[{"day":"19","publication_status":"published","article_number":"e1005974","language":[{"iso":"eng"}],"file":[{"file_id":"5067","date_updated":"2020-07-14T12:44:41Z","creator":"system","access_level":"open_access","date_created":"2018-12-12T10:14:17Z","file_size":6273249,"content_type":"application/pdf","checksum":"53d22b2b39e5adc243d34f18b2615a85","relation":"main_file","file_name":"IST-2016-705-v1+1_journal.pgen.1005974.PDF"}],"publication":"PLoS Genetics","file_date_updated":"2020-07-14T12:44:41Z","date_published":"2016-04-19T00:00:00Z","oa":1,"doi":"10.1371/journal.pgen.1005974","date_created":"2018-12-11T11:50:56Z","pubrep_id":"705","citation":{"short":"A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, M. Ackermann, PLoS Genetics 12 (2016).","ama":"Boehm A, Arnoldini M, Bergmiller T, Röösli T, Bigosch C, Ackermann M. Genetic manipulation of glycogen allocation affects replicative lifespan in E coli. PLoS Genetics. 2016;12(4). doi:10.1371/journal.pgen.1005974","apa":"Boehm, A., Arnoldini, M., Bergmiller, T., Röösli, T., Bigosch, C., & Ackermann, M. (2016). Genetic manipulation of glycogen allocation affects replicative lifespan in E coli. PLoS Genetics. Public Library of Science. https://doi.org/10.1371/journal.pgen.1005974","mla":"Boehm, Alex, et al. “Genetic Manipulation of Glycogen Allocation Affects Replicative Lifespan in E Coli.” PLoS Genetics, vol. 12, no. 4, e1005974, Public Library of Science, 2016, doi:10.1371/journal.pgen.1005974.","ista":"Boehm A, Arnoldini M, Bergmiller T, Röösli T, Bigosch C, Ackermann M. 2016. Genetic manipulation of glycogen allocation affects replicative lifespan in E coli. PLoS Genetics. 12(4), e1005974.","chicago":"Boehm, Alex, Markus Arnoldini, Tobias Bergmiller, Thomas Röösli, Colette Bigosch, and Martin Ackermann. “Genetic Manipulation of Glycogen Allocation Affects Replicative Lifespan in E Coli.” PLoS Genetics. Public Library of Science, 2016. https://doi.org/10.1371/journal.pgen.1005974.","ieee":"A. Boehm, M. Arnoldini, T. Bergmiller, T. Röösli, C. Bigosch, and M. Ackermann, “Genetic manipulation of glycogen allocation affects replicative lifespan in E coli,” PLoS Genetics, vol. 12, no. 4. Public Library of Science, 2016."},"type":"journal_article","department":[{"_id":"CaGu"}],"intvolume":" 12","isi":1,"publisher":"Public Library of Science","publist_id":"6077","ddc":["576","579"],"month":"04","quality_controlled":"1","status":"public","volume":12,"title":"Genetic manipulation of glycogen allocation affects replicative lifespan in E coli","_id":"1250","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"This manuscript is dedicated to the memory of Alex Böhm, who was a great friend and a passionate biologist. Alex passed away after the initial submission of this manuscript. We thank Vesna Olivera and Ursula Sauder from the Zentrum für Mikroskopie Uni Basel for excellent service, and Olin Silander, Nikki Freed, and Nela Nikolic for helpful discussions. This work was supported by the Swiss National Science Foundation grants to M. Ackermann and Urs Jenal (supporting AB).","external_id":{"isi":["000375231900025"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"issue":"4","scopus_import":"1","related_material":{"record":[{"status":"public","relation":"research_data","id":"9873"}]},"author":[{"first_name":"Alex","full_name":"Boehm, Alex","last_name":"Boehm"},{"full_name":"Arnoldini, Markus","first_name":"Markus","last_name":"Arnoldini"},{"last_name":"Bergmiller","orcid":"0000-0001-5396-4346","first_name":"Tobias","full_name":"Bergmiller, Tobias","id":"2C471CFA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Röösli, Thomas","first_name":"Thomas","last_name":"Röösli"},{"full_name":"Bigosch, Colette","first_name":"Colette","last_name":"Bigosch"},{"last_name":"Ackermann","first_name":"Martin","full_name":"Ackermann, Martin"}],"article_processing_charge":"No","year":"2016","date_updated":"2025-09-22T09:10:03Z","abstract":[{"text":"In bacteria, replicative aging manifests as a difference in growth or survival between the two cells emerging from division. One cell can be regarded as an aging mother with a decreased potential for future survival and division, the other as a rejuvenated daughter. Here, we aimed at investigating some of the processes involved in aging in the bacterium Escherichia coli, where the two types of cells can be distinguished by the age of their cell poles. We found that certain changes in the regulation of the carbohydrate metabolism can affect aging. A mutation in the carbon storage regulator gene, csrA, leads to a dramatically shorter replicative lifespan; csrA mutants stop dividing once their pole exceeds an age of about five divisions. These old-pole cells accumulate glycogen at their old cell poles; after their last division, they do not contain a chromosome, presumably because of spatial exclusion by the glycogen aggregates. The new-pole daughters produced by these aging mothers are born young; they only express the deleterious phenotype once their pole is old. These results demonstrate how manipulations of nutrient allocation can lead to the exclusion of the chromosome and limit replicative lifespan in E. coli, and illustrate how mutations can have phenotypic effects that are specific for cells with old poles. This raises the question how bacteria can avoid the accumulation of such mutations in their genomes over evolutionary times, and how they can achieve the long replicative lifespans that have recently been reported.","lang":"eng"}],"has_accepted_license":"1","oa_version":"Published Version"},{"citation":{"ieee":"J. Zhu et al., “TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics,” Plant Cell, vol. 28, no. 4. American Society of Plant Biologists, pp. 930–948, 2016.","chicago":"Zhu, Jinsheng, Aurélien Bailly, Marta Zwiewka, Valpuri Sovero, Martin Di Donato, Pei Ge, Jacqueline Oehri, et al. “TWISTED DWARF1 Mediates the Action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics.” Plant Cell. American Society of Plant Biologists, 2016. https://doi.org/10.1105/tpc.15.00726.","mla":"Zhu, Jinsheng, et al. “TWISTED DWARF1 Mediates the Action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics.” Plant Cell, vol. 28, no. 4, American Society of Plant Biologists, 2016, pp. 930–48, doi:10.1105/tpc.15.00726.","ista":"Zhu J, Bailly A, Zwiewka M, Sovero V, Di Donato M, Ge P, Oehri J, Aryal B, Hao P, Linnert M, Burgardt N, Lücke C, Weiwad M, Michel M, Weiergräber O, Pollmann S, Azzarello E, Mancuso S, Ferro N, Fukao Y, Hoffmann C, Wedlich Söldner R, Friml J, Thomas C, Geisler M. 2016. TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics. Plant Cell. 28(4), 930–948.","ama":"Zhu J, Bailly A, Zwiewka M, et al. TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics. Plant Cell. 2016;28(4):930-948. doi:10.1105/tpc.15.00726","short":"J. Zhu, A. Bailly, M. Zwiewka, V. Sovero, M. Di Donato, P. Ge, J. Oehri, B. Aryal, P. Hao, M. Linnert, N. Burgardt, C. Lücke, M. Weiwad, M. Michel, O. Weiergräber, S. Pollmann, E. Azzarello, S. Mancuso, N. Ferro, Y. Fukao, C. Hoffmann, R. Wedlich Söldner, J. Friml, C. Thomas, M. Geisler, Plant Cell 28 (2016) 930–948.","apa":"Zhu, J., Bailly, A., Zwiewka, M., Sovero, V., Di Donato, M., Ge, P., … Geisler, M. (2016). TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics. Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.15.00726"},"type":"journal_article","department":[{"_id":"JiFr"}],"intvolume":" 28","isi":1,"publisher":"American Society of Plant Biologists","date_created":"2018-12-11T11:50:57Z","language":[{"iso":"eng"}],"publication":"Plant Cell","oa":1,"date_published":"2016-04-01T00:00:00Z","doi":"10.1105/tpc.15.00726","day":"01","publication_status":"published","page":"930 - 948","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863381/","open_access":"1"}],"author":[{"last_name":"Zhu","full_name":"Zhu, Jinsheng","first_name":"Jinsheng"},{"last_name":"Bailly","full_name":"Bailly, Aurélien","first_name":"Aurélien"},{"full_name":"Zwiewka, Marta","first_name":"Marta","last_name":"Zwiewka"},{"last_name":"Sovero","full_name":"Sovero, Valpuri","first_name":"Valpuri"},{"full_name":"Di Donato, Martin","first_name":"Martin","last_name":"Di Donato"},{"last_name":"Ge","full_name":"Ge, Pei","first_name":"Pei"},{"full_name":"Oehri, Jacqueline","first_name":"Jacqueline","last_name":"Oehri"},{"last_name":"Aryal","full_name":"Aryal, Bibek","first_name":"Bibek"},{"first_name":"Pengchao","full_name":"Hao, Pengchao","last_name":"Hao"},{"full_name":"Linnert, Miriam","first_name":"Miriam","last_name":"Linnert"},{"first_name":"Noelia","full_name":"Burgardt, Noelia","last_name":"Burgardt"},{"full_name":"Lücke, Christian","first_name":"Christian","last_name":"Lücke"},{"last_name":"Weiwad","first_name":"Matthias","full_name":"Weiwad, Matthias"},{"last_name":"Michel","full_name":"Michel, Max","first_name":"Max"},{"last_name":"Weiergräber","first_name":"Oliver","full_name":"Weiergräber, Oliver"},{"last_name":"Pollmann","full_name":"Pollmann, Stephan","first_name":"Stephan"},{"first_name":"Elisa","full_name":"Azzarello, Elisa","last_name":"Azzarello"},{"last_name":"Mancuso","full_name":"Mancuso, Stefano","first_name":"Stefano"},{"last_name":"Ferro","first_name":"Noel","full_name":"Ferro, Noel"},{"first_name":"Yoichiro","full_name":"Fukao, Yoichiro","last_name":"Fukao"},{"full_name":"Hoffmann, Céline","first_name":"Céline","last_name":"Hoffmann"},{"full_name":"Wedlich Söldner, Roland","first_name":"Roland","last_name":"Wedlich Söldner"},{"orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","full_name":"Friml, Jirí"},{"last_name":"Thomas","full_name":"Thomas, Clément","first_name":"Clément"},{"last_name":"Geisler","full_name":"Geisler, Markus","first_name":"Markus"}],"article_processing_charge":"No","year":"2016","abstract":[{"lang":"eng","text":"Plant growth and architecture is regulated by the polar distribution of the hormone auxin. Polarity and flexibility of this process is provided by constant cycling of auxin transporter vesicles along actin filaments, coordinated by a positive auxinactin feedback loop. Both polar auxin transport and vesicle cycling are inhibited by synthetic auxin transport inhibitors, such as 1-Nnaphthylphthalamic acid (NPA), counteracting the effect of auxin; however, underlying targets and mechanisms are unclear. Using NMR, we map the NPA binding surface on the Arabidopsis thaliana ABCB chaperone TWISTED DWARF1 (TWD1).We identify ACTIN7 as a relevant, although likely indirect, TWD1 interactor, and show TWD1-dependent regulation of actin filament organization and dynamics and that TWD1 is required for NPA-mediated actin cytoskeleton remodeling. The TWD1-ACTIN7 axis controls plasma membrane presence of efflux transporters, and as a consequence act7 and twd1 share developmental and physiological phenotypes indicative of defects in auxin transport. These can be phenocopied by NPA treatment or by chemical actin (de)stabilization. We provide evidence that TWD1 determines downstreamlocations of auxin efflux transporters by adjusting actin filament debundling and dynamizing processes and mediating NPA action on the latter. This function appears to be evolutionary conserved since TWD1 expression in budding yeast alters actin polarization and cell polarity and provides NPA sensitivity."}],"date_updated":"2025-09-22T09:10:52Z","oa_version":"Submitted Version","external_id":{"isi":["000375416000012"]},"issue":"4","scopus_import":"1","status":"public","volume":28,"title":"TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics","_id":"1251","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":" This work was supported by grants from the European Social Fund (CZ.1.07/2.3.00/20.0043), the Czech Science Foundation GAČR (GA13-40637S) to J.F. and M.Z., the Ministry of Education, Youth, and Sports of the Czech Republic under the project CEITEC 2020 (LQ1601) to M.Z., the Ministry for Higher Education and Research of Luxembourg (REC-LOCM-20140703) to C.T., the Partial Funding Program for Short Stays Abroad of CONICET Argentina (to N.I.B.), Swiss National Funds, the Pool de Recherche of the University of Fribourg, and the Novartis Foundation (all to M.G.). ","publist_id":"6078","month":"04","quality_controlled":"1"},{"date_created":"2018-12-11T11:50:57Z","citation":{"short":"S. Harker, H. Kokubu, K. Mischaikow, P. Pilarczyk, Proceedings of the American Mathematical Society 144 (2016) 1787–1801.","ama":"Harker S, Kokubu H, Mischaikow K, Pilarczyk P. Inducing a map on homology from a correspondence. Proceedings of the American Mathematical Society. 