[{"month":"09","publication_status":"submitted","OA_type":"green","language":[{"iso":"eng"}],"_id":"21696","abstract":[{"lang":"eng","text":"We demonstrate an integrated photonic circuit based on feed forward photonic meshes that can be programmed and reconfigured to perform arbitrary spectral filter functions. We investigate a subset of the available filter functions, demonstrating that a N = 4 input triangular mesh with M = 3 layers may be operated via self-configuration algorithms to filter M arbitrary wavelengths from a given input spectrum. The tunable nature of the architecture enables preconfigured filter functions to be swept in the spectral domain continuously over the free spectral range of the device. This removes any strict requirements between the design parameters of the architecture and the center wavelength of a desired filter function. With this architecture, we experimentally demonstrate arbitrary wavelength rejection filters with contrasts as deep as 40 dB. Further, by intentionally selecting the center wavelengths of each filter function to lie along a wavelength grid we demonstrate deep wavelength division demultiplexing (DWDM) with inter-channel crosstalk between -25 dB and -40 dB. Unlike typical DWDM systems, in this architecture the center wavelength of each channel is not fixed at fabrication and instead may be swept or reordered arbitrarily. This device demonstrates advantages over typical methods for DWDM, Raman spectroscopy, and correlation spectroscopy as well as other applications."}],"author":[{"last_name":"Valdez","first_name":"Carson G.","full_name":"Valdez, Carson G."},{"last_name":"Kroo","first_name":"Anne R.","full_name":"Kroo, Anne R."},{"full_name":"Vlk, Marek","last_name":"Vlk","first_name":"Marek"},{"first_name":"Charles","last_name":"Roques-Carmes","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"last_name":"Fan","first_name":"Shanhui","full_name":"Fan, Shanhui"},{"last_name":"Miller","first_name":"David A. B.","full_name":"Miller, David A. B."},{"first_name":"Olav","last_name":"Solgaard","full_name":"Solgaard, Olav"}],"oa":1,"status":"public","article_processing_charge":"No","arxiv":1,"article_number":"2509.12059","fulldoi":"https://doi.org/10.48550/arXiv.2509.12059","doi":"10.48550/arXiv.2509.12059","date_published":"2025-09-15T00:00:00Z","extern":"1","oa_version":"Preprint","date_updated":"2026-04-13T11:01:05Z","OA_place":"repository","scopus_import":"1","day":"15","publication":"arXiv","title":"Programmable optical filters based on feed-forward photonic meshes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2025","type":"preprint","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2509.12059"}],"external_id":{"arxiv":["2509.12059"]},"citation":{"ista":"Valdez CG, Kroo AR, Vlk M, Roques-Carmes C, Fan S, Miller DAB, Solgaard O. Programmable optical filters based on feed-forward photonic meshes. arXiv, 2509.12059.","chicago":"Valdez, Carson G., Anne R. Kroo, Marek Vlk, Charles Roques-Carmes, Shanhui Fan, David A. B. Miller, and Olav Solgaard. “Programmable Optical Filters Based on Feed-Forward Photonic Meshes.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2509.12059\">https://doi.org/10.48550/arXiv.2509.12059</a>.","ama":"Valdez CG, Kroo AR, Vlk M, et al. Programmable optical filters based on feed-forward photonic meshes. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2509.12059\">10.48550/arXiv.2509.12059</a>","mla":"Valdez, Carson G., et al. “Programmable Optical Filters Based on Feed-Forward Photonic Meshes.” <i>ArXiv</i>, 2509.12059, doi:<a href=\"https://doi.org/10.48550/arXiv.2509.12059\">10.48550/arXiv.2509.12059</a>.","apa":"Valdez, C. G., Kroo, A. R., Vlk, M., Roques-Carmes, C., Fan, S., Miller, D. A. B., &#38; Solgaard, O. (n.d.). Programmable optical filters based on feed-forward photonic meshes. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2509.12059\">https://doi.org/10.48550/arXiv.2509.12059</a>","short":"C.G. Valdez, A.R. Kroo, M. Vlk, C. Roques-Carmes, S. Fan, D.A.B. Miller, O. Solgaard, ArXiv (n.d.).","ieee":"C. G. Valdez <i>et al.</i>, “Programmable optical filters based on feed-forward photonic meshes,” <i>arXiv</i>. ."},"date_created":"2026-04-09T09:10:41Z"},{"day":"20","publication":"arXiv","title":"Variational processing of multimode squeezed light","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","oa_version":"Preprint","date_updated":"2026-04-13T11:00:05Z","OA_place":"repository","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2509.16753"}],"external_id":{"arxiv":["2509.16753"]},"citation":{"mla":"Karnieli, Aviv, et al. “Variational Processing of Multimode Squeezed Light.” <i>ArXiv</i>, 2509.16753, doi:<a href=\"https://doi.org/10.48550/arXiv.2509.16753\">10.48550/arXiv.2509.16753</a>.","apa":"Karnieli, A., Mor, P.-A., Roques-Carmes, C., Lustig, E., Sloan, J., Vučković, J., … Fan, S. (n.d.). Variational processing of multimode squeezed light. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2509.16753\">https://doi.org/10.48550/arXiv.2509.16753</a>","short":"A. Karnieli, P.-A. Mor, C. Roques-Carmes, E. Lustig, J. Sloan, J. Vučković, D.A.B. Miller, S. Fan, ArXiv (n.d.).","ieee":"A. Karnieli <i>et al.</i>, “Variational processing of multimode squeezed light,” <i>arXiv</i>. .","ama":"Karnieli A, Mor P-A, Roques-Carmes C, et al. Variational processing of multimode squeezed light. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2509.16753\">10.48550/arXiv.2509.16753</a>","chicago":"Karnieli, Aviv, Paul-Alexis Mor, Charles Roques-Carmes, Eran Lustig, Jamison Sloan, Jelena Vučković, David A. B. Miller, and Shanhui Fan. “Variational Processing of Multimode Squeezed Light.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2509.16753\">https://doi.org/10.48550/arXiv.2509.16753</a>.","ista":"Karnieli A, Mor P-A, Roques-Carmes C, Lustig E, Sloan J, Vučković J, Miller DAB, Fan S. Variational processing of multimode squeezed light. arXiv, 2509.16753."},"date_created":"2026-04-09T09:10:41Z","year":"2025","type":"preprint","language":[{"iso":"eng"}],"abstract":[{"text":"Integrated multimode quantum optics is a promising platform for scalable continuous-variable quantum technologies leveraging multimode squeezing in both the spatial and spectral domains. However, on-chip measurement, routing and processing the relevant ``supermodes'' over which the squeezing resource is distributed still scales quadratically with the number of modes $N$, causing rapid increase in photonic circuit size and number of required measurements. Here, we introduce a variational scheme, relying on self-configuring photonic networks (SCN) that learns and extracts the most-squeezed supermodes sequentially, reducing both the circuit size and the experimental overhead. Using homodyne measurement as a cost function, a sparse SCN discovers the $l\\ll N$ most significant supermodes using $O(lN)$ physical elements and optimization steps. We analyze and numerically simulate these architectures for both real-space and frequency-domain implementations, showing a fidelity close to unity between the learned circuit and the supermode decomposition, even in the presence of optical losses and detection noise. In the frequency domain, we show that circuit size can be further reduced by using inverse-designed surrogate networks, which emulate the layers learned thus far. Using two different frequency encoding schemes -- uniformly- and non-uniformly-spaced frequency bins -- we reduce an entire network (learning all $N$ supermodes) to $O(N)$ and even $O(1)$ modulated cavities. Our results point toward chip-scale, resource-efficient quantum processing units and demultiplexers for continuous variable processing in multimode quantum optics, with applications ranging from quantum communication, metrology, and computation.","lang":"eng"}],"_id":"21697","author":[{"first_name":"Aviv","last_name":"Karnieli","full_name":"Karnieli, Aviv"},{"full_name":"Mor, Paul-Alexis","last_name":"Mor","first_name":"Paul-Alexis"},{"full_name":"Roques-Carmes, Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","first_name":"Charles","last_name":"Roques-Carmes"},{"first_name":"Eran","last_name":"Lustig","full_name":"Lustig, Eran"},{"first_name":"Jamison","last_name":"Sloan","full_name":"Sloan, Jamison"},{"full_name":"Vučković, Jelena","last_name":"Vučković","first_name":"Jelena"},{"full_name":"Miller, David A. B.","first_name":"David A. B.","last_name":"Miller"},{"full_name":"Fan, Shanhui","first_name":"Shanhui","last_name":"Fan"}],"publication_status":"submitted","month":"09","OA_type":"green","date_published":"2025-09-20T00:00:00Z","doi":"10.48550/arXiv.2509.16753","oa":1,"status":"public","article_processing_charge":"No","arxiv":1,"fulldoi":"https://doi.org/10.48550/arXiv.2509.16753","article_number":"2509.16753"},{"abstract":[{"text":"Consider a quadratic polynomial Q(ξ1, . . . , ξn) of independent Rademacher random variables ξ1, . . . , ξn. To what extent can Q(ξ1, . . . , ξn) concentrate on a single value? This quadratic version of the classical Littlewood–Offord problem was popularised by Costello, Tao and Vu in their study of symmetric random matrices. In this paper, we obtain an essentially optimal bound for this problem, as conjectured by Nguyen and Vu. Specifically, if Q(ξ1, . . . , ξn) ‘robustly depends on at least m of the ξi’ in the sense that there is no way to pin down the value of Q(ξ1, . . . , ξn) by fixing values for fewer than m of the variables ξi, then we have Pr[Q(ξ1, . . . , ξn) = 0] ≤ O(1/√m). This also implies a similar result in the case where ξ1, . . . , ξn have arbitrary distributions. Our proof combines a number of ideas that may be of independent interest, including an inductive decoupling scheme that reduces quadratic anticoncentration problems\r\nto high-dimensional linear anticoncentration problems. Also, one application of our main result is the resolution of a conjecture of Alon, Hefetz, Krivelevich and Tyomkyn related to graph inducibility. ","lang":"eng"}],"_id":"21706","acknowledgement":"We would like to thank the anonymous referee for a number of helpful comments and suggestions. Matthew Kwan was supported by ERC Starting Grant “RANDSTRUCT” No. 101076777. Lisa Sauermann was supported in part by NSF Award DMS-2100157 and a Sloan Research Fellowship, and in part by the DFG Heisenberg Program.","file_date_updated":"2026-05-04T09:41:25Z","has_accepted_license":"1","date_published":"2025-12-01T00:00:00Z","department":[{"_id":"MaKw"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Resolution of the quadratic Littlewood–Offord problem","day":"01","issue":"12","scopus_import":"1","date_created":"2026-04-12T22:01:48Z","citation":{"mla":"Kwan, Matthew Alan, and Lisa Sauermann. “Resolution of the Quadratic Littlewood–Offord Problem.” <i>Compositio Mathematica</i>, vol. 161, no. 12, Cambridge University Press, 2025, pp. 3089–139, doi:<a href=\"https://doi.org/10.1112/S0010437X25102789\">10.1112/S0010437X25102789</a>.","short":"M.A. Kwan, L. Sauermann, Compositio Mathematica 161 (2025) 3089–3139.","ieee":"M. A. Kwan and L. Sauermann, “Resolution of the quadratic Littlewood–Offord problem,” <i>Compositio Mathematica</i>, vol. 161, no. 12. Cambridge University Press, pp. 3089–3139, 2025.","apa":"Kwan, M. A., &#38; Sauermann, L. (2025). Resolution of the quadratic Littlewood–Offord problem. <i>Compositio Mathematica</i>. Cambridge University Press. <a href=\"https://doi.org/10.1112/S0010437X25102789\">https://doi.org/10.1112/S0010437X25102789</a>","chicago":"Kwan, Matthew Alan, and Lisa Sauermann. “Resolution of the Quadratic Littlewood–Offord Problem.” <i>Compositio Mathematica</i>. Cambridge University Press, 2025. <a href=\"https://doi.org/10.1112/S0010437X25102789\">https://doi.org/10.1112/S0010437X25102789</a>.","ama":"Kwan MA, Sauermann L. Resolution of the quadratic Littlewood–Offord problem. <i>Compositio Mathematica</i>. 2025;161(12):3089-3139. doi:<a href=\"https://doi.org/10.1112/S0010437X25102789\">10.1112/S0010437X25102789</a>","ista":"Kwan MA, Sauermann L. 2025. Resolution of the quadratic Littlewood–Offord problem. Compositio Mathematica. 161(12), 3089–3139."