[{"date_created":"2026-02-09T14:59:53Z","supervisor":[{"orcid":"0000-0001-8622-7887","first_name":"Christoph","full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","last_name":"Lampert"}],"publication_identifier":{"issn":["2663-337X"]},"abstract":[{"lang":"eng","text":"In recent years there has been a massive increase in the amount of data generated in a\r\ndecentralized manner. Ever more powerful edge devices, such as smartphones, have become\r\nubiquitous in most societies on earth. Through text typed, photos taken and apps used,\r\nthese devices, which we refer to as clients, generate enormous amounts of high quality and\r\ncomplex data. Moreover, the nature of these devices means the data they generate is often\r\nsensitive and privacy concerns prevent it being gathered and stored in a central location. This\r\npresents a challenge to the modern machine learning paradigm that requires central access\r\nto large amounts of data. Federated learning (FL) has emerged as one of the answers to\r\nthis problem. Rather than bringing the data to the model, FL sends the model to the data.\r\nModel training takes place on device, with periodically synchronized updates, allowing data to\r\nremain locally stored. While this approach offers significant privacy advantages it comes with\r\nits own set of unique challenges. These include: data heterogeneity, the notion that different\r\ndevices generate data in distinct ways which can negatively impact training dynamics; systems\r\nheterogeneity, meaning that different devices may have differing hardware specifications; high\r\ncommunication costs, which are induced by the repeated transferring of models over the\r\nnetwork and low device computational power, which limits the use of larger models on device.\r\nIn this thesis we present a range of methods for federated learning. We focus primarily on\r\nthe challenge of data heterogeneity, though the methods presented are designed to be well\r\nadapted to the other challenges of a federated setting, such as the constraints of limited\r\ncompute and communication overhead. We first present a method for explicitly modeling client\r\ndata heterogeneity. The approach formulates clients as samples from a certain probability\r\ndistribution and infers the parameters of this distribution from the available training clients.\r\nThis learned distribution then represents the heterogeneity present among the clients and can\r\nbe sampled from in order to create new simulated clients that are similar to the real clients we\r\nhave observed so far. Following this we present two methods for directly dealing with data\r\nheterogeneity through personalization. Highly heterogeneous client data distributions can mean\r\nthat learning a single global model becomes suboptimal, and some form of personalization of\r\nmodels to each individual client is required. Our approaches are based around hypernetworks,\r\nwhich we use to generate personalized model parameters without the need for additional\r\ntraining or finetuning. In the first approach we focus on generating full parameterizations of\r\nclient models using learned embeddings of client data and labels, with a hypernetwork located\r\non the central server. In the second approach we address the more challenging scenario where\r\nwe want to generate a personalized model for a client without any label information. The\r\nhypernetwork is trained to generate a low dimensional representation of a client’s personalized\r\nmodel parameters, allowing it to be transferred to and run on the client devices. In our final\r\npresented method, we change our focus and rather than aim to directly address the challenge\r\nof data heterogeneity, we instead ensure we are unaffected by it. This is done in the context\r\nof k-means clustering and we present a method for federated clustering with a focus on added\r\nprivacy guarantees."}],"type":"dissertation","date_updated":"2026-04-07T11:46:11Z","file_date_updated":"2026-02-27T10:25:41Z","title":"Data heterogeneity and personalization in federated learning","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","oa":1,"has_accepted_license":"1","citation":{"apa":"Scott, J. A. (2026). <i>Data heterogeneity and personalization in federated learning</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>","ama":"Scott JA. Data heterogeneity and personalization in federated learning. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>","ieee":"J. A. Scott, “Data heterogeneity and personalization in federated learning,” Institute of Science and Technology Austria, 2026.","ista":"Scott JA. 2026. Data heterogeneity and personalization in federated learning. Institute of Science and Technology Austria.","chicago":"Scott, Jonathan A. “Data Heterogeneity and Personalization in Federated Learning.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>.","short":"J.A. Scott, Data Heterogeneity and Personalization in Federated Learning, Institute of Science and Technology Austria, 2026.","mla":"Scott, Jonathan A. <i>Data Heterogeneity and Personalization in Federated Learning</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>."},"file":[{"file_name":"2026_Scott_Jonathan_Thesis_Source.zip","file_id":"21298","date_created":"2026-02-17T11:46:22Z","file_size":272379252,"creator":"jscott","date_updated":"2026-02-17T11:46:22Z","access_level":"closed","relation":"source_file","checksum":"121c1d968bd86f3630aa7e81d5bbbcb0","content_type":"application/zip"},{"content_type":"application/pdf","checksum":"6e3e08ba474bbee8511cc8a839ab2077","relation":"main_file","access_level":"open_access","success":1,"date_updated":"2026-02-27T10:25:41Z","creator":"jscott","file_size":15220298,"date_created":"2026-02-27T10:25:41Z","file_id":"21366","file_name":"2026_Jonathan_Scott_Thesis.pdf"}],"status":"public","acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF)\r\n[10.55776/COE12]. Furthermore, the candidate acknowledges the support from the Scientific\r\nService Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).","publication_status":"published","department":[{"_id":"GradSch"},{"_id":"ChLa"}],"doi":"10.15479/AT-ISTA-21198","day":"09","related_material":{"record":[{"status":"public","id":"20819","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"17411","status":"public"},{"status":"public","id":"18120","relation":"part_of_dissertation"},{"status":"public","id":"21207","relation":"part_of_dissertation"}]},"month":"02","corr_author":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"ScienComp"}],"alternative_title":["ISTA Thesis"],"_id":"21198","author":[{"first_name":"Jonathan A","full_name":"Scott, Jonathan A","id":"e499926b-f6e0-11ea-865d-9c63db0031e8","last_name":"Scott"}],"ddc":["005"],"publisher":"Institute of Science and Technology Austria","year":"2026","degree_awarded":"PhD","date_published":"2026-02-09T00:00:00Z","page":"158","article_processing_charge":"No"},{"date_published":"2026-01-16T00:00:00Z","month":"01","department":[{"_id":"SiHi"}],"publication_status":"published","day":"16","doi":"10.64898/2026.01.15.699808","article_processing_charge":"No","language":[{"iso":"eng"}],"oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.64898/2026.01.15.699808","open_access":"1"}],"status":"public","ddc":["570"],"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"citation":{"ista":"Jiang Y, Ahn R, Huang A, Gonzalez PP, Kim J, Zhang G, Liu Z, He Z, Dudley L, Patel KS, Dzhivhuho GA, Crowl S, Przanowski P, Camacho LQ, Hao S, Zeng J, Hippenmeyer S, Fallahi-Sichani M, Janes KA, Naegle KM, Hammarskjold M-L, Goldman SA, Kornblum HI, Yao M, White F, Zong H. 2026. Critical role of cell competition in gliomagenesis. bioRxiv, <a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>.","mla":"Jiang, Ying, et al. “Critical Role of Cell Competition in Gliomagenesis.” <i>BioRxiv</i>, 2026, doi:<a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>.","short":"Y. Jiang, R. Ahn, A. Huang, P.P. Gonzalez, J. Kim, G. Zhang, Z. Liu, Z. He, L. Dudley, K.S. Patel, G.A. Dzhivhuho, S. Crowl, P. Przanowski, L.Q. Camacho, S. Hao, J. Zeng, S. Hippenmeyer, M. Fallahi-Sichani, K.A. Janes, K.M. Naegle, M.-L. Hammarskjold, S.A. Goldman, H.I. Kornblum, M. Yao, F. White, H. Zong, BioRxiv (2026).","chicago":"Jiang, Ying, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun Kim, Guoxin Zhang, Zihao Liu, et al. “Critical Role of Cell Competition in Gliomagenesis.” <i>BioRxiv</i>, 2026. <a href=\"https://doi.org/10.64898/2026.01.15.699808\">https://doi.org/10.64898/2026.01.15.699808</a>.","apa":"Jiang, Y., Ahn, R., Huang, A., Gonzalez, P. P., Kim, J., Zhang, G., … Zong, H. (2026). Critical role of cell competition in gliomagenesis. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.01.15.699808\">https://doi.org/10.64898/2026.01.15.699808</a>","ama":"Jiang Y, Ahn R, Huang A, et al. Critical role of cell competition in gliomagenesis. <i>bioRxiv</i>. 2026. doi:<a href=\"https://doi.org/10.64898/2026.01.15.699808\">10.64898/2026.01.15.699808</a>","ieee":"Y. Jiang <i>et al.</i>, “Critical role of cell competition in gliomagenesis,” <i>bioRxiv</i>. 2026."},"acknowledgement":"We thank Dr. Wenjie Liu for providing critical feedback on the manuscript. We also thank Dr.\r\nPat Pramoonjago at the Biorepository and Tissue Research Facility, and Hope Davis at the\r\nvivarium for their assistance on the project. These Core Facilities are supported by UVA Cancer\r\nCenter grant #P30-CA044579. We are grateful to Dr. Jonathan A. Epstein for providing the\r\nNf1GRD/+ mouse strain (https://pubmed.ncbi.nlm.nih.gov/26460546/). This work was partly\r\nsupported by the National Institute of Neurological Diseases and Stroke R21 NS125479-01A1\r\n(H.Z.), American Cancer Society Institutional Research Grant to the University of Virginia\r\n(Y.J.), the National Natural Science Foundation of China #82072787 (M.Y.), the National\r\nCancer Institute U54 CA238114 (F.W.), U01 CA284193 (K.M.N.), and U54 CA274499 (K.A.J.,\r\nM.F-S.), the National institute of General Medical Sciences R35 GM133404 (M.F-S.), the Dr.\r\nMiriam and Sheldon G. Adelson Medical Research Foundation (H.I.K., S.A.G.), the National\r\nCenter for Advancing Translational Sciences KL2TR001882 (K.S.P.), Tower Cancer Career Development Grant (K.S.P.), McKnight Neurobiology of Brain Disorders Grant (K.S.P.). The\r\ncontent is solely the responsibility of the authors and does not necessarily represent the official\r\nviews of the National Institutes of Health. Illustrations in this manuscript were created with\r\nBioRender (BioRender.com).","year":"2026","OA_place":"repository","title":"Critical role of cell competition in gliomagenesis","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"21212","OA_type":"green","author":[{"last_name":"Jiang","full_name":"Jiang, Ying","first_name":"Ying"},{"first_name":"Ryuhjin","last_name":"Ahn","full_name":"Ahn, Ryuhjin"},{"last_name":"Huang","full_name":"Huang, Arthur","first_name":"Arthur"},{"last_name":"Gonzalez","full_name":"Gonzalez, Phillippe P.","first_name":"Phillippe P."},{"last_name":"Kim","full_name":"Kim, Jungeun","first_name":"Jungeun"},{"first_name":"Guoxin","last_name":"Zhang","full_name":"Zhang, Guoxin"},{"first_name":"Zihao","last_name":"Liu","full_name":"Liu, Zihao"},{"last_name":"He","full_name":"He, Zhenqiang","first_name":"Zhenqiang"},{"first_name":"Lindsey","last_name":"Dudley","full_name":"Dudley, Lindsey"},{"full_name":"Patel, Kunal S.","last_name":"Patel","first_name":"Kunal S."},{"last_name":"Dzhivhuho","full_name":"Dzhivhuho, Godfrey A.","first_name":"Godfrey A."},{"last_name":"Crowl","full_name":"Crowl, Sam","first_name":"Sam"},{"full_name":"Przanowski, Piotr","last_name":"Przanowski","first_name":"Piotr"},{"full_name":"Camacho, Luisa Quesada","last_name":"Camacho","first_name":"Luisa Quesada"},{"first_name":"Sijie","full_name":"Hao, Sijie","last_name":"Hao"},{"last_name":"Zeng","full_name":"Zeng, Jianhao","first_name":"Jianhao"},{"first_name":"Simon","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"},{"last_name":"Fallahi-Sichani","full_name":"Fallahi-Sichani, Mohammad","first_name":"Mohammad"},{"full_name":"Janes, Kevin A.","last_name":"Janes","first_name":"Kevin A."},{"first_name":"Kristen M.","last_name":"Naegle","full_name":"Naegle, Kristen M."},{"first_name":"Marie-Louise","full_name":"Hammarskjold, Marie-Louise","last_name":"Hammarskjold"},{"full_name":"Goldman, Steven A.","last_name":"Goldman","first_name":"Steven A."},{"last_name":"Kornblum","full_name":"Kornblum, Harley I.","first_name":"Harley I."},{"full_name":"Yao, Maojin","last_name":"Yao","first_name":"Maojin"},{"first_name":"Forest","last_name":"White","full_name":"White, Forest"},{"last_name":"Zong","full_name":"Zong, Hui","first_name":"Hui"}],"has_accepted_license":"1","oa":1,"abstract":[{"text":"Malignant glioma is incurable. Using a mouse genetic mosaic system to generate sporadic Trp53,Nf1-null OPCs, we previously identified oligodendrocyte precursor cell (OPC) as a cell-of-origin of glioma. Here, we report that pre-malignant Trp53,Nf1-null OPCs outcompete wildtype counterparts during their expansion. Blocking competition by mutating/strengthening wildtype OPCs impeded both pre-malignant progression and malignant expansion of glioma.