[{"article_processing_charge":"Yes (in subscription journal)","isi":1,"license":"https://creativecommons.org/licenses/by/4.0/","month":"07","issue":"7","page":"1243-1255","file_date_updated":"2025-07-22T10:04:57Z","quality_controlled":"1","ddc":["570"],"year":"2025","language":[{"iso":"eng"}],"volume":79,"publication_status":"published","publisher":"Oxford University Press","type":"journal_article","has_accepted_license":"1","PlanS_conform":"1","intvolume":"        79","doi":"10.1093/evolut/qpaf061","citation":{"apa":"Connallon, T., Czuppon, P., Olito, C., Goedert, D., Kokko, H., Nava-Bolaños, A., … Ruzicka, F. (2025). Predicting the prevalence of genetic trade-offs among adaptive substitutions. <i>Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/evolut/qpaf061\">https://doi.org/10.1093/evolut/qpaf061</a>","mla":"Connallon, Tim, et al. “Predicting the Prevalence of Genetic Trade-Offs among Adaptive Substitutions.” <i>Evolution</i>, vol. 79, no. 7, Oxford University Press, 2025, pp. 1243–55, doi:<a href=\"https://doi.org/10.1093/evolut/qpaf061\">10.1093/evolut/qpaf061</a>.","ama":"Connallon T, Czuppon P, Olito C, et al. Predicting the prevalence of genetic trade-offs among adaptive substitutions. <i>Evolution</i>. 2025;79(7):1243-1255. doi:<a href=\"https://doi.org/10.1093/evolut/qpaf061\">10.1093/evolut/qpaf061</a>","short":"T. Connallon, P. Czuppon, C. Olito, D. Goedert, H. Kokko, A. Nava-Bolaños, S. Nilén, E.I. Svensson, M. Zwoinska, L. Dutoit, F. Ruzicka, Evolution 79 (2025) 1243–1255.","ieee":"T. Connallon <i>et al.</i>, “Predicting the prevalence of genetic trade-offs among adaptive substitutions,” <i>Evolution</i>, vol. 79, no. 7. Oxford University Press, pp. 1243–1255, 2025.","ista":"Connallon T, Czuppon P, Olito C, Goedert D, Kokko H, Nava-Bolaños A, Nilén S, Svensson EI, Zwoinska M, Dutoit L, Ruzicka F. 2025. Predicting the prevalence of genetic trade-offs among adaptive substitutions. Evolution. 79(7), 1243–1255.","chicago":"Connallon, Tim, Peter Czuppon, Colin Olito, Debora Goedert, Hanna Kokko, Angela Nava-Bolaños, Sofie Nilén, et al. “Predicting the Prevalence of Genetic Trade-Offs among Adaptive Substitutions.” <i>Evolution</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/evolut/qpaf061\">https://doi.org/10.1093/evolut/qpaf061</a>."},"abstract":[{"lang":"eng","text":"Genetic trade-offs—which occur when variants that are beneficial in some contexts of natural selection are harmful in others—can influence a wide range of evolutionary phenomena, from the maintenance of genetic variation to the evolution of aging and sex differences. An extensive body of evolutionary theory has focused on the consequences of such trade-offs, and recent analyses of Fisher’s geometric model have further quantified the expected proportion of new mutations that exhibit trade-offs. However, the theory remains silent regarding the prevalence of trade-offs among the variants that contribute to adaptation. Here, we extend Fisher’s geometric model to predict the prevalence of trade-offs among the adaptive mutations that become established or fixed in a population. We consider trade-offs between sexes, habitats, fitness components, and temporally fluctuating environments. In all 4 scenarios, trade-off alleles are consistently under-represented among established relative to new beneficial mutations—an effect that arises from the greater susceptibility of trade-off alleles to genetic drift. Adaptation during a population size decline exacerbates this deficit of trade-offs among established mutations, whereas population expansions dampen it. Consequently, threatened populations should primarily adapt using unconditionally beneficial alleles, while invasive populations are more prone to adaptation using variants that exhibit trade-offs."