[{"type":"journal_article","day":"17","publisher":"Elsevier BV","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","extern":"1","date_published":"2020-01-17T00:00:00Z","oa_version":"Preprint","year":"2020","date_updated":"2024-09-23T13:34:58Z","article_processing_charge":"No","citation":{"mla":"De Rosa, Alessandra, et al. “The Quest for Dual and Binary Supermassive Black Holes: A Multi-Messenger View.” <i>New Astronomy Reviews</i>, vol. 86, 101525, Elsevier BV, 2020, doi:<a href=\"https://doi.org/10.1016/j.newar.2020.101525\">10.1016/j.newar.2020.101525</a>.","short":"A. De Rosa, C. Vignali, T. Bogdanović, P.R. Capelo, M. Charisi, M. Dotti, B. Husemann, E. Lusso, L. Mayer, Z. Paragi, J. Runnoe, A. Sesana, L. Steinborn, S. Bianchi, M. Colpi, L. del Valle, S. Frey, K.É. Gabányi, M. Giustini, M. Guainazzi, Z. Haiman, N. Herrera Ruiz, R. Herrero-Illana, K. Iwasawa, S. Komossa, D. Lena, N. Loiseau, M. Perez-Torres, E. Piconcelli, M. Volonteri, New Astronomy Reviews 86 (2020).","ieee":"A. De Rosa <i>et al.</i>, “The quest for dual and binary supermassive black holes: A multi-messenger view,” <i>New Astronomy Reviews</i>, vol. 86. Elsevier BV, 2020.","ama":"De Rosa A, Vignali C, Bogdanović T, et al. The quest for dual and binary supermassive black holes: A multi-messenger view. <i>New Astronomy Reviews</i>. 2020;86. doi:<a href=\"https://doi.org/10.1016/j.newar.2020.101525\">10.1016/j.newar.2020.101525</a>","apa":"De Rosa, A., Vignali, C., Bogdanović, T., Capelo, P. R., Charisi, M., Dotti, M., … Volonteri, M. (2020). The quest for dual and binary supermassive black holes: A multi-messenger view. <i>New Astronomy Reviews</i>. Elsevier BV. <a href=\"https://doi.org/10.1016/j.newar.2020.101525\">https://doi.org/10.1016/j.newar.2020.101525</a>","chicago":"De Rosa, Alessandra, Cristian Vignali, Tamara Bogdanović, Pedro R. Capelo, Maria Charisi, Massimo Dotti, Bernd Husemann, et al. “The Quest for Dual and Binary Supermassive Black Holes: A Multi-Messenger View.” <i>New Astronomy Reviews</i>. Elsevier BV, 2020. <a href=\"https://doi.org/10.1016/j.newar.2020.101525\">https://doi.org/10.1016/j.newar.2020.101525</a>.","ista":"De Rosa A, Vignali C, Bogdanović T, Capelo PR, Charisi M, Dotti M, Husemann B, Lusso E, Mayer L, Paragi Z, Runnoe J, Sesana A, Steinborn L, Bianchi S, Colpi M, del Valle L, Frey S, Gabányi KÉ, Giustini M, Guainazzi M, Haiman Z, Herrera Ruiz N, Herrero-Illana R, Iwasawa K, Komossa S, Lena D, Loiseau N, Perez-Torres M, Piconcelli E, Volonteri M. 2020. The quest for dual and binary supermassive black holes: A multi-messenger view. New Astronomy Reviews. 86, 101525."},"_id":"17600","title":"The quest for dual and binary supermassive black holes: A multi-messenger view","month":"01","doi":"10.1016/j.newar.2020.101525","article_type":"original","arxiv":1,"main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2001.06293"}],"publication_identifier":{"issn":["1387-6473"]},"oa":1,"author":[{"last_name":"De Rosa","full_name":"De Rosa, Alessandra","first_name":"Alessandra"},{"full_name":"Vignali, Cristian","last_name":"Vignali","first_name":"Cristian"},{"full_name":"Bogdanović, Tamara","last_name":"Bogdanović","first_name":"Tamara"},{"first_name":"Pedro R.","full_name":"Capelo, Pedro R.","last_name":"Capelo"},{"last_name":"Charisi","full_name":"Charisi, Maria","first_name":"Maria"},{"first_name":"Massimo","last_name":"Dotti","full_name":"Dotti, Massimo"},{"full_name":"Husemann, Bernd","last_name":"Husemann","first_name":"Bernd"},{"first_name":"Elisabeta","last_name":"Lusso","full_name":"Lusso, Elisabeta"},{"first_name":"Lucio","last_name":"Mayer","full_name":"Mayer, Lucio"},{"full_name":"Paragi, Zsolt","last_name":"Paragi","first_name":"Zsolt"},{"full_name":"Runnoe, Jessie","last_name":"Runnoe","first_name":"Jessie"},{"full_name":"Sesana, Alberto","last_name":"Sesana","first_name":"Alberto"},{"first_name":"Lisa","last_name":"Steinborn","full_name":"Steinborn, Lisa"},{"last_name":"Bianchi","full_name":"Bianchi, Stefano","first_name":"Stefano"},{"last_name":"Colpi","full_name":"Colpi, Monica","first_name":"Monica"},{"full_name":"del Valle, Luciano","last_name":"del Valle","first_name":"Luciano"},{"last_name":"Frey","full_name":"Frey, Sándor","first_name":"Sándor"},{"full_name":"Gabányi, Krisztina É.","last_name":"Gabányi","first_name":"Krisztina É."},{"last_name":"Giustini","full_name":"Giustini, Margherita","first_name":"Margherita"},{"full_name":"Guainazzi, Matteo","last_name":"Guainazzi","first_name":"Matteo"},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","full_name":"Haiman, Zoltán","last_name":"Haiman"},{"first_name":"Noelia","last_name":"Herrera Ruiz","full_name":"Herrera Ruiz, Noelia"},{"first_name":"Rubén","last_name":"Herrero-Illana","full_name":"Herrero-Illana, Rubén"},{"full_name":"Iwasawa, Kazushi","last_name":"Iwasawa","first_name":"Kazushi"},{"first_name":"S.","full_name":"Komossa, S.","last_name":"Komossa"},{"full_name":"Lena, Davide","last_name":"Lena","first_name":"Davide"},{"first_name":"Nora","last_name":"Loiseau","full_name":"Loiseau, Nora"},{"full_name":"Perez-Torres, Miguel","last_name":"Perez-Torres","first_name":"Miguel"},{"first_name":"Enrico","last_name":"Piconcelli","full_name":"Piconcelli, Enrico"},{"full_name":"Volonteri, Marta","last_name":"Volonteri","first_name":"Marta"}],"publication":"New Astronomy Reviews","scopus_import":"1","intvolume":"        86","abstract":[{"lang":"eng","text":"The quest for binary and dual supermassive black holes (SMBHs) at the dawn of the multi-messenger era is compelling. Detecting dual active galactic nuclei (AGN) – active SMBHs at projected separations larger than several parsecs – and binary AGN – probing the scale where SMBHs are bound in a Keplerian binary – is an observational challenge. The study of AGN pairs (either dual or binary) also represents an overarching theoretical problem in cosmology and astrophysics. The AGN triggering calls for detailed knowledge of the hydrodynamical conditions of gas in the imminent surroundings of the SMBHs and, at the same time, their duality calls for detailed knowledge on how galaxies assemble through major and minor mergers and grow fed by matter along the filaments of the cosmic web. This review describes the techniques used across the electromagnetic spectrum to detect dual and binary AGN candidates and proposes new avenues for their search. The current observational status is compared with the state-of-the-art numerical simulations and models for formation of dual and binary AGN. Binary SMBHs are among the loudest sources of gravitational waves (GWs) in the Universe. The search for a background of GWs at nHz frequencies from inspiralling SMBHs at low redshifts, and the direct detection of signals from their coalescence by the Laser Interferometer Space Antenna in the next decade, make this a theme of major interest for multi-messenger astrophysics. This review discusses the future facilities and observational strategies that are likely to significantly advance this fascinating field."}],"article_number":"101525","volume":86,"quality_controlled":"1","external_id":{"arxiv":["2001.06293"]},"date_created":"2024-09-05T13:07:32Z","language":[{"iso":"eng"}],"publication_status":"published"},{"publication_identifier":{"issn":["0004-637X","1538-4357"]},"oa":1,"main_file_link":[{"url":" https://doi.org/10.48550/arXiv.1911.05506","open_access":"1"}],"intvolume":"       901","publication":"The Astrophysical Journal","author":[{"first_name":"Paul C.","last_name":"Duffell","full_name":"Duffell, Paul C."},{"first_name":"Daniel","full_name":"D’Orazio, Daniel","last_name":"D’Orazio"},{"full_name":"Derdzinski, Andrea","last_name":"Derdzinski","first_name":"Andrea"},{"id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","full_name":"Haiman, Zoltán","last_name":"Haiman"},{"full_name":"MacFadyen, Andrew","last_name":"MacFadyen","first_name":"Andrew"},{"full_name":"Rosen, Anna L.","last_name":"Rosen","first_name":"Anna L."},{"first_name":"Jonathan","full_name":"Zrake, Jonathan","last_name":"Zrake"}],"scopus_import":"1","quality_controlled":"1","volume":901,"article_number":"25","abstract":[{"text":"Using numerical hydrodynamics calculations and a novel method for densely sampling parameter space, we measure the accretion and torque on a binary system from a circumbinary disk. In agreement with some earlier studies, we find that the net torque on the binary is positive for mass ratios close to unity, and that accretion always drives the binary toward equal mass. Accretion variability depends sensitively on the numerical sink prescription, but the torque and relative accretion onto each component do not depend on the sink timescale. Positive torque and highly variable accretion occurs only for mass ratios greater than around 0.05. This means that for mass ratios below 0.05, the binary would migrate inward until the secondary accreted sufficient mass, after which it would execute a U-turn and migrate outward. We explore a range of viscosities, from α = 0.03 to α = 0.15, and find that this outward torque is proportional to the viscous torque, so that torque per unit accreted mass is independent of α. Dependence of accretion and torque on mass ratio is explored in detail, densely sampling mass ratios between 0.01 and unity. For mass ratio q > 0.2, accretion variability is found to exhibit a distinct sawtooth pattern, typically with a five-orbit cycle that provides a smoking gun prediction for variable quasars observed over long periods, as a potential means to confirm the presence of a binary.","lang":"eng"}],"publication_status":"published","language":[{"iso":"eng"}],"date_created":"2024-09-05T13:08:20Z","external_id":{"arxiv":["1911.05506"]},"status":"public","issue":"1","day":"17","publisher":"American Astronomical Society","type":"journal_article","date_updated":"2024-09-23T13:39:03Z","year":"2020","oa_version":"Preprint","date_published":"2020-09-17T00:00:00Z","extern":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","month":"09","title":"Circumbinary disks: Accretion and torque as a function of mass ratio and disk viscosity","_id":"17601","citation":{"apa":"Duffell, P. C., D’Orazio, D., Derdzinski, A., Haiman, Z., MacFadyen, A., Rosen, A. L., &#38; Zrake, J. (2020). Circumbinary disks: Accretion and torque as a function of mass ratio and disk viscosity. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/abab95\">https://doi.org/10.3847/1538-4357/abab95</a>","ama":"Duffell PC, D’Orazio D, Derdzinski A, et al. Circumbinary disks: Accretion and torque as a function of mass ratio and disk viscosity. <i>The Astrophysical Journal</i>. 2020;901(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/abab95\">10.3847/1538-4357/abab95</a>","ista":"Duffell PC, D’Orazio D, Derdzinski A, Haiman Z, MacFadyen A, Rosen AL, Zrake J. 2020. Circumbinary disks: Accretion and torque as a function of mass ratio and disk viscosity. The Astrophysical Journal. 901(1), 25.","chicago":"Duffell, Paul C., Daniel D’Orazio, Andrea Derdzinski, Zoltán Haiman, Andrew MacFadyen, Anna L. Rosen, and Jonathan Zrake. “Circumbinary Disks: Accretion and Torque as a Function of Mass Ratio and Disk Viscosity.