[{"date_created":"2021-08-10T07:41:52Z","date_updated":"2025-07-10T12:01:48Z","type":"research_data_reference","_id":"9857","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","title":"Supporting information concerning observed wMel frequencies and analyses of habitat variables","author":[{"last_name":"Schmidt","full_name":"Schmidt, Tom","first_name":"Tom"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","last_name":"Barton","first_name":"Nicholas H","orcid":"0000-0002-8548-5240"},{"last_name":"Rasic","full_name":"Rasic, Gordana","first_name":"Gordana"},{"first_name":"Andrew","last_name":"Turley","full_name":"Turley, Andrew"},{"last_name":"Montgomery","full_name":"Montgomery, Brian","first_name":"Brian"},{"full_name":"Iturbe Ormaetxe, Inaki","last_name":"Iturbe Ormaetxe","first_name":"Inaki"},{"last_name":"Cook","full_name":"Cook, Peter","first_name":"Peter"},{"first_name":"Peter","full_name":"Ryan, Peter","last_name":"Ryan"},{"first_name":"Scott","full_name":"Ritchie, Scott","last_name":"Ritchie"},{"last_name":"Hoffmann","full_name":"Hoffmann, Ary","first_name":"Ary"},{"first_name":"Scott","last_name":"O’Neill","full_name":"O’Neill, Scott"},{"full_name":"Turelli, Michael","last_name":"Turelli","first_name":"Michael"}],"citation":{"apa":"Schmidt, T., Barton, N. H., Rasic, G., Turley, A., Montgomery, B., Iturbe Ormaetxe, I., … Turelli, M. (2017). Supporting information concerning observed wMel frequencies and analyses of habitat variables. Public Library of Science . <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s015\">https://doi.org/10.1371/journal.pbio.2001894.s015</a>","ama":"Schmidt T, Barton NH, Rasic G, et al. Supporting information concerning observed wMel frequencies and analyses of habitat variables. 2017. doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001894.s015\">10.1371/journal.pbio.2001894.s015</a>","ieee":"T. Schmidt <i>et al.</i>, “Supporting information concerning observed wMel frequencies and analyses of habitat variables.” Public Library of Science , 2017.","ista":"Schmidt T, Barton NH, Rasic G, Turley A, Montgomery B, Iturbe Ormaetxe I, Cook P, Ryan P, Ritchie S, Hoffmann A, O’Neill S, Turelli M. 2017. Supporting information concerning observed wMel frequencies and analyses of habitat variables, Public Library of Science , <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s015\">10.1371/journal.pbio.2001894.s015</a>.","mla":"Schmidt, Tom, et al. <i>Supporting Information Concerning Observed WMel Frequencies and Analyses of Habitat Variables</i>. Public Library of Science , 2017, doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001894.s015\">10.1371/journal.pbio.2001894.s015</a>.","chicago":"Schmidt, Tom, Nicholas H Barton, Gordana Rasic, Andrew Turley, Brian Montgomery, Inaki Iturbe Ormaetxe, Peter Cook, et al. “Supporting Information Concerning Observed WMel Frequencies and Analyses of Habitat Variables.” Public Library of Science , 2017. <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s015\">https://doi.org/10.1371/journal.pbio.2001894.s015</a>.","short":"T. Schmidt, N.H. Barton, G. Rasic, A. Turley, B. Montgomery, I. Iturbe Ormaetxe, P. Cook, P. Ryan, S. Ritchie, A. Hoffmann, S. O’Neill, M. Turelli, (2017)."},"publisher":"Public Library of Science ","status":"public","year":"2017","day":"30","doi":"10.1371/journal.pbio.2001894.s015","department":[{"_id":"NiBa"}],"month":"05","date_published":"2017-05-30T00:00:00Z","related_material":{"record":[{"status":"public","id":"951","relation":"used_in_publication"}]},"oa_version":"Published Version","article_processing_charge":"No"},{"citation":{"ieee":"T. Schmidt <i>et al.</i>, “Excel file with data on mosquito densities, Wolbachia infection status and housing characteristics.” Public Library of Science, 2017.","ama":"Schmidt T, Barton NH, Rasic G, et al. Excel file with data on mosquito densities, Wolbachia infection status and housing characteristics. 2017. doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001894.s016\">10.1371/journal.pbio.2001894.s016</a>","apa":"Schmidt, T., Barton, N. H., Rasic, G., Turley, A., Montgomery, B., Iturbe Ormaetxe, I., … Turelli, M. (2017). Excel file with data on mosquito densities, Wolbachia infection status and housing characteristics. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s016\">https://doi.org/10.1371/journal.pbio.2001894.s016</a>","mla":"Schmidt, Tom, et al. <i>Excel File with Data on Mosquito Densities, Wolbachia Infection Status and Housing Characteristics</i>. Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001894.s016\">10.1371/journal.pbio.2001894.s016</a>.","short":"T. Schmidt, N.H. Barton, G. Rasic, A. Turley, B. Montgomery, I. Iturbe Ormaetxe, P. Cook, P. Ryan, S. Ritchie, A. Hoffmann, S. O’Neill, M. Turelli, (2017).","chicago":"Schmidt, Tom, Nicholas H Barton, Gordana Rasic, Andrew Turley, Brian Montgomery, Inaki Iturbe Ormaetxe, Peter Cook, et al. “Excel File with Data on Mosquito Densities, Wolbachia Infection Status and Housing Characteristics.” Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s016\">https://doi.org/10.1371/journal.pbio.2001894.s016</a>.","ista":"Schmidt T, Barton NH, Rasic G, Turley A, Montgomery B, Iturbe Ormaetxe I, Cook P, Ryan P, Ritchie S, Hoffmann A, O’Neill S, Turelli M. 2017. Excel file with data on mosquito densities, Wolbachia infection status and housing characteristics, Public Library of Science, <a href=\"https://doi.org/10.1371/journal.pbio.2001894.s016\">10.1371/journal.pbio.2001894.s016</a>."},"status":"public","publisher":"Public Library of Science","year":"2017","department":[{"_id":"NiBa"}],"day":"30","doi":"10.1371/journal.pbio.2001894.s016","related_material":{"record":[{"relation":"used_in_publication","id":"951","status":"public"}]},"date_published":"2017-05-30T00:00:00Z","month":"05","oa_version":"Published Version","article_processing_charge":"No","date_created":"2021-08-10T07:47:07Z","type":"research_data_reference","date_updated":"2025-07-10T12:01:48Z","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","title":"Excel file with data on mosquito densities, Wolbachia infection status and housing characteristics","_id":"9858","author":[{"first_name":"Tom","full_name":"Schmidt, Tom","last_name":"Schmidt"},{"last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","first_name":"Nicholas H","orcid":"0000-0002-8548-5240"},{"first_name":"Gordana","full_name":"Rasic, Gordana","last_name":"Rasic"},{"full_name":"Turley, Andrew","last_name":"Turley","first_name":"Andrew"},{"last_name":"Montgomery","full_name":"Montgomery, Brian","first_name":"Brian"},{"first_name":"Inaki","full_name":"Iturbe Ormaetxe, Inaki","last_name":"Iturbe Ormaetxe"},{"last_name":"Cook","full_name":"Cook, Peter","first_name":"Peter"},{"full_name":"Ryan, Peter","last_name":"Ryan","first_name":"Peter"},{"first_name":"Scott","full_name":"Ritchie, Scott","last_name":"Ritchie"},{"first_name":"Ary","last_name":"Hoffmann","full_name":"Hoffmann, Ary"},{"first_name":"Scott","full_name":"O’Neill, Scott","last_name":"O’Neill"},{"first_name":"Michael","full_name":"Turelli, Michael","last_name":"Turelli"}]},{"month":"04","date_published":"2017-04-26T00:00:00Z","related_material":{"record":[{"relation":"used_in_publication","id":"1006","status":"public"}]},"doi":"10.6084/m9.figshare.c.3756974_d1.v1","day":"26","department":[{"_id":"SyCr"}],"article_processing_charge":"No","oa_version":"Published Version","publisher":"Springer Nature","status":"public","main_file_link":[{"url":"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1","open_access":"1"}],"citation":{"ista":"Greenwood J, Milutinovic B, Peuß R, Behrens S, Essar D, Rosenstiel P, Schulenburg H, Kurtz J. 2017. Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae, Springer Nature, <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1\">10.6084/m9.figshare.c.3756974_d1.v1</a>.","short":"J. Greenwood, B. Milutinovic, R. Peuß, S. Behrens, D. Essar, P. Rosenstiel, H. Schulenburg, J. Kurtz, (2017).","chicago":"Greenwood, Jenny, Barbara Milutinovic, Robert Peuß, Sarah Behrens, Daniela Essar, Philip Rosenstiel, Hinrich Schulenburg, and Joachim Kurtz. “Additional File 1: Table S1. of Oral Immune Priming with Bacillus Thuringiensis Induces a Shift in the Gene Expression of Tribolium Castaneum Larvae.” Springer Nature, 2017. <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1\">https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1</a>.","mla":"Greenwood, Jenny, et al. <i>Additional File 1: Table S1. of Oral Immune Priming with Bacillus Thuringiensis Induces a Shift in the Gene Expression of Tribolium Castaneum Larvae</i>. Springer Nature, 2017, doi:<a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1\">10.6084/m9.figshare.c.3756974_d1.v1</a>.","apa":"Greenwood, J., Milutinovic, B., Peuß, R., Behrens, S., Essar, D., Rosenstiel, P., … Kurtz, J. (2017). Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae. Springer Nature. <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1\">https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1</a>","ama":"Greenwood J, Milutinovic B, Peuß R, et al. Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae. 2017. doi:<a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d1.v1\">10.6084/m9.figshare.c.3756974_d1.v1</a>","ieee":"J. Greenwood <i>et al.</i>, “Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae.” Springer Nature, 2017."},"year":"2017","_id":"9859","title":"Additional file 1: Table S1. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","author":[{"last_name":"Greenwood","full_name":"Greenwood, Jenny","first_name":"Jenny"},{"orcid":"0000-0002-8214-4758","first_name":"Barbara","full_name":"Milutinovic, Barbara","id":"2CDC32B8-F248-11E8-B48F-1D18A9856A87","last_name":"Milutinovic"},{"first_name":"Robert","full_name":"Peuß, Robert","last_name":"Peuß"},{"full_name":"Behrens, Sarah","last_name":"Behrens","first_name":"Sarah"},{"first_name":"Daniela","full_name":"Essar, Daniela","last_name":"Essar"},{"last_name":"Rosenstiel","full_name":"Rosenstiel, Philip","first_name":"Philip"},{"first_name":"Hinrich","full_name":"Schulenburg, Hinrich","last_name":"Schulenburg"},{"first_name":"Joachim","full_name":"Kurtz, Joachim","last_name":"Kurtz"}],"oa":1,"abstract":[{"text":"Lists of all differentially expressed genes in the different priming-challenge treatments (compared to the fully naïve control; xlsx file). Relevant columns include the following: sample_1 and sample_2 – treatment groups being compared; Normalised FPKM sample_1 and sample_2 – FPKM of samples being compared; log2(fold_change) – log2(FPKM sample 2/FPKM sample 1), i.e. negative means sample 1 upregulated compared with sample 2, positive means sample 2 upregulated compared with sample 1; cuffdiff test_statistic – test statistic of differential expression test; p_value – p-value of differential expression test; q_value (FDR correction) – adjusted P-value of differential expression test. (XLSX 598 kb)","lang":"eng"}],"date_created":"2021-08-10T07:59:02Z","date_updated":"2025-07-10T11:49:39Z","type":"research_data_reference"},{"year":"2017","publisher":"Springer Nature","status":"public","main_file_link":[{"url":"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1","open_access":"1"}],"citation":{"ista":"Greenwood J, Milutinovic B, Peuß R, Behrens S, Essar D, Rosenstiel P, Schulenburg H, Kurtz J. 2017. Additional file 5: Table S3. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae, Springer Nature, <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1\">10.6084/m9.figshare.c.3756974_d5.v1</a>.","mla":"Greenwood, Jenny, et al. <i>Additional File 5: Table S3. of Oral Immune Priming with Bacillus Thuringiensis Induces a Shift in the Gene Expression of Tribolium Castaneum Larvae</i>. Springer Nature, 2017, doi:<a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1\">10.6084/m9.figshare.c.3756974_d5.v1</a>.","chicago":"Greenwood, Jenny, Barbara Milutinovic, Robert Peuß, Sarah Behrens, Daniela Essar, Philip Rosenstiel, Hinrich Schulenburg, and Joachim Kurtz. “Additional File 5: Table S3. of Oral Immune Priming with Bacillus Thuringiensis Induces a Shift in the Gene Expression of Tribolium Castaneum Larvae.” Springer Nature, 2017. <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1\">https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1</a>.","short":"J. Greenwood, B. Milutinovic, R. Peuß, S. Behrens, D. Essar, P. Rosenstiel, H. Schulenburg, J. Kurtz, (2017).","ama":"Greenwood J, Milutinovic B, Peuß R, et al. Additional file 5: Table S3. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae. 2017. doi:<a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1\">10.6084/m9.figshare.c.3756974_d5.v1</a>","apa":"Greenwood, J., Milutinovic, B., Peuß, R., Behrens, S., Essar, D., Rosenstiel, P., … Kurtz, J. (2017). Additional file 5: Table S3. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae. Springer Nature. <a href=\"https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1\">https://doi.org/10.6084/m9.figshare.c.3756974_d5.v1</a>","ieee":"J. Greenwood <i>et al.</i>, “Additional file 5: Table S3. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae.” Springer Nature, 2017."},"article_processing_charge":"No","oa_version":"Published Version","month":"04","date_published":"2017-04-26T00:00:00Z","related_material":{"record":[{"relation":"used_in_publication","id":"1006","status":"public"}]},"doi":"10.6084/m9.figshare.c.3756974_d5.v1","day":"26","department":[{"_id":"SyCr"}],"date_updated":"2025-07-10T11:49:39Z","type":"research_data_reference","date_created":"2021-08-10T08:07:12Z","author":[{"last_name":"Greenwood","full_name":"Greenwood, Jenny","first_name":"Jenny"},{"last_name":"Milutinovic","id":"2CDC32B8-F248-11E8-B48F-1D18A9856A87","full_name":"Milutinovic, Barbara","first_name":"Barbara","orcid":"0000-0002-8214-4758"},{"full_name":"Peuß, Robert","last_name":"Peuß","first_name":"Robert"},{"full_name":"Behrens, Sarah","last_name":"Behrens","first_name":"Sarah"},{"last_name":"Essar","full_name":"Essar, Daniela","first_name":"Daniela"},{"first_name":"Philip","full_name":"Rosenstiel, Philip","last_name":"Rosenstiel"},{"first_name":"Hinrich","last_name":"Schulenburg","full_name":"Schulenburg, Hinrich"},{"last_name":"Kurtz","full_name":"Kurtz, Joachim","first_name":"Joachim"}],"oa":1,"_id":"9860","title":"Additional file 5: Table S3. of Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf"},{"abstract":[{"lang":"eng","text":"As a consequence of its difference in copy number between males and females, the X chromosome is subject to unique evolutionary forces and gene regulatory mechanisms. Previous studies of Drosophila melanogaster have shown that the expression of X-linked, testis-specific reporter genes is suppressed in the male germline. However, it is not known whether this phenomenon is restricted to testis-expressed genes or if it is a more general property of genes with tissue-specific expression, which are also underrepresented on the X chromosome. To test this, we compared the expression of three tissue-specific reporter genes (ovary, accessory gland and Malpighian tubule) inserted at various autosomal and X-chromosomal locations. In contrast to testis-specific reporter genes, we found no reduction of X-linked expression in any of the other tissues. In accessory gland and Malpighian tubule, we detected higher expression of the X-linked reporter genes, which suggests that they are at least partially dosage compensated. We found no difference in the tissue-specificity of X-linked and autosomal reporter genes. These findings indicate that, in general, the X chromosome is not a detrimental environment for tissue-specific gene expression and that the suppression of X-linked expression is limited to the male germline."}],"date_created":"2021-08-10T08:12:52Z","date_updated":"2025-07-10T11:49:45Z","type":"research_data_reference","_id":"9861","title":"Data from: X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","author":[{"last_name":"Argyridou","full_name":"Argyridou, Eliza","first_name":"Eliza"},{"last_name":"Huylmans","id":"4C0A3874-F248-11E8-B48F-1D18A9856A87","full_name":"Huylmans, Ann K","first_name":"Ann K","orcid":"0000-0001-8871-4961"},{"first_name":"Annabella","full_name":"Königer, Annabella","last_name":"Königer"},{"first_name":"John","last_name":"Parsch","full_name":"Parsch, John"}],"oa":1,"publisher":"Dryad","main_file_link":[{"url":"https://doi.org/10.5061/dryad.02f6r","open_access":"1"}],"status":"public","citation":{"apa":"Argyridou, E., Huylmans, A. K., Königer, A., &#38; Parsch, J. (2017). Data from: X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster. Dryad. <a href=\"https://doi.org/10.5061/dryad.02f6r\">https://doi.org/10.5061/dryad.02f6r</a>","ama":"Argyridou E, Huylmans AK, Königer A, Parsch J. Data from: X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster. 2017. doi:<a href=\"https://doi.org/10.5061/dryad.02f6r\">10.5061/dryad.02f6r</a>","ieee":"E. Argyridou, A. K. Huylmans, A. Königer, and J. Parsch, “Data from: X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster.” Dryad, 2017.","ista":"Argyridou E, Huylmans AK, Königer A, Parsch J. 2017. Data from: X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster, Dryad, <a href=\"https://doi.org/10.5061/dryad.02f6r\">10.5061/dryad.02f6r</a>.","mla":"Argyridou, Eliza, et al. <i>Data from: X-Linkage Is Not a General Inhibitor of Tissue-Specific Gene Expression in Drosophila Melanogaster</i>. Dryad, 2017, doi:<a href=\"https://doi.org/10.5061/dryad.02f6r\">10.5061/dryad.02f6r</a>.","chicago":"Argyridou, Eliza, Ann K Huylmans, Annabella Königer, and John Parsch. “Data from: X-Linkage Is Not a General Inhibitor of Tissue-Specific Gene Expression in Drosophila Melanogaster.” Dryad, 2017. <a href=\"https://doi.org/10.5061/dryad.02f6r\">https://doi.org/10.5061/dryad.02f6r</a>.","short":"E. Argyridou, A.K. Huylmans, A. Königer, J. Parsch, (2017)."},"year":"2017","date_published":"2017-02-14T00:00:00Z","month":"02","related_material":{"record":[{"status":"public","id":"1019","relation":"used_in_publication"}]},"doi":"10.5061/dryad.02f6r","day":"14","department":[{"_id":"BeVi"}],"article_processing_charge":"No","oa_version":"Published Version"},{"isi":1,"author":[{"last_name":"Nanda","full_name":"Nanda, Gaurav","first_name":"Gaurav"},{"last_name":"Aguilera Servin","full_name":"Aguilera Servin, Juan L","id":"2A67C376-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2862-8372","first_name":"Juan L"},{"last_name":"Rakyta","full_name":"Rakyta, Péter","first_name":"Péter"},{"first_name":"Andor","last_name":"Kormányos","full_name":"Kormányos, Andor"},{"first_name":"Reinhold","last_name":"Kleiner","full_name":"Kleiner, Reinhold"},{"first_name":"Dieter","full_name":"Koelle, Dieter","last_name":"Koelle"},{"first_name":"Kazuo","last_name":"Watanabe","full_name":"Watanabe, Kazuo"},{"full_name":"Taniguchi, Takashi","last_name":"Taniguchi","first_name":"Takashi"},{"first_name":"Lieven","full_name":"Vandersypen, Lieven","last_name":"Vandersypen"},{"last_name":"Goswami","full_name":"Goswami, Srijit","first_name":"Srijit"}],"_id":"988","external_id":{"isi":["000403631600011"]},"issue":"6","volume":17,"publist_id":"6412","intvolume":"        17","page":"3396 - 3401","article_processing_charge":"No","date_published":"2017-05-05T00:00:00Z","pubrep_id":"826","year":"2017","ddc":["621"],"publisher":"American Chemical Society","oa":1,"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Current-phase relation of ballistic graphene Josephson junctions","date_updated":"2025-07-10T12:02:04Z","type":"journal_article","file_date_updated":"2020-07-14T12:48:18Z","publication_identifier":{"issn":["1530-6984"]},"publication":"Nano Letters","date_created":"2018-12-11T11:49:33Z","abstract":[{"text":"The current-phase relation (CPR) of a Josephson junction (JJ) determines how the supercurrent evolves with the superconducting phase difference across the junction. Knowledge of the CPR is essential in order to understand the response of a JJ to various external parameters. Despite the rising interest in ultraclean encapsulated graphene JJs, the CPR of such junctions remains unknown. Here, we use a fully gate-tunable graphene superconducting quantum intereference device (SQUID) to determine the CPR of ballistic graphene JJs. Each of the two JJs in the SQUID is made with graphene encapsulated in hexagonal boron nitride. By independently controlling the critical current of the JJs, we can operate the SQUID either in a symmetric or asymmetric configuration. The highly asymmetric SQUID allows us to phase-bias one of the JJs and thereby directly obtain its CPR. The CPR is found to be skewed, deviating significantly from a sinusoidal form. The skewness can be tuned with the gate voltage and oscillates in antiphase with Fabry-Pérot resistance oscillations of the ballistic graphene cavity. We compare our experiments with tight-binding calculations that include realistic graphene-superconductor interfaces and find a good qualitative agreement.","lang":"eng"}],"language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Published Version","doi":"10.1021/acs.nanolett.7b00097","day":"05","department":[{"_id":"NanoFab"}],"publication_status":"published","month":"05","scopus_import":"1","file":[{"access_level":"open_access","relation":"main_file","checksum":"22021daa90cf13b01becd776838acb7b","content_type":"application/pdf","file_name":"IST-2017-826-v1+1_2017_Aguilera-Servin_Current.pdf","file_id":"5037","date_created":"2018-12-12T10:13:50Z","file_size":508638,"creator":"system","date_updated":"2020-07-14T12:48:18Z"}],"citation":{"ista":"Nanda G, Aguilera Servin JL, Rakyta P, Kormányos A, Kleiner R, Koelle D, Watanabe K, Taniguchi T, Vandersypen L, Goswami S. 2017. Current-phase relation of ballistic graphene Josephson junctions. Nano Letters. 