\r\n\r\n“In-tissue” phosphoproteomic profiling revealed an enrichment of phosphopeptides related to RNA splicing and protein translation at the peak of cell competition, suggesting that competitiveness may stem from unique protein species. Among candidates was mTORC1, whose pharmacological inhibition or genetic disruption resulted in a loss of competitiveness in our mouse model. Finally, analysis of patient biopsies and interrogating the role of individual gliomagenic mutations in OPC competition supported its relevance in human gliomas. Together, these findings identified the driving role of competitive interactions among OPCs in gliomagenesis, and suggest unconventional therapeutic strategies to target this process.","lang":"eng"}],"date_created":"2026-02-10T12:55:55Z","publication":"bioRxiv","type":"preprint","date_updated":"2026-02-16T10:12:42Z"},{"author":[{"last_name":"Casallas Garcia","full_name":"Casallas Garcia, Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","orcid":"0000-0002-1988-5035","first_name":"Alejandro"},{"first_name":"Adrian","last_name":"Mark Tompkins","full_name":"Mark Tompkins, Adrian"},{"first_name":"Caroline J","orcid":"0000-0001-5836-5350","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","full_name":"Muller, Caroline J","last_name":"Muller"}],"_id":"21217","year":"2026","article_number":"e70131","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"_id":"629205d8-2b32-11ec-9570-e1356ff73576","grant_number":"805041","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","call_identifier":"H2020"}],"publisher":"Wiley","ddc":["550"],"article_processing_charge":"Yes (via OA deal)","date_published":"2026-02-12T00:00:00Z","type":"journal_article","date_updated":"2026-02-16T10:19:52Z","abstract":[{"lang":"eng","text":"This study investigates the mechanisms driving clustered convection and the breakdown of the Intertropical Convergence Zone (ITCZ) over the Western Pacific Warm Pool using high‐resolution cloud‐resolving simulations and machine‐learning sensitivity experiments. Results show that ITCZ breakdown episodes, marked by spatially homogeneous convection and weakened meridional moisture gradients, are triggered primarily by anomalous moisture advection linked to the equatorial Rossby‐wave activity. While large‐scale moisture advection regulates the background convective state strongly, it is the surface and low‐level meridional winds that dominate transitions between clustered and random convection. Simulations demonstrate that moisture alone can sustain convective clustering, but breakdown episodes are more persistent and widespread when coupled with southerly meridional advection. These findings confirm that wave‐driven advection acts as a regulatory mechanism, periodically disrupting convective clustering and reshaping the meridional moisture gradient. This modulation of organization by wave‐induced breakdown events is critical for understanding tropical convection variability and its implications for the climate system."}],"publication":"Quarterly Journal of the Royal Meteorological Society","date_created":"2026-02-12T10:13:02Z","publication_identifier":{"issn":["0035-9009"],"eissn":["1477-870X"]},"oa":1,"has_accepted_license":"1","article_type":"original","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events","OA_type":"hybrid","acknowledgement":"This article is based on chapter 5 of the PhD thesis of A. Casallas. The authors thank Graziano Giuliani for discussions on the boundary-condition experiments. A. Casallas was supported by a PhD fellowship awarded by the Abdus Salam International Centre for Theoretical Physics. A. Casallas also acknowledges support by the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 101034413. C. Muller acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). The authors gratefully acknowledge Daniel Hernández-Deckers, Lokahith Agasthya, Chris Holloway, and Paolina Cerlini for their valuable feedback and insightful discussions. They are especially thankful to Bety Pechacova for suggesting the use of SHAP to complement their analysis. They also thank the two anonymous reviewers for their constructive comments, which improved the quality and clarity of the article significantly. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","scopus_import":"1","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1002/qj.70131"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"citation":{"mla":"Casallas Garcia, Alejandro, et al. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>, e70131, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>.","chicago":"Casallas Garcia, Alejandro, Adrian Mark Tompkins, and Caroline J Muller. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>.","short":"A. Casallas Garcia, A. Mark Tompkins, C.J. Muller, Quarterly Journal of the Royal Meteorological Society (2026).","ista":"Casallas Garcia A, Mark Tompkins A, Muller CJ. 2026. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society., e70131.","ieee":"A. Casallas Garcia, A. Mark Tompkins, and C. J. Muller, “Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events,” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026.","apa":"Casallas Garcia, A., Mark Tompkins, A., &#38; Muller, C. J. (2026). Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>","ama":"Casallas Garcia A, Mark Tompkins A, Muller CJ. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. 2026. doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>"},"language":[{"iso":"eng"}],"oa_version":"Published Version","quality_controlled":"1","month":"02","corr_author":"1","publication_status":"epub_ahead","department":[{"_id":"CaMu"}],"day":"12","doi":"10.1002/qj.70131","ec_funded":1},{"publication_identifier":{"isbn":["9780443214400"]},"date_created":"2026-02-16T10:43:01Z","publication":"Encyclopedia of Astrophysics","abstract":[{"text":"Asteroseismology is the study of the interior physics and structure of stars using their pulsations. It is applicable to stars across the Hertzsprung–Russell (HR) diagram and a powerful technique not only to measure masses, radii, and ages but also directly constrain interior rotation, chemical mixing, and magnetism. This is because a star's self-excited pulsation modes are sensitive to its structure. Asteroseismology generally requires long-duration and high-precision time-series data. The method of forward asteroseismic modeling, which is the statistical comparison of observed pulsation mode frequencies to theoretically predicted pulsation frequencies calculated from a grid of models, provides precise constraints for calibrating various transport phenomena. In this introduction to asteroseismology, we provide an overview of its principles, and the typical data sets and methodologies used to constrain stellar interiors. Finally, we present key highlights of asteroseismic results from across the HR diagram, and conclude with ongoing challenges and future prospects for this ever-expanding field within stellar astrophysics.","lang":"eng"}],"date_updated":"2026-02-17T11:05:20Z","type":"book_chapter","OA_type":"green","title":"Asteroseismology","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"repository","oa":1,"citation":{"apa":"Bowman, D. M., &#38; Bugnet, L. A. (2026). Asteroseismology. In I. Mandel (Ed.), <i>Encyclopedia of Astrophysics</i> (Vol. 2, pp. 133–153). Elsevier. <a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">https://doi.org/10.1016/b978-0-443-21439-4.00036-5</a>","ama":"Bowman DM, Bugnet LA. Asteroseismology. In: Mandel I, ed. <i>Encyclopedia of Astrophysics</i>. Vol 2. Elsevier; 2026:133-153. doi:<a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">10.1016/b978-0-443-21439-4.00036-5</a>","ieee":"D. M. Bowman and L. A. Bugnet, “Asteroseismology,” in <i>Encyclopedia of Astrophysics</i>, vol. 2, I. Mandel, Ed. Elsevier, 2026, pp. 133–153.","ista":"Bowman DM, Bugnet LA. 2026.Asteroseismology. In: Encyclopedia of Astrophysics. vol. 2, 133–153.","short":"D.M. Bowman, L.A. Bugnet, in:, I. Mandel (Ed.), Encyclopedia of Astrophysics, Elsevier, 2026, pp. 133–153.","chicago":"Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” In <i>Encyclopedia of Astrophysics</i>, edited by Ilya Mandel, 2:133–53. Elsevier, 2026. <a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">https://doi.org/10.1016/b978-0-443-21439-4.00036-5</a>.","mla":"Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” <i>Encyclopedia of Astrophysics</i>, edited by Ilya Mandel, vol. 2, Elsevier, 2026, pp. 133–53, doi:<a href=\"https://doi.org/10.1016/b978-0-443-21439-4.00036-5\">10.1016/b978-0-443-21439-4.00036-5</a>."},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2410.01715","open_access":"1"}],"status":"public","scopus_import":"1","doi":"10.1016/b978-0-443-21439-4.00036-5","day":"01","department":[{"_id":"LiBu"}],"publication_status":"published","month":"01","quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Preprint","arxiv":1,"intvolume":"         2","volume":2,"_id":"21230","external_id":{"arxiv":["2410.01715"]},"author":[{"first_name":"Dominic M.","full_name":"Bowman, Dominic M.","last_name":"Bowman"},{"first_name":"Lisa Annabelle","orcid":"0000-0003-0142-4000","last_name":"Bugnet","id":"d9edb345-f866-11ec-9b37-d119b5234501","full_name":"Bugnet, Lisa Annabelle"}],"publisher":"Elsevier","year":"2026","date_published":"2026-01-01T00:00:00Z","editor":[{"last_name":"Mandel","full_name":"Mandel, Ilya","first_name":"Ilya"}],"page":"133-153","article_processing_charge":"No"},{"date_published":"2026-02-05T00:00:00Z","pmid":1,"article_processing_charge":"Yes (via OA deal)","publisher":"Springer Nature","ddc":["570"],"year":"2026","article_number":"20","_id":"21231","external_id":{"pmid":["41611727"]},"author":[{"last_name":"Arruda","full_name":"Arruda, Jonas","first_name":"Jonas"},{"last_name":"Alamoudi","full_name":"Alamoudi, Emad","first_name":"Emad"},{"first_name":"Robert","full_name":"Mueller, Robert","last_name":"Mueller"},{"full_name":"Vaisband, Marc","last_name":"Vaisband","first_name":"Marc"},{"first_name":"Ronja","last_name":"Molkenbur","full_name":"Molkenbur, Ronja"},{"last_name":"Merrin","id":"4515C308-F248-11E8-B48F-1D18A9856A87","full_name":"Merrin, Jack","first_name":"Jack","orcid":"0000-0001-5145-4609"},{"first_name":"Eva","full_name":"Kiermaier, Eva","last_name":"Kiermaier"},{"full_name":"Hasenauer, Jan","last_name":"Hasenauer","first_name":"Jan"}],"intvolume":"        12","volume":12,"month":"02","department":[{"_id":"NanoFab"}],"publication_status":"published","day":"05","doi":"10.1038/s41540-026-00648-9","language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Published Version","status":"public","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"file":[{"access_level":"open_access","success":1,"content_type":"application/pdf","checksum":"99b2e6bbaaedf45f22e07751948669f5","relation":"main_file","file_id":"21346","date_created":"2026-02-23T10:09:03Z","file_name":"2026_npjSysBioApp_Arruda.pdf","date_updated":"2026-02-23T10:09:03Z","creator":"dernst","file_size":10217687}],"citation":{"ama":"Arruda J, Alamoudi E, Mueller R, et al. Simulation-based inference of cell migration dynamics in complex spatial environments. <i>npj Systems Biology and Applications</i>. 2026;12. doi:<a href=\"https://doi.org/10.1038/s41540-026-00648-9\">10.1038/s41540-026-00648-9</a>","apa":"Arruda, J., Alamoudi, E., Mueller, R., Vaisband, M., Molkenbur, R., Merrin, J., … Hasenauer, J. (2026). Simulation-based inference of cell migration dynamics in complex spatial environments. <i>Npj Systems Biology and Applications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41540-026-00648-9\">https://doi.org/10.1038/s41540-026-00648-9</a>","ieee":"J. Arruda <i>et al.</i>, “Simulation-based inference of cell migration dynamics in complex spatial environments,” <i>npj Systems Biology and Applications</i>, vol. 12. Springer Nature, 2026.","ista":"Arruda J, Alamoudi E, Mueller R, Vaisband M, Molkenbur R, Merrin J, Kiermaier E, Hasenauer J. 2026. Simulation-based inference of cell migration dynamics in complex spatial environments. npj Systems Biology and Applications. 12, 20.","mla":"Arruda, Jonas, et al. “Simulation-Based Inference of Cell Migration Dynamics in Complex Spatial Environments.” <i>Npj Systems Biology and Applications</i>, vol. 12, 20, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41540-026-00648-9\">10.1038/s41540-026-00648-9</a>.","chicago":"Arruda, Jonas, Emad Alamoudi, Robert Mueller, Marc Vaisband, Ronja Molkenbur, Jack Merrin, Eva Kiermaier, and Jan Hasenauer. “Simulation-Based Inference of Cell Migration Dynamics in Complex Spatial Environments.” <i>Npj Systems Biology and Applications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41540-026-00648-9\">https://doi.org/10.1038/s41540-026-00648-9</a>.","short":"J. Arruda, E. Alamoudi, R. Mueller, M. Vaisband, R. Molkenbur, J. Merrin, E. Kiermaier, J. Hasenauer, Npj Systems Biology and Applications 12 (2026)."},"scopus_import":"1","acknowledgement":"This work was supported by the German Federal Ministry of Education and Research (BMBF) (EMUNE/031L0293C), the European Union via the ERC grant INTEGRATE, grant agreement number 101126146, and under Germany’s Excellence Strategy by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) (EXC 2047—390685813, EXC 2151—390873048, FOR5775 — 533863915, and 524747443), the University of Bonn via the Schlegel Professorship of J.H., and the returning experts fellowship of the Ministry of Innovation, Science, and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069). J.M. is a member of the Nanofabrication Facility and is supported by the Institute of Science and Technology Austria. E.K. acknowledges the TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments. The authors thank Laeschkir Würthner for his insightful comments on the implementation of the authors’ model. The views and opinions expressed are those of the authors only and do not necessarily reflect those of the funding agencies. Parts of Fig. 1 were created using BioRender. Open Access funding enabled and organized by Projekt DEAL.","article_type":"original","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Simulation-based inference of cell migration dynamics in complex spatial environments","OA_type":"gold","has_accepted_license":"1","oa":1,"abstract":[{"text":"To assess cell migration in complex spatial environments, microfabricated chips, such as mazes and pillar forests, are routinely used to impose spatial and mechanical constraints, and cell trajectories are followed within these structures by advanced imaging techniques. In systems mechanobiology, computational models serve as essential tools to uncover how physical geometry influences intracellular dynamics; however, decoding such complex behaviors requires advanced inference techniques. Here, we integrated experimental observations of dendritic cell migration in a geometrically constrained microenvironment into a Cellular Potts model. We demonstrated that these spatial constraints modulate the motility dynamics, including speed and directional changes. We show that classical summary statistics, such as mean squared displacement and turning angle distributions, can resolve key mechanistic features but fail to extract richer spatiotemporal patterns, limiting accurate parameter inference. To solve this, we applied neural posterior estimation with in-the-loop learning of summary features. This learned summary representation of the data enables robust and flexible parameter inference, providing a data-driven framework for model calibration and advancing quantitative analysis of cell migration in structured microenvironments.","lang":"eng"}],"publication":"npj Systems Biology and Applications","date_created":"2026-02-16T10:44:31Z","publication_identifier":{"eissn":["2056-7189"]},"PlanS_conform":"1","file_date_updated":"2026-02-23T10:09:03Z","type":"journal_article","DOAJ_listed":"1","date_updated":"2026-02-23T10:10:10Z"},{"intvolume":"         5","volume":5,"_id":"21232","external_id":{"arxiv":["2305.02724"]},"author":[{"last_name":"Bleile","full_name":"Bleile, Yossi","id":"920a7385-7995-11ef-9bfd-8c434cd8f3c2","orcid":"0000-0002-4861-9174","first_name":"Yossi"}],"publisher":"Springer Nature","ddc":["510"],"article_number":"17","year":"2026","date_published":"2026-02-08T00:00:00Z","article_processing_charge":"Yes (via OA deal)","abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title>\r\n                  <jats:p>In this paper, we consider a simple class of stratified spaces – 2-complexes. We present an algorithm that learns the abstract structure of an embedded 2-complex from a point cloud sampled from it. We use tools and inspiration from computational geometry, algebraic topology, and topological data analysis and prove the correctness of the identified abstract structure under assumptions on the embedding.