[{"author":[{"first_name":"Shweta","full_name":"Agrawal, Shweta","last_name":"Agrawal"},{"first_name":"Anuja","full_name":"Modi, Anuja","last_name":"Modi"},{"id":"dc8f1524-403e-11ee-bf07-9649ad996e21","first_name":"Anshu","last_name":"Yadav","full_name":"Yadav, Anshu"},{"first_name":"Shota","last_name":"Yamada","full_name":"Yamada, Shota"}],"oa":1,"intvolume":"     16269","publisher":"Springer Nature","_id":"20845","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","date_updated":"2025-12-29T11:51:13Z","title":"Zeroizing attacks against evasive and circular evasive LWE","year":"2025","doi":"10.1007/978-3-032-12293-3_9","publication_status":"published","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/375"}],"OA_place":"repository","month":"12","article_processing_charge":"No","OA_type":"green","department":[{"_id":"KrPi"}],"conference":{"location":"Aarhus, Denmark","start_date":"2025-12-01","name":"TCC: Theory of Cryptography","end_date":"2025-12-05"},"date_created":"2025-12-21T23:01:33Z","date_published":"2025-12-05T00:00:00Z","type":"conference","fulldoi":"https://doi.org/10.1007/978-3-032-12293-3_9","page":"259-290","publication":"23rd International Conference on Theory of Cryptography","scopus_import":"1","day":"05","abstract":[{"text":"We develop new attacks against the Evasive LWE family of assumptions, in both the public and private-coin regime. To the best of our knowledge, ours are the first attacks against Evasive LWE in the public-coin regime, for any instantiation from the family. Our attacks are summarized below.\r\n\r\nPublic-Coin Attacks.\r\n1.The recent work by Hseih, Lin and Luo [17] constructed the first Attribute Based Encryption (ABE) for unbounded depth circuits by relying on the “circular” evasive LWE assumption. This assumption has been popularly considered as a safe, public-coin instance of Evasive LWE in contrast to its “private-coin” cousins (for instance, see [10, 11]).\r\nWe provide the first attack against this assumption, challenging the widely held belief that this is a public-coin assumption.\r\n2. We demonstrate a counter-example against vanilla public-coin evasive LWE by Wee [26] in an unnatural parameter regime. Our attack crucially relies on the error in the pre-condition being larger than the error in the post-condition, necessitating a refinement of the assumption.\r\n\r\nPrivate-Coin Attacks.\r\n1. The recent work by Agrawal, Kumari and Yamada [2] constructed the first functional encryption scheme for pseudorandom functionalities (PRFE) and extended this to obfuscation for pseudorandom functionalities (PRIO) [4] by relying on private-coin evasive LWE. We provide a new attack against the assumption stated in the first posting of their work (subsequently refined to avoid these attacks).\r\n2. The recent work by Branco et al. [8] (concurrently to [4]) provides a construction of obfuscation for pseudorandom functionalities by relying on private-coin evasive LWE. We provide a new attack against their stated assumption.\r\n3. Branco et al. [8] showed that there exist contrived, “self-referential” classes of pseudorandom functionalities for which pseudorandom obfuscation cannot exist. We extend their techniques to develop an analogous result for pseudorandom functional encryption.\r\n\r\nWhile Evasive LWE was developed to specifically avoid “zeroizing attacks”, our work shows that in certain settings, such attacks can still apply.","lang":"eng"}],"volume":16269,"alternative_title":["LNCS"],"publication_identifier":{"issn":["0302-9743"],"isbn":["9783032122926"],"eissn":["1611-3349"]},"citation":{"mla":"Agrawal, Shweta, et al. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16269, Springer Nature, 2025, pp. 259–90, doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>.","ista":"Agrawal S, Modi A, Yadav A, Yamada S. 2025. Zeroizing attacks against evasive and circular evasive LWE. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16269, 259–290.","ama":"Agrawal S, Modi A, Yadav A, Yamada S. Zeroizing attacks against evasive and circular evasive LWE. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16269. Springer Nature; 2025:259-290. doi:<a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">10.1007/978-3-032-12293-3_9</a>","ieee":"S. Agrawal, A. Modi, A. Yadav, and S. Yamada, “Zeroizing attacks against evasive and circular evasive LWE,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16269, pp. 259–290.","chicago":"Agrawal, Shweta, Anuja Modi, Anshu Yadav, and Shota Yamada. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” In <i>23rd International Conference on Theory of Cryptography</i>, 16269:259–90. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>.","short":"S. Agrawal, A. Modi, A. Yadav, S. Yamada, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 259–290.","apa":"Agrawal, S., Modi, A., Yadav, A., &#38; Yamada, S. (2025). Zeroizing attacks against evasive and circular evasive LWE. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16269, pp. 259–290). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12293-3_9\">https://doi.org/10.1007/978-3-032-12293-3_9</a>"},"oa_version":"Preprint","acknowledgement":"We thank Rachel Lin for expressing concern about the applicability of “HJL-style” attacks [15] on the construction in [2] during a talk by the first author about [2]. This was the starting point of the investigation that led us to develop the attack in [5, Sec 4.1]. The first author also thanks Hoeteck Wee for sharing his rationale for introducing evasive LWE.\r\nThe first author is supported by the CyStar center of excellence, the VHAR faculty chair, and the C3iHub fellowship. The third author thanks Cystar, IIT Madras, for supporting a visit to IIT Madras during which the collaboration was initiated. The 4th author is partly supported by JST CREST Grant Number JPMJCR22M1.","language":[{"iso":"eng"}]},{"project":[{"grant_number":"F8509","name":"Security and Privacy by Design for Complex Systems","_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1"}],"day":"05","scopus_import":"1","alternative_title":["LNCS"],"volume":16271,"abstract":[{"lang":"eng","text":"CVRFs are PRFs that unify the properties of verifiable and constrained PRFs. Since they were introduced concurrently by Fuchsbauer and Chandran-Raghuraman-Vinayagamurthy in 2014, it has been an open problem to construct CVRFs without using heavy machinery such as multilinear maps, obfuscation or functional encryption.\r\nWe solve this problem by constructing a prefix-constrained verifiable PRF that does not rely on the aforementioned assumptions. Essentially, our construction is a verifiable version of the Goldreich-Goldwasser-Micali PRF. To achieve verifiability we leverage degree-2 algebraic PRGs and bilinear groups. In short, proofs consist of intermediate values of the Goldreich-Goldwasser-Micali PRF raised to the exponents of group elements. These outputs can be verified using pairings since the underlying PRG is of degree 2.\r\nWe prove the selective security of our construction under the Decisional Square Diffie-Hellman (DSDH) assumption and a new assumption, which we dub recursive Decisional Diffie-Hellman (recursive DDH).\r\nWe prove the soundness of recursive DDH in the generic group model assuming the hardness of the Multivariate Quadratic (MQ) problem and a new variant thereof, which we call MQ+.\r\nLast, in terms of applications, we observe that our CVRF is also an exponent (C)VRF in the plain model. Exponent VRFs were recently introduced by Boneh et al. (Eurocrypt’25) with various applications to threshold cryptography in mind. In addition to that, we give further applications for prefix-CVRFs in the blockchain setting, namely, stake-pooling and compressible randomness beacons."}],"page":"478-511","publication":"23rd International Conference on Theory of Cryptography","oa_version":"Preprint","acknowledgement":"We thank Jonas Steinbach and Gertjan De Mulder for helpful discussions on BIP 32, Dennis Hofheinz and Julia Kastner for helpful discussions on early prototypes of our CVRF, and Klaus Kraßnitzer for running pairing benchmarks on his MacBook Pro.\r\nChristoph U. Günther: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1611-3349"],"issn":["0302-9743"],"isbn":["9783032122896"]},"citation":{"apa":"Brandt, N., Cueto Noval, M., Günther, C. U., Ünal, A., &#38; Wohnig, S. (2025). Constrained verifiable random functions without obfuscation and friends. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16271, pp. 478–511). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>","short":"N. Brandt, M. Cueto Noval, C.U. Günther, A. Ünal, S. Wohnig, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 478–511.","ieee":"N. Brandt, M. Cueto Noval, C. U. Günther, A. Ünal, and S. Wohnig, “Constrained verifiable random functions without obfuscation and friends,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16271, pp. 478–511.","chicago":"Brandt, Nicholas, Miguel Cueto Noval, Christoph Ullrich Günther, Akin Ünal, and Stella Wohnig. “Constrained Verifiable Random Functions without Obfuscation and Friends.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:478–511. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">https://doi.org/10.1007/978-3-032-12290-2_16</a>.","ama":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. Constrained verifiable random functions without obfuscation and friends. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:478-511. doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>","ista":"Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. 2025. Constrained verifiable random functions without obfuscation and friends. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 478–511.","mla":"Brandt, Nicholas, et al. “Constrained Verifiable Random Functions without Obfuscation and Friends.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 478–511, doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_16\">10.1007/978-3-032-12290-2_16</a>."},"_id":"20846","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","doi":"10.1007/978-3-032-12290-2_16","year":"2025","date_updated":"2025-12-29T11:11:29Z","title":"Constrained verifiable random functions without obfuscation and friends","oa":1,"author":[{"first_name":"Nicholas","full_name":"Brandt, Nicholas","last_name":"Brandt"},{"first_name":"Miguel","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc","orcid":"0000-0002-2505-4246","last_name":"Cueto Noval","full_name":"Cueto Noval, Miguel"},{"first_name":"Christoph Ullrich","id":"ec98511c-eb8e-11eb-b029-edd25d7271a1","last_name":"Günther","full_name":"Günther, Christoph Ullrich"},{"first_name":"Akin","id":"f6b56fb6-dc63-11ee-9dbf-f6780863a85a","orcid":"0000-0002-8929-0221","last_name":"Ünal","full_name":"Ünal, Akin"},{"first_name":"Stella","last_name":"Wohnig","full_name":"Wohnig, Stella"}],"corr_author":"1","publisher":"Springer Nature","intvolume":"     16271","date_published":"2025-12-05T00:00:00Z","type":"conference","fulldoi":"https://doi.org/10.1007/978-3-032-12290-2_16","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/1045"}],"publication_status":"published","OA_type":"green","department":[{"_id":"KrPi"}],"article_processing_charge":"No","OA_place":"repository","month":"12","conference":{"start_date":"2025-12-01","location":"Aarhus, Denmark","end_date":"2025-12-05","name":"TCC: Theory of Cryptography"},"date_created":"2025-12-21T23:01:34Z"},{"ddc":["530"],"publication":"Physical Review E","license":"https://creativecommons.org/licenses/by/4.0/","ec_funded":1,"abstract":[{"text":"We report on an experimental active matter system with motion restricted to four cardinal directions. Our particles are magnetite-doped colloidal spheres driven by the Quincke electrorotational instability. The absence of a magnetic field (|𝑩|=0) leads to circular trajectories interspersed with short spontaneous runs. Intermediate fields (|𝑩|≲20mT) linearize the motion along the axis perpendicular to 𝑩. At high magnetic fields, we observe the surprising emergence of a second, distinct linearization along the axis parallel to 𝑩. With numerical simulations, we show that this behavior can be explained by anisotropic magnetic susceptibility.","lang":"eng"}],"volume":112,"scopus_import":"1","article_type":"original","day":"01","project":[{"grant_number":"E 298","name":"MixQUIckR: Mixing with QUIncke Rollers","_id":"bd8eede5-d553-11ed-ba76-eaded0d13485"},{"_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","grant_number":"949120","name":"Tribocharge: a multi-scale approach to an enduring problem in physics","call_identifier":"H2020"}],"citation":{"chicago":"Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>.","ieee":"E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter,” <i>Physical Review E</i>, vol. 112, no. 6. American Physical Society, 2025.","apa":"Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., &#38; Waitukaitis, S. R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>","short":"E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical Review E 112 (2025).","ista":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 112(6), 065418.","mla":"Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>, vol. 112, no. 6, 065418, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>.","ama":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. 