[{"author":[{"last_name":"Wolf","full_name":"Wolf, Stephan","first_name":"Stephan"},{"last_name":"Mcmahon","full_name":"Mcmahon, Dino","first_name":"Dino"},{"full_name":"Lim, Ka","first_name":"Ka","last_name":"Lim"},{"orcid":"0000-0003-1122-3982","full_name":"Pull, Christopher","last_name":"Pull","first_name":"Christopher","id":"3C7F4840-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Clark","full_name":"Clark, Suzanne","first_name":"Suzanne"},{"last_name":"Paxton","full_name":"Paxton, Robert","first_name":"Robert"},{"last_name":"Osborne","first_name":"Juliet","full_name":"Osborne, Juliet"}],"date_created":"2021-08-11T14:17:53Z","month":"08","article_processing_charge":"No","citation":{"ama":"Wolf S, Mcmahon D, Lim K, et al. Supporting information. 2014. doi:<a href=\"https://doi.org/10.1371/journal.pone.0103989.s003\">10.1371/journal.pone.0103989.s003</a>","chicago":"Wolf, Stephan, Dino Mcmahon, Ka Lim, Christopher Pull, Suzanne Clark, Robert Paxton, and Juliet Osborne. “Supporting Information.” Public Library of Science, 2014. <a href=\"https://doi.org/10.1371/journal.pone.0103989.s003\">https://doi.org/10.1371/journal.pone.0103989.s003</a>.","apa":"Wolf, S., Mcmahon, D., Lim, K., Pull, C., Clark, S., Paxton, R., &#38; Osborne, J. (2014). Supporting information. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0103989.s003\">https://doi.org/10.1371/journal.pone.0103989.s003</a>","ieee":"S. Wolf <i>et al.</i>, “Supporting information.” Public Library of Science, 2014.","mla":"Wolf, Stephan, et al. <i>Supporting Information</i>. Public Library of Science, 2014, doi:<a href=\"https://doi.org/10.1371/journal.pone.0103989.s003\">10.1371/journal.pone.0103989.s003</a>.","ista":"Wolf S, Mcmahon D, Lim K, Pull C, Clark S, Paxton R, Osborne J. 2014. Supporting information, Public Library of Science, <a href=\"https://doi.org/10.1371/journal.pone.0103989.s003\">10.1371/journal.pone.0103989.s003</a>.","short":"S. Wolf, D. Mcmahon, K. Lim, C. Pull, S. Clark, R. Paxton, J. Osborne, (2014)."},"department":[{"_id":"SyCr"}],"title":"Supporting information","doi":"10.1371/journal.pone.0103989.s003","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"2086"}]},"date_updated":"2025-09-29T11:45:40Z","publisher":"Public Library of Science","status":"public","type":"research_data_reference","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","abstract":[{"text":"Detailed description of the experimental prodedures, data analyses and additional statistical analyses of the results.","lang":"eng"}],"day":"06","_id":"9888","oa_version":"Published Version","year":"2014"},{"date_published":"2014-06-03T00:00:00Z","citation":{"chicago":"Dhar, Riddhiman, Tobias Bergmiller, and Andreas Wagner. “Increased Gene Dosage Plays a Predominant Role in the Initial Stages of Evolution of Duplicate TEM-1 Beta Lactamase Genes.” <i>Evolution</i>. Wiley, 2014. <a href=\"https://doi.org/10.1111/evo.12373\">https://doi.org/10.1111/evo.12373</a>.","ama":"Dhar R, Bergmiller T, Wagner A. Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. <i>Evolution</i>. 2014;68(6):1775-1791. doi:<a href=\"https://doi.org/10.1111/evo.12373\">10.1111/evo.12373</a>","apa":"Dhar, R., Bergmiller, T., &#38; Wagner, A. (2014). Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. <i>Evolution</i>. Wiley. <a href=\"https://doi.org/10.1111/evo.12373\">https://doi.org/10.1111/evo.12373</a>","ieee":"R. Dhar, T. Bergmiller, and A. Wagner, “Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes,” <i>Evolution</i>, vol. 68, no. 6. Wiley, pp. 1775–1791, 2014.","mla":"Dhar, Riddhiman, et al. “Increased Gene Dosage Plays a Predominant Role in the Initial Stages of Evolution of Duplicate TEM-1 Beta Lactamase Genes.” <i>Evolution</i>, vol. 68, no. 6, Wiley, 2014, pp. 1775–91, doi:<a href=\"https://doi.org/10.1111/evo.12373\">10.1111/evo.12373</a>.","ista":"Dhar R, Bergmiller T, Wagner A. 2014. Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. Evolution. 68(6), 1775–1791.","short":"R. Dhar, T. Bergmiller, A. Wagner, Evolution 68 (2014) 1775–1791."},"month":"06","volume":68,"article_processing_charge":"No","date_created":"2021-08-17T09:03:09Z","publication_identifier":{"eissn":["1558-5646"],"issn":["0014-3820"]},"quality_controlled":"1","language":[{"iso":"eng"}],"pmid":1,"year":"2014","page":"1775-1791","_id":"9931","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_type":"original","isi":1,"intvolume":"        68","type":"journal_article","status":"public","publisher":"Wiley","date_updated":"2025-09-29T13:20:48Z","doi":"10.1111/evo.12373","acknowledgement":"We thank the Functional Genomics Center Zurich for its service in generating sequencing data, M. Ackermann and E. Hayden for helpful discussions, A. de Visser for comments on earlier versions of this manuscript, and M. Moser for help with quantitative PCR. This work was supported by Swiss National Science Foundation (grant 315230–129708), as well as through the YeastX project of SystemsX.ch, and the University Priority Research Program in Systems Biology at the University of Zurich. RD acknowledges support from the Forschungskredit program of the University of Zurich. The authors declare no conflict of interest.","title":"Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes","department":[{"_id":"CaGu"}],"external_id":{"isi":["000337558900019"],"pmid":["24495000"]},"author":[{"full_name":"Dhar, Riddhiman","last_name":"Dhar","first_name":"Riddhiman"},{"id":"2C471CFA-F248-11E8-B48F-1D18A9856A87","full_name":"Bergmiller, Tobias","last_name":"Bergmiller","first_name":"Tobias","orcid":"0000-0001-5396-4346"},{"last_name":"Wagner","full_name":"Wagner, Andreas","first_name":"Andreas"}],"oa_version":"None","day":"03","abstract":[{"text":"Gene duplication is important in evolution, because it provides new raw material for evolutionary adaptations. Several existing hypotheses about the causes of duplicate retention and diversification differ in their emphasis on gene dosage, subfunctionalization, and neofunctionalization. Little experimental data exist on the relative importance of gene expression changes and changes in coding regions for the evolution of duplicate genes. Furthermore, we do not know how strongly the environment could affect this importance. To address these questions, we performed evolution experiments with the TEM-1 beta lactamase gene in Escherichia coli to study the initial stages of duplicate gene evolution in the laboratory. We mimicked tandem duplication by inserting two copies of the TEM-1 gene on the same plasmid. We then subjected these copies to repeated cycles of mutagenesis and selection in various environments that contained antibiotics in different combinations and concentrations. Our experiments showed that gene dosage is the most important factor in the initial stages of duplicate gene evolution, and overshadows the importance of point mutations in the coding region.","lang":"eng"}],"issue":"6","publication":"Evolution","scopus_import":"1","publication_status":"published","related_material":{"record":[{"relation":"research_data","status":"public","id":"9932"}]}},{"type":"research_data_reference","publisher":"Dryad","status":"public","date_updated":"2025-09-29T13:20:47Z","doi":"10.5061/dryad.jc402","related_material":{"record":[{"id":"9931","status":"public","relation":"used_in_publication"}]},"_id":"9932","year":"2014","oa_version":"Published Version","abstract":[{"text":"Gene duplication is important in evolution, because it provides new raw material for evolutionary adaptations. Several existing hypotheses about the causes of duplicate retention and diversification differ in their emphasis on gene dosage, sub-functionalization, and neo-functionalization. Little experimental data exists on the relative importance of gene expression changes and changes in coding regions for the evolution of duplicate genes. Furthermore, we do not know how strongly the environment could affect this importance. To address these questions, we performed evolution experiments with the TEM-1 beta lactamase gene in E. coli to study the initial stages of duplicate gene evolution in the laboratory. We mimicked tandem duplication by inserting two copies of the TEM-1 gene on the same plasmid. We then subjected these copies to repeated cycles of mutagenesis and selection in various environments that contained antibiotics in different combinations and concentrations. Our experiments showed that gene dosage is the most important factor in the initial stages of duplicate gene evolution, and overshadows the importance of point mutations in the coding region.","lang":"eng"}],"day":"27","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","date_created":"2021-08-17T09:11:40Z","author":[{"full_name":"Dhar, Riddhiman","last_name":"Dhar","first_name":"Riddhiman"},{"orcid":"0000-0001-5396-4346","id":"2C471CFA-F248-11E8-B48F-1D18A9856A87","last_name":"Bergmiller","first_name":"Tobias","full_name":"Bergmiller, Tobias"},{"first_name":"Andreas","last_name":"Wagner","full_name":"Wagner, Andreas"}],"date_published":"2014-01-27T00:00:00Z","title":"Data from: Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes","main_file_link":[{"url":"https://doi.org/10.5061/dryad.jc402","open_access":"1"}],"month":"01","article_processing_charge":"No","oa":1,"department":[{"_id":"CaGu"}],"citation":{"ista":"Dhar R, Bergmiller T, Wagner A. 2014. Data from: Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes, Dryad, <a href=\"https://doi.org/10.5061/dryad.jc402\">10.5061/dryad.jc402</a>.","short":"R. Dhar, T. Bergmiller, A. Wagner, (2014).","chicago":"Dhar, Riddhiman, Tobias Bergmiller, and Andreas Wagner. “Data from: Increased Gene Dosage Plays a Predominant Role in the Initial Stages of Evolution of Duplicate TEM-1 Beta Lactamase Genes.” Dryad, 2014. <a href=\"https://doi.org/10.5061/dryad.jc402\">https://doi.org/10.5061/dryad.jc402</a>.","ama":"Dhar R, Bergmiller T, Wagner A. Data from: Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. 2014. doi:<a href=\"https://doi.org/10.5061/dryad.jc402\">10.5061/dryad.jc402</a>","apa":"Dhar, R., Bergmiller, T., &#38; Wagner, A. (2014). Data from: Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. Dryad. <a href=\"https://doi.org/10.5061/dryad.jc402\">https://doi.org/10.5061/dryad.jc402</a>","ieee":"R. Dhar, T. Bergmiller, and A. Wagner, “Data from: Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes.” Dryad, 2014.","mla":"Dhar, Riddhiman, et al. <i>Data from: Increased Gene Dosage Plays a Predominant Role in the Initial Stages of Evolution of Duplicate TEM-1 Beta Lactamase Genes</i>. Dryad, 2014, doi:<a href=\"https://doi.org/10.5061/dryad.jc402\">10.5061/dryad.jc402</a>."}},{"date_created":"2018-12-11T11:45:57Z","quality_controlled":"1","author":[{"first_name":"Doris","last_name":"Cadavid","full_name":"Cadavid, Doris"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","last_name":"Ibáñez","first_name":"Maria","orcid":"0000-0001-5013-2843"},{"first_name":"Umberto","last_name":"Anselmi Tamburini","full_name":"Anselmi Tamburini, Umberto"},{"full_name":"Durá, Oscar","last_name":"Durá","first_name":"Oscar"},{"full_name":"De La Torre, Marco","last_name":"De La Torre","first_name":"Marco"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"language":[{"iso":"eng"}],"title":"Thermoelectric properties of bottom up assembled Bi2S 3-xTex nanocomposites","date_published":"2014-01-01T00:00:00Z","citation":{"ista":"Cadavid D, Ibáñez M, Anselmi Tamburini U, Durá O, De La Torre M, Cabot A. 2014. Thermoelectric properties of bottom up assembled Bi2S 3-xTex nanocomposites. International Journal of Nanotechnology. 