[{"doi":"10.1371/journal.pcbi.1013890","DOAJ_listed":"1","publication_status":"published","publication":"PLoS Computational Biology","abstract":[{"lang":"eng","text":"Quantifying cell morphology is central to understanding cellular regulation, fate, and heterogeneity, yet conventional image-based analyses often struggle with diverse or irregular shapes. We present a computational framework that uses topological data analysis to characterise and compare single-cell morphologies from fluorescence microscopy. Each cell is represented by its contour together with the position of its nucleus, from which we construct a filtration based on a radial distance function and derive a persistence diagram encoding the shape’s topological evolution. The similarity between two cells is quantified using the 2-Wasserstein distance between their diagrams, yielding a shape distance we call the PH distance. We apply this method to two representative experimental systems—primary human mesenchymal stem cells (hMSCs) and HeLa cells—and show that PH distances enable the detection of outliers in those systems, the identification of sub-populations, and the quantification of shape heterogeneity. We benchmark PH against three established contour-based distances (aspect ratio, Fourier descriptors, and elastic shape analysis) and show that PH offers better separation between cell types and greater robustness when clustering heterogeneous populations. Together, these results demonstrate that persistent-homology-based signatures provide a principled and sensitive approach for analysing cell morphology in settings where traditional geometric or image-based descriptors are insufficient."}],"file":[{"access_level":"open_access","relation":"main_file","content_type":"application/pdf","date_created":"2026-02-10T07:13:06Z","file_size":8908746,"date_updated":"2026-02-10T07:13:06Z","file_id":"21204","creator":"dernst","file_name":"2026_PloSCompBio_Bleile.pdf","success":1,"checksum":"3899d929ee9be0453c95524e49992d72"}],"publication_identifier":{"issn":["1553-7358"]},"pmid":1,"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Public Library of Science","article_type":"original","date_created":"2026-01-30T10:36:32Z","OA_place":"publisher","file_date_updated":"2026-02-10T07:13:06Z","day":"28","intvolume":"        22","oa":1,"type":"journal_article","article_processing_charge":"Yes","citation":{"mla":"Bokor Bleile, Yossi, et al. “Persistence Diagrams as Morphological Signatures of Cells: A Method to Measure and Compare Cells within a Population.” <i>PLoS Computational Biology</i>, vol. 22, e1013890, Public Library of Science, 2026, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1013890\">10.1371/journal.pcbi.1013890</a>.","apa":"Bokor Bleile, Y., Yadav, P., Koehl, P., &#38; Rehfeldt, F. (2026). Persistence diagrams as morphological signatures of cells: A method to measure and compare cells within a population. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1013890\">https://doi.org/10.1371/journal.pcbi.1013890</a>","ista":"Bokor Bleile Y, Yadav P, Koehl P, Rehfeldt F. 2026. Persistence diagrams as morphological signatures of cells: A method to measure and compare cells within a population. PLoS Computational Biology. 22, e1013890.","ieee":"Y. Bokor Bleile, P. Yadav, P. Koehl, and F. Rehfeldt, “Persistence diagrams as morphological signatures of cells: A method to measure and compare cells within a population,” <i>PLoS Computational Biology</i>, vol. 22. Public Library of Science, 2026.","ama":"Bokor Bleile Y, Yadav P, Koehl P, Rehfeldt F. Persistence diagrams as morphological signatures of cells: A method to measure and compare cells within a population. <i>PLoS Computational Biology</i>. 2026;22. doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1013890\">10.1371/journal.pcbi.1013890</a>","short":"Y. Bokor Bleile, P. Yadav, P. Koehl, F. Rehfeldt, PLoS Computational Biology 22 (2026).","chicago":"Bokor Bleile, Yossi, Pooja Yadav, Patrice Koehl, and Florian Rehfeldt. “Persistence Diagrams as Morphological Signatures of Cells: A Method to Measure and Compare Cells within a Population.” <i>PLoS Computational Biology</i>. Public Library of Science, 2026. <a href=\"https://doi.org/10.1371/journal.pcbi.1013890\">https://doi.org/10.1371/journal.pcbi.1013890</a>."},"acknowledgement":"We thank Stephan Huckemann, Katharine Turner, Benjamin Eltzner, Stephan Tillmann, Fariza Rashid, Vanessa Robins, and Lamiae Azizi for many useful discussions at various stages of this project. FR and PY gratefully acknowledge Matthias Weiss (Experimental Physics I, University of Bayreuth, Germany) for granting access to cell culture and laboratories, as well as funding consumables and the fruitful discussion that contributed to this work. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","department":[{"_id":"HeEd"}],"external_id":{"pmid":["41604421"]},"article_number":"e1013890","scopus_import":"1","author":[{"full_name":"Bleile, Yossi","last_name":"Bleile","orcid":"0000-0002-4861-9174","id":"920a7385-7995-11ef-9bfd-8c434cd8f3c2","first_name":"Yossi"},{"first_name":"Pooja","last_name":"Yadav","full_name":"Yadav, Pooja"},{"first_name":"Patrice","full_name":"Koehl, Patrice","last_name":"Koehl"},{"first_name":"Florian","full_name":"Rehfeldt, Florian","last_name":"Rehfeldt"}],"OA_type":"gold","date_published":"2026-01-28T00:00:00Z","_id":"21115","language":[{"iso":"eng"}],"date_updated":"2026-06-11T11:51:13Z","quality_controlled":"1","ddc":["000"],"year":"2026","related_material":{"link":[{"url":"https://github.com/yossibokorbleile/correa","relation":"software"}]},"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"01","status":"public","PlanS_conform":"1","corr_author":"1","title":"Persistence diagrams as morphological signatures of cells: A method to measure and compare cells within a population","license":"https://creativecommons.org/licenses/by/4.0/","volume":22},{"publisher":"Institute of Science and Technology Austria","date_created":"2026-01-30T11:04:14Z","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","month":"01","year":"2026","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","date_updated":"2026-02-12T12:58:00Z","oa_version":"Published Version","doi":"10.15479/AT-ISTA-21116","date_published":"2026-01-02T00:00:00Z","_id":"21116","file":[{"relation":"main_file","content_type":"text/plain","access_level":"open_access","file_size":1201,"date_created":"2026-01-30T11:00:24Z","date_updated":"2026-01-30T11:00:24Z","creator":"llayanaf","file_id":"21117","checksum":"0b79be6229f2ad9ac117ef00fc4f5c0e","file_name":"README.txt","success":1},{"access_level":"open_access","content_type":"application/zip","relation":"main_file","date_created":"2026-01-30T11:00:36Z","file_size":572403,"success":1,"file_name":"Supplementary_Tables.zip","checksum":"a3cda72e4177fa1e5d3f0f6a88f8a79b","date_updated":"2026-01-30T11:00:36Z","file_id":"21118","creator":"llayanaf"},{"file_size":19054553,"date_created":"2026-01-30T11:00:48Z","content_type":"application/zip","relation":"main_file","access_level":"open_access","creator":"llayanaf","file_id":"21119","date_updated":"2026-01-30T11:00:48Z","checksum":"efb5b64698d6ca9e7b675204f6fc1c29","file_name":"Supplementary_Datasets.zip","success":1},{"file_size":4575,"date_created":"2026-01-30T11:00:56Z","relation":"main_file","content_type":"application/zip","access_level":"open_access","checksum":"254e050f648e9783ba8fe11adb3b49db","success":1,"file_name":"Perl_scripts.zip","creator":"llayanaf","file_id":"21120","date_updated":"2026-01-30T11:00:56Z"}],"abstract":[{"text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analyzed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find that the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on Muller element F (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes.","lang":"eng"}],"title":"Research Data for \"Causes and consequences of sex-chromosome turnovers in Diptera\"","author":[{"orcid":"0000-0002-1253-6297","id":"02814589-eb8f-11eb-b029-a70074f3f18f","first_name":"Lorena Alexandra","full_name":"Layana Franco, Lorena Alexandra","last_name":"Layana Franco"},{"first_name":"Melissa A","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A","last_name":"Toups"},{"first_name":"Beatriz","orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz","last_name":"Vicoso"}],"department":[{"_id":"BeVi"}],"oa":1,"type":"research_data","article_processing_charge":"No","citation":{"ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Research Data for ‘Causes and consequences of sex-chromosome turnovers in Diptera.’” Institute of Science and Technology Austria, 2026.","apa":"Layana Franco, L. A., Toups, M. A., &#38; Vicoso, B. (2026). Research Data for “Causes and consequences of sex-chromosome turnovers in Diptera.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21116\">https://doi.org/10.15479/AT-ISTA-21116</a>","ista":"Layana Franco LA, Toups MA, Vicoso B. 2026. Research Data for ‘Causes and consequences of sex-chromosome turnovers in Diptera’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21116\">10.15479/AT-ISTA-21116</a>.","mla":"Layana Franco, Lorena Alexandra, et al. <i>Research Data for “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21116\">10.15479/AT-ISTA-21116</a>.","chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Research Data for ‘Causes and Consequences of Sex-Chromosome Turnovers in Diptera.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21116\">https://doi.org/10.15479/AT-ISTA-21116</a>.","short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, (2026).","ama":"Layana Franco LA, Toups MA, Vicoso B. Research Data for “Causes and consequences of sex-chromosome turnovers in Diptera.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21116\">10.15479/AT-ISTA-21116</a>"},"corr_author":"1","file_date_updated":"2026-01-30T11:00:56Z","keyword":["Schizophora","sex chromosomes","sex-chromosome turnover","Diptera","genomic features","out-of-X movement."],"day":"2","status":"public"},{"title":"Hypocoercivity meets lifts","volume":20,"arxiv":1,"page":"34-55","status":"public","month":"02","year":"2026","language":[{"iso":"eng"}],"date_updated":"2026-02-16T10:02:47Z","quality_controlled":"1","_id":"21132","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2412.10890","open_access":"1"}],"date_published":"2026-02-01T00:00:00Z","scopus_import":"1","external_id":{"arxiv":["2412.10890"]},"OA_type":"green","author":[{"first_name":"Giovanni","id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1","last_name":"Brigati","full_name":"Brigati, Giovanni"},{"full_name":"Lörler, Francis","last_name":"Lörler","first_name":"Francis"},{"first_name":"Lihan","full_name":"Wang, Lihan","last_name":"Wang"}],"project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"acknowledgement":"We would like to thank Andreas Eberle and Gabriel Stoltz for many helpful discussions. GB\r\nhas received funding from the European Union Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 101034413. FL wurde gefördert durch die Deutsche Forschungsgemeinschaft (DFG) im Rahmen der Exzellenzstrategie des Bundes und der Länder – GZ2047/1, Projekt-ID 390685813. LW is supported by the National Science Foundation via grant DMS-2407166. He is also indebted to the Mathematical Sciences department at Carnegie Mellon University for partly supporting his visit to Europe in July 2024. Part of this work was completed when GB and LW were visiting the Institute for Applied Mathematics in Bonn. GB and LW would like to thank IAM for their hospitality.","department":[{"_id":"JaMa"}],"ec_funded":1,"article_processing_charge":"No","type":"journal_article","oa":1,"citation":{"ama":"Brigati G, Lörler F, Wang L. Hypocoercivity meets lifts. <i>Kinetic and Related Models</i>. 2026;20:34-55. doi:<a href=\"https://doi.org/10.3934/krm.2025020\">10.3934/krm.2025020</a>","short":"G. Brigati, F. Lörler, L. Wang, Kinetic and Related Models 20 (2026) 34–55.","chicago":"Brigati, Giovanni, Francis Lörler, and Lihan Wang. “Hypocoercivity Meets Lifts.” <i>Kinetic and Related Models</i>. American Institute of Mathematical Sciences, 2026. <a href=\"https://doi.org/10.3934/krm.2025020\">https://doi.org/10.3934/krm.2025020</a>.","apa":"Brigati, G., Lörler, F., &#38; Wang, L. (2026). Hypocoercivity meets lifts. <i>Kinetic and Related Models</i>. American Institute of Mathematical Sciences. <a href=\"https://doi.org/10.3934/krm.2025020\">https://doi.org/10.3934/krm.2025020</a>","ista":"Brigati G, Lörler F, Wang L. 2026. Hypocoercivity meets lifts. Kinetic and Related Models. 20, 34–55.","mla":"Brigati, Giovanni, et al. “Hypocoercivity Meets Lifts.” <i>Kinetic and Related Models</i>, vol. 20, American Institute of Mathematical Sciences, 2026, pp. 34–55, doi:<a href=\"https://doi.org/10.3934/krm.2025020\">10.3934/krm.2025020</a>.","ieee":"G. Brigati, F. Lörler, and L. Wang, “Hypocoercivity meets lifts,” <i>Kinetic and Related Models</i>, vol. 20. American Institute of Mathematical Sciences, pp. 34–55, 2026."},"day":"01","OA_place":"repository","intvolume":"        20","publisher":"American Institute of Mathematical Sciences","article_type":"original","date_created":"2026-02-01T23:01:43Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","publication_identifier":{"issn":["1937-5093"],"eissn":["1937-5077"]},"doi":"10.3934/krm.2025020","abstract":[{"text":"We unify the variational hypocoercivity framework established by D. Albritton, S. Armstrong, J.