2025;112(6). doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>"},"publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"file":[{"content_type":"application/pdf","date_created":"2025-12-29T11:15:42Z","file_name":"2025_PhysReviewE_Fitzgerald.pdf","checksum":"d593e933f976c3f3cde37ad66539d57d","creator":"dernst","file_size":2131491,"file_id":"20862","relation":"main_file","date_updated":"2025-12-29T11:15:42Z","access_level":"open_access","success":1}],"file_date_updated":"2025-12-29T11:15:42Z","language":[{"iso":"eng"}],"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant\r\nAgreement No. 949120). This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge the crucial contributions of Alexandre Morin in getting the project off the ground, and Jack Merrin for creating the SU-8 deposition protocol used in the construction of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their work on single-particle characterization. ","issue":"6","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"American Physical Society","intvolume":"       112","author":[{"id":"2df8ab8f-080d-11ed-979a-bfe651ca3afa","first_name":"Eavan","full_name":"Fitzgerald, Eavan","last_name":"Fitzgerald"},{"orcid":"0000-0002-1843-3803","id":"5f654c5d-04a1-11eb-ab36-ba9ffec58bd8","first_name":"Cécile","full_name":"Clavaud, Cécile","last_name":"Clavaud"},{"first_name":"Debasish","last_name":"Das","full_name":"Das, Debasish"},{"full_name":"Lenton, Isaac C","last_name":"Lenton","orcid":"0000-0002-5010-6984","first_name":"Isaac C","id":"a550210f-223c-11ec-8182-e2d45e817efb"},{"orcid":"0000-0002-2299-3176","first_name":"Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","full_name":"Waitukaitis, Scott R","last_name":"Waitukaitis"}],"corr_author":"1","oa":1,"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"date_updated":"2025-12-29T11:19:34Z","year":"2025","title":"Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter","doi":"10.1103/1ss8-31rb","has_accepted_license":"1","quality_controlled":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20847","PlanS_conform":"1","date_created":"2025-12-21T23:01:34Z","external_id":{"arxiv":["2508.05643"]},"article_number":"065418","OA_place":"publisher","article_processing_charge":"Yes (via OA deal)","month":"12","OA_type":"hybrid","department":[{"_id":"ScWa"}],"publication_status":"published","fulldoi":"https://doi.org/10.1103/1ss8-31rb","type":"journal_article","date_published":"2025-12-01T00:00:00Z","arxiv":1},{"ddc":["570"],"publication":"Genetics","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","scopus_import":"1","article_type":"original","day":"01","abstract":[{"text":"Genetic variation that influences complex disease susceptibility is introduced into the population by mutation and removed by natural selection and genetic drift. This mutation–selection–drift balance (MSDB) shapes the prevalence of a disease and its genetic architecture. To date, however, MSDB has been modeled only for monogenic (Mendelian) diseases. Here, we develop an MSDB model for complex disease susceptibility: we assume that genotype relates to disease risk according to the canonical liability threshold model and that the selection on variants affecting risk stems from the fitness cost of the disease. We focus on diseases that are highly polygenic, entail a substantial fitness cost, and are neither extremely common in the population nor exceedingly rare. The comparison of model predictions with genome-wide association studies and other observations in humans indicates that common genetic variation affecting complex disease susceptibility is little affected by directional selection and instead shaped by pleiotropic stabilizing selection on other traits. In turn, directional selection may exert a more substantial effect on rare, large-effect variants. Our results also suggest that current estimates of disease heritability are likely biased. The model thus provides a better understanding of the evolutionary processes that shape the architecture and prevalence of complex diseases.","lang":"eng"}],"volume":231,"publication_identifier":{"issn":["0016-6731"],"eissn":["1943-2631"]},"citation":{"apa":"Berg, J. J., Li, X., Riall, K., Hayward, L., &#38; Sella, G. (2025). Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>","short":"J.J. Berg, X. Li, K. Riall, L. Hayward, G. Sella, Genetics 231 (2025).","chicago":"Berg, Jeremy J., Xinyi Li, Kellen Riall, Laura Hayward, and Guy Sella. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/genetics/iyaf220\">https://doi.org/10.1093/genetics/iyaf220</a>.","ieee":"J. J. Berg, X. Li, K. Riall, L. Hayward, and G. Sella, “Mutation–selection–drift balance models of complex diseases,” <i>Genetics</i>, vol. 231, no. 4. Oxford University Press, 2025.","ama":"Berg JJ, Li X, Riall K, Hayward L, Sella G. Mutation–selection–drift balance models of complex diseases. <i>Genetics</i>. 2025;231(4). doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>","ista":"Berg JJ, Li X, Riall K, Hayward L, Sella G. 2025. Mutation–selection–drift balance models of complex diseases. Genetics. 231(4), iyaf220.","mla":"Berg, Jeremy J., et al. “Mutation–Selection–Drift Balance Models of Complex Diseases.” <i>Genetics</i>, vol. 231, no. 4, iyaf220, Oxford University Press, 2025, doi:<a href=\"https://doi.org/10.1093/genetics/iyaf220\">10.1093/genetics/iyaf220</a>."},"file_date_updated":"2025-12-29T11:27:51Z","file":[{"creator":"dernst","file_size":1182339,"relation":"main_file","file_id":"20863","date_updated":"2025-12-29T11:27:51Z","access_level":"open_access","success":1,"content_type":"application/pdf","date_created":"2025-12-29T11:27:51Z","file_name":"2025_Genetics_Berg.pdf","checksum":"b02eb6b78028b8bef435edc8435a8468"}],"acknowledgement":"We thank Nick Barton, Magnus Nordborg, John Novembre, Molly Przeworski, and Himani Sachdeva for many helpful discussions and for comments on the manuscript, and we thank Joshua Schraiber and 2 anonymous reviewers for comments on the manuscript. We also thank members of the Sella, Przeworski and Andolfatto labs at Columbia University, and the Berg, Novembre and Steinrücken labs at the University of Chicago, for feedback on the work at various stages. This work was completed in part with resources provided by the University of Chicago's Research Computing Center. This work was supported by National Institutes of Health F32 grant GM126787 and R35 grant GM151257 to J.J.B. and National Institutes of Health R01 grant GM115889 to G.S.","issue":"4","language":[{"iso":"eng"}],"oa_version":"Published Version","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"author":[{"first_name":"Jeremy J.","last_name":"Berg","full_name":"Berg, Jeremy J."},{"full_name":"Li, Xinyi","last_name":"Li","first_name":"Xinyi"},{"first_name":"Kellen","full_name":"Riall, Kellen","last_name":"Riall"},{"full_name":"Hayward, Laura","last_name":"Hayward","first_name":"Laura","id":"fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b"},{"first_name":"Guy","full_name":"Sella, Guy","last_name":"Sella"}],"oa":1,"publisher":"Oxford University Press","intvolume":"       231","status":"public","quality_controlled":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-12-29T11:29:16Z","year":"2025","title":"Mutation–selection–drift balance models of complex diseases","doi":"10.1093/genetics/iyaf220","_id":"20848","external_id":{"pmid":["41073879"]},"article_number":"iyaf220","date_created":"2025-12-21T23:01:34Z","publication_status":"published","OA_place":"publisher","article_processing_charge":"Yes (in subscription journal)","month":"12","department":[{"_id":"NiBa"}],"OA_type":"hybrid","fulldoi":"https://doi.org/10.1093/genetics/iyaf220","pmid":1,"date_published":"2025-12-01T00:00:00Z","type":"journal_article"},{"publication":"Contemporary Physics","page":"116-151","volume":66,"abstract":[{"text":"Studies of the distant Universe are providing key insights into our understanding of the formation of galaxies. The advent of the James Webb Space Telescope (JWST) has significantly enhanced our observational capabilities, leading to an expanded redshift frontier, providing unprecedented detail in the characterisation of early galaxies and enabling the discovery of new populations of accreting black holes. This review aims to provide an introduction to the basic processes and components that shape the observed spectra of galaxies, with a focus on their relevance to techniques with which high-redshift galaxies are selected. The review further introduces specific topics that have attracted significant attention in recent literature, including the discovery of highly efficient galaxy formation in the early Universe, the relation between galaxies and the process of reionization, new insights into the formation of the first stars and the enrichment of interstellar gas with heavy elements, and breakthroughs in our understanding of the origins of supermassive black holes.","lang":"eng"}],"day":"04","article_type":"original","scopus_import":"1","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","name":"Young galaxies as tracers and agents of cosmic reionization","grant_number":"101076224"}],"citation":{"ama":"Matthee JJ. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. 2025;66(1-4):116-151. doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>","ista":"Matthee JJ. 2025. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. 66(1–4), 116–151.","mla":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>, vol. 66, no. 1–4, Taylor &#38; Francis, 2025, pp. 116–51, doi:<a href=\"https://doi.org/10.1080/00107514.2025.2586370\">10.1080/00107514.2025.2586370</a>.","apa":"Matthee, J. J. (2025). JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. <i>Contemporary Physics</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>","short":"J.J. Matthee, Contemporary Physics 66 (2025) 116–151.","ieee":"J. J. Matthee, “JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies,” <i>Contemporary Physics</i>, vol. 66, no. 1–4. Taylor &#38; Francis, pp. 116–151, 2025.","chicago":"Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” <i>Contemporary Physics</i>. Taylor &#38; Francis, 2025. <a href=\"https://doi.org/10.1080/00107514.2025.2586370\">https://doi.org/10.1080/00107514.2025.2586370</a>."},"publication_identifier":{"eissn":["1366-5812"],"issn":["0010-7514"]},"language":[{"iso":"eng"}],"issue":"1-4","acknowledgement":"I thank Claudia Di Cesare, Edoardo Iani, Gauri Kotiwale and Wendy Sun for proofreading, Daichi Kashino, Gauri Kotiwale, Sara Mascia, Benjamín Navarette and Joris Witstok for their assistance in preparing some of the Figures, and Richard Ellis and Stephen Blundell for constructive comments. Funded by the European Union (ERC, AGENTS, 101076224).","oa_version":"Preprint","publisher":"Taylor & Francis","intvolume":"        66","corr_author":"1","oa":1,"author":[{"full_name":"Matthee, Jorryt J","last_name":"Matthee","orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J"}],"doi":"10.1080/00107514.2025.2586370","year":"2025","date_updated":"2026-04-07T08:44:00Z","title":"JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","quality_controlled":"1","status":"public","_id":"20864","date_created":"2025-12-29T12:05:25Z","external_id":{"arxiv":["2511.04843"]},"OA_type":"green","department":[{"_id":"JoMa"}],"OA_place":"repository","month":"12","article_processing_charge":"No","publication_status":"published","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2511.04843","open_access":"1"}],"fulldoi":"https://doi.org/10.1080/00107514.2025.2586370","type":"journal_article","date_published":"2025-12-04T00:00:00Z","arxiv":1},{"_id":"20866","status":"public","quality_controlled":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Hypernode automata","year":"2025","date_updated":"2026-01-05T12:27:41Z","doi":"10.1007/s00236-025-00509-8","corr_author":"1","oa":1,"author":[{"first_name":"Ezio","full_name":"Bartocci, Ezio","last_name":"Bartocci"},{"id":"87e34708-d6c6-11ec-9f5b-9391e7be2463","first_name":"Marek","last_name":"Chalupa","full_name":"Chalupa, Marek"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","orcid":"0000-0002-2985-7724","last_name":"Henzinger","full_name":"Henzinger, Thomas A"},{"last_name":"Nickovic","full_name":"Nickovic, Dejan","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87","first_name":"Dejan"},{"last_name":"Oliveira da Costa","full_name":"Oliveira da Costa, Ana","first_name":"Ana","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","orcid":"0000-0002-8741-5799"}],"intvolume":"        62","publisher":"Springer Nature","arxiv":1,"related_material":{"record":[{"status":"public","id":"14405","relation":"earlier_version"}]},"type":"journal_article","date_published":"2025-12-09T00:00:00Z","fulldoi":"https://doi.org/10.1007/s00236-025-00509-8","publication_status":"published","month":"12","article_processing_charge":"Yes (via OA deal)","OA_place":"publisher","OA_type":"hybrid","department":[{"_id":"ToHe"}],"external_id":{"arxiv":["2305.02836"]},"article_number":"43","date_created":"2025-12-29T12:07:12Z","project":[{"grant_number":"101020093","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"},{"_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502","name":"Interface Theory for Security and Privacy"}],"scopus_import":"1","day":"09","article_type":"original","abstract":[{"lang":"eng","text":"In this work, we present hypernode automata as a specification formalism for hyperproperties of systems whose executions may be misaligned among themselves, such as concurrent systems. These automata consist of nodes labeled with hypernode logic formulas and transitions marked with synchronizing actions. Hypernode logic formulas establish relations between sequences of variable values among different system executions. This logic enables both synchronous and asynchronous analysis of traces. In its asynchronous view on execution traces, hypernode formulas establish relations on the order of value changes for each variable without correlating their timing. In both views, the analysis of different execution traces is synchronized through the transitions of hypernode automata. By combining logic’s declarative nature with automata’s procedural power, hypernode automata seamlessly integrate asynchronicity requirements at the node level with synchronicity between node transitions. We show that the model-checking problem for hypernode automata is decidable for specifications where each node specifies either a synchronous or an asynchronous requirement for the system’s executions, but not both."