[{"citation":{"ista":"Yu A, Chang X, Lu X, He R, Yang L, Chai J, Bi X, Chacón-Borrero J, Mejia-Centeno KV, Llorca J, Villalobos-Portillo E, Liu Q, Shang J, Cabot A. 2026. Lattice-level defect engineering of dense Mn2O3 hosts unlocks fast H+/Zn2+ storage and long-life aqueous zinc-ion batteries. Journal of Materials Chemistry A.","short":"A. Yu, X. Chang, X. Lu, R. He, L. Yang, J. Chai, X. Bi, J. Chacón-Borrero, K.V. Mejia-Centeno, J. Llorca, E. Villalobos-Portillo, Q. Liu, J. Shang, A. Cabot, Journal of Materials Chemistry A (2026).","chicago":"Yu, Ao, Xingqi Chang, Xuan Lu, Ren He, Linlin Yang, Jiali Chai, Xiaoyu Bi, et al. “Lattice-Level Defect Engineering of Dense Mn2O3 Hosts Unlocks Fast H+/Zn2+ Storage and Long-Life Aqueous Zinc-Ion Batteries.” <i>Journal of Materials Chemistry A</i>. Royal Society of Chemistry, 2026. <a href=\"https://doi.org/10.1039/d6ta05844b\">https://doi.org/10.1039/d6ta05844b</a>.","ieee":"A. Yu <i>et al.</i>, “Lattice-level defect engineering of dense Mn2O3 hosts unlocks fast H+/Zn2+ storage and long-life aqueous zinc-ion batteries,” <i>Journal of Materials Chemistry A</i>. Royal Society of Chemistry, 2026.","mla":"Yu, Ao, et al. “Lattice-Level Defect Engineering of Dense Mn2O3 Hosts Unlocks Fast H+/Zn2+ Storage and Long-Life Aqueous Zinc-Ion Batteries.” <i>Journal of Materials Chemistry A</i>, Royal Society of Chemistry, 2026, doi:<a href=\"https://doi.org/10.1039/d6ta05844b\">10.1039/d6ta05844b</a>.","ama":"Yu A, Chang X, Lu X, et al. Lattice-level defect engineering of dense Mn2O3 hosts unlocks fast H+/Zn2+ storage and long-life aqueous zinc-ion batteries. <i>Journal of Materials Chemistry A</i>. 2026. doi:<a href=\"https://doi.org/10.1039/d6ta05844b\">10.1039/d6ta05844b</a>","apa":"Yu, A., Chang, X., Lu, X., He, R., Yang, L., Chai, J., … Cabot, A. (2026). Lattice-level defect engineering of dense Mn2O3 hosts unlocks fast H+/Zn2+ storage and long-life aqueous zinc-ion batteries. <i>Journal of Materials Chemistry A</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d6ta05844b\">https://doi.org/10.1039/d6ta05844b</a>"},"year":"2026","OA_type":"closed access","quality_controlled":"1","status":"public","das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"Royal Society of Chemistry","title":"Lattice-level defect engineering of dense Mn2O3 hosts unlocks fast H+/Zn2+ storage and long-life aqueous zinc-ion batteries","date_published":"2026-08-31T00:00:00Z","doi":"10.1039/d6ta05844b","date_created":"2026-09-20T22:01:48Z","oa_version":"None","date_updated":"2026-10-06T10:34:27Z","article_type":"original","fulldoi":"https://doi.org/10.1039/d6ta05844b","scopus_import":"1","publication":"Journal of Materials Chemistry A","article_processing_charge":"No","researchdata_availability":"no","day":"31","month":"08","dataavailabilitystatement":"The data that support the findings of this study are available within the manuscript and the corresponding supplementary information (SI). Data are available upon request from the authors. Supplementary information is available. See DOI: https://doi.org/10.1039/d6ta05844b.","department":[{"_id":"MaIb"}],"publication_status":"epub_ahead","type":"journal_article","abstract":[{"lang":"eng","text":"Manganese-based aqueous zinc-ion batteries (AZIBs) have emerged as promising candidates for large-scale energy storage owing to their low cost, intrinsic safety, and the abundance of constituent elements. However, their practical deployment is still restricted by severe capacity fading caused by Jahn–Teller-induced structural instability and sluggish Zn2+ transport in the cathode. Although surface coating, heteroatom doping, and structural regulation have been widely explored to improve Mn-based cathodes, these approaches may suffer from increased interfacial resistance, compositional complexity, or limited control over the intrinsic electronic structure. In this context, oxygen-vacancy engineering offers a more direct route to modulate local coordination environments and accelerate Zn2+/H+ storage kinetics. Herein, lattice-level defect engineering of a dense Mn2O3 host is achieved through a metal–organic framework-derived synthesis followed by mild secondary annealing. The introduced oxygen vacancies regulate the local electronic structure and coordination environment, thereby facilitating Zn2+ diffusion, accelerating charge-transfer kinetics, and improving electrochemical reversibility. Combined experimental and theoretical investigations further show that oxygen-vacancy engineering enhances electronic conductivity, reduces the Zn2+ migration barrier, and enables a reversible dual-ion storage mechanism involving both H+ and Zn2+. Benefiting from these effects, the Zn‖Vo-Mn2O3 battery delivers a high specific capacity of 359 mAh g−1 at 0.3 A g−1, maintains 210 mAh g−1 at 6 A g−1, and retains 74.3% of its capacity after 10 000 cycles at 12 A g−1 after only 150 s of initial preconditioning. This work highlights oxygen-vacancy engineering as an effective route to enhancing the kinetic and structural stability of Mn-based cathodes for advanced AZIBs."}],"_id":"22965","acknowledgement":"Ao Y. acknowledges financial support from the China Scholarship Council (No. 202208320041), the National Natural Science Foundation of China (No. 22475231), and the Shenzhen Science and Technology Planning Project (No. KJZD20230923115227054). The XAS experiments were performed in collaboration with ALBA staff at the NOTOS beamline of ALBA Synchrotron (experiment ID: 2024028418), Barcelona, Spain. JL is a Serra Húnter Fellow and is grateful to the Academia Excellence program (Generalitat de Catalunya) and to the project PID2024-156765OB-C21 funded by MICIU/AEI/10.13039/501100011033 and the European Regional Development Fund (FEDER), and to the María de Maeztu Units of Excellence Programme CEX2023-001300 M, funded by MCIN/AEI/10.13039/501100011033.","author":[{"first_name":"Ao","last_name":"Yu","full_name":"Yu, Ao"},{"first_name":"Xingqi","last_name":"Chang","full_name":"Chang, Xingqi"},{"full_name":"Lu, Xuan","last_name":"Lu","first_name":"Xuan"},{"id":"366c4efa-f61c-11f0-808b-d12a4547ac69","full_name":"He, Ren","last_name":"He","first_name":"Ren"},{"full_name":"Yang, Linlin","last_name":"Yang","first_name":"Linlin"},{"full_name":"Chai, Jiali","last_name":"Chai","first_name":"Jiali"},{"full_name":"Bi, Xiaoyu","last_name":"Bi","first_name":"Xiaoyu"},{"full_name":"Chacón-Borrero, Jesús","first_name":"Jesús","last_name":"Chacón-Borrero"},{"first_name":"Karol V.","last_name":"Mejia-Centeno","full_name":"Mejia-Centeno, Karol V."},{"full_name":"Llorca, Jordi","first_name":"Jordi","last_name":"Llorca"},{"full_name":"Villalobos-Portillo, Eduardo","last_name":"Villalobos-Portillo","first_name":"Eduardo"},{"first_name":"Qirong","last_name":"Liu","full_name":"Liu, Qirong"},{"first_name":"Jian","last_name":"Shang","full_name":"Shang, Jian"},{"full_name":"Cabot, Andreu","first_name":"Andreu","last_name":"Cabot"}],"supplementarymaterial":"yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2050-7488"],"eissn":["2050-7496"]}},{"day":"22","month":"09","has_accepted_license":"1","researchdata_availability":"no","department":[{"_id":"MaIb"},{"_id":"GradSch"},{"_id":"NanoFab"}],"publication_status":"published","issue":"18","file_date_updated":"2026-10-06T12:11:04Z","file":[{"file_id":"23063","success":1,"relation":"main_file","file_name":"2026_ChemistryMaterials_Fiedler.pdf","date_updated":"2026-10-06T12:11:04Z","file_size":7461570,"access_level":"open_access","content_type":"application/pdf","date_created":"2026-10-06T12:11:04Z","creator":"dernst","checksum":"15e7866ca4fd57f5526737945651a6f2"}],"oa":1,"article_type":"original","fulldoi":"https://doi.org/10.1021/acs.chemmater.6c01284","scopus_import":"1","article_processing_charge":"Yes (via OA deal)","publication":"Chemistry of Materials","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"publication_identifier":{"issn":["0897-4756"],"eissn":["1520-5002"]},"page":"9323–9332","volume":38,"type":"journal_article","abstract":[{"lang":"eng","text":"Alkali salts are widely used in solution processing, yet the corresponding cations are often assumed to remain in the liquid phase. Here, we show that alkali ions introduced during the solution synthesis of SnSe are retained through particle isolation and continue to influence the material during subsequent thermal processing, where they shape the evolution of the final polycrystalline material. Different SnSe powders were prepared using Li+, Na+, and K+ precursors, as well as tetramethylammonium (TMA+) precursors as a nonalkali reference for comparison, and all samples were consolidated under identical conditions. Although all three alkali ions were found in the matrix, at grain boundaries, and in segregated nanoscale regions, they partitioned differently and resulted in distinct grain sizes, defect distributions, and therefore transport properties. Li induced the strongest grain size heterogeneity and the lowest energy barriers, Na the best overall balance between carrier concentration and mobility, and K the broadest alkali-rich grain boundary regions along with the strongest interfacial penalty to charge carrier transport. These results show that residual alkali ions are not just remnants of solution synthesis but active determinants of microstructure and thermoelectric performance in SnSe."}],"author":[{"last_name":"Fiedler","first_name":"Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","full_name":"Fiedler, Christine"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","full_name":"Horta, Sharona","last_name":"Horta","first_name":"Sharona"},{"full_name":"Navita, Navita","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","orcid":"0000-0001-7408-8197","first_name":"Navita","last_name":"Navita"},{"last_name":"Maji","first_name":"Krishnendu","id":"76bc9e9f-ba0b-11ee-8184-90edabd17a58","full_name":"Maji, Krishnendu"},{"orcid":"0000-0003-1537-7436","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","full_name":"Kleinhanns, Tobias","first_name":"Tobias","last_name":"Kleinhanns"},{"full_name":"Llorca, Jordi","last_name":"Llorca","first_name":"Jordi"},{"full_name":"Wang, Qi","id":"0d37923a-aca1-11ef-951f-fd411b71d5f0","first_name":"Qi","last_name":"Wang"},{"full_name":"Ramon, Maria Garcia","id":"1ffff7cd-ed76-11ed-8d5f-be5e7c364eb9","last_name":"Ramon","first_name":"Maria Garcia"},{"first_name":"Sambit","last_name":"Das","full_name":"Das, Sambit"},{"full_name":"Gavini, Vikram","first_name":"Vikram","last_name":"Gavini"},{"full_name":"Liu, Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7313-6740","last_name":"Liu","first_name":"Yu"},{"first_name":"Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843"}],"_id":"22967","acknowledgement":"ISTA and the Werner Siemens Foundation financially supported this work. The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF), Juan Aguilera Servin from the Nanofabrication facility (NNF). Special acknowledgments to the Ibá\r\nez group for their fruitful discussions and insights. K.M. acknowledges the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413 and PETRAIII at DESY for the synchrotron X-ray measurements under proposal No. I-20241048 EC. JL is a Serra Húnter Fellow and is grateful to the Academia Excellence program (Generalitat de Catalunya), project PID2024-156765OB-C21 funded by MICIU/AEI/10.13039/501100011033 and the European Regional Development Fund (FEDER), and María de Maeztu Units of Excellence Programme CEX2023-001300 M, funded by MCIN/AEI 10.13039/501100011033. VG and SD acknowledge the use of resources of the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Y.L. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411, the National Natural Science Foundation of China (NSFC) (Grants No. 22209034).","PlanS_conform":"1","supplementarymaterial":"yes","OA_type":"hybrid","OA_place":"publisher","year":"2026","ec_funded":1,"quality_controlled":"1","status":"public","citation":{"ista":"Fiedler C, Horta S, Jakhar N, Maji K, Kleinhanns T, Llorca J, Wang Q, Ramon MG, Das S, Gavini V, Liu Y, Ibáñez M. 2026. Alkali ions retained from synthesis govern microstructure and transport in solution-processed SnSe. Chemistry of Materials. 38(18), 9323–9332.","ama":"Fiedler C, Horta S, Jakhar N, et al. Alkali ions retained from synthesis govern microstructure and transport in solution-processed SnSe. <i>Chemistry of Materials</i>. 2026;38(18):9323–9332. doi:<a href=\"https://doi.org/10.1021/acs.chemmater.6c01284\">10.1021/acs.chemmater.6c01284</a>","apa":"Fiedler, C., Horta, S., Jakhar, N., Maji, K., Kleinhanns, T., Llorca, J., … Ibáñez, M. (2026). Alkali ions retained from synthesis govern microstructure and transport in solution-processed SnSe. <i>Chemistry of Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.chemmater.6c01284\">https://doi.org/10.1021/acs.chemmater.6c01284</a>","chicago":"Fiedler, Christine, Sharona Horta, Navita Jakhar, Krishnendu Maji, Tobias Kleinhanns, Jordi Llorca, Qi Wang, et al. “Alkali Ions Retained from Synthesis Govern Microstructure and Transport in Solution-Processed SnSe.” <i>Chemistry of Materials</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.chemmater.6c01284\">https://doi.org/10.1021/acs.chemmater.6c01284</a>.","short":"C. Fiedler, S. Horta, N. Jakhar, K. Maji, T. Kleinhanns, J. Llorca, Q. Wang, M.G. Ramon, S. Das, V. Gavini, Y. Liu, M. Ibáñez, Chemistry of Materials 38 (2026) 9323–9332.","ieee":"C. Fiedler <i>et al.</i>, “Alkali ions retained from synthesis govern microstructure and transport in solution-processed SnSe,” <i>Chemistry of Materials</i>, vol. 38, no. 18. American Chemical Society, pp. 9323–9332, 2026.","mla":"Fiedler, Christine, et al. “Alkali Ions Retained from Synthesis Govern Microstructure and Transport in Solution-Processed SnSe.” <i>Chemistry of Materials</i>, vol. 38, no. 18, American Chemical Society, 2026, pp. 9323–9332, doi:<a href=\"https://doi.org/10.1021/acs.chemmater.6c01284\">10.1021/acs.chemmater.6c01284</a>."