</jats:p>"}],"publication_identifier":{"issn":["2730-9657"]},"date_created":"2026-02-16T10:44:44Z","publication":"La Matematica","PlanS_conform":"1","file_date_updated":"2026-02-23T10:18:52Z","date_updated":"2026-06-11T11:51:14Z","type":"journal_article","OA_place":"publisher","article_type":"original","OA_type":"hybrid","title":"Towards stratified space learning: 2-complexes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","oa":1,"status":"public","file":[{"date_updated":"2026-02-23T10:18:52Z","file_size":15051582,"creator":"dernst","date_created":"2026-02-23T10:18:52Z","file_id":"21347","file_name":"2026_LaMatematica_Bleile.pdf","content_type":"application/pdf","relation":"main_file","checksum":"6cae2efb47b025af22a8539c606a4e09","success":1,"access_level":"open_access"}],"citation":{"ista":"Bokor Bleile Y. 2026. Towards stratified space learning: 2-complexes. La Matematica. 5, 17.","short":"Y. Bokor Bleile, La Matematica 5 (2026).","chicago":"Bokor Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” <i>La Matematica</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s44007-025-00183-9\">https://doi.org/10.1007/s44007-025-00183-9</a>.","mla":"Bokor Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” <i>La Matematica</i>, vol. 5, 17, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s44007-025-00183-9\">10.1007/s44007-025-00183-9</a>.","ama":"Bokor Bleile Y. Towards stratified space learning: 2-complexes. <i>La Matematica</i>. 2026;5. doi:<a href=\"https://doi.org/10.1007/s44007-025-00183-9\">10.1007/s44007-025-00183-9</a>","apa":"Bokor Bleile, Y. (2026). Towards stratified space learning: 2-complexes. <i>La Matematica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s44007-025-00183-9\">https://doi.org/10.1007/s44007-025-00183-9</a>","ieee":"Y. Bokor Bleile, “Towards stratified space learning: 2-complexes,” <i>La Matematica</i>, vol. 5. Springer Nature, 2026."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"acknowledgement":"The author would like to thank Kate Turner, Chris Williams, Jonathan Spreer, Stephan Tillmann, Vanessa Robins, Vigleik Angeltveit, Martin Helmer, and James Morgan for very helpful discussions; and thanks Sara Kališnik Hintz and Paul Bendich for comments on an earlier version. Additonally, the author would like to thank both reviewers for their very insightful and helpful comments, without which the paper would be infinitely less coherent than it currently is. Open access funding provided by Institute of Science and Technology (IST Austria). The work in this paper was supported by an Australian Federal Government Grant, 2019-2022, Stratified Space Learning.","scopus_import":"1","month":"02","corr_author":"1","doi":"10.1007/s44007-025-00183-9","day":"08","department":[{"_id":"HeEd"}],"publication_status":"published","arxiv":1,"oa_version":"Published Version","quality_controlled":"1","language":[{"iso":"eng"}]},{"author":[{"last_name":"Yoon","full_name":"Yoon, Arim","first_name":"Arim"},{"first_name":"Cathy","last_name":"Hohenegger","full_name":"Hohenegger, Cathy"},{"full_name":"Bao, Jiawei","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","last_name":"Bao","first_name":"Jiawei"},{"first_name":"Lukas","full_name":"Brunner, Lukas","last_name":"Brunner"}],"issue":"1","_id":"21233","volume":17,"intvolume":"        17","article_processing_charge":"Yes (via OA deal)","page":"167-179","date_published":"2026-02-04T00:00:00Z","year":"2026","publisher":"Copernicus GmbH","ddc":["550"],"has_accepted_license":"1","oa":1,"OA_place":"publisher","article_type":"original","OA_type":"gold","title":"Extreme events in the Amazon after deforestation","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-02-23T10:26:29Z","PlanS_conform":"1","date_updated":"2026-02-23T10:28:48Z","DOAJ_listed":"1","type":"journal_article","abstract":[{"lang":"eng","text":"Potential self-perpetuating dieback of the Amazon rain forest has been a topic of concern. The concern is that initial deforestation could critically impair the forest’s water recycling capacities, further harming the remaining forest through reduced annual precipitation. Many studies have focused on annual mean precipitation changes, due to its widespread perception as a central control on the Amazon rain forest’s stability. However, the impact of deforestation goes beyond changes in the annual mean precipitation. Yet, global coarse-resolution climate models are not well suited to investigate changes in short-duration and localized events due to their coarse resolution. Here, we circumvent these issues by analyzing a full-deforestation scenario simulated by a global storm-resolving model. We focus on changes in the tail of the hourly distribution of precipitation, temperature, and wind. Hourly precipitation becomes more extreme in the absence of the forest than in an intact forest, with an increased occurrence of both no rain and intense rainfall. These changes are driven by enhanced moisture convergence that strengthens vertical velocity. On average, the near-surface temperature rises significantly by about 3.84 °C, and the daily minimum temperature after deforestation becomes similar to the daily maximum temperature before deforestation. Except for wet-bulb temperature, human heat stress indicators shift to more severe levels, with implications for health and a significant reduction in work productivity. Finally, the mean 10 m wind speed intensifies by a factor of four, with the 99th percentile wind speed doubling. To summarize, our findings, while based on an idealized case, provide a stark warning of the effects of continuing deforestation of the Amazon."}],"publication_identifier":{"eissn":["2190-4987"]},"publication":"Earth System Dynamics","date_created":"2026-02-16T10:44:58Z","language":[{"iso":"eng"}],"oa_version":"Published Version","quality_controlled":"1","month":"02","doi":"10.5194/esd-17-167-2026","day":"04","department":[{"_id":"CaMu"}],"publication_status":"published","acknowledgement":"AY acknowledges funding by the CLICCS centre of excellence subproject A3 funded by DFG. We thank the German Climate Computing Center DKRZ for providing computing resources and the Integrated Climate Data Center (ICDC), the Center for Earth System Research and Sustainability (CEN), University of Hamburg, for supporting the IMERG data. In addition, we would like to thank Jana Sillmann for suggesting the analysis of heat stress indices and Keno Riechers for providing a thorough internal review of the initial manuscript at the Max Planck Institute for Meteorology. Open Access funding is enabled and organized by Projekt DEAL. This research has been supported by the Deutsche Forschungsgemeinschaft (grant no. CLICCS 390683824 (A3)). The article processing charges for this open-access publication were covered by the Max Planck Society.","scopus_import":"1","status":"public","file":[{"access_level":"open_access","success":1,"content_type":"application/pdf","checksum":"6c3669c463731ad7c484b2990eb8ee0d","relation":"main_file","date_created":"2026-02-23T10:26:29Z","file_id":"21348","file_name":"2026_EarthSystDynam_Yoon.pdf","date_updated":"2026-02-23T10:26:29Z","creator":"dernst","file_size":2068229}],"citation":{"short":"A. Yoon, C. Hohenegger, J. Bao, L. Brunner, Earth System Dynamics 17 (2026) 167–179.","mla":"Yoon, Arim, et al. “Extreme Events in the Amazon after Deforestation.” <i>Earth System Dynamics</i>, vol. 17, no. 1, Copernicus GmbH, 2026, pp. 167–79, doi:<a href=\"https://doi.org/10.5194/esd-17-167-2026\">10.5194/esd-17-167-2026</a>.","chicago":"Yoon, Arim, Cathy Hohenegger, Jiawei Bao, and Lukas Brunner. “Extreme Events in the Amazon after Deforestation.” <i>Earth System Dynamics</i>. Copernicus GmbH, 2026. <a href=\"https://doi.org/10.5194/esd-17-167-2026\">https://doi.org/10.5194/esd-17-167-2026</a>.","ista":"Yoon A, Hohenegger C, Bao J, Brunner L. 2026. Extreme events in the Amazon after deforestation. Earth System Dynamics. 17(1), 167–179.","ieee":"A. Yoon, C. Hohenegger, J. Bao, and L. Brunner, “Extreme events in the Amazon after deforestation,” <i>Earth System Dynamics</i>, vol. 17, no. 1. Copernicus GmbH, pp. 167–179, 2026.","ama":"Yoon A, Hohenegger C, Bao J, Brunner L. Extreme events in the Amazon after deforestation. <i>Earth System Dynamics</i>. 2026;17(1):167-179. doi:<a href=\"https://doi.org/10.5194/esd-17-167-2026\">10.5194/esd-17-167-2026</a>","apa":"Yoon, A., Hohenegger, C., Bao, J., &#38; Brunner, L. (2026). Extreme events in the Amazon after deforestation. <i>Earth System Dynamics</i>. Copernicus GmbH. <a href=\"https://doi.org/10.5194/esd-17-167-2026\">https://doi.org/10.5194/esd-17-167-2026</a>"},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"}},{"date_created":"2026-02-16T10:45:10Z","publication":"Cell Systems","publication_identifier":{"issn":["2405-4712"]},"abstract":[{"text":"In aged humans and mice, hypobranched glycogen aggregates, known as polyglucosan bodies (PGBs), accumulate in hippocampal astrocytes. While PGBs are linked to cognitive decline in neurological diseases, they remain largely unstudied in the context of typical aging. We show that PGBs arise in autophagy-dysregulated astrocytes in the aged hippocampus, with substantial variation among 32 inbred BXD mouse strains. Genetic mapping through quantitative trait locus analysis identified a major locus (Pgb1) that modulates hippocampal PGB burden. Extensive transcriptomic and proteomic datasets were produced for the aged hippocampus of the BXD family to investigate the mechanism by which the Pgb1 locus modulates PGB burden. We identified that Pgb1 contains allelic Smarcal1 and Usp37 variants and influences PGB burden through trans-regulation of mRNA and protein expression levels, including abundance of glycogen-mobilizing factor PYGB. Furthermore, comprehensive phenome-wide association scans, transcriptomic analyses, and direct behavioral testing demonstrated that cognition remains intact despite age-related PGB burden. A record of this paper’s transparent peer review process is included in the supplemental information.","lang":"eng"}],"type":"journal_article","date_updated":"2026-02-23T10:35:01Z","file_date_updated":"2026-02-23T10:32:12Z","PlanS_conform":"1","title":"The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","article_type":"original","OA_place":"publisher","oa":1,"has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"citation":{"ista":"Gómez-Pascual A, Glikman DM, Ng HX, Tomkins JE, Lu L, Xu Y, Ashbrook DG, Kaczorowski C, Kempermann G, Killmar J, Mozhui K, Ohlenschläger O, Aebersold R, Ingram DK, Williams EG, Jucker M, Overall RW, Williams RW, de Bakker DEM. 2026. The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. Cell Systems. 17(2), 101488.","chicago":"Gómez-Pascual, Alicia, Dow M Glikman, Hui Xin Ng, James E. Tomkins, Lu Lu, Ying Xu, David G. Ashbrook, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen Aggregation in Astrocytes of the Aged Hippocampus.” <i>Cell Systems</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cels.2025.101488\">https://doi.org/10.1016/j.cels.2025.101488</a>.","mla":"Gómez-Pascual, Alicia, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen Aggregation in Astrocytes of the Aged Hippocampus.” <i>Cell Systems</i>, vol. 17, no. 2, 101488, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.cels.2025.101488\">10.1016/j.cels.2025.101488</a>.","short":"A. Gómez-Pascual, D.M. Glikman, H.X. Ng, J.E. Tomkins, L. Lu, Y. Xu, D.G. Ashbrook, C. Kaczorowski, G. Kempermann, J. Killmar, K. Mozhui, O. Ohlenschläger, R. Aebersold, D.K. Ingram, E.G. Williams, M. Jucker, R.W. Overall, R.W. Williams, D.E.M. de Bakker, Cell Systems 17 (2026).","apa":"Gómez-Pascual, A., Glikman, D. M., Ng, H. X., Tomkins, J. E., Lu, L., Xu, Y., … de Bakker, D. E. M. (2026). The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. <i>Cell Systems</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cels.2025.101488\">https://doi.org/10.1016/j.cels.2025.101488</a>","ama":"Gómez-Pascual A, Glikman DM, Ng HX, et al. The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. <i>Cell Systems</i>. 2026;17(2). doi:<a href=\"https://doi.org/10.1016/j.cels.2025.101488\">10.1016/j.cels.2025.101488</a>","ieee":"A. Gómez-Pascual <i>et al.</i>, “The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus,” <i>Cell Systems</i>, vol. 17, no. 2. Elsevier, 2026."},"file":[{"checksum":"920e8edfd3b8b42f5bb6f86d4c66c54d","relation":"main_file","content_type":"application/pdf","access_level":"open_access","success":1,"creator":"dernst","file_size":10606778,"date_updated":"2026-02-23T10:32:12Z","file_name":"2026_CellSystems_GomezPascual.pdf","file_id":"21349","date_created":"2026-02-23T10:32:12Z"}],"status":"public","scopus_import":"1","acknowledgement":"We would like to thank the Summer School Systems Genetics of Neural Ageing for bringing us together and spurring our international collaboration. We would also like to acknowledge the funding for the Summer School 2022 from the e:Med Systems Medicine Program of the BMBF (Bundesministerium für Bildung und Forschung; German Ministry of Education and Research) to R.W.O. In addition, we would like to thank the FLI imaging core facility for their assistance. A.G.