},"type":"journal_article","author":[{"full_name":"Kwan, Matthew Alan","last_name":"Kwan","first_name":"Matthew Alan","orcid":"0000-0002-4003-7567","id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3"},{"last_name":"Sauermann","first_name":"Lisa","full_name":"Sauermann, Lisa"}],"project":[{"name":"Randomness and structure in combinatorics","grant_number":"101076777","_id":"bd95085b-d553-11ed-ba76-e55d3349be45"}],"language":[{"iso":"eng"}],"OA_type":"hybrid","publication_status":"published","intvolume":"       161","article_type":"original","month":"12","ddc":["510"],"doi":"10.1112/S0010437X25102789","corr_author":"1","fulldoi":"https://doi.org/10.1112/S0010437X25102789","article_processing_charge":"Yes (via OA deal)","arxiv":1,"PlanS_conform":"1","oa":1,"publication_identifier":{"eissn":["1570-5846"],"issn":["0010-437X"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publisher":"Cambridge University Press","publication":"Compositio Mathematica","OA_place":"publisher","date_updated":"2026-05-04T09:42:57Z","quality_controlled":"1","oa_version":"Published Version","file":[{"date_created":"2026-05-04T09:41:25Z","file_name":"2025_CompositioMath_Kwan.pdf","access_level":"open_access","creator":"dernst","content_type":"application/pdf","relation":"main_file","checksum":"bd3415bb435da9d0b39f6f9a18c61abb","file_id":"21787","success":1,"file_size":858727,"date_updated":"2026-05-04T09:41:25Z"}],"volume":161,"external_id":{"arxiv":["2312.13826"]},"page":"3089-3139","year":"2025"},{"PlanS_conform":"1","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"oa":1,"fulldoi":"https://doi.org/10.3847/1538-4357/ae1ca7","arxiv":1,"article_processing_charge":"Yes","doi":"10.3847/1538-4357/ae1ca7","OA_type":"gold","ddc":["520"],"intvolume":"       996","month":"12","publication_status":"published","article_type":"original","language":[{"iso":"eng"}],"author":[{"full_name":"Lee, Max E.","first_name":"Max E.","last_name":"Lee"},{"id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","first_name":"Zoltán","orcid":"0000-0003-3633-5403","full_name":"Haiman, Zoltán"},{"full_name":"Pandey, Shivam","first_name":"Shivam","last_name":"Pandey"},{"full_name":"Genel, Shy","last_name":"Genel","first_name":"Shy"}],"year":"2025","volume":996,"external_id":{"arxiv":["2504.12460"]},"file":[{"date_updated":"2026-04-13T08:20:16Z","file_size":4122087,"success":1,"checksum":"0d8fa05617420230eac39944b36839e9","file_id":"21732","content_type":"application/pdf","creator":"dernst","relation":"main_file","access_level":"open_access","file_name":"2025_AstrophysicalJournal_Lee.pdf","date_created":"2026-04-13T08:20:16Z"}],"OA_place":"publisher","date_updated":"2026-04-13T08:30:52Z","quality_controlled":"1","oa_version":"Published Version","publication":"The Astrophysical Journal","publisher":"IOP Publishing","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"status":"public","article_number":"36","department":[{"_id":"ZoHa"}],"date_published":"2025-12-23T00:00:00Z","file_date_updated":"2026-04-13T08:20:16Z","has_accepted_license":"1","DOAJ_listed":"1","acknowledgement":"We thank Fulvio Ferlito, Ana Maria Delgado, and Ken Osato for helpful conversations during this work. M.E.L. is supported by NSF grant DGE-2036197. Z.H. acknowledges financial support from NASA ATP grant 80NSSC24K1093. The Flatiron Institute is supported by the Simons Foundation.","abstract":[{"lang":"eng","text":"The next generation of weak-gravitational-lensing surveys has the potential to place stringent constraints on cosmological parameters. However, their analysis is limited by systematics such as the intrinsic alignments of galaxies, which alter weak-lensing convergence and can lead to biases in cosmological parameter estimations. For the first time, in this work, we investigate the impact of intrinsic alignments on non-Gaussian statistics of the weak-lensing field using galaxy shapes derived from the IllustrisTNG hydrodynamical simulation. We create two catalogs of ray-traced convergence maps: one that includes the measured intrinsic shape of each galaxy and another where all galaxies are randomly rotated to eliminate intrinsic alignments. We compare a range of weak-lensing statistics between the two catalogs, including the shear–shear correlation function, the map-level angular power spectrum, one-point, peak count, and minimum distribution functions, and Minkowski functionals. For each statistic, we assess the level of statistical distinguishability between catalogs for a set of future survey angular areas. Our results reveal strong small-scale correlation in the alignment of galaxies and statistically significant boosts in weak-lensing convergence in both positive and negative directions for high-significance peaks and minima, respectively. We note that our analysis is at a fixed number density of  ˜ 5 arcmin^-2, drawn from a single realization of initial conditions, and does not include observational uncertainties or supersample covariance contributions. Weak-lensing analyses utilizing non-Gaussian statistics must account for intrinsic alignments to avoid significantly compromised cosmological inferences."}],"_id":"21724","type":"journal_article","citation":{"ama":"Lee ME, Haiman Z, Pandey S, Genel S. The effect of intrinsic alignments on weak-lensing statistics in hydrodynamical simulations. <i>The Astrophysical Journal</i>. 2025;996(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae1ca7\">10.3847/1538-4357/ae1ca7</a>","chicago":"Lee, Max E., Zoltán Haiman, Shivam Pandey, and Shy Genel. “The Effect of Intrinsic Alignments on Weak-Lensing Statistics in Hydrodynamical Simulations.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/ae1ca7\">https://doi.org/10.3847/1538-4357/ae1ca7</a>.","ista":"Lee ME, Haiman Z, Pandey S, Genel S. 2025. The effect of intrinsic alignments on weak-lensing statistics in hydrodynamical simulations. The Astrophysical Journal. 996(1), 36.","mla":"Lee, Max E., et al. “The Effect of Intrinsic Alignments on Weak-Lensing Statistics in Hydrodynamical Simulations.” <i>The Astrophysical Journal</i>, vol. 996, no. 1, 36, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae1ca7\">10.3847/1538-4357/ae1ca7</a>.","apa":"Lee, M. E., Haiman, Z., Pandey, S., &#38; Genel, S. (2025). The effect of intrinsic alignments on weak-lensing statistics in hydrodynamical simulations. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae1ca7\">https://doi.org/10.3847/1538-4357/ae1ca7</a>","short":"M.E. Lee, Z. Haiman, S. Pandey, S. Genel, The Astrophysical Journal 996 (2025).","ieee":"M. E. Lee, Z. Haiman, S. Pandey, and S. Genel, “The effect of intrinsic alignments on weak-lensing statistics in hydrodynamical simulations,” <i>The Astrophysical Journal</i>, vol. 996, no. 1. IOP Publishing, 2025."},"date_created":"2026-04-12T22:01:52Z","scopus_import":"1","issue":"1","title":"The effect of intrinsic alignments on weak-lensing statistics in hydrodynamical simulations","day":"23","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"author":[{"full_name":"Rinaldi, Pierluigi","first_name":"Pierluigi","last_name":"Rinaldi"},{"first_name":"Pablo G.","last_name":"Pérez-González","full_name":"Pérez-González, Pablo G."},{"first_name":"George H.","last_name":"Rieke","full_name":"Rieke, George H."},{"full_name":"Lyu, Jianwei","first_name":"Jianwei","last_name":"Lyu"},{"full_name":"D’Eugenio, Francesco","first_name":"Francesco","last_name":"D’Eugenio"},{"last_name":"Wu","first_name":"Zihao","full_name":"Wu, Zihao"},{"last_name":"Carniani","first_name":"Stefano","full_name":"Carniani, Stefano"},{"full_name":"Looser, Tobias J.","first_name":"Tobias J.","last_name":"Looser"},{"full_name":"Shivaei, Irene","first_name":"Irene","last_name":"Shivaei"},{"first_name":"Leindert A.","last_name":"Boogaard","full_name":"Boogaard, Leindert A."},{"first_name":"Tanio","last_name":"Diaz-Santos","full_name":"Diaz-Santos, Tanio"},{"last_name":"Colina","first_name":"Luis","full_name":"Colina, Luis"},{"full_name":"Östlin, Göran","first_name":"Göran","last_name":"Östlin"},{"full_name":"Alberts, Stacey","last_name":"Alberts","first_name":"Stacey"},{"full_name":"Álvarez-Márquez, Javier","last_name":"Álvarez-Márquez","first_name":"Javier"},{"full_name":"Annuziatella, Marianna","last_name":"Annuziatella","first_name":"Marianna"},{"first_name":"Manuel","last_name":"Aravena","full_name":"Aravena, Manuel"},{"full_name":"Bhatawdekar, Rachana","last_name":"Bhatawdekar","first_name":"Rachana"},{"first_name":"Andrew J.","last_name":"Bunker","full_name":"Bunker, Andrew J."},{"first_name":"Karina I.","last_name":"Caputi","full_name":"Caputi, Karina I."},{"full_name":"Charlot, Stéphane","first_name":"Stéphane","last_name":"Charlot"},{"last_name":"Crespo Gómez","first_name":"Alejandro","full_name":"Crespo Gómez, Alejandro"},{"full_name":"Curti, Mirko","last_name":"Curti","first_name":"Mirko"},{"full_name":"Eckart, Andreas","first_name":"Andreas","last_name":"Eckart"},{"full_name":"Gillman, Steven","last_name":"Gillman","first_name":"Steven"},{"last_name":"Hainline","first_name":"Kevin","full_name":"Hainline, Kevin"},{"full_name":"Kumari, Nimisha","first_name":"Nimisha","last_name":"Kumari"},{"first_name":"Jens","last_name":"Hjorth","full_name":"Hjorth, Jens"},{"full_name":"Iani, Edoardo","first_name":"Edoardo","last_name":"Iani","orcid":"0000-0001-8386-3546","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a"},{"first_name":"Hanae","last_name":"Inami","full_name":"Inami, Hanae"},{"full_name":"Ji, Zhiyuan","first_name":"Zhiyuan","last_name":"Ji"},{"full_name":"Johnson, Benjamin D.","first_name":"Benjamin D.","last_name":"Johnson"},{"last_name":"Jones","first_name":"Gareth C.","full_name":"Jones, Gareth C."},{"full_name":"Labiano, Álvaro","first_name":"Álvaro","last_name":"Labiano"},{"first_name":"Roberto","last_name":"Maiolino","full_name":"Maiolino, Roberto"},{"first_name":"Jens","last_name":"Melinder","full_name":"Melinder, Jens"},{"full_name":"Moutard, Thibaud","first_name":"Thibaud","last_name":"Moutard"},{"last_name":"Peissker","first_name":"Florian","full_name":"Peissker, Florian"},{"first_name":"Marcia","last_name":"Rieke","full_name":"Rieke, Marcia"},{"full_name":"Robertson, Brant","last_name":"Robertson","first_name":"Brant"},{"full_name":"Scholtz, Jan","first_name":"Jan","last_name":"Scholtz"},{"last_name":"Tacchella","first_name":"Sandro","full_name":"Tacchella, Sandro"},{"first_name":"Paul P.","last_name":"Van Der Werf","full_name":"Van Der Werf, Paul P."},{"full_name":"Walter, Fabian","first_name":"Fabian","last_name":"Walter"},{"last_name":"Williams","first_name":"Christina C.","full_name":"Williams, Christina C."},{"last_name":"Willott","first_name":"Chris","full_name":"Willott, Chris"},{"full_name":"Witstok, Joris","last_name":"Witstok","first_name":"Joris"},{"last_name":"Übler","first_name":"Hannah","full_name":"Übler, Hannah"},{"last_name":"Zhu","first_name":"Yongda","full_name":"Zhu, Yongda"}],"language":[{"iso":"eng"}],"OA_type":"gold","article_type":"original","ddc":["520"],"month":"11","intvolume":"       994","publication_status":"published","doi":"10.3847/1538-4357/ae089c","fulldoi":"https://doi.org/10.3847/1538-4357/ae089c","article_processing_charge":"Yes","PlanS_conform":"1","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"The Astrophysical Journal","publisher":"IOP Publishing","date_updated":"2026-04-13T07:54:11Z","quality_controlled":"1","OA_place":"publisher","oa_version":"Published Version","file":[{"date_updated":"2026-04-13T07:53:00Z","file_id":"21731","checksum":"5d13b0ad3e9f56cbe29c5de0ba5757c8","success":1,"file_size":10298729,"file_name":"2025_AstrophysicalJournal_Rinaldi.pdf","access_level":"open_access","creator":"dernst","content_type":"application/pdf","relation":"main_file","date_created":"2026-04-13T07:53:00Z"}],"volume":994,"year":"2025","_id":"21727","abstract":[{"lang":"eng","text":"We present a comprehensive analysis of the MIRI Extremely Red Object Virgil, a Lyα emitter at zspec = 6.6379 ± 0.0035 with the photometric properties of a Little Red Dot. Leveraging new JWST/MIRI imaging from the MIDIS and PAHSPECS programs, we confirm Virgil’s extraordinary nature among galaxies in JADES/GOODS-South, exhibiting a strikingly red NIRCam-to-MIRI color (F444W–F1500W = 2.84 ± 0.04 mag). Deep NIRSpec/PRISM spectroscopy from the OASIS program offers key insights into the host galaxy, revealing properties of an average star-forming galaxy during Cosmic Reionization, such as a subsolar metallicity, low-to-moderate dust content, and a relatively high ionization parameter and electron temperature. By estimating the star formation rate of Virgil from UV and Hα, we find evidence that the galaxy is either entering or fading out of a bursty episode. Although line-ratio diagnostics employed at high z would classify Virgil as an active galactic nucleus (AGN), this classification becomes ambiguous once redshift evolution is considered. Nonetheless, Virgil occupies the same parameter space as recently confirmed AGNs at similar redshifts. The new deep MIRI data at 15 μm reinforce the AGN nature of Virgil, as inferred from multiple spectral energy distribution (SED) fitting codes. Virgil’s rising infrared SED and UV excess resemble those of Dust-Obscured Galaxies (DOGs) studied with Spitzer at Cosmic Noon, particularly blue-excess HotDOGs. Our results highlight the need for a multiwavelength approach incorporating MIRI to uncover such extreme sources at z ≳ 6 and to shed light on the interplay between galaxy evolution and early black hole growth during Cosmic Reionization."}],"acknowledgement":"The authors are deeply grateful to Antonello Calabrò for valuable insights on CLOUDY and pyCloudy, and for publicly sharing their SFG and AGN models, which were used as a reference to verify the consistency of our photoionization models. The authors also thank Adam Carnall for insightful input on bagpipes and for assistance with the implementation of the two-population model adopted in this work. Finally, they also thank Camilla Pacifici, Vasily Kokorev, and Cristian Vignali for their insightful discussions.\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with JWST programs GTO #1180, GO #1210, GTO#1283, GO #1963, GO #1895, GO# 3215, and GO#6511.\r\n\r\nThe authors acknowledge the FRESCO, JEMS, and #3215 teams led by co-PIs P. Oesch, C. C. Williams, M. Maseda, D. Eisenstein, and R. Maiolino for developing their observing program with a zero-exclusive-access period. Processing for the JADES NIRCam data release was performed on the lux cluster at the University of California, Santa Cruz, funded by NSF MRI grant AST 1828315. Also based on observations made with the NASA/ESA Hubble Space Telescope obtained from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 526555. The data presented in this article were obtained from MAST at the Space Telescope Science Institute. The specific observations analyzed can be accessed via doi: 10.17909/1rq3-8048 P. Oesch & D. Magee (2023), C. Williams et al. (2023), G. Illingworth (2015), and M. Rieke et al. (2023).\r\n\r\nA.J.B. acknowledges funding from the “FirstGalaxies” Advanced Grant from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No. 789056).\r\n\r\nP.G.P.-G. acknowledges support from grant PID2022-139567NB-I00 funded by the Spanish Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033, FEDER, UE.\r\n\r\nB.E.R. acknowledges support from the NIRCam Science Team contract to the University of Arizona, NAS5-02015, and JWST Program 3215.\r\n\r\nS.T. acknowledges support by the Royal Society Research Grant G125142.\r\n\r\nThe research of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation.\r\n\r\nJ.W. gratefully acknowledges support from the Cosmic Dawn Center through the DAWN Fellowship. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant No. 140.\r\n\r\nY.Z., Z.J., and P.L. gratefully acknowledge the JWST/NIRCam contract to the University of Arizona NAS5-02015.