11(9–11), 773–784.","short":"D. Cadavid, M. Ibáñez, U. Anselmi Tamburini, O. Durá, M. De La Torre, A. Cabot, International Journal of Nanotechnology 11 (2014) 773–784.","apa":"Cadavid, D., Ibáñez, M., Anselmi Tamburini, U., Durá, O., De La Torre, M., &#38; Cabot, A. (2014). Thermoelectric properties of bottom up assembled Bi2S 3-xTex nanocomposites. <i>International Journal of Nanotechnology</i>. Inderscience Enterprises Limited . <a href=\"https://doi.org/10.1504/IJNT.2014.063787\">https://doi.org/10.1504/IJNT.2014.063787</a>","mla":"Cadavid, Doris, et al. “Thermoelectric Properties of Bottom up Assembled Bi2S 3-XTex Nanocomposites.” <i>International Journal of Nanotechnology</i>, vol. 11, no. 9–11, Inderscience Enterprises Limited , 2014, pp. 773–84, doi:<a href=\"https://doi.org/10.1504/IJNT.2014.063787\">10.1504/IJNT.2014.063787</a>.","ieee":"D. Cadavid, M. Ibáñez, U. Anselmi Tamburini, O. Durá, M. De La Torre, and A. Cabot, “Thermoelectric properties of bottom up assembled Bi2S 3-xTex nanocomposites,” <i>International Journal of Nanotechnology</i>, vol. 11, no. 9–11. Inderscience Enterprises Limited , pp. 773–784, 2014.","ama":"Cadavid D, Ibáñez M, Anselmi Tamburini U, Durá O, De La Torre M, Cabot A. Thermoelectric properties of bottom up assembled Bi2S 3-xTex nanocomposites. <i>International Journal of Nanotechnology</i>. 2014;11(9-11):773-784. doi:<a href=\"https://doi.org/10.1504/IJNT.2014.063787\">10.1504/IJNT.2014.063787</a>","chicago":"Cadavid, Doris, Maria Ibáñez, Umberto Anselmi Tamburini, Oscar Durá, Marco De La Torre, and Andreu Cabot. “Thermoelectric Properties of Bottom up Assembled Bi2S 3-XTex Nanocomposites.” <i>International Journal of Nanotechnology</i>. Inderscience Enterprises Limited , 2014. <a href=\"https://doi.org/10.1504/IJNT.2014.063787\">https://doi.org/10.1504/IJNT.2014.063787</a>."},"volume":11,"month":"01","article_processing_charge":"No","intvolume":"        11","date_updated":"2021-01-12T07:43:44Z","publication_status":"published","status":"public","type":"journal_article","extern":"1","publisher":"Inderscience Enterprises Limited ","publist_id":"7476","doi":"10.1504/IJNT.2014.063787","oa_version":"None","year":"2014","_id":"348","page":"773 - 784","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Bi2S3-xTex bulk nanocomposites with crystal domain sizes in the range from 50 nm to 100 nm were obtained from the reaction of Bi2S3 nanorods with Te powder. The thermoelectric properties of the obtained nanocomposites were analysed in the temperature range from 0°C to 300°C. We observed how the thermoelectric properties of the material improved with the annealing temperature, being a spark plasma sintering process needed to maintain the material nanostructuration while maximising its electrical properties. Finally thermoelectric dimensionless figures of merit ZT up to 0.42 were obtained before any charge carrier concentration optimisation. Copyright © 2014 Inderscience Enterprises Ltd.\r\n\r\n","lang":"eng"}],"issue":"9-11","publication":"International Journal of Nanotechnology","article_type":"original"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Thermoelectricity is a key technology with the potential to improve the efficiency of energy conversion processes, which may strongly benefit from advances in the field of nanotechnology. Nanostructured materials are very appealing for thermoelectric applications, but the full development of their potential requires precise control of their properties at the nanoscale. Bottom-up assembly of nanoparticles provides access to a three-dimensional composition control at the nanoscale not attainable in any other technology. In particular, colloidal nanoheterostructures are especially interesting building blocks for the bottom-up production of functional nanomaterials. In the present work, we use PbTe@PbS core-shell nanoparticles as building blocks for the bottom-up production of PbTe-PbS nanocomposites. We used a ligand exchange strategy and a hot press process to promote the electrical conductivity of the nanocomposite and to increase its density. These two approaches allowed us to improve the performance of bottom-up assembled PbTe-PbS bulk nanostructured materials. "}],"day":"21","article_type":"original","issue":"9-11","publication":"International Journal of Nanotechnology","year":"2014","oa_version":"None","page":"955 - 970","_id":"349","publist_id":"7477","doi":"10.1504/IJNT.2014.063802","intvolume":"        11","extern":"1","publisher":"Inderscience Enterprises Limited ","publication_status":"published","status":"public","type":"journal_article","date_updated":"2021-01-12T07:43:48Z","citation":{"apa":"Ortega, S., Ibáñez, M., Cadavid, D., &#38; Cabot, A. (2014). Bottom up processing of PbTe PbS thermoelectric nanocomposites. <i>International Journal of Nanotechnology</i>. Inderscience Enterprises Limited . <a href=\"https://doi.org/10.1504/IJNT.2014.063802\">https://doi.org/10.1504/IJNT.2014.063802</a>","ieee":"S. Ortega, M. Ibáñez, D. Cadavid, and A. Cabot, “Bottom up processing of PbTe PbS thermoelectric nanocomposites,” <i>International Journal of Nanotechnology</i>, vol. 11, no. 9–11. Inderscience Enterprises Limited , pp. 955–970, 2014.","mla":"Ortega, Silvia, et al. “Bottom up Processing of PbTe PbS Thermoelectric Nanocomposites.” <i>International Journal of Nanotechnology</i>, vol. 11, no. 9–11, Inderscience Enterprises Limited , 2014, pp. 955–70, doi:<a href=\"https://doi.org/10.1504/IJNT.2014.063802\">10.1504/IJNT.2014.063802</a>.","chicago":"Ortega, Silvia, Maria Ibáñez, Doris Cadavid, and Andreu Cabot. “Bottom up Processing of PbTe PbS Thermoelectric Nanocomposites.” <i>International Journal of Nanotechnology</i>. Inderscience Enterprises Limited , 2014. <a href=\"https://doi.org/10.1504/IJNT.2014.063802\">https://doi.org/10.1504/IJNT.2014.063802</a>.","ama":"Ortega S, Ibáñez M, Cadavid D, Cabot A. Bottom up processing of PbTe PbS thermoelectric nanocomposites. <i>International Journal of Nanotechnology</i>. 2014;11(9-11):955-970. doi:<a href=\"https://doi.org/10.1504/IJNT.2014.063802\">10.1504/IJNT.2014.063802</a>","ista":"Ortega S, Ibáñez M, Cadavid D, Cabot A. 2014. Bottom up processing of PbTe PbS thermoelectric nanocomposites. International Journal of Nanotechnology. 11(9–11), 955–970.","short":"S. Ortega, M. Ibáñez, D. Cadavid, A. Cabot, International Journal of Nanotechnology 11 (2014) 955–970."},"article_processing_charge":"No","month":"07","volume":11,"date_published":"2014-07-21T00:00:00Z","title":"Bottom up processing of PbTe PbS thermoelectric nanocomposites","quality_controlled":"1","author":[{"first_name":"Silvia","full_name":"Ortega, Silvia","last_name":"Ortega"},{"orcid":"0000-0001-5013-2843","first_name":"Maria","last_name":"Ibáñez","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Doris","last_name":"Cadavid","full_name":"Cadavid, Doris"},{"last_name":"Cabot","first_name":"Andreu","full_name":"Cabot, Andreu"}],"language":[{"iso":"eng"}],"date_created":"2018-12-11T11:45:57Z"},{"author":[{"first_name":"Wenhua","full_name":"Li, Wenhua","last_name":"Li"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","first_name":"Maria","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843"},{"full_name":"Cadavid, Doris","last_name":"Cadavid","first_name":"Doris"},{"first_name":"Reza","last_name":"Zamani","full_name":"Zamani, Reza"},{"first_name":"Javier","full_name":"Rubio Garcia, Javier","last_name":"Rubio Garcia"},{"full_name":"Gorsse, Stéphane","first_name":"Stéphane","last_name":"Gorsse"},{"first_name":"Joan","full_name":"Morante, Joan","last_name":"Morante"},{"full_name":"Arbiol, Jordi","first_name":"Jordi","last_name":"Arbiol"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"}],"title":"Colloidal synthesis and functional properties of quaternary Cu based semiconductors: Cu2HgGeSe4","main_file_link":[{"open_access":"1","url":"https://hal.archives-ouvertes.fr/hal-00959322/"}],"extern":"1","publication_status":"published","oa_version":"Submitted Version","day":"18","abstract":[{"lang":"eng","text":"Herein, a colloidal synthetic route to produce highly monodisperse Cu2HgGeSe4 (CHGSe) nanoparticles (NPs) is presented in detail. The high yield of the developed procedure allowed the production of CHGSe NPs at the gram scale. A thorough analysis of their structural and optical properties is shown. CHGSe NPs displayed poly-tetrahedral morphology and narrow size distributions with average size in the range of 10–40 nm and size dispersions below 10 %. A 1.6 eV optical band gap was measured by mean of UV–Vis. By adjusting the cation ratio, an effective control of their electrical conductivity is achieved. The prepared NPs are used as building blocks for the production of CHGSe bulk nanostructured materials. The thermoelectric properties of CHGSe nanomaterials are studied in the temperature range from 300 to 730 K. CHGSe nanomaterials reached electrical conductivities up to 5 × 104 S m−1, Seebeck coefficients above 100 μV K−1, and thermal conductivities below 1.0 W m−1 K−1 which translated into thermoelectric figures of merit up to 0.34 at 730 K."}],"issue":"3","publication":"Journal of Nanoparticle Research","date_created":"2018-12-11T11:45:58Z","quality_controlled":"1","language":[{"iso":"eng"}],"date_published":"2014-02-18T00:00:00Z","citation":{"mla":"Li, Wenhua, et al. “Colloidal Synthesis and Functional Properties of Quaternary Cu Based Semiconductors: Cu2HgGeSe4.” <i>Journal of Nanoparticle Research</i>, vol. 16, no. 3, Kluwer, 2014, doi:<a href=\"https://doi.org/10.1007/s11051-014-2297-2\">10.1007/s11051-014-2297-2</a>.","ieee":"W. Li <i>et al.</i>, “Colloidal synthesis and functional properties of quaternary Cu based semiconductors: Cu2HgGeSe4,” <i>Journal of Nanoparticle Research</i>, vol. 16, no. 3. Kluwer, 2014.","apa":"Li, W., Ibáñez, M., Cadavid, D., Zamani, R., Rubio Garcia, J., Gorsse, S., … Cabot, A. (2014). Colloidal synthesis and functional properties of quaternary Cu based semiconductors: Cu2HgGeSe4. <i>Journal of Nanoparticle Research</i>. Kluwer. <a href=\"https://doi.org/10.1007/s11051-014-2297-2\">https://doi.org/10.1007/s11051-014-2297-2</a>","chicago":"Li, Wenhua, Maria Ibáñez, Doris Cadavid, Reza Zamani, Javier Rubio Garcia, Stéphane Gorsse, Joan Morante, Jordi Arbiol, and Andreu Cabot. “Colloidal Synthesis and Functional Properties of Quaternary Cu Based Semiconductors: Cu2HgGeSe4.” <i>Journal of Nanoparticle Research</i>. Kluwer, 2014. <a href=\"https://doi.org/10.1007/s11051-014-2297-2\">https://doi.org/10.1007/s11051-014-2297-2</a>.","ama":"Li W, Ibáñez M, Cadavid D, et al. Colloidal synthesis and functional properties of quaternary Cu based semiconductors: Cu2HgGeSe4. <i>Journal of Nanoparticle Research</i>. 