}],"author":[{"full_name":"Connallon, Tim","last_name":"Connallon","first_name":"Tim"},{"first_name":"Peter","last_name":"Czuppon","full_name":"Czuppon, Peter"},{"full_name":"Olito, Colin","last_name":"Olito","first_name":"Colin"},{"first_name":"Debora","last_name":"Goedert","full_name":"Goedert, Debora"},{"full_name":"Kokko, Hanna","first_name":"Hanna","last_name":"Kokko"},{"last_name":"Nava-Bolaños","first_name":"Angela","full_name":"Nava-Bolaños, Angela"},{"full_name":"Nilén, Sofie","first_name":"Sofie","last_name":"Nilén"},{"last_name":"Svensson","first_name":"Erik I","full_name":"Svensson, Erik I"},{"full_name":"Zwoinska, Martyna","first_name":"Martyna","last_name":"Zwoinska"},{"last_name":"Dutoit","first_name":"Ludovic","full_name":"Dutoit, Ludovic"},{"id":"347955dd-57b0-11ee-9095-c28bdd368f4b","full_name":"Ruzicka, Filip","last_name":"Ruzicka","first_name":"Filip"}],"title":"Predicting the prevalence of genetic trade-offs among adaptive substitutions","OA_place":"publisher","article_type":"original","acknowledgement":"Support for this research came from the European Society of Evolutionary Biology (ESEB) through a “Special Topics Network” grant. Further financial support came from the European Research Council (ERC-2023-STG916 #101117517, to C.O.), the Swedish Research Council (#2022-03603, to C.O.; #2020‑03123, to E.I.S.), the Research Council of Norway (Norges forskningsråd #302619, to D.G.), the Alexander von Humboldt Foundation and the GenEvo graduate school (to H.K.), the Foundation for Zoological Research and the Birgitta Sintring Foundation (#S2024-0007, to M.K.Z.), a postdoctoral fellowship from the Consejo Nacional de Humanidades, Ciencias y Tecnología (to A.N.B.), and a H2020 Marie Skłodowska-Curie COFUND Action fellowship (#101034413, to F.R.). We wish to express our deepest gratitude to Lotte de Vries for extensive discussion of the project, rederiving some of our results, and providing comments on an earlier version of the manuscript, and to the European Society of Evolutionary Biology (ESEB) for a “Special Topics Network” grant that supported workshops that initiated this collaboration and facilitated many new ideas and friendships. We also thank two anonymous reviewers for their thoughtful comments and suggestions that helped us to substantially improve upon the original version of the article.","department":[{"_id":"BeVi"}],"day":"01","ec_funded":1,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2025-09-30T14:06:38Z","oa_version":"Published Version","date_created":"2025-07-21T07:57:28Z","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"_id":"20044","publication":"Evolution","file":[{"file_name":"2025_Evolution_Connallon.pdf","creator":"dernst","file_size":8150623,"date_created":"2025-07-22T10:04:57Z","checksum":"68c4c996d0e8c9ee3d4fb61bca75b31a","relation":"main_file","access_level":"open_access","content_type":"application/pdf","success":1,"date_updated":"2025-07-22T10:04:57Z","file_id":"20068"}],"date_published":"2025-07-01T00:00:00Z","publication_identifier":{"eissn":["1558-5646"],"issn":["0014-3820"]},"OA_type":"hybrid","external_id":{"isi":["001477180800001"]},"oa":1},{"status":"public","date_updated":"2025-12-30T07:31:09Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","OA_place":"repository","department":[{"_id":"RoSe"}],"day":"06","author":[{"first_name":"Marco","last_name":"Falconi","full_name":"Falconi, Marco"},{"last_name":"Lampart","first_name":"Jonas","full_name":"Lampart, Jonas"},{"full_name":"Leopold, Nikolai","first_name":"Nikolai","last_name":"Leopold"},{"id":"cbddacee-2b11-11eb-a02e-a2e14d04e52d","last_name":"Mitrouskas","first_name":"David Johannes","full_name":"Mitrouskas, David Johannes"}],"title":"Renormalized Bogoliubov theory for the Nelson model","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2305.06722"}],"external_id":{"arxiv":["2305.06722"]},"oa":1,"date_published":"2025-05-06T00:00:00Z","DOAJ_listed":"1","publication_identifier":{"issn":["0294-1449"],"eissn":["1873-1430"]},"OA_type":"green","arxiv":1,"publication":"Annales