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2020. <a href=\"https://doi.org/10.3847/1538-4357/abab95\">https://doi.org/10.3847/1538-4357/abab95</a>.","short":"P.C. Duffell, D. D’Orazio, A. Derdzinski, Z. Haiman, A. MacFadyen, A.L. Rosen, J. Zrake, The Astrophysical Journal 901 (2020).","mla":"Duffell, Paul C., et al. “Circumbinary Disks: Accretion and Torque as a Function of Mass Ratio and Disk Viscosity.” <i>The Astrophysical Journal</i>, vol. 901, no. 1, 25, American Astronomical Society, 2020, doi:<a href=\"https://doi.org/10.3847/1538-4357/abab95\">10.3847/1538-4357/abab95</a>.","ieee":"P. C. Duffell <i>et al.</i>, “Circumbinary disks: Accretion and torque as a function of mass ratio and disk viscosity,” <i>The Astrophysical Journal</i>, vol. 901, no. 1. American Astronomical Society, 2020."},"article_processing_charge":"No","arxiv":1,"article_type":"original","doi":"10.3847/1538-4357/abab95"},{"article_type":"original","doi":"10.3847/1538-4357/aba432","arxiv":1,"citation":{"ieee":"C. Tiede, J. Zrake, A. MacFadyen, and Z. Haiman, “Gas-driven inspiral of binaries in thin accretion disks,” <i>The Astrophysical Journal</i>, vol. 900, no. 1. American Astronomical Society, 2020.","short":"C. Tiede, J. Zrake, A. MacFadyen, Z. Haiman, The Astrophysical Journal 900 (2020).","mla":"Tiede, Christopher, et al. “Gas-Driven Inspiral of Binaries in Thin Accretion Disks.” <i>The Astrophysical Journal</i>, vol. 900, no. 1, 43, American Astronomical Society, 2020, doi:<a href=\"https://doi.org/10.3847/1538-4357/aba432\">10.3847/1538-4357/aba432</a>.","chicago":"Tiede, Christopher, Jonathan Zrake, Andrew MacFadyen, and Zoltán Haiman. “Gas-Driven Inspiral of Binaries in Thin Accretion Disks.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2020. <a href=\"https://doi.org/10.3847/1538-4357/aba432\">https://doi.org/10.3847/1538-4357/aba432</a>.","ista":"Tiede C, Zrake J, MacFadyen A, Haiman Z. 2020. Gas-driven inspiral of binaries in thin accretion disks. The Astrophysical Journal. 900(1), 43.","ama":"Tiede C, Zrake J, MacFadyen A, Haiman Z. Gas-driven inspiral of binaries in thin accretion disks. <i>The Astrophysical Journal</i>. 2020;900(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/aba432\">10.3847/1538-4357/aba432</a>","apa":"Tiede, C., Zrake, J., MacFadyen, A., &#38; Haiman, Z. (2020). Gas-driven inspiral of binaries in thin accretion disks. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/aba432\">https://doi.org/10.3847/1538-4357/aba432</a>"},"article_processing_charge":"No","month":"08","title":"Gas-driven inspiral of binaries in thin accretion disks","_id":"17604","extern":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_updated":"2024-09-23T13:59:30Z","oa_version":"Preprint","year":"2020","date_published":"2020-08-28T00:00:00Z","issue":"1","day":"28","type":"journal_article","publisher":"American Astronomical Society","status":"public","language":[{"iso":"eng"}],"date_created":"2024-09-05T13:12:20Z","external_id":{"arxiv":["2005.09555"]},"publication_status":"published","article_number":"43","abstract":[{"lang":"eng","text":"Numerical studies of gas accretion onto supermassive black hole binaries (SMBHBs) have generally been limited to conditions where the circumbinary disk (CBD) is 10-100 times thicker than expected for disks in active galactic nuclei (AGN). This discrepancy arises from technical limitations, and also from publication bias toward replicating fiducial numerical models. Here we present the first systematic study of how the binary's orbital evolution varies with disk scale height. We report three key results: (1) Binary orbital evolution switches from outspiralling for warm disks (aspect ratio ~0.1), to inspiralling for more realistic cooler, thinner disks at a critical aspect ratio ~0.04, corresponding to orbital Mach number ~25. (2) The net torque on the binary arises from a competition between positive torque from gas orbiting close to the black holes, and negative torque from the inner edge of the CBD, which is denser for thinner disks. This leads to increasingly negative net torques on the binary for increasingly thin disks. (3) The accretion rate is modestly suppressed with increasing Mach number. We discuss how our results may influence modeling of the nano-Hz gravitational wave background, as well as estimates of the LISA merger event rate."}],"quality_controlled":"1","volume":900,"intvolume":"       900","scopus_import":"1","publication":"The Astrophysical Journal","author":[{"first_name":"Christopher","full_name":"Tiede, Christopher","last_name":"Tiede"},{"first_name":"Jonathan","last_name":"Zrake","full_name":"Zrake, Jonathan"},{"last_name":"MacFadyen","full_name":"MacFadyen, Andrew","first_name":"Andrew"},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","full_name":"Haiman, Zoltán","last_name":"Haiman"}],"main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2005.09555","open_access":"1"}],"oa":1,"publication_identifier":{"issn":["0004-637X","1538-4357"]}},{"language":[{"iso":"eng"}],"external_id":{"arxiv":["1911.11142"]},"date_created":"2024-09-05T13:13:33Z","publication_status":"published","abstract":[{"lang":"eng","text":"Despite the rapidly growing number of stellar-mass binary black hole mergers discovered through gravitational waves, the origin of these binaries is still not known. In galactic centers, black holes can be brought to each others' proximity by dynamical processes, resulting in mergers. It is also possible that black holes formed in previous mergers encounter new black holes, resulting in so-called hierarchical mergers. Hierarchical events carry signatures such as higher-than-usual black hole mass and spin. Here we show that the recently reported gravitational-wave candidate, GW170817A, could be the result of such a hierarchical merger. In particular, its chirp mass ∼40 M⊙ and effective spin of χeff ∼ 0.5 are the typically expected values from hierarchical mergers within the disks of active galactic nuclei. We find that the reconstructed parameters of GW170817A strongly favor a hierarchical merger origin over having been produced by an isolated binary origin (with an odds ratio of > 10^3)."}],"article_number":"L20","quality_controlled":"1","volume":890,"intvolume":"       890","publication":"The Astrophysical Journal Letters","author":[{"first_name":"V.","last_name":"Gayathri","full_name":"Gayathri, V."},{"full_name":"Bartos, I.","last_name":"Bartos","first_name":"I."},{"last_name":"Haiman","full_name":"Haiman, Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán"},{"first_name":"S.","full_name":"Klimenko, S.","last_name":"Klimenko"},{"full_name":"Kocsis, B.","last_name":"Kocsis","first_name":"B."},{"last_name":"Márka","full_name":"Márka, S.","first_name":"S."},{"full_name":"Yang, Y.","last_name":"Yang","first_name":"Y."}],"scopus_import":"1","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.1911.11142","open_access":"1"}],"publication_identifier":{"issn":["2041-8205","2041-8213"]},"oa":1,"doi":"10.3847/2041-8213/ab745d","article_type":"original","arxiv":1,"citation":{"ieee":"V. Gayathri <i>et al.</i>, “GW170817A as a hierarchical black hole merger,” <i>The Astrophysical Journal Letters</i>, vol. 890, no. 2. American Astronomical Society, 2020.","mla":"Gayathri, V., et al. “GW170817A as a Hierarchical Black Hole Merger.” <i>The Astrophysical Journal Letters</i>, vol. 890, no. 2, L20, American Astronomical Society, 2020, doi:<a href=\"https://doi.org/10.3847/2041-8213/ab745d\">10.3847/2041-8213/ab745d</a>.","short":"V. Gayathri, I. Bartos, Z. Haiman, S. Klimenko, B. Kocsis, S. Márka, Y. Yang, The Astrophysical Journal Letters 890 (2020).","chicago":"Gayathri, V., I. Bartos, Zoltán Haiman, S. Klimenko, B. Kocsis, S. Márka, and Y. Yang. “GW170817A as a Hierarchical Black Hole Merger.” <i>The Astrophysical Journal Letters</i>. American Astronomical Society, 2020. <a href=\"https://doi.org/10.3847/2041-8213/ab745d\">https://doi.org/10.3847/2041-8213/ab745d</a>.","ista":"Gayathri V, Bartos I, Haiman Z, Klimenko S, Kocsis B, Márka S, Yang Y. 2020. GW170817A as a hierarchical black hole merger. The Astrophysical Journal Letters. 890(2), L20.","ama":"Gayathri V, Bartos I, Haiman Z, et al. GW170817A as a hierarchical black hole merger. <i>The Astrophysical Journal Letters</i>. 2020;890(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ab745d\">10.3847/2041-8213/ab745d</a>","apa":"Gayathri, V., Bartos, I., Haiman, Z., Klimenko, S., Kocsis, B., Márka, S., &#38; Yang, Y. (2020). GW170817A as a hierarchical black hole merger. <i>The Astrophysical Journal Letters</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/2041-8213/ab745d\">https://doi.org/10.3847/2041-8213/ab745d</a>"},"article_processing_charge":"No","title":"GW170817A as a hierarchical black hole merger","month":"02","_id":"17605","extern":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2020","oa_version":"Preprint","date_updated":"2024-09-23T14:04:29Z","date_published":"2020-02-18T00:00:00Z","type":"journal_article","publisher":"American Astronomical Society","day":"18","issue":"2","status":"public"},{"publication_status":"published","date_created":"2024-09-05T13:15:59Z","external_id":{"arxiv":["2007.04781"]},"language":[{"iso":"eng"}],"volume":901,"quality_controlled":"1","article_number":"L34","abstract":[{"text":"The heaviest neutron stars and lightest black holes expected to be produced by stellar evolution leave the mass-range 2.2 M⊙≲m≲5 M⊙ largely unpopulated. Objects found in this so-called lower mass gap likely originate from a distinct astrophysical process. Such an object, with mass 2.6 M⊙ was recently detected in the binary merger GW190814 through gravitational waves by LIGO/Virgo. Here we show that black holes in the mass gap are naturally assembled through mergers and accretion in AGN disks, and can subsequently participate in additional mergers. We compute the properties of AGN-assisted mergers involving neutron stars and black holes, accounting for accretion. We find that mergers in which one of the objects is in the lower mass gap represent up to 4% of AGN-assisted mergers detectable by LIGO/Virgo. The lighter object of GW190814, with mass 2.6 M⊙, could have grown in an AGN disk through accretion. We find that the unexpectedly high total mass of 3.4 M⊙ observed in the neutron star merger GW190425 may also be due to accretion in an AGN disk.","lang":"eng"}],"publication":"The Astrophysical Journal Letters","author":[{"full_name":"Yang, Y.","last_name":"Yang","first_name":"Y."},{"first_name":"V.","last_name":"Gayathri","full_name":"Gayathri, V."},{"full_name":"Bartos, I.","last_name":"Bartos","first_name":"I."},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","full_name":"Haiman, Zoltán"},{"first_name":"M.","last_name":"Safarzadeh","full_name":"Safarzadeh, M."},{"full_name":"Tagawa, H.","last_name":"Tagawa","first_name":"H."}],"scopus_import":"1","intvolume":"       901","oa":1,"publication_identifier":{"issn":["2041-8205","2041-8213"]},"main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2007.04781","open_access":"1"}],"arxiv":1,"article_type":"original","doi":"10.3847/2041-8213/abb940","_id":"17607","month":"10","title":"Black hole formation in the lower mass gap through mergers and accretion in AGN disks","article_processing_charge":"No","citation":{"ama":"Yang Y, Gayathri V, Bartos I, Haiman Z, Safarzadeh M, Tagawa H. Black hole formation in the lower mass gap through mergers and accretion in AGN disks. <i>The Astrophysical Journal Letters</i>. 