2016;144(4):1787-1801. doi:10.1090/proc/12812","apa":"Harker, S., Kokubu, H., Mischaikow, K., & Pilarczyk, P. (2016). Inducing a map on homology from a correspondence. Proceedings of the American Mathematical Society. American Mathematical Society. https://doi.org/10.1090/proc/12812","mla":"Harker, Shaun, et al. “Inducing a Map on Homology from a Correspondence.” Proceedings of the American Mathematical Society, vol. 144, no. 4, American Mathematical Society, 2016, pp. 1787–801, doi:10.1090/proc/12812.","ista":"Harker S, Kokubu H, Mischaikow K, Pilarczyk P. 2016. Inducing a map on homology from a correspondence. Proceedings of the American Mathematical Society. 144(4), 1787–1801.","ieee":"S. Harker, H. Kokubu, K. Mischaikow, and P. Pilarczyk, “Inducing a map on homology from a correspondence,” Proceedings of the American Mathematical Society, vol. 144, no. 4. American Mathematical Society, pp. 1787–1801, 2016.","chicago":"Harker, Shaun, Hiroshi Kokubu, Konstantin Mischaikow, and Pawel Pilarczyk. “Inducing a Map on Homology from a Correspondence.” Proceedings of the American Mathematical Society. American Mathematical Society, 2016. https://doi.org/10.1090/proc/12812."},"department":[{"_id":"HeEd"}],"type":"journal_article","isi":1,"intvolume":" 144","publisher":"American Mathematical Society","day":"01","publication_status":"published","language":[{"iso":"eng"}],"publication":"Proceedings of the American Mathematical Society","project":[{"grant_number":"622033","_id":"255F06BE-B435-11E9-9278-68D0E5697425","name":"Persistent Homology - Images, Data and Maps","call_identifier":"FP7"}],"oa":1,"date_published":"2016-04-01T00:00:00Z","doi":"10.1090/proc/12812","external_id":{"arxiv":["1411.7563"],"isi":["000369298400038"]},"corr_author":"1","publication_identifier":{"issn":["1088-6826"]},"issue":"4","scopus_import":"1","page":"1787 - 1801","main_file_link":[{"url":"https://arxiv.org/abs/1411.7563","open_access":"1"}],"article_type":"original","year":"2016","article_processing_charge":"No","author":[{"last_name":"Harker","first_name":"Shaun","full_name":"Harker, Shaun"},{"full_name":"Kokubu, Hiroshi","first_name":"Hiroshi","last_name":"Kokubu"},{"full_name":"Mischaikow, Konstantin","first_name":"Konstantin","last_name":"Mischaikow"},{"id":"3768D56A-F248-11E8-B48F-1D18A9856A87","full_name":"Pilarczyk, Pawel","first_name":"Pawel","last_name":"Pilarczyk"}],"date_updated":"2025-09-22T09:09:31Z","abstract":[{"text":"We study the homomorphism induced in homology by a closed correspondence between topological spaces, using projections from the graph of the correspondence to its domain and codomain. We provide assumptions under which the homomorphism induced by an outer approximation of a continuous map coincides with the homomorphism induced in homology by the map. In contrast to more classical results we do not require that the projection to the domain have acyclic preimages. Moreover, we show that it is possible to retrieve correct homological information from a correspondence even if some data is missing or perturbed. Finally, we describe an application to combinatorial maps that are either outer approximations of continuous maps or reconstructions of such maps from a finite set of data points.","lang":"eng"}],"ec_funded":1,"oa_version":"Preprint","arxiv":1,"publist_id":"6075","month":"04","quality_controlled":"1","status":"public","volume":144,"title":"Inducing a map on homology from a correspondence","_id":"1252","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"The authors gratefully acknowledge the support of the Lorenz Center which\r\nprovided an opportunity for us to discuss in depth the work of this paper. Research leading to these results has received funding from Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE—Programa Operacional Factores de Competitividade (POFC) and from the Portuguese national funds through Funda¸c˜ao para a Ciˆencia e a Tecnologia (FCT) in the framework of the research\r\nproject FCOMP-01-0124-FEDER-010645 (ref. FCT PTDC/MAT/098871/2008),\r\nas well as from the People Programme (Marie Curie Actions) of the European\r\nUnion’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no. 622033 (supporting PP). The work of the first and third author has\r\nbeen partially supported by NSF grants NSF-DMS-0835621, 0915019, 1125174,\r\n1248071, and contracts from AFOSR and DARPA. The work of the second author\r\nwas supported by Grant-in-Aid for Scientific Research (No. 25287029), Ministry of\r\nEducation, Science, Technology, Culture and Sports, Japan."},{"date_created":"2018-12-11T11:50:58Z","pubrep_id":"981","citation":{"apa":"Tsai, L., & Siegert, S. (2016). How MicroRNAs Are involved in splitting the mind. JAMA Psychiatry. American Medical Association. https://doi.org/10.1001/jamapsychiatry.2015.3144","ama":"Tsai L, Siegert S. How MicroRNAs Are involved in splitting the mind. JAMA Psychiatry. 2016;73(4):409-410. doi:10.1001/jamapsychiatry.2015.3144","short":"L. Tsai, S. Siegert, JAMA Psychiatry 73 (2016) 409–410.","chicago":"Tsai, Lihuei, and Sandra Siegert. “How MicroRNAs Are Involved in Splitting the Mind.” JAMA Psychiatry. American Medical Association, 2016. https://doi.org/10.1001/jamapsychiatry.2015.3144.","ieee":"L. Tsai and S. Siegert, “How MicroRNAs Are involved in splitting the mind,” JAMA Psychiatry, vol. 73, no. 4. American Medical Association, pp. 409–410, 2016.","mla":"Tsai, Lihuei, and Sandra Siegert. “How MicroRNAs Are Involved in Splitting the Mind.” JAMA Psychiatry, vol. 73, no. 4, American Medical Association, 2016, pp. 409–10, doi:10.1001/jamapsychiatry.2015.3144.","ista":"Tsai L, Siegert S. 2016. How MicroRNAs Are involved in splitting the mind. JAMA Psychiatry. 73(4), 409–410."},"department":[{"_id":"SaSi"}],"type":"journal_article","publisher":"American Medical Association","intvolume":" 73","isi":1,"day":"01","publication_status":"published","file":[{"file_id":"5278","date_updated":"2020-07-14T12:44:41Z","creator":"system","access_level":"open_access","file_size":601679,"date_created":"2018-12-12T10:17:24Z","content_type":"application/pdf","relation":"main_file","checksum":"649aee381f30f7ef7e9efa912d41c2e3","file_name":"IST-2018-981-v1+1_YNP150011_annotatedproof_FINAL.pdf"}],"language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:44:41Z","publication":"JAMA Psychiatry","doi":"10.1001/jamapsychiatry.2015.3144","oa":1,"date_published":"2016-04-01T00:00:00Z","external_id":{"isi":["000373444700017"],"pmid":["26963490"]},"publication_identifier":{"issn":["2168-622X"]},"scopus_import":"1","issue":"4","page":"409 - 410","abstract":[{"text":"This article provides an introduction to the role of microRNAs in the nervous system and outlines their potential involvement in the pathophysiology of schizophrenia, which is hypothesized to arise owing to environmental factors and genetic predisposition.","lang":"eng"}],"date_updated":"2025-09-22T09:08:34Z","year":"2016","author":[{"first_name":"Lihuei","full_name":"Tsai, Lihuei","last_name":"Tsai"},{"orcid":"0000-0001-8635-0877","last_name":"Siegert","first_name":"Sandra","full_name":"Siegert, Sandra","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87"}],"article_processing_charge":"No","pmid":1,"has_accepted_license":"1","oa_version":"Submitted Version","publist_id":"6074","quality_controlled":"1","ddc":["576","610"],"month":"04","status":"public","title":"How MicroRNAs Are involved in splitting the mind","volume":73,"_id":"1253","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"doi":"10.1080/10586458.2015.1048011","oa":1,"date_published":"2016-04-02T00:00:00Z","project":[{"call_identifier":"FP7","_id":"255F06BE-B435-11E9-9278-68D0E5697425","grant_number":"622033","name":"Persistent Homology - Images, Data and Maps"}],"publication":"Experimental Mathematics","language":[{"iso":"eng"}],"publication_status":"published","day":"02","publisher":"Taylor and Francis","intvolume":" 25","isi":1,"department":[{"_id":"HeEd"}],"type":"journal_article","citation":{"mla":"Golmakani, Ali, et al. “Uniform Expansivity Outside a Critical Neighborhood in the Quadratic Family.” Experimental Mathematics, vol. 25, no. 2, Taylor and Francis, 2016, pp. 116–24, doi:10.1080/10586458.2015.1048011.","ista":"Golmakani A, Luzzatto S, Pilarczyk P. 2016. Uniform expansivity outside a critical neighborhood in the quadratic family. Experimental Mathematics. 25(2), 116–124.","chicago":"Golmakani, Ali, Stefano Luzzatto, and Pawel Pilarczyk. “Uniform Expansivity Outside a Critical Neighborhood in the Quadratic Family.” Experimental Mathematics. Taylor and Francis, 2016. https://doi.org/10.1080/10586458.2015.1048011.","ieee":"A. Golmakani, S. Luzzatto, and P. Pilarczyk, “Uniform expansivity outside a critical neighborhood in the quadratic family,” Experimental Mathematics, vol. 25, no. 2. Taylor and Francis, pp. 116–124, 2016.","apa":"Golmakani, A., Luzzatto, S., & Pilarczyk, P. (2016). Uniform expansivity outside a critical neighborhood in the quadratic family. Experimental Mathematics. Taylor and Francis. https://doi.org/10.1080/10586458.2015.1048011","short":"A. Golmakani, S. Luzzatto, P. Pilarczyk, Experimental Mathematics 25 (2016) 116–124.","ama":"Golmakani A, Luzzatto S, Pilarczyk P. Uniform expansivity outside a critical neighborhood in the quadratic family. Experimental Mathematics. 2016;25(2):116-124. doi:10.1080/10586458.2015.1048011"},"date_created":"2018-12-11T11:50:58Z","acknowledgement":"AG and PP were partially supported by Abdus Salam International Centre for Theoretical Physics (ICTP). Additionally, AG was supported by BREUDS, and research conducted by PP has received funding from Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE—Programa Operacional Factores de Competitividade (POFC) and from the Portuguese national funds through Fundação para a Ciência e a Tecnologia (FCT) in the framework of the research project FCOMP-01-0124-FEDER-010645 (ref. FCT PTDC/MAT/098871/2008); and from the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no. 622033. The authors gratefully acknowledge the Department of\r\nMathematics of Kyoto University for providing access\r\nto their server for conducting computations for this\r\nproject.","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","_id":"1254","title":"Uniform expansivity outside a critical neighborhood in the quadratic family","volume":25,"status":"public","quality_controlled":"1","month":"04","publist_id":"6071","arxiv":1,"oa_version":"Preprint","ec_funded":1,"date_updated":"2025-09-22T09:07:52Z","abstract":[{"text":"We use rigorous numerical techniques to compute a lower bound for the exponent of expansivity outside a neighborhood of the critical point for thousands of intervals of parameter values in the quadratic family. We first compute a radius of the critical neighborhood outside which the map is uniformly expanding. This radius is taken as small as possible, yet large enough for our numerical procedure to succeed in proving that the expansivity exponent outside this neighborhood is positive. Then, for each of the intervals, we compute a lower bound for this expansivity exponent, valid for all the parameters in that interval. We illustrate and study the distribution of the radii and the expansivity exponents. The results of our computations are mathematically rigorous. The source code of the software and the results of the computations are made publicly available at