2014;16(3). doi:<a href=\"https://doi.org/10.1007/s11051-014-2297-2\">10.1007/s11051-014-2297-2</a>","short":"W. Li, M. Ibáñez, D. Cadavid, R. Zamani, J. Rubio Garcia, S. Gorsse, J. Morante, J. Arbiol, A. Cabot, Journal of Nanoparticle Research 16 (2014).","ista":"Li W, Ibáñez M, Cadavid D, Zamani R, Rubio Garcia J, Gorsse S, Morante J, Arbiol J, Cabot A. 2014. Colloidal synthesis and functional properties of quaternary Cu based semiconductors: Cu2HgGeSe4. Journal of Nanoparticle Research. 16(3)."},"oa":1,"month":"02","volume":16,"article_processing_charge":"No","intvolume":"        16","date_updated":"2021-01-12T07:43:53Z","status":"public","publisher":"Kluwer","type":"journal_article","publist_id":"7478","doi":"10.1007/s11051-014-2297-2","acknowledgement":"The research was supported by the European Regional Development Funds (ERDF, ‘‘FEDER Programa Competitivitat de Catalunya 2007–2013’’).","year":"2014","_id":"350","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original"},{"abstract":[{"lang":"eng","text":"We report on the photocatalytic hydrogen evolution under full-arc light irradiation of CuIn1-xGaxS2 wurtzite nanocrystals in the presence of SO3 2- and S2- as sacrificial reagents. We analyzed the hydrogen generation rate as a function of the Ga content and associated it with the energy band positions. For photocatalytic water splitting, the CuInS2 bandgap is slightly too low to efficiently overcome the reaction over-potential. The presence of Ga shifts up the CuInS2 conduction band edge providing a larger driving force for photogenerated carriers to activate the water splitting reduction reaction. The larger the Ga content, the more energetically favorable the electron injection, and thus a more efficient use of the photogenerated carriers is reached. However, the band gap increase associated with the Ga incorporation reduces the concentration of photogenerated carriers available for water splitting, and consequently a lower hydrogen conversion rate is obtained for very high Ga contents. The optimum Ga concentration was experimentally found at CuIn0.3Ga0.7S2. "}],"day":"21","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publication":"Journal of Materials Chemistry A","issue":"31","year":"2014","oa_version":"None","page":"12317 - 12322","_id":"355","publist_id":"7471","acknowledgement":"The research was supported by the European Regional Development\r\nFunds (ERDF, “FEDER Programa Competitivitat de\r\nCatalunya 2007-2013”) and the Framework 7 program under\r\nproject SCALENANO (FP7-NMP-ENERGY-2011-284486).","doi":"10.1039/c4ta01315h","intvolume":"         2","status":"public","publisher":"Royal Society of Chemistry","extern":"1","type":"journal_article","publication_status":"published","date_updated":"2021-01-12T07:44:14Z","citation":{"short":"X. Yu, X. An, A. Shavel, M. Ibáñez, A. Cabot, Journal of Materials Chemistry A 2 (2014) 12317–12322.","ista":"Yu X, An X, Shavel A, Ibáñez M, Cabot A. 2014. The effect of the Ga content on the photocatalytic hydrogen evolution of CuIn1-xGaxS2 nanocrystals. Journal of Materials Chemistry A. 2(31), 12317–12322.","chicago":"Yu, Xuelian, Xiaoqiang An, Alexey Shavel, Maria Ibáñez, and Andreu Cabot. “The Effect of the Ga Content on the Photocatalytic Hydrogen Evolution of CuIn1-XGaxS2 Nanocrystals.” <i>Journal of Materials Chemistry A</i>. Royal Society of Chemistry, 2014. <a href=\"https://doi.org/10.1039/c4ta01315h\">https://doi.org/10.1039/c4ta01315h</a>.","ama":"Yu X, An X, Shavel A, Ibáñez M, Cabot A. The effect of the Ga content on the photocatalytic hydrogen evolution of CuIn1-xGaxS2 nanocrystals. <i>Journal of Materials Chemistry A</i>. 2014;2(31):12317-12322. doi:<a href=\"https://doi.org/10.1039/c4ta01315h\">10.1039/c4ta01315h</a>","mla":"Yu, Xuelian, et al. “The Effect of the Ga Content on the Photocatalytic Hydrogen Evolution of CuIn1-XGaxS2 Nanocrystals.” <i>Journal of Materials Chemistry A</i>, vol. 2, no. 31, Royal Society of Chemistry, 2014, pp. 12317–22, doi:<a href=\"https://doi.org/10.1039/c4ta01315h\">10.1039/c4ta01315h</a>.","ieee":"X. Yu, X. An, A. Shavel, M. Ibáñez, and A. Cabot, “The effect of the Ga content on the photocatalytic hydrogen evolution of CuIn1-xGaxS2 nanocrystals,” <i>Journal of Materials Chemistry A</i>, vol. 2, no. 31. Royal Society of Chemistry, pp. 12317–12322, 2014.","apa":"Yu, X., An, X., Shavel, A., Ibáñez, M., &#38; Cabot, A. (2014). The effect of the Ga content on the photocatalytic hydrogen evolution of CuIn1-xGaxS2 nanocrystals. <i>Journal of Materials Chemistry A</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/c4ta01315h\">https://doi.org/10.1039/c4ta01315h</a>"},"month":"08","article_processing_charge":"No","volume":2,"date_published":"2014-08-21T00:00:00Z","title":"The effect of the Ga content on the photocatalytic hydrogen evolution of CuIn1-xGaxS2 nanocrystals","quality_controlled":"1","language":[{"iso":"eng"}],"author":[{"first_name":"Xuelian","full_name":"Yu, Xuelian","last_name":"Yu"},{"last_name":"An","first_name":"Xiaoqiang","full_name":"An, Xiaoqiang"},{"last_name":"Shavel","first_name":"Alexey","full_name":"Shavel, Alexey"},{"orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","last_name":"Ibáñez","first_name":"Maria"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"date_created":"2018-12-11T11:45:59Z"},{"issue":"20","publication":"CrystEngComm","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"28","abstract":[{"text":"Near-resonant Raman scattering measurements of zinc sulfide nanoparticles and thin films have been made and correlated to grain and particle size, respectively, using a 325 nm wavelength excitation source. The area ratios between the first, second, and third order peaks of ZnS identified as the T 2(LO) mode decrease with increasing ZnS grain size. This is an effect attributed to changes in the bandgap energy from quantum confinement due to the varying grain size between the films/particles, as noted by a shift in the room temperature photoluminescence emission corresponding to the free exciton emission energy. While Raman scattering spectroscopy is typically limited to identification of phases and their crystalline properties, it is possible to attain more than such straightforward information by calibrating the spectral features to variations between sets of samples. These results open the possibility of making a quantitative grain size estimation in ZnS thin films and nanostructures, as well as in other material systems where ZnS may be expected as a secondary phase, such as Cu2ZnSnS4. Additionally, more commonly used excitation wavelengths for Raman scattering, such as 514 and 532 nm, are shown to be of limited use in characterizing ZnS thin films due to the extremely low Raman scattering efficiency of ZnS in films with sub-micron thicknesses. ","lang":"eng"}],"_id":"357","page":"4120 - 4125","oa_version":"None","year":"2014","doi":"10.1039/c3ce42578a","acknowledgement":"This research was supported by the People Programme\r\n(Marie Curie Actions) of the European Union's Seventh Framework\r\nProgramme under REA grant agreement number 269167\r\n(PVICOKEST) and the Spanish Ministerio de Economía y\r\nCompetividad (MINECO) under KEST-PV (ref. ENE2010-\r\n121541-C03-01/02). Authors from IREC belong to the M-2E\r\n(Electronic Materials for Energy) Consolidated Research\r\nGroup and the XaRMAE Network of Excellence on Materials\r\nfor Energy of the “Generalitat de Catalunya”. A. Fairbrother\r\nthanks the MINECO for support via the FPU program\r\n(FPU12/05508), V. Izquierdo for the Juan de la Cierva program\r\n(JCI-2011-10782), and E. Saucedo for the Ramón y Cajal\r\nprogram (RYC-2011-09212).","publist_id":"7473","date_updated":"2021-01-12T07:44:22Z","extern":"1","publication_status":"published","publisher":"Royal Society of Chemistry","status":"public","type":"journal_article","intvolume":"        16","volume":16,"article_processing_charge":"No","month":"05","citation":{"ista":"Fairbrother A, Izquierdo Roca V, Fontané X, Ibáñez M, Cabot A, Saucedo E, Pérez Rodríguez A. 2014. ZnS grain size effects on near-resonant Raman scattering: Optical non-destructive grain size estimation. CrystEngComm. 16(20), 4120–4125.","short":"A. Fairbrother, V. Izquierdo Roca, X. Fontané, M. Ibáñez, A. Cabot, E. Saucedo, A. Pérez Rodríguez, CrystEngComm 16 (2014) 4120–4125.","chicago":"Fairbrother, Andrew, Victor Izquierdo Roca, Xavier Fontané, Maria Ibáñez, Andreu Cabot, Edgardo Saucedo, and Alejandro Pérez Rodríguez. “ZnS Grain Size Effects on Near-Resonant Raman Scattering: Optical Non-Destructive Grain Size Estimation.” <i>CrystEngComm</i>. Royal Society of Chemistry, 2014. <a href=\"https://doi.org/10.1039/c3ce42578a\">https://doi.org/10.1039/c3ce42578a</a>.","ama":"Fairbrother A, Izquierdo Roca V, Fontané X, et al. ZnS grain size effects on near-resonant Raman scattering: Optical non-destructive grain size estimation. <i>CrystEngComm</i>. 2014;16(20):4120-4125. doi:<a href=\"https://doi.org/10.1039/c3ce42578a\">10.1039/c3ce42578a</a>","apa":"Fairbrother, A., Izquierdo Roca, V., Fontané, X., Ibáñez, M., Cabot, A., Saucedo, E., &#38; Pérez Rodríguez, A. (2014). ZnS grain size effects on near-resonant Raman scattering: Optical non-destructive grain size estimation. <i>CrystEngComm</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/c3ce42578a\">https://doi.org/10.1039/c3ce42578a</a>","ieee":"A. Fairbrother <i>et al.</i>, “ZnS grain size effects on near-resonant Raman scattering: Optical non-destructive grain size estimation,” <i>CrystEngComm</i>, vol. 16, no. 20. Royal Society of Chemistry, pp. 4120–4125, 2014.","mla":"Fairbrother, Andrew, et al. “ZnS Grain Size Effects on Near-Resonant Raman Scattering: Optical Non-Destructive Grain Size Estimation.” <i>CrystEngComm</i>, vol. 16, no. 20, Royal Society of Chemistry, 2014, pp. 4120–25, doi:<a href=\"https://doi.org/10.1039/c3ce42578a\">10.1039/c3ce42578a</a>."},"title":"ZnS grain size effects on near-resonant Raman scattering: Optical non-destructive grain size estimation","date_published":"2014-05-28T00:00:00Z","author":[{"full_name":"Fairbrother, Andrew","first_name":"Andrew","last_name":"Fairbrother"},{"full_name":"Izquierdo Roca, Victor","first_name":"Victor","last_name":"Izquierdo Roca"},{"last_name":"Fontané","first_name":"Xavier","full_name":"Fontané, Xavier"},{"orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","last_name":"Ibáñez"},{"last_name":"Cabot","full_name":"Cabot, Andreu","first_name":"Andreu"},{"full_name":"Saucedo, Edgardo","first_name":"Edgardo","last_name":"Saucedo"},{"last_name":"Pérez Rodríguez","first_name":"Alejandro","full_name":"Pérez Rodríguez, Alejandro"}],"language":[{"iso":"eng"}],"quality_controlled":"1","date_created":"2018-12-11T11:46:00Z"},{"title":"In situ study of ethanol electrooxidation on monodispersed Pt inf 3 inf Sn nanoparticles","date_published":"2014-03-03T00:00:00Z","citation":{"ista":"Herranz T, Ibáñez M, Gómez De La Fuente J, Pérez Alonso F, Peña M, Cabot A, Rojas S. 2014. In situ study of ethanol electrooxidation on monodispersed Pt inf 3 inf Sn nanoparticles. ChemElectroChem. 1(5), 885–895.","short":"T. Herranz, M. Ibáñez, J. Gómez De La Fuente, F. Pérez Alonso, M. Peña, A. Cabot, S. Rojas, ChemElectroChem 1 (2014) 885–895.","apa":"Herranz, T., Ibáñez, M., Gómez De La Fuente, J., Pérez Alonso, F., Peña, M., Cabot, A., &#38; Rojas, S. (2014). In situ study of ethanol electrooxidation on monodispersed Pt inf 3 inf Sn nanoparticles. <i>ChemElectroChem</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/celc.201300254\">https://doi.org/10.1002/celc.201300254</a>","ieee":"T. Herranz <i>et al.