-P. is supported by Fundación Séneca, Región de Murcia, Spain (21259/FPI/19). D.E.M.d.B. is financed by a Rubicon scholarship (452021116) from the Dutch Research Council (NWO). This work was also supported by NIH NIA R01AG070913-01 (R.W.W.), R01AG075813-01 (D.G.A.), and R01AG075818 (C.K.). We acknowledge the help of Larry Mobraaten (Jackson Laboratory, Bar Harbor, MN) with the BXD strains and U. Obermüller for the help with the histology. For the purpose of open access, the authors have applied a CC BY public copyright license to all author-accepted manuscripts arising from this submission.","department":[{"_id":"GradSch"}],"publication_status":"published","doi":"10.1016/j.cels.2025.101488","day":"18","month":"02","language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Published Version","intvolume":"        17","volume":17,"_id":"21234","external_id":{"pmid":["41633365"]},"issue":"2","author":[{"last_name":"Gómez-Pascual","full_name":"Gómez-Pascual, Alicia","first_name":"Alicia"},{"full_name":"Glikman, Dow M","id":"ab8acda1-91c1-11f0-aad8-f75d3d6424d8","last_name":"Glikman","first_name":"Dow M"},{"first_name":"Hui Xin","last_name":"Ng","full_name":"Ng, Hui Xin"},{"first_name":"James E.","full_name":"Tomkins, James E.","last_name":"Tomkins"},{"first_name":"Lu","full_name":"Lu, Lu","last_name":"Lu"},{"last_name":"Xu","full_name":"Xu, Ying","first_name":"Ying"},{"first_name":"David G.","last_name":"Ashbrook","full_name":"Ashbrook, David G."},{"first_name":"Catherine","full_name":"Kaczorowski, Catherine","last_name":"Kaczorowski"},{"last_name":"Kempermann","full_name":"Kempermann, Gerd","first_name":"Gerd"},{"first_name":"John","last_name":"Killmar","full_name":"Killmar, John"},{"first_name":"Khyobeni","last_name":"Mozhui","full_name":"Mozhui, Khyobeni"},{"last_name":"Ohlenschläger","full_name":"Ohlenschläger, Oliver","first_name":"Oliver"},{"full_name":"Aebersold, Rudolf","last_name":"Aebersold","first_name":"Rudolf"},{"first_name":"Donald K.","last_name":"Ingram","full_name":"Ingram, Donald K."},{"first_name":"Evan G.","full_name":"Williams, Evan G.","last_name":"Williams"},{"first_name":"Mathias","last_name":"Jucker","full_name":"Jucker, Mathias"},{"first_name":"Rupert W.","full_name":"Overall, Rupert W.","last_name":"Overall"},{"last_name":"Williams","full_name":"Williams, Robert W.","first_name":"Robert W."},{"full_name":"de Bakker, Dennis E.M.","last_name":"de Bakker","first_name":"Dennis E.M."}],"ddc":["570"],"publisher":"Elsevier","year":"2026","article_number":"101488","pmid":1,"date_published":"2026-02-18T00:00:00Z","article_processing_charge":"No"},{"month":"01","department":[{"_id":"TiBr"}],"publication_status":"published","doi":"10.2140/pjm.2026.340.179","day":"01","arxiv":1,"language":[{"iso":"eng"}],"oa_version":"Preprint","quality_controlled":"1","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2406.09256"}],"citation":{"ama":"Rome N, Yamagishi S. Integral solutions to systems of diagonal equations. <i>Pacific Journal of Mathematics</i>. 2026;340(1):179-198. doi:<a href=\"https://doi.org/10.2140/pjm.2026.340.179\">10.2140/pjm.2026.340.179</a>","apa":"Rome, N., &#38; Yamagishi, S. (2026). Integral solutions to systems of diagonal equations. <i>Pacific Journal of Mathematics</i>. Mathematical Sciences Publishers. <a href=\"https://doi.org/10.2140/pjm.2026.340.179\">https://doi.org/10.2140/pjm.2026.340.179</a>","ieee":"N. Rome and S. Yamagishi, “Integral solutions to systems of diagonal equations,” <i>Pacific Journal of Mathematics</i>, vol. 340, no. 1. Mathematical Sciences Publishers, pp. 179–198, 2026.","ista":"Rome N, Yamagishi S. 2026. Integral solutions to systems of diagonal equations. Pacific Journal of Mathematics. 340(1), 179–198.","mla":"Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal Equations.” <i>Pacific Journal of Mathematics</i>, vol. 340, no. 1, Mathematical Sciences Publishers, 2026, pp. 179–98, doi:<a href=\"https://doi.org/10.2140/pjm.2026.340.179\">10.2140/pjm.2026.340.179</a>.","chicago":"Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal Equations.” <i>Pacific Journal of Mathematics</i>. Mathematical Sciences Publishers, 2026. <a href=\"https://doi.org/10.2140/pjm.2026.340.179\">https://doi.org/10.2140/pjm.2026.340.179</a>.","short":"N. Rome, S. Yamagishi, Pacific Journal of Mathematics 340 (2026) 179–198."},"article_type":"original","OA_place":"repository","title":"Integral solutions to systems of diagonal equations","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"green","oa":1,"abstract":[{"text":"We obtain an asymptotic formula for the number of integral solutions to a system of diagonal equations. We obtain an asymptotic formula for the number of solutions with variables restricted to smooth numbers as well. We improve the required number of variables compared to previous results by incorporating recent progress on Waring’s problem and the resolution of the main conjecture in Vinogradov’s mean value theorem.","lang":"eng"}],"publication":"Pacific Journal of Mathematics","date_created":"2026-02-16T15:17:27Z","publication_identifier":{"issn":["0030-8730"],"eissn":["1945-5844"]},"type":"journal_article","date_updated":"2026-02-17T11:43:14Z","date_published":"2026-01-01T00:00:00Z","article_processing_charge":"No","page":"179-198","publisher":"Mathematical Sciences Publishers","year":"2026","_id":"21242","issue":"1","external_id":{"arxiv":["2406.09256"]},"author":[{"first_name":"Nick","full_name":"Rome, Nick","last_name":"Rome"},{"full_name":"Yamagishi, Shuntaro","id":"0c3fbc5c-f7a6-11ec-8d70-9485e75b416b","last_name":"Yamagishi","first_name":"Shuntaro"}],"intvolume":"       340","volume":340},{"intvolume":"        11","volume":11,"issue":"1","_id":"21273","external_id":{"arxiv":["2512.11368"]},"author":[{"full_name":"Dombret, Albert","last_name":"Dombret","first_name":"Albert"},{"full_name":"Sutter, Adrien","last_name":"Sutter","first_name":"Adrien"},{"full_name":"Coquinot, Baptiste","id":"f8417bd4-f599-11ee-a482-b927e3ed1e8e","last_name":"Coquinot","orcid":"0000-0001-5524-596X","first_name":"Baptiste"},{"first_name":"Nikita","last_name":"Kavokine","full_name":"Kavokine, Nikita"},{"first_name":"Benoit","full_name":"Coasne, Benoit","last_name":"Coasne"},{"last_name":"Bocquet","full_name":"Bocquet, Lydéric","first_name":"Lydéric"}],"publisher":"American Physical Society","article_number":"014201","year":"2026","date_published":"2026-01-21T00:00:00Z","article_processing_charge":"No","publication_identifier":{"eissn":["2469-990X"]},"publication":"Physical Review Fluids","date_created":"2026-02-17T08:10:09Z","abstract":[{"text":"In this paper we examine how porosity fluctuations affect the hydrodynamic permeability of a porous matrix or membrane. We introduce a fluctuating Darcy model, which couples the Navier-Stokes equation to the space- and time-dependent porosity fluctuations via a Darcy friction term. Using a perturbative approach, a Dyson equation for hydrodynamic fluctuations is derived and solved to express the permeability in terms of the matrix fluctuation spectrum. Surprisingly, the model reveals strong modifications of the fluid permeability in fluctuating matrices compared to static ones. Applications to various matrix excitation models, the breathing matrix, phonons, and active forcing, highlight the significant influence of matrix fluctuations on fluid transport, offering insights for optimizing membrane design for separation applications.","lang":"eng"}],"date_updated":"2026-02-23T12:01:57Z","type":"journal_article","OA_type":"green","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Hydrodynamic permeability of fluctuating porous membranes","OA_place":"repository","article_type":"original","oa":1,"citation":{"ama":"Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. Hydrodynamic permeability of fluctuating porous membranes. <i>Physical Review Fluids</i>. 2026;11(1). doi:<a href=\"https://doi.org/10.1103/m8h6-1wfk\">10.1103/m8h6-1wfk</a>","apa":"Dombret, A., Sutter, A., Coquinot, B., Kavokine, N., Coasne, B., &#38; Bocquet, L. (2026). Hydrodynamic permeability of fluctuating porous membranes. <i>Physical Review Fluids</i>. American Physical Society. <a href=\"https://doi.org/10.1103/m8h6-1wfk\">https://doi.org/10.1103/m8h6-1wfk</a>","ieee":"A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, and L. Bocquet, “Hydrodynamic permeability of fluctuating porous membranes,” <i>Physical Review Fluids</i>, vol. 11, no. 1. American Physical Society, 2026.","ista":"Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. 2026. Hydrodynamic permeability of fluctuating porous membranes. Physical Review Fluids. 11(1), 014201.","mla":"Dombret, Albert, et al. “Hydrodynamic Permeability of Fluctuating Porous Membranes.” <i>Physical Review Fluids</i>, vol. 11, no. 1, 014201, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/m8h6-1wfk\">10.1103/m8h6-1wfk</a>.","short":"A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, L. Bocquet, Physical Review Fluids 11 (2026).","chicago":"Dombret, Albert, Adrien Sutter, Baptiste Coquinot, Nikita Kavokine, Benoit Coasne, and Lydéric Bocquet. “Hydrodynamic Permeability of Fluctuating Porous Membranes.” <i>Physical Review Fluids</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/m8h6-1wfk\">https://doi.org/10.1103/m8h6-1wfk</a>."},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2512.11368","open_access":"1"}],"status":"public","acknowledgement":"The authors acknowledge support from ERC project n-AQUA, Grant Agreement No. 101071937.\r\nB.C. and A.S. acknowledge support from the CFM Foundation. B.C. acknowledges support from\r\nthe NOMIS Foundation.","doi":"10.1103/m8h6-1wfk","day":"21","publication_status":"published","department":[{"_id":"MiLe"}],"corr_author":"1","month":"01","oa_version":"Preprint","quality_controlled":"1","language":[{"iso":"eng"}],"arxiv":1},{"volume":706,"intvolume":"       706","author":[{"first_name":"Andrei-Alexandru","id":"4d500bea-31f8-11ee-a48d-d4904fb363c7","full_name":"Cristea, Andrei-Alexandru","last_name":"Cristea"},{"last_name":"Caiazzo","full_name":"Caiazzo, Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","first_name":"Ilaria"},{"first_name":"Tim","last_name":"Cunningham","full_name":"Cunningham, Tim"},{"first_name":"John C.","full_name":"Raymond, John C.","last_name":"Raymond"},{"full_name":"Vennes, Stephane","last_name":"Vennes","first_name":"Stephane"},{"full_name":"Kawka, Adela","last_name":"Kawka","first_name":"Adela"},{"id":"502cfd30-32c1-11ee-a9a4-d8dad5c6739e","full_name":"Desai, Aayush A","last_name":"Desai","first_name":"Aayush A"},{"last_name":"Miller","full_name":"Miller, David R.","first_name":"David R."},{"last_name":"Hermes","full_name":"Hermes, J. J.","first_name":"J. J."},{"first_name":"Jim","last_name":"Fuller","full_name":"Fuller, Jim"},{"first_name":"Jeremy","full_name":"Heyl, Jeremy","last_name":"Heyl"},{"full_name":"van Roestel, Jan","last_name":"van Roestel","first_name":"Jan"},{"first_name":"Kevin B.","last_name":"Burdge","full_name":"Burdge, Kevin B."},{"first_name":"Antonio C.","full_name":"Rodriguez, Antonio C.","last_name":"Rodriguez"},{"last_name":"Pelisoli","full_name":"Pelisoli, Ingrid","first_name":"Ingrid"},{"first_name":"Boris T.","full_name":"Gänsicke, Boris T.","last_name":"Gänsicke"},{"first_name":"Paula","last_name":"Szkody","full_name":"Szkody, Paula"},{"last_name":"Kenyon","full_name":"Kenyon, Scott J.","first_name":"Scott J."},{"first_name":"Zach","full_name":"Vanderbosch, Zach","last_name":"Vanderbosch"},{"full_name":"Drake, Andrew","last_name":"Drake","first_name":"Andrew"},{"first_name":"Lilia","full_name":"Ferrario, Lilia","last_name":"Ferrario"},{"full_name":"Wickramasinghe, Dayal","last_name":"Wickramasinghe","first_name":"Dayal"},{"full_name":"Karambelkar, Viraj R.","last_name":"Karambelkar","first_name":"Viraj R."},{"first_name":"Stephen","full_name":"Justham, Stephen","last_name":"Justham"},{"full_name":"Pakmor, Ruediger","last_name":"Pakmor","first_name":"Ruediger"},{"first_name":"Kareem","last_name":"El-Badry","full_name":"El-Badry, Kareem"},{"last_name":"Prince","full_name":"Prince, Thomas","first_name":"Thomas"},{"first_name":"S. R.","full_name":"Kulkarni, S. R.","last_name":"Kulkarni"},{"first_name":"Matthew J.","last_name":"Graham","full_name":"Graham, Matthew J."},{"full_name":"Masci, Frank J.","last_name":"Masci","first_name":"Frank J."},{"full_name":"Groom, Steven L.","last_name":"Groom","first_name":"Steven L."},{"first_name":"Josiah","full_name":"Purdum, Josiah","last_name":"Purdum"},{"first_name":"Richard","last_name":"Dekany","full_name":"Dekany, Richard"},{"first_name":"Eric C.","last_name":"Bellm","full_name":"Bellm, Eric C."}],"_id":"21274","year":"2026","article_number":"A188","publisher":"EDP Sciences","ddc":["520"],"article_processing_charge":"Yes","date_published":"2026-02-10T00:00:00Z","PlanS_conform":"1","file_date_updated":"2026-02-23T12:04:37Z","DOAJ_listed":"1","type":"journal_article","date_updated":"2026-04-28T12:01:21Z","abstract":[{"lang":"eng","text":"Many white dwarfs are observed in compact double white dwarf binaries, and through the emission of gravitational waves, a large fraction are destined to merge. The merger remnants that do not explode in a Type Ia supernova are expected to initially be rapidly rotating and highly magnetized. In this work, we present our discovery of the variable white dwarf ZTF J200832.79+444939.67, hereafter ZTF J2008+4449, as a likely merger remnant showing signs of circumstellar material without a stellar or substellar companion. The nature of ZTF J2008+4449 as a merger remnant is supported by its physical properties: it is hot (35 500 ± 300 K) and massive (1.12 ± 0.03 M\r\n                    <jats:sub>⊙</jats:sub>\r\n                    ), rapidly rotating with a period of ≈6.6 minutes, and likely possesses exceptionally strong magnetic fields (∼400−600 MG) at its surface. Remarkably, we detect a significant period derivative of (1.80 ± 0.09)×10\r\n                    <jats:sup>−12</jats:sup>\r\n                    s/s, indicating that the white dwarf is spinning down, and a soft X-ray emission that is inconsistent with photospheric emission. As the presence of a mass-transferring stellar or brown dwarf companion is excluded by infrared photometry, the detected spin-down and X-ray emission could be tell-tale signs of a magnetically driven wind or of interaction with circumstellar material, possibly originating from the fallback of gravitationally bound merger ejecta or from the tidal disruption of a planetary object. We also detect Balmer emission, which requires the presence of ionized hydrogen in the vicinity of the white dwarf, showing Doppler shifts as high as ≈2000 km s\r\n                    <jats:sup>−1</jats:sup>\r\n                    . The unusual variability of the Balmer emission on the spin period of the white dwarf is consistent with the trapping of a half ring of ionized gas in the magnetosphere of the white dwarf.