\r\n\r\nThe work of G.H.R. and P.L. was also supported by grant 80NSSC18K0555, from the NASA Goddard Space Flight Center to the University of Arizona.\r\n\r\nH.Ü. acknowledges funding by the European Union (ERC APEX, 101164796). Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.\r\n\r\nG.C.J. acknowledges support by the Science and Technology Facilities Council (STFC), ERC Advanced grant 695671 “QUENCH.”\r\n\r\nA.C.G. acknowledges support by JWST contract B0215/JWST-GO-02926.\r\n\r\nG.O. acknowledges support from the Swedish National Space Agency (SNSA).\r\n\r\nH.I. acknowledges support from JSPS KAKENHI grant No. JP21H01129.\r\n\r\nM.A. gratefully acknowledges support from ANID Basal Project FB210003 and ANID MILENIO NCN2024_112.\r\n\r\nT.D.S. acknowledges the research project was supported by the Hellenic Foundation for Research and Innovation (HFRI) under the “2nd Call for HFRI Research Projects to Support Faculty Members and Researchers” (project No.: 03382).\r\n\r\nR.M. acknowledges support by the Science and Technology Facilities Council (STFC), by the ERC through Advanced grant 695671 “QUENCH,” and by the UKRI Frontier Research grant RISEandFALL. R.M. also acknowledges funding from a research professorship from the Royal Society.\r\n\r\nI.S. acknowledges funding from the Atraccíon de Talento grant No. 2022-T1/TIC-20472 of the Comunidad de Madrid, Spain, and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant No. 101117541, DistantDust).\r\n\r\nK.I.C. acknowledges funding from the Dutch Research Council (NWO) through the award of the Vici grant VI.C.212.036.\r\n\r\nFacilities: HST - Hubble Space Telescope satellite, JWST. -\r\n\r\nSoftware: Astropy (Astropy Collaboration et al. 2022), Bagpipes (A. C. Carnall et al. 2019), MSAEXP (G. Brammer 2023) NumPy (C. R. Harris et al. 2020), pandas (The pandas development team 2024) Photutils (L. Bradley et al. 2016), TOPCAT (M. Taylor 2022).","DOAJ_listed":"1","has_accepted_license":"1","file_date_updated":"2026-04-13T07:53:00Z","date_published":"2025-11-20T00:00:00Z","department":[{"_id":"JoMa"}],"article_number":"86","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization","day":"20","issue":"1","scopus_import":"1","date_created":"2026-04-12T22:01:53Z","citation":{"chicago":"Rinaldi, Pierluigi, Pablo G. Pérez-González, George H. Rieke, Jianwei Lyu, Francesco D’Eugenio, Zihao Wu, Stefano Carniani, et al. “Deciphering the Nature of Virgil: An Obscured Active Galactic Nucleus Lurking within an Apparently Normal Lyα Emitter during Cosmic Reionization.” <i>The Astrophysical Journal</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/1538-4357/ae089c\">https://doi.org/10.3847/1538-4357/ae089c</a>.","ama":"Rinaldi P, Pérez-González PG, Rieke GH, et al. Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. <i>The Astrophysical Journal</i>. 2025;994(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae089c\">10.3847/1538-4357/ae089c</a>","ista":"Rinaldi P, Pérez-González PG, Rieke GH, Lyu J, D’Eugenio F, Wu Z, Carniani S, Looser TJ, Shivaei I, Boogaard LA, Diaz-Santos T, Colina L, Östlin G, Alberts S, Álvarez-Márquez J, Annuziatella M, Aravena M, Bhatawdekar R, Bunker AJ, Caputi KI, Charlot S, Crespo Gómez A, Curti M, Eckart A, Gillman S, Hainline K, Kumari N, Hjorth J, Iani E, Inami H, Ji Z, Johnson BD, Jones GC, Labiano Á, Maiolino R, Melinder J, Moutard T, Peissker F, Rieke M, Robertson B, Scholtz J, Tacchella S, Van Der Werf PP, Walter F, Williams CC, Willott C, Witstok J, Übler H, Zhu Y. 2025. Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. The Astrophysical Journal. 994(1), 86.","mla":"Rinaldi, Pierluigi, et al. “Deciphering the Nature of Virgil: An Obscured Active Galactic Nucleus Lurking within an Apparently Normal Lyα Emitter during Cosmic Reionization.” <i>The Astrophysical Journal</i>, vol. 994, no. 1, 86, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae089c\">10.3847/1538-4357/ae089c</a>.","ieee":"P. Rinaldi <i>et al.</i>, “Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization,” <i>The Astrophysical Journal</i>, vol. 994, no. 1. IOP Publishing, 2025.","short":"P. Rinaldi, P.G. Pérez-González, G.H. Rieke, J. Lyu, F. D’Eugenio, Z. Wu, S. Carniani, T.J. Looser, I. Shivaei, L.A. Boogaard, T. Diaz-Santos, L. Colina, G. Östlin, S. Alberts, J. Álvarez-Márquez, M. Annuziatella, M. Aravena, R. Bhatawdekar, A.J. Bunker, K.I. Caputi, S. Charlot, A. Crespo Gómez, M. Curti, A. Eckart, S. Gillman, K. Hainline, N. Kumari, J. Hjorth, E. Iani, H. Inami, Z. Ji, B.D. Johnson, G.C. Jones, Á. Labiano, R. Maiolino, J. Melinder, T. Moutard, F. Peissker, M. Rieke, B. Robertson, J. Scholtz, S. Tacchella, P.P. Van Der Werf, F. Walter, C.C. Williams, C. Willott, J. Witstok, H. Übler, Y. Zhu, The Astrophysical Journal 994 (2025).","apa":"Rinaldi, P., Pérez-González, P. G., Rieke, G. H., Lyu, J., D’Eugenio, F., Wu, Z., … Zhu, Y. (2025). Deciphering the nature of Virgil: An obscured active galactic nucleus lurking within an apparently normal Lyα emitter during cosmic reionization. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae089c\">https://doi.org/10.3847/1538-4357/ae089c</a>"},"type":"journal_article"},{"title":"Neural Certificates","publisher":"IEEE","day":"01","publication":"Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","scopus_import":"1","date_updated":"2026-05-18T08:34:15Z","oa_version":"None","date_created":"2026-05-17T22:02:11Z","citation":{"ieee":"T. A. Henzinger, “Neural Certificates,” in <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>, Timisoara, Romania, 2025.","short":"T.A. Henzinger, in:, Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing, IEEE, 2025.","apa":"Henzinger, T. A. (2025). Neural Certificates. In <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. Timisoara, Romania: IEEE. <a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">https://doi.org/10.1109/SYNASC69064.2025.00008</a>","mla":"Henzinger, Thomas A. “Neural Certificates.” <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>, IEEE, 2025, doi:<a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">10.1109/SYNASC69064.2025.00008</a>.","ista":"Henzinger TA. 2025. Neural Certificates. Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing. SYNASC: Symposium on Symbolic and Numeric Algorithms for Scientific Computing.","ama":"Henzinger TA. Neural Certificates. In: <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. IEEE; 2025. doi:<a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">10.1109/SYNASC69064.2025.00008</a>","chicago":"Henzinger, Thomas A. “Neural Certificates.” In <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. IEEE, 2025. <a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">https://doi.org/10.1109/SYNASC69064.2025.00008</a>."},"year":"2025","type":"conference","language":[{"iso":"eng"}],"author":[{"full_name":"Henzinger, Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","last_name":"Henzinger","orcid":"0000-0002-2985-7724"}],"_id":"21885","abstract":[{"text":"Symbolic datatypes have proved to be central for automated reasoning about dynamical systems. In its basic form, a symbolic datatype for a class of dynamical systems supports the representation of state and transition sets, boolean operations and emptiness checks on such sets, and the transformation of a state set by a transition set. Successful examples of symbolic datatypes include BDDs and SAT for reasoning about finitestate systems, as well as polyhedra and SMT for reasoning about discrete dynamical systems over multidimensional realvalued state spaces. Most automated verification engines are based on such symbolic datatypes.","lang":"eng"}],"OA_type":"closed access","publication_status":"published","month":"10","conference":{"location":"Timisoara, Romania","end_date":"2025-09-25","start_date":"2025-09-22","name":"SYNASC: Symposium on Symbolic and Numeric Algorithms for Scientific Computing"},"department":[{"_id":"ToHe"}],"doi":"10.1109/SYNASC69064.2025.00008","date_published":"2025-10-01T00:00:00Z","status":"public","publication_identifier":{"eissn":["2470-881X"],"eisbn":["9798331590116"]},"corr_author":"1","fulldoi":"https://doi.org/10.1109/SYNASC69064.2025.00008","article_processing_charge":"No"},{"has_accepted_license":"1","_id":"21912","abstract":[{"text":"The mammalian fatty acid synthase (FASN) enzyme is a dynamic multienzyme that belongs to the megasynthase family. In mammals, a single gene encodes six catalytically active domains and a flexibly tethered acyl carrier protein (ACP) domain that shuttles intermediates between active sites for fatty acid biosynthesis1. FASN is an essential enzyme in mammalian development through the role that fatty acids have in membrane formation, energy storage, cell signalling and protein modifications. Thus, FASN is a promising target for treatment of a large variety of diseases including cancer, metabolic dysfunction-associated fatty liver disease, and viral and parasite infections2,3. The multi-faceted mechanism of FASN and the dynamic nature of the protein, in particular of the ACP, have made it challenging to understand at the molecular level. Here we report cryo-electron microscopy structures of human FASN in a multitude of conformational states with NADPH and NADP+ plus acetoacetyl-CoA present, including structures with the ACP stalled at the dehydratase (DH) and enoyl-reductase (ER) domains. We show that FASN activity in vitro and de novo lipogenesis in cells is inhibited by mutations at the ACP–DH and ACP–ER interfaces. Together, these studies provide new molecular insights into the dynamic nature of FASN and the ACP shuttling mechanism, with implications for developing improved FASN-targeted therapeutics.","lang":"eng"}],"status":"public","date_published":"2025-05-08T00:00:00Z","issue":"8062","title":"Snapshots of acyl carrier protein shuttling in human fatty acid synthase","day":"08","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","date_created":"2026-05-24T08:25:19Z","citation":{"ista":"Schultz K, Costa-Pinheiro P, Gardner L, Pinheiro LV, Ramirez-Solis J, Gardner SM, Wellen KE, Marmorstein R. 2025. Snapshots of acyl carrier protein shuttling in human fatty acid synthase. Nature. 641(8062), 520–528.","chicago":"Schultz, Kollin, Pedro Costa-Pinheiro, Lauren Gardner, Laura V. Pinheiro, Julio Ramirez-Solis, Sarah M. Gardner, Kathryn E. Wellen, and Ronen Marmorstein. “Snapshots of Acyl Carrier Protein Shuttling in Human Fatty Acid Synthase.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-025-08587-x\">https://doi.org/10.1038/s41586-025-08587-x</a>.","ama":"Schultz K, Costa-Pinheiro P, Gardner L, et al. Snapshots of acyl carrier protein shuttling in human fatty acid synthase. <i>Nature</i>. 2025;641(8062):520-528. doi:<a href=\"https://doi.org/10.1038/s41586-025-08587-x\">10.1038/s41586-025-08587-x</a>","ieee":"K. Schultz <i>et al.</i>, “Snapshots of acyl carrier protein shuttling in human fatty acid synthase,” <i>Nature</i>, vol. 641, no. 8062. Springer Nature, pp. 520–528, 2025.","apa":"Schultz, K., Costa-Pinheiro, P., Gardner, L., Pinheiro, L. V., Ramirez-Solis, J., Gardner, S. M., … Marmorstein, R. (2025). Snapshots of acyl carrier protein shuttling in human fatty acid synthase. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-08587-x\">https://doi.org/10.1038/s41586-025-08587-x</a>","short":"K. Schultz, P. Costa-Pinheiro, L. Gardner, L.V. Pinheiro, J. Ramirez-Solis, S.M. Gardner, K.E. Wellen, R. Marmorstein, Nature 641 (2025) 520–528.","mla":"Schultz, Kollin, et al. “Snapshots of Acyl Carrier Protein Shuttling in Human Fatty Acid Synthase.” <i>Nature</i>, vol. 641, no. 8062, Springer Nature, 2025, pp. 520–28, doi:<a href=\"https://doi.org/10.1038/s41586-025-08587-x\">10.1038/s41586-025-08587-x</a>."},"OA_type":"hybrid","publication_status":"published","ddc":["572"],"article_type":"original","month":"05","intvolume":"       641","language":[{"iso":"eng"}],"author":[{"full_name":"Schultz, Kollin","first_name":"Kollin","last_name":"Schultz"},{"last_name":"Costa-Pinheiro","first_name":"Pedro","full_name":"Costa-Pinheiro, Pedro"},{"first_name":"Lauren","last_name":"Gardner","orcid":"0009-0000-5733-1546","id":"f9dedd98-6d15-11f0-88a5-a7b4143fdec5","full_name":"Gardner, Lauren"},{"last_name":"Pinheiro","first_name":"Laura V.","full_name":"Pinheiro, Laura V."},{"first_name":"Julio","last_name":"Ramirez-Solis","full_name":"Ramirez-Solis, Julio"},{"last_name":"Gardner","first_name":"Sarah M.","full_name":"Gardner, Sarah M."},{"full_name":"Wellen, Kathryn E.","first_name":"Kathryn E.","last_name":"Wellen"},{"last_name":"Marmorstein","first_name":"Ronen","full_name":"Marmorstein, Ronen"}],"pmid":1,"publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"oa":1,"fulldoi":"https://doi.org/10.1038/s41586-025-08587-x","article_processing_charge":"Yes (in subscription journal)","doi":"10.1038/s41586-025-08587-x","OA_place":"publisher","quality_controlled":"1","date_updated":"2026-06-02T14:57:52Z","oa_version":"Published Version","extern":"1","publisher":"Springer Nature","publication":"Nature","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"year":"2025","page":"520-528","volume":641,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41586-025-08587-x"}],"external_id":{"pmid":["39979457 "]}},{"language":[{"iso":"eng"}],"project":[{"name":"Development and Evolution of Tetrapod Motor Circuits","grant_number":"101041551","_id":"ebb66355-77a9-11ec-83b8-b8ac210a4dae"},{"_id":"907b765e-16d5-11f0-9cad-fef108a945b1","name":"A Tale of Two Circuits: Rostrocaudal spinal cord patterning during the swim-to-limb transition of Xenopus metamorphosis","grant_number":"27229"}],"_id":"21920","abstract":[{"lang":"eng","text":"Vertebrates display remarkable diversity of sensorimotor behaviors, each adapted to distinct ecological and survival demands. This diversity raises fundamental questions about the evolutionary origin of motor control: do conserved spinal circuits underlie these behaviors, and how have they diverged across species. Recent studies detail spinal cell-type architecture in mammals but comparable, high-resolution atlases of the non-mammalian spinal cord are lacking. Here, we compare spinal cord cell types between fish, frogs, mice and humans, spanning ∼450 million years of evolution. Across species, we define highly conserved programs of cell type specification that segregate spinal neurons into nearly identical cardinal classes during development. This contrasts with adult stages, when spinal cell-type composition selectively diverges for excitatory neuron subpopulations. Using spatial transcriptomics, we localize this species divergence to the superficial, dorsal spinal cord, where variant neuropeptide expression defines mammalian-specific cell types. The most dorsal spinal cord thus emerges as a recently evolved hub for sensory integration in mammals, a neospinal cord analogous to the neocortex.