</i>, “In situ study of ethanol electrooxidation on monodispersed Pt inf 3 inf Sn nanoparticles,” <i>ChemElectroChem</i>, vol. 1, no. 5. Wiley-Blackwell, pp. 885–895, 2014.","mla":"Herranz, Tirma, et al. “In Situ Study of Ethanol Electrooxidation on Monodispersed Pt Inf 3 Inf Sn Nanoparticles.” <i>ChemElectroChem</i>, vol. 1, no. 5, Wiley-Blackwell, 2014, pp. 885–95, doi:<a href=\"https://doi.org/10.1002/celc.201300254\">10.1002/celc.201300254</a>.","chicago":"Herranz, Tirma, Maria Ibáñez, José Gómez De La Fuente, Francisco Pérez Alonso, Miguel Peña, Andreu Cabot, and Sergio Rojas. “In Situ Study of Ethanol Electrooxidation on Monodispersed Pt Inf 3 Inf Sn Nanoparticles.” <i>ChemElectroChem</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.1002/celc.201300254\">https://doi.org/10.1002/celc.201300254</a>.","ama":"Herranz T, Ibáñez M, Gómez De La Fuente J, et al. In situ study of ethanol electrooxidation on monodispersed Pt inf 3 inf Sn nanoparticles. <i>ChemElectroChem</i>. 2014;1(5):885-895. doi:<a href=\"https://doi.org/10.1002/celc.201300254\">10.1002/celc.201300254</a>"},"volume":1,"article_processing_charge":"No","month":"03","date_created":"2018-12-11T11:46:00Z","quality_controlled":"1","language":[{"iso":"eng"}],"author":[{"full_name":"Herranz, Tirma","last_name":"Herranz","first_name":"Tirma"},{"full_name":"Ibáñez, Maria","first_name":"Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5013-2843"},{"full_name":"Gómez De La Fuente, José","last_name":"Gómez De La Fuente","first_name":"José"},{"last_name":"Pérez Alonso","first_name":"Francisco","full_name":"Pérez Alonso, Francisco"},{"full_name":"Peña, Miguel","first_name":"Miguel","last_name":"Peña"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"},{"full_name":"Rojas, Sergio","last_name":"Rojas","first_name":"Sergio"}],"oa_version":"None","year":"2014","_id":"358","page":"885 - 895","day":"03","abstract":[{"lang":"eng","text":"Monodispersed Pt3Sn nanoparticles were prepared through a mild thermal synthesis in the presence of surfactants. The performance of Pt3Sn for the electrooxidation of ethanol and adsorbed carbon monoxide (COad) in acid medium was studied by a combination of electrochemical and insitu spectroscopic methods, namely, infrared reflection absorption spectroscopy and differential electrochemical mass spectrometry (DEMS), and the results were compared to those obtained with the use of Pt black. The formation of the Pt3Sn solid solution promoted the oxidation of COad at less-positive potentials than those required for Pt black. Also, the electrooxidation of ethanol, especially at lower potentials, was more favorable with Pt3Sn, as deduced from the higher faradaic currents recorded during the ethanol oxidation reaction (EOR). However, the distribution of products as deduced by DEMS analysis suggested that the formation of C1 products, CO2 inclusive, is less significant on Pt3Sn than on Pt. In fact, the higher faradaic current recorded with the former catalyst can be attributed to the greater amounts of acetaldehyde and acetic acid formed. After the EOR, the surface of both Pt and Pt3Sn remained covered by ethanol adsorbates. Whereas C2 fragments were the main adsorbates at the surface of Pt3Sn after the EOR, both C1 and C2 species remained adsorbed at Pt black."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"ChemElectroChem","issue":"5","article_type":"original","intvolume":"         1","date_updated":"2021-01-12T07:44:26Z","publisher":"Wiley-Blackwell","extern":"1","status":"public","publication_status":"published","type":"journal_article","publist_id":"7474","acknowledgement":"The Spanish Ministry of Science and Innovation (Project ENE2010–15381) and the CSIC (Project 201080E116) are acknowledged for financial support.","doi":"10.1002/celc.201300254"},{"_id":"359","page":"2290 - 2301","oa_version":"None","year":"2014","publication":"ACS Nano","issue":"3","article_type":"original","day":"25","abstract":[{"text":"An appropriate way of realizing property nanoengineering in complex quaternary chalcogenide nanocrystals is presented for Cu2Cd xSnSey(CCTSe) polypods. The pivotal role of the polarity in determining morphology, growth, and the polytypic branching mechanism is demonstrated. Polarity is considered to be responsible for the formation of an initial seed that takes the form of a tetrahedron with four cation-polar facets. Size and shape confinement of the intermediate pentatetrahedral seed is also attributed to polarity, as their external facets are anion-polar. The final polypod extensions also branch out as a result of a cation-polarity-driven mechanism. Aberration-corrected scanning transmission electron microscopy is used to identify stannite cation ordering, while ab initio studies are used to show the influence of cation ordering/distortion, stoichiometry, and polytypic structural change on the electronic band structure.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T07:44:30Z","publication_status":"published","status":"public","publisher":"American Chemical Society","extern":"1","type":"journal_article","intvolume":"         8","acknowledgement":"The research leading to these results has received funding from the European Union Seventh Framework Programme under grant agreement 312483-ESTEEM2 (Integrated Infrastructure InitiativeI3) for using advance electron microscopes at ER-C Jülich. J.A. acknowledges the funding from the Spanish MICINN project MAT2010-15138 (COPEON) and Generalitat de Catalunya 2009 SGR 770. R.R.Z. acknowledges the former. The authors would also like to thank the TEM facilities in Serveis Cientificotecnics from Universitat de Barcelona. N.G.-C. acknowledges the Spanish MECD for her Ph.D. grant in the FPU program. JR and RZ acknowledge funding from MULTICAT and NANOENESTO projects.","doi":"10.1021/nn405747h","publist_id":"7475","title":"Polarity-driven polytypic branching in Cu-based quaternary chalcogenide nanostructures","date_published":"2014-03-25T00:00:00Z","volume":8,"month":"03","article_processing_charge":"No","citation":{"chicago":"Zamani, Reza, Maria Ibáñez, Martina Luysberg, Nuria García Castelló, Lothar Houben, Joan Prades, Vincenzo Grillo, et al. “Polarity-Driven Polytypic Branching in Cu-Based Quaternary Chalcogenide Nanostructures.” <i>ACS Nano</i>. American Chemical Society, 2014. <a href=\"https://doi.org/10.1021/nn405747h\">https://doi.org/10.1021/nn405747h</a>.","ama":"Zamani R, Ibáñez M, Luysberg M, et al. Polarity-driven polytypic branching in Cu-based quaternary chalcogenide nanostructures. <i>ACS Nano</i>. 2014;8(3):2290-2301. doi:<a href=\"https://doi.org/10.1021/nn405747h\">10.1021/nn405747h</a>","apa":"Zamani, R., Ibáñez, M., Luysberg, M., García Castelló, N., Houben, L., Prades, J., … Arbiol, J. (2014). Polarity-driven polytypic branching in Cu-based quaternary chalcogenide nanostructures. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/nn405747h\">https://doi.org/10.1021/nn405747h</a>","mla":"Zamani, Reza, et al. “Polarity-Driven Polytypic Branching in Cu-Based Quaternary Chalcogenide Nanostructures.” <i>ACS Nano</i>, vol. 8, no. 3, American Chemical Society, 2014, pp. 2290–301, doi:<a href=\"https://doi.org/10.1021/nn405747h\">10.1021/nn405747h</a>.","ieee":"R. Zamani <i>et al.</i>, “Polarity-driven polytypic branching in Cu-based quaternary chalcogenide nanostructures,” <i>ACS Nano</i>, vol. 8, no. 3. American Chemical Society, pp. 2290–2301, 2014.","ista":"Zamani R, Ibáñez M, Luysberg M, García Castelló N, Houben L, Prades J, Grillo V, Dunin Borkowski R, Morante J, Cabot A, Arbiol J. 2014. Polarity-driven polytypic branching in Cu-based quaternary chalcogenide nanostructures. ACS Nano. 8(3), 2290–2301.","short":"R. Zamani, M. Ibáñez, M. Luysberg, N. García Castelló, L. Houben, J. Prades, V. Grillo, R. Dunin Borkowski, J. Morante, A. Cabot, J. Arbiol, ACS Nano 8 (2014) 2290–2301."},"date_created":"2018-12-11T11:46:01Z","author":[{"full_name":"Zamani, Reza","last_name":"Zamani","first_name":"Reza"},{"last_name":"Ibáñez","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843"},{"full_name":"Luysberg, Martina","last_name":"Luysberg","first_name":"Martina"},{"first_name":"Nuria","full_name":"García Castelló, Nuria","last_name":"García Castelló"},{"full_name":"Houben, Lothar","last_name":"Houben","first_name":"Lothar"},{"full_name":"Prades, Joan","first_name":"Joan","last_name":"Prades"},{"last_name":"Grillo","full_name":"Grillo, Vincenzo","first_name":"Vincenzo"},{"last_name":"Dunin Borkowski","first_name":"Rafal","full_name":"Dunin Borkowski, Rafal"},{"last_name":"Morante","first_name":"Joan","full_name":"Morante, Joan"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"},{"first_name":"Jordi","full_name":"Arbiol, Jordi","last_name":"Arbiol"}],"language":[{"iso":"eng"}],"quality_controlled":"1"},{"day":"01","abstract":[{"lang":"eng","text":"We introduce algorithms for the computation of homology, cohomology, and related operations on cubical cell complexes, using the technique based on a chain contraction from the original chain complex to a reduced one that represents its homology. This work is based on previous results for simplicial complexes, and uses Serre’s diagonalization for cubical cells. An implementation in C++ of the introduced algorithms is available at http://www.pawelpilarczyk.com/chaincon/ together with some examples. The paper is self-contained as much as possible, and is written at a very elementary level, so that basic knowledge of algebraic topology should be sufficient to follow it."}],"publication":"Advances in Computational Mathematics","issue":"1","year":"2014","_id":"451","page":"253 - 275","publist_id":"7371","doi":"10.1007/s10444-014-9356-1","acknowledgement":"This research was partially supported from Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE – Programa Operacional Factores de Compe titividade (POFC) and from the Portuguese national funds through Fundacaoparaa Ciencia e a Tecnologia (FCT) in the framework of the research project FCOMP-01-0124-FEDER-010645(ref. FCT PTDC/MAT/098871/2008), as well as from the funds distributed through the European Science Foundation (ESF) Research Networking Programme on “Applied and Computational Algebraic Topology” (ACAT). P.Real was additionally supported by the Spanish Ministry of Science and Innovation, project no. MTM2009-12716. ","intvolume":"        41","date_updated":"2021-01-12T07:59:20Z","publication_status":"published","publisher":"Kluwer","extern":1,"status":"public","type":"journal_article","citation":{"chicago":"Pilarczyk, Pawel, and Pedro Real. “Computation of Cubical Homology, Cohomology, and (Co)Homological Operations via Chain Contraction.” <i>Advances in Computational Mathematics</i>. Kluwer, 2014. <a href=\"https://doi.org/10.1007/s10444-014-9356-1\">https://doi.org/10.1007/s10444-014-9356-1</a>.","ama":"Pilarczyk P, Real P. Computation of cubical homology, cohomology, and (co)homological operations via chain contraction. <i>Advances in Computational Mathematics</i>. 