[{"project":[{"_id":"2659CC84-B435-11E9-9278-68D0E5697425","grant_number":"793482","call_identifier":"H2020","name":"Ultrastructural analysis of phosphoinositides in nerve terminals: distribution, dynamics and physiological roles in synaptic transmission"},{"call_identifier":"H2020","name":"In situ analysis of single channel subunit composition in neurons: physiological implication in synaptic plasticity and behaviour","grant_number":"694539","_id":"25CA28EA-B435-11E9-9278-68D0E5697425"},{"name":"Optical control of synaptic function via adhesion molecules","call_identifier":"FWF","grant_number":"I03600","_id":"265CB4D0-B435-11E9-9278-68D0E5697425"},{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"}],"ddc":["570"],"intvolume":"        14","publisher":"Frontiers Media","ec_funded":1,"article_processing_charge":"Yes (via OA deal)","volume":14,"type":"journal_article","has_accepted_license":"1","date_created":"2020-04-19T22:00:55Z","citation":{"ieee":"K. Eguchi <i>et al.</i>, “Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions,” <i>Frontiers in Cellular Neuroscience</i>, vol. 14. Frontiers Media, 2020.","ama":"Eguchi K, Velicky P, Saeckl E, et al. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. 2020;14. doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>","short":"K. Eguchi, P. Velicky, E. Saeckl, M. Itakura, Y. Fukazawa, J.G. Danzl, R. Shigemoto, Frontiers in Cellular Neuroscience 14 (2020).","apa":"Eguchi, K., Velicky, P., Saeckl, E., Itakura, M., Fukazawa, Y., Danzl, J. G., &#38; Shigemoto, R. (2020). Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>","mla":"Eguchi, Kohgaku, et al. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>, vol. 14, 63, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>.","chicago":"Eguchi, Kohgaku, Philipp Velicky, Elena Saeckl, Makoto Itakura, Yugo Fukazawa, Johann G Danzl, and Ryuichi Shigemoto. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>.","ista":"Eguchi K, Velicky P, Saeckl E, Itakura M, Fukazawa Y, Danzl JG, Shigemoto R. 2020. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. Frontiers in Cellular Neuroscience. 14, 63."},"publication_status":"published","pmid":1,"language":[{"iso":"eng"}],"isi":1,"external_id":{"pmid":["32265664"],"isi":["000525582200001"]},"oa":1,"article_number":"63","author":[{"id":"2B7846DC-F248-11E8-B48F-1D18A9856A87","first_name":"Kohgaku","full_name":"Eguchi, Kohgaku","last_name":"Eguchi","orcid":"0000-0002-6170-2546"},{"id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2340-7431","last_name":"Velicky","first_name":"Philipp","full_name":"Velicky, Philipp"},{"id":"3C054040-F248-11E8-B48F-1D18A9856A87","last_name":"Hollergschwandtner","first_name":"Elena","full_name":"Hollergschwandtner, Elena"},{"first_name":"Makoto","full_name":"Itakura, Makoto","last_name":"Itakura"},{"first_name":"Yugo","full_name":"Fukazawa, Yugo","last_name":"Fukazawa"},{"last_name":"Danzl","full_name":"Danzl, Johann G","first_name":"Johann G","orcid":"0000-0001-8559-3973","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi"}],"file":[{"file_size":9227283,"file_id":"7668","creator":"dernst","content_type":"application/pdf","date_created":"2020-04-20T10:59:49Z","relation":"main_file","checksum":"1c145123c6f8dc3e2e4bd5a66a1ad60e","date_updated":"2020-07-14T12:48:01Z","access_level":"open_access","file_name":"2020_FrontiersCellularNeurosc_Eguchi.pdf"}],"quality_controlled":"1","article_type":"original","date_updated":"2025-06-12T07:16:39Z","corr_author":"1","month":"03","publication":"Frontiers in Cellular Neuroscience","abstract":[{"lang":"eng","text":"Acute brain slice preparation is a powerful experimental model for investigating the characteristics of synaptic function in the brain. Although brain tissue is usually cut at ice-cold temperature (CT) to facilitate slicing and avoid neuronal damage, exposure to CT causes molecular and architectural changes of synapses. To address these issues, we investigated ultrastructural and electrophysiological features of synapses in mouse acute cerebellar slices prepared at ice-cold and physiological temperature (PT). In the slices prepared at CT, we found significant spine loss and reconstruction, synaptic vesicle rearrangement and decrease in synaptic proteins, all of which were not detected in slices prepared at PT. Consistent with these structural findings, slices prepared at PT showed higher release probability. Furthermore, preparation at PT allows electrophysiological recording immediately after slicing resulting in higher detectability of long-term depression (LTD) after motor learning compared with that at CT. These results indicate substantial advantages of the slice preparation at PT for investigating synaptic functions in different physiological conditions."}],"department":[{"_id":"JoDa"},{"_id":"RySh"}],"license":"https://creativecommons.org/licenses/by/4.0/","_id":"7665","year":"2020","scopus_import":"1","file_date_updated":"2020-07-14T12:48:01Z","publication_identifier":{"issn":["1662-5102"]},"title":"Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"day":"19","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_published":"2020-03-19T00:00:00Z","doi":"10.3389/fncel.2020.00063","oa_version":"Published Version"},{"title":"Tri-partitions and bases of an ordered complex","publication_identifier":{"eissn":["14320444"],"issn":["01795376"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","day":"20","oa_version":"Published Version","doi":"10.1007/s00454-020-00188-x","date_published":"2020-03-20T00:00:00Z","date_updated":"2025-04-14T07:48:36Z","quality_controlled":"1","article_type":"original","file":[{"access_level":"open_access","date_updated":"2020-11-20T13:22:21Z","file_name":"2020_DiscreteCompGeo_Edelsbrunner.pdf","file_size":701673,"content_type":"application/pdf","file_id":"8786","creator":"dernst","success":1,"date_created":"2020-11-20T13:22:21Z","relation":"main_file","checksum":"f8cc96e497f00c38340b5dafe0cb91d7"}],"author":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","full_name":"Edelsbrunner, Herbert","first_name":"Herbert","last_name":"Edelsbrunner","orcid":"0000-0002-9823-6833"},{"id":"4D4AA390-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4672-8297","full_name":"Ölsböck, Katharina","first_name":"Katharina","last_name":"Ölsböck"}],"corr_author":"1","department":[{"_id":"HeEd"}],"abstract":[{"lang":"eng","text":"Generalizing the decomposition of a connected planar graph into a tree and a dual tree, we prove a combinatorial analog of the classic Helmholtz–Hodge decomposition of a smooth vector field. Specifically, we show that for every polyhedral complex, K, and every dimension, p, there is a partition of the set of p-cells into a maximal p-tree, a maximal p-cotree, and a collection of p-cells whose cardinality is the p-th reduced Betti number of K. Given an ordering of the p-cells, this tri-partition is unique, and it can be computed by a matrix reduction algorithm that also constructs canonical bases of cycle and boundary groups."}],"publication":"Discrete and Computational Geometry","month":"03","file_date_updated":"2020-11-20T13:22:21Z","scopus_import":"1","year":"2020","_id":"7666","citation":{"ista":"Edelsbrunner H, Ölsböck K. 2020. Tri-partitions and bases of an ordered complex. Discrete and Computational Geometry. 64, 759–775.","apa":"Edelsbrunner, H., &#38; Ölsböck, K. (2020). Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>","chicago":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>.","mla":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>, vol. 64, Springer Nature, 2020, pp. 759–75, doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>.","short":"H. Edelsbrunner, K. Ölsböck, Discrete and Computational Geometry 64 (2020) 759–775.","ama":"Edelsbrunner H, Ölsböck K. Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. 2020;64:759-775. doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>","ieee":"H. Edelsbrunner and K. Ölsböck, “Tri-partitions and bases of an ordered complex,” <i>Discrete and Computational Geometry</i>, vol. 64. Springer Nature, pp. 759–775, 2020."},"language":[{"iso":"eng"}],"publication_status":"published","page":"759-775","external_id":{"isi":["000520918800001"]},"oa":1,"isi":1,"intvolume":"        64","project":[{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"},{"call_identifier":"H2020","name":"Alpha Shape Theory Extended","grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425"},{"_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35"}],"ddc":["510"],"acknowledgement":"This project has received funding from the European Research Council under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 78818 Alpha). It is also partially supported by the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant No. I02979-N35 of the Austrian Science Fund (FWF).","type":"journal_article","ec_funded":1,"volume":64,"article_processing_charge":"Yes (via OA deal)","publisher":"Springer Nature","date_created":"2020-04-19T22:00:56Z","has_accepted_license":"1"},{"oa_version":"Published Version","doi":"10.1016/j.electacta.2020.137175","date_published":"2020-12-01T00:00:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","day":"01","issue":"12","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"title":"Surface and catalyst driven singlet oxygen formation in Li-O2 cells","file_date_updated":"2020-10-01T13:20:45Z","scopus_import":"1","year":"2020","_id":"7672","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","department":[{"_id":"StFr"}],"abstract":[{"lang":"eng","text":"Large overpotentials upon discharge and charge of Li-O2 cells have motivated extensive research into heterogeneous solid electrocatalysts or non-carbon electrodes with the aim to improve rate capability, round-trip efficiency and cycle life. These features are equally governed by parasitic reactions, which are now recognized to be caused by the highly reactive singlet oxygen (1O2). However, the link between the presence of electrocatalysts and 1O2 formation in metal-O2 cells is unknown. Here, we show that, compared to pristine carbon black electrodes, a representative selection of electrocatalysts or non-carbon electrodes (noble metal, transition metal compounds) may both slightly reduce or severely increase the 1O2 formation. The individual reaction steps, where the surfaces impact the 1O2 yield are deciphered, showing that 1O2 yield from superoxide disproportionation as well as the decomposition of trace H2O2 are sensitive to catalysts. Transition metal compounds in general are prone to increase 1O2."}],"publication":"Electrochimica Acta","month":"12","corr_author":"1","date_updated":"2024-10-09T20:59:27Z","quality_controlled":"1","article_type":"original","file":[{"date_created":"2020-10-01T13:20:45Z","relation":"main_file","checksum":"1ab1aa2024d431e2a089ea336bc08298","success":1,"file_size":1404030,"content_type":"application/pdf","file_id":"8593","creator":"dernst","file_name":"2020_ElectrochimicaActa_Samojlov.pdf","date_updated":"2020-10-01T13:20:45Z","access_level":"open_access"}],"author":[{"last_name":"Samojlov","first_name":"Aleksej","full_name":"Samojlov, Aleksej"},{"full_name":"Schuster, David","first_name":"David","last_name":"Schuster"},{"first_name":"Jürgen","full_name":"Kahr, Jürgen","last_name":"Kahr"},{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander","first_name":"Stefan Alexander","last_name":"Freunberger","orcid":"0000-0003-2902-5319"}],"article_number":"137175","external_id":{"isi":["000582869700060"]},"oa":1,"isi":1,"publication_status":"published","language":[{"iso":"eng"}],"citation":{"mla":"Samojlov, Aleksej, et al. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>, vol. 362, no. 12, 137175, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>.","apa":"Samojlov, A., Schuster, D., Kahr, J., &#38; Freunberger, S. A. (2020). Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>","chicago":"Samojlov, Aleksej, David Schuster, Jürgen Kahr, and Stefan Alexander Freunberger. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>.","ista":"Samojlov A, Schuster D, Kahr J, Freunberger SA. 2020. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. Electrochimica Acta. 362(12), 137175.","ieee":"A. Samojlov, D. Schuster, J. Kahr, and S. A. Freunberger, “Surface and catalyst driven singlet oxygen formation in Li-O2 cells,” <i>Electrochimica Acta</i>, vol. 362, no. 12. Elsevier, 2020.","ama":"Samojlov A, Schuster D, Kahr J, Freunberger SA. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. 2020;362(12). doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>","short":"A. Samojlov, D. Schuster, J. Kahr, S.A. Freunberger, Electrochimica Acta 362 (2020)."},"has_accepted_license":"1","date_created":"2020-04-20T19:29:31Z","acknowledgement":"S.A.F. thanks the International Society of Electrochemistry for awarding the Tajima Prize 2019 “in recognition of outstanding re- searches on Li-Air batteries by the use of a range of in-situ elec- trochemical methods to achieve comprehensive understanding of the reactions taking place at the oxygen electrode”. This article is dedicated to the special issue of Electrochmica Acta associated with the awarding conference. S.A.F. is indebted to and the Austrian Federal Ministry of Science, Research and Economy and the Austrian Research Promotion Agency (grant No. 845364 ) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 636069). The authors thank J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH and G. Strohmeier for help with HPLC measurements, S. Eder for cyclic voltammetry measurements, and C. Slugovc for discussions and continuous support. We thank S. Borisov for access and advice with fluorescence measurements. We thank EL-Cell GmbH, Hamburg, Germany for providing the PAT-Cell-Press electrochemical cell.","type":"journal_article","volume":362,"article_processing_charge":"Yes (via OA deal)","publisher":"Elsevier","intvolume":"       362","ddc":["540"]},{"oa_version":"Published Version","date_published":"2020-04-15T00:00:00Z","doi":"10.1007/s00029-020-00553-x","day":"15","status":"public","user_id":"9947682f-b9fa-11ee-9c4a-b3ffaafe6614","issue":"2","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces","publication_identifier":{"issn":["1022-1824"],"eissn":["1420-9020"]},"year":"2020","file_date_updated":"2020-07-14T12:48:02Z","scopus_import":"1","_id":"7683","department":[{"_id":"TaHa"}],"month":"04","publication":"Selecta Mathematica, New Series","abstract":[{"text":"For any free oriented Borel–Moore homology theory A, we construct an associative product on the A-theory of the stack of Higgs torsion sheaves over a projective curve C. We show that the resulting algebra AHa0C admits a natural shuffle presentation, and prove it is faithful when A is replaced with usual Borel–Moore homology groups. We also introduce moduli spaces of stable triples, heavily inspired by Nakajima quiver varieties, whose A-theory admits an AHa0C-action. These triples can be interpreted as certain sheaves on PC(ωC⊕OC). In particular, we obtain an action of AHa0C on the cohomology of Hilbert schemes of points on T∗C.","lang":"eng"}],"corr_author":"1","date_updated":"2025-05-20T10:38:32Z","author":[{"id":"3E7C5304-F248-11E8-B48F-1D18A9856A87","full_name":"Minets, Sasha","first_name":"Sasha","last_name":"Minets","orcid":"0000-0003-3883-1806"}],"file":[{"file_name":"2020_SelectaMathematica_Minets.pdf","access_level":"open_access","date_updated":"2020-07-14T12:48:02Z","checksum":"2368c4662629b4759295eb365323b2ad","date_created":"2020-04-28T10:57:58Z","relation":"main_file","content_type":"application/pdf","file_id":"7690","creator":"dernst","file_size":792469}],"quality_controlled":"1","article_type":"original","oa":1,"external_id":{"arxiv":["1801.01429"],"isi":["000526036400001"]},"article_number":"30","isi":1,"language":[{"iso":"eng"}],"publication_status":"published","citation":{"ista":"Minets S. 2020. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. Selecta Mathematica, New Series. 26(2), 30.","apa":"Minets, S. (2020). Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>","mla":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2, 30, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>.","chicago":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>.","short":"S. Minets, Selecta Mathematica, New Series 26 (2020).","ama":"Minets S. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. 2020;26(2). doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>","ieee":"S. Minets, “Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces,” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2. Springer Nature, 2020."},"arxiv":1,"date_created":"2020-04-26T22:00:44Z","has_accepted_license":"1","volume":26,"publisher":"Springer Nature","article_processing_charge":"Yes (via OA deal)","type":"journal_article","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"ddc":["510"],"intvolume":"        26"},{"_id":"7686","scopus_import":"1","year":"2020","abstract":[{"lang":"eng","text":"The agricultural green revolution spectacularly enhanced crop yield and lodging resistance with modified DELLA-mediated gibberellin signaling. However, this was achieved at the expense of reduced nitrogen-use efficiency (NUE). Recently, Wu et al. revealed novel gibberellin signaling that provides a blueprint for improving tillering and NUE in Green Revolution varieties (GRVs). "}],"publication":"Trends in Plant Science","month":"06","department":[{"_id":"JiFr"}],"quality_controlled":"1","article_type":"original","author":[{"full_name":"Xue, Huidan","first_name":"Huidan","last_name":"Xue"},{"orcid":"0000-0003-2627-6956","first_name":"Yuzhou","full_name":"Zhang, Yuzhou","last_name":"Zhang","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Xiao","first_name":"Guanghui","full_name":"Xiao, Guanghui"}],"date_updated":"2025-06-25T10:59:39Z","doi":"10.1016/j.tplants.2020.04.001","date_published":"2020-06-01T00:00:00Z","oa_version":"None","issue":"6","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","publication_identifier":{"issn":["1360-1385"]},"title":"Neo-gibberellin signaling: Guiding the next generation of the green revolution","date_created":"2020-04-26T22:00:46Z","type":"journal_article","article_processing_charge":"No","publisher":"Elsevier","volume":25,"intvolume":"        25","isi":1,"external_id":{"pmid":["32407691"],"isi":["000533518400003"]},"page":"520-522","publication_status":"published","pmid":1,"language":[{"iso":"eng"}],"citation":{"short":"H. Xue, Y. Zhang, G. Xiao, Trends in Plant Science 25 (2020) 520–522.","ama":"Xue H, Zhang Y, Xiao G. Neo-gibberellin signaling: Guiding the next generation of the green revolution. <i>Trends in Plant Science</i>. 2020;25(6):520-522. doi:<a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">10.1016/j.tplants.2020.04.001</a>","ieee":"H. Xue, Y. Zhang, and G. Xiao, “Neo-gibberellin signaling: Guiding the next generation of the green revolution,” <i>Trends in Plant Science</i>, vol. 25, no. 6. Elsevier, pp. 520–522, 2020.","ista":"Xue H, Zhang Y, Xiao G. 2020. Neo-gibberellin signaling: Guiding the next generation of the green revolution. Trends in Plant Science. 25(6), 520–522.","apa":"Xue, H., Zhang, Y., &#38; Xiao, G. (2020). Neo-gibberellin signaling: Guiding the next generation of the green revolution. <i>Trends in Plant Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">https://doi.org/10.1016/j.tplants.2020.04.001</a>","mla":"Xue, Huidan, et al. “Neo-Gibberellin Signaling: Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>, vol. 25, no. 6, Elsevier, 2020, pp. 520–22, doi:<a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">10.1016/j.tplants.2020.04.001</a>.","chicago":"Xue, Huidan, Yuzhou Zhang, and Guanghui Xiao. “Neo-Gibberellin Signaling: Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.tplants.2020.04.001\">https://doi.org/10.1016/j.tplants.2020.04.001</a>."}},{"contributor":[{"first_name":"Georgios","last_name":"Katsaros","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","contributor_type":"contact_person"}],"oa":1,"citation":{"short":"G. Katsaros, (2020).","ama":"Katsaros G. Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>","ieee":"G. Katsaros, “Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots.’” Institute of Science and Technology Austria, 2020.","ista":"Katsaros G. 2020. Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","apa":"Katsaros, G. (2020). Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>","mla":"Katsaros, Georgios. <i>Supplementary Data for “Zero Field Splitting of Heavy-Hole States in Quantum Dots.”</i> Institute of Science and Technology Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","chicago":"Katsaros, Georgios. “Supplementary Data for ‘Zero Field Splitting of Heavy-Hole States in Quantum Dots.’” Institute of Science and Technology Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>."},"publisher":"Institute of Science and Technology Austria","ec_funded":1,"article_processing_charge":"No","type":"research_data","has_accepted_license":"1","date_created":"2020-05-01T15:14:46Z","ddc":["530"],"project":[{"_id":"237E5020-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020","name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS","grant_number":"862046"},{"call_identifier":"FWF","name":"Towards scalable hut wire quantum devices","grant_number":"P32235","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E"}],"day":"01","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2020-05-01T00:00:00Z","doi":"10.15479/AT:ISTA:7689","oa_version":"Published Version","title":"Supplementary data for \"Zero field splitting of heavy-hole states in quantum dots\"","tmp":{"legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","name":"Creative Commons Public Domain Dedication (CC0 1.0)","short":"CC0 (1.0)","image":"/images/cc_0.png"},"month":"05","abstract":[{"text":"These are the supplementary research data to the publication \"Zero field splitting of heavy-hole states in quantum dots\". All matrix files have the same format. Within each column the bias voltage is changed. Each column corresponds to either a different gate voltage or magnetic field. The voltage values are given in mV, the current values in pA. Find a specific description in the included Readme file.