},"intvolume":"        38","title":"Alkali ions retained from synthesis govern microstructure and transport in solution-processed SnSe","external_id":{"pmid":["42787739"]},"corr_author":"1","doi":"10.1021/acs.chemmater.6c01284","date_published":"2026-09-22T00:00:00Z","date_created":"2026-09-21T10:33:48Z","oa_version":"Published Version","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"},{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"},{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"pmid":1,"date_updated":"2026-10-06T12:16:03Z","ddc":["540"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"language":[{"iso":"eng"}],"publisher":"American Chemical Society","das_tickbox":"0"},{"abstract":[{"lang":"eng","text":"Genomic measurements of DNA methylation, gene expression or protein levels are becoming more prevalent and are increasingly used to study health outcomes. However, most proposed association testing methods consider only marginal effects of each feature on a single outcome variable and are not set up to handle highly correlated, continuous data. Here, we introduce MAJA, a method to learn shared and outcome-specific effects for multiple traits in multi-omics data. MAJA determines the unique contribution of individual loci, genes, or molecular pathways to variation in one or more traits, conditional on all other measured “omics” data genome-wide. Simulations show MAJA accurately finds shared and distinct associations between omics-data and multiple traits and estimates omics-specific (co)variances, allowing for sparsity and correlations within the data. Applying MAJA to 12 outcome traits in Generation Scotland methylation data (n = 18 264), we find novel shared epigenetic probes among cholesterol metabolism, osteoarthritis, blood pressure and asthma. In contrast to marginal testing, we find only 10 CpG probes with significant effects above the genome-wide background. This highlights the need for joint association testing in highly correlated methylation data from whole blood and for studies of increased sample size in order to refine epigenomic associations in observational data."}],"type":"journal_article","supplementarymaterial":"yes","author":[{"id":"30d4014e-7753-11eb-b44b-db6d61112e73","full_name":"Krätschmer, Ilse","orcid":"0000-0002-5636-9259","first_name":"Ilse","last_name":"Krätschmer"},{"full_name":"Smith, Hannah M","first_name":"Hannah M","last_name":"Smith"},{"last_name":"McCartney","first_name":"Daniel L","full_name":"McCartney, Daniel L"},{"full_name":"Bernabeu, Elena","last_name":"Bernabeu","first_name":"Elena"},{"first_name":"Mahdi","last_name":"Mahmoudi","full_name":"Mahmoudi, Mahdi"},{"last_name":"Campbell","first_name":"Archie","full_name":"Campbell, Archie"},{"full_name":"Corley, Janie","first_name":"Janie","last_name":"Corley"},{"full_name":"Harris, Sarah E","first_name":"Sarah E","last_name":"Harris"},{"last_name":"Cox","first_name":"Simon R","full_name":"Cox, Simon R"},{"full_name":"Marioni, Riccardo E","last_name":"Marioni","first_name":"Riccardo E"},{"last_name":"Robinson","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","orcid":"0000-0001-8982-8813"}],"_id":"22972","acknowledgement":"We thank members of the Medical Genomics group at ISTA for their comments, which improved this manuscript. This work was funded by an SNSF Eccellenza Grant to MRR [PCEGP3-181181], and by core funding from the Institute of Science and Technology Austria. We would like to acknowledge the participants and investigators of the Generation Scotland and Lothian Birth Cohort studies. Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006]. Genotyping and methylation typing of the GS: SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” (STRADL) Reference 104036/Z/14/Z]. DNA methylation data for Generation Scotland was also funded by a 2018 NARSAD Young Investigator Grant from the Brain and Behavior Research Foundation [Ref: 27404; awardee: Dr David M Howard] and by a John, Margaret, Alfred and Stewart Sim Fellowship from the Royal College of Physicians of Edinburgh (Awardee: Dr Heather C Whalley). The LBC1936 is supported by the Biotechnology and Biological Sciences Research Council, and the Economic and Social Research Council [BB/W008793/1] (which supports SEH, and JC), Age UK (Disconnected Mind project), the Milton Damerel Trust, the Medical Research Council [G0701120, G1001245, MR/M013111/1, MR/R024065/1] and the University of Edinburgh. Methylation typing of LBC1936 was supported by the Centre for Cognitive Ageing and Cognitive Epidemiology (Pilot Fund award), Age UK, The Wellcome Trust Institutional Strategic Support Fund, The University of Edinburgh, and The University of Queensland. HS is supported by funding from the Wellcome Trust 4-year PhD in Translational Neuroscience [218493/Z/19/Z]. SRC is also supported by a Sir Henry Dale Fellowship jointly funded by Wellcome and the Royal Society [221890/Z/20/Z]. High-performance computing was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp).","PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":6,"publication_identifier":{"eissn":["2635-0041"]},"acknowledged_ssus":[{"_id":"ScienComp"}],"article_number":"vbag231","article_type":"original","oa":1,"file_date_updated":"2026-10-06T12:49:18Z","file":[{"file_id":"23064","success":1,"relation":"main_file","file_name":"2026_BioinformaticsAdvances_Kraetschmer.pdf","file_size":1370368,"date_updated":"2026-10-06T12:49:18Z","content_type":"application/pdf","access_level":"open_access","date_created":"2026-10-06T12:49:18Z","creator":"dernst","checksum":"86849f1b88c47d050be4aa0a40105a97"}],"publication":"Bioinformatics Advances","article_processing_charge":"Yes","fulldoi":"https://doi.org/10.1093/bioadv/vbag231","scopus_import":"1","has_accepted_license":"1","researchdata_availability":"no","month":"09","day":"01","dataavailabilitystatement":"Access to the data is available with appropriate permission from the Generation Scotland Access Committee. Applications should be made to access@generationscotland.org. https://www.ed.ac.uk/lothian-birth-cohorts/data-access-collaboration gives information on the Lothian Birth Cohort data, which are available on request from the Lothian Birth Cohort Study, University of Edinburgh. Data from both cohorts are not publicly available as they contain information that could compromise participant consent and confidentiality.\r\n\r\nSource code is available at https://github.com/medical-genomics-group/MAJA.","issue":"1","publication_status":"published","department":[{"_id":"MaRo"}],"das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"Oxford University Press","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_published":"2026-09-01T00:00:00Z","doi":"10.1093/bioadv/vbag231","external_id":{"pmid":["42761413"]},"corr_author":"1","title":"MAJA: Multivariate Bayesian model for discovery of shared epigenetic pathways across human phenotypes","ddc":["570"],"pmid":1,"date_updated":"2026-10-06T12:50:50Z","oa_version":"Published Version","date_created":"2026-09-22T05:41:01Z","citation":{"ista":"Krätschmer I, Smith HM, McCartney DL, Bernabeu E, Mahmoudi M, Campbell A, Corley J, Harris SE, Cox SR, Marioni RE, Robinson MR. 2026. MAJA: Multivariate Bayesian model for discovery of shared epigenetic pathways across human phenotypes. Bioinformatics Advances. 6(1), vbag231.","ama":"Krätschmer I, Smith HM, McCartney DL, et al. MAJA: Multivariate Bayesian model for discovery of shared epigenetic pathways across human phenotypes. <i>Bioinformatics Advances</i>. 2026;6(1). doi:<a href=\"https://doi.org/10.1093/bioadv/vbag231\">10.1093/bioadv/vbag231</a>","apa":"Krätschmer, I., Smith, H. M., McCartney, D. L., Bernabeu, E., Mahmoudi, M., Campbell, A., … Robinson, M. R. (2026). MAJA: Multivariate Bayesian model for discovery of shared epigenetic pathways across human phenotypes. <i>Bioinformatics Advances</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/bioadv/vbag231\">https://doi.org/10.1093/bioadv/vbag231</a>","short":"I. Krätschmer, H.M. Smith, D.L. McCartney, E. Bernabeu, M. Mahmoudi, A. Campbell, J. Corley, S.E. Harris, S.R. Cox, R.E. Marioni, M.R. Robinson, Bioinformatics Advances 6 (2026).","chicago":"Krätschmer, Ilse, Hannah M Smith, Daniel L McCartney, Elena Bernabeu, Mahdi Mahmoudi, Archie Campbell, Janie Corley, et al. “MAJA: Multivariate Bayesian Model for Discovery of Shared Epigenetic Pathways across Human Phenotypes.” <i>Bioinformatics Advances</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/bioadv/vbag231\">https://doi.org/10.1093/bioadv/vbag231</a>.","mla":"Krätschmer, Ilse, et al. “MAJA: Multivariate Bayesian Model for Discovery of Shared Epigenetic Pathways across Human Phenotypes.” <i>Bioinformatics Advances</i>, vol. 6, no. 1, vbag231, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/bioadv/vbag231\">10.1093/bioadv/vbag231</a>.","ieee":"I. Krätschmer <i>et al.</i>, “MAJA: Multivariate Bayesian model for discovery of shared epigenetic pathways across human phenotypes,” <i>Bioinformatics Advances</i>, vol. 6, no. 1. Oxford University Press, 2026."},"DOAJ_listed":"1","intvolume":"         6","year":"2026","OA_place":"publisher","OA_type":"gold","status":"public","quality_controlled":"1"},{"citation":{"ista":"Dunajova Z, Tasciyan S, Majek J, Merrin J, Jenkins RP, Sahai E, Sixt MK, Hannezo EB. 2026. Substrate heterogeneity promotes cancer cell dissemination through interface roughening. Science Advances. 12(37), eaed0587.","ama":"Dunajova Z, Tasciyan S, Majek J, et al. Substrate heterogeneity promotes cancer cell dissemination through interface roughening. <i>Science Advances</i>. 2026;12(37). doi:<a href=\"https://doi.org/10.1126/sciadv.aed0587\">10.1126/sciadv.aed0587</a>","apa":"Dunajova, Z., Tasciyan, S., Majek, J., Merrin, J., Jenkins, R. P., Sahai, E., … Hannezo, E. B. (2026). Substrate heterogeneity promotes cancer cell dissemination through interface roughening. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.aed0587\">https://doi.org/10.1126/sciadv.aed0587</a>","short":"Z. Dunajova, S. Tasciyan, J. Majek, J. Merrin, R.P. Jenkins, E. Sahai, M.K. Sixt, E.B. Hannezo, Science Advances 12 (2026).","chicago":"Dunajova, Zuzana, Saren Tasciyan, Juraj Majek, Jack Merrin, Robert P. Jenkins, Erik Sahai, Michael K Sixt, and Edouard B Hannezo. “Substrate Heterogeneity Promotes Cancer Cell Dissemination through Interface Roughening.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.aed0587\">https://doi.org/10.1126/sciadv.aed0587</a>.","ieee":"Z. Dunajova <i>et al.</i>, “Substrate heterogeneity promotes cancer cell dissemination through interface roughening,” <i>Science Advances</i>, vol. 12, no. 37. AAAS, 2026.","mla":"Dunajova, Zuzana, et al. “Substrate Heterogeneity Promotes Cancer Cell Dissemination through Interface Roughening.” <i>Science Advances</i>, vol. 12, no. 37, eaed0587, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aed0587\">10.1126/sciadv.aed0587</a>."},"DOAJ_listed":"1","intvolume":"        12","OA_place":"publisher","year":"2026","OA_type":"gold","status":"public","quality_controlled":"1","das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"AAAS","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"related_material":{"record":[{"status":"public","id":"21427","relation":"earlier_version"}]},"date_published":"2026-09-09T00:00:00Z","doi":"10.1126/sciadv.aed0587","title":"Substrate heterogeneity promotes cancer cell dissemination through interface roughening","external_id":{"pmid":["42715298"]},"corr_author":"1","ddc":["570"],"pmid":1,"date_updated":"2026-10-06T11:36:34Z","project":[{"_id":"34d75525-11ca-11ed-8bc3-89b6307fee9d","name":"Motile active matter models of migrating cells and chiral filaments","grant_number":"26360"},{"name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces","_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","grant_number":"101071793"}],"date_created":"2026-09-20T22:01:48Z","oa_version":"Published Version","article_number":"eaed0587","article_type":"original","oa":1,"file":[{"checksum":"79f419b659650a39b3dfa58c782690a8","creator":"dernst","date_updated":"2026-10-06T11:30:48Z","file_size":11691064,"content_type":"application/pdf","access_level":"open_access","date_created":"2026-10-06T11:30:48Z","relation":"main_file","file_name":"2026_ScienceAdv_Dunajova.pdf","file_id":"23062","success":1}],"file_date_updated":"2026-10-06T11:30:48Z","publication":"Science Advances","article_processing_charge":"Yes","scopus_import":"1","fulldoi":"https://doi.org/10.1126/sciadv.aed0587","researchdata_availability":"yes","has_accepted_license":"1","day":"09","month":"09","dataavailabilitystatement":" All data and code needed to evaluate and reproduce the results in the paper are present in the paper and/or the Supplementary Materials and the associated data and code repositories. Source data underlying all figures and supplementary figures have been deposited in a Zenodo repository (DOi: 10.5281/zenodo.21718217) and will be made publicly available upon publication. custom simulation and analysis codes used in this study are available at https://codeocean.com/capsule/1237446/tree. no unique biological materials were generated in this study. Microfluidic mask designs generated for this work are available from the corresponding authors upon reasonable request.","issue":"37","publication_status":"published","department":[{"_id":"EdHa"},{"_id":"MiSi"},{"_id":"GradSch"},{"_id":"AnSa"},{"_id":"NanoFab"}],"abstract":[{"text":"Although studies of tumor invasion have mainly emphasized the evolution of genetic and epigenetic heterogeneity, cellular behaviors also depend on the physical microenvironment. Yet, the tumor microenvironment is both complex and continuously remodeled, making it hard to rigorously test its causal influence on tumor dissemination. Here, we adopted a reductionist approach to studying tumor cell invasion in microengineered environments of tunable patterned geometries. We find that not only the presence of obstacles but more unexpectedly their spatial disorder causes a drastic shift from a collective to a single-cell mode of invasion—comparable in strength to loss of cell-cell adhesion. Combining live-imaging and perturbation experiments with minimal biophysical modeling, we demonstrate that cell dissemination results both from local geometrical constraints and a global integration of spatial disorder over time. We identify generic universality classes of invasion dynamics dependent on environmental geometry, enabling us to identify quantitative physical principles for tumor dissemination.","lang":"eng"}],"type":"journal_article","supplementarymaterial":"no","_id":"22963","PlanS_conform":"1","author":[{"first_name":"Zuzana","last_name":"Dunajova","full_name":"Dunajova, Zuzana","id":"4B39F286-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Saren","last_name":"Tasciyan","orcid":"0000-0003-1671-393X","full_name":"Tasciyan, Saren","id":"4323B49C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Majek","first_name":"Juraj","id":"3e6d9473-f38e-11ec-8ae0-c4e05a8aa9e1","full_name":"Majek, Juraj"},{"last_name":"Merrin","first_name":"Jack","full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609"},{"last_name":"Jenkins","first_name":"Robert P.","full_name":"Jenkins, Robert P."