2014;41(1):253-275. doi:<a href=\"https://doi.org/10.1007/s10444-014-9356-1\">10.1007/s10444-014-9356-1</a>","apa":"Pilarczyk, P., &#38; Real, P. (2014). Computation of cubical homology, cohomology, and (co)homological operations via chain contraction. <i>Advances in Computational Mathematics</i>. Kluwer. <a href=\"https://doi.org/10.1007/s10444-014-9356-1\">https://doi.org/10.1007/s10444-014-9356-1</a>","ieee":"P. Pilarczyk and P. Real, “Computation of cubical homology, cohomology, and (co)homological operations via chain contraction,” <i>Advances in Computational Mathematics</i>, vol. 41, no. 1. Kluwer, pp. 253–275, 2014.","mla":"Pilarczyk, Pawel, and Pedro Real. “Computation of Cubical Homology, Cohomology, and (Co)Homological Operations via Chain Contraction.” <i>Advances in Computational Mathematics</i>, vol. 41, no. 1, Kluwer, 2014, pp. 253–75, doi:<a href=\"https://doi.org/10.1007/s10444-014-9356-1\">10.1007/s10444-014-9356-1</a>.","ista":"Pilarczyk P, Real P. 2014. Computation of cubical homology, cohomology, and (co)homological operations via chain contraction. Advances in Computational Mathematics. 41(1), 253–275.","short":"P. Pilarczyk, P. Real, Advances in Computational Mathematics 41 (2014) 253–275."},"oa":1,"main_file_link":[{"open_access":"1","url":"https://idus.us.es/xmlui/handle/11441/38719"}],"month":"01","volume":41,"title":"Computation of cubical homology, cohomology, and (co)homological operations via chain contraction","date_published":"2014-01-01T00:00:00Z","quality_controlled":0,"author":[{"id":"3768D56A-F248-11E8-B48F-1D18A9856A87","last_name":"Pilarczyk","first_name":"Pawel","full_name":"Pawel Pilarczyk"},{"full_name":"Real, Pedro","last_name":"Real","first_name":"Pedro"}],"date_created":"2018-12-11T11:46:33Z"},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"year":"2014","_id":"2084","page":"1713 - 1726","publist_id":"4953","doi":"10.15252/embj.201387695","acknowledgement":"European Union Seventh Framework Programme; Human Frontier Science Program; Oesterreichische Nationalbank Anniversary Fund 14211; Austrian Research Promotion Agency; FemTech","intvolume":"        33","date_updated":"2026-04-08T14:11:53Z","status":"public","type":"journal_article","publisher":"Wiley-Blackwell","citation":{"short":"M. Grusch, K. Schelch, R. Riedler, E. Gschaider-Reichhart, C. Differ, W. Berger, Á. Inglés Prieto, H.L. Janovjak, EMBO Journal 33 (2014) 1713–1726.","ista":"Grusch M, Schelch K, Riedler R, Gschaider-Reichhart E, Differ C, Berger W, Inglés Prieto Á, Janovjak HL. 2014. Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. EMBO Journal. 33(15), 1713–1726.","mla":"Grusch, Michael, et al. “Spatio-Temporally Precise Activation of Engineered Receptor Tyrosine Kinases by Light.” <i>EMBO Journal</i>, vol. 33, no. 15, Wiley-Blackwell, 2014, pp. 1713–26, doi:<a href=\"https://doi.org/10.15252/embj.201387695\">10.15252/embj.201387695</a>.","ieee":"M. Grusch <i>et al.</i>, “Spatio-temporally precise activation of engineered receptor tyrosine kinases by light,” <i>EMBO Journal</i>, vol. 33, no. 15. Wiley-Blackwell, pp. 1713–1726, 2014.","apa":"Grusch, M., Schelch, K., Riedler, R., Gschaider-Reichhart, E., Differ, C., Berger, W., … Janovjak, H. L. (2014). Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. <i>EMBO Journal</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.15252/embj.201387695\">https://doi.org/10.15252/embj.201387695</a>","chicago":"Grusch, Michael, Karin Schelch, Robert Riedler, Eva Gschaider-Reichhart, Christopher Differ, Walter Berger, Álvaro Inglés Prieto, and Harald L Janovjak. “Spatio-Temporally Precise Activation of Engineered Receptor Tyrosine Kinases by Light.” <i>EMBO Journal</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.15252/embj.201387695\">https://doi.org/10.15252/embj.201387695</a>.","ama":"Grusch M, Schelch K, Riedler R, et al. Spatio-temporally precise activation of engineered receptor tyrosine kinases by light. <i>EMBO Journal</i>. 2014;33(15):1713-1726. doi:<a href=\"https://doi.org/10.15252/embj.201387695\">10.15252/embj.201387695</a>"},"oa":1,"volume":33,"month":"07","article_processing_charge":"No","date_published":"2014-07-01T00:00:00Z","quality_controlled":"1","language":[{"iso":"eng"}],"date_created":"2018-12-11T11:55:37Z","day":"01","abstract":[{"lang":"eng","text":"Receptor tyrosine kinases (RTKs) are a large family of cell surface receptors that sense growth factors and hormones and regulate a variety of cell behaviours in health and disease. Contactless activation of RTKs with spatial and temporal precision is currently not feasible. Here, we generated RTKs that are insensitive to endogenous ligands but can be selectively activated by low-intensity blue light. We screened light-oxygen-voltage (LOV)-sensing domains for their ability to activate RTKs by light-activated dimerization. Incorporation of LOV domains found in aureochrome photoreceptors of stramenopiles resulted in robust activation of the fibroblast growth factor receptor 1 (FGFR1), epidermal growth factor receptor (EGFR) and rearranged during transfection (RET). In human cancer and endothelial cells, light induced cellular signalling with spatial and temporal precision. Furthermore, light faithfully mimicked complex mitogenic and morphogenic cell behaviour induced by growth factors. RTKs under optical control (Opto-RTKs) provide a powerful optogenetic approach to actuate cellular signals and manipulate cell behaviour."}],"publication":"EMBO Journal","issue":"15","oa_version":"Submitted Version","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"418"}]},"scopus_import":"1","corr_author":"1","publication_status":"published","department":[{"_id":"HaJa"}],"main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194103/","open_access":"1"}],"title":"Spatio-temporally precise activation of engineered receptor tyrosine kinases by light","author":[{"full_name":"Grusch, Michael","first_name":"Michael","last_name":"Grusch"},{"first_name":"Karin","last_name":"Schelch","full_name":"Schelch, Karin"},{"first_name":"Robert","last_name":"Riedler","full_name":"Riedler, Robert"},{"orcid":"0000-0002-7218-7738","full_name":"Gschaider-Reichhart, Eva","first_name":"Eva","last_name":"Gschaider-Reichhart","id":"3FEE232A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Differ","first_name":"Christopher","full_name":"Differ, Christopher"},{"full_name":"Berger, Walter","first_name":"Walter","last_name":"Berger"},{"last_name":"Inglés Prieto","id":"2A9DB292-F248-11E8-B48F-1D18A9856A87","full_name":"Inglés Prieto, Álvaro","first_name":"Álvaro","orcid":"0000-0002-5409-8571"},{"first_name":"Harald L","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","full_name":"Janovjak, Harald L","last_name":"Janovjak","orcid":"0000-0002-8023-9315"}],"external_id":{"isi":["000339917000011"]}},{"oa":1,"volume":8616,"month":"01","citation":{"mla":"Gazi, Peter, et al. <i>The Exact PRF-Security of NMAC and HMAC</i>. Edited by Juan Garay and Rosario Gennaro, vol. 8616, no. 1, Springer, 2014, pp. 113–30, doi:<a href=\"https://doi.org/10.1007/978-3-662-44371-2_7\">10.1007/978-3-662-44371-2_7</a>.","ieee":"P. Gazi, K. Z. Pietrzak, and M. Rybar, “The exact PRF-security of NMAC and HMAC,” presented at the CRYPTO: International Cryptology Conference, Santa Barbara, USA, 2014, vol. 8616, no. 1, pp. 113–130.","apa":"Gazi, P., Pietrzak, K. Z., &#38; Rybar, M. (2014). The exact PRF-security of NMAC and HMAC. In J. Garay &#38; R. Gennaro (Eds.) (Vol. 8616, pp. 113–130). Presented at the CRYPTO: International Cryptology Conference, Santa Barbara, USA: Springer. <a href=\"https://doi.org/10.1007/978-3-662-44371-2_7\">https://doi.org/10.1007/978-3-662-44371-2_7</a>","ama":"Gazi P, Pietrzak KZ, Rybar M. The exact PRF-security of NMAC and HMAC. In: Garay J, Gennaro R, eds. Vol 8616. Springer; 2014:113-130. doi:<a href=\"https://doi.org/10.1007/978-3-662-44371-2_7\">10.1007/978-3-662-44371-2_7</a>","chicago":"Gazi, Peter, Krzysztof Z Pietrzak, and Michal Rybar. “The Exact PRF-Security of NMAC and HMAC.” edited by Juan Garay and Rosario Gennaro, 8616:113–30. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-662-44371-2_7\">https://doi.org/10.1007/978-3-662-44371-2_7</a>.","short":"P. Gazi, K.Z. Pietrzak, M. Rybar, in:, J. Garay, R. Gennaro (Eds.), Springer, 2014, pp. 113–130.","ista":"Gazi P, Pietrzak KZ, Rybar M. 2014. The exact PRF-security of NMAC and HMAC. CRYPTO: International Cryptology Conference, LNCS, vol. 8616, 113–130."},"file_date_updated":"2020-07-14T12:45:28Z","date_published":"2014-01-01T00:00:00Z","editor":[{"full_name":"Garay, Juan","last_name":"Garay","first_name":"Juan"},{"full_name":"Gennaro, Rosario","first_name":"Rosario","last_name":"Gennaro"}],"language":[{"iso":"eng"}],"quality_controlled":"1","date_created":"2018-12-11T11:55:36Z","conference":{"location":"Santa Barbara, USA","start_date":"2014-08-17","end_date":"2014-08-21","name":"CRYPTO: International Cryptology Conference"},"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","_id":"2082","page":"113 - 130","year":"2014","doi":"10.1007/978-3-662-44371-2_7","publist_id":"4955","date_updated":"2026-04-08T14:18:39Z","publisher":"Springer","status":"public","type":"conference","intvolume":"      8616","file":[{"file_name":"IST-2016-682-v1+1_578.pdf","date_created":"2018-12-12T10:13:17Z","access_level":"open_access","date_updated":"2020-07-14T12:45:28Z","relation":"main_file","file_id":"4999","creator":"system","checksum":"dab6ab36a5f6af94f2b597e6404ed11d","file_size":492310,"content_type":"application/pdf"}],"department":[{"_id":"KrPi"}],"title":"The exact PRF-security of NMAC and HMAC","author":[{"full_name":"Gazi, Peter","last_name":"Gazi","first_name":"Peter","id":"3E0BFE38-F248-11E8-B48F-1D18A9856A87"},{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654"},{"full_name":"Rybar, Michal","last_name":"Rybar","id":"2B3E3DE8-F248-11E8-B48F-1D18A9856A87","first_name":"Michal"}],"issue":"1","day":"01","ddc":["000","004"],"abstract":[{"lang":"eng","text":"NMAC is a mode of operation which turns a fixed input-length keyed hash function f into a variable input-length function. A practical single-key variant of NMAC called HMAC is a very popular and widely deployed message authentication code (MAC). Security proofs and attacks for NMAC can typically be lifted to HMAC. NMAC was introduced by Bellare, Canetti and Krawczyk [Crypto'96], who proved it to be a secure pseudorandom function (PRF), and thus also a MAC, assuming that (1) f is a PRF and (2) the function we get when cascading f is weakly collision-resistant. Unfortunately, HMAC is typically instantiated with cryptographic hash functions like MD5 or SHA-1 for which (2) has been found to be wrong. To restore the provable guarantees for NMAC, Bellare [Crypto'06] showed its security based solely on the assumption that f is a PRF, albeit via a non-uniform reduction. - Our first contribution is a simpler and uniform proof for this fact: If f is an ε-secure PRF (against q queries) and a δ-non-adaptively secure PRF (against q queries), then NMAC f is an (ε+ℓqδ)-secure PRF against q queries of length at most ℓ blocks each. - We then show that this ε+ℓqδ bound is basically tight. For the most interesting case where ℓqδ ≥ ε we prove this by constructing an f for which an attack with advantage ℓqδ exists. This also violates the bound O(ℓε) on the PRF-security of NMAC recently claimed by Koblitz and Menezes. - Finally, we analyze the PRF-security of a modification of NMAC called NI [An and Bellare, Crypto'99] that differs mainly by using a compression function with an additional keying input. This avoids the constant rekeying on multi-block messages in NMAC and allows for a security proof starting by the standard switch from a PRF to a random function, followed by an information-theoretic analysis. We carry out such an analysis, obtaining a tight ℓq2/2 c bound for this step, improving over the trivial bound of ℓ2q2/2c. The proof borrows combinatorial techniques originally developed for proving the security of CBC-MAC [Bellare et al., Crypto'05]."