[{"publication":"Astronomy & Astrophysics","file_date_updated":"2026-02-24T07:46:47Z","intvolume":" 706","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank the anonymous referee for the insightful comments that helped improving this paper. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations were taken under programmes # 1243, # 1933 and # 3516. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. GK acknowledges support from the Foundation MERAC. APV acknowledge support from the Sussex Astronomy Centre STFC Consolidated Grant (ST/X001040/1).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_status":"published","publisher":"EDP Sciences","oa_version":"Published Version","date_published":"2026-02-01T00:00:00Z","volume":706,"external_id":{"arxiv":["2510.19959"]},"citation":{"ieee":"G. Kotiwale et al., “Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy,” Astronomy & Astrophysics, vol. 706. EDP Sciences, 2026.","chicago":"Kotiwale, Gauri, Jorryt J Matthee, Daichi Kashino, Aswin P. Vijayan, Alberto Torralba Torregrosa, Claudia Di Cesare, Edoardo Iani, et al. “Rapid, out-of-Equilibrium Metal Enrichment Indicated by a Flat Mass-Metallicity Relation at z ∼ 6 from NIRCam Grism Spectroscopy.” Astronomy & Astrophysics. EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202556597.","apa":"Kotiwale, G., Matthee, J. J., Kashino, D., Vijayan, A. P., Torralba Torregrosa, A., Di Cesare, C., … Sobral, D. (2026). Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202556597","ista":"Kotiwale G, Matthee JJ, Kashino D, Vijayan AP, Torralba Torregrosa A, Di Cesare C, Iani E, Bordoloi R, Leja J, Maseda MV, Tacchella S, Shivaei I, Heintz KE, Danhaive AL, Mascia S, Kramarenko I, Navarrete B, Mackenzie R, Naidu RP, Sobral D. 2026. Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. Astronomy & Astrophysics. 706, A165.","short":"G. Kotiwale, J.J. Matthee, D. Kashino, A.P. Vijayan, A. Torralba Torregrosa, C. Di Cesare, E. Iani, R. Bordoloi, J. Leja, M.V. Maseda, S. Tacchella, I. Shivaei, K.E. Heintz, A.L. Danhaive, S. Mascia, I. Kramarenko, B. Navarrete, R. Mackenzie, R.P. Naidu, D. Sobral, Astronomy & Astrophysics 706 (2026).","mla":"Kotiwale, Gauri, et al. “Rapid, out-of-Equilibrium Metal Enrichment Indicated by a Flat Mass-Metallicity Relation at z ∼ 6 from NIRCam Grism Spectroscopy.” Astronomy & Astrophysics, vol. 706, A165, EDP Sciences, 2026, doi:10.1051/0004-6361/202556597.","ama":"Kotiwale G, Matthee JJ, Kashino D, et al. Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. Astronomy & Astrophysics. 2026;706. doi:10.1051/0004-6361/202556597"},"publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"department":[{"_id":"JoMa"},{"_id":"GradSch"}],"language":[{"iso":"eng"}],"OA_type":"diamond","OA_place":"publisher","has_accepted_license":"1","date_updated":"2026-02-24T07:49:42Z","article_processing_charge":"No","_id":"21341","abstract":[{"lang":"eng","text":"We aim to characterise the mass-metallicity relation (MZR) and the 3D correlation between the stellar mass, metallicity, and star formation rate (SFR) known as the fundamental metallicity relation (FMR) for galaxies at 5 < z < 7. Using ∼800 [O III] selected galaxies from deep NIRCam grism surveys, we present our stacked measurements of direct-Te metallicities, which we used to test recent strong-line metallicity calibrations. Our measured direct-Te metallicities (0.1–0.2 Z⊙ for M★ ≈ 5 × 107 − 9 M⊙, respectively) match recent JWST/NIRSpec-based results. However, there are significant inconsistencies between observations and hydrodynamical simulations. We observe a flatter MZR slope than the SPHINX20 and FLARES simulations, which cannot be attributed to selection effects. With simple models, we show that the effect of an [O III] flux-limited sample on the observed shape of the MZR is strongly dependent on the FMR. If the FMR is similar to the one in the local Universe, the intrinsic high-redshift MZR should be even flatter than is observed. In turn, a 3D relation where SFR correlates positively with metallicity at fixed mass would imply an intrinsically steeper MZR. Our measurements indicate that metallicity variations at fixed mass show little dependence on the SFR, suggesting a flat intrinsic MZR. This could indicate that the low-mass galaxies at these redshifts are out of equilibrium and that metal enrichment occurs rapidly in low-mass galaxies. However, being limited by our stacking analysis, we are yet to probe the scatter in the MZR and its dependence on SFR. Large carefully selected samples of galaxies with robust metallicity measurements can put tight constraints on the high-redshift FMR and help us to understand the interplay between gas flows, star formation, and feedback in early galaxies."}],"date_created":"2026-02-22T23:01:35Z","oa":1,"file":[{"file_name":"2026_AstronomyAstrophysics_Kotiwale.pdf","content_type":"application/pdf","date_created":"2026-02-24T07:46:47Z","success":1,"checksum":"6f5849d29ad43bee32f90152f6fc0294","file_size":6531719,"file_id":"21355","relation":"main_file","creator":"dernst","access_level":"open_access","date_updated":"2026-02-24T07:46:47Z"}],"type":"journal_article","corr_author":"1","quality_controlled":"1","arxiv":1,"status":"public","author":[{"last_name":"Kotiwale","first_name":"Gauri","full_name":"Kotiwale, Gauri","id":"1438afc8-1ff6-11ee-9fa6-cd4a75d66875"},{"id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee","first_name":"Jorryt J"},{"last_name":"Kashino","first_name":"Daichi","full_name":"Kashino, Daichi"},{"last_name":"Vijayan","first_name":"Aswin P.","full_name":"Vijayan, Aswin P."},{"id":"018f0249-0e87-11f0-b167-cbce08fbd541","full_name":"Torralba Torregrosa, Alberto","orcid":"0000-0001-5586-6950","first_name":"Alberto","last_name":"Torralba Torregrosa"},{"last_name":"Di Cesare","first_name":"Claudia","full_name":"Di Cesare, Claudia","id":"2d002343-372f-11ef-98ec-a164d20427cb"},{"last_name":"Iani","first_name":"Edoardo","orcid":"0000-0001-8386-3546","full_name":"Iani, Edoardo","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a"},{"full_name":"Bordoloi, Rongmon","first_name":"Rongmon","last_name":"Bordoloi"},{"first_name":"Joel","last_name":"Leja","full_name":"Leja, Joel"},{"first_name":"Michael V.","last_name":"Maseda","full_name":"Maseda, Michael V."},{"full_name":"Tacchella, Sandro","last_name":"Tacchella","first_name":"Sandro"},{"last_name":"Shivaei","first_name":"Irene","full_name":"Shivaei, Irene"},{"full_name":"Heintz, Kasper E.","last_name":"Heintz","first_name":"Kasper E."},{"last_name":"Danhaive","first_name":"A. Lola","full_name":"Danhaive, A. Lola"},{"id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","full_name":"Mascia, Sara","last_name":"Mascia","first_name":"Sara"},{"orcid":"0000-0001-5346-6048","last_name":"Kramarenko","first_name":"Ivan","full_name":"Kramarenko, Ivan","id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4"},{"id":"aa14a535-50c9-11ef-b52e-e0c373d10148","full_name":"Navarrete, Benjamín","first_name":"Benjamín","last_name":"Navarrete"},{"full_name":"Mackenzie, Ruari","first_name":"Ruari","last_name":"Mackenzie"},{"first_name":"Rohan P.","last_name":"Naidu","full_name":"Naidu, Rohan P."},{"first_name":"David","last_name":"Sobral","full_name":"Sobral, David"}],"project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"doi":"10.1051/0004-6361/202556597","year":"2026","DOAJ_listed":"1","day":"01","scopus_import":"1","article_number":"A165","article_type":"original","ddc":["520"],"PlanS_conform":"1","month":"02","title":"Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy"},{"month":"01","title":"A cosmic miracle: A remarkably luminous galaxy at zspec = 14.44 confirmed with JWST","ddc":["520"],"PlanS_conform":"1","article_type":"original","author":[{"full_name":"Naidu, Rohan P.","first_name":"Rohan P.","last_name":"Naidu"},{"first_name":"Pascal A.","last_name":"Oesch","full_name":"Oesch, Pascal A."},{"full_name":"Brammer, Gabriel","first_name":"Gabriel","last_name":"Brammer"},{"full_name":"Weibel, Andrea","first_name":"Andrea","last_name":"Weibel"},{"first_name":"Yijia","last_name":"Li","full_name":"Li, Yijia"},{"orcid":"0000-0003-2871-127X","first_name":"Jorryt J","last_name":"Matthee","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720"},{"full_name":"Chisholm, John","last_name":"Chisholm","first_name":"John"},{"last_name":"Pollock","first_name":"Clara L.","full_name":"Pollock, Clara L."},{"first_name":"Kasper E.","last_name":"Heintz","full_name":"Heintz, Kasper E."},{"full_name":"Johnson, Benjamin D.","last_name":"Johnson","first_name":"Benjamin D."},{"last_name":"Shen","first_name":"Xuejian","full_name":"Shen, Xuejian"},{"full_name":"Hviding, Raphael E.","first_name":"Raphael E.","last_name":"Hviding"},{"last_name":"Leja","first_name":"Joel","full_name":"Leja, Joel"},{"last_name":"Tacchella","first_name":"Sandro","full_name":"Tacchella, Sandro"},{"full_name":"Ganguly, Arpita","first_name":"Arpita","last_name":"Ganguly"},{"last_name":"Witten","first_name":"Callum","full_name":"Witten, Callum"},{"first_name":"Hakim","last_name":"Atek","full_name":"Atek, Hakim"},{"full_name":"Belli, Sirio","first_name":"Sirio","last_name":"Belli"},{"first_name":"Sownak","last_name":"Bose","full_name":"Bose, Sownak"},{"last_name":"Bouwens","first_name":"Rychard","full_name":"Bouwens, Rychard"},{"last_name":"Dayal","first_name":"Pratika","full_name":"Dayal, Pratika"},{"first_name":"Roberto","last_name":"Decarli","full_name":"Decarli, Roberto"},{"last_name":"De Graaff","first_name":"Anna","full_name":"De Graaff, Anna"},{"last_name":"Fudamoto","first_name":"Yoshinobu","full_name":"Fudamoto, Yoshinobu"},{"last_name":"Giovinazzo","first_name":"Emma","full_name":"Giovinazzo, Emma"},{"full_name":"Greene, Jenny E.","first_name":"Jenny E.","last_name":"Greene"},{"last_name":"Illingworth","first_name":"Garth","full_name":"Illingworth, Garth"},{"first_name":"Akio K.","last_name":"Inoue","full_name":"Inoue, Akio K."},{"last_name":"Kane","first_name":"Sarah G.","full_name":"Kane, Sarah G."},{"first_name":"Ivo","last_name":"Labbe","full_name":"Labbe, Ivo"},{"last_name":"Leonova","first_name":"Ecaterina","full_name":"Leonova, Ecaterina"},{"full_name":"Marques-Chaves, Rui","last_name":"Marques-Chaves","first_name":"Rui"},{"full_name":"Meyer, Romain A.","last_name":"Meyer","first_name":"Romain A."},{"full_name":"Nelson, Erica J.","first_name":"Erica J.","last_name":"Nelson"},{"last_name":"Roberts-Borsani","first_name":"Guido","full_name":"Roberts-Borsani, Guido"},{"full_name":"Schaerer, Daniel","last_name":"Schaerer","first_name":"Daniel"},{"full_name":"Simcoe, Robert A.","last_name":"Simcoe","first_name":"Robert A."},{"last_name":"Stefanon","first_name":"Mauro","full_name":"Stefanon, Mauro"},{"first_name":"Yuma","last_name":"Sugahara","full_name":"Sugahara, Yuma"},{"first_name":"Sune","last_name":"Toft","full_name":"Toft, Sune"},{"last_name":"Van Der Wel","first_name":"Arjen","full_name":"Van Der Wel, Arjen"},{"first_name":"Pieter","last_name":"Van Dokkum","full_name":"Van Dokkum, Pieter"},{"first_name":"Fabian","last_name":"Walter","full_name":"Walter, Fabian"},{"full_name":"Watson, Darach","last_name":"Watson","first_name":"Darach"},{"full_name":"Weaver, John R.","first_name":"John R.","last_name":"Weaver"},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"}],"project":[{"name":"Young galaxies as tracers and agents of cosmic reionization","grant_number":"101076224","_id":"bd9b2118-d553-11ed-ba76-db24564edfea"}],"doi":"10.33232/001c.156033","year":"2026","day":"30","scopus_import":"1","quality_controlled":"1","arxiv":1,"status":"public","oa":1,"type":"journal_article","abstract":[{"lang":"eng","text":"JWST has revealed a stunning population of bright galaxies at surprisingly early epochs, z > 10,\r\nwhere few such sources were expected. Here we present the most distant example of this class yet – MoM-z14, a luminous (MUV = −20.2) source in the COSMOS legacy field at zspec = 14.44+0.02−0.02 that expands the observational frontier to a mere 280 million years after the Big Bang. The redshift is confirmed with NIRSpec/prism spectroscopy through a sharp Lyman-α break and ≈ 3σ detections of five rest-UV emission lines. The number density of bright zspec ≈ 14 − 15 sources implied by our “Mirage or Miracle” survey spanning ≈ 350 arcmin2 is > 100× larger (182+329 −105×) than pre-JWST consensus models. The high EWs of UV lines (≈15−35˚A) signal a rising star-formation history, with a ≈10× increase in the last 5 Myr (SFR5Myr/SFR50Myr = 9.9 +3.0 −5.8). The source is extremely compact (circularized re = 74+15\r\n−12 pc), and yet elongated (b/a = 0.25+0.11−0.06), suggesting an AGN is not the dominant source of UV light. The steep UV slope (β = −2.5 +0.2 −0.2) implies negligible dust attenuation\r\nand a young stellar population. The absence of a strong damping wing provides tentative evidence that the immediate surroundings of MoM-z14 may be partially ionized at a redshift where virtually every reionization model predicts a ≈ 100% neutral fraction. The nitrogen emission and highly supersolar [N/C]> 1 hint at an abundance pattern similar to local globular clusters that may have once hosted luminous supermassive stars. Since this abundance pattern is also common among the most ancient stars born in the Milky Way, we may be directly witnessing the formation of such stars in dense clusters, connecting galaxy evolution across the entire sweep of cosmic time. "}],"main_file_link":[{"url":"https://doi.org/10.33232/001c.156033","open_access":"1"}],"date_created":"2026-02-22T23:01:35Z","date_updated":"2026-02-24T07:37:17Z","article_processing_charge":"No","_id":"21342","OA_place":"publisher","OA_type":"diamond","language":[{"iso":"eng"}],"has_accepted_license":"1","external_id":{"arxiv":["2505.11263"]},"citation":{"ista":"Naidu RP, Oesch PA, Brammer G, Weibel A, Li Y, Matthee JJ, Chisholm J, Pollock CL, Heintz KE, Johnson BD, Shen X, Hviding RE, Leja J, Tacchella S, Ganguly A, Witten C, Atek H, Belli S, Bose S, Bouwens R, Dayal P, Decarli R, De Graaff A, Fudamoto Y, Giovinazzo E, Greene JE, Illingworth G, Inoue AK, Kane SG, Labbe I, Leonova E, Marques-Chaves R, Meyer RA, Nelson EJ, Roberts-Borsani G, Schaerer D, Simcoe RA, Stefanon M, Sugahara Y, Toft S, Van Der Wel A, Van Dokkum P, Walter F, Watson D, Weaver JR, Whitaker KE. 2026. A cosmic miracle: A remarkably luminous galaxy at zspec = 14.44 confirmed with JWST. The Open Journal of Astrophysics. 