},{"full_name":"Sahai, Erik","first_name":"Erik","last_name":"Sahai"},{"orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K","first_name":"Michael K","last_name":"Sixt"},{"first_name":"Edouard B","last_name":"Hannezo","full_name":"Hannezo, Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561"}],"acknowledgement":"We thank all the members of the Hannezo and Sixt groups for fruitful discussions and t. Kato for advice on the experimental setup. We are also thankful for support from the Scientific Service Units (SSU) of IST Austria through resources provided by the imaging and Optics Facility (iOF) and the Lab Support Facility (lSF). We used chatGPt (GPt- 5,OpenAi, 2025) to make minor grammatical and stylistic revisions to the original manuscript, which was written by us. We carefully reviewed and verified all changes and are solely responsible for all scientific content, data, interpretation, and conclusions. Funding: Z.D. has received funding from the Doctoral Programme of the Austrian Academy of Sciences (OeAW):grant agreement 26360. this work was supported by the European Research council (grant ERC- SyG 101071793 to M.S.). E.S. and R.P.J. are supported by the Francis Crick Institute, which receives its core funding from cancer Research UK (cc2040), the UK Medical Research council(cc2040), and the Wellcome trust (cc2040) and the European Research council (ERC Advanced Grant cAn_ORGAniSe, grant agreement number 101019366).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":12,"publication_identifier":{"eissn":["2375-2548"]},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}]},{"researchdata_availability":"yes","has_accepted_license":"1","day":"17","month":"09","dataavailabilitystatement":"The data that support the findings of this article are openly\r\navailable in Zenodo [10.5281/zenodo.18961933].","issue":"15","department":[{"_id":"MiLe"}],"publication_status":"published","oa":1,"file_date_updated":"2026-10-06T13:19:31Z","file":[{"date_created":"2026-10-06T13:19:31Z","content_type":"application/pdf","access_level":"open_access","date_updated":"2026-10-06T13:19:31Z","file_size":645485,"creator":"dernst","checksum":"784eb7e99c17ecacff5d69c7faf857b6","file_id":"23066","success":1,"file_name":"2026_PhysicalReviewB_Kuliashov.pdf","relation":"main_file"}],"article_number":"154510","article_type":"original","scopus_import":"1","fulldoi":"https://doi.org/10.1103/s1jn-fq4d","publication":"Physical Review B","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":114,"publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"type":"journal_article","abstract":[{"text":"<jats:p>The influence of chiral molecular potentials on phase-coherent transport in superconducting Josephson junctions is investigated. Within a Bogoliubov–de Gennes tight-binding framework, a superconducting-normal-superconducting (SNS) junction functionalized by adsorbed chiral molecules is modeled, where electrostatic gradients generated by the molecules induce spin-orbit coupling in the normal region. The equilibrium charge current-phase relation is found to remain largely insensitive to molecular chirality in symmetric, zero-field configurations. In contrast, the spin-polarized equilibrium current exhibits a pronounced chirality-dependent response, with opposite enantiomers producing distinct and anisotropic spin-polarized Josephson currents. The resulting handedness contrast can be enhanced through control parameters such as molecular orientation and the strength of the induced spin-orbit coupling. The temperature dependence of these currents further shows that the chirality-dependent signatures persist across a range of temperatures well below the superconducting critical temperature. These results identify Josephson interferometry as a phase-sensitive setting for probing chirality-dependent spin structure and highlight spin-polarized superconducting transport as a controlled route toward integrating chiral molecular functionality into superconducting spintronic devices.</jats:p>","lang":"eng"}],"_id":"22976","author":[{"last_name":"Kuliashov","first_name":"Oleg","full_name":"Kuliashov, Oleg"},{"orcid":"0000-0001-6110-2359","id":"9d13b3cb-30a2-11eb-80dc-f772505e8660","full_name":"Cappellaro, Alberto","last_name":"Cappellaro","first_name":"Alberto"},{"full_name":"Millo, Oded","first_name":"Oded","last_name":"Millo"},{"last_name":"Paltiel","first_name":"Yossi","full_name":"Paltiel, Yossi"},{"last_name":"Lemeshko","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802"},{"full_name":"Al Hyder, Ragheed","id":"d1c405be-ae15-11ed-8510-ccf53278162e","last_name":"Al Hyder","first_name":"Ragheed"}],"acknowledgement":"O.K. is funded by the European Union, in the framework of\r\nthe Marie Skłlodowska-Curie Actions-CISSE Doctoral Network, under Grant Agreement No. 101071886. R.A. received\r\nfunding from the Austrian Academy of Sciences (ÖAW),\r\nGrant No. PR1029OEAW03.\r\nViews and opinions expressed are, however, those of the\r\nauthor(s) only and do not necessarily reflect those of the\r\nEuropean Union or the European Research Executive Agency (REA). Neither the European Union nor the granting authority\r\ncan be held responsible for them.","PlanS_conform":"1","arxiv":1,"supplementarymaterial":"yes","OA_place":"publisher","year":"2026","OA_type":"hybrid","quality_controlled":"1","status":"public","citation":{"ista":"Kuliashov O, Cappellaro A, Millo O, Paltiel Y, Lemeshko M, Al Hyder R. 2026. Supercurrents in Josephson junctions with chiral molecular potentials. Physical Review B. 114(15), 154510.","chicago":"Kuliashov, Oleg, Alberto Cappellaro, Oded Millo, Yossi Paltiel, Mikhail Lemeshko, and Ragheed Al Hyder. “Supercurrents in Josephson Junctions with Chiral Molecular Potentials.” <i>Physical Review B</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/s1jn-fq4d\">https://doi.org/10.1103/s1jn-fq4d</a>.","short":"O. Kuliashov, A. Cappellaro, O. Millo, Y. Paltiel, M. Lemeshko, R. Al Hyder, Physical Review B 114 (2026).","mla":"Kuliashov, Oleg, et al. “Supercurrents in Josephson Junctions with Chiral Molecular Potentials.” <i>Physical Review B</i>, vol. 114, no. 15, 154510, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/s1jn-fq4d\">10.1103/s1jn-fq4d</a>.","ieee":"O. Kuliashov, A. Cappellaro, O. Millo, Y. Paltiel, M. Lemeshko, and R. Al Hyder, “Supercurrents in Josephson junctions with chiral molecular potentials,” <i>Physical Review B</i>, vol. 114, no. 15. American Physical Society, 2026.","ama":"Kuliashov O, Cappellaro A, Millo O, Paltiel Y, Lemeshko M, Al Hyder R. Supercurrents in Josephson junctions with chiral molecular potentials. <i>Physical Review B</i>. 2026;114(15). doi:<a href=\"https://doi.org/10.1103/s1jn-fq4d\">10.1103/s1jn-fq4d</a>","apa":"Kuliashov, O., Cappellaro, A., Millo, O., Paltiel, Y., Lemeshko, M., &#38; Al Hyder, R. (2026). Supercurrents in Josephson junctions with chiral molecular potentials. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/s1jn-fq4d\">https://doi.org/10.1103/s1jn-fq4d</a>"},"intvolume":"       114","title":"Supercurrents in Josephson junctions with chiral molecular potentials","external_id":{"arxiv":["2603.10925"]},"corr_author":"1","date_published":"2026-09-17T00:00:00Z","doi":"10.1103/s1jn-fq4d","project":[{"grant_number":"12078","name":"Polarons in Lead Halide Perovskites","_id":"8fa7db46-16d5-11f0-9cad-917600954daf"}],"oa_version":"Published Version","date_created":"2026-09-22T05:47:09Z","ddc":["530"],"date_updated":"2026-10-06T13:25:35Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"das_tickbox":"1","publisher":"American Physical Society","language":[{"iso":"eng"}]},{"citation":{"ista":"Lee W, Shi W, Kwon J, Low J, Wei S, Yin X, Campos LM, Venkataraman L. 2026. Redox-driven antiaromaticity enables multistate conductancein 1D topological insulators. Journal of the AmericanChemical Society. 148(37), 40536–40542.","apa":"Lee, W., Shi, W., Kwon, J., Low, J., Wei, S., Yin, X., … Venkataraman, L. (2026). Redox-driven antiaromaticity enables multistate conductancein 1D topological insulators. <i>Journal of the AmericanChemical Society</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.6c15721\">https://doi.org/10.1021/jacs.6c15721</a>","ama":"Lee W, Shi W, Kwon J, et al. Redox-driven antiaromaticity enables multistate conductancein 1D topological insulators. <i>Journal of the AmericanChemical Society</i>. 2026;148(37):40536–40542. doi:<a href=\"https://doi.org/10.1021/jacs.6c15721\">10.1021/jacs.6c15721</a>","mla":"Lee, Woojung, et al. “Redox-Driven Antiaromaticity Enables Multistate Conductancein 1D Topological Insulators.” <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 37, American Chemical Society, 2026, pp. 40536–40542, doi:<a href=\"https://doi.org/10.1021/jacs.6c15721\">10.1021/jacs.6c15721</a>.","ieee":"W. Lee <i>et al.</i>, “Redox-driven antiaromaticity enables multistate conductancein 1D topological insulators,” <i>Journal of the AmericanChemical Society</i>, vol. 148, no. 37. American Chemical Society, pp. 40536–40542, 2026.","chicago":"Lee, Woojung, Wanzhuo Shi, Junho Kwon, Jonathan Low, Sujun Wei, Xiaodong Yin, Luis M. Campos, and Latha Venkataraman. “Redox-Driven Antiaromaticity Enables Multistate Conductancein 1D Topological Insulators.” <i>Journal of the AmericanChemical Society</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/jacs.6c15721\">https://doi.org/10.1021/jacs.6c15721</a>.","short":"W. Lee, W. Shi, J. Kwon, J. Low, S. Wei, X. Yin, L.M. Campos, L. Venkataraman, Journal of the AmericanChemical Society 148 (2026) 40536–40542."},"intvolume":"       148","OA_type":"hybrid","year":"2026","OA_place":"publisher","quality_controlled":"1","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publisher":"American Chemical Society","language":[{"iso":"eng"}],"das_tickbox":"0","corr_author":"1","title":"Redox-driven antiaromaticity enables multistate conductancein 1D topological insulators","doi":"10.1021/jacs.6c15721","date_published":"2026-09-07T00:00:00Z","date_created":"2026-09-22T05:46:30Z","oa_version":"Published Version","date_updated":"2026-10-06T13:14:11Z","ddc":["540"],"file_date_updated":"2026-10-06T13:10:49Z","file":[{"creator":"dernst","checksum":"91f85ec18e571a602d2fec942825c9d2","date_updated":"2026-10-06T13:10:49Z","file_size":3646582,"content_type":"application/pdf","access_level":"open_access","date_created":"2026-10-06T13:10:49Z","relation":"main_file","file_name":"2026_JACS_LeeWoojung.pdf","file_id":"23065","success":1}],"oa":1,"article_type":"original","fulldoi":"https://doi.org/10.1021/jacs.6c15721","scopus_import":"1","article_processing_charge":"Yes (via OA deal)","publication":"Journal of the AmericanChemical Society","month":"09","day":"07","researchdata_availability":"no","has_accepted_license":"1","publication_status":"published","department":[{"_id":"LaVe"}],"issue":"37","type":"journal_article","abstract":[{"text":"Conjugated molecules with diradical character have emerged as promising building blocks for high-conductance single-molecule electronics because of their behavior as 1D topological insulators. However, the impact of antiaromaticity on these radical-based edge states has not been explored. Here, we introduce thiophene-based molecular wires that exhibit intrinsic diradical character in their ground state under ambient conditions and systematically investigate how their conductance responds to changes in aromaticity upon the oxidation of fluorene-based flanking moieties. Using scanning tunneling microscopy-based break junction (STM-BJ) techniques, we show that the conductance increases with molecular length in the neutral state, supporting one-dimensional topological behavior. We further examine the effect of oxidation on conductance through three complementary methods, revealing substantial conductance enhancements that we attribute to an increase in the antiaromatic character of the wires. Together, these findings establish a rational design strategy for highly conducting, electrochemically switchable molecular junctions, with implications for single-molecule electronics.","lang":"eng"}],"_id":"22975","acknowledgement":"This work was supported in part by the National Science Foundation under grant DMR-2241180 and the Institute of Science and Technology Austria. L.M.C. thanks the National Science Foundation for funding under award DMR-2453907. Open access funding provided by Institute of Science and Technology Austria.","author":[{"full_name":"Lee, Woojung","first_name":"Woojung","last_name":"Lee"},{"full_name":"Shi, Wanzhuo","id":"a3010425-87c8-11f0-8106-bec32bea74da","last_name":"Shi","first_name":"Wanzhuo"},{"last_name":"Kwon","first_name":"Junho","full_name":"Kwon, Junho"},{"last_name":"Low","first_name":"Jonathan","full_name":"Low, Jonathan"},{"first_name":"Sujun","last_name":"Wei","full_name":"Wei, Sujun"},{"last_name":"Yin","first_name":"Xiaodong","full_name":"Yin, Xiaodong"},{"full_name":"Campos, Luis M.","last_name":"Campos","first_name":"Luis M."},{"orcid":"0000-0002-6957-6089","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf","full_name":"Venkataraman, Latha","first_name":"Latha","last_name":"Venkataraman"}],"PlanS_conform":"1","supplementarymaterial":"yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["0002-7863"],"eissn":["1520-5126"]},"page":"40536–40542","volume":148},{"OA_place":"publisher","year":"2026","OA_type":"hybrid","quality_controlled":"1","status":"public","citation":{"ista":"Zhang S, Zeng G, Yu J, Horta S, Lu X, Sun Q, Ren Y, Ibáñez M, Llorca J, Biendicho JJ, Arbiol J, Ci L, Cabot A. 2026. Reinforced poly(ionic liquid)-in-salt electrolytes for highly stable solid-state Lithium metal batteries. Advanced Fiber Materials.","ama":"Zhang S, Zeng G, Yu J, et al. Reinforced poly(ionic liquid)-in-salt electrolytes for highly stable solid-state Lithium metal batteries. <i>Advanced Fiber Materials</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s42765-026-00775-2\">10.1007/s42765-026-00775-2</a>","apa":"Zhang, S., Zeng, G., Yu, J., Horta, S., Lu, X., Sun, Q., … Cabot, A. (2026). Reinforced poly(ionic liquid)-in-salt electrolytes for highly stable solid-state Lithium metal batteries. <i>Advanced Fiber Materials</i>. Springer. <a href=\"https://doi.org/10.1007/s42765-026-00775-2\">https://doi.org/10.1007/s42765-026-00775-2</a>","short":"S. Zhang, G. Zeng, J. Yu, S. Horta, X. Lu, Q. Sun, Y. Ren, M. Ibáñez, J. Llorca, J.J. Biendicho, J. Arbiol, L. Ci, A. Cabot, Advanced Fiber Materials (2026).","chicago":"Zhang, Shengnan, Guifang Zeng, Jing Yu, Sharona Horta, Xuan Lu, Qing Sun, Yuchuan Ren, et al. “Reinforced Poly(Ionic Liquid)-in-Salt Electrolytes for Highly Stable Solid-State Lithium Metal Batteries.” <i>Advanced Fiber Materials</i>. Springer, 2026. <a href=\"https://doi.org/10.1007/s42765-026-00775-2\">https://doi.org/10.1007/s42765-026-00775-2</a>.","mla":"Zhang, Shengnan, et al. “Reinforced Poly(Ionic Liquid)-in-Salt Electrolytes for Highly Stable Solid-State Lithium Metal Batteries.” <i>Advanced Fiber Materials</i>, Springer, 2026, doi:<a href=\"https://doi.org/10.1007/s42765-026-00775-2\">10.1007/s42765-026-00775-2</a>.","ieee":"S. Zhang <i>et al.