\r\n","lang":"eng"}],"department":[{"_id":"GeKa"}],"related_material":{"record":[{"id":"8203","status":"public","relation":"used_in_publication"}]},"license":"https://creativecommons.org/publicdomain/zero/1.0/","_id":"7689","year":"2020","file_date_updated":"2020-07-14T12:48:02Z","author":[{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","last_name":"Katsaros","first_name":"Georgios","full_name":"Katsaros, Georgios","orcid":"0000-0001-8342-202X"}],"file":[{"date_updated":"2020-07-14T12:48:02Z","access_level":"open_access","file_name":"DOI_ZeroFieldSplitting.zip","file_size":5514403,"file_id":"7786","creator":"gkatsaro","content_type":"application/x-zip-compressed","date_created":"2020-05-01T15:13:28Z","relation":"main_file","checksum":"d23c0cb9e2d19e14e2f902b88b97c05d"}],"date_updated":"2025-04-15T08:39:16Z","corr_author":"1"},{"title":"High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits","publication_identifier":{"eissn":["1532-2548"],"issn":["0032-0889"]},"oa_version":"Preprint","date_published":"2020-07-01T00:00:00Z","doi":"10.1104/pp.20.00178","day":"01","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","issue":"3","date_updated":"2025-04-15T07:32:09Z","author":[{"full_name":"Wang, J","first_name":"J","last_name":"Wang"},{"last_name":"Mylle","first_name":"E","full_name":"Mylle, E"},{"orcid":"0000-0002-2739-8843","last_name":"Johnson","first_name":"Alexander J","full_name":"Johnson, Alexander J","id":"46A62C3A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Besbrugge","full_name":"Besbrugge, N","first_name":"N"},{"last_name":"De Jaeger","first_name":"G","full_name":"De Jaeger, G"},{"last_name":"Friml","full_name":"Friml, Jiří","first_name":"Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Pleskot","first_name":"R","full_name":"Pleskot, R"},{"full_name":"van Damme, D","first_name":"D","last_name":"van Damme"}],"article_type":"original","quality_controlled":"1","year":"2020","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2020.02.13.948109"}],"scopus_import":"1","_id":"7695","department":[{"_id":"JiFr"}],"month":"07","publication":"Plant Physiology","abstract":[{"lang":"eng","text":"The TPLATE complex (TPC) is a key endocytic adaptor protein complex in plants. TPC in Arabidopsis (Arabidopsis thaliana) contains six evolutionarily conserved subunits and two plant-specific subunits, AtEH1/Pan1 and AtEH2/Pan1, although cytoplasmic proteins are not associated with the hexameric subcomplex in the cytoplasm. To investigate the dynamic assembly of the octameric TPC at the plasma membrane (PM), we performed state-of-the-art dual-color live cell imaging at physiological and lowered temperatures. Lowering the temperature slowed down endocytosis, thereby enhancing the temporal resolution of the differential recruitment of endocytic components. Under both normal and lowered temperature conditions, the core TPC subunit TPLATE and the AtEH/Pan1 proteins exhibited simultaneous recruitment at the PM. These results, together with co-localization analysis of different TPC subunits, allow us to conclude that TPC in plant cells is not recruited to the PM sequentially but as an octameric complex."}],"publication_status":"published","pmid":1,"language":[{"iso":"eng"}],"citation":{"ista":"Wang J, Mylle E, Johnson AJ, Besbrugge N, De Jaeger G, Friml J, Pleskot R, van Damme D. 2020. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. Plant Physiology. 183(3), 986–997.","apa":"Wang, J., Mylle, E., Johnson, A. J., Besbrugge, N., De Jaeger, G., Friml, J., … van Damme, D. (2020). High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>","chicago":"Wang, J, E Mylle, Alexander J Johnson, N Besbrugge, G De Jaeger, Jiří Friml, R Pleskot, and D van Damme. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>. American Society of Plant Biologists, 2020. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>.","mla":"Wang, J., et al. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>, vol. 183, no. 3, American Society of Plant Biologists, 2020, pp. 986–97, doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>.","ieee":"J. Wang <i>et al.</i>, “High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits,” <i>Plant Physiology</i>, vol. 183, no. 3. American Society of Plant Biologists, pp. 986–997, 2020.","short":"J. Wang, E. Mylle, A.J. Johnson, N. Besbrugge, G. De Jaeger, J. Friml, R. Pleskot, D. van Damme, Plant Physiology 183 (2020) 986–997.","ama":"Wang J, Mylle E, Johnson AJ, et al. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. 2020;183(3):986-997. doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>"},"external_id":{"isi":["000550682000018"],"pmid":["32321842"]},"oa":1,"isi":1,"page":"986-997","project":[{"_id":"26538374-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Molecular mechanisms of endocytic cargo recognition in plants","grant_number":"I03630"}],"intvolume":"       183","date_created":"2020-04-29T15:23:00Z","article_processing_charge":"No","type":"journal_article","publisher":"American Society of Plant Biologists","volume":183},{"pmid":1,"publication_status":"published","language":[{"iso":"eng"}],"citation":{"chicago":"Zhang, Yuzhou, Corinna Hartinger, Xiaojuan Wang, and Jiří Friml. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>. Wiley, 2020. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>.","apa":"Zhang, Y., Hartinger, C., Wang, X., &#38; Friml, J. (2020). Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>","mla":"Zhang, Yuzhou, et al. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>, vol. 227, no. 5, Wiley, 2020, pp. 1406–16, doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>.","ista":"Zhang Y, Hartinger C, Wang X, Friml J. 2020. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. New Phytologist. 227(5), 1406–1416.","ieee":"Y. Zhang, C. Hartinger, X. Wang, and J. Friml, “Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters,” <i>New Phytologist</i>, vol. 227, no. 5. Wiley, pp. 1406–1416, 2020.","ama":"Zhang Y, Hartinger C, Wang X, Friml J. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. 2020;227(5):1406-1416. doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>","short":"Y. Zhang, C. Hartinger, X. Wang, J. Friml, New Phytologist 227 (2020) 1406–1416."},"isi":1,"external_id":{"pmid":["32350870"],"isi":["000534092400001"]},"oa":1,"page":"1406-1416","ddc":["580"],"project":[{"name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","grant_number":"742985","_id":"261099A6-B435-11E9-9278-68D0E5697425"},{"name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF","grant_number":"I03630","_id":"26538374-B435-11E9-9278-68D0E5697425"},{"grant_number":"291734","name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"intvolume":"       227","date_created":"2020-04-30T08:43:29Z","has_accepted_license":"1","ec_funded":1,"type":"journal_article","article_processing_charge":"Yes (via OA deal)","publisher":"Wiley","volume":227,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"issn":["0028-646X"],"eissn":["1469-8137"]},"title":"Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters","date_published":"2020-09-01T00:00:00Z","doi":"10.1111/nph.16629","oa_version":"Published Version","issue":"5","day":"01","status":"public","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","corr_author":"1","author":[{"orcid":"0000-0003-2627-6956","last_name":"Zhang","first_name":"Yuzhou","full_name":"Zhang, Yuzhou","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Hartinger, Corinna","first_name":"Corinna","last_name":"Hartinger","orcid":"0000-0003-1618-2737","id":"AEFB2266-8ABF-11EA-AA39-812C3623CBE4"},{"last_name":"Wang","first_name":"Xiaojuan","full_name":"Wang, Xiaojuan"},{"last_name":"Friml","first_name":"Jiří","full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"quality_controlled":"1","file":[{"file_name":"2020_09_NewPhytologist_Zhang.pdf","access_level":"open_access","date_updated":"2020-11-24T12:19:38Z","success":1,"relation":"main_file","date_created":"2020-11-24T12:19:38Z","checksum":"8e8150dbbba8cb65b72f81d1f0864b8b","file_size":3643395,"content_type":"application/pdf","file_id":"8799","creator":"dernst"}],"article_type":"original","date_updated":"2025-04-14T07:45:03Z","_id":"7697","year":"2020","scopus_import":"1","file_date_updated":"2020-11-24T12:19:38Z","publication":"New Phytologist","month":"09","abstract":[{"text":"* Morphogenesis and adaptive tropic growth in plants depend on gradients of the phytohormone auxin, mediated by the membrane‐based PIN‐FORMED (PIN) auxin transporters. PINs localize to a particular side of the plasma membrane (PM) or to the endoplasmic reticulum (ER) to directionally transport auxin and maintain intercellular and intracellular auxin homeostasis, respectively. However, the molecular cues that confer their diverse cellular localizations remain largely unknown.\r\n* In this study, we systematically swapped the domains between ER‐ and PM‐localized PIN proteins, as well as between apical and basal PM‐localized PINs from Arabidopsis thaliana , to shed light on why PIN family members with similar topological structures reside at different membrane compartments within cells.\r\n* Our results show that not only do the N‐ and C‐terminal transmembrane domains (TMDs) and central hydrophilic loop contribute to their differential subcellular localizations and cellular polarity, but that the pairwise‐matched N‐ and C‐terminal TMDs resulting from intramolecular domain–domain coevolution are also crucial for their divergent patterns of localization.\r\n* These findings illustrate the complexity of the evolutionary path of PIN proteins in acquiring their plethora of developmental functions and adaptive growth in plants.","lang":"eng"}],"department":[{"_id":"JiFr"}]},{"author":[{"full_name":"Sulc, Jonathan","first_name":"Jonathan","last_name":"Sulc"},{"last_name":"Mounier","first_name":"Ninon","full_name":"Mounier, Ninon"},{"last_name":"Günther","first_name":"Felix","full_name":"Günther, Felix"},{"last_name":"Winkler","first_name":"Thomas","full_name":"Winkler, Thomas"},{"first_name":"Andrew R.","full_name":"Wood, Andrew R.","last_name":"Wood"},{"full_name":"Frayling, Timothy M.","first_name":"Timothy M.","last_name":"Frayling"},{"first_name":"Iris M.","full_name":"Heid, Iris M.","last_name":"Heid"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","full_name":"Robinson, Matthew Richard","first_name":"Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813"},{"last_name":"Kutalik","full_name":"Kutalik, Zoltán","first_name":"Zoltán"}],"extern":"1","article_type":"original","quality_controlled":"1","date_updated":"2024-10-15T12:43:32Z","publication":"Nature Communications","month":"03","abstract":[{"text":"The growing sample size of genome-wide association studies has facilitated the discovery of gene-environment interactions (GxE). Here we propose a maximum likelihood method to estimate the contribution of GxE to continuous traits taking into account all interacting environmental variables, without the need to measure any. Extensive simulations demonstrate that our method provides unbiased interaction estimates and excellent coverage. We also offer strategies to distinguish specific GxE from general scale effects. Applying our method to 32 traits in the UK Biobank reveals that while the genetic risk score (GRS) of 376 variants explains 5.2% of body mass index (BMI) variance, GRSxE explains an additional 1.9%. Nevertheless, this interaction holds for any variable with identical correlation to BMI as the GRS, hence may not be GRS-specific. Still, we observe that the global contribution of specific GRSxE to complex traits is substantial for nine obesity-related measures (including leg impedance and trunk fat-free mass).","lang":"eng"}],"_id":"7707","OA_place":"publisher","year":"2020","main_file_link":[{"url":"https://doi.org/10.1038/s41467-020-15107-0","open_access":"1"}],"publication_identifier":{"issn":["2041-1723"]},"DOAJ_listed":"1","title":"Quantification of the overall contribution of gene-environment interaction for obesity-related traits","day":"20","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","status":"public","date_published":"2020-03-20T00:00:00Z","doi":"10.1038/s41467-020-15107-0","oa_version":"Published Version","intvolume":"        11","volume":11,"publisher":"Springer Nature","article_processing_charge":"No","type":"journal_article","date_created":"2020-04-30T10:39:33Z","citation":{"ieee":"J. Sulc <i>et al.</i>, “Quantification of the overall contribution of gene-environment interaction for obesity-related traits,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ama":"Sulc J, Mounier N, Günther F, et al. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>","short":"J. Sulc, N. Mounier, F. Günther, T. Winkler, A.R. Wood, T.M. Frayling, I.M. Heid, M.R. Robinson, Z. Kutalik, Nature Communications 11 (2020).","chicago":"Sulc, Jonathan, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R. Wood, Timothy M. Frayling, Iris M. Heid, Matthew Richard Robinson, and Zoltán Kutalik. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>.","mla":"Sulc, Jonathan, et al. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>, vol. 11, 1385, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>.","apa":"Sulc, J., Mounier, N., Günther, F., Winkler, T., Wood, A. R., Frayling, T. M., … Kutalik, Z. (2020). Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>","ista":"Sulc J, Mounier N, Günther F, Winkler T, Wood AR, Frayling TM, Heid IM, Robinson MR, Kutalik Z. 2020. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. Nature Communications. 11, 1385."},"publication_status":"published","language":[{"iso":"eng"}],"OA_type":"gold","oa":1,"article_number":"1385"},{"intvolume":"         5","type":"journal_article","volume":5,"article_processing_charge":"No","publisher":"Springer Nature","date_created":"2020-04-30T10:39:54Z","citation":{"ieee":"M. F. Nabais <i>et al.</i>, “Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis,” <i>npj Genomic Medicine</i>, vol. 5. Springer Nature, 2020.","short":"M.F. Nabais, T. Lin, B. Benyamin, K.L. Williams, F.C. Garton, A.A.E. Vinkhuyzen, F. Zhang, C.L. Vallerga, R. Restuadi, A. Freydenzon, R.A.J. Zwamborn, P.J. Hop, M.R. Robinson, J. Gratten, P.M. Visscher, E. Hannon, J. Mill, M.A. Brown, N.G. Laing, K.A. Mather, P.S. Sachdev, S.T. Ngo, F.J. Steyn, L. Wallace, A.K. Henders, M. Needham, J.H. Veldink, S. Mathers, G. Nicholson, D.B. Rowe, R.D. Henderson, P.A. McCombe, R. Pamphlett, J. Yang, I.P. Blair, A.F. McRae, N.R. Wray, Npj Genomic Medicine 5 (2020).","ama":"Nabais MF, Lin T, Benyamin B, et al. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>npj Genomic Medicine</i>. 2020;5. doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>","ista":"Nabais MF, Lin T, Benyamin B, Williams KL, Garton FC, Vinkhuyzen AAE, Zhang F, Vallerga CL, Restuadi R, Freydenzon A, Zwamborn RAJ, Hop PJ, Robinson MR, Gratten J, Visscher PM, Hannon E, Mill J, Brown MA, Laing NG, Mather KA, Sachdev PS, Ngo ST, Steyn FJ, Wallace L, Henders AK, Needham M, Veldink JH, Mathers S, Nicholson G, Rowe DB, Henderson RD, McCombe PA, Pamphlett R, Yang J, Blair IP, McRae AF, Wray NR. 2020. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine. 5, 10.","apa":"Nabais, M. F., Lin, T., Benyamin, B., Williams, K. L., Garton, F. C., Vinkhuyzen, A. A. E., … Wray, N. R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>Npj Genomic Medicine</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>","chicago":"Nabais, Marta F., Tian Lin, Beben Benyamin, Kelly L. Williams, Fleur C. Garton, Anna A. E. Vinkhuyzen, Futao Zhang, et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>.","mla":"Nabais, Marta F., et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>, vol. 5, 10, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>."},"language":[{"iso":"eng"}],"publication_status":"published","OA_type":"gold","article_number":"10","oa":1,"date_updated":"2024-10-15T12:41:56Z","quality_controlled":"1","article_type":"original","author":[{"last_name":"Nabais","full_name":"Nabais, Marta F.","first_name":"Marta F."},{"full_name":"Lin, Tian","first_name":"Tian","last_name":"Lin"},{"last_name":"Benyamin","full_name":"Benyamin, Beben","first_name":"Beben"},{"last_name":"Williams","full_name":"Williams, Kelly L.","first_name":"Kelly L."},{"first_name":"Fleur C.","full_name":"Garton, Fleur C.","last_name":"Garton"},{"full_name":"Vinkhuyzen, Anna A. E.","first_name":"Anna A. E.","last_name":"Vinkhuyzen"},{"last_name":"Zhang","full_name":"Zhang, Futao","first_name":"Futao"},{"last_name":"Vallerga","first_name":"Costanza L.","full_name":"Vallerga, Costanza L."},{"first_name":"Restuadi","full_name":"Restuadi, Restuadi","last_name":"Restuadi"},{"last_name":"Freydenzon","first_name":"Anna","full_name":"Freydenzon, Anna"},{"first_name":"Ramona A. J.","full_name":"Zwamborn, Ramona A. J.","last_name":"Zwamborn"},{"full_name":"Hop, Paul J.","first_name":"Paul J.","last_name":"Hop"},{"orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","last_name":"Robinson","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"},{"full_name":"Gratten, Jacob","first_name":"Jacob","last_name":"Gratten"},{"last_name":"Visscher","full_name":"Visscher, Peter M.","first_name":"Peter M."},{"first_name":"Eilis","full_name":"Hannon, Eilis","last_name":"Hannon"},{"first_name":"Jonathan","full_name":"Mill, Jonathan","last_name":"Mill"},{"last_name":"Brown","full_name":"Brown, Matthew A.","first_name":"Matthew A."},{"first_name":"Nigel G.","full_name":"Laing, Nigel G.","last_name":"Laing"},{"last_name":"Mather","full_name":"Mather, Karen A.","first_name":"Karen A."},{"full_name":"Sachdev, Perminder S.","first_name":"Perminder S.","last_name":"Sachdev"},{"last_name":"Ngo","full_name":"Ngo, Shyuan T.","first_name":"Shyuan T."},{"last_name":"Steyn","first_name":"Frederik J.","full_name":"Steyn, Frederik J."},{"last_name":"Wallace","full_name":"Wallace, Leanne","first_name":"Leanne"},{"last_name":"Henders","full_name":"Henders, Anjali K.","first_name":"Anjali K."},{"last_name":"Needham","full_name":"Needham, Merrilee","first_name":"Merrilee"},{"first_name":"Jan H.","full_name":"Veldink, Jan H.","last_name":"Veldink"},{"first_name":"Susan","full_name":"Mathers, Susan","last_name":"Mathers"},{"last_name":"Nicholson","first_name":"Garth","full_name":"Nicholson, Garth"},{"last_name":"Rowe","first_name":"Dominic B.","full_name":"Rowe, Dominic B."},{"full_name":"Henderson, Robert D.","first_name":"Robert D.","last_name":"Henderson"},{"first_name":"Pamela A.","full_name":"McCombe, Pamela A.","last_name":"McCombe"},{"last_name":"Pamphlett","full_name":"Pamphlett, Roger","first_name":"Roger"},{"first_name":"Jian","full_name":"Yang, Jian","last_name":"Yang"},{"full_name":"Blair, Ian P.","first_name":"Ian P.","last_name":"Blair"},{"first_name":"Allan F.","full_name":"McRae, Allan F.","last_name":"McRae"},{"last_name":"Wray","full_name":"Wray, Naomi R.","first_name":"Naomi R."}],"extern":"1","abstract":[{"text":"We conducted DNA methylation association analyses using Illumina 450K data from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case–control cohort (782 cases and 613 controls). Analyses used mixed linear models as implemented in the OSCA software. We found a significantly higher proportion of neutrophils in cases compared to controls which replicated in an independent cohort from the Netherlands (1159 cases and 637 controls). The OSCA MOMENT linear mixed model has been shown in simulations to best account for confounders. When combined in a methylation profile score, the 25 most-associated probes identified by MOMENT significantly classified case–control status in the Netherlands sample (area under the curve, AUC = 0.65, CI95% = [0.62–0.68], p = 8.3 × 10−22). The maximum AUC achieved was 0.69 (CI95% = [0.66–0.71], p = 4.3 × 10−34) when cell-type proportion was included in the predictor.","lang":"eng"}],"publication":"npj Genomic Medicine","month":"02","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41525-020-0118-3"}],"year":"2020","_id":"7708","OA_place":"publisher","title":"Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis","DOAJ_listed":"1","publication_identifier":{"issn":["2056-7944"]},"status":"public","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","day":"27","oa_version":"Published Version","doi":"10.1038/s41525-020-0118-3","date_published":"2020-02-27T00:00:00Z"},{"type":"journal_article","article_processing_charge":"No","volume":6,"has_accepted_license":"1","date_created":"2020-04-30T12:07:55Z","ddc":["570"],"intvolume":"         6","OA_type":"gold","oa":1,"article_number":"eabc1939","citation":{"short":"O. Kimchi, C.P. Goodrich, A. Courbet, A.I. Curatolo, N.B. Woodall, D. Baker, M.P. Brenner, Science Advances 6 (2020).","ama":"Kimchi O, Goodrich CP, Courbet A, et al. Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. 2020;6(51). doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>","ieee":"O. Kimchi <i>et al.</i>, “Self-assembly-based posttranslational protein oscillators,” <i>Science Advances</i>, vol. 6, no. 51. 2020.","ista":"Kimchi O, Goodrich CP, Courbet A, Curatolo AI, Woodall NB, Baker D, Brenner MP. 2020. Self-assembly-based posttranslational protein oscillators. Science Advances. 6(51), eabc1939.","mla":"Kimchi, Ofer, et al. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, vol. 6, no. 51, eabc1939, 2020, doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>.","chicago":"Kimchi, Ofer, Carl Peter Goodrich, Alexis Courbet, Agnese I. Curatolo, Nicholas B. Woodall, David Baker, and Michael P. Brenner. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, 2020. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>.","apa":"Kimchi, O., Goodrich, C. P., Courbet, A., Curatolo, A. I., Woodall, N. B., Baker, D., &#38; Brenner, M. P. (2020). Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>"},"publication_status":"published","language":[{"iso":"eng"}],"month":"12","publication":"Science Advances","abstract":[{"text":"Recent advances in synthetic posttranslational protein circuits are substantially impacting the landscape of cellular engineering and offer several advantages compared to traditional gene circuits. However, engineering dynamic phenomena such as oscillations in protein-level circuits remains an outstanding challenge. Few examples of biological posttranslational oscillators are known, necessitating theoretical progress to determine realizable oscillators. We construct mathematical models for two posttranslational oscillators, using few components that interact only through reversible binding and phosphorylation/dephosphorylation reactions. Our designed oscillators rely on the self-assembly of two protein species into multimeric functional enzymes that respectively inhibit and enhance this self-assembly. We limit our analysis to within experimental constraints, finding (i) significant portions of the restricted parameter space yielding oscillations and (ii) that oscillation periods can be tuned by several orders of magnitude using recent advances in computational protein design. Our work paves the way for the rational design and realization of protein-based dynamic systems.","lang":"eng"}],"year":"2020","file_date_updated":"2021-04-12T08:33:23Z","OA_place":"publisher","_id":"7778","date_updated":"2024-10-15T12:55:13Z","author":[{"last_name":"Kimchi","first_name":"Ofer","full_name":"Kimchi, Ofer"},{"full_name":"Goodrich, Carl Peter","first_name":"Carl Peter","last_name":"Goodrich","orcid":"0000-0002-1307-5074","id":"EB352CD2-F68A-11E9-89C5-A432E6697425"},{"first_name":"Alexis","full_name":"Courbet, Alexis","last_name":"Courbet"},{"full_name":"Curatolo, Agnese I.","first_name":"Agnese I.","last_name":"Curatolo"},{"last_name":"Woodall","full_name":"Woodall, Nicholas B.","first_name":"Nicholas B."},{"first_name":"David","full_name":"Baker, David","last_name":"Baker"},{"last_name":"Brenner","full_name":"Brenner, Michael P.","first_name":"Michael P."}],"extern":"1","file":[{"checksum":"eb6d950b6a68ddc4a2fb31ec80a2a1bd","relation":"main_file","date_created":"2021-04-12T08:33:23Z","success":1,"file_id":"9320","creator":"dernst","content_type":"application/pdf","file_size":1259758,"file_name":"2020_ScienceAdv_Kimchi.pdf","date_updated":"2021-04-12T08:33:23Z","access_level":"open_access"}],"quality_controlled":"1","article_type":"original","day":"16","status":"public","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","issue":"51","oa_version":"Published Version","date_published":"2020-12-16T00:00:00Z","doi":"10.1126/sciadv.abc1939","title":"Self-assembly-based posttranslational protein oscillators","DOAJ_listed":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"}},{"article_number":"148213","oa":1,"external_id":{"pmid":["32335026"],"isi":["000540842000012"]},"isi":1,"language":[{"iso":"eng"}],"pmid":1,"publication_status":"published","citation":{"short":"M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).","ama":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, et al. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. 2020;1861(8). doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>","ieee":"M. J. W. Adjobo-Hermans <i>et al.</i>, “NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2,” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8. Elsevier, 2020.","ista":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, Wojtala A, Van Emst-De Vries SE, Wagenaars JA, Van Den Brand M, Rodenburg RJ, Smeitink JAM, Nijtmans LG, Sazanov LA, Wieckowski MR, Koopman WJH. 2020. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics. 1861(8), 148213.","mla":"Adjobo-Hermans, Merel J. W., et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8, 148213, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>.","chicago":"Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand, et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>.","apa":"Adjobo-Hermans, M. J. W., De Haas, R., Willems, P. H. G. M., Wojtala, A., Van Emst-De Vries, S. E., Wagenaars, J. A., … Koopman, W. J. H. (2020). NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>"},"date_created":"2020-05-03T22:00:47Z","has_accepted_license":"1","type":"journal_article","article_processing_charge":"No","publisher":"Elsevier","volume":1861,"intvolume":"      1861","ddc":["570"],"oa_version":"Published Version","doi":"10.1016/j.bbabio.2020.148213","date_published":"2020-08-01T00:00:00Z","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","issue":"8","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2","publication_identifier":{"eissn":["1879-2650"],"issn":["0005-2728"]},"file_date_updated":"2020-07-14T12:48:03Z","scopus_import":"1","year":"2020","_id":"7788","department":[{"_id":"LeSa"}],"abstract":[{"lang":"eng","text":"Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. To study the LS pathomechanism, we here compared OXPHOS proteomes between various Ndufs4−/− mouse tissues. Ndufs4−/− animals displayed significantly lower CI subunit levels in brain/diaphragm relative to other tissues (liver/heart/kidney/skeletal muscle), whereas other OXPHOS subunit levels were not reduced. Absence of NDUFS4 induced near complete absence of the NDUFA12 accessory subunit, a 50% reduction in other CI subunit levels, and an increase in specific CI assembly factors. Among the latter, NDUFAF2 was most highly increased. Regarding NDUFS4, NDUFA12 and NDUFAF2, identical results were obtained in Ndufs4−/− mouse embryonic fibroblasts (MEFs) and NDUFS4-mutated LS patient cells. Ndufs4−/− MEFs contained active CI in situ but blue-native-PAGE highlighted that NDUFAF2 attached to an inactive CI subcomplex (CI-830) and inactive assemblies of higher MW. In NDUFA12-mutated LS patient cells, NDUFA12 absence did not reduce NDUFS4 levels but triggered NDUFAF2 association to active CI. BN-PAGE revealed no such association in LS patient fibroblasts with mutations in other CI subunit-encoding genes where NDUFAF2 was attached to CI-830 (NDUFS1, NDUFV1 mutation) or not detected (NDUFS7 mutation). Supported by enzymological and CI in silico structural analysis, we conclude that absence of NDUFS4 induces near complete absence of NDUFA12 but not vice versa, and that NDUFAF2 stabilizes active CI in Ndufs4−/− mice and LS patient cells, perhaps in concert with mitochondrial inner membrane lipids."}],"month":"08","publication":"Biochimica et Biophysica Acta - Bioenergetics","date_updated":"2025-07-10T11:54:47Z","quality_controlled":"1","article_type":"original","file":[{"file_size":3826792,"file_id":"7798","content_type":"application/pdf","creator":"dernst","date_created":"2020-05-04T12:25:19Z","relation":"main_file","checksum":"a9b152381307cf45fe266a8dc5640388","access_level":"open_access","date_updated":"2020-07-14T12:48:03Z","file_name":"2020_BBA_Adjobo_Hermans.pdf"}],"author":[{"last_name":"Adjobo-Hermans","full_name":"Adjobo-Hermans, Merel J.W.","first_name":"Merel J.W."},{"last_name":"De Haas","first_name":"Ria","full_name":"De Haas, Ria"},{"full_name":"Willems, Peter H.G.M.","first_name":"Peter H.G.M.","last_name":"Willems"},{"first_name":"Aleksandra","full_name":"Wojtala, Aleksandra","last_name":"Wojtala"},{"last_name":"Van Emst-De Vries","full_name":"Van Emst-De Vries, Sjenet E.","first_name":"Sjenet E."},{"last_name":"Wagenaars","full_name":"Wagenaars, Jori A.","first_name":"Jori A."},{"first_name":"Mariel","full_name":"Van Den Brand, Mariel","last_name":"Van Den Brand"},{"full_name":"Rodenburg, Richard J.","first_name":"Richard J.","last_name":"Rodenburg"},{"first_name":"Jan A.M.","full_name":"Smeitink, Jan A.M.","last_name":"Smeitink"},{"last_name":"Nijtmans","full_name":"Nijtmans, Leo G.","first_name":"Leo G."},{"id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A","full_name":"Sazanov, Leonid A","last_name":"Sazanov","orcid":"0000-0002-0977-7989"},{"first_name":"Mariusz R.","full_name":"Wieckowski, Mariusz R.","last_name":"Wieckowski"},{"last_name":"Koopman","full_name":"Koopman, Werner J.H.","first_name":"Werner J.H."}]},{"article_processing_charge":"No","type":"journal_article","volume":181,"publisher":"Elsevier","has_accepted_license":"1","date_created":"2020-05-03T22:00:48Z","intvolume":"       181","ddc":["570"],"page":"604-620.e22","isi":1,"oa":1,"external_id":{"isi":["000530708400016"],"pmid":["32259486"]},"citation":{"chicago":"Dekoninck, Sophie, Edouard B Hannezo, Alejandro Sifrim, Yekaterina A. Miroshnikova, Mariaceleste Aragona, Milan Malfait, Souhir Gargouri, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>.","mla":"Dekoninck, Sophie, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>, vol. 181, no. 3, Elsevier, 2020, p. 604–620.e22, doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>.","apa":"Dekoninck, S., Hannezo, E. B., Sifrim, A., Miroshnikova, Y. A., Aragona, M., Malfait, M., … Blanpain, C. (2020). Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>","ista":"Dekoninck S, Hannezo EB, Sifrim A, Miroshnikova YA, Aragona M, Malfait M, Gargouri S, De Neunheuser C, Dubois C, Voet T, Wickström SA, Simons BD, Blanpain C. 2020. Defining the design principles of skin epidermis postnatal growth. Cell. 181(3), 604–620.e22.","ama":"Dekoninck S, Hannezo EB, Sifrim A, et al. Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. 2020;181(3):604-620.e22. doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>","short":"S. Dekoninck, E.B. Hannezo, A. Sifrim, Y.A. Miroshnikova, M. Aragona, M. Malfait, S. Gargouri, C. De Neunheuser, C. Dubois, T. Voet, S.A. Wickström, B.D. Simons, C. Blanpain, Cell 181 (2020) 604–620.e22.","ieee":"S. Dekoninck <i>et al.</i>, “Defining the design principles of skin epidermis postnatal growth,” <i>Cell</i>, vol. 181, no. 3. Elsevier, p. 604–620.e22, 2020."},"language":[{"iso":"eng"}],"pmid":1,"publication_status":"published","abstract":[{"text":"During embryonic and postnatal development, organs and tissues grow steadily to achieve their final size at the end of puberty. However, little is known about the cellular dynamics that mediate postnatal growth. By combining in vivo clonal lineage tracing, proliferation kinetics, single-cell transcriptomics, andin vitro micro-pattern experiments, we resolved the cellular dynamics taking place during postnatal skin epidermis expansion. Our data revealed that harmonious growth is engineered by a single population of developmental progenitors presenting a fixed fate imbalance of self-renewing divisions with an ever-decreasing proliferation rate. Single-cell RNA sequencing revealed that epidermal developmental progenitors form a more uniform population compared with adult stem and progenitor cells. Finally, we found that the spatial pattern of cell division orientation is dictated locally by the underlying collagen fiber orientation. Our results uncover a simple design principle of organ growth where progenitors and differentiated cells expand in harmony with their surrounding tissues.","lang":"eng"}],"publication":"Cell","month":"04","department":[{"_id":"EdHa"}],"_id":"7789","scopus_import":"1","file_date_updated":"2020-07-14T12:48:03Z","year":"2020","quality_controlled":"1","file":[{"date_updated":"2020-07-14T12:48:03Z","access_level":"open_access","file_name":"2020_Cell_Dekoninck.pdf","creator":"dernst","content_type":"application/pdf","file_id":"7795","file_size":17992888,"checksum":"e2114902f4e9d75a752e9efb5ae06011","relation":"main_file","date_created":"2020-05-04T10:20:55Z"}],"article_type":"original","author":[{"last_name":"Dekoninck","first_name":"Sophie","full_name":"Dekoninck, Sophie"},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo","full_name":"Hannezo, Edouard B","first_name":"Edouard B","orcid":"0000-0001-6005-1561"},{"full_name":"Sifrim, Alejandro","first_name":"Alejandro","last_name":"Sifrim"},{"last_name":"Miroshnikova","first_name":"Yekaterina A.","full_name":"Miroshnikova, Yekaterina A."},{"last_name":"Aragona","first_name":"Mariaceleste","full_name":"Aragona, Mariaceleste"},{"last_name":"Malfait","first_name":"Milan","full_name":"Malfait, Milan"},{"first_name":"Souhir","full_name":"Gargouri, Souhir","last_name":"Gargouri"},{"full_name":"De Neunheuser, Charlotte","first_name":"Charlotte","last_name":"De Neunheuser"},{"first_name":"Christine","full_name":"Dubois, Christine","last_name":"Dubois"},{"last_name":"Voet","first_name":"Thierry","full_name":"Voet, Thierry"},{"first_name":"Sara A.","full_name":"Wickström, Sara A.","last_name":"Wickström"},{"first_name":"Benjamin D.","full_name":"Simons, Benjamin D.","last_name":"Simons"},{"last_name":"Blanpain","first_name":"Cédric","full_name":"Blanpain, Cédric"}],"date_updated":"2025-07-10T11:54:47Z","issue":"3","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"30","doi":"10.1016/j.cell.2020.03.015","date_published":"2020-04-30T00:00:00Z","oa_version":"Published Version","publication_identifier":{"eissn":["1097-4172"],"issn":["0092-8674"]},"title":"Defining the design principles of skin epidermis postnatal growth","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"}},{"publication_identifier":{"issn":["1476-1122"],"eissn":["1476-4660"]},"title":"Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation","doi":"10.1038/s41563-020-0665-0","date_published":"2020-09-01T00:00:00Z","oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","day":"01","article_type":"original","quality_controlled":"1","author":[{"full_name":"Taboada-Gutiérrez, Javier","first_name":"Javier","last_name":"Taboada-Gutiérrez"},{"last_name":"Álvarez-Pérez","first_name":"Gonzalo","full_name":"Álvarez-Pérez, Gonzalo"},{"full_name":"Duan, Jiahua","first_name":"Jiahua","last_name":"Duan"},{"full_name":"Ma, Weiliang","first_name":"Weiliang","last_name":"Ma"},{"full_name":"Crowley, Kyle","first_name":"Kyle","last_name":"Crowley"},{"full_name":"Prieto Gonzalez, Ivan","first_name":"Ivan","last_name":"Prieto Gonzalez","orcid":"0000-0002-7370-5357","id":"2A307FE2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bylinkin, Andrei","first_name":"Andrei","last_name":"Bylinkin"},{"full_name":"Autore, Marta","first_name":"Marta","last_name":"Autore"},{"last_name":"Volkova","full_name":"Volkova, Halyna","first_name":"Halyna"},{"first_name":"Kenta","full_name":"Kimura, Kenta","last_name":"Kimura"},{"full_name":"Kimura, Tsuyoshi","first_name":"Tsuyoshi","last_name":"Kimura"},{"first_name":"M. H.","full_name":"Berger, M. H.","last_name":"Berger"},{"last_name":"Li","full_name":"Li, Shaojuan","first_name":"Shaojuan"},{"last_name":"Bao","full_name":"Bao, Qiaoliang","first_name":"Qiaoliang"},{"last_name":"Gao","first_name":"Xuan P.A.","full_name":"Gao, Xuan P.A."