}],"volume":62,"ec_funded":1,"publication":"Acta Informatica","ddc":["000"],"oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"This work was supported in part by the Austrian Science Fund (FWF) SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute of Science and Technology (IST Austria).","issue":"4","language":[{"iso":"eng"}],"file_date_updated":"2026-01-05T12:26:43Z","file":[{"success":1,"access_level":"open_access","date_updated":"2026-01-05T12:26:43Z","file_id":"20944","relation":"main_file","file_size":7117003,"creator":"dernst","checksum":"06ed45a1218ad8464818803ae2968aaf","file_name":"2025_ActaInformatica_Bartocci.pdf","date_created":"2026-01-05T12:26:43Z","content_type":"application/pdf"}],"publication_identifier":{"issn":["0001-5903"],"eissn":["1432-0525"]},"citation":{"ista":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Hypernode automata. Acta Informatica. 62(4), 43.","mla":"Bartocci, Ezio, et al. “Hypernode Automata.” <i>Acta Informatica</i>, vol. 62, no. 4, 43, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>.","ama":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. <i>Acta Informatica</i>. 2025;62(4). doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>","ieee":"E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” <i>Acta Informatica</i>, vol. 62, no. 4. Springer Nature, 2025.","chicago":"Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” <i>Acta Informatica</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>.","apa":"Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A. (2025). Hypernode automata. <i>Acta Informatica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>","short":"E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Acta Informatica 62 (2025)."}},{"_id":"20867","PlanS_conform":"1","title":"Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces","year":"2025","date_updated":"2026-01-05T12:19:09Z","doi":"10.2140/agt.2025.25.5153","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","quality_controlled":"1","intvolume":"        25","publisher":"Mathematical Sciences Publishers","oa":1,"corr_author":"1","author":[{"first_name":"Nicolò","id":"c8b3499c-7a77-11eb-b046-aa368cbbf2ad","orcid":"0000-0001-8686-1888","last_name":"Zava","full_name":"Zava, Nicolò"}],"type":"journal_article","date_published":"2025-11-20T00:00:00Z","arxiv":1,"fulldoi":"https://doi.org/10.2140/agt.2025.25.5153","article_processing_charge":"No","OA_place":"publisher","month":"11","department":[{"_id":"HeEd"}],"OA_type":"diamond","publication_status":"published","date_created":"2025-12-29T12:09:09Z","external_id":{"arxiv":["2303.04730"]},"project":[{"call_identifier":"FWF","grant_number":"I04245","name":"Algebraic Footprints of Geometric Features in Homology","_id":"26AD5D90-B435-11E9-9278-68D0E5697425"}],"abstract":[{"text":"We discuss the embeddability of subspaces of the Gromov–Hausdorff space, which consists of isometry classes of compact metric spaces endowed with the Gromov–Hausdorff distance, into Hilbert spaces. These embeddings are particularly valuable for applications to topological data analysis. We prove that its subspace consisting of metric spaces with at most n points has asymptotic dimension n(n−1)∕2. Thus, there exists a coarse embedding of that space into a Hilbert space. On the contrary, if the number of points is not bounded, then the subspace cannot be coarsely embedded into any uniformly convex Banach space and so, in particular, into any Hilbert space. Furthermore, we prove that, even if we restrict to finite metric spaces whose diameter is bounded by some constant, the subspace still cannot be bi-Lipschitz embedded into any finite-dimensional Hilbert space. We obtain both nonembeddability results by finding obstructions to coarse and bi-Lipschitz embeddings in families of isometry classes of finite subsets of the real line endowed with the Euclidean–Hausdorff distance.","lang":"eng"}],"volume":25,"scopus_import":"1","day":"20","article_type":"original","publication":"Algebraic & Geometric Topology","ddc":["500"],"page":"5153-5174","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"acknowledgement":"The author was supported by the FWF Grant, Project number I4245-N35. The author would like to thank Thomas Weighill for the helpful discussions around Theorem 3.10, and Takamitsu Yamauchi for bringing to my attention the fundamental reference [35]. Furthermore, the author\r\nis thankful for the detailed and helpful comments of the reviewer of this manuscript.","issue":"8","file":[{"file_name":"2025_AlgebraicGeomTopology_Zava.pdf","checksum":"1e05b4f17a44500ae1ae1e21bc636f6a","date_created":"2026-01-05T12:16:38Z","content_type":"application/pdf","access_level":"open_access","success":1,"date_updated":"2026-01-05T12:16:38Z","file_size":574389,"relation":"main_file","file_id":"20943","creator":"dernst"}],"file_date_updated":"2026-01-05T12:16:38Z","citation":{"apa":"Zava, N. (2025). Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>","short":"N. Zava, Algebraic &#38; Geometric Topology 25 (2025) 5153–5174.","ieee":"N. Zava, “Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces,” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8. Mathematical Sciences Publishers, pp. 5153–5174, 2025.","chicago":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>. Mathematical Sciences Publishers, 2025. <a href=\"https://doi.org/10.2140/agt.2025.25.5153\">https://doi.org/10.2140/agt.2025.25.5153</a>.","ama":"Zava N. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. <i>Algebraic &#38; Geometric Topology</i>. 2025;25(8):5153-5174. doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>","ista":"Zava N. 2025. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic &#38; Geometric Topology. 25(8), 5153–5174.","mla":"Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” <i>Algebraic &#38; Geometric Topology</i>, vol. 25, no. 8, Mathematical Sciences Publishers, 2025, pp. 5153–74, doi:<a href=\"https://doi.org/10.2140/agt.2025.25.5153\">10.2140/agt.2025.25.5153</a>."},"publication_identifier":{"eissn":["1472-2739"],"issn":["1472-2747"]}},{"acknowledgement":"This research was supported by the National Natural Science Foundation of China (grants 42288101 and 42175066) and Shanghai International Science and Technology Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554), the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.","issue":"12","language":[{"iso":"eng"}],"oa_version":"None","publication_identifier":{"issn":["2731-6076"]},"citation":{"ama":"Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. 2025;3(12):1532-1544. doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>","mla":"Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>.","ista":"Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N, Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G, Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S, Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V, Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T, Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 3(12), 1532–1544.","short":"C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti, E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser, S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski, M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen, L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater, J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner, I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer, K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis, B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia, Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade, X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh, T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544.","apa":"Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen, R. (2025). Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>","chicago":"Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>.","ieee":"C. Liang <i>et al.</i>, “Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai,” <i>Nature Mental Health</i>, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025."},"scopus_import":"1","article_type":"original","day":"01","abstract":[{"text":"Residents of low-latitude megacities face growing vulnerability to humid-heat stress under urbanization and global warming, yet limited research has assessed the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat exposures in these cities. Here we quantify the hospital admissions of MBDs in Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat, and project future burdens under various greenhouse gas (GHG)-emission and population scenarios. Humid heat drives a higher morbidity burden than high temperature alone, especially in humid-heat nights. Without population change, the humid-heat-related morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval 56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465 (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing emissions to the lowest pathway. With projected population decline, the attributable hospital admissions will decrease toward century’s end. These findings highlight the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme humid heat.","lang":"eng"}],"volume":3,"project":[{"name":"Reducing the impact of major environmental challenges on mental health","grant_number":"101057429","_id":"349d1832-11ca-11ed-8bc3-d79b574010e0"}],"page":"1532-1544","publication":"Nature Mental Health","fulldoi":"https://doi.org/10.1038/s44220-025-00519-y","date_published":"2025-12-01T00:00:00Z","type":"journal_article","date_created":"2025-12-29T12:11:28Z","publication_status":"published","article_processing_charge":"No","month":"12","department":[{"_id":"GaNo"}],"OA_type":"closed access","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_updated":"2026-01-05T12:02:29Z","title":"Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai","year":"2025","doi":"10.1038/s44220-025-00519-y","_id":"20868","author":[{"first_name":"Chen","full_name":"Liang, Chen","last_name":"Liang"},{"first_name":"Jiacan","full_name":"Yuan, Jiacan","last_name":"Yuan"},{"first_name":"Renhe","last_name":"Zhang","full_name":"Zhang, Renhe"},{"first_name":"Xu","full_name":"Tang, Xu","last_name":"Tang"},{"first_name":"Gunter","full_name":"Schumann, Gunter","last_name":"Schumann"},{"first_name":"Esther","full_name":"Hitchen, Esther","last_name":"Hitchen"},{"first_name":"Elli","full_name":"Polemiti, Elli","last_name":"Polemiti"},{"last_name":"Serin","full_name":"Serin, Emin","first_name":"Emin"},{"first_name":"Hedi","last_name":"Kebir","full_name":"Kebir, Hedi"},{"last_name":"Lett","full_name":"Lett, Tristram A.","first_name":"Tristram A."},{"full_name":"Vaidya, Nilakshi","last_name":"Vaidya","first_name":"Nilakshi"},{"first_name":"Jean-Charles","last_name":"Roy","full_name":"Roy, Jean-Charles"},{"full_name":"Walter, Henrik","last_name":"Walter","first_name":"Henrik"},{"first_name":"Andreas","last_name":"Heinz","full_name":"Heinz, Andreas"},{"first_name":"Markus","full_name":"Ralser, Markus","last_name":"Ralser"},{"last_name":"Twardziok","full_name":"Twardziok, Sven","first_name":"Sven"},{"last_name":"Eils","full_name":"Eils, Roland","first_name":"Roland"},{"full_name":"Jentsch, Marcel","last_name":"Jentsch","first_name":"Marcel"},{"last_name":"Taron","full_name":"Taron, Ulrike-Helene","first_name":"Ulrike-Helene"},{"first_name":"Tatjana","full_name":"Schütz, Tatjana","last_name":"Schütz"},{"first_name":"Kerstin","full_name":"Schepanski, Kerstin","last_name":"Schepanski"},{"last_name":"Banaschewski","full_name":"Banaschewski, Tobias","first_name":"Tobias"},{"full_name":"Neidhart, Maja","last_name":"Neidhart","first_name":"Maja"},{"last_name":"Meyer-Lindenberg","full_name":"Meyer-Lindenberg, Andreas","first_name":"Andreas"},{"first_name":"Heike","full_name":"Tost, Heike","last_name":"Tost"},{"full_name":"Holz, Nathalie","last_name":"Holz","first_name":"Nathalie"},{"full_name":"Schwarz, Emanuel","last_name":"Schwarz","first_name":"Emanuel"},{"first_name":"Argyris","last_name":"Stringaris","full_name":"Stringaris, Argyris"},{"first_name":"Nina","full_name":"Christmann, Nina","last_name":"Christmann"},{"first_name":"Karina","last_name":"Janson","full_name":"Janson, Karina"},{"last_name":"Nees","full_name":"Nees, Frauke","first_name":"Frauke"},{"first_name":"Maja","last_name":"Neidhart","full_name":"Neidhart, Maja"},{"last_name":"Seefried","full_name":"Seefried, Beke","first_name":"Beke"},{"first_name":"Rieke","last_name":"Aden","full_name":"Aden, Rieke"},{"first_name":"Ole A.","last_name":"Andreassen","full_name":"Andreassen, Ole A."},{"full_name":"Westlye, Lars T.","last_name":"Westlye","first_name":"Lars T."},{"full_name":"van der Meer, Dennis","last_name":"van der Meer","first_name":"Dennis"},{"last_name":"Fernández-Cabello","full_name":"Fernández-Cabello, Sara","first_name":"Sara"},{"full_name":"Kjelkenes, Rikka","last_name":"Kjelkenes","first_name":"Rikka"},{"first_name":"Helga","last_name":"Ask","full_name":"Ask, Helga"},{"first_name":"Michael","last_name":"Rapp","full_name":"Rapp, Michael"},{"last_name":"Tschorn","full_name":"Tschorn, Mira","first_name":"Mira"},{"full_name":"Böttger, Sarah Jane","last_name":"Böttger","first_name":"Sarah Jane"},{"full_name":"Marquand, Andre","last_name":"Marquand","first_name":"Andre"},{"first_name":"Antoine","full_name":"Bernas, Antoine","last_name":"Bernas"},{"full_name":"Novarino, Gaia","last_name":"Novarino","orcid":"0000-0002-7673-7178","first_name":"Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Mel","full_name":"Slater, Mel","last_name":"Slater"},{"first_name":"Jaime","last_name":"Gallego","full_name":"Gallego, Jaime"},{"first_name":"Álvaro","last_name":"Pastor","full_name":"Pastor, Álvaro"},{"first_name":"Guillem","full_name":"Feixas, Guillem","last_name":"Feixas"},{"full_name":"Eiroa-Orosa, Francisco José","last_name":"Eiroa-Orosa","first_name":"Francisco José"},{"last_name":"Nöthen","full_name":"Nöthen, Markus M.","first_name":"Markus M."