</i>, “Reinforced poly(ionic liquid)-in-salt electrolytes for highly stable solid-state Lithium metal batteries,” <i>Advanced Fiber Materials</i>. Springer, 2026."},"title":"Reinforced poly(ionic liquid)-in-salt electrolytes for highly stable solid-state Lithium metal batteries","date_published":"2026-09-08T00:00:00Z","doi":"10.1007/s42765-026-00775-2","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"oa_version":"Published Version","date_created":"2026-09-20T22:01:49Z","ddc":["540"],"date_updated":"2026-10-06T11:57:17Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"Springer","has_accepted_license":"1","researchdata_availability":"upon request","month":"09","day":"08","dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author upon reasonable request.","department":[{"_id":"MaIb"}],"publication_status":"epub_ahead","oa":1,"article_type":"original","main_file_link":[{"url":"https://doi.org/10.1007/s42765-026-00775-2","open_access":"1"}],"fulldoi":"https://doi.org/10.1007/s42765-026-00775-2","scopus_import":"1","publication":"Advanced Fiber Materials","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2524-7921"],"eissn":["2524-793X"]},"type":"journal_article","abstract":[{"lang":"eng","text":"Solid-state polymer electrolytes (SPEs) are promising for high-safety, high-energy-density lithium metal batteries, but their adoption is limited by low room-temperature ionic conductivity and insufficient mechanical robustness. This study reports an improved SPE architecture consisting of a three-dimensional (3D) polyacrylonitrile (PAN)–Li6.4La3Zr1.4Ta0.6O12 (LLZTO) fibrous skeleton infused with a polymer electrolyte ionic liquid (PIL), which promotes lithium-salt dissociation, accelerates Li+ transport, and enhances mechanical strength. The resulting SPE achieves an ionic conductivity of up to 0.51 mS cm−1. Li|Li symmetric cells using a 40-µm-thick SPE cycle stably for 2500 h at 0.2 mA cm−2 with a low overpotential of 30 mV. In Li|LiFePO4 (LFP) full cells, the electrolyte enables 86.8% capacity retention after 1000 cycles at 0.5 C and maintains stable operation at 130 °C. Flexible pouch-cell tests further confirm improved safety and durability under harsh conditions, highlighting the potential of this SPE design for high-voltage lithium metal batteries."}],"_id":"22966","PlanS_conform":"1","author":[{"first_name":"Shengnan","last_name":"Zhang","full_name":"Zhang, Shengnan"},{"full_name":"Zeng, Guifang","first_name":"Guifang","last_name":"Zeng"},{"first_name":"Jing","last_name":"Yu","full_name":"Yu, Jing"},{"full_name":"Horta, Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","first_name":"Sharona"},{"last_name":"Lu","first_name":"Xuan","full_name":"Lu, Xuan"},{"full_name":"Sun, Qing","last_name":"Sun","first_name":"Qing"},{"last_name":"Ren","first_name":"Yuchuan","full_name":"Ren, Yuchuan"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","first_name":"Maria"},{"full_name":"Llorca, Jordi","first_name":"Jordi","last_name":"Llorca"},{"first_name":"Jordi Jacas","last_name":"Biendicho","full_name":"Biendicho, Jordi Jacas"},{"full_name":"Arbiol, Jordi","last_name":"Arbiol","first_name":"Jordi"},{"last_name":"Ci","first_name":"Lijie","full_name":"Ci, Lijie"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"}],"acknowledgement":"This work was financially supported by the Generalitat de Catalunya (2021SGR01581), the Major Innovation Projects for Integrating Science, Education & Industry of Qilu University of Technology (Shandong Academy of Sciences) (Grant No. 2025ZDZX19) and the China Postdoctoral Science Foundation (Grant No. 2026M790106). ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/https://doi.org/10.13039/501100011033/ and by “ERDF A way of making Europe”, by the “European Union”. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD program. JY has received funding from the CSC-UAB PhD scholarship program. ISTA co-authors acknowledge funding from the Werner Siemens Foundation. Authors acknowledge the use of instrumentation as well as the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member of e-DREAM [51]. JL is a Serra Húnter Fellow and is grateful to the Academia Excellence program (Generalitat de Catalunya) and to projects MICIU/FEDER PID2024-156765OB-C21 and Maria de Maeztu Units of Excellence Programme CEX2023-001300-M funded by MCIN/AEI https://doi.org/10.13039/501100011033.Open Access funding provided by CERCA through the CRUE-CSIC agreement with Springer Nature.","supplementarymaterial":"yes"},{"department":[{"_id":"PaSc"}],"publication_status":"epub_ahead","dataavailabilitystatement":"No data was used for the research described in the article.","day":"01","month":"09","has_accepted_license":"1","researchdata_availability":"no","article_processing_charge":"Yes (via OA deal)","publication":"Progress in Nuclear Magnetic Resonance Spectroscopy","fulldoi":"https://doi.org/10.1016/j.pnmrs.2026.101615","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.pnmrs.2026.101615"}],"article_type":"original","article_number":"101615","oa":1,"publication_identifier":{"issn":["0079-6565"],"eissn":["1873-3301"]},"volume":"156-157","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","author":[{"full_name":"Tatman, Benjamin","id":"71cda2f3-e604-11ee-a1df-da10587eda3f","first_name":"Benjamin","last_name":"Tatman"},{"first_name":"Paul","last_name":"Schanda","orcid":"0000-0002-9350-7606","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","full_name":"Schanda, Paul"}],"_id":"22974","acknowledgement":"We thank the Austrian Science Fund (FWF, project number 10.55776/I5812) for support. We are grateful to Petra Rovó (ISTA) for many insightful discussions.","abstract":[{"lang":"eng","text":"Far from being static structures, it is now well accepted that proteins are highly dynamic entities even in the solid state. Here, we review recent progress in application of magic-angle spinning (MAS) NMR for studying the site-specific dynamics of proteins, as assessed using spin-relaxation and measurement of anisotropic spin interactions. We focus on the types of experimental data that are available, and how best to access the information which is provided by these experimental measurements; in particular, we provide a retrospective on the field in light of recent advances in analytical methodologies, which have led to a slow paradigm shift in how we interpret relaxation rate constant measurements made in the solid state."}],"type":"journal_article","quality_controlled":"1","status":"public","OA_type":"hybrid","year":"2026","OA_place":"publisher","citation":{"ieee":"B. Tatman and P. Schanda, “Quantifying fast protein dynamics by magic-angle spinning NMR: Progress in experimental and analytical approaches,” <i>Progress in Nuclear Magnetic Resonance Spectroscopy</i>, vol. 156–157. Elsevier, 2026.","mla":"Tatman, Benjamin, and Paul Schanda. “Quantifying Fast Protein Dynamics by Magic-Angle Spinning NMR: Progress in Experimental and Analytical Approaches.” <i>Progress in Nuclear Magnetic Resonance Spectroscopy</i>, vol. 156–157, 101615, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.pnmrs.2026.101615\">10.1016/j.pnmrs.2026.101615</a>.","chicago":"Tatman, Benjamin, and Paul Schanda. “Quantifying Fast Protein Dynamics by Magic-Angle Spinning NMR: Progress in Experimental and Analytical Approaches.” <i>Progress in Nuclear Magnetic Resonance Spectroscopy</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.pnmrs.2026.101615\">https://doi.org/10.1016/j.pnmrs.2026.101615</a>.","short":"B. Tatman, P. Schanda, Progress in Nuclear Magnetic Resonance Spectroscopy 156–157 (2026).","apa":"Tatman, B., &#38; Schanda, P. (2026). Quantifying fast protein dynamics by magic-angle spinning NMR: Progress in experimental and analytical approaches. <i>Progress in Nuclear Magnetic Resonance Spectroscopy</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.pnmrs.2026.101615\">https://doi.org/10.1016/j.pnmrs.2026.101615</a>","ama":"Tatman B, Schanda P. Quantifying fast protein dynamics by magic-angle spinning NMR: Progress in experimental and analytical approaches. <i>Progress in Nuclear Magnetic Resonance Spectroscopy</i>. 2026;156-157. doi:<a href=\"https://doi.org/10.1016/j.pnmrs.2026.101615\">10.1016/j.pnmrs.2026.101615</a>","ista":"Tatman B, Schanda P. 2026. Quantifying fast protein dynamics by magic-angle spinning NMR: Progress in experimental and analytical approaches. Progress in Nuclear Magnetic Resonance Spectroscopy. 156–157, 101615."},"date_updated":"2026-10-06T13:00:47Z","ddc":["540"],"date_created":"2026-09-22T05:44:22Z","oa_version":"Published Version","project":[{"_id":"eb9c82eb-77a9-11ec-83b8-aadd536561cf","name":"AlloSpace. The emergence and mechanisms of allostery","grant_number":"I05812"}],"keyword":["Solid-state NMR","Protein dynamics","Magic-angle spinning"],"doi":"10.1016/j.pnmrs.2026.101615","date_published":"2026-09-01T00:00:00Z","corr_author":"1","title":"Quantifying fast protein dynamics by magic-angle spinning NMR: Progress in experimental and analytical approaches","language":[{"iso":"eng"}],"publisher":"Elsevier","das_tickbox":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"doi":"10.1145/3843232","date_published":"2026-09-01T00:00:00Z","corr_author":"1","title":"Distortion of multi-winner elections on the line metric: The polar comparison rule","date_updated":"2026-10-06T12:38:17Z","ddc":["000"],"oa_version":"Published Version","date_created":"2026-09-22T05:37:33Z","language":[{"iso":"eng"}],"publisher":"ACM","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"OA_type":"gold","year":"2026","OA_place":"publisher","status":"public","quality_controlled":"1","citation":{"chicago":"Babashah, Negar, Hasti Karimi, Masoud Seddighin, and Golnoosh Shahkarami. “Distortion of Multi-Winner Elections on the Line Metric: The Polar Comparison Rule.” <i>ACM Transactions on Economics and Computation</i>. ACM, 2026. <a href=\"https://doi.org/10.1145/3843232\">https://doi.org/10.1145/3843232</a>.","short":"N. Babashah, H. Karimi, M. Seddighin, G. Shahkarami, ACM Transactions on Economics and Computation (2026).","mla":"Babashah, Negar, et al. “Distortion of Multi-Winner Elections on the Line Metric: The Polar Comparison Rule.” <i>ACM Transactions on Economics and Computation</i>, 3843232, ACM, 2026, doi:<a href=\"https://doi.org/10.1145/3843232\">10.1145/3843232</a>.","ieee":"N. Babashah, H. Karimi, M. Seddighin, and G. Shahkarami, “Distortion of multi-winner elections on the line metric: The polar comparison rule,” <i>ACM Transactions on Economics and Computation</i>. ACM, 2026.","ama":"Babashah N, Karimi H, Seddighin M, Shahkarami G. Distortion of multi-winner elections on the line metric: The polar comparison rule. <i>ACM Transactions on Economics and Computation</i>. 2026. doi:<a href=\"https://doi.org/10.1145/3843232\">10.1145/3843232</a>","apa":"Babashah, N., Karimi, H., Seddighin, M., &#38; Shahkarami, G. (2026). Distortion of multi-winner elections on the line metric: The polar comparison rule. <i>ACM Transactions on Economics and Computation</i>. ACM. <a href=\"https://doi.org/10.1145/3843232\">https://doi.org/10.1145/3843232</a>","ista":"Babashah N, Karimi H, Seddighin M, Shahkarami G. 2026. Distortion of multi-winner elections on the line metric: The polar comparison rule. ACM Transactions on Economics and Computation., 3843232."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2167-8375"],"eissn":["2167-8383"]},"abstract":[{"lang":"eng","text":"We study the problem of minimizing metric distortion in multi-winner elections, where a committee of size k is selected from a set of candidates based on voters’ ordinal preferences. We assume that voters and candidates are embedded on a line metric, and social cost is determined by the underlying metric distances.\r\nThe distortion of a voting rule is the worst-case ratio between the social cost of the elected committee and an optimal committee. Previous work has focused on the q-cost model, in which a voter’s cost is given by the distance to their qth closest committee member. Here, we study the additive cost, where a voter’s cost is the sum of distances to all committee members.\r\nWe introduce the Polar Comparison Rule and analyze its distortion under utilitarian additive cost. We show that it achieves a distortion upper bound of almost 2.33 for all committee sizes k > 4, improving upon the previously best-known upper bound of 3. Moreover, for k = 2 and k = 3, we establish tight distortion bounds of 2.41 and 2.33, respectively. We also derive lower bounds that depend on the parity of k and analyze the behavior of distortion for small and large committee sizes. Finally, we extend our results to the egalitarian additive cost."}],"type":"journal_article","_id":"22971","PlanS_conform":"1","author":[{"orcid":"0009-0007-0203-9725","id":"95f4864e-6ec9-11f0-b3f6-b8422c64859e","full_name":"Babashah, Negar","first_name":"Negar","last_name":"Babashah"},{"last_name":"Karimi","first_name":"Hasti","full_name":"Karimi, Hasti"},{"first_name":"Masoud","last_name":"Seddighin","full_name":"Seddighin, Masoud"},{"last_name":"Shahkarami","first_name":"Golnoosh","full_name":"Shahkarami, Golnoosh"}],"month":"09","day":"01","has_accepted_license":"1","publication_status":"epub_ahead","department":[{"_id":"GradSch"}],"article_type":"original","article_number":"3843232","oa":1,"article_processing_charge":"Yes","publication":"ACM Transactions on Economics and Computation","fulldoi":"https://doi.org/10.1145/3843232","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1145/3843232"}]},{"acknowledgement":"This work was supported in part by the SAFEXPLAIN project under Grant 101069595.\r\nThis work was supported in part by the ROBOCONS project under Grant 101235566, from the European Union‘s HORIZON-CL5-2024-D4-02 research and innovation programme.\r\nThis work was supported in part by the Austrian Science Fund (FWF) - Reference 10.55776/COE12.\r\nThis work was supported in part by the Intelligent Systems for Industrial Systems research group of Mondragon Unibertsitatea - Reference IT1870-26. Department of Science, Universities and Innovation of the Basque Government.