},{"first_name":"Ion","full_name":"Errea, Ion","last_name":"Errea"},{"last_name":"Nikitin","full_name":"Nikitin, Alexey Y.","first_name":"Alexey Y."},{"last_name":"Hillenbrand","first_name":"Rainer","full_name":"Hillenbrand, Rainer"},{"full_name":"Martín-Sánchez, Javier","first_name":"Javier","last_name":"Martín-Sánchez"},{"last_name":"Alonso-González","full_name":"Alonso-González, Pablo","first_name":"Pablo"}],"date_updated":"2025-04-23T14:24:58Z","OA_place":"repository","_id":"7792","scopus_import":"1","year":"2020","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2501.08705"}],"abstract":[{"lang":"eng","text":"Phonon polaritons—light coupled to lattice vibrations—in polar van der Waals crystals are promising candidates for controlling the flow of energy on the nanoscale due to their strong field confinement, anisotropic propagation and ultra-long lifetime in the picosecond range1,2,3,4,5. However, the lack of tunability of their narrow and material-specific spectral range—the Reststrahlen band—severely limits their technological implementation. Here, we demonstrate that intercalation of Na atoms in the van der Waals semiconductor α-V2O5 enables a broad spectral shift of Reststrahlen bands, and that the phonon polaritons excited show ultra-low losses (lifetime of 4 ± 1 ps), similar to phonon polaritons in a non-intercalated crystal (lifetime of 6 ± 1 ps). We expect our intercalation method to be applicable to other van der Waals crystals, opening the door for the use of phonon polaritons in broad spectral bands in the mid-infrared domain."}],"publication":"Nature Materials","month":"09","department":[{"_id":"NanoFab"}],"pmid":1,"language":[{"iso":"eng"}],"publication_status":"published","arxiv":1,"citation":{"ieee":"J. Taboada-Gutiérrez <i>et al.</i>, “Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation,” <i>Nature Materials</i>, vol. 19. Springer Nature, pp. 964–968, 2020.","ama":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, et al. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. 2020;19:964–968. doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>","short":"J. Taboada-Gutiérrez, G. Álvarez-Pérez, J. Duan, W. Ma, K. Crowley, I. Prieto Gonzalez, A. Bylinkin, M. Autore, H. Volkova, K. Kimura, T. Kimura, M.H. Berger, S. Li, Q. Bao, X.P.A. Gao, I. Errea, A.Y. Nikitin, R. Hillenbrand, J. Martín-Sánchez, P. Alonso-González, Nature Materials 19 (2020) 964–968.","chicago":"Taboada-Gutiérrez, Javier, Gonzalo Álvarez-Pérez, Jiahua Duan, Weiliang Ma, Kyle Crowley, Ivan Prieto Gonzalez, Andrei Bylinkin, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>.","mla":"Taboada-Gutiérrez, Javier, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>, vol. 19, Springer Nature, 2020, pp. 964–968, doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>.","apa":"Taboada-Gutiérrez, J., Álvarez-Pérez, G., Duan, J., Ma, W., Crowley, K., Prieto Gonzalez, I., … Alonso-González, P. (2020). Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>","ista":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, Ma W, Crowley K, Prieto Gonzalez I, Bylinkin A, Autore M, Volkova H, Kimura K, Kimura T, Berger MH, Li S, Bao Q, Gao XPA, Errea I, Nikitin AY, Hillenbrand R, Martín-Sánchez J, Alonso-González P. 2020. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. Nature Materials. 19, 964–968."},"isi":1,"oa":1,"external_id":{"arxiv":["2501.08705"],"pmid":["32284598"],"isi":["000526218500004"]},"page":"964–968","OA_type":"green","intvolume":"        19","date_created":"2020-05-03T22:00:49Z","acknowledgement":"J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa Program from the Government of the Principality of Asturias (nos. PA-18-PF-BP17-126 and PA-20-PF-BP19-053, respectively). J.M.-S. acknowledges finantial support from the Clarín Programme from the Government of the Principality of Asturias and a Marie Curie-COFUND grant (PA-18-ACB17-29) and the Ramón y Cajal Program from the Government of Spain (RYC2018-026196-I). K.C., X.P.A.G., H.V. and M.H.B. acknowledge the Air Force Office of Scientific Research (AFOSR) grant no. FA 9550-18-1-0030 for funding support. I.E. acknowledges financial support from the Spanish Ministry of Economy and Competitiveness (grant no. FIS2016-76617-P). A.Y.N. acknowledges the Spanish Ministry of Science, Innovation and Universities (national project no. MAT2017-88358-C3-3-R) and the Basque Government (grant no. IT1164-19). Q.B. acknowledges the support from Australian Research Council (grant nos. FT150100450, IH150100006 and CE170100039). R.H. acknowledges support from the Spanish Ministry of Economy, Industry, and Competitiveness (national project RTI2018-094830-B-100 and the Project MDM-2016-0618 of the María de Maeztu Units of Excellence Program) and the Basque Goverment (grant no. IT1164-19). P.A.-G. acknowledges support from the European Research Council under starting grant no. 715496, 2DNANOPTICA.","type":"journal_article","article_processing_charge":"No","volume":19,"publisher":"Springer Nature"},{"ddc":["580"],"intvolume":"         9","date_created":"2020-05-04T08:50:47Z","has_accepted_license":"1","volume":9,"publisher":"eLife Sciences Publications","article_processing_charge":"No","type":"journal_article","publication_status":"published","language":[{"iso":"eng"}],"pmid":1,"citation":{"ieee":"A. Kuhn <i>et al.</i>, “Direct ETTIN-auxin interaction controls chromatin states in gynoecium development,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020.","short":"A. Kuhn, S. Ramans Harborough, H.M. McLaughlin, B. Natarajan, I. Verstraeten, J. Friml, S. Kepinski, L. Østergaard, ELife 9 (2020).","ama":"Kuhn A, Ramans Harborough S, McLaughlin HM, et al. Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/elife.51787\">10.7554/elife.51787</a>","ista":"Kuhn A, Ramans Harborough S, McLaughlin HM, Natarajan B, Verstraeten I, Friml J, Kepinski S, Østergaard L. 2020. Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. eLife. 9, e51787.","mla":"Kuhn, André, et al. “Direct ETTIN-Auxin Interaction Controls Chromatin States in Gynoecium Development.” <i>ELife</i>, vol. 9, e51787, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/elife.51787\">10.7554/elife.51787</a>.","apa":"Kuhn, A., Ramans Harborough, S., McLaughlin, H. M., Natarajan, B., Verstraeten, I., Friml, J., … Østergaard, L. (2020). Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.51787\">https://doi.org/10.7554/elife.51787</a>","chicago":"Kuhn, André, Sigurd Ramans Harborough, Heather M McLaughlin, Bhavani Natarajan, Inge Verstraeten, Jiří Friml, Stefan Kepinski, and Lars Østergaard. “Direct ETTIN-Auxin Interaction Controls Chromatin States in Gynoecium Development.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/elife.51787\">https://doi.org/10.7554/elife.51787</a>."},"isi":1,"oa":1,"external_id":{"pmid":["32267233"],"isi":["000527752200001"]},"article_number":"e51787","author":[{"first_name":"André","full_name":"Kuhn, André","last_name":"Kuhn"},{"last_name":"Ramans Harborough","first_name":"Sigurd","full_name":"Ramans Harborough, Sigurd"},{"full_name":"McLaughlin, Heather M","first_name":"Heather M","last_name":"McLaughlin"},{"full_name":"Natarajan, Bhavani","first_name":"Bhavani","last_name":"Natarajan"},{"orcid":"0000-0001-7241-2328","full_name":"Verstraeten, Inge","first_name":"Inge","last_name":"Verstraeten","id":"362BF7FE-F248-11E8-B48F-1D18A9856A87"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jiří","first_name":"Jiří"},{"first_name":"Stefan","full_name":"Kepinski, Stefan","last_name":"Kepinski"},{"last_name":"Østergaard","full_name":"Østergaard, Lars","first_name":"Lars"}],"article_type":"original","file":[{"file_name":"2020_eLife_Kuhn.pdf","date_updated":"2020-07-14T12:48:03Z","access_level":"open_access","checksum":"15d740de1a741fdcc6ec128c48eed017","relation":"main_file","date_created":"2020-05-04T09:06:43Z","content_type":"application/pdf","file_id":"7794","creator":"dernst","file_size":2893082}],"quality_controlled":"1","date_updated":"2023-08-21T06:17:12Z","_id":"7793","year":"2020","file_date_updated":"2020-07-14T12:48:03Z","scopus_import":"1","publication":"eLife","month":"04","abstract":[{"text":"Hormonal signalling in animals often involves direct transcription factor-hormone interactions that modulate gene expression. In contrast, plant hormone signalling is most commonly based on de-repression via the degradation of transcriptional repressors. Recently, we uncovered a non-canonical signalling mechanism for the plant hormone auxin whereby auxin directly affects the activity of the atypical auxin response factor (ARF), ETTIN towards target genes without the requirement for protein degradation. Here we show that ETTIN directly binds auxin, leading to dissociation from co-repressor proteins of the TOPLESS/TOPLESS-RELATED family followed by histone acetylation and induction of gene expression. This mechanism is reminiscent of animal hormone signalling as it affects the activity towards regulation of target genes and provides the first example of a DNA-bound hormone receptor in plants. Whilst auxin affects canonical ARFs indirectly by facilitating degradation of Aux/IAA repressors, direct ETTIN-auxin interactions allow switching between repressive and de-repressive chromatin states in an instantly-reversible manner.","lang":"eng"}],"department":[{"_id":"JiFr"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"publication_identifier":{"issn":["2050-084X"]},"title":"Direct ETTIN-auxin interaction controls chromatin states in gynoecium development","date_published":"2020-04-08T00:00:00Z","doi":"10.7554/elife.51787","oa_version":"Published Version","day":"08","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public"},{"author":[{"first_name":"Artur","full_name":"Czumaj, Artur","last_name":"Czumaj","orcid":"0000-0002-5646-9524"},{"full_name":"Davies, Peter","first_name":"Peter","last_name":"Davies","orcid":"0000-0002-5646-9524","id":"11396234-BB50-11E9-B24C-90FCE5697425"},{"first_name":"Merav","full_name":"Parter, Merav","last_name":"Parter"}],"quality_controlled":"1","date_updated":"2025-04-15T06:54:47Z","_id":"7802","year":"2020","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1912.05390"}],"scopus_import":"1","publication":"Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)","month":"07","abstract":[{"text":"The Massively Parallel Computation (MPC) model is an emerging model which distills core  aspects of distributed and parallel computation. It has been developed as a tool to solve (typically graph) problems in systems where the input is distributed over many machines with limited space.\r\n\t\r\nRecent work has focused on the regime in which machines have sublinear (in $n$, the number of nodes in the input graph) space, with randomized algorithms presented for fundamental graph problems of Maximal Matching and Maximal Independent Set. However, there have been no prior corresponding deterministic algorithms.\r\n\t\r\n\tA major challenge underlying the sublinear space setting is that the local space of each machine might be too small to store all the edges incident to a single node. This poses a considerable obstacle compared to the classical models in which each node is assumed to know and have easy access to its incident edges. To overcome this barrier we introduce a new graph sparsification technique that deterministically computes a low-degree subgraph with additional desired properties. The degree of the nodes in this subgraph is small in the sense that the edges of each node can be now stored on a single machine. This low-degree subgraph also has the property that solving the problem on this subgraph provides \\emph{significant} global progress, i.e., progress towards solving the problem for the original input graph.