},{"first_name":"Andreas J.","last_name":"Forstner","full_name":"Forstner, Andreas J."},{"first_name":"Isabelle","full_name":"Claus, Isabelle","last_name":"Claus"},{"first_name":"Carina","full_name":"Mathey, Carina","last_name":"Mathey"},{"full_name":"Heilmann-Heimbach, Stefanie","last_name":"Heilmann-Heimbach","first_name":"Stefanie"},{"first_name":"Per","full_name":"Hoffmann, Per","last_name":"Hoffmann"},{"first_name":"Abigail","full_name":"Miller, Abigail","last_name":"Miller"},{"first_name":"Peter","last_name":"Sommer","full_name":"Sommer, Peter"},{"last_name":"Schmitt","full_name":"Schmitt, Karen","first_name":"Karen"},{"first_name":"Johannes","last_name":"Wilbertz","full_name":"Wilbertz, Johannes"},{"first_name":"Myrto","full_name":"Patraskaki, Myrto","last_name":"Patraskaki"},{"first_name":"Viktor","last_name":"Jirsa","full_name":"Jirsa, Viktor"},{"first_name":"Spase","full_name":"Petkoski, Spase","last_name":"Petkoski"},{"first_name":"Anastasios-Polykarpos","full_name":"Athanasiadis, Anastasios-Polykarpos","last_name":"Athanasiadis"},{"full_name":"Spanlang, Bernhard","last_name":"Spanlang","first_name":"Bernhard"},{"full_name":"Pearmund, Charlie","last_name":"Pearmund","first_name":"Charlie"},{"first_name":"Sören","last_name":"Hese","full_name":"Hese, Sören"},{"first_name":"Paul","last_name":"Renner","full_name":"Renner, Paul"},{"first_name":"Tianye","last_name":"Jia","full_name":"Jia, Tianye"},{"full_name":"Chang, Xiao","last_name":"Chang","first_name":"Xiao"},{"first_name":"Yuxiang","full_name":"Dai, Yuxiang","last_name":"Dai"},{"first_name":"Yunman","full_name":"Xia, Yunman","last_name":"Xia"},{"full_name":"Li, Yuzhu","last_name":"Li","first_name":"Yuzhu"},{"full_name":"Zhang, Yanqing","last_name":"Zhang","first_name":"Yanqing"},{"last_name":"Calhoun","full_name":"Calhoun, Vince","first_name":"Vince"},{"full_name":"Thompson, Paul","last_name":"Thompson","first_name":"Paul"},{"full_name":"Clinton, Nicholas","last_name":"Clinton","first_name":"Nicholas"},{"last_name":"Desrivières","full_name":"Desrivières, Sylvane","first_name":"Sylvane"},{"full_name":"Agunbiade, Kofoworola","last_name":"Agunbiade","first_name":"Kofoworola"},{"first_name":"Xinyang","last_name":"Yu","full_name":"Yu, Xinyang"},{"last_name":"Zhang","full_name":"Zhang, Zuo","first_name":"Zuo"},{"first_name":"Di","last_name":"Chen","full_name":"Chen, Di"},{"first_name":"Allan H.","full_name":"Young, Allan H.","last_name":"Young"},{"first_name":"Ameli","full_name":"Schwalber, Ameli","last_name":"Schwalber"},{"first_name":"Vanessa","last_name":"Köhler","full_name":"Köhler, Vanessa"},{"full_name":"Stahl, Bernd","last_name":"Stahl","first_name":"Bernd"},{"first_name":"George","full_name":"Ogoh, George","last_name":"Ogoh"},{"first_name":"Tamara","full_name":"Schikowski, Tamara","last_name":"Schikowski"},{"first_name":"Ragnhild","full_name":"Brandlistuen, Ragnhild","last_name":"Brandlistuen"}],"intvolume":"         3","publisher":"Springer Nature"},{"citation":{"ama":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. 2025;112(12). doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>","ista":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. American Journal of Botany. 112(12), e70129.","mla":"Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>, vol. 112, no. 12, e70129, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>.","apa":"Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., &#38; Baskett, C. (2025). Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. Wiley. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>","short":"A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of Botany 112 (2025).","ieee":"A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors,” <i>American Journal of Botany</i>, vol. 112, no. 12. Wiley, 2025.","chicago":"Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>."},"publication_identifier":{"issn":["0002-9122"],"eissn":["1537-2197"]},"oa_version":"None","language":[{"iso":"eng"}],"acknowledgement":"Thank you to Doug Schemske and Nick Barton forcritically reviewing the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for their thoughtfulcomments and suggestions, which substantially improved the clarity and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon 2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement No. 754411","issue":"12","ec_funded":1,"publication":"American Journal of Botany","project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"abstract":[{"lang":"eng","text":"Premise: What maintains trait divergence in the face of gene flow? Two varieties of wild snapdragon (Antirrhinum majus) characterized by divergent flower color hybridize in their native range. Selection on flower color genes is indicated by sharp clines, but the selective agents have not been demonstrated. Although previous work has focused on pollinators, pigmentation genes can also contribute to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates stress tolerance, which could contribute to hybrid zone maintenance through parental niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus, yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods: We experimentally compared drought tolerance of each morphotype from allopatric crosses within and between varieties using three greenhouse treatments. Control plants were watered as needed, while drought-treated plants were watered half as often, either from the transplant stage (“early” drought), or from flowering onset (“late” drought).\r\nResults: Parental morphotypes responded identically to drought in fitness and most phenotypic traits. However, hybrids had lower survival (14%) under late drought stress than parental morphotypes (70%). All hybrids that flowered in the late drought treatment died, compared to ~20% of flowering parental morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially contribute to flower color divergence in the face of gene flow in A. majus. Further research should test the relevance of our results to field conditions and explicitly probe the role of flower color genes in drought tolerance."}],"volume":112,"scopus_import":"1","day":"01","article_type":"original","month":"12","article_processing_charge":"No","OA_type":"closed access","department":[{"_id":"NiBa"}],"publication_status":"published","date_created":"2025-12-29T12:14:26Z","external_id":{"pmid":["41327576 "]},"article_number":"e70129","date_published":"2025-12-01T00:00:00Z","type":"journal_article","pmid":1,"related_material":{"link":[{"url":"https://github.com/Alex-Fuster/hybrids_drought","relation":"software"}]},"fulldoi":"https://doi.org/10.1002/ajb2.70129","intvolume":"       112","publisher":"Wiley","author":[{"last_name":"Fuster‐Calvo","full_name":"Fuster‐Calvo, Alexandre","first_name":"Alexandre"},{"first_name":"Coline C.","full_name":"Jaworski, Coline C.","last_name":"Jaworski"},{"orcid":"0000-0002-8511-0254","id":"3153D6D4-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas","full_name":"Ellis, Thomas","last_name":"Ellis"},{"orcid":"0000-0002-7354-8574","id":"3B4A7CE2-F248-11E8-B48F-1D18A9856A87","first_name":"Carina","full_name":"Baskett, Carina","last_name":"Baskett"}],"_id":"20869","date_updated":"2026-01-05T11:56:22Z","year":"2025","title":"Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors","doi":"10.1002/ajb2.70129","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public"},{"citation":{"apa":"Stopa, V., Sopić, M., Li, G., Sluimer, J., Basílio, J., van der Laan, S. W., … Hochreiter, B. (2025). Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In Y. Devaux &#38; M. Sopic (Eds.), <i>Transcriptomics in Atherosclerosis</i> (pp. 131–172). Elsevier. <a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">https://doi.org/10.1016/b978-0-443-33064-3.00016-5</a>","short":"V. Stopa, M. Sopić, G. Li, J. Sluimer, J. Basílio, S.W. van der Laan, D.P. Kreil, Y. Devaux, B. Hochreiter, in:, Y. Devaux, M. Sopic (Eds.), Transcriptomics in Atherosclerosis, Elsevier, 2025, pp. 131–172.","ieee":"V. Stopa <i>et al.</i>, “Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond,” in <i>Transcriptomics in Atherosclerosis</i>, Y. Devaux and M. Sopic, Eds. Elsevier, 2025, pp. 131–172.","chicago":"Stopa, Victoria, Miron Sopić, Guanliang Li, Judith Sluimer, José Basílio, Sander W. van der Laan, David P. Kreil, Yvan Devaux, and Bernhard Hochreiter. “Essentials of Transcriptomic Methods: Navigating through RNA Sequencing and Beyond.” In <i>Transcriptomics in Atherosclerosis</i>, edited by Yvan Devaux and Miron Sopic, 131–72. Elsevier, 2025. <a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">https://doi.org/10.1016/b978-0-443-33064-3.00016-5</a>.","ama":"Stopa V, Sopić M, Li G, et al. Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In: Devaux Y, Sopic M, eds. <i>Transcriptomics in Atherosclerosis</i>. Elsevier; 2025:131-172. doi:<a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">10.1016/b978-0-443-33064-3.00016-5</a>","ista":"Stopa V, Sopić M, Li G, Sluimer J, Basílio J, van der Laan SW, Kreil DP, Devaux Y, Hochreiter B. 2025.Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond. In: Transcriptomics in Atherosclerosis. , 131–172.","mla":"Stopa, Victoria, et al. “Essentials of Transcriptomic Methods: Navigating through RNA Sequencing and Beyond.” <i>Transcriptomics in Atherosclerosis</i>, edited by Yvan Devaux and Miron Sopic, Elsevier, 2025, pp. 131–72, doi:<a href=\"https://doi.org/10.1016/b978-0-443-33064-3.00016-5\">10.1016/b978-0-443-33064-3.00016-5</a>."},"date_created":"2025-12-29T12:16:22Z","publication_identifier":{"isbn":["9780443330643"]},"department":[{"_id":"Bio"}],"OA_type":"closed access","article_processing_charge":"No","month":"10","publication_status":"published","language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1016/b978-0-443-33064-3.00016-5","type":"book_chapter","date_published":"2025-10-24T00:00:00Z","oa_version":"None","publication":"Transcriptomics in Atherosclerosis","publisher":"Elsevier","page":"131-172","author":[{"full_name":"Stopa, Victoria","last_name":"Stopa","first_name":"Victoria"},{"last_name":"Sopić","full_name":"Sopić, Miron","first_name":"Miron"},{"first_name":"Guanliang","last_name":"Li","full_name":"Li, Guanliang"},{"first_name":"Judith","full_name":"Sluimer, Judith","last_name":"Sluimer"},{"first_name":"José","last_name":"Basílio","full_name":"Basílio, José"},{"first_name":"Sander W.","last_name":"van der Laan","full_name":"van der Laan, Sander W."},{"first_name":"David P.","last_name":"Kreil","full_name":"Kreil, David P."},{"last_name":"Devaux","full_name":"Devaux, Yvan","first_name":"Yvan"},{"full_name":"Hochreiter, Bernhard","last_name":"Hochreiter","first_name":"Bernhard","id":"e6cab3de-17f6-11ed-9210-c1e42e045e9d"}],"doi":"10.1016/b978-0-443-33064-3.00016-5","date_updated":"2026-01-05T11:49:54Z","abstract":[{"lang":"eng","text":"RNA sequencing (RNA-seq) methodologies have evolved rapidly, offering powerful tools to study gene expression, transcriptome dynamics, and molecular mechanisms in various biological contexts. However, the complexity of these approaches poses challenges in data interpretation, sensitivity, and applicability. This chapter provides a comprehensive overview of RNA-seq methodologies, highlighting their advantages, limitations, and applications, particularly in cardiovascular research. Bulk RNA sequencing enables high-throughput gene expression profiling but lacks the resolution to capture cellular heterogeneity and spatial context. Direct RNA sequencing preserves native RNA modifications, offering insights into post-transcriptional regulation, though it remains technically challenging. Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) bridge these gaps by resolving transcriptomic complexity at the cellular level and within tissue architecture, providing crucial insights into disease mechanisms such as atherosclerosis. By summarizing the strengths and limitations of these methodologies, this chapter aims to guide researchers in selecting the most suitable transcriptomic approach for their studies, ultimately advancing precision medicine and biomarker discovery in cardiovascular disease."}],"year":"2025","title":"Essentials of transcriptomic methods: Navigating through RNA sequencing and beyond","day":"24","quality_controlled":"1","scopus_import":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20870","editor":[{"first_name":"Yvan","last_name":"Devaux","full_name":"Devaux, Yvan"},{"first_name":"Miron","last_name":"Sopic","full_name":"Sopic, Miron"}]},{"oa_version":"None","language":[{"iso":"eng"}],"issue":"12","acknowledgement":"The authors are thankful for the financial support provided by the Ministry of Education, India, and MNNIT Allahabad, as well as for the necessary equipment, computing facilities, and overall support to carry out this study.","citation":{"ieee":"B. Khatoon, V. K. Chaudhary, S. Kamil, S. U. Hasan, and M. S. Alam, “Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation,” <i>Physics of Fluids</i>, vol. 37, no. 12. AIP Publishing, 2025.","chicago":"Khatoon, Bushra, Vikas K. Chaudhary, Shoaib Kamil, Shabih Ul Hasan, and M. Siraj Alam. “Enhanced Mass Transfer in Microgeometry Using Pulsating Velocity Inputs: Hydrodynamic Analysis and Numerical Simulation.” <i>Physics of Fluids</i>. AIP Publishing, 2025. <a href=\"https://doi.org/10.1063/5.0303132\">https://doi.org/10.1063/5.0303132</a>.","apa":"Khatoon, B., Chaudhary, V. K., Kamil, S., Hasan, S. U., &#38; Alam, M. S. (2025). Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. <i>Physics of Fluids</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0303132\">https://doi.org/10.1063/5.0303132</a>","short":"B. Khatoon, V.K. Chaudhary, S. Kamil, S.U. Hasan, M.S. Alam, Physics of Fluids 37 (2025).","ista":"Khatoon B, Chaudhary VK, Kamil S, Hasan SU, Alam MS. 2025. Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. Physics of Fluids. 37(12), 122012.","mla":"Khatoon, Bushra, et al. “Enhanced Mass Transfer in Microgeometry Using Pulsating Velocity Inputs: Hydrodynamic Analysis and Numerical Simulation.” <i>Physics of Fluids</i>, vol. 37, no. 12, 122012, AIP Publishing, 2025, doi:<a href=\"https://doi.org/10.1063/5.0303132\">10.1063/5.0303132</a>.","ama":"Khatoon B, Chaudhary VK, Kamil S, Hasan SU, Alam MS. Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation. <i>Physics of Fluids</i>. 2025;37(12). doi:<a href=\"https://doi.org/10.1063/5.0303132\">10.1063/5.0303132</a>"},"publication_identifier":{"eissn":["1089-7666"],"issn":["1070-6631"]},"volume":37,"abstract":[{"text":"The current work focuses on the performance of hydrodynamics and mass transfer in a microchannel. A hydrodynamic model is developed for a gas–liquid (CO2–water) system and slug flow pattern. For the first time in literature, a concept of pulsating velocity input is introduced in an enhanced cross-T-junction microchannel to study the mass transfer using the physical absorption mechanism in ANSYS FLUENT R2 2024. The mass transfer model is associated with the hydrodynamic model and some user-defined functions in FLUENT. This work demonstrates that incorporating obstructions and applying trapezoidal and sinusoidal wave inputs improve the CO2 absorption rate. The obtained data are further compared with the plain T-junction microchannel in terms of mass transfer coefficient. Solubility of CO2 in three different solvents (ethyl alcohol, water, and ethylene glycol) has been revealed in an enhanced cross T-junction microchannel at two different temperatures, i.e., 298.15 and 303.15 K. The numerical simulations illustrate that an increase in temperature has an adverse effect on the mass transfer rate.","lang":"eng"}],"article_type":"original","day":"01","scopus_import":"1","publication":"Physics of Fluids","date_published":"2025-12-01T00:00:00Z","type":"journal_article","fulldoi":"https://doi.org/10.1063/5.0303132","department":[{"_id":"BjHo"}],"OA_type":"closed access","article_processing_charge":"No","month":"12","publication_status":"published","date_created":"2026-01-04T23:01:34Z","article_number":"122012","_id":"20928","doi":"10.1063/5.0303132","date_updated":"2026-01-05T10:54:15Z","title":"Enhanced mass transfer in microgeometry using pulsating velocity inputs: Hydrodynamic analysis and numerical simulation","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","intvolume":"        37","publisher":"AIP Publishing","author":[{"full_name":"Khatoon, Bushra","last_name":"Khatoon","first_name":"Bushra"},{"first_name":"Vikas K.","full_name":"Chaudhary, Vikas K.","last_name":"Chaudhary"},{"id":"185a19af-dc7d-11ea-9b2f-8eb2201959e9","first_name":"Shoaib","full_name":"Kamil, Shoaib","last_name":"Kamil"},{"first_name":"Shabih Ul","last_name":"Hasan","full_name":"Hasan, Shabih Ul"},{"full_name":"Alam, M. Siraj","last_name":"Alam","first_name":"M. Siraj"}]},{"intvolume":"        16","publisher":"Springer Nature","oa":1,"corr_author":"1","APC_amount":"7068 EUR","author":[{"orcid":"0000-0001-8945-6992","id":"C407B586-6052-11E9-B3AE-7006E6697425","first_name":"Murat","full_name":"Artan, Murat","last_name":"Artan"},{"last_name":"Schön","full_name":"Schön, Hanna","first_name":"Hanna","id":"C8E17EDC-D7AA-11E9-B7B7-45ECE5697425"},{"orcid":"0000-0001-8347-0443","first_name":"Mario","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","full_name":"De Bono, Mario","last_name":"De Bono"}],"doi":"10.1038/s41467-025-66409-0","year":"2025","acknowledged_ssus":[{"_id":"Bio"}],"title":"Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins","date_updated":"2026-05-20T08:10:18Z","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","quality_controlled":"1","_id":"20929","PlanS_conform":"1","date_created":"2026-01-04T23:01:34Z","article_number":"11355","external_id":{"pmid":["41381452"]},"department":[{"_id":"MaDe"}],"OA_type":"gold","month":"12","article_processing_charge":"Yes","OA_place":"publisher","publication_status":"published","fulldoi":"https://doi.org/10.1038/s41467-025-66409-0","type":"journal_article","date_published":"2025-12-11T00:00:00Z","DOAJ_listed":"1","pmid":1,"ddc":["570"],"publication":"Nature Communications","ec_funded":1,"volume":16,"abstract":[{"lang":"eng","text":"Insulin/insulin-like growth factor signaling inhibits FOXO transcription factors to control development, homeostasis, and aging. Here, we use proximity labeling to identify proteins interacting with the C. elegans FOXO DAF-16. We show that in well-fed, unstressed animals harboring active insulin signaling, DAF-16 forms a complex with the PAR-1/MARK serine/threonine kinase, a key regulator of cell polarity. PAR-1 inhibits DAF-16 accumulation and promotes DAF-16 phosphorylation at S249, at a conserved motif that PAR-1/human MARK2 phosphorylates in vitro. DAF-2 insulin-like receptor signaling stimulates DAF-16 S249 phosphorylation, suggesting DAF-2 activates PAR-1. DAF-2 also promotes PAR-1 expression by inhibiting DAF-16. PAR-1 knockdown, or DAF-16 S249A, prolong lifespan, whereas phosphomimetic DAF-16 S249D suppresses the longevity of daf-2 mutants. At low insulin signaling, DAF-16 proximity labeling highlights transcription factors, chromatin regulators, and DNA repair proteins. One interactor, the zinc finger/homeobox protein ZFH-2/ZFHX3, forms a complex with DAF-16 and prolongs lifespan. Our work provides entry points for hypothesis-driven studies of FOXO function and longevity."}],"day":"11","article_type":"original","scopus_import":"1","project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"_id":"23870BE8-32DE-11EA-91FC-C7463DDC885E","name":"Molecular mechanisms of neural circuit function","grant_number":"209504/A/17/Z"}],"citation":{"short":"M. Artan, H. Schön, M. de Bono, Nature Communications 16 (2025).","apa":"Artan, M., Schön, H., &#38; de Bono, M. (2025). Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>","chicago":"Artan, Murat, Hanna Schön, and Mario de Bono. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>.","ieee":"M. Artan, H. Schön, and M. de Bono, “Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","ama":"Artan M, Schön H, de Bono M. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>","mla":"Artan, Murat, et al. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>, vol. 16, 11355, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>.","ista":"Artan M, Schön H, de Bono M. 2025. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. Nature Communications. 16, 11355."},"publication_identifier":{"eissn":["2041-1723"]},"file":[{"success":1,"access_level":"open_access","date_updated":"2026-01-05T10:58:28Z","file_id":"20941","relation":"main_file","file_size":1642352,"creator":"dernst","checksum":"748e2e003b878b85b6048d51621d6aae","file_name":"2025_NatureComm_Artan.pdf","date_created":"2026-01-05T10:58:28Z","content_type":"application/pdf"}],"file_date_updated":"2026-01-05T10:58:28Z","language":[{"iso":"eng"}],"acknowledgement":"We thank de Bono lab members for helpful comments on the manuscript, and the Mass Spec Facility at the Max Perutz Labs, notably WeiQiang Chen and Markus Hartl, for invaluable discussions and comments on mass spec analyses of worm samples. All LC-MS/MS analyses were performed on instruments of the Vienna BioCenter Core Facilities (VBCF). Microscopy was supported by the Scientific Services Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF). We are grateful to Dr. Geraldine Seydoux (Johns Hopkins University) for worm strains and plasmids, and Dr. Seung-Jae V. Lee (KAIST) for RNAi clones. We are grateful to Ekaterina Lashmanova for designing the daf-16::TbID::mNG::3xFLAG knock-in construct and for her outstanding support in the lab. This work was supported by a Wellcome Investigator Award (209504/A/17/Z) to MdB and an ISTplus Fellowship to MA (Marie Sklodowska-Curie agreement No 754411).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version"},{"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","language":[{"iso":"eng"}],"acknowledgement":"We thank the referee for their suggestions and comments, which helped us improve the quality and clarity of the paper. JLGM and EV acknowledge the support from the Spanish Ministry of Science and Innovation/State Agency of Research (MCIN/AEI) under the grant PID2021-127289-NB-I00. ST acknowledges the funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. AJM acknowledges support from the Swedish National Space Agency (Career Grant 2023-00146) and from the Swedish Research Council (Project Grant 2022-04043). JLGM also sincerely thanks AMP for his careful final reading of this manuscript. This work has made use of data from the European Space Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by the Gaia Data Processing and Analysis Consortium (DPAC). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. We acknowledge the use of the public data products from RAVE (https://www.rave-survey.org), GALAH (https://galah-survey.org), APOGEE ((https://www.sdss.org) and LAMOST (http://www.lamost.org) surveys. This research has also made use of the SIMBAD database and the VizieR catalogue access tool, operated at CDS, Strasbourg, France, as well as the NASA Astrophysics Data System Bibliographic Services and the arXiv pre-print server operated by Cornell University. Computational analyses in this work relied extensively on the NumPy and SciPy libraries for numerical computing, matplotlib and seaborn for data visualization, and the Gala package for Galactic dynamics. This work also made use of Astropy, a community-developed core PYTHON package and an ecosystem of tools and resources for astronomy. We thank the developers and maintainers of these open-source resources for their invaluable contributions to the astronomical community.","file":[{"date_updated":"2026-01-05T11:06:16Z","access_level":"open_access","success":1,"creator":"dernst","file_size":11021467,"file_id":"20942","relation":"main_file","date_created":"2026-01-05T11:06:16Z","file_name":"2025_AstronomyAstrophysics_GrageraMas.pdf","checksum":"2fb4d5a1603043aa7931a31f2c180877","content_type":"application/pdf"}],"file_date_updated":"2026-01-05T11:06:16Z","citation":{"short":"J.L. Gragera-Más, S. Torres Rodriguez, A.J. Mustill, E. Villaver, Astronomy &#38; Astrophysics 704 (2025).","apa":"Gragera-Más, J. L., Torres Rodriguez, S., Mustill, A. J., &#38; Villaver, E. (2025). A kinematic history of stellar encounters with Beta Pictoris. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202555940\">https://doi.org/10.1051/0004-6361/202555940</a>","chicago":"Gragera-Más, J. L., Santiago Torres Rodriguez, A. J. Mustill, and E. Villaver. “A Kinematic History of Stellar Encounters with Beta Pictoris.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202555940\">https://doi.org/10.1051/0004-6361/202555940</a>.","ieee":"J. L. Gragera-Más, S. Torres Rodriguez, A. J. Mustill, and E. Villaver, “A kinematic history of stellar encounters with Beta Pictoris,” <i>Astronomy &#38; Astrophysics</i>, vol. 704. EDP Sciences, 2025.","ama":"Gragera-Más JL, Torres Rodriguez S, Mustill AJ, Villaver E. A kinematic history of stellar encounters with Beta Pictoris. <i>Astronomy &#38; Astrophysics</i>. 2025;704. doi:<a href=\"https://doi.org/10.1051/0004-6361/202555940\">10.1051/0004-6361/202555940</a>","mla":"Gragera-Más, J. L., et al. “A Kinematic History of Stellar Encounters with Beta Pictoris.” <i>Astronomy &#38; Astrophysics</i>, vol. 704, A237, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202555940\">10.1051/0004-6361/202555940</a>.","ista":"Gragera-Más JL, Torres Rodriguez S, Mustill AJ, Villaver E. 2025. A kinematic history of stellar encounters with Beta Pictoris. Astronomy &#38; Astrophysics. 704, A237."},"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"volume":704,"abstract":[{"lang":"eng","text":"Context. Beta Pictoris is an A-type star that hosts a complex planetary system with two massive gas giants and a prominent debris disc. Variable absorption lines in its stellar spectrum have been interpreted as signatures of exocomets – comet-like bodies transiting the star. Stellar flybys can gravitationally perturb objects in the outer comet reservoir, altering their orbits and potentially injecting them into the inner system, thereby triggering exocomet showers.\r\nAims. We assessed the contribution of stellar flybys to the observed exocomet activity by reconstructing the stellar encounter history of β Pictoris in the past and future.\r\nMethods. We used Gaia DR3 data, supplemented with radial velocities from complementary spectroscopic surveys, to compile a catalogue of stars currently within 80 pc of β Pictoris. Their orbits were integrated backwards and forwards in time in an axisymmetric Galactic potential (via the GALA package) to identify encounters within 2 pc of the system.\r\nResults. We identified 99 416 stars currently within 80 pc of β Pictoris with resolved kinematics. Among these, 49 stars (including the eight components of five binaries) encounter β Pictoris within 2 pc between –1.5 Myr and +2 Myr. For four of the binaries, the centre-of-mass trajectories also pass within 2 pc. We estimated the sample to be more than 60% complete within 0.5 Myr of today.