http://www.pawelpilarczyk.com/quadratic/.","lang":"eng"}],"author":[{"full_name":"Golmakani, Ali","first_name":"Ali","last_name":"Golmakani"},{"first_name":"Stefano","full_name":"Luzzatto, Stefano","last_name":"Luzzatto"},{"first_name":"Pawel","full_name":"Pilarczyk, Pawel","id":"3768D56A-F248-11E8-B48F-1D18A9856A87","last_name":"Pilarczyk"}],"article_processing_charge":"No","year":"2016","main_file_link":[{"url":"https://arxiv.org/abs/1504.00116","open_access":"1"}],"page":"116 - 124","issue":"2","scopus_import":"1","corr_author":"1","external_id":{"arxiv":["1504.00116"],"isi":["000372490500002"]}},{"day":"01","publication_status":"published","article_number":"160138","file":[{"file_id":"5049","creator":"system","date_updated":"2020-07-14T12:44:41Z","access_level":"open_access","file_size":627377,"date_created":"2018-12-12T10:14:01Z","content_type":"application/pdf","checksum":"c3cd84666c8dc0ce6a784f1c82c1cf68","relation":"main_file","file_name":"IST-2016-704-v1+1_160138.full.pdf"}],"language":[{"iso":"eng"}],"publication":"Royal Society Open Science","file_date_updated":"2020-07-14T12:44:41Z","doi":"10.1098/rsos.160138","oa":1,"date_published":"2016-04-01T00:00:00Z","date_created":"2018-12-11T11:50:58Z","pubrep_id":"704","citation":{"chicago":"Peuß, Robert, Kristina Wensing, Luisa Woestmann, Hendrik Eggert, Barbara Milutinovic, Marlene Sroka, Jörn Scharsack, Joachim Kurtz, and Sophie Armitage. “Down Syndrome Cell Adhesion Molecule 1: Testing for a Role in Insect Immunity, Behaviour and Reproduction.” Royal Society Open Science. Royal Society, The, 2016. https://doi.org/10.1098/rsos.160138.","ieee":"R. Peuß et al., “Down syndrome cell adhesion molecule 1: Testing for a role in insect immunity, behaviour and reproduction,” Royal Society Open Science, vol. 3, no. 4. Royal Society, The, 2016.","ista":"Peuß R, Wensing K, Woestmann L, Eggert H, Milutinovic B, Sroka M, Scharsack J, Kurtz J, Armitage S. 2016. Down syndrome cell adhesion molecule 1: Testing for a role in insect immunity, behaviour and reproduction. Royal Society Open Science. 3(4), 160138.","mla":"Peuß, Robert, et al. “Down Syndrome Cell Adhesion Molecule 1: Testing for a Role in Insect Immunity, Behaviour and Reproduction.” Royal Society Open Science, vol. 3, no. 4, 160138, Royal Society, The, 2016, doi:10.1098/rsos.160138.","apa":"Peuß, R., Wensing, K., Woestmann, L., Eggert, H., Milutinovic, B., Sroka, M., … Armitage, S. (2016). Down syndrome cell adhesion molecule 1: Testing for a role in insect immunity, behaviour and reproduction. Royal Society Open Science. Royal Society, The. https://doi.org/10.1098/rsos.160138","ama":"Peuß R, Wensing K, Woestmann L, et al. Down syndrome cell adhesion molecule 1: Testing for a role in insect immunity, behaviour and reproduction. Royal Society Open Science. 2016;3(4). doi:10.1098/rsos.160138","short":"R. Peuß, K. Wensing, L. Woestmann, H. Eggert, B. Milutinovic, M. Sroka, J. Scharsack, J. Kurtz, S. Armitage, Royal Society Open Science 3 (2016)."},"department":[{"_id":"SyCr"}],"type":"journal_article","publisher":"Royal Society, The","isi":1,"intvolume":" 3","publist_id":"6070","quality_controlled":"1","month":"04","ddc":["576","592"],"status":"public","title":"Down syndrome cell adhesion molecule 1: Testing for a role in insect immunity, behaviour and reproduction","volume":3,"_id":"1255","acknowledgement":"We thank Dietmar Schmucker for reading a draft of this manuscript and thank him and his group for\r\nhelpful discussions. We thank Barbara Hasert, Kevin Ferro and Manuel F. Talarico for technical support and helpful\r\ndiscussions. We also thank two anonymous reviewers for their comments. This study was supported by grants from the Volkswagen Stiftung (1/83 516 and AZ 86020: both to S.A.O.A.) and from the DFG priority programme 1399 ‘Host parasite coevolution’ (KU 1929/4-2 to R.P. and J.K.).","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","external_id":{"isi":["000377969500026"]},"issue":"4","scopus_import":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"abstract":[{"text":"Down syndrome cell adhesion molecule 1 (Dscam1) has widereaching and vital neuronal functions although the role it plays in insect and crustacean immunity is less well understood. In this study, we combine different approaches to understand the roles that Dscam1 plays in fitness-related contexts in two model insect species. Contrary to our expectations, we found no short-term modulation of Dscam1 gene expression after haemocoelic or oral bacterial exposure in Tribolium castaneum, or after haemocoelic bacterial exposure in Drosophila melanogaster. Furthermore, RNAi-mediated Dscam1 knockdown and subsequent bacterial exposure did not reduce T. castaneum survival. However, Dscam1 knockdown in larvae resulted in adult locomotion defects, as well as dramatically reduced fecundity in males and females. We suggest that Dscam1 does not always play a straightforward role in immunity, but strongly influences behaviour and fecundity. This study takes a step towards understanding more about the role of this intriguing gene from different phenotypic perspectives.","lang":"eng"}],"date_updated":"2025-09-22T09:06:29Z","author":[{"full_name":"Peuß, Robert","first_name":"Robert","last_name":"Peuß"},{"full_name":"Wensing, Kristina","first_name":"Kristina","last_name":"Wensing"},{"first_name":"Luisa","full_name":"Woestmann, Luisa","last_name":"Woestmann"},{"full_name":"Eggert, Hendrik","first_name":"Hendrik","last_name":"Eggert"},{"first_name":"Barbara","full_name":"Milutinovic, Barbara","id":"2CDC32B8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8214-4758","last_name":"Milutinovic"},{"full_name":"Sroka, Marlene","first_name":"Marlene","last_name":"Sroka"},{"first_name":"Jörn","full_name":"Scharsack, Jörn","last_name":"Scharsack"},{"last_name":"Kurtz","first_name":"Joachim","full_name":"Kurtz, Joachim"},{"first_name":"Sophie","full_name":"Armitage, Sophie","last_name":"Armitage"}],"article_processing_charge":"No","year":"2016","has_accepted_license":"1","oa_version":"Published Version"},{"citation":{"ieee":"Y. Jiang et al., “From stateflow simulation to verified implementation: A verification approach and a real-time train controller design,” presented at the RTAS: Real-time and Embedded Technology and Applications Symposium, Vienna, Austria, 2016.","chicago":"Jiang, Yu, Yixiao Yang, Han Liu, Hui Kong, Ming Gu, Jiaguang Sun, and Lui Sha. “From Stateflow Simulation to Verified Implementation: A Verification Approach and a Real-Time Train Controller Design.” IEEE, 2016. https://doi.org/10.1109/RTAS.2016.7461337.","mla":"Jiang, Yu, et al. From Stateflow Simulation to Verified Implementation: A Verification Approach and a Real-Time Train Controller Design. 7461337, IEEE, 2016, doi:10.1109/RTAS.2016.7461337.","ista":"Jiang Y, Yang Y, Liu H, Kong H, Gu M, Sun J, Sha L. 2016. From stateflow simulation to verified implementation: A verification approach and a real-time train controller design. RTAS: Real-time and Embedded Technology and Applications Symposium, 7461337.","ama":"Jiang Y, Yang Y, Liu H, et al. From stateflow simulation to verified implementation: A verification approach and a real-time train controller design. In: IEEE; 2016. doi:10.1109/RTAS.2016.7461337","short":"Y. Jiang, Y. Yang, H. Liu, H. Kong, M. Gu, J. Sun, L. Sha, in:, IEEE, 2016.","apa":"Jiang, Y., Yang, Y., Liu, H., Kong, H., Gu, M., Sun, J., & Sha, L. (2016). From stateflow simulation to verified implementation: A verification approach and a real-time train controller design. Presented at the RTAS: Real-time and Embedded Technology and Applications Symposium, Vienna, Austria: IEEE. https://doi.org/10.1109/RTAS.2016.7461337"},"department":[{"_id":"ToHe"}],"type":"conference","publisher":"IEEE","date_created":"2018-12-11T11:50:58Z","pubrep_id":"780","language":[{"iso":"eng"}],"file":[{"file_size":1293599,"date_created":"2018-12-12T10:12:31Z","content_type":"application/pdf","relation":"main_file","checksum":"42f0462911cc9957f2356b12fb33b4b6","file_name":"IST-2017-780-v1+1_RTAS-42-Camera-Ready.pdf","file_id":"4949","creator":"system","date_updated":"2020-07-14T12:44:41Z","access_level":"open_access"}],"file_date_updated":"2020-07-14T12:44:41Z","date_published":"2016-04-27T00:00:00Z","conference":{"name":"RTAS: Real-time and Embedded Technology and Applications Symposium","location":"Vienna, Austria","end_date":"2016-04-14","start_date":"2016-04-11"},"oa":1,"doi":"10.1109/RTAS.2016.7461337","day":"27","publication_status":"published","article_number":"7461337","year":"2016","author":[{"first_name":"Yu","full_name":"Jiang, Yu","last_name":"Jiang"},{"full_name":"Yang, Yixiao","first_name":"Yixiao","last_name":"Yang"},{"full_name":"Liu, Han","first_name":"Han","last_name":"Liu"},{"last_name":"Kong","orcid":"0000-0002-3066-6941","id":"3BDE25AA-F248-11E8-B48F-1D18A9856A87","first_name":"Hui","full_name":"Kong, Hui"},{"last_name":"Gu","full_name":"Gu, Ming","first_name":"Ming"},{"first_name":"Jiaguang","full_name":"Sun, Jiaguang","last_name":"Sun"},{"last_name":"Sha","first_name":"Lui","full_name":"Sha, Lui"}],"abstract":[{"lang":"eng","text":"Simulink is widely used for model driven development (MDD) of industrial software systems. Typically, the Simulink based development is initiated from Stateflow modeling, followed by simulation, validation and code generation mapped to physical execution platforms. However, recent industrial trends have raised the demands of rigorous verification on safety-critical applications, which is unfortunately challenging for Simulink. In this paper, we present an approach to bridge the Stateflow based model driven development and a well- defined rigorous verification. First, we develop a self- contained toolkit to translate Stateflow model into timed automata, where major advanced modeling features in Stateflow are supported. Taking advantage of the strong verification capability of Uppaal, we can not only find bugs in Stateflow models which are missed by Simulink Design Verifier, but also check more important temporal properties. Next, we customize a runtime verifier for the generated nonintrusive VHDL and C code of Stateflow model for monitoring. The major strength of the customization is the flexibility to collect and analyze runtime properties with a pure software monitor, which opens more opportunities for engineers to achieve high reliability of the target system compared with the traditional act that only relies on Simulink Polyspace. We incorporate these two parts into original Stateflow based MDD seamlessly. In this way, safety-critical properties are both verified at the model level, and at the consistent system implementation level with physical execution environment in consideration. We apply our approach on a train controller design, and the verified implementation is tested and deployed on a real hardware platform."}],"date_updated":"2021-01-12T06:49:26Z","has_accepted_license":"1","oa_version":"Submitted Version","scopus_import":1,"status":"public","title":"From stateflow simulation to verified implementation: A verification approach and a real-time train controller design","_id":"1256","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","acknowledgement":"This work is supported in part by NSF CNS 13-30077, NSF CNS 13-29886, NSF CNS 15-45002, NSFC 61303014, NSFC 61202010, and NSFC 91218302.","publist_id":"6069","ddc":["005"],"month":"04","quality_controlled":"1"},{"citation":{"apa":"Sadel, C., & Virág, B. (2016). A central limit theorem for products of random matrices and GOE statistics for the Anderson model on long boxes. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-016-2600-4","ama":"Sadel C, Virág B. A central limit theorem for products of random matrices and GOE statistics for the Anderson model on long boxes. Communications in Mathematical Physics. 