9.","short":"R.P. Naidu, P.A. Oesch, G. Brammer, A. Weibel, Y. Li, J.J. Matthee, J. Chisholm, C.L. Pollock, K.E. Heintz, B.D. Johnson, X. Shen, R.E. Hviding, J. Leja, S. Tacchella, A. Ganguly, C. Witten, H. Atek, S. Belli, S. Bose, R. Bouwens, P. Dayal, R. Decarli, A. De Graaff, Y. Fudamoto, E. Giovinazzo, J.E. Greene, G. Illingworth, A.K. Inoue, S.G. Kane, I. Labbe, E. Leonova, R. Marques-Chaves, R.A. Meyer, E.J. Nelson, G. Roberts-Borsani, D. Schaerer, R.A. Simcoe, M. Stefanon, Y. Sugahara, S. Toft, A. Van Der Wel, P. Van Dokkum, F. Walter, D. Watson, J.R. Weaver, K.E. Whitaker, The Open Journal of Astrophysics 9 (2026).","mla":"Naidu, Rohan P., et al. “A Cosmic Miracle: A Remarkably Luminous Galaxy at Zspec = 14.44 Confirmed with JWST.” The Open Journal of Astrophysics, vol. 9, Maynooth Academic Publishing, 2026, doi:10.33232/001c.156033.","ama":"Naidu RP, Oesch PA, Brammer G, et al. A cosmic miracle: A remarkably luminous galaxy at zspec = 14.44 confirmed with JWST. The Open Journal of Astrophysics. 2026;9. doi:10.33232/001c.156033","apa":"Naidu, R. P., Oesch, P. A., Brammer, G., Weibel, A., Li, Y., Matthee, J. J., … Whitaker, K. E. (2026). A cosmic miracle: A remarkably luminous galaxy at zspec = 14.44 confirmed with JWST. The Open Journal of Astrophysics. Maynooth Academic Publishing. https://doi.org/10.33232/001c.156033","ieee":"R. P. Naidu et al., “A cosmic miracle: A remarkably luminous galaxy at zspec = 14.44 confirmed with JWST,” The Open Journal of Astrophysics, vol. 9. Maynooth Academic Publishing, 2026.","chicago":"Naidu, Rohan P., Pascal A. Oesch, Gabriel Brammer, Andrea Weibel, Yijia Li, Jorryt J Matthee, John Chisholm, et al. “A Cosmic Miracle: A Remarkably Luminous Galaxy at Zspec = 14.44 Confirmed with JWST.” The Open Journal of Astrophysics. Maynooth Academic Publishing, 2026. https://doi.org/10.33232/001c.156033."},"publication_identifier":{"eissn":["2565-6120"]},"department":[{"_id":"JoMa"}],"oa_version":"Published Version","volume":9,"date_published":"2026-01-30T00:00:00Z","publication_status":"published","publisher":"Maynooth Academic Publishing","acknowledgement":"We thank the two anonymous referees for their insightful comments that have strengthened this work. “Mirage or Miracle” is but the latest link in a long chain of surveys that have built COSMOS into a premier extragalactic legacy field. We are thankful to all the teams who have contributed to this legacy, particularly those mentioned in §3 for leading recent JWST programs whose imaging\r\nwe have incorporated in our analysis. We are grateful to Vasily Belokurov for help in compiling the Milky Way reference sample featured in Fig 8. We thank Danielle Berg for sharing a highly complete, highly decimalized NUV vacuum line list. We are grateful to our program’s NIRSpec reviewer, Dan Coe, and program coordinator, Allison Vick, for valuable input on our MSA design. We acknowledge illuminating conversations with Risa Wechsler and Chao-Lin Kuo about early reionization. RPN thanks Neil Pappalardo and Jane Pappalardo for their generous support of the MIT Pappalardo Fellowships in Physics, and for their enthusiasm and encouragement for seeking galaxies at the highest redshifts. RPN acknowledges funding from JWST program GO5224. Support for this work was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020 207349. Funded by the European Union (ERC, AGENTS, 101076224 and HEAVYMETAL, 101071865). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of\r\nthe European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant DNRF140. This work has also been supported by JSPS KAKENHI Grant Number 23H00131. HA acknowledges support from CNES, focused on the JWST mission, and the Programme National Cosmology and Galaxies (PNCG)\r\nof CNRS/INSU with INP and IN2P3, co-funded by CEA and CNES. HA is supported by the French National Research Agency (ANR) under the project FIRSTGAL, grant number ANR-24-CE31-0838. SB is supported by the UK Research and Innovation (UKRI) Future Leaders Fellowship [grant number MR/V023381/1]. R.D. acknowledges support from the INAF GO 2022\r\ngrant “The birth of the giants: JWST sheds light on the build-up of quasars at cosmic dawn” and by the PRIN MUR “2022935STW”, RFF M4.C2.1.1, CUP J53D23001570006 and C53D23000950006. Computations supporting this paper were run on MIT’s Engaging cluster. This publication made use of the NASA Astrophysical Data System for bibliographic information. Some of the data products presented herein were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. Software used in developing this work includes: matplotlib (Hunter 2007), jupyter (Kluyver et al. 2016), IPython (P´erez & Granger 2007), numpy (Oliphant 2015), scipy (Virtanen et al. 2020), TOPCAT (Taylor 2005), and Astropy (Astropy Collaboration et al. 2013).This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space\r\nTelescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program # 5224.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"The Open Journal of Astrophysics","intvolume":" 9","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"publisher":"Springer Nature","publication_status":"epub_ahead","oa_version":"Published Version","ec_funded":1,"date_published":"2026-02-20T00:00:00Z","publication":"Earth Systems and Environment","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"EAL-B and CP-R received support from Sergio Arboleda University through project No. IN.BG.086.24.014. AC acknowledges support by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. We thank two anonymous reviewers for thein insightful comments that largely improve the manuscript. Open access funding provided by Institute of Science and Technology (IST Austria). This work was funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. The work also received funding from Sergio Arboleda University through project No. IN.BG.086.24.014.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"article_processing_charge":"Yes (via OA deal)","date_updated":"2026-02-24T08:02:58Z","_id":"21344","department":[{"_id":"CaMu"}],"citation":{"ama":"Bustos D, Garcia D, Rojas NY, Lopez-Barrera EA, Peña-Rincon C, Casallas Garcia A. Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. Earth Systems and Environment. 2026. doi:10.1007/s41748-026-01052-3","mla":"Bustos, Daniela, et al. “Ozone Trends and Mortality Risk: The Growing Need for Machine Learning Predictions in Bogotá, Colombia.” Earth Systems and Environment, Springer Nature, 2026, doi:10.1007/s41748-026-01052-3.","short":"D. Bustos, D. Garcia, N.Y. Rojas, E.A. Lopez-Barrera, C. Peña-Rincon, A. Casallas Garcia, Earth Systems and Environment (2026).","ista":"Bustos D, Garcia D, Rojas NY, Lopez-Barrera EA, Peña-Rincon C, Casallas Garcia A. 2026. Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. Earth Systems and Environment.","apa":"Bustos, D., Garcia, D., Rojas, N. Y., Lopez-Barrera, E. A., Peña-Rincon, C., & Casallas Garcia, A. (2026). Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. Earth Systems and Environment. Springer Nature. https://doi.org/10.1007/s41748-026-01052-3","chicago":"Bustos, Daniela, Diana Garcia, Nestor Y. Rojas, Ellie A. Lopez-Barrera, Carlos Peña-Rincon, and Alejandro Casallas Garcia. “Ozone Trends and Mortality Risk: The Growing Need for Machine Learning Predictions in Bogotá, Colombia.” Earth Systems and Environment. Springer Nature, 2026. https://doi.org/10.1007/s41748-026-01052-3.","ieee":"D. Bustos, D. Garcia, N. Y. Rojas, E. A. Lopez-Barrera, C. Peña-Rincon, and A. Casallas Garcia, “Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia,” Earth Systems and Environment. Springer Nature, 2026."},"publication_identifier":{"eissn":["2509-9434"],"issn":["2509-9426"]},"has_accepted_license":"1","OA_type":"hybrid","OA_place":"publisher","language":[{"iso":"eng"}],"corr_author":"1","quality_controlled":"1","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s41748-026-01052-3"}],"abstract":[{"lang":"eng","text":"Tropospheric ozone has the potential to become an increasingly pressing public health issue in Bogotá, Colombia, due to rising concentrations across the city driven by complex interactions among emissions, meteorology, and urban structure. This study presents a comprehensive spatiotemporal analysis of ozone levels from 2013 to 2023 and assesses the associated health burden using mortality data from the same period. Results reveal a consistent upward trend in ozone concentrations, particularly in northern, western, and southern localities, with seasonal peaks linked to biomass burning and photochemical conditions. Mortality analysis, based on the Global Exposure Mortality Model, estimates that 18.3% of all deaths among individuals aged 25 and older are attributable to long-term ozone exposure. The highest burdens are found in densely populated and socioeconomically vulnerable areas such as Kennedy, Suba, and Ciudad Bolívar, with the elderly being the most affected. Building on these findings, we developed a machine learning prediction model for ozone using a convolutional merge with a long-short term memory network architecture trained on air quality and meteorological variables. The model demonstrated strong predictive performance (mean Rho=0.86, RMSE=3.5 μg/m3) across monitoring stations (17 with at least 35000 data points), supporting its potential application in real-time early warning systems across Bogotá. This integrated approach highlights the importance of localized air quality management, combining epidemiological assessment with predictive modeling. The findings underscore the urgency of implementing region-specific mitigation strategies and improving monitoring infrastructure to reduce health risks from ozone exposure in Bogotá’s rapidly growing urban environment."}],"date_created":"2026-02-23T08:26:51Z","oa":1,"type":"journal_article","PlanS_conform":"1","ddc":["550"],"month":"02","title":"Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia","year":"2026","doi":"10.1007/s41748-026-01052-3","author":[{"first_name":"Daniela","last_name":"Bustos","full_name":"Bustos, Daniela"},{"last_name":"Garcia","first_name":"Diana","full_name":"Garcia, Diana"},{"full_name":"Rojas, Nestor Y.","first_name":"Nestor Y.","last_name":"Rojas"},{"full_name":"Lopez-Barrera, Ellie A.","last_name":"Lopez-Barrera","first_name":"Ellie A."},{"full_name":"Peña-Rincon, Carlos","first_name":"Carlos","last_name":"Peña-Rincon"},{"id":"92081129-2d75-11ef-a48d-b04dd7a2385a","full_name":"Casallas Garcia, Alejandro","first_name":"Alejandro","last_name":"Casallas Garcia","orcid":"0000-0002-1988-5035"}],"project":[{"grant_number":"101034413","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"day":"20","article_type":"original"},{"status":"public","corr_author":"1","file":[{"creator":"sriegler","access_level":"closed","date_updated":"2026-03-02T10:59:50Z","relation":"source_file","file_id":"21386","checksum":"2f1f44e8536c2538f94a440217452c9f","file_size":31430022,"file_name":"2026_Riegler_Stefan_Thesis.zip","date_created":"2026-03-02T10:59:50Z","content_type":"application/x-zip-compressed"},{"file_size":11635090,"checksum":"2e8dc39640bc26ae5684c944c619719b","file_id":"21387","relation":"main_file","date_updated":"2026-03-02T10:59:49Z","creator":"sriegler","access_level":"closed","embargo_to":"open_access","content_type":"application/pdf","date_created":"2026-03-02T10:59:49Z","file_name":"2026_Riegler_Stefan_Thesis.pdf","embargo":"2027-02-27"}],"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"type":"dissertation","date_created":"2026-02-27T09:08:14Z","month":"02","title":"Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species","ddc":["570","575","583"],"degree_awarded":"PhD","related_material":{"record":[{"id":"21363","status":"public","relation":"research_data"}]},"author":[{"orcid":"0000-0003-3413-1343","first_name":"Stefan","last_name":"Riegler","full_name":"Riegler, Stefan","id":"FF6018E0-D806-11E9-8E43-0B14E6697425"}],"project":[{"name":"Breeding for coffee and cocoa root resilience in low input farming systems based on improved rootstocks","_id":"34afa094-11ca-11ed-8bc3-a375845a59fb","grant_number":"101060393"}],"doi":"10.15479/AT-ISTA-21360","year":"2026","day":"26","page":"185","oa_version":"Published Version","date_published":"2026-02-26T00:00:00Z","publication_status":"published","publisher":"Institute of Science and Technology Austria","supervisor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","last_name":"Benková","first_name":"Eva","orcid":"0000-0002-8510-9739"}],"acknowledgement":"I would like to acknowledge the Austrian Academy of Sciences (ÖAW) and European\r\nResearch Executive Agency (REA) for funding my research (DOC ÖAW Fellowship\r\n26130, Horizon Europe BOLERO Project 101060393). ","alternative_title":["ISTA Thesis"],"tmp":{"image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)"},"license":"https://creativecommons.org/licenses/by-sa/4.0/","file_date_updated":"2026-03-02T10:59:50Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_updated":"2026-03-09T12:20:56Z","article_processing_charge":"No","_id":"21360","language":[{"iso":"eng"}],"OA_place":"repository","has_accepted_license":"1","citation":{"ieee":"S. Riegler, “Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species,” Institute of Science and Technology Austria, 2026.","chicago":"Riegler, Stefan. “Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21360.","ista":"Riegler S. 2026. Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria.","short":"S. Riegler, Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species, Institute of Science and Technology Austria, 2026.","ama":"Riegler S. Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. 2026. doi:10.15479/AT-ISTA-21360","mla":"Riegler, Stefan. Root System Plasticity under Nutrient Limitation : Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21360.","apa":"Riegler, S. (2026). Root system plasticity under nutrient limitation : Investigating hormonal and molecular drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21360"},"publication_identifier":{"issn":["2663-337X"]},"department":[{"_id":"GradSch"},{"_id":"EvBe"}]},{"ddc":["575"],"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"21360"}]},"date_updated":"2026-03-09T12:20:56Z","article_processing_charge":"No","month":"02","_id":"21363","title":"Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species","author":[{"full_name":"Riegler, Stefan","id":"FF6018E0-D806-11E9-8E43-0B14E6697425","first_name":"Stefan","last_name":"Riegler","orcid":"0000-0003-3413-1343"}],"year":"2026","doi":"10.15479/AT-ISTA-21363","day":"27","citation":{"chicago":"Riegler, Stefan. “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species.” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21363.","ieee":"S. Riegler, “Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species.” Institute of Science and Technology Austria, 2026.","ama":"Riegler S. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species. 2026. doi:10.15479/AT-ISTA-21363","mla":"Riegler, Stefan. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis Thaliana and Coffea Species. Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21363.","ista":"Riegler S. 2026. Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21363.","short":"S. Riegler, (2026).","apa":"Riegler, S. (2026). Thesis Data for Root System Plasticity under Nutrient Limitation: Investigating Hormonal and Molecular Drivers in Arabidopsis thaliana and Coffea species. Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21363"},"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"has_accepted_license":"1","contributor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","contributor_type":"supervisor","orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva"}],"corr_author":"1","publisher":"Institute of Science and Technology Austria","oa_version":"None","date_published":"2026-02-27T00:00:00Z","status":"public","abstract":[{"text":"The data contains information on coffee differential gene expression as well as co-expression and trait correlations in two separate experiments. First, contrasting nitrogen supply, second, intra- and interspecific grafting.","lang":"eng"}],"date_created":"2026-02-27T09:18:41Z","file_date_updated":"2026-02-27T09:13:11Z","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","file":[{"embargo":"2027-02-27","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","date_created":"2026-02-27T09:11:33Z","embargo_to":"open_access","file_name":"SupplementaryTables.xlsx","date_updated":"2026-02-27T09:11:33Z","access_level":"closed","creator":"sriegler","relation":"main_file","file_id":"21364","file_size":63749444,"checksum":"de9145fa166a28c588b5184a2d3d4fee"},{"file_size":124,"checksum":"ce1f163551c96cee45943a8ea29720b6","file_id":"21365","relation":"main_file","date_updated":"2026-02-27T09:13:11Z","access_level":"closed","creator":"sriegler","content_type":"text/plain","date_created":"2026-02-27T09:13:11Z","embargo_to":"open_access","file_name":"ReadMe.txt","embargo":"2027-02-27"}],"tmp":{"image":"/images/cc_by_sa.png","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","short":"CC BY-SA (4.0)"},"type":"research_data"},{"date_updated":"2026-03-02T09:36:48Z","article_processing_charge":"Yes","_id":"21369","external_id":{"pmid":["41708600"]},"citation":{"chicago":"Hu, Jing, Tom Scheidt, Dev Thacker, Emil Axell, Elin Stemme, Urszula Łapińska, Stefan Wennmalm, et al. “Structural Defects in Amyloid-β Fibrils Drive Secondary Nucleation.” Nature Communications. Springer Nature, 2026. https://doi.org/10.1038/s41467-026-69377-1.","ieee":"J. Hu et al., “Structural defects in amyloid-β fibrils drive secondary nucleation,” Nature Communications, vol. 17. Springer Nature, 2026.","apa":"Hu, J., Scheidt, T., Thacker, D., Axell, E., Stemme, E., Łapińska, U., … Dear, A. J. (2026). Structural defects in amyloid-β fibrils drive secondary nucleation. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-026-69377-1","ama":"Hu J, Scheidt T, Thacker D, et al. Structural defects in amyloid-β fibrils drive secondary nucleation. Nature Communications. 2026;17. doi:10.1038/s41467-026-69377-1","mla":"Hu, Jing, et al. “Structural Defects in Amyloid-β Fibrils Drive Secondary Nucleation.” Nature Communications, vol. 17, 1933, Springer Nature, 2026, doi:10.1038/s41467-026-69377-1.","ista":"Hu J, Scheidt T, Thacker D, Axell E, Stemme E, Łapińska U, Wennmalm S, Meisl G, Curk S, Andreasen M, Vendruscolo M, Arosio P, Šarić A, Schmit JD, Knowles TPJ, Sparr E, Linse S, Michaels TCT, Dear AJ. 2026. Structural defects in amyloid-β fibrils drive secondary nucleation. Nature Communications. 17, 1933.","short":"J. Hu, T. Scheidt, D. Thacker, E. Axell, E. Stemme, U. Łapińska, S. Wennmalm, G. Meisl, S. Curk, M. Andreasen, M. Vendruscolo, P. Arosio, A. Šarić, J.D. Schmit, T.P.J. Knowles, E. Sparr, S. Linse, T.C.T. Michaels, A.J. Dear, Nature Communications 17 (2026)."},"publication_identifier":{"eissn":["2041-1723"]},"pmid":1,"department":[{"_id":"AnSa"}],"OA_type":"gold","language":[{"iso":"eng"}],"OA_place":"publisher","has_accepted_license":"1","publication_status":"published","publisher":"Springer Nature","ec_funded":1,"oa_version":"Published Version","volume":17,"date_published":"2026-02-20T00:00:00Z","publication":"Nature Communications","file_date_updated":"2026-03-02T09:34:18Z","intvolume":" 17","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"This work was supported by the Swedish Research Council (2019-02397 to E.S., 2015-00143 to S.L., and 2022-06641 to S.L. and E.S.), and the GenerationNano project, the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 945378 (S.L. co-PI). We acknowledge support from the Wellcome Trust (T.P.J.K.), the Cambridge Centre for Misfolding Diseases (T.P.J.K.), the BBSRC (T.P.J.K.), the Frances and Augustus Newman Foundation (T.P.J.K.), the ERC PhysProt (agreement n 337969) (T.S., T.P.J.K., S.L.), ETC StG “NEPA” (A.Š. and S.C.), the Royal Society (S.C., A.S.), the ERASMUS Programme (T.S.), and The Danish Council for Independent Research ∣ Natural Sciences (FNU-11-113326) (M.A.). This work was also funded by the Novo Nordisk Foundation (#NNF19OC0054635 to S.L.), ETH Zürich (T.C.T.M.), and the Swiss National Science Foundation (grant no 219703 to A.J.D. and T.C.T.M.). We acknowledge the use of the nano-Characterisation and nano-Manufacturing Research Equipment (nCHREM) facility for access to microscopy instrumentation. We are grateful to the late Professor Sir Christopher Dobson for invaluable conversations regarding the microfluidic diffusional sizing experiments. We are also grateful to Quentin A. E. Peter and Thomas Müller for their guidance on microfluidic device design. The cuvette-filled icon in Fig. 3d is by Servier [https://smart.servier.com/]. It is licensed under CC-BY 3.0 Unported [https://creativecommons.org/licenses/by/3.0/]. The authors would like to acknowledge Umeå Centre for Electron Microscopy (UCEM) for technical assistance and access to electron microscopy. Support was provided by SciLifeLab national Cryo-EM Unit at Umeå University.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"ddc":["570"],"PlanS_conform":"1","month":"02","title":"Structural defects in amyloid-β fibrils drive secondary nucleation","project":[{"name":"Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines","_id":"eba2549b-77a9-11ec-83b8-a81e493eae4e","grant_number":"802960","call_identifier":"H2020"}],"author":[{"full_name":"Hu, Jing","last_name":"Hu","first_name":"Jing"},{"last_name":"Scheidt","first_name":"Tom","full_name":"Scheidt, Tom"},{"full_name":"Thacker, Dev","last_name":"Thacker","first_name":"Dev"},{"last_name":"Axell","first_name":"Emil","full_name":"Axell, Emil"},{"first_name":"Elin","last_name":"Stemme","full_name":"Stemme, Elin"},{"last_name":"Łapińska","first_name":"Urszula","full_name":"Łapińska, Urszula"},{"full_name":"Wennmalm, Stefan","first_name":"Stefan","last_name":"Wennmalm"},{"full_name":"Meisl, Georg","first_name":"Georg","last_name":"Meisl"},{"orcid":"0000-0001-6160-9766","last_name":"Curk","first_name":"Samo","id":"031eff0d-d481-11ee-8508-cd12a7a86e5b","full_name":"Curk, Samo"},{"full_name":"Andreasen, Maria","last_name":"Andreasen","first_name":"Maria"},{"full_name":"Vendruscolo, Michele","first_name":"Michele","last_name":"Vendruscolo"},{"full_name":"Arosio, Paolo","first_name":"Paolo","last_name":"Arosio"},{"id":"bf63d406-f056-11eb-b41d-f263a6566d8b","full_name":"Šarić, Anđela","orcid":"0000-0002-7854-2139","first_name":"Anđela","last_name":"Šarić"},{"last_name":"Schmit","first_name":"Jeremy D.","full_name":"Schmit, Jeremy D."},{"full_name":"Knowles, Tuomas P.J.","last_name":"Knowles","first_name":"Tuomas P.J."},{"first_name":"Emma","last_name":"Sparr","full_name":"Sparr, Emma"},{"last_name":"Linse","first_name":"Sara","full_name":"Linse, Sara"},{"first_name":"Thomas C.T.","last_name":"Michaels","full_name":"Michaels, Thomas C.T."},{"full_name":"Dear, Alexander J.","first_name":"Alexander J.","last_name":"Dear"}],"doi":"10.1038/s41467-026-69377-1","year":"2026","DOAJ_listed":"1","day":"20","scopus_import":"1","article_number":"1933","article_type":"original","quality_controlled":"1","status":"public","abstract":[{"text":"Formation of new amyloid fibrils and oligomers from monomeric protein on the surfaces of existing fibrils is an important driver of many disorders such as Alzheimer’s and Parkinson’s diseases. The structural basis of this secondary nucleation process, however, is poorly understood. Here, we ask whether secondary nucleation sites are found predominantly at rare growth defects: irregularities in the fibril core structure incorporated during their original assembly. We first demonstrate using the specific inhibitor of secondary nucleation, Brichos, that secondary nucleation sites on Alzheimer’s disease-associated fibrils composed of Aβ40 and Aβ42 peptides are rare compared to the number of protein molecules they contain. We then grow Aβ40 fibrils under conditions designed to eliminate most growth defects while leaving the regular fibril morphology unchanged, and confirm the latter using cryo-electron microscopy. We measure both the ability of these annealed fibrils to promote secondary nucleation and the stoichiometry of their secondary nucleation sites, finding that both are greatly reduced as predicted. Re-analysis of published data for other proteins suggests that fibril growth defects may also drive secondary nucleation generally across most amyloids. These findings could unlock structure-based drug design of therapeutics that aim to halt amyloid disorders by inhibiting secondary nucleation sites.","lang":"eng"}],"date_created":"2026-03-01T23:01:38Z","file":[{"file_name":"2026_NatureComm_Hu.pdf","date_created":"2026-03-02T09:34:18Z","content_type":"application/pdf","success":1,"relation":"main_file","creator":"dernst","access_level":"open_access","date_updated":"2026-03-02T09:34:18Z","checksum":"fa2b55b3a0d8978de7d2d061c7ad8779","file_size":4821073,"file_id":"21377"}],"oa":1,"type":"journal_article"},{"type":"journal_article","abstract":[{"lang":"eng","text":"There may be a newly identified early phase of supermassive black hole growth"}],"date_created":"2026-03-01T23:01:39Z","quality_controlled":"1","status":"public","corr_author":"1","article_type":"comment","project":[{"name":"Young galaxies as tracers and agents of cosmic reionization","_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224"}],"author":[{"first_name":"Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720"}],"year":"2026","doi":"10.1126/science.adz8603","day":"19","scopus_import":"1","page":"767-768","month":"02","title":"Black holes disguised as little red dots","acknowledgement":"The author acknowledges the support from the European Union (European Research Council, AGENTS, 101076224).","publication":"Science","intvolume":" 391","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","date_published":"2026-02-19T00:00:00Z","volume":391,"publication_status":"published","publisher":"AAAS","OA_type":"closed access","language":[{"iso":"eng"}],"external_id":{"pmid":["41712710"]},"publication_identifier":{"eissn":["1095-9203"]},"citation":{"apa":"Matthee, J. J. (2026). Black holes disguised as little red dots. Science. AAAS. https://doi.org/10.1126/science.adz8603","mla":"Matthee, Jorryt J. “Black Holes Disguised as Little Red Dots.” Science, vol. 391, no. 6787, AAAS, 2026, pp. 767–68, doi:10.1126/science.adz8603.","ama":"Matthee JJ. Black holes disguised as little red dots. Science. 2026;391(6787):767-768. doi:10.1126/science.adz8603","ista":"Matthee JJ. 2026. Black holes disguised as little red dots. Science. 391(6787), 767–768.","short":"J.J. Matthee, Science 391 (2026) 767–768.","chicago":"Matthee, Jorryt J. “Black Holes Disguised as Little Red Dots.” Science. AAAS, 2026. https://doi.org/10.1126/science.adz8603.","ieee":"J. J. Matthee, “Black holes disguised as little red dots,” Science, vol. 391, no. 6787. AAAS, pp. 767–768, 2026."},"department":[{"_id":"JoMa"}],"pmid":1,"date_updated":"2026-03-02T09:15:45Z","article_processing_charge":"No","_id":"21371","issue":"6787"},{"status":"public","arxiv":1,"quality_controlled":"1","corr_author":"1","type":"journal_article","file":[{"checksum":"172720f1f0c5c9d06a282e52023a0030","file_size":16789781,"file_id":"21376","relation":"main_file","access_level":"open_access","creator":"dernst","date_updated":"2026-03-02T09:24:44Z","file_name":"2026_JPhysPhotonics_Volpe.pdf","content_type":"application/pdf","date_created":"2026-03-02T09:24:44Z","success":1}],"oa":1,"date_created":"2026-03-01T23:01:39Z","abstract":[{"lang":"eng","text":"Cold atom experiments show that a mobile impurity particle immersed in a weakly interacting Bose-Einstein condensate forms a well-defined quasiparticle (Bose polaron) for weak to moderate impurity-boson interaction strengths, whereas a significant line broadening is consistently observed for strong interactions. Motivated by this, we introduce a phenomenological theory based on the assumption that the most relevant states are characterized by the impurity correlated with at most one boson, since they have the largest overlap with the uncorrelated states to which the most common experimental probes couple. These experimentally relevant states can, however, decay to lower energy states characterized by correlations involving multiple bosons, and we model this using a minimal variational wave function combined with a complex impurity-boson interaction strength. We first motivate this approach by comparing to a more elaborate theory that includes correlations with up to two bosons. Our phenomenological model is shown to recover the main results of two recent experiments probing both the spectral and the nonequilibrium properties of the Bose polaron. Our work offers an intuitive framework for analyzing experimental data and highlights the importance of understanding the complicated problem of the Bose polaron decay in a many-body setting."}],"title":"Phenomenological model of decaying Bose polarons","month":"02","ddc":["530"],"PlanS_conform":"1","article_type":"letter_note","article_number":"L012034","day":"06","DOAJ_listed":"1","scopus_import":"1","author":[{"first_name":"Ragheed","last_name":"Al Hyder","full_name":"Al Hyder, Ragheed","id":"d1c405be-ae15-11ed-8510-ccf53278162e"},{"full_name":"Bruun, G. M.","last_name":"Bruun","first_name":"G. M."},{"last_name":"Pohl","first_name":"T.","full_name":"Pohl, T."