17(6), 3396–3401.","short":"G. Nanda, J.L. Aguilera Servin, P. Rakyta, A. Kormányos, R. Kleiner, D. Koelle, K. Watanabe, T. Taniguchi, L. Vandersypen, S. Goswami, Nano Letters 17 (2017) 3396–3401.","mla":"Nanda, Gaurav, et al. “Current-Phase Relation of Ballistic Graphene Josephson Junctions.” <i>Nano Letters</i>, vol. 17, no. 6, American Chemical Society, 2017, pp. 3396–401, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.7b00097\">10.1021/acs.nanolett.7b00097</a>.","chicago":"Nanda, Gaurav, Juan L Aguilera Servin, Péter Rakyta, Andor Kormányos, Reinhold Kleiner, Dieter Koelle, Kazuo Watanabe, Takashi Taniguchi, Lieven Vandersypen, and Srijit Goswami. “Current-Phase Relation of Ballistic Graphene Josephson Junctions.” <i>Nano Letters</i>. American Chemical Society, 2017. <a href=\"https://doi.org/10.1021/acs.nanolett.7b00097\">https://doi.org/10.1021/acs.nanolett.7b00097</a>.","apa":"Nanda, G., Aguilera Servin, J. L., Rakyta, P., Kormányos, A., Kleiner, R., Koelle, D., … Goswami, S. (2017). Current-phase relation of ballistic graphene Josephson junctions. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.7b00097\">https://doi.org/10.1021/acs.nanolett.7b00097</a>","ama":"Nanda G, Aguilera Servin JL, Rakyta P, et al. Current-phase relation of ballistic graphene Josephson junctions. <i>Nano Letters</i>. 2017;17(6):3396-3401. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.7b00097\">10.1021/acs.nanolett.7b00097</a>","ieee":"G. Nanda <i>et al.</i>, “Current-phase relation of ballistic graphene Josephson junctions,” <i>Nano Letters</i>, vol. 17, no. 6. American Chemical Society, pp. 3396–3401, 2017."},"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"status":"public"},{"year":"2017","publisher":"Springer","page":"563 - 577","article_processing_charge":"No","date_published":"2017-05-18T00:00:00Z","editor":[{"first_name":"François","full_name":"Lauze, François","last_name":"Lauze"},{"full_name":"Dong, Yiqiu","last_name":"Dong","first_name":"Yiqiu"},{"full_name":"Bjorholm Dahl, Anders","last_name":"Bjorholm Dahl","first_name":"Anders"}],"volume":10302,"publist_id":"6410","intvolume":"     10302","author":[{"id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan","last_name":"Maas","first_name":"Jan","orcid":"0000-0002-0845-1338"},{"last_name":"Rumpf","full_name":"Rumpf, Martin","first_name":"Martin"},{"last_name":"Simon","full_name":"Simon, Stefan","first_name":"Stefan"}],"isi":1,"external_id":{"isi":["000432210900045"]},"_id":"989","alternative_title":["LNCS"],"scopus_import":"1","citation":{"mla":"Maas, Jan, et al. <i>Transport Based Image Morphing with Intensity Modulation</i>. Edited by François Lauze et al., vol. 10302, Springer, 2017, pp. 563–77, doi:<a href=\"https://doi.org/10.1007/978-3-319-58771-4_45\">10.1007/978-3-319-58771-4_45</a>.","short":"J. Maas, M. Rumpf, S. Simon, in:, F. Lauze, Y. Dong, A. Bjorholm Dahl (Eds.), Springer, 2017, pp. 563–577.","chicago":"Maas, Jan, Martin Rumpf, and Stefan Simon. “Transport Based Image Morphing with Intensity Modulation.” edited by François Lauze, Yiqiu Dong, and Anders Bjorholm Dahl, 10302:563–77. Springer, 2017. <a href=\"https://doi.org/10.1007/978-3-319-58771-4_45\">https://doi.org/10.1007/978-3-319-58771-4_45</a>.","ista":"Maas J, Rumpf M, Simon S. 2017. Transport based image morphing with intensity modulation. SSVM:  Scale Space and Variational Methods in Computer Vision, LNCS, vol. 10302, 563–577.","ieee":"J. Maas, M. Rumpf, and S. Simon, “Transport based image morphing with intensity modulation,” presented at the SSVM:  Scale Space and Variational Methods in Computer Vision, Kolding, Denmark, 2017, vol. 10302, pp. 563–577.","ama":"Maas J, Rumpf M, Simon S. Transport based image morphing with intensity modulation. In: Lauze F, Dong Y, Bjorholm Dahl A, eds. Vol 10302. Springer; 2017:563-577. doi:<a href=\"https://doi.org/10.1007/978-3-319-58771-4_45\">10.1007/978-3-319-58771-4_45</a>","apa":"Maas, J., Rumpf, M., &#38; Simon, S. (2017). Transport based image morphing with intensity modulation. In F. Lauze, Y. Dong, &#38; A. Bjorholm Dahl (Eds.) (Vol. 10302, pp. 563–577). Presented at the SSVM:  Scale Space and Variational Methods in Computer Vision, Kolding, Denmark: Springer. <a href=\"https://doi.org/10.1007/978-3-319-58771-4_45\">https://doi.org/10.1007/978-3-319-58771-4_45</a>"},"status":"public","quality_controlled":"1","oa_version":"None","language":[{"iso":"eng"}],"doi":"10.1007/978-3-319-58771-4_45","day":"18","publication_status":"published","department":[{"_id":"JaMa"}],"month":"05","date_updated":"2026-04-16T10:05:10Z","type":"conference","publication_identifier":{"issn":["0302-9743"]},"date_created":"2018-12-11T11:49:34Z","abstract":[{"lang":"eng","text":"We present a generalized optimal transport model in which the mass-preserving constraint for the L2-Wasserstein distance is relaxed by introducing a source term in the continuity equation. The source term is also incorporated in the path energy by means of its squared L2-norm in time of a functional with linear growth in space. This extension of the original transport model enables local density modulations, which is a desirable feature in applications such as image warping and blending. A key advantage of the use of a functional with linear growth in space is that it allows for singular sources and sinks, which can be supported on points or lines. On a technical level, the L2-norm in time ensures a disintegration of the source in time, which we use to obtain the well-posedness of the model and the existence of geodesic paths. The numerical discretization is based on the proximal splitting approach [18] and selected numerical test cases show the potential of the proposed approach. Furthermore, the approach is applied to the warping and blending of textures."}],"conference":{"name":"SSVM:  Scale Space and Variational Methods in Computer Vision","start_date":"2017-06-04","location":"Kolding, Denmark","end_date":"2017-06-08"},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Transport based image morphing with intensity modulation"},{"pmid":1,"date_published":"2017-06-01T00:00:00Z","page":"1478 - 1493 ","article_processing_charge":"No","ddc":["576"],"publisher":"Wiley-Blackwell","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme"},{"_id":"25B07788-B435-11E9-9278-68D0E5697425","grant_number":"250152","name":"Limits to selection in biology and in evolutionary computation","call_identifier":"FP7"}],"pubrep_id":"977","year":"2017","external_id":{"isi":["000403014800005"],"pmid":["28419447"]},"_id":"990","issue":"6","author":[{"id":"42377A0A-F248-11E8-B48F-1D18A9856A87","full_name":"Sachdeva, Himani","last_name":"Sachdeva","first_name":"Himani"},{"orcid":"0000-0002-8548-5240","first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"}],"isi":1,"publist_id":"6409","intvolume":"        71","volume":71,"doi":"10.1111/evo.13252","day":"01","ec_funded":1,"publication_status":"published","department":[{"_id":"NiBa"}],"corr_author":"1","month":"06","language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Submitted Version","citation":{"ista":"Sachdeva H, Barton NH. 2017. Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow. Evolution; International Journal of Organic Evolution. 71(6), 1478–1493.","mla":"Sachdeva, Himani, and Nicholas H. Barton. “Divergence and Evolution of Assortative Mating in a Polygenic Trait Model of Speciation with Gene Flow.” <i>Evolution; International Journal of Organic Evolution</i>, vol. 71, no. 6, Wiley-Blackwell, 2017, pp. 1478–93, doi:<a href=\"https://doi.org/10.1111/evo.13252\">10.1111/evo.13252</a>.","short":"H. Sachdeva, N.H. Barton, Evolution; International Journal of Organic Evolution 71 (2017) 1478–1493.","chicago":"Sachdeva, Himani, and Nicholas H Barton. “Divergence and Evolution of Assortative Mating in a Polygenic Trait Model of Speciation with Gene Flow.” <i>Evolution; International Journal of Organic Evolution</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1111/evo.13252\">https://doi.org/10.1111/evo.13252</a>.","ama":"Sachdeva H, Barton NH. Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow. <i>Evolution; International Journal of Organic Evolution</i>. 2017;71(6):1478-1493. doi:<a href=\"https://doi.org/10.1111/evo.13252\">10.1111/evo.13252</a>","apa":"Sachdeva, H., &#38; Barton, N. H. (2017). Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow. <i>Evolution; International Journal of Organic Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/evo.13252\">https://doi.org/10.1111/evo.13252</a>","ieee":"H. Sachdeva and N. H. Barton, “Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow,” <i>Evolution; International Journal of Organic Evolution</i>, vol. 71, no. 6. Wiley-Blackwell, pp. 1478–1493, 2017."