}],"project":[{"_id":"258C570E-B435-11E9-9278-68D0E5697425","name":"Provable Security for Physical Cryptography","call_identifier":"FP7","grant_number":"259668"}],"ec_funded":1,"oa_version":"Submitted Version","alternative_title":["LNCS"],"has_accepted_license":"1","related_material":{"record":[{"id":"838","status":"public","relation":"dissertation_contains"}]},"pubrep_id":"682","corr_author":"1","publication_status":"published","scopus_import":"1"},{"date_created":"2018-12-11T11:55:08Z","language":[{"iso":"eng"}],"quality_controlled":"1","date_published":"2014-06-22T00:00:00Z","month":"06","volume":6,"article_processing_charge":"No","citation":{"short":"K. Mitosch, M.T. Bollenbach, Environmental Microbiology Reports 6 (2014) 545–557.","ista":"Mitosch K, Bollenbach MT. 2014. Bacterial responses to antibiotics and their combinations. Environmental Microbiology Reports. 6(6), 545–557.","chicago":"Mitosch, Karin, and Mark Tobias Bollenbach. “Bacterial Responses to Antibiotics and Their Combinations.” <i>Environmental Microbiology Reports</i>. Wiley, 2014. <a href=\"https://doi.org/10.1111/1758-2229.12190\">https://doi.org/10.1111/1758-2229.12190</a>.","ama":"Mitosch K, Bollenbach MT. Bacterial responses to antibiotics and their combinations. <i>Environmental Microbiology Reports</i>. 2014;6(6):545-557. doi:<a href=\"https://doi.org/10.1111/1758-2229.12190\">10.1111/1758-2229.12190</a>","mla":"Mitosch, Karin, and Mark Tobias Bollenbach. “Bacterial Responses to Antibiotics and Their Combinations.” <i>Environmental Microbiology Reports</i>, vol. 6, no. 6, Wiley, 2014, pp. 545–57, doi:<a href=\"https://doi.org/10.1111/1758-2229.12190\">10.1111/1758-2229.12190</a>.","ieee":"K. Mitosch and M. T. Bollenbach, “Bacterial responses to antibiotics and their combinations,” <i>Environmental Microbiology Reports</i>, vol. 6, no. 6. Wiley, pp. 545–557, 2014.","apa":"Mitosch, K., &#38; Bollenbach, M. T. (2014). Bacterial responses to antibiotics and their combinations. <i>Environmental Microbiology Reports</i>. Wiley. <a href=\"https://doi.org/10.1111/1758-2229.12190\">https://doi.org/10.1111/1758-2229.12190</a>"},"date_updated":"2026-04-08T14:21:56Z","publisher":"Wiley","type":"journal_article","status":"public","intvolume":"         6","doi":"10.1111/1758-2229.12190","publist_id":"5076","_id":"2001","page":"545 - 557","year":"2014","isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","external_id":{"isi":["000345702700002"]},"author":[{"last_name":"Mitosch","full_name":"Mitosch, Karin","id":"39B66846-F248-11E8-B48F-1D18A9856A87","first_name":"Karin"},{"orcid":"0000-0003-4398-476X","full_name":"Bollenbach, Tobias","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","first_name":"Tobias","last_name":"Bollenbach"}],"title":"Bacterial responses to antibiotics and their combinations","department":[{"_id":"ToBo"}],"corr_author":"1","publication_status":"published","scopus_import":"1","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"818"}]},"ec_funded":1,"oa_version":"None","publication":"Environmental Microbiology Reports","issue":"6","abstract":[{"text":"Antibiotics affect bacterial cell physiology at many levels. Rather than just compensating for the direct cellular defects caused by the drug, bacteria respond to antibiotics by changing their morphology, macromolecular composition, metabolism, gene expression and possibly even their mutation rate. Inevitably, these processes affect each other, resulting in a complex response with changes in the expression of numerous genes. Genome‐wide approaches can thus help in gaining a comprehensive understanding of bacterial responses to antibiotics. In addition, a combination of experimental and theoretical approaches is needed for identifying general principles that underlie these responses. Here, we review recent progress in our understanding of bacterial responses to antibiotics and their combinations, focusing on effects at the levels of growth rate and gene expression. We concentrate on studies performed in controlled laboratory conditions, which combine promising experimental techniques with quantitative data analysis and mathematical modeling. While these basic research approaches are not immediately applicable in the clinic, uncovering the principles and mechanisms underlying bacterial responses to antibiotics may, in the long term, contribute to the development of new treatment strategies to cope with and prevent the rise of resistant pathogenic bacteria.","lang":"eng"}],"day":"22","project":[{"_id":"25EB3A80-B435-11E9-9278-68D0E5697425","name":"Revealing the fundamental limits of cell growth","grant_number":"RGP0042/2013"},{"grant_number":"303507","call_identifier":"FP7","name":"Optimality principles in responses to antibiotics","_id":"25E83C2C-B435-11E9-9278-68D0E5697425"}]},{"author":[{"id":"2E3E0988-F248-11E8-B48F-1D18A9856A87","last_name":"Compagnon","full_name":"Compagnon, Julien","first_name":"Julien"},{"orcid":"0000-0003-2676-3367","id":"419EECCC-F248-11E8-B48F-1D18A9856A87","full_name":"Barone, Vanessa","first_name":"Vanessa","last_name":"Barone"},{"full_name":"Rajshekar, Srivarsha","first_name":"Srivarsha","last_name":"Rajshekar"},{"first_name":"Rita","last_name":"Kottmeier","full_name":"Kottmeier, Rita"},{"full_name":"Pranjic-Ferscha, Kornelija","first_name":"Kornelija","id":"4362B3C2-F248-11E8-B48F-1D18A9856A87","last_name":"Pranjic-Ferscha"},{"last_name":"Behrndt","full_name":"Behrndt, Martin","first_name":"Martin","id":"3ECECA3A-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-0912-4566","last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J"}],"external_id":{"pmid":["25535919"],"isi":["000346742900012"]},"department":[{"_id":"CaHe"}],"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pubmed/25535919","open_access":"1"}],"title":"The notochord breaks bilateral symmetry by controlling cell shapes in the Zebrafish laterality organ","related_material":{"record":[{"id":"961","status":"public","relation":"dissertation_contains"}]},"scopus_import":"1","publication_status":"published","corr_author":"1","day":"22","abstract":[{"text":"Kupffer's vesicle (KV) is the zebrafish organ of laterality, patterning the embryo along its left-right (LR) axis. Regional differences in cell shape within the lumen-lining KV epithelium are essential for its LR patterning function. However, the processes by which KV cells acquire their characteristic shapes are largely unknown. Here, we show that the notochord induces regional differences in cell shape within KV by triggering extracellular matrix (ECM) accumulation adjacent to anterior-dorsal (AD) regions of KV. This localized ECM deposition restricts apical expansion of lumen-lining epithelial cells in AD regions of KV during lumen growth. Our study provides mechanistic insight into the processes by which KV translates global embryonic patterning into regional cell shape differences required for its LR symmetry-breaking function.","lang":"eng"}],"issue":"6","publication":"Developmental Cell","oa_version":"Published Version","quality_controlled":"1","language":[{"iso":"eng"}],"date_created":"2018-12-11T11:54:41Z","citation":{"ista":"Compagnon J, Barone V, Rajshekar S, Kottmeier R, Pranjic-Ferscha K, Behrndt M, Heisenberg C-PJ. 2014. The notochord breaks bilateral symmetry by controlling cell shapes in the Zebrafish laterality organ. Developmental Cell. 31(6), 774–783.","short":"J. Compagnon, V. Barone, S. Rajshekar, R. Kottmeier, K. Pranjic-Ferscha, M. Behrndt, C.-P.J. Heisenberg, Developmental Cell 31 (2014) 774–783.","ama":"Compagnon J, Barone V, Rajshekar S, et al. The notochord breaks bilateral symmetry by controlling cell shapes in the Zebrafish laterality organ. <i>Developmental Cell</i>. 2014;31(6):774-783. doi:<a href=\"https://doi.org/10.1016/j.devcel.2014.11.003\">10.1016/j.devcel.2014.11.003</a>","chicago":"Compagnon, Julien, Vanessa Barone, Srivarsha Rajshekar, Rita Kottmeier, Kornelija Pranjic-Ferscha, Martin Behrndt, and Carl-Philipp J Heisenberg. “The Notochord Breaks Bilateral Symmetry by Controlling Cell Shapes in the Zebrafish Laterality Organ.” <i>Developmental Cell</i>. Cell Press, 2014. <a href=\"https://doi.org/10.1016/j.devcel.2014.11.003\">https://doi.org/10.1016/j.devcel.2014.11.003</a>.","apa":"Compagnon, J., Barone, V., Rajshekar, S., Kottmeier, R., Pranjic-Ferscha, K., Behrndt, M., &#38; Heisenberg, C.-P. J. (2014). The notochord breaks bilateral symmetry by controlling cell shapes in the Zebrafish laterality organ. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2014.11.003\">https://doi.org/10.1016/j.devcel.2014.11.003</a>","mla":"Compagnon, Julien, et al. “The Notochord Breaks Bilateral Symmetry by Controlling Cell Shapes in the Zebrafish Laterality Organ.” <i>Developmental Cell</i>, vol. 31, no. 6, Cell Press, 2014, pp. 774–83, doi:<a href=\"https://doi.org/10.1016/j.devcel.2014.11.003\">10.1016/j.devcel.2014.11.003</a>.","ieee":"J. Compagnon <i>et al.</i>, “The notochord breaks bilateral symmetry by controlling cell shapes in the Zebrafish laterality organ,” <i>Developmental Cell</i>, vol. 31, no. 6. Cell Press, pp. 774–783, 2014."},"month":"12","article_processing_charge":"No","volume":31,"oa":1,"date_published":"2014-12-22T00:00:00Z","publist_id":"5182","acknowledgement":"We are grateful to members of the C.-P.H. lab, M. Concha, D. Siekhaus, and J. Vermot for comments on the manuscript and to M. Furutani-Seiki for sharing reagents. This work was supported by the Institute of Science and Technology Austria and an Alexander von Humboldt Foundation fellowship to J.C.","doi":"10.1016/j.devcel.2014.11.003","intvolume":"        31","type":"journal_article","publisher":"Cell Press","status":"public","date_updated":"2026-04-08T14:22:39Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","isi":1,"year":"2014","pmid":1,"page":"774 - 783","_id":"1912"},{"citation":{"ista":"Mabillard I, Wagner U. 2014. Eliminating Tverberg points, I. An analogue of the Whitney trick. Proceedings of the Annual Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, 171–180.","short":"I. Mabillard, U. Wagner, in:, Proceedings of the Annual Symposium on Computational Geometry, ACM, 2014, pp. 171–180.","apa":"Mabillard, I., &#38; Wagner, U. (2014). Eliminating Tverberg points, I. An analogue of the Whitney trick. In <i>Proceedings of the Annual Symposium on Computational Geometry</i> (pp. 171–180). Kyoto, Japan: ACM. <a href=\"https://doi.org/10.1145/2582112.2582134\">https://doi.org/10.1145/2582112.2582134</a>","ieee":"I. Mabillard and U. Wagner, “Eliminating Tverberg points, I. An analogue of the Whitney trick,” in <i>Proceedings of the Annual Symposium on Computational Geometry</i>, Kyoto, Japan, 2014, pp. 171–180.","mla":"Mabillard, Isaac, and Uli Wagner. “Eliminating Tverberg Points, I. An Analogue of the Whitney Trick.” <i>Proceedings of the Annual Symposium on Computational Geometry</i>, ACM, 2014, pp. 171–80, doi:<a href=\"https://doi.org/10.1145/2582112.2582134\">10.1145/2582112.2582134</a>.","ama":"Mabillard I, Wagner U. Eliminating Tverberg points, I. An analogue of the Whitney trick. In: <i>Proceedings of the Annual Symposium on Computational Geometry</i>. ACM; 2014:171-180. doi:<a href=\"https://doi.org/10.1145/2582112.2582134\">10.1145/2582112.2582134</a>","chicago":"Mabillard, Isaac, and Uli Wagner. “Eliminating Tverberg Points, I. An Analogue of the Whitney Trick.” In <i>Proceedings of the Annual Symposium on Computational Geometry</i>, 171–80. ACM, 2014. <a href=\"https://doi.org/10.1145/2582112.2582134\">https://doi.org/10.1145/2582112.2582134</a>."