-C. Mourrat, and M. Novack [2], with the notion of second-order lifts of reversible diffusion processes, recently introduced by A. Eberle and the second author [30]. We give an abstract, yet fully constructive, presentation of the theory, so that it can be applied to a large class of linear kinetic equations. As this hypocoercivity technique does not twist the reference norm, we can recover accurate and sharp convergence rates in various models. Among those, adaptive Langevin dynamics (ALD) is discussed in full detail and we show that for near-quadratic potentials, with suitable choices of parameters, it is a near-optimal second-order lift of the overdamped Langevin dynamics. As a further consequence, we observe that the Generalised Langevin Equation (GLE) is also a second-order lift, as the standard (kinetic) Langevin dynamics are, of the overdamped Langevin dynamics. Then, convergence of (GLE) cannot exceed ballistic speed, i.e. the square root of the rate of the overdamped regime. We illustrate this phenomenon with explicit computations in a benchmark Gaussian case.","lang":"eng"}],"publication":"Kinetic and Related Models","publication_status":"epub_ahead"},{"_id":"21133","date_published":"2026-01-08T00:00:00Z","quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-02-16T08:43:24Z","year":"2026","ddc":["000"],"conference":{"name":"CPP: Conference on Certified Programs and Proofs","start_date":"2026-01-12","end_date":"2026-01-13","location":"Rennes, France"},"month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","page":"339-352","title":"A recipe for modular verification of generic tree traversals","file":[{"date_updated":"2026-02-16T08:40:29Z","creator":"dernst","file_id":"21225","checksum":"7df99991493e907d83a197151f378e3e","success":1,"file_name":"2026_CPP_Elbeheiry.pdf","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":811872,"date_created":"2026-02-16T08:40:29Z"}],"publication":"Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs","abstract":[{"lang":"eng","text":"Data structures based on trees and tree traversals are ubiquitous in computer systems. Many low-level programs, including some implementations of critical systems like page tables and the web browser DOM, rely on generic tree-traversal functions that traverse tree nodes in a pre-determined order, applying a client-provided operation to each visited node. Developing a general approach to specifying and verifying such traversals is tricky since the client-provided per-node operation can be stateful and may potentially depend on or modify the structure of the tree being traversed.\r\nIn this paper, we present a recipe for (semi-)automated verification of such generic, stateful tree traversals. Our recipe is (a) general: it applies to a range of tree traversals, in particular, pre-, post- and in-order depth-first traversals; (b) modular: parts of a traversal’s proof can be reused in verifying other similar traversals; (c) expressive: using the specification of a tree traversal, we can verify clients that use the traversal in a variety of different ways; and (d) automatable: many proof obligations can be discharged automatically.\r\nAt the heart of our recipe is a novel use of tree zippers to represent a logical abstraction of the tree traversal state, and zipper transitions as an abstraction of traversal steps. We realize our recipe in the RefinedC framework in Rocq, which allows us to verify a number of different tree traversals and their clients written in C."}],"publication_status":"published","doi":"10.1145/3779031.3779110","oa_version":"Published Version","publication_identifier":{"isbn":["9798400723414"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-01T23:01:43Z","publisher":"Association for Computing Machinery","day":"08","OA_place":"publisher","file_date_updated":"2026-02-16T08:40:29Z","citation":{"mla":"Elbeheiry, Laila, et al. “A Recipe for Modular Verification of Generic Tree Traversals.” <i>Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs</i>, Association for Computing Machinery, 2026, pp. 339–52, doi:<a href=\"https://doi.org/10.1145/3779031.3779110\">10.1145/3779031.3779110</a>.","ista":"Elbeheiry L, Sammler MJ, Krebbers R, Dreyer D, Garg D. 2026. A recipe for modular verification of generic tree traversals. Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs. CPP: Conference on Certified Programs and Proofs, 339–352.","apa":"Elbeheiry, L., Sammler, M. J., Krebbers, R., Dreyer, D., &#38; Garg, D. (2026). A recipe for modular verification of generic tree traversals. In <i>Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs</i> (pp. 339–352). Rennes, France: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3779031.3779110\">https://doi.org/10.1145/3779031.3779110</a>","ieee":"L. Elbeheiry, M. J. Sammler, R. Krebbers, D. Dreyer, and D. Garg, “A recipe for modular verification of generic tree traversals,” in <i>Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs</i>, Rennes, France, 2026, pp. 339–352.","ama":"Elbeheiry L, Sammler MJ, Krebbers R, Dreyer D, Garg D. A recipe for modular verification of generic tree traversals. In: <i>Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs</i>. Association for Computing Machinery; 2026:339-352. doi:<a href=\"https://doi.org/10.1145/3779031.3779110\">10.1145/3779031.3779110</a>","short":"L. Elbeheiry, M.J. Sammler, R. Krebbers, D. Dreyer, D. Garg, in:, Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs, Association for Computing Machinery, 2026, pp. 339–352.","chicago":"Elbeheiry, Laila, Michael Joachim Sammler, Robbert Krebbers, Derek Dreyer, and Deepak Garg. “A Recipe for Modular Verification of Generic Tree Traversals.” In <i>Proceedings of the 15th ACM SIGPLAN International Conference on Certified Programs and Proofs</i>, 339–52. Association for Computing Machinery, 2026. <a href=\"https://doi.org/10.1145/3779031.3779110\">https://doi.org/10.1145/3779031.3779110</a>."},"article_processing_charge":"No","type":"conference","oa":1,"acknowledgement":"We thank the anonymous reviewers for their insightful suggestions. This research is supported in part by generous awards from Android Security’s ASPIRE program and from Google Research. The third author is supported, in part, by ERC grant COCONUT (grant no. 101171349), funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.","department":[{"_id":"MiSa"}],"OA_type":"gold","author":[{"first_name":"Laila","full_name":"Elbeheiry, Laila","last_name":"Elbeheiry"},{"first_name":"Michael Joachim","id":"510d3901-2a03-11ee-914d-d9ae9011f0a7","last_name":"Sammler","full_name":"Sammler, Michael Joachim"},{"first_name":"Robbert","last_name":"Krebbers","full_name":"Krebbers, Robbert"},{"full_name":"Dreyer, Derek","last_name":"Dreyer","first_name":"Derek"},{"full_name":"Garg, Deepak","last_name":"Garg","first_name":"Deepak"}],"scopus_import":"1"},{"intvolume":"     15752","OA_place":"repository","day":"01","citation":{"mla":"Baig, Mirza Ahad, and Krzysztof Z. Pietrzak. “On the (in)Security of Proofs-of-Space Based Longest-Chain Blockchains.” <i>29th International Conference on Financial Cryptography and Data Security</i>, vol. 15752, Springer Nature, 2026, pp. 127–42, doi:<a href=\"https://doi.org/10.1007/978-3-032-07035-7_8\">10.1007/978-3-032-07035-7_8</a>.","ista":"Baig MA, Pietrzak KZ. 2026. On the (in)security of Proofs-of-space based longest-chain blockchains. 29th International Conference on Financial Cryptography and Data Security. FC: Financial Cryptography and Data Security, LNCS, vol. 15752, 127–142.","apa":"Baig, M. A., &#38; Pietrzak, K. Z. (2026). On the (in)security of Proofs-of-space based longest-chain blockchains. In <i>29th International Conference on Financial Cryptography and Data Security</i> (Vol. 15752, pp. 127–142). Miyakojima, Japan: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-07035-7_8\">https://doi.org/10.1007/978-3-032-07035-7_8</a>","ieee":"M. A. Baig and K. Z. Pietrzak, “On the (in)security of Proofs-of-space based longest-chain blockchains,” in <i>29th International Conference on Financial Cryptography and Data Security</i>, Miyakojima, Japan, 2026, vol. 15752, pp. 127–142.","ama":"Baig MA, Pietrzak KZ. On the (in)security of Proofs-of-space based longest-chain blockchains. In: <i>29th International Conference on Financial Cryptography and Data Security</i>. Vol 15752. Springer Nature; 2026:127-142. doi:<a href=\"https://doi.org/10.1007/978-3-032-07035-7_8\">10.1007/978-3-032-07035-7_8</a>","short":"M.A. Baig, K.Z. Pietrzak, in:, 29th International Conference on Financial Cryptography and Data Security, Springer Nature, 2026, pp. 127–142.","chicago":"Baig, Mirza Ahad, and Krzysztof Z Pietrzak. “On the (in)Security of Proofs-of-Space Based Longest-Chain Blockchains.” In <i>29th International Conference on Financial Cryptography and Data Security</i>, 15752:127–42. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-07035-7_8\">https://doi.org/10.1007/978-3-032-07035-7_8</a>."},"oa":1,"type":"conference","article_processing_charge":"No","department":[{"_id":"KrPi"}],"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85.","project":[{"name":"Security and Privacy by Design for Complex Systems","grant_number":"F8509","_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1"}],"author":[{"id":"3EDE6DE4-AA5A-11E9-986D-341CE6697425","first_name":"Mirza Ahad","last_name":"Baig","full_name":"Baig, Mirza Ahad"},{"orcid":"0000-0002-9139-1654","first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Pietrzak, Krzysztof Z","last_name":"Pietrzak"}],"OA_type":"green","external_id":{"arxiv":["2505.14891"]},"scopus_import":"1","publication_status":"published","abstract":[{"text":"The Nakamoto consensus protocol underlying the Bitcoin blockchain uses proof of work as a voting mechanism. Honest miners who contribute hashing power towards securing the chain try to extend the longest chain they are aware of. Despite its simplicity, Nakamoto consensus achieves meaningful security guarantees assuming that at any point in time, a majority of the hashing power is controlled by honest parties. This also holds under “resource variability”, i.e., if the total hashing power varies greatly over time.\r\nProofs of space (PoSpace) have been suggested as a more sustainable replacement for proofs of work. Unfortunately, no construction of a “longest-chain” blockchain based on PoSpace, that is secure under dynamic availability, is known. In this work, we prove that without additional assumptions no such protocol exists. We exactly quantify this impossibility result by proving a bound on the length of the fork required for double spending as a function of the adversarial capabilities. This bound holds for any chain selection rule, and we also show a chain selection rule (albeit a very strange one) that almost matches this bound.\r\nThe Nakamoto consensus protocol underlying the Bitcoin blockchain uses proof of work as a voting mechanism. Honest miners who contribute hashing power towards securing the chain try to extend the longest chain they are aware of. Despite its simplicity, Nakamoto consensus achieves meaningful security guarantees assuming that at any point in time, a majority of the hashing power is controlled by honest parties. This also holds under “resource variability”, i.e., if the total hashing power varies greatly over time.\r\n\r\nProofs of space (PoSpace) have been suggested as a more sustainable replacement for proofs of work. Unfortunately, no construction of a “longest-chain” blockchain based on PoSpace, that is secure under dynamic availability, is known. In this work, we prove that without additional assumptions no such protocol exists. We exactly quantify this impossibility result by proving a bound on the length of the fork required for double spending as a function of the adversarial capabilities. This bound holds for any chain selection rule, and we also show a chain selection rule (albeit a very strange one) that almost matches this bound.\r\n\r\nConcretely, we consider a security game in which the honest parties at any point control 0 > 1\r\n times more space than the adversary. The adversary can change the honest space by a factor 1+- E with every block (dynamic availability), and “replotting” the space (which allows answering two challenges using the same space) takes as much time as p blocks.\r\nWe prove that no matter what chain selection rule is used, in this game the adversary can create a fork of length o^2 . p/E that will be picked as the winner by the chain selection rule.\r\nWe also provide an upper bound that matches the lower bound up to a factor o. There exists a chain selection rule (albeit a very strange one) which in the above game requires forks of length at least o . p/E\r\nOur results show the necessity of additional assumptions to create a secure PoSpace based longest-chain blockchain. The Chia network in addition to PoSpace uses a verifiable delay function. Our bounds show that an additional primitive like that is necessary.","lang":"eng"}],"publication":"29th International Conference on Financial Cryptography and Data Security","doi":"10.1007/978-3-032-07035-7_8","oa_version":"Preprint","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783032070340"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-01T23:01:43Z","publisher":"Springer Nature","status":"public","page":"127-142","arxiv":1,"corr_author":"1","volume":15752,"title":"On the (in)security of Proofs-of-space based longest-chain blockchains","date_published":"2026-01-01T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2505.14891","open_access":"1"}],"_id":"21134","alternative_title":["LNCS"],"quality_controlled":"1","date_updated":"2026-04-15T08:45:18Z","language":[{"iso":"eng"}],"conference":{"location":"Miyakojima, Japan","end_date":"2025-04-18","name":"FC: Financial Cryptography and Data Security","start_date":"2025-04-14"},"year":"2026","month":"01","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"21651"}]}},{"oa_version":"Preprint","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783032139603"]},"doi":"10.1007/978-3-032-13961-0_26","publication_status":"published","publication":"1st International Workshop on Efficient Medical Artificial Intelligence","abstract":[{"text":"Three-dimensional (3D) microscopy data is often anisotropic with significantly lower resolution (up to 8x) along the z axis than along the xy axes. Computationally generating plausible isotropic resolution from anisotropic imaging data would benefit the visual analysis of large-scale volumes. This paper proposes niiv, a self-supervised method for isotropic reconstruction of 3D microscopy data that can quickly produce images at arbitrary output resolutions. The representation embeds a learned latent code within a neural field that describes the implicit higher-resolution isotropic image region. We use an attention-guided latent interpolation approach, which allows flexible information exchange over a local latent neighborhood. Under isotropic volume assumptions, we self-supervise this representation on low-/high-resolution lateral image pairs to reconstruct an isotropic volume from low-resolution axial images. We evaluate our method on simulated and real anisotropic electron (EM) and light microscopy (LM) data. Compared to diffusion-based baselines, niiv shows improved reconstruction quality (+1 dB PSNR) and is over three orders of magnitude faster (1,000x) to infer. Specifically, niiv reconstructs a 128^3 voxel volume in 2/10th of a second, renderable at varying (continuous) high resolutions for display. Our code is available at https://github.com/jakobtroidl/niiv-miccai.","lang":"eng"}],"publisher":"Springer Nature","date_created":"2026-02-01T23:01:44Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"type":"conference","article_processing_charge":"No","citation":{"chicago":"Troidl, Jakob, Yiqing Liang, Johanna Beyer, Mojtaba Tavakoli, Johann G Danzl, Markus Hadwiger, Hanspeter Pfister, and James Tompkin. “Niiv: Interactive Self-Supervised Neural Implicit Isotropic Volume Reconstruction.” In <i>1st International Workshop on Efficient Medical Artificial Intelligence</i>, 16318:257–67. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-13961-0_26\">https://doi.org/10.1007/978-3-032-13961-0_26</a>.","short":"J. Troidl, Y. Liang, J. Beyer, M. Tavakoli, J.G. Danzl, M. Hadwiger, H. Pfister, J. Tompkin, in:, 1st International Workshop on Efficient Medical Artificial Intelligence, Springer Nature, 2026, pp. 257–267.","ama":"Troidl J, Liang Y, Beyer J, et al. niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction. In: <i>1st International Workshop on Efficient Medical Artificial Intelligence</i>. Vol 16318. Springer Nature; 2026:257-267. doi:<a href=\"https://doi.org/10.1007/978-3-032-13961-0_26\">10.1007/978-3-032-13961-0_26</a>","ieee":"J. Troidl <i>et al.</i>, “niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction,” in <i>1st International Workshop on Efficient Medical Artificial Intelligence</i>, Daejeon, South Korea, 2026, vol. 16318, pp. 257–267.","apa":"Troidl, J., Liang, Y., Beyer, J., Tavakoli, M., Danzl, J. G., Hadwiger, M., … Tompkin, J. (2026). niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction. In <i>1st International Workshop on Efficient Medical Artificial Intelligence</i> (Vol. 16318, pp. 257–267). Daejeon, South Korea: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-13961-0_26\">https://doi.org/10.1007/978-3-032-13961-0_26</a>","ista":"Troidl J, Liang Y, Beyer J, Tavakoli M, Danzl JG, Hadwiger M, Pfister H, Tompkin J. 2026. niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction. 1st International Workshop on Efficient Medical Artificial Intelligence. EMA4MICCAI: Efficient Medical Artificial Intelligence, LNCS, vol. 16318, 257–267.","mla":"Troidl, Jakob, et al. “Niiv: Interactive Self-Supervised Neural Implicit Isotropic Volume Reconstruction.” <i>1st International Workshop on Efficient Medical Artificial Intelligence</i>, vol. 16318, Springer Nature, 2026, pp. 257–67, doi:<a href=\"https://doi.org/10.1007/978-3-032-13961-0_26\">10.1007/978-3-032-13961-0_26</a>."},"OA_place":"repository","day":"03","intvolume":"     16318","scopus_import":"1","author":[{"first_name":"Jakob","last_name":"Troidl","full_name":"Troidl, Jakob"},{"full_name":"Liang, Yiqing","last_name":"Liang","first_name":"Yiqing"},{"first_name":"Johanna","full_name":"Beyer, Johanna","last_name":"Beyer"},{"full_name":"Tavakoli, Mojtaba","last_name":"Tavakoli","first_name":"Mojtaba","orcid":"0000-0002-7667-6854","id":"3A0A06F4-F248-11E8-B48F-1D18A9856A87"},{"id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8559-3973","first_name":"Johann G","full_name":"Danzl, Johann G","last_name":"Danzl"},{"full_name":"Hadwiger, Markus","last_name":"Hadwiger","first_name":"Markus"},{"full_name":"Pfister, Hanspeter","last_name":"Pfister","first_name":"Hanspeter"},{"last_name":"Tompkin","full_name":"Tompkin, James","first_name":"James"}],"OA_type":"green","acknowledgement":"This work was supported by NIH grants 1U01NS132158 and R01HD104969. We thank the reviewers for their constructive feedback.","department":[{"_id":"JoDa"}],"language":[{"iso":"eng"}],"date_updated":"2026-02-16T08:50:50Z","quality_controlled":"1","alternative_title":["LNCS"],"date_published":"2026-01-03T00:00:00Z","_id":"21135","main_file_link":[{"url":"https://doi.org/10.1101/2024.09.07.611785","open_access":"1"}],"related_material":{"link":[{"url":"https://github.com/jakobtroidl/niiv-miccai","relation":"software"}]},"month":"01","conference":{"start_date":"2025-09-23","name":"EMA4MICCAI: Efficient Medical Artificial Intelligence","end_date":"2025-09-23","location":"Daejeon, South Korea"},"year":"2026","page":"257-267","status":"public","title":"niiv: Interactive Self-supervised Neural Implicit Isotropic Volume Reconstruction","volume":16318},{"license":"https://creativecommons.org/licenses/by-sa/4.0/","title":"Data associated with Keratins coordinate tissue spreading ","corr_author":"1","status":"public","acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"tmp":{"image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)"},"has_accepted_license":"1","month":"3","year":"2026","date_updated":"2026-06-10T09:44:10Z","date_published":"2026-03-24T00:00:00Z","_id":"21137","author":[{"orcid":"0000-0001-8421-5508","id":"2C0B105C-F248-11E8-B48F-1D18A9856A87","first_name":"Suyash","last_name":"Naik","full_name":"Naik, Suyash"}],"ec_funded":1,"department":[{"_id":"GradSch"},{"_id":"CaHe"},{"_id":"EdHa"}],"acknowledgement":"We thank all members of the Heisenberg, Henkes, and Hannezo groups for their support. We are also grateful to the Imaging and Optics, Scientific Computing, Life Science Support, and Cryo-Electron Microscopy facilities at ISTA for their technical assistance and support. Numerical simulations were performed using the computational resources from Lorentz Institute and the Academic Leiden Interdisciplinary Cluster Environment (ALICE) provided by Leiden University, and from PMMH provided by Sorbonne Université. S.N has received funding from European Union’s Horizon 2020 research and innovation programme (grant agreement No. 665385). This work was supported by the Austrian Science Fund (FWF) under projects PAT5044023 and W1250 awarded to C.-P.H.","project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","call_identifier":"H2020"},{"name":"Keratins in epithelial tissue spreading","grant_number":"PAT 5044023","_id":"8f060199-16d5-11f0-9cad-f3253b266c46"},{"call_identifier":"FWF","grant_number":"W1250-B20","_id":"252C3B08-B435-11E9-9278-68D0E5697425","name":"Nano-Analytics of Cellular Systems"}],"citation":{"ama":"Naik S. Data associated with Keratins coordinate tissue spreading . 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>","short":"S. Naik, (2026).","chicago":"Naik, Suyash. “Data Associated with Keratins Coordinate Tissue Spreading .” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>.","mla":"Naik, Suyash. <i>Data Associated with Keratins Coordinate Tissue Spreading </i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>.","apa":"Naik, S. (2026). Data associated with Keratins coordinate tissue spreading . Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>","ista":"Naik S. 2026. Data associated with Keratins coordinate tissue spreading , Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>.","ieee":"S. Naik, “Data associated with Keratins coordinate tissue spreading .” Institute of Science and Technology Austria, 2026."},"oa":1,"type":"research_data","article_processing_charge":"No","OA_place":"repository","file_date_updated":"2026-03-24T07:21:43Z","day":"24","date_created":"2026-02-04T16:38:02Z","publisher":"Institute of Science and Technology Austria","contributor":[{"first_name":"Yann-Edwin","contributor_type":"researcher","last_name":"Keta"},{"last_name":"Henkes","contributor_type":"supervisor","first_name":"Silke "},{"contributor_type":"supervisor","last_name":"Heisenberg","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J"},{"last_name":"Hannezo","contributor_type":"supervisor","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B"}],"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","oa_version":"Published Version","file":[{"description":"Python3 library written in C++20 to integrate vertex models. Please read the readme at https://github.com/yketa/cells/blob/main/README.md for detailed instructions for installation and usage of the code in this repository. ","content_type":"application/zip","relation":"main_file","access_level":"open_access","title":"Cell git repository","file_size":725916,"date_created":"2026-03-16T11:51:10Z","checksum":"5d1fda7e410f24c311fcf6bcf725698f","file_name":"cells-main.zip","date_updated":"2026-03-16T11:51:10Z","creator":"snaik","file_id":"21461"},{"access_level":"open_access","relation":"main_file","content_type":"application/x-zip-compressed","date_created":"2026-03-18T14:52:02Z","file_size":282168895,"date_updated":"2026-03-18T14:52:02Z","file_id":"21464","creator":"snaik","file_name":"DevBranchDataRepo.zip","success":1,"checksum":"ee350c8eaed99f3ca348c47c8b190d3c"},{"success":1,"file_name":"ReadMe.md","checksum":"1ecaf2c1a2ce8ff9c75a128cc02d0b8f","date_updated":"2026-03-18T15:01:32Z","file_id":"21466","creator":"snaik","access_level":"open_access","content_type":"text/markdown","relation":"main_file","date_created":"2026-03-18T15:01:32Z","file_size":2231},{"file_id":"21467","creator":"snaik","date_updated":"2026-03-18T15:12:57Z","file_name":"PaperSchematics.svg","success":1,"checksum":"da9a4687e5144b61a64ca341f922046a","date_created":"2026-03-18T15:12:57Z","file_size":1951210,"access_level":"open_access","relation":"main_file","content_type":"image/svg+xml"},{"date_updated":"2026-03-21T03:37:43Z","file_id":"21468","creator":"snaik","success":1,"file_name":"maxwell_sketch.tex","checksum":"9ac1054b16c212c6f34d402dce2c80e0","access_level":"open_access","relation":"main_file","content_type":"application/octet-stream","date_created":"2026-03-21T03:37:43Z","file_size":1897},{"success":1,"file_name":"DataRepo.zip","checksum":"7c9ecf78e2593b3830d96fa94baa08df","file_id":"21495","creator":"snaik","date_updated":"2026-03-24T07:21:43Z","date_created":"2026-03-24T07:21:43Z","file_size":749368723,"access_level":"open_access","content_type":"application/x-zip-compressed","relation":"main_file"}],"doi":"10.15479/AT-ISTA-21137"},{"article_processing_charge":"No","type":"conference","oa":1,"citation":{"ieee":"P. Arkhipov and V. Kolmogorov, “Faster algorithms for packing forests in graphs and related problems,” in <i>Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Vancouver, Canada, 2026, pp. 4023–4042.","apa":"Arkhipov, P., &#38; Kolmogorov, V. (2026). Faster algorithms for packing forests in graphs and related problems. In <i>Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (pp. 4023–4042). Vancouver, Canada: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611978971.148\">https://doi.org/10.1137/1.9781611978971.148</a>","ista":"Arkhipov P, Kolmogorov V. 2026. Faster algorithms for packing forests in graphs and related problems. Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 4023–4042.","mla":"Arkhipov, Pavel, and Vladimir Kolmogorov. “Faster Algorithms for Packing Forests in Graphs and Related Problems.” <i>Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Society for Industrial and Applied Mathematics, 2026, pp. 4023–42, doi:<a href=\"https://doi.org/10.1137/1.9781611978971.148\">10.1137/1.9781611978971.148</a>.","chicago":"Arkhipov, Pavel, and Vladimir Kolmogorov. “Faster Algorithms for Packing Forests in Graphs and Related Problems.” In <i>Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 4023–42. Society for Industrial and Applied Mathematics, 2026. <a href=\"https://doi.org/10.1137/1.9781611978971.148\">https://doi.org/10.1137/1.9781611978971.148</a>.","short":"P. Arkhipov, V. Kolmogorov, in:, Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2026, pp. 4023–4042.","ama":"Arkhipov P, Kolmogorov V. Faster algorithms for packing forests in graphs and related problems. In: <i>Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for Industrial and Applied Mathematics; 2026:4023-4042. doi:<a href=\"https://doi.org/10.1137/1.9781611978971.148\">10.1137/1.9781611978971.148</a>"},"day":"07","OA_place":"repository","external_id":{"arxiv":["2409.20314"]},"OA_type":"green","author":[{"id":"b25f2ab2-1fed-11ee-8599-fe02d211784f","first_name":"Pavel","last_name":"Arkhipov","full_name":"Arkhipov, Pavel"},{"last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"}],"department":[{"_id":"VlKo"}],"oa_version":"Preprint","publication_identifier":{"eisbn":["9781611978971"]},"doi":"10.1137/1.9781611978971.148","publication":"Proceedings of the 2026 Annual ACM-SIAM Symposium on Discrete Algorithms","abstract":[{"text":"We consider several problems related to packing forests in graphs. The first one is to find k edge-disjoint forests in a directed graph G of maximal size such that the indegree of each vertex in these forests is at most k. We describe a min-max characterization for this problem and show that it can be solved in almost linear time for fixed k, extending the algorithm of [Gabow, 1995]. Specifically, the complexity is O(kδm log n), where n, m are the number of vertices and edges in G respectively, and δ = max{1, k − kG}, where kG is the edge connectivity of the graph. Using our solution to this problem, we improve complexities for two existing applications:(1) k-forest problem: find k forests in an undirected graph G maximizing the number of edges in their union. We show how to solve this problem in O(k3 min{kn, m} log2 n + k · MAXFLOW(m, m) log n) time, breaking the Ok(n3/2) complexity barrier of previously known approaches.