[{"year":"2020","ddc":["580"],"pmid":1,"article_type":"original","type":"journal_article","publisher":"Frontiers Media","date_created":"2020-01-22T15:23:57Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_published":"2020-01-22T00:00:00Z","department":[{"_id":"EvBe"}],"date_updated":"2025-06-12T07:33:02Z","external_id":{"isi":["000511376000001"],"pmid":["32038671"]},"doi":"10.3389/fpls.2019.01680","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"file":[{"date_updated":"2020-07-14T12:47:56Z","access_level":"open_access","checksum":"d1f92e60a713fbd15097ce895e5c7ccb","file_id":"7366","file_name":"2020_FrontiersPlantScience_Nibau.pdf","file_size":1951438,"creator":"dernst","relation":"main_file","content_type":"application/pdf","date_created":"2020-01-27T09:07:02Z"}],"_id":"7350","article_number":"1680","file_date_updated":"2020-07-14T12:47:56Z","oa_version":"Published Version","volume":10,"scopus_import":"1","month":"01","publication_identifier":{"issn":["1664-462X"]},"oa":1,"article_processing_charge":"No","citation":{"short":"C. Nibau, M. Gallemi, D. Dadarou, J.H. Doonan, N. Cavallari, Frontiers in Plant Science 10 (2020).","apa":"Nibau, C., Gallemi, M., Dadarou, D., Doonan, J. H., &#38; Cavallari, N. (2020). Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2. <i>Frontiers in Plant Science</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fpls.2019.01680\">https://doi.org/10.3389/fpls.2019.01680</a>","ama":"Nibau C, Gallemi M, Dadarou D, Doonan JH, Cavallari N. Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2. <i>Frontiers in Plant Science</i>. 2020;10. doi:<a href=\"https://doi.org/10.3389/fpls.2019.01680\">10.3389/fpls.2019.01680</a>","chicago":"Nibau, Candida, Marçal Gallemi, Despoina Dadarou, John H. Doonan, and Nicola Cavallari. “Thermo-Sensitive Alternative Splicing of FLOWERING LOCUS M Is Modulated by Cyclin-Dependent Kinase G2.” <i>Frontiers in Plant Science</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/fpls.2019.01680\">https://doi.org/10.3389/fpls.2019.01680</a>.","ista":"Nibau C, Gallemi M, Dadarou D, Doonan JH, Cavallari N. 2020. Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2. Frontiers in Plant Science. 10, 1680.","mla":"Nibau, Candida, et al. “Thermo-Sensitive Alternative Splicing of FLOWERING LOCUS M Is Modulated by Cyclin-Dependent Kinase G2.” <i>Frontiers in Plant Science</i>, vol. 10, 1680, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/fpls.2019.01680\">10.3389/fpls.2019.01680</a>.","ieee":"C. Nibau, M. Gallemi, D. Dadarou, J. H. Doonan, and N. Cavallari, “Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2,” <i>Frontiers in Plant Science</i>, vol. 10. Frontiers Media, 2020."},"isi":1,"author":[{"full_name":"Nibau, Candida","last_name":"Nibau","first_name":"Candida"},{"id":"460C6802-F248-11E8-B48F-1D18A9856A87","first_name":"Marçal","last_name":"Gallemi","full_name":"Gallemi, Marçal","orcid":"0000-0003-4675-6893"},{"first_name":"Despoina","last_name":"Dadarou","full_name":"Dadarou, Despoina"},{"last_name":"Doonan","first_name":"John H.","full_name":"Doonan, John H."},{"last_name":"Cavallari","first_name":"Nicola","id":"457160E6-F248-11E8-B48F-1D18A9856A87","full_name":"Cavallari, Nicola"}],"language":[{"iso":"eng"}],"quality_controlled":"1","day":"22","has_accepted_license":"1","title":"Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2","corr_author":"1","publication_status":"published","publication":"Frontiers in Plant Science","intvolume":"        10","abstract":[{"text":"The ability to sense environmental temperature and to coordinate growth and development accordingly, is critical to the reproductive success of plants. Flowering time is regulated at the level of gene expression by a complex network of factors that integrate environmental and developmental cues. One of the main players, involved in modulating flowering time in response to changes in ambient temperature is FLOWERING LOCUS M (FLM). FLM transcripts can undergo extensive alternative splicing producing multiple variants, of which FLM-β and FLM-δ are the most representative. While FLM-β codes for the flowering repressor FLM protein, translation of FLM-δ has the opposite effect on flowering. Here we show that the cyclin-dependent kinase G2 (CDKG2), together with its cognate cyclin, CYCLYN L1 (CYCL1) affects the alternative splicing of FLM, balancing the levels of FLM-β and FLM-δ across the ambient temperature range. In the absence of the CDKG2/CYCL1 complex, FLM-β expression is reduced while FLM-δ is increased in a temperature dependent manner and these changes are associated with an early flowering phenotype in the cdkg2 mutant lines. In addition, we found that transcript variants retaining the full FLM intron 1 are sequestered in the cell nucleus. Strikingly, FLM intron 1 splicing is also regulated by CDKG2/CYCL1. Our results provide evidence that temperature and CDKs regulate the alternative splicing of FLM, contributing to flowering time definition.","lang":"eng"}]},{"volume":11,"scopus_import":"1","month":"01","publication_identifier":{"eissn":["2352-7110"]},"oa":1,"arxiv":1,"author":[{"id":"40770848-F248-11E8-B48F-1D18A9856A87","first_name":"Jose M","last_name":"Lopez Alonso","full_name":"Lopez Alonso, Jose M","orcid":"0000-0002-0384-2022"},{"last_name":"Feldmann","first_name":"Daniel","full_name":"Feldmann, Daniel"},{"first_name":"Markus","last_name":"Rampp","full_name":"Rampp, Markus"},{"first_name":"Alberto","last_name":"Vela-Martín","full_name":"Vela-Martín, Alberto"},{"last_name":"Shi","id":"374A3F1A-F248-11E8-B48F-1D18A9856A87","first_name":"Liang","full_name":"Shi, Liang"},{"full_name":"Avila, Marc","first_name":"Marc","last_name":"Avila"}],"language":[{"iso":"eng"}],"citation":{"mla":"Lopez Alonso, Jose M., et al. “NsCouette – A High-Performance Code for Direct Numerical Simulations of Turbulent Taylor–Couette Flow.” <i>SoftwareX</i>, vol. 11, 100395, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.softx.2019.100395\">10.1016/j.softx.2019.100395</a>.","ieee":"J. M. Lopez Alonso, D. Feldmann, M. Rampp, A. Vela-Martín, L. Shi, and M. Avila, “nsCouette – A high-performance code for direct numerical simulations of turbulent Taylor–Couette flow,” <i>SoftwareX</i>, vol. 11. Elsevier, 2020.","short":"J.M. Lopez Alonso, D. Feldmann, M. Rampp, A. Vela-Martín, L. Shi, M. Avila, SoftwareX 11 (2020).","ama":"Lopez Alonso JM, Feldmann D, Rampp M, Vela-Martín A, Shi L, Avila M. nsCouette – A high-performance code for direct numerical simulations of turbulent Taylor–Couette flow. <i>SoftwareX</i>. 2020;11. doi:<a href=\"https://doi.org/10.1016/j.softx.2019.100395\">10.1016/j.softx.2019.100395</a>","apa":"Lopez Alonso, J. M., Feldmann, D., Rampp, M., Vela-Martín, A., Shi, L., &#38; Avila, M. (2020). nsCouette – A high-performance code for direct numerical simulations of turbulent Taylor–Couette flow. <i>SoftwareX</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.softx.2019.100395\">https://doi.org/10.1016/j.softx.2019.100395</a>","chicago":"Lopez Alonso, Jose M, Daniel Feldmann, Markus Rampp, Alberto Vela-Martín, Liang Shi, and Marc Avila. “NsCouette – A High-Performance Code for Direct Numerical Simulations of Turbulent Taylor–Couette Flow.” <i>SoftwareX</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.softx.2019.100395\">https://doi.org/10.1016/j.softx.2019.100395</a>.","ista":"Lopez Alonso JM, Feldmann D, Rampp M, Vela-Martín A, Shi L, Avila M. 2020. nsCouette – A high-performance code for direct numerical simulations of turbulent Taylor–Couette flow. SoftwareX. 11, 100395."},"isi":1,"article_processing_charge":"No","day":"17","quality_controlled":"1","publication":"SoftwareX","intvolume":"        11","abstract":[{"lang":"eng","text":"We present nsCouette, a highly scalable software tool to solve the Navier–Stokes equations for incompressible fluid flow between differentially heated and independently rotating, concentric cylinders. It is based on a pseudospectral spatial discretization and dynamic time-stepping. It is implemented in modern Fortran with a hybrid MPI-OpenMP parallelization scheme and thus designed to compute turbulent flows at high Reynolds and Rayleigh numbers. An additional GPU implementation (C-CUDA) for intermediate problem sizes and a version for pipe flow (nsPipe) are also provided."}],"has_accepted_license":"1","publication_status":"published","corr_author":"1","title":"nsCouette – A high-performance code for direct numerical simulations of turbulent Taylor–Couette flow","ddc":["000"],"year":"2020","article_type":"original","type":"journal_article","publisher":"Elsevier","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2020-01-26T23:00:35Z","status":"public","date_published":"2020-01-17T00:00:00Z","department":[{"_id":"BjHo"}],"external_id":{"isi":["000552271200011"],"arxiv":["1908.00587"]},"date_updated":"2026-04-02T14:16:50Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"doi":"10.1016/j.softx.2019.100395","file_date_updated":"2020-07-14T12:47:56Z","oa_version":"Published Version","file":[{"creator":"dernst","file_name":"2020_SoftwareX_Lopez.pdf","file_size":679707,"file_id":"7365","checksum":"2af1a1a3cc33557b345145276f221668","access_level":"open_access","date_updated":"2020-07-14T12:47:56Z","date_created":"2020-01-27T07:32:46Z","content_type":"application/pdf","relation":"main_file"}],"_id":"7364","article_number":"100395"},{"publication_identifier":{"issn":["0929-5313"],"eissn":["1573-6873"]},"volume":48,"month":"02","scopus_import":"1","page":"85-102","article_processing_charge":"Yes (via OA deal)","isi":1,"citation":{"mla":"Cubero, Ryan J., et al. “Multiscale Relevance and Informative Encoding in Neuronal Spike Trains.” <i>Journal of Computational Neuroscience</i>, vol. 48, Springer Nature, 2020, pp. 85–102, doi:<a href=\"https://doi.org/10.1007/s10827-020-00740-x\">10.1007/s10827-020-00740-x</a>.","ieee":"R. J. Cubero, M. Marsili, and Y. Roudi, “Multiscale relevance and informative encoding in neuronal spike trains,” <i>Journal of Computational Neuroscience</i>, vol. 48. Springer Nature, pp. 85–102, 2020.","apa":"Cubero, R. J., Marsili, M., &#38; Roudi, Y. (2020). Multiscale relevance and informative encoding in neuronal spike trains. <i>Journal of Computational Neuroscience</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10827-020-00740-x\">https://doi.org/10.1007/s10827-020-00740-x</a>","ama":"Cubero RJ, Marsili M, Roudi Y. Multiscale relevance and informative encoding in neuronal spike trains. <i>Journal of Computational Neuroscience</i>. 2020;48:85-102. doi:<a href=\"https://doi.org/10.1007/s10827-020-00740-x\">10.1007/s10827-020-00740-x</a>","chicago":"Cubero, Ryan J, Matteo Marsili, and Yasser Roudi. “Multiscale Relevance and Informative Encoding in Neuronal Spike Trains.” <i>Journal of Computational Neuroscience</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s10827-020-00740-x\">https://doi.org/10.1007/s10827-020-00740-x</a>.","ista":"Cubero RJ, Marsili M, Roudi Y. 2020. Multiscale relevance and informative encoding in neuronal spike trains. Journal of Computational Neuroscience. 48, 85–102.","short":"R.J. Cubero, M. Marsili, Y. Roudi, Journal of Computational Neuroscience 48 (2020) 85–102."