\r\n                  </jats:p>"}],"date_created":"2026-02-17T08:12:05Z","publication":"Astronomy & Astrophysics","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"oa":1,"has_accepted_license":"1","article_type":"original","OA_place":"publisher","title":"A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_type":"gold","acknowledgement":"We thank Lynne Hillenbrand and Soumyadeep Bhattacharjee for helpful discussions, and Kishalay De for his help with the WIRC\r\nreduction pipeline. IC was supported by NASA through grants from the Space\r\nTelescope Science Institute, under NASA contracts NASA.22K1813, NAS5-\r\n26555 and NAS5-03127. TC was supported by NASA through the NASA Hubble\r\nFellowship grant HST-HF2-51527.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research\r\nin Astronomy, Inc., for NASA, under contract NAS5-26555. This project has\r\nreceived funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101020057). This work was based on observations obtained with the\r\nSamuel Oschin Telescope 48-inch and the 60-inch Telescope at the Palomar\r\nObservatory as part of the Zwicky Transient Facility project. ZTF is supported\r\nby the National Science Foundation under Grants No. AST-1440341, AST2034437, and currently Award #2407588. ZTF receives additional funding from\r\nthe ZTF partnership. Current members include Caltech, USA; Caltech/IPAC,\r\nUSA; University of Maryland, USA; University of California, Berkeley, USA;\r\nUniversity of Wisconsin at Milwaukee, USA; Cornell University, USA; Drexel\r\nUniversity, USA; University of North Carolina at Chapel Hill, USA; Institute\r\nof Science and Technology, Austria; National Central University, Taiwan, and\r\nOKC, University of Stockholm, Sweden. Operations are conducted by Caltech’s\r\nOptical Observatory (COO), Caltech/IPAC, and the University of Washington at\r\nSeattle, USA. This work has made use of data from the European Space Agency\r\n(ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by\r\nthe Gaia Data Processing and Analysis Consortium (DPAC, https://www.\r\ncosmos.esa.int/web/gaia/dpac/consortium). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. The Pan-STARRS1 Surveys (PS1)\r\nand the PS1 public science archive have been made possible through contributions by the Institute for Astronomy, the University of Hawaii, the PanSTARRS Project Office, the Max-Planck Society and its participating institutes, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck\r\nInstitute for Extraterrestrial Physics, Garching, The Johns Hopkins University,\r\nDurham University, the University of Edinburgh, the Queen’s University Belfast,\r\nthe Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated, the National Central University of Taiwan, the Space Telescope Science Institute, the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued through\r\nthe Planetary Science Division of the NASA Science Mission Directorate, the\r\nNational Science Foundation Grant No. AST–1238877, the University of Maryland, Eotvos Lorand University (ELTE), the Los Alamos National Laboratory,\r\nand the Gordon and Betty Moore Foundation. This work made use of Astropy\r\n(http://www.astropy.org): a community-developed core Python package\r\nand an ecosystem of tools and resources for astronomy (Astropy Collaboration\r\n2013, 2018, 2022).","status":"public","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"citation":{"chicago":"Cristea, Andrei-Alexandru, Ilaria Caiazzo, Tim Cunningham, John C. Raymond, Stephane Vennes, Adela Kawka, Aayush A Desai, et al. “A Half Ring of Ionized Circumstellar Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556432\">https://doi.org/10.1051/0004-6361/202556432</a>.","short":"A.-A. Cristea, I. Caiazzo, T. Cunningham, J.C. Raymond, S. Vennes, A. Kawka, A.A. Desai, D.R. Miller, J.J. Hermes, J. Fuller, J. Heyl, J. van Roestel, K.B. Burdge, A.C. Rodriguez, I. Pelisoli, B.T. Gänsicke, P. Szkody, S.J. Kenyon, Z. Vanderbosch, A. Drake, L. Ferrario, D. Wickramasinghe, V.R. Karambelkar, S. Justham, R. Pakmor, K. El-Badry, T. Prince, S.R. Kulkarni, M.J. Graham, F.J. Masci, S.L. Groom, J. Purdum, R. Dekany, E.C. Bellm, Astronomy &#38; Astrophysics 706 (2026).","mla":"Cristea, Andrei-Alexandru, et al. “A Half Ring of Ionized Circumstellar Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy &#38; Astrophysics</i>, vol. 706, A188, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556432\">10.1051/0004-6361/202556432</a>.","ista":"Cristea A-A, Caiazzo I, Cunningham T, Raymond JC, Vennes S, Kawka A, Desai AA, Miller DR, Hermes JJ, Fuller J, Heyl J, van Roestel J, Burdge KB, Rodriguez AC, Pelisoli I, Gänsicke BT, Szkody P, Kenyon SJ, Vanderbosch Z, Drake A, Ferrario L, Wickramasinghe D, Karambelkar VR, Justham S, Pakmor R, El-Badry K, Prince T, Kulkarni SR, Graham MJ, Masci FJ, Groom SL, Purdum J, Dekany R, Bellm EC. 2026. A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. Astronomy &#38; Astrophysics. 706, A188.","ieee":"A.-A. Cristea <i>et al.</i>, “A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant,” <i>Astronomy &#38; Astrophysics</i>, vol. 706. EDP Sciences, 2026.","apa":"Cristea, A.-A., Caiazzo, I., Cunningham, T., Raymond, J. C., Vennes, S., Kawka, A., … Bellm, E. C. (2026). A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556432\">https://doi.org/10.1051/0004-6361/202556432</a>","ama":"Cristea A-A, Caiazzo I, Cunningham T, et al. A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. <i>Astronomy &#38; Astrophysics</i>. 2026;706. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556432\">10.1051/0004-6361/202556432</a>"},"file":[{"date_created":"2026-02-23T12:04:37Z","file_id":"21350","file_name":"2026_AstronomyAstrophysics_Cristea.pdf","date_updated":"2026-02-23T12:04:37Z","creator":"dernst","file_size":5352853,"access_level":"open_access","success":1,"content_type":"application/pdf","checksum":"229b688e6e78cab5bb8e2bac366d1575","relation":"main_file"}],"language":[{"iso":"eng"}],"quality_controlled":"1","oa_version":"Published Version","related_material":{"link":[{"relation":"press_release","url":"https://ista.ac.at/en/news/twos-company-new-class-of-star-remnants/","description":"News on ISTA website"}]},"month":"02","corr_author":"1","department":[{"_id":"IlCa"},{"_id":"GradSch"}],"publication_status":"published","day":"10","doi":"10.1051/0004-6361/202556432"},{"status":"public","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"file":[{"file_name":"2026_PRXLife_Olmeda.pdf","date_created":"2026-02-24T06:53:05Z","file_id":"21351","file_size":5857833,"creator":"dernst","date_updated":"2026-02-24T06:53:05Z","success":1,"access_level":"open_access","relation":"main_file","checksum":"df9776422862d1d02c66d98e2d620849","content_type":"application/pdf"}],"citation":{"ieee":"F. Olmeda, M. Gupta, O. Bektas, and S. Rulands, “Spatiotemporal patterns of active epigenetic turnover,” <i>PRX Life</i>, vol. 4. American Physical Society, 2026.","apa":"Olmeda, F., Gupta, M., Bektas, O., &#38; Rulands, S. (2026). Spatiotemporal patterns of active epigenetic turnover. <i>PRX Life</i>. American Physical Society. <a href=\"https://doi.org/10.1103/89bj-79g5\">https://doi.org/10.1103/89bj-79g5</a>","ama":"Olmeda F, Gupta M, Bektas O, Rulands S. Spatiotemporal patterns of active epigenetic turnover. <i>PRX Life</i>. 2026;4. doi:<a href=\"https://doi.org/10.1103/89bj-79g5\">10.1103/89bj-79g5</a>","chicago":"Olmeda, Fabrizio, Misha Gupta, Onurcan Bektas, and Steffen Rulands. “Spatiotemporal Patterns of Active Epigenetic Turnover.” <i>PRX Life</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/89bj-79g5\">https://doi.org/10.1103/89bj-79g5</a>.","mla":"Olmeda, Fabrizio, et al. “Spatiotemporal Patterns of Active Epigenetic Turnover.” <i>PRX Life</i>, vol. 4, 013018, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/89bj-79g5\">10.1103/89bj-79g5</a>.","short":"F. Olmeda, M. Gupta, O. Bektas, S. Rulands, PRX Life 4 (2026).","ista":"Olmeda F, Gupta M, Bektas O, Rulands S. 2026. Spatiotemporal patterns of active epigenetic turnover. PRX Life. 4, 013018."},"acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 950349 and the Marie Skłodowska-Curie Grant Agreement No. 101034413. The computations in this paper were run in part on the the FASRC Cannon cluster supported by the FAS Division of Science Research Computing Group at Harvard University and the cluster of the Max Planck Institute for the Physics of Complex Systems.","month":"02","corr_author":"1","department":[{"_id":"EdHa"}],"publication_status":"published","ec_funded":1,"day":"09","doi":"10.1103/89bj-79g5","oa_version":"Published Version","quality_controlled":"1","language":[{"iso":"eng"}],"abstract":[{"text":"DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives rise to a biochemical cycle and active turnover of DNA methylation. While the ensuing biochemical oscillations have been implicated in the regulation of cell differentiation, their functional role and spatiotemporal dynamics are unknown. In this work, we demonstrate that chromatin-mediated coupling between these local biochemical cycles can lead to the emergence of phase-locked domains, regions of locally synchronized turnover activity, whose coarsening is arrested by genomic heterogeneity. We introduce a minimal model based on stochastic oscillators with constrained long-range and nonreciprocal interactions, shaped by the local chromatin organization. Through a combination of analytical theory and stochastic simulations, we predict both the degree of synchronization and the typical size of emergent phase-locked domains. We qualitatively test these predictions using single-cell sequencing data. Our results show that DNA methylation turnover exhibits surprisingly rich spatiotemporal patterns that may be used by cells to control cell differentiation.","lang":"eng"}],"date_created":"2026-02-17T08:17:53Z","publication":"PRX Life","publication_identifier":{"eissn":["2835-8279"]},"PlanS_conform":"1","file_date_updated":"2026-02-24T06:53:05Z","type":"journal_article","DOAJ_listed":"1","date_updated":"2026-02-24T06:54:32Z","article_type":"original","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Spatiotemporal patterns of active epigenetic turnover","OA_type":"gold","oa":1,"has_accepted_license":"1","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"publisher":"American Physical Society","ddc":["570"],"year":"2026","article_number":"013018","date_published":"2026-02-09T00:00:00Z","article_processing_charge":"Yes","intvolume":"         4","volume":4,"_id":"21275","author":[{"first_name":"Fabrizio","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","full_name":"Olmeda, Fabrizio","last_name":"Olmeda"},{"first_name":"Misha","last_name":"Gupta","full_name":"Gupta, Misha"},{"last_name":"Bektas","full_name":"Bektas, Onurcan","first_name":"Onurcan"},{"first_name":"Steffen","last_name":"Rulands","full_name":"Rulands, Steffen"}]},{"article_number":"017001","year":"2026","publisher":"American Physical Society","project":[{"grant_number":"101118866","name":"Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos","_id":"7bfe6a29-9f16-11ee-852c-c0da5e2045d9"}],"ddc":["570"],"article_processing_charge":"Yes","date_published":"2026-01-23T00:00:00Z","volume":4,"intvolume":"         4","author":[{"first_name":"David","orcid":"0000-0001-7205-2975","last_name":"Brückner","id":"e1e86031-6537-11eb-953a-f7ab92be508d","full_name":"Brückner, David"},{"last_name":"Tkačik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","full_name":"Tkačik, Gašper","first_name":"Gašper","orcid":"0000-0002-6699-1455"}],"_id":"21282","external_id":{"arxiv":["2510.24536"]},"acknowledgement":"We thank Edouard Hannezo, Anna Kicheva, Fridtjof Brauns, and all members of the Brückner and Tkačik groups for feedback and inspiring discussions. This work was supported in part by European Research Council ERC-2023-SyG “Dynatrans” Grant No. 101118866 (G.T.). This work was conducted while visiting the Okinawa Institute of Science and Technology (OIST) through the Theoretical Sciences Visiting Program (TSVP); at the Kavli Institute for Theoretical Physics (KITP) Santa Barbara, supported by NSF Grant No. PHY-1748958 and the Gordon and Betty Moore Foundation Grant No. 2919.02; and at Lucullus, Vienna.","status":"public","file":[{"content_type":"application/pdf","relation":"main_file","checksum":"99ef02dd741c4536eeefd12d409d5269","success":1,"access_level":"open_access","date_updated":"2026-02-24T06:57:44Z","file_size":1147994,"creator":"dernst","date_created":"2026-02-24T06:57:44Z","file_id":"21352","file_name":"2026_PRXLife_Brueckner.pdf"}],"citation":{"ista":"Brückner D, Tkačik G. 2026. Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. PRX Life. 4, 017001.","short":"D. Brückner, G. Tkačik, PRX Life 4 (2026).","mla":"Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic Development: Information, Dynamical Systems, Gene Networks.” <i>PRX Life</i>, vol. 4, 017001, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/fdcf-dkws\">10.1103/fdcf-dkws</a>.","chicago":"Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic Development: Information, Dynamical Systems, Gene Networks.” <i>PRX Life</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/fdcf-dkws\">https://doi.org/10.1103/fdcf-dkws</a>.","ama":"Brückner D, Tkačik G. Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. <i>PRX Life</i>. 2026;4. doi:<a href=\"https://doi.org/10.1103/fdcf-dkws\">10.1103/fdcf-dkws</a>","apa":"Brückner, D., &#38; Tkačik, G. (2026). Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. <i>PRX Life</i>. American Physical Society. <a href=\"https://doi.org/10.1103/fdcf-dkws\">https://doi.org/10.1103/fdcf-dkws</a>","ieee":"D. Brückner and G. Tkačik, “Marr’s three levels for embryonic development: Information, dynamical systems, gene networks,” <i>PRX Life</i>, vol. 4. American Physical Society, 2026."