},{"full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","first_name":"Mikhail","last_name":"Lemeshko"},{"id":"37D278BC-F248-11E8-B48F-1D18A9856A87","full_name":"Volosniev, Artem","orcid":"0000-0003-0393-5525","last_name":"Volosniev","first_name":"Artem"}],"project":[{"grant_number":"801770","call_identifier":"H2020","_id":"2688CF98-B435-11E9-9278-68D0E5697425","name":"Angulon: physics and applications of a new quasiparticle"},{"name":"Polarons in Lead Halide Perovskites","_id":"8fa7db46-16d5-11f0-9cad-917600954daf","grant_number":"12078"}],"doi":"10.1103/16dk-5dgx","year":"2026","date_published":"2026-02-06T00:00:00Z","volume":8,"ec_funded":1,"oa_version":"Published Version","publication_status":"published","publisher":"American Physical Society","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"We thank Georgios Koutentakis, Frédéric Chevy, Hussam Al Daas, and Richard Schmidt for fruitful discussions; Jan Arlt for sharing their experimental data and many fruitful discussions; and Christoph Eigen for sharing their experimental data and inspiring discussions. R.A., T.P., and G.M.B. have been supported in part by the Danish National Research Foundation through the Center of Excellence “CCQ” (Grant Agreement No. DNRF156) and the Independent Research Fund Denmark–Natural Sciences via Grant No. DFF-8021-00233B. R.A., A.G.V., and M.L. acknowledge support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). R.A. received funding from the Austrian Academy of Science ÖAW Grant No. PR1029OEAW03.","file_date_updated":"2026-03-02T09:24:44Z","intvolume":" 8","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Physical Review Research","_id":"21373","date_updated":"2026-03-02T09:27:26Z","article_processing_charge":"No","OA_place":"publisher","OA_type":"gold","language":[{"iso":"eng"}],"has_accepted_license":"1","citation":{"chicago":"Al Hyder, Ragheed, G. M. Bruun, T. Pohl, Mikhail Lemeshko, and Artem Volosniev. “Phenomenological Model of Decaying Bose Polarons.” Physical Review Research. American Physical Society, 2026. https://doi.org/10.1103/16dk-5dgx.","ieee":"R. Al Hyder, G. M. Bruun, T. Pohl, M. Lemeshko, and A. Volosniev, “Phenomenological model of decaying Bose polarons,” Physical Review Research, vol. 8. American Physical Society, 2026.","apa":"Al Hyder, R., Bruun, G. M., Pohl, T., Lemeshko, M., & Volosniev, A. (2026). Phenomenological model of decaying Bose polarons. Physical Review Research. American Physical Society. https://doi.org/10.1103/16dk-5dgx","mla":"Al Hyder, Ragheed, et al. “Phenomenological Model of Decaying Bose Polarons.” Physical Review Research, vol. 8, L012034, American Physical Society, 2026, doi:10.1103/16dk-5dgx.","ama":"Al Hyder R, Bruun GM, Pohl T, Lemeshko M, Volosniev A. Phenomenological model of decaying Bose polarons. Physical Review Research. 2026;8. doi:10.1103/16dk-5dgx","short":"R. Al Hyder, G.M. Bruun, T. Pohl, M. Lemeshko, A. Volosniev, Physical Review Research 8 (2026).","ista":"Al Hyder R, Bruun GM, Pohl T, Lemeshko M, Volosniev A. 2026. Phenomenological model of decaying Bose polarons. Physical Review Research. 8, L012034."},"publication_identifier":{"issn":["2643-1564"]},"department":[{"_id":"MiLe"}],"external_id":{"arxiv":["2507.04143"]}},{"volume":16448,"date_published":"2026-02-13T00:00:00Z","oa_version":"Preprint","publication_status":"published","publisher":"Springer Nature","alternative_title":["LNCS"],"acknowledgement":"We thank the organizers of the HOMONOLO 2024 workshop in Nová Louka, Czech Republic, for the fruitful atmosphere where the research on this project was initiated.\r\n\r\nT. Antić, A. Džuklevski, J. Kratochvíl and M. Saumell received funding from GAČR grant 23–04949X, T.A and A.Dž were additionally supported by GAUK grant SVV–2025–260822. G. Liotta was supported in part by MUR of Italy, PRIN Project no. 2022TS4Y3N – EXPAND and PON Project ARS01_00540. J. Fiala was in part supported by GAČR grant 25-16847S.","conference":{"end_date":"2026-02-13","location":"Krakow, Poland","name":"SOFSEM: Conference on Current Trends in Theory and Practice of Computer Science","start_date":"2026-02-09"},"intvolume":" 16448","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"51st International Conference on Current Trends in Theory and Practice of Computer Science","_id":"21374","date_updated":"2026-03-02T08:49:20Z","article_processing_charge":"No","OA_type":"green","language":[{"iso":"eng"}],"OA_place":"repository","citation":{"ama":"Antić T, Džuklevski A, Fiala J, et al. Edge-constrained Hamiltonian paths on a point set. In: 51st International Conference on Current Trends in Theory and Practice of Computer Science. Vol 16448. Springer Nature; 2026:532-546. doi:10.1007/978-3-032-17801-5_39","mla":"Antić, Todor, et al. “Edge-Constrained Hamiltonian Paths on a Point Set.” 51st International Conference on Current Trends in Theory and Practice of Computer Science, vol. 16448, Springer Nature, 2026, pp. 532–46, doi:10.1007/978-3-032-17801-5_39.","ista":"Antić T, Džuklevski A, Fiala J, Kratochvíl J, Liotta G, Saghafian M, Saumell M, Zink J. 2026. Edge-constrained Hamiltonian paths on a point set. 51st International Conference on Current Trends in Theory and Practice of Computer Science. SOFSEM: Conference on Current Trends in Theory and Practice of Computer Science, LNCS, vol. 16448, 532–546.","short":"T. Antić, A. Džuklevski, J. Fiala, J. Kratochvíl, G. Liotta, M. Saghafian, M. Saumell, J. Zink, in:, 51st International Conference on Current Trends in Theory and Practice of Computer Science, Springer Nature, 2026, pp. 532–546.","apa":"Antić, T., Džuklevski, A., Fiala, J., Kratochvíl, J., Liotta, G., Saghafian, M., … Zink, J. (2026). Edge-constrained Hamiltonian paths on a point set. In 51st International Conference on Current Trends in Theory and Practice of Computer Science (Vol. 16448, pp. 532–546). Krakow, Poland: Springer Nature. https://doi.org/10.1007/978-3-032-17801-5_39","chicago":"Antić, Todor, Aleksa Džuklevski, Jiří Fiala, Jan Kratochvíl, Giuseppe Liotta, Morteza Saghafian, Maria Saumell, and Johannes Zink. “Edge-Constrained Hamiltonian Paths on a Point Set.” In 51st International Conference on Current Trends in Theory and Practice of Computer Science, 16448:532–46. Springer Nature, 2026. https://doi.org/10.1007/978-3-032-17801-5_39.","ieee":"T. Antić et al., “Edge-constrained Hamiltonian paths on a point set,” in 51st International Conference on Current Trends in Theory and Practice of Computer Science, Krakow, Poland, 2026, vol. 16448, pp. 532–546."},"publication_identifier":{"eissn":["1611-3349"],"issn":["0302-9743"],"isbn":["9783032178008"]},"department":[{"_id":"HeEd"}],"external_id":{"arxiv":["2511.22526"]},"status":"public","quality_controlled":"1","arxiv":1,"type":"conference","oa":1,"date_created":"2026-03-01T23:01:40Z","abstract":[{"text":"Let . S be a set of distinct points in general position in the\r\nEuclidean plane. A plane Hamiltonian path on . S is a crossing-free geometric path such that every point of .S is a vertex of the path. It is\r\nknown that, if. S is sufficiently large, there exist three edge-disjoint plane\r\nHamiltonian paths on . S. In this paper we study an edge-constrained\r\nversion of the problem of finding Hamiltonian paths on a point set. We\r\nfirst consider the problem of finding a single plane Hamiltonian path . π\r\nwith endpoints .s, t ∈ S and constraints given by a segment . ab, where\r\n.a, b ∈ S. We consider the following scenarios: (i) .ab ∈ π; (ii) .ab π. We\r\ncharacterize those quintuples . S, a, b, s, t for which . π exists. Secondly,\r\nwe consider the problem of finding two plane Hamiltonian paths . π1, π2\r\non a set . S with constraints given by a segment . ab, where .a, b ∈ S. We\r\nconsider the following scenarios: (i) .π1 and .π2 share no edges and .ab is\r\nan edge of . π1; (ii) .π1 and .π2 share no edges and none of them includes\r\n.ab as an edge; (iii) both .π1 and .π2 include .ab as an edge and share no\r\nother edges. In all cases, we characterize those triples . S, a, b for which\r\n.π1 and .π2 exist.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2511.22526"}],"title":"Edge-constrained Hamiltonian paths on a point set","month":"02","day":"13","scopus_import":"1","page":"532-546","author":[{"first_name":"Todor","last_name":"Antić","full_name":"Antić, Todor"},{"full_name":"Džuklevski, Aleksa","first_name":"Aleksa","last_name":"Džuklevski"},{"last_name":"Fiala","first_name":"Jiří","full_name":"Fiala, Jiří"},{"full_name":"Kratochvíl, Jan","last_name":"Kratochvíl","first_name":"Jan"},{"first_name":"Giuseppe","last_name":"Liotta","full_name":"Liotta, Giuseppe"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","full_name":"Saghafian, Morteza","last_name":"Saghafian","first_name":"Morteza"},{"last_name":"Saumell","first_name":"Maria","full_name":"Saumell, Maria"},{"last_name":"Zink","first_name":"Johannes","full_name":"Zink, Johannes"}],"doi":"10.1007/978-3-032-17801-5_39","year":"2026"},{"oa_version":"Published Version","volume":8,"date_published":"2026-02-11T00:00:00Z","publisher":"Springer Nature","publication_status":"published","acknowledgement":"We thank all members of the laboratory of J.d.J.-S. for insightful discussions and comments. We thank S. Perez for technical assistance. This work was made possible by the Paris Brain Institute Diane Barriere Chair in Synaptic Bioenergetics awarded to J.d.J.-S., who is also supported by an ERC Starting Grant (SynaptoEnergy, European Research Council; ERC-StG-852873), 2019 ATIP-Avenir Grant (CNRS, Inserm), a Big Brain Theory Grant (ICM Foundation) and a Kavli Exploratory Award (Kavli Foundation). This work was also supported by an ERC Advanced Grant (EnergyMeMo; ERC-AdG-741550) to T.P. and grants from the Agence Nationale de la Recherche to P.Y.P. (ANR-20-CE92-0047-01), T.P. (ANR-23-CE16-0029-01), A.P. and J.d.J.-S. (ANR-22-CE16-0020) and J.d.J.-S. (ANR-24-CE16-0221). T.P., P.Y.P. and J.d.J.-S. are permanent CNRS researchers. A.P. is a permanent ESPCI associate professor. T.C. was funded by the French Ministry of Research and the Fondation pour la Recherche Médicale. V.R. was funded by the Max Planck Society, the Chan Zuckerberg Initiative DAF, an advised fund of the Silicon Valley Community Foundation grant number 2024-349543 and the NIH Director’s New Innovator Award (DP2 MH140148). A.B.-G. and C.R.-D. received funding from an ERC Starting Grant (HighMemory; ERC-StG-948217), the Ministry of Economy and Competitiveness (PID2021-122795OB-I00) and the Departament d’Economia i Coneixement de la Generalitat de Catalunya (SGR 00022). T.P.V. was funded by the Wellcome Trust and a Royal Society Sir Henry Dale Research Fellowship (WT100000) and a Wellcome Trust Senior Research Fellowship (214316/Z/18/Z). K.G. was supported by the DIM C-BRAINS, funded by the Conseil Régional d’Ile-de-France. The contributions of H.F. and E.R.S. were supported by the Howard Hughes Medical Institute. The PHENO-ICMice animal Core at ICM is supported by two ‘Investissements d’avenir’ (ANR-10- IAIHU-06 and ANR-11-INBS-0011-NeurATRIS) and the Fondation pour la Recherche Médicale.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Nature Metabolism","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-03-02T15:21:27Z","intvolume":" 8","article_processing_charge":"Yes (in subscription journal)","date_updated":"2026-03-02T15:23:10Z","_id":"21378","issue":"2","has_accepted_license":"1","OA_place":"publisher","language":[{"iso":"eng"}],"OA_type":"hybrid","external_id":{"pmid":["41673453"]},"department":[{"_id":"TiVo"}],"pmid":1,"citation":{"ieee":"A. Amrapali Vishwanath et al., “Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species,” Nature Metabolism, vol. 8, no. 2. Springer Nature, pp. 467–488, 2026.","chicago":"Amrapali Vishwanath, Anjali, Typhaine Comyn, Rodrigo G. Mira, Claire Brossier, Carlos Pascual-Caro, Maya Faour, Kahina Boumendil, et al. “Mitochondrial Ca2+ Efflux Controls Neuronal Metabolism and Long-Term Memory across Species.” Nature Metabolism. Springer Nature, 2026. https://doi.org/10.1038/s42255-026-01451-w.","ista":"Amrapali Vishwanath A, Comyn T, Mira RG, Brossier C, Pascual-Caro C, Faour M, Boumendil K, Chintaluri C, Ramon-Duaso C, Fan R, Ghosh K, Farrants H, Berwick J-P, Sivakumar R, Lopez-Manzaneda M, Schreiter ER, Preat T, Vogels TP, Rangaraju V, Busquets-Garcia A, Plaçais P-Y, Pavlowsky A, de Juan-Sanz J. 2026. Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species. Nature Metabolism. 8(2), 467–488.","short":"A. Amrapali Vishwanath, T. Comyn, R.G. Mira, C. Brossier, C. Pascual-Caro, M. Faour, K. Boumendil, C. Chintaluri, C. Ramon-Duaso, R. Fan, K. Ghosh, H. Farrants, J.-P. Berwick, R. Sivakumar, M. Lopez-Manzaneda, E.R. Schreiter, T. Preat, T.P. Vogels, V. Rangaraju, A. Busquets-Garcia, P.-Y. Plaçais, A. Pavlowsky, J. de Juan-Sanz, Nature Metabolism 8 (2026) 467–488.","mla":"Amrapali Vishwanath, Anjali, et al. “Mitochondrial Ca2+ Efflux Controls Neuronal Metabolism and Long-Term Memory across Species.” Nature Metabolism, vol. 8, no. 2, Springer Nature, 2026, pp. 467–88, doi:10.1038/s42255-026-01451-w.","ama":"Amrapali Vishwanath A, Comyn T, Mira RG, et al. Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species. Nature Metabolism. 2026;8(2):467-488. doi:10.1038/s42255-026-01451-w","apa":"Amrapali Vishwanath, A., Comyn, T., Mira, R. G., Brossier, C., Pascual-Caro, C., Faour, M., … de Juan-Sanz, J. (2026). Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species. Nature Metabolism. Springer Nature. https://doi.org/10.1038/s42255-026-01451-w"},"publication_identifier":{"eissn":["2522-5812"]},"quality_controlled":"1","status":"public","oa":1,"file":[{"file_size":5326608,"checksum":"365932a599d05bc9ce8a57204e7a1465","file_id":"21392","relation":"main_file","date_updated":"2026-03-02T15:21:27Z","access_level":"open_access","creator":"dernst","content_type":"application/pdf","date_created":"2026-03-02T15:21:27Z","file_name":"2026_NatureMetab_AmrapaliVishwanath.pdf","success":1}],"type":"journal_article","abstract":[{"text":"From insects to mammals, essential brain functions, such as forming long-term memories (LTMs), increase metabolic activity in stimulated neurons to meet the energetic demand associated with brain activation. However, while impairing neuronal metabolism limits brain performance, whether expanding the metabolic capacity of neurons boosts brain function remains poorly understood. Here, we show that LTM formation of flies and mice can be enhanced by increasing mitochondrial metabolism in central memory circuits. By knocking down the mitochondrial Ca2+ exporter Letm1, we favour Ca2+ retention in the mitochondrial matrix of neurons due to reduction of mitochondrial H+/Ca2+ exchange. The resulting increase in mitochondrial Ca2+ over-activates mitochondrial metabolism in neurons of central memory circuits, leading to improved LTM storage in training paradigms in which wild-type counterparts of both species fail to remember. Our findings unveil an evolutionarily conserved mechanism that controls mitochondrial metabolism in neurons and indicate its involvement in shaping higher brain functions, such as LTM.","lang":"eng"}],"date_created":"2026-03-02T10:04:49Z","month":"02","title":"Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species","PlanS_conform":"1","ddc":["570"],"article_type":"original","year":"2026","doi":"10.1038/s42255-026-01451-w","author":[{"full_name":"Amrapali Vishwanath, Anjali","first_name":"Anjali","last_name":"Amrapali Vishwanath"},{"full_name":"Comyn, Typhaine","first_name":"Typhaine","last_name":"Comyn"},{"full_name":"Mira, Rodrigo G.","first_name":"Rodrigo G.","last_name":"Mira"},{"last_name":"Brossier","first_name":"Claire","full_name":"Brossier, Claire"},{"last_name":"Pascual-Caro","first_name":"Carlos","full_name":"Pascual-Caro, Carlos"},{"first_name":"Maya","last_name":"Faour","full_name":"Faour, Maya"},{"full_name":"Boumendil, Kahina","first_name":"Kahina","last_name":"Boumendil"},{"id":"BA06AFEE-A4BA-11EA-AE5C-14673DDC885E","full_name":"Chintaluri, Chaitanya","first_name":"Chaitanya","last_name":"Chintaluri","orcid":"0000-0003-4252-1608"},{"first_name":"Carla","last_name":"Ramon-Duaso","full_name":"Ramon-Duaso, Carla"},{"last_name":"Fan","first_name":"Ruolin","full_name":"Fan, Ruolin"},{"full_name":"Ghosh, Kishalay","first_name":"Kishalay","last_name":"Ghosh"},{"full_name":"Farrants, Helen","first_name":"Helen","last_name":"Farrants"},{"last_name":"Berwick","first_name":"Jean-Paul","full_name":"Berwick, Jean-Paul"},{"last_name":"Sivakumar","first_name":"Riya","full_name":"Sivakumar, Riya"},{"full_name":"Lopez-Manzaneda, Mario","last_name":"Lopez-Manzaneda","first_name":"Mario"},{"full_name":"Schreiter, Eric R.","last_name":"Schreiter","first_name":"Eric R."},{"full_name":"Preat, Thomas","first_name":"Thomas","last_name":"Preat"},{"last_name":"Vogels","first_name":"Tim P","orcid":"0000-0003-3295-6181","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","full_name":"Vogels, Tim P"},{"full_name":"Rangaraju, Vidhya","first_name":"Vidhya","last_name":"Rangaraju"},{"full_name":"Busquets-Garcia, Arnau","last_name":"Busquets-Garcia","first_name":"Arnau"},{"last_name":"Plaçais","first_name":"Pierre-Yves","full_name":"Plaçais, Pierre-Yves"},{"full_name":"Pavlowsky, Alice","last_name":"Pavlowsky","first_name":"Alice"},{"last_name":"de Juan-Sanz","first_name":"Jaime","full_name":"de Juan-Sanz, Jaime"}],"project":[{"_id":"c084a126-5a5b-11eb-8a69-d75314a70a87","grant_number":"214316/Z/18/Z","name":"What’s in a memory? Spatiotemporal dynamics in strongly coupled recurrent neuronal networks."}],"page":"467-488","scopus_import":"1","day":"11"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Probability Theory and Related Fields","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"FO and CW thank Ron Peled for insightful discussions on the white-noise multi-dimensional case in the Fall of 2023. CW thanks Barbara Dembin for the discussion during a workshop in Spring 2025. The work was done while the authors were affiliated with the Max Planck Institute for Mathematics in the Sciences; CW thanks the MPI for the support and warm hospitality. Open access funding provided by Institute of Science and Technology (IST Austria).","publication_status":"epub_ahead","publisher":"Springer Nature","date_published":"2026-02-14T00:00:00Z","oa_version":"Published Version","publication_identifier":{"eissn":["1432-2064"],"issn":["0178-8051"]},"citation":{"ieee":"F. Otto, M. Palmieri, and C. Wagner, “On minimizing curves in a Brownian potential,” Probability Theory and Related Fields. Springer Nature, 2026.","chicago":"Otto, Felix, Matteo Palmieri, and Christian Wagner. “On Minimizing Curves in a Brownian Potential.” Probability Theory and Related Fields. Springer Nature, 2026. https://doi.org/10.1007/s00440-026-01468-y.","apa":"Otto, F., Palmieri, M., & Wagner, C. (2026). On minimizing curves in a Brownian potential. Probability Theory and Related Fields. Springer Nature. https://doi.org/10.1007/s00440-026-01468-y","ista":"Otto F, Palmieri M, Wagner C. 2026. On minimizing curves in a Brownian potential. Probability Theory and Related Fields.","short":"F. Otto, M. Palmieri, C. Wagner, Probability Theory and Related Fields (2026).","ama":"Otto F, Palmieri M, Wagner C. On minimizing curves in a Brownian potential. Probability Theory and Related Fields. 2026. doi:10.1007/s00440-026-01468-y","mla":"Otto, Felix, et al. “On Minimizing Curves in a Brownian Potential.” Probability Theory and Related Fields, Springer Nature, 2026, doi:10.1007/s00440-026-01468-y."},"department":[{"_id":"JuFi"}],"OA_place":"publisher","OA_type":"hybrid","language":[{"iso":"eng"}],"has_accepted_license":"1","_id":"21379","date_updated":"2026-03-02T15:15:13Z","article_processing_charge":"Yes (via OA deal)","date_created":"2026-03-02T10:05:23Z","abstract":[{"lang":"eng","text":"We study a (1 + 1)-dimensional semi-discrete random variational problem that can be interpreted as the geometrically linearized version of the critical 2-dimensional random field Ising model. The scaling of the correlation length of the latter was recently characterized in Probab. Duke Math. J. 172(9), 1781–1811 (2023) and arXiv:2011.08768v3, (2022); our analysis is reminiscent of the multi-scale approach of the latter work and of Combinatorica 9, 161–187 (1989) . We show that at every dyadic scale from the system size down to the lattice spacing the minimizer contains at most order-one Dirichlet energy per unit length. We also establish a quenched homogenization result in the sense that the leading order of the minimal energy becomes deterministic as the ratio system size / lattice spacing diverges. To this purpose we adapt arguments from arXiv:2401.06768, (2024) on the (d + 1)-dimensional version our the model, with a Brownian replacing the white noise potential, to obtain the initial large-scale bounds. Based on our estimate of the (p = 3)-Dirichlet energy, we give an informal justification of the geometric linearization. Our bounds, which are oblivious to the microscopic cut-off scale provided by the lattice spacing, yield tightness of the law of minimizers in the space of continuous functions as the lattice spacing is sent to zero."}],"main_file_link":[{"url":"https://doi.org/10.1007/s00440-026-01468-y","open_access":"1"}],"type":"journal_article","oa":1,"corr_author":"1","status":"public","quality_controlled":"1","day":"14","scopus_import":"1","author":[{"full_name":"Otto, Felix","first_name":"Felix","last_name":"Otto"},{"last_name":"Palmieri","first_name":"Matteo","full_name":"Palmieri, Matteo"},{"last_name":"Wagner","first_name":"Christian","id":"bf0c729b-2619-11f0-8024-9d69bb2b8b20","full_name":"Wagner, Christian"}],"year":"2026","doi":"10.1007/s00440-026-01468-y","article_type":"original","ddc":["510"],"title":"On minimizing curves in a Brownian potential","month":"02"},{"acknowledgement":"We thank the referee for several helpful suggestions. AGA, MGO and IM acknowledge financial support from the Severo Ochoa grant CEX2021-001131-S, funded by MICIU/AEI/10.13039/501100011033. AGA also acknowledges FPI support under grant code CEX2021-001131-S20-7. Both AGA and MGO acknowledge support from the research grant\r\nPID2022-136598NB-C32 (“Estallidos8”). MGO also acknowledges the support by the project ref. AST22_00001_Subp_11 funded from the EU – NextGenerationEU. RA acknowledges support from PID2023-147386NB-I00 funded by MICIU/AEI/10.13039/501100011033 and ERDF/EU. IM acknowledges support from PID2022-140871NB-C21 funded by MICIU/AEI/10.13039/501100011033 and FEDER/UE. RGD acknowledge financial support from the project PID2022-141755NB-I00, and the Severo Ochoa grant CEX2021-001131-S funded\r\nby MICIU/AEI/ 10.13039/501100011033. JAFO and AE acknowledge support from the Spanish Ministry of Science and Innovation and the EU–NextGenerationEU through the RRF project ICTS-MRR-2021-03-CEFCA. AHC and ALC acknowledge support from MCIN/AEI/10.13039/501100011033, “ERDF A way of making Europe”, and “EU NextGenerationEU/PRTR” through PID2021-124918NB-C44 and CNS2023-145339, as well as from the RRF project ICTS-MRR-2021-03-CEFCA ALC and RPT acknowledge the financial\r\nsupport from the European Union – NextGenerationEU through the RRF program Planes Complementarios con las CCAA de Astrofísica y Física de Altas Energías – LA4. I.B. acknowledges support from the EU Horizon 2020 programme (Marie Sklodowska-Curie Grant 101059532) and the Franziska Seidl Funding Program, University of Vienna. This paper has gone through internal‘ review by the J-PAS collaboration. Based on observations made with the\r\nJST/T250 telescope and JPCam at the Observatorio Astrofísico de Javalambre (OAJ), in Teruel, owned, managed, and operated by the Centro de Estudios de Física del Cosmos de Aragón (CEFCA). We acknowledge the OAJ Data Processing and Archiving Unit (UPAD) for reducing and calibrating the OAJ data used in this work. Funding for the J-PAS Project has been provided by the Governments of Spain and Aragón through the Fondo de Inversiones de Teruel; the Aragonese Government through the Research Groups E96, E103, E16_17R, E16_20R, and E16_23R; the Spanish Ministry of Science and Innovation (MCIN/AEI/10.13039/501100011033 y FEDER, Una manera de hacer Europa) with grants PID2021-124918NB-C41, PID2021-124918NB-C42, PID2021-124918NA-C43, and PID2021-124918NB-C44; the Spanish Ministry\r\nof Science, Innovation and Universities (MCIU/AEI/FEDER, UE) with grants\r\nPGC2018-097585-B-C21 and PGC2018-097585-B-C22; the Spanish Ministry of Economy and Competitiveness (MINECO) under AYA2015-66211-C2-1-P, AYA2015-66211-C2-2, and AYA2012-30789; and European FEDER funding (FCDD10-4E-867, FCDD13-4E-2685).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Astronomy & Astrophysics","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-03-02T14:51:57Z","intvolume":" 706","oa_version":"Published Version","volume":706,"date_published":"2026-02-01T00:00:00Z","publisher":"EDP Sciences","publication_status":"published","has_accepted_license":"1","OA_type":"diamond","language":[{"iso":"eng"}],"OA_place":"publisher","external_id":{"arxiv":["2512.08484"]},"department":[{"_id":"JoMa"}],"citation":{"chicago":"Giménez-Alcázar, A., R. Amorín, J. M. Vílchez, A. Hernán-Caballero, M. González-Otero, A. Arroyo-Polonio, J. Iglesias-Páramo, et al. “J-PAS: First Identification, Physical Properties, and Ionization Efficiency of Extreme Emission Line Galaxies.” Astronomy & Astrophysics. EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202557358.","ieee":"A. Giménez-Alcázar et al., “J-PAS: First identification, physical properties, and ionization efficiency of extreme emission line galaxies,” Astronomy & Astrophysics, vol. 706. EDP Sciences, 2026.","apa":"Giménez-Alcázar, A., Amorín, R., Vílchez, J. M., Hernán-Caballero, A., González-Otero, M., Arroyo-Polonio, A., … Vázquez Ramió, H. (2026). J-PAS: First identification, physical properties, and ionization efficiency of extreme emission line galaxies. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202557358","ama":"Giménez-Alcázar A, Amorín R, Vílchez JM, et al. J-PAS: First identification, physical properties, and ionization efficiency of extreme emission line galaxies. Astronomy & Astrophysics. 2026;706. doi:10.1051/0004-6361/202557358","mla":"Giménez-Alcázar, A., et al. “J-PAS: First Identification, Physical Properties, and Ionization Efficiency of Extreme Emission Line Galaxies.” Astronomy & Astrophysics, vol. 706, A261, EDP Sciences, 2026, doi:10.1051/0004-6361/202557358.","short":"A. Giménez-Alcázar, R. Amorín, J.M. Vílchez, A. Hernán-Caballero, M. González-Otero, A. Arroyo-Polonio, J. Iglesias-Páramo, A. Lumbreras-Calle, J.A. Fernández-Ontiveros, C. López-Sanjuan, L. Bonatto, R.M. González Delgado, C. Kehrig, A. Torralba Torregrosa, P.T. Rahna, Y. Jiménez-Teja, I. Márquez, I. Breda, A. Álvarez-Candal, R. Abramo, J. Alcaniz, N. Benitez, S. Bonoli, S. Carneiro, J. Cenarro, D. Cristóbal-Hornillos, R. Dupke, A. Ederoclite, C. Hernández-Monteagudo, A. Marín-Franch, C. Mendes de Oliveira, M. Moles, L. Sodré, K. Taylor, J. Varela, H. Vázquez Ramió, Astronomy & Astrophysics 706 (2026).","ista":"Giménez-Alcázar A, Amorín R, Vílchez JM, Hernán-Caballero A, González-Otero M, Arroyo-Polonio A, Iglesias-Páramo J, Lumbreras-Calle A, Fernández-Ontiveros JA, López-Sanjuan C, Bonatto L, González Delgado RM, Kehrig C, Torralba Torregrosa A, Rahna PT, Jiménez-Teja Y, Márquez I, Breda I, Álvarez-Candal A, Abramo R, Alcaniz J, Benitez N, Bonoli S, Carneiro S, Cenarro J, Cristóbal-Hornillos D, Dupke R, Ederoclite A, Hernández-Monteagudo C, Marín-Franch A, Mendes de Oliveira C, Moles M, Sodré L, Taylor K, Varela J, Vázquez Ramió H. 2026. J-PAS: First identification, physical properties, and ionization efficiency of extreme emission line galaxies. Astronomy & Astrophysics. 706, A261."},"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"article_processing_charge":"No","date_updated":"2026-03-02T15:10:27Z","_id":"21380","oa":1,"file":[{"file_name":"2026_AstronomyAstrophysics_GimenezAlcazar.pdf","content_type":"application/pdf","date_created":"2026-03-02T14:51:57Z","success":1,"checksum":"cd25a05386ab5638ae5baf8add0ecbee","file_size":1813456,"file_id":"21391","relation":"main_file","access_level":"open_access","creator":"dernst","date_updated":"2026-03-02T14:51:57Z"}],"type":"journal_article","abstract":[{"text":"Context. Extreme emission line galaxies (EELGs) are believed to significantly contribute to the star formation activity and mass assembly in galaxies. EELGs likely also play a leading role in the cosmic re-ionization as their interstellar medium may allow a significant fraction of their ionizing photons to escape (> 5%). Finding low-redshift analogues of these high-z galaxies is therefore essential to characterizing the physical conditions in the interstellar medium of these galaxies and understanding the processes that re-ionized the Universe.\r\n\r\nAims. We aimed to develop a robust and efficient method for the photometric identification of EELGs using the J-PAS survey. J-PAS will cover approximately 8500 deg2 of the sky with 54 narrow-band filters in the optical range plus i-SDSS, enabling detailed studies of the physical properties of these galaxies. In this work we focused on an initial subset of the survey: a 30 square degree area with complete observations in all bands.