</jats:p>"}],"author":[{"last_name":"Ignatyev","first_name":"Yuri","full_name":"Ignatyev, Yuri"},{"last_name":"Papadopoulos","first_name":"Stavros","id":"40606b92-f128-11eb-9611-bf66a98cfa5c","full_name":"Papadopoulos, Stavros"},{"full_name":"Soretić, Mateja","first_name":"Mateja","last_name":"Soretić"},{"full_name":"Yeung, Jake","last_name":"Yeung","first_name":"Jake","orcid":"0000-0003-1732-1559","id":"123012b2-db30-11eb-b4d8-a35840c0551b"},{"full_name":"Lin, Tzi-Yang","last_name":"Lin","first_name":"Tzi-Yang"},{"last_name":"Tanaka","first_name":"Elly M","full_name":"Tanaka, Elly M"},{"last_name":"Peshkin","first_name":"Leonid","full_name":"Peshkin, Leonid"},{"full_name":"Levine, Ariel J","first_name":"Ariel J","last_name":"Levine"},{"full_name":"Gabitto, Mariano I","last_name":"Gabitto","first_name":"Mariano I"},{"last_name":"Sweeney","first_name":"Lora Beatrice Jaeger","orcid":"0000-0001-9242-5601","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","full_name":"Sweeney, Lora Beatrice Jaeger"}],"publication_status":"submitted","month":"10","OA_type":"green","acknowledgement":"We would like to thank the members of the Sweeney Lab for discussion and support; Andrey\r\nBydanov for technical assistance with single-cell sequencing processing; and Jay Bikoff,\r\nNikos Konstantinides, Maria Tosches, and Graziana Gatto for comments on the manuscript. \r\nThis research was supported by: Horizon Europe ERC Starting Grant 101041551 (L.B.S,\r\nY.I., S.P.); Special Research Program (SFB) of the Austrian Science Fund (FWF) F7814-B\r\n(L.B.S., S.P., E.M.T); Austrian Science Fund (FWF) 10.55776/COE16 (L.B.S., Y.I., E.M.T.);\r\nAustrian Academy of Sciences DOC Fellowship 27229 (S.P.); ERC Advanced Grant 742046\r\n(E.M.T.); NIH award R24 OD031956 (L.P.); and in part by the Intramural Research\r\nProgram of the National Institutes of Health (NIH) through 1ZIA NS003153 to A.J.L.\r\nThe contributions of the NIH author are considered Works of the United States\r\nGovernment. The findings and conclusions presented in this paper are those of\r\nthe authors and do not necessarily reflect the views of the NIH or the U.S. Department\r\nof Health and Human Services. ","department":[{"_id":"LoSw"},{"_id":"ScienComp"}],"doi":"10.1101/2025.10.09.680955","date_published":"2025-10-11T00:00:00Z","oa":1,"status":"public","article_processing_charge":"No","fulldoi":"https://doi.org/10.1101/2025.10.09.680955","corr_author":"1","publication":"bioRxiv","day":"11","title":"Innovations in spinal cord cell type heterogeneity across vertebrate evolution","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"oa_version":"Preprint","OA_place":"repository","date_updated":"2026-05-27T07:25:41Z","main_file_link":[{"url":"https://doi.org/10.1101/2025.10.09.680955","open_access":"1"}],"date_created":"2026-05-27T06:54:04Z","citation":{"ama":"Ignatyev Y, Papadopoulos S, Soretić M, et al. Innovations in spinal cord cell type heterogeneity across vertebrate evolution. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.10.09.680955\">10.1101/2025.10.09.680955</a>","chicago":"Ignatyev, Yuri, Stavros Papadopoulos, Mateja Soretić, Jake Yeung, Tzi-Yang Lin, Elly M Tanaka, Leonid Peshkin, Ariel J Levine, Mariano I Gabitto, and Lora B. Sweeney. “Innovations in Spinal Cord Cell Type Heterogeneity across Vertebrate Evolution.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.10.09.680955\">https://doi.org/10.1101/2025.10.09.680955</a>.","ista":"Ignatyev Y, Papadopoulos S, Soretić M, Yeung J, Lin T-Y, Tanaka EM, Peshkin L, Levine AJ, Gabitto MI, Sweeney LB. Innovations in spinal cord cell type heterogeneity across vertebrate evolution. bioRxiv, <a href=\"https://doi.org/10.1101/2025.10.09.680955\">10.1101/2025.10.09.680955</a>.","short":"Y. Ignatyev, S. Papadopoulos, M. Soretić, J. Yeung, T.-Y. Lin, E.M. Tanaka, L. Peshkin, A.J. Levine, M.I. Gabitto, L.B. Sweeney, BioRxiv (n.d.).","ieee":"Y. Ignatyev <i>et al.</i>, “Innovations in spinal cord cell type heterogeneity across vertebrate evolution,” <i>bioRxiv</i>. .","apa":"Ignatyev, Y., Papadopoulos, S., Soretić, M., Yeung, J., Lin, T.-Y., Tanaka, E. M., … Sweeney, L. B. (n.d.). Innovations in spinal cord cell type heterogeneity across vertebrate evolution. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.10.09.680955\">https://doi.org/10.1101/2025.10.09.680955</a>","mla":"Ignatyev, Yuri, et al. “Innovations in Spinal Cord Cell Type Heterogeneity across Vertebrate Evolution.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.10.09.680955\">10.1101/2025.10.09.680955</a>."},"year":"2025","type":"preprint"},{"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway","day":"14","type":"journal_article","citation":{"apa":"Bose, M., Suresh, V., Mishra, U., Talwar, I., Yadav, A., Biswas, S., … Tole, S. (2025). Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.101851.3\">https://doi.org/10.7554/elife.101851.3</a>","ieee":"M. Bose <i>et al.</i>, “Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway,” <i>eLife</i>, vol. 13. eLife Sciences Publications, 2025.","short":"M. Bose, V. Suresh, U. Mishra, I. Talwar, A. Yadav, S. Biswas, S. Hippenmeyer, S. Tole, ELife 13 (2025).","mla":"Bose, Mahima, et al. “Dual Role of FOXG1 in Regulating Gliogenesis in the Developing Neocortex via the FGF Signalling Pathway.” <i>ELife</i>, vol. 13, 101851, eLife Sciences Publications, 2025, doi:<a href=\"https://doi.org/10.7554/elife.101851.3\">10.7554/elife.101851.3</a>.","chicago":"Bose, Mahima, Varun Suresh, Urvi Mishra, Ishita Talwar, Anuradha Yadav, Shiona Biswas, Simon Hippenmeyer, and Shubha Tole. “Dual Role of FOXG1 in Regulating Gliogenesis in the Developing Neocortex via the FGF Signalling Pathway.” <i>ELife</i>. eLife Sciences Publications, 2025. <a href=\"https://doi.org/10.7554/elife.101851.3\">https://doi.org/10.7554/elife.101851.3</a>.","ama":"Bose M, Suresh V, Mishra U, et al. Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway. <i>eLife</i>. 2025;13. doi:<a href=\"https://doi.org/10.7554/elife.101851.3\">10.7554/elife.101851.3</a>","ista":"Bose M, Suresh V, Mishra U, Talwar I, Yadav A, Biswas S, Hippenmeyer S, Tole S. 2025. Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway. eLife. 13, 101851."},"date_created":"2023-12-06T13:07:01Z","acknowledgement":"We thank the animal house staff of the Tata Institute of Fundamental Research, Mumbai (TIFR), for their excellent support; Gordon Fishell (Harvard Medical School, USA), and Goichi Miyoshi (Gunma University, Japan) for the Foxg1 floxed mouse line; Hiroshi Kawasaki (Kanazawa University, Japan) for the plasmids pCAG-FGF8 and pCAG-sFgfr3c; Soo Kyung Lee (University at Buffalo, The State University of New York, USA) for the Foxg1lox/lox genotyping primers and protocol. We thank Deepak Modi and Vainav Patel (National Institute for Research in Reproductive and Child Health, NIRRCH, Mumbai, India) for the use of the NIRRCH FACS Facility, and the staff of the NIRRCH and TIFR FACS facilities for their assistance. We thank Denis Jabaudon (University of Geneva, Switzerland) for his critical comments on the manuscript and members of the Jabaudon lab for helpful discussions. This work was funded by the Department of Atomic Energy (DAE), Govt. of India (Project Identification no. RTI4003,\r\nDAE OM no. 1303/2/2019/R&D-II/DAE/2079). ","file_date_updated":"2025-04-03T11:19:26Z","has_accepted_license":"1","_id":"14647","abstract":[{"text":"In the developing vertebrate central nervous system, neurons and glia typically arise\r\nsequentially from common progenitors. Here, we report that the transcription factor Forkhead\r\nBox G1 (Foxg1) regulates gliogenesis in the mouse neocortex via distinct cell-autonomous roles in progenitors and postmitotic neurons that regulate different aspects of the gliogenic FGF signalling pathway. We demonstrate that loss of Foxg1 in cortical progenitors at neurogenic stages causes premature astrogliogenesis. We identify a novel FOXG1 target, the pro-gliogenic FGF pathway component Fgfr3, which is suppressed by FOXG1 cell-autonomously to maintain neurogenesis. Furthermore, FOXG1 can also suppress premature astrogliogenesis triggered by the augmentation of FGF signalling. We identify a second novel function of FOXG1 in regulating the expression of gliogenic cues in newborn neocortical upper-layer neurons. Loss of FOXG1 in postmitotic neurons non-autonomously enhances gliogenesis in the progenitors via FGF signalling. These results fit well with the model that newborn neurons secrete cues that trigger progenitors to produce the next wave of cell types, astrocytes. If FGF signalling is attenuated in Foxg1 null progenitors, they progress to oligodendrocyte production. Therefore, loss of FOXG1 transitions the progenitor to a gliogenic state, producing either astrocytes or oligodendrocytes depending on FGF signalling levels. Our results uncover how FOXG1 integrates extrinsic signalling via the FGF pathway to regulate the sequential generation of neurons, astrocytes, and oligodendrocytes in the cerebral cortex. ","lang":"eng"}],"article_number":"101851","status":"public","date_published":"2025-03-14T00:00:00Z","department":[{"_id":"SiHi"}],"date_updated":"2025-05-14T11:41:52Z","OA_place":"publisher","quality_controlled":"1","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"eLife","publisher":"eLife Sciences Publications","year":"2025","external_id":{"pmid":["40085500"]},"volume":13,"file":[{"date_updated":"2025-04-03T11:19:26Z","checksum":"64a6a6f86e24b21fe72c7a7fd6056fed","file_id":"19467","success":1,"file_size":17462771,"file_name":"2025_eLife_Bose.pdf","access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","date_created":"2025-04-03T11:19:26Z"}],"OA_type":"gold","intvolume":"        13","ddc":["570"],"publication_status":"published","article_type":"original","month":"03","author":[{"last_name":"Bose","first_name":"Mahima","full_name":"Bose, Mahima"},{"full_name":"Suresh, Varun","first_name":"Varun","last_name":"Suresh"},{"full_name":"Mishra, Urvi","last_name":"Mishra","first_name":"Urvi"},{"full_name":"Talwar, Ishita","last_name":"Talwar","first_name":"Ishita"},{"first_name":"Anuradha","last_name":"Yadav","full_name":"Yadav, Anuradha"},{"full_name":"Biswas, Shiona","last_name":"Biswas","first_name":"Shiona"},{"last_name":"Hippenmeyer","first_name":"Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"},{"last_name":"Tole","first_name":"Shubha","full_name":"Tole, Shubha"}],"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.7554/elife.101851.3","article_processing_charge":"Yes","pmid":1,"oa":1,"publication_identifier":{"eissn":["2050-084X"]},"doi":"10.7554/elife.101851.3"},{"publication":"Mathematical Programming","publisher":"Springer Nature","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"13236"}]},"oa_version":"Preprint","date_updated":"2025-09-09T12:39:58Z","OA_place":"repository","quality_controlled":"1","external_id":{"arxiv":["2301.09217"],"isi":["001176048100003"]},"volume":210,"page":"881-894","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2301.09217"}],"year":"2025","ec_funded":1,"language":[{"iso":"eng"}],"project":[{"call_identifier":"H2020","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62","grant_number":"101019564","name":"The design and evaluation of modern fully dynamic data structures"},{"_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","grant_number":"P33775","name":"Fast Algorithms for a Reactive Network Layer"}],"author":[{"first_name":"Da Wei","last_name":"Zheng","full_name":"Zheng, Da Wei"},{"full_name":"Henzinger, Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","first_name":"Monika H","orcid":"0000-0002-5008-6530"}],"month":"03","intvolume":"       210","publication_status":"published","article_type":"original","OA_type":"green","doi":"10.1007/s10107-024-02066-3","publication_identifier":{"eissn":["1436-4646"],"issn":["0025-5610"]},"oa":1,"arxiv":1,"article_processing_charge":"No","corr_author":"1","fulldoi":"https://doi.org/10.1007/s10107-024-02066-3","day":"01","title":"Multiplicative auction algorithm for approximate maximum weight bipartite matching","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"scopus_import":"1","citation":{"ista":"Zheng DW, Henzinger M. 2025. Multiplicative auction algorithm for approximate maximum weight bipartite matching. Mathematical Programming. 210, 881–894.","ama":"Zheng DW, Henzinger M. Multiplicative auction algorithm for approximate maximum weight bipartite matching. <i>Mathematical Programming</i>. 2025;210:881-894. doi:<a href=\"https://doi.org/10.1007/s10107-024-02066-3\">10.1007/s10107-024-02066-3</a>","chicago":"Zheng, Da Wei, and Monika Henzinger. “Multiplicative Auction Algorithm for Approximate Maximum Weight Bipartite Matching.” <i>Mathematical Programming</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10107-024-02066-3\">https://doi.org/10.1007/s10107-024-02066-3</a>.","apa":"Zheng, D. W., &#38; Henzinger, M. (2025). Multiplicative auction algorithm for approximate maximum weight bipartite matching. <i>Mathematical Programming</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10107-024-02066-3\">https://doi.org/10.1007/s10107-024-02066-3</a>","ieee":"D. W. Zheng and M. Henzinger, “Multiplicative auction algorithm for approximate maximum weight bipartite matching,” <i>Mathematical Programming</i>, vol. 210. Springer Nature, pp. 881–894, 2025.","short":"D.W. Zheng, M. Henzinger, Mathematical Programming 210 (2025) 881–894.","mla":"Zheng, Da Wei, and Monika Henzinger. “Multiplicative Auction Algorithm for Approximate Maximum Weight Bipartite Matching.” <i>Mathematical Programming</i>, vol. 210, Springer Nature, 2025, pp. 881–94, doi:<a href=\"https://doi.org/10.1007/s10107-024-02066-3\">10.1007/s10107-024-02066-3</a>."