},"author":[{"last_name":"Cubero","id":"850B2E12-9CD4-11E9-837F-E719E6697425","first_name":"Ryan J","orcid":"0000-0003-0002-1867","full_name":"Cubero, Ryan J"},{"last_name":"Marsili","first_name":"Matteo","full_name":"Marsili, Matteo"},{"first_name":"Yasser","last_name":"Roudi","full_name":"Roudi, Yasser"}],"language":[{"iso":"eng"}],"project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411"}],"acknowledgement":"This research was supported by the Kavli Foundation and the Centre of Excellence scheme of the Research Council of Norway (Centre for Neural Computation). RJC is currently receiving funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411.","oa":1,"quality_controlled":"1","day":"01","has_accepted_license":"1","publication_status":"published","corr_author":"1","title":"Multiscale relevance and informative encoding in neuronal spike trains","publication":"Journal of Computational Neuroscience","abstract":[{"text":"Neuronal responses to complex stimuli and tasks can encompass a wide range of time scales. Understanding these responses requires measures that characterize how the information on these response patterns are represented across multiple temporal resolutions. In this paper we propose a metric – which we call multiscale relevance (MSR) – to capture the dynamical variability of the activity of single neurons across different time scales. The MSR is a non-parametric, fully featureless indicator in that it uses only the time stamps of the firing activity without resorting to any a priori covariate or invoking any specific structure in the tuning curve for neural activity. When applied to neural data from the mEC and from the ADn and PoS regions of freely-behaving rodents, we found that neurons having low MSR tend to have low mutual information and low firing sparsity across the correlates that are believed to be encoded by the region of the brain where the recordings were made. In addition, neurons with high MSR contain significant information on spatial navigation and allow to decode spatial position or head direction as efficiently as those neurons whose firing activity has high mutual information with the covariate to be decoded and significantly better than the set of neurons with high local variations in their interspike intervals. Given these results, we propose that the MSR can be used as a measure to rank and select neurons for their information content without the need to appeal to any a priori covariate.","lang":"eng"}],"intvolume":"        48","ec_funded":1,"type":"journal_article","article_type":"original","publisher":"Springer Nature","year":"2020","ddc":["004","519","570"],"status":"public","date_published":"2020-02-01T00:00:00Z","keyword":["Time series analysis","Multiple time scale analysis","Spike train data","Information theory","Bayesian decoding"],"date_created":"2020-01-28T10:34:00Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2025-04-14T07:44:02Z","external_id":{"isi":["000515321800006"]},"department":[{"_id":"SaSi"}],"file":[{"date_created":"2020-01-28T09:31:09Z","content_type":"application/pdf","relation":"supplementary_material","file_size":1941355,"file_name":"10827_2020_740_MOESM1_ESM.pdf","file_id":"7380","creator":"rcubero","access_level":"open_access","date_updated":"2020-07-14T12:47:56Z","checksum":"036e9451d6cd0c190ad25791bf82393b"},{"creator":"rcubero","file_id":"7381","file_name":"Cubero2020_Article_MultiscaleRelevanceAndInformat.pdf","file_size":3257880,"checksum":"4dd8b1fd4b54486f79d82ac7b2a412b2","date_updated":"2020-07-14T12:47:56Z","access_level":"open_access","content_type":"application/pdf","date_created":"2020-01-28T09:31:09Z","relation":"main_file"}],"_id":"7369","file_date_updated":"2020-07-14T12:47:56Z","oa_version":"Published Version","doi":"10.1007/s10827-020-00740-x","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"status":"public","contributor":[{"contributor_type":"project_leader","orcid":"0000-0001-6220-2052","first_name":"Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet"}],"citation":{"ieee":"R. Grah, “Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation.” Institute of Science and Technology Austria, 2020.","mla":"Grah, Rok. <i>Matlab Scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression Regulation</i>. Institute of Science and Technology Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7383\">10.15479/AT:ISTA:7383</a>.","short":"R. Grah, (2020).","ista":"Grah R. 2020. Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:7383\">10.15479/AT:ISTA:7383</a>.","chicago":"Grah, Rok. “Matlab Scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression Regulation.” Institute of Science and Technology Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7383\">https://doi.org/10.15479/AT:ISTA:7383</a>.","apa":"Grah, R. (2020). Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7383\">https://doi.org/10.15479/AT:ISTA:7383</a>","ama":"Grah R. Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation. 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7383\">10.15479/AT:ISTA:7383</a>"},"date_published":"2020-01-28T00:00:00Z","article_processing_charge":"No","author":[{"first_name":"Rok","id":"483E70DE-F248-11E8-B48F-1D18A9856A87","last_name":"Grah","full_name":"Grah, Rok","orcid":"0000-0003-2539-3560"}],"keyword":["Matlab scripts","analysis of microfluidics","mathematical model"],"oa":1,"date_created":"2020-01-28T10:41:49Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"research_data","publisher":"Institute of Science and Technology Austria","year":"2020","month":"01","has_accepted_license":"1","file":[{"relation":"main_file","date_created":"2020-01-28T10:39:40Z","content_type":"application/zip","access_level":"open_access","date_updated":"2020-07-14T12:47:57Z","checksum":"9d292cf5207b3829225f44c044cdb3fd","file_size":73363365,"file_name":"Scripts.zip","file_id":"7384","creator":"rgrah"},{"relation":"main_file","content_type":"text/plain","date_created":"2020-01-28T10:39:30Z","date_updated":"2020-07-14T12:47:57Z","access_level":"open_access","checksum":"4076ceab32ef588cc233802bab24c1ab","file_id":"7385","file_name":"READ_ME_MAIN.txt","file_size":962,"creator":"rgrah"}],"_id":"7383","title":"Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation","corr_author":"1","file_date_updated":"2020-07-14T12:47:57Z","oa_version":"Published Version","abstract":[{"text":"Organisms cope with change by employing transcriptional regulators. However, when faced with rare environments, the evolution of transcriptional regulators and their promoters may be too slow. We ask whether the intrinsic instability of gene duplication and amplification provides a generic alternative to canonical gene regulation. By real-time monitoring of gene copy number mutations in E. coli, we show that gene duplications and amplifications enable adaptation to fluctuating environments by rapidly generating copy number, and hence expression level, polymorphism. This ‘amplification-mediated gene expression tuning’ occurs on timescales similar to canonical gene regulation and can deal with rapid environmental changes. Mathematical modeling shows that amplifications also tune gene expression in stochastic environments where transcription factor-based schemes are hard to evolve or maintain. The fleeting nature of gene amplifications gives rise to a generic population-level mechanism that relies on genetic heterogeneity to rapidly tune expression of any gene, without leaving any genomic signature.","lang":"eng"}],"doi":"10.15479/AT:ISTA:7383","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"7652"}]},"date_updated":"2025-06-12T07:34:12Z","day":"28","department":[{"_id":"CaGu"},{"_id":"GaTk"}]},{"date_updated":"2023-08-17T14:35:46Z","external_id":{"isi":["000531049800007"],"arxiv":["1902.07635"]},"department":[{"_id":"JaMa"}],"_id":"7388","oa_version":"Preprint","doi":"10.1016/j.anihpc.2020.01.003","article_type":"original","type":"journal_article","publisher":"Elsevier","year":"2020","issue":"3","status":"public","date_published":"2020-05-01T00:00:00Z","date_created":"2020-01-29T09:39:41Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","quality_controlled":"1","day":"01","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1902.07635"}],"publication_status":"published","title":"Nondivergence form quasilinear heat equations driven by space-time white noise","publication":"Annales de l'Institut Henri Poincaré C, Analyse non linéaire","abstract":[{"lang":"eng","text":"We give a Wong-Zakai type characterisation of the solutions of quasilinear heat equations driven by space-time white noise in 1 + 1 dimensions. In order to show that the renormalisation counterterms are local in the solution, a careful arrangement of a few hundred terms is required. The main tool in this computation is a general ‘integration by parts’ formula that provides a number of linear identities for the renormalisation constants."}],"intvolume":"        37","publication_identifier":{"issn":["0294-1449"]},"volume":37,"month":"05","scopus_import":"1","page":"663-682","citation":{"short":"M. Gerencser, Annales de l’Institut Henri Poincaré C, Analyse Non Linéaire 37 (2020) 663–682.","chicago":"Gerencser, Mate. “Nondivergence Form Quasilinear Heat Equations Driven by Space-Time White Noise.” <i>Annales de l’Institut Henri Poincaré C, Analyse Non Linéaire</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.anihpc.2020.01.003\">https://doi.org/10.1016/j.anihpc.2020.01.003</a>.","ista":"Gerencser M. 2020. Nondivergence form quasilinear heat equations driven by space-time white noise. Annales de l’Institut Henri Poincaré C, Analyse non linéaire. 37(3), 663–682.","ama":"Gerencser M. Nondivergence form quasilinear heat equations driven by space-time white noise. <i>Annales de l’Institut Henri Poincaré C, Analyse non linéaire</i>. 2020;37(3):663-682. doi:<a href=\"https://doi.org/10.1016/j.anihpc.2020.01.003\">10.1016/j.anihpc.2020.01.003</a>","apa":"Gerencser, M. (2020). Nondivergence form quasilinear heat equations driven by space-time white noise. <i>Annales de l’Institut Henri Poincaré C, Analyse Non Linéaire</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.anihpc.2020.01.003\">https://doi.org/10.1016/j.anihpc.2020.01.003</a>","mla":"Gerencser, Mate. “Nondivergence Form Quasilinear Heat Equations Driven by Space-Time White Noise.” <i>Annales de l’Institut Henri Poincaré C, Analyse Non Linéaire</i>, vol. 37, no. 3, Elsevier, 2020, pp. 663–82, doi:<a href=\"https://doi.org/10.1016/j.anihpc.2020.01.003\">10.1016/j.anihpc.2020.01.003</a>.","ieee":"M. Gerencser, “Nondivergence form quasilinear heat equations driven by space-time white noise,” <i>Annales de l’Institut Henri Poincaré C, Analyse non linéaire</i>, vol. 37, no. 3. Elsevier, pp. 663–682, 2020."},"isi":1,"article_processing_charge":"No","author":[{"id":"44ECEDF2-F248-11E8-B48F-1D18A9856A87","first_name":"Mate","last_name":"Gerencser","full_name":"Gerencser, Mate"}],"language":[{"iso":"eng"}],"arxiv":1,"oa":1},{"_id":"7389","oa_version":"Preprint","doi":"10.1090/tran/8113","date_updated":"2025-07-10T11:54:32Z","external_id":{"isi":["000551418100018"],"arxiv":["2002.00859"]},"department":[{"_id":"LaEr"}],"date_published":"2020-08-01T00:00:00Z","status":"public","keyword":["Wasserstein space","isometric embeddings","isometric rigidity","exotic isometry flow"],"date_created":"2020-01-29T10:20:46Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"American Mathematical Society","article_type":"original","type":"journal_article","year":"2020","issue":"8","ddc":["515"],"title":"Isometric study of Wasserstein spaces - the real line","publication_status":"published","intvolume":"       373","abstract":[{"lang":"eng","text":"Recently Kloeckner described the structure of the isometry group of the quadratic Wasserstein space W_2(R^n). It turned out that the case of the real line is exceptional in the sense that there exists an exotic isometry flow. Following this line of investigation, we compute Isom(W_p(R)), the isometry group of the Wasserstein space\r\nW_p(R) for all p \\in [1,\\infty) \\setminus {2}. We show that W_2(R) is also exceptional regarding the\r\nparameter p: W_p(R) is isometrically rigid if and only if p is not equal to 2. Regarding the underlying\r\nspace, we prove that the exceptionality of p = 2 disappears if we replace R by the compact\r\ninterval [0,1]. Surprisingly, in that case, W_p([0,1]) is isometrically rigid if and only if\r\np is not equal to 1. Moreover, W_1([0,1]) admits isometries that split mass, and Isom(W_1([0,1]))\r\ncannot be embedded into Isom(W_1(R))."