},"oa":1,"month":"06","date_published":"2014-06-08T00:00:00Z","file_date_updated":"2020-07-14T12:45:30Z","quality_controlled":"1","language":[{"iso":"eng"}],"conference":{"name":"SoCG: Symposium on Computational Geometry","end_date":"2014-06-11","location":"Kyoto, Japan","start_date":"2014-06-08"},"date_created":"2018-12-11T11:56:03Z","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","year":"2014","_id":"2159","page":"171 - 180","publist_id":"4847","doi":"10.1145/2582112.2582134","acknowledgement":"Swiss National Science Foundation (Project SNSF-PP00P2-138948)","date_updated":"2026-04-08T14:24:22Z","status":"public","publisher":"ACM","type":"conference","department":[{"_id":"UlWa"}],"file":[{"file_name":"IST-2016-534-v1+1_Eliminating_Tverberg_points_I._An_analogue_of_the_Whitney_trick.pdf","checksum":"2aae223fee8ffeaf57bbabd8d92b6a2c","file_id":"4735","creator":"system","date_created":"2018-12-12T10:09:12Z","access_level":"open_access","relation":"main_file","date_updated":"2020-07-14T12:45:30Z","content_type":"application/pdf","file_size":914396}],"title":"Eliminating Tverberg points, I. An analogue of the Whitney trick","author":[{"full_name":"Mabillard, Isaac","first_name":"Isaac","id":"32BF9DAA-F248-11E8-B48F-1D18A9856A87","last_name":"Mabillard"},{"orcid":"0000-0002-1494-0568","last_name":"Wagner","full_name":"Wagner, Uli","first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"day":"08","ddc":["510"],"abstract":[{"lang":"eng","text":"Motivated by topological Tverberg-type problems, we consider multiple (double, triple, and higher multiplicity) selfintersection points of maps from finite simplicial complexes (compact polyhedra) into ℝd and study conditions under which such multiple points can be eliminated. The most classical case is that of embeddings (i.e., maps without double points) of a κ-dimensional complex K into ℝ2κ. For this problem, the work of van Kampen, Shapiro, and Wu provides an efficiently testable necessary condition for embeddability (namely, vanishing of the van Kampen ob-struction). For κ ≥ 3, the condition is also sufficient, and yields a polynomial-time algorithm for deciding embeddability: One starts with an arbitrary map f : K→ℝ2κ, which generically has finitely many double points; if k ≥ 3 and if the obstruction vanishes then one can successively remove these double points by local modifications of the map f. One of the main tools is the famous Whitney trick that permits eliminating pairs of double points of opposite intersection sign. We are interested in generalizing this approach to intersection points of higher multiplicity. We call a point y 2 ℝd an r-fold Tverberg point of a map f : Kκ →ℝd if y lies in the intersection f(σ1)∩. ∩f(σr) of the images of r pairwise disjoint simplices of K. The analogue of (non-)embeddability that we study is the problem Tverbergκ r→d: Given a κ-dimensional complex K, does it satisfy a Tverberg-type theorem with parameters r and d, i.e., does every map f : K κ → ℝd have an r-fold Tverberg point? Here, we show that for fixed r, κ and d of the form d = rm and k = (r-1)m, m ≥ 3, there is a polynomial-time algorithm for deciding this (based on the vanishing of a cohomological obstruction, as in the case of embeddings). Our main tool is an r-fold analogue of the Whitney trick: Given r pairwise disjoint simplices of K such that the intersection of their images contains two r-fold Tverberg points y+ and y- of opposite intersection sign, we can eliminate y+ and y- by a local isotopy of f. In a subsequent paper, we plan to develop this further and present a generalization of the classical Haeiger-Weber Theorem (which yields a necessary and sufficient condition for embeddability of κ-complexes into ℝd for a wider range of dimensions) to intersection points of higher multiplicity."}],"publication":"Proceedings of the Annual Symposium on Computational Geometry","oa_version":"Submitted Version","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"1123"}]},"has_accepted_license":"1","pubrep_id":"534","scopus_import":1,"corr_author":"1","publication_status":"published"},{"pubrep_id":"297","has_accepted_license":"1","related_material":{"record":[{"id":"1130","status":"public","relation":"dissertation_contains"}]},"alternative_title":["LNCS"],"scopus_import":"1","publication_status":"published","project":[{"grant_number":"267989","name":"Quantitative Reactive Modeling","call_identifier":"FP7","_id":"25EE3708-B435-11E9-9278-68D0E5697425"},{"grant_number":"S11402-N23","name":"Moderne Concurrency Paradigms","call_identifier":"FWF","_id":"25F5A88A-B435-11E9-9278-68D0E5697425"}],"abstract":[{"text":"While fixing concurrency bugs, program repair algorithms may introduce new concurrency bugs. We present an algorithm that avoids such regressions. The solution space is given by a set of program transformations we consider in the repair process. These include reordering of instructions within a thread and inserting atomic sections. The new algorithm learns a constraint on the space of candidate solutions, from both positive examples (error-free traces) and counterexamples (error traces). From each counterexample, the algorithm learns a constraint necessary to remove the errors. From each positive examples, it learns a constraint that is necessary in order to prevent the repair from turning the trace into an error trace. We implemented the algorithm and evaluated it on simplified Linux device drivers with known bugs.","lang":"eng"}],"ddc":["000"],"day":"22","oa_version":"Submitted Version","ec_funded":1,"author":[{"first_name":"Pavol","last_name":"Cerny","full_name":"Cerny, Pavol"},{"last_name":"Henzinger","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","full_name":"Henzinger, Thomas A","orcid":"0000−0002−2985−7724"},{"full_name":"Radhakrishna, Arjun","id":"3B51CAC4-F248-11E8-B48F-1D18A9856A87","first_name":"Arjun","last_name":"Radhakrishna"},{"full_name":"Ryzhyk, Leonid","first_name":"Leonid","last_name":"Ryzhyk"},{"first_name":"Thorsten","last_name":"Tarrach","id":"3D6E8F2C-F248-11E8-B48F-1D18A9856A87","full_name":"Tarrach, Thorsten","orcid":"0000-0003-4409-8487"}],"department":[{"_id":"ToHe"}],"main_file_link":[{"open_access":"1","url":"https://link.springer.com/chapter/10.1007%2F978-3-319-08867-9_38"}],"file":[{"access_level":"open_access","date_updated":"2020-07-14T12:45:33Z","relation":"main_file","date_created":"2018-12-12T10:13:14Z","creator":"system","file_id":"4995","checksum":"a631d3105509f239724644e77a1212e2","file_name":"IST-2014-297-v1+1_cav14-final.pdf","file_size":416732,"content_type":"application/pdf"},{"relation":"main_file","access_level":"open_access","date_updated":"2020-07-14T12:45:33Z","date_created":"2018-12-12T10:13:15Z","file_id":"4996","checksum":"f8b0f748cc9fa697ca992cc56c87bc4e","creator":"system","file_name":"IST-2014-297-v2+1_cav14-final2.pdf","file_size":616293,"content_type":"application/pdf"}],"title":"Regression-free synthesis for concurrency","publist_id":"4749","doi":"10.1007/978-3-319-08867-9_38","intvolume":"      8559","type":"conference","publisher":"Springer","status":"public","date_updated":"2026-04-09T10:54:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2014","page":"568 - 584","_id":"2218","quality_controlled":"1","publication_identifier":{"isbn":["978-331908866-2"]},"language":[{"iso":"eng"}],"conference":{"location":"Vienna, Austria","start_date":"2014-07-18","name":"CAV: Computer Aided Verification","end_date":"2014-07-22"},"date_created":"2018-12-11T11:56:23Z","citation":{"ista":"Cerny P, Henzinger TA, Radhakrishna A, Ryzhyk L, Tarrach T. 2014. Regression-free synthesis for concurrency. CAV: Computer Aided Verification, LNCS, vol. 8559, 568–584.","short":"P. Cerny, T.A. Henzinger, A. Radhakrishna, L. Ryzhyk, T. Tarrach, in:, Springer, 2014, pp. 568–584.","chicago":"Cerny, Pavol, Thomas A Henzinger, Arjun Radhakrishna, Leonid Ryzhyk, and Thorsten Tarrach. “Regression-Free Synthesis for Concurrency,” 8559:568–84. Springer, 2014. <a href=\"https://doi.org/10.1007/978-3-319-08867-9_38\">https://doi.org/10.1007/978-3-319-08867-9_38</a>.","ama":"Cerny P, Henzinger TA, Radhakrishna A, Ryzhyk L, Tarrach T. Regression-free synthesis for concurrency. In: Vol 8559. Springer; 2014:568-584. doi:<a href=\"https://doi.org/10.1007/978-3-319-08867-9_38\">10.1007/978-3-319-08867-9_38</a>","apa":"Cerny, P., Henzinger, T. A., Radhakrishna, A., Ryzhyk, L., &#38; Tarrach, T. (2014). Regression-free synthesis for concurrency (Vol. 8559, pp. 568–584). Presented at the CAV: Computer Aided Verification, Vienna, Austria: Springer. <a href=\"https://doi.org/10.1007/978-3-319-08867-9_38\">https://doi.org/10.1007/978-3-319-08867-9_38</a>","mla":"Cerny, Pavol, et al. <i>Regression-Free Synthesis for Concurrency</i>. Vol. 8559, Springer, 2014, pp. 568–84, doi:<a href=\"https://doi.org/10.1007/978-3-319-08867-9_38\">10.1007/978-3-319-08867-9_38</a>.","ieee":"P. Cerny, T. A. Henzinger, A. Radhakrishna, L. Ryzhyk, and T. Tarrach, “Regression-free synthesis for concurrency,” presented at the CAV: Computer Aided Verification, Vienna, Austria, 2014, vol. 8559, pp. 568–584."},"month":"07","volume":8559,"oa":1,"date_published":"2014-07-22T00:00:00Z","file_date_updated":"2020-07-14T12:45:33Z"},{"file_date_updated":"2020-07-14T12:45:25Z","date_published":"2014-11-27T00:00:00Z","article_processing_charge":"No","volume":4,"month":"11","oa":1,"citation":{"short":"S. Novak, Ecology and Evolution 4 (2014) 4589–4597.","ista":"Novak S. 2014. Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. Ecology and Evolution. 4(24), 4589–4597.","ieee":"S. Novak, “Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution,” <i>Ecology and Evolution</i>, vol. 4, no. 24. Wiley-Blackwell, pp. 4589–4597, 2014.","mla":"Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency Variances as Driving Forces of Dispersal Evolution.” <i>Ecology and Evolution</i>, vol. 4, no. 24, Wiley-Blackwell, 2014, pp. 4589–97, doi:<a href=\"https://doi.org/10.1002/ece3.1289\">10.1002/ece3.1289</a>.","apa":"Novak, S. (2014). Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. <i>Ecology and Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/ece3.1289\">https://doi.org/10.1002/ece3.1289</a>","ama":"Novak S. Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution. <i>Ecology and Evolution</i>. 