\r\n\r\nMethods. We combine equivalent width (EW) measurements from J-PAS narrow-band photometry with artificial intelligence techniques to identify galaxies with emission lines exceeding 300 Å. We validated our selection using spectroscopic data from DESI DR1 and characterized the selected sample through spectral energy distribution fitting with CIGALE.\r\n\r\nResults. We identify 917 EELGs up to z = 0.8 over 30 deg2, achieving a purity of 95% and a completeness of 96% for i-SDSS < 22.5 mag. Importantly, active galactic nucleus contamination was carefully considered and is estimated to be around 5%. Furthermore, a cross-match with DESI yielded 79 counterparts; their redshifts are in excellent agreement with our photometric estimates, thereby confirming the reliability of our redshift determination. In addition, the derived emission line fluxes are in good agreement with spectroscopic measurements. Moreover, the selected sample reveals strong correlations between the ionizing photon production efficiency (ξion) and EW(Hβ), which are consistent with previous observational studies at low and high redshifts and theoretical expectations. Finally, most of the sources surpass the ionizing efficiency threshold required for re-ionization, highlighting their relevance as local analogues of early-Universe galaxies.","lang":"eng"}],"date_created":"2026-03-02T10:06:10Z","quality_controlled":"1","arxiv":1,"status":"public","article_number":"A261","article_type":"original","doi":"10.1051/0004-6361/202557358","year":"2026","author":[{"full_name":"Giménez-Alcázar, A.","last_name":"Giménez-Alcázar","first_name":"A."},{"last_name":"Amorín","first_name":"R.","full_name":"Amorín, R."},{"last_name":"Vílchez","first_name":"J. M.","full_name":"Vílchez, J. M."},{"first_name":"A.","last_name":"Hernán-Caballero","full_name":"Hernán-Caballero, A."},{"full_name":"González-Otero, M.","first_name":"M.","last_name":"González-Otero"},{"full_name":"Arroyo-Polonio, A.","last_name":"Arroyo-Polonio","first_name":"A."},{"last_name":"Iglesias-Páramo","first_name":"J.","full_name":"Iglesias-Páramo, J."},{"full_name":"Lumbreras-Calle, A.","first_name":"A.","last_name":"Lumbreras-Calle"},{"full_name":"Fernández-Ontiveros, J. A.","first_name":"J. A.","last_name":"Fernández-Ontiveros"},{"first_name":"C.","last_name":"López-Sanjuan","full_name":"López-Sanjuan, C."},{"first_name":"L.","last_name":"Bonatto","full_name":"Bonatto, L."},{"full_name":"González Delgado, R. M.","last_name":"González Delgado","first_name":"R. M."},{"full_name":"Kehrig, C.","first_name":"C.","last_name":"Kehrig"},{"full_name":"Torralba Torregrosa, Alberto","id":"018f0249-0e87-11f0-b167-cbce08fbd541","orcid":"0000-0001-5586-6950","last_name":"Torralba Torregrosa","first_name":"Alberto"},{"last_name":"Rahna","first_name":"P. T.","full_name":"Rahna, P. T."},{"full_name":"Jiménez-Teja, Y.","first_name":"Y.","last_name":"Jiménez-Teja"},{"last_name":"Márquez","first_name":"I.","full_name":"Márquez, I."},{"first_name":"I.","last_name":"Breda","full_name":"Breda, I."},{"full_name":"Álvarez-Candal, A.","last_name":"Álvarez-Candal","first_name":"A."},{"full_name":"Abramo, R.","first_name":"R.","last_name":"Abramo"},{"last_name":"Alcaniz","first_name":"J.","full_name":"Alcaniz, J."},{"full_name":"Benitez, N.","first_name":"N.","last_name":"Benitez"},{"full_name":"Bonoli, S.","first_name":"S.","last_name":"Bonoli"},{"full_name":"Carneiro, S.","last_name":"Carneiro","first_name":"S."},{"full_name":"Cenarro, J.","first_name":"J.","last_name":"Cenarro"},{"full_name":"Cristóbal-Hornillos, D.","last_name":"Cristóbal-Hornillos","first_name":"D."},{"first_name":"R.","last_name":"Dupke","full_name":"Dupke, R."},{"full_name":"Ederoclite, A.","first_name":"A.","last_name":"Ederoclite"},{"full_name":"Hernández-Monteagudo, C.","last_name":"Hernández-Monteagudo","first_name":"C."},{"last_name":"Marín-Franch","first_name":"A.","full_name":"Marín-Franch, A."},{"full_name":"Mendes de Oliveira, C.","first_name":"C.","last_name":"Mendes de Oliveira"},{"first_name":"M.","last_name":"Moles","full_name":"Moles, M."},{"first_name":"L.","last_name":"Sodré","full_name":"Sodré, L."},{"first_name":"K.","last_name":"Taylor","full_name":"Taylor, K."},{"first_name":"J.","last_name":"Varela","full_name":"Varela, J."},{"full_name":"Vázquez Ramió, H.","first_name":"H.","last_name":"Vázquez Ramió"}],"scopus_import":"1","DOAJ_listed":"1","day":"01","month":"02","title":"J-PAS: First identification, physical properties, and ionization efficiency of extreme emission line galaxies","ddc":["520"]},{"title":"Long-range electrostatics for machine learning interatomic potentials is easier than we thought","month":"02","article_type":"original","article_number":"060901","day":"14","scopus_import":"1","author":[{"last_name":"Kim","first_name":"Dongjin","full_name":"Kim, Dongjin"},{"id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","full_name":"Cheng, Bingqing","orcid":"0000-0002-3584-9632","first_name":"Bingqing","last_name":"Cheng"}],"doi":"10.1063/5.0316886","year":"2026","status":"public","quality_controlled":"1","arxiv":1,"corr_author":"1","type":"journal_article","oa":1,"date_created":"2026-03-02T10:06:46Z","abstract":[{"text":"The lack of long-range electrostatics is a key limitation of modern machine learning interatomic potentials (MLIPs), hindering reliable applications to interfaces, charge-transfer reactions, polar and ionic materials, and biomolecules. In this Perspective, we distill two design principles behind the Latent Ewald Summation framework, which can capture long-range interactions, charges, and electrical response just by learning from standard energy and force training data: (i) use a Coulomb functional form with environment-dependent charges to capture electrostatic interactions, and (ii) avoid explicit training on ambiguous density functional theory partial charges. When both principles are satisfied, substantial flexibility remains: essentially any short-range MLIP can be augmented; charge equilibration schemes can be added when desired; dipoles and Born effective charges can be inferred or fine-tuned; and charge/spin-state embeddings or tensorial targets can be further incorporated. We also discuss current limitations and open challenges. Together, these minimal, physics-guided design rules suggest that incorporating long-range electrostatics into MLIPs is simpler and perhaps more broadly applicable than is commonly assumed.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2512.18029"}],"_id":"21381","date_updated":"2026-03-02T14:46:24Z","article_processing_charge":"No","issue":"6","OA_place":"repository","language":[{"iso":"eng"}],"OA_type":"free access","citation":{"apa":"Kim, D., & Cheng, B. (2026). Long-range electrostatics for machine learning interatomic potentials is easier than we thought. The Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/5.0316886","short":"D. Kim, B. Cheng, The Journal of Chemical Physics 164 (2026).","ista":"Kim D, Cheng B. 2026. Long-range electrostatics for machine learning interatomic potentials is easier than we thought. The Journal of Chemical Physics. 164(6), 060901.","ama":"Kim D, Cheng B. Long-range electrostatics for machine learning interatomic potentials is easier than we thought. The Journal of Chemical Physics. 2026;164(6). doi:10.1063/5.0316886","mla":"Kim, Dongjin, and Bingqing Cheng. “Long-Range Electrostatics for Machine Learning Interatomic Potentials Is Easier than We Thought.” The Journal of Chemical Physics, vol. 164, no. 6, 060901, AIP Publishing, 2026, doi:10.1063/5.0316886.","ieee":"D. Kim and B. Cheng, “Long-range electrostatics for machine learning interatomic potentials is easier than we thought,” The Journal of Chemical Physics, vol. 164, no. 6. AIP Publishing, 2026.","chicago":"Kim, Dongjin, and Bingqing Cheng. “Long-Range Electrostatics for Machine Learning Interatomic Potentials Is Easier than We Thought.” The Journal of Chemical Physics. AIP Publishing, 2026. https://doi.org/10.1063/5.0316886."},"publication_identifier":{"eissn":["1089-7690"],"issn":["0021-9606"]},"department":[{"_id":"BiCh"}],"external_id":{"arxiv":["2512.18029"]},"volume":164,"date_published":"2026-02-14T00:00:00Z","oa_version":"Preprint","publication_status":"published","publisher":"AIP Publishing","acknowledgement":"B.C. thanks Christoph Dellago for his mentorship and influence. In addition to his seminal contributions to statistical mechanics, Christoph Dellago is an early developer and adopter of machine learning interatomic potentials. B.C. did two exchanges in the groups of Christoph Dellago and Jörg Behler in 2018, with transformative impact on her research directions.\r\n\r\nWe thank Peichen Zhong and Daniel S. King for useful feedback on the manuscript and for the collaborations on the LES method.\r\n\r\nFunding acknowledgment: Research reported in this publication was supported by the National Institute Of General Medical Sciences of the National Institutes of Health under Award No. R35GM159986. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.","intvolume":" 164","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"The Journal of Chemical Physics"},{"scopus_import":"1","day":"01","DOAJ_listed":"1","doi":"10.1126/sciadv.ady1461","year":"2026","author":[{"first_name":"Vidyanand","last_name":"Sasidharan","full_name":"Sasidharan, Vidyanand"},{"first_name":"Laura","last_name":"Ancellotti","full_name":"Ancellotti, Laura"},{"last_name":"Doddihal","first_name":"Viraj","full_name":"Doddihal, Viraj","id":"034e0824-174b-11ef-b32b-9366a0e70d1c"},{"full_name":"Brewster, Carolyn","last_name":"Brewster","first_name":"Carolyn"},{"first_name":"Frederick","last_name":"Mann","full_name":"Mann, Frederick"},{"last_name":"McKinney","first_name":"Mary Cathleen","full_name":"McKinney, Mary Cathleen"},{"first_name":"Joseph","last_name":"Varberg","full_name":"Varberg, Joseph"},{"first_name":"Eric","last_name":"Ross","full_name":"Ross, Eric"},{"full_name":"Deng, Fengyan","first_name":"Fengyan","last_name":"Deng"},{"first_name":"Kexi","last_name":"Yi","full_name":"Yi, Kexi"},{"full_name":"Sánchez Alvarado, Alejandro","last_name":"Sánchez Alvarado","first_name":"Alejandro"}],"article_type":"original","article_number":"eady1461","ddc":["570"],"title":"Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians","month":"02","date_created":"2026-03-02T10:08:07Z","abstract":[{"lang":"eng","text":"Planarian flatworms are known for their remarkable regenerative capacity; however, the precise intercellular communication mechanisms underlying this process remain unsolved. Here, we report the discovery and characterization of abundant extracellular vesicles (EVs) in planarians. Using imaging and molecular analysis, we show conservation of biogenesis, morphology, and protein composition of planarian EVs. Environmental stressors significantly elevate EV release, indicating that planarians dynamically regulate vesicle production. Functionally, planarian EVs mediate intercellular communication by transferring regulatory signals: We find that they shuttle small RNAs that effect systemic RNA interference (RNAi) throughout the organism. Notably, gene knockdown experiments reveal a crucial role for AGO-3, a member of the Argonaute family of proteins, in modulating the association of small interfering RNAs with EVs, linking the intracellular RNAi machinery to EV-based signaling. These findings highlight EVs as pivotal mediators of cell-cell communication in planarians, with broad implications for understanding the coordination of gene regulation and tissue regeneration in animals."}],"type":"journal_article","oa":1,"file":[{"relation":"main_file","date_updated":"2026-03-02T14:19:35Z","creator":"dernst","access_level":"open_access","file_size":2841345,"checksum":"fa9f6dafe3538e2d2872c098e06d1712","file_id":"21389","date_created":"2026-03-02T14:19:35Z","content_type":"application/pdf","file_name":"2026_ScienceAdv_Sasidharan.pdf","success":1}],"status":"public","quality_controlled":"1","department":[{"_id":"CaHe"}],"publication_identifier":{"eissn":["2375-2548"]},"citation":{"ieee":"V. Sasidharan et al., “Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians,” Science Advances, vol. 12, no. 6. American Association for the Advancement of Science, 2026.","chicago":"Sasidharan, Vidyanand, Laura Ancellotti, Viraj Doddihal, Carolyn Brewster, Frederick Mann, Mary Cathleen McKinney, Joseph Varberg, et al. “Extracellular Vesicles Mediate Stem Cell Signaling and Systemic RNAi in Planarians.” Science Advances. American Association for the Advancement of Science, 2026. https://doi.org/10.1126/sciadv.ady1461.","apa":"Sasidharan, V., Ancellotti, L., Doddihal, V., Brewster, C., Mann, F., McKinney, M. C., … Sánchez Alvarado, A. (2026). Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. Science Advances. American Association for the Advancement of Science. https://doi.org/10.1126/sciadv.ady1461","short":"V. Sasidharan, L. Ancellotti, V. Doddihal, C. Brewster, F. Mann, M.C. McKinney, J. Varberg, E. Ross, F. Deng, K. Yi, A. Sánchez Alvarado, Science Advances 12 (2026).","ista":"Sasidharan V, Ancellotti L, Doddihal V, Brewster C, Mann F, McKinney MC, Varberg J, Ross E, Deng F, Yi K, Sánchez Alvarado A. 2026. Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. Science Advances. 12(6), eady1461.","ama":"Sasidharan V, Ancellotti L, Doddihal V, et al. Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians. Science Advances. 2026;12(6). doi:10.1126/sciadv.ady1461","mla":"Sasidharan, Vidyanand, et al. “Extracellular Vesicles Mediate Stem Cell Signaling and Systemic RNAi in Planarians.” Science Advances, vol. 12, no. 6, eady1461, American Association for the Advancement of Science, 2026, doi:10.1126/sciadv.ady1461."},"has_accepted_license":"1","OA_place":"publisher","OA_type":"gold","language":[{"iso":"eng"}],"issue":"6","_id":"21383","article_processing_charge":"Yes","date_updated":"2026-03-02T14:23:22Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-03-02T14:19:35Z","intvolume":" 12","publication":"Science Advances","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"acknowledgement":"We thank all the Sánchez Alvarado lab members for inputs and discussions. We are grateful to the Stowers Aquatics (particularly the Planarian team), Microscopy, and Molecular Biology core facilities for technical contributions and method development; e. n. lissek and A. Fujii from Oni US and S. Wang from the University of Missouri, Kansas city, for assistance with dStORM imaging; and d. Alburty and A. Page from innovaprep for assisting with the ntA. We also thank M. Miller for the illustrations. This work was supported by the hhMi and Stowers institute. ","publisher":"American Association for the Advancement of Science","publication_status":"published","date_published":"2026-02-01T00:00:00Z","volume":12,"oa_version":"Published Version"},{"article_type":"original","article_number":"e1013934","day":"03","DOAJ_listed":"1","scopus_import":"1","author":[{"full_name":"Liu, Jiayi","first_name":"Jiayi","last_name":"Liu"},{"last_name":"Ron","first_name":"Jonathan E.","full_name":"Ron, Jonathan E."