2016;343(3):881-919. doi:10.1007/s00220-016-2600-4","short":"C. Sadel, B. Virág, Communications in Mathematical Physics 343 (2016) 881–919.","chicago":"Sadel, Christian, and Bálint Virág. “A Central Limit Theorem for Products of Random Matrices and GOE Statistics for the Anderson Model on Long Boxes.” Communications in Mathematical Physics. Springer, 2016. https://doi.org/10.1007/s00220-016-2600-4.","ieee":"C. Sadel and B. Virág, “A central limit theorem for products of random matrices and GOE statistics for the Anderson model on long boxes,” Communications in Mathematical Physics, vol. 343, no. 3. Springer, pp. 881–919, 2016.","mla":"Sadel, Christian, and Bálint Virág. “A Central Limit Theorem for Products of Random Matrices and GOE Statistics for the Anderson Model on Long Boxes.” Communications in Mathematical Physics, vol. 343, no. 3, Springer, 2016, pp. 881–919, doi:10.1007/s00220-016-2600-4.","ista":"Sadel C, Virág B. 2016. A central limit theorem for products of random matrices and GOE statistics for the Anderson model on long boxes. Communications in Mathematical Physics. 343(3), 881–919."},"publisher":"Springer","isi":1,"intvolume":" 343","department":[{"_id":"LaEr"}],"type":"journal_article","pubrep_id":"703","date_created":"2018-12-11T11:50:59Z","project":[{"call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"publication":"Communications in Mathematical Physics","file_date_updated":"2020-07-14T12:44:42Z","file":[{"access_level":"open_access","date_updated":"2020-07-14T12:44:42Z","creator":"system","file_id":"5119","file_name":"IST-2016-703-v1+1_s00220-016-2600-4.pdf","relation":"main_file","checksum":"4fb2411d9c2f56676123165aad46c828","date_created":"2018-12-12T10:15:02Z","file_size":800792,"content_type":"application/pdf"}],"language":[{"iso":"eng"}],"doi":"10.1007/s00220-016-2600-4","date_published":"2016-05-01T00:00:00Z","oa":1,"day":"01","publication_status":"published","page":"881 - 919","oa_version":"Published Version","has_accepted_license":"1","date_updated":"2025-09-22T09:02:32Z","abstract":[{"text":"We consider products of random matrices that are small, independent identically distributed perturbations of a fixed matrix (Formula presented.). Focusing on the eigenvalues of (Formula presented.) of a particular size we obtain a limit to a SDE in a critical scaling. Previous results required (Formula presented.) to be a (conjugated) unitary matrix so it could not have eigenvalues of different modulus. From the result we can also obtain a limit SDE for the Markov process given by the action of the random products on the flag manifold. Applying the result to random Schrödinger operators we can improve some results by Valko and Virag showing GOE statistics for the rescaled eigenvalue process of a sequence of Anderson models on long boxes. In particular, we solve a problem posed in their work.","lang":"eng"}],"ec_funded":1,"year":"2016","article_processing_charge":"Yes (via OA deal)","author":[{"id":"4760E9F8-F248-11E8-B48F-1D18A9856A87","first_name":"Christian","full_name":"Sadel, Christian","orcid":"0000-0001-8255-3968","last_name":"Sadel"},{"first_name":"Bálint","full_name":"Virág, Bálint","last_name":"Virág"}],"external_id":{"isi":["000374659800005"]},"issue":"3","scopus_import":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"corr_author":"1","title":"A central limit theorem for products of random matrices and GOE statistics for the Anderson model on long boxes","volume":343,"status":"public","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). The work of C. Sadel was supported by NSERC Discovery Grant 92997-2010 RGPIN and by the People Programme (Marie Curie Actions) of the EU 7th Framework Programme FP7/2007-2013, REA Grant 291734.","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","_id":"1257","quality_controlled":"1","month":"05","ddc":["510","539"],"publist_id":"6067"},{"publication_status":"published","day":"03","doi":"10.1242/dev.130211","date_published":"2016-05-03T00:00:00Z","publication":"Development","language":[{"iso":"eng"}],"date_created":"2018-12-11T11:50:59Z","publisher":"Company of Biologists","isi":1,"intvolume":" 143","department":[{"_id":"EvBe"}],"type":"journal_article","citation":{"chicago":"Gallemi, Marçal, Anahit Galstyan, Sandi Paulišić, Christiane Then, Almudena Ferrández Ayela, Laura Lorenzo Orts, Irma Roig Villanova, et al. “DRACULA2 Is a Dynamic Nucleoporin with a Role in Regulating the Shade Avoidance Syndrome in Arabidopsis.” Development. Company of Biologists, 2016. https://doi.org/10.1242/dev.130211.","ieee":"M. Gallemi et al., “DRACULA2 is a dynamic nucleoporin with a role in regulating the shade avoidance syndrome in Arabidopsis,” Development, vol. 143, no. 9. Company of Biologists, pp. 1623–1631, 2016.","mla":"Gallemi, Marçal, et al. “DRACULA2 Is a Dynamic Nucleoporin with a Role in Regulating the Shade Avoidance Syndrome in Arabidopsis.” Development, vol. 143, no. 9, Company of Biologists, 2016, pp. 1623–31, doi:10.1242/dev.130211.","ista":"Gallemi M, Galstyan A, Paulišić S, Then C, Ferrández Ayela A, Lorenzo Orts L, Roig Villanova I, Wang X, Micol J, Ponce M, Devlin P, Martínez García J. 2016. DRACULA2 is a dynamic nucleoporin with a role in regulating the shade avoidance syndrome in Arabidopsis. Development. 143(9), 1623–1631.","apa":"Gallemi, M., Galstyan, A., Paulišić, S., Then, C., Ferrández Ayela, A., Lorenzo Orts, L., … Martínez García, J. (2016). DRACULA2 is a dynamic nucleoporin with a role in regulating the shade avoidance syndrome in Arabidopsis. Development. Company of Biologists. https://doi.org/10.1242/dev.130211","ama":"Gallemi M, Galstyan A, Paulišić S, et al. DRACULA2 is a dynamic nucleoporin with a role in regulating the shade avoidance syndrome in Arabidopsis. Development. 2016;143(9):1623-1631. doi:10.1242/dev.130211","short":"M. Gallemi, A. Galstyan, S. Paulišić, C. Then, A. Ferrández Ayela, L. Lorenzo Orts, I. Roig Villanova, X. Wang, J. Micol, M. Ponce, P. Devlin, J. Martínez García, Development 143 (2016) 1623–1631."},"quality_controlled":"1","month":"05","publist_id":"6068","acknowledgement":"M.G. received an FPI fellowship from the Spanish Ministerio de Economía y Competitividad (MINECO). A.G. and A.F.-A. received FPU fellowships from the Spanish Ministerio de Educación. S.P. received an FI fellowship from the Agència de Gestió D'ajuts Universitaris i de Recerca (AGAUR - Generalitat de Catalunya). C.T. received a Marie Curie IEF postdoctoral contract funded by the European Commission. I.R.-V. received initially an FPI fellowship from the Spanish MINECO and later a Beatriu de Pinós contract from AGAUR. Our research is supported by grants from the Spanish MINECO-FEDER [BIO2008-00169, BIO2011-23489 and BIO2014-59895-P] and Generalitat de Catalunya [2011-SGR447 and Xarba] to J.F.M.-G., and Generalitat Valenciana [PROMETEO/2009/112, PROMETEOII/2014/006] to M.R.P. and J.L.M. We acknowledge the support of the Spanish MINECO for the ‘Centro de Excelencia Severo Ochoa 2016-2019’ [award SEV-2015-0533]. We thank the CRAG greenhouse service for plant care; Chus Burillo for technical help; Sergi Portolés and Carles Rentero for assistance with mutagenesis; Mark Estelle (UCSD, USA) for providing sar1-4, sar3-1 and sar3-3 seeds; Juanjo López-Moya (CRAG, Barcelona; 35S:HcPro plasmid) and Dolors Ludevid (CRAG; C307 plasmid) for providing DNA plasmids; and Manuel Rodríguez-Concepción (CRAG) and Miguel Blázquez (IBMCP, Valencia, Spain) for comments on the manuscript.","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","_id":"1258","title":"DRACULA2 is a dynamic nucleoporin with a role in regulating the shade avoidance syndrome in Arabidopsis","volume":143,"status":"public","scopus_import":"1","issue":"9","external_id":{"isi":["000389588100018"]},"oa_version":"None","date_updated":"2025-09-22T09:05:00Z","abstract":[{"text":"When plants grow in close proximity basic resources such as light can become limiting. Under such conditions plants respond to anticipate and/or adapt to the light shortage, a process known as the shade avoidance syndrome (SAS). Following genetic screening using a shade-responsive luciferase reporter line (PHYB:LUC), we identified DRACULA2 (DRA2), which encodes an Arabidopsis homolog of mammalian nucleoporin 98, a component of the nuclear pore complex (NPC). DRA2, together with other nucleoporins, participates positively in the control of the hypocotyl elongation response to plant proximity, a role that can be considered dependent on the nucleocytoplasmic transport of macromolecules (i.e. is transport dependent). In addition, our results reveal a specific role for DRA2 in controlling shade-induced gene expression. We suggest that this novel regulatory role of DRA2 is transport independent and that it might rely on its dynamic localization within and outside of the NPC. These results provide mechanistic insights in to how SAS responses are rapidly established by light conditions. They also indicate that nucleoporins have an active role in plant signaling.","lang":"eng"}],"author":[{"id":"460C6802-F248-11E8-B48F-1D18A9856A87","full_name":"Gallemi Rovira, Marcal","first_name":"Marcal","orcid":"0000-0003-4675-6893","last_name":"Gallemi Rovira"},{"full_name":"Galstyan, Anahit","first_name":"Anahit","last_name":"Galstyan"},{"full_name":"Paulišić, Sandi","first_name":"Sandi","last_name":"Paulišić"},{"first_name":"Christiane","full_name":"Then, Christiane","last_name":"Then"},{"last_name":"Ferrández Ayela","first_name":"Almudena","full_name":"Ferrández Ayela, Almudena"},{"last_name":"Lorenzo Orts","full_name":"Lorenzo Orts, Laura","first_name":"Laura"},{"last_name":"Roig Villanova","first_name":"Irma","full_name":"Roig Villanova, Irma"},{"last_name":"Wang","first_name":"Xuewen","full_name":"Wang, Xuewen"},{"last_name":"Micol","first_name":"José","full_name":"Micol, José"},{"last_name":"Ponce","first_name":"Maria","full_name":"Ponce, Maria"},{"full_name":"Devlin, Paul","first_name":"Paul","last_name":"Devlin"},{"full_name":"Martínez García, Jaime","first_name":"Jaime","last_name":"Martínez García"}],"article_processing_charge":"No","year":"2016","page":"1623 - 1631"},{"oa_version":"Published Version","has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","year":"2016","author":[{"first_name":"Gerhard","full_name":"Bräunlich, Gerhard","last_name":"Bräunlich"},{"last_name":"Hainzl","full_name":"Hainzl, Christian","first_name":"Christian"},{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521","last_name":"Seiringer"}],"abstract":[{"lang":"eng","text":"We consider the Bogolubov–Hartree–Fock functional for a fermionic many-body system with two-body interactions. For suitable interaction potentials that have a strong enough attractive tail in order to allow for two-body bound states, but are otherwise sufficiently repulsive to guarantee stability of the system, we show that in the low-density limit the ground state of this model consists of a Bose–Einstein condensate of fermion pairs. The latter can be described by means of the Gross–Pitaevskii energy functional."}],"date_updated":"2025-09-22T09:02:01Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"scopus_import":"1","issue":"2","corr_author":"1","external_id":{"isi":["000377379300001"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"Partial financial support from the DFG grant GRK 1838, as well as the Austrian Science Fund (FWF), project Nr. P 27533-N27 (R.S.), is gratefully acknowledged.","_id":"1259","volume":19,"title":"Bogolubov–Hartree–Fock theory for strongly interacting fermions in the low density limit","status":"public","ddc":["510","539"],"month":"06","quality_controlled":"1","publist_id":"6066","isi":1,"intvolume":" 19","publisher":"Springer","type":"journal_article","department":[{"_id":"RoSe"}],"citation":{"apa":"Bräunlich, G., Hainzl, C., & Seiringer, R. (2016). Bogolubov–Hartree–Fock theory for strongly interacting fermions in the low density limit. Mathematical Physics, Analysis and Geometry. Springer. https://doi.org/10.1007/s11040-016-9209-x","short":"G. Bräunlich, C. Hainzl, R. Seiringer, Mathematical Physics, Analysis and Geometry 19 (2016).","ama":"Bräunlich G, Hainzl C, Seiringer R. Bogolubov–Hartree–Fock theory for strongly interacting fermions in the low density limit. Mathematical Physics, Analysis and Geometry. 