}],"publication":"Transactions of the American Mathematical Society","ec_funded":1,"quality_controlled":"1","day":"01","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2002.00859"}],"isi":1,"article_processing_charge":"No","citation":{"mla":"Geher, Gyorgy Pal, et al. “Isometric Study of Wasserstein Spaces - the Real Line.” <i>Transactions of the American Mathematical Society</i>, vol. 373, no. 8, American Mathematical Society, 2020, pp. 5855–83, doi:<a href=\"https://doi.org/10.1090/tran/8113\">10.1090/tran/8113</a>.","ieee":"G. P. Geher, T. Titkos, and D. Virosztek, “Isometric study of Wasserstein spaces - the real line,” <i>Transactions of the American Mathematical Society</i>, vol. 373, no. 8. American Mathematical Society, pp. 5855–5883, 2020.","short":"G.P. Geher, T. Titkos, D. Virosztek, Transactions of the American Mathematical Society 373 (2020) 5855–5883.","ista":"Geher GP, Titkos T, Virosztek D. 2020. Isometric study of Wasserstein spaces - the real line. Transactions of the American Mathematical Society. 373(8), 5855–5883.","chicago":"Geher, Gyorgy Pal, Tamas Titkos, and Daniel Virosztek. “Isometric Study of Wasserstein Spaces - the Real Line.” <i>Transactions of the American Mathematical Society</i>. American Mathematical Society, 2020. <a href=\"https://doi.org/10.1090/tran/8113\">https://doi.org/10.1090/tran/8113</a>.","apa":"Geher, G. P., Titkos, T., &#38; Virosztek, D. (2020). Isometric study of Wasserstein spaces - the real line. <i>Transactions of the American Mathematical Society</i>. American Mathematical Society. <a href=\"https://doi.org/10.1090/tran/8113\">https://doi.org/10.1090/tran/8113</a>","ama":"Geher GP, Titkos T, Virosztek D. Isometric study of Wasserstein spaces - the real line. <i>Transactions of the American Mathematical Society</i>. 2020;373(8):5855-5883. doi:<a href=\"https://doi.org/10.1090/tran/8113\">10.1090/tran/8113</a>"},"page":"5855-5883","language":[{"iso":"eng"}],"project":[{"call_identifier":"H2020","name":"Geometric study of Wasserstein spaces and free probability","_id":"26A455A6-B435-11E9-9278-68D0E5697425","grant_number":"846294"}],"author":[{"last_name":"Geher","first_name":"Gyorgy Pal","full_name":"Geher, Gyorgy Pal"},{"full_name":"Titkos, Tamas","last_name":"Titkos","first_name":"Tamas"},{"orcid":"0000-0003-1109-5511","full_name":"Virosztek, Daniel","last_name":"Virosztek","first_name":"Daniel","id":"48DB45DA-F248-11E8-B48F-1D18A9856A87"}],"arxiv":1,"oa":1,"publication_identifier":{"eissn":["1088-6850"],"issn":["0002-9947"]},"month":"08","scopus_import":"1","volume":373},{"main_file_link":[{"url":"https://arxiv.org/abs/1808.07350","open_access":"1"}],"day":"21","quality_controlled":"1","ec_funded":1,"abstract":[{"text":"We study the Gromov waist in the sense of t-neighborhoods for measures in the Euclidean  space,  motivated  by  the  famous  theorem  of  Gromov  about  the  waist  of  radially symmetric Gaussian measures.  In particular, it turns our possible to extend Gromov’s original result  to  the  case  of  not  necessarily  radially  symmetric  Gaussian  measure.   We  also  provide examples of measures having no t-neighborhood waist property, including a rather wide class\r\nof compactly supported radially symmetric measures and their maps into the Euclidean space of dimension at least 2.\r\nWe  use  a  simpler  form  of  Gromov’s  pancake  argument  to  produce  some  estimates  of t-neighborhoods of (weighted) volume-critical submanifolds in the spirit of the waist theorems, including neighborhoods of algebraic manifolds in the complex projective space. In the appendix of this paper we provide for reader’s convenience a more detailed explanation of the Caffarelli theorem that we use to handle not necessarily radially symmetric Gaussian\r\nmeasures.","lang":"eng"}],"intvolume":"      2256","publication":"Geometric Aspects of Functional Analysis","title":"Gromov's waist of non-radial Gaussian measures and radial non-Gaussian measures","publication_status":"published","month":"06","scopus_import":"1","volume":2256,"series_title":"LNM","publication_identifier":{"eisbn":["9783030360207"],"isbn":["9783030360191"],"issn":["0075-8434"],"eissn":["1617-9692"]},"oa":1,"arxiv":1,"language":[{"iso":"eng"}],"project":[{"grant_number":"716117","_id":"256E75B8-B435-11E9-9278-68D0E5697425","name":"Optimal Transport and Stochastic Dynamics","call_identifier":"H2020"}],"author":[{"full_name":"Akopyan, Arseniy","orcid":"0000-0002-2548-617X","first_name":"Arseniy","id":"430D2C90-F248-11E8-B48F-1D18A9856A87","last_name":"Akopyan"},{"full_name":"Karasev, Roman","last_name":"Karasev","first_name":"Roman"}],"article_processing_charge":"No","citation":{"ieee":"A. Akopyan and R. Karasev, “Gromov’s waist of non-radial Gaussian measures and radial non-Gaussian measures,” in <i>Geometric Aspects of Functional Analysis</i>, vol. 2256, B. Klartag and E. Milman, Eds. Springer Nature, 2020, pp. 1–27.","mla":"Akopyan, Arseniy, and Roman Karasev. “Gromov’s Waist of Non-Radial Gaussian Measures and Radial Non-Gaussian Measures.” <i>Geometric Aspects of Functional Analysis</i>, edited by Bo’az Klartag and Emanuel Milman, vol. 2256, Springer Nature, 2020, pp. 1–27, doi:<a href=\"https://doi.org/10.1007/978-3-030-36020-7_1\">10.1007/978-3-030-36020-7_1</a>.","short":"A. Akopyan, R. Karasev, in:, B. Klartag, E. Milman (Eds.), Geometric Aspects of Functional Analysis, Springer Nature, 2020, pp. 1–27.","ama":"Akopyan A, Karasev R. Gromov’s waist of non-radial Gaussian measures and radial non-Gaussian measures. In: Klartag B, Milman E, eds. <i>Geometric Aspects of Functional Analysis</i>. Vol 2256. LNM. Springer Nature; 2020:1-27. doi:<a href=\"https://doi.org/10.1007/978-3-030-36020-7_1\">10.1007/978-3-030-36020-7_1</a>","apa":"Akopyan, A., &#38; Karasev, R. (2020). Gromov’s waist of non-radial Gaussian measures and radial non-Gaussian measures. In B. Klartag &#38; E. Milman (Eds.), <i>Geometric Aspects of Functional Analysis</i> (Vol. 2256, pp. 1–27). Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-36020-7_1\">https://doi.org/10.1007/978-3-030-36020-7_1</a>","chicago":"Akopyan, Arseniy, and Roman Karasev. “Gromov’s Waist of Non-Radial Gaussian Measures and Radial Non-Gaussian Measures.” In <i>Geometric Aspects of Functional Analysis</i>, edited by Bo’az Klartag and Emanuel Milman, 2256:1–27. LNM. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/978-3-030-36020-7_1\">https://doi.org/10.1007/978-3-030-36020-7_1</a>.","ista":"Akopyan A, Karasev R. 2020.Gromov’s waist of non-radial Gaussian measures and radial non-Gaussian measures. In: Geometric Aspects of Functional Analysis. vol. 2256, 1–27."},"isi":1,"page":"1-27","department":[{"_id":"HeEd"},{"_id":"JaMa"}],"external_id":{"arxiv":["1808.07350"],"isi":["000557689300003"]},"date_updated":"2025-07-10T11:54:33Z","doi":"10.1007/978-3-030-36020-7_1","oa_version":"Preprint","_id":"74","year":"2020","publisher":"Springer Nature","type":"book_chapter","date_created":"2018-12-11T11:44:29Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","editor":[{"first_name":"Bo'az","last_name":"Klartag","full_name":"Klartag, Bo'az"},{"last_name":"Milman","first_name":"Emanuel","full_name":"Milman, Emanuel"}],"date_published":"2020-06-21T00:00:00Z","status":"public"},{"volume":136,"scopus_import":"1","month":"01","series_title":"Current Topics in Developmental Biology","publication_identifier":{"issn":["0070-2153"],"isbn":["9780128127988"]},"page":"319-341","citation":{"short":"A.E.E. Bruce, C.-P.J. Heisenberg, in:, L. Solnica-Krezel (Ed.), Gastrulation: From Embryonic Pattern to Form, Elsevier, 2020, pp. 319–341.","ama":"Bruce AEE, Heisenberg C-PJ. Mechanisms of zebrafish epiboly: A current view. In: Solnica-Krezel L, ed. <i>Gastrulation: From Embryonic Pattern to Form</i>. Vol 136. Current Topics in Developmental Biology. Elsevier; 2020:319-341. doi:<a href=\"https://doi.org/10.1016/bs.ctdb.2019.07.001\">10.1016/bs.ctdb.2019.07.001</a>","apa":"Bruce, A. E. E., &#38; Heisenberg, C.-P. J. (2020). Mechanisms of zebrafish epiboly: A current view. In L. Solnica-Krezel (Ed.), <i>Gastrulation: From Embryonic Pattern to Form</i> (Vol. 136, pp. 319–341). Elsevier. <a href=\"https://doi.org/10.1016/bs.ctdb.2019.07.001\">https://doi.org/10.1016/bs.ctdb.2019.07.001</a>","chicago":"Bruce, Ashley E.E., and Carl-Philipp J Heisenberg. “Mechanisms of Zebrafish Epiboly: A Current View.” In <i>Gastrulation: From Embryonic Pattern to Form</i>, edited by Lilianna  Solnica-Krezel, 136:319–41. Current Topics in Developmental Biology. Elsevier, 2020. <a href=\"https://doi.org/10.1016/bs.ctdb.2019.07.001\">https://doi.org/10.1016/bs.ctdb.2019.07.001</a>.","ista":"Bruce AEE, Heisenberg C-PJ. 2020.Mechanisms of zebrafish epiboly: A current view. In: Gastrulation: From Embryonic Pattern to Form. vol. 136, 319–341.","ieee":"A. E. E. Bruce and C.-P. J. Heisenberg, “Mechanisms of zebrafish epiboly: A current view,” in <i>Gastrulation: From Embryonic Pattern to Form</i>, vol. 136, L. Solnica-Krezel, Ed. Elsevier, 2020, pp. 319–341.","mla":"Bruce, Ashley E. E., and Carl-Philipp J. Heisenberg. “Mechanisms of Zebrafish Epiboly: A Current View.” <i>Gastrulation: From Embryonic Pattern to Form</i>, edited by Lilianna  Solnica-Krezel, vol. 136, Elsevier, 2020, pp. 319–41, doi:<a href=\"https://doi.org/10.1016/bs.ctdb.2019.07.001\">10.1016/bs.ctdb.2019.07.001</a>."},"isi":1,"article_processing_charge":"No","author":[{"first_name":"Ashley E.E.","last_name":"Bruce","full_name":"Bruce, Ashley E.E."},{"last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J"}],"language":[{"iso":"eng"}],"quality_controlled":"1","day":"01","title":"Mechanisms of zebrafish epiboly: A current view","publication_status":"published","publication":"Gastrulation: From Embryonic Pattern to Form","abstract":[{"lang":"eng","text":"Epiboly is a conserved gastrulation movement describing the thinning and spreading of a sheet or multi-layer of cells. The zebrafish embryo has emerged as a vital model system to address the cellular and molecular mechanisms that drive epiboly. In the zebrafish embryo, the blastoderm, consisting of a simple squamous epithelium (the enveloping layer) and an underlying mass of deep cells, as well as a yolk nuclear syncytium (the yolk syncytial layer) undergo epiboly to internalize the yolk cell during gastrulation. The major events during zebrafish epiboly are: expansion of the enveloping layer and the internal yolk syncytial layer, reduction and removal of the yolk membrane ahead of the advancing blastoderm margin and deep cell rearrangements between the enveloping layer and yolk syncytial layer to thin the blastoderm. Here, work addressing the cellular and molecular mechanisms as well as the sources of the mechanical forces that underlie these events is reviewed. The contribution of recent findings to the current model of epiboly as well as open questions and future prospects are also discussed."