},"date_created":"2024-03-17T23:00:58Z","type":"journal_article","_id":"15121","abstract":[{"lang":"eng","text":"We present an auction algorithm using multiplicative instead of constant weight updates to compute a (1-E)-approximate maximum weight matching (MWM) in a bipartite graph with n vertices and m edges in time 0(mE-1), beating the running time of the fastest known approximation algorithm of Duan and Pettie [JACM ’14] that runs in 0(mE-1 log E-1). Our algorithm is very simple and it can be extended to give a dynamic data structure that maintains a (1-E)-approximate maximum weight matching under (1) one-sided vertex deletions (with incident edges) and (2) one-sided vertex insertions (with incident edges sorted by weight) to the other side. The total time time used is 0(mE-1), where m is the sum of the number of initially existing and inserted edges."}],"acknowledgement":"The first author thanks Chandra Chekuri for useful discussions about this paper. This work was done in part at the University of Vienna. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDynStruct)” and from the Austrian Science Fund (FWF) project “Fast Algorithms for a Reactive Network Layer (ReactNet)”, P 33775-N, with additional funding from the netidee SCIENCE Stiftung, 2020–2024.","department":[{"_id":"MoHe"}],"date_published":"2025-03-01T00:00:00Z","status":"public"},{"project":[{"call_identifier":"H2020","_id":"62796744-2b32-11ec-9570-940b20777f1d","name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331"}],"language":[{"iso":"eng"}],"ec_funded":1,"author":[{"id":"1949f904-edfb-11eb-afb5-e2dfddabb93b","last_name":"Riabov","first_name":"Volodymyr","full_name":"Riabov, Volodymyr"}],"OA_type":"green","month":"02","intvolume":"        61","publication_status":"published","article_type":"original","doi":"10.1214/23-AIHP1438","publication_identifier":{"issn":["0246-0203"]},"oa":1,"corr_author":"1","fulldoi":"https://doi.org/10.1214/23-AIHP1438","arxiv":1,"article_processing_charge":"No","publisher":"Institute of Mathematical Statistics","publication":"Annales de l'institut Henri Poincare (B) Probability and Statistics","date_updated":"2025-05-19T13:54:31Z","OA_place":"repository","quality_controlled":"1","oa_version":"Preprint","volume":61,"external_id":{"isi":["001427953600004"],"arxiv":["2301.01712"]},"page":"129-154","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2301.01712"}],"year":"2025","abstract":[{"text":"We prove a universal mesoscopic central limit theorem for linear eigenvalue statistics of a Wigner-type matrix inside the bulk of the spectrum with compactly supported twice continuously differentiable test functions. The main novel ingredient is an optimal local law for the two-point function $T(z,\\zeta)$  and a general class of related quantities involving two resolvents at nearby spectral parameters.","lang":"eng"},{"lang":"fre","text":"On établit un théorème limite central universel pour les statistiques linéaires mésoscopiques des valeurs propres d’une matrice de type Wigner au milieu du spectre, avec des fonctions de classe \r\n et à support compact. La principale nouveauté de cette approche est qu’elle repose sur une loi locale optimale pour la fonction à deux points $T(z,\\zeta)$ , ainsi que pour une classe plus générale d’observables impliquant deux résolvantes évaluées en des paramètres proches."}],"_id":"15128","acknowledgement":"I would like to express my gratitude to László Erdős for suggesting the project and supervising my work. I am also thankful to Yuanyuan Xu and Oleksii Kolupaiev for many helpful discussions. Furthermore, I am grateful to Guillaume Dubach for translating the abstract into French.\r\nThe author was supported by the ERC Advanced Grant “RMTBeyond” No. 101020331.","department":[{"_id":"GradSch"},{"_id":"LaEr"}],"date_published":"2025-02-01T00:00:00Z","status":"public","title":"Mesoscopic eigenvalue statistics for Wigner-type matrices","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","isi":1,"issue":"1","citation":{"mla":"Riabov, Volodymyr. “Mesoscopic Eigenvalue Statistics for Wigner-Type Matrices.” <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>, vol. 61, no. 1, Institute of Mathematical Statistics, 2025, pp. 129–54, doi:<a href=\"https://doi.org/10.1214/23-AIHP1438\">10.1214/23-AIHP1438</a>.","apa":"Riabov, V. (2025). Mesoscopic eigenvalue statistics for Wigner-type matrices. <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/23-AIHP1438\">https://doi.org/10.1214/23-AIHP1438</a>","short":"V. Riabov, Annales de l’institut Henri Poincare (B) Probability and Statistics 61 (2025) 129–154.","ieee":"V. Riabov, “Mesoscopic eigenvalue statistics for Wigner-type matrices,” <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>, vol. 61, no. 1. Institute of Mathematical Statistics, pp. 129–154, 2025.","ista":"Riabov V. 2025. Mesoscopic eigenvalue statistics for Wigner-type matrices. Annales de l’institut Henri Poincare (B) Probability and Statistics. 61(1), 129–154.","ama":"Riabov V. Mesoscopic eigenvalue statistics for Wigner-type matrices. <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>. 2025;61(1):129-154. doi:<a href=\"https://doi.org/10.1214/23-AIHP1438\">10.1214/23-AIHP1438</a>","chicago":"Riabov, Volodymyr. “Mesoscopic Eigenvalue Statistics for Wigner-Type Matrices.” <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>. Institute of Mathematical Statistics, 2025. <a href=\"https://doi.org/10.1214/23-AIHP1438\">https://doi.org/10.1214/23-AIHP1438</a>."},"date_created":"2024-03-20T09:41:04Z","type":"journal_article"},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"related_material":{"record":[{"relation":"shorter_version","id":"11355","status":"public"}]},"publication":"Formal Methods in System Design","publisher":"Springer Nature","date_updated":"2025-12-30T06:50:51Z","quality_controlled":"1","OA_place":"publisher","oa_version":"Published Version","page":"3-48","external_id":{"isi":["001230084200001"],"arxiv":["2002.06465"]},"volume":66,"file":[{"success":1,"file_id":"20879","checksum":"244a71a916103b8ea08e9d0bab32bcd9","file_size":3860690,"date_updated":"2025-12-30T06:50:12Z","date_created":"2025-12-30T06:50:12Z","file_name":"2025_FormalMethodsSysDesign_Bartocci.pdf","relation":"main_file","creator":"dernst","content_type":"application/pdf","access_level":"open_access"}],"year":"2025","author":[{"full_name":"Bartocci, Ezio","last_name":"Bartocci","first_name":"Ezio"},{"id":"40960E6E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5199-3143","first_name":"Thomas","last_name":"Ferrere","full_name":"Ferrere, Thomas"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger","first_name":"Thomas A","orcid":"0000-0002-2985-7724","full_name":"Henzinger, Thomas A"},{"id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87","last_name":"Nickovic","first_name":"Dejan","full_name":"Nickovic, Dejan"},{"orcid":"0000-0002-8741-5799","first_name":"Ana","last_name":"Oliveira da Costa","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4","full_name":"Oliveira da Costa, Ana"}],"project":[{"name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"},{"_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502","name":"Interface Theory for Security and Privacy"}],"language":[{"iso":"eng"}],"ec_funded":1,"OA_type":"hybrid","month":"05","article_type":"original","intvolume":"        66","ddc":["000"],"publication_status":"published","doi":"10.1007/s10703-024-00447-0","fulldoi":"https://doi.org/10.1007/s10703-024-00447-0","corr_author":"1","arxiv":1,"article_processing_charge":"Yes (via OA deal)","PlanS_conform":"1","oa":1,"publication_identifier":{"issn":["0925-9856"],"eissn":["1572-8102"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Information-flow interfaces","day":"01","scopus_import":"1","isi":1,"date_created":"2024-06-02T22:00:57Z","citation":{"mla":"Bartocci, Ezio, et al. “Information-Flow Interfaces.” <i>Formal Methods in System Design</i>, vol. 66, Springer Nature, 2025, pp. 3–48, doi:<a href=\"https://doi.org/10.1007/s10703-024-00447-0\">10.1007/s10703-024-00447-0</a>.","ieee":"E. Bartocci, T. Ferrere, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Information-flow interfaces,” <i>Formal Methods in System Design</i>, vol. 66. Springer Nature, pp. 3–48, 2025.","apa":"Bartocci, E., Ferrere, T., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A. (2025). Information-flow interfaces. <i>Formal Methods in System Design</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10703-024-00447-0\">https://doi.org/10.1007/s10703-024-00447-0</a>","short":"E. Bartocci, T. Ferrere, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Formal Methods in System Design 66 (2025) 3–48.","ista":"Bartocci E, Ferrere T, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Information-flow interfaces. Formal Methods in System Design. 66, 3–48.","chicago":"Bartocci, Ezio, Thomas Ferrere, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Information-Flow Interfaces.” <i>Formal Methods in System Design</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10703-024-00447-0\">https://doi.org/10.1007/s10703-024-00447-0</a>.","ama":"Bartocci E, Ferrere T, Henzinger TA, Nickovic D, Oliveira da Costa A. Information-flow interfaces. <i>Formal Methods in System Design</i>. 2025;66:3-48. doi:<a href=\"https://doi.org/10.1007/s10703-024-00447-0\">10.1007/s10703-024-00447-0</a>"},"type":"journal_article","_id":"17094","abstract":[{"lang":"eng","text":"Contract-based design is a promising methodology for taming the complexity of developing sophisticated systems. A formal contract distinguishes between assumptions, which are constraints that the designer of a component puts on the environments in which the component can be used safely, and guarantees, which are promises that the designer asks from the team that implements the component. A theory of formal contracts can be formalized as an interface theory, which supports the composition and refinement of both assumptions and guarantees. Although there is a rich landscape of contract-based design methods that address functional and extra-functional properties, we present the first interface theory designed to ensure system-wide security properties. Our framework provides a refinement relation and a composition operation that support both incremental design and independent implementability. We develop our theory for both stateless and stateful interfaces. Additionally, we introduce information-flow contracts where assumptions and guarantees are sets of flow relations. We use these contracts to illustrate how to enrich information-flow interfaces with a semantic view. We illustrate the applicability of our framework with two examples inspired by the automotive domain."}],"acknowledgement":"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 956123 and it was funded in part by the Austrian Science Fund (FWF) project W1255-N23, by the Austrian FWF project ZK-35, by the FWF project SpyCoDe 10.55776/F85 and by the ERC-2020-AdG 101020093. This paper extends the text and the results of the manuscript published at FASE 2022 [1].","file_date_updated":"2025-12-30T06:50:12Z","has_accepted_license":"1","date_published":"2025-05-01T00:00:00Z","department":[{"_id":"ToHe"}],"status":"public"},{"status":"public","date_published":"2025-01-15T00:00:00Z","department":[{"_id":"MaKw"}],"acknowledgement":"This work was initiated at the annual workshop of the Combinatorics and Graph Theory group of Freie Universität Berlin in Wilhelmsaue in September 2023. The authors would like to thank the institution for enabling this research. Finally, the fourth author would like to thank Tibor Szabó and the Combinatorics and Graph Theory group at Freie Universität Berlin for their hospitality during the research visit. Additionally, we thank Moharram Iradmusa for bringing the papers [5], [7] to our attention. Finally, we thank the anonymous referees for their suggestions on the manuscript, which have improved the quality of the document.\r\nM.A.: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413 .\r\nS.B.: The research leading to these results was supported by EPSRC, UK, grant no. EP/V048287/1. There are no additional data beyond that contained within the main manuscript.\r\nS.R.: Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – The Berlin Mathematics Research Center MATH+ (EXC-2046/1, project ID: 390685689).\r\nJ.R. acknowledges the support of the Grant PID2020-113082GB-I00 funded by MICIU/AEI/10.13039/501100011033, Spain, and the Severo Ochoa and María de Maeztu Program for Centers and Units of Excellence in R&D, Spain (CEX2020-001084-M).","has_accepted_license":"1","file_date_updated":"2025-01-13T09:25:59Z","_id":"18478","abstract":[{"lang":"eng","text":"For a given graph G=(V,E), we define its \\emph{nth subdivision} as the graph obtained from G by replacing every edge by a path of length n. We also define the \\emph{mth power} of G as the graph on vertex set V where we connect every pair of vertices at distance at most m in G. In this paper, we study the chromatic number of powers of subdivisions of graphs and resolve the case m=n asymptotically. In particular, our result confirms a conjecture of Mozafari-Nia and Iradmusa in the case m=n=3 in a strong sense."}],"type":"journal_article","citation":{"ista":"Anastos M, Boyadzhiyska S, Rathke S, Rué J. 2025. On the chromatic number of powers of subdivisions of graphs. Discrete Applied Mathematics. 