\r\nThis work was supported in part by the European Research Council under Grant No.: ERC-2020-AdG 101020093. This work was also supported by the ISTA Responsible AI Program, made possible through the support of Garrett Camp and the Camp Foundation .","_id":"22999","author":[{"last_name":"Odriozola-Olalde","first_name":"Haritz","full_name":"Odriozola-Olalde, Haritz"},{"last_name":"Cano Cordoba","first_name":"Filip","orcid":"0000-0002-0783-904X","full_name":"Cano Cordoba, Filip","id":"708cad98-e86a-11ef-8098-bdae2d7c6af1"},{"last_name":"Könighofer","first_name":"Bettina","full_name":"Könighofer, Bettina"},{"last_name":"Arana-Arexolaleiba","first_name":"Nestor","full_name":"Arana-Arexolaleiba, Nestor"},{"last_name":"Zamalloa","first_name":"Maider","full_name":"Zamalloa, Maider"},{"first_name":"Jon","last_name":"Perez-Cerrolaza","full_name":"Perez-Cerrolaza, Jon"}],"PlanS_conform":"1","supplementarymaterial":"no","type":"journal_article","abstract":[{"text":"The safety of Reinforcement Learning (RL)-based controllers has become a prominent research area in recent years, with various approaches being proposed to address this critical issue. Runtime Safety Assurance (RSA) methods for RL, such as Shielded RL, provide formal safety guarantees by preventing agents from taking unsafe actions and suggesting safe alternatives when necessary. However, previous surveys and reviews on RSA for RL have not thoroughly analysed the challenges and applications within the industrial sector. This study builds on existing state-of-the-art research on Shielded RL methods, emphasising its contributions to industrial applications and offering a domain-specific categorisation. This categorisation highlights the primary industrial domains utilising Shielded RL, detailing the optimised functions achieved by RL and the safety functions ensured by the shield. Additionally, the study presents a categorisation based on environmental features, enabling readers to assess the complexity of the problems addressed by the techniques studied. The shield’s attributes are analysed for each work, identifying key trends in their application, including their adaptability to new scenarios. Finally, a basic categorisation model for Shielded RL approaches, grounded in industrial safety standards, is introduced. This model serves as a baseline for future studies aiming to evaluate the maturity level of the works reviewed.","lang":"eng"}],"volume":32,"publication_identifier":{"issn":["2667-3053"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","fulldoi":"https://doi.org/10.1016/j.iswa.2026.200729","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1016/j.iswa.2026.200729","open_access":"1"}],"publication":"Intelligent Systems with Applications","article_processing_charge":"Yes","oa":1,"article_number":"200729","article_type":"review","dataavailabilitystatement":"No data was used for the research described in the article.","department":[{"_id":"ToHe"}],"publication_status":"epub_ahead","researchdata_availability":"no","has_accepted_license":"1","month":"09","day":"18","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"Elsevier","project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093"}],"keyword":["Reinforcement learning","Runtime safety assurance","Shield","Safety","Industrial application"],"oa_version":"Published Version","date_created":"2026-09-27T22:01:51Z","ddc":["000"],"date_updated":"2026-10-07T06:25:37Z","title":"Shielded reinforcement learning for industrial applications: A systematic literature survey","corr_author":"1","date_published":"2026-09-18T00:00:00Z","doi":"10.1016/j.iswa.2026.200729","intvolume":"        32","DOAJ_listed":"1","citation":{"ista":"Odriozola-Olalde H, Cano Cordoba F, Könighofer B, Arana-Arexolaleiba N, Zamalloa M, Perez-Cerrolaza J. 2026. Shielded reinforcement learning for industrial applications: A systematic literature survey. Intelligent Systems with Applications. 32, 200729.","apa":"Odriozola-Olalde, H., Cano Cordoba, F., Könighofer, B., Arana-Arexolaleiba, N., Zamalloa, M., &#38; Perez-Cerrolaza, J. (2026). Shielded reinforcement learning for industrial applications: A systematic literature survey. <i>Intelligent Systems with Applications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.iswa.2026.200729\">https://doi.org/10.1016/j.iswa.2026.200729</a>","ama":"Odriozola-Olalde H, Cano Cordoba F, Könighofer B, Arana-Arexolaleiba N, Zamalloa M, Perez-Cerrolaza J. Shielded reinforcement learning for industrial applications: A systematic literature survey. <i>Intelligent Systems with Applications</i>. 2026;32. doi:<a href=\"https://doi.org/10.1016/j.iswa.2026.200729\">10.1016/j.iswa.2026.200729</a>","ieee":"H. Odriozola-Olalde, F. Cano Cordoba, B. Könighofer, N. Arana-Arexolaleiba, M. Zamalloa, and J. Perez-Cerrolaza, “Shielded reinforcement learning for industrial applications: A systematic literature survey,” <i>Intelligent Systems with Applications</i>, vol. 32. Elsevier, 2026.","mla":"Odriozola-Olalde, Haritz, et al. “Shielded Reinforcement Learning for Industrial Applications: A Systematic Literature Survey.” <i>Intelligent Systems with Applications</i>, vol. 32, 200729, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.iswa.2026.200729\">10.1016/j.iswa.2026.200729</a>.","short":"H. Odriozola-Olalde, F. Cano Cordoba, B. Könighofer, N. Arana-Arexolaleiba, M. Zamalloa, J. Perez-Cerrolaza, Intelligent Systems with Applications 32 (2026).","chicago":"Odriozola-Olalde, Haritz, Filip Cano Cordoba, Bettina Könighofer, Nestor Arana-Arexolaleiba, Maider Zamalloa, and Jon Perez-Cerrolaza. “Shielded Reinforcement Learning for Industrial Applications: A Systematic Literature Survey.” <i>Intelligent Systems with Applications</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.iswa.2026.200729\">https://doi.org/10.1016/j.iswa.2026.200729</a>."},"status":"public","quality_controlled":"1","ec_funded":1,"OA_place":"publisher","year":"2026","OA_type":"gold"},{"language":[{"iso":"eng"}],"das_tickbox":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"related_material":{"record":[{"status":"public","id":"21968","relation":"earlier_version"}]},"doi":"10.1016/j.tpb.2026.09.001","date_published":"2026-09-17T00:00:00Z","corr_author":"1","external_id":{"pmid":["42722132"],"biorxivid":["10.1101/2025.04.09.647826"]},"title":"Sign epistasis extends the effects of balancing selection on genetic diversity","pmid":1,"date_updated":"2026-10-07T06:38:02Z","ddc":["500","570"],"date_created":"2026-09-27T22:01:51Z","oa_version":"Published Version","keyword":["Sign epistasis","Balancing selection","Within-population genetic variation"],"project":[{"grant_number":"26293","name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8"}],"citation":{"short":"K. Khudiakova, N.H. Barton, G. Arnqvist, Theoretical Population Biology 172 (2026) 48–55.","chicago":"Khudiakova, Kseniia, Nicholas H Barton, and Göran Arnqvist. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>Theoretical Population Biology</i>, 2026. <a href=\"https://doi.org/10.1016/j.tpb.2026.09.001\">https://doi.org/10.1016/j.tpb.2026.09.001</a>.","ieee":"K. Khudiakova, N. H. Barton, and G. Arnqvist, “Sign epistasis extends the effects of balancing selection on genetic diversity,” <i>Theoretical Population Biology</i>, vol. 172. pp. 48–55, 2026.","mla":"Khudiakova, Kseniia, et al. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>Theoretical Population Biology</i>, vol. 172, 2026, pp. 48–55, doi:<a href=\"https://doi.org/10.1016/j.tpb.2026.09.001\">10.1016/j.tpb.2026.09.001</a>.","ama":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. <i>Theoretical Population Biology</i>. 2026;172:48-55. doi:<a href=\"https://doi.org/10.1016/j.tpb.2026.09.001\">10.1016/j.tpb.2026.09.001</a>","apa":"Khudiakova, K., Barton, N. H., &#38; Arnqvist, G. (2026). Sign epistasis extends the effects of balancing selection on genetic diversity. <i>Theoretical Population Biology</i>. <a href=\"https://doi.org/10.1016/j.tpb.2026.09.001\">https://doi.org/10.1016/j.tpb.2026.09.001</a>","ista":"Khudiakova K, Barton NH, Arnqvist G. 2026. Sign epistasis extends the effects of balancing selection on genetic diversity. Theoretical Population Biology. 172, 48–55."},"intvolume":"       172","biorxivid":1,"OA_type":"hybrid","year":"2026","OA_place":"publisher","quality_controlled":"1","status":"public","abstract":[{"lang":"eng","text":"Balancing selection, a form of selection that maintains genetic diversity, is difficult to detect, and the importance of balancing selection for the maintenance of genetic variation may be larger than often assumed. We model the possibility that the diversity-promoting effects of balancing selection extend to other loci that show sign epistasis with a locus under balancing selection. Rather than focusing on overdominance, as was done in previous efforts, we explore the effects of negative frequency dependence and show that this has important effects on the conditions under which the diversity-promoting effect of epistasis can occur in diploids. Our results show that not only recombination rate but also the dominance of sign epistasis are key parameters that determine the maintenance of polymorphism beyond the locus under direct balancing selection. We suggest that the effect we explore may play a significant role, especially when balancing selection acts on major effect loci."}],"type":"journal_article","supplementarymaterial":"yes","PlanS_conform":"1","_id":"22998","acknowledgement":"This work was funded by grants from the Swedish Research Council (2023-03730 to G.A.) and the DOC fellowship from the Austrian Academy of Science (26293 to K.K.). We thank L. Rowe for valuable discussions.","author":[{"last_name":"Khudiakova","first_name":"Kseniia","orcid":"0000-0002-6246-1465","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","full_name":"Khudiakova, Kseniia"},{"last_name":"Barton","first_name":"Nicholas H","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Göran","last_name":"Arnqvist","full_name":"Arnqvist, Göran"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"48-55","publication_identifier":{"issn":["0040-5809"],"eissn":["1096-0325"]},"volume":172,"article_type":"original","oa":1,"article_processing_charge":"Yes (via OA deal)","publication":"Theoretical Population Biology","fulldoi":"https://doi.org/10.1016/j.tpb.2026.09.001","main_file_link":[{"url":"https://doi.org/10.1016/j.tpb.2026.09.001","open_access":"1"}],"scopus_import":"1","day":"17","month":"09","has_accepted_license":"1","researchdata_availability":"no","publication_status":"epub_ahead","department":[{"_id":"JaMa"},{"_id":"GradSch"},{"_id":"NiBa"}],"dataavailabilitystatement":"The Python code used for the numerical analyses is available online at https://github.com/khudyakovaks/Sign-epistasis-extends-the-effects-of-balancing-selection-on-genetic-diversity."},{"oa":1,"fulldoi":"https://doi.org/10.1101/2025.04.09.647826","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.04.09.647826"}],"article_processing_charge":"No","publication":"bioRxiv","month":"04","day":"23","publication_status":"draft","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"type":"preprint","abstract":[{"text":"Balancing selection, a form of selection that maintains genetic diversity, is difficult to detect, and the importance of balancing selection for the maintenance of genetic variation may be larger than often assumed. We model the possibility that the diversity-promoting effects of balancing selection extend to other loci that show sign epistasis with a locus under balancing selection. Rather than focusing on overdominance, as was done in previous efforts, we explore the effects of negative frequency dependence and show that this has important effects on the conditions under which the diversity-promoting effect of epistasis can occur in diploids. Our results show that not only recombination rate but also the dominance of sign epistasis are key parameters that determine the maintenance of polymorphism beyond the locus under direct balancing selection. We suggest that the effect we explore may play a significant role, especially when balancing selection acts on major effect loci.","lang":"eng"}],"author":[{"orcid":"0000-0002-6246-1465","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","full_name":"Khudiakova, Kseniia","last_name":"Khudiakova","first_name":"Kseniia"},{"last_name":"Barton","first_name":"Nicholas H","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Arnqvist, Goran","first_name":"Goran","last_name":"Arnqvist"}],"_id":"21968","acknowledgement":"This work was funded by grants from the Swedish Research Council (2023-03730 to G.A.) and the DOC fellowship from the Austrian Academy of Science (26293 to K.K.).","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","citation":{"apa":"Khudiakova, K., Barton, N. H., &#38; Arnqvist, G. (n.d.). Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>","ama":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>","ieee":"K. Khudiakova, N. H. Barton, and G. Arnqvist, “Sign epistasis extends the effects of balancing selection on genetic diversity,” <i>bioRxiv</i>. .","mla":"Khudiakova, Kseniia, et al. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>.","short":"K. Khudiakova, N.H. Barton, G. Arnqvist, BioRxiv (n.d.).","chicago":"Khudiakova, Kseniia, Nicholas H Barton, and Goran Arnqvist. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>.","ista":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv, <a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>."},"OA_type":"green","OA_place":"repository","year":"2026","status":"public","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)"},"language":[{"iso":"eng"}],"related_material":{"record":[{"id":"21918","relation":"dissertation_contains","status":"public"},{"status":"public","relation":"later_version","id":"22998"}]},"corr_author":"1","title":"Sign epistasis extends the effects of balancing selection on genetic diversity","doi":"10.1101/2025.04.09.647826","date_published":"2026-04-23T00:00:00Z","oa_version":"Preprint","date_created":"2026-06-09T12:26:11Z","project":[{"name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8","grant_number":"26293"}],"date_updated":"2026-10-07T06:38:01Z"},{"ddc":["530"],"date_updated":"2026-10-07T06:57:07Z","project":[{"grant_number":"F100403","name":"Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions","_id":"7c040762-9f16-11ee-852c-dd79eeee4ab3"}],"oa_version":"Published Version","date_created":"2026-09-27T22:01:52Z","date_published":"2026-09-22T00:00:00Z","doi":"10.1103/njcx-z6np","external_id":{"arxiv":["2604.23785"]},"title":"Core-hole excitation dynamics of one-dimensional ultracold trapped fermions","corr_author":"1","das_tickbox":"1","language":[{"iso":"eng"}],"publisher":"American Physical Society","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","quality_controlled":"1","OA_place":"publisher","year":"2026","OA_type":"gold","DOAJ_listed":"1","intvolume":"         8","citation":{"apa":"Becker, A., Koutentakis, G., &#38; Schmelcher, P. (2026). Core-hole excitation dynamics of one-dimensional ultracold trapped fermions. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/njcx-z6np\">https://doi.org/10.1103/njcx-z6np</a>","ama":"Becker A, Koutentakis G, Schmelcher P. Core-hole excitation dynamics of one-dimensional ultracold trapped fermions. <i>Physical Review Research</i>. 