},"file":[{"relation":"main_file","checksum":"6d4c38cb1347fd43620d1736c6df5c79","content_type":"application/pdf","access_level":"open_access","file_size":625260,"creator":"dernst","date_updated":"2020-07-14T12:48:18Z","file_name":"2017_Evolution_Sachdeva_supplement.pdf","file_id":"6329","date_created":"2019-04-17T07:37:04Z"},{"access_level":"open_access","relation":"main_file","checksum":"f1d90dd8831b44baf49b4dd176f263af","content_type":"application/pdf","file_name":"2017_Evolution_Sachdeva_article.pdf","date_created":"2019-04-17T07:37:04Z","file_id":"6330","file_size":520110,"creator":"dernst","date_updated":"2020-07-14T12:48:18Z"}],"status":"public","scopus_import":"1","title":"Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","oa":1,"publication_identifier":{"issn":["0014-3820"]},"publication":"Evolution; International Journal of Organic Evolution","date_created":"2018-12-11T11:49:34Z","abstract":[{"text":"Assortative mating is an important driver of speciation in populations with gene flow and is predicted to evolve under certain conditions in few-locus models. However, the evolution of assortment is less understood for mating based on quantitative traits, which are often characterized by high genetic variability and extensive linkage disequilibrium between trait loci. We explore this scenario for a two-deme model with migration, by considering a single polygenic trait subject to divergent viability selection across demes, as well as assortative mating and sexual selection within demes, and investigate how trait divergence is shaped by various evolutionary forces. Our analysis reveals the existence of sharp thresholds of assortment strength, at which divergence increases dramatically. We also study the evolution of assortment via invasion of modifiers of mate discrimination and show that the ES assortment strength has an intermediate value under a range of migration-selection parameters, even in diverged populations, due to subtle effects which depend sensitively on the extent of phenotypic variation within these populations. The evolutionary dynamics of the polygenic trait is studied using the hypergeometric and infinitesimal models. We further investigate the sensitivity of our results to the assumptions of the hypergeometric model, using individual-based simulations.","lang":"eng"}],"date_updated":"2025-07-10T12:02:04Z","type":"journal_article","file_date_updated":"2020-07-14T12:48:18Z"},{"type":"journal_article","date_updated":"2026-04-16T10:05:51Z","abstract":[{"text":"Synaptotagmin 7 (Syt7) was originally identified as a slow Ca2+ sensor for lysosome fusion, but its function at fast synapses is controversial. The paper by Luo and Südhof (2017) in this issue of Neuron shows that at the calyx of Held in the auditory brainstem Syt7 triggers asynchronous release during stimulus trains, resulting in reliable and temporally precise high-frequency transmission. Thus, a slow Ca2+ sensor contributes to the fast signaling properties of the calyx synapse.","lang":"eng"}],"date_created":"2018-12-11T11:49:34Z","publication":"Neuron","publication_identifier":{"issn":["0896-6273"]},"title":"Synaptotagmins: That’s why so many","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","scopus_import":"1","status":"public","citation":{"short":"C. Chen, P.M. Jonas, Neuron 94 (2017) 694–696.","mla":"Chen, Chong, and Peter M. Jonas. “Synaptotagmins: That’s Why so Many.” <i>Neuron</i>, vol. 94, no. 4, Elsevier, 2017, pp. 694–96, doi:<a href=\"https://doi.org/10.1016/j.neuron.2017.05.011\">10.1016/j.neuron.2017.05.011</a>.","chicago":"Chen, Chong, and Peter M Jonas. “Synaptotagmins: That’s Why so Many.” <i>Neuron</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.neuron.2017.05.011\">https://doi.org/10.1016/j.neuron.2017.05.011</a>.","ista":"Chen C, Jonas PM. 2017. Synaptotagmins: That’s why so many. Neuron. 94(4), 694–696.","ieee":"C. Chen and P. M. Jonas, “Synaptotagmins: That’s why so many,” <i>Neuron</i>, vol. 94, no. 4. Elsevier, pp. 694–696, 2017.","ama":"Chen C, Jonas PM. Synaptotagmins: That’s why so many. <i>Neuron</i>. 2017;94(4):694-696. doi:<a href=\"https://doi.org/10.1016/j.neuron.2017.05.011\">10.1016/j.neuron.2017.05.011</a>","apa":"Chen, C., &#38; Jonas, P. M. (2017). Synaptotagmins: That’s why so many. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2017.05.011\">https://doi.org/10.1016/j.neuron.2017.05.011</a>"},"language":[{"iso":"eng"}],"oa_version":"None","quality_controlled":"1","month":"05","department":[{"_id":"PeJo"}],"publication_status":"published","doi":"10.1016/j.neuron.2017.05.011","day":"17","volume":94,"intvolume":"        94","publist_id":"6408","author":[{"id":"3DFD581A-F248-11E8-B48F-1D18A9856A87","full_name":"Chen, Chong","last_name":"Chen","first_name":"Chong"},{"first_name":"Peter M","orcid":"0000-0001-5001-4804","last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","full_name":"Jonas, Peter M"}],"isi":1,"external_id":{"isi":["000401415100002"]},"_id":"991","issue":"4","year":"2017","publisher":"Elsevier","article_processing_charge":"No","page":"694 - 696","date_published":"2017-05-17T00:00:00Z"},{"publisher":"Institute of Science and Technology Austria","project":[{"name":"Discrete Optimization in Computer Vision: Theory and Practice","call_identifier":"FP7","grant_number":"616160","_id":"25FBA906-B435-11E9-9278-68D0E5697425"}],"ddc":["004"],"pubrep_id":"815","degree_awarded":"PhD","year":"2017","date_published":"2017-05-01T00:00:00Z","article_processing_charge":"No","page":"97","publist_id":"6407","_id":"992","alternative_title":["ISTA Thesis"],"author":[{"first_name":"Michal","full_name":"Rolinek, Michal","id":"3CB3BC06-F248-11E8-B48F-1D18A9856A87","last_name":"Rolinek"}],"status":"public","citation":{"ista":"Rolinek M. 2017. Complexity of constraint satisfaction. Institute of Science and Technology Austria.","mla":"Rolinek, Michal. <i>Complexity of Constraint Satisfaction</i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_815\">10.15479/AT:ISTA:th_815</a>.","chicago":"Rolinek, Michal. “Complexity of Constraint Satisfaction.” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:th_815\">https://doi.org/10.15479/AT:ISTA:th_815</a>.","short":"M. Rolinek, Complexity of Constraint Satisfaction, Institute of Science and Technology Austria, 2017.","apa":"Rolinek, M. (2017). <i>Complexity of constraint satisfaction</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_815\">https://doi.org/10.15479/AT:ISTA:th_815</a>","ama":"Rolinek M. Complexity of constraint satisfaction. 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_815\">10.15479/AT:ISTA:th_815</a>","ieee":"M. Rolinek, “Complexity of constraint satisfaction,” Institute of Science and Technology Austria, 2017."},"file":[{"access_level":"open_access","content_type":"application/pdf","checksum":"81761fb939acb7585c36629f765b4373","relation":"main_file","file_id":"4654","date_created":"2018-12-12T10:07:55Z","file_name":"IST-2017-815-v1+3_final_blank_signature_maybe_pdfa.pdf","date_updated":"2020-07-14T12:48:18Z","creator":"system","file_size":786145},{"file_id":"6208","date_created":"2019-04-05T08:43:24Z","file_name":"2017_Thesis_Rolinek_source.zip","date_updated":"2020-07-14T12:48:18Z","file_size":5936337,"creator":"dernst","access_level":"closed","content_type":"application/zip","relation":"source_file","checksum":"2b2d7e1d6c1c79a9795a7aa0f860baf3"}],"acknowledgement":"FP7/2007-2013/ERC grant agreement no 616160","corr_author":"1","month":"05","ec_funded":1,"day":"01","doi":"10.15479/AT:ISTA:th_815","publication_status":"published","department":[{"_id":"VlKo"}],"oa_version":"Published Version","language":[{"iso":"eng"}],"abstract":[{"text":"An instance of the Constraint Satisfaction Problem (CSP) is given by a finite set of\r\nvariables, a finite domain of labels, and a set of constraints, each constraint acting on\r\na subset of the variables. The goal is to find an assignment of labels to its variables\r\nthat satisfies all constraints (or decide whether one exists). If we allow more general\r\n“soft” constraints, which come with (possibly infinite) costs of particular assignments,\r\nwe obtain instances from a richer class called Valued Constraint Satisfaction Problem\r\n(VCSP). There the goal is to find an assignment with minimum total cost.\r\nIn this thesis, we focus (assuming that P\r\n6\r\n=\r\nNP) on classifying computational com-\r\nplexity of CSPs and VCSPs under certain restricting conditions. Two results are the core\r\ncontent of the work. In one of them, we consider VCSPs parametrized by a constraint\r\nlanguage, that is the set of “soft” constraints allowed to form the instances, and finish\r\nthe complexity classification modulo (missing pieces of) complexity classification for\r\nanalogously parametrized CSP. The other result is a generalization of Edmonds’ perfect\r\nmatching algorithm. This generalization contributes to complexity classfications in two\r\nways. First, it gives a new (largest known) polynomial-time solvable class of Boolean\r\nCSPs in which every variable may appear in at most two constraints and second, it\r\nsettles full classification of Boolean CSPs with planar drawing (again parametrized by a\r\nconstraint language).","lang":"eng"}],"publication_identifier":{"issn":["2663-337X"]},"supervisor":[{"last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir"}],"date_created":"2018-12-11T11:49:35Z","file_date_updated":"2020-07-14T12:48:18Z","date_updated":"2026-04-08T14:17:06Z","type":"dissertation","OA_place":"publisher","title":"Complexity of constraint satisfaction","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","has_accepted_license":"1","oa":1},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Subsampling scaling","oa":1,"has_accepted_license":"1","abstract":[{"text":"In real-world applications, observations are often constrained to a small fraction of a system. Such spatial subsampling can be caused by the inaccessibility or the sheer size of the system, and cannot be overcome by longer sampling. Spatial subsampling can strongly bias inferences about a system’s aggregated properties. To overcome the bias, we derive analytically a subsampling scaling framework that is applicable to different observables, including distributions of neuronal avalanches, of number of people infected during an epidemic outbreak, and of node degrees. We demonstrate how to infer the correct distributions of the underlying full system, how to apply it to distinguish critical from subcritical systems, and how to disentangle subsampling and finite size effects. Lastly, we apply subsampling scaling to neuronal avalanche models and to recordings from developing neural networks. We show that only mature, but not young networks follow power-law scaling, indicating self-organization to criticality during development.","lang":"eng"}],"publication_identifier":{"issn":["2041-1723"]},"date_created":"2018-12-11T11:49:35Z","publication":"Nature Communications","file_date_updated":"2020-07-14T12:48:19Z","date_updated":"2025-07-10T12:02:06Z","type":"journal_article","month":"05","day":"04","ec_funded":1,"doi":"10.1038/ncomms15140","department":[{"_id":"GaTk"},{"_id":"JoCs"}],"publication_status":"published","oa_version":"Published Version","language":[{"iso":"eng"}],"quality_controlled":"1","status":"public","file":[{"access_level":"open_access","checksum":"9880212f8c4c53404c7c6fbf9023c53a","relation":"main_file","content_type":"application/pdf","file_name":"IST-2017-819-v1+1_2017_Levina_SubsamplingScaling.pdf","date_created":"2018-12-12T10:15:05Z","file_id":"5122","creator":"system","file_size":746224,"date_updated":"2020-07-14T12:48:19Z"}],"citation":{"ieee":"A. Levina (Martius) and V. Priesemann, “Subsampling scaling,” <i>Nature Communications</i>, vol. 8. Nature Publishing Group, 2017.","ama":"Levina (Martius) A, Priesemann V. Subsampling scaling. <i>Nature Communications</i>. 2017;8. doi:<a href=\"https://doi.org/10.1038/ncomms15140\">10.1038/ncomms15140</a>","apa":"Levina (Martius), A., &#38; Priesemann, V. (2017). Subsampling scaling. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncomms15140\">https://doi.org/10.1038/ncomms15140</a>","mla":"Levina (Martius), Anna, and Viola Priesemann. “Subsampling Scaling.” <i>Nature Communications</i>, vol. 8, 15140, Nature Publishing Group, 2017, doi:<a href=\"https://doi.org/10.1038/ncomms15140\">10.1038/ncomms15140</a>.","chicago":"Levina (Martius), Anna, and Viola Priesemann. “Subsampling Scaling.” <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/ncomms15140\">https://doi.org/10.1038/ncomms15140</a>.","short":"A. Levina (Martius), V. Priesemann, Nature Communications 8 (2017).","ista":"Levina (Martius) A, Priesemann V. 2017. Subsampling scaling. Nature Communications. 8, 15140."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"scopus_import":"1","_id":"993","external_id":{"isi":["000400560700001"]},"author":[{"last_name":"Levina (Martius)","id":"35AF8020-F248-11E8-B48F-1D18A9856A87","full_name":"Levina (Martius), Anna","first_name":"Anna"},{"full_name":"Priesemann, Viola","last_name":"Priesemann","first_name":"Viola"}],"isi":1,"intvolume":"         8","publist_id":"6406","volume":8,"date_published":"2017-05-04T00:00:00Z","article_processing_charge":"Yes (in subscription journal)","publisher":"Nature Publishing Group","project":[{"grant_number":"291734","name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"ddc":["005","571"],"article_number":"15140","pubrep_id":"819","year":"2017"},{"date_published":"2017-08-08T00:00:00Z","article_processing_charge":"No","project":[{"grant_number":"P29902","call_identifier":"FWF","name":"Quantum rotations in the presence of a many-body environment","_id":"26031614-B435-11E9-9278-68D0E5697425"},{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","name":"International IST Doctoral Program","call_identifier":"H2020"}],"publisher":"American Physical Society","year":"2017","_id":"994","external_id":{"isi":["000416564000004"],"arxiv":["1705.09220"]},"issue":"3","author":[{"last_name":"Cherepanov","full_name":"Cherepanov, Igor","id":"339C7E5A-F248-11E8-B48F-1D18A9856A87","first_name":"Igor"},{"orcid":"0000-0002-6990-7802","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko"}],"isi":1,"intvolume":"         1","publist_id":"6405","volume":1,"month":"08","corr_author":"1","publication_status":"published","department":[{"_id":"MiLe"}],"day":"08","ec_funded":1,"doi":"10.1103/PhysRevMaterials.1.035602","arxiv":1,"quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Submitted Version","status":"public","main_file_link":[{"url":"https://arxiv.org/abs/1705.09220","open_access":"1"}],"citation":{"ieee":"I. Cherepanov and M. Lemeshko, “Fingerprints of angulon instabilities in the spectra of matrix-isolated molecules,” <i>Physical Review Materials</i>, vol. 1, no. 3. American Physical Society, 2017.","apa":"Cherepanov, I., &#38; Lemeshko, M. (2017). Fingerprints of angulon instabilities in the spectra of matrix-isolated molecules. <i>Physical Review Materials</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevMaterials.1.035602\">https://doi.org/10.1103/PhysRevMaterials.1.035602</a>","ama":"Cherepanov I, Lemeshko M. Fingerprints of angulon instabilities in the spectra of matrix-isolated molecules. <i>Physical Review Materials</i>. 2017;1(3). doi:<a href=\"https://doi.org/10.1103/PhysRevMaterials.1.035602\">10.1103/PhysRevMaterials.1.035602</a>","mla":"Cherepanov, Igor, and Mikhail Lemeshko. “Fingerprints of Angulon Instabilities in the Spectra of Matrix-Isolated Molecules.” <i>Physical Review Materials</i>, vol. 1, no. 3, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevMaterials.1.035602\">10.1103/PhysRevMaterials.1.035602</a>.","chicago":"Cherepanov, Igor, and Mikhail Lemeshko. “Fingerprints of Angulon Instabilities in the Spectra of Matrix-Isolated Molecules.” <i>Physical Review Materials</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevMaterials.1.035602\">https://doi.org/10.1103/PhysRevMaterials.1.035602</a>.","short":"I. Cherepanov, M. Lemeshko, Physical Review Materials 1 (2017).","ista":"Cherepanov I, Lemeshko M. 2017. Fingerprints of angulon instabilities in the spectra of matrix-isolated molecules. Physical Review Materials. 1(3)."},"scopus_import":"1","title":"Fingerprints of angulon instabilities in the spectra of matrix-isolated molecules","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"abstract":[{"lang":"eng","text":"The formation of vortices is usually considered to be the main mechanism of angular momentum disposal in superfluids. Recently, it was predicted that a superfluid can acquire angular momentum via an alternative, microscopic route -- namely, through interaction with rotating impurities, forming so-called `angulon quasiparticles' [Phys. Rev. Lett. 114, 203001 (2015)]. The angulon instabilities correspond to transfer of a small number of angular momentum quanta from the impurity to the superfluid, as opposed to vortex instabilities, where angular momentum is quantized in units of ℏ  per atom. Furthermore, since conventional impurities (such as molecules) represent three-dimensional (3D) rotors, the angular momentum transferred is intrinsically 3D as well, as opposed to a merely planar rotation which is inherent to vortices. Herein we show that the angulon theory can explain the anomalous broadening of the spectroscopic lines observed for CH 3   and NH 3   molecules in superfluid helium nanodroplets, thereby providing a fingerprint of the emerging angulon instabilities in experiment."}],"publication":"Physical Review Materials","date_created":"2018-12-11T11:49:35Z","type":"journal_article","date_updated":"2025-06-04T10:15:04Z"},{"arxiv":1,"language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Submitted Version","corr_author":"1","month":"08","day":"07","doi":"10.1103/PhysRevB.96.085410","department":[{"_id":"MiLe"}],"publication_status":"published","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1704.02616"}],"status":"public","citation":{"chicago":"Bighin, Giacomo, and Mikhail Lemeshko. “Diagrammatic Approach to Orbital Quantum Impurities Interacting with a Many-Particle Environment.” <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">https://doi.org/10.1103/PhysRevB.96.085410</a>.","short":"G. Bighin, M. Lemeshko, Physical Review B - Condensed Matter and Materials Physics 96 (2017).","mla":"Bighin, Giacomo, and Mikhail Lemeshko. “Diagrammatic Approach to Orbital Quantum Impurities Interacting with a Many-Particle Environment.” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 96, no. 8, 085410, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">10.1103/PhysRevB.96.085410</a>.","ista":"Bighin G, Lemeshko M. 2017. Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. Physical Review B - Condensed Matter and Materials Physics. 96(8), 085410.","ieee":"G. Bighin and M. Lemeshko, “Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment,” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 96, no. 8. American Physical Society, 2017.","apa":"Bighin, G., &#38; Lemeshko, M. (2017). Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">https://doi.org/10.1103/PhysRevB.96.085410</a>","ama":"Bighin G, Lemeshko M. Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. <i>Physical Review B - Condensed Matter and Materials Physics</i>. 2017;96(8). doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">10.1103/PhysRevB.96.085410</a>"},"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment","date_updated":"2025-06-04T08:17:18Z","type":"journal_article","abstract":[{"text":"Recently it was shown that an impurity exchanging orbital angular momentum with a surrounding bath can be described in terms of the angulon quasiparticle [Phys. Rev. Lett. 118, 095301 (2017)]. The angulon consists of a quantum rotor dressed by a many-particle field of boson excitations, and can be formed out of, for example, a molecule or a nonspherical atom in superfluid helium, or out of an electron coupled to lattice phonons or a Bose condensate. Here we develop an approach to the angulon based on the path-integral formalism, which sets the ground for a systematic, perturbative treatment of the angulon problem. The resulting perturbation series can be interpreted in terms of Feynman diagrams, from which, in turn, one can derive a set of diagrammatic rules. These rules extend the machinery of the graphical theory of angular momentum - well known from theoretical atomic spectroscopy - to the case where an environment with an infinite number of degrees of freedom is present. In particular, we show that each diagram can be interpreted as a 'skeleton', which enforces angular momentum conservation, dressed by an additional many-body contribution. This connection between the angulon theory and the graphical theory of angular momentum is particularly important as it allows to systematically and substantially simplify the analytical representation of each diagram. In order to exemplify the technique, we calculate the 1- and 2-loop contributions to the angulon self-energy, the spectral function, and the quasiparticle weight. The diagrammatic theory we develop paves the way to investigate next-to-leading order quantities in a more compact way compared to the variational approaches.","lang":"eng"}],"publication_identifier":{"issn":["2469-9950"]},"date_created":"2018-12-11T11:49:36Z","publication":"Physical Review B - Condensed Matter and Materials Physics","article_processing_charge":"No","date_published":"2017-08-07T00:00:00Z","article_number":"085410","year":"2017","publisher":"American Physical Society","project":[{"call_identifier":"FWF","name":"Quantum rotations in the presence of a many-body environment","grant_number":"P29902","_id":"26031614-B435-11E9-9278-68D0E5697425"}],"author":[{"orcid":"0000-0001-8823-9777","first_name":"Giacomo","last_name":"Bighin","full_name":"Bighin, Giacomo","id":"4CA96FD4-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Lemeshko","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","first_name":"Mikhail"}],"isi":1,"_id":"995","issue":"8","external_id":{"isi":["000407017100009"],"arxiv":["1704.02616"]},"volume":96,"intvolume":"        96","publist_id":"6404"},{"volume":147,"publist_id":"6403","intvolume":"       147","author":[{"first_name":"Benjamin","full_name":"Shepperson, Benjamin","last_name":"Shepperson"},{"first_name":"Adam","full_name":"Chatterley, Adam","last_name":"Chatterley"},{"first_name":"Anders","full_name":"Søndergaard, Anders","last_name":"Søndergaard"},{"first_name":"Lars","full_name":"Christiansen, Lars","last_name":"Christiansen"},{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","last_name":"Lemeshko","first_name":"Mikhail","orcid":"0000-0002-6990-7802"},{"first_name":"Henrik","full_name":"Stapelfeldt, Henrik","last_name":"Stapelfeldt"}],"isi":1,"_id":"996","issue":"1","external_id":{"arxiv":["1704.03684"],"isi":["000405089400047"]},"year":"2017","article_number":"013946","publisher":"AIP