2014;4(24):4589-4597. doi:<a href=\"https://doi.org/10.1002/ece3.1289\">10.1002/ece3.1289</a>","chicago":"Novak, Sebastian. “Habitat Heterogeneities versus Spatial Type Frequency Variances as Driving Forces of Dispersal Evolution.” <i>Ecology and Evolution</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.1002/ece3.1289\">https://doi.org/10.1002/ece3.1289</a>."},"date_created":"2018-12-11T11:55:16Z","language":[{"iso":"eng"}],"quality_controlled":"1","page":"4589 - 4597","_id":"2023","year":"2014","isi":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publisher":"Wiley-Blackwell","status":"public","date_updated":"2026-04-09T14:25:34Z","intvolume":"         4","doi":"10.1002/ece3.1289","publist_id":"5049","title":"Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution","file":[{"content_type":"application/pdf","file_size":118813,"file_id":"4946","checksum":"9ab43db1b0fede7bfe560ed77e177b76","creator":"system","date_created":"2018-12-12T10:12:28Z","relation":"main_file","date_updated":"2020-07-14T12:45:25Z","access_level":"open_access","file_name":"IST-2016-462-v1+1_Novak-2014-Ecology_and_Evolution.pdf"}],"department":[{"_id":"NiBa"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png"},"external_id":{"isi":["000346736200003"]},"author":[{"orcid":"0000-0002-2519-824X","full_name":"Novak, Sebastian","first_name":"Sebastian","id":"461468AE-F248-11E8-B48F-1D18A9856A87","last_name":"Novak"}],"ec_funded":1,"oa_version":"Published Version","issue":"24","publication":"Ecology and Evolution","project":[{"grant_number":"250152","call_identifier":"FP7","name":"Limits to selection in biology and in evolutionary computation","_id":"25B07788-B435-11E9-9278-68D0E5697425"}],"ddc":["570"],"day":"27","abstract":[{"text":"Understanding the evolution of dispersal is essential for understanding and predicting the dynamics of natural populations. Two main factors are known to influence dispersal evolution: spatio-temporal variation in the environment and relatedness between individuals. However, the relation between these factors is still poorly understood, and they are usually treated separately. In this article, I present a theoretical framework that contains and connects effects of both environmental variation and relatedness, and reproduces and extends their known features. Spatial habitat variation selects for balanced dispersal strategies, whereby the population is kept at an ideal free distribution. Within this class of dispersal strategies, I explain how increased dispersal is promoted by perturbations to the dispersal type frequencies. An explicit formula shows the magnitude of the selective advantage of increased dispersal in terms of the spatial variability in the frequencies of the different dispersal strategies present. These variances are capable of capturing various sources of stochasticity and hence establish a common scale for their effects on the evolution of dispersal. The results furthermore indicate an alternative approach to identifying effects of relatedness on dispersal evolution.","lang":"eng"}],"publication_status":"published","corr_author":"1","scopus_import":"1","pubrep_id":"462","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"1125"}]},"has_accepted_license":"1"},{"degree_awarded":"PhD","publication_identifier":{"issn":["2663-337X"]},"language":[{"iso":"eng"}],"author":[{"last_name":"Konrad","id":"46528076-F248-11E8-B48F-1D18A9856A87","full_name":"Konrad, Matthias","first_name":"Matthias"}],"date_created":"2018-12-11T11:51:46Z","department":[{"_id":"SyCr"}],"citation":{"short":"M. Konrad, Immune Defences in Ants: Effects of Social Immunisation and a Fungal Ectosymbiont in the Ant Lasius Neglectus, Institute of Science and Technology Austria, 2014.","ista":"Konrad M. 2014. Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont in the ant Lasius neglectus. Institute of Science and Technology Austria.","ama":"Konrad M. Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont in the ant Lasius neglectus. 2014.","chicago":"Konrad, Matthias. “Immune Defences in Ants: Effects of Social Immunisation and a Fungal Ectosymbiont in the Ant Lasius Neglectus.” Institute of Science and Technology Austria, 2014.","mla":"Konrad, Matthias. <i>Immune Defences in Ants: Effects of Social Immunisation and a Fungal Ectosymbiont in the Ant Lasius Neglectus</i>. Institute of Science and Technology Austria, 2014.","ieee":"M. Konrad, “Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont in the ant Lasius neglectus,” Institute of Science and Technology Austria, 2014.","apa":"Konrad, M. (2014). <i>Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont in the ant Lasius neglectus</i>. Institute of Science and Technology Austria."},"month":"02","article_processing_charge":"No","date_published":"2014-02-01T00:00:00Z","title":"Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont in the ant Lasius neglectus","publist_id":"5814","OA_place":"publisher","supervisor":[{"orcid":"0000-0002-2193-3868","first_name":"Sylvia M","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","full_name":"Cremer, Sylvia M","last_name":"Cremer"}],"alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","publication_status":"published","status":"public","type":"dissertation","corr_author":"1","date_updated":"2026-04-09T14:27:01Z","day":"01","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","abstract":[{"lang":"eng","text":"In this thesis I studied various individual and social immune defences employed by the invasive garden ant Lasius neglectus mostly against entomopathogenic fungi.  The first two chapters of this thesis address the phenomenon of 'social immunisation'. Social immunisation, that is the immunological protection of group members due to social contact to a pathogen-exposed nestmate, has been described in various social insect species against different types of pathogens. However, in the case of entomopathogenic fungi it has, so far, only been demonstrated that social immunisation exists at all. Its underlying mechanisms r any other properties were, however, unknown. In the first chapter of this thesis I identified the mechanistic basis of social immunisation in L. neglectus against the entomopathogenous fungus Metarhizium. I could show that nestmates of a pathogen-exposed individual contract low-level infections due to social interactions. These low-level infections are, however, non-lethal and cause an active stimulation of the immune system, which protects the nestmates upon subsequent pathogen encounters. In the second chapter of this thesis I investigated the specificity and colony level effects of social immunisation. I demonstrated that the protection conferred by social immunisation is highly specific, protecting ants only against the same pathogen strain. In addition, depending on the respective context, social immunisation may even cause fitness costs. I further showed that social immunisation crucially affects sanitary behaviour and disease dynamics within ant groups. In the third chapter of this thesis I studied the effects of the ectosymbiotic fungus Laboulbenia formicarum on its host L. neglectus. Although Laboulbeniales are the largest order of insect-parasitic fungi, research concerning host fitness consequence is sparse. I showed that highly Laboulbenia-infected ants sustain fitness costs under resource limitation, however, gain fitness benefits when exposed to an entomopathogenus fungus. These effects are probably cause by a prophylactic upregulation of behavioural as well as physiological immune defences in highly infected ants."}],"year":"2014","oa_version":"None","page":"131","_id":"1395"},{"supervisor":[{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří"}],"alternative_title":["ISTA Thesis"],"publist_id":"5805","OA_place":"publisher","type":"dissertation","corr_author":"1","status":"public","publisher":"Institute of Science and Technology Austria","publication_status":"published","date_updated":"2026-04-09T14:27:28Z","abstract":[{"text":"Phosphatidylinositol (Ptdlns) is a structural phospholipid that can be phosphorylated into various lipid signaling molecules, designated polyphosphoinositides (PPIs). The reversible phosphorylation of PPIs on the 3, 4, or 5 position of inositol is performed by a set of organelle-specific kinases and phosphatases, and the characteristic head groups make these molecules ideal for regulating biological processes in time and space. In yeast and mammals, Ptdlns3P and Ptdlns(3,5)P2 play crucial roles in trafficking toward the lytic compartments, whereas the role in plants is not yet fully understood. Here we identified the role of a land plant-specific subgroup of PPI phosphatases, the suppressor of actin 2 (SAC2) to SAC5, during vauolar trafficking and morphogenesis in Arabidopsis thaliana. SAC2-SAC5 localize to the tonoplast along with Ptdlns3P, the presumable product of their activity. in SAC gain- and loss-of-function mutants, the levels of Ptdlns monophosphates and bisphosphates were changed, with opposite effects on the morphology of storage and lytic vacuoles, and the trafficking toward the vacuoles was defective. Moreover, multiple sac knockout mutants had an increased number of smaller storage and lytic vacuoles, whereas extralarge vacuoles were observed in the overexpression lines, correlating with various growth and developmental defects. The fragmented vacuolar phenotype of sac mutants could be mimicked by treating wild-type seedlings with Ptdlns(3,5)P2, corroborating that this PPI is important for vacuole morphology. Taken together, these results provide evidence that PPIs, together with their metabolic enzymes SAC2-SAC5, are crucial for vacuolar trafficking and for vacuolar morphology and function in plants.","lang":"eng"}],"day":"01","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","page":"90","_id":"1402","year":"2014","oa_version":"None","author":[{"first_name":"Petra","full_name":"Marhavá, Petra","id":"44E59624-F248-11E8-B48F-1D18A9856A87","last_name":"Marhavá"}],"language":[{"iso":"eng"}],"degree_awarded":"PhD","publication_identifier":{"issn":["2663-337X"]},"date_created":"2018-12-11T11:51:49Z","month":"12","article_processing_charge":"No","department":[{"_id":"JiFr"}],"citation":{"ieee":"P. Marhavá, “Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis thaliana,” Institute of Science and Technology Austria, 2014.","mla":"Marhavá, Petra. <i>Molecular Mechanisms of Patterning and Subcellular Trafficking in Arabidopsis Thaliana</i>. Institute of Science and Technology Austria, 2014.","apa":"Marhavá, P. (2014). <i>Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis thaliana</i>. Institute of Science and Technology Austria.","chicago":"Marhavá, Petra. “Molecular Mechanisms of Patterning and Subcellular Trafficking in Arabidopsis Thaliana.” Institute of Science and Technology Austria, 2014.","ama":"Marhavá P. Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis thaliana. 2014.","short":"P. Marhavá, Molecular Mechanisms of Patterning and Subcellular Trafficking in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2014.","ista":"Marhavá P. 2014. Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis thaliana. Institute of Science and Technology Austria."},"date_published":"2014-12-01T00:00:00Z","title":"Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis thaliana"}]