2026;8(3). doi:<a href=\"https://doi.org/10.1103/njcx-z6np\">10.1103/njcx-z6np</a>","mla":"Becker, A., et al. “Core-Hole Excitation Dynamics of One-Dimensional Ultracold Trapped Fermions.” <i>Physical Review Research</i>, vol. 8, no. 3, 033346, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/njcx-z6np\">10.1103/njcx-z6np</a>.","ieee":"A. Becker, G. Koutentakis, and P. Schmelcher, “Core-hole excitation dynamics of one-dimensional ultracold trapped fermions,” <i>Physical Review Research</i>, vol. 8, no. 3. American Physical Society, 2026.","chicago":"Becker, A., Georgios Koutentakis, and P Schmelcher. “Core-Hole Excitation Dynamics of One-Dimensional Ultracold Trapped Fermions.” <i>Physical Review Research</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/njcx-z6np\">https://doi.org/10.1103/njcx-z6np</a>.","short":"A. Becker, G. Koutentakis, P. Schmelcher, Physical Review Research 8 (2026).","ista":"Becker A, Koutentakis G, Schmelcher P. 2026. Core-hole excitation dynamics of one-dimensional ultracold trapped fermions. Physical Review Research. 8(3), 033346."},"volume":8,"publication_identifier":{"eissn":["2643-1564"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","supplementarymaterial":"yes","_id":"23002","author":[{"last_name":"Becker","first_name":"A.","full_name":"Becker, A."},{"full_name":"Koutentakis, Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95","first_name":"Georgios","last_name":"Koutentakis"},{"full_name":"Schmelcher, P","first_name":"P","last_name":"Schmelcher"}],"PlanS_conform":"1","acknowledgement":"This work has been funded by the Cluster of Excellence “Advanced Imaging of Matter” of the Deutsche Forschungsgemeinschaft (DFG)—EXC 2056—Project No. 390715994. G.M.K. has received funding by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/F1004]. For this work, the HPC-cluster Hummel-2 at University of Hamburg was used. The cluster was funded by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—498394658.","arxiv":1,"abstract":[{"lang":"eng","text":"We investigate the nonequilibrium dynamics of core-hole excitations in a one-dimensional fermionic few-body system consisting of a spin-polarized Fermi bath coupled to a single heavy mobile impurity. The bath is initially prepared in a particle-hole configuration by emptying a selected bath single-particle orbital, while the impurity is displaced with respect to the center of the bath confinement potential. The quench dynamics are initialized by suddenly switching on the impurity-bath interaction. To resolve the resulting dynamics, we combine two complementary ab initio approaches, namely, the MultiLayer MultiConfiguration Time-Dependent Hartree method for mixtures and a multichannel Born-Oppenheimer framework. We show that the postquench response is governed by the interaction strength, impurity confinement, mass imbalance, and the location of the initially prepared hole within the Fermi sea. The density evolution and impurity center-of-mass motion reveal a competition between mixing and demixing of impurity and bath, while the von Neumann entropy demonstrates the buildup of pronounced many-body correlations. Most importantly, the occupation dynamics of the initially emptied orbital identifies deep core holes as substantially more robust against refilling than bulk or edge vacancies. Our results establish core-hole excitations as robust dynamical many-body features in trapped ultracold fermions and provide a controlled route toward probing orthogonality response, correlation buildup, and hole refilling in real time."}],"type":"journal_article","dataavailabilitystatement":"The data that support the findings of this article are not publicly available upon publication because it is not technically feasible and/or the cost of preparing, depositing, and hosting the data would be prohibitive within the terms of this research project. The data are available from the authors upon reasonable request.","issue":"3","department":[{"_id":"MiLe"}],"publication_status":"published","researchdata_availability":"upon request","has_accepted_license":"1","day":"22","month":"09","publication":"Physical Review Research","article_processing_charge":"Yes","fulldoi":"https://doi.org/10.1103/njcx-z6np","scopus_import":"1","article_number":"033346","article_type":"original","oa":1,"file_date_updated":"2026-10-07T06:55:14Z","file":[{"date_created":"2026-10-07T06:55:14Z","content_type":"application/pdf","access_level":"open_access","file_size":2520954,"date_updated":"2026-10-07T06:55:14Z","checksum":"7c886e062b11058f00c2049ba47fe3df","creator":"dernst","file_id":"23067","success":1,"file_name":"2026_PhysicalReviewResearch_BeckerA.pdf","relation":"main_file"}]},{"researchdata_availability":"yes","has_accepted_license":"1","day":"01","month":"10","dataavailabilitystatement":"The data and the source code that support the findings of this paper are openly available at: https://doi.org/10.5281/zenodo.19456426.","issue":"19","publication_status":"published","department":[{"_id":"MaSe"},{"_id":"AnHi"}],"oa":1,"file":[{"checksum":"95db327e1005564d09334763789ad7ae","creator":"dernst","date_updated":"2026-10-07T09:39:01Z","file_size":2531016,"access_level":"open_access","content_type":"application/pdf","date_created":"2026-10-07T09:39:01Z","relation":"main_file","file_name":"2026_PhysicalReviewB_Vigliotti.pdf","file_id":"23069","success":1}],"file_date_updated":"2026-10-07T09:39:01Z","article_number":"194501","article_type":"original","fulldoi":"https://doi.org/10.1103/cw3m-thsw","scopus_import":"1","publication":"Physical Review B","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":114,"publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"type":"journal_article","abstract":[{"lang":"eng","text":"Josephson junction (JJ) chains combine the coherence of superconductivity with the controllability of microwave-frequency circuits, making them a powerful platform for circuit quantum electrodynamics. In this work, we consider a long JJ chain that effectively realizes a multimode cavity with nonlinear dispersion and additional multimode interactions. Individual modes appearing due to the finite size of the chain can be experimentally probed via microwave spectroscopy, both in equilibrium and in driven far-from-equilibrium settings. We study the role of multimode interactions in degrading internal coherence—observable as excess linewidth—in both equilibrium and driven regimes. Focusing on two-into-two mode scattering as the leading relaxation process, we classify the relevant scattering processes and derive their expected temperature- and frequency-scaling under equilibrium conditions. For experimentally relevant parameters, we show that the equilibrium decay rate is dominated by nonresonant processes, however, weakly driving a particular set of modes out of equilibrium enhances resonant scattering, leading to observable signatures in the distribution function and linewidth. Finally, in the strong nonequilibrium regime, we report a crossover to a qualitatively different nonequilibrium steady state."}],"_id":"23029","author":[{"id":"539e1e1a-e604-11ee-a1df-f02b018e5c8c","full_name":"Vigliotti, Lucia","last_name":"Vigliotti","first_name":"Lucia"},{"first_name":"Andrew P","last_name":"Higginbotham","orcid":"0000-0003-2607-2363","full_name":"Higginbotham, Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-2399-5827","full_name":"Serbyn, Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym","last_name":"Serbyn"}],"acknowledgement":"We acknowledge useful discussions with Anton Bubis, Vladimir Manucharyan, Alexander Mirlin, and Thomas Scaffidi. We are grateful to Eli Levenson-Falk and Alexander Mirlin for their feedback on the manuscript. This research was supported in part by Grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP), and by the Austrian Science Fund (FWF) SFB F86.","PlanS_conform":"1","arxiv":1,"supplementarymaterial":"yes","year":"2026","OA_place":"publisher","OA_type":"hybrid","quality_controlled":"1","status":"public","citation":{"chicago":"Vigliotti, Lucia, Andrew P Higginbotham, and Maksym Serbyn. “Plasmon Decay and Nonequilibrium Steady States in Josephson Junction Chains.” <i>Physical Review B</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/cw3m-thsw\">https://doi.org/10.1103/cw3m-thsw</a>.","short":"L. Vigliotti, A.P. Higginbotham, M. Serbyn, Physical Review B 114 (2026).","mla":"Vigliotti, Lucia, et al. “Plasmon Decay and Nonequilibrium Steady States in Josephson Junction Chains.” <i>Physical Review B</i>, vol. 114, no. 19, 194501, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/cw3m-thsw\">10.1103/cw3m-thsw</a>.","ieee":"L. Vigliotti, A. P. Higginbotham, and M. Serbyn, “Plasmon decay and nonequilibrium steady states in Josephson junction chains,” <i>Physical Review B</i>, vol. 114, no. 19. American Physical Society, 2026.","ama":"Vigliotti L, Higginbotham AP, Serbyn M. Plasmon decay and nonequilibrium steady states in Josephson junction chains. <i>Physical Review B</i>. 2026;114(19). doi:<a href=\"https://doi.org/10.1103/cw3m-thsw\">10.1103/cw3m-thsw</a>","apa":"Vigliotti, L., Higginbotham, A. P., &#38; Serbyn, M. (2026). Plasmon decay and nonequilibrium steady states in Josephson junction chains. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/cw3m-thsw\">https://doi.org/10.1103/cw3m-thsw</a>","ista":"Vigliotti L, Higginbotham AP, Serbyn M. 2026. Plasmon decay and nonequilibrium steady states in Josephson junction chains. Physical Review B. 114(19), 194501."},"intvolume":"       114","external_id":{"arxiv":["2603.06371"]},"corr_author":"1","title":"Plasmon decay and nonequilibrium steady states in Josephson junction chains","date_published":"2026-10-01T00:00:00Z","doi":"10.1103/cw3m-thsw","project":[{"name":"Center for Correlated Quantum Materials and Solid State Quantum Systems:  Probing topology in circuits and quantum materials","_id":"34a7f947-11ca-11ed-8bc3-c5dc2bbaae25","grant_number":"F8609"}],"oa_version":"Published Version","date_created":"2026-10-02T08:33:31Z","ddc":["530"],"date_updated":"2026-10-07T09:42:41Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"das_tickbox":"1","publisher":"American Physical Society","language":[{"iso":"eng"}]},{"status":"public","quality_controlled":"1","OA_place":"publisher","year":"2026","OA_type":"hybrid","intvolume":"        69","citation":{"ista":"Hollom L, Lichev L, Mond A, Portier J, Wang Y. 2026. Approximate Itai–Zehavi conjecture for random graphs. Random Structures and Algorithms. 69(2), e70095.","ama":"Hollom L, Lichev L, Mond A, Portier J, Wang Y. Approximate Itai–Zehavi conjecture for random graphs. <i>Random Structures and Algorithms</i>. 2026;69(2). doi:<a href=\"https://doi.org/10.1002/rsa.70095\">10.1002/rsa.70095</a>","apa":"Hollom, L., Lichev, L., Mond, A., Portier, J., &#38; Wang, Y. (2026). Approximate Itai–Zehavi conjecture for random graphs. <i>Random Structures and Algorithms</i>. Wiley. <a href=\"https://doi.org/10.1002/rsa.70095\">https://doi.org/10.1002/rsa.70095</a>","chicago":"Hollom, Lawrence, Lyuben Lichev, Adva Mond, Julien Portier, and Yiting Wang. “Approximate Itai–Zehavi Conjecture for Random Graphs.” <i>Random Structures and Algorithms</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/rsa.70095\">https://doi.org/10.1002/rsa.70095</a>.","short":"L. Hollom, L. Lichev, A. Mond, J. Portier, Y. Wang, Random Structures and Algorithms 69 (2026).","ieee":"L. Hollom, L. Lichev, A. Mond, J. Portier, and Y. Wang, “Approximate Itai–Zehavi conjecture for random graphs,” <i>Random Structures and Algorithms</i>, vol. 69, no. 2. Wiley, 2026.","mla":"Hollom, Lawrence, et al. “Approximate Itai–Zehavi Conjecture for Random Graphs.” <i>Random Structures and Algorithms</i>, vol. 69, no. 2, e70095, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/rsa.70095\">10.1002/rsa.70095</a>."},"project":[{"_id":"bd95085b-d553-11ed-ba76-e55d3349be45","name":"Randomness and structure in combinatorics","grant_number":"101076777"}],"date_created":"2026-09-27T22:01:52Z","oa_version":"Published Version","ddc":["500"],"date_updated":"2026-10-07T07:13:30Z","title":"Approximate Itai–Zehavi conjecture for random graphs","external_id":{"arxiv":["2506.23970"]},"date_published":"2026-09-01T00:00:00Z","doi":"10.1002/rsa.70095","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"das_tickbox":"0","language":[{"iso":"eng"}],"publisher":"Wiley","issue":"2","department":[{"_id":"MaKw"},{"_id":"GradSch"}],"publication_status":"published","researchdata_availability":"no","has_accepted_license":"1","month":"09","day":"01","scopus_import":"1","fulldoi":"https://doi.org/10.1002/rsa.70095","publication":"Random Structures and Algorithms","article_processing_charge":"Yes (via OA deal)","oa":1,"file":[{"date_created":"2026-10-07T07:10:43Z","date_updated":"2026-10-07T07:10:43Z","file_size":457581,"access_level":"open_access","content_type":"application/pdf","creator":"dernst","checksum":"9a786460a47542f24576e947987e558a","success":1,"file_id":"23068","relation":"main_file","file_name":"2026_RandomStructAlgorithms_Hollom.pdf"}],"file_date_updated":"2026-10-07T07:10:43Z","article_number":"e70095","article_type":"original","volume":69,"publication_identifier":{"issn":["1042-9832"],"eissn":["1098-2418"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Hollom, Lawrence","last_name":"Hollom","first_name":"Lawrence"},{"last_name":"Lichev","first_name":"Lyuben","full_name":"Lichev, Lyuben","id":"9aa8388e-d003-11ee-8458-c4c1d7447977"},{"full_name":"Mond, Adva","last_name":"Mond","first_name":"Adva"},{"first_name":"Julien","last_name":"Portier","full_name":"Portier, Julien"},{"id":"1917d194-076e-11ed-97cd-837255f88785","full_name":"Wang, Yiting","last_name":"Wang","first_name":"Yiting"}],"_id":"23001","PlanS_conform":"1","acknowledgement":"Hollom was supported by the Internal Graduate Studentship of Trinity College, Cambridge. Mond was supported by UK Research and Innovation grant MR/W007320/2. Wang was supported by the ERC Starting Grant “RANDSTRUCT” No. 101076777. Lichev was supported by the Austrian Science Fund (FWF) [10.55776/ESP624]. For open access purposes, the authors have applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. Open Access funding provided by Technische Universitat Wien.