(2) Directed edge-connectivity augmentation problem: find a smallest set of directed edges whose addition to the given directed graph makes it strongly k-connected. We improve the deterministic complexity for this problem from O(kδ(m + δn) log n) [Gabow, STOC 1994] to O(kδm log n). A similar approach with the same complexity also works for the undirected version of the problem.","lang":"eng"}],"publication_status":"published","publisher":"Society for Industrial and Applied Mathematics","date_created":"2026-02-05T10:51:34Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"corr_author":"1","page":"4023-4042","status":"public","title":"Faster algorithms for packing forests in graphs and related problems","language":[{"iso":"eng"}],"date_updated":"2026-02-16T09:18:33Z","quality_controlled":"1","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2409.20314","open_access":"1"}],"_id":"21140","date_published":"2026-01-07T00:00:00Z","month":"01","year":"2026","conference":{"name":"SODA: Symposium on Discrete Algorithms","start_date":"2026-01-11","end_date":"2026-01-14","location":"Vancouver, Canada"}},{"month":"02","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"year":"2026","ddc":["530"],"quality_controlled":"1","date_updated":"2026-02-10T11:30:37Z","language":[{"iso":"eng"}],"_id":"21149","date_published":"2026-02-05T00:00:00Z","volume":136,"title":"Bottom-up analysis of rovibrational helical dichroism","corr_author":"1","arxiv":1,"PlanS_conform":"1","status":"public","date_created":"2026-02-06T10:53:17Z","publisher":"American Physical Society","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"abstract":[{"text":"We present a general theoretical framework for helical dichroism (HD), establishing an explicit link between chiral resolution and orbital angular momentum (OAM) exchange in light–matter interaction. Tracing microscopic mechanisms of the OAM transfer, we derive rotational selection rules, which establish that HD emerges only from the spin–orbit coupling of light, even for beams without the far-field OAM. Our findings refine the conditions for observing HD, provide a tool to re-examine the outcome of prior experiments, and guide future designs for chiral sensing with structured light.","lang":"eng"}],"publication":"Physical Review Letters","file":[{"date_updated":"2026-02-10T11:25:46Z","file_id":"21210","creator":"dernst","file_name":"2026_PhysicalReviewLetters_Hrast.pdf","success":1,"checksum":"805c929fff9fd4d0e733293eaace67b8","access_level":"open_access","content_type":"application/pdf","relation":"main_file","date_created":"2026-02-10T11:25:46Z","file_size":511312}],"publication_status":"published","doi":"10.1103/fkf1-1jml","OA_type":"hybrid","author":[{"first_name":"Mateja","id":"48dbb294-2a9c-11ef-905d-f56be71f0e5d","last_name":"Hrast","full_name":"Hrast, Mateja"},{"first_name":"Georgios","id":"d7b23d3a-9e21-11ec-b482-f76739596b95","last_name":"Koutentakis","full_name":"Koutentakis, Georgios"},{"full_name":"Maslov, Mikhail","last_name":"Maslov","first_name":"Mikhail","id":"2E65BB0E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4074-2570"},{"first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","last_name":"Lemeshko","full_name":"Lemeshko, Mikhail"}],"scopus_import":"1","article_number":"053204","external_id":{"arxiv":["2505.16393"]},"project":[{"name":"Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions","grant_number":"F100403","_id":"7c040762-9f16-11ee-852c-dd79eeee4ab3"}],"department":[{"_id":"MiLe"}],"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/F1004].","issue":"5","citation":{"ama":"Hrast M, Koutentakis G, Maslov M, Lemeshko M. Bottom-up analysis of rovibrational helical dichroism. <i>Physical Review Letters</i>. 2026;136(5). doi:<a href=\"https://doi.org/10.1103/fkf1-1jml\">10.1103/fkf1-1jml</a>","short":"M. Hrast, G. Koutentakis, M. Maslov, M. Lemeshko, Physical Review Letters 136 (2026).","chicago":"Hrast, Mateja, Georgios Koutentakis, Mikhail Maslov, and Mikhail Lemeshko. “Bottom-up Analysis of Rovibrational Helical Dichroism.” <i>Physical Review Letters</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/fkf1-1jml\">https://doi.org/10.1103/fkf1-1jml</a>.","mla":"Hrast, Mateja, et al. “Bottom-up Analysis of Rovibrational Helical Dichroism.” <i>Physical Review Letters</i>, vol. 136, no. 5, 053204, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/fkf1-1jml\">10.1103/fkf1-1jml</a>.","ista":"Hrast M, Koutentakis G, Maslov M, Lemeshko M. 2026. Bottom-up analysis of rovibrational helical dichroism. Physical Review Letters. 136(5), 053204.","apa":"Hrast, M., Koutentakis, G., Maslov, M., &#38; Lemeshko, M. (2026). Bottom-up analysis of rovibrational helical dichroism. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/fkf1-1jml\">https://doi.org/10.1103/fkf1-1jml</a>","ieee":"M. Hrast, G. Koutentakis, M. Maslov, and M. Lemeshko, “Bottom-up analysis of rovibrational helical dichroism,” <i>Physical Review Letters</i>, vol. 136, no. 5. American Physical Society, 2026."},"type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"intvolume":"       136","day":"05","file_date_updated":"2026-02-10T11:25:46Z","OA_place":"publisher"},{"PlanS_conform":"1","status":"public","volume":17,"title":"O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering","quality_controlled":"1","date_updated":"2026-02-12T14:34:24Z","language":[{"iso":"eng"}],"_id":"21158","date_published":"2026-01-27T00:00:00Z","month":"01","has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"year":"2026","ddc":["580"],"citation":{"mla":"Yang, Pengfang, et al. “O-GlcNAc and Phosphorylation Modifications on HtL1/FBA10 Regulate Wheat Vernalization for Flowering.” <i>Nature Communications</i>, vol. 17, 999, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-025-67734-0\">10.1038/s41467-025-67734-0</a>.","apa":"Yang, P., Liu, Y., Dong, Q., Miao, Y., Zhang, J., Xu, S., … Chong, K. (2026). O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-67734-0\">https://doi.org/10.1038/s41467-025-67734-0</a>","ista":"Yang P, Liu Y, Dong Q, Miao Y, Zhang J, Xu S, Zhao H, Niu Y, Zhang X, Xu Y, Guo Z, Xing L, Chong K. 2026. O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. Nature Communications. 17, 999.","ieee":"P. Yang <i>et al.</i>, “O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ama":"Yang P, Liu Y, Dong Q, et al. O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-025-67734-0\">10.1038/s41467-025-67734-0</a>","short":"P. Yang, Y. Liu, Q. Dong, Y. Miao, J. Zhang, S. Xu, H. Zhao, Y. Niu, X. Zhang, Y. Xu, Z. Guo, L. Xing, K. Chong, Nature Communications 17 (2026).","chicago":"Yang, Pengfang, Yangyang Liu, Qi Dong, Yuting Miao, Jianlong Zhang, Shujuan Xu, Hong Zhao, et al. “O-GlcNAc and Phosphorylation Modifications on HtL1/FBA10 Regulate Wheat Vernalization for Flowering.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-025-67734-0\">https://doi.org/10.1038/s41467-025-67734-0</a>."},"article_processing_charge":"Yes","type":"journal_article","oa":1,"intvolume":"        17","day":"27","OA_place":"publisher","file_date_updated":"2026-02-12T14:33:14Z","OA_type":"gold","author":[{"first_name":"Pengfang","last_name":"Yang","full_name":"Yang, Pengfang"},{"last_name":"Liu","full_name":"Liu, Yangyang","first_name":"Yangyang"},{"first_name":"Qi","full_name":"Dong, Qi","last_name":"Dong"},{"full_name":"Miao, Yuting","last_name":"Miao","first_name":"Yuting"},{"first_name":"Jianlong","full_name":"Zhang, Jianlong","last_name":"Zhang"},{"last_name":"Xu","full_name":"Xu, Shujuan","id":"9724dd9d-f591-11ee-bd51-e97ed0652286","first_name":"Shujuan"},{"full_name":"Zhao, Hong","last_name":"Zhao","first_name":"Hong"},{"first_name":"Yuda","full_name":"Niu, Yuda","last_name":"Niu"},{"full_name":"Zhang, Xueyong","last_name":"Zhang","first_name":"Xueyong"},{"first_name":"Yunyuan","full_name":"Xu, Yunyuan","last_name":"Xu"},{"full_name":"Guo, Zifeng","last_name":"Guo","first_name":"Zifeng"},{"full_name":"Xing, Lijing","last_name":"Xing","first_name":"Lijing"},{"full_name":"Chong, Kang","last_name":"Chong","first_name":"Kang"}],"article_number":"999","scopus_import":"1","external_id":{"pmid":["41455723"]},"department":[{"_id":"XiFe"}],"acknowledgement":"This work was supported by the Basic Science Center Project of National Natural Science Foundation of China (32388201) to K.C and the National Natural Science Foundation of China (31970331) to L.X. We thank Dr. Zhuang Lu, Dr. Bin Han and Ms. Jingquan Li (Plant Science Facility of the Institute of Botany, Chinese Academy of Sciences) for their technical assistance in LC-MS/MS assay, small molecule compound analysis and the subcellular localization assay, respectively. We thank Dr. Wei Luo and Dr. Dongfeng Liu for helpful discussions.","publication_identifier":{"eissn":["2041-1723"]},"oa_version":"Published Version","pmid":1,"file":[{"date_created":"2026-02-12T14:33:14Z","file_size":4685882,"access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_id":"21223","creator":"dernst","date_updated":"2026-02-12T14:33:14Z","success":1,"file_name":"2026_NatureComm_Yang.pdf","checksum":"9ae170ec70ba1ab56b6f1ffe67d1de7f"}],"publication":"Nature Communications","abstract":[{"text":"Vernalization-regulated flowering is vital for wheat yield and geographical distribution, and the diversity of flowering time genes is essential for the breeding of climate-resilient varieties. Sugars have long been recognized in regulating flowering; however, the intrinsic connection between carbohydrate metabolism and vernalization response remains largely unexplored. Here, we identify a fructose 1,6-bisphosphate aldolase (FBA) encoding gene, HtL1/FBA10, as a modulator of heading time variation based on a genome-wide association study utilizing wheat core germplasm collections. Evolutionary analysis shows a decrease in the proportion of haplotype-2 of HtL1, which is linked to delayed flowering, in Chinese and American wheat varieties compared to landraces. Vernalization reduces HtL1/FBA10 phosphorylation levels and  increases  its O-GlcNAcylation, which in turn enhances its enzymatic activity and facilitates VERNALIZATION 1 (VRN1) transcription by regulating histone acetylation at the VRN1 locus. Our findings provide mechanistic insights into the interplay between glucose metabolism and the epigenetic regulation of vernalization in winter wheat.","lang":"eng"}],"publication_status":"published","DOAJ_listed":"1","doi":"10.1038/s41467-025-67734-0","date_created":"2026-02-08T23:02:48Z","publisher":"Springer Nature","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"ddc":["510"],"year":"2026","month":"02","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","_id":"21159","date_published":"2026-02-01T00:00:00Z","language":[{"iso":"eng"}],"date_updated":"2026-02-16T09:55:17Z","quality_controlled":"1","title":"Counting perfect matchings in Dirac hypergraphs","volume":46,"status":"public","corr_author":"1","arxiv":1,"PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publisher":"Springer Nature","date_created":"2026-02-08T23:02:49Z","doi":"10.1007/s00493-025-00194-8","file":[{"relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_size":539646,"date_created":"2026-02-16T09:52:38Z","date_updated":"2026-02-16T09:52:38Z","creator":"dernst","file_id":"21228","checksum":"47b0031d90b0e6b9a843f422a1486089","file_name":"2026_Combinatorica_Kwan.pdf","success":1}],"publication":"Combinatorica","abstract":[{"lang":"eng","text":"One of the foundational theorems of extremal graph theory is Dirac’s theorem, which\r\nsays that if an n-vertex graph G has minimum degree at least n/2, then G has a\r\nHamilton cycle, and therefore a perfect matching (if n is even). Later work by Sárközy,\r\nSelkow and Szemerédi showed that in fact Dirac graphs have many Hamilton cycles\r\nand perfect matchings, culminating in a result of Cuckler and Kahn that gives a precise\r\ndescription of the numbers of Hamilton cycles and perfect matchings in a Dirac graph\r\nG (in terms of an entropy-like parameter of G). In this paper we extend Cuckler\r\nand Kahn’s result to perfect matchings in hypergraphs. For positive integers d < k,\r\nand for n divisible by k, let md (k, n) be the minimum d-degree that ensures the\r\nexistence of a perfect matching in an n-vertex k-uniform hypergraph. In general, it is\r\nan open question to determine (even asymptotically) the values of md (k, n), but we are\r\nnonetheless able to prove an analogue of the Cuckler–Kahn theorem, showing that if\r\nan n-vertex k-uniform hypergraph G has minimum d-degree at least (1+γ )md (k, n)\r\n(for any constantγ > 0), then the number of perfect matchings in G is controlled by\r\nan entropy-like parameter of G. This strengthens cruder estimates arising from work\r\nof Kang–Kelly–Kühn–Osthus–Pfenninger and Pham–Sah–Sawhney–Simkin."}],"publication_status":"published","publication_identifier":{"eissn":["1439-6912"],"issn":["0209-9683"]},"oa_version":"Published Version","department":[{"_id":"MaKw"},{"_id":"MoHe"}],"acknowledgement":"We would like to thank the referees for a number of helpful comments and suggestions, which have substantially improved the paper. Open access funding provided by Institute of Science and Technology (IST Austria).","article_number":"5","scopus_import":"1","external_id":{"arxiv":["2408.09589"]},"OA_type":"hybrid","author":[{"orcid":"0000-0002-4003-7567","first_name":"Matthew Alan","id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3","full_name":"Kwan, Matthew Alan","last_name":"Kwan"},{"full_name":"Safavi Hemami, Roodabeh","last_name":"Safavi Hemami","first_name":"Roodabeh","id":"72ed2640-8972-11ed-ae7b-f9c81ec75154"},{"id":"1917d194-076e-11ed-97cd-837255f88785","orcid":"0000-0002-2856-767X","first_name":"Yiting","last_name":"Wang","full_name":"Wang, Yiting"}],"day":"01","file_date_updated":"2026-02-16T09:52:38Z","OA_place":"publisher","intvolume":"        46","article_processing_charge":"Yes (via OA deal)","type":"journal_article","oa":1,"citation":{"ieee":"M. A. Kwan, R. Safavi Hemami, and Y. Wang, “Counting perfect matchings in Dirac hypergraphs,” <i>Combinatorica</i>, vol. 46. Springer Nature, 2026.","mla":"Kwan, Matthew Alan, et al. “Counting Perfect Matchings in Dirac Hypergraphs.” <i>Combinatorica</i>, vol. 46, 5, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s00493-025-00194-8\">10.1007/s00493-025-00194-8</a>.","ista":"Kwan MA, Safavi Hemami R, Wang Y. 2026. Counting perfect matchings in Dirac hypergraphs. Combinatorica. 46, 5.","apa":"Kwan, M. A., Safavi Hemami, R., &#38; Wang, Y. (2026). Counting perfect matchings in Dirac hypergraphs. <i>Combinatorica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00493-025-00194-8\">https://doi.org/10.1007/s00493-025-00194-8</a>","chicago":"Kwan, Matthew Alan, Roodabeh Safavi Hemami, and Yiting Wang. “Counting Perfect Matchings in Dirac Hypergraphs.” <i>Combinatorica</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00493-025-00194-8\">https://doi.org/10.1007/s00493-025-00194-8</a>.","ama":"Kwan MA, Safavi Hemami R, Wang Y. Counting perfect matchings in Dirac hypergraphs. <i>Combinatorica</i>. 2026;46. doi:<a href=\"https://doi.org/10.1007/s00493-025-00194-8\">10.1007/s00493-025-00194-8</a>","short":"M.A. Kwan, R. Safavi Hemami, Y. Wang, Combinatorica 46 (2026)."}},{"status":"public","PlanS_conform":"1","arxiv":1,"volume":706,"title":"The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy","date_published":"2026-02-01T00:00:00Z","_id":"21160","quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-02-16T09:36:24Z","year":"2026","ddc":["520"],"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"02","intvolume":"       706","file_date_updated":"2026-02-16T09:33:56Z","OA_place":"publisher","day":"01","citation":{"chicago":"Yu, W., A. F. Pala, T. Kupfer, B. T. Gänsicke, D. Koester, D. Belloni, T. L.S. Wong, et al. “The Evolutionary History of Ultra-Compact Accreting Binaries: I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System ZTF J225237.05-051917.4 from HST Spectroscopy.” <i>Astronomy and Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202557568\">https://doi.org/10.1051/0004-6361/202557568</a>.","short":"W. Yu, A.F. Pala, T. Kupfer, B.T. Gänsicke, D. Koester, D. Belloni, T.L.S. Wong, M.R. Schreiber, J.C. van Roestel, A.J. Brown, E.O. Waagen, J.L. González-Carballo, S. Bednarz, K. Bernacki, D. De Martino, E. Fernández Mañanes, R. González Farfán, M.J. Green, P.J. Groot, F.J. Hambsch, C. Knigge, J.L. Martin-Velasco, M. Morales-Aimar, G. Myers, R. Naves Nogues, R. Poggiani, A. Popowicz, G. Ramsay, E. Reina-Lorenz, P. Rodríguez-Gil, J.L. Salto-González, E.M. Sion, D. Steeghs, P. Szkody, O. Toloza, G. Tovmassian, Astronomy and Astrophysics 706 (2026).","ama":"Yu W, Pala AF, Kupfer T, et al. The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. <i>Astronomy and Astrophysics</i>. 