},{"first_name":"Giulia","last_name":"Rinaldi","full_name":"Rinaldi, Giulia"},{"full_name":"Williantarra, Ivanna","first_name":"Ivanna","last_name":"Williantarra"},{"full_name":"Georgantzoglou, Antonios","last_name":"Georgantzoglou","first_name":"Antonios"},{"last_name":"de Vries","first_name":"Ingrid","full_name":"de Vries, Ingrid","id":"4C7D837E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6620-9179","last_name":"Sixt","first_name":"Michael K"},{"full_name":"Sarris, Milka","last_name":"Sarris","first_name":"Milka"},{"last_name":"Gov","first_name":"Nir S.","full_name":"Gov, Nir S."}],"project":[{"name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces","grant_number":"101071793","_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd"}],"doi":"10.1371/journal.pcbi.1013934","year":"2026","title":"Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation","month":"02","ddc":["570"],"PlanS_conform":"1","type":"journal_article","file":[{"success":1,"date_created":"2026-03-02T14:11:14Z","content_type":"application/pdf","file_name":"2026_PloSCompBio_.pdf","date_updated":"2026-03-02T14:11:14Z","creator":"dernst","access_level":"open_access","relation":"main_file","file_id":"21388","file_size":20688452,"checksum":"564041089e7334804ad3cade973f80b4"}],"oa":1,"date_created":"2026-03-02T10:08:38Z","abstract":[{"text":"Cell migration in vivo is often guided by chemical signaling, i.e., chemotaxis. For immune cells performing chemotaxis in the organism, this process is influenced by the complex geometry of the tissue environment. In this study, we use a theoretical model of branched cell migration on a network to explore the cellular response to chemical gradients. The model predicts the response of a branched cell to a chemical gradient: how the cell reorients its internal polarity and how it navigates through a complex environment up a chemical gradient. We then compare the model’s predictions with experimental observations of neutrophils migrating to the site of a laser-inflicted wound in a zebrafish larva fin, and neutrophils migrating in vitro inside a regular lattice of pillars. We find that the model captures the details of the subcellular response to the chemokine gradient, as well as qualitative characteristics of the large-scale migration, suggesting that the neutrophils behave as fast cells, which explains the functionality of these immune cells.","lang":"eng"}],"status":"public","quality_controlled":"1","OA_type":"gold","language":[{"iso":"eng"}],"OA_place":"publisher","has_accepted_license":"1","publication_identifier":{"eissn":["1553-7358"]},"citation":{"chicago":"Liu, Jiayi, Jonathan E. Ron, Giulia Rinaldi, Ivanna Williantarra, Antonios Georgantzoglou, Ingrid de Vries, Michael K Sixt, Milka Sarris, and Nir S. Gov. “Modelling Chemotaxis of Branched Cells in Complex Environments Provides Insights into Immune Cell Navigation.” PLOS Computational Biology. Public Library of Science, 2026. https://doi.org/10.1371/journal.pcbi.1013934.","ieee":"J. Liu et al., “Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation,” PLOS Computational Biology, vol. 22, no. 2. Public Library of Science, 2026.","ama":"Liu J, Ron JE, Rinaldi G, et al. Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation. PLOS Computational Biology. 2026;22(2). doi:10.1371/journal.pcbi.1013934","mla":"Liu, Jiayi, et al. “Modelling Chemotaxis of Branched Cells in Complex Environments Provides Insights into Immune Cell Navigation.” PLOS Computational Biology, vol. 22, no. 2, e1013934, Public Library of Science, 2026, doi:10.1371/journal.pcbi.1013934.","ista":"Liu J, Ron JE, Rinaldi G, Williantarra I, Georgantzoglou A, de Vries I, Sixt MK, Sarris M, Gov NS. 2026. Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation. PLOS Computational Biology. 22(2), e1013934.","short":"J. Liu, J.E. Ron, G. Rinaldi, I. Williantarra, A. Georgantzoglou, I. de Vries, M.K. Sixt, M. Sarris, N.S. Gov, PLOS Computational Biology 22 (2026).","apa":"Liu, J., Ron, J. E., Rinaldi, G., Williantarra, I., Georgantzoglou, A., de Vries, I., … Gov, N. S. (2026). Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation. PLOS Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1013934"},"department":[{"_id":"MiSi"}],"pmid":1,"external_id":{"pmid":["41632822"]},"_id":"21384","date_updated":"2026-03-02T14:12:22Z","article_processing_charge":"Yes","issue":"2","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"N.S.G. is the incumbent of the Lee and William Abramowitz Professorial Chair of Biophysics (Weizmann Institute), and acknowledges support from the Royal Society Wolfson Visiting Fellowship, and Human Frontier Science Program grant RGP0032/2022. Work by M.S., I.W., G.R. and A.G. was supported by the Leverhulme Trust (grant RPG-2021-226) and the European Research Council (ERC) under the Horizon 2020 program and UKRI, Grant agreement No.\r\nEP/Y02799X/1. M.S. and I.d.V acknowledge support by the European Research Council (grant ERC-SyG 101071793 to M.S). The funders had no role in study design, data collection and\r\nanalysis, decision to publish, or preparation of the manuscript.","file_date_updated":"2026-03-02T14:11:14Z","intvolume":" 22","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"PLOS Computational Biology","date_published":"2026-02-03T00:00:00Z","volume":22,"oa_version":"Published Version","publication_status":"published","publisher":"Public Library of Science"},{"title":"Average sizes of mixed character sums","month":"01","ddc":["510"],"PlanS_conform":"1","article_type":"original","page":"1-15","project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020"}],"author":[{"orcid":"0000-0002-0704-7026","last_name":"Wang","first_name":"Victor","id":"76096395-aea4-11ed-a680-ab8ebbd3f1b9","full_name":"Wang, Victor"},{"first_name":"Max","last_name":"Xu","full_name":"Xu, Max"}],"year":"2026","doi":"10.1017/prm.2026.10123","status":"public","quality_controlled":"1","arxiv":1,"corr_author":"1","type":"journal_article","oa":1,"date_created":"2026-03-02T10:09:23Z","abstract":[{"text":"We prove that the average size of a mixed character sum (math. formular) (for a suitable smooth function w) is on the order of √x for all irrational real θ satisfying a weak Diophantine condition, where χ is drawn from the family of Dirichlet characters modulo a large prime r and where x 6 r. In contrast, it was proved by Harper that the average size is o(√x) for rational θ. Certain quadratic Diophantine equations play a key role in the present paper. ","lang":"eng"}],"main_file_link":[{"url":"https://doi.org/10.1017/prm.2026.10123","open_access":"1"}],"_id":"21385","date_updated":"2026-03-02T14:05:47Z","article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","language":[{"iso":"eng"}],"OA_place":"publisher","has_accepted_license":"1","publication_identifier":{"eissn":["1473-7124"],"issn":["0308-2105"]},"citation":{"ama":"Wang V, Xu M. Average sizes of mixed character sums. Proceedings of the Royal Society of Edinburgh: Section A Mathematics. 2026:1-15. doi:10.1017/prm.2026.10123","mla":"Wang, Victor, and Max Xu. “Average Sizes of Mixed Character Sums.” Proceedings of the Royal Society of Edinburgh: Section A Mathematics, Cambridge University Press, 2026, pp. 1–15, doi:10.1017/prm.2026.10123.","short":"V. Wang, M. Xu, Proceedings of the Royal Society of Edinburgh: Section A Mathematics (2026) 1–15.","ista":"Wang V, Xu M. 2026. Average sizes of mixed character sums. Proceedings of the Royal Society of Edinburgh: Section A Mathematics., 1–15.","apa":"Wang, V., & Xu, M. (2026). Average sizes of mixed character sums. Proceedings of the Royal Society of Edinburgh: Section A Mathematics. Cambridge University Press. https://doi.org/10.1017/prm.2026.10123","chicago":"Wang, Victor, and Max Xu. “Average Sizes of Mixed Character Sums.” Proceedings of the Royal Society of Edinburgh: Section A Mathematics. Cambridge University Press, 2026. https://doi.org/10.1017/prm.2026.10123.","ieee":"V. Wang and M. Xu, “Average sizes of mixed character sums,” Proceedings of the Royal Society of Edinburgh: Section A Mathematics. Cambridge University Press, pp. 1–15, 2026."},"department":[{"_id":"TiBr"}],"external_id":{"arxiv":["2411.14181"]},"date_published":"2026-01-01T00:00:00Z","ec_funded":1,"oa_version":"Published Version","publication_status":"epub_ahead","publisher":"Cambridge University Press","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"We thank Ofir Gorodetsky, Andrew Granville, Adam Harper, Youness Lamzouri,\r\nKannan Soundararajan, Ping Xi, and Matt Young for their interest, helpful discussions, and comments. Special thanks are due to Jonathan Bober, Oleksiy Klurman,\r\nand Besfort Shala for sending us a letter about Question 1.3, and to Hung Bui\r\nfor informing us of [7]. V.W. thanks Stanford University for its hospitality and is supported by the European Union’s Horizon 2020 research and innovation program\r\nunder the Marie Skłodowska–Curie Grant Agreement No. 101034413. M.X. is supported by a Simons Junior Fellowship from the Simons Society of Fellows at the\r\nSimons Foundation.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Proceedings of the Royal Society of Edinburgh: Section A Mathematics"},{"publication_status":"submitted","corr_author":"1","status":"public","date_published":"2026-01-03T00:00:00Z","arxiv":1,"oa_version":"Preprint","date_created":"2026-03-04T12:09:26Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","abstract":[{"lang":"eng","text":"This document is a blueprint for the formalization in Lean of the structural theory of regular matroids underlying Seymour's decomposition theorem. We present a modular account of regularity via totally unimodular representations, show that regularity is preserved under 1-, 2-, and 3-sums, and establish regularity for several special classes of matroids, including graphic, cographic, and the matroid R10. The blueprint records the logical structure of the proof, the precise dependencies between results, and their correspondence with Lean declarations. It is intended both as a guide for the ongoing formalization effort and as a human-readable reference for the organization of the proof."}],"publication":"arXiv","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2601.01255"}],"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"type":"preprint","oa":1,"related_material":{"link":[{"url":"https://ivan-sergeyev.github.io/seymour/blueprint.pdf","relation":"supplementary_material"}]},"_id":"21400","title":"A blueprint for the formalization of Seymour's matroid decomposition theorem","date_updated":"2026-03-09T15:14:18Z","article_processing_charge":"No","month":"01","day":"03","citation":{"apa":"Sergeev, I., Dvorak, M., Rampell, C., Sandey, M., & Monticone, P. (n.d.). A blueprint for the formalization of Seymour’s matroid decomposition theorem. arXiv. https://doi.org/10.48550/arXiv.2601.01255","short":"I. Sergeev, M. Dvorak, C. Rampell, M. Sandey, P. Monticone, ArXiv (n.d.).","ista":"Sergeev I, Dvorak M, Rampell C, Sandey M, Monticone P. A blueprint for the formalization of Seymour’s matroid decomposition theorem. arXiv, 10.48550/arXiv.2601.01255.","ama":"Sergeev I, Dvorak M, Rampell C, Sandey M, Monticone P. A blueprint for the formalization of Seymour’s matroid decomposition theorem. arXiv. doi:10.48550/arXiv.2601.01255","mla":"Sergeev, Ivan, et al. “A Blueprint for the Formalization of Seymour’s Matroid Decomposition Theorem.” ArXiv, doi:10.48550/arXiv.2601.01255.","ieee":"I. Sergeev, M. Dvorak, C. Rampell, M. Sandey, and P. Monticone, “A blueprint for the formalization of Seymour’s matroid decomposition theorem,” arXiv. .","chicago":"Sergeev, Ivan, Martin Dvorak, Cameron Rampell, Mark Sandey, and Pietro Monticone. “A Blueprint for the Formalization of Seymour’s Matroid Decomposition Theorem.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2601.01255."},"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"page":"18","external_id":{"arxiv":["2601.01255"]},"author":[{"first_name":"Ivan","last_name":"Sergeev","orcid":"0009-0004-9145-8785","id":"ca3c9187-9a72-11ee-a009-8af825d896b0","full_name":"Sergeev, Ivan"},{"first_name":"Martin","last_name":"Dvorak","orcid":"0000-0001-5293-214X","full_name":"Dvorak, Martin","id":"40ED02A8-C8B4-11E9-A9C0-453BE6697425"},{"first_name":"Cameron","last_name":"Rampell","full_name":"Rampell, Cameron"},{"last_name":"Sandey","first_name":"Mark","full_name":"Sandey, Mark"},{"last_name":"Monticone","first_name":"Pietro","full_name":"Monticone, Pietro"}],"year":"2026","doi":"10.48550/arXiv.2601.01255","language":[{"iso":"eng"}],"OA_place":"repository"},{"external_id":{"pmid":["41774948"]},"citation":{"apa":"Jöst, A. B., Rodriguez Moreno, M. J., Kim, T., Baker, D. M., Yasuhara, M., Not, C. A., & Karanovic, I. (2026). Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. Elsevier. https://doi.org/10.1016/j.marpolbul.2026.119493","short":"A.B. Jöst, M.J. Rodriguez Moreno, T. Kim, D.M. Baker, M. Yasuhara, C.A. Not, I. Karanovic, Marine Pollution Bulletin 227 (2026).","ista":"Jöst AB, Rodriguez Moreno MJ, Kim T, Baker DM, Yasuhara M, Not CA, Karanovic I. 2026. Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. 227(6), 119493.","mla":"Jöst, Anna B., et al. “Ostracod Shell Chemistry as Proxy for Coastal Marine Conditions of a Highly Urbanized Megacity (Hong Kong SAR) and an Agro-Centric Oceanic Province (Jeju Island, Republic of Korea) – a Preliminary Comparative Analysis.” Marine Pollution Bulletin, vol. 227, no. 6, 119493, Elsevier, 2026, doi:10.1016/j.marpolbul.2026.119493.","ama":"Jöst AB, Rodriguez Moreno MJ, Kim T, et al. Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis. Marine Pollution Bulletin. 