2016;19(2). doi:10.1007/s11040-016-9209-x","ista":"Bräunlich G, Hainzl C, Seiringer R. 2016. Bogolubov–Hartree–Fock theory for strongly interacting fermions in the low density limit. Mathematical Physics, Analysis and Geometry. 19(2), 13.","mla":"Bräunlich, Gerhard, et al. “Bogolubov–Hartree–Fock Theory for Strongly Interacting Fermions in the Low Density Limit.” Mathematical Physics, Analysis and Geometry, vol. 19, no. 2, 13, Springer, 2016, doi:10.1007/s11040-016-9209-x.","ieee":"G. Bräunlich, C. Hainzl, and R. Seiringer, “Bogolubov–Hartree–Fock theory for strongly interacting fermions in the low density limit,” Mathematical Physics, Analysis and Geometry, vol. 19, no. 2. Springer, 2016.","chicago":"Bräunlich, Gerhard, Christian Hainzl, and Robert Seiringer. “Bogolubov–Hartree–Fock Theory for Strongly Interacting Fermions in the Low Density Limit.” Mathematical Physics, Analysis and Geometry. Springer, 2016. https://doi.org/10.1007/s11040-016-9209-x."},"pubrep_id":"702","date_created":"2018-12-11T11:50:59Z","oa":1,"date_published":"2016-06-01T00:00:00Z","doi":"10.1007/s11040-016-9209-x","file_date_updated":"2020-07-14T12:44:42Z","publication":"Mathematical Physics, Analysis and Geometry","project":[{"grant_number":"P27533_N27","_id":"25C878CE-B435-11E9-9278-68D0E5697425","name":"Structure of the Excitation Spectrum for Many-Body Quantum Systems","call_identifier":"FWF"}],"language":[{"iso":"eng"}],"file":[{"checksum":"9954f685cc25c58d7f1712c67b47ad8d","relation":"main_file","file_name":"IST-2016-702-v1+1_s11040-016-9209-x.pdf","content_type":"application/pdf","date_created":"2018-12-12T10:09:13Z","file_size":506242,"creator":"system","date_updated":"2020-07-14T12:44:42Z","access_level":"open_access","file_id":"4736"}],"article_number":"13","publication_status":"published","day":"01"},{"title":"The dual of the space of interactions in neural network models","volume":27,"status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","_id":"1260","quality_controlled":"1","month":"06","publist_id":"6065","article_type":"original","main_file_link":[{"url":"https://arxiv.org/abs/1505.02963","open_access":"1"}],"oa_version":"Preprint","arxiv":1,"abstract":[{"lang":"eng","text":"In this work, the Gardner problem of inferring interactions and fields for an Ising neural network from given patterns under a local stability hypothesis is addressed under a dual perspective. By means of duality arguments, an integer linear system is defined whose solution space is the dual of the Gardner space and whose solutions represent mutually unstable patterns. We propose and discuss Monte Carlo methods in order to find and remove unstable patterns and uniformly sample the space of interactions thereafter. We illustrate the problem on a set of real data and perform ensemble calculation that shows how the emergence of phase dominated by unstable patterns can be triggered in a nonlinear discontinuous way."}],"date_updated":"2025-09-22T09:01:25Z","author":[{"full_name":"De Martino, Daniele","first_name":"Daniele","id":"3FF5848A-F248-11E8-B48F-1D18A9856A87","last_name":"De Martino","orcid":"0000-0002-5214-4706"}],"article_processing_charge":"No","year":"2016","external_id":{"isi":["000377674800010"],"arxiv":["1505.02963"]},"scopus_import":"1","issue":"6","corr_author":"1","publication":"International Journal of Modern Physics C","language":[{"iso":"eng"}],"doi":"10.1142/S0129183116500674","date_published":"2016-06-01T00:00:00Z","oa":1,"day":"01","article_number":"1650067","publication_status":"published","citation":{"mla":"De Martino, Daniele. “The Dual of the Space of Interactions in Neural Network Models.” International Journal of Modern Physics C, vol. 27, no. 6, 1650067, World Scientific Publishing, 2016, doi:10.1142/S0129183116500674.","ista":"De Martino D. 2016. The dual of the space of interactions in neural network models. International Journal of Modern Physics C. 27(6), 1650067.","ieee":"D. De Martino, “The dual of the space of interactions in neural network models,” International Journal of Modern Physics C, vol. 27, no. 6. World Scientific Publishing, 2016.","chicago":"De Martino, Daniele. “The Dual of the Space of Interactions in Neural Network Models.” International Journal of Modern Physics C. World Scientific Publishing, 2016. https://doi.org/10.1142/S0129183116500674.","apa":"De Martino, D. (2016). The dual of the space of interactions in neural network models. International Journal of Modern Physics C. World Scientific Publishing. https://doi.org/10.1142/S0129183116500674","short":"D. De Martino, International Journal of Modern Physics C 27 (2016).","ama":"De Martino D. The dual of the space of interactions in neural network models. International Journal of Modern Physics C. 2016;27(6). doi:10.1142/S0129183116500674"},"publisher":"World Scientific Publishing","intvolume":" 27","isi":1,"department":[{"_id":"GaTk"}],"type":"journal_article","date_created":"2018-12-11T11:51:00Z"},{"day":"10","publication_status":"published","language":[{"iso":"eng"}],"publication":"Nonlinearity","doi":"10.1088/0951-7715/29/7/1992","date_published":"2016-06-10T00:00:00Z","oa":1,"date_created":"2018-12-11T11:51:00Z","citation":{"apa":"Maas, J., & Matthes, D. (2016). Long-time behavior of a finite volume discretization for a fourth order diffusion equation. Nonlinearity. IOP Publishing. https://doi.org/10.1088/0951-7715/29/7/1992","short":"J. Maas, D. Matthes, Nonlinearity 29 (2016) 1992–2023.","ama":"Maas J, Matthes D. Long-time behavior of a finite volume discretization for a fourth order diffusion equation. Nonlinearity. 2016;29(7):1992-2023. doi:10.1088/0951-7715/29/7/1992","ista":"Maas J, Matthes D. 2016. Long-time behavior of a finite volume discretization for a fourth order diffusion equation. Nonlinearity. 29(7), 1992–2023.","mla":"Maas, Jan, and Daniel Matthes. “Long-Time Behavior of a Finite Volume Discretization for a Fourth Order Diffusion Equation.” Nonlinearity, vol. 29, no. 7, IOP Publishing, 2016, pp. 1992–2023, doi:10.1088/0951-7715/29/7/1992.","chicago":"Maas, Jan, and Daniel Matthes. “Long-Time Behavior of a Finite Volume Discretization for a Fourth Order Diffusion Equation.” Nonlinearity. IOP Publishing, 2016. https://doi.org/10.1088/0951-7715/29/7/1992.","ieee":"J. Maas and D. Matthes, “Long-time behavior of a finite volume discretization for a fourth order diffusion equation,” Nonlinearity, vol. 29, no. 7. IOP Publishing, pp. 1992–2023, 2016."},"type":"journal_article","department":[{"_id":"JaMa"}],"publisher":"IOP Publishing","isi":1,"intvolume":" 29","publist_id":"6062","quality_controlled":"1","month":"06","status":"public","title":"Long-time behavior of a finite volume discretization for a fourth order diffusion equation","volume":29,"_id":"1261","acknowledgement":"This research was supported by the DFG Collaborative Research Centers TRR 109, ‘ Discretization in Geometry and Dynamics ’ and 1060 ‘ The Mathematics of Emergent Effects ’ .","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","external_id":{"arxiv":["1505.03178"],"isi":["000378862800006"]},"corr_author":"1","scopus_import":"1","issue":"7","main_file_link":[{"url":"https://arxiv.org/abs/1505.03178","open_access":"1"}],"page":"1992 - 2023","abstract":[{"lang":"eng","text":"We consider a non-standard finite-volume discretization of a strongly non-linear fourth order diffusion equation on the d-dimensional cube, for arbitrary . The scheme preserves two important structural properties of the equation: the first is the interpretation as a gradient flow in a mass transportation metric, and the second is an intimate relation to a linear Fokker-Planck equation. Thanks to these structural properties, the scheme possesses two discrete Lyapunov functionals. These functionals approximate the entropy and the Fisher information, respectively, and their dissipation rates converge to the optimal ones in the discrete-to-continuous limit. Using the dissipation, we derive estimates on the long-time asymptotics of the discrete solutions. Finally, we present results from numerical experiments which indicate that our discretization is able to capture significant features of the complex original dynamics, even with a rather coarse spatial resolution."}],"date_updated":"2025-09-22T09:00:50Z","author":[{"orcid":"0000-0002-0845-1338","last_name":"Maas","full_name":"Maas, Jan","first_name":"Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Daniel","full_name":"Matthes, Daniel","last_name":"Matthes"}],"article_processing_charge":"No","year":"2016","arxiv":1,"oa_version":"Preprint"},{"date_created":"2023-02-20T08:14:28Z","publisher":"American Geophysical Union","intvolume":" 121","type":"journal_article","citation":{"ista":"Buri P, Miles ES, Steiner JF, Immerzeel WW, Wagnon P, Pellicciotti F. 2016. A physically based 3‐D model of ice cliff evolution over debris‐covered glaciers. Journal of Geophysical Research: Earth Surface. 121(12), 2471–2493.","mla":"Buri, Pascal, et al. “A Physically Based 3‐D Model of Ice Cliff Evolution over Debris‐covered Glaciers.” Journal of Geophysical Research: Earth Surface, vol. 121, no. 12, American Geophysical Union, 2016, pp. 2471–93, doi:10.1002/2016jf004039.","chicago":"Buri, Pascal, Evan S. Miles, Jakob F. Steiner, Walter W. Immerzeel, Patrick Wagnon, and Francesca Pellicciotti. “A Physically Based 3‐D Model of Ice Cliff Evolution over Debris‐covered Glaciers.” Journal of Geophysical Research: Earth Surface. American Geophysical Union, 2016. https://doi.org/10.1002/2016jf004039.","ieee":"P. Buri, E. S. Miles, J. F. Steiner, W. W. Immerzeel, P. Wagnon, and F. Pellicciotti, “A physically based 3‐D model of ice cliff evolution over debris‐covered glaciers,” Journal of Geophysical Research: Earth Surface, vol. 121, no. 12. American Geophysical Union, pp. 2471–2493, 2016.","apa":"Buri, P., Miles, E. S., Steiner, J. F., Immerzeel, W. W., Wagnon, P., & Pellicciotti, F. (2016). A physically based 3‐D model of ice cliff evolution over debris‐covered glaciers. Journal of Geophysical Research: Earth Surface. American Geophysical Union. https://doi.org/10.1002/2016jf004039","short":"P. Buri, E.S. Miles, J.F. Steiner, W.W. Immerzeel, P. Wagnon, F. Pellicciotti, Journal of Geophysical Research: Earth Surface 121 (2016) 2471–2493.","ama":"Buri P, Miles ES, Steiner JF, Immerzeel WW, Wagnon P, Pellicciotti F. A physically based 3‐D model of ice cliff evolution over debris‐covered glaciers. Journal of Geophysical Research: Earth Surface. 2016;121(12):2471-2493. doi:10.1002/2016jf004039"},"publication_status":"published","day":"22","doi":"10.1002/2016jf004039","date_published":"2016-11-22T00:00:00Z","oa":1,"publication":"Journal of Geophysical Research: Earth Surface","language":[{"iso":"eng"}],"issue":"12","scopus_import":"1","keyword":["Earth-Surface Processes","Geophysics"],"publication_identifier":{"issn":["2169-9003"],"eissn":["2169-9011"]},"extern":"1","oa_version":"Published Version","date_updated":"2023-02-24T11:34:54Z","abstract":[{"lang":"eng","text":"We use high-resolution digital elevation models (DEMs) from unmanned aerial vehicle (UAV) surveys to document the evolution of four ice cliffs on the debris-covered tongue of Lirung Glacier, Nepal, over one ablation season. Observations show that out of four cliffs, three different patterns of evolution emerge: (i) reclining cliffs that flatten during the ablation season; (ii) stable cliffs that maintain a self-similar geometry; and (iii) growing cliffs, expanding laterally. We use the insights from this unique data set to develop a 3-D model of cliff backwasting and evolution that is validated against observations and an independent data set of volume losses. The model includes ablation at the cliff surface driven by energy exchange with the atmosphere, reburial of cliff cells by surrounding debris, and the effect of adjacent ponds. The cliff geometry is updated monthly to account for the modifications induced by each of those processes. Model results indicate that a major factor affecting the survival of steep cliffs is the coupling with ponded water at its base, which prevents progressive flattening and possible disappearance of a cliff. The radial growth observed at one cliff is explained by higher receipts of longwave and shortwave radiation, calculated taking into account atmospheric fluxes, shading, and the emission of longwave radiation from debris surfaces. The model is a clear step forward compared to existing static approaches that calculate atmospheric melt over an invariant cliff geometry and can be used for long-term simulations of cliff evolution and to test existing hypotheses about cliffs' survival."