2020;901(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/abb940\">10.3847/2041-8213/abb940</a>","apa":"Yang, Y., Gayathri, V., Bartos, I., Haiman, Z., Safarzadeh, M., &#38; Tagawa, H. (2020). Black hole formation in the lower mass gap through mergers and accretion in AGN disks. <i>The Astrophysical Journal Letters</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/2041-8213/abb940\">https://doi.org/10.3847/2041-8213/abb940</a>","chicago":"Yang, Y., V. Gayathri, I. Bartos, Zoltán Haiman, M. Safarzadeh, and H. Tagawa. “Black Hole Formation in the Lower Mass Gap through Mergers and Accretion in AGN Disks.” <i>The Astrophysical Journal Letters</i>. American Astronomical Society, 2020. <a href=\"https://doi.org/10.3847/2041-8213/abb940\">https://doi.org/10.3847/2041-8213/abb940</a>.","ista":"Yang Y, Gayathri V, Bartos I, Haiman Z, Safarzadeh M, Tagawa H. 2020. Black hole formation in the lower mass gap through mergers and accretion in AGN disks. The Astrophysical Journal Letters. 901(2), L34.","short":"Y. Yang, V. Gayathri, I. Bartos, Z. Haiman, M. Safarzadeh, H. Tagawa, The Astrophysical Journal Letters 901 (2020).","mla":"Yang, Y., et al. “Black Hole Formation in the Lower Mass Gap through Mergers and Accretion in AGN Disks.” <i>The Astrophysical Journal Letters</i>, vol. 901, no. 2, L34, American Astronomical Society, 2020, doi:<a href=\"https://doi.org/10.3847/2041-8213/abb940\">10.3847/2041-8213/abb940</a>.","ieee":"Y. Yang, V. Gayathri, I. Bartos, Z. Haiman, M. Safarzadeh, and H. Tagawa, “Black hole formation in the lower mass gap through mergers and accretion in AGN disks,” <i>The Astrophysical Journal Letters</i>, vol. 901, no. 2. American Astronomical Society, 2020."},"date_published":"2020-10-01T00:00:00Z","date_updated":"2024-09-23T14:16:49Z","year":"2020","oa_version":"Preprint","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","extern":"1","status":"public","issue":"2","type":"journal_article","day":"01","publisher":"American Astronomical Society"},{"citation":{"short":"T.D. Browning, W. Sawin, Annals of Mathematics 191 (2020) 893–948.","mla":"Browning, Timothy D., and Will Sawin. “A Geometric Version of the Circle Method.” <i>Annals of Mathematics</i>, vol. 191, no. 3, Princeton University, 2020, pp. 893–948, doi:<a href=\"https://doi.org/10.4007/annals.2020.191.3.4\">10.4007/annals.2020.191.3.4</a>.","ieee":"T. D. Browning and W. Sawin, “A geometric version of the circle method,” <i>Annals of Mathematics</i>, vol. 191, no. 3. Princeton University, pp. 893–948, 2020.","apa":"Browning, T. D., &#38; Sawin, W. (2020). A geometric version of the circle method. <i>Annals of Mathematics</i>. Princeton University. <a href=\"https://doi.org/10.4007/annals.2020.191.3.4\">https://doi.org/10.4007/annals.2020.191.3.4</a>","ama":"Browning TD, Sawin W. A geometric version of the circle method. <i>Annals of Mathematics</i>. 2020;191(3):893-948. doi:<a href=\"https://doi.org/10.4007/annals.2020.191.3.4\">10.4007/annals.2020.191.3.4</a>","ista":"Browning TD, Sawin W. 2020. A geometric version of the circle method. Annals of Mathematics. 191(3), 893–948.","chicago":"Browning, Timothy D, and Will Sawin. “A Geometric Version of the Circle Method.” <i>Annals of Mathematics</i>. Princeton University, 2020. <a href=\"https://doi.org/10.4007/annals.2020.191.3.4\">https://doi.org/10.4007/annals.2020.191.3.4</a>."},"article_processing_charge":"No","title":"A geometric version of the circle method","month":"05","_id":"177","doi":"10.4007/annals.2020.191.3.4","publist_id":"7744","article_type":"original","arxiv":1,"day":"01","publisher":"Princeton University","type":"journal_article","issue":"3","status":"public","page":"893-948","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2020","oa_version":"Preprint","date_updated":"2024-10-21T06:02:25Z","date_published":"2020-05-01T00:00:00Z","abstract":[{"text":"We develop a geometric version of the circle method and use it to compute the compactly supported cohomology of the space of rational curves through a point on a smooth affine hypersurface of sufficiently low degree.","lang":"eng"}],"quality_controlled":"1","volume":191,"language":[{"iso":"eng"}],"department":[{"_id":"TiBr"}],"external_id":{"isi":["000526986300004"],"arxiv":["1711.10451"]},"date_created":"2018-12-11T11:45:02Z","publication_status":"published","main_file_link":[{"url":"https://arxiv.org/abs/1711.10451","open_access":"1"}],"oa":1,"intvolume":"       191","isi":1,"scopus_import":"1","publication":"Annals of Mathematics","author":[{"first_name":"Timothy D","id":"35827D50-F248-11E8-B48F-1D18A9856A87","last_name":"Browning","full_name":"Browning, Timothy D","orcid":"0000-0002-8314-0177"},{"full_name":"Sawin, Will","last_name":"Sawin","first_name":"Will"}]},{"intvolume":"        14","isi":1,"ec_funded":1,"publication":"Frontiers in Cellular Neuroscience","scopus_import":"1","file_date_updated":"2020-07-14T12:48:01Z","author":[{"orcid":"0000-0002-6170-2546","id":"2B7846DC-F248-11E8-B48F-1D18A9856A87","first_name":"Kohgaku","full_name":"Eguchi, Kohgaku","last_name":"Eguchi"},{"last_name":"Velicky","full_name":"Velicky, Philipp","first_name":"Philipp","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2340-7431"},{"id":"3C054040-F248-11E8-B48F-1D18A9856A87","first_name":"Elena","full_name":"Hollergschwandtner, Elena","last_name":"Hollergschwandtner"},{"first_name":"Makoto","last_name":"Itakura","full_name":"Itakura, Makoto"},{"last_name":"Fukazawa","full_name":"Fukazawa, Yugo","first_name":"Yugo"},{"orcid":"0000-0001-8559-3973","last_name":"Danzl","full_name":"Danzl, Johann G","first_name":"Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444"}],"publication_identifier":{"issn":["1662-5102"]},"oa":1,"pmid":1,"file":[{"access_level":"open_access","relation":"main_file","checksum":"1c145123c6f8dc3e2e4bd5a66a1ad60e","content_type":"application/pdf","date_updated":"2020-07-14T12:48:01Z","file_name":"2020_FrontiersCellularNeurosc_Eguchi.pdf","creator":"dernst","date_created":"2020-04-20T10:59:49Z","file_id":"7668","file_size":9227283}],"publication_status":"published","language":[{"iso":"eng"}],"corr_author":"1","date_created":"2020-04-19T22:00:55Z","department":[{"_id":"JoDa"},{"_id":"RySh"}],"external_id":{"pmid":["32265664"],"isi":["000525582200001"]},"quality_controlled":"1","volume":14,"article_number":"63","abstract":[{"text":"Acute brain slice preparation is a powerful experimental model for investigating the characteristics of synaptic function in the brain. Although brain tissue is usually cut at ice-cold temperature (CT) to facilitate slicing and avoid neuronal damage, exposure to CT causes molecular and architectural changes of synapses. To address these issues, we investigated ultrastructural and electrophysiological features of synapses in mouse acute cerebellar slices prepared at ice-cold and physiological temperature (PT). In the slices prepared at CT, we found significant spine loss and reconstruction, synaptic vesicle rearrangement and decrease in synaptic proteins, all of which were not detected in slices prepared at PT. Consistent with these structural findings, slices prepared at PT showed higher release probability. Furthermore, preparation at PT allows electrophysiological recording immediately after slicing resulting in higher detectability of long-term depression (LTD) after motor learning compared with that at CT. These results indicate substantial advantages of the slice preparation at PT for investigating synaptic functions in different physiological conditions.","lang":"eng"}],"date_updated":"2025-06-12T07:16:39Z","year":"2020","oa_version":"Published Version","has_accepted_license":"1","date_published":"2020-03-19T00:00:00Z","project":[{"_id":"2659CC84-B435-11E9-9278-68D0E5697425","grant_number":"793482","call_identifier":"H2020","name":"Ultrastructural analysis of phosphoinositides in nerve terminals: distribution, dynamics and physiological roles in synaptic transmission"},{"grant_number":"694539","_id":"25CA28EA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"In situ analysis of single channel subunit composition in neurons: physiological implication in synaptic plasticity and behaviour"},{"grant_number":"I03600","_id":"265CB4D0-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Optical control of synaptic function via adhesion molecules"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","day":"19","publisher":"Frontiers Media","type":"journal_article","ddc":["570"],"article_type":"original","doi":"10.3389/fncel.2020.00063","month":"03","title":"Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions","_id":"7665","citation":{"apa":"Eguchi, K., Velicky, P., Saeckl, E., Itakura, M., Fukazawa, Y., Danzl, J. G., &#38; Shigemoto, R. (2020). Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>","ama":"Eguchi K, Velicky P, Saeckl E, et al. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. 2020;14. doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>","ista":"Eguchi K, Velicky P, Saeckl E, Itakura M, Fukazawa Y, Danzl JG, Shigemoto R. 2020. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. Frontiers in Cellular Neuroscience. 14, 63.","chicago":"Eguchi, Kohgaku, Philipp Velicky, Elena Saeckl, Makoto Itakura, Yugo Fukazawa, Johann G Danzl, and Ryuichi Shigemoto. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>.","short":"K. Eguchi, P. Velicky, E. Saeckl, M. Itakura, Y. Fukazawa, J.G. Danzl, R. Shigemoto, Frontiers in Cellular Neuroscience 14 (2020).","mla":"Eguchi, Kohgaku, et al. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>, vol. 14, 63, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>.","ieee":"K. Eguchi <i>et al.</i>, “Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions,” <i>Frontiers in Cellular Neuroscience</i>, vol. 14. Frontiers Media, 2020."},"article_processing_charge":"Yes (via OA deal)"},{"acknowledgement":"This project has received funding from the European Research Council under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 78818 Alpha). It is also partially supported by the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant No. I02979-N35 of the Austrian Science Fund (FWF).","file":[{"date_updated":"2020-11-20T13:22:21Z","checksum":"f8cc96e497f00c38340b5dafe0cb91d7","content_type":"application/pdf","file_size":701673,"creator":"dernst","file_name":"2020_DiscreteCompGeo_Edelsbrunner.pdf","date_created":"2020-11-20T13:22:21Z","file_id":"8786","access_level":"open_access","relation":"main_file","success":1}],"oa":1,"publication_identifier":{"eissn":["14320444"],"issn":["01795376"]},"author":[{"last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9823-6833"},{"orcid":"0000-0002-4672-8297","last_name":"Ölsböck","full_name":"Ölsböck, Katharina","first_name":"Katharina","id":"4D4AA390-F248-11E8-B48F-1D18A9856A87"}],"scopus_import":"1","file_date_updated":"2020-11-20T13:22:21Z","publication":"Discrete and Computational Geometry","intvolume":"        64","isi":1,"ec_funded":1,"volume":64,"quality_controlled":"1","abstract":[{"lang":"eng","text":"Generalizing the decomposition of a connected planar graph into a tree and a dual tree, we prove a combinatorial analog of the classic Helmholtz–Hodge decomposition of a smooth vector field. Specifically, we show that for every polyhedral complex, K, and every dimension, p, there is a partition of the set of p-cells into a maximal p-tree, a maximal p-cotree, and a collection of p-cells whose cardinality is the p-th reduced Betti number of K. Given an ordering of the p-cells, this tri-partition is unique, and it can be computed by a matrix reduction algorithm that also constructs canonical bases of cycle and boundary groups."