\r\n\t\r\nUsing this framework to derandomize the well-known randomized algorithm of Luby [SICOMP'86], we obtain $O(\\log \\Delta+\\log\\log n)$-round deterministic MPC algorithms for solving the fundamental problems of Maximal Matching and Maximal Independent Set with $O(n^{\\epsilon})$ space on each machine for any constant $\\epsilon > 0$. Based on the recent work of Ghaffari et al. [FOCS'18], this additive $O(\\log\\log n)$ factor is conditionally essential. These algorithms can also be shown to run in $O(\\log \\Delta)$ rounds in the closely related model of CONGESTED CLIQUE, improving upon the state-of-the-art bound of $O(\\log^2 \\Delta)$ rounds by Censor-Hillel et al. [DISC'17].","lang":"eng"}],"department":[{"_id":"DaAl"}],"related_material":{"record":[{"status":"public","id":"9541","relation":"later_version"}]},"title":"Graph sparsification for derandomizing massively parallel computation with low space","date_published":"2020-07-01T00:00:00Z","doi":"10.1145/3350755.3400282","oa_version":"Preprint","issue":"7","day":"01","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","status":"public","project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411"}],"date_created":"2020-05-06T08:53:34Z","type":"conference","publisher":"Association for Computing Machinery","article_processing_charge":"No","ec_funded":1,"language":[{"iso":"eng"}],"publication_status":"published","arxiv":1,"citation":{"ieee":"A. Czumaj, P. Davies, and M. Parter, “Graph sparsification for derandomizing massively parallel computation with low space,” in <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, Virtual Event, United States, 2020, no. 7, pp. 175–185.","ama":"Czumaj A, Davies P, Parter M. Graph sparsification for derandomizing massively parallel computation with low space. In: <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>. Association for Computing Machinery; 2020:175-185. doi:<a href=\"https://doi.org/10.1145/3350755.3400282\">10.1145/3350755.3400282</a>","short":"A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020), Association for Computing Machinery, 2020, pp. 175–185.","mla":"Czumaj, Artur, et al. “Graph Sparsification for Derandomizing Massively Parallel Computation with Low Space.” <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, no. 7, Association for Computing Machinery, 2020, pp. 175–85, doi:<a href=\"https://doi.org/10.1145/3350755.3400282\">10.1145/3350755.3400282</a>.","apa":"Czumaj, A., Davies, P., &#38; Parter, M. (2020). Graph sparsification for derandomizing massively parallel computation with low space. In <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i> (pp. 175–185). Virtual Event, United States: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3350755.3400282\">https://doi.org/10.1145/3350755.3400282</a>","chicago":"Czumaj, Artur, Peter Davies, and Merav Parter. “Graph Sparsification for Derandomizing Massively Parallel Computation with Low Space.” In <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, 175–85. Association for Computing Machinery, 2020. <a href=\"https://doi.org/10.1145/3350755.3400282\">https://doi.org/10.1145/3350755.3400282</a>.","ista":"Czumaj A, Davies P, Parter M. 2020. Graph sparsification for derandomizing massively parallel computation with low space. Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020). SPAA: Symposium on Parallelism in Algorithms and Architectures, 175–185."},"isi":1,"conference":{"end_date":"2020-07-17","location":"Virtual Event, United States","start_date":"2020-07-15","name":"SPAA: Symposium on Parallelism in Algorithms and Architectures"},"external_id":{"isi":["000744436200015"],"arxiv":["1912.05390"]},"oa":1,"page":"175-185"},{"month":"07","publication":"Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing","abstract":[{"text":"We settle the complexity of the (Δ+1)-coloring and (Δ+1)-list coloring problems in the CONGESTED CLIQUE model by presenting a simple deterministic algorithm for both problems running in a constant number of rounds. This matches the complexity of the recent breakthrough randomized constant-round (Δ+1)-list coloring algorithm due to Chang et al. (PODC'19), and significantly improves upon the state-of-the-art O(logΔ)-round deterministic (Δ+1)-coloring bound of Parter (ICALP'18).\r\nA remarkable property of our algorithm is its simplicity. Whereas the state-of-the-art randomized algorithms for this problem are based on the quite involved local coloring algorithm of Chang et al. (STOC'18), our algorithm can be described in just a few lines. At a high level, it applies a careful derandomization of a recursive procedure which partitions the nodes and their respective palettes into separate bins. We show that after O(1) recursion steps, the remaining uncolored subgraph within each bin has linear size, and thus can be solved locally by collecting it to a single node. This algorithm can also be implemented in the Massively Parallel Computation (MPC) model provided that each machine has linear (in n, the number of nodes in the input graph) space.\r\nWe also show an extension of our algorithm to the MPC regime in which machines have sublinear space: we present the first deterministic (Δ+1)-list coloring algorithm designed for sublinear-space MPC, which runs in O(logΔ+loglogn) rounds.","lang":"eng"}],"department":[{"_id":"DaAl"}],"_id":"7803","year":"2020","scopus_import":"1","file_date_updated":"2020-10-08T08:17:36Z","author":[{"first_name":"Artur","full_name":"Czumaj, Artur","last_name":"Czumaj","orcid":"0000-0002-5646-9524"},{"orcid":"0000-0002-5646-9524","last_name":"Davies","full_name":"Davies, Peter","first_name":"Peter","id":"11396234-BB50-11E9-B24C-90FCE5697425"},{"last_name":"Parter","full_name":"Parter, Merav","first_name":"Merav"}],"quality_controlled":"1","file":[{"relation":"main_file","date_created":"2020-10-08T08:17:36Z","checksum":"46fe4fc58a64eb04068115573f631d4c","success":1,"file_size":520051,"file_id":"8624","content_type":"application/pdf","creator":"pdavies","file_name":"ColoringArxiv.pdf","date_updated":"2020-10-08T08:17:36Z","access_level":"open_access"}],"date_updated":"2025-09-10T10:18:18Z","day":"01","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","date_published":"2020-07-01T00:00:00Z","doi":"10.1145/3382734.3405751","oa_version":"Submitted Version","title":"Simple, deterministic, constant-round coloring in the congested clique","type":"conference","article_processing_charge":"No","ec_funded":1,"publisher":"Association for Computing Machinery","date_created":"2020-05-06T09:02:14Z","has_accepted_license":"1","ddc":["000"],"project":[{"name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"page":"309-318","isi":1,"conference":{"location":"Salerno, Italy","end_date":"2020-08-07","start_date":"2020-08-03","name":"PODC: Symposium on Principles of Distributed Computing"},"external_id":{"isi":["001436693500042"],"arxiv":["2009.06043"]},"oa":1,"arxiv":1,"citation":{"ama":"Czumaj A, Davies P, Parter M. Simple, deterministic, constant-round coloring in the congested clique. In: <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2020:309-318. doi:<a href=\"https://doi.org/10.1145/3382734.3405751\">10.1145/3382734.3405751</a>","short":"A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2020, pp. 309–318.","ieee":"A. Czumaj, P. Davies, and M. Parter, “Simple, deterministic, constant-round coloring in the congested clique,” in <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, Salerno, Italy, 2020, pp. 309–318.","chicago":"Czumaj, Artur, Peter Davies, and Merav Parter. “Simple, Deterministic, Constant-Round Coloring in the Congested Clique.” In <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, 309–18. Association for Computing Machinery, 2020. <a href=\"https://doi.org/10.1145/3382734.3405751\">https://doi.org/10.1145/3382734.3405751</a>.","mla":"Czumaj, Artur, et al. “Simple, Deterministic, Constant-Round Coloring in the Congested Clique.” <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2020, pp. 309–18, doi:<a href=\"https://doi.org/10.1145/3382734.3405751\">10.1145/3382734.3405751</a>.","apa":"Czumaj, A., Davies, P., &#38; Parter, M. (2020). Simple, deterministic, constant-round coloring in the congested clique. In <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i> (pp. 309–318). Salerno, Italy: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3382734.3405751\">https://doi.org/10.1145/3382734.3405751</a>","ista":"Czumaj A, Davies P, Parter M. 2020. Simple, deterministic, constant-round coloring in the congested clique. Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 309–318."},"language":[{"iso":"eng"}],"publication_status":"published"},{"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","doi":"10.1137/1.9781611975994.172","date_published":"2020-01-01T00:00:00Z","oa_version":"Submitted Version","publication_identifier":{"isbn":["9781611975994"]},"title":"Connectivity of triangulation flip graphs in the plane (Part I: Edge flips)","abstract":[{"text":"In a straight-line embedded triangulation of a point set P in the plane, removing an inner edge and—provided the resulting quadrilateral is convex—adding the other diagonal is called an edge flip. The (edge) flip graph has all triangulations as vertices, and a pair of triangulations is adjacent if they can be obtained from each other by an edge flip. The goal of this paper is to contribute to a better understanding of the flip graph, with an emphasis on its connectivity.\r\nFor sets in general position, it is known that every triangulation allows at least edge flips (a tight bound) which gives the minimum degree of any flip graph for n points. We show that for every point set P in general position, the flip graph is at least -vertex connected. Somewhat more strongly, we show that the vertex connectivity equals the minimum degree occurring in the flip graph, i.e. the minimum number of flippable edges in any triangulation of P, provided P is large enough. Finally, we exhibit some of the geometry of the flip graph by showing that the flip graph can be covered by 1-skeletons of polytopes of dimension (products of associahedra).\r\nA corresponding result ((n – 3)-vertex connectedness) can be shown for the bistellar flip graph of partial triangulations, i.e. the set of all triangulations of subsets of P which contain all extreme points of P. This will be treated separately in a second part.","lang":"eng"}],"month":"01","publication":"Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms","related_material":{"record":[{"relation":"later_version","status":"public","id":"12129"}]},"department":[{"_id":"UlWa"}],"_id":"7807","scopus_import":1,"year":"2020","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1137/1.9781611975994.172"}],"quality_controlled":"1","author":[{"id":"36690CA2-F248-11E8-B48F-1D18A9856A87","last_name":"Wagner","first_name":"Uli","full_name":"Wagner, Uli","orcid":"0000-0002-1494-0568"},{"first_name":"Emo","full_name":"Welzl, Emo","last_name":"Welzl"}],"date_updated":"2024-10-09T21:03:33Z","page":"2823-2841","conference":{"end_date":"2020-01-08","location":"Salt Lake City, UT, United States","start_date":"2020-01-05","name":"SODA: Symposium on Discrete Algorithms"},"oa":1,"external_id":{"arxiv":["2003.13557"]},"arxiv":1,"citation":{"ama":"Wagner U, Welzl E. Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). In: <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Vol 2020-January. SIAM; 2020:2823-2841. doi:<a href=\"https://doi.org/10.1137/1.9781611975994.172\">10.1137/1.9781611975994.172</a>","short":"U. Wagner, E. Welzl, in:, Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2020, pp. 2823–2841.","ieee":"U. Wagner and E. Welzl, “Connectivity of triangulation flip graphs in the plane (Part I: Edge flips),” in <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Salt Lake City, UT, United States, 2020, vol. 2020–January, pp. 2823–2841.","mla":"Wagner, Uli, and Emo Welzl. “Connectivity of Triangulation Flip Graphs in the Plane (Part I: Edge Flips).” <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, vol. 2020–January, SIAM, 2020, pp. 2823–41, doi:<a href=\"https://doi.org/10.1137/1.9781611975994.172\">10.1137/1.9781611975994.172</a>.","chicago":"Wagner, Uli, and Emo Welzl. “Connectivity of Triangulation Flip Graphs in the Plane (Part I: Edge Flips).” In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 2020–January:2823–41. SIAM, 2020. <a href=\"https://doi.org/10.1137/1.9781611975994.172\">https://doi.org/10.1137/1.9781611975994.172</a>.","apa":"Wagner, U., &#38; Welzl, E. (2020). Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i> (Vol. 2020–January, pp. 2823–2841). Salt Lake City, UT, United States: SIAM. <a href=\"https://doi.org/10.1137/1.9781611975994.172\">https://doi.org/10.1137/1.9781611975994.172</a>","ista":"Wagner U, Welzl E. 2020. Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms vol. 2020–January, 2823–2841."},"publication_status":"published","language":[{"iso":"eng"}],"type":"conference","publisher":"SIAM","article_processing_charge":"No","volume":"2020-January","date_created":"2020-05-10T22:00:48Z"},{"file":[{"checksum":"a24ec24e38d843341ae620ec76c53688","relation":"main_file","date_created":"2020-05-11T11:34:08Z","creator":"dernst","content_type":"application/pdf","file_id":"7818","file_size":1402146,"file_name":"2020_FrontiersEduc_Beattie.pdf","date_updated":"2020-07-14T12:48:03Z","access_level":"open_access"}],"quality_controlled":"1","article_type":"original","author":[{"orcid":"0000-0002-8483-8753","first_name":"Robert J","full_name":"Beattie, Robert J","last_name":"Beattie","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87"},{"id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon","first_name":"Simon","orcid":"0000-0003-2279-1061"},{"first_name":"Florian","full_name":"Pauler, Florian","last_name":"Pauler","orcid":"0000-0002-7462-0048","id":"48EA0138-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2024-10-22T10:46:38Z","corr_author":"1","abstract":[{"text":"Scientific research is to date largely restricted to wealthy laboratories in developed nations due to the necessity of complex and expensive equipment. This inequality limits the capacity of science to be used as a diplomatic channel. Maker movements use open-source technologies including additive manufacturing (3D printing) and laser cutting, together with low-cost computers for developing novel products. This movement is setting the groundwork for a revolution, allowing scientific equipment to be sourced at a fraction of the cost and has the potential to increase the availability of equipment for scientists around the world. Science education is increasingly recognized as another channel for science diplomacy. In this perspective, we introduce the idea that the Maker movement and open-source technologies have the potential to revolutionize science, technology, engineering and mathematics (STEM) education worldwide. We present an open-source STEM didactic tool called SCOPES (Sparking Curiosity through Open-source Platforms in Education and Science). SCOPES is self-contained, independent of local resources, and cost-effective. SCOPES can be adapted to communicate complex subjects from genetics to neurobiology, perform real-world biological experiments and explore digitized scientific samples. We envision such platforms will enhance science diplomacy by providing a means for scientists to share their findings with classrooms and for educators to incorporate didactic concepts into STEM lessons. By providing students the opportunity to design, perform, and share scientific experiments, students also experience firsthand the benefits of a multinational scientific community. We provide instructions on how to build and use SCOPES on our webpage: http://scopeseducation.org.","lang":"eng"}],"month":"05","publication":"Frontiers in Education","department":[{"_id":"SiHi"}],"_id":"7814","scopus_import":"1","file_date_updated":"2020-07-14T12:48:03Z","year":"2020","publication_identifier":{"issn":["2504-284X"]},"title":"SCOPES: Sparking curiosity through Open-Source platforms in education and science","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"},{"_id":"EM-Fac"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"08","doi":"10.3389/feduc.2020.00048","date_published":"2020-05-08T00:00:00Z","oa_version":"Published Version","intvolume":"         5","ddc":["570"],"project":[{"grant_number":"M02416","call_identifier":"FWF","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex","_id":"264E56E2-B435-11E9-9278-68D0E5697425"},{"_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","call_identifier":"H2020","grant_number":"725780"}],"ec_funded":1,"type":"journal_article","publisher":"Frontiers Media","article_processing_charge":"No","volume":5,"date_created":"2020-05-11T08:18:48Z","has_accepted_license":"1","citation":{"mla":"Beattie, Robert J., et al. “SCOPES: Sparking Curiosity through Open-Source Platforms in Education and Science.” <i>Frontiers in Education</i>, vol. 5, 48, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/feduc.2020.00048\">10.3389/feduc.2020.00048</a>.","apa":"Beattie, R. J., Hippenmeyer, S., &#38; Pauler, F. (2020). SCOPES: Sparking curiosity through Open-Source platforms in education and science. <i>Frontiers in Education</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/feduc.2020.00048\">https://doi.org/10.3389/feduc.2020.00048</a>","chicago":"Beattie, Robert J, Simon Hippenmeyer, and Florian Pauler. “SCOPES: Sparking Curiosity through Open-Source Platforms in Education and Science.” <i>Frontiers in Education</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/feduc.2020.00048\">https://doi.org/10.3389/feduc.2020.00048</a>.","ista":"Beattie RJ, Hippenmeyer S, Pauler F. 2020. SCOPES: Sparking curiosity through Open-Source platforms in education and science. Frontiers in Education. 5, 48.","ieee":"R. J. Beattie, S. Hippenmeyer, and F. Pauler, “SCOPES: Sparking curiosity through Open-Source platforms in education and science,” <i>Frontiers in Education</i>, vol. 5. Frontiers Media, 2020.","ama":"Beattie RJ, Hippenmeyer S, Pauler F. SCOPES: Sparking curiosity through Open-Source platforms in education and science. <i>Frontiers in Education</i>. 2020;5. doi:<a href=\"https://doi.org/10.3389/feduc.2020.00048\">10.3389/feduc.2020.00048</a>","short":"R.J. Beattie, S. Hippenmeyer, F. Pauler, Frontiers in Education 5 (2020)."},"publication_status":"published","language":[{"iso":"eng"}],"article_number":"48","oa":1},{"citation":{"apa":"Bouchal, R., Li, Z., Bongu, C., Le Vot, S., Berthelot, R., Rotenberg, B., … Fontaine, O. (2020). Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202005378\">https://doi.org/10.1002/anie.202005378</a>","chicago":"Bouchal, Roza, Zhujie Li, Chandra Bongu, Steven Le Vot, Romain Berthelot, Benjamin Rotenberg, Fréderic Favier, Stefan Alexander Freunberger, Mathieu Salanne, and Olivier Fontaine. “Competitive Salt Precipitation/Dissolution during Free‐water Reduction in Water‐in‐salt Electrolyte.” <i>Angewandte Chemie International Edition</i>. Wiley, 2020. <a href=\"https://doi.org/10.1002/anie.202005378\">https://doi.org/10.1002/anie.202005378</a>.","mla":"Bouchal, Roza, et al. “Competitive Salt Precipitation/Dissolution during Free‐water Reduction in Water‐in‐salt Electrolyte.” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 37, Wiley, 2020, pp. 15913–1591, doi:<a href=\"https://doi.org/10.1002/anie.202005378\">10.1002/anie.202005378</a>.","ista":"Bouchal R, Li Z, Bongu C, Le Vot S, Berthelot R, Rotenberg B, Favier F, Freunberger SA, Salanne M, Fontaine O. 2020. Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. Angewandte Chemie International Edition. 59(37), 15913–1591.","ama":"Bouchal R, Li Z, Bongu C, et al. Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. <i>Angewandte Chemie International Edition</i>. 2020;59(37):15913-1591. doi:<a href=\"https://doi.org/10.1002/anie.202005378\">10.1002/anie.202005378</a>","short":"R. Bouchal, Z. Li, C. Bongu, S. Le Vot, R. Berthelot, B. Rotenberg, F. Favier, S.A. Freunberger, M. Salanne, O. Fontaine, Angewandte Chemie International Edition 59 (2020) 15913–1591.","ieee":"R. Bouchal <i>et al.</i>, “Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte,” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 37. Wiley, pp. 15913–1591, 2020."},"language":[{"iso":"eng"}],"pmid":1,"publication_status":"published","page":"15913-1591","oa":1,"external_id":{"pmid":["32390281"],"isi":["000541488700001"]},"isi":1,"intvolume":"        59","ddc":["540","546"],"publisher":"Wiley","type":"journal_article","article_processing_charge":"No","volume":59,"date_created":"2020-05-14T21:00:30Z","has_accepted_license":"1","title":"Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","day":"07","issue":"37","oa_version":"Published Version","doi":"10.1002/anie.202005378","date_published":"2020-09-07T00:00:00Z","date_updated":"2023-09-05T16:02:53Z","quality_controlled":"1","article_type":"original","file":[{"file_id":"8400","creator":"dernst","content_type":"application/pdf","file_size":1966184,"success":1,"checksum":"7b6c2fc20e9b0ff4353352f7a7004e2d","relation":"main_file","date_created":"2020-09-17T08:57:16Z","access_level":"open_access","date_updated":"2020-09-17T08:57:16Z","file_name":"2020_AngChemieINT_Buchal.pdf"}],"author":[{"last_name":"Bouchal","full_name":"Bouchal, Roza","first_name":"Roza"},{"last_name":"Li","full_name":"Li, Zhujie","first_name":"Zhujie"},{"full_name":"Bongu, Chandra","first_name":"Chandra","last_name":"Bongu"},{"last_name":"Le Vot","full_name":"Le Vot, Steven","first_name":"Steven"},{"last_name":"Berthelot","first_name":"Romain","full_name":"Berthelot, Romain"},{"last_name":"Rotenberg","full_name":"Rotenberg, Benjamin","first_name":"Benjamin"},{"full_name":"Favier, Fréderic","first_name":"Fréderic","last_name":"Favier"},{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","last_name":"Freunberger","first_name":"Stefan Alexander","full_name":"Freunberger, Stefan Alexander"},{"first_name":"Mathieu","full_name":"Salanne, Mathieu","last_name":"Salanne"},{"first_name":"Olivier","full_name":"Fontaine, Olivier","last_name":"Fontaine"}],"department":[{"_id":"StFr"}],"abstract":[{"text":"Water-in-salt electrolytes based on highly concentrated bis(trifluoromethyl)sulfonimide (TFSI) promise aqueous electrolytes with stabilities nearing 3 V. However, especially with an electrode approaching the cathodic (reductive) stability, cycling stability is insufficient. While stability critically relies on a solid electrolyte interphase (SEI), the mechanism behind the cathodic stability limit remains unclear. Here, we reveal two distinct reduction potentials for the chemical environments of 'free' and 'bound' water and that both contribute to SEI formation. Free-water is reduced ~1V above bound water in a hydrogen evolution reaction (HER) and responsible for SEI formation via reactive intermediates of the HER; concurrent LiTFSI precipitation/dissolution establishes a dynamic interface. The free-water population emerges, therefore, as the handle to extend the cathodic limit of aqueous electrolytes and the battery cycling stability. ","lang":"eng"}],"publication":"Angewandte Chemie International Edition","month":"09","scopus_import":"1","file_date_updated":"2020-09-17T08:57:16Z","year":"2020","_id":"7847"}]
