces,” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3. Oxford University Press, pp. 669–697, 2020.","short":"A. Akopyan, R. Karasev, International Mathematics Research Notices 2020 (2020) 669–697.","chicago":"Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical Spaces.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/imrn/rny037\">https://doi.org/10.1093/imrn/rny037</a>.","ama":"Akopyan A, Karasev R. Waist of balls in hyperbolic and spherical spaces. <i>International Mathematics Research Notices</i>. 2020;2020(3):669-697. doi:<a href=\"https://doi.org/10.1093/imrn/rny037\">10.1093/imrn/rny037</a>","ista":"Akopyan A, Karasev R. 2020. Waist of balls in hyperbolic and spherical spaces. International Mathematics Research Notices. 2020(3), 669–697."},"intvolume":"      2020","day":"01","type":"journal_article","publication":"International Mathematics Research Notices","publisher":"Oxford University Press","department":[{"_id":"HeEd"}],"page":"669-697","issue":"3","year":"2020","external_id":{"isi":["000522852700002"],"arxiv":["1702.07513"]},"date_updated":"2023-08-24T14:19:55Z"},{"article_type":"review","publication_identifier":{"issn":["0896-6273"]},"pmid":1,"article_processing_charge":"No","volume":106,"title":"Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"In recent years, the nuclear pore complex (NPC) has emerged as a key player in genome regulation and cellular homeostasis. New discoveries have revealed that the NPC has multiple cellular functions besides mediating the molecular exchange between the nucleus and the cytoplasm. In this review, we discuss non-transport aspects of the NPC focusing on the NPC-genome interaction, the extreme longevity of the NPC proteins, and NPC dysfunction in age-related diseases. The examples summarized herein demonstrate that the NPC, which first evolved to enable the biochemical communication between the nucleus and the cytoplasm, now doubles as the gatekeeper of cellular identity and aging.","lang":"eng"}],"oa_version":"Published Version","quality_controlled":"1","date_created":"2022-04-07T07:43:36Z","status":"public","doi":"10.1016/j.neuron.2020.05.031","language":[{"iso":"eng"}],"oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.neuron.2020.05.031"}],"date_published":"2020-06-17T00:00:00Z","keyword":["General Neuroscience"],"author":[{"full_name":"Cho, Ukrae H.","first_name":"Ukrae H.","last_name":"Cho"},{"last_name":"HETZER","orcid":"0000-0002-2111-992X","full_name":"HETZER, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","first_name":"Martin W"}],"page":"899-911","issue":"6","year":"2020","external_id":{"pmid":["32553207"]},"date_updated":"2024-10-14T11:15:26Z","scopus_import":"1","_id":"11054","month":"06","publication_status":"published","citation":{"ieee":"U. H. Cho and M. Hetzer, “Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging,” <i>Neuron</i>, vol. 106, no. 6. Elsevier, pp. 899–911, 2020.","apa":"Cho, U. H., &#38; Hetzer, M. (2020). Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2020.05.031\">https://doi.org/10.1016/j.neuron.2020.05.031</a>","mla":"Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging.” <i>Neuron</i>, vol. 106, no. 6, Elsevier, 2020, pp. 899–911, doi:<a href=\"https://doi.org/10.1016/j.neuron.2020.05.031\">10.1016/j.neuron.2020.05.031</a>.","ista":"Cho UH, Hetzer M. 2020. Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. Neuron. 106(6), 899–911.","ama":"Cho UH, Hetzer M. Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. <i>Neuron</i>. 2020;106(6):899-911. doi:<a href=\"https://doi.org/10.1016/j.neuron.2020.05.031\">10.1016/j.neuron.2020.05.031</a>","chicago":"Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging.” <i>Neuron</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.neuron.2020.05.031\">https://doi.org/10.1016/j.neuron.2020.05.031</a>.","short":"U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911."},"intvolume":"       106","extern":"1","day":"17","type":"journal_article","publication":"Neuron","publisher":"Elsevier"},{"date_updated":"2024-10-14T11:17:02Z","external_id":{"pmid":["32896271"]},"year":"2020","file":[{"success":1,"date_created":"2022-04-08T06:53:10Z","creator":"dernst","file_name":"2020_eLife_Bersini.pdf","checksum":"f8b3821349a194050be02570d8fe7d4b","relation":"main_file","file_id":"11132","access_level":"open_access","date_updated":"2022-04-08T06:53:10Z","file_size":4399825,"content_type":"application/pdf"}],"type":"journal_article","publication":"eLife","extern":"1","day":"08","publisher":"eLife Sciences Publications","scopus_import":"1","month":"09","_id":"11055","citation":{"short":"S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020).","chicago":"Bersini, Simone, Roberta Schulte, Ling Huang, Hannah Tsai, and Martin Hetzer. “Direct Reprogramming of Human Smooth Muscle and Vascular Endothelial Cells Reveals Defects Associated with Aging and Hutchinson-Gilford Progeria Syndrome.