}],"intvolume":"       136","year":"2020","pmid":1,"type":"book_chapter","publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-01-30T09:24:06Z","status":"public","date_published":"2020-01-01T00:00:00Z","editor":[{"last_name":"Solnica-Krezel","first_name":"Lilianna ","full_name":"Solnica-Krezel, Lilianna "}],"department":[{"_id":"CaHe"}],"date_updated":"2025-06-12T07:03:19Z","external_id":{"isi":["000611830600012"],"pmid":["31959293"]},"doi":"10.1016/bs.ctdb.2019.07.001","_id":"7410","oa_version":"None"},{"intvolume":"        15","abstract":[{"text":"Earlier, we demonstrated that transcript levels of METAL TOLERANCE PROTEIN2 (MTP2) and of HEAVY METAL ATPase2 (HMA2) increase strongly in roots of Arabidopsis upon prolonged zinc (Zn) deficiency and respond to shoot physiological Zn status, and not to the local Zn status in roots. This provided evidence for shoot-to-root communication in the acclimation of plants to Zn deficiency. Zn-deficient soils limit both the yield and quality of agricultural crops and can result in clinically relevant nutritional Zn deficiency in human populations. Implementing Zn deficiency during cultivation of the model plant Arabidopsis thaliana on agar-solidified media is difficult because trace element contaminations are present in almost all commercially available agars. Here, we demonstrate root morphological acclimations to Zn deficiency on agar-solidified medium following the effective removal of contaminants. These advancements allow reproducible phenotyping toward understanding fundamental plant responses to deficiencies of Zn and other essential trace elements.","lang":"eng"}],"publication":"Plant Signaling & Behavior","publication_status":"published","title":"Generation of effective zinc-deficient agar-solidified media allows identification of root morphology changes in response to zinc limitation","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012054","open_access":"1"}],"day":"01","quality_controlled":"1","oa":1,"language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-4566-0593","full_name":"Sinclair, Scott A","last_name":"Sinclair","first_name":"Scott A","id":"2D99FE6A-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Krämer, U.","first_name":"U.","last_name":"Krämer"}],"citation":{"ieee":"S. A. Sinclair and U. Krämer, “Generation of effective zinc-deficient agar-solidified media allows identification of root morphology changes in response to zinc limitation,” <i>Plant Signaling &#38; Behavior</i>, vol. 15, no. 1. Taylor &#38; Francis, 2020.","mla":"Sinclair, Scott A., and U. Krämer. “Generation of Effective Zinc-Deficient Agar-Solidified Media Allows Identification of Root Morphology Changes in Response to Zinc Limitation.” <i>Plant Signaling &#38; Behavior</i>, vol. 15, no. 1, 1687175, Taylor &#38; Francis, 2020, doi:<a href=\"https://doi.org/10.1080/15592324.2019.1687175\">10.1080/15592324.2019.1687175</a>.","short":"S.A. Sinclair, U. Krämer, Plant Signaling &#38; Behavior 15 (2020).","apa":"Sinclair, S. A., &#38; Krämer, U. (2020). Generation of effective zinc-deficient agar-solidified media allows identification of root morphology changes in response to zinc limitation. <i>Plant Signaling &#38; Behavior</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/15592324.2019.1687175\">https://doi.org/10.1080/15592324.2019.1687175</a>","ama":"Sinclair SA, Krämer U. Generation of effective zinc-deficient agar-solidified media allows identification of root morphology changes in response to zinc limitation. <i>Plant Signaling &#38; Behavior</i>. 2020;15(1). doi:<a href=\"https://doi.org/10.1080/15592324.2019.1687175\">10.1080/15592324.2019.1687175</a>","ista":"Sinclair SA, Krämer U. 2020. Generation of effective zinc-deficient agar-solidified media allows identification of root morphology changes in response to zinc limitation. Plant Signaling &#38; Behavior. 15(1), 1687175.","chicago":"Sinclair, Scott A, and U. Krämer. “Generation of Effective Zinc-Deficient Agar-Solidified Media Allows Identification of Root Morphology Changes in Response to Zinc Limitation.” <i>Plant Signaling &#38; Behavior</i>. Taylor &#38; Francis, 2020. <a href=\"https://doi.org/10.1080/15592324.2019.1687175\">https://doi.org/10.1080/15592324.2019.1687175</a>."},"isi":1,"article_processing_charge":"No","month":"01","scopus_import":"1","volume":15,"publication_identifier":{"issn":["1559-2324"]},"doi":"10.1080/15592324.2019.1687175","oa_version":"Submitted Version","article_number":"1687175","_id":"7416","department":[{"_id":"JiFr"}],"external_id":{"pmid":["31696764"],"isi":["000494909300001"]},"date_updated":"2023-10-17T09:01:48Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-01-30T10:12:04Z","date_published":"2020-01-01T00:00:00Z","status":"public","pmid":1,"issue":"1","year":"2020","publisher":"Taylor & Francis","article_type":"original","type":"journal_article"},{"status":"public","date_published":"2020-01-01T00:00:00Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_created":"2020-01-30T10:14:14Z","type":"journal_article","article_type":"original","publisher":"Informa UK Limited","issue":"1","pmid":1,"year":"2020","oa_version":"Submitted Version","_id":"7417","article_number":"e1687185","doi":"10.1080/15592324.2019.1687185","external_id":{"pmid":["31696770"],"isi":["000494907500001"]},"date_updated":"2023-09-06T15:23:04Z","department":[{"_id":"JiFr"}],"author":[{"full_name":"Sinclair, Scott A","orcid":"0000-0002-4566-0593","first_name":"Scott A","id":"2D99FE6A-F248-11E8-B48F-1D18A9856A87","last_name":"Sinclair"},{"full_name":"Gille, S.","first_name":"S.","last_name":"Gille"},{"last_name":"Pauly","first_name":"M.","full_name":"Pauly, M."},{"full_name":"Krämer, U.","last_name":"Krämer","first_name":"U."}],"language":[{"iso":"eng"}],"article_processing_charge":"No","citation":{"mla":"Sinclair, Scott A., et al. “Regulation of Acetylation of Plant Cell Wall Components Is Complex and Responds to External Stimuli.” <i>Plant Signaling &#38; Behavior</i>, vol. 15, no. 1, e1687185, Informa UK Limited, 2020, doi:<a href=\"https://doi.org/10.1080/15592324.2019.1687185\">10.1080/15592324.2019.1687185</a>.","ieee":"S. A. Sinclair, S. Gille, M. Pauly, and U. Krämer, “Regulation of acetylation of plant cell wall components is complex and responds to external stimuli,” <i>Plant Signaling &#38; Behavior</i>, vol. 15, no. 1. Informa UK Limited, 2020.","short":"S.A. Sinclair, S. Gille, M. Pauly, U. Krämer, Plant Signaling &#38; Behavior 15 (2020).","chicago":"Sinclair, Scott A, S. Gille, M. Pauly, and U. Krämer. “Regulation of Acetylation of Plant Cell Wall Components Is Complex and Responds to External Stimuli.” <i>Plant Signaling &#38; Behavior</i>. Informa UK Limited, 2020. <a href=\"https://doi.org/10.1080/15592324.2019.1687185\">https://doi.org/10.1080/15592324.2019.1687185</a>.","ista":"Sinclair SA, Gille S, Pauly M, Krämer U. 2020. Regulation of acetylation of plant cell wall components is complex and responds to external stimuli. Plant Signaling &#38; Behavior. 15(1), e1687185.","apa":"Sinclair, S. A., Gille, S., Pauly, M., &#38; Krämer, U. (2020). Regulation of acetylation of plant cell wall components is complex and responds to external stimuli. <i>Plant Signaling &#38; Behavior</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/15592324.2019.1687185\">https://doi.org/10.1080/15592324.2019.1687185</a>","ama":"Sinclair SA, Gille S, Pauly M, Krämer U. Regulation of acetylation of plant cell wall components is complex and responds to external stimuli. <i>Plant Signaling &#38; Behavior</i>. 2020;15(1). doi:<a href=\"https://doi.org/10.1080/15592324.2019.1687185\">10.1080/15592324.2019.1687185</a>"},"isi":1,"oa":1,"publication_identifier":{"issn":["1559-2324"]},"volume":15,"scopus_import":"1","month":"01","publication":"Plant Signaling & Behavior","intvolume":"        15","abstract":[{"text":"Previously, we reported that the allelic de-etiolated by zinc (dez) and trichome birefringence (tbr) mutants exhibit photomorphogenic development in the dark, which is enhanced by high Zn. TRICHOME BIREFRINGENCE-LIKE proteins had been implicated in transferring acetyl groups to various hemicelluloses. Pectin O-acetylation levels were lower in dark-grown dez seedlings than in the wild type. We observed Zn-enhanced photomorphogenesis in the dark also in the reduced wall acetylation 2 (rwa2-3) mutant, which exhibits lowered O-acetylation levels of cell wall macromolecules including pectins and xyloglucans, supporting a role for cell wall macromolecule O-acetylation in the photomorphogenic phenotypes of rwa2-3 and dez. Application of very short oligogalacturonides (vsOGs) restored skotomorphogenesis in dark-grown dez and rwa2-3. Here we demonstrate that in dez, O-acetylation of non-pectin cell wall components, notably of xyloglucan, is enhanced. Our results highlight the complexity of cell wall homeostasis and indicate against an influence of xyloglucan O-acetylation on light-dependent seedling development.","lang":"eng"}],"title":"Regulation of acetylation of plant cell wall components is complex and responds to external stimuli","publication_status":"published","day":"01","quality_controlled":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012154","open_access":"1"}]},{"_id":"7428","article_number":"020504","oa_version":"Preprint","doi":"10.1103/PhysRevB.101.020504","date_updated":"2025-07-10T11:54:37Z","external_id":{"arxiv":["1907.02077"],"isi":["000506843500001"]},"department":[{"_id":"MiLe"}],"status":"public","date_published":"2020-01-13T00:00:00Z","date_created":"2020-02-02T23:01:01Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","type":"journal_article","publisher":"American Physical Society","year":"2020","issue":"2","publication_status":"published","title":"Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors","publication":"Physical Review B","abstract":[{"lang":"eng","text":"In the superconducting regime of FeTe(1−x)Sex, there exist two types of vortices which are distinguished by the presence or absence of zero-energy states in their core. To understand their origin, we examine the interplay of Zeeman coupling and superconducting pairings in three-dimensional metals with band inversion. Weak Zeeman fields are found to suppress intraorbital spin-singlet pairing, known to localize the states at the ends of the vortices on the surface. On the other hand, an orbital-triplet pairing is shown to be stable against Zeeman interactions, but leads to delocalized zero-energy Majorana modes which extend through the vortex. In contrast, the finite-energy vortex modes remain localized at the vortex ends even when the pairing is of orbital-triplet form. Phenomenologically, this manifests as an observed disappearance of zero-bias peaks within the cores of topological vortices upon an increase of the applied magnetic field. The presence of magnetic impurities in FeTe(1−x)Sex, which are attracted to the vortices, would lead to such Zeeman-induced delocalization of Majorana modes in a fraction of vortices that capture a large enough number of magnetic impurities. Our results provide an explanation for the dichotomy between topological and nontopological vortices recently observed in FeTe(1−x)Sex."}],"intvolume":"       101","quality_controlled":"1","day":"13","main_file_link":[{"url":"https://arxiv.org/abs/1907.02077","open_access":"1"}],"citation":{"short":"A. Ghazaryan, P.L.S. Lopes, P. Hosur, M.J. Gilbert, P. Ghaemi, Physical Review B 101 (2020).","chicago":"Ghazaryan, Areg, P. L.S. Lopes, Pavan Hosur, Matthew J. Gilbert, and Pouyan Ghaemi. “Effect of Zeeman Coupling on the Majorana Vortex Modes in Iron-Based Topological Superconductors.” <i>Physical Review B</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/PhysRevB.101.020504\">https://doi.org/10.1103/PhysRevB.101.020504</a>.","ista":"Ghazaryan A, Lopes PLS, Hosur P, Gilbert MJ, Ghaemi P. 2020. Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors. Physical Review B. 101(2), 020504.","apa":"Ghazaryan, A., Lopes, P. L. S., Hosur, P., Gilbert, M. J., &#38; Ghaemi, P. (2020). Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.101.020504\">https://doi.org/10.1103/PhysRevB.101.020504</a>","ama":"Ghazaryan A, Lopes PLS, Hosur P, Gilbert MJ, Ghaemi P. Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors. <i>Physical Review B</i>. 