2026;706. doi:<a href=\"https://doi.org/10.1051/0004-6361/202557568\">10.1051/0004-6361/202557568</a>","ieee":"W. Yu <i>et al.</i>, “The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy,” <i>Astronomy and Astrophysics</i>, vol. 706. EDP Sciences, 2026.","mla":"Yu, W., et al. “The Evolutionary History of Ultra-Compact Accreting Binaries: I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System ZTF J225237.05-051917.4 from HST Spectroscopy.” <i>Astronomy and Astrophysics</i>, vol. 706, A14, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202557568\">10.1051/0004-6361/202557568</a>.","ista":"Yu W, Pala AF, Kupfer T, Gänsicke BT, Koester D, Belloni D, Wong TLS, Schreiber MR, van Roestel JC, Brown AJ, Waagen EO, González-Carballo JL, Bednarz S, Bernacki K, De Martino D, Fernández Mañanes E, González Farfán R, Green MJ, Groot PJ, Hambsch FJ, Knigge C, Martin-Velasco JL, Morales-Aimar M, Myers G, Naves Nogues R, Poggiani R, Popowicz A, Ramsay G, Reina-Lorenz E, Rodríguez-Gil P, Salto-González JL, Sion EM, Steeghs D, Szkody P, Toloza O, Tovmassian G. 2026. The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and Astrophysics. 706, A14.","apa":"Yu, W., Pala, A. F., Kupfer, T., Gänsicke, B. T., Koester, D., Belloni, D., … Tovmassian, G. (2026). The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. <i>Astronomy and Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202557568\">https://doi.org/10.1051/0004-6361/202557568</a>"},"oa":1,"article_processing_charge":"No","type":"journal_article","department":[{"_id":"IlCa"}],"acknowledgement":"We thank Lars Bildsten for valuable insights and discussions. We acknowledge with thanks the variable star observations from the\r\nAAVSO International Database contributed by observers worldwide and used in this research. We thank the members of the Spanish Observers of Supernovae\r\n(ObSN) group for their valuable photometric contributions. This research was\r\nsupported by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2121 “Quantum Universe”\r\n– 390833306. Co-funded by the European Union (ERC, CompactBINARIES,\r\n101078773). Views and opinions expressed are however those of the author(s)\r\nonly and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority\r\ncan be held responsible for them. DB acknowledges support from the São Paulo\r\nResearch Foundation (FAPESP), Brazil, Process Numbers #2024/03736-2 and\r\n#2025/00817-4. MRS is supported by Fondecyt (grant 1221059). MJG acknowledges support from the European Research Council through ERC Advanced\r\nGrant No. 101054731, from the National Aeronautics and Space Administration under grants 80NSSC24K0436, 80NSSC22K0479, and 80NSSC24K0380,\r\nand from the National Science Foundation under grant AST-2205736. PJG\r\nis supported by NRF SARChI grant 111692. PR-G acknowledges support by\r\nthe Agencia Estatal de Investigación del Ministerio de Ciencia e Innovación\r\n(MCIN/AEI) and the European Regional Development Fund (ERDF) under grant\r\nPID2021–124879NB–I00. DS is supported by the UK Science and Technology Facilities Council (STFC, grant numbers ST/T007184/1, ST/T003103/1,\r\nand ST/T000406/1). OT acknowledges Proyectos Internos USM 2025, PI-LII2025-03. GT was supported by grants IN109723 from the Programa de Apoyo a\r\nProyectos de Investigación e Innovación Tecnológica (PAPIIT). This project has\r\nreceived funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101020057).","author":[{"first_name":"W.","full_name":"Yu, W.","last_name":"Yu"},{"full_name":"Pala, A. F.","last_name":"Pala","first_name":"A. F."},{"first_name":"T.","full_name":"Kupfer, T.","last_name":"Kupfer"},{"last_name":"Gänsicke","full_name":"Gänsicke, B. T.","first_name":"B. T."},{"last_name":"Koester","full_name":"Koester, D.","first_name":"D."},{"first_name":"D.","last_name":"Belloni","full_name":"Belloni, D."},{"full_name":"Wong, T. L.S.","last_name":"Wong","first_name":"T. L.S."},{"first_name":"M. R.","full_name":"Schreiber, M. R.","last_name":"Schreiber"},{"first_name":"Joannes C","id":"4d122fc8-6083-11f0-87a5-97d68b860333","last_name":"van Roestel","full_name":"van Roestel, Joannes C"},{"first_name":"A. J.","last_name":"Brown","full_name":"Brown, A. J."},{"first_name":"E. O.","last_name":"Waagen","full_name":"Waagen, E. O."},{"full_name":"González-Carballo, J. L.","last_name":"González-Carballo","first_name":"J. L."},{"last_name":"Bednarz","full_name":"Bednarz, S.","first_name":"S."},{"first_name":"K.","last_name":"Bernacki","full_name":"Bernacki, K."},{"last_name":"De Martino","full_name":"De Martino, D.","first_name":"D."},{"last_name":"Fernández Mañanes","full_name":"Fernández Mañanes, E.","first_name":"E."},{"first_name":"R.","last_name":"González Farfán","full_name":"González Farfán, R."},{"last_name":"Green","full_name":"Green, M. J.","first_name":"M. J."},{"first_name":"P. J.","last_name":"Groot","full_name":"Groot, P. J."},{"first_name":"F. J.","last_name":"Hambsch","full_name":"Hambsch, F. J."},{"first_name":"C.","last_name":"Knigge","full_name":"Knigge, C."},{"first_name":"J. L.","full_name":"Martin-Velasco, J. L.","last_name":"Martin-Velasco"},{"full_name":"Morales-Aimar, M.","last_name":"Morales-Aimar","first_name":"M."},{"first_name":"G.","full_name":"Myers, G.","last_name":"Myers"},{"first_name":"R.","last_name":"Naves Nogues","full_name":"Naves Nogues, R."},{"full_name":"Poggiani, R.","last_name":"Poggiani","first_name":"R."},{"last_name":"Popowicz","full_name":"Popowicz, A.","first_name":"A."},{"first_name":"G.","full_name":"Ramsay, G.","last_name":"Ramsay"},{"last_name":"Reina-Lorenz","full_name":"Reina-Lorenz, E.","first_name":"E."},{"first_name":"P.","full_name":"Rodríguez-Gil, P.","last_name":"Rodríguez-Gil"},{"last_name":"Salto-González","full_name":"Salto-González, J. L.","first_name":"J. L."},{"full_name":"Sion, E. M.","last_name":"Sion","first_name":"E. M."},{"last_name":"Steeghs","full_name":"Steeghs, D.","first_name":"D."},{"last_name":"Szkody","full_name":"Szkody, P.","first_name":"P."},{"first_name":"O.","last_name":"Toloza","full_name":"Toloza, O."},{"full_name":"Tovmassian, G.","last_name":"Tovmassian","first_name":"G."}],"OA_type":"diamond","external_id":{"arxiv":["2512.04147"]},"article_number":"A14","scopus_import":"1","publication_status":"published","abstract":[{"text":"Context. AM Canum Venaticorum (AM CVn) stars are ultra-compact binary systems composed of a white dwarf primary accreting from a hydrogen-deficient donor. They play a crucial role in astrophysics as potential progenitors of Type Ia supernovae and as laboratories for gravitational wave studies. However, their formation and evolutionary history remain incomplete. Three formation channels have been discussed in the literature: the white dwarf, He-star, and cataclysmic variable channels.\r\n\r\nAims. The chemical composition of the accretor atmosphere reflects the material transferred from the donor. In this work we took the first accurate measurements of the fundamental parameters of the accreting white dwarf in ZTF J225237.05−051917.4, including the abundances of key elements such as carbon, nitrogen, and silicon, by analysing ultraviolet spectra obtained with the Hubble Space Telescope (HST). These measurements provide new insight into the evolutionary history of the system and, together with existing optical observations, establish it as a benchmark to develop our pipeline, paving the way for its application to a larger sample of AM CVn systems.\r\n\r\nMethods. We determined the binary parameters through photometric analysis and constrained the atmospheric parameters of the white dwarf accretor, including its effective temperature, surface gravity, and chemical abundances, by fitting the HST ultraviolet spectrum with synthetic spectral models. We then inferred the system’s formation channel by comparing the results with theoretical evolutionary models.\r\n\r\nResults. According to our measurements, the accretor’s effective temperature (Teff) is 23 300 ± 600 K and the surface gravity (log g) is 8.4 ± 0.3, which imply an accretor mass (MWD) of 0.86 ± 0.16 M⊙. We find a high nitrogen-to-carbon abundance ratio by mass of > 153.\r\n\r\nConclusions. The accretor is significantly hotter than previous estimates based on simplified blackbody fits to the spectral energy distribution, underscoring the importance of detailed spectral modelling for accurately determining system parameters. Our results show that ultraviolet spectroscopy is well suited to constraining the formation channels of AM CVn systems. Of the three proposed formation channels, the He-star channel can be excluded given the high nitrogen-to-carbon ratio. Our results are consistent with both the white dwarf and cataclysmic variable channels.","lang":"eng"}],"publication":"Astronomy and Astrophysics","file":[{"file_id":"21227","creator":"dernst","date_updated":"2026-02-16T09:33:56Z","file_name":"2026_AstronomyAstrophysics_Yu.pdf","success":1,"checksum":"2faec710fd04f927aa43deb57e35c9b2","date_created":"2026-02-16T09:33:56Z","file_size":4020466,"access_level":"open_access","content_type":"application/pdf","relation":"main_file"}],"doi":"10.1051/0004-6361/202557568","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-08T23:02:49Z","publisher":"EDP Sciences","article_type":"original"},{"language":[{"iso":"eng"}],"date_updated":"2026-02-16T09:27:33Z","quality_controlled":"1","_id":"21161","date_published":"2026-01-28T00:00:00Z","month":"01","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","ddc":["570"],"year":"2026","corr_author":"1","PlanS_conform":"1","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"Bio"}],"status":"public","title":"Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster","volume":293,"publication_identifier":{"eissn":["1471-2954"]},"oa_version":"Published Version","pmid":1,"doi":"10.1098/rspb.2025.2471","abstract":[{"lang":"eng","text":"In many species, sex-biased expression is widespread and thought to contribute to sexual dimorphism. While bulk RNA-sequencing has been instrumental in identifying strongly sex-biased genes, it lacks resolution to assess variation across cell-types and tissue compartments. Using single-nucleus expression data from the Fly Cell Atlas, we investigate sex differences in adult Drosophila melanogaster. We find that differences in cell-type composition between the sexes are not a major source of sex-bias, as for the vast majority of genes, the degree of sex-bias is similar regardless of whether sex differences in cell-type composition are controlled for or not. Our analysis confirms a deficit of X-linked male-biased genes in the body’s somatic tissues that is widespread across cell-types. We also find the excess of X-linked female-biased genes to be associated with nervous system cells in the head but with epithelial cells in the body’s somatic tissues, showing that single-nucleus data crucially resolves sex-bias at the cell-type level. We investigate dosage compensation (DC) across 15 tissues and 17 cell-types. We observe that it varies throughout the body. Surprisingly, we observe a lack of DC in a cluster of main cells within the male accessory glands. This result highlights the importance of understanding context-dependent DC."}],"publication":"Proceedings of the Royal Society B Biological Sciences","file":[{"file_size":2230841,"date_created":"2026-02-16T09:26:02Z","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"dernst","file_id":"21226","date_updated":"2026-02-16T09:26:02Z","checksum":"d76afebca0a6f112df0146ae2d929f36","file_name":"2026_RoyalSocPubProceedingsB_Barata.pdf","success":1}],"publication_status":"published","article_type":"original","publisher":"Royal Society of London","date_created":"2026-02-08T23:02:49Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"citation":{"chicago":"Castro Barbosa Rodrigues Barata, Carolina de, and Beatriz Vicoso. “Single-Nucleus Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.” <i>Proceedings of the Royal Society B Biological Sciences</i>. Royal Society of London, 2026. <a href=\"https://doi.org/10.1098/rspb.2025.2471\">https://doi.org/10.1098/rspb.2025.2471</a>.","ama":"de Castro Barbosa Rodrigues Barata C, Vicoso B. Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. <i>Proceedings of the Royal Society B Biological Sciences</i>. 2026;293(2063). doi:<a href=\"https://doi.org/10.1098/rspb.2025.2471\">10.1098/rspb.2025.2471</a>","short":"C. de Castro Barbosa Rodrigues Barata, B. Vicoso, Proceedings of the Royal Society B Biological Sciences 293 (2026).","ieee":"C. de Castro Barbosa Rodrigues Barata and B. Vicoso, “Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster,” <i>Proceedings of the Royal Society B Biological Sciences</i>, vol. 293, no. 2063. Royal Society of London, 2026.","ista":"de Castro Barbosa Rodrigues Barata C, Vicoso B. 2026. Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings of the Royal Society B Biological Sciences. 293(2063), 20252471.","apa":"de Castro Barbosa Rodrigues Barata, C., &#38; Vicoso, B. (2026). Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. <i>Proceedings of the Royal Society B Biological Sciences</i>. Royal Society of London. <a href=\"https://doi.org/10.1098/rspb.2025.2471\">https://doi.org/10.1098/rspb.2025.2471</a>","mla":"de Castro Barbosa Rodrigues Barata, Carolina, and Beatriz Vicoso. “Single-Nucleus Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.” <i>Proceedings of the Royal Society B Biological Sciences</i>, vol. 293, no. 2063, 20252471, Royal Society of London, 2026, doi:<a href=\"https://doi.org/10.1098/rspb.2025.2471\">10.1098/rspb.2025.2471</a>."