360, 506–511.","chicago":"Anastos, Michael, Simona Boyadzhiyska, Silas Rathke, and Juanjo Rué. “On the Chromatic Number of Powers of Subdivisions of Graphs.” <i>Discrete Applied Mathematics</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.dam.2024.10.002\">https://doi.org/10.1016/j.dam.2024.10.002</a>.","ama":"Anastos M, Boyadzhiyska S, Rathke S, Rué J. On the chromatic number of powers of subdivisions of graphs. <i>Discrete Applied Mathematics</i>. 2025;360:506-511. doi:<a href=\"https://doi.org/10.1016/j.dam.2024.10.002\">10.1016/j.dam.2024.10.002</a>","short":"M. Anastos, S. Boyadzhiyska, S. Rathke, J. Rué, Discrete Applied Mathematics 360 (2025) 506–511.","ieee":"M. Anastos, S. Boyadzhiyska, S. Rathke, and J. Rué, “On the chromatic number of powers of subdivisions of graphs,” <i>Discrete Applied Mathematics</i>, vol. 360. Elsevier, pp. 506–511, 2025.","apa":"Anastos, M., Boyadzhiyska, S., Rathke, S., &#38; Rué, J. (2025). On the chromatic number of powers of subdivisions of graphs. <i>Discrete Applied Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.dam.2024.10.002\">https://doi.org/10.1016/j.dam.2024.10.002</a>","mla":"Anastos, Michael, et al. “On the Chromatic Number of Powers of Subdivisions of Graphs.” <i>Discrete Applied Mathematics</i>, vol. 360, Elsevier, 2025, pp. 506–11, doi:<a href=\"https://doi.org/10.1016/j.dam.2024.10.002\">10.1016/j.dam.2024.10.002</a>."},"date_created":"2024-10-27T23:01:44Z","scopus_import":"1","isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"On the chromatic number of powers of subdivisions of graphs","day":"15","fulldoi":"https://doi.org/10.1016/j.dam.2024.10.002","corr_author":"1","article_processing_charge":"Yes (in subscription journal)","arxiv":1,"publication_identifier":{"issn":["0166-218X"]},"oa":1,"doi":"10.1016/j.dam.2024.10.002","OA_type":"hybrid","article_type":"original","ddc":["510"],"intvolume":"       360","month":"01","publication_status":"published","author":[{"full_name":"Anastos, Michael","id":"0b2a4358-bb35-11ec-b7b9-e3279b593dbb","last_name":"Anastos","first_name":"Michael"},{"full_name":"Boyadzhiyska, Simona","last_name":"Boyadzhiyska","first_name":"Simona"},{"last_name":"Rathke","first_name":"Silas","full_name":"Rathke, Silas"},{"last_name":"Rué","first_name":"Juanjo","full_name":"Rué, Juanjo"}],"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"language":[{"iso":"eng"}],"ec_funded":1,"year":"2025","external_id":{"arxiv":["2404.05542"],"isi":["001343647000001"]},"page":"506-511","file":[{"date_created":"2025-01-13T09:25:59Z","file_name":"2025_DiscreteApplMath_Anastos.pdf","access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","checksum":"bd20a13e56b3ea01daf5e7aca5247c60","file_id":"18836","success":1,"file_size":441060,"date_updated":"2025-01-13T09:25:59Z"}],"volume":360,"quality_controlled":"1","date_updated":"2025-04-14T07:54:56Z","OA_place":"publisher","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"Discrete Applied Mathematics","publisher":"Elsevier"},{"_id":"18529","abstract":[{"text":"Temporal networks are obtained from time-dependent interactions among individuals, whereas the interactions can be emails, phone calls, face-to-face meetings, or work collaboration. In this article, a temporal game framework is established, in which interactions among rational individuals are embedded into two-player games in a time-dependent manner. This allows studying the time-dependent complexity and variability of interactions, and the way they affect prosocial behaviors. Based on this simple mathematical model, it is found that the level of cooperation is promoted when the time of collaboration is equally limited for every individual. This observation is confirmed by a series of systematic human experiments on over 1,400 subjects, forming a foundation for comprehensively describing human temporal interactions in collaboration. The research results reveal an important incentive for human cooperation, leading to a better understanding of a fascinating aspect of human nature in society.","lang":"eng"}],"status":"public","department":[{"_id":"KrCh"}],"date_published":"2025-01-01T00:00:00Z","isi":1,"scopus_import":"1","issue":"1","day":"01","title":"Limitation of time promotes cooperation in structured collaboration systems","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","date_created":"2024-11-10T23:02:00Z","citation":{"short":"Y. Zhang, J. Wang, G. Wen, J. Guan, S. Zhou, G. Chen, K. Chatterjee, M. Perc, IEEE Transactions on Network Science and Engineering 12 (2025) 4–12.","apa":"Zhang, Y., Wang, J., Wen, G., Guan, J., Zhou, S., Chen, G., … Perc, M. (2025). Limitation of time promotes cooperation in structured collaboration systems. <i>IEEE Transactions on Network Science and Engineering</i>. IEEE. <a href=\"https://doi.org/10.1109/TNSE.2024.3481434\">https://doi.org/10.1109/TNSE.2024.3481434</a>","ieee":"Y. Zhang <i>et al.</i>, “Limitation of time promotes cooperation in structured collaboration systems,” <i>IEEE Transactions on Network Science and Engineering</i>, vol. 12, no. 1. IEEE, pp. 4–12, 2025.","mla":"Zhang, Yichao, et al. “Limitation of Time Promotes Cooperation in Structured Collaboration Systems.” <i>IEEE Transactions on Network Science and Engineering</i>, vol. 12, no. 1, IEEE, 2025, pp. 4–12, doi:<a href=\"https://doi.org/10.1109/TNSE.2024.3481434\">10.1109/TNSE.2024.3481434</a>.","chicago":"Zhang, Yichao, Jiasheng Wang, Guanghui Wen, Jihong Guan, Shuigeng Zhou, Guanrong Chen, Krishnendu Chatterjee, and Matjaz Perc. “Limitation of Time Promotes Cooperation in Structured Collaboration Systems.” <i>IEEE Transactions on Network Science and Engineering</i>. IEEE, 2025. <a href=\"https://doi.org/10.1109/TNSE.2024.3481434\">https://doi.org/10.1109/TNSE.2024.3481434</a>.","ama":"Zhang Y, Wang J, Wen G, et al. Limitation of time promotes cooperation in structured collaboration systems. <i>IEEE Transactions on Network Science and Engineering</i>. 2025;12(1):4-12. doi:<a href=\"https://doi.org/10.1109/TNSE.2024.3481434\">10.1109/TNSE.2024.3481434</a>","ista":"Zhang Y, Wang J, Wen G, Guan J, Zhou S, Chen G, Chatterjee K, Perc M. 2025. Limitation of time promotes cooperation in structured collaboration systems. IEEE Transactions on Network Science and Engineering. 12(1), 4–12."},"intvolume":"        12","month":"01","publication_status":"published","article_type":"original","OA_type":"closed access","language":[{"iso":"eng"}],"author":[{"full_name":"Zhang, Yichao","last_name":"Zhang","first_name":"Yichao"},{"full_name":"Wang, Jiasheng","last_name":"Wang","first_name":"Jiasheng"},{"last_name":"Wen","first_name":"Guanghui","full_name":"Wen, Guanghui"},{"last_name":"Guan","first_name":"Jihong","full_name":"Guan, Jihong"},{"first_name":"Shuigeng","last_name":"Zhou","full_name":"Zhou, Shuigeng"},{"full_name":"Chen, Guanrong","last_name":"Chen","first_name":"Guanrong"},{"full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","last_name":"Chatterjee","first_name":"Krishnendu"},{"first_name":"Matjaz","last_name":"Perc","full_name":"Perc, Matjaz"}],"publication_identifier":{"eissn":["2327-4697"]},"article_processing_charge":"No","fulldoi":"https://doi.org/10.1109/TNSE.2024.3481434","doi":"10.1109/TNSE.2024.3481434","oa_version":"None","date_updated":"2025-02-27T12:35:48Z","quality_controlled":"1","publication":"IEEE Transactions on Network Science and Engineering","publisher":"IEEE","year":"2025","volume":12,"external_id":{"isi":["001385382200040"]},"page":"4-12"},{"doi":"10.1007/s10971-024-06607-2","publication_identifier":{"eissn":["1573-4846"],"issn":["0928-0707"]},"fulldoi":"https://doi.org/10.1007/s10971-024-06607-2","article_processing_charge":"No","language":[{"iso":"eng"}],"author":[{"first_name":"Madhu","last_name":"Verma","full_name":"Verma, Madhu"},{"last_name":"Kumar","first_name":"Ajay","full_name":"Kumar, Ajay"},{"first_name":"Vijay Kumar","last_name":"Thakur","full_name":"Thakur, Vijay Kumar"},{"first_name":"Akanksha","last_name":"Maurya","full_name":"Maurya, Akanksha"},{"full_name":"Kumar, Sachin","last_name":"Kumar","first_name":"Sachin"},{"id":"12d625da-9cb3-11ed-9667-af09d37d3f0a","last_name":"Singh","first_name":"Saurabh","orcid":"0000-0003-2209-5269","full_name":"Singh, Saurabh"},{"last_name":"Srivastav","first_name":"Simant Kumar","full_name":"Srivastav, Simant Kumar"}],"OA_type":"closed access","article_type":"original","intvolume":"       113","publication_status":"published","month":"02","page":"356-373","external_id":{"isi":["001348590700001"]},"volume":113,"year":"2025","publication":"Journal of Sol-Gel Science and Technology","publisher":"Springer Nature","date_updated":"2025-05-19T14:00:43Z","quality_controlled":"1","oa_version":"None","department":[{"_id":"MaIb"}],"date_published":"2025-02-01T00:00:00Z","status":"public","_id":"18558","abstract":[{"text":"The current investigation presents a facile and cost-effective sol-gel approach for the synthesis of phase-pure multiferroic bismuth ferrite (BiFeO3) nanoparticles (BFO NPs) by using propylene glycol as a complexing agent, intended for use as a photocatalyst to efficiently degrade organic dyes in aqueous solutions under natural sunlight. Characterization techniques, including thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD), elucidated a plausible reaction pathway for the formation of phase-pure BFO NPs. Rietveld refinement of the XRD data, in conjunction with transmission electron microscopy (TEM) and Raman spectroscopy, confirmed the synthesis of single-phase BFO NPs at 400 °C, displaying a space group of R3c and an average crystallite size of 25 nm. UV–visible diffuse reflectance spectroscopy revealed an absorption cut-off wavelength near 590 nm, corresponding to a band gap of 2.08 eV, indicating the capability of BFO NPs to absorb visible light within the 400–590 nm range. BFO NPs have shown efficient and rapid photocatalytic degradation of methylene blue (MB) in acidic, neutral, and basic pH conditions under natural sunlight. This is attributed to the intrinsic ferroelectric and ferromagnetic ordering present in synthesized BFO NPs which facilitates the separation and migration of photoinduced charges through band bending phenomena at the interface.","lang":"eng"}],"acknowledgement":"Simant Kumar Srivastav greatly acknowledges the University Grant Commission (UGC), New Delhi, India for providing BSR start-up grant to carry out this research work.\r\nThis research was supported by start-up grant of the University Grant Commission (UGC), New Delhi, India through project no F-30-500/2019 (BSR).","date_created":"2024-11-17T23:01:47Z","citation":{"ieee":"M. Verma <i>et al.</i>, “Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles,” <i>Journal of Sol-Gel Science and Technology</i>, vol. 113. Springer Nature, pp. 356–373, 2025.","apa":"Verma, M., Kumar, A., Thakur, V. K., Maurya, A., Kumar, S., Singh, S., &#38; Srivastav, S. K. (2025). Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles. <i>Journal of Sol-Gel Science and Technology</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10971-024-06607-2\">https://doi.org/10.1007/s10971-024-06607-2</a>","short":"M. Verma, A. Kumar, V.K. Thakur, A. Maurya, S. Kumar, S. Singh, S.K. Srivastav, Journal of Sol-Gel Science and Technology 113 (2025) 356–373.","mla":"Verma, Madhu, et al. “Efficient and Rapid Sunlight-Driven Photocatalytic Degradation of Methylene Blue Dye Using Multiferroic BiFeO3 Nanoparticles.” <i>Journal of Sol-Gel Science and Technology</i>, vol. 113, Springer Nature, 2025, pp. 356–73, doi:<a href=\"https://doi.org/10.1007/s10971-024-06607-2\">10.1007/s10971-024-06607-2</a>.","ista":"Verma M, Kumar A, Thakur VK, Maurya A, Kumar S, Singh S, Srivastav SK. 2025. Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles. Journal of Sol-Gel Science and Technology. 113, 356–373.","chicago":"Verma, Madhu, Ajay Kumar, Vijay Kumar Thakur, Akanksha Maurya, Sachin Kumar, Saurabh Singh, and Simant Kumar Srivastav. “Efficient and Rapid Sunlight-Driven Photocatalytic Degradation of Methylene Blue Dye Using Multiferroic BiFeO3 Nanoparticles.” <i>Journal of Sol-Gel Science and Technology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10971-024-06607-2\">https://doi.org/10.1007/s10971-024-06607-2</a>.","ama":"Verma M, Kumar A, Thakur VK, et al. Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles. <i>Journal of Sol-Gel Science and Technology</i>. 2025;113:356-373. doi:<a href=\"https://doi.org/10.1007/s10971-024-06607-2\">10.1007/s10971-024-06607-2</a>"},"type":"journal_article","title":"Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","isi":1},{"file_date_updated":"2024-11-28T06:52:38Z","has_accepted_license":"1","acknowledgement":"M.L. acknowledge support by the Dioscuri program initiated by the Max Planck Society, jointly managed with the National Science Centre (Poland), and mutually funded by the Polish Ministry of Science and Higher Education and the German Federal Ministry of Education and Research. M.L. also acknowledges that this project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413. Research of M.M. is partially supported by the Polish National Science Center under Opus Grant No. 2019/35/B/ST1/00874. The work of K.M. was partially supported by the National Science Foundation under awards DMS-1839294 and HDR TRIPODS award CCF-1934924, DARPA contract HR0011-16-2-0033, National Institutes of Health award R01 GM126555, Air Force Office of Scientific Research under award numbers FA9550-23-1-0011, AWD00010853-MOD002 and MURI FA9550-23-1-0400. K.M. was also supported by a grant from the Simons Foundation. Open access funding provided by Institute of Science and Technology (IST Austria). ","_id":"18580","abstract":[{"text":"Motivated by the study of recurrent orbits and dynamics within a Morse set of a Morse decomposition we introduce the concept of Morse predecomposition of an isolated invariant set within the setting of both combinatorial and classical dynamical systems. While Morse decomposition summarizes solely the gradient part of a dynamical system, the developed generalization extends to the recurrent component as well. In particular, a chain recurrent set, which is indecomposable in terms of Morse decomposition, can be represented more finely in the Morse predecomposition framework. This generalization is achieved by forgoing the poset structure inherent to Morse decomposition and relaxing the notion of connection between Morse sets (elements of Morse decomposition) in favor of what we term ’links’. We prove that a Morse decomposition is a special case of Morse predecomposition indexed by a poset. Additionally, we show how a Morse predecomposition may be condensed back to retrieve a Morse decomposition.","lang":"eng"}],"status":"public","article_number":"5","department":[{"_id":"UlWa"}],"date_published":"2025-02-01T00:00:00Z","scopus_import":"1","isi":1,"issue":"1","title":"Morse predecomposition of an invariant set","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","date_created":"2024-11-24T23:01:47Z","citation":{"mla":"Lipiński, Michał, et al. “Morse Predecomposition of an Invariant Set.” <i>Qualitative Theory of Dynamical Systems</i>, vol. 24, no. 1, 5, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s12346-024-01144-3\">10.1007/s12346-024-01144-3</a>.","ieee":"M. Lipiński, K. Mischaikow, and M. Mrozek, “Morse predecomposition of an invariant set,” <i>Qualitative Theory of Dynamical Systems</i>, vol. 24, no. 1. Springer Nature, 2025.","apa":"Lipiński, M., Mischaikow, K., &#38; Mrozek, M. (2025). Morse predecomposition of an invariant set. <i>Qualitative Theory of Dynamical Systems</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s12346-024-01144-3\">https://doi.org/10.1007/s12346-024-01144-3</a>","short":"M. Lipiński, K. Mischaikow, M. Mrozek, Qualitative Theory of Dynamical Systems 24 (2025).","ama":"Lipiński M, Mischaikow K, Mrozek M. Morse predecomposition of an invariant set. <i>Qualitative Theory of Dynamical Systems</i>. 