Publishing","article_processing_charge":"No","date_published":"2017-06-01T00:00:00Z","type":"journal_article","date_updated":"2025-06-04T08:17:46Z","publication":"The Journal of Chemical Physics","date_created":"2018-12-11T11:49:36Z","publication_identifier":{"issn":["0021-9606"]},"abstract":[{"lang":"eng","text":"Iodine (I 2  ) molecules embedded in He nanodroplets are aligned by a 160 ps long laser pulse. The highest degree of alignment, occurring at the peak of the pulse and quantified by ⟨cos 2 θ 2D ⟩ , is measured as a function of the laser intensity. The results are well described by ⟨cos 2 θ 2D ⟩  calculated for a gas of isolated molecules each with an effective rotational constant of 0.6 times the gas-phase value, and at a temperature of 0.4 K. Theoretical analysis using the angulon quasiparticle to describe rotating molecules in superfluid helium rationalizes why the alignment mechanism is similar to that of isolated molecules with an effective rotational constant. A major advantage of molecules in He droplets is that their 0.4 K temperature leads to stronger alignment than what can generally be achieved for gas phase molecules -- here demonstrated by a direct comparison of the droplet results to measurements on a ∼  1 K supersonic beam of isolated molecules. This point is further illustrated for more complex system by measurements on 1,4-diiodobenzene and 1,4-dibromobenzene. For all three molecular species studied the highest values of ⟨cos 2 θ 2D ⟩  achieved in He droplets exceed 0.96. "}],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Strongly aligned molecules inside helium droplets in the near-adiabatic regime","scopus_import":"1","citation":{"ieee":"B. Shepperson, A. Chatterley, A. Søndergaard, L. Christiansen, M. Lemeshko, and H. Stapelfeldt, “Strongly aligned molecules inside helium droplets in the near-adiabatic regime,” <i>The Journal of Chemical Physics</i>, vol. 147, no. 1. AIP Publishing, 2017.","apa":"Shepperson, B., Chatterley, A., Søndergaard, A., Christiansen, L., Lemeshko, M., &#38; Stapelfeldt, H. (2017). Strongly aligned molecules inside helium droplets in the near-adiabatic regime. <i>The Journal of Chemical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/1.4983703\">https://doi.org/10.1063/1.4983703</a>","ama":"Shepperson B, Chatterley A, Søndergaard A, Christiansen L, Lemeshko M, Stapelfeldt H. Strongly aligned molecules inside helium droplets in the near-adiabatic regime. <i>The Journal of Chemical Physics</i>. 2017;147(1). doi:<a href=\"https://doi.org/10.1063/1.4983703\">10.1063/1.4983703</a>","mla":"Shepperson, Benjamin, et al. “Strongly Aligned Molecules inside Helium Droplets in the Near-Adiabatic Regime.” <i>The Journal of Chemical Physics</i>, vol. 147, no. 1, 013946, AIP Publishing, 2017, doi:<a href=\"https://doi.org/10.1063/1.4983703\">10.1063/1.4983703</a>.","chicago":"Shepperson, Benjamin, Adam Chatterley, Anders Søndergaard, Lars Christiansen, Mikhail Lemeshko, and Henrik Stapelfeldt. “Strongly Aligned Molecules inside Helium Droplets in the Near-Adiabatic Regime.” <i>The Journal of Chemical Physics</i>. AIP Publishing, 2017. <a href=\"https://doi.org/10.1063/1.4983703\">https://doi.org/10.1063/1.4983703</a>.","short":"B. Shepperson, A. Chatterley, A. Søndergaard, L. Christiansen, M. Lemeshko, H. Stapelfeldt, The Journal of Chemical Physics 147 (2017).","ista":"Shepperson B, Chatterley A, Søndergaard A, Christiansen L, Lemeshko M, Stapelfeldt H. 2017. Strongly aligned molecules inside helium droplets in the near-adiabatic regime. The Journal of Chemical Physics. 147(1), 013946."},"main_file_link":[{"url":"https://arxiv.org/abs/1704.03684","open_access":"1"}],"status":"public","oa_version":"Submitted Version","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"department":[{"_id":"MiLe"}],"publication_status":"published","day":"01","doi":"10.1063/1.4983703","month":"06"},{"date_updated":"2025-04-14T07:26:54Z","type":"journal_article","publication_identifier":{"issn":["0031-9007"]},"publication":"Physical Review Letters","date_created":"2018-12-11T11:49:36Z","abstract":[{"text":"Recently it was shown that molecules rotating in superfluid helium can be described in terms of the angulon quasiparticles (Phys. Rev. Lett. 118, 095301 (2017)). Here we demonstrate that in the experimentally realized regime the angulon can be seen as a point charge on a 2-sphere interacting with a gauge field of a non-abelian magnetic monopole. Unlike in several other settings, the gauge fields of the angulon problem emerge in the real coordinate space, as opposed to the momentum space or some effective parameter space. Furthermore, we find a topological transition associated with making the monopole abelian, which takes place in the vicinity of the previously reported angulon instabilities. These results pave the way for studying topological phenomena in experiments on molecules trapped in superfluid helium nanodroplets, as well as on other realizations of orbital impurity problems.","lang":"eng"}],"oa":1,"title":"Emergence of non-abelian magnetic monopoles in a quantum impurity problem","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","scopus_import":"1","citation":{"chicago":"Yakaboylu, Enderalp, Andreas Deuchert, and Mikhail Lemeshko. “Emergence of Non-Abelian Magnetic Monopoles in a Quantum Impurity Problem.” <i>Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">https://doi.org/10.1103/PhysRevLett.119.235301</a>.","short":"E. Yakaboylu, A. Deuchert, M. Lemeshko, Physical Review Letters 119 (2017).","mla":"Yakaboylu, Enderalp, et al. “Emergence of Non-Abelian Magnetic Monopoles in a Quantum Impurity Problem.” <i>Physical Review Letters</i>, vol. 119, no. 23, 235301, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">10.1103/PhysRevLett.119.235301</a>.","ista":"Yakaboylu E, Deuchert A, Lemeshko M. 2017. Emergence of non-abelian magnetic monopoles in a quantum impurity problem. Physical Review Letters. 119(23), 235301.","ieee":"E. Yakaboylu, A. Deuchert, and M. Lemeshko, “Emergence of non-abelian magnetic monopoles in a quantum impurity problem,” <i>Physical Review Letters</i>, vol. 119, no. 23. American Physical Society, 2017.","ama":"Yakaboylu E, Deuchert A, Lemeshko M. Emergence of non-abelian magnetic monopoles in a quantum impurity problem. <i>Physical Review Letters</i>. 2017;119(23). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">10.1103/PhysRevLett.119.235301</a>","apa":"Yakaboylu, E., Deuchert, A., &#38; Lemeshko, M. (2017). Emergence of non-abelian magnetic monopoles in a quantum impurity problem. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">https://doi.org/10.1103/PhysRevLett.119.235301</a>"},"main_file_link":[{"url":"https://arxiv.org/abs/1705.05162","open_access":"1"}],"status":"public","quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Preprint","arxiv":1,"day":"06","ec_funded":1,"doi":"10.1103/PhysRevLett.119.235301","department":[{"_id":"MiLe"},{"_id":"RoSe"}],"publication_status":"published","month":"12","corr_author":"1","volume":119,"publist_id":"6401","intvolume":"       119","isi":1,"author":[{"id":"38CB71F6-F248-11E8-B48F-1D18A9856A87","full_name":"Yakaboylu, Enderalp","last_name":"Yakaboylu","first_name":"Enderalp","orcid":"0000-0001-5973-0874"},{"id":"4DA65CD0-F248-11E8-B48F-1D18A9856A87","full_name":"Deuchert, Andreas","last_name":"Deuchert","first_name":"Andreas","orcid":"0000-0003-3146-6746"},{"last_name":"Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","first_name":"Mikhail","orcid":"0000-0002-6990-7802"}],"issue":"23","_id":"997","external_id":{"arxiv":["1705.05162"],"isi":["000417132100007"]},"article_number":"235301","year":"2017","publisher":"American Physical Society","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme"},{"_id":"25C6DC12-B435-11E9-9278-68D0E5697425","grant_number":"694227","name":"Analysis of quantum many-body systems","call_identifier":"H2020"},{"_id":"26031614-B435-11E9-9278-68D0E5697425","grant_number":"P29902","name":"Quantum rotations in the presence of a many-body environment","call_identifier":"FWF"}],"article_processing_charge":"No","date_published":"2017-12-06T00:00:00Z"},{"external_id":{"isi":["000418371405066"],"arxiv":["1611.07725"]},"_id":"998","isi":1,"author":[{"first_name":"Sylvestre Alvise","full_name":"Rebuffi, Sylvestre Alvise","last_name":"Rebuffi"},{"last_name":"Kolesnikov","full_name":"Kolesnikov, Alexander","id":"2D157DB6-F248-11E8-B48F-1D18A9856A87","first_name":"Alexander"},{"last_name":"Sperl","id":"4DD40360-F248-11E8-B48F-1D18A9856A87","full_name":"Sperl, Georg","first_name":"Georg"},{"last_name":"Lampert","full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8622-7887","first_name":"Christoph"}],"publist_id":"6400","intvolume":"      2017","volume":2017,"date_published":"2017-04-14T00:00:00Z","page":"5533 - 5542","article_processing_charge":"No","project":[{"_id":"2532554C-B435-11E9-9278-68D0E5697425","name":"Lifelong Learning of Visual Scene Understanding","call_identifier":"FP7","grant_number":"308036"}],"publisher":"IEEE","year":"2017","title":"iCaRL: Incremental classifier and representation learning","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"conference":{"end_date":"2017-07-26","location":"Honolulu, HA, United States","start_date":"2017-07-21","name":"CVPR: Computer Vision and Pattern Recognition"},"date_created":"2018-12-11T11:49:37Z","publication_identifier":{"isbn":["978-153860457-1"]},"abstract":[{"lang":"eng","text":"A major open problem on the road to artificial intelligence is the development of incrementally learning systems that learn about more and more concepts over time from a stream of data. In this work, we introduce a new training strategy, iCaRL, that allows learning in such a class-incremental way: only the training data for a small number of classes has to be present at the same time and new classes can be added progressively. iCaRL learns strong classifiers and a data representation simultaneously. This distinguishes it from earlier works that were fundamentally limited to fixed data representations and therefore incompatible with deep learning architectures. We show by experiments on CIFAR-100 and ImageNet ILSVRC 2012 data that iCaRL can learn many classes incrementally over a long period of time where other strategies quickly fail. "}],"type":"conference","date_updated":"2025-06-04T08:18:32Z","publication_status":"published","department":[{"_id":"ChLa"},{"_id":"ChWo"}],"ec_funded":1,"day":"14","doi":"10.1109/CVPR.2017.587","month":"04","oa_version":"Submitted Version","language":[{"iso":"eng"}],"quality_controlled":"1","arxiv":1,"citation":{"ista":"Rebuffi SA, Kolesnikov A, Sperl G, Lampert C. 2017. iCaRL: Incremental classifier and representation learning. CVPR: Computer Vision and Pattern Recognition vol. 2017, 5533–5542.","mla":"Rebuffi, Sylvestre Alvise, et al. <i>ICaRL: Incremental Classifier and Representation Learning</i>. Vol. 2017, IEEE, 2017, pp. 5533–42, doi:<a href=\"https://doi.org/10.1109/CVPR.2017.587\">10.1109/CVPR.2017.587</a>.","chicago":"Rebuffi, Sylvestre Alvise, Alexander Kolesnikov, Georg Sperl, and Christoph Lampert. “ICaRL: Incremental Classifier and Representation Learning,” 2017:5533–42. IEEE, 2017. <a href=\"https://doi.org/10.1109/CVPR.2017.587\">https://doi.org/10.1109/CVPR.2017.587</a>.","short":"S.A. Rebuffi, A. Kolesnikov, G. Sperl, C. Lampert, in:, IEEE, 2017, pp. 5533–5542.","ama":"Rebuffi SA, Kolesnikov A, Sperl G, Lampert C. iCaRL: Incremental classifier and representation learning. In: Vol 2017. IEEE; 2017:5533-5542. doi:<a href=\"https://doi.org/10.1109/CVPR.2017.587\">10.1109/CVPR.2017.587</a>","apa":"Rebuffi, S. A., Kolesnikov, A., Sperl, G., &#38; Lampert, C. (2017). iCaRL: Incremental classifier and representation learning (Vol. 2017, pp. 5533–5542). Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2017.587\">https://doi.org/10.1109/CVPR.2017.587</a>","ieee":"S. A. Rebuffi, A. Kolesnikov, G. Sperl, and C. Lampert, “iCaRL: Incremental classifier and representation learning,” presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 5533–5542."},"main_file_link":[{"url":"https://arxiv.org/abs/1611.07725","open_access":"1"}],"status":"public","scopus_import":"1"},{"year":"2017","publisher":"ML Research Press","project":[{"_id":"2532554C-B435-11E9-9278-68D0E5697425","grant_number":"308036","name":"Lifelong Learning of Visual Scene Understanding","call_identifier":"FP7"}],"page":"2807 - 2816","article_processing_charge":"No","date_published":"2017-06-08T00:00:00Z","volume":70,"publist_id":"6399","intvolume":"        70","author":[{"first_name":"Anastasia","full_name":"Pentina, Anastasia","id":"42E87FC6-F248-11E8-B48F-1D18A9856A87","last_name":"Pentina"},{"full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","last_name":"Lampert","orcid":"0000-0001-8622-7887","first_name":"Christoph"}],"isi":1,"external_id":{"arxiv":["1602.06518"],"isi":["000683309502093"]},"_id":"999","alternative_title":["PMLR"],"scopus_import":"1","citation":{"ieee":"A. Pentina and C. Lampert, “Multi-task learning with labeled and unlabeled tasks,” presented at the ICML: International Conference on Machine Learning, Sydney, Australia, 2017, vol. 70, pp. 2807–2816.","apa":"Pentina, A., &#38; Lampert, C. (2017). Multi-task learning with labeled and unlabeled tasks (Vol. 70, pp. 2807–2816). Presented at the ICML: International Conference on Machine Learning, Sydney, Australia: ML Research Press.","ama":"Pentina A, Lampert C. Multi-task learning with labeled and unlabeled tasks. In: Vol 70. ML Research Press; 2017:2807-2816.","chicago":"Pentina, Anastasia, and Christoph Lampert. “Multi-Task Learning with Labeled and Unlabeled Tasks,” 70:2807–16. ML Research Press, 2017.","short":"A. Pentina, C. Lampert, in:, ML Research Press, 2017, pp. 2807–2816.","mla":"Pentina, Anastasia, and Christoph Lampert. <i>Multi-Task Learning with Labeled and Unlabeled Tasks</i>. Vol. 70, ML Research Press, 2017, pp. 2807–16.","ista":"Pentina A, Lampert C. 2017. Multi-task learning with labeled and unlabeled tasks. ICML: International Conference on Machine Learning, PMLR, vol. 70, 2807–2816."},"status":"public","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1602.06518"}],"quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Submitted Version","arxiv":1,"ec_funded":1,"day":"08","publication_status":"published","department":[{"_id":"ChLa"}],"month":"06","corr_author":"1","date_updated":"2025-06-04T08:19:03Z","type":"conference","publication_identifier":{"isbn":["9781510855144"]},"date_created":"2018-12-11T11:49:37Z","abstract":[{"lang":"eng","text":"In multi-task learning, a learner is given a collection of prediction tasks and needs to solve all of them. In contrast to previous work, which required that annotated training data must be available for all tasks, we consider a new setting, in which for some tasks, potentially most of them, only unlabeled training data is provided. Consequently, to solve all tasks, information must be transferred between tasks with labels and tasks without labels. Focusing on an instance-based transfer method we analyze two variants of this setting: when the set of labeled tasks is fixed, and when it can be actively selected by the learner. We state and prove a generalization bound that covers both scenarios and derive from it an algorithm for making the choice of labeled tasks (in the active case) and for transferring information between the tasks in a principled way. We also illustrate the effectiveness of the algorithm on synthetic and real data. "}],"oa":1,"conference":{"name":"ICML: International Conference on Machine Learning","start_date":"2017-08-06","location":"Sydney, Australia","end_date":"2017-08-11"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Multi-task learning with labeled and unlabeled tasks"},{"publisher":"eLife Sciences Publications","ddc":["576"],"article_number":"e25100","pubrep_id":"890","year":"2017","date_published":"2017-07-25T00:00:00Z","article_processing_charge":"No","intvolume":"         6","publist_id":"6990","volume":6,"external_id":{"isi":["000406183700001"]},"_id":"704","isi":1,"author":[{"first_name":"Magdalena","orcid":"0000-0003-1229-9719","id":"2C023F40-F248-11E8-B48F-1D18A9856A87","full_name":"Steinrück, Magdalena","last_name":"Steinrück"},{"full_name":"Guet, Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet","orcid":"0000-0001-6220-2052","first_name":"Calin C"}],"status":"public","citation":{"chicago":"Steinrück, Magdalena, and Calin C Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>.","mla":"Steinrück, Magdalena, and Calin C. Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>, vol. 6, e25100, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>.","short":"M. Steinrück, C.C. Guet, ELife 6 (2017).","ista":"Steinrück M, Guet CC. 2017. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. eLife. 6, e25100.","ieee":"M. Steinrück and C. C. Guet, “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.","apa":"Steinrück, M., &#38; Guet, C. C. (2017). Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>","ama":"Steinrück M, Guet CC. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>"},"file":[{"relation":"main_file","checksum":"6b908b5db9f61f6820ebd7f8fa815571","content_type":"application/pdf","access_level":"open_access","file_size":2092088,"creator":"system","date_updated":"2020-07-14T12:47:48Z","file_name":"IST-2017-890-v1+1_elife-25100-v1.pdf","file_id":"4975","date_created":"2018-12-12T10:12:54Z"},{"file_name":"IST-2017-890-v1+2_elife-25100-figures-v1.pdf","file_id":"4976","date_created":"2018-12-12T10:12:55Z","file_size":3428681,"creator":"system","date_updated":"2020-07-14T12:47:48Z","access_level":"open_access","relation":"main_file","checksum":"ca21530389b720243552678125fdba35","content_type":"application/pdf"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"scopus_import":"1","month":"07","corr_author":"1","related_material":{"record":[{"relation":"popular_science","id":"5564","status":"public"},{"status":"public","relation":"dissertation_contains","id":"26"}]},"doi":"10.7554/eLife.25100","day":"25","publication_status":"published","department":[{"_id":"CaGu"}],"language":[{"iso":"eng"}],"oa_version":"Published Version","quality_controlled":"1","abstract":[{"lang":"eng","text":"How the organization of genes on a chromosome shapes adaptation is essential for understanding evolutionary paths. Here, we investigate how adaptation to rapidly increasing levels of antibiotic depends on the chromosomal neighborhood of a drug-resistance gene inserted at different positions of the Escherichia coli chromosome. Using a dual-fluorescence reporter that allows us to distinguish gene amplifications from other up-mutations, we track in real-time adaptive changes in expression of the drug-resistance gene. We find that the relative contribution of several mutation types differs systematically between loci due to properties of neighboring genes: essentiality, expression, orientation, termination, and presence of duplicates. These properties determine rate and fitness effects of gene amplification, deletions, and mutations compromising transcriptional termination. Thus, the adaptive potential of a gene under selection is a system-property with a complex genetic basis that is specific for each chromosomal locus, and it can be inferred from detailed functional and genomic data."}],"publication_identifier":{"issn":["2050-084X"]},"date_created":"2018-12-11T11:48:01Z","publication":"eLife","file_date_updated":"2020-07-14T12:47:48Z","date_updated":"2026-06-24T22:30:07Z","type":"journal_article","title":"Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","has_accepted_license":"1","oa":1},{"intvolume":"       127","publist_id":"7038","volume":127,"external_id":{"pmid":["28504646"],"isi":["000402620800008"]},"_id":"679","issue":"6","isi":1,"author":[{"last_name":"Ebner","full_name":"Ebner, Florian","first_name":"Florian"},{"first_name":"Vitaly","full_name":"Sedlyarov, Vitaly","last_name":"Sedlyarov"},{"orcid":"0000-0003-1671-393X","first_name":"Saren","full_name":"Tasciyan, Saren","id":"4323B49C-F248-11E8-B48F-1D18A9856A87","last_name":"Tasciyan"},{"first_name":"Masa","last_name":"Ivin","full_name":"Ivin, Masa"},{"first_name":"Franz","full_name":"Kratochvill, Franz","last_name":"Kratochvill"},{"first_name":"Nina","last_name":"Gratz","full_name":"Gratz, Nina"},{"full_name":"Kenner, Lukas","last_name":"Kenner","first_name":"Lukas"},{"first_name":"Andreas","full_name":"Villunger, Andreas","last_name":"Villunger"},{"full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","orcid":"0000-0002-6620-9179","first_name":"Michael K"},{"first_name":"Pavel","full_name":"Kovarik, Pavel","last_name":"Kovarik"}],"project":[{"_id":"25985A36-B435-11E9-9278-68D0E5697425","grant_number":"T00817-B21","call_identifier":"FWF","name":"The biochemical basis of PAR polarization"},{"_id":"25E9AF9E-B435-11E9-9278-68D0E5697425","grant_number":"P27201-B22","call_identifier":"FWF","name":"Revealing the mechanisms underlying drug interactions"}],"publisher":"American