}],"publication_status":"published","date_created":"2020-04-19T22:00:56Z","department":[{"_id":"HeEd"}],"external_id":{"isi":["000520918800001"]},"language":[{"iso":"eng"}],"corr_author":"1","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publisher":"Springer Nature","type":"journal_article","day":"20","has_accepted_license":"1","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","name":"Alpha Shape Theory Extended","call_identifier":"H2020"},{"call_identifier":"FWF","name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"}],"date_published":"2020-03-20T00:00:00Z","date_updated":"2025-04-14T07:48:36Z","oa_version":"Published Version","year":"2020","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","page":"759-775","_id":"7666","month":"03","title":"Tri-partitions and bases of an ordered complex","article_processing_charge":"Yes (via OA deal)","citation":{"short":"H. Edelsbrunner, K. Ölsböck, Discrete and Computational Geometry 64 (2020) 759–775.","mla":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>, vol. 64, Springer Nature, 2020, pp. 759–75, doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>.","ieee":"H. Edelsbrunner and K. Ölsböck, “Tri-partitions and bases of an ordered complex,” <i>Discrete and Computational Geometry</i>, vol. 64. Springer Nature, pp. 759–775, 2020.","apa":"Edelsbrunner, H., &#38; Ölsböck, K. (2020). Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>","ama":"Edelsbrunner H, Ölsböck K. Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. 2020;64:759-775. doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>","ista":"Edelsbrunner H, Ölsböck K. 2020. Tri-partitions and bases of an ordered complex. Discrete and Computational Geometry. 64, 759–775.","chicago":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>."},"ddc":["510"],"article_type":"original","doi":"10.1007/s00454-020-00188-x"},{"ddc":["540"],"article_type":"original","doi":"10.1016/j.electacta.2020.137175","month":"12","title":"Surface and catalyst driven singlet oxygen formation in Li-O2 cells","_id":"7672","citation":{"apa":"Samojlov, A., Schuster, D., Kahr, J., &#38; Freunberger, S. A. (2020). Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>","ama":"Samojlov A, Schuster D, Kahr J, Freunberger SA. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. 2020;362(12). doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>","ista":"Samojlov A, Schuster D, Kahr J, Freunberger SA. 2020. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. Electrochimica Acta. 362(12), 137175.","chicago":"Samojlov, Aleksej, David Schuster, Jürgen Kahr, and Stefan Alexander Freunberger. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>.","short":"A. Samojlov, D. Schuster, J. Kahr, S.A. Freunberger, Electrochimica Acta 362 (2020).","mla":"Samojlov, Aleksej, et al. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>, vol. 362, no. 12, 137175, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>.","ieee":"A. Samojlov, D. Schuster, J. Kahr, and S. A. Freunberger, “Surface and catalyst driven singlet oxygen formation in Li-O2 cells,” <i>Electrochimica Acta</i>, vol. 362, no. 12. Elsevier, 2020."},"article_processing_charge":"Yes (via OA deal)","date_updated":"2024-10-09T20:59:27Z","oa_version":"Published Version","year":"2020","has_accepted_license":"1","date_published":"2020-12-01T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"status":"public","issue":"12","day":"01","type":"journal_article","publisher":"Elsevier","publication_status":"published","language":[{"iso":"eng"}],"corr_author":"1","date_created":"2020-04-20T19:29:31Z","external_id":{"isi":["000582869700060"]},"department":[{"_id":"StFr"}],"quality_controlled":"1","volume":362,"article_number":"137175","abstract":[{"text":"Large overpotentials upon discharge and charge of Li-O2 cells have motivated extensive research into heterogeneous solid electrocatalysts or non-carbon electrodes with the aim to improve rate capability, round-trip efficiency and cycle life. These features are equally governed by parasitic reactions, which are now recognized to be caused by the highly reactive singlet oxygen (1O2). However, the link between the presence of electrocatalysts and 1O2 formation in metal-O2 cells is unknown. Here, we show that, compared to pristine carbon black electrodes, a representative selection of electrocatalysts or non-carbon electrodes (noble metal, transition metal compounds) may both slightly reduce or severely increase the 1O2 formation. The individual reaction steps, where the surfaces impact the 1O2 yield are deciphered, showing that 1O2 yield from superoxide disproportionation as well as the decomposition of trace H2O2 are sensitive to catalysts. Transition metal compounds in general are prone to increase 1O2.","lang":"eng"}],"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","intvolume":"       362","isi":1,"publication":"Electrochimica Acta","file_date_updated":"2020-10-01T13:20:45Z","scopus_import":"1","author":[{"full_name":"Samojlov, Aleksej","last_name":"Samojlov","first_name":"Aleksej"},{"last_name":"Schuster","full_name":"Schuster, David","first_name":"David"},{"first_name":"Jürgen","last_name":"Kahr","full_name":"Kahr, Jürgen"},{"orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","first_name":"Stefan Alexander"}],"oa":1,"file":[{"relation":"main_file","access_level":"open_access","success":1,"content_type":"application/pdf","checksum":"1ab1aa2024d431e2a089ea336bc08298","date_updated":"2020-10-01T13:20:45Z","date_created":"2020-10-01T13:20:45Z","file_id":"8593","file_name":"2020_ElectrochimicaActa_Samojlov.pdf","creator":"dernst","file_size":1404030}],"acknowledgement":"S.A.F. thanks the International Society of Electrochemistry for awarding the Tajima Prize 2019 “in recognition of outstanding re- searches on Li-Air batteries by the use of a range of in-situ elec- trochemical methods to achieve comprehensive understanding of the reactions taking place at the oxygen electrode”. This article is dedicated to the special issue of Electrochmica Acta associated with the awarding conference. S.A.F. is indebted to and the Austrian Federal Ministry of Science, Research and Economy and the Austrian Research Promotion Agency (grant No. 845364 ) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 636069). The authors thank J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH and G. Strohmeier for help with HPLC measurements, S. Eder for cyclic voltammetry measurements, and C. Slugovc for discussions and continuous support. We thank S. Borisov for access and advice with fluorescence measurements. We thank EL-Cell GmbH, Hamburg, Germany for providing the PAT-Cell-Press electrochemical cell."},{"quality_controlled":"1","volume":26,"article_number":"30","abstract":[{"text":"For any free oriented Borel–Moore homology theory A, we construct an associative product on the A-theory of the stack of Higgs torsion sheaves over a projective curve C. We show that the resulting algebra AHa0C admits a natural shuffle presentation, and prove it is faithful when A is replaced with usual Borel–Moore homology groups. We also introduce moduli spaces of stable triples, heavily inspired by Nakajima quiver varieties, whose A-theory admits an AHa0C-action. These triples can be interpreted as certain sheaves on PC(ωC⊕OC). In particular, we obtain an action of AHa0C on the cohomology of Hilbert schemes of points on T∗C.","lang":"eng"}],"publication_status":"published","corr_author":"1","language":[{"iso":"eng"}],"date_created":"2020-04-26T22:00:44Z","external_id":{"isi":["000526036400001"],"arxiv":["1801.01429"]},"department":[{"_id":"TaHa"}],"oa":1,"publication_identifier":{"issn":["1022-1824"],"eissn":["1420-9020"]},"file":[{"relation":"main_file","access_level":"open_access","date_updated":"2020-07-14T12:48:02Z","content_type":"application/pdf","checksum":"2368c4662629b4759295eb365323b2ad","file_size":792469,"file_id":"7690","date_created":"2020-04-28T10:57:58Z","creator":"dernst","file_name":"2020_SelectaMathematica_Minets.pdf"}],"isi":1,"intvolume":"        26","publication":"Selecta Mathematica, New Series","file_date_updated":"2020-07-14T12:48:02Z","author":[{"orcid":"0000-0003-3883-1806","full_name":"Minets, Sasha","last_name":"Minets","first_name":"Sasha","id":"3E7C5304-F248-11E8-B48F-1D18A9856A87"}],"scopus_import":"1","month":"04","title":"Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces","_id":"7683","citation":{"ieee":"S. Minets, “Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces,” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2. Springer Nature, 2020.","short":"S. Minets, Selecta Mathematica, New Series 26 (2020).","mla":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2, 30, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>.","ista":"Minets S. 2020. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. Selecta Mathematica, New Series. 26(2), 30.","chicago":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>.","apa":"Minets, S. (2020). Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>","ama":"Minets S. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. 2020;26(2). doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>"},"article_processing_charge":"Yes (via OA deal)","ddc":["510"],"arxiv":1,"article_type":"original","doi":"10.1007/s00029-020-00553-x","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","issue":"2","type":"journal_article","publisher":"Springer Nature","day":"15","date_updated":"2025-05-20T10:38:32Z","year":"2020","oa_version":"Published Version","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"date_published":"2020-04-15T00:00:00Z","has_accepted_license":"1","user_id":"9947682f-b9fa-11ee-9c4a-b3ffaafe6614"},{"article_type":"original","doi":"10.1016/j.tplants.2020.04.001","citation":{"ieee":"H. Xue, Y. Zhang, and G. Xiao, “Neo-gibberellin signaling: Guiding the next generation of the green revolution,” <i>Trends in Plant Science</i>, vol. 25, no. 6. Elsevier, pp. 520–522, 2020.","short":"H. Xue, Y. Zhang, G. Xiao, Trends in Plant Science 25 (2020) 520–522.","mla":"Xue, Huidan, et al. “Neo-Gibberellin Signaling: Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>, vol. 25, no. 6, Elsevier, 2020, pp. 520–22, doi:<a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">10.1016/j.tplants.2020.04.001</a>.","chicago":"Xue, Huidan, Yuzhou Zhang, and Guanghui Xiao. “Neo-Gibberellin Signaling: Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">https://doi.org/10.1016/j.tplants.2020.04.001</a>.","ista":"Xue H, Zhang Y, Xiao G. 2020. Neo-gibberellin signaling: Guiding the next generation of the green revolution. Trends in Plant Science. 25(6), 520–522.","ama":"Xue H, Zhang Y, Xiao G. Neo-gibberellin signaling: Guiding the next generation of the green revolution. <i>Trends in Plant Science</i>. 