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"arxiv":1,"quality_controlled":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","corr_author":"1","month":"01","day":"23","doi":"10.1103/fdcf-dkws","publication_status":"published","department":[{"_id":"GaTk"}],"PlanS_conform":"1","file_date_updated":"2026-02-24T06:57:44Z","date_updated":"2026-02-24T07:00:16Z","DOAJ_listed":"1","type":"journal_article","abstract":[{"lang":"eng","text":"Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge autonomously through cellular interactions. We propose that both extremes—as well as the continuum of intermediate cases—can be conceptualized as information-processing systems, whose operation can be described using “Marr's three levels of analysis”: the computational problem being solved, the algorithms employed, and their molecular implementation. At the first level, we argue that normative theories, such as information-theoretic optimization principles, provide a formalization of the computational problem. At the second level, we show how simplified information-processing architectures provide a framework for developmental algorithms, which are formalized mathematically using dynamical systems theory. At the third level, the implementation of developmental algorithms is described by mechanistic biophysical and gene regulatory network models."}],"publication_identifier":{"eissn":["2835-8279"]},"date_created":"2026-02-17T08:29:10Z","publication":"PRX Life","oa":1,"has_accepted_license":"1","OA_place":"publisher","article_type":"original","OA_type":"gold","title":"Marr's three levels for embryonic development: Information, dynamical systems, gene networks","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"_id":"21284","author":[{"orcid":"0000-0002-6401-5151","first_name":"Lea Marie","full_name":"Becker, Lea Marie","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","last_name":"Becker"},{"last_name":"Schanda","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","full_name":"Schanda, Paul","first_name":"Paul","orcid":"0000-0002-9350-7606"}],"publisher":"Institute of Science and Technology Austria","ddc":["541"],"year":"2026","date_published":"2026-02-18T00:00:00Z","article_processing_charge":"No","abstract":[{"text":"The advantageous characteristics attributed to the 19F nucleus have made it a popular target for NMR once again in recent years. Aside from solution NMR, an increasing number of studies have been conducted applying solid-state magic-angle-spinning NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and strong dipolar couplings can be utilized to get structural insights into proteins and measure long distances. Despite increasing popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and 13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially reduces measurement times of 19F MAS NMR experiments without compromising resolution. Additionally, we report the chemical-shift assignments of all four fluorotryptophan signals in the 12 × 39 kDa large protein using a mutagenesis approach.","lang":"eng"}],"date_created":"2026-02-17T10:17:14Z","file_date_updated":"2026-02-17T10:11:14Z","type":"research_data","date_updated":"2026-06-10T09:28:41Z","OA_place":"repository","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","title":"Research data for \"Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants\"","OA_type":"free access","oa":1,"has_accepted_license":"1","status":"public","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)"},"file":[{"creator":"lbecker","file_size":36996027,"date_updated":"2026-02-17T10:11:14Z","file_name":"Research_data.zip","date_created":"2026-02-17T10:11:14Z","file_id":"21285","checksum":"2d3105f26be578073b88ee1f2ea0bdb1","relation":"main_file","content_type":"application/zip","access_level":"open_access","success":1},{"checksum":"e24aebcdb8856cb181cbaa02de020ddb","relation":"table_of_contents","content_type":"text/plain","access_level":"open_access","creator":"lbecker","file_size":1993,"date_updated":"2026-02-17T10:11:14Z","file_name":"README.txt","date_created":"2026-02-17T10:11:14Z","file_id":"21286"}],"citation":{"mla":"Becker, Lea Marie, and Paul Schanda. <i>Research Data for “Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>.","chicago":"Becker, Lea Marie, and Paul Schanda. “Research Data for ‘Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">https://doi.org/10.15479/AT-ISTA-21284</a>.","short":"L.M. Becker, P. Schanda, (2026).","ista":"Becker LM, Schanda P. 2026. Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>.","ieee":"L. M. Becker and P. Schanda, “Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.’” Institute of Science and Technology Austria, 2026.","apa":"Becker, L. M., &#38; Schanda, P. (2026). Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">https://doi.org/10.15479/AT-ISTA-21284</a>","ama":"Becker LM, Schanda P. Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>"},"acknowledgement":"We thank Ben P. Tatman for insightful discussions. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support Facility.","month":"2","corr_author":"1","department":[{"_id":"GradSch"},{"_id":"PaSc"}],"doi":"10.15479/AT-ISTA-21284","day":"18","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"contributor":[{"first_name":"Giorgia","last_name":"Toscano","contributor_type":"researcher","id":"334a5e40-8747-11f0-b671-ba1f5154b4b4"},{"first_name":"Anna","last_name":"Kapitonova","contributor_type":"researcher","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471"},{"id":"a3089acd-6806-11ee-bacc-f0c7d500ad20","contributor_type":"researcher","last_name":"Singh","first_name":"Rajkumar"},{"id":"bb74f472-ae54-11eb-9835-bc9c22fb1183","contributor_type":"researcher","last_name":"Guillerm","first_name":"Undina"},{"first_name":"Roman","last_name":"Lichtenecker","contributor_type":"researcher"}],"oa_version":"Published Version"},{"oa":1,"author":[{"first_name":"Feyza","last_name":"Polat Haas","full_name":"Polat Haas, Feyza"},{"orcid":"0000-0002-5615-5277","first_name":"Ana","full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","last_name":"Villalba Requena"},{"first_name":"Polina","full_name":"Rusina, Polina","last_name":"Rusina"},{"full_name":"Gopalan, Anusha","last_name":"Gopalan","first_name":"Anusha"},{"full_name":"Fritz, Hector","last_name":"Fritz","first_name":"Hector"},{"first_name":"Azamat","last_name":"Akhmetkaliyev","full_name":"Akhmetkaliyev, Azamat"},{"first_name":"Frank","full_name":"Ruehle, Frank","last_name":"Ruehle"},{"first_name":"Anna","full_name":"Einsiedel, Anna","last_name":"Einsiedel"},{"full_name":"Szczepinska, Anna","last_name":"Szczepinska","first_name":"Anna"},{"first_name":"Fridolin","last_name":"Kielisch","full_name":"Kielisch, Fridolin"},{"first_name":"Jia-Xuan","full_name":"Chen, Jia-Xuan","last_name":"Chen"},{"last_name":"Nguyen","full_name":"Nguyen, Susanne","first_name":"Susanne"},{"first_name":"Thierry","full_name":"Schmidlin, Thierry","last_name":"Schmidlin"},{"first_name":"Simon","orcid":"0000-0003-2279-1061","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"},{"last_name":"Bailicata","full_name":"Bailicata, M. Felicia","first_name":"M. Felicia"},{"full_name":"Keller Valsecchi, Claudia Isabelle","last_name":"Keller Valsecchi","first_name":"Claudia Isabelle"}],"OA_type":"green","_id":"21290","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"The splicing paralogues SNRPB and SNRPN control differential metabolic states.","OA_place":"repository","date_updated":"2026-02-23T11:03:33Z","type":"preprint","publication":"bioRxiv","date_created":"2026-02-17T11:35:59Z","abstract":[{"text":"Gene duplication underlies evolutionary innovation, yet many paralogues remain highly similar, raising questions about their functional divergence and physiological relevance. The spliceosomal Sm core protein SNRPB and its mammalian-specific paralogue SNRPN share over 90% sequence identity, but their distinct expression patterns - SNRPB being ubiquitous and SNRPN confined to the brain - suggest specialized functions. Why mammals have two different spliceosomes has remained obscure. Here, we generated isogenic human cell lines expressing ectopically either SNRPB or SNRPN exclusively and found that SNRPN stabilizes transcripts involved in energy metabolism and mitochondrial function, leading to increased mitochondrial abundance and oxygen consumption. Despite similar spliceosomal interactomes, SNRPN more strongly associates with the PRMT5 methylosome complex and exhibits dynamic arginine methylation in its C-terminal region that is sensitive to translation inhibition and amino acid availability. The SNRPN-dependent transcriptome responds to translation inhibition by stabilizing long, intron-rich genes involved in amino acid and energy metabolism. Our findings reveal a nutrient-sensitive, methylation-dependent mechanism that differentiates the two paralogues. This suggests that SNRPN functions as a metabolic-specialized spliceosomal subunit thereby providing tissue-specific adaptation of RNA processing in mammals.","lang":"eng"}],"oa_version":"Preprint","language":[{"iso":"eng"}],"article_processing_charge":"No","day":"11","doi":"10.64898/2026.02.11.705284","publication_status":"submitted","department":[{"_id":"SiHi"}],"month":"02","date_published":"2026-02-11T00:00:00Z","acknowledgement":"We thank Oliver Mühlemann and Alex Hofer (University of Bern) for sharing SMG inhibitors\r\nand for their expertise in nonsense-mediated mRNA decay and Maria Hondele for critical\r\nreading of the manuscript draft. We also thank the IMB Genomics Core Facility for assistance\r\nwith library preparation and sequencing, Martin Möckel and the IMB Protein Production Core\r\nFacility for providing enzymes used in this work, Marton Gelleri together with the IMB\r\nMicroscopy Core Facility for support with microscopy and FRAP experiments, Jasmin Cartano\r\nfor proteomics sample processing and the IMB Flow Cytometry Core Facility for support. In\r\naddition, we thank the Imaging Core Facility (IMCF) and the FACS Core Facility at the\r\nBiozentrum, University of Basel, for technical assistance. CIKV acknowledges funding by the\r\nDeutsche Forschungsgemeinschaft (DFG, German Research Foundation) - Individual Grant\r\nProject no. 513744403, Scientific Network Grant Project no. 531902894, GRK2526 “Genevo”\r\n- Project no. 407023052”, GRK2859 (“4R”) - Project no. 491145305, Forschungsinitiative\r\nRheinland-Pfalz (ReALity), the EMBO Young Investigator Program (5795), institutional\r\nfunding from the Institute of Molecular Biology and funds from the Kanton Basel-Stadt and\r\nBasel-Land provided to the Biozentrum of the University Basel. J.H.G.F.G. was part of the\r\n‘Science of Healthy Ageing Research Programme’ (SHARP) initiative funded by RhinelandPalatinate’s Ministry of Science, Education and Culture. PR is funded by the Biozentrum PhD\r\nFellowships Program. MFB received financial support from the intramural High Potentials\r\nGrant program of the University Medical Center Mainz, Forschungsinitiative Rheinland-Pfalz\r\n(ReALity) and Stiftungen zugunsten der Medizinischen Fakultät der LMU Klinikum (26069).\r\nInstruments in the IMB core facilities were supported by funds from the DFG: Laser Scanning\r\nConfocal (Leica Stellaris 8 Falcon, funded by the DFG - Project #497669232), Orbitrap Astral system (funded by the DFG - Project #524805621) and BD LSRFortessa SOPR is funded by\r\nthe DFG - Project #210253511.\r\n","year":"2026","citation":{"apa":"Polat Haas, F., Villalba Requena, A., Rusina, P., Gopalan, A., Fritz, H., Akhmetkaliyev, A., … Keller Valsecchi, C. I. (n.d.). The splicing paralogues SNRPB and SNRPN control differential metabolic states. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.02.11.705284\">https://doi.org/10.64898/2026.02.11.705284</a>","ama":"Polat Haas F, Villalba Requena A, Rusina P, et al. The splicing paralogues SNRPB and SNRPN control differential metabolic states. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.02.11.705284\">10.64898/2026.02.11.705284</a>","ieee":"F. Polat Haas <i>et al.</i>, “The splicing paralogues SNRPB and SNRPN control differential metabolic states.,” <i>bioRxiv</i>. .","ista":"Polat Haas F, Villalba Requena A, Rusina P, Gopalan A, Fritz H, Akhmetkaliyev A, Ruehle F, Einsiedel A, Szczepinska A, Kielisch F, Chen J-X, Nguyen S, Schmidlin T, Hippenmeyer S, Bailicata MF, Keller Valsecchi CI. The splicing paralogues SNRPB and SNRPN control differential metabolic states. bioRxiv, <a href=\"https://doi.org/10.64898/2026.02.11.705284\">10.64898/2026.02.11.705284</a>.","short":"F. Polat Haas, A. Villalba Requena, P. Rusina, A. Gopalan, H. Fritz, A. Akhmetkaliyev, F. Ruehle, A. Einsiedel, A. Szczepinska, F. Kielisch, J.-X. Chen, S. Nguyen, T. Schmidlin, S. Hippenmeyer, M.F. Bailicata, C.I. Keller Valsecchi, BioRxiv (n.d.).","mla":"Polat Haas, Feyza, et al. “The Splicing Paralogues SNRPB and SNRPN Control Differential Metabolic States.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.02.11.705284\">10.64898/2026.02.11.705284</a>.","chicago":"Polat Haas, Feyza, Ana Villalba Requena, Polina Rusina, Anusha Gopalan, Hector Fritz, Azamat Akhmetkaliyev, Frank Ruehle, et al. “The Splicing Paralogues SNRPB and SNRPN Control Differential Metabolic States.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.02.11.705284\">https://doi.org/10.64898/2026.02.11.705284</a>."