}],"author":[{"full_name":"Buri, Pascal","first_name":"Pascal","last_name":"Buri"},{"first_name":"Evan S.","full_name":"Miles, Evan S.","last_name":"Miles"},{"last_name":"Steiner","full_name":"Steiner, Jakob F.","first_name":"Jakob F."},{"first_name":"Walter W.","full_name":"Immerzeel, Walter W.","last_name":"Immerzeel"},{"last_name":"Wagnon","first_name":"Patrick","full_name":"Wagnon, Patrick"},{"last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"year":"2016","article_processing_charge":"No","article_type":"original","main_file_link":[{"url":"https://doi.org/10.1002/2016JF004039","open_access":"1"}],"page":"2471-2493","quality_controlled":"1","month":"11","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12613","title":"A physically based 3‐D model of ice cliff evolution over debris‐covered glaciers","volume":121,"status":"public"},{"intvolume":" 186","oa_version":"None","publisher":"Elsevier","author":[{"first_name":"P.D.A.","full_name":"Kraaijenbrink, P.D.A.","last_name":"Kraaijenbrink"},{"last_name":"Shea","full_name":"Shea, J.M.","first_name":"J.M."},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca","full_name":"Pellicciotti, Francesca"},{"last_name":"Jong","full_name":"Jong, S.M. de","first_name":"S.M. de"},{"last_name":"Immerzeel","first_name":"W.W.","full_name":"Immerzeel, W.W."}],"article_processing_charge":"No","year":"2016","type":"journal_article","abstract":[{"text":"Debris-covered glaciers in the Himalaya may have spatially-averaged rates of surface height change that are similar to those observed on bare-ice glaciers, despite the insulating effects of thick debris. Spatially heterogeneous melt patterns caused by the development and evolution of ice cliffs and supraglacial pond systems result in substantial mass losses over time. However, mechanisms controlling the formation and survival of cliffs and ponds remain largely unknown. To study the distribution and characteristics of these surface features we deploy an unmanned aerial vehicle (UAV) over a stretch of the debris-covered Langtang Glacier, Nepal. Acquired images are processed into high-resolution orthomosaics and elevation models with the Structure from Motion (SfM) photogrammetry algorithm. Ice cliffs and ponds are classified using object-based image analysis (OBIA) and their morphology and spatial distribution are analysed and evaluated using object, pixel and point cloud approaches. Results show that ice cliffs are predominantly north-facing, and larger ice cliffs are generally coupled with supraglacial ponds, which may affect their evolution considerably. The spatial distribution of ice cliffs indicates that they are more likely to form in areas where high strain rates are expected. The spatial configuration of ponds over the entire tongue reveals high pond density near confluences, possibly due to closure of conduits via transverse compression. We conclude that the combination of OBIA and UAV imagery is a valuable tool in the semi-automatic and objective analysis of surface features on debris-covered glaciers. The technique may also have potential for upscaling to the use of spaceborne imagery, and the use of UAV-derived point clouds to analyse ice cliff undercuts is promising.","lang":"eng"}],"date_updated":"2023-02-24T11:31:58Z","citation":{"short":"P.D.A. Kraaijenbrink, J.M. Shea, F. Pellicciotti, S.M. de Jong, W.W. Immerzeel, Remote Sensing of Environment 186 (2016) 581–595.","ama":"Kraaijenbrink PDA, Shea JM, Pellicciotti F, Jong SM de, Immerzeel WW. Object-based analysis of unmanned aerial vehicle imagery to map and characterise surface features on a debris-covered glacier. Remote Sensing of Environment. 2016;186:581-595. doi:10.1016/j.rse.2016.09.013","apa":"Kraaijenbrink, P. D. A., Shea, J. M., Pellicciotti, F., Jong, S. M. de, & Immerzeel, W. W. (2016). Object-based analysis of unmanned aerial vehicle imagery to map and characterise surface features on a debris-covered glacier. Remote Sensing of Environment. Elsevier. https://doi.org/10.1016/j.rse.2016.09.013","mla":"Kraaijenbrink, P. D. A., et al. “Object-Based Analysis of Unmanned Aerial Vehicle Imagery to Map and Characterise Surface Features on a Debris-Covered Glacier.” Remote Sensing of Environment, vol. 186, Elsevier, 2016, pp. 581–95, doi:10.1016/j.rse.2016.09.013.","ista":"Kraaijenbrink PDA, Shea JM, Pellicciotti F, Jong SM de, Immerzeel WW. 2016. Object-based analysis of unmanned aerial vehicle imagery to map and characterise surface features on a debris-covered glacier. Remote Sensing of Environment. 186, 581–595.","ieee":"P. D. A. Kraaijenbrink, J. M. Shea, F. Pellicciotti, S. M. de Jong, and W. W. Immerzeel, “Object-based analysis of unmanned aerial vehicle imagery to map and characterise surface features on a debris-covered glacier,” Remote Sensing of Environment, vol. 186. Elsevier, pp. 581–595, 2016.","chicago":"Kraaijenbrink, P.D.A., J.M. Shea, Francesca Pellicciotti, S.M. de Jong, and W.W. Immerzeel. “Object-Based Analysis of Unmanned Aerial Vehicle Imagery to Map and Characterise Surface Features on a Debris-Covered Glacier.” Remote Sensing of Environment. Elsevier, 2016. https://doi.org/10.1016/j.rse.2016.09.013."},"article_type":"original","page":"581-595","scopus_import":"1","publication_identifier":{"issn":["0034-4257"]},"keyword":["Computers in Earth Sciences","Geology","Soil Science"],"extern":"1","date_created":"2023-02-20T08:14:35Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12614","date_published":"2016-12-01T00:00:00Z","doi":"10.1016/j.rse.2016.09.013","volume":186,"publication":"Remote Sensing of Environment","title":"Object-based analysis of unmanned aerial vehicle imagery to map and characterise surface features on a debris-covered glacier","status":"public","language":[{"iso":"eng"}],"month":"12","quality_controlled":"1","publication_status":"published","day":"01"},{"extern":"1","keyword":["Water Science and Technology"],"publication_identifier":{"issn":["0885-6087"]},"scopus_import":"1","issue":"22","page":"4036-4058","article_type":"original","author":[{"first_name":"A.","full_name":"Ayala, A.","last_name":"Ayala"},{"last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"},{"full_name":"MacDonell, S.","first_name":"S.","last_name":"MacDonell"},{"full_name":"McPhee, J.","first_name":"J.","last_name":"McPhee"},{"last_name":"Vivero","first_name":"S.","full_name":"Vivero, S."},{"first_name":"C.","full_name":"Campos, C.","last_name":"Campos"},{"first_name":"P.","full_name":"Egli, P.","last_name":"Egli"}],"article_processing_charge":"No","year":"2016","date_updated":"2023-02-24T11:29:28Z","abstract":[{"lang":"eng","text":"We apply the process-based, distributed TOPKAPI-ETH glacio-hydrological model to a glacierized catchment (19% glacierized) in the semiarid Andes of central Chile. The semiarid Andes provides vital freshwater resources to valleys in Chile and Argentina, but only few glacio-hydrological modelling studies have been conducted, and its dominant hydrological processes remain poorly understood. The catchment contains two debris-free glaciers reaching down to 3900 m asl (Bello and Yeso glaciers) and one debris-covered avalanche-fed glacier reaching to 3200 m asl (Piramide Glacier). Our main objective is to compare the mass balance and runoff contributions of both glacier types under current climatic conditions. We use a unique dataset of field measurements collected over two ablation seasons combined with the distributed TOPKAPI-ETH model that includes physically oriented parameterizations of snow and ice ablation, gravitational distribution of snow, snow albedo evolution and the ablation of debris-covered ice. Model outputs indicate that while the mass balance of Bello and Yeso glaciers is mostly explained by temperature gradients, the Piramide Glacier mass balance is governed by debris thickness and avalanches and has a clear non-linear profile with elevation as a result. Despite the thermal insulation effect of the debris cover, the mass balance and contribution to runoff from debris-free and debris-covered glaciers are similar in magnitude, mainly because of elevation differences. However, runoff contributions are distinct in time and seasonality with ice melt starting approximately four weeks earlier from the debris-covered glacier, what is of relevance for water resources management. At the catchment scale, snowmelt is the dominant contributor to runoff during both years. However, during the driest year of our simulations, ice melt contributes 42 ± 8% and 67 ± 6% of the annual and summer runoff, respectively. Sensitivity analyses show that runoff is most sensitive to temperature and precipitation gradients, melt factors and debris cover thickness. "}],"oa_version":"None","month":"07","quality_controlled":"1","status":"public","volume":30,"title":"Modelling the hydrological response of debris-free and debris-covered glaciers to present climatic conditions in the semiarid Andes of central Chile","_id":"12615","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-02-20T08:14:40Z","citation":{"ista":"Ayala A, Pellicciotti F, MacDonell S, McPhee J, Vivero S, Campos C, Egli P. 2016. Modelling the hydrological response of debris-free and debris-covered glaciers to present climatic conditions in the semiarid Andes of central Chile. Hydrological Processes. 30(22), 4036–4058.","mla":"Ayala, A., et al. “Modelling the Hydrological Response of Debris-Free and Debris-Covered Glaciers to Present Climatic Conditions in the Semiarid Andes of Central Chile.” Hydrological Processes, vol. 30, no. 22, Wiley, 2016, pp. 4036–58, doi:10.1002/hyp.10971.","ieee":"A. Ayala et al., “Modelling the hydrological response of debris-free and debris-covered glaciers to present climatic conditions in the semiarid Andes of central Chile,” Hydrological Processes, vol. 30, no. 22. Wiley, pp. 4036–4058, 2016.","chicago":"Ayala, A., Francesca Pellicciotti, S. MacDonell, J. McPhee, S. Vivero, C. Campos, and P. Egli. “Modelling the Hydrological Response of Debris-Free and Debris-Covered Glaciers to Present Climatic Conditions in the Semiarid Andes of Central Chile.” Hydrological Processes. Wiley, 2016. https://doi.org/10.1002/hyp.10971.","apa":"Ayala, A., Pellicciotti, F., MacDonell, S., McPhee, J., Vivero, S., Campos, C., & Egli, P. (2016). Modelling the hydrological response of debris-free and debris-covered glaciers to present climatic conditions in the semiarid Andes of central Chile. Hydrological Processes. Wiley. https://doi.org/10.1002/hyp.10971","short":"A. Ayala, F. Pellicciotti, S. MacDonell, J. McPhee, S. Vivero, C. Campos, P. Egli, Hydrological Processes 30 (2016) 4036–4058.","ama":"Ayala A, Pellicciotti F, MacDonell S, et al. Modelling the hydrological response of debris-free and debris-covered glaciers to present climatic conditions in the semiarid Andes of central Chile. Hydrological Processes. 2016;30(22):4036-4058. doi:10.1002/hyp.10971"},"type":"journal_article","intvolume":" 30","publisher":"Wiley","day":"28","publication_status":"published","language":[{"iso":"eng"}],"publication":"Hydrological Processes","date_published":"2016-07-28T00:00:00Z","doi":"10.1002/hyp.10971"},{"article_processing_charge":"No","author":[{"last_name":"Rodriguez","first_name":"Maximiliano","full_name":"Rodriguez, Maximiliano"},{"last_name":"Ohlanders","first_name":"Nils","full_name":"Ohlanders, Nils"},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca"},{"last_name":"Williams","first_name":"Mark W.","full_name":"Williams, Mark W."