2020;25(6):520-522. doi:<a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">10.1016/j.tplants.2020.04.001</a>","apa":"Xue, H., Zhang, Y., &#38; Xiao, G. (2020). Neo-gibberellin signaling: Guiding the next generation of the green revolution. <i>Trends in Plant Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">https://doi.org/10.1016/j.tplants.2020.04.001</a>"},"article_processing_charge":"No","month":"06","title":"Neo-gibberellin signaling: Guiding the next generation of the green revolution","_id":"7686","page":"520-522","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-06-25T10:59:39Z","oa_version":"None","year":"2020","date_published":"2020-06-01T00:00:00Z","issue":"6","day":"01","type":"journal_article","publisher":"Elsevier","status":"public","language":[{"iso":"eng"}],"date_created":"2020-04-26T22:00:46Z","department":[{"_id":"JiFr"}],"external_id":{"pmid":["32407691"],"isi":["000533518400003"]},"publication_status":"published","abstract":[{"text":"The agricultural green revolution spectacularly enhanced crop yield and lodging resistance with modified DELLA-mediated gibberellin signaling. However, this was achieved at the expense of reduced nitrogen-use efficiency (NUE). Recently, Wu et al. revealed novel gibberellin signaling that provides a blueprint for improving tillering and NUE in Green Revolution varieties (GRVs). ","lang":"eng"}],"quality_controlled":"1","volume":25,"isi":1,"intvolume":"        25","author":[{"full_name":"Xue, Huidan","last_name":"Xue","first_name":"Huidan"},{"orcid":"0000-0003-2627-6956","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87","first_name":"Yuzhou","full_name":"Zhang, Yuzhou","last_name":"Zhang"},{"full_name":"Xiao, Guanghui","last_name":"Xiao","first_name":"Guanghui"}],"publication":"Trends in Plant Science","scopus_import":"1","publication_identifier":{"issn":["1360-1385"]},"pmid":1},{"publisher":"Institute of Science and Technology Austria","day":"01","type":"research_data","file":[{"creator":"gkatsaro","file_name":"DOI_ZeroFieldSplitting.zip","date_created":"2020-05-01T15:13:28Z","file_id":"7786","file_size":5514403,"content_type":"application/x-zip-compressed","checksum":"d23c0cb9e2d19e14e2f902b88b97c05d","date_updated":"2020-07-14T12:48:02Z","access_level":"open_access","relation":"main_file"}],"status":"public","oa":1,"tmp":{"legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","short":"CC0 (1.0)","image":"/images/cc_0.png","name":"Creative Commons Public Domain Dedication (CC0 1.0)"},"author":[{"last_name":"Katsaros","full_name":"Katsaros, Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","first_name":"Georgios","orcid":"0000-0001-8342-202X"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:48:02Z","ec_funded":1,"has_accepted_license":"1","date_published":"2020-05-01T00:00:00Z","project":[{"name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS","call_identifier":"H2020","grant_number":"862046","_id":"237E5020-32DE-11EA-91FC-C7463DDC885E"},{"grant_number":"P32235","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","call_identifier":"FWF","name":"Towards scalable hut wire quantum devices"}],"year":"2020","oa_version":"Published Version","date_updated":"2025-04-15T08:39:16Z","article_processing_charge":"No","abstract":[{"lang":"eng","text":"These are the supplementary research data to the publication \"Zero field splitting of heavy-hole states in quantum dots\". All matrix files have the same format. Within each column the bias voltage is changed. Each column corresponds to either a different gate voltage or magnetic field. The voltage values are given in mV, the current values in pA. Find a specific description in the included Readme file.\r\n"}],"citation":{"ieee":"G. Katsaros, “Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots.’” Institute of Science and Technology Austria, 2020.","mla":"Katsaros, Georgios. <i>Supplementary Data for “Zero Field Splitting of Heavy-Hole States in Quantum Dots.”</i> Institute of Science and Technology Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","short":"G. Katsaros, (2020).","chicago":"Katsaros, Georgios. “Supplementary Data for ‘Zero Field Splitting of Heavy-Hole States in Quantum Dots.’” Institute of Science and Technology Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>.","ista":"Katsaros G. 2020. Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","ama":"Katsaros G. Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>","apa":"Katsaros, G. (2020). Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>"},"related_material":{"record":[{"id":"8203","relation":"used_in_publication","status":"public"}]},"_id":"7689","title":"Supplementary data for \"Zero field splitting of heavy-hole states in quantum dots\"","month":"05","department":[{"_id":"GeKa"}],"date_created":"2020-05-01T15:14:46Z","contributor":[{"last_name":"Katsaros","contributor_type":"contact_person","first_name":"Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87"}],"doi":"10.15479/AT:ISTA:7689","corr_author":"1","ddc":["530"]},{"project":[{"grant_number":"I03630","_id":"26538374-B435-11E9-9278-68D0E5697425","name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF"}],"date_published":"2020-07-01T00:00:00Z","year":"2020","oa_version":"Preprint","date_updated":"2025-04-15T07:32:09Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","page":"986-997","status":"public","publisher":"American Society of Plant Biologists","day":"01","type":"journal_article","issue":"3","doi":"10.1104/pp.20.00178","article_type":"original","_id":"7695","title":"High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits","month":"07","article_processing_charge":"No","citation":{"short":"J. Wang, E. Mylle, A.J. Johnson, N. Besbrugge, G. De Jaeger, J. Friml, R. Pleskot, D. van Damme, Plant Physiology 183 (2020) 986–997.","mla":"Wang, J., et al. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>, vol. 183, no. 3, American Society of Plant Biologists, 2020, pp. 986–97, doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>.","ieee":"J. Wang <i>et al.</i>, “High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits,” <i>Plant Physiology</i>, vol. 183, no. 3. American Society of Plant Biologists, pp. 986–997, 2020.","ama":"Wang J, Mylle E, Johnson AJ, et al. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. 2020;183(3):986-997. doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>","apa":"Wang, J., Mylle, E., Johnson, A. J., Besbrugge, N., De Jaeger, G., Friml, J., … van Damme, D. (2020). High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>","chicago":"Wang, J, E Mylle, Alexander J Johnson, N Besbrugge, G De Jaeger, Jiří Friml, R Pleskot, and D van Damme. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>. American Society of Plant Biologists, 2020. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>.","ista":"Wang J, Mylle E, Johnson AJ, Besbrugge N, De Jaeger G, Friml J, Pleskot R, van Damme D. 2020. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. Plant Physiology. 183(3), 986–997."},"author":[{"first_name":"J","last_name":"Wang","full_name":"Wang, J"},{"first_name":"E","full_name":"Mylle, E","last_name":"Mylle"},{"orcid":"0000-0002-2739-8843","full_name":"Johnson, Alexander J","last_name":"Johnson","first_name":"Alexander J","id":"46A62C3A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"N","full_name":"Besbrugge, N","last_name":"Besbrugge"},{"full_name":"De Jaeger, G","last_name":"De Jaeger","first_name":"G"},{"first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596"},{"full_name":"Pleskot, R","last_name":"Pleskot","first_name":"R"},{"first_name":"D","full_name":"van Damme, D","last_name":"van Damme"}],"publication":"Plant Physiology","scopus_import":"1","isi":1,"intvolume":"       183","pmid":1,"publication_identifier":{"issn":["0032-0889"],"eissn":["1532-2548"]},"oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2020.02.13.948109"}],"publication_status":"published","department":[{"_id":"JiFr"}],"external_id":{"pmid":["32321842"],"isi":["000550682000018"]},"date_created":"2020-04-29T15:23:00Z","language":[{"iso":"eng"}],"volume":183,"quality_controlled":"1","abstract":[{"text":"The TPLATE complex (TPC) is a key endocytic adaptor protein complex in plants. TPC in Arabidopsis (Arabidopsis thaliana) contains six evolutionarily conserved subunits and two plant-specific subunits, AtEH1/Pan1 and AtEH2/Pan1, although cytoplasmic proteins are not associated with the hexameric subcomplex in the cytoplasm. To investigate the dynamic assembly of the octameric TPC at the plasma membrane (PM), we performed state-of-the-art dual-color live cell imaging at physiological and lowered temperatures. Lowering the temperature slowed down endocytosis, thereby enhancing the temporal resolution of the differential recruitment of endocytic components. Under both normal and lowered temperature conditions, the core TPC subunit TPLATE and the AtEH/Pan1 proteins exhibited simultaneous recruitment at the PM. These results, together with co-localization analysis of different TPC subunits, allow us to conclude that TPC in plant cells is not recruited to the PM sequentially but as an octameric complex.","lang":"eng"}]},{"abstract":[{"lang":"eng","text":"* Morphogenesis and adaptive tropic growth in plants depend on gradients of the phytohormone auxin, mediated by the membrane‐based PIN‐FORMED (PIN) auxin transporters. PINs localize to a particular side of the plasma membrane (PM) or to the endoplasmic reticulum (ER) to directionally transport auxin and maintain intercellular and intracellular auxin homeostasis, respectively. However, the molecular cues that confer their diverse cellular localizations remain largely unknown.\r\n* In this study, we systematically swapped the domains between ER‐ and PM‐localized PIN proteins, as well as between apical and basal PM‐localized PINs from Arabidopsis thaliana , to shed light on why PIN family members with similar topological structures reside at different membrane compartments within cells.\r\n* Our results show that not only do the N‐ and C‐terminal transmembrane domains (TMDs) and central hydrophilic loop contribute to their differential subcellular localizations and cellular polarity, but that the pairwise‐matched N‐ and C‐terminal TMDs resulting from intramolecular domain–domain coevolution are also crucial for their divergent patterns of localization.\r\n* These findings illustrate the complexity of the evolutionary path of PIN proteins in acquiring their plethora of developmental functions and adaptive growth in plants."}],"quality_controlled":"1","volume":227,"language":[{"iso":"eng"}],"corr_author":"1","date_created":"2020-04-30T08:43:29Z","external_id":{"pmid":["32350870"],"isi":["000534092400001"]},"department":[{"_id":"JiFr"}],"publication_status":"published","oa":1,"publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646X"]},"pmid":1,"file":[{"file_size":3643395,"file_id":"8799","date_created":"2020-11-24T12:19:38Z","creator":"dernst","file_name":"2020_09_NewPhytologist_Zhang.pdf","date_updated":"2020-11-24T12:19:38Z","checksum":"8e8150dbbba8cb65b72f81d1f0864b8b","content_type":"application/pdf","success":1,"relation":"main_file","access_level":"open_access"}],"intvolume":"       227","isi":1,"ec_funded":1,"scopus_import":"1","author":[{"orcid":"0000-0003-2627-6956","first_name":"Yuzhou","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87","full_name":"Zhang, Yuzhou","last_name":"Zhang"},{"full_name":"Hartinger, Corinna","last_name":"Hartinger","first_name":"Corinna","id":"AEFB2266-8ABF-11EA-AA39-812C3623CBE4","orcid":"0000-0003-1618-2737"},{"first_name":"Xiaojuan","full_name":"Wang, Xiaojuan","last_name":"Wang"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří"}],"file_date_updated":"2020-11-24T12:19:38Z","publication":"New Phytologist","citation":{"ista":"Zhang Y, Hartinger C, Wang X, Friml J. 2020. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. New Phytologist. 227(5), 1406–1416.","chicago":"Zhang, Yuzhou, Corinna Hartinger, Xiaojuan Wang, and Jiří Friml. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>. Wiley, 2020. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>.","apa":"Zhang, Y., Hartinger, C., Wang, X., &#38; Friml, J. (2020). Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>","ama":"Zhang Y, Hartinger C, Wang X, Friml J. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. 2020;227(5):1406-1416. doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>","ieee":"Y. Zhang, C. Hartinger, X. Wang, and J. Friml, “Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters,” <i>New Phytologist</i>, vol. 227, no. 5. Wiley, pp. 1406–1416, 2020.","short":"Y. Zhang, C. Hartinger, X. Wang, J. Friml, New Phytologist 227 (2020) 1406–1416.","mla":"Zhang, Yuzhou, et al. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>, vol. 227, no. 5, Wiley, 2020, pp. 1406–16, doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>."},"article_processing_charge":"Yes (via OA deal)","month":"09","title":"Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters","_id":"7697","article_type":"original","doi":"10.1111/nph.16629","ddc":["580"],"issue":"5","day":"01","type":"journal_article","publisher":"Wiley","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","page":"1406-1416","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_updated":"2025-04-14T07:45:03Z","year":"2020","oa_version":"Published Version","date_published":"2020-09-01T00:00:00Z","has_accepted_license":"1","project":[{"call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985"},{"call_identifier":"FWF","name":"Molecular mechanisms of endocytic cargo recognition in plants","_id":"26538374-B435-11E9-9278-68D0E5697425","grant_number":"I03630"},{"name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425"}]},{"status":"public","type":"journal_article","day":"20","publisher":"Springer Nature","date_published":"2020-03-20T00:00:00Z","date_updated":"2024-10-15T12:43:32Z","year":"2020","oa_version":"Published Version","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","extern":"1","_id":"7707","month":"03","title":"Quantification of the overall contribution of gene-environment interaction for obesity-related traits","article_processing_charge":"No","citation":{"mla":"Sulc, Jonathan, et al. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>, vol. 11, 1385, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>.","short":"J. Sulc, N. Mounier, F. Günther, T. Winkler, A.R. Wood, T.M. Frayling, I.M. Heid, M.R. Robinson, Z. Kutalik, Nature Communications 11 (2020).","ieee":"J. Sulc <i>et al.</i>, “Quantification of the overall contribution of gene-environment interaction for obesity-related traits,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ama":"Sulc J, Mounier N, Günther F, et al. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>","apa":"Sulc, J., Mounier, N., Günther, F., Winkler, T., Wood, A. R., Frayling, T. M., … Kutalik, Z. (2020). Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>","chicago":"Sulc, Jonathan, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R. Wood, Timothy M. Frayling, Iris M. Heid, Matthew Richard Robinson, and Zoltán Kutalik. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>.","ista":"Sulc J, Mounier N, Günther F, Winkler T, Wood AR, Frayling TM, Heid IM, Robinson MR, Kutalik Z. 2020. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. Nature Communications. 11, 1385."},"OA_type":"gold","article_type":"original","OA_place":"publisher","doi":"10.1038/s41467-020-15107-0","DOAJ_listed":"1","publication_identifier":{"issn":["2041-1723"]},"oa":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-020-15107-0","open_access":"1"}],"author":[{"full_name":"Sulc, Jonathan","last_name":"Sulc","first_name":"Jonathan"},{"first_name":"Ninon","last_name":"Mounier","full_name":"Mounier, Ninon"},{"last_name":"Günther","full_name":"Günther, Felix","first_name":"Felix"},{"full_name":"Winkler, Thomas","last_name":"Winkler","first_name":"Thomas"},{"first_name":"Andrew R.","last_name":"Wood","full_name":"Wood, Andrew R."},{"first_name":"Timothy M.","last_name":"Frayling","full_name":"Frayling, Timothy M."},{"first_name":"Iris M.","last_name":"Heid","full_name":"Heid, Iris M."},{"first_name":"Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","full_name":"Robinson, Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813"},{"last_name":"Kutalik","full_name":"Kutalik, Zoltán","first_name":"Zoltán"}],"publication":"Nature Communications","intvolume":"        11","volume":11,"quality_controlled":"1","article_number":"1385","abstract":[{"lang":"eng","text":"The growing sample size of genome-wide association studies has facilitated the discovery of gene-environment interactions (GxE). Here we propose a maximum likelihood method to estimate the contribution of GxE to continuous traits taking into account all interacting environmental variables, without the need to measure any. Extensive simulations demonstrate that our method provides unbiased interaction estimates and excellent coverage. We also offer strategies to distinguish specific GxE from general scale effects. Applying our method to 32 traits in the UK Biobank reveals that while the genetic risk score (GRS) of 376 variants explains 5.2% of body mass index (BMI) variance, GRSxE explains an additional 1.9%. Nevertheless, this interaction holds for any variable with identical correlation to BMI as the GRS, hence may not be GRS-specific. Still, we observe that the global contribution of specific GRSxE to complex traits is substantial for nine obesity-related measures (including leg impedance and trunk fat-free mass)."}],"publication_status":"published","date_created":"2020-04-30T10:39:33Z","language":[{"iso":"eng"}]},{"quality_controlled":"1","volume":5,"abstract":[{"text":"We conducted DNA methylation association analyses using Illumina 450K data from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case–control cohort (782 cases and 613 controls). Analyses used mixed linear models as implemented in the OSCA software. We found a significantly higher proportion of neutrophils in cases compared to controls which replicated in an independent cohort from the Netherlands (1159 cases and 637 controls). The OSCA MOMENT linear mixed model has been shown in simulations to best account for confounders. When combined in a methylation profile score, the 25 most-associated probes identified by MOMENT significantly classified case–control status in the Netherlands sample (area under the curve, AUC = 0.65, CI95% = [0.62–0.68], p = 8.3 × 10−22). The maximum AUC achieved was 0.69 (CI95% = [0.66–0.71], p = 4.3 × 10−34) when cell-type proportion was included in the predictor.","lang":"eng"}],"article_number":"10","publication_status":"published","language":[{"iso":"eng"}],"date_created":"2020-04-30T10:39:54Z","publication_identifier":{"issn":["2056-7944"]},"oa":1,"DOAJ_listed":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41525-020-0118-3"}],"intvolume":"         5","publication":"npj Genomic Medicine","author":[{"first_name":"Marta F.","last_name":"Nabais","full_name":"Nabais, Marta F."},{"first_name":"Tian","full_name":"Lin, Tian","last_name":"Lin"},{"first_name":"Beben","last_name":"Benyamin","full_name":"Benyamin, Beben"},{"last_name":"Williams","full_name":"Williams, Kelly L.","first_name":"Kelly L."},{"first_name":"Fleur C.","full_name":"Garton, Fleur C.","last_name":"Garton"},{"first_name":"Anna A. E.","last_name":"Vinkhuyzen","full_name":"Vinkhuyzen, Anna A. E."},{"first_name":"Futao","full_name":"Zhang, Futao","last_name":"Zhang"},{"first_name":"Costanza L.","full_name":"Vallerga, Costanza L.","last_name":"Vallerga"},{"first_name":"Restuadi","last_name":"Restuadi","full_name":"Restuadi, Restuadi"},{"first_name":"Anna","full_name":"Freydenzon, Anna","last_name":"Freydenzon"},{"first_name":"Ramona A. J.","full_name":"Zwamborn, Ramona A. J.","last_name":"Zwamborn"},{"last_name":"Hop","full_name":"Hop, Paul J.","first_name":"Paul J."},{"last_name":"Robinson","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","first_name":"Matthew Richard","orcid":"0000-0001-8982-8813"},{"full_name":"Gratten, Jacob","last_name":"Gratten","first_name":"Jacob"},{"full_name":"Visscher, Peter M.","last_name":"Visscher","first_name":"Peter M."},{"first_name":"Eilis","last_name":"Hannon","full_name":"Hannon, Eilis"},{"last_name":"Mill","full_name":"Mill, Jonathan","first_name":"Jonathan"},{"first_name":"Matthew A.","full_name":"Brown, Matthew A.","last_name":"Brown"},{"last_name":"Laing","full_name":"Laing, Nigel G.","first_name":"Nigel G."},{"last_name":"Mather","full_name":"Mather, Karen A.","first_name":"Karen A."},{"first_name":"Perminder S.","last_name":"Sachdev","full_name":"Sachdev, Perminder S."},{"first_name":"Shyuan T.","last_name":"Ngo","full_name":"Ngo, Shyuan T."},{"last_name":"Steyn","full_name":"Steyn, Frederik J.","first_name":"Frederik J."},{"first_name":"Leanne","full_name":"Wallace, Leanne","last_name":"Wallace"},{"first_name":"Anjali K.","full_name":"Henders, Anjali K.","last_name":"Henders"},{"last_name":"Needham","full_name":"Needham, Merrilee","first_name":"Merrilee"},{"first_name":"Jan H.","full_name":"Veldink, Jan H.","last_name":"Veldink"},{"first_name":"Susan","full_name":"Mathers, Susan","last_name":"Mathers"},{"first_name":"Garth","full_name":"Nicholson, Garth","last_name":"Nicholson"},{"first_name":"Dominic B.","last_name":"Rowe","full_name":"Rowe, Dominic B."},{"last_name":"Henderson","full_name":"Henderson, Robert D.","first_name":"Robert D."},{"first_name":"Pamela A.","full_name":"McCombe, Pamela A.","last_name":"McCombe"},{"first_name":"Roger","full_name":"Pamphlett, Roger","last_name":"Pamphlett"},{"first_name":"Jian","full_name":"Yang, Jian","last_name":"Yang"},{"full_name":"Blair, Ian P.","last_name":"Blair","first_name":"Ian P."},{"first_name":"Allan F.","last_name":"McRae","full_name":"McRae, Allan F."},{"first_name":"Naomi R.","last_name":"Wray","full_name":"Wray, Naomi R."}],"title":"Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis","month":"02","_id":"7708","citation":{"mla":"Nabais, Marta F., et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>, vol. 5, 10, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>.","short":"M.F. Nabais, T. Lin, B. Benyamin, K.L. Williams, F.C. Garton, A.A.E. Vinkhuyzen, F. Zhang, C.L. Vallerga, R. Restuadi, A. Freydenzon, R.A.J. Zwamborn, P.J. Hop, M.R. Robinson, J. Gratten, P.M. Visscher, E. Hannon, J. Mill, M.A. Brown, N.G. Laing, K.A. Mather, P.S. Sachdev, S.T. Ngo, F.J. Steyn, L. Wallace, A.K. Henders, M. Needham, J.H. Veldink, S. Mathers, G. Nicholson, D.B. Rowe, R.D. Henderson, P.A. McCombe, R. Pamphlett, J. Yang, I.P. Blair, A.F. McRae, N.R. Wray, Npj Genomic Medicine 5 (2020).","ieee":"M. F. Nabais <i>et al.</i>, “Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis,” <i>npj Genomic Medicine</i>, vol. 5. Springer Nature, 2020.","ama":"Nabais MF, Lin T, Benyamin B, et al. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>npj Genomic Medicine</i>. 2020;5. doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>","apa":"Nabais, M. F., Lin, T., Benyamin, B., Williams, K. L., Garton, F. C., Vinkhuyzen, A. A. E., … Wray, N. R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>Npj Genomic Medicine</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>","chicago":"Nabais, Marta F., Tian Lin, Beben Benyamin, Kelly L. Williams, Fleur C. Garton, Anna A. E. Vinkhuyzen, Futao Zhang, et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>.","ista":"Nabais MF, Lin T, Benyamin B, Williams KL, Garton FC, Vinkhuyzen AAE, Zhang F, Vallerga CL, Restuadi R, Freydenzon A, Zwamborn RAJ, Hop PJ, Robinson MR, Gratten J, Visscher PM, Hannon E, Mill J, Brown MA, Laing NG, Mather KA, Sachdev PS, Ngo ST, Steyn FJ, Wallace L, Henders AK, Needham M, Veldink JH, Mathers S, Nicholson G, Rowe DB, Henderson RD, McCombe PA, Pamphlett R, Yang J, Blair IP, McRae AF, Wray NR. 2020. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine. 5, 10."},"article_processing_charge":"No","OA_place":"publisher","doi":"10.1038/s41525-020-0118-3","article_type":"original","OA_type":"gold","status":"public","day":"27","publisher":"Springer Nature","type":"journal_article","year":"2020","oa_version":"Published Version","date_updated":"2024-10-15T12:41:56Z","date_published":"2020-02-27T00:00:00Z","extern":"1","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0"},{"date_created":"2020-04-30T12:07:55Z","language":[{"iso":"eng"}],"publication_status":"published","article_number":"eabc1939","abstract":[{"text":"Recent advances in synthetic posttranslational protein circuits are substantially impacting the landscape of cellular engineering and offer several advantages compared to traditional gene circuits. However, engineering dynamic phenomena such as oscillations in protein-level circuits remains an outstanding challenge. Few examples of biological posttranslational oscillators are known, necessitating theoretical progress to determine realizable oscillators. We construct mathematical models for two posttranslational oscillators, using few components that interact only through reversible binding and phosphorylation/dephosphorylation reactions. Our designed oscillators rely on the self-assembly of two protein species into multimeric functional enzymes that respectively inhibit and enhance this self-assembly. We limit our analysis to within experimental constraints, finding (i) significant portions of the restricted parameter space yielding oscillations and (ii) that oscillation periods can be tuned by several orders of magnitude using recent advances in computational protein design. Our work paves the way for the rational design and realization of protein-based dynamic systems.","lang":"eng"}],"volume":6,"quality_controlled":"1","publication":"Science Advances","author":[{"first_name":"Ofer","last_name":"Kimchi","full_name":"Kimchi, Ofer"},{"orcid":"0000-0002-1307-5074","full_name":"Goodrich, Carl Peter","last_name":"Goodrich","id":"EB352CD2-F68A-11E9-89C5-A432E6697425","first_name":"Carl Peter"},{"first_name":"Alexis","full_name":"Courbet, Alexis","last_name":"Courbet"},{"first_name":"Agnese I.","full_name":"Curatolo, Agnese I.","last_name":"Curatolo"},{"full_name":"Woodall, Nicholas B.","last_name":"Woodall","first_name":"Nicholas B."},{"first_name":"David","last_name":"Baker","full_name":"Baker, David"},{"first_name":"Michael P.","full_name":"Brenner, Michael P.","last_name":"Brenner"}],"file_date_updated":"2021-04-12T08:33:23Z","intvolume":"         6","DOAJ_listed":"1","file":[{"content_type":"application/pdf","checksum":"eb6d950b6a68ddc4a2fb31ec80a2a1bd","date_updated":"2021-04-12T08:33:23Z","date_created":"2021-04-12T08:33:23Z","file_id":"9320","file_name":"2020_ScienceAdv_Kimchi.pdf","creator":"dernst","file_size":1259758,"relation":"main_file","access_level":"open_access","success":1}],"oa":1,"OA_type":"gold","article_type":"original","OA_place":"publisher","doi":"10.1126/sciadv.abc1939","ddc":["570"],"article_processing_charge":"No","citation":{"ieee":"O. Kimchi <i>et al.</i>, “Self-assembly-based posttranslational protein oscillators,” <i>Science Advances</i>, vol. 6, no. 51. 2020.","short":"O. Kimchi, C.P. Goodrich, A. Courbet, A.I. Curatolo, N.B. Woodall, D. Baker, M.P. Brenner, Science Advances 6 (2020).","mla":"Kimchi, Ofer, et al. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, vol. 6, no. 51, eabc1939, 2020, doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>.","chicago":"Kimchi, Ofer, Carl Peter Goodrich, Alexis Courbet, Agnese I. Curatolo, Nicholas B. Woodall, David Baker, and Michael P. Brenner. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, 2020. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>.","ista":"Kimchi O, Goodrich CP, Courbet A, Curatolo AI, Woodall NB, Baker D, Brenner MP. 2020. Self-assembly-based posttranslational protein oscillators. Science Advances. 6(51), eabc1939.","ama":"Kimchi O, Goodrich CP, Courbet A, et al. Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. 2020;6(51). doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>","apa":"Kimchi, O., Goodrich, C. P., Courbet, A., Curatolo, A. I., Woodall, N. B., Baker, D., &#38; Brenner, M. P. (2020). Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>"},"_id":"7778","month":"12","title":"Self-assembly-based posttranslational protein oscillators","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","extern":"1","has_accepted_license":"1","date_published":"2020-12-16T00:00:00Z","date_updated":"2024-10-15T12:55:13Z","oa_version":"Published Version","year":"2020","issue":"51","type":"journal_article","day":"16","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"oa":1,"publication_identifier":{"eissn":["1879-2650"],"issn":["0005-2728"]},"file":[{"relation":"main_file","access_level":"open_access","file_size":3826792,"date_created":"2020-05-04T12:25:19Z","file_id":"7798","file_name":"2020_BBA_Adjobo_Hermans.pdf","creator":"dernst","date_updated":"2020-07-14T12:48:03Z","checksum":"a9b152381307cf45fe266a8dc5640388","content_type":"application/pdf"}],"pmid":1,"isi":1,"intvolume":"      1861","author":[{"first_name":"Merel J.W.","last_name":"Adjobo-Hermans","full_name":"Adjobo-Hermans, Merel J.W."},{"first_name":"Ria","last_name":"De Haas","full_name":"De Haas, Ria"},{"full_name":"Willems, Peter H.G.M.","last_name":"Willems","first_name":"Peter H.G.M."},{"first_name":"Aleksandra","last_name":"Wojtala","full_name":"Wojtala, Aleksandra"},{"first_name":"Sjenet E.","full_name":"Van Emst-De Vries, Sjenet E.","last_name":"Van Emst-De Vries"},{"full_name":"Wagenaars, Jori A.","last_name":"Wagenaars","first_name":"Jori A."},{"first_name":"Mariel","last_name":"Van Den Brand","full_name":"Van Den Brand, Mariel"},{"full_name":"Rodenburg, Richard J.","last_name":"Rodenburg","first_name":"Richard J."},{"full_name":"Smeitink, Jan A.M.","last_name":"Smeitink","first_name":"Jan A.M."},{"first_name":"Leo G.","full_name":"Nijtmans, Leo G.","last_name":"Nijtmans"},{"orcid":"0000-0002-0977-7989","last_name":"Sazanov","full_name":"Sazanov, Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A"},{"full_name":"Wieckowski, Mariusz R.","last_name":"Wieckowski","first_name":"Mariusz R."},{"first_name":"Werner J.H.","full_name":"Koopman, Werner J.H.","last_name":"Koopman"}],"scopus_import":"1","file_date_updated":"2020-07-14T12:48:03Z","publication":"Biochimica et Biophysica Acta - Bioenergetics","quality_controlled":"1","volume":1861,"abstract":[{"lang":"eng","text":"Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. To study the LS pathomechanism, we here compared OXPHOS proteomes between various Ndufs4−/− mouse tissues. Ndufs4−/− animals displayed significantly lower CI subunit levels in brain/diaphragm relative to other tissues (liver/heart/kidney/skeletal muscle), whereas other OXPHOS subunit levels were not reduced. Absence of NDUFS4 induced near complete absence of the NDUFA12 accessory subunit, a 50% reduction in other CI subunit levels, and an increase in specific CI assembly factors. Among the latter, NDUFAF2 was most highly increased. Regarding NDUFS4, NDUFA12 and NDUFAF2, identical results were obtained in Ndufs4−/− mouse embryonic fibroblasts (MEFs) and NDUFS4-mutated LS patient cells. Ndufs4−/− MEFs contained active CI in situ but blue-native-PAGE highlighted that NDUFAF2 attached to an inactive CI subcomplex (CI-830) and inactive assemblies of higher MW. In NDUFA12-mutated LS patient cells, NDUFA12 absence did not reduce NDUFS4 levels but triggered NDUFAF2 association to active CI. BN-PAGE revealed no such association in LS patient fibroblasts with mutations in other CI subunit-encoding genes where NDUFAF2 was attached to CI-830 (NDUFS1, NDUFV1 mutation) or not detected (NDUFS7 mutation). Supported by enzymological and CI in silico structural analysis, we conclude that absence of NDUFS4 induces near complete absence of NDUFA12 but not vice versa, and that NDUFAF2 stabilizes active CI in Ndufs4−/− mice and LS patient cells, perhaps in concert with mitochondrial inner membrane lipids."}],"article_number":"148213","publication_status":"published","language":[{"iso":"eng"}],"external_id":{"isi":["000540842000012"],"pmid":["32335026"]},"department":[{"_id":"LeSa"}],"date_created":"2020-05-03T22:00:47Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","day":"01","type":"journal_article","publisher":"Elsevier","issue":"8","year":"2020","oa_version":"Published Version","date_updated":"2025-07-10T11:54:47Z","has_accepted_license":"1","date_published":"2020-08-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2","month":"08","_id":"7788","citation":{"ista":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, Wojtala A, Van Emst-De Vries SE, Wagenaars JA, Van Den Brand M, Rodenburg RJ, Smeitink JAM, Nijtmans LG, Sazanov LA, Wieckowski MR, Koopman WJH. 2020. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics. 1861(8), 148213.","chicago":"Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand, et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>.","apa":"Adjobo-Hermans, M. J. W., De Haas, R., Willems, P. H. G. M., Wojtala, A., Van Emst-De Vries, S. E., Wagenaars, J. A., … Koopman, W. J. H. (2020). NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>","ama":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, et al. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. 2020;1861(8). doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>","ieee":"M. J. W. Adjobo-Hermans <i>et al.</i>, “NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2,” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8. Elsevier, 2020.","short":"M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).","mla":"Adjobo-Hermans, Merel J. W., et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8, 148213, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>."