Society for Clinical Investigation","year":"2017","pmid":1,"date_published":"2017-06-01T00:00:00Z","article_processing_charge":"No","page":"2051 - 2065","abstract":[{"text":"Protective responses against pathogens require a rapid mobilization of resting neutrophils and the timely removal of activated ones. Neutrophils are exceptionally short-lived leukocytes, yet it remains unclear whether the lifespan of pathogen-engaged neutrophils is regulated differently from that in the circulating steady-state pool. Here, we have found that under homeostatic conditions, the mRNA-destabilizing protein tristetraprolin (TTP) regulates apoptosis and the numbers of activated infiltrating murine neutrophils but not neutrophil cellularity. Activated TTP-deficient neutrophils exhibited decreased apoptosis and enhanced accumulation at the infection site. In the context of myeloid-specific deletion of Ttp, the potentiation of neutrophil deployment protected mice against lethal soft tissue infection with Streptococcus pyogenes and prevented bacterial dissemination. Neutrophil transcriptome analysis revealed that decreased apoptosis of TTP-deficient neutrophils was specifically associated with elevated expression of myeloid cell leukemia 1 (Mcl1) but not other antiapoptotic B cell leukemia/ lymphoma 2 (Bcl2) family members. Higher Mcl1 expression resulted from stabilization of Mcl1 mRNA in the absence of TTP. The low apoptosis rate of infiltrating TTP-deficient neutrophils was comparable to that of transgenic Mcl1-overexpressing neutrophils. Our study demonstrates that posttranscriptional gene regulation by TTP schedules the termination of the antimicrobial engagement of neutrophils. The balancing role of TTP comes at the cost of an increased risk of bacterial infections.","lang":"eng"}],"date_created":"2018-12-11T11:47:53Z","publication":"The Journal of Clinical Investigation","publication_identifier":{"issn":["0021-9738"]},"type":"journal_article","date_updated":"2026-06-24T22:30:09Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection","oa":1,"status":"public","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451238/"}],"citation":{"ista":"Ebner F, Sedlyarov V, Tasciyan S, Ivin M, Kratochvill F, Gratz N, Kenner L, Villunger A, Sixt MK, Kovarik P. 2017. The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. The Journal of Clinical Investigation. 127(6), 2051–2065.","short":"F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.","mla":"Ebner, Florian, et al. “The RNA-Binding Protein Tristetraprolin Schedules Apoptosis of Pathogen-Engaged Neutrophils during Bacterial Infection.” <i>The Journal of Clinical Investigation</i>, vol. 127, no. 6, American Society for Clinical Investigation, 2017, pp. 2051–65, doi:<a href=\"https://doi.org/10.1172/JCI80631\">10.1172/JCI80631</a>.","chicago":"Ebner, Florian, Vitaly Sedlyarov, Saren Tasciyan, Masa Ivin, Franz Kratochvill, Nina Gratz, Lukas Kenner, Andreas Villunger, Michael K Sixt, and Pavel Kovarik. “The RNA-Binding Protein Tristetraprolin Schedules Apoptosis of Pathogen-Engaged Neutrophils during Bacterial Infection.” <i>The Journal of Clinical Investigation</i>. American Society for Clinical Investigation, 2017. <a href=\"https://doi.org/10.1172/JCI80631\">https://doi.org/10.1172/JCI80631</a>.","ama":"Ebner F, Sedlyarov V, Tasciyan S, et al. The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. <i>The Journal of Clinical Investigation</i>. 2017;127(6):2051-2065. doi:<a href=\"https://doi.org/10.1172/JCI80631\">10.1172/JCI80631</a>","apa":"Ebner, F., Sedlyarov, V., Tasciyan, S., Ivin, M., Kratochvill, F., Gratz, N., … Kovarik, P. (2017). The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. <i>The Journal of Clinical Investigation</i>. American Society for Clinical Investigation. <a href=\"https://doi.org/10.1172/JCI80631\">https://doi.org/10.1172/JCI80631</a>","ieee":"F. Ebner <i>et al.</i>, “The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection,” <i>The Journal of Clinical Investigation</i>, vol. 127, no. 6. American Society for Clinical Investigation, pp. 2051–2065, 2017."},"acknowledgement":"This work was supported by grants from the Austrian Science Fund (FWF) (P27538-B21, I1621-B22, and SFB 43, to PK); by funding from the European Union Seventh Framework Programme Marie Curie Initial Training Networks (FP7-PEOPLE-2012-ITN) for the project INBIONET (INfection BIOlogy Training NETwork under grant agreement PITN-GA-2012-316682; and by a joint research cluster initiative of the University of Vienna and the Medical University of Vienna.","scopus_import":"1","related_material":{"record":[{"id":"12401","relation":"dissertation_contains","status":"public"}]},"month":"06","department":[{"_id":"MiSi"}],"publication_status":"published","doi":"10.1172/JCI80631","day":"01","language":[{"iso":"eng"}],"oa_version":"Submitted Version","quality_controlled":"1"},{"article_number":"e0179377","pubrep_id":"897","year":"2017","ddc":["571"],"publisher":"Public Library of Science","article_processing_charge":"No","date_published":"2017-06-01T00:00:00Z","volume":12,"publist_id":"7034","intvolume":"        12","author":[{"first_name":"Hikari","full_name":"Ukai, Hikari","last_name":"Ukai"},{"first_name":"Aiko","full_name":"Kawahara, Aiko","last_name":"Kawahara"},{"first_name":"Keiko","full_name":"Hirayama, Keiko","last_name":"Hirayama"},{"last_name":"Case","id":"44B7CA5A-F248-11E8-B48F-1D18A9856A87","full_name":"Case, Matthew J","first_name":"Matthew J"},{"full_name":"Aino, Shotaro","last_name":"Aino","first_name":"Shotaro"},{"first_name":"Masahiro","last_name":"Miyabe","full_name":"Miyabe, Masahiro"},{"full_name":"Wakita, Ken","last_name":"Wakita","first_name":"Ken"},{"first_name":"Ryohei","last_name":"Oogi","full_name":"Oogi, Ryohei"},{"first_name":"Michiyo","last_name":"Kasayuki","full_name":"Kasayuki, Michiyo"},{"full_name":"Kawashima, Shihomi","last_name":"Kawashima","first_name":"Shihomi"},{"full_name":"Sugimoto, Shunichi","last_name":"Sugimoto","first_name":"Shunichi"},{"first_name":"Kanako","last_name":"Chikamatsu","full_name":"Chikamatsu, Kanako"},{"first_name":"Noritaka","full_name":"Nitta, Noritaka","last_name":"Nitta"},{"first_name":"Tsuneyuki","full_name":"Koga, Tsuneyuki","last_name":"Koga"},{"orcid":"0000-0001-8761-9444","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Toshiyuki","last_name":"Takai","full_name":"Takai, Toshiyuki"},{"first_name":"Isao","last_name":"Ito","full_name":"Ito, Isao"}],"isi":1,"issue":"6","_id":"682","external_id":{"isi":["000402923200125"]},"scopus_import":"1","file":[{"access_level":"open_access","content_type":"application/pdf","relation":"main_file","checksum":"24dd19c46fb1c761b0bcbbcd1025a3a8","file_id":"4934","date_created":"2018-12-12T10:12:16Z","file_name":"IST-2017-897-v1+1_journal.pone.0179377.pdf","date_updated":"2020-07-14T12:47:40Z","file_size":5798454,"creator":"system"}],"citation":{"ama":"Ukai H, Kawahara A, Hirayama K, et al. PirB regulates asymmetries in hippocampal circuitry. <i>PLoS One</i>. 2017;12(6). doi:<a href=\"https://doi.org/10.1371/journal.pone.0179377\">10.1371/journal.pone.0179377</a>","apa":"Ukai, H., Kawahara, A., Hirayama, K., Case, M. J., Aino, S., Miyabe, M., … Ito, I. (2017). PirB regulates asymmetries in hippocampal circuitry. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0179377\">https://doi.org/10.1371/journal.pone.0179377</a>","ieee":"H. Ukai <i>et al.</i>, “PirB regulates asymmetries in hippocampal circuitry,” <i>PLoS One</i>, vol. 12, no. 6. Public Library of Science, 2017.","ista":"Ukai H, Kawahara A, Hirayama K, Case MJ, Aino S, Miyabe M, Wakita K, Oogi R, Kasayuki M, Kawashima S, Sugimoto S, Chikamatsu K, Nitta N, Koga T, Shigemoto R, Takai T, Ito I. 2017. PirB regulates asymmetries in hippocampal circuitry. PLoS One. 12(6), e0179377.","chicago":"Ukai, Hikari, Aiko Kawahara, Keiko Hirayama, Matthew J Case, Shotaro Aino, Masahiro Miyabe, Ken Wakita, et al. “PirB Regulates Asymmetries in Hippocampal Circuitry.” <i>PLoS One</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pone.0179377\">https://doi.org/10.1371/journal.pone.0179377</a>.","mla":"Ukai, Hikari, et al. “PirB Regulates Asymmetries in Hippocampal Circuitry.” <i>PLoS One</i>, vol. 12, no. 6, e0179377, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pone.0179377\">10.1371/journal.pone.0179377</a>.","short":"H. Ukai, A. Kawahara, K. Hirayama, M.J. Case, S. Aino, M. Miyabe, K. Wakita, R. Oogi, M. Kasayuki, S. Kawashima, S. Sugimoto, K. Chikamatsu, N. Nitta, T. Koga, R. Shigemoto, T. Takai, I. Ito, PLoS One 12 (2017)."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","quality_controlled":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"doi":"10.1371/journal.pone.0179377","day":"01","department":[{"_id":"RySh"}],"publication_status":"published","month":"06","related_material":{"record":[{"id":"51","relation":"dissertation_contains","status":"public"}]},"date_updated":"2026-06-24T22:30:34Z","type":"journal_article","file_date_updated":"2020-07-14T12:47:40Z","publication_identifier":{"issn":["1932-6203"]},"date_created":"2018-12-11T11:47:54Z","publication":"PLoS One","abstract":[{"lang":"eng","text":"Left-right asymmetry is a fundamental feature of higher-order brain structure; however, the molecular basis of brain asymmetry remains unclear. We recently identified structural and functional asymmetries in mouse hippocampal circuitry that result from the asymmetrical distribution of two distinct populations of pyramidal cell synapses that differ in the density of the NMDA receptor subunit GluRε2 (also known as NR2B, GRIN2B or GluN2B). By examining the synaptic distribution of ε2 subunits, we previously found that β2-microglobulin-deficient mice, which lack cell surface expression of the vast majority of major histocompatibility complex class I (MHCI) proteins, do not exhibit circuit asymmetry. In the present study, we conducted electrophysiological and anatomical analyses on the hippocampal circuitry of mice with a knockout of the paired immunoglobulin-like receptor B (PirB), an MHCI receptor. As in β2-microglobulin-deficient mice, the PirB-deficient hippocampus lacked circuit asymmetries. This finding that MHCI loss-of-function mice and PirB knockout mice have identical phenotypes suggests that MHCI signals that produce hippocampal asymmetries are transduced through PirB. Our results provide evidence for a critical role of the MHCI/PirB signaling system in the generation of asymmetries in hippocampal circuitry."}],"has_accepted_license":"1","oa":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"PirB regulates asymmetries in hippocampal circuitry","article_type":"original"}]