\r\nConclusions. Despite β Pictoris being the eponym of its famous moving group, none of the identified encounters involved its moving group members; all are unrelated field stars. We found no encounter capable of shaping the observed disc structures, although stellar flybys may contribute to the long-term evolution of an Oort Cloud-like structure. Our catalogue constitutes the most complete reconstruction of the β Pictoris encounter history to date and provides a robust foundation for future dynamical simulations."}],"day":"01","article_type":"original","scopus_import":"1","ec_funded":1,"ddc":["520"],"publication":"Astronomy & Astrophysics","date_published":"2025-12-01T00:00:00Z","type":"journal_article","DOAJ_listed":"1","arxiv":1,"fulldoi":"https://doi.org/10.1051/0004-6361/202555940","department":[{"_id":"LiBu"}],"OA_type":"diamond","OA_place":"publisher","article_processing_charge":"No","month":"12","publication_status":"published","date_created":"2026-01-04T23:01:34Z","article_number":"A237","external_id":{"arxiv":["2510.02509"]},"PlanS_conform":"1","_id":"20930","doi":"10.1051/0004-6361/202555940","title":"A kinematic history of stellar encounters with Beta Pictoris","year":"2025","date_updated":"2026-02-16T12:15:07Z","has_accepted_license":"1","status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"EDP Sciences","intvolume":"       704","author":[{"first_name":"J. L.","full_name":"Gragera-Más, J. L.","last_name":"Gragera-Más"},{"id":"a8df4360-4328-11ee-8f1a-e502d0c83fc2","first_name":"Santiago","orcid":"0000-0002-3150-8988","last_name":"Torres Rodriguez","full_name":"Torres Rodriguez, Santiago"},{"first_name":"A. J.","full_name":"Mustill, A. J.","last_name":"Mustill"},{"first_name":"E.","last_name":"Villaver","full_name":"Villaver, E."}],"oa":1},{"fulldoi":"https://doi.org/10.1051/0004-6361/202556410","type":"journal_article","date_published":"2025-12-01T00:00:00Z","DOAJ_listed":"1","arxiv":1,"date_created":"2026-01-04T23:01:35Z","article_number":"A328","external_id":{"arxiv":["2507.11045"]},"OA_type":"diamond","department":[{"_id":"JoMa"}],"OA_place":"publisher","article_processing_charge":"No","month":"12","publication_status":"published","doi":"10.1051/0004-6361/202556410","date_updated":"2026-02-16T12:14:52Z","title":"A Lyman continuum analysis of ∼100 galaxies at z spec∼ 3 in the Abell 2744 cluster field","year":"2025","quality_controlled":"1","status":"public","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"20932","PlanS_conform":"1","publisher":"EDP Sciences","intvolume":"       704","oa":1,"author":[{"last_name":"Liu","full_name":"Liu, Y.","first_name":"Y."},{"last_name":"Mascia","full_name":"Mascia, Sara","first_name":"Sara","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29"},{"first_name":"L.","full_name":"Pentericci, L.","last_name":"Pentericci"},{"first_name":"P.","last_name":"Watson","full_name":"Watson, P."},{"first_name":"A.","full_name":"Alavi, A.","last_name":"Alavi"},{"first_name":"P.","full_name":"Bergamini, P.","last_name":"Bergamini"},{"last_name":"Bradač","full_name":"Bradač, M.","first_name":"M."},{"last_name":"Calabrò","full_name":"Calabrò, A.","first_name":"A."},{"last_name":"Glazebrook","full_name":"Glazebrook, K.","first_name":"K."},{"first_name":"A.","full_name":"Henry, A.","last_name":"Henry"},{"first_name":"M.","full_name":"Llerena, M.","last_name":"Llerena"},{"last_name":"Merlin","full_name":"Merlin, E.","first_name":"E."},{"first_name":"B.","last_name":"Metha","full_name":"Metha, B."},{"last_name":"Nanayakkara","full_name":"Nanayakkara, T.","first_name":"T."},{"full_name":"Napolitano, L.","last_name":"Napolitano","first_name":"L."},{"full_name":"Roy, N.","last_name":"Roy","first_name":"N."},{"full_name":"Siana, B.","last_name":"Siana","first_name":"B."},{"last_name":"Vanzella","full_name":"Vanzella, E.","first_name":"E."},{"first_name":"B.","last_name":"Vulcani","full_name":"Vulcani, B."},{"first_name":"X.","full_name":"Wang, X.","last_name":"Wang"}],"language":[{"iso":"eng"}],"acknowledgement":"We acknowledge support from the National Science Foundation of China – 12225301, INAF Large grant “Spectroscopic survey with JWST” jand from PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU, and Postgraduate Scholarship Program under the grant of China Scholarship Council. P.W. and B.V. acknowledge support from the INAF Mini Grant ‘1.05.24.07.01 RSN1: Spatially Resolved Near-IR Emission of Intermediate-Redshift Jellyfish Galaxies’ (PI Watson). We acknowledge A. Acebron, C. Grillo, and P. Rosati for their fundamental contribution to the strong lensing analysis and results. We also extend our gratitude to the JWST and HST teams for their efforts in designing, building, and operating these transformative missions.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","citation":{"chicago":"Liu, Y., Sara Mascia, L. Pentericci, P. Watson, A. Alavi, P. Bergamini, M. Bradač, et al. “A Lyman Continuum Analysis of ∼100 Galaxies at z Spec∼ 3 in the Abell 2744 Cluster Field.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202556410\">https://doi.org/10.1051/0004-6361/202556410</a>.","ieee":"Y. Liu <i>et al.</i>, “A Lyman continuum analysis of ∼100 galaxies at z spec∼ 3 in the Abell 2744 cluster field,” <i>Astronomy &#38; Astrophysics</i>, vol. 704. EDP Sciences, 2025.","short":"Y. Liu, S. Mascia, L. Pentericci, P. Watson, A. Alavi, P. Bergamini, M. Bradač, A. Calabrò, K. Glazebrook, A. Henry, M. Llerena, E. Merlin, B. Metha, T. Nanayakkara, L. Napolitano, N. Roy, B. Siana, E. Vanzella, B. Vulcani, X. Wang, Astronomy &#38; Astrophysics 704 (2025).","apa":"Liu, Y., Mascia, S., Pentericci, L., Watson, P., Alavi, A., Bergamini, P., … Wang, X. (2025). A Lyman continuum analysis of ∼100 galaxies at z spec∼ 3 in the Abell 2744 cluster field. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556410\">https://doi.org/10.1051/0004-6361/202556410</a>","mla":"Liu, Y., et al. “A Lyman Continuum Analysis of ∼100 Galaxies at z Spec∼ 3 in the Abell 2744 Cluster Field.” <i>Astronomy &#38; Astrophysics</i>, vol. 704, A328, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556410\">10.1051/0004-6361/202556410</a>.","ista":"Liu Y, Mascia S, Pentericci L, Watson P, Alavi A, Bergamini P, Bradač M, Calabrò A, Glazebrook K, Henry A, Llerena M, Merlin E, Metha B, Nanayakkara T, Napolitano L, Roy N, Siana B, Vanzella E, Vulcani B, Wang X. 2025. A Lyman continuum analysis of ∼100 galaxies at z spec∼ 3 in the Abell 2744 cluster field. Astronomy &#38; Astrophysics. 704, A328.","ama":"Liu Y, Mascia S, Pentericci L, et al. A Lyman continuum analysis of ∼100 galaxies at z spec∼ 3 in the Abell 2744 cluster field. <i>Astronomy &#38; Astrophysics</i>. 2025;704. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556410\">10.1051/0004-6361/202556410</a>"},"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"file":[{"content_type":"application/pdf","checksum":"3e6061f3c4bfb521b3333ea4913c241a","file_name":"2025_AstronomyAstrophysics_Liu.pdf","date_created":"2026-01-05T09:26:17Z","relation":"main_file","file_id":"20938","file_size":4642530,"creator":"dernst","success":1,"access_level":"open_access","date_updated":"2026-01-05T09:26:17Z"}],"file_date_updated":"2026-01-05T09:26:17Z","volume":704,"abstract":[{"lang":"eng","text":"Identifying Lyman continuum (LyC) leakers at intermediate redshifts is crucial for understanding the properties of cosmic reionizers because the opacity of the intergalactic medium (IGM) prevents the direct detection of LyC emission from sources during the Epoch of Reionization (EoR). In this study, we confirm two new LyC candidate leakers at z ∼ 3 in the Abell 2744 cluster field, with absolute escape fractions (fesc) of 0.83−0.80+0.15 and 0.74−0.70+0.23, respectively. The LyC emission was detected using HST/WFC3/F275W and F336W imaging. These two candidate leakers appear to be faint (MUV = −17.61 ± 0.06 and −18.22 ± 0.10), exhibit blue UV continuum slopes (β = −2.43 ± 0.05 and −1.92 ± 0.09), have low masses (M★ ∼ 107.51 ± 0.03 and 107.17 ± 0.15 M⊙) and Lyα equivalent widths of 90 ± 3 Å and 28 ± 12 Å, respectively. These two LyC candidate leakers were detected in a catalog of 91 spectroscopically confirmed sources using public spectra from the JWST and/or MUSE. We also analyzed properties that were proposed as indirect indicators of LyC emission, such as Lyα, the O32 ratio, and M★. We created a galaxy subsample that was selected according to these properties, stacked the LyC observations of this subsample, and assessed the limits of the escape fractions in the stacks. We aim to enhance our understanding of LyC escape mechanisms and improve our predictions of the LyC fesc during the EoR by analyzing the individual candidates and the stacks in the context of the currently limited sample of known LyC leakers at z ∼ 3."}],"day":"01","article_type":"original","scopus_import":"1","ddc":["520"],"publication":"Astronomy & Astrophysics"},{"publication":"Transactions on Machine Learning Research","ddc":["000"],"article_type":"original","day":"18","scopus_import":"1","alternative_title":["TMLR"],"abstract":[{"lang":"eng","text":" Supervised learning for causal discovery from observational data often achieves competitive performance despite seemingly avoiding the explicit assumptions that traditional methods require for identifiability. In this work, we analyze CSIvA (Ke et al., 2023) on bivariate causal models, a transformer architecture for amortized inference promising to train on synthetic data and transfer to real ones. First, we bridge the gap with identifiability theory, showing that the training distribution implicitly defines a prior on the causal model of the test observations: consistent with classical approaches, good performance is achieved when we have a good prior on the test data, and the underlying model is identifiable. Second, we find that CSIvA can not generalize to classes of causal models unseen during training: to overcome this limitation, we theoretically and empirically analyze \\textit{when} training CSIvA on datasets generated by multiple identifiable causal models with different structural assumptions improves its generalization at test time. Overall, we find that amortized causal discovery still adheres to identifiability theory, violating the previous hypothesis from Lopez-Paz et al. (2015) that supervised learning methods could overcome its restrictions."}],"file_date_updated":"2026-01-05T09:51:28Z","file":[{"success":1,"access_level":"open_access","date_updated":"2026-01-05T09:51:28Z","relation":"main_file","file_id":"20939","file_size":1030280,"creator":"dernst","checksum":"968c471bb1f682cf823b2d4cadea8a3f","file_name":"2025_PMLR_Montagna.pdf","date_created":"2026-01-05T09:51:28Z","content_type":"application/pdf"}],"publication_identifier":{"eissn":["2835-8856"]},"citation":{"apa":"Montagna, F., Cairney-Leeming, M. T., Sridhar, D., &#38; Locatello, F. (2025). Demystifying amortized causal discovery with transformers. <i>Transactions on Machine Learning Research</i>. ML Research Press.","short":"F. Montagna, M.T. Cairney-Leeming, D. Sridhar, F. Locatello, Transactions on Machine Learning Research (2025).","chicago":"Montagna, Francesco, Maximilian T Cairney-Leeming, Dhanya Sridhar, and Francesco Locatello. “Demystifying Amortized Causal Discovery with Transformers.” <i>Transactions on Machine Learning Research</i>. ML Research Press, 2025.","ieee":"F. Montagna, M. T. Cairney-Leeming, D. Sridhar, and F. Locatello, “Demystifying amortized causal discovery with transformers,” <i>Transactions on Machine Learning Research</i>. ML Research Press, 2025.","ama":"Montagna F, Cairney-Leeming MT, Sridhar D, Locatello F. Demystifying amortized causal discovery with transformers. <i>Transactions on Machine Learning Research</i>. 2025.","ista":"Montagna F, Cairney-Leeming MT, Sridhar D, Locatello F. 2025. Demystifying amortized causal discovery with transformers. Transactions on Machine Learning Research.","mla":"Montagna, Francesco, et al. “Demystifying Amortized Causal Discovery with Transformers.” <i>Transactions on Machine Learning Research</i>, ML Research Press, 2025."