\r\n\r\nPart of this research was done during a visit of the fourth author to IST Austria. We thank IST Austria for its hospitality. We also thank the anonymous referees for their comments and suggestions. Open Access funding provided by Technische Universitat Wien. This work was supported by the European Research Council, UK Research and Innovation, the Austrian Science Fund, and Trinity College.","arxiv":1,"supplementarymaterial":"yes","type":"journal_article","abstract":[{"text":"A famous conjecture by Itai and Zehavi states that, for every 𝑑\r\n-vertex-connected graph 𝐺\r\n and every vertex 𝑟\r\n in 𝐺\r\n, there are 𝑑\r\n spanning trees of 𝐺\r\n such that, for every vertex 𝑣\r\n in 𝐺 ∖{𝑟}\r\n, the paths between 𝑟\r\n and 𝑣\r\n in different trees are internally vertex-disjoint. We show that with high probability the Itai–Zehavi conjecture holds asymptotically for the Erdős–Rényi random graph 𝐺⁡(𝑛,𝑝)\r\n when 𝑛⁢𝑝 =𝜔⁡(log⁡𝑛)\r\n and for random regular graphs 𝐺⁡(𝑛,𝑑)\r\n when 𝑑 =𝜔⁡(log⁡𝑛)\r\n. Moreover, we essentially confirm the conjecture up to a constant factor for sparser random regular graphs. This answers a question of Draganić and Krivelevich positively. Our proof makes use of recent developments on sprinkling techniques in random regular graphs.","lang":"eng"}]},{"language":[{"iso":"eng"}],"publisher":"Wiley","das_tickbox":"1","title":"Dilute interstitial carbon stabilization of highly strained metastable HCP Nickel for enhanced electrocatalysis","external_id":{"pmid":["42745541"]},"corr_author":"1","doi":"10.1002/anie.2874510","date_published":"2026-09-15T00:00:00Z","date_created":"2026-09-27T22:01:53Z","oa_version":"None","keyword":["electrocatalysis","HCP nickel","interstitial carbon","kinetic trapping","lattice strain engineering","urea oxidation reaction"],"date_updated":"2026-10-07T08:33:58Z","pmid":1,"citation":{"ista":"Xue Q, Yu J, Dai J, Yang L, Bi X, Ren Y, Zhang J, Qi X, Wang Y, Xu Y, Arbiol J, He R, Qi X, Cabot A. 2026. Dilute interstitial carbon stabilization of highly strained metastable HCP Nickel for enhanced electrocatalysis. Angewandte Chemie International Edition., e2874510.","ama":"Xue Q, Yu J, Dai J, et al. Dilute interstitial carbon stabilization of highly strained metastable HCP Nickel for enhanced electrocatalysis. <i>Angewandte Chemie International Edition</i>. 2026. doi:<a href=\"https://doi.org/10.1002/anie.2874510\">10.1002/anie.2874510</a>","apa":"Xue, Q., Yu, J., Dai, J., Yang, L., Bi, X., Ren, Y., … Cabot, A. (2026). Dilute interstitial carbon stabilization of highly strained metastable HCP Nickel for enhanced electrocatalysis. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.2874510\">https://doi.org/10.1002/anie.2874510</a>","short":"Q. Xue, J. Yu, J. Dai, L. Yang, X. Bi, Y. Ren, J. Zhang, X. Qi, Y. Wang, Y. Xu, J. Arbiol, R. He, X. Qi, A. Cabot, Angewandte Chemie International Edition (2026).","chicago":"Xue, Qian, Jing Yu, Juguo Dai, Linlin Yang, Xiaoyu Bi, Yuchuan Ren, Jia Zhang, et al. “Dilute Interstitial Carbon Stabilization of Highly Strained Metastable HCP Nickel for Enhanced Electrocatalysis.” <i>Angewandte Chemie International Edition</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/anie.2874510\">https://doi.org/10.1002/anie.2874510</a>.","ieee":"Q. Xue <i>et al.</i>, “Dilute interstitial carbon stabilization of highly strained metastable HCP Nickel for enhanced electrocatalysis,” <i>Angewandte Chemie International Edition</i>. Wiley, 2026.","mla":"Xue, Qian, et al. “Dilute Interstitial Carbon Stabilization of Highly Strained Metastable HCP Nickel for Enhanced Electrocatalysis.” <i>Angewandte Chemie International Edition</i>, e2874510, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/anie.2874510\">10.1002/anie.2874510</a>."},"year":"2026","status":"public","quality_controlled":"1","type":"journal_article","abstract":[{"lang":"eng","text":"Lattice strain engineering can regulate the electronic structure of electrocatalysts, but stabilizing distorted metastable phases remains challenging. Here, we report an N,N-dimethylformamide-assisted strategy for synthesizing metastable hexagonal close-packed (HCP) Ni nanoparticles with local lattice-spacing deviations reaching approximately 5.2%. Structural and spectroscopic analyses support a dilute interstitial-carbon-stabilized HCP Ni framework dominated by expanded metallic Ni─Ni coordination rather than ordered Ni3C. Carbon-associated perturbations inhibit structural relaxation and retain the distorted HCP framework. Operando x-ray absorption and infrared spectroscopies indicate the formation of a NiOOH-like working surface coupled to an HCP-derived subsurface framework, accompanied by potential-dependent changes in the interfacial hydrogen-bonding environment and urea-derived species. Calculations using idealized metallic models show that HCP lattice strain induces a Ni d-band upshift, anisotropic Ni─Ni bonding, and localized charge redistribution, modifying adsorption-energy trends for the urea oxidation reaction. The optimized HCP-Ni delivers an apparent steady-state Tafel slope of 26.95 mV dec−1, over twice the electrochemically active surface area-normalized activity of the face-centered cubic-containing controls, and approximately 98% apparent urea conversion after 22 h. It sustains current for over 120 h in three-electrode testing and enables over 400 h of urea-assisted zinc–air battery cycling. This work demonstrates dilute interstitial-carbon stabilization as a route to strained metastable electrocatalysts."}],"_id":"23004","acknowledgement":"Q. X., J. Y., X. B., Y. R., J. Z. and X. Q. thank the China Scholarship Council (CSC) for the scholarship support. These experiments were performed at BL22 CLAESS (proposal 20250340148) and BL01 MIRAS(proposal 20250340424, 20250370488) beamlines at ALBA Synchrotron with the collaboration of ALBA staff. The authors acknowledge the use of instrumentation as well as the technical advice provided by JEMCA. This research was financially supported by the Science and Technology Research Program of Chongqing Municipal Education Com-mission (No. KJZD-K202401110) and the Natural Science Foundation of Chongqing (No. CSTB2023NSCQ-MSX0378). ICN2 is supported by the Severo Ochoa program from Spanish MCIN / AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Programme / Generalitat de Catalunya. ICN2 acknowledges funding from Generalitat de Catalunya2021SGR00457. The authors thank support from the project AMaDE(PID2023-149158OB-C43), funded by MCIN/ AEI/10.13039/501100011033/and by “ERDF A way of making Europe”, by the “European Union”.ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB)funded by the European Union through the European Regional Devel-opment Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member ofe-DREAM.","author":[{"full_name":"Xue, Qian","last_name":"Xue","first_name":"Qian"},{"full_name":"Yu, Jing","first_name":"Jing","last_name":"Yu"},{"full_name":"Dai, Juguo","last_name":"Dai","first_name":"Juguo"},{"full_name":"Yang, Linlin","last_name":"Yang","first_name":"Linlin"},{"last_name":"Bi","first_name":"Xiaoyu","full_name":"Bi, Xiaoyu"},{"first_name":"Yuchuan","last_name":"Ren","full_name":"Ren, Yuchuan"},{"full_name":"Zhang, Jia","first_name":"Jia","last_name":"Zhang"},{"full_name":"Qi, Xuede","first_name":"Xuede","last_name":"Qi"},{"full_name":"Wang, Yudi","last_name":"Wang","first_name":"Yudi"},{"first_name":"Ying","last_name":"Xu","full_name":"Xu, Ying"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"full_name":"He, Ren","id":"366c4efa-f61c-11f0-808b-d12a4547ac69","first_name":"Ren","last_name":"He"},{"full_name":"Qi, Xueqiang","first_name":"Xueqiang","last_name":"Qi"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"}],"supplementarymaterial":"yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"article_type":"original","article_number":"e2874510","fulldoi":"https://doi.org/10.1002/anie.2874510","scopus_import":"1","article_processing_charge":"No","publication":"Angewandte Chemie International Edition","day":"15","month":"09","researchdata_availability":"upon request","department":[{"_id":"MaIb"}],"publication_status":"epub_ahead","dataavailabilitystatement":"The data that support the findings of this study are available from thecorresponding author upon reasonable request."},{"intvolume":"       114","citation":{"ista":"Bhakuni DS, Verdel R, Desaules J-YM, Serbyn M, Ljubotina M, Dalmonte M. 2026. Anomalously fast transport in nonintegrable lattice gauge theories. Physical Review B. 114(14), L140103.","ama":"Bhakuni DS, Verdel R, Desaules J-YM, Serbyn M, Ljubotina M, Dalmonte M. Anomalously fast transport in nonintegrable lattice gauge theories. <i>Physical Review B</i>. 2026;114(14). doi:<a href=\"https://doi.org/10.1103/3371-88bl\">10.1103/3371-88bl</a>","apa":"Bhakuni, D. S., Verdel, R., Desaules, J.-Y. M., Serbyn, M., Ljubotina, M., &#38; Dalmonte, M. (2026). Anomalously fast transport in nonintegrable lattice gauge theories. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/3371-88bl\">https://doi.org/10.1103/3371-88bl</a>","short":"D.S. Bhakuni, R. Verdel, J.-Y.M. Desaules, M. Serbyn, M. Ljubotina, M. Dalmonte, Physical Review B 114 (2026).","chicago":"Bhakuni, Devendra Singh, Roberto Verdel, Jean-Yves Marc Desaules, Maksym Serbyn, Marko Ljubotina, and Marcello Dalmonte. “Anomalously Fast Transport in Nonintegrable Lattice Gauge Theories.” <i>Physical Review B</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/3371-88bl\">https://doi.org/10.1103/3371-88bl</a>.","ieee":"D. S. Bhakuni, R. Verdel, J.-Y. M. Desaules, M. Serbyn, M. Ljubotina, and M. Dalmonte, “Anomalously fast transport in nonintegrable lattice gauge theories,” <i>Physical Review B</i>, vol. 114, no. 14. American Physical Society, 2026.","mla":"Bhakuni, Devendra Singh, et al. “Anomalously Fast Transport in Nonintegrable Lattice Gauge Theories.” <i>Physical Review B</i>, vol. 114, no. 14, L140103, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/3371-88bl\">10.1103/3371-88bl</a>."},"ec_funded":1,"status":"public","quality_controlled":"1","OA_type":"green","year":"2026","OA_place":"repository","language":[{"iso":"eng"}],"publisher":"American Physical Society","das_tickbox":"1","oa_version":"Preprint","date_created":"2026-10-01T15:48:35Z","project":[{"grant_number":"850899","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"}],"date_updated":"2026-10-07T09:29:50Z","external_id":{"arxiv":["2509.08889"]},"title":"Anomalously fast transport in nonintegrable lattice gauge theories","doi":"10.1103/3371-88bl","date_published":"2026-09-09T00:00:00Z","fulldoi":"https://doi.org/10.1103/3371-88bl","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2509.08889"}],"article_processing_charge":"No","publication":"Physical Review B","oa":1,"article_type":"letter_note","article_number":"L140103","department":[{"_id":"MaSe"}],"publication_status":"published","dataavailabilitystatement":"There are no publicly available research\r\ndata or software supporting this manuscript. Requests for further information or data should be sent to the authors.","issue":"14","month":"09","day":"09","researchdata_availability":"no","arxiv":1,"author":[{"full_name":"Bhakuni, Devendra Singh","first_name":"Devendra Singh","last_name":"Bhakuni"},{"full_name":"Verdel, Roberto","last_name":"Verdel","first_name":"Roberto"},{"first_name":"Jean-Yves Marc","last_name":"Desaules","orcid":"0000-0002-3749-6375","id":"6c292945-a610-11ed-9eec-c3be1ad62a80","full_name":"Desaules, Jean-Yves Marc"},{"orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","first_name":"Maksym","last_name":"Serbyn"},{"id":"F75EE9BE-5C90-11EA-905D-16643DDC885E","full_name":"Ljubotina, Marko","orcid":"0000-0003-0038-7068","last_name":"Ljubotina","first_name":"Marko"},{"last_name":"Dalmonte","first_name":"Marcello","full_name":"Dalmonte, Marcello"}],"_id":"23027","acknowledgement":"We thank Riccardo Andreoni, Wouter\r\nBuijsman, Mario Collura, John Goold, Zala Lenarciˇ c,ˇ\r\nCristiano Muzzi, Romain Vasseur, and Marko Žnidaric for ˇ\r\ndiscussions. M.L. acknowledges support by the Deutsche\r\nForschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC-2111–\r\n390814868. M.L. and M.S. acknowledge support by the\r\nEuropean Research Council under the European Union’s\r\nHorizon 2020 research and innovation program (Grant Agreement No. 850899). J.-Y.D. acknowledges funding from the\r\nEuropean Union’s Horizon 2020 research and innovation\r\nprogramme under the Marie Skłodowska-Curie Grant Agreement No. 101034413. M.L., J.-Y.D., and M.S. acknowledge\r\nsupport by the Erwin Schrödinger International Institute\r\nfor Mathematics and Physics (ESI). M.D. was partly supported by the QUANTERA DYNAMITE PCI2022-132919,\r\nby the EU-Flagship programme Pasquans2, by the PNRR\r\nMUR Project PE0000023-NQSTI, and the PRIN programme\r\n(Project CoQuS). M.D. and R.V. were supported by the\r\nERC Consolidator Grant WaveNets. D.S.B. acknowledges\r\nthe CINECA Grant under the ISCRA-C (HP10C66VX2)\r\nprogram. The tensor network numerical simulations were performed with the ITensor library [94]. M.D. is also supported\r\nby the INFN Iniziativa specifica Quantum.","supplementarymaterial":"no","type":"journal_article","abstract":[{"lang":"eng","text":"Kinetic constraints are generally expected to slow down dynamics in many-body systems, obstructing or even\r\ncompletely suppressing transport of conserved charges. Here, we show how gauge theories can defy this wisdom\r\nby yielding constrained models with faster-than-diffusive dynamics. We first show how, upon integrating out\r\nthe gauge fields, one-dimensional U(1) lattice gauge theories are exactly mapped onto XX models with nonlocal\r\nconstraints. This class of kinetically constrained models interpolates between free theories and highly constrained\r\nlocal fermionic models. We find that energy transport is superdiffusive over a broad parameter regime. Even\r\nmore drastically, spin transport exhibits ballistic behavior, albeit with anomalous finite-volume properties as a\r\nconsequence of gauge invariance. Our findings are relevant to current efforts in quantum simulations of gauge theory dynamics and anomalous hydrodynamics in closed quantum many-body systems."}],"publication_identifier":{"issn":["2469-9950"],"eissn":["2469-9969"]},"volume":114,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"language":[{"iso":"eng"}],"das_tickbox":"1","date_updated":"2026-10-07T08:50:37Z","date_created":"2026-10-01T07:21:25Z","oa_version":"Preprint","project":[{"grant_number":"COE16","name":"Neuronal circuits in health and disease (Hippenmeyer)","_id":"9e227eae-b037-11f1-b1e2-fb7da760c1dd"}],"doi":"10.64898/2026.09.16.752114","date_published":"2026-09-18T00:00:00Z","external_id":{"biorxivid":["10.64898/2026.09.16.752114"]},"title":"A human transcriptomic deletion links cortical expansion and cancer","corr_author":"1","citation":{"ista":"Starr AL, Villalba Requena A, Rever J, Chen Y, Pauler F, Magtanong L, Maxwell CA, Hippenmeyer S, Fraser HB. A human transcriptomic deletion links cortical expansion and cancer. bioRxiv, <a href=\"https://doi.org/10.64898/2026.09.16.752114\">10.64898/2026.09.16.752114</a>.","ama":"Starr AL, Villalba Requena A, Rever J, et al. A human transcriptomic deletion links cortical expansion and cancer. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.09.16.752114\">10.64898/2026.09.16.752114</a>","apa":"Starr, A. L., Villalba Requena, A., Rever, J., Chen, Y., Pauler, F., Magtanong, L., … Fraser, H. B. (n.d.). A human transcriptomic deletion links cortical expansion and cancer. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.09.16.752114\">https://doi.org/10.64898/2026.09.16.752114</a>","short":"A.L. Starr, A. Villalba Requena, J. Rever, Y. Chen, F. Pauler, L. Magtanong, C.A. Maxwell, S. Hippenmeyer, H.B. Fraser, BioRxiv (n.d.).","chicago":"Starr, Alexander L., Ana Villalba Requena, Jenna Rever, Yuwei Chen, Florian Pauler, Leslie Magtanong, Christopher A. Maxwell, Simon Hippenmeyer, and Hunter B. Fraser. “A Human Transcriptomic Deletion Links Cortical Expansion and Cancer.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.09.16.752114\">https://doi.org/10.64898/2026.09.16.752114</a>.","mla":"Starr, Alexander L., et al. “A Human Transcriptomic Deletion Links Cortical Expansion and Cancer.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.09.16.752114\">10.64898/2026.09.16.752114</a>.","ieee":"A. L. Starr <i>et al.</i>, “A human transcriptomic deletion links cortical expansion and cancer,” <i>bioRxiv</i>. ."},"status":"public","biorxivid":1,"OA_type":"green","OA_place":"repository","year":"2026","supplementarymaterial":"yes","_id":"23011","acknowledgement":"We would like to acknowledge the MSKCC transgenic mouse core facility for generating\r\nhumanized mice, as well as Nancy Du, Xiang Chen, and other Du lab members for mouse\r\nbreeding and genotyping. This research was supported by the Scientific Service Units (SSU) of\r\nIST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support- (LSF)\r\nand Preclinical Facilities (PCF). We would also like to thank Fee Wielath and Kerstin Feistel for\r\nhelpful discussions. Some figures were made with biorender. Work in the Fraser laboratory is supported by NIH grants R01HG012285 and R35GM156526.\r\nWork in the Hippenmeyer laboratory is supported by ISTA institutional funds and FWF Cluster of\r\nExcellence COE16 (10.55776/COE16) to S.H. Work in the Maxwell laboratory is supported by\r\nthe National Sciences and Engineering Research Council of Canada (NSERC, RGPIN-2019-\r\n06215 and 2025-05766) and the Canadian Institutes of Health Research (F24-00975). J.R. is\r\nsupported by a Canada Graduate Research Scholarship-Doctoral (612468 - 2026) from\r\nNSERC. A.L.S. is supported by the FutureHouse postdoctoral fellowship program and the Kavli\r\nFoundation. ","author":[{"full_name":"Starr, Alexander L.","last_name":"Starr","first_name":"Alexander L."},{"id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","full_name":"Villalba Requena, Ana","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena","first_name":"Ana"},{"full_name":"Rever, Jenna","last_name":"Rever","first_name":"Jenna"},{"last_name":"Chen","first_name":"Yuwei","full_name":"Chen, Yuwei","id":"7f9e985d-7380-11f0-bf20-b4121a7bdcbc"},{"last_name":"Pauler","first_name":"Florian","orcid":"0000-0002-7462-0048","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian"},{"last_name":"Magtanong","first_name":"Leslie","full_name":"Magtanong, Leslie"},{"last_name":"Maxwell","first_name":"Christopher A.","full_name":"Maxwell, Christopher A."},{"last_name":"Hippenmeyer","first_name":"Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"},{"last_name":"Fraser","first_name":"Hunter B.","full_name":"Fraser, Hunter B."}],"abstract":[{"text":"Alternative splicing represents a major source of potential evolutionary novelty in protein sequence. Despite this, relatively few studies have investigated the functional impacts of human-specific alternative splicing. Here, we analyze RNA-sequencing data from nine iPSC-derived cell types and identify dozens of human transcriptomic conserved deletions (htCONDELs): evolutionary divergence in splicing that leads to the partial or full removal of conserved protein-coding sequence from the human transcriptome. We investigated one example in detail: an htCONDEL in the gene\r\nHMMR\r\n                  , which encodes a centrosomal protein that binds microtubules and regulates mitosis. We found that this htCONDEL, which produces a human-specific isoform lacking a conserved microtubule-binding domain, enables cells to flexibly divide with a broader range of mitotic spindle orientations\r\n      in vitro\r\n                  . Introducing the human\r\n                  HMMR\r\n                  isoform into mice similarly alters the orientation of cell division in the developing neocortex and increases the production of outer radial glia-like cells, the expansion of which played an essential role in increasing human brain size. Combined with previous work implicating the same\r\n                 HMMR\r\n                  isoform in carcinoma progression, our results suggest that evolution of\r\nHMMR\r\n                  splicing in humans increased plasticity in cell division, potentially leading to tradeoffs between advantageous effects on brain development and deleterious effects on cancer risk later in life.","lang":"eng"}],"type":"preprint","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","publication":"bioRxiv","fulldoi":"https://doi.org/10.64898/2026.09.16.752114","main_file_link":[{"url":"https://doi.org/10.64898/2026.09.16.752114","open_access":"1"}],"oa":1,"department":[{"_id":"SiHi"}],"publication_status":"submitted","dataavailabilitystatement":"Bulk and single cell RNA-sequencing data generated in this study have been uploaded to the\r\nGene expression omnibus (GEO) with accessions GSE346330 and GSE346338 respectively. \r\nBulk RNA-seq data used to identify htCONDELs are publicly available with the following GEO\r\naccessions: GSE146481, GSE144825, and GSE232949. Splicing data from additional species\r\nwas downloaded from https://apps.kaessmannlab.org/alternative-splicing/ and GTEx v10 sQTL\r\ndata was downloaded from https://gtexportal.org/api/v2/association/dynsqtl.\r\nCode for this study is available at: https://github.com/astarr97/Splicing. Code to perform the\r\nalignment of RNA-seq data from hybrid cells is available at: https://github.com/banwang27/multi1216 celltypes. ","month":"09","day":"18","researchdata_availability":"yes"},{"citation":{"ista":"Essner RA, Ruda K, Choh HJ, Kücükdereli H, Amsalem O, Edelhaus J, Chahyadinata G, Grødem S, Lensjø KK, Lever TE, Andermann ML. 2026. Brainstem sensing of multiple body signals during food consumption. Neuron.","ama":"Essner RA, Ruda K, Choh HJ, et al. Brainstem sensing of multiple body signals during food consumption. <i>Neuron</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.08.015\">10.1016/j.neuron.2026.08.015</a>","apa":"Essner, R. A., Ruda, K., Choh, H. J., Kücükdereli, H., Amsalem, O., Edelhaus, J., … Andermann, M. L. (2026). Brainstem sensing of multiple body signals during food consumption. <i>Neuron</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.neuron.2026.08.015\">https://doi.org/10.1016/j.neuron.2026.08.015</a>","short":"R.A. Essner, K. Ruda, H.J. Choh, H. Kücükdereli, O. Amsalem, J. Edelhaus, G. Chahyadinata, S. Grødem, K.K. Lensjø, T.E. Lever, M.L. Andermann, Neuron (2026).","chicago":"Essner, Rachel A., Kiersten Ruda, Hannah J. Choh, Hakan Kücükdereli, Oren Amsalem, Julia Edelhaus, Gracesenia Chahyadinata, et al. “Brainstem Sensing of Multiple Body Signals during Food Consumption.” <i>Neuron</i>. Cell Press, 2026. <a href=\"https://doi.org/10.1016/j.neuron.2026.08.015\">https://doi.org/10.1016/j.neuron.2026.08.015</a>.","mla":"Essner, Rachel A., et al. “Brainstem Sensing of Multiple Body Signals during Food Consumption.” <i>Neuron</i>, Cell Press, 2026, doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.08.015\">10.1016/j.neuron.2026.08.015</a>.","ieee":"R. A. Essner <i>et al.</i>, “Brainstem sensing of multiple body signals during food consumption,” <i>Neuron</i>. Cell Press, 2026."},"status":"public","quality_controlled":"1","biorxivid":1,"OA_place":"repository","year":"2026","OA_type":"green","das_tickbox":"1","publisher":"Cell Press","language":[{"iso":"eng"}],"pmid":1,"date_updated":"2026-10-07T08:40:54Z","oa_version":"Preprint","date_created":"2026-09-27T22:01:53Z","date_published":"2026-09-17T00:00:00Z","doi":"10.1016/j.neuron.2026.08.015","title":"Brainstem sensing of multiple body signals during food consumption","external_id":{"biorxivid":["10.1101/2025.04.28.651046"],"pmid":["42753729"]},"publication":"Neuron","article_processing_charge":"No","fulldoi":"https://doi.org/10.1016/j.neuron.2026.08.015","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1101/2025.04.28.651046","open_access":"1"}],"article_type":"original","oa":1,"dataavailabilitystatement":"This study did not generate any new, unique reagents.Single-neuron calcium imaging traces from all experiments have been deposited at Mendeley Data at 10.17632/wh6f8xt64y.1 and are publicly available as of the date of publication. Raw two-photon calcium imaging and fiber photometry datasets are available from the lead contact upon request.\r\nAll original code is deposited on GitHub (https://github.com/kmruda/PBN_sensing_body_signals) as well as Zenodo at 10.5281/zenodo.21926666 and is publicly available as of the date of publication.\r\nAny additional information required to reanalyze the data is available upon request from the lead contact, Mark L. Andermann (manderma@bidmc.harvard.edu).","department":[{"_id":"MaJö"}],"publication_status":"epub_ahead","researchdata_availability":"yes","day":"17","month":"09","supplementarymaterial":"yes","_id":"23003","acknowledgement":"We thank S. Zhang, K. Evans, C. Massengill, J.S. Alvarado, and members of the Andermann lab for helpful discussion and feedback. We thank J. Mathai for the use of the LabScope for fluoroscopy experiments. We thank J. Fernando, P. Prasad, D. Guarino, J. DeBolt, Z. Stolberg, and A. Pinilla for animal husbandry and other technical assistance. Authors were supported by NSF GRFP DGE1745303, NIH F31DC020631, and NIH T32DK007516 (R.A.E.); NIH F32DK135247 and NIH T32DK007516 (K.R.); the BBRF Young Investigator Grant (H.K.); the Research Council of Norway Grant 250259 (S.G. and K.K.L.); and the Pew Innovation Fund, the McKnight Foundation, the Klarman Family Foundation, the Harvard Brain Science Initiative Bipolar Disorder Seed Grant supported by Kent and Liz Dauten, the NIH (DP1AT010971, DP1DK139958, and P01HL149630), a gift from Paul Weisman, and the K. Lisa Yang Brain-Body Center (M.L.A.).","author":[{"first_name":"Rachel A.","last_name":"Essner","full_name":"Essner, Rachel A."},{"full_name":"Ruda, Kiersten","last_name":"Ruda","first_name":"Kiersten"},{"last_name":"Choh","first_name":"Hannah J.","full_name":"Choh, Hannah J."},{"first_name":"Hakan","last_name":"Kücükdereli","full_name":"Kücükdereli, Hakan","id":"5d5f6ea4-ef9e-11f0-a10a-85e12a3552af"},{"first_name":"Oren","last_name":"Amsalem","full_name":"Amsalem, Oren"},{"full_name":"Edelhaus, Julia","last_name":"Edelhaus","first_name":"Julia"},{"last_name":"Chahyadinata","first_name":"Gracesenia","full_name":"Chahyadinata, Gracesenia"},{"full_name":"Grødem, Sverre","first_name":"Sverre","last_name":"Grødem"},{"full_name":"Lensjø, Kristian K.","last_name":"Lensjø","first_name":"Kristian K."},{"full_name":"Lever, Teresa E.","last_name":"Lever","first_name":"Teresa E."},{"full_name":"Andermann, Mark L.","first_name":"Mark L.","last_name":"Andermann"}],"abstract":[{"lang":"eng","text":"The peripheral neural pathways that relay oral and post-ingestive chemo- and mechanosensory signals to the brain during food consumption are increasingly well understood. Far less is known about how these and other body signals are integrated and organized in the brainstem lateral parabrachial nucleus (LPBN), a key interoceptive sensory hub. We established methods for dense calcium imaging of 100s of neurons from mouse LPBN. Food consumption drove a seconds-long wave of activity across LPBN, with dynamics mirroring the movement of food through the upper gastrointestinal tract as observed using X-ray videofluoroscopy. By imaging the same neurons across days, we found that spatially clustered subsets of neurons encoded oral signals, stomach filling, visceral malaise, arousal, and/or body movement. Moreover, only certain subsets were modulated by cortical input. Together, these experiments establish a platform for understanding how peripheral and central interoceptive signals are integrated in the brainstem to guide behavior."}],"type":"journal_article","publication_identifier":{"eissn":["1097-4199"],"issn":["0896-6273"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"article_type":"comment","publication":"Science","article_processing_charge":"No","fulldoi":"https://doi.org/10.1126/science.ael0758","scopus_import":"1","researchdata_availability":"no","day":"17","month":"09","issue":"6817","publication_status":"published","department":[{"_id":"JaBr"}],"abstract":[{"lang":"eng","text":"Ancient viral warfare could be at the root of modern class 1 CRISPR bacterial defense systems"}],"type":"journal_article","supplementarymaterial":"no","author":[{"last_name":"Bravo","first_name":"Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","full_name":"Bravo, Jack Peter Kelly","orcid":"0000-0003-0456-0753"}],"_id":"23000","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":393,"page":"1187-1188","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"citation":{"ista":"Bravo JPK. 2026. A viral origin for RNA-guided immunity. Science. 393(6817), 1187–1188.","ieee":"J. P. K. Bravo, “A viral origin for RNA-guided immunity,” <i>Science</i>, vol. 393, no. 6817. AAAS, pp. 1187–1188, 2026.","mla":"Bravo, Jack Peter Kelly. “A Viral Origin for RNA-Guided Immunity.” <i>Science</i>, vol. 393, no. 6817, AAAS, 2026, pp. 1187–88, doi:<a href=\"https://doi.org/10.1126/science.ael0758\">10.1126/science.ael0758</a>.","chicago":"Bravo, Jack Peter Kelly. “A Viral Origin for RNA-Guided Immunity.” <i>Science</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/science.ael0758\">https://doi.org/10.1126/science.ael0758</a>.","short":"J.P.K. Bravo, Science 393 (2026) 1187–1188.","apa":"Bravo, J. P. K. (2026). A viral origin for RNA-guided immunity. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.ael0758\">https://doi.org/10.1126/science.ael0758</a>","ama":"Bravo JPK. A viral origin for RNA-guided immunity. <i>Science</i>. 2026;393(6817):1187-1188. doi:<a href=\"https://doi.org/10.1126/science.ael0758\">10.1126/science.ael0758</a>"},"intvolume":"       393","year":"2026","OA_type":"closed access","quality_controlled":"1","status":"public","das_tickbox":"0","language":[{"iso":"eng"}],"publisher":"AAAS","date_published":"2026-09-17T00:00:00Z","doi":"10.1126/science.ael0758","external_id":{"pmid":["42752153"]},"title":"A viral origin for RNA-guided immunity","corr_author":"1","date_updated":"2026-10-07T08:10:18Z","pmid":1,"date_created":"2026-09-27T22:01:52Z","oa_version":"None"}]