},"day":"28","OA_place":"publisher","file_date_updated":"2026-02-16T09:26:02Z","intvolume":"       293","scopus_import":"1","article_number":"20252471","external_id":{"pmid":["41592777"]},"OA_type":"hybrid","author":[{"orcid":"0000-0003-1945-2245","first_name":"Carolina","id":"20565186-803f-11ed-ab7e-96a4ff7694ef","full_name":"De Castro Barbosa Rodrigues Barata, Carolina","last_name":"De Castro Barbosa Rodrigues Barata"},{"full_name":"Vicoso, Beatriz","last_name":"Vicoso","orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz"}],"project":[{"grant_number":"ESP 6331524","_id":"90ef7108-16d5-11f0-9cad-e6e116913473","name":"Does genetic drift set a limit on the adaptive evolution of sex-biased expression?"}],"department":[{"_id":"BeVi"}],"issue":"2063","acknowledgement":"This work was partly funded by an Austrian Science Foundation FWF ESPRIT fellowship (10.55776/ESP6331524) to C.B. We would like to thank the Vicoso group for their invaluable input and discussions throughout this work. We thank Filip Ruzicka for his insightful comments on the manuscript. All computational resources were provided by the Scientific Computing Unit at ISTA. This research was also supported through resources provided by the Imaging & Optics Facility (IOF) at ISTA."},{"ec_funded":1,"department":[{"_id":"CaMu"}],"acknowledgement":"Part of this material is based upon work supported by the NSF National Center for Atmospheric Research, which is a major facility sponsored by the National Science Foundation under Cooperative Agreement No. 1852977. Casallas was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. E. D. Freitas thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 313210/2022–5). Silva gratefully acknowledges the financial support from the National Council for Scientific and Technological Development (CNPq), process number 140512/2021–7. P. Lichtig was supported by base funding from the National Commission for Atomic Energy (CNEA, Arg.) and by NSF NCAR. R.Y. Ynoue thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 406728/2022–4). M. A. Franco thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 407752/2023–4). G. M. Pereira thanks the support by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP; Process numbers 2018/07848–9, 2016/18438–0, and 2019/01316–80) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES; Process number 88887.103225/2025–00). M.F. Andrade thanks the support by FAPESP (Process number 2016/18438–0) and CNPQ (Klimapolis INCT).","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"author":[{"full_name":"Ibarra-Espinosa, Sergio","last_name":"Ibarra-Espinosa","first_name":"Sergio"},{"last_name":"Dias de Freitas","full_name":"Dias de Freitas, Edmilson","first_name":"Edmilson"},{"first_name":"Benjamin","full_name":"Gaubert, Benjamin","last_name":"Gaubert"},{"first_name":"Pablo","full_name":"Lichtig, Pablo","last_name":"Lichtig"},{"full_name":"Ropkins, Karl","last_name":"Ropkins","first_name":"Karl"},{"first_name":"Iara","last_name":"da Silva","full_name":"da Silva, Iara"},{"full_name":"Martins Pereira, Guilherme","last_name":"Martins Pereira","first_name":"Guilherme"},{"last_name":"Schuch","full_name":"Schuch, Daniel","first_name":"Daniel"},{"full_name":"Nascimento, Janaina","last_name":"Nascimento","first_name":"Janaina"},{"first_name":"Leonardo","last_name":"Hoinaski","full_name":"Hoinaski, Leonardo"},{"full_name":"Martins, Leila Droprinchinski","last_name":"Martins","first_name":"Leila Droprinchinski"},{"last_name":"Gavidia-Calderón","full_name":"Gavidia-Calderón, Mario","first_name":"Mario"},{"last_name":"Vara-Vela","full_name":"Vara-Vela, Angel","first_name":"Angel"},{"full_name":"Toledo de Almeida Albuquerque, Taciana","last_name":"Toledo de Almeida Albuquerque","first_name":"Taciana"},{"full_name":"Ynoue, Rita Yuri","last_name":"Ynoue","first_name":"Rita Yuri"},{"first_name":"Sebastian","last_name":"Diez","full_name":"Diez, Sebastian"},{"first_name":"Zamir","full_name":"Mera, Zamir","last_name":"Mera"},{"last_name":"Casallas Garcia","full_name":"Casallas Garcia, Alejandro","orcid":"0000-0002-1988-5035","first_name":"Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a"},{"full_name":"Vallejo, Fidel","last_name":"Vallejo","first_name":"Fidel"},{"first_name":"Valeria","last_name":"Diaz","full_name":"Diaz, Valeria"},{"full_name":"Pedruzzi, Rizzieri","last_name":"Pedruzzi","first_name":"Rizzieri"},{"last_name":"Abrutzky","full_name":"Abrutzky, Rosana","first_name":"Rosana"},{"first_name":"Marco A.","full_name":"Franco, Marco A.","last_name":"Franco"},{"first_name":"Nicolas","full_name":"Huneeus, Nicolas","last_name":"Huneeus"},{"last_name":"Jorquera","full_name":"Jorquera, Hector","first_name":"Hector"},{"last_name":"Belalcázar-Cerón","full_name":"Belalcázar-Cerón, Luis Carlos","first_name":"Luis Carlos"},{"last_name":"Rojas","full_name":"Rojas, Néstor Y.","first_name":"Néstor Y."},{"first_name":"Maria","full_name":"de Fatima Andrade, Maria","last_name":"de Fatima Andrade"},{"full_name":"Emmons, Louisa","last_name":"Emmons","first_name":"Louisa"},{"full_name":"Brasseur, Guy","last_name":"Brasseur","first_name":"Guy"}],"external_id":{"pmid":["41636708"]},"scopus_import":"1","article_number":"5c08400","day":"04","citation":{"ieee":"S. Ibarra-Espinosa <i>et al.</i>, “A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality,” <i>Environmental Science &#38;amp; Technology</i>. American Chemical Society, 2026.","mla":"Ibarra-Espinosa, Sergio, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” <i>Environmental Science &#38;amp; Technology</i>, 5c08400, American Chemical Society, 2026, doi:<a href=\"https://doi.org/10.1021/acs.est.5c08400\">10.1021/acs.est.5c08400</a>.","ista":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, Lichtig P, Ropkins K, da Silva I, Martins Pereira G, Schuch D, Nascimento J, Hoinaski L, Martins LD, Gavidia-Calderón M, Vara-Vela A, Toledo de Almeida Albuquerque T, Ynoue RY, Diez S, Mera Z, Casallas Garcia A, Vallejo F, Diaz V, Pedruzzi R, Abrutzky R, Franco MA, Huneeus N, Jorquera H, Belalcázar-Cerón LC, Rojas NY, de Fatima Andrade M, Emmons L, Brasseur G. 2026. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &#38;amp; Technology., 5c08400.","apa":"Ibarra-Espinosa, S., Dias de Freitas, E., Gaubert, B., Lichtig, P., Ropkins, K., da Silva, I., … Brasseur, G. (2026). A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. <i>Environmental Science &#38;amp; Technology</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.est.5c08400\">https://doi.org/10.1021/acs.est.5c08400</a>","chicago":"Ibarra-Espinosa, Sergio, Edmilson Dias de Freitas, Benjamin Gaubert, Pablo Lichtig, Karl Ropkins, Iara da Silva, Guilherme Martins Pereira, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” <i>Environmental Science &#38;amp; Technology</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.est.5c08400\">https://doi.org/10.1021/acs.est.5c08400</a>.","short":"S. Ibarra-Espinosa, E. Dias de Freitas, B. Gaubert, P. Lichtig, K. Ropkins, I. da Silva, G. Martins Pereira, D. Schuch, J. Nascimento, L. Hoinaski, L.D. Martins, M. Gavidia-Calderón, A. Vara-Vela, T. Toledo de Almeida Albuquerque, R.Y. Ynoue, S. Diez, Z. Mera, A. Casallas Garcia, F. Vallejo, V. Diaz, R. Pedruzzi, R. Abrutzky, M.A. Franco, N. Huneeus, H. Jorquera, L.C. Belalcázar-Cerón, N.Y. Rojas, M. de Fatima Andrade, L. Emmons, G. Brasseur, Environmental Science &#38;amp; Technology (2026).","ama":"Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, et al. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. <i>Environmental Science &#38;amp; Technology</i>. 2026. doi:<a href=\"https://doi.org/10.1021/acs.est.5c08400\">10.1021/acs.est.5c08400</a>"},"article_processing_charge":"No","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-09T06:54:10Z","article_type":"original","publisher":"American Chemical Society","publication_status":"epub_ahead","abstract":[{"text":"Global emission inventories often fail to capture the complexities of vehicular pollution in regions with unique fuel mixes, such as Brazil’s extensive biofuel use, leading to significant uncertainties in atmospheric modeling. This study presents a century-long (1960–2100) bottom-up vehicular emission inventory for Brazil, leveraging locally derived emission factors. Our estimates reveal substantial discrepancies in magnitude, timing, and speciation of non-CO2 pollutants (CO, NMHC, PM2.5) compared to leading global inventories (EDGAR, CEDS, CAMS), highlighting critical inaccuracies in widely used data sets. More critically, future projections under Shared Socioeconomic Pathways (SSPs) uncover a novel positive feedback mechanism: rising temperatures significantly enhance vehicular evaporative nonmethane hydrocarbon (NMHC) emissions. This temperature-dependent increase and subsequent NMHC oxidation to CO2 suggest an overlooked pathway that could amplify climate warming and air pollution globally, particularly after a breakpoint around 2050 (p < 0.05). While historical emissions peaked in the 1990s–2000s, nonexhaust PM becomes increasingly important. Air quality simulations using our inventory in the MUSICA model show good regional PM2.5 agreement but highlight challenges in resolving local primary pollutant peaks. This comprehensive inventory provides crucial data for Brazil and uncovers globally relevant climate–chemistry interactions, urging a re-evaluation of regional specificities in global emission assessments.","lang":"eng"}],"publication":"Environmental Science &amp; Technology","doi":"10.1021/acs.est.5c08400","publication_identifier":{"issn":["0013-936X"],"eissn":["1520-5851"]},"pmid":1,"oa_version":"None","title":"A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality","status":"public","year":"2026","ddc":["550"],"has_accepted_license":"1","month":"02","date_published":"2026-02-04T00:00:00Z","_id":"21164","quality_controlled":"1","language":[{"iso":"eng"}],"date_updated":"2026-02-16T10:33:07Z"},{"citation":{"mla":"Modic, Kimberly A. <i>Research Data for “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>.","ista":"Modic KA. 2026. Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>.","apa":"Modic, K. A. (2026). Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">https://doi.org/10.15479/AT-ISTA-21174</a>","ieee":"K. A. Modic, “Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026.","ama":"Modic KA. Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21174\">10.15479/AT-ISTA-21174</a>","short":"K.A. Modic, (2026).","chicago":"Modic, Kimberly A. “Research Data for ‘Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21174\">https://doi.org/10.15479/AT-ISTA-21174</a>."},"type":"research_data","article_processing_charge":"Yes","oa":1,"day":"19","keyword":["transverse magnetic susceptibility","magnetotropic","superconductivity","magnetic fluctuations"],"OA_place":"repository","file_date_updated":"2026-02-19T07:39:07Z","OA_type":"free access","author":[{"full_name":"Modic, Kimberly A","last_name":"Modic","orcid":"0000-0001-9760-3147","first_name":"Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425"}],"project":[{"grant_number":"101078696","_id":"bd968c70-d553-11ed-ba76-cde40b0aba64","name":"Gaining leverage with spin liquids and superconductors"}],"acknowledgement":"Thanks to Salvatore Bagiante, Evgeniia Volobueva, Lubuna Shafeek, Ali Bangura and Zoltan Kollo.","department":[{"_id":"KiMo"}],"oa_version":"Published Version","abstract":[{"text":"UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby the zero-resistance state reappears above 40 tesla after being suppressed with a field of around 10 tesla. One potential pairing mechanism, invoked in the related re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of a ferromagnetic order parameter. However, the requisite ferromagnetic order - present in both UCoGe and URhGe - is absent in UTe2, and magnetization measurements show no sign of strong fluctuations. Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle planes. This quantity is sensitive to the magnetic susceptibility in a direction transverse to the applied magnetic field - a quantity that is not accessed in conventional magnetization measurements. We observe a very large decrease in the magnetotropic susceptibility over a broad range of field orientations, indicating a large increase in the transverse magnetic susceptibility. The three superconducting phases of UTe2, including the high-field re-entrant phase, surround this region of enhanced susceptibility in the field-angle phase diagram. The strongest transverse susceptibility is found near the critical end point of the high-field metamagnetic transition, suggesting that quantum critical fluctuations of a field-induced magnetic order parameter may be responsible for the large transverse susceptibility, and may provide a pairing mechanism for field-induced superconductivity in UTe2.","lang":"eng"}],"file":[{"access_level":"open_access","relation":"main_file","content_type":"text/plain","date_created":"2026-02-19T07:38:15Z","file_size":1347,"date_updated":"2026-02-19T07:38:15Z","file_id":"21332","creator":"kmodic","success":1,"file_name":"README.txt","checksum":"53157d908fba663275c2b8dc6ee84fdb"},{"date_updated":"2026-02-19T07:39:03Z","file_id":"21333","creator":"kmodic","success":1,"file_name":"processed_data_bc_plane_Fig2d.zip","checksum":"b2c8ca5620ee9c181a42082068d3d73c","access_level":"open_access","relation":"main_file","content_type":"application/zip","date_created":"2026-02-19T07:39:03Z","file_size":534853},{"creator":"kmodic","file_id":"21334","date_updated":"2026-02-19T07:39:07Z","checksum":"976bf113da4b1133313f0b292e71289f","file_name":"processed_data_ac_plane_Fig2c.zip","success":1,"file_size":427144,"date_created":"2026-02-19T07:39:07Z","relation":"main_file","content_type":"application/zip","access_level":"open_access"}],"doi":"10.15479/AT-ISTA-21174","date_created":"2026-02-09T12:04:20Z","publisher":"Institute of Science and Technology Austria","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","contributor":[{"first_name":"Valeska","id":"467ed36b-dc96-11ea-b7c8-b043a380b282","orcid":"0000-0002-8806-5719","last_name":"Zambra","contributor_type":"project_member"}],"corr_author":"1","acknowledged_ssus":[{"_id":"NanoFab"}],"status":"public","title":"Research data for \"Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2\"","date_updated":"2026-05-11T06:35:59Z","_id":"21174","date_published":"2026-02-19T00:00:00Z","month":"02","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","related_material":{"record":[{"id":"21845","relation":"used_in_publication","status":"public"}],"link":[{"relation":"preprint","url":"https://arxiv.org/pdf/2506.08984"}]},"year":"2026","ddc":["530"]},{"publication_identifier":{"issn":["2663-337X"]},"oa_version":"Published Version","degree_awarded":"PhD","doi":"10.15479/AT-ISTA-21198","abstract":[{"text":"In recent years there has been a massive increase in the amount of data generated in a\r\ndecentralized manner. Ever more powerful edge devices, such as smartphones, have become\r\nubiquitous in most societies on earth. Through text typed, photos taken and apps used,\r\nthese devices, which we refer to as clients, generate enormous amounts of high quality and\r\ncomplex data. Moreover, the nature of these devices means the data they generate is often\r\nsensitive and privacy concerns prevent it being gathered and stored in a central location. This\r\npresents a challenge to the modern machine learning paradigm that requires central access\r\nto large amounts of data. Federated learning (FL) has emerged as one of the answers to\r\nthis problem. Rather than bringing the data to the model, FL sends the model to the data.