},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Montagna","full_name":"Montagna, Francesco","id":"353afc8e-19f4-11f0-9db9-811f1723c83f","first_name":"Francesco"},{"id":"2214a80c-31f8-11ee-a48d-cf52cc58759b","first_name":"Maximilian T","last_name":"Cairney-Leeming","full_name":"Cairney-Leeming, Maximilian T"},{"first_name":"Dhanya","last_name":"Sridhar","full_name":"Sridhar, Dhanya"},{"first_name":"Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683","last_name":"Locatello","full_name":"Locatello, Francesco"}],"corr_author":"1","publisher":"ML Research Press","PlanS_conform":"1","_id":"20934","quality_controlled":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","date_updated":"2026-01-05T09:54:59Z","year":"2025","title":"Demystifying amortized causal discovery with transformers","publication_status":"published","OA_type":"gold","department":[{"_id":"FrLo"}],"OA_place":"publisher","article_processing_charge":"No","month":"12","external_id":{"arxiv":["2405.16924"]},"date_created":"2026-01-04T23:01:35Z","related_material":{"link":[{"relation":"software","url":"https://github.com/francescomontagna/learning-to-induce.git"}]},"arxiv":1,"date_published":"2025-12-18T00:00:00Z","type":"journal_article"},{"PlanS_conform":"1","_id":"20960","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","status":"public","quality_controlled":"1","doi":"10.1002/anie.202505273","title":"Interfacing B‐DNA and DNA mimic foldamers","year":"2025","date_updated":"2026-01-19T11:07:53Z","extern":"1","author":[{"first_name":"Manuel","full_name":"Loos, Manuel","last_name":"Loos"},{"first_name":"Felix","full_name":"Xu, Felix","last_name":"Xu"},{"last_name":"Mandal","full_name":"Mandal, Pradeep K","first_name":"Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","orcid":"0000-0001-5996-956X"},{"full_name":"Chakrabortty, Tulika","last_name":"Chakrabortty","first_name":"Tulika"},{"first_name":"Céline","last_name":"Douat","full_name":"Douat, Céline"},{"first_name":"David B.","full_name":"Konrad, David B.","last_name":"Konrad"},{"first_name":"Melis","last_name":"Cabbar","full_name":"Cabbar, Melis"},{"last_name":"Singer","full_name":"Singer, Johannes","first_name":"Johannes"},{"first_name":"Valentina","full_name":"Corvaglia, Valentina","last_name":"Corvaglia"},{"first_name":"Thomas","last_name":"Carell","full_name":"Carell, Thomas"},{"full_name":"Huc, Ivan","last_name":"Huc","first_name":"Ivan"}],"oa":1,"intvolume":"        64","publisher":"Wiley","pmid":1,"date_published":"2025-07-28T00:00:00Z","type":"journal_article","fulldoi":"https://doi.org/10.1002/anie.202505273","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/anie.202505273"}],"publication_status":"published","OA_type":"hybrid","month":"07","article_processing_charge":"Yes (in subscription journal)","OA_place":"publisher","article_number":"e202505273","external_id":{"pmid":["40346004"]},"date_created":"2026-01-08T07:04:48Z","day":"28","article_type":"original","scopus_import":"1","volume":64,"abstract":[{"lang":"eng","text":"A linker unit was designed and synthesized that can serve both as a hairpin turn in a DNA duplex and anchor point for an aromatic helical foldamer mimicking the shape and surface properties of B‐DNA. Methods were developed to synthesize natural/non‐natural chimeric molecules combining foldamer and DNA segments. The ability of the linker to position the foldamer helix and the duplex DNA so that their rims and grooves are in register, despite their completely different chemical nature, was demonstrated using single crystal X‐ray diffraction, circular dichroism and molecular models. Bio‐layer interferometry confirmed that artificial hairpin DNA duplexes keep their ability to bind to DNA binding proteins. The chimeric molecules may pave the way to competitive inhibitors of protein‐DNA interactions involving sequence‐selective DNA‐binding proteins."}],"ddc":["540"],"publication":"Angewandte Chemie International Edition","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","issue":"31","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"citation":{"short":"M. Loos, F. Xu, P.K. Mandal, T. Chakrabortty, C. Douat, D.B. Konrad, M. Cabbar, J. Singer, V. Corvaglia, T. Carell, I. Huc, Angewandte Chemie International Edition 64 (2025).","apa":"Loos, M., Xu, F., Mandal, P. K., Chakrabortty, T., Douat, C., Konrad, D. B., … Huc, I. (2025). Interfacing B‐DNA and DNA mimic foldamers. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202505273\">https://doi.org/10.1002/anie.202505273</a>","ieee":"M. Loos <i>et al.</i>, “Interfacing B‐DNA and DNA mimic foldamers,” <i>Angewandte Chemie International Edition</i>, vol. 64, no. 31. Wiley, 2025.","chicago":"Loos, Manuel, Felix Xu, Pradeep K Mandal, Tulika Chakrabortty, Céline Douat, David B. Konrad, Melis Cabbar, et al. “Interfacing B‐DNA and DNA Mimic Foldamers.” <i>Angewandte Chemie International Edition</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/anie.202505273\">https://doi.org/10.1002/anie.202505273</a>.","ama":"Loos M, Xu F, Mandal PK, et al. Interfacing B‐DNA and DNA mimic foldamers. <i>Angewandte Chemie International Edition</i>. 2025;64(31). doi:<a href=\"https://doi.org/10.1002/anie.202505273\">10.1002/anie.202505273</a>","mla":"Loos, Manuel, et al. “Interfacing B‐DNA and DNA Mimic Foldamers.” <i>Angewandte Chemie International Edition</i>, vol. 64, no. 31, e202505273, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/anie.202505273\">10.1002/anie.202505273</a>.","ista":"Loos M, Xu F, Mandal PK, Chakrabortty T, Douat C, Konrad DB, Cabbar M, Singer J, Corvaglia V, Carell T, Huc I. 2025. Interfacing B‐DNA and DNA mimic foldamers. Angewandte Chemie International Edition. 64(31), e202505273."}},{"publication":"Applied Physics Letters","scopus_import":"1","day":"22","article_type":"original","abstract":[{"text":"We present an experimental demonstration of an impedance-engineered Josephson parametric amplifier (IEJPA) fabricated in a single-step lithography process. Impedance-engineering is implemented using a lumped-element series LC circuit. We use a simpler lithography process where the entire device—impedance transformer and Josephson parametric amplifier (JPA)—is patterned in a single electron beam lithography step, followed by a double-angle Dolan-bridge technique for Al–AlOx–Al deposition. We observe amplification with 18 dB gain over a wide 400 MHz bandwidth centered around 5.3 GHz with added noise approaching the quantum limit, and a saturation power of −114 dBm. To accurately explain our experimental results, we extend existing theories for IEJPAs to incorporate the full sine nonlinearity of both the JPA and the transformer. Our work provides a route to simpler realization of broadband JPAs and a theoretical foundation for a regime of JPA operation that has been less explored in literature.","lang":"eng"}],"volume":127,"publication_identifier":{"issn":["0003-6951"],"eissn":["1077-3118"]},"citation":{"ama":"Patel L, Hawaldar S, Panikkar A, Shankar A, Suri B. Impedance-engineered Josephson parametric amplifier with single-step lithography. <i>Applied Physics Letters</i>. 2025;127(25). doi:<a href=\"https://doi.org/10.1063/5.0290636\">10.1063/5.0290636</a>","ista":"Patel L, Hawaldar S, Panikkar A, Shankar A, Suri B. 2025. Impedance-engineered Josephson parametric amplifier with single-step lithography. Applied Physics Letters. 127(25), 254001.","mla":"Patel, Lipi, et al. “Impedance-Engineered Josephson Parametric Amplifier with Single-Step Lithography.” <i>Applied Physics Letters</i>, vol. 127, no. 25, 254001, AIP Publishing, 2025, doi:<a href=\"https://doi.org/10.1063/5.0290636\">10.1063/5.0290636</a>.","apa":"Patel, L., Hawaldar, S., Panikkar, A., Shankar, A., &#38; Suri, B. (2025). Impedance-engineered Josephson parametric amplifier with single-step lithography. <i>Applied Physics Letters</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0290636\">https://doi.org/10.1063/5.0290636</a>","short":"L. Patel, S. Hawaldar, A. Panikkar, A. Shankar, B. Suri, Applied Physics Letters 127 (2025).","ieee":"L. Patel, S. Hawaldar, A. Panikkar, A. Shankar, and B. Suri, “Impedance-engineered Josephson parametric amplifier with single-step lithography,” <i>Applied Physics Letters</i>, vol. 127, no. 25. AIP Publishing, 2025.","chicago":"Patel, Lipi, Samarth Hawaldar, Aditya Panikkar, Athreya Shankar, and Baladitya Suri. “Impedance-Engineered Josephson Parametric Amplifier with Single-Step Lithography.” <i>Applied Physics Letters</i>. AIP Publishing, 2025. <a href=\"https://doi.org/10.1063/5.0290636\">https://doi.org/10.1063/5.0290636</a>."},"acknowledgement":"The authors acknowledge receiving support from the Space Technology Cell at IISc and ISRO through the project STC-0444(2022) and the Ministry of Electronics and Information Technology of the Government of India, under the centre of Excellence of Quantum Technology at the Indian Institute of Science, as well as the office of Principle Scientific Advisor, Government of India. S.H. and A.P. acknowledge the support of the Kishore Vaigyanik Protsahan Yojana (KVPY). A.S. acknowledges the support of a New Faculty Initiation Grant (NFIG) from IIT Madras.","issue":"25","language":[{"iso":"eng"}],"oa_version":"Preprint","author":[{"last_name":"Patel","full_name":"Patel, Lipi","first_name":"Lipi"},{"last_name":"Hawaldar","full_name":"Hawaldar, Samarth","id":"221708e1-1ff6-11ee-9fa6-85146607433e","first_name":"Samarth","orcid":"0000-0002-1965-4309"},{"first_name":"Aditya","last_name":"Panikkar","full_name":"Panikkar, Aditya"},{"first_name":"Athreya","full_name":"Shankar, Athreya","last_name":"Shankar"},{"last_name":"Suri","full_name":"Suri, Baladitya","first_name":"Baladitya"}],"oa":1,"publisher":"AIP Publishing","intvolume":"       127","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","quality_controlled":"1","year":"2025","title":"Impedance-engineered Josephson parametric amplifier with single-step lithography","date_updated":"2026-01-12T09:57:53Z","doi":"10.1063/5.0290636","_id":"20976","external_id":{"arxiv":["2507.09298"]},"article_number":"254001","date_created":"2026-01-11T23:01:34Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2507.09298"}],"publication_status":"published","month":"12","article_processing_charge":"No","OA_place":"repository","OA_type":"green","department":[{"_id":"JoFi"}],"fulldoi":"https://doi.org/10.1063/5.0290636","arxiv":1,"type":"journal_article","date_published":"2025-12-22T00:00:00Z"},{"quality_controlled":"1","has_accepted_license":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1038/s41467-025-66562-6","title":"Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans","date_updated":"2026-01-12T09:31:56Z","year":"2025","_id":"20977","author":[{"full_name":"Maslarova, Anna","last_name":"Maslarova","first_name":"Anna"},{"first_name":"Jiyun N.","last_name":"Shin","full_name":"Shin, Jiyun N."},{"last_name":"Navas Olivé","full_name":"Navas Olivé, Andrea C","first_name":"Andrea C","id":"739d26c9-52e8-11ee-8d72-f14d3893b4ce","orcid":"0000-0002-9280-8597"},{"full_name":"Vöröslakos, Mihály","last_name":"Vöröslakos","first_name":"Mihály"},{"full_name":"Hamer, Hajo","last_name":"Hamer","first_name":"Hajo"},{"first_name":"Arnd","last_name":"Doerfler","full_name":"Doerfler, Arnd"},{"last_name":"Henin","full_name":"Henin, Simon","first_name":"Simon"},{"first_name":"György","full_name":"Buzsáki, György","last_name":"Buzsáki"},{"full_name":"Liu, Anli","last_name":"Liu","first_name":"Anli"}],"oa":1,"publisher":"Springer Nature","intvolume":"        16","fulldoi":"https://doi.org/10.1038/s41467-025-66562-6","pmid":1,"date_published":"2025-12-30T00:00:00Z","type":"journal_article","DOAJ_listed":"1","article_number":"11636","external_id":{"pmid":["39975118"]},"date_created":"2026-01-11T23:01:35Z","publication_status":"published","department":[{"_id":"PeJo"}],"OA_type":"gold","OA_place":"publisher","article_processing_charge":"Yes","month":"12","day":"30","article_type":"original","scopus_import":"1","volume":16,"abstract":[{"text":"Hippocampal sharp-wave ripples (SPW-Rs) are high-frequency oscillations critical for memory consolidation. Despite extensive characterization in rodents, their detection in humans is limited by coarse spatial sampling, interictal epileptiform discharges (IEDs), and a lack of consensus on human ripple localization and morphology. Here, we demonstrate that mouse and human hippocampal ripples share spatial, spectral and temporal features, which are clearly distinct from IEDs. In recordings from male APP/PS1 mice, SPW-Rs were distinguishable from IEDs by multiple criteria. Hippocampal ripples recorded during NREM sleep in female and male surgical epilepsy patients exhibited similar narrowband frequency peaks and multiple ripple cycles in the CA1 and subiculum regions. Conversely, IEDs showed a broad spatial extent and wide-band frequency power. We developed a semi-automated, ripple curation toolbox (ripmap) to separate event waveforms by low-dimensional embedding to reduce false-positive rate in selected ripple channels. Our approach improves ripple detection and provides a firm foundation for future human memory research.","lang":"eng"}],"project":[{"_id":"9B861AAC-BA93-11EA-9121-9846C619BF3A","name":"NOMIS Fellowship Program"}],"ddc":["570"],"publication":"Nature Communications","acknowledgement":"We thank Karl Rössler and Sebastian Brandner for the human SEEG implantations; Katja Kobow for providing the histopathological findings of the patients; Jay Jeschke for help with human electrode localization; Esha Brahmbhatt and Deren Aykan for help with animal habituation; Mursel Karadas for the rodent treadmill design; Nicholas Paleologos, Noam Nitzan, Michael D Hadler and Samuel McKenzie for rating events in a human ripple survey included in a previous version of the manuscript; Nicholas Paleologos for sharing NYU iEEG data for validating UMAP parameters; Julio Esparza for help on the topological analysis through discussions; Thomas Hainmüller, Yiyao Zhang and Mursel Karadas for feedback on the manuscript. We would like to acknowledge Corticale SRL (Genoa, Italy) for providing the SiNAPS probes, and NeuroNexus (Ann Arbor, MI) for their contribution of the data acquisition system and Radiens software. We further acknowledge both Corticale and NeuroNexus for training and support making this research possible. This work was supported by the German Research Foundation (DFG; Walter Benjamin Fellowship MA 10301/1-1, A.M.), NYU Langone Health Finding a Cure for Epilepsy and Seizures (FACES, A.M.), the NOMIS Fellowship (A.N.-O.), the National Institutes of Health (R01NS127954, K23NS104252, A.L.; MH122391, U19NS107616, R01MH139216 G.B.,), and the NYU Department of Neurology (A.L.).","language":[{"iso":"eng"}],"tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"oa_version":"Published Version","publication_identifier":{"eissn":["2041-1723"]},"citation":{"ama":"Maslarova A, Shin JN, Navas Olivé AC, et al. Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-66562-6\">10.1038/s41467-025-66562-6</a>","ista":"Maslarova A, Shin JN, Navas Olivé AC, Vöröslakos M, Hamer H, Doerfler A, Henin S, Buzsáki G, Liu A. 2025. Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans. Nature Communications. 