2020;101(2). doi:<a href=\"https://doi.org/10.1103/PhysRevB.101.020504\">10.1103/PhysRevB.101.020504</a>","ieee":"A. Ghazaryan, P. L. S. Lopes, P. Hosur, M. J. Gilbert, and P. Ghaemi, “Effect of Zeeman coupling on the Majorana vortex modes in iron-based topological superconductors,” <i>Physical Review B</i>, vol. 101, no. 2. American Physical Society, 2020.","mla":"Ghazaryan, Areg, et al. “Effect of Zeeman Coupling on the Majorana Vortex Modes in Iron-Based Topological Superconductors.” <i>Physical Review B</i>, vol. 101, no. 2, 020504, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/PhysRevB.101.020504\">10.1103/PhysRevB.101.020504</a>."},"isi":1,"article_processing_charge":"No","author":[{"id":"4AF46FD6-F248-11E8-B48F-1D18A9856A87","first_name":"Areg","last_name":"Ghazaryan","full_name":"Ghazaryan, Areg","orcid":"0000-0001-9666-3543"},{"last_name":"Lopes","first_name":"P. L.S.","full_name":"Lopes, P. L.S."},{"last_name":"Hosur","first_name":"Pavan","full_name":"Hosur, Pavan"},{"first_name":"Matthew J.","last_name":"Gilbert","full_name":"Gilbert, Matthew J."},{"full_name":"Ghaemi, Pouyan","last_name":"Ghaemi","first_name":"Pouyan"}],"language":[{"iso":"eng"}],"arxiv":1,"oa":1,"publication_identifier":{"issn":["2469-9950"],"eissn":["2469-9969"]},"volume":101,"scopus_import":"1","month":"01"},{"date_published":"2020-01-29T00:00:00Z","status":"public","date_created":"2020-02-02T23:01:03Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"The Royal Society","type":"journal_article","article_type":"original","pmid":1,"issue":"162","year":"2020","oa_version":"Preprint","article_number":"0623","_id":"7431","doi":"10.1098/rsif.2019.0623","external_id":{"isi":["000538369800002"],"pmid":["31964273"],"arxiv":["1903.10693"]},"date_updated":"2026-04-02T14:17:25Z","department":[{"_id":"EdHa"}],"language":[{"iso":"eng"}],"author":[{"full_name":"Kolchinsky, Artemy","last_name":"Kolchinsky","first_name":"Artemy"},{"first_name":"Bernat","id":"43BE2298-F248-11E8-B48F-1D18A9856A87","last_name":"Corominas-Murtra","full_name":"Corominas-Murtra, Bernat","orcid":"0000-0001-9806-5643"}],"citation":{"mla":"Kolchinsky, Artemy, and Bernat Corominas-Murtra. “Decomposing Information into Copying versus Transformation.” <i>Journal of the Royal Society Interface</i>, vol. 17, no. 162, 0623, The Royal Society, 2020, doi:<a href=\"https://doi.org/10.1098/rsif.2019.0623\">10.1098/rsif.2019.0623</a>.","ieee":"A. Kolchinsky and B. Corominas-Murtra, “Decomposing information into copying versus transformation,” <i>Journal of the Royal Society Interface</i>, vol. 17, no. 162. The Royal Society, 2020.","ama":"Kolchinsky A, Corominas-Murtra B. Decomposing information into copying versus transformation. <i>Journal of the Royal Society Interface</i>. 2020;17(162). doi:<a href=\"https://doi.org/10.1098/rsif.2019.0623\">10.1098/rsif.2019.0623</a>","apa":"Kolchinsky, A., &#38; Corominas-Murtra, B. (2020). Decomposing information into copying versus transformation. <i>Journal of the Royal Society Interface</i>. The Royal Society. <a href=\"https://doi.org/10.1098/rsif.2019.0623\">https://doi.org/10.1098/rsif.2019.0623</a>","chicago":"Kolchinsky, Artemy, and Bernat Corominas-Murtra. “Decomposing Information into Copying versus Transformation.” <i>Journal of the Royal Society Interface</i>. The Royal Society, 2020. <a href=\"https://doi.org/10.1098/rsif.2019.0623\">https://doi.org/10.1098/rsif.2019.0623</a>.","ista":"Kolchinsky A, Corominas-Murtra B. 2020. Decomposing information into copying versus transformation. Journal of the Royal Society Interface. 17(162), 0623.","short":"A. Kolchinsky, B. Corominas-Murtra, Journal of the Royal Society Interface 17 (2020)."},"article_processing_charge":"No","isi":1,"oa":1,"acknowledgement":"AK was supported by Grant No. FQXi-RFP-1622 from the FQXi foundation, and Grant No. CHE-1648973 from the U.S.\r\nNational Science Foundation. AK would like to thank the Santa Fe Institute for supporting this research. The authors\r\nthank Jordi Fortuny, Rudolf Hanel, Joshua Garland, and Blai Vidiella for helpful discussions, as well as the anonymous\r\nreviewers for their insightful suggestions. ","arxiv":1,"publication_identifier":{"eissn":["1742-5662"]},"month":"01","scopus_import":"1","volume":17,"abstract":[{"lang":"eng","text":"In many real-world systems, information can be transmitted in two qualitatively different ways: by copying or by transformation. Copying occurs when messages are transmitted without modification, e.g. when an offspring receives an unaltered copy of a gene from its parent. Transformation occurs when messages are modified systematically during transmission, e.g. when mutational biases occur during genetic replication. Standard information-theoretic measures do not distinguish these two modes of information transfer, although they may reflect different mechanisms and have different functional consequences. Starting from a few simple axioms, we derive a decomposition of mutual information into the information transmitted by copying versus the information transmitted by transformation. We begin with a decomposition that applies when the source and destination of the channel have the same set of messages and a notion of message identity exists. We then generalize our decomposition to other kinds of channels, which can involve different source and destination sets and broader notions of similarity. In addition, we show that copy information can be interpreted as the minimal work needed by a physical copying process, which is relevant for understanding the physics of replication. We use the proposed decomposition to explore a model of amino acid substitution rates. Our results apply to any system in which the fidelity of copying, rather than simple predictability, is of critical relevance."}],"intvolume":"        17","publication":"Journal of the Royal Society Interface","publication_status":"published","title":"Decomposing information into copying versus transformation","day":"29","quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/1903.10693","open_access":"1"}]},{"publication_identifier":{"issn":["2663-337X"]},"month":"02","citation":{"mla":"Ölsböck, Katharina. <i>The Hole System of Triangulated Shapes</i>. Institute of Science and Technology Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7460\">10.15479/AT:ISTA:7460</a>.","ieee":"K. Ölsböck, “The hole system of triangulated shapes,” Institute of Science and Technology Austria, 2020.","short":"K. Ölsböck, The Hole System of Triangulated Shapes, Institute of Science and Technology Austria, 2020.","ista":"Ölsböck K. 2020. The hole system of triangulated shapes. Institute of Science and Technology Austria.","chicago":"Ölsböck, Katharina. “The Hole System of Triangulated Shapes.” Institute of Science and Technology Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7460\">https://doi.org/10.15479/AT:ISTA:7460</a>.","ama":"Ölsböck K. The hole system of triangulated shapes. 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7460\">10.15479/AT:ISTA:7460</a>","apa":"Ölsböck, K. (2020). <i>The hole system of triangulated shapes</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7460\">https://doi.org/10.15479/AT:ISTA:7460</a>"},"article_processing_charge":"No","page":"155","language":[{"iso":"eng"}],"author":[{"first_name":"Katharina","id":"4D4AA390-F248-11E8-B48F-1D18A9856A87","last_name":"Ölsböck","full_name":"Ölsböck, Katharina","orcid":"0000-0002-4672-8297"}],"oa":1,"day":"10","degree_awarded":"PhD","publication_status":"published","corr_author":"1","title":"The hole system of triangulated shapes","has_accepted_license":"1","abstract":[{"lang":"eng","text":"Many methods for the reconstruction of shapes from sets of points produce ordered simplicial complexes, which are collections of vertices, edges, triangles, and their higher-dimensional analogues, called simplices, in which every simplex gets assigned a real value measuring its size. This thesis studies ordered simplicial complexes, with a focus on their topology, which reflects the connectedness of the represented shapes and the presence of holes. We are interested both in understanding better the structure of these complexes, as well as in developing algorithms for applications.\r\n\r\nFor the Delaunay triangulation, the most popular measure for a simplex is the radius of the smallest empty circumsphere. Based on it, we revisit Alpha and Wrap complexes and experimentally determine their probabilistic properties for random data. Also, we prove the existence of tri-partitions, propose algorithms to open and close holes, and extend the concepts from Euclidean to Bregman geometries."}],"OA_place":"publisher","publisher":"Institute of Science and Technology Austria","type":"dissertation","license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","year":"2020","ddc":["514"],"date_published":"2020-02-10T00:00:00Z","status":"public","keyword":["shape reconstruction","hole manipulation","ordered complexes","Alpha complex","Wrap complex","computational topology","Bregman geometry"],"date_created":"2020-02-06T14:56:53Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"6608"}]},"date_updated":"2026-04-08T07:23:21Z","department":[{"_id":"HeEd"},{"_id":"GradSch"}],"_id":"7460","file":[{"file_id":"7461","file_size":76195184,"file_name":"thesis_ist-final_noack.pdf","creator":"koelsboe","date_updated":"2020-07-14T12:47:58Z","access_level":"open_access","checksum":"1df9f8c530b443c0e63a3f2e4fde412e","content_type":"application/pdf","date_created":"2020-02-06T14:43:54Z","relation":"main_file"},{"file_id":"7462","file_name":"latex-files.zip","file_size":122103715,"creator":"koelsboe","date_updated":"2020-07-14T12:47:58Z","description":"latex source files, figures","access_level":"closed","checksum":"7a52383c812b0be64d3826546509e5a4","content_type":"application/x-zip-compressed","date_created":"2020-02-06T14:52:45Z","relation":"source_file"}],"alternative_title":["ISTA Thesis"],"oa_version":"Published Version","file_date_updated":"2020-07-14T12:47:58Z","tmp":{"image":"/images/cc_by_nc_sa.png","short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"doi":"10.15479/AT:ISTA:7460","supervisor":[{"full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner"}]},{"year":"2020","ddc":["570"],"pmid":1,"issue":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"article_type":"original","type":"journal_article","publisher":"Public Library of Science","date_created":"2020-02-06T18:47:17Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_published":"2020-01-27T00:00:00Z","department":[{"_id":"FlSc"}],"date_updated":"2025-04-15T08:24:51Z","related_material":{"record":[{"status":"deleted","id":"9723","relation":"research_data"}]},"external_id":{"isi":["000510746400010"],"pmid":["31986188"]},"doi":"10.1371/journal.ppat.1008277","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"_id":"7464","article_number":"e1008277","file":[{"access_level":"open_access","date_updated":"2020-07-14T12:47:59Z","checksum":"a297f54d1fef0efe4789ca00f37f241e","file_name":"2020_PLOSPatho_Dick.pdf","file_size":4551246,"file_id":"7484","creator":"dernst","relation":"main_file","date_created":"2020-02-11T10:07:28Z","content_type":"application/pdf"}],"file_date_updated":"2020-07-14T12:47:59Z","oa_version":"Published Version","volume":16,"scopus_import":"1","month":"01","publication_identifier":{"issn":["1553-7374"]},"oa":1,"citation":{"ama":"Dick RA, Xu C, Morado DR, et al. Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. <i>PLOS Pathogens</i>. 2020;16(1). doi:<a href=\"https://doi.org/10.1371/journal.ppat.1008277\">10.1371/journal.ppat.1008277</a>","apa":"Dick, R. A., Xu, C., Morado, D. R., Kravchuk, V., Ricana, C. L., Lyddon, T. D., … Schur, F. K. (2020). Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. <i>PLOS Pathogens</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.ppat.1008277\">https://doi.org/10.1371/journal.ppat.1008277</a>","chicago":"Dick, Robert A., Chaoyi Xu, Dustin R. Morado, Vladyslav Kravchuk, Clifton L. Ricana, Terri D. Lyddon, Arianna M. Broad, et al. “Structures of Immature EIAV Gag Lattices Reveal a Conserved Role for IP6 in Lentivirus Assembly.” <i>PLOS Pathogens</i>. Public Library of Science, 2020. <a href=\"https://doi.org/10.1371/journal.ppat.1008277\">https://doi.org/10.1371/journal.ppat.1008277</a>.","ista":"Dick RA, Xu C, Morado DR, Kravchuk V, Ricana CL, Lyddon TD, Broad AM, Feathers JR, Johnson MC, Vogt VM, Perilla JR, Briggs JAG, Schur FK. 2020. Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. PLOS Pathogens. 16(1), e1008277.","short":"R.A. Dick, C. Xu, D.R. Morado, V. Kravchuk, C.L. Ricana, T.D. Lyddon, A.M. Broad, J.R. Feathers, M.C. Johnson, V.M. Vogt, J.R. Perilla, J.A.G. Briggs, F.K. Schur, PLOS Pathogens 16 (2020).","mla":"Dick, Robert A., et al. “Structures of Immature EIAV Gag Lattices Reveal a Conserved Role for IP6 in Lentivirus Assembly.” <i>PLOS Pathogens</i>, vol. 16, no. 1, e1008277, Public Library of Science, 2020, doi:<a href=\"https://doi.org/10.1371/journal.ppat.1008277\">10.1371/journal.ppat.1008277</a>.","ieee":"R. A. Dick <i>et al.</i>, “Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly,” <i>PLOS Pathogens</i>, vol. 16, no. 1. Public Library of Science, 2020."},"isi":1,"article_processing_charge":"No","author":[{"last_name":"Dick","first_name":"Robert A.","full_name":"Dick, Robert A."},{"full_name":"Xu, Chaoyi","first_name":"Chaoyi","last_name":"Xu"},{"full_name":"Morado, Dustin R.","first_name":"Dustin R.","last_name":"Morado"},{"full_name":"Kravchuk, Vladyslav","orcid":"0000-0001-9523-9089","first_name":"Vladyslav","id":"4D62F2A6-F248-11E8-B48F-1D18A9856A87","last_name":"Kravchuk"},{"full_name":"Ricana, Clifton L.","last_name":"Ricana","first_name":"Clifton L."},{"first_name":"Terri D.","last_name":"Lyddon","full_name":"Lyddon, Terri D."},{"full_name":"Broad, Arianna M.","first_name":"Arianna M.","last_name":"Broad"},{"first_name":"J. Ryan","last_name":"Feathers","full_name":"Feathers, J. Ryan"},{"last_name":"Johnson","first_name":"Marc C.","full_name":"Johnson, Marc C."},{"full_name":"Vogt, Volker M.","last_name":"Vogt","first_name":"Volker M."},{"full_name":"Perilla, Juan R.","first_name":"Juan R.","last_name":"Perilla"},{"last_name":"Briggs","first_name":"John A. G.","full_name":"Briggs, John A. G."},{"first_name":"Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","last_name":"Schur","full_name":"Schur, Florian KM","orcid":"0000-0003-4790-8078"}],"language":[{"iso":"eng"}],"project":[{"_id":"26736D6A-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Structural conservation and diversity in retroviral capsid","grant_number":"P31445"}],"quality_controlled":"1","day":"27","has_accepted_license":"1","publication_status":"published","corr_author":"1","title":"Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly","publication":"PLOS Pathogens","intvolume":"        16","abstract":[{"lang":"eng","text":"Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, trimeric, and hexameric protein contacts. Among retroviruses the inter- and intra-hexamer contacts differ, especially in the N-terminal sub-domain of CA (CANTD). For HIV-1 the cellular molecule inositol hexakisphosphate (IP6) interacts with and stabilizes the immature hexamer, and is required for production of infectious virus particles. We have used in vitro assembly, cryo-electron tomography and subtomogram averaging, atomistic molecular dynamics simulations and mutational analyses to study the HIV-related lentivirus equine infectious anemia virus (EIAV). In particular, we sought to understand the structural conservation of the immature lentivirus lattice and the role of IP6 in EIAV assembly. Similar to HIV-1, IP6 strongly promoted in vitro assembly of EIAV Gag proteins into virus-like particles (VLPs), which took three morphologically highly distinct forms: narrow tubes, wide tubes, and spheres. Structural characterization of these VLPs to sub-4Å resolution unexpectedly showed that all three morphologies are based on an immature lattice with preserved key structural components, highlighting the structural versatility of CA to form immature assemblies. A direct comparison between EIAV and HIV revealed that both lentiviruses maintain similar immature interfaces, which are established by both conserved and non-conserved residues. In both EIAV and HIV-1, IP6 regulates immature assembly via conserved lysine residues within the CACTD and SP. Lastly, we demonstrate that IP6 stimulates in vitro assembly of immature particles of several other retroviruses in the lentivirus genus, suggesting a conserved role for IP6 in lentiviral assembly."}]},{"oa_version":"Published Version","file_date_updated":"2020-07-14T12:47:59Z","_id":"7465","file":[{"checksum":"f7f27c6a8fea985ceb9279be2204461c","date_updated":"2020-07-14T12:47:59Z","access_level":"open_access","creator":"dernst","file_id":"7471","file_name":"2020_PlantScience_Mazur.pdf","file_size":3499069,"relation":"main_file","content_type":"application/pdf","date_created":"2020-02-10T08:59:36Z"}],"article_number":"110414","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.1016/j.plantsci.2020.110414","external_id":{"pmid":["32081263"],"isi":["000520609800009"]},"date_updated":"2026-04-07T14:18:57Z","related_material":{"record":[{"id":"11626","relation":"dissertation_contains","status":"public"}]},"department":[{"_id":"JiFr"}],"date_published":"2020-04-01T00:00:00Z","status":"public","date_created":"2020-02-09T23:00:50Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Elsevier","type":"journal_article","article_type":"original","pmid":1,"issue":"4","ddc":["580"],"year":"2020","abstract":[{"text":"The flexible development of plants is characterized by a high capacity for post-embryonic organ formation and tissue regeneration, processes, which require tightly regulated intercellular communication and coordinated tissue (re-)polarization. The phytohormone auxin, the main driver for these processes, is able to establish polarized auxin transport channels, which are characterized by the expression and polar, subcellular localization of the PIN1 auxin transport proteins. These channels are demarcating the position of future vascular strands necessary for organ formation and tissue regeneration. Major progress has been made in the last years to understand how PINs can change their polarity in different contexts and thus guide auxin flow through the plant. However, it still remains elusive how auxin mediates the establishment of auxin conducting channels and the formation of vascular tissue and which cellular processes are involved. By the means of sophisticated regeneration experiments combined with local auxin applications in Arabidopsis thaliana inflorescence stems we show that (i) PIN subcellular dynamics, (ii) PIN internalization by clathrin-mediated trafficking and (iii) an intact actin cytoskeleton required for post-endocytic trafficking are indispensable for auxin channel formation, de novo vascular formation and vascular regeneration after wounding. These observations provide novel insights into cellular mechanism of coordinated tissue polarization during auxin canalization.","lang":"eng"}],"intvolume":"       293","publication":"Plant Science","corr_author":"1","publication_status":"published","title":"Clathrin-mediated trafficking and PIN trafficking are required for auxin canalization and vascular tissue formation in Arabidopsis","has_accepted_license":"1","ec_funded":1,"day":"01","quality_controlled":"1","project":[{"_id":"261099A6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","grant_number":"742985"}],"language":[{"iso":"eng"}],"author":[{"first_name":"Ewa","last_name":"Mazur","full_name":"Mazur, Ewa"},{"first_name":"Michelle C","id":"35A03822-F248-11E8-B48F-1D18A9856A87","last_name":"Gallei","full_name":"Gallei, Michelle C","orcid":"0000-0003-1286-7368"},{"last_name":"Adamowski","id":"45F536D2-F248-11E8-B48F-1D18A9856A87","first_name":"Maciek","orcid":"0000-0001-6463-5257","full_name":"Adamowski, Maciek"},{"last_name":"Han","id":"31435098-F248-11E8-B48F-1D18A9856A87","first_name":"Huibin","full_name":"Han, Huibin"},{"last_name":"Robert","first_name":"Hélène S.","full_name":"Robert, Hélène S."},{"full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","last_name":"Friml"}],"citation":{"ieee":"E. Mazur, M. C. Gallei, M. Adamowski, H. Han, H. S. Robert, and J. Friml, “Clathrin-mediated trafficking and PIN trafficking are required for auxin canalization and vascular tissue formation in Arabidopsis,” <i>Plant Science</i>, vol. 293, no. 4. Elsevier, 2020.","mla":"Mazur, Ewa, et al. “Clathrin-Mediated Trafficking and PIN Trafficking Are Required for Auxin Canalization and Vascular Tissue Formation in Arabidopsis.” <i>Plant Science</i>, vol. 293, no. 4, 110414, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.plantsci.2020.110414\">10.1016/j.plantsci.2020.110414</a>.","ista":"Mazur E, Gallei MC, Adamowski M, Han H, Robert HS, Friml J. 2020. Clathrin-mediated trafficking and PIN trafficking are required for auxin canalization and vascular tissue formation in Arabidopsis. Plant Science. 293(4), 110414.","chicago":"Mazur, Ewa, Michelle C Gallei, Maciek Adamowski, Huibin Han, Hélène S. Robert, and Jiří Friml. “Clathrin-Mediated Trafficking and PIN Trafficking Are Required for Auxin Canalization and Vascular Tissue Formation in Arabidopsis.” <i>Plant Science</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.plantsci.2020.110414\">https://doi.org/10.1016/j.plantsci.2020.110414</a>.","ama":"Mazur E, Gallei MC, Adamowski M, Han H, Robert HS, Friml J. Clathrin-mediated trafficking and PIN trafficking are required for auxin canalization and vascular tissue formation in Arabidopsis. <i>Plant Science</i>. 2020;293(4). doi:<a href=\"https://doi.org/10.1016/j.plantsci.2020.110414\">10.1016/j.plantsci.2020.110414</a>","apa":"Mazur, E., Gallei, M. C., Adamowski, M., Han, H., Robert, H. S., &#38; Friml, J. (2020). Clathrin-mediated trafficking and PIN trafficking are required for auxin canalization and vascular tissue formation in Arabidopsis. <i>Plant Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.plantsci.2020.110414\">https://doi.org/10.1016/j.plantsci.2020.110414</a>","short":"E. Mazur, M.C. Gallei, M. Adamowski, H. Han, H.S. Robert, J. Friml, Plant Science 293 (2020)."},"isi":1,"article_processing_charge":"No","oa":1,"publication_identifier":{"eissn":["1873-2259"],"issn":["0168-9452"]},"scopus_import":"1","month":"04","volume":293},{"external_id":{"isi":["000512304800001"]},"date_updated":"2026-04-03T09:24:34Z","department":[{"_id":"DaSi"}],"file_date_updated":"2020-07-14T12:47:59Z","oa_version":"Published Version","article_number":"e51595","_id":"7466","file":[{"content_type":"application/pdf","date_created":"2020-02-10T08:53:16Z","relation":"main_file","file_id":"7470","file_name":"2020_eLife_Kierdorf.pdf","file_size":4959933,"creator":"dernst","date_updated":"2020-07-14T12:47:59Z","access_level":"open_access","checksum":"3a072be843f416c7a7d532a51dc0addb"}],"doi":"10.7554/eLife.51595","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","type":"journal_article","publisher":"eLife Sciences Publications","ddc":["570"],"year":"2020","status":"public","date_published":"2020-01-20T00:00:00Z","date_created":"2020-02-09T23:00:51Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","day":"20","quality_controlled":"1","publication":"eLife","abstract":[{"lang":"eng","text":"Unpaired ligands are secreted signals that act via a GP130-like receptor, domeless, to activate JAK/STAT signalling in Drosophila. Like many mammalian cytokines, unpaireds can be activated by infection and other stresses and can promote insulin resistance in target tissues. However, the importance of this effect in non-inflammatory physiology is unknown. Here, we identify a requirement for unpaired-JAK signalling as a metabolic regulator in healthy adult Drosophila muscle. Adult muscles show basal JAK-STAT signalling activity in the absence of any immune challenge. Plasmatocytes (Drosophila macrophages) are an important source of this tonic signal. Loss of the dome receptor on adult muscles significantly reduces lifespan and causes local and systemic metabolic pathology. These pathologies result from hyperactivation of AKT and consequent deregulation of metabolism. Thus, we identify a cytokine signal that must be received in muscle to control AKT activity and metabolic homeostasis."