},{"last_name":"McPhee","full_name":"McPhee, James","first_name":"James"}],"year":"2016","date_updated":"2023-02-24T11:26:54Z","abstract":[{"lang":"eng","text":"This paper presents a methodology for hydrograph separation in mountain watersheds, which aims at identifying flow sources among ungauged headwater sub-catchments through a combination of observed streamflow and data on natural tracers including isotope and dissolved solids. Daily summer and bi-daily spring season water samples obtained at the outlet of the Juncal River Basin in the Andes of Central Chile were analysed for all major ions as well as stable water isotopes, δ18O and δD. Additionally, various samples from rain, snow, surface streams and exfiltrating subsurface water (springs) were sampled throughout the catchment. A principal component analysis was performed in order to address cross-correlation in the tracer dataset, reduce the dimensionality of the problem and uncover patterns of variability. Potential sources were identified in a two-component U-space that explains 94% of the observed tracer variability at the catchment outlet. Hydrograph separation was performed through an Informative-Bayesian model. Our results indicate that the Juncal Norte Glacier headwater sub-catchment contributed at least 50% of summer flows at the Juncal River Basin outlet during the 2011–2012 water year (a hydrologically dry period in the Region), even though it accounts for only 27% of the basin area. Our study confirms the value of combining solute and isotope information for estimating source contributions in complex hydrologic systems, and provides insights regarding experimental design in high-elevation semi-arid catchments. The findings of this study can be useful for evaluating modelling studies of the hydrological consequences of the rapid decrease in glacier cover observed in this region, by providing insights into the origin of river water in basins with little hydrometeorological information."}],"oa_version":"None","page":"3609-3626","article_type":"original","publication_identifier":{"issn":["0885-6087"]},"keyword":["Water Science and Technology"],"scopus_import":"1","issue":"20","extern":"1","_id":"12616","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","volume":30,"title":"Estimating runoff from a glacierized catchment using natural tracers in the semi-arid Andes cordillera","month":"07","quality_controlled":"1","type":"journal_article","intvolume":" 30","publisher":"Wiley","citation":{"ieee":"M. Rodriguez, N. Ohlanders, F. Pellicciotti, M. W. Williams, and J. McPhee, “Estimating runoff from a glacierized catchment using natural tracers in the semi-arid Andes cordillera,” Hydrological Processes, vol. 30, no. 20. Wiley, pp. 3609–3626, 2016.","chicago":"Rodriguez, Maximiliano, Nils Ohlanders, Francesca Pellicciotti, Mark W. Williams, and James McPhee. “Estimating Runoff from a Glacierized Catchment Using Natural Tracers in the Semi-Arid Andes Cordillera.” Hydrological Processes. Wiley, 2016. https://doi.org/10.1002/hyp.10973.","mla":"Rodriguez, Maximiliano, et al. “Estimating Runoff from a Glacierized Catchment Using Natural Tracers in the Semi-Arid Andes Cordillera.” Hydrological Processes, vol. 30, no. 20, Wiley, 2016, pp. 3609–26, doi:10.1002/hyp.10973.","ista":"Rodriguez M, Ohlanders N, Pellicciotti F, Williams MW, McPhee J. 2016. Estimating runoff from a glacierized catchment using natural tracers in the semi-arid Andes cordillera. Hydrological Processes. 30(20), 3609–3626.","ama":"Rodriguez M, Ohlanders N, Pellicciotti F, Williams MW, McPhee J. Estimating runoff from a glacierized catchment using natural tracers in the semi-arid Andes cordillera. Hydrological Processes. 2016;30(20):3609-3626. doi:10.1002/hyp.10973","short":"M. Rodriguez, N. Ohlanders, F. Pellicciotti, M.W. Williams, J. McPhee, Hydrological Processes 30 (2016) 3609–3626.","apa":"Rodriguez, M., Ohlanders, N., Pellicciotti, F., Williams, M. W., & McPhee, J. (2016). Estimating runoff from a glacierized catchment using natural tracers in the semi-arid Andes cordillera. Hydrological Processes. Wiley. https://doi.org/10.1002/hyp.10973"},"date_created":"2023-02-20T08:14:45Z","date_published":"2016-07-22T00:00:00Z","doi":"10.1002/hyp.10973","language":[{"iso":"eng"}],"publication":"Hydrological Processes","publication_status":"published","day":"22"},{"quality_controlled":"1","month":"09","_id":"12617","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","title":"Heterogeneous glacier thinning patterns over the last 40 years in Langtang Himal, Nepal","volume":10,"publication_identifier":{"issn":["1994-0424"]},"keyword":["Earth-Surface Processes","Water Science and Technology"],"scopus_import":"1","issue":"5","extern":"1","abstract":[{"lang":"eng","text":"This study presents volume and mass changes of seven (five partially debris-covered, two debris-free) glaciers in the upper Langtang catchment in Nepal. We use a digital elevation model (DEM) from 1974 stereo Hexagon satellite data and seven DEMs derived from 2006–2015 stereo or tri-stereo satellite imagery (e.g., SPOT6/7). The availability of multiple independent DEM differences allows the identification of a robust signal and narrowing down of the uncertainty about recent volume changes. The volume changes calculated over several multiyear periods between 2006 and 2015 consistently indicate that glacier thinning has accelerated with respect to the period 1974–2006. We calculate an ensemble-mean elevation change rate of –0.45 ± 0.18 m a−1 for 2006–2015, while for the period 1974–2006 we compute a rate of −0.24 ± 0.08 m a−1. However, the behavior of glaciers in the study area is heterogeneous, and the presence or absence of debris does not seem to be a good predictor for mass balance trends. Debris-covered tongues have nonlinear thinning profiles, and we show that recent accelerations in thinning correlate with the presence of supraglacial cliffs and lakes. At stagnating glacier areas near the glacier front, however, thinning rates decreased with time or remained constant. The April 2015 Nepal earthquake triggered large avalanches in the study catchment. Analysis of two post-earthquake DEMs revealed that the avalanche deposit volumes remaining 6 months after the earthquake are negligible in comparison to 2006–2015 elevation changes. However, the deposits compensate about 40 % the mass loss of debris-covered tongues of 1 average year."}],"date_updated":"2023-02-24T10:54:02Z","author":[{"first_name":"Silvan","full_name":"Ragettli, Silvan","last_name":"Ragettli"},{"last_name":"Bolch","full_name":"Bolch, Tobias","first_name":"Tobias"},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca","last_name":"Pellicciotti"}],"article_processing_charge":"No","year":"2016","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.5194/tc-10-2075-2016","open_access":"1"}],"page":"2075-2097","article_type":"original","publication_status":"published","day":"14","doi":"10.5194/tc-10-2075-2016","date_published":"2016-09-14T00:00:00Z","oa":1,"language":[{"iso":"eng"}],"publication":"The Cryosphere","date_created":"2023-02-20T08:14:51Z","type":"journal_article","publisher":"Copernicus Publications","intvolume":" 10","citation":{"ista":"Ragettli S, Bolch T, Pellicciotti F. 2016. Heterogeneous glacier thinning patterns over the last 40 years in Langtang Himal, Nepal. The Cryosphere. 10(5), 2075–2097.","mla":"Ragettli, Silvan, et al. “Heterogeneous Glacier Thinning Patterns over the Last 40 Years in Langtang Himal, Nepal.” The Cryosphere, vol. 10, no. 5, Copernicus Publications, 2016, pp. 2075–97, doi:10.5194/tc-10-2075-2016.","chicago":"Ragettli, Silvan, Tobias Bolch, and Francesca Pellicciotti. “Heterogeneous Glacier Thinning Patterns over the Last 40 Years in Langtang Himal, Nepal.” The Cryosphere. Copernicus Publications, 2016. https://doi.org/10.5194/tc-10-2075-2016.","ieee":"S. Ragettli, T. Bolch, and F. Pellicciotti, “Heterogeneous glacier thinning patterns over the last 40 years in Langtang Himal, Nepal,” The Cryosphere, vol. 10, no. 5. Copernicus Publications, pp. 2075–2097, 2016.","apa":"Ragettli, S., Bolch, T., & Pellicciotti, F. (2016). Heterogeneous glacier thinning patterns over the last 40 years in Langtang Himal, Nepal. The Cryosphere. Copernicus Publications. https://doi.org/10.5194/tc-10-2075-2016","short":"S. Ragettli, T. Bolch, F. Pellicciotti, The Cryosphere 10 (2016) 2075–2097.","ama":"Ragettli S, Bolch T, Pellicciotti F. Heterogeneous glacier thinning patterns over the last 40 years in Langtang Himal, Nepal. The Cryosphere. 2016;10(5):2075-2097. doi:10.5194/tc-10-2075-2016"}},{"date_created":"2023-02-20T08:14:58Z","intvolume":" 113","publisher":"Proceedings of the National Academy of Sciences","type":"journal_article","citation":{"short":"S. Ragettli, W.W. Immerzeel, F. Pellicciotti, PNAS 113 (2016) 9222–9227.","ama":"Ragettli S, Immerzeel WW, Pellicciotti F. Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains. PNAS. 2016;113(33):9222-9227. doi:10.1073/pnas.1606526113","apa":"Ragettli, S., Immerzeel, W. W., & Pellicciotti, F. (2016). Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains. PNAS. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1606526113","mla":"Ragettli, Silvan, et al. “Contrasting Climate Change Impact on River Flows from High-Altitude Catchments in the Himalayan and Andes Mountains.” PNAS, vol. 113, no. 33, Proceedings of the National Academy of Sciences, 2016, pp. 9222–27, doi:10.1073/pnas.1606526113.","ista":"Ragettli S, Immerzeel WW, Pellicciotti F. 2016. Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains. PNAS. 113(33), 9222–9227.","chicago":"Ragettli, Silvan, Walter W. Immerzeel, and Francesca Pellicciotti. “Contrasting Climate Change Impact on River Flows from High-Altitude Catchments in the Himalayan and Andes Mountains.” PNAS. Proceedings of the National Academy of Sciences, 2016. https://doi.org/10.1073/pnas.1606526113.","ieee":"S. Ragettli, W. W. Immerzeel, and F. Pellicciotti, “Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains,” PNAS, vol. 113, no. 33. Proceedings of the National Academy of Sciences, pp. 9222–9227, 2016."