\r\nModel training takes place on device, with periodically synchronized updates, allowing data to\r\nremain locally stored. While this approach offers significant privacy advantages it comes with\r\nits own set of unique challenges. These include: data heterogeneity, the notion that different\r\ndevices generate data in distinct ways which can negatively impact training dynamics; systems\r\nheterogeneity, meaning that different devices may have differing hardware specifications; high\r\ncommunication costs, which are induced by the repeated transferring of models over the\r\nnetwork and low device computational power, which limits the use of larger models on device.\r\nIn this thesis we present a range of methods for federated learning. We focus primarily on\r\nthe challenge of data heterogeneity, though the methods presented are designed to be well\r\nadapted to the other challenges of a federated setting, such as the constraints of limited\r\ncompute and communication overhead. We first present a method for explicitly modeling client\r\ndata heterogeneity. The approach formulates clients as samples from a certain probability\r\ndistribution and infers the parameters of this distribution from the available training clients.\r\nThis learned distribution then represents the heterogeneity present among the clients and can\r\nbe sampled from in order to create new simulated clients that are similar to the real clients we\r\nhave observed so far. Following this we present two methods for directly dealing with data\r\nheterogeneity through personalization. Highly heterogeneous client data distributions can mean\r\nthat learning a single global model becomes suboptimal, and some form of personalization of\r\nmodels to each individual client is required. Our approaches are based around hypernetworks,\r\nwhich we use to generate personalized model parameters without the need for additional\r\ntraining or finetuning. In the first approach we focus on generating full parameterizations of\r\nclient models using learned embeddings of client data and labels, with a hypernetwork located\r\non the central server. In the second approach we address the more challenging scenario where\r\nwe want to generate a personalized model for a client without any label information. The\r\nhypernetwork is trained to generate a low dimensional representation of a client’s personalized\r\nmodel parameters, allowing it to be transferred to and run on the client devices. In our final\r\npresented method, we change our focus and rather than aim to directly address the challenge\r\nof data heterogeneity, we instead ensure we are unaffected by it. This is done in the context\r\nof k-means clustering and we present a method for federated clustering with a focus on added\r\nprivacy guarantees.","lang":"eng"}],"file":[{"file_id":"21298","creator":"jscott","date_updated":"2026-02-17T11:46:22Z","file_name":"2026_Scott_Jonathan_Thesis_Source.zip","checksum":"121c1d968bd86f3630aa7e81d5bbbcb0","date_created":"2026-02-17T11:46:22Z","file_size":272379252,"access_level":"closed","content_type":"application/zip","relation":"source_file"},{"checksum":"6e3e08ba474bbee8511cc8a839ab2077","success":1,"file_name":"2026_Jonathan_Scott_Thesis.pdf","creator":"jscott","file_id":"21366","date_updated":"2026-02-27T10:25:41Z","file_size":15220298,"date_created":"2026-02-27T10:25:41Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"publication_status":"published","publisher":"Institute of Science and Technology Austria","date_created":"2026-02-09T14:59:53Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","article_processing_charge":"No","type":"dissertation","oa":1,"citation":{"ieee":"J. A. Scott, “Data heterogeneity and personalization in federated learning,” Institute of Science and Technology Austria, 2026.","mla":"Scott, Jonathan A. <i>Data Heterogeneity and Personalization in Federated Learning</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>.","apa":"Scott, J. A. (2026). <i>Data heterogeneity and personalization in federated learning</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>","ista":"Scott JA. 2026. Data heterogeneity and personalization in federated learning. Institute of Science and Technology Austria.","chicago":"Scott, Jonathan A. “Data Heterogeneity and Personalization in Federated Learning.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>.","short":"J.A. Scott, Data Heterogeneity and Personalization in Federated Learning, Institute of Science and Technology Austria, 2026.","ama":"Scott JA. Data heterogeneity and personalization in federated learning. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>"},"day":"09","file_date_updated":"2026-02-27T10:25:41Z","OA_place":"publisher","author":[{"full_name":"Scott, Jonathan A","last_name":"Scott","first_name":"Jonathan A","id":"e499926b-f6e0-11ea-865d-9c63db0031e8"}],"acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF)\r\n[10.55776/COE12]. Furthermore, the candidate acknowledges the support from the Scientific\r\nService Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).","department":[{"_id":"GradSch"},{"_id":"ChLa"}],"language":[{"iso":"eng"}],"date_updated":"2026-04-07T11:46:11Z","alternative_title":["ISTA Thesis"],"_id":"21198","date_published":"2026-02-09T00:00:00Z","related_material":{"record":[{"id":"20819","relation":"part_of_dissertation","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"17411"},{"status":"public","relation":"part_of_dissertation","id":"18120"},{"relation":"part_of_dissertation","id":"21207","status":"public"}]},"month":"02","has_accepted_license":"1","ddc":["005"],"year":"2026","supervisor":[{"id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph","orcid":"0000-0001-8622-7887","last_name":"Lampert","full_name":"Lampert, Christoph"}],"corr_author":"1","page":"158","acknowledged_ssus":[{"_id":"ScienComp"}],"status":"public","title":"Data heterogeneity and personalization in federated learning"},{"status":"public","day":"16","OA_place":"repository","citation":{"ama":"Jiang Y, Ahn R, Huang A, et al. Critical role of cell competition in gliomagenesis. <i>bioRxiv</i>. 2026. doi:<a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>","short":"Y. Jiang, R. Ahn, A. Huang, P.P. Gonzalez, J. Kim, G. Zhang, Z. Liu, Z. He, L. Dudley, K.S. Patel, G.A. Dzhivhuho, S. Crowl, P. Przanowski, L.Q. Camacho, S. Hao, J. Zeng, S. Hippenmeyer, M. Fallahi-Sichani, K.A. Janes, K.M. Naegle, M.-L. Hammarskjold, S.A. Goldman, H.I. Kornblum, M. Yao, F. White, H. Zong, BioRxiv (2026).","chicago":"Jiang, Ying, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun Kim, Guoxin Zhang, Zihao Liu, et al. “Critical Role of Cell Competition in Gliomagenesis.” <i>BioRxiv</i>, 2026. <a href=\"https://doi.org/10.64898/2026.01.15.699808\">https://doi.org/10.64898/2026.01.15.699808</a>.","apa":"Jiang, Y., Ahn, R., Huang, A., Gonzalez, P. P., Kim, J., Zhang, G., … Zong, H. (2026). Critical role of cell competition in gliomagenesis. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.01.15.699808\">https://doi.org/10.64898/2026.01.15.699808</a>","ista":"Jiang Y, Ahn R, Huang A, Gonzalez PP, Kim J, Zhang G, Liu Z, He Z, Dudley L, Patel KS, Dzhivhuho GA, Crowl S, Przanowski P, Camacho LQ, Hao S, Zeng J, Hippenmeyer S, Fallahi-Sichani M, Janes KA, Naegle KM, Hammarskjold M-L, Goldman SA, Kornblum HI, Yao M, White F, Zong H. 2026. Critical role of cell competition in gliomagenesis. bioRxiv, <a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>.","mla":"Jiang, Ying, et al. “Critical Role of Cell Competition in Gliomagenesis.” <i>BioRxiv</i>, 2026, doi:<a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>.","ieee":"Y. Jiang <i>et al.</i>, “Critical role of cell competition in gliomagenesis,” <i>bioRxiv</i>. 2026."},"type":"preprint","article_processing_charge":"No","oa":1,"department":[{"_id":"SiHi"}],"acknowledgement":"We thank Dr. Wenjie Liu for providing critical feedback on the manuscript. We also thank Dr.\r\nPat Pramoonjago at the Biorepository and Tissue Research Facility, and Hope Davis at the\r\nvivarium for their assistance on the project. These Core Facilities are supported by UVA Cancer\r\nCenter grant #P30-CA044579. We are grateful to Dr. Jonathan A. Epstein for providing the\r\nNf1GRD/+ mouse strain (https://pubmed.ncbi.nlm.nih.gov/26460546/). This work was partly\r\nsupported by the National Institute of Neurological Diseases and Stroke R21 NS125479-01A1\r\n(H.Z.), American Cancer Society Institutional Research Grant to the University of Virginia\r\n(Y.J.), the National Natural Science Foundation of China #82072787 (M.Y.), the National\r\nCancer Institute U54 CA238114 (F.W.), U01 CA284193 (K.M.N.), and U54 CA274499 (K.A.J.,\r\nM.F-S.), the National institute of General Medical Sciences R35 GM133404 (M.F-S.), the Dr.\r\nMiriam and Sheldon G. Adelson Medical Research Foundation (H.I.K., S.A.G.), the National\r\nCenter for Advancing Translational Sciences KL2TR001882 (K.S.P.), Tower Cancer Career Development Grant (K.S.P.), McKnight Neurobiology of Brain Disorders Grant (K.S.P.). The\r\ncontent is solely the responsibility of the authors and does not necessarily represent the official\r\nviews of the National Institutes of Health. Illustrations in this manuscript were created with\r\nBioRender (BioRender.com).","OA_type":"green","author":[{"first_name":"Ying","full_name":"Jiang, Ying","last_name":"Jiang"},{"last_name":"Ahn","full_name":"Ahn, Ryuhjin","first_name":"Ryuhjin"},{"full_name":"Huang, Arthur","last_name":"Huang","first_name":"Arthur"},{"last_name":"Gonzalez","full_name":"Gonzalez, Phillippe P.","first_name":"Phillippe P."},{"full_name":"Kim, Jungeun","last_name":"Kim","first_name":"Jungeun"},{"full_name":"Zhang, Guoxin","last_name":"Zhang","first_name":"Guoxin"},{"last_name":"Liu","full_name":"Liu, Zihao","first_name":"Zihao"},{"first_name":"Zhenqiang","full_name":"He, Zhenqiang","last_name":"He"},{"last_name":"Dudley","full_name":"Dudley, Lindsey","first_name":"Lindsey"},{"last_name":"Patel","full_name":"Patel, Kunal S.","first_name":"Kunal S."},{"first_name":"Godfrey A.","last_name":"Dzhivhuho","full_name":"Dzhivhuho, Godfrey A."},{"first_name":"Sam","full_name":"Crowl, Sam","last_name":"Crowl"},{"first_name":"Piotr","last_name":"Przanowski","full_name":"Przanowski, Piotr"},{"full_name":"Camacho, Luisa Quesada","last_name":"Camacho","first_name":"Luisa Quesada"},{"first_name":"Sijie","last_name":"Hao","full_name":"Hao, Sijie"},{"last_name":"Zeng","full_name":"Zeng, Jianhao","first_name":"Jianhao"},{"id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","full_name":"Hippenmeyer, Simon"},{"last_name":"Fallahi-Sichani","full_name":"Fallahi-Sichani, Mohammad","first_name":"Mohammad"},{"first_name":"Kevin A.","last_name":"Janes","full_name":"Janes, Kevin A."},{"first_name":"Kristen M.","full_name":"Naegle, Kristen M.","last_name":"Naegle"},{"full_name":"Hammarskjold, Marie-Louise","last_name":"Hammarskjold","first_name":"Marie-Louise"},{"first_name":"Steven A.","last_name":"Goldman","full_name":"Goldman, Steven A."},{"full_name":"Kornblum, Harley I.","last_name":"Kornblum","first_name":"Harley I."},{"first_name":"Maojin","last_name":"Yao","full_name":"Yao, Maojin"},{"full_name":"White, Forest","last_name":"White","first_name":"Forest"},{"last_name":"Zong","full_name":"Zong, Hui","first_name":"Hui"}],"title":"Critical role of cell competition in gliomagenesis","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","publication":"bioRxiv","_id":"21212","main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.01.15.699808"}],"abstract":[{"text":"Malignant glioma is incurable. Using a mouse genetic mosaic system to generate sporadic Trp53,Nf1-null OPCs, we previously identified oligodendrocyte precursor cell (OPC) as a cell-of-origin of glioma. Here, we report that pre-malignant Trp53,Nf1-null OPCs outcompete wildtype counterparts during their expansion. Blocking competition by mutating/strengthening wildtype OPCs impeded both pre-malignant progression and malignant expansion of glioma.\r\n\r\n“In-tissue” phosphoproteomic profiling revealed an enrichment of phosphopeptides related to RNA splicing and protein translation at the peak of cell competition, suggesting that competitiveness may stem from unique protein species. Among candidates was mTORC1, whose pharmacological inhibition or genetic disruption resulted in a loss of competitiveness in our mouse model. Finally, analysis of patient biopsies and interrogating the role of individual gliomagenic mutations in OPC competition supported its relevance in human gliomas. Together, these findings identified the driving role of competitive interactions among OPCs in gliomagenesis, and suggest unconventional therapeutic strategies to target this process.","lang":"eng"}],"publication_status":"published","date_published":"2026-01-16T00:00:00Z","doi":"10.64898/2026.01.15.699808","oa_version":"Preprint","language":[{"iso":"eng"}],"date_updated":"2026-02-16T10:12:42Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","ddc":["570"],"month":"01","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"date_created":"2026-02-10T12:55:55Z","has_accepted_license":"1"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publisher":"Wiley","date_created":"2026-02-12T10:13:02Z","doi":"10.1002/qj.70131","publication":"Quarterly Journal of the Royal Meteorological Society","abstract":[{"lang":"eng","text":"This study investigates the mechanisms driving clustered convection and the breakdown of the Intertropical Convergence Zone (ITCZ) over the Western Pacific Warm Pool using high‐resolution cloud‐resolving simulations and machine‐learning sensitivity experiments. Results show that ITCZ breakdown episodes, marked by spatially homogeneous convection and weakened meridional moisture gradients, are triggered primarily by anomalous moisture advection linked to the equatorial Rossby‐wave activity. While large‐scale moisture advection regulates the background convective state strongly, it is the surface and low‐level meridional winds that dominate transitions between clustered and random convection. Simulations demonstrate that moisture alone can sustain convective clustering, but breakdown episodes are more persistent and widespread when coupled with southerly meridional advection. These findings confirm that wave‐driven advection acts as a regulatory mechanism, periodically disrupting convective clustering and reshaping the meridional moisture gradient. This modulation of organization by wave‐induced breakdown events is critical for understanding tropical convection variability and its implications for the climate system."