2025;24(1). doi:<a href=\"https://doi.org/10.1007/s12346-024-01144-3\">10.1007/s12346-024-01144-3</a>","chicago":"Lipiński, Michał, Konstantin Mischaikow, and Marian Mrozek. “Morse Predecomposition of an Invariant Set.” <i>Qualitative Theory of Dynamical Systems</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s12346-024-01144-3\">https://doi.org/10.1007/s12346-024-01144-3</a>.","ista":"Lipiński M, Mischaikow K, Mrozek M. 2025. Morse predecomposition of an invariant set. Qualitative Theory of Dynamical Systems. 24(1), 5."},"OA_type":"hybrid","intvolume":"        24","month":"02","ddc":["514","510"],"publication_status":"published","article_type":"original","project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"language":[{"iso":"eng"}],"ec_funded":1,"author":[{"id":"dfffb474-4317-11ee-8f5c-fe3fc95a425e","orcid":"0000-0001-9789-9750","last_name":"Lipiński","first_name":"Michał","full_name":"Lipiński, Michał"},{"first_name":"Konstantin","last_name":"Mischaikow","full_name":"Mischaikow, Konstantin"},{"last_name":"Mrozek","first_name":"Marian","full_name":"Mrozek, Marian"}],"oa":1,"publication_identifier":{"issn":["1575-5460"],"eissn":["1662-3592"]},"corr_author":"1","fulldoi":"https://doi.org/10.1007/s12346-024-01144-3","arxiv":1,"article_processing_charge":"Yes (via OA deal)","doi":"10.1007/s12346-024-01144-3","quality_controlled":"1","OA_place":"publisher","date_updated":"2025-04-14T07:54:56Z","oa_version":"Published Version","publisher":"Springer Nature","publication":"Qualitative Theory of Dynamical Systems","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"year":"2025","file":[{"access_level":"open_access","content_type":"application/pdf","creator":"mlipinsk","relation":"main_file","file_name":"2025_predecomposition.pdf","date_created":"2024-11-28T06:52:38Z","date_updated":"2024-11-28T06:52:38Z","file_size":1483668,"file_id":"18595","checksum":"73309a57cc798d696caa57b6aa1467d8","success":1}],"volume":24,"external_id":{"arxiv":["2312.08013"],"isi":["001356000500005"]}},{"department":[{"_id":"JiFr"}],"date_published":"2025-01-13T00:00:00Z","status":"public","article_number":"101181","_id":"18619","abstract":[{"text":"Brassinosteroids (BRs) are steroidal phytohormones indispensable for plant growth, development, and responses to environmental stresses. The export of bioactive BRs to the apoplast is essential for BR signalling initiation, which requires binding of BR molecule to the extracellular domains of the plasma membrane-localized receptor complex. We have previously shown that the Arabidopsis thaliana ATP-binding cassette (ABC) transporter, ABCB19, functions as a BR exporter, and together with its close homologue, ABCB1, positively regulate BR signalling. Here, we demonstrate that ABCB1 is another BR transporter. The ATP hydrolysis activity of ABCB1 was stimulated by bioactive BRs, and its transport activity was confirmed in proteoliposomes and protoplasts. Structures of ABCB1 in substrate-unbound (apo), brassinolide (BL)-bound, and ATP plus BL-bound states were determined. In the BL-bound structure, BL was bound to the hydrophobic cavity formed by the transmembrane domain, and triggered local conformational changes. Together, our data provide additional insights into the ABC transporter-mediated BR export.","lang":"eng"}],"has_accepted_license":"1","DOAJ_listed":"1","file_date_updated":"2025-04-16T09:02:05Z","acknowledgement":"We thank the Cryo-EM Center of the University of Science and Technology of China for the EM facility support. We thank Yaowei Wang, Yongming Luo, and Nemanja Vukašinović (VIB-UGhent, Belgium) for useful discussions and technical support. L.S. is supported by an Outstanding Young Scholar Award from the Qiu Shi Science and Technologies Foundation and a Young Scholar Award from the Cyrus Tang Foundation. No conflict of interest is declared.","citation":{"short":"H. Wei, H. Zhu, W. Ying, H. Janssens, M. Kvasnica, J. Winne, Y. Gao, J. Friml, Q. Ma, S. Tan, X. Liu, E. Russinova, L. Sun, Plant Communications 6 (2025).","ieee":"H. Wei <i>et al.</i>, “Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1,” <i>Plant Communications</i>, vol. 6, no. 1. Elsevier, 2025.","apa":"Wei, H., Zhu, H., Ying, W., Janssens, H., Kvasnica, M., Winne, J., … Sun, L. (2025). Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. <i>Plant Communications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xplc.2024.101181\">https://doi.org/10.1016/j.xplc.2024.101181</a>","mla":"Wei, H., et al. “Structural Insights into Brassinosteroid Export Mediated by the Arabidopsis ABC Transporter ABCB1.” <i>Plant Communications</i>, vol. 6, no. 1, 101181, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.xplc.2024.101181\">10.1016/j.xplc.2024.101181</a>.","ama":"Wei H, Zhu H, Ying W, et al. Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. <i>Plant Communications</i>. 2025;6(1). doi:<a href=\"https://doi.org/10.1016/j.xplc.2024.101181\">10.1016/j.xplc.2024.101181</a>","chicago":"Wei, H, H Zhu, W Ying, H Janssens, M Kvasnica, JM Winne, Y Gao, et al. “Structural Insights into Brassinosteroid Export Mediated by the Arabidopsis ABC Transporter ABCB1.” <i>Plant Communications</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.xplc.2024.101181\">https://doi.org/10.1016/j.xplc.2024.101181</a>.","ista":"Wei H, Zhu H, Ying W, Janssens H, Kvasnica M, Winne J, Gao Y, Friml J, Ma Q, Tan S, Liu X, Russinova E, Sun L. 2025. Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. Plant Communications. 6(1), 101181."},"date_created":"2024-12-04T11:21:16Z","type":"journal_article","title":"Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1","day":"13","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","isi":1,"issue":"1","doi":"10.1016/j.xplc.2024.101181","pmid":1,"oa":1,"publication_identifier":{"issn":["2590-3462"]},"fulldoi":"https://doi.org/10.1016/j.xplc.2024.101181","article_processing_charge":"Yes","language":[{"iso":"eng"}],"author":[{"full_name":"Wei, H","last_name":"Wei","first_name":"H"},{"full_name":"Zhu, H","first_name":"H","last_name":"Zhu"},{"first_name":"W","last_name":"Ying","full_name":"Ying, W"},{"full_name":"Janssens, H","last_name":"Janssens","first_name":"H"},{"first_name":"M","last_name":"Kvasnica","full_name":"Kvasnica, M"},{"full_name":"Winne, JM","first_name":"JM","last_name":"Winne"},{"full_name":"Gao, Y","last_name":"Gao","first_name":"Y"},{"full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","first_name":"Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Q","last_name":"Ma","full_name":"Ma, Q"},{"last_name":"Tan","first_name":"S","full_name":"Tan, S"},{"full_name":"Liu, X","last_name":"Liu","first_name":"X"},{"last_name":"Russinova","first_name":"E","full_name":"Russinova, E"},{"first_name":"L","last_name":"Sun","full_name":"Sun, L"}],"OA_type":"gold","publication_status":"published","month":"01","ddc":["580"],"intvolume":"         6","article_type":"original","volume":6,"external_id":{"isi":["001416757300001"],"pmid":["39497419"]},"file":[{"file_size":4443183,"success":1,"checksum":"7b0e4511e43cc0da06730c3edb7c1167","file_id":"19575","date_updated":"2025-04-16T09:02:05Z","date_created":"2025-04-16T09:02:05Z","relation":"main_file","content_type":"application/pdf","creator":"dernst","access_level":"open_access","file_name":"2025_PlantComm_Wei.pdf"}],"year":"2025","publication":"Plant Communications","publisher":"Elsevier","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"date_updated":"2025-05-19T14:02:01Z","quality_controlled":"1","OA_place":"publisher","oa_version":"Published Version"},{"year":"2025","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2310.18238","open_access":"1"}],"external_id":{"isi":["001370682500001"],"arxiv":["2310.18238"]},"volume":461,"oa_version":"Preprint","OA_place":"repository","date_updated":"2025-04-15T07:16:53Z","quality_controlled":"1","publication":"Advances in Mathematics","publisher":"Elsevier","arxiv":1,"article_processing_charge":"No","corr_author":"1","fulldoi":"https://doi.org/10.1016/j.aim.2024.110055","oa":1,"publication_identifier":{"eissn":["1090-2082"],"issn":["0001-8708"]},"doi":"10.1016/j.aim.2024.110055","intvolume":"       461","article_type":"original","month":"02","publication_status":"published","OA_type":"green","author":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9823-6833","first_name":"Herbert","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert"},{"first_name":"Alexey","last_name":"Garber","full_name":"Garber, Alexey"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","last_name":"Saghafian","first_name":"Morteza","full_name":"Saghafian, Morteza"}],"language":[{"iso":"eng"}],"ec_funded":1,"project":[{"call_identifier":"H2020","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","grant_number":"788183","name":"Alpha Shape Theory Extended"},{"call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425","name":"Mathematics, Computer Science","grant_number":"Z00342"},{"name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"type":"journal_article","citation":{"chicago":"Edelsbrunner, Herbert, Alexey Garber, and Morteza Saghafian. “Order-2 Delaunay Triangulations Optimize Angles.” <i>Advances in Mathematics</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.aim.2024.110055\">https://doi.org/10.1016/j.aim.2024.110055</a>.","ama":"Edelsbrunner H, Garber A, Saghafian M. Order-2 Delaunay triangulations optimize angles. <i>Advances in Mathematics</i>. 2025;461. doi:<a href=\"https://doi.org/10.1016/j.aim.2024.110055\">10.1016/j.aim.2024.110055</a>","ista":"Edelsbrunner H, Garber A, Saghafian M. 2025. Order-2 Delaunay triangulations optimize angles. Advances in Mathematics. 461, 110055.","mla":"Edelsbrunner, Herbert, et al. “Order-2 Delaunay Triangulations Optimize Angles.” <i>Advances in Mathematics</i>, vol. 461, 110055, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.aim.2024.110055\">10.1016/j.aim.2024.110055</a>.","ieee":"H. Edelsbrunner, A. Garber, and M. Saghafian, “Order-2 Delaunay triangulations optimize angles,” <i>Advances in Mathematics</i>, vol. 461. Elsevier, 2025.","short":"H. Edelsbrunner, A. Garber, M. Saghafian, Advances in Mathematics 461 (2025).","apa":"Edelsbrunner, H., Garber, A., &#38; Saghafian, M. (2025). Order-2 Delaunay triangulations optimize angles. <i>Advances in Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.aim.2024.110055\">https://doi.org/10.1016/j.aim.2024.110055</a>"},"date_created":"2024-12-08T23:01:54Z","isi":1,"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","title":"Order-2 Delaunay triangulations optimize angles","article_number":"110055","status":"public","date_published":"2025-02-01T00:00:00Z","department":[{"_id":"HeEd"}],"acknowledgement":"Work by the first and third authors is partially supported by the European Research Council (ERC), grant no. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), grant no. I 02979-N35. Work by the second author is partially supported by the Alexander von Humboldt Foundation.","abstract":[{"text":"The local angle property of the (order-1) Delaunay triangulations of a generic set in R2\r\n asserts that the sum of two angles opposite a common edge is less than π. This paper extends this property to higher order and uses it to generalize two classic properties from order-1 to order-2: (1) among the complete level-2 hypertriangulations of a generic point set in R2, the order-2 Delaunay triangulation lexicographically maximizes the sorted angle vector; (2) among the maximal level-2 hypertriangulations of a generic point set in R2, the order-2 Delaunay triangulation is the only one that has the local angle property. We also use our method of establishing (2) to give a new short proof of the angle vector optimality for the (order-1) Delaunay triangulation. For order-1, both properties have been instrumental in numerous applications of Delaunay triangulations, and we expect that their generalization will make order-2 Delaunay triangulations more attractive to applications as well.","lang":"eng"}],"_id":"18626"},{"OA_place":"publisher","quality_controlled":"1","date_updated":"2025-05-19T14:01:21Z","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","publication":"Nature Astronomy","year":"2025","page":"280-292","volume":9,"external_id":{"pmid":["39990236"],"isi":["001420347200001"]},"file":[{"date_created":"2025-04-16T08:53:59Z","file_name":"2025_NatureAstronomy_deGraaff.pdf","creator":"dernst","relation":"main_file","content_type":"application/pdf","access_level":"open_access","success":1,"file_id":"19574","checksum":"fb9109951dfe72f08c04c72cd7cfba69","file_size":2034513,"date_updated":"2025-04-16T08:53:59Z"}],"OA_type":"hybrid","article_type":"original","intvolume":"         9","month":"02","ddc":["520"],"publication_status":"published","author":[{"first_name":"Anna","last_name":"De Graaff","full_name":"De Graaff, Anna"},{"last_name":"Setton","first_name":"David J.","full_name":"Setton, David J."