},"publication_status":"published","day":"01","date_published":"2016-08-01T00:00:00Z","oa":1,"doi":"10.1073/pnas.1606526113","publication":"PNAS","language":[{"iso":"eng"}],"scopus_import":"1","issue":"33","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"keyword":["Multidisciplinary"],"extern":"1","external_id":{"pmid":["27482082"]},"oa_version":"Published Version","pmid":1,"year":"2016","author":[{"last_name":"Ragettli","full_name":"Ragettli, Silvan","first_name":"Silvan"},{"first_name":"Walter W.","full_name":"Immerzeel, Walter W.","last_name":"Immerzeel"},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca"}],"article_processing_charge":"No","abstract":[{"text":"Mountain ranges are the world’s natural water towers and provide water resources for millions of people. However, their hydrological balance and possible future changes in river flow remain poorly understood because of high meteorological variability, physical inaccessibility, and the complex interplay between climate, cryosphere, and hydrological processes. Here, we use a state-of-the art glacio-hydrological model informed by data from high-altitude observations and the latest climate change scenarios to quantify the climate change impact on water resources of two contrasting catchments vulnerable to changes in the cryosphere. The two study catchments are located in the Central Andes of Chile and in the Nepalese Himalaya in close vicinity of densely populated areas. Although both sites reveal a strong decrease in glacier area, they show a remarkably different hydrological response to projected climate change. In the Juncal catchment in Chile, runoff is likely to sharply decrease in the future and the runoff seasonality is sensitive to projected climatic changes. In the Langtang catchment in Nepal, future water availability is on the rise for decades to come with limited shifts between seasons. Owing to the high spatiotemporal resolution of the simulations and process complexity included in the modeling, the response times and the mechanisms underlying the variations in glacier area and river flow can be well constrained. The projections indicate that climate change adaptation in Central Chile should focus on dealing with a reduction in water availability, whereas in Nepal preparedness for flood extremes should be the policy priority.","lang":"eng"}],"date_updated":"2023-02-24T10:48:43Z","article_type":"original","page":"9222-9227","main_file_link":[{"url":"https://doi.org/10.1073/pnas.1606526113","open_access":"1"}],"month":"08","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12618","volume":113,"title":"Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains","status":"public"},{"doi":"10.1017/jog.2016.54","oa":1,"date_published":"2016-08-01T00:00:00Z","publication":"Journal of Glaciology","language":[{"iso":"eng"}],"publication_status":"published","day":"01","publisher":"Cambridge University Press","intvolume":" 62","type":"journal_article","citation":{"ieee":"F. BRUN et al., “Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry,” Journal of Glaciology, vol. 62, no. 234. Cambridge University Press, pp. 684–695, 2016.","chicago":"BRUN, FANNY, PASCAL BURI, EVAN S. MILES, PATRICK WAGNON, JAKOB STEINER, ETIENNE BERTHIER, SILVAN RAGETTLI, PHILIP KRAAIJENBRINK, WALTER W. IMMERZEEL, and Francesca Pellicciotti. “Quantifying Volume Loss from Ice Cliffs on Debris-Covered Glaciers Using High-Resolution Terrestrial and Aerial Photogrammetry.” Journal of Glaciology. Cambridge University Press, 2016. https://doi.org/10.1017/jog.2016.54.","ista":"BRUN F, BURI P, MILES ES, WAGNON P, STEINER J, BERTHIER E, RAGETTLI S, KRAAIJENBRINK P, IMMERZEEL WW, Pellicciotti F. 2016. Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry. Journal of Glaciology. 62(234), 684–695.","mla":"BRUN, FANNY, et al. “Quantifying Volume Loss from Ice Cliffs on Debris-Covered Glaciers Using High-Resolution Terrestrial and Aerial Photogrammetry.” Journal of Glaciology, vol. 62, no. 234, Cambridge University Press, 2016, pp. 684–95, doi:10.1017/jog.2016.54.","apa":"BRUN, F., BURI, P., MILES, E. S., WAGNON, P., STEINER, J., BERTHIER, E., … Pellicciotti, F. (2016). Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry. Journal of Glaciology. Cambridge University Press. https://doi.org/10.1017/jog.2016.54","ama":"BRUN F, BURI P, MILES ES, et al. Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry. Journal of Glaciology. 2016;62(234):684-695. doi:10.1017/jog.2016.54","short":"F. BRUN, P. BURI, E.S. MILES, P. WAGNON, J. STEINER, E. BERTHIER, S. RAGETTLI, P. KRAAIJENBRINK, W.W. IMMERZEEL, F. Pellicciotti, Journal of Glaciology 62 (2016) 684–695."},"date_created":"2023-02-20T08:15:06Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12619","title":"Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry","volume":62,"status":"public","quality_controlled":"1","month":"08","oa_version":"Published Version","abstract":[{"text":"Mass losses originating from supraglacial ice cliffs at the lower tongues of debris-covered glaciers are a potentially large component of the mass balance, but have rarely been quantified. In this study, we develop a method to estimate ice cliff volume losses based on high-resolution topographic data derived from terrestrial and aerial photogrammetry. We apply our method to six cliffs monitored in May and October 2013 and 2014 using four different topographic datasets collected over the debris-covered Lirung Glacier of the Nepalese Himalayas. During the monsoon, the cliff mean backwasting rate was relatively consistent in 2013 (3.8 ± 0.3 cm w.e. d−1) and more heterogeneous among cliffs in 2014 (3.1 ± 0.7 cm w.e. d−1), and the geometric variations between cliffs are larger. Their mean backwasting rate is significantly lower in winter (October 2013–May 2014), at 1.0 ± 0.3 cm w.e. d−1. These results are consistent with estimates of cliff ablation from an energy-balance model developed in a previous study. The ice cliffs lose mass at rates six times higher than estimates of glacier-wide melt under debris, which seems to confirm that ice cliffs provide a large contribution to total glacier melt.","lang":"eng"}],"date_updated":"2023-02-24T10:36:55Z","article_processing_charge":"No","author":[{"first_name":"FANNY","full_name":"BRUN, FANNY","last_name":"BRUN"},{"first_name":"PASCAL","full_name":"BURI, PASCAL","last_name":"BURI"},{"full_name":"MILES, EVAN S.","first_name":"EVAN S.","last_name":"MILES"},{"full_name":"WAGNON, PATRICK","first_name":"PATRICK","last_name":"WAGNON"},{"first_name":"JAKOB","full_name":"STEINER, JAKOB","last_name":"STEINER"},{"first_name":"ETIENNE","full_name":"BERTHIER, ETIENNE","last_name":"BERTHIER"},{"last_name":"RAGETTLI","first_name":"SILVAN","full_name":"RAGETTLI, SILVAN"},{"last_name":"KRAAIJENBRINK","first_name":"PHILIP","full_name":"KRAAIJENBRINK, PHILIP"},{"last_name":"IMMERZEEL","full_name":"IMMERZEEL, WALTER W.","first_name":"WALTER W."},{"last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"year":"2016","article_type":"original","main_file_link":[{"url":"https://doi.org/10.1017/jog.2016.54","open_access":"1"}],"page":"684-695","issue":"234","scopus_import":"1","publication_identifier":{"eissn":["1727-5652"],"issn":["0022-1430"]},"keyword":["Earth-Surface Processes"],"extern":"1"},{"citation":{"short":"D. Mcmahon, M. Natsopoulou, V. Doublet, M. Fürst, S. Weging, M. Brown, A. Gogol Döring, R. Paxton, Proceedings of the Royal Society of London Series B Biological Sciences 283 (2016).","ama":"Mcmahon D, Natsopoulou M, Doublet V, et al. Elevated virulence of an emerging viral genotype as a driver of honeybee loss. Proceedings of the Royal Society of London Series B Biological Sciences. 2016;283(1833). doi:10.1098/rspb.2016.0811","apa":"Mcmahon, D., Natsopoulou, M., Doublet, V., Fürst, M., Weging, S., Brown, M., … Paxton, R. (2016). Elevated virulence of an emerging viral genotype as a driver of honeybee loss. Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The. https://doi.org/10.1098/rspb.2016.0811","ista":"Mcmahon D, Natsopoulou M, Doublet V, Fürst M, Weging S, Brown M, Gogol Döring A, Paxton R. 2016. Elevated virulence of an emerging viral genotype as a driver of honeybee loss. Proceedings of the Royal Society of London Series B Biological Sciences. 283(1833), 20160811.","mla":"Mcmahon, Dino, et al. “Elevated Virulence of an Emerging Viral Genotype as a Driver of Honeybee Loss.” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 283, no. 1833, 20160811, Royal Society, The, 2016, doi:10.1098/rspb.2016.0811.","ieee":"D. Mcmahon et al., “Elevated virulence of an emerging viral genotype as a driver of honeybee loss,” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 283, no. 1833. Royal Society, The, 2016.","chicago":"Mcmahon, Dino, Myrsini Natsopoulou, Vincent Doublet, Matthias Fürst, Silvio Weging, Mark Brown, Andreas Gogol Döring, and Robert Paxton. “Elevated Virulence of an Emerging Viral Genotype as a Driver of Honeybee Loss.” Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The, 2016. https://doi.org/10.1098/rspb.2016.0811."},"department":[{"_id":"SyCr"}],"type":"journal_article","intvolume":" 283","isi":1,"publisher":"Royal Society, The","date_created":"2018-12-11T11:51:00Z","pubrep_id":"701","language":[{"iso":"eng"}],"file":[{"file_id":"4708","date_updated":"2020-07-14T12:44:42Z","creator":"system","access_level":"open_access","content_type":"application/pdf","date_created":"2018-12-12T10:08:46Z","file_size":796872,"relation":"main_file","checksum":"0b0d1be38b497d004064650acb3baced","file_name":"IST-2016-701-v1+1_20160811.full.pdf"}],"file_date_updated":"2020-07-14T12:44:42Z","publication":"Proceedings of the Royal Society of London Series B Biological Sciences","oa":1,"date_published":"2016-06-29T00:00:00Z","doi":"10.1098/rspb.2016.0811","day":"29","publication_status":"published","article_number":"20160811","related_material":{"record":[{"relation":"research_data","id":"9704","status":"public"}]},"year":"2016","author":[{"last_name":"Mcmahon","full_name":"Mcmahon, Dino","first_name":"Dino"},{"last_name":"Natsopoulou","first_name":"Myrsini","full_name":"Natsopoulou, Myrsini"},{"last_name":"Doublet","full_name":"Doublet, Vincent","first_name":"Vincent"},{"last_name":"Fürst","orcid":"0000-0002-3712-925X","full_name":"Fürst, Matthias","first_name":"Matthias","id":"393B1196-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Weging","full_name":"Weging, Silvio","first_name":"Silvio"},{"last_name":"Brown","first_name":"Mark","full_name":"Brown, Mark"},{"last_name":"Gogol Döring","full_name":"Gogol Döring, Andreas","first_name":"Andreas"},{"full_name":"Paxton, Robert","first_name":"Robert","last_name":"Paxton"}],"article_processing_charge":"No","date_updated":"2025-09-22T08:59:30Z","abstract":[{"text":"Emerging infectious diseases (EIDs) have contributed significantly to the current biodiversity crisis, leading to widespread epidemics and population loss. Owing to genetic variation in pathogen virulence, a complete understanding of species decline requires the accurate identification and characterization of EIDs. We explore this issue in the Western honeybee, where increasing mortality of populations in the Northern Hemisphere has caused major concern. Specifically, we investigate the importance of genetic identity of the main suspect in mortality, deformed wing virus (DWV), in driving honeybee loss. Using laboratory experiments and a systematic field survey, we demonstrate that an emerging DWV genotype (DWV-B) is more virulent than the established DWV genotype (DWV-A) and is widespread in the landscape. Furthermore, we show in a simple model that colonies infected with DWV-B collapse sooner than colonies infected with DWV-A. We also identify potential for rapid DWV evolution by revealing extensive genome-wide recombination in vivo. The emergence of DWV-B in naive honeybee populations, including via recombination with DWV-A, could be of significant ecological and economic importance. Our findings emphasize that knowledge of pathogen genetic identity and diversity is critical to understanding drivers of species decline.","lang":"eng"}],"oa_version":"Published Version","has_accepted_license":"1","external_id":{"isi":["000381247300009"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"scopus_import":"1","issue":"1833","status":"public","volume":283,"title":"Elevated virulence of an emerging viral genotype as a driver of honeybee loss","_id":"1262","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"This work was supported by the Federal Ministry of Food, Agriculture and Consumer Protection (Germany): Fit Bee project (grant 511-06.01-28-1-71.007-10), the EU: BeeDoc (grant 244956), iDiv (2013 NGS-Fast Track grant W47004118) and the Insect Pollinators Initiative (IPI grant BB/I000100/1 and BB/I000151/1). The IPI is funded jointly by the Biotechnology and Biological Sciences Research Council, the Department for Environment, Food and Rural Affairs, the Natural Environment Research Council, the Scottish Government and the Wellcome Trust, under the Living with Environmental Change Partnership. We thank A. Abrahams, M. Husemann and A. Soro\r\nfor support in obtaining\r\nV. destructor\r\n-free honeybees; and BBKA\r\nPresident D. Aston for access to records of colony overwinter\r\n2011–2012 mortality in the UK. We also thank the anonymous refe-\r\nrees and Stephen Martin for comments that led to substantial\r\nimprovement of the manuscript.","publist_id":"6060","month":"06","ddc":["576","592"],"quality_controlled":"1"}]