},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.02.11.705284"}],"status":"public"},{"has_accepted_license":"1","oa":1,"OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Lineage origin of spinal cord cell type diversity","OA_type":"green","type":"preprint","date_updated":"2026-04-14T08:16:55Z","abstract":[{"text":"The complexity and specificity of movement in vertebrates is driven by a rich diversity of spinal motor and interneuron cell types. During development, eleven spinal cord progenitor domains generate an equivalent number of cardinal neuron types. How progenitor domains, individual progenitors, and post-mitotic diversity relate is still unknown. We performed high-resolution, single-progenitor cell lineage tracing in the embryonic mouse spinal cord using mosaic analysis with double markers (MADM). Our quantitative study of lineage progression revealed that spinal cord progenitors undergo highly variable numbers of proliferative, neurogenic, and gliogenic cell divisions. The nascent clonally-related neurons migrate radially over large distances, span the dorsoventral axis, and even cross the midline, demonstrating striking bilaterality. Molecular and morphometric analysis indicate high levels of progenitor multipotency, with an individual progenitor capable of producing several molecularly and morphologically distinct neuron types, as well as astrocytes. These findings redefine spinal cord development as a process in which lineage variability — rather than rigid progenitor identity — drives the generation of cellular diversity.","lang":"eng"}],"publication":"bioRxiv","date_created":"2026-02-17T11:36:20Z","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"}],"oa_version":"Preprint","language":[{"iso":"eng"}],"month":"02","corr_author":"1","department":[{"_id":"SiHi"},{"_id":"LoSw"}],"publication_status":"submitted","doi":"10.64898/2026.02.12.705305","day":"16","acknowledgement":"We would like to thank Elizabeth Marin, Anna Kicheva, Igor Adameyko, and James Briscoe as\r\nwell as members of the Sweeney and Hippemeyer labs and SFB consortium for comments on\r\nthe manuscript. We are also grateful for the technical support of the Preclinical and Imaging and\r\nOptics Facilities support teams (ISTA). In addition, we thank our funding sources for providing\r\nthe resources to do these experiments: Horizon Europe ERC Starting Grant Number 101041551\r\n(M.S.; L.B.S.); Special Research Program (SFB) of the Austrian Science Fund (FWF)\r\nNeuroStem Modulation Project numbers F7814-B (S.A.G.; M.S.; G.S.; and L.B.S.) and F7805\r\n(G.C. and S.H.). S.A.G is supported by a Boehringer Ingelheim Fonds PhD Fellowship, F.D.S.N.\r\nby an Institute of Science and Technology Austria (ISTA) GROW fellowship, and G.C. by an\r\nISTA Plus postdoctoral fellowship from the European Commission. S.H./L.B.S. and G.C. were\r\nadditionally supported by institutional funds from the ISTA and the University of Exeter,\r\nrespectively. ","main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.02.12.705305"}],"status":"public","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"citation":{"mla":"Gobeil, Sophie A., et al. “Lineage Origin of Spinal Cord Cell Type Diversity.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.02.12.705305\">10.64898/2026.02.12.705305</a>.","short":"S.A. Gobeil, F. Da Silveira Neto, G. Silvestrelli, M.G. Smits, C. Streicher, G.T. Cheung, S. Hippenmeyer, L.B. Sweeney, BioRxiv (n.d.).","chicago":"Gobeil, Sophie A, Francisco Da Silveira Neto, Giulia Silvestrelli, Matthijs Geert Smits, Carmen Streicher, Giselle T Cheung, Simon Hippenmeyer, and Lora B. Sweeney. “Lineage Origin of Spinal Cord Cell Type Diversity.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.02.12.705305\">https://doi.org/10.64898/2026.02.12.705305</a>.","ista":"Gobeil SA, Da Silveira Neto F, Silvestrelli G, Smits MG, Streicher C, Cheung GT, Hippenmeyer S, Sweeney LB. Lineage origin of spinal cord cell type diversity. bioRxiv, <a href=\"https://doi.org/10.64898/2026.02.12.705305\">10.64898/2026.02.12.705305</a>.","ieee":"S. A. Gobeil <i>et al.</i>, “Lineage origin of spinal cord cell type diversity,” <i>bioRxiv</i>. .","ama":"Gobeil SA, Da Silveira Neto F, Silvestrelli G, et al. Lineage origin of spinal cord cell type diversity. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.02.12.705305\">10.64898/2026.02.12.705305</a>","apa":"Gobeil, S. A., Da Silveira Neto, F., Silvestrelli, G., Smits, M. G., Streicher, C., Cheung, G. T., … Sweeney, L. B. (n.d.). Lineage origin of spinal cord cell type diversity. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.02.12.705305\">https://doi.org/10.64898/2026.02.12.705305</a>"},"author":[{"first_name":"Sophie A","full_name":"Gobeil, Sophie A","id":"2f3e9efb-eb24-11ec-86b2-88efb11d59fa","last_name":"Gobeil"},{"id":"8cfb7412-10a7-11f1-add1-82b44e6418f2","full_name":"Da Silveira Neto, Francisco","last_name":"Da Silveira Neto","first_name":"Francisco"},{"first_name":"Giulia","id":"12632ae8-799e-11ef-94a2-e5a3b5ef49e9","full_name":"Silvestrelli, Giulia","last_name":"Silvestrelli"},{"id":"7a231d52-e216-11ee-a0bb-8acd55f8f1f0","full_name":"Smits, Matthijs Geert","last_name":"Smits","first_name":"Matthijs Geert"},{"last_name":"Streicher","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","first_name":"Carmen"},{"first_name":"Giselle T","orcid":"0000-0001-8457-2572","id":"471195F6-F248-11E8-B48F-1D18A9856A87","full_name":"Cheung, Giselle T","last_name":"Cheung"},{"last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon","first_name":"Simon","orcid":"0000-0003-2279-1061"},{"orcid":"0000-0001-9242-5601","first_name":"Lora Beatrice Jaeger","full_name":"Sweeney, Lora Beatrice Jaeger","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","last_name":"Sweeney"}],"_id":"21291","article_processing_charge":"No","date_published":"2026-02-16T00:00:00Z","year":"2026","project":[{"grant_number":"101041551","name":"Development and Evolution of Tetrapod Motor Circuits","_id":"ebb66355-77a9-11ec-83b8-b8ac210a4dae"},{"grant_number":"F7814","name":"Stem Cell Modulation in Neural Development and Regeneration/ P14-Swim-to-limb transition: cell type to connection diversity","_id":"8da85f50-16d5-11f0-9cad-eab8b0ff6c9e"},{"name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F7805","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E"}],"ddc":["570"]},{"arxiv":1,"language":[{"iso":"eng"}],"oa_version":"Published Version","quality_controlled":"1","corr_author":"1","month":"02","doi":"10.1038/s41567-025-03166-3","day":"17","department":[{"_id":"GradSch"},{"_id":"BjHo"}],"publication_status":"epub_ahead","scopus_import":"1","acknowledgement":"The work was supported by the Simons Foundation (grant number 662960, to B.H.). Open access funding provided by Institute of Science and Technology (IST Austria).","status":"public","citation":{"ista":"Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. 2026. Discontinuous transition to shear flow turbulence. Nature Physics.","chicago":"Yang, Bowen, Yi Zhuang, Gökhan Yalniz, Mukund Vasudevan, Elena Marensi, and Björn Hof. “Discontinuous Transition to Shear Flow Turbulence.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03166-3\">https://doi.org/10.1038/s41567-025-03166-3</a>.","short":"B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, B. Hof, Nature Physics (2026).","mla":"Yang, Bowen, et al. “Discontinuous Transition to Shear Flow Turbulence.” <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41567-025-03166-3\">10.1038/s41567-025-03166-3</a>.","apa":"Yang, B., Zhuang, Y., Yalniz, G., Vasudevan, M., Marensi, E., &#38; Hof, B. (2026). Discontinuous transition to shear flow turbulence. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03166-3\">https://doi.org/10.1038/s41567-025-03166-3</a>","ama":"Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. Discontinuous transition to shear flow turbulence. <i>Nature Physics</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41567-025-03166-3\">10.1038/s41567-025-03166-3</a>","ieee":"B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, and B. Hof, “Discontinuous transition to shear flow turbulence,” <i>Nature Physics</i>. Springer Nature, 2026."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"has_accepted_license":"1","OA_place":"publisher","article_type":"original","OA_type":"hybrid","title":"Discontinuous transition to shear flow turbulence","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","PlanS_conform":"1","date_updated":"2026-02-23T11:36:46Z","type":"journal_article","abstract":[{"lang":"eng","text":"Depending on the type of flow, the transition to turbulence can take one of two forms: either turbulence arises from a sequence of instabilities or from the spatial proliferation of transiently chaotic domains, a process analogous to directed percolation. The former scenario is commonly referred to as a supercritical transition and frequently encountered in flows destabilized by body forces, whereas the latter subcritical transition is common in shear flows. Both cases are inherently continuous in a sense that the transformation from ordered laminar to fully turbulent fluid motion is only accomplished gradually with flow speed. Here we show that these established transition types do not account for the more general setting of shear flows subject to body forces. The combination of the two continuous scenarios leads to the attenuation of spatial coupling; with increasing forcing amplitude, the transition becomes increasingly sharp and eventually discontinuous. We argue that the suppression of laminar–turbulent coexistence and the approach towards a discontinuous phase transition potentially apply to a broad range of situations including flows subject to, for example, buoyancy, centrifugal or electromagnetic forces."}],"publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"date_created":"2026-02-17T11:38:41Z","publication":"Nature Physics","article_processing_charge":"Yes (via OA deal)","date_published":"2026-02-17T00:00:00Z","year":"2026","publisher":"Springer Nature","project":[{"_id":"238598C6-32DE-11EA-91FC-C7463DDC885E","grant_number":"662960","name":"Revisiting the Turbulence Problem Using Statistical Mechanics"}],"ddc":["532"],"author":[{"first_name":"Bowen","orcid":"0000-0002-4843-6853","last_name":"Yang","id":"71b6ff4b-15b2-11ec-abd3-aef6b028cf7e","full_name":"Yang, Bowen"},{"last_name":"Zhuang","full_name":"Zhuang, Yi","id":"3677B57C-F248-11E8-B48F-1D18A9856A87","first_name":"Yi"},{"last_name":"Yalniz","id":"66E74FA2-D8BF-11E9-8249-8DE2E5697425","full_name":"Yalniz, Gökhan","first_name":"Gökhan","orcid":"0000-0002-8490-9312"},{"full_name":"Vasudevan, Mukund","id":"3C5A959A-F248-11E8-B48F-1D18A9856A87","last_name":"Vasudevan","first_name":"Mukund"},{"first_name":"Elena","orcid":"0000-0001-7173-4923","last_name":"Marensi","id":"0BE7553A-1004-11EA-B805-18983DDC885E","full_name":"Marensi, Elena"},{"last_name":"Hof","id":"3A374330-F248-11E8-B48F-1D18A9856A87","full_name":"Hof, Björn","first_name":"Björn","orcid":"0000-0003-2057-2754"}],"external_id":{"arxiv":["2311.11474"]},"_id":"21295"},{"publication_identifier":{"eissn":["2509-9434"],"issn":["2509-9426"]},"publication":"Earth Systems and Environment","date_created":"2026-02-18T07:11:14Z","abstract":[{"lang":"eng","text":"Air pollution is a critical public health issue worldwide, South America faces unique challenges due to rapid urban growth, industrial expansion, and recurrent biomass burning. Existing studies have largely focused on regional or national scales, overlooking detailed spatio-temporal dynamics in cities. This study provides a comprehensive assessment of air pollution spatio-temporal trends from 2013 to 2023 in six major South American cities: Bogotá, Buenos Aires, Montevideo, Quito, Santiago de Chile, and São Paulo. We evaluated four key pollutants, NO2, O3, PM10, and PM2.5, using in situ monitoring networks complemented with reanalysis (boundary layer and pollution dynamics), and fire detections datasets (biomass burning). A key innovation is the use of a Lagrangian Tracker, which identifies persistent hotspots and transport pathways of pollutants, offering new insights into transboundary pollution. Results show that nearly all cities experienced reductions in particulate matter concentrations, while three of the six cities exhibited rising O3 levels, reflecting complex interactions between emissions, meteorology, and atmospheric chemistry. Santiago de Chile recorded the highest levels of NO2 and PM, strongly influenced by topography and biomass burning in JJA. Bogotá and Quito were notably impacted by regional fire emissions, whereas coastal cities such as Buenos Aires and Montevideo benefited from greater pollutant dispersion but still exceeded the World Health Organization guidelines. By integrating ground-based, satellite, and reanalysis data with advanced trajectory modeling, this research provides detailed spatio-temporal evaluations of air pollution in South America and highlights the urgent need for coordinated regional strategies to reduce health and economic burdens."}],"date_updated":"2026-02-23T11:57:21Z","type":"journal_article","PlanS_conform":"1","OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Spatio-temporal trends of air pollution in six South American cities","OA_place":"publisher","article_type":"original","has_accepted_license":"1","oa":1,"citation":{"chicago":"González, Yuri, Nicolás Malagón, Kevin Benavides, Luis Carlos Belalcázar, Ellie Anne Lopez-Barrera, and Alejandro Casallas Garcia. “Spatio-Temporal Trends of Air Pollution in Six South American Cities.” <i>Earth Systems and Environment</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s41748-026-01068-9\">https://doi.org/10.1007/s41748-026-01068-9</a>.","short":"Y. González, N. Malagón, K. Benavides, L.C. Belalcázar, E.A. Lopez-Barrera, A. Casallas Garcia, Earth Systems and Environment (2026).","mla":"González, Yuri, et al. “Spatio-Temporal Trends of Air Pollution in Six South American Cities.” <i>Earth Systems and Environment</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s41748-026-01068-9\">10.1007/s41748-026-01068-9</a>.","ista":"González Y, Malagón N, Benavides K, Belalcázar LC, Lopez-Barrera EA, Casallas Garcia A. 2026. Spatio-temporal trends of air pollution in six South American cities. Earth Systems and Environment.","ieee":"Y. González, N. Malagón, K. Benavides, L. C. Belalcázar, E. A. Lopez-Barrera, and A. Casallas Garcia, “Spatio-temporal trends of air pollution in six South American cities,” <i>Earth Systems and Environment</i>. Springer Nature, 2026.","ama":"González Y, Malagón N, Benavides K, Belalcázar LC, Lopez-Barrera EA, Casallas Garcia A. Spatio-temporal trends of air pollution in six South American cities. <i>Earth Systems and Environment</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s41748-026-01068-9\">10.1007/s41748-026-01068-9</a>","apa":"González, Y., Malagón, N., Benavides, K., Belalcázar, L. C., Lopez-Barrera, E. A., &#38; Casallas Garcia, A. (2026). Spatio-temporal trends of air pollution in six South American cities. <i>Earth Systems and Environment</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s41748-026-01068-9\">https://doi.org/10.1007/s41748-026-01068-9</a>"},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"main_file_link":[{"url":"https://doi.org/10.1007/s41748-026-01068-9","open_access":"1"}],"status":"public","scopus_import":"1","acknowledgement":"The author would like to thank Fundación Universitaria Los Libertadores (Project ID: ING-40-25) for supporting her in this work. And EALB, would like to thank Universidad Sergio Arboleda (Project ID: IN.BG.086.24.015) for supporting her in this work. Open access funding provided by Institute of Science and Technology (IST Austria). The first author was funded by the Fundacion Universitaria Los Libertadores (Project ID: ING-40-25). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 101034413289 awarded to AC. EALB was supported by Universidad Sergio Arboleda (Project ID: IN.BG.086.24.015).","day":"17","doi":"10.1007/s41748-026-01068-9","publication_status":"epub_ahead","department":[{"_id":"CaMu"}],"corr_author":"1","month":"02","oa_version":"Published Version","language":[{"iso":"eng"}],"quality_controlled":"1","_id":"21311","author":[{"first_name":"Yuri","last_name":"González","full_name":"González, Yuri"},{"first_name":"Nicolás","full_name":"Malagón, Nicolás","last_name":"Malagón"},{"first_name":"Kevin","full_name":"Benavides, Kevin","last_name":"Benavides"},{"full_name":"Belalcázar, Luis Carlos","last_name":"Belalcázar","first_name":"Luis Carlos"},{"first_name":"Ellie Anne","last_name":"Lopez-Barrera","full_name":"Lopez-Barrera, Ellie Anne"},{"id":"92081129-2d75-11ef-a48d-b04dd7a2385a","full_name":"Casallas Garcia, Alejandro","last_name":"Casallas Garcia","first_name":"Alejandro","orcid":"0000-0002-1988-5035"}],"ddc":["550"],"publisher":"Springer Nature","year":"2026","date_published":"2026-02-17T00:00:00Z","article_processing_charge":"Yes (via OA deal)"},{"publisher":"American Association for the Advancement of Science","ddc":["530"],"article_number":"eady7222","year":"2026","date_published":"2026-02-13T00:00:00Z","article_processing_charge":"Yes","intvolume":"        12","volume":12,"_id":"21340","issue":"7","external_id":{"arxiv":["2504.09721"]},"author":[{"id":"1f6212b5-f795-11ec-9c0c-de4780302890","full_name":"Bubis, Anton","last_name":"Bubis","first_name":"Anton"},{"first_name":"Lucia","last_name":"Vigliotti","full_name":"Vigliotti, Lucia","id":"539e1e1a-e604-11ee-a1df-f02b018e5c8c"},{"last_name":"Serbyn","full_name":"Serbyn, Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2399-5827","first_name":"Maksym"},{"last_name":"Higginbotham","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","full_name":"Higginbotham, Andrew P","first_name":"Andrew P","orcid":"0000-0003-2607-2363"}],"status":"public","file":[{"checksum":"8402f322f8f0e858b1d9aac57e306e31","relation":"main_file","content_type":"application/pdf","access_level":"open_access","success":1,"creator":"dernst","file_size":2775975,"date_updated":"2026-02-24T07:23:32Z","file_name":"2026_ScienceAdv_Bubis.pdf","date_created":"2026-02-24T07:23:32Z","file_id":"21353"}],"citation":{"ieee":"A. Bubis, L. Vigliotti, M. Serbyn, and A. P. Higginbotham, “Non-equilibrium plasmon liquid in a Josephson junction chain,” <i>Science Advances</i>, vol. 12, no. 7. American Association for the Advancement of Science, 2026.","ama":"Bubis A, Vigliotti L, Serbyn M, Higginbotham AP. Non-equilibrium plasmon liquid in a Josephson junction chain. <i>Science Advances</i>. 2026;12(7). doi:<a href=\"https://doi.org/10.1126/sciadv.ady7222\">10.1126/sciadv.ady7222</a>","apa":"Bubis, A., Vigliotti, L., Serbyn, M., &#38; Higginbotham, A. P. (2026). Non-equilibrium plasmon liquid in a Josephson junction chain. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.ady7222\">https://doi.org/10.1126/sciadv.ady7222</a>","chicago":"Bubis, Anton, Lucia Vigliotti, Maksym Serbyn, and Andrew P Higginbotham. “Non-Equilibrium Plasmon Liquid in a Josephson Junction Chain.” <i>Science Advances</i>. American Association for the Advancement of Science, 2026. <a href=\"https://doi.org/10.1126/sciadv.ady7222\">https://doi.org/10.1126/sciadv.ady7222</a>.","mla":"Bubis, Anton, et al. “Non-Equilibrium Plasmon Liquid in a Josephson Junction Chain.” <i>Science Advances</i>, vol. 12, no. 7, eady7222, American Association for the Advancement of Science, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.ady7222\">10.1126/sciadv.ady7222</a>.","short":"A. Bubis, L. Vigliotti, M. Serbyn, A.P. Higginbotham, Science Advances 12 (2026).","ista":"Bubis A, Vigliotti L, Serbyn M, Higginbotham AP. 2026. Non-equilibrium plasmon liquid in a Josephson junction chain. Science Advances. 12(7), eady7222."},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"acknowledgement":"We thank V. Vitelli, M. Fruchart, and A. Burshstein for helpful input. We acknowledge technical support from the Nanofabrication Facility and the MIBA machine shop at IST Austria. This research was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP), by the Austrian Science Fund (FWF) SFB F86, and by the NOMIS foundation.","corr_author":"1","month":"02","day":"13","doi":"10.1126/sciadv.ady7222","publication_status":"published","department":[{"_id":"MaSe"},{"_id":"AnHi"},{"_id":"GeKa"}],"acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"arxiv":1,"oa_version":"Published Version","quality_controlled":"1","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Equilibrium quantum systems are often described by a gas of weakly interacting normal modes. Bringing such systems far from equilibrium, however, can drastically enhance mode-to-mode interactions. Understanding the resulting liquid is a fundamental question for quantum statistical mechanics and a practical question for engineering driven quantum devices. To tackle this question, we probe the non-equilibrium kinetics of one-dimensional plasmons in a long chain of Josephson junctions. We introduce multimode spectroscopy to controllably study the departure from equilibrium, witnessing the evolution from pairwise coupling between plasma modes at weak driving to dramatic, high-order, cascaded couplings at strong driving. Scaling to many-mode drives, we stimulate interactions between hundreds of modes, resulting in near-continuum internal dynamics. Imaging the resulting non-equilibrium plasmon populations, we then resolve the nonlocal redistribution of energy in the response to a weak perturbation—an explicit verification of the emergence of a strongly interacting, non-equilibrium liquid of plasmons."}],"publication_identifier":{"eissn":["2375-2548"]},"publication":"Science Advances","date_created":"2026-02-22T20:47:38Z","file_date_updated":"2026-02-24T07:23:32Z","PlanS_conform":"1","date_updated":"2026-02-24T07:25:34Z","DOAJ_listed":"1","type":"journal_article","OA_place":"publisher","article_type":"original","OA_type":"gold","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Non-equilibrium plasmon liquid in a Josephson junction chain","oa":1,"has_accepted_license":"1"},{"article_processing_charge":"No","date_published":"2026-02-01T00:00:00Z","article_number":"A165","year":"2026","ddc":["520"],"publisher":"EDP Sciences","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization"}],"author":[{"last_name":"Kotiwale","full_name":"Kotiwale, Gauri","id":"1438afc8-1ff6-11ee-9fa6-cd4a75d66875","first_name":"Gauri"},{"first_name":"Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J"},{"first_name":"Daichi","full_name":"Kashino, Daichi","last_name":"Kashino"},{"first_name":"Aswin P.","last_name":"Vijayan","full_name":"Vijayan, Aswin P."},{"first_name":"Alberto","orcid":"0000-0001-5586-6950","id":"018f0249-0e87-11f0-b167-cbce08fbd541","full_name":"Torralba Torregrosa, Alberto","last_name":"Torralba Torregrosa"},{"full_name":"Di Cesare, Claudia","id":"2d002343-372f-11ef-98ec-a164d20427cb","last_name":"Di Cesare","first_name":"Claudia"},{"last_name":"Iani","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a","full_name":"Iani, Edoardo","first_name":"Edoardo","orcid":"0000-0001-8386-3546"},{"first_name":"Rongmon","last_name":"Bordoloi","full_name":"Bordoloi, Rongmon"},{"last_name":"Leja","full_name":"Leja, Joel","first_name":"Joel"},{"last_name":"Maseda","full_name":"Maseda, Michael V.","first_name":"Michael V."},{"first_name":"Sandro","full_name":"Tacchella, Sandro","last_name":"Tacchella"},{"full_name":"Shivaei, Irene","last_name":"Shivaei","first_name":"Irene"},{"last_name":"Heintz","full_name":"Heintz, Kasper E.","first_name":"Kasper E."},{"last_name":"Danhaive","full_name":"Danhaive, A. Lola","first_name":"A. Lola"},{"full_name":"Mascia, Sara","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","last_name":"Mascia","first_name":"Sara"},{"first_name":"Ivan","orcid":"0000-0001-5346-6048","last_name":"Kramarenko","id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4","full_name":"Kramarenko, Ivan"},{"first_name":"Benjamín","full_name":"Navarrete, Benjamín","id":"aa14a535-50c9-11ef-b52e-e0c373d10148","last_name":"Navarrete"},{"last_name":"Mackenzie","full_name":"Mackenzie, Ruari","first_name":"Ruari"},{"first_name":"Rohan P.","full_name":"Naidu, Rohan P.","last_name":"Naidu"},{"full_name":"Sobral, David","last_name":"Sobral","first_name":"David"}],"_id":"21341","external_id":{"arxiv":["2510.19959"]},"volume":706,"intvolume":"       706","oa_version":"Published Version","quality_controlled":"1","language":[{"iso":"eng"}],"arxiv":1,"doi":"10.1051/0004-6361/202556597","day":"01","publication_status":"published","department":[{"_id":"JoMa"},{"_id":"GradSch"}],"month":"02","corr_author":"1","acknowledgement":"We thank the anonymous referee for the insightful comments that helped improving this paper. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Associations of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations were taken under programmes # 1243, # 1933 and # 3516. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. GK acknowledges support from the Foundation MERAC. APV acknowledge support from the Sussex Astronomy Centre STFC Consolidated Grant (ST/X001040/1).","scopus_import":"1","citation":{"mla":"Kotiwale, Gauri, et al. “Rapid, out-of-Equilibrium Metal Enrichment Indicated by a Flat Mass-Metallicity Relation at z ∼ 6 from NIRCam Grism Spectroscopy.” <i>Astronomy &#38; Astrophysics</i>, vol. 706, A165, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556597\">10.1051/0004-6361/202556597</a>.","chicago":"Kotiwale, Gauri, Jorryt J Matthee, Daichi Kashino, Aswin P. Vijayan, Alberto Torralba Torregrosa, Claudia Di Cesare, Edoardo Iani, et al. “Rapid, out-of-Equilibrium Metal Enrichment Indicated by a Flat Mass-Metallicity Relation at z ∼ 6 from NIRCam Grism Spectroscopy.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556597\">https://doi.org/10.1051/0004-6361/202556597</a>.","short":"G. Kotiwale, J.J. Matthee, D. Kashino, A.P. Vijayan, A. Torralba Torregrosa, C. Di Cesare, E. Iani, R. Bordoloi, J. Leja, M.V. Maseda, S. Tacchella, I. Shivaei, K.E. Heintz, A.L. Danhaive, S. Mascia, I. Kramarenko, B. Navarrete, R. Mackenzie, R.P. Naidu, D. Sobral, Astronomy &#38; Astrophysics 706 (2026).","ista":"Kotiwale G, Matthee JJ, Kashino D, Vijayan AP, Torralba Torregrosa A, Di Cesare C, Iani E, Bordoloi R, Leja J, Maseda MV, Tacchella S, Shivaei I, Heintz KE, Danhaive AL, Mascia S, Kramarenko I, Navarrete B, Mackenzie R, Naidu RP, Sobral D. 2026. Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. Astronomy &#38; Astrophysics. 706, A165.","ieee":"G. Kotiwale <i>et al.</i>, “Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy,” <i>Astronomy &#38; Astrophysics</i>, vol. 706. EDP Sciences, 2026.","apa":"Kotiwale, G., Matthee, J. J., Kashino, D., Vijayan, A. P., Torralba Torregrosa, A., Di Cesare, C., … Sobral, D. (2026). Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556597\">https://doi.org/10.1051/0004-6361/202556597</a>","ama":"Kotiwale G, Matthee JJ, Kashino D, et al. Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy. <i>Astronomy &#38; Astrophysics</i>. 2026;706. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556597\">10.1051/0004-6361/202556597</a>"},"file":[{"success":1,"access_level":"open_access","relation":"main_file","checksum":"6f5849d29ad43bee32f90152f6fc0294","content_type":"application/pdf","file_name":"2026_AstronomyAstrophysics_Kotiwale.pdf","date_created":"2026-02-24T07:46:47Z","file_id":"21355","file_size":6531719,"creator":"dernst","date_updated":"2026-02-24T07:46:47Z"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"status":"public","oa":1,"has_accepted_license":"1","OA_type":"diamond","title":"Rapid, out-of-equilibrium metal enrichment indicated by a flat mass-metallicity relation at z ∼ 6 from NIRCam grism spectroscopy","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","article_type":"original","date_updated":"2026-02-24T07:49:42Z","DOAJ_listed":"1","type":"journal_article","PlanS_conform":"1","file_date_updated":"2026-02-24T07:46:47Z","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"date_created":"2026-02-22T23:01:35Z","publication":"Astronomy & Astrophysics","abstract":[{"lang":"eng","text":"We aim to characterise the mass-metallicity relation (MZR) and the 3D correlation between the stellar mass, metallicity, and star formation rate (SFR) known as the fundamental metallicity relation (FMR) for galaxies at 5 < z < 7. Using ∼800 [O III] selected galaxies from deep NIRCam grism surveys, we present our stacked measurements of direct-Te metallicities, which we used to test recent strong-line metallicity calibrations. Our measured direct-Te metallicities (0.1–0.2 Z⊙ for M★ ≈ 5 × 107 − 9 M⊙, respectively) match recent JWST/NIRSpec-based results. However, there are significant inconsistencies between observations and hydrodynamical simulations. We observe a flatter MZR slope than the SPHINX20 and FLARES simulations, which cannot be attributed to selection effects. With simple models, we show that the effect of an [O III] flux-limited sample on the observed shape of the MZR is strongly dependent on the FMR. If the FMR is similar to the one in the local Universe, the intrinsic high-redshift MZR should be even flatter than is observed. In turn, a 3D relation where SFR correlates positively with metallicity at fixed mass would imply an intrinsically steeper MZR. Our measurements indicate that metallicity variations at fixed mass show little dependence on the SFR, suggesting a flat intrinsic MZR. This could indicate that the low-mass galaxies at these redshifts are out of equilibrium and that metal enrichment occurs rapidly in low-mass galaxies. However, being limited by our stacking analysis, we are yet to probe the scatter in the MZR and its dependence on SFR. Large carefully selected samples of galaxies with robust metallicity measurements can put tight constraints on the high-redshift FMR and help us to understand the interplay between gas flows, star formation, and feedback in early galaxies."}]}]