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/elife.54383\">https://doi.org/10.7554/elife.54383</a>.","ama":"Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/elife.54383\">10.7554/elife.54383</a>","ista":"Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. 2020. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. eLife. 9, e54383.","mla":"Bersini, Simone, et al. “Direct Reprogramming of Human Smooth Muscle and Vascular Endothelial Cells Reveals Defects Associated with Aging and Hutchinson-Gilford Progeria Syndrome.” <i>ELife</i>, vol. 9, e54383, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/elife.54383\">10.7554/elife.54383</a>.","apa":"Bersini, S., Schulte, R., Huang, L., Tsai, H., &#38; Hetzer, M. (2020). Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.54383\">https://doi.org/10.7554/elife.54383</a>","ieee":"S. Bersini, R. Schulte, L. Huang, H. Tsai, and M. Hetzer, “Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020."},"publication_status":"published","intvolume":"         9","title":"Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2050-084X"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"article_type":"original","article_processing_charge":"No","pmid":1,"has_accepted_license":"1","volume":9,"article_number":"e54383","date_published":"2020-09-08T00:00:00Z","file_date_updated":"2022-04-08T06:53:10Z","oa":1,"ddc":["570"],"author":[{"last_name":"Bersini","first_name":"Simone","full_name":"Bersini, Simone"},{"first_name":"Roberta","full_name":"Schulte, Roberta","last_name":"Schulte"},{"last_name":"Huang","full_name":"Huang, Ling","first_name":"Ling"},{"first_name":"Hannah","full_name":"Tsai, Hannah","last_name":"Tsai"},{"first_name":"Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","last_name":"HETZER"}],"keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Medicine","General Neuroscience"],"oa_version":"Published Version","quality_controlled":"1","abstract":[{"text":"Vascular dysfunctions are a common feature of multiple age-related diseases. However, modeling healthy and pathological aging of the human vasculature represents an unresolved experimental challenge. Here, we generated induced vascular endothelial cells (iVECs) and smooth muscle cells (iSMCs) by direct reprogramming of healthy human fibroblasts from donors of different ages and Hutchinson-Gilford Progeria Syndrome (HGPS) patients. iVECs induced from old donors revealed upregulation of GSTM1 and PALD1, genes linked to oxidative stress, inflammation and endothelial junction stability, as vascular aging markers. A functional assay performed on PALD1 KD VECs demonstrated a recovery in vascular permeability. We found that iSMCs from HGPS donors overexpressed bone morphogenetic protein (BMP)−4, which plays a key role in both vascular calcification and endothelial barrier damage observed in HGPS. Strikingly, BMP4 concentrations are higher in serum from HGPS vs. age-matched mice. Furthermore, targeting BMP4 with blocking antibody recovered the functionality of the vascular barrier in vitro, hence representing a potential future therapeutic strategy to limit cardiovascular dysfunction in HGPS. These results show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro.","lang":"eng"}],"doi":"10.7554/elife.54383","language":[{"iso":"eng"}],"date_created":"2022-04-07T07:43:48Z","status":"public"},{"external_id":{"pmid":["32402127"]},"date_updated":"2024-10-14T11:18:07Z","year":"2020","issue":"5","file":[{"date_updated":"2022-04-08T07:06:05Z","file_size":2490829,"content_type":"application/pdf","date_created":"2022-04-08T07:06:05Z","file_name":"2020_AdvancedBiosystems_Bersini.pdf","creator":"dernst","success":1,"access_level":"open_access","checksum":"5584d9a1609812dc75c02ce1e35d2ec0","relation":"main_file","file_id":"11134"}],"publisher":"Wiley","publication":"Advanced Biosystems","type":"journal_article","extern":"1","day":"01","intvolume":"         4","publication_status":"published","citation":{"mla":"Bersini, Simone, et al. “Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.” <i>Advanced Biosystems</i>, vol. 4, no. 5, 2000044, Wiley, 2020, doi:<a href=\"https://doi.org/10.1002/adbi.202000044\">10.1002/adbi.202000044</a>.","apa":"Bersini, S., Arrojo e Drigo, R., Huang, L., Shokhirev, M. N., &#38; Hetzer, M. (2020). Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. <i>Advanced Biosystems</i>. Wiley. <a href=\"https://doi.org/10.1002/adbi.202000044\">https://doi.org/10.1002/adbi.202000044</a>","ieee":"S. Bersini, R. Arrojo e Drigo, L. Huang, M. N. Shokhirev, and M. Hetzer, “Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease,” <i>Advanced Biosystems</i>, vol. 4, no. 5. Wiley, 2020.","short":"S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced Biosystems 4 (2020).","chicago":"Bersini, Simone, Rafael Arrojo e Drigo, Ling Huang, Maxim N. Shokhirev, and Martin Hetzer. “Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.” <i>Advanced Biosystems</i>. Wiley, 2020. <a href=\"https://doi.org/10.1002/adbi.202000044\">https://doi.org/10.1002/adbi.202000044</a>.","ama":"Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. <i>Advanced Biosystems</i>. 2020;4(5). doi:<a href=\"https://doi.org/10.1002/adbi.202000044\">10.1002/adbi.202000044</a>","ista":"Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. 2020. Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. Advanced Biosystems. 4(5), 2000044."},"_id":"11056","month":"05","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease","volume":4,"pmid":1,"article_processing_charge":"No","has_accepted_license":"1","article_number":"2000044","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"publication_identifier":{"issn":["2366-7478","2366-7478"]},"article_type":"original","author":[{"last_name":"Bersini","first_name":"Simone","full_name":"Bersini, Simone"},{"last_name":"Arrojo e Drigo","first_name":"Rafael","full_name":"Arrojo e Drigo, Rafael"},{"last_name":"Huang","first_name":"Ling","full_name":"Huang, Ling"},{"first_name":"Maxim N.","full_name":"Shokhirev, Maxim N.","last_name":"Shokhirev"},{"first_name":"Martin W","full_name":"HETZER, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","last_name":"HETZER"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","Biomedical Engineering","Biomaterials"],"date_published":"2020-05-01T00:00:00Z","ddc":["570"],"oa":1,"file_date_updated":"2022-04-08T07:06:05Z","language":[{"iso":"eng"}],"doi":"10.1002/adbi.202000044","date_created":"2022-04-07T07:43:57Z","status":"public","quality_controlled":"1","oa_version":"Published Version","abstract":[{"text":"Aging of the circulatory system correlates with the pathogenesis of a large spectrum of diseases. However, it is largely unknown which factors drive the age-dependent or pathological decline of the vasculature and how vascular defects relate to tissue aging. The goal of the study is to design a multianalytical approach to identify how the cellular microenvironment (i.e., fibroblasts) and serum from healthy donors of different ages or Alzheimer disease (AD) patients can modulate the functionality of organ-specific vascular endothelial cells (VECs). Long-living human microvascular networks embedding VECs and fibroblasts from skin biopsies are generated. RNA-seq, secretome analyses, and microfluidic assays demonstrate that fibroblasts from young donors restore the functionality of aged endothelial cells, an effect also achieved by serum from young donors. New biomarkers of vascular aging are validated in human biopsies and it is shown that young serum induces angiopoietin-like-4, which can restore compromised vascular barriers. This strategy is then employed to characterize transcriptional/functional changes induced on the blood–brain barrier by AD serum, demonstrating the importance of PTP4A3 in the regulation of permeability. Features of vascular degeneration during aging and AD are recapitulated, and a tool to identify novel biomarkers that can be exploited to develop future therapeutics modulating vascular function is established.","lang":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation","volume":34,"pmid":1,"has_accepted_license":"1","article_processing_charge":"No","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"publication_identifier":{"issn":["0890-9369","1549-5477"]},"article_type":"original","author":[{"last_name":"Kang","full_name":"Kang, Hyeseon","first_name":"Hyeseon"},{"first_name":"Maxim N.","full_name":"Shokhirev, Maxim N.","last_name":"Shokhirev"},{"first_name":"Zhichao","full_name":"Xu, Zhichao","last_name":"Xu"},{"first_name":"Sahaana","full_name":"Chandran, Sahaana","last_name":"Chandran"},{"full_name":"Dixon, Jesse R.","first_name":"Jesse R.","last_name":"Dixon"},{"first_name":"Martin