}],"publication_status":"epub_ahead","oa_version":"Published Version","publication_identifier":{"issn":["0035-9009"],"eissn":["1477-870X"]},"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"call_identifier":"H2020","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","_id":"629205d8-2b32-11ec-9570-e1356ff73576","grant_number":"805041"}],"department":[{"_id":"CaMu"}],"acknowledgement":"This article is based on chapter 5 of the PhD thesis of A. Casallas. The authors thank Graziano Giuliani for discussions on the boundary-condition experiments. A. Casallas was supported by a PhD fellowship awarded by the Abdus Salam International Centre for Theoretical Physics. A. Casallas also acknowledges support by the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 101034413. C. Muller acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). The authors gratefully acknowledge Daniel Hernández-Deckers, Lokahith Agasthya, Chris Holloway, and Paolina Cerlini for their valuable feedback and insightful discussions. They are especially thankful to Bety Pechacova for suggesting the use of SHAP to complement their analysis. They also thank the two anonymous reviewers for their constructive comments, which improved the quality and clarity of the article significantly. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","ec_funded":1,"article_number":"e70131","scopus_import":"1","OA_type":"hybrid","author":[{"first_name":"Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","orcid":"0000-0002-1988-5035","last_name":"Casallas Garcia","full_name":"Casallas Garcia, Alejandro"},{"first_name":"Adrian","last_name":"Mark Tompkins","full_name":"Mark Tompkins, Adrian"},{"id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","first_name":"Caroline J","orcid":"0000-0001-5836-5350","last_name":"Muller","full_name":"Muller, Caroline J"}],"day":"12","OA_place":"publisher","article_processing_charge":"Yes (via OA deal)","type":"journal_article","oa":1,"citation":{"chicago":"Casallas Garcia, Alejandro, Adrian Mark Tompkins, and Caroline J Muller. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>.","short":"A. Casallas Garcia, A. Mark Tompkins, C.J. Muller, Quarterly Journal of the Royal Meteorological Society (2026).","ama":"Casallas Garcia A, Mark Tompkins A, Muller CJ. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. 2026. doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>","ieee":"A. Casallas Garcia, A. Mark Tompkins, and C. J. Muller, “Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events,” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026.","mla":"Casallas Garcia, Alejandro, et al. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>, e70131, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>.","apa":"Casallas Garcia, A., Mark Tompkins, A., &#38; Muller, C. J. (2026). Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>","ista":"Casallas Garcia A, Mark Tompkins A, Muller CJ. 2026. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society., e70131."},"year":"2026","ddc":["550"],"month":"02","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/qj.70131"}],"_id":"21217","date_published":"2026-02-12T00:00:00Z","date_updated":"2026-02-16T10:19:52Z","language":[{"iso":"eng"}],"quality_controlled":"1","license":"https://creativecommons.org/licenses/by-nc/4.0/","title":"Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events","status":"public","corr_author":"1"},{"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2410.01715"}],"_id":"21230","date_published":"2026-01-01T00:00:00Z","language":[{"iso":"eng"}],"date_updated":"2026-02-17T11:05:20Z","editor":[{"last_name":"Mandel","full_name":"Mandel, Ilya","first_name":"Ilya"}],"quality_controlled":"1","year":"2026","month":"01","status":"public","arxiv":1,"page":"133-153","title":"Asteroseismology","volume":2,"doi":"10.1016/b978-0-443-21439-4.00036-5","publication":"Encyclopedia of Astrophysics","abstract":[{"text":"Asteroseismology is the study of the interior physics and structure of stars using their pulsations. It is applicable to stars across the Hertzsprung–Russell (HR) diagram and a powerful technique not only to measure masses, radii, and ages but also directly constrain interior rotation, chemical mixing, and magnetism. This is because a star's self-excited pulsation modes are sensitive to its structure. Asteroseismology generally requires long-duration and high-precision time-series data. The method of forward asteroseismic modeling, which is the statistical comparison of observed pulsation mode frequencies to theoretically predicted pulsation frequencies calculated from a grid of models, provides precise constraints for calibrating various transport phenomena. In this introduction to asteroseismology, we provide an overview of its principles, and the typical data sets and methodologies used to constrain stellar interiors. Finally, we present key highlights of asteroseismic results from across the HR diagram, and conclude with ongoing challenges and future prospects for this ever-expanding field within stellar astrophysics.","lang":"eng"}],"publication_status":"published","publication_identifier":{"isbn":["9780443214400"]},"oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Elsevier","date_created":"2026-02-16T10:43:01Z","day":"01","OA_place":"repository","intvolume":"         2","article_processing_charge":"No","type":"book_chapter","oa":1,"citation":{"chicago":"Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” In <i>Encyclopedia of Astrophysics</i>, edited by Ilya Mandel, 2:133–53. Elsevier, 2026. <a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">https://doi.org/10.1016/b978-0-443-21439-4.00036-5</a>.","ama":"Bowman DM, Bugnet LA. Asteroseismology. In: Mandel I, ed. <i>Encyclopedia of Astrophysics</i>. Vol 2. Elsevier; 2026:133-153. doi:<a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">10.1016/b978-0-443-21439-4.00036-5</a>","short":"D.M. Bowman, L.A. Bugnet, in:, I. Mandel (Ed.), Encyclopedia of Astrophysics, Elsevier, 2026, pp. 133–153.","ieee":"D. M. Bowman and L. A. Bugnet, “Asteroseismology,” in <i>Encyclopedia of Astrophysics</i>, vol. 2, I. Mandel, Ed. Elsevier, 2026, pp. 133–153.","mla":"Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” <i>Encyclopedia of Astrophysics</i>, edited by Ilya Mandel, vol. 2, Elsevier, 2026, pp. 133–53, doi:<a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">10.1016/b978-0-443-21439-4.00036-5</a>.","ista":"Bowman DM, Bugnet LA. 2026.Asteroseismology. In: Encyclopedia of Astrophysics. vol. 2, 133–153.","apa":"Bowman, D. M., &#38; Bugnet, L. A. (2026). Asteroseismology. In I. Mandel (Ed.), <i>Encyclopedia of Astrophysics</i> (Vol. 2, pp. 133–153). Elsevier. <a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">https://doi.org/10.1016/b978-0-443-21439-4.00036-5</a>"},"department":[{"_id":"LiBu"}],"scopus_import":"1","external_id":{"arxiv":["2410.01715"]},"OA_type":"green","author":[{"full_name":"Bowman, Dominic M.","last_name":"Bowman","first_name":"Dominic M."},{"id":"d9edb345-f866-11ec-9b37-d119b5234501","first_name":"Lisa Annabelle","orcid":"0000-0003-0142-4000","full_name":"Bugnet, Lisa Annabelle","last_name":"Bugnet"}]},{"publication":"npj Systems Biology and Applications","file":[{"file_id":"21346","creator":"dernst","date_updated":"2026-02-23T10:09:03Z","file_name":"2026_npjSysBioApp_Arruda.pdf","success":1,"checksum":"99b2e6bbaaedf45f22e07751948669f5","date_created":"2026-02-23T10:09:03Z","file_size":10217687,"access_level":"open_access","content_type":"application/pdf","relation":"main_file"}],"abstract":[{"text":"To assess cell migration in complex spatial environments, microfabricated chips, such as mazes and pillar forests, are routinely used to impose spatial and mechanical constraints, and cell trajectories are followed within these structures by advanced imaging techniques. In systems mechanobiology, computational models serve as essential tools to uncover how physical geometry influences intracellular dynamics; however, decoding such complex behaviors requires advanced inference techniques. Here, we integrated experimental observations of dendritic cell migration in a geometrically constrained microenvironment into a Cellular Potts model. We demonstrated that these spatial constraints modulate the motility dynamics, including speed and directional changes. We show that classical summary statistics, such as mean squared displacement and turning angle distributions, can resolve key mechanistic features but fail to extract richer spatiotemporal patterns, limiting accurate parameter inference. To solve this, we applied neural posterior estimation with in-the-loop learning of summary features. This learned summary representation of the data enables robust and flexible parameter inference, providing a data-driven framework for model calibration and advancing quantitative analysis of cell migration in structured microenvironments.","lang":"eng"}],"publication_status":"published","DOAJ_listed":"1","doi":"10.1038/s41540-026-00648-9","publication_identifier":{"eissn":["2056-7189"]},"pmid":1,"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-16T10:44:31Z","publisher":"Springer Nature","article_type":"original","intvolume":"        12","day":"05","file_date_updated":"2026-02-23T10:09:03Z","OA_place":"publisher","citation":{"short":"J. Arruda, E. Alamoudi, R. Mueller, M. Vaisband, R. Molkenbur, J. Merrin, E. Kiermaier, J. Hasenauer, Npj Systems Biology and Applications 12 (2026).","ama":"Arruda J, Alamoudi E, Mueller R, et al. Simulation-based inference of cell migration dynamics in complex spatial environments. <i>npj Systems Biology and Applications</i>. 2026;12. doi:<a href=\"https://doi.org/10.1038/s41540-026-00648-9\">10.1038/s41540-026-00648-9</a>","chicago":"Arruda, Jonas, Emad Alamoudi, Robert Mueller, Marc Vaisband, Ronja Molkenbur, Jack Merrin, Eva Kiermaier, and Jan Hasenauer. “Simulation-Based Inference of Cell Migration Dynamics in Complex Spatial Environments.” <i>Npj Systems Biology and Applications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41540-026-00648-9\">https://doi.org/10.1038/s41540-026-00648-9</a>.","mla":"Arruda, Jonas, et al. “Simulation-Based Inference of Cell Migration Dynamics in Complex Spatial Environments.” <i>Npj Systems Biology and Applications</i>, vol. 12, 20, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41540-026-00648-9\">10.1038/s41540-026-00648-9</a>.","apa":"Arruda, J., Alamoudi, E., Mueller, R., Vaisband, M., Molkenbur, R., Merrin, J., … Hasenauer, J. (2026). Simulation-based inference of cell migration dynamics in complex spatial environments. <i>Npj Systems Biology and Applications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41540-026-00648-9\">https://doi.org/10.1038/s41540-026-00648-9</a>","ista":"Arruda J, Alamoudi E, Mueller R, Vaisband M, Molkenbur R, Merrin J, Kiermaier E, Hasenauer J. 2026. Simulation-based inference of cell migration dynamics in complex spatial environments. npj Systems Biology and Applications. 12, 20.","ieee":"J. Arruda <i>et al.</i>, “Simulation-based inference of cell migration dynamics in complex spatial environments,” <i>npj Systems Biology and Applications</i>, vol. 12. Springer Nature, 2026."},"type":"journal_article","article_processing_charge":"Yes (via OA deal)","oa":1,"department":[{"_id":"NanoFab"}],"acknowledgement":"This work was supported by the German Federal Ministry of Education and Research (BMBF) (EMUNE/031L0293C), the European Union via the ERC grant INTEGRATE, grant agreement number 101126146, and under Germany’s Excellence Strategy by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) (EXC 2047—390685813, EXC 2151—390873048, FOR5775 — 533863915, and 524747443), the University of Bonn via the Schlegel Professorship of J.H., and the returning experts fellowship of the Ministry of Innovation, Science, and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069). J.M. is a member of the Nanofabrication Facility and is supported by the Institute of Science and Technology Austria. E.K. acknowledges the TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments. The authors thank Laeschkir Würthner for his insightful comments on the implementation of the authors’ model. The views and opinions expressed are those of the authors only and do not necessarily reflect those of the funding agencies. Parts of Fig. 1 were created using BioRender. Open Access funding enabled and organized by Projekt DEAL.","OA_type":"gold","author":[{"first_name":"Jonas","full_name":"Arruda, Jonas","last_name":"Arruda"},{"full_name":"Alamoudi, Emad","last_name":"Alamoudi","first_name":"Emad"},{"first_name":"Robert","full_name":"Mueller, Robert","last_name":"Mueller"},{"last_name":"Vaisband","full_name":"Vaisband, Marc","first_name":"Marc"},{"last_name":"Molkenbur","full_name":"Molkenbur, Ronja","first_name":"Ronja"},{"full_name":"Merrin, Jack","last_name":"Merrin","first_name":"Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609"},{"full_name":"Kiermaier, Eva","last_name":"Kiermaier","first_name":"Eva"},{"full_name":"Hasenauer, Jan","last_name":"Hasenauer","first_name":"Jan"}],"article_number":"20","scopus_import":"1","external_id":{"pmid":["41611727"]},"_id":"21231","date_published":"2026-02-05T00:00:00Z","quality_controlled":"1","date_updated":"2026-02-23T10:10:10Z","language":[{"iso":"eng"}],"ddc":["570"],"year":"2026","month":"02","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","status":"public","PlanS_conform":"1","volume":12,"title":"Simulation-based inference of cell migration dynamics in complex spatial environments"}]