},"article_processing_charge":"No","ddc":["570"],"doi":"10.1016/j.bbabio.2020.148213","article_type":"original"},{"quality_controlled":"1","volume":181,"abstract":[{"text":"During embryonic and postnatal development, organs and tissues grow steadily to achieve their final size at the end of puberty. However, little is known about the cellular dynamics that mediate postnatal growth. By combining in vivo clonal lineage tracing, proliferation kinetics, single-cell transcriptomics, andin vitro micro-pattern experiments, we resolved the cellular dynamics taking place during postnatal skin epidermis expansion. Our data revealed that harmonious growth is engineered by a single population of developmental progenitors presenting a fixed fate imbalance of self-renewing divisions with an ever-decreasing proliferation rate. Single-cell RNA sequencing revealed that epidermal developmental progenitors form a more uniform population compared with adult stem and progenitor cells. Finally, we found that the spatial pattern of cell division orientation is dictated locally by the underlying collagen fiber orientation. Our results uncover a simple design principle of organ growth where progenitors and differentiated cells expand in harmony with their surrounding tissues.","lang":"eng"}],"publication_status":"published","language":[{"iso":"eng"}],"department":[{"_id":"EdHa"}],"external_id":{"isi":["000530708400016"],"pmid":["32259486"]},"date_created":"2020-05-03T22:00:48Z","publication_identifier":{"eissn":["1097-4172"],"issn":["0092-8674"]},"oa":1,"file":[{"date_created":"2020-05-04T10:20:55Z","file_id":"7795","file_name":"2020_Cell_Dekoninck.pdf","creator":"dernst","file_size":17992888,"checksum":"e2114902f4e9d75a752e9efb5ae06011","content_type":"application/pdf","date_updated":"2020-07-14T12:48:03Z","relation":"main_file","access_level":"open_access"}],"pmid":1,"intvolume":"       181","isi":1,"scopus_import":"1","author":[{"last_name":"Dekoninck","full_name":"Dekoninck, Sophie","first_name":"Sophie"},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","last_name":"Hannezo","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561"},{"first_name":"Alejandro","full_name":"Sifrim, Alejandro","last_name":"Sifrim"},{"last_name":"Miroshnikova","full_name":"Miroshnikova, Yekaterina A.","first_name":"Yekaterina A."},{"last_name":"Aragona","full_name":"Aragona, Mariaceleste","first_name":"Mariaceleste"},{"last_name":"Malfait","full_name":"Malfait, Milan","first_name":"Milan"},{"first_name":"Souhir","last_name":"Gargouri","full_name":"Gargouri, Souhir"},{"first_name":"Charlotte","full_name":"De Neunheuser, Charlotte","last_name":"De Neunheuser"},{"full_name":"Dubois, Christine","last_name":"Dubois","first_name":"Christine"},{"first_name":"Thierry","last_name":"Voet","full_name":"Voet, Thierry"},{"last_name":"Wickström","full_name":"Wickström, Sara A.","first_name":"Sara A."},{"last_name":"Simons","full_name":"Simons, Benjamin D.","first_name":"Benjamin D."},{"last_name":"Blanpain","full_name":"Blanpain, Cédric","first_name":"Cédric"}],"file_date_updated":"2020-07-14T12:48:03Z","publication":"Cell","title":"Defining the design principles of skin epidermis postnatal growth","month":"04","_id":"7789","citation":{"chicago":"Dekoninck, Sophie, Edouard B Hannezo, Alejandro Sifrim, Yekaterina A. Miroshnikova, Mariaceleste Aragona, Milan Malfait, Souhir Gargouri, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>.","ista":"Dekoninck S, Hannezo EB, Sifrim A, Miroshnikova YA, Aragona M, Malfait M, Gargouri S, De Neunheuser C, Dubois C, Voet T, Wickström SA, Simons BD, Blanpain C. 2020. Defining the design principles of skin epidermis postnatal growth. Cell. 181(3), 604–620.e22.","ama":"Dekoninck S, Hannezo EB, Sifrim A, et al. Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. 2020;181(3):604-620.e22. doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>","apa":"Dekoninck, S., Hannezo, E. B., Sifrim, A., Miroshnikova, Y. A., Aragona, M., Malfait, M., … Blanpain, C. (2020). Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>","ieee":"S. Dekoninck <i>et al.</i>, “Defining the design principles of skin epidermis postnatal growth,” <i>Cell</i>, vol. 181, no. 3. Elsevier, p. 604–620.e22, 2020.","mla":"Dekoninck, Sophie, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>, vol. 181, no. 3, Elsevier, 2020, p. 604–620.e22, doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>.","short":"S. Dekoninck, E.B. Hannezo, A. Sifrim, Y.A. Miroshnikova, M. Aragona, M. Malfait, S. Gargouri, C. De Neunheuser, C. Dubois, T. Voet, S.A. Wickström, B.D. Simons, C. Blanpain, Cell 181 (2020) 604–620.e22."},"article_processing_charge":"No","ddc":["570"],"doi":"10.1016/j.cell.2020.03.015","article_type":"original","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"status":"public","type":"journal_article","publisher":"Elsevier","day":"30","issue":"3","oa_version":"Published Version","year":"2020","date_updated":"2025-07-10T11:54:47Z","date_published":"2020-04-30T00:00:00Z","has_accepted_license":"1","page":"604-620.e22","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"scopus_import":"1","author":[{"first_name":"Javier","full_name":"Taboada-Gutiérrez, Javier","last_name":"Taboada-Gutiérrez"},{"first_name":"Gonzalo","last_name":"Álvarez-Pérez","full_name":"Álvarez-Pérez, Gonzalo"},{"full_name":"Duan, Jiahua","last_name":"Duan","first_name":"Jiahua"},{"last_name":"Ma","full_name":"Ma, Weiliang","first_name":"Weiliang"},{"first_name":"Kyle","full_name":"Crowley, Kyle","last_name":"Crowley"},{"last_name":"Prieto Gonzalez","full_name":"Prieto Gonzalez, Ivan","first_name":"Ivan","id":"2A307FE2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7370-5357"},{"first_name":"Andrei","full_name":"Bylinkin, Andrei","last_name":"Bylinkin"},{"first_name":"Marta","last_name":"Autore","full_name":"Autore, Marta"},{"first_name":"Halyna","full_name":"Volkova, Halyna","last_name":"Volkova"},{"first_name":"Kenta","full_name":"Kimura, Kenta","last_name":"Kimura"},{"last_name":"Kimura","full_name":"Kimura, Tsuyoshi","first_name":"Tsuyoshi"},{"first_name":"M. H.","last_name":"Berger","full_name":"Berger, M. H."},{"full_name":"Li, Shaojuan","last_name":"Li","first_name":"Shaojuan"},{"last_name":"Bao","full_name":"Bao, Qiaoliang","first_name":"Qiaoliang"},{"full_name":"Gao, Xuan P.A.","last_name":"Gao","first_name":"Xuan P.A."},{"first_name":"Ion","last_name":"Errea","full_name":"Errea, Ion"},{"first_name":"Alexey Y.","full_name":"Nikitin, Alexey Y.","last_name":"Nikitin"},{"full_name":"Hillenbrand, Rainer","last_name":"Hillenbrand","first_name":"Rainer"},{"last_name":"Martín-Sánchez","full_name":"Martín-Sánchez, Javier","first_name":"Javier"},{"first_name":"Pablo","last_name":"Alonso-González","full_name":"Alonso-González, Pablo"}],"publication":"Nature Materials","intvolume":"        19","isi":1,"pmid":1,"acknowledgement":"J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa Program from the Government of the Principality of Asturias (nos. PA-18-PF-BP17-126 and PA-20-PF-BP19-053, respectively). J.M.-S. acknowledges finantial support from the Clarín Programme from the Government of the Principality of Asturias and a Marie Curie-COFUND grant (PA-18-ACB17-29) and the Ramón y Cajal Program from the Government of Spain (RYC2018-026196-I). K.C., X.P.A.G., H.V. and M.H.B. acknowledge the Air Force Office of Scientific Research (AFOSR) grant no. FA 9550-18-1-0030 for funding support. I.E. acknowledges financial support from the Spanish Ministry of Economy and Competitiveness (grant no. FIS2016-76617-P). A.Y.N. acknowledges the Spanish Ministry of Science, Innovation and Universities (national project no. MAT2017-88358-C3-3-R) and the Basque Government (grant no. IT1164-19). Q.B. acknowledges the support from Australian Research Council (grant nos. FT150100450, IH150100006 and CE170100039). R.H. acknowledges support from the Spanish Ministry of Economy, Industry, and Competitiveness (national project RTI2018-094830-B-100 and the Project MDM-2016-0618 of the María de Maeztu Units of Excellence Program) and the Basque Goverment (grant no. IT1164-19). P.A.-G. acknowledges support from the European Research Council under starting grant no. 715496, 2DNANOPTICA.","oa":1,"publication_identifier":{"issn":["1476-1122"],"eissn":["1476-4660"]},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2501.08705","open_access":"1"}],"publication_status":"published","date_created":"2020-05-03T22:00:49Z","department":[{"_id":"NanoFab"}],"external_id":{"arxiv":["2501.08705"],"pmid":["32284598"],"isi":["000526218500004"]},"language":[{"iso":"eng"}],"volume":19,"quality_controlled":"1","abstract":[{"text":"Phonon polaritons—light coupled to lattice vibrations—in polar van der Waals crystals are promising candidates for controlling the flow of energy on the nanoscale due to their strong field confinement, anisotropic propagation and ultra-long lifetime in the picosecond range1,2,3,4,5. However, the lack of tunability of their narrow and material-specific spectral range—the Reststrahlen band—severely limits their technological implementation. Here, we demonstrate that intercalation of Na atoms in the van der Waals semiconductor α-V2O5 enables a broad spectral shift of Reststrahlen bands, and that the phonon polaritons excited show ultra-low losses (lifetime of 4 ± 1 ps), similar to phonon polaritons in a non-intercalated crystal (lifetime of 6 ± 1 ps). We expect our intercalation method to be applicable to other van der Waals crystals, opening the door for the use of phonon polaritons in broad spectral bands in the mid-infrared domain.","lang":"eng"}],"date_published":"2020-09-01T00:00:00Z","date_updated":"2025-04-23T14:24:58Z","oa_version":"Preprint","year":"2020","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"964–968","status":"public","day":"01","publisher":"Springer Nature","type":"journal_article","arxiv":1,"article_type":"original","OA_type":"green","doi":"10.1038/s41563-020-0665-0","OA_place":"repository","_id":"7792","month":"09","title":"Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation","article_processing_charge":"No","citation":{"ama":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, et al. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. 2020;19:964–968. doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>","apa":"Taboada-Gutiérrez, J., Álvarez-Pérez, G., Duan, J., Ma, W., Crowley, K., Prieto Gonzalez, I., … Alonso-González, P. (2020). Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>","chicago":"Taboada-Gutiérrez, Javier, Gonzalo Álvarez-Pérez, Jiahua Duan, Weiliang Ma, Kyle Crowley, Ivan Prieto Gonzalez, Andrei Bylinkin, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>.","ista":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, Ma W, Crowley K, Prieto Gonzalez I, Bylinkin A, Autore M, Volkova H, Kimura K, Kimura T, Berger MH, Li S, Bao Q, Gao XPA, Errea I, Nikitin AY, Hillenbrand R, Martín-Sánchez J, Alonso-González P. 2020. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. Nature Materials. 19, 964–968.","mla":"Taboada-Gutiérrez, Javier, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>, vol. 19, Springer Nature, 2020, pp. 964–968, doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>.","short":"J. Taboada-Gutiérrez, G. Álvarez-Pérez, J. Duan, W. Ma, K. Crowley, I. Prieto Gonzalez, A. Bylinkin, M. Autore, H. Volkova, K. Kimura, T. Kimura, M.H. Berger, S. Li, Q. Bao, X.P.A. Gao, I. Errea, A.Y. Nikitin, R. Hillenbrand, J. Martín-Sánchez, P. Alonso-González, Nature Materials 19 (2020) 964–968.","ieee":"J. Taboada-Gutiérrez <i>et al.</i>, “Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation,” <i>Nature Materials</i>, vol. 19. Springer Nature, pp. 964–968, 2020."}}]