}],"intvolume":"         9","has_accepted_license":"1","title":"Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila","publication_status":"published","publication_identifier":{"eissn":["2050-084X"]},"volume":9,"scopus_import":"1","month":"01","author":[{"full_name":"Kierdorf, Katrin","first_name":"Katrin","last_name":"Kierdorf"},{"full_name":"Hersperger, Fabian","last_name":"Hersperger","first_name":"Fabian"},{"full_name":"Sharrock, Jessica","first_name":"Jessica","last_name":"Sharrock"},{"full_name":"Vincent, Crystal M.","first_name":"Crystal M.","last_name":"Vincent"},{"full_name":"Ustaoglu, Pinar","first_name":"Pinar","last_name":"Ustaoglu"},{"last_name":"Dou","first_name":"Jiawen","full_name":"Dou, Jiawen"},{"last_name":"György","id":"3BCEDBE0-F248-11E8-B48F-1D18A9856A87","first_name":"Attila","orcid":"0000-0002-1819-198X","full_name":"György, Attila"},{"last_name":"Groß","first_name":"Olaf","full_name":"Groß, Olaf"},{"full_name":"Siekhaus, Daria E","orcid":"0000-0001-8323-8353","first_name":"Daria E","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","last_name":"Siekhaus"},{"full_name":"Dionne, Marc S.","first_name":"Marc S.","last_name":"Dionne"}],"language":[{"iso":"eng"}],"project":[{"grant_number":"P29638","_id":"253B6E48-B435-11E9-9278-68D0E5697425","name":"The role of Drosophila TNF alpha in immune cell invasion","call_identifier":"FWF"}],"article_processing_charge":"No","citation":{"chicago":"Kierdorf, Katrin, Fabian Hersperger, Jessica Sharrock, Crystal M. Vincent, Pinar Ustaoglu, Jiawen Dou, Attila György, Olaf Groß, Daria E Siekhaus, and Marc S. Dionne. “Muscle Function and Homeostasis Require Cytokine Inhibition of AKT Activity in Drosophila.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/eLife.51595\">https://doi.org/10.7554/eLife.51595</a>.","ista":"Kierdorf K, Hersperger F, Sharrock J, Vincent CM, Ustaoglu P, Dou J, György A, Groß O, Siekhaus DE, Dionne MS. 2020. Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. eLife. 9, e51595.","apa":"Kierdorf, K., Hersperger, F., Sharrock, J., Vincent, C. M., Ustaoglu, P., Dou, J., … Dionne, M. S. (2020). Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.51595\">https://doi.org/10.7554/eLife.51595</a>","ama":"Kierdorf K, Hersperger F, Sharrock J, et al. Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/eLife.51595\">10.7554/eLife.51595</a>","short":"K. Kierdorf, F. Hersperger, J. Sharrock, C.M. Vincent, P. Ustaoglu, J. Dou, A. György, O. Groß, D.E. Siekhaus, M.S. Dionne, ELife 9 (2020).","ieee":"K. Kierdorf <i>et al.</i>, “Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020.","mla":"Kierdorf, Katrin, et al. “Muscle Function and Homeostasis Require Cytokine Inhibition of AKT Activity in Drosophila.” <i>ELife</i>, vol. 9, e51595, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/eLife.51595\">10.7554/eLife.51595</a>."},"isi":1,"oa":1},{"publisher":"IST Austria","type":"book_editor","ddc":["000"],"conference":{"name":"AHPC: Austrian High-Performance-Computing Meeting","start_date":"2020-02-19","location":"Klosterneuburg, Austria","end_date":"2020-02-21"},"year":"2020","editor":[{"last_name":"Schlögl","first_name":"Alois","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5621-8100","full_name":"Schlögl, Alois"},{"full_name":"Kiss, Janos","first_name":"Janos","id":"3D3A06F8-F248-11E8-B48F-1D18A9856A87","last_name":"Kiss"},{"id":"490F40CE-F248-11E8-B48F-1D18A9856A87","first_name":"Stefano","last_name":"Elefante","full_name":"Elefante, Stefano"}],"date_published":"2020-02-19T00:00:00Z","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-02-11T07:59:04Z","date_updated":"2023-05-16T07:48:28Z","department":[{"_id":"ScienComp"}],"oa_version":"Published Version","place":"Klosterneuburg, Austria","file_date_updated":"2020-07-14T12:47:59Z","file":[{"checksum":"49798edb9e57bbd6be18362d1d7b18a9","date_updated":"2020-07-14T12:47:59Z","access_level":"open_access","creator":"schloegl","file_id":"7504","file_name":"BOOKLET_AHPC2020.final.pdf","file_size":90899507,"relation":"main_file","content_type":"application/pdf","date_created":"2020-02-19T06:53:38Z"}],"_id":"7474","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.15479/AT:ISTA:7474","publication_identifier":{"isbn":["978-3-99078-004-6"]},"month":"02","language":[{"iso":"eng"}],"article_processing_charge":"No","citation":{"apa":"Schlögl, A., Kiss, J., &#38; Elefante, S. (Eds.). (2020). <i>Austrian High-Performance-Computing meeting (AHPC2020)</i>. Presented at the AHPC: Austrian High-Performance-Computing Meeting, Klosterneuburg, Austria: IST Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7474\">https://doi.org/10.15479/AT:ISTA:7474</a>","ama":"Schlögl A, Kiss J, Elefante S, eds. <i>Austrian High-Performance-Computing Meeting (AHPC2020)</i>. Klosterneuburg, Austria: IST Austria; 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7474\">10.15479/AT:ISTA:7474</a>","ista":"Schlögl A, Kiss J, Elefante S eds. 2020. Austrian High-Performance-Computing meeting (AHPC2020), Klosterneuburg, Austria: IST Austria, 72p.","chicago":"Schlögl, Alois, Janos Kiss, and Stefano Elefante, eds. <i>Austrian High-Performance-Computing Meeting (AHPC2020)</i>. Klosterneuburg, Austria: IST Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7474\">https://doi.org/10.15479/AT:ISTA:7474</a>.","short":"A. Schlögl, J. Kiss, S. Elefante, eds., Austrian High-Performance-Computing Meeting (AHPC2020), IST Austria, Klosterneuburg, Austria, 2020.","mla":"Schlögl, Alois, et al., editors. <i>Austrian High-Performance-Computing Meeting (AHPC2020)</i>. IST Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7474\">10.15479/AT:ISTA:7474</a>.","ieee":"A. Schlögl, J. Kiss, and S. Elefante, Eds., <i>Austrian High-Performance-Computing meeting (AHPC2020)</i>. Klosterneuburg, Austria: IST Austria, 2020."},"page":"72","oa":1,"day":"19","quality_controlled":"1","abstract":[{"text":"This booklet is a collection of abstracts presented at the AHPC conference.","lang":"eng"}],"title":"Austrian High-Performance-Computing meeting (AHPC2020)","publication_status":"published","has_accepted_license":"1"},{"publisher":"APS","article_type":"original","type":"journal_article","year":"2020","issue":"3","date_published":"2020-01-24T00:00:00Z","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-02-11T08:50:02Z","extern":"1","date_updated":"2021-01-12T08:13:48Z","external_id":{"arxiv":["1905.05505"]},"article_number":"036802","_id":"7477","oa_version":"Preprint","doi":"10.1103/physrevlett.124.036802","publication_identifier":{"issn":["0031-9007","1079-7114"]},"month":"01","volume":124,"article_processing_charge":"No","citation":{"mla":"Ménard, G. C., et al. “Conductance-Matrix Symmetries of a Three-Terminal Hybrid Device.” <i>Physical Review Letters</i>, vol. 124, no. 3, 036802, APS, 2020, doi:<a href=\"https://doi.org/10.1103/physrevlett.124.036802\">10.1103/physrevlett.124.036802</a>.","ieee":"G. C. Ménard <i>et al.</i>, “Conductance-matrix symmetries of a three-terminal hybrid device,” <i>Physical Review Letters</i>, vol. 124, no. 3. APS, 2020.","short":"G.C. Ménard, G.L.R. Anselmetti, E.A. Martinez, D. Puglia, F.K. Malinowski, J.S. Lee, S. Choi, M. Pendharkar, C.J. Palmstrøm, K. Flensberg, C.M. Marcus, L. Casparis, A.P. Higginbotham, Physical Review Letters 124 (2020).","chicago":"Ménard, G. C., G. L. R. Anselmetti, E. A. Martinez, D. Puglia, F. K. Malinowski, J. S. Lee, S. Choi, et al. “Conductance-Matrix Symmetries of a Three-Terminal Hybrid Device.” <i>Physical Review Letters</i>. APS, 2020. <a href=\"https://doi.org/10.1103/physrevlett.124.036802\">https://doi.org/10.1103/physrevlett.124.036802</a>.","ista":"Ménard GC, Anselmetti GLR, Martinez EA, Puglia D, Malinowski FK, Lee JS, Choi S, Pendharkar M, Palmstrøm CJ, Flensberg K, Marcus CM, Casparis L, Higginbotham AP. 2020. Conductance-matrix symmetries of a three-terminal hybrid device. Physical Review Letters. 124(3), 036802.","apa":"Ménard, G. C., Anselmetti, G. L. R., Martinez, E. A., Puglia, D., Malinowski, F. K., Lee, J. S., … Higginbotham, A. P. (2020). Conductance-matrix symmetries of a three-terminal hybrid device. <i>Physical Review Letters</i>. APS. <a href=\"https://doi.org/10.1103/physrevlett.124.036802\">https://doi.org/10.1103/physrevlett.124.036802</a>","ama":"Ménard GC, Anselmetti GLR, Martinez EA, et al. Conductance-matrix symmetries of a three-terminal hybrid device. <i>Physical Review Letters</i>. 2020;124(3). doi:<a href=\"https://doi.org/10.1103/physrevlett.124.036802\">10.1103/physrevlett.124.036802</a>"},"language":[{"iso":"eng"}],"author":[{"first_name":"G. C.","last_name":"Ménard","full_name":"Ménard, G. C."},{"last_name":"Anselmetti","first_name":"G. L. R.","full_name":"Anselmetti, G. L. R."},{"full_name":"Martinez, E. A.","first_name":"E. A.","last_name":"Martinez"},{"full_name":"Puglia, D.","last_name":"Puglia","first_name":"D."},{"full_name":"Malinowski, F. K.","first_name":"F. K.","last_name":"Malinowski"},{"full_name":"Lee, J. S.","last_name":"Lee","first_name":"J. S."},{"first_name":"S.","last_name":"Choi","full_name":"Choi, S."},{"full_name":"Pendharkar, M.","first_name":"M.","last_name":"Pendharkar"},{"full_name":"Palmstrøm, C. J.","last_name":"Palmstrøm","first_name":"C. J."},{"full_name":"Flensberg, K.","first_name":"K.","last_name":"Flensberg"},{"full_name":"Marcus, C. M.","last_name":"Marcus","first_name":"C. M."},{"first_name":"L.","last_name":"Casparis","full_name":"Casparis, L."},{"last_name":"Higginbotham","first_name":"Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2607-2363","full_name":"Higginbotham, Andrew P"}],"arxiv":1,"oa":1,"quality_controlled":"1","day":"24","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1905.05505"}],"publication_status":"published","title":"Conductance-matrix symmetries of a three-terminal hybrid device","intvolume":"       124","abstract":[{"lang":"eng","text":"We present conductance-matrix measurements of a three-terminal superconductor-semiconductor hybrid device consisting of two normal leads and one superconducting lead. Using a symmetry decomposition of the conductance, we find that antisymmetric components of pairs of local and nonlocal conductances qualitatively match at energies below the superconducting gap, and we compare this finding with symmetry relations based on a noninteracting scattering matrix approach. Further, the local charge character of Andreev bound states is extracted from the symmetry-decomposed conductance data and is found to be similar at both ends of the device and tunable with gate voltage. Finally, we measure the conductance matrix as a function of magnetic field and identify correlated splittings in low-energy features, demonstrating how conductance-matrix measurements can complement traditional single-probe measurements in the search for Majorana zero modes."