2026;227(6). doi:10.1016/j.marpolbul.2026.119493","ieee":"A. B. Jöst et al., “Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis,” Marine Pollution Bulletin, vol. 227, no. 6. Elsevier, 2026.","chicago":"Jöst, Anna B., Maximiliano J Rodriguez Moreno, Taihun Kim, David M. Baker, Moriaki Yasuhara, Christelle A. Not, and Ivana Karanovic. “Ostracod Shell Chemistry as Proxy for Coastal Marine Conditions of a Highly Urbanized Megacity (Hong Kong SAR) and an Agro-Centric Oceanic Province (Jeju Island, Republic of Korea) – a Preliminary Comparative Analysis.” Marine Pollution Bulletin. Elsevier, 2026. https://doi.org/10.1016/j.marpolbul.2026.119493."},"publication_identifier":{"eissn":["1879-3363"],"issn":["002-5326X"]},"pmid":1,"department":[{"_id":"FrPe"}],"OA_type":"closed access","language":[{"iso":"eng"}],"issue":"6","date_updated":"2026-03-09T10:19:45Z","article_processing_charge":"No","_id":"21406","publication":"Marine Pollution Bulletin","intvolume":" 227","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank the KIOST staff of the Jeju Marine Research Center for assisting sample collection, the research assistants and students of the Yoon Idea Lab led by Prof. Dr. Tae-Hyun Yoon at Hanyang University for facilitating and assisting in ICP-MS test runs involved in a pilot study preceding this study, Ms. Garance Perrois and Mr. Léonard Pons for assistance with statistics-related questions, and the two anonymous reviewers for their valuable comments and suggestions. The study described in this article was partially supported by grants from the Brain Pool Program through NRF funded by the Ministry of Science and ICT (reference code: 2019H1D3A1A01070922 to ABJ), by the Ministry of Oceans and Fisheries (grant number RS-2024-00406249 to TK), by the Korea Institute of Marine Science and Technology (KIMST), funded by the Ministry of Oceans and Fisheries (grant number RS-2025-02304432 to TK), and by the Korea Institute of Ocean Science and Technology (PEA0404 to TK).","publication_status":"published","publisher":"Elsevier","oa_version":"None","volume":227,"date_published":"2026-03-02T00:00:00Z","author":[{"first_name":"Anna B.","last_name":"Jöst","full_name":"Jöst, Anna B."},{"last_name":"Rodriguez Moreno","first_name":"Maximiliano J","id":"59bea3b2-8c82-11ef-a41a-af7b0efd9065","full_name":"Rodriguez Moreno, Maximiliano J"},{"full_name":"Kim, Taihun","first_name":"Taihun","last_name":"Kim"},{"first_name":"David M.","last_name":"Baker","full_name":"Baker, David M."},{"last_name":"Yasuhara","first_name":"Moriaki","full_name":"Yasuhara, Moriaki"},{"first_name":"Christelle A.","last_name":"Not","full_name":"Not, Christelle A."},{"full_name":"Karanovic, Ivana","last_name":"Karanovic","first_name":"Ivana"}],"year":"2026","doi":"10.1016/j.marpolbul.2026.119493","day":"02","scopus_import":"1","article_number":"119493","article_type":"original","month":"03","title":"Ostracod shell chemistry as proxy for coastal marine conditions of a highly urbanized megacity (Hong Kong SAR) and an agro-centric oceanic province (Jeju Island, Republic of Korea) – a preliminary comparative analysis","abstract":[{"text":"This preliminary study investigates the trace-element composition of ostracod shells (Ostracoda: Crustacea) as biogenic calcium carbonates in their role as environmental sentinels of pollution. Using high-resolution in-situ analysis, we compared two contrasting coastal systems: the highly urbanized seascape of metropolitan megacity Hong Kong (HKSAR) and the agriculturally dominated waters of rural retreat Jeju Island, Republic of Korea (ROK). The goal was to assess whether anthropogenic stress gradients affect trace element-to‑calcium ratios (E/Ca) in the carapaces of shallow-marine Neonesidea Maddocks, 1969 species. Hereby, the focus is laid on potential differences in the effects of extreme urbanization and extreme agriculturalization. We analyzed 12 trace elements commonly incorporated into ostracod shells using Inductively Coupled Plasma–Mass Spectrometry (ICP-MS). Only Mn/Ca, Mg/Ca, and Ni/Ca ratios showed strong correlations with specific seawater physicochemical parameters. Notably, Mn/Ca differed significantly between the two sites, seemingly driven mainly by variations in nitrite nitrogen levels. This suggests that Mn incorporation is sensitive to pollution source, urban versus agricultural, though species-specific uptake effects cannot be excluded. No significant differences in elemental uptake were found between adult and A-1 juvenile stages of Neonesidea mutsuensis Ishizaki, 1961 or Neonesidea elegans (Brady, 1969), supporting the use of both age groups in environmental reconstructions and increasing potential sample yields. While remaining empirical and exploratory, our tentative findings suggest that ostracod geochemistry holds promise for marine pollution monitoring and cautiously supports the application of ostracod Mn/Ca ratios to reconstruct anthropogenic, particularly nitrogen-related, impacts in nearshore environments using sediment core records.","lang":"eng"}],"date_created":"2026-03-08T23:01:44Z","type":"journal_article","quality_controlled":"1","status":"public"},{"publication":"Journal of Applied and Computational Topology","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":" 10","file_date_updated":"2026-03-09T11:29:30Z","acknowledgement":"The authors would like to thank Michael Lesnick and Primoz Skraba for their helpful comments regarding sparse approximations of filtrations. We are also grateful to the anonymous referees for their careful reading and constructive suggestions. The three authors are supported by the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), grant no. I 02979-N35, the U.S. National Science Foundation (NSF-DMS), grant no. 2005630, and a JSPS Grant-in-Aid for Transformative Research Areas (A) (22H05107, Y.H.), EPSRC Research Grant EP/Y008642/1.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","publication_status":"published","oa_version":"Published Version","date_published":"2026-03-01T00:00:00Z","volume":10,"external_id":{"arxiv":["2409.05241"]},"department":[{"_id":"HeEd"}],"publication_identifier":{"eissn":["2367-1734"],"issn":["2367-1726"]},"citation":{"short":"H. Edelsbrunner, M. Kahle, S. Kanazawa, Journal of Applied and Computational Topology 10 (2026).","ista":"Edelsbrunner H, Kahle M, Kanazawa S. 2026. Maximum persistent Betti numbers of Čech complexes. Journal of Applied and Computational Topology. 10, 5.","mla":"Edelsbrunner, Herbert, et al. “Maximum Persistent Betti Numbers of Čech Complexes.” Journal of Applied and Computational Topology, vol. 10, 5, Springer Nature, 2026, doi:10.1007/s41468-026-00233-3.","ama":"Edelsbrunner H, Kahle M, Kanazawa S. Maximum persistent Betti numbers of Čech complexes. Journal of Applied and Computational Topology. 2026;10. doi:10.1007/s41468-026-00233-3","apa":"Edelsbrunner, H., Kahle, M., & Kanazawa, S. (2026). Maximum persistent Betti numbers of Čech complexes. Journal of Applied and Computational Topology. Springer Nature. https://doi.org/10.1007/s41468-026-00233-3","ieee":"H. Edelsbrunner, M. Kahle, and S. Kanazawa, “Maximum persistent Betti numbers of Čech complexes,” Journal of Applied and Computational Topology, vol. 10. Springer Nature, 2026.","chicago":"Edelsbrunner, Herbert, Matthew Kahle, and Shu Kanazawa. “Maximum Persistent Betti Numbers of Čech Complexes.” Journal of Applied and Computational Topology. Springer Nature, 2026. https://doi.org/10.1007/s41468-026-00233-3."},"has_accepted_license":"1","OA_type":"hybrid","OA_place":"publisher","language":[{"iso":"eng"}],"article_processing_charge":"Yes (in subscription journal)","date_updated":"2026-03-09T11:31:29Z","_id":"21407","abstract":[{"lang":"eng","text":"This note proves that only a linear number of holes in a Cech complex of n points in R^d\r\ncan persist over an interval of constant length. Specifically, for any fixed dimension p <\r\nd and fixed ε > 0, the number of p-dimensional holes in the ˇ Cech complex at radius 1\r\nthat persist to radius 1+ε is bounded above by a constant times n,where n is the number\r\nof points. The proof uses a packing argument supported by relating theCˇ ech complexes\r\nwith corresponding snap complexes over the cells in a partition of space. The argument\r\nis self-contained and elementary, relying on geometric and combinatorial constructions\r\nrather than on the existing theory of sparse approximations or interleavings. The bound\r\nalso applies to Alpha complexes and Vietoris–Rips complexes. While our result can be\r\ninferred from prior work on sparse filtrations, to our knowledge, no explicit statement\r\nor direct proof of this bound appears in the literature."}],"date_created":"2026-03-08T23:01:45Z","file":[{"file_id":"21416","checksum":"0bf6dc430cafa40c08f260fe17d54595","file_size":323111,"creator":"dernst","access_level":"open_access","date_updated":"2026-03-09T11:29:30Z","relation":"main_file","success":1,"file_name":"2026_JourAppliedCompTopology_Edelsbrunner.pdf","content_type":"application/pdf","date_created":"2026-03-09T11:29:30Z"}],"oa":1,"type":"journal_article","arxiv":1,"quality_controlled":"1","status":"public","doi":"10.1007/s41468-026-00233-3","year":"2026","project":[{"name":"Mathematics, Computer Science","grant_number":"Z00342","call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425"},{"grant_number":"I02979-N35","call_identifier":"FWF","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","name":"Persistence and stability of geometric complexes"}],"author":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","first_name":"Herbert","orcid":"0000-0002-9823-6833"},{"full_name":"Kahle, Matthew","first_name":"Matthew","last_name":"Kahle"},{"first_name":"Shu","last_name":"Kanazawa","full_name":"Kanazawa, Shu"}],"scopus_import":"1","day":"01","article_number":"5","article_type":"original","PlanS_conform":"1","ddc":["500"],"month":"03","title":"Maximum persistent Betti numbers of Čech complexes"},{"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"The research was supported by the Gesellschaft für Forschungsförderung Niederösterreich under Project No. FTI23-G-011.","intvolume":" 164","file_date_updated":"2026-03-09T10:38:55Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Journal of Chemical Physics","volume":164,"date_published":"2026-02-28T00:00:00Z","oa_version":"Published Version","publication_status":"published","publisher":"AIP Publishing","OA_place":"publisher","language":[{"iso":"eng"}],"OA_type":"hybrid","has_accepted_license":"1","publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"citation":{"apa":"Hübl, M., & Goodrich, C. P. (2026). Simultaneous optimization of assembly time and yield in programmable self-assembly. Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/5.0304731","short":"M. Hübl, C.P. Goodrich, Journal of Chemical Physics 164 (2026).","ista":"Hübl M, Goodrich CP. 2026. Simultaneous optimization of assembly time and yield in programmable self-assembly. Journal of Chemical Physics. 164(8), 084904.","mla":"Hübl, Maximilian, and Carl Peter Goodrich. “Simultaneous Optimization of Assembly Time and Yield in Programmable Self-Assembly.” Journal of Chemical Physics, vol. 164, no. 8, 084904, AIP Publishing, 2026, doi:10.1063/5.0304731.","ama":"Hübl M, Goodrich CP. Simultaneous optimization of assembly time and yield in programmable self-assembly. Journal of Chemical Physics. 2026;164(8). doi:10.1063/5.0304731","ieee":"M. Hübl and C. P. Goodrich, “Simultaneous optimization of assembly time and yield in programmable self-assembly,” Journal of Chemical Physics, vol. 164, no. 8. AIP Publishing, 2026.","chicago":"Hübl, Maximilian, and Carl Peter Goodrich. “Simultaneous Optimization of Assembly Time and Yield in Programmable Self-Assembly.” Journal of Chemical Physics. AIP Publishing, 2026. https://doi.org/10.1063/5.0304731."},"department":[{"_id":"CaGo"},{"_id":"GradSch"}],"external_id":{"arxiv":["2510.07876"]},"_id":"21408","date_updated":"2026-03-09T10:40:41Z","article_processing_charge":"Yes (via OA deal)","issue":"8","type":"journal_article","file":[{"content_type":"application/pdf","date_created":"2026-03-09T10:38:55Z","file_name":"2026_JourChemPhysics_Huebl.pdf","success":1,"relation":"main_file","date_updated":"2026-03-09T10:38:55Z","access_level":"open_access","creator":"dernst","file_size":6903766,"checksum":"9bdb8870930e83edb973408da3038559","file_id":"21415"}],"oa":1,"date_created":"2026-03-08T23:01:45Z","abstract":[{"lang":"eng","text":"Rational design strategies for self-assembly require a detailed understanding of both the equilibrium state and the assembly kinetics. While the former is starting to be well understood, the latter remains a major theoretical challenge, especially in programmable systems and the so-called semi-addressable regime, where binding is often nondeterministic and the formation of off-target structures negatively influences the assembly. Here, we show that it is possible to simultaneously sculpt the assembly outcome and the assembly kinetics through the underexplored design space of binding energies and particle concentrations. By formulating the assembly process as a complex reaction network, we calculate and optimize the tradeoff between assembly speed and quality and show that parameter optimization can speed up assembly by many orders of magnitude without lowering the yield of the target structure. Although the exact speedup varies from design to design, we find the largest speedups for nondeterministic systems where unoptimized assembly is the slowest, sometimes even making them assemble faster than optimized, fully addressable designs. Therefore, these results not only solve a key challenge in semi-addressable self-assembly but further emphasize the utility of semi-addressability, where designs have the potential to be faster as well as cheaper (fewer particle species) and better (higher yield). More broadly, our results highlight the importance of parameter optimization in programmable self-assembly and provide practical tools for simultaneous optimization of kinetics and yield in a wide range of systems."}],"status":"public","quality_controlled":"1","arxiv":1,"corr_author":"1","article_type":"original","article_number":"084904","day":"28","scopus_import":"1","author":[{"first_name":"Maximilian","last_name":"Hübl","id":"5eb8629e-15b2-11ec-abd3-e6f3e5e01f32","full_name":"Hübl, Maximilian"},{"id":"EB352CD2-F68A-11E9-89C5-A432E6697425","full_name":"Goodrich, Carl Peter","last_name":"Goodrich","first_name":"Carl Peter","orcid":"0000-0002-1307-5074"}],"project":[{"_id":"8dd93da8-16d5-11f0-9cad-d2c70200d9a5","grant_number":"FTI23-G-011","name":"Dynamically reconfigurable self-assembly with triangular DNA-origami bricks"}],"doi":"10.1063/5.0304731","year":"2026","title":"Simultaneous optimization of assembly time and yield in programmable self-assembly","month":"02","ddc":["540"]}]