16, 11636.","mla":"Maslarova, Anna, et al. “Spatiotemporal Patterns Differentiate Hippocampal Sharp-Wave Ripples from Interictal Epileptiform Discharges in Mice and Humans.” <i>Nature Communications</i>, vol. 16, 11636, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-66562-6\">10.1038/s41467-025-66562-6</a>.","apa":"Maslarova, A., Shin, J. N., Navas Olivé, A. C., Vöröslakos, M., Hamer, H., Doerfler, A., … Liu, A. (2025). Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-66562-6\">https://doi.org/10.1038/s41467-025-66562-6</a>","short":"A. Maslarova, J.N. Shin, A.C. Navas Olivé, M. Vöröslakos, H. Hamer, A. Doerfler, S. Henin, G. Buzsáki, A. Liu, Nature Communications 16 (2025).","ieee":"A. Maslarova <i>et al.</i>, “Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","chicago":"Maslarova, Anna, Jiyun N. Shin, Andrea C Navas Olivé, Mihály Vöröslakos, Hajo Hamer, Arnd Doerfler, Simon Henin, György Buzsáki, and Anli Liu. “Spatiotemporal Patterns Differentiate Hippocampal Sharp-Wave Ripples from Interictal Epileptiform Discharges in Mice and Humans.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-66562-6\">https://doi.org/10.1038/s41467-025-66562-6</a>."},"file_date_updated":"2026-01-12T09:30:15Z","file":[{"date_updated":"2026-01-12T09:30:15Z","success":1,"access_level":"open_access","creator":"dernst","file_id":"20978","relation":"main_file","file_size":7629997,"date_created":"2026-01-12T09:30:15Z","checksum":"a8a1670e197484382e087be60f643945","file_name":"2025_NatureComm_Maslarova.pdf","content_type":"application/pdf"}]},{"author":[{"full_name":"Kulich, Ivan","last_name":"Kulich","first_name":"Ivan","id":"57a1567c-8314-11eb-9063-c9ddc3451a54"},{"first_name":"Denisa","last_name":"Oulehlová","full_name":"Oulehlová, Denisa"},{"first_name":"Dmitrii","id":"60466724-5355-11ee-ae5a-fa55e8f99c3d","full_name":"Vladimirtsev, Dmitrii","last_name":"Vladimirtsev"},{"first_name":"Minxia","id":"5c243f41-03f3-11ec-841c-96faf48a7ef9","full_name":"Zou, Minxia","last_name":"Zou"},{"first_name":"Edita","last_name":"Lileikyte","full_name":"Lileikyte, Edita"},{"first_name":"Alexey","last_name":"Bondar","full_name":"Bondar, Alexey"},{"last_name":"Kulichová","full_name":"Kulichová, Katarína","first_name":"Katarína"},{"first_name":"Martin","last_name":"Janda","full_name":"Janda, Martin"},{"first_name":"Oksana","last_name":"Iakovenko","full_name":"Iakovenko, Oksana"},{"last_name":"Neubergerová","full_name":"Neubergerová, Michaela","first_name":"Michaela"},{"first_name":"Tanja","last_name":"Studtrucker","full_name":"Studtrucker, Tanja"},{"first_name":"Roman","last_name":"Pleskot","full_name":"Pleskot, Roman"},{"first_name":"Petra","full_name":"Dietrich, Petra","last_name":"Dietrich"},{"full_name":"Fendrych, Matyas","last_name":"Fendrych","orcid":"0000-0002-9767-8699","first_name":"Matyas","id":"43905548-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-8302-7596","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","last_name":"Friml"}],"corr_author":"1","oa":1,"publication":"bioRxiv","status":"public","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","day":"16","date_updated":"2026-04-07T11:41:43Z","title":"Armadillo repeat only proteins are required for the function of plant CNGC channels","year":"2025","abstract":[{"text":"Plant cells respond to a wide range of stimuli through intracellular calcium (Ca2+) signaling. Cyclic nucleotide-gated channels (CNGCs) are a major class of plant Ca2+ channels, with 20 homologs in Arabidopsis. These tetrameric plasma membrane proteins act downstream of diverse signals, such as phytohormones, extracellular damage, cell wall integrity or temperature. Here, we identify a class of plant-specific proteins, Armadillo Repeat Only (ARO), as essential regulators of possibly all plant CNGCs. Abrogation of functional sporophytic AROs results in a phenotypic pattern strongly reminiscent of CNGC dysfunction, including defects in root gravitropism, root hair growth and morphology, stomatal movement, and responses to extracellular ATP and the phytohormone auxin. aro2/3/4 mutants are fully resistant to the toxic effects caused by overexpression of CNGCs. AROs colocalize and physically interact with multiple CNGCs and modulate CNGC-dependent currents in Xenopus oocytes. Structural modeling and site-directed mutagenesis reveal AROs tetramer formation surrounding the CNGC channel, interacting via its IQ domain. Taken together, plant CNGC channels don’t act alone, but in a larger complex - channelosome, first of a kind in plants.","lang":"eng"}],"doi":"10.1101/2025.01.06.631460","_id":"20982","date_created":"2026-01-13T14:07:58Z","citation":{"chicago":"Kulich, Ivan, Denisa Oulehlová, Dmitrii Vladimirtsev, Minxia Zou, Edita Lileikyte, Alexey Bondar, Katarína Kulichová, et al. “Armadillo Repeat Only Proteins Are Required for the Function of Plant CNGC Channels.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.01.06.631460\">https://doi.org/10.1101/2025.01.06.631460</a>.","ieee":"I. Kulich <i>et al.</i>, “Armadillo repeat only proteins are required for the function of plant CNGC channels,” <i>bioRxiv</i>. .","apa":"Kulich, I., Oulehlová, D., Vladimirtsev, D., Zou, M., Lileikyte, E., Bondar, A., … Friml, J. (n.d.). Armadillo repeat only proteins are required for the function of plant CNGC channels. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.01.06.631460\">https://doi.org/10.1101/2025.01.06.631460</a>","short":"I. Kulich, D. Oulehlová, D. Vladimirtsev, M. Zou, E. Lileikyte, A. Bondar, K. Kulichová, M. Janda, O. Iakovenko, M. Neubergerová, T. Studtrucker, R. Pleskot, P. Dietrich, M. Fendrych, J. Friml, BioRxiv (n.d.).","ista":"Kulich I, Oulehlová D, Vladimirtsev D, Zou M, Lileikyte E, Bondar A, Kulichová K, Janda M, Iakovenko O, Neubergerová M, Studtrucker T, Pleskot R, Dietrich P, Fendrych M, Friml J. Armadillo repeat only proteins are required for the function of plant CNGC channels. bioRxiv, <a href=\"https://doi.org/10.1101/2025.01.06.631460\">10.1101/2025.01.06.631460</a>.","mla":"Kulich, Ivan, et al. “Armadillo Repeat Only Proteins Are Required for the Function of Plant CNGC Channels.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.01.06.631460\">10.1101/2025.01.06.631460</a>.","ama":"Kulich I, Oulehlová D, Vladimirtsev D, et al. Armadillo repeat only proteins are required for the function of plant CNGC channels. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.01.06.631460\">10.1101/2025.01.06.631460</a>"},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.01.06.631460"}],"publication_status":"draft","article_processing_charge":"No","OA_place":"repository","month":"05","department":[{"_id":"JiFr"}],"acknowledgement":"This project was supported by the Czech Science Foundation grant Nr. 25-16449S and by European\r\nUnion, Horizon Europe, project MOLIPEC, ID 101087030. Computational resources used for structural\r\nmodeling were provided by the e-INFRA CZ project (ID:90254), supported by the Ministry of Education,\r\nYouth and Sports of the Czech Republic. Part of the work was carried out with the support of a Growth\r\nFacility (BC Core Facilities; IPMB BC CAS). X. laevis oocytes were kindly provided by C. Korbmacher on\r\na regular basis (FAU Erlangen-Nürnberg). MF received support from the European Research Council\r\n(Grant 480 No. 101125499). We acknowledge the core facility LMH, the BC CAS supported by the MEYS\r\nCR (LM 2023050 Czech-BioImaging). DO received support from the Czech Science Foundation grant Nr.\r\n24-12107S\r\n","fulldoi":"https://doi.org/10.1101/2025.01.06.631460","language":[{"iso":"eng"}],"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"20964"}]},"oa_version":"Preprint","type":"preprint","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"date_published":"2025-05-16T00:00:00Z"},{"oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"acknowledgement":"This work is a part of projects VAMOS that has received fund-ing from the European Research Council (ERC), grant agreementNo 101020093 and the Austrian Science Fund (FWF) SFB projectSpyCoDe F8502.We thank anonymous reviewers for pointing us to related work [ 3] and for their valuable suggestions that improved this paper.","file":[{"success":1,"access_level":"open_access","date_updated":"2026-01-21T07:34:58Z","file_id":"21024","relation":"main_file","file_size":1241912,"creator":"dernst","checksum":"615ffddab6c7285158c2953acec6fa6f","file_name":"2025_CCS_HenzingerT.pdf","date_created":"2026-01-21T07:34:58Z","content_type":"application/pdf"}],"file_date_updated":"2026-01-21T07:34:58Z","citation":{"ama":"Henzinger TA, Karimi M, Thejaswini KS. Privacy-preserving runtime verification. In: <i>Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security</i>. Association for Computing Machinery; 2025:2774-2787. doi:<a href=\"https://doi.org/10.1145/3719027.3765137\">10.1145/3719027.3765137</a>","ista":"Henzinger TA, Karimi M, Thejaswini KS. 2025. Privacy-preserving runtime verification. Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security. CCS: Conference on Computer and Communications Security, 2774–2787.","mla":"Henzinger, Thomas A., et al. “Privacy-Preserving Runtime Verification.” <i>Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security</i>, Association for Computing Machinery, 2025, pp. 2774–87, doi:<a href=\"https://doi.org/10.1145/3719027.3765137\">10.1145/3719027.3765137</a>.","apa":"Henzinger, T. A., Karimi, M., &#38; Thejaswini, K. S. (2025). Privacy-preserving runtime verification. In <i>Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security</i> (pp. 2774–2787). Taipei, Taiwan: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3719027.3765137\">https://doi.org/10.1145/3719027.3765137</a>","short":"T.A. Henzinger, M. Karimi, K.S. Thejaswini, in:, Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security, Association for Computing Machinery, 2025, pp. 2774–2787.","chicago":"Henzinger, Thomas A, Mahyar Karimi, and K. S. Thejaswini. “Privacy-Preserving Runtime Verification.” In <i>Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security</i>, 2774–87. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3719027.3765137\">https://doi.org/10.1145/3719027.3765137</a>.","ieee":"T. A. Henzinger, M. Karimi, and K. S. Thejaswini, “Privacy-preserving runtime verification,” in <i>Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security</i>, Taipei, Taiwan, 2025, pp. 2774–2787."},"publication_identifier":{"isbn":["9798400715259"]},"project":[{"call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"},{"grant_number":"F8502","name":"Interface Theory for Security and Privacy","_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e"}],"abstract":[{"lang":"eng","text":"Runtime verification offers scalable solutions to improve the safety and reliability of systems. However, systems that require verification or monitoring by a third party to ensure compliance with a specification might contain sensitive information, causing privacy concerns when usual runtime verification approaches are used. Privacy is compromised if protected information about the system, or sensitive data that is processed by the system, is revealed. In addition, revealing the specification being monitored may undermine the essence of third-party verification.\r\nIn this work, we propose two novel protocols for the privacy-preserving runtime verification of systems against formal sequential specifications. In our first protocol, the monitor verifies whether the system satisfies the specification without learning anything else, though both parties are aware of the specification. Our second protocol ensures that the system remains oblivious to the monitored specification, while the monitor learns only whether the system satisfies the specification and nothing more. Our protocols adapt and improve existing techniques used in cryptography, and more specifically, multi-party computation.\r\nThe sequential specification defines the observation step of the monitor, whose granularity depends on the situation (e.g., banks may be monitored on a daily basis). Our protocols exchange a single message per observation step, after an initialisation phase. This design minimises communication overhead, enabling relatively lightweight privacy-preserving monitoring. We implement our approach for monitoring specifications described by register automata and evaluate it experimentally."}],"scopus_import":"1","day":"22","ec_funded":1,"ddc":["000"],"publication":"Proceedings of the 2025 ACM SIGSAC Conference on Computer and Communications Security","page":"2774-2787","type":"conference","date_published":"2025-11-22T00:00:00Z","arxiv":1,"related_material":{"record":[{"relation":"dissertation_contains","id":"21401","status":"public"}]},"fulldoi":"https://doi.org/10.1145/3719027.3765137","month":"11","OA_place":"publisher","article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","department":[{"_id":"ToHe"},{"_id":"GradSch"}],"publication_status":"published","date_created":"2026-01-20T10:17:10Z","conference":{"name":"CCS: Conference on Computer and Communications Security","end_date":"2025-10-17","start_date":"2025-10-13","location":"Taipei, Taiwan"},"external_id":{"arxiv":["2505.09276"]},"_id":"21020","year":"2025","date_updated":"2026-03-13T13:37:19Z","title":"Privacy-preserving runtime verification","doi":"10.1145/3719027.3765137","quality_controlled":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","publisher":"Association for Computing Machinery","corr_author":"1","oa":1,"author":[{"first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2985-7724","last_name":"Henzinger","full_name":"Henzinger, Thomas A"},{"orcid":"0009-0005-0820-1696","first_name":"Mahyar","id":"6e5417ba-5355-11ee-ae5a-94c2e510b26b","full_name":"Karimi, Mahyar","last_name":"Karimi"},{"full_name":"Thejaswini, K. S.","last_name":"Thejaswini","id":"3807fb92-fdc1-11ee-bb4a-b4d8a431c753","first_name":"K. S."}]}]