}],"publication":"Physical Review Letters"},{"oa_version":"Preprint","article_number":"036801","_id":"7478","doi":"10.1103/physrevlett.124.036801","external_id":{"arxiv":["1905.05438"]},"date_updated":"2021-01-12T08:13:48Z","extern":"1","status":"public","date_published":"2020-01-24T00:00:00Z","date_created":"2020-02-11T08:55:40Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","type":"journal_article","publisher":"APS","issue":"3","year":"2020","publication":"Physical Review Letters","intvolume":"       124","abstract":[{"text":"Two-terminal conductance spectroscopy of superconducting devices is a common tool for probing Andreev and Majorana bound states. Here, we study theoretically a three-terminal setup, with two normal leads coupled to a grounded superconducting terminal. Using a single-electron scattering matrix, we derive the subgap conductance matrix for the normal leads and discuss its symmetries. In particular, we show that the local and the nonlocal elements of the conductance matrix have pairwise identical antisymmetric components. Moreover, we find that the nonlocal elements are directly related to the local BCS charges of the bound states close to the normal probes and we show how the BCS charge of overlapping Majorana bound states can be extracted from experiments.","lang":"eng"}],"publication_status":"published","title":"Nonlocal conductance spectroscopy of Andreev bound states: Symmetry relations and BCS charges","day":"24","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1905.05438"}],"author":[{"first_name":"Jeroen","last_name":"Danon","full_name":"Danon, Jeroen"},{"full_name":"Hellenes, Anna Birk","last_name":"Hellenes","first_name":"Anna Birk"},{"full_name":"Hansen, Esben Bork","last_name":"Hansen","first_name":"Esben Bork"},{"first_name":"Lucas","last_name":"Casparis","full_name":"Casparis, Lucas"},{"orcid":"0000-0003-2607-2363","full_name":"Higginbotham, Andrew P","last_name":"Higginbotham","first_name":"Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Flensberg, Karsten","first_name":"Karsten","last_name":"Flensberg"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","citation":{"ieee":"J. Danon, A. B. Hellenes, E. B. Hansen, L. Casparis, A. P. Higginbotham, and K. Flensberg, “Nonlocal conductance spectroscopy of Andreev bound states: Symmetry relations and BCS charges,” <i>Physical Review Letters</i>, vol. 124, no. 3. APS, 2020.","mla":"Danon, Jeroen, et al. “Nonlocal Conductance Spectroscopy of Andreev Bound States: Symmetry Relations and BCS Charges.” <i>Physical Review Letters</i>, vol. 124, no. 3, 036801, APS, 2020, doi:<a href=\"https://doi.org/10.1103/physrevlett.124.036801\">10.1103/physrevlett.124.036801</a>.","ama":"Danon J, Hellenes AB, Hansen EB, Casparis L, Higginbotham AP, Flensberg K. Nonlocal conductance spectroscopy of Andreev bound states: Symmetry relations and BCS charges. <i>Physical Review Letters</i>. 2020;124(3). doi:<a href=\"https://doi.org/10.1103/physrevlett.124.036801\">10.1103/physrevlett.124.036801</a>","apa":"Danon, J., Hellenes, A. B., Hansen, E. B., Casparis, L., Higginbotham, A. P., &#38; Flensberg, K. (2020). Nonlocal conductance spectroscopy of Andreev bound states: Symmetry relations and BCS charges. <i>Physical Review Letters</i>. APS. <a href=\"https://doi.org/10.1103/physrevlett.124.036801\">https://doi.org/10.1103/physrevlett.124.036801</a>","chicago":"Danon, Jeroen, Anna Birk Hellenes, Esben Bork Hansen, Lucas Casparis, Andrew P Higginbotham, and Karsten Flensberg. “Nonlocal Conductance Spectroscopy of Andreev Bound States: Symmetry Relations and BCS Charges.” <i>Physical Review Letters</i>. APS, 2020. <a href=\"https://doi.org/10.1103/physrevlett.124.036801\">https://doi.org/10.1103/physrevlett.124.036801</a>.","ista":"Danon J, Hellenes AB, Hansen EB, Casparis L, Higginbotham AP, Flensberg K. 2020. Nonlocal conductance spectroscopy of Andreev bound states: Symmetry relations and BCS charges. Physical Review Letters. 124(3), 036801.","short":"J. Danon, A.B. Hellenes, E.B. Hansen, L. Casparis, A.P. Higginbotham, K. Flensberg, Physical Review Letters 124 (2020)."},"oa":1,"arxiv":1,"publication_identifier":{"issn":["0031-9007","1079-7114"]},"volume":124,"month":"01"},{"quality_controlled":"1","day":"10","has_accepted_license":"1","publication_status":"published","title":"Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation","publication":"Scientific reports","abstract":[{"lang":"eng","text":"Glutaminase (GA) catalyzes the first step in mitochondrial glutaminolysis playing a key role in cancer metabolic reprogramming. Humans express two types of GA isoforms: GLS and GLS2. GLS isozymes have been consistently related to cell proliferation, but the role of GLS2 in cancer remains poorly understood. GLS2 is repressed in many tumor cells and a better understanding of its function in tumorigenesis may further the development of new therapeutic approaches. We analyzed GLS2 expression in HCC, GBM and neuroblastoma cells, as well as in monkey COS-7 cells. We studied GLS2 expression after induction of differentiation with phorbol ester (PMA) and transduction with the full-length cDNA of GLS2. In parallel, we investigated cell cycle progression and levels of p53, p21 and c-Myc proteins. Using the baculovirus system, human GLS2 protein was overexpressed, purified and analyzed for posttranslational modifications employing a proteomics LC-MS/MS platform. We have demonstrated a dual targeting of GLS2 in human cancer cells. Immunocytochemistry and subcellular fractionation gave consistent results demonstrating nuclear and mitochondrial locations, with the latter being predominant. Nuclear targeting was confirmed in cancer cells overexpressing c-Myc- and GFP-tagged GLS2 proteins. We assessed the subnuclear location finding a widespread distribution of GLS2 in the nucleoplasm without clear overlapping with specific nuclear substructures. GLS2 expression and nuclear accrual notably increased by treatment of SH-SY5Y cells with PMA and it correlated with cell cycle arrest at G2/M, upregulation of tumor suppressor p53 and p21 protein. A similar response was obtained by overexpression of GLS2 in T98G glioma cells, including downregulation of oncogene c-Myc. Furthermore, human GLS2 was identified as being hypusinated by MS analysis, a posttranslational modification which may be relevant for its nuclear targeting and/or function. Our studies provide evidence for a tumor suppressor role of GLS2 in certain types of cancer. The data imply that GLS2 can be regarded as a highly mobile and multilocalizing protein translocated to both mitochondria and nuclei. Upregulation of GLS2 in cancer cells induced an antiproliferative response with cell cycle arrest at the G2/M phase."}],"intvolume":"        10","volume":10,"scopus_import":"1","month":"02","publication_identifier":{"eissn":["2045-2322"]},"oa":1,"citation":{"mla":"López De La Oliva, Amada R., et al. “Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation.” <i>Scientific Reports</i>, vol. 10, no. 1, 2259, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41598-020-58264-4\">10.1038/s41598-020-58264-4</a>.","ieee":"A. R. López De La Oliva <i>et al.</i>, “Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation,” <i>Scientific reports</i>, vol. 10, no. 1. Springer Nature, 2020.","short":"A.R. López De La Oliva, J.A. Campos-Sandoval, M.C. Gómez-García, C. Cardona, M. Martín-Rufián, F.J. Sialana, L. Castilla, N. Bae, C. Lobo, A. Peñalver, M. García-Frutos, D. Carro, V. Enrique, J.C. Paz, R.G. Mirmira, A. Gutiérrez, F.J. Alonso, J.A. Segura, J.M. Matés, G. Lubec, J. Márquez, Scientific Reports 10 (2020).","ama":"López De La Oliva AR, Campos-Sandoval JA, Gómez-García MC, et al. Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation. <i>Scientific reports</i>. 2020;10(1). doi:<a href=\"https://doi.org/10.1038/s41598-020-58264-4\">10.1038/s41598-020-58264-4</a>","apa":"López De La Oliva, A. R., Campos-Sandoval, J. A., Gómez-García, M. C., Cardona, C., Martín-Rufián, M., Sialana, F. J., … Márquez, J. (2020). Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-020-58264-4\">https://doi.org/10.1038/s41598-020-58264-4</a>","chicago":"López De La Oliva, Amada R., José A. Campos-Sandoval, María C. Gómez-García, Carolina Cardona, Mercedes Martín-Rufián, Fernando J. Sialana, Laura Castilla, et al. “Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation.” <i>Scientific Reports</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41598-020-58264-4\">https://doi.org/10.1038/s41598-020-58264-4</a>.","ista":"López De La Oliva AR, Campos-Sandoval JA, Gómez-García MC, Cardona C, Martín-Rufián M, Sialana FJ, Castilla L, Bae N, Lobo C, Peñalver A, García-Frutos M, Carro D, Enrique V, Paz JC, Mirmira RG, Gutiérrez A, Alonso FJ, Segura JA, Matés JM, Lubec G, Márquez J. 2020. Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation. Scientific reports. 10(1), 2259."},"isi":1,"article_processing_charge":"No","author":[{"last_name":"López De La Oliva","first_name":"Amada R.","full_name":"López De La Oliva, Amada R."},{"first_name":"José A.","last_name":"Campos-Sandoval","full_name":"Campos-Sandoval, José A."},{"first_name":"María C.","last_name":"Gómez-García","full_name":"Gómez-García, María C."},{"full_name":"Cardona, Carolina","last_name":"Cardona","first_name":"Carolina"},{"full_name":"Martín-Rufián, Mercedes","last_name":"Martín-Rufián","first_name":"Mercedes"},{"first_name":"Fernando J.","last_name":"Sialana","full_name":"Sialana, Fernando J."},{"full_name":"Castilla, Laura","last_name":"Castilla","first_name":"Laura"},{"first_name":"Narkhyun","id":"3A5F7CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Bae","full_name":"Bae, Narkhyun"},{"last_name":"Lobo","first_name":"Carolina","full_name":"Lobo, Carolina"},{"first_name":"Ana","last_name":"Peñalver","full_name":"Peñalver, Ana"},{"full_name":"García-Frutos, Marina","last_name":"García-Frutos","first_name":"Marina"},{"last_name":"Carro","first_name":"David","full_name":"Carro, David"},{"full_name":"Enrique, Victoria","last_name":"Enrique","first_name":"Victoria"},{"last_name":"Paz","first_name":"José C.","full_name":"Paz, José C."},{"full_name":"Mirmira, Raghavendra G.","first_name":"Raghavendra G.","last_name":"Mirmira"},{"full_name":"Gutiérrez, Antonia","last_name":"Gutiérrez","first_name":"Antonia"},{"full_name":"Alonso, Francisco J.","first_name":"Francisco J.","last_name":"Alonso"},{"first_name":"Juan A.","last_name":"Segura","full_name":"Segura, Juan A."},{"full_name":"Matés, José M.","last_name":"Matés","first_name":"José M."},{"full_name":"Lubec, Gert","last_name":"Lubec","first_name":"Gert"},{"full_name":"Márquez, Javier","last_name":"Márquez","first_name":"Javier"}],"language":[{"iso":"eng"}],"department":[{"_id":"CaBe"}],"related_material":{"link":[{"url":"https://doi.org/10.1038/s41598-020-80651-0","relation":"erratum"}]},"date_updated":"2026-04-02T11:51:06Z","external_id":{"isi":["000560694800012"],"pmid":["32042057"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"doi":"10.1038/s41598-020-58264-4","file":[{"file_name":"2020_ScientificReport_Lopez.pdf","file_size":4703751,"file_id":"7495","creator":"dernst","access_level":"open_access","date_updated":"2020-07-14T12:47:59Z","checksum":"c780bd87476a9c9e12668ff66de3dc96","date_created":"2020-02-18T07:43:21Z","content_type":"application/pdf","relation":"main_file"}],"_id":"7487","article_number":"2259","file_date_updated":"2020-07-14T12:47:59Z","oa_version":"Published Version","year":"2020","ddc":["570"],"pmid":1,"issue":"1","type":"journal_article","article_type":"original","publisher":"Springer Nature","date_created":"2020-02-16T23:00:49Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","status":"public","date_published":"2020-02-10T00:00:00Z"}]