W","full_name":"HETZER, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","last_name":"HETZER"}],"keyword":["Developmental Biology","Genetics"],"date_published":"2020-04-28T00:00:00Z","ddc":["570"],"oa":1,"file_date_updated":"2022-04-08T07:12:33Z","language":[{"iso":"eng"}],"doi":"10.1101/gad.335794.119","date_created":"2022-04-07T07:44:09Z","status":"public","quality_controlled":"1","oa_version":"Published Version","abstract":[{"text":"During mitosis, transcription of genomic DNA is dramatically reduced, before it is reactivated during nuclear reformation in anaphase/telophase. Many aspects of the underlying principles that mediate transcriptional memory and reactivation in the daughter cells remain unclear. Here, we used ChIP-seq on synchronized cells at different stages after mitosis to generate genome-wide maps of histone modifications. Combined with EU-RNA-seq and Hi-C analyses, we found that during prometaphase, promoters, enhancers, and insulators retain H3K4me3 and H3K4me1, while losing H3K27ac. Enhancers globally retaining mitotic H3K4me1 or locally retaining mitotic H3K27ac are associated with cell type-specific genes and their transcription factors for rapid transcriptional activation. As cells exit mitosis, promoters regain H3K27ac, which correlates with transcriptional reactivation. Insulators also gain H3K27ac and CCCTC-binding factor (CTCF) in anaphase/telophase. This increase of H3K27ac in anaphase/telophase is required for posttranscriptional activation and may play a role in the establishment of topologically associating domains (TADs). Together, our results suggest that the genome is reorganized in a sequential order, in which histone methylations occur first in prometaphase, histone acetylation, and CTCF in anaphase/telophase, transcription in cytokinesis, and long-range chromatin interactions in early G1. We thus provide insights into the histone modification landscape that allows faithful reestablishment of the transcriptional program and TADs during cell division.","lang":"eng"}],"date_updated":"2024-10-14T11:18:25Z","external_id":{"pmid":["32499403"]},"year":"2020","issue":"13-14","file":[{"access_level":"open_access","checksum":"84e92d40e67936c739628315c238daf9","file_id":"11136","relation":"main_file","date_created":"2022-04-08T07:12:33Z","file_name":"2020_GenesDevelopment_Kang.pdf","creator":"dernst","success":1,"content_type":"application/pdf","date_updated":"2022-04-08T07:12:33Z","file_size":4406772}],"page":"913-930","publisher":"Cold Spring Harbor Laboratory Press","publication":"Genes & Development","type":"journal_article","day":"28","extern":"1","intvolume":"        34","publication_status":"published","citation":{"short":"H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes &#38; Development 34 (2020) 913–930.","chicago":"Kang, Hyeseon, Maxim N. Shokhirev, Zhichao Xu, Sahaana Chandran, Jesse R. Dixon, and Martin Hetzer. “Dynamic Regulation of Histone Modifications and Long-Range Chromosomal Interactions during Postmitotic Transcriptional Reactivation.” <i>Genes &#38; Development</i>. Cold Spring Harbor Laboratory Press, 2020. <a href=\"https://doi.org/10.1101/gad.335794.119\">https://doi.org/10.1101/gad.335794.119</a>.","ama":"Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. <i>Genes &#38; Development</i>. 2020;34(13-14):913-930. doi:<a href=\"https://doi.org/10.1101/gad.335794.119\">10.1101/gad.335794.119</a>","ista":"Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. 2020. Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. Genes &#38; Development. 34(13–14), 913–930.","mla":"Kang, Hyeseon, et al. “Dynamic Regulation of Histone Modifications and Long-Range Chromosomal Interactions during Postmitotic Transcriptional Reactivation.” <i>Genes &#38; Development</i>, vol. 34, no. 13–14, Cold Spring Harbor Laboratory Press, 2020, pp. 913–30, doi:<a href=\"https://doi.org/10.1101/gad.335794.119\">10.1101/gad.335794.119</a>.","apa":"Kang, H., Shokhirev, M. N., Xu, Z., Chandran, S., Dixon, J. R., &#38; Hetzer, M. (2020). Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. <i>Genes &#38; Development</i>. Cold Spring Harbor Laboratory Press. <a href=\"https://doi.org/10.1101/gad.335794.119\">https://doi.org/10.1101/gad.335794.119</a>","ieee":"H. Kang, M. N. Shokhirev, Z. Xu, S. Chandran, J. R. Dixon, and M. Hetzer, “Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation,” <i>Genes &#38; Development</i>, vol. 34, no. 13–14. Cold Spring Harbor Laboratory Press, pp. 913–930, 2020."},"month":"04","_id":"11057","scopus_import":"1"}]