},{"first_name":"Gabriel","last_name":"Brammer","full_name":"Brammer, Gabriel"},{"last_name":"Cutler","first_name":"Sam","full_name":"Cutler, Sam"},{"last_name":"Suess","first_name":"Katherine A.","full_name":"Suess, Katherine A."},{"last_name":"Labbé","first_name":"Ivo","full_name":"Labbé, Ivo"},{"full_name":"Leja, Joel","last_name":"Leja","first_name":"Joel"},{"last_name":"Weibel","first_name":"Andrea","full_name":"Weibel, Andrea"},{"full_name":"Maseda, Michael V.","first_name":"Michael V.","last_name":"Maseda"},{"full_name":"Whitaker, Katherine E.","last_name":"Whitaker","first_name":"Katherine E."},{"last_name":"Bezanson","first_name":"Rachel","full_name":"Bezanson, Rachel"},{"full_name":"Boogaard, Leindert A.","first_name":"Leindert A.","last_name":"Boogaard"},{"last_name":"Cleri","first_name":"Nikko J.","full_name":"Cleri, Nikko J."},{"full_name":"De Lucia, Gabriella","first_name":"Gabriella","last_name":"De Lucia"},{"full_name":"Franx, Marijn","first_name":"Marijn","last_name":"Franx"},{"full_name":"Greene, Jenny E.","first_name":"Jenny E.","last_name":"Greene"},{"full_name":"Hirschmann, Michaela","first_name":"Michaela","last_name":"Hirschmann"},{"orcid":"0000-0003-2871-127X","first_name":"Jorryt J","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J"},{"last_name":"Mcconachie","first_name":"Ian","full_name":"Mcconachie, Ian"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"full_name":"Oesch, Pascal A.","first_name":"Pascal A.","last_name":"Oesch"},{"first_name":"Sedona H.","last_name":"Price","full_name":"Price, Sedona H."},{"full_name":"Rix, Hans Walter","last_name":"Rix","first_name":"Hans Walter"},{"full_name":"Valentino, Francesco","first_name":"Francesco","last_name":"Valentino"},{"full_name":"Wang, Bingjie","first_name":"Bingjie","last_name":"Wang"},{"first_name":"Christina C.","last_name":"Williams","full_name":"Williams, Christina C."}],"language":[{"iso":"eng"}],"fulldoi":"https://doi.org/10.1038/s41550-024-02424-3","article_processing_charge":"Yes (via OA deal)","pmid":1,"oa":1,"publication_identifier":{"eissn":["2397-3366"]},"doi":"10.1038/s41550-024-02424-3","scopus_import":"1","isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Efficient formation of a massive quiescent galaxy at redshift 4.9","day":"01","type":"journal_article","citation":{"short":"A. De Graaff, D.J. Setton, G. Brammer, S. Cutler, K.A. Suess, I. Labbé, J. Leja, A. Weibel, M.V. Maseda, K.E. Whitaker, R. Bezanson, L.A. Boogaard, N.J. Cleri, G. De Lucia, M. Franx, J.E. Greene, M. Hirschmann, J.J. Matthee, I. Mcconachie, R.P. Naidu, P.A. Oesch, S.H. Price, H.W. Rix, F. Valentino, B. Wang, C.C. Williams, Nature Astronomy 9 (2025) 280–292.","apa":"De Graaff, A., Setton, D. J., Brammer, G., Cutler, S., Suess, K. A., Labbé, I., … Williams, C. C. (2025). Efficient formation of a massive quiescent galaxy at redshift 4.9. <i>Nature Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41550-024-02424-3\">https://doi.org/10.1038/s41550-024-02424-3</a>","ieee":"A. De Graaff <i>et al.</i>, “Efficient formation of a massive quiescent galaxy at redshift 4.9,” <i>Nature Astronomy</i>, vol. 9. Springer Nature, pp. 280–292, 2025.","mla":"De Graaff, Anna, et al. “Efficient Formation of a Massive Quiescent Galaxy at Redshift 4.9.” <i>Nature Astronomy</i>, vol. 9, Springer Nature, 2025, pp. 280–92, doi:<a href=\"https://doi.org/10.1038/s41550-024-02424-3\">10.1038/s41550-024-02424-3</a>.","ama":"De Graaff A, Setton DJ, Brammer G, et al. Efficient formation of a massive quiescent galaxy at redshift 4.9. <i>Nature Astronomy</i>. 2025;9:280-292. doi:<a href=\"https://doi.org/10.1038/s41550-024-02424-3\">10.1038/s41550-024-02424-3</a>","chicago":"De Graaff, Anna, David J. Setton, Gabriel Brammer, Sam Cutler, Katherine A. Suess, Ivo Labbé, Joel Leja, et al. “Efficient Formation of a Massive Quiescent Galaxy at Redshift 4.9.” <i>Nature Astronomy</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41550-024-02424-3\">https://doi.org/10.1038/s41550-024-02424-3</a>.","ista":"De Graaff A, Setton DJ, Brammer G, Cutler S, Suess KA, Labbé I, Leja J, Weibel A, Maseda MV, Whitaker KE, Bezanson R, Boogaard LA, Cleri NJ, De Lucia G, Franx M, Greene JE, Hirschmann M, Matthee JJ, Mcconachie I, Naidu RP, Oesch PA, Price SH, Rix HW, Valentino F, Wang B, Williams CC. 2025. Efficient formation of a massive quiescent galaxy at redshift 4.9. Nature Astronomy. 9, 280–292."},"date_created":"2024-12-08T23:01:56Z","acknowledgement":"We thank V. Buat, D. Burgarella and J. Zavala for sharing their NOEMA data and constraints on the dust-obscured star formation of RUBIES-EGS-QG-1. This work is partially based on observations carried out under project number W20CK with the IRAM NOEMA Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain). We thank C. Lagos for providing measurements from the SHARK simulation. This research was supported by the International Space Science Institute (ISSI) in Bern, through ISSI International Team Project No. 562. M.V.M., J.L. and B.W. acknowledge funding support from NASA through JWST-GO-4233. The Cosmic Dawn Center is funded by the Danish National Research Foundation (Grant No. DNRF140 to G.B., P.A.O. and K.E.W.). This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (Contract No. MB22.00072) and the Swiss National Science Foundation (Project Grant No. 200020_207349 to P.A.O.). Support for this work was provided by the Brinson Foundation through a Brinson Prize Fellowship grant (D.J.S.). K.A.S. is a NHFP Hubble Fellow. Support for this work was provided by NASA through the NASA Hubble Fellowship Grant No. HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS 5-26555 (R.P.N.). This work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. The observations in this work are associated with programmes ERS-1345, GO-2234, DDT-2750 and GO-4233. We gratefully acknowledge the CEERS and DDT-2750 teams for developing their observing programme with a zero-exclusive-access period. Open access funding provided by Max Planck Society.","file_date_updated":"2025-04-16T08:53:59Z","has_accepted_license":"1","abstract":[{"lang":"eng","text":"Within the established framework of structure formation, galaxies start as systems of low stellar mass and gradually grow into far more massive galaxies. The existence of massive galaxies in the first billion years of the Universe, as suggested by recent observations, seems to challenge this model, as such galaxies would require highly efficient conversion of baryons into stars. An even greater challenge in this epoch is the existence of massive galaxies that have already ceased forming stars. However, robust detections of early massive quiescent galaxies have been challenging due to the coarse wavelength sampling of photometric surveys. Here we report the spectroscopic confirmation with the James Webb Space Telescope of the quiescent galaxy RUBIES-EGS-QG-1 at redshift z = 4.90, 1.2 billion years after the Big Bang. Deep stellar absorption features in the spectrum reveal that the stellar mass of the galaxy of 1011 M⊙ formed in a short 200 Myr burst of star formation, after which star formation activity dropped rapidly and persistently. According to current galaxy formation models, systems with such rapid stellar mass growth and early quenching are too rare to plausibly occur in the small area probed spectroscopically with JWST. Instead, the discovery of RUBIES-EGS-QG-1 implies that early massive quiescent galaxies can be quenched earlier or exhaust gas available for star formation more efficiently than assumed at present."}],"_id":"18631","status":"public","date_published":"2025-02-01T00:00:00Z","department":[{"_id":"JoMa"}]},{"doi":"10.1002/mana.202400169","oa":1,"publication_identifier":{"eissn":["1522-2616"],"issn":["0025-584X"]},"fulldoi":"https://doi.org/10.1002/mana.202400169","article_processing_charge":"Yes (via OA deal)","arxiv":1,"project":[{"name":"Optimal Transport and Stochastic Dynamics","grant_number":"716117","_id":"256E75B8-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504"},{"_id":"34dbf174-11ca-11ed-8bc3-afe9d43d4b9c","name":"Configuration Spaces over Non-Smooth Spaces","grant_number":"E208"}],"ec_funded":1,"language":[{"iso":"eng"}],"author":[{"first_name":"Lorenzo","last_name":"Dello Schiavo","orcid":"0000-0002-9881-6870","id":"ECEBF480-9E4F-11EA-B557-B0823DDC885E","full_name":"Dello Schiavo, Lorenzo"},{"first_name":"Ronan","last_name":"Herry","full_name":"Herry, Ronan"},{"full_name":"Kopfer, Eva","last_name":"Kopfer","first_name":"Eva"},{"first_name":"Karl Theodor","last_name":"Sturm","full_name":"Sturm, Karl Theodor"}],"OA_type":"hybrid","article_type":"original","publication_status":"published","intvolume":"       298","ddc":["510"],"month":"01","volume":298,"page":"244-281","external_id":{"arxiv":["2302.02963"],"isi":["001366948500001"]},"file":[{"access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","file_name":"2025_MathNachrichten_DelloSchiavo.pdf","date_created":"2025-01-13T10:34:42Z","date_updated":"2025-01-13T10:34:42Z","file_size":1734511,"checksum":"1dc50d156feb777c86d779fb1c9ac875","file_id":"18838","success":1}],"year":"2025","publisher":"Wiley","publication":"Mathematische Nachrichten","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_updated":"2025-04-14T07:27:49Z","OA_place":"publisher","quality_controlled":"1","oa_version":"Published Version","department":[{"_id":"JaMa"}],"date_published":"2025-01-01T00:00:00Z","status":"public","abstract":[{"text":"For an arbitrary dimension (Formula presented.), we study: the polyharmonic Gaussian field (Formula presented.) on the discrete torus (Formula presented.), that is the random field whose law on (Formula presented.) given by (Formula presented.) where (Formula presented.) is the Lebesgue measure and (Formula presented.) is the discrete Laplacian; the associated discrete Liouville quantum gravity (LQG) measure associated with it, that is, the random measure on (Formula presented.) (Formula presented.) where (Formula presented.) is a regularity parameter. As (Formula presented.), we prove convergence of the fields (Formula presented.) to the polyharmonic Gaussian field (Formula presented.) on the continuous torus (Formula presented.), as well as convergence of the random measures (Formula presented.) to the LQG measure (Formula presented.) on (Formula presented.), for all (Formula presented.). ","lang":"eng"}],"_id":"18632","file_date_updated":"2025-01-13T10:34:42Z","has_accepted_license":"1","acknowledgement":"KTS is grateful to Christoph Thiele for valuable discussions and helpful references. LDS is grateful to Nathanaël Berestycki for valuable discussions on Gaussian Multiplicative Chaoses. The authors are grateful to an anonymous reviewer for suggestions which improved the presentation.\r\nThe authors gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the project ‘Random Riemannian Geometry’ within the SPP 2265 ‘Random Geometric Systems.'\r\nLDS gratefully acknowledges financial support from the European Research Council (grant agreement No. 716117, awarded to J. Maas) and from the Austrian Science Fund (FWF). His research was funded by the Austrian Science Fund (FWF) project 10.55776/F65 and project 10.55776/ESP208.\r\nRH, EK, and KTS gratefully acknowledge funding by the Hausdorff Center for Mathematics (project ID 390685813), and through project B03 within the CRC 1060 (project ID 211504053). RH and KTS also gratefully acknowledges financial support from the European Research Council through the ERC AdG ‘RicciBounds’ (grant agreement 694405).\r\nOpen access funding enabled and organized by Projekt DEAL.","date_created":"2024-12-08T23:01:56Z","citation":{"ama":"Dello Schiavo L, Herry R, Kopfer E, Sturm KT. Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous. <i>Mathematische Nachrichten</i>. 2025;298(1):244-281. doi:<a href=\"https://doi.org/10.1002/mana.202400169\">10.1002/mana.202400169</a>","chicago":"Dello Schiavo, Lorenzo, Ronan Herry, Eva Kopfer, and Karl Theodor Sturm. “Polyharmonic Fields and Liouville Quantum Gravity Measures on Tori of Arbitrary Dimension: From Discrete to Continuous.” <i>Mathematische Nachrichten</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/mana.202400169\">https://doi.org/10.1002/mana.202400169</a>.","ista":"Dello Schiavo L, Herry R, Kopfer E, Sturm KT. 2025. Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous. Mathematische Nachrichten. 298(1), 244–281.","mla":"Dello Schiavo, Lorenzo, et al. “Polyharmonic Fields and Liouville Quantum Gravity Measures on Tori of Arbitrary Dimension: From Discrete to Continuous.” <i>Mathematische Nachrichten</i>, vol. 298, no. 1, Wiley, 2025, pp. 244–81, doi:<a href=\"https://doi.org/10.1002/mana.202400169\">10.1002/mana.202400169</a>.","short":"L. Dello Schiavo, R. Herry, E. Kopfer, K.T. Sturm, Mathematische Nachrichten 298 (2025) 244–281.","apa":"Dello Schiavo, L., Herry, R., Kopfer, E., &#38; Sturm, K. T. (2025). Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous. <i>Mathematische Nachrichten</i>. Wiley. <a href=\"https://doi.org/10.1002/mana.202400169\">https://doi.org/10.1002/mana.202400169</a>","ieee":"L. Dello Schiavo, R. Herry, E. Kopfer, and K. T. Sturm, “Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous,” <i>Mathematische Nachrichten</i>, vol. 298, no. 1. Wiley, pp. 244–281, 2025."},"type":"journal_article","title":"Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","isi":1,"issue":"1"}]