de l'Institut Henri Poincaré C","oa_version":"Preprint","date_created":"2025-07-21T07:59:16Z","_id":"20045","language":[{"iso":"eng"}],"quality_controlled":"1","year":"2025","month":"05","article_processing_charge":"No","citation":{"ista":"Falconi M, Lampart J, Leopold N, Mitrouskas DJ. 2025. Renormalized Bogoliubov theory for the Nelson model. Annales de l’Institut Henri Poincaré C.","chicago":"Falconi, Marco, Jonas Lampart, Nikolai Leopold, and David Johannes Mitrouskas. “Renormalized Bogoliubov Theory for the Nelson Model.” <i>Annales de l’Institut Henri Poincaré C</i>. EMS Press, 2025. <a href=\"https://doi.org/10.4171/aihpc/154\">https://doi.org/10.4171/aihpc/154</a>.","ieee":"M. Falconi, J. Lampart, N. Leopold, and D. J. Mitrouskas, “Renormalized Bogoliubov theory for the Nelson model,” <i>Annales de l’Institut Henri Poincaré C</i>. EMS Press, 2025.","ama":"Falconi M, Lampart J, Leopold N, Mitrouskas DJ. Renormalized Bogoliubov theory for the Nelson model. <i>Annales de l’Institut Henri Poincaré C</i>. 2025. doi:<a href=\"https://doi.org/10.4171/aihpc/154\">10.4171/aihpc/154</a>","short":"M. Falconi, J. Lampart, N. Leopold, D.J. Mitrouskas, Annales de l’Institut Henri Poincaré C (2025).","apa":"Falconi, M., Lampart, J., Leopold, N., &#38; Mitrouskas, D. J. (2025). Renormalized Bogoliubov theory for the Nelson model. <i>Annales de l’Institut Henri Poincaré C</i>. EMS Press. <a href=\"https://doi.org/10.4171/aihpc/154\">https://doi.org/10.4171/aihpc/154</a>","mla":"Falconi, Marco, et al. “Renormalized Bogoliubov Theory for the Nelson Model.” <i>Annales de l’Institut Henri Poincaré C</i>, EMS Press, 2025, doi:<a href=\"https://doi.org/10.4171/aihpc/154\">10.4171/aihpc/154</a>."},"abstract":[{"lang":"eng","text":"We consider the time evolution of the renormalized Nelson model, which describes N bosons linearly coupled to a quantized scalar field, in the mean-field limit of many particles N≫1 with coupling constant proportional to N^−1/2. First, we show that initial states exhibiting Bose–Einstein condensation for the particles and approximating a coherent state for the quantum field retain their structure under the many-body time evolution. Concretely, the dynamics of the reduced densities are approximated by solutions of two coupled PDEs, the Schrödinger–Klein–Gordon equations. Second, we construct a renormalized Bogoliubov evolution that describes the quantum fluctuations around the Schrödinger–Klein–Gordon equations. This evolution is used to extend the approximation of the evolved many-body state to the full norm topology. In summary, we provide a comprehensive analysis of the Nelson model that reveals the role of renormalization in the mean-field Bogoliubov theory."}],"doi":"10.4171/aihpc/154","publication_status":"epub_ahead","type":"journal_article","publisher":"EMS Press"},{"_id":"20046","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","grant_number":"101020331","call_identifier":"H2020","name":"Random matrices beyond Wigner-Dyson-Mehta"}],"date_created":"2025-07-21T08:06:18Z","oa_version":"Published Version","file":[{"relation":"main_file","file_size":580591,"checksum":"a7a9f2bb7a6295786c16d4c7bd612621","date_created":"2025-07-23T08:35:53Z","creator":"dernst","file_name":"2025_ElectronJourProbab_Campbell.pdf","file_id":"20069","content_type":"application/pdf","success":1,"date_updated":"2025-07-23T08:35:53Z","access_level":"open_access"}],"publication":"Electronic Journal of Probability","arxiv":1,"publication_identifier":{"eissn":["1083-6489"]},"OA_type":"gold","DOAJ_listed":"1","date_published":"2025-06-27T00:00:00Z","oa":1,"external_id":{"arxiv":["2211.17175"],"isi":["001540927000024"]},"author":[{"id":"582b06a9-1f1c-11ee-b076-82ffce00dde4","full_name":"Campbell, Andrew J","first_name":"Andrew J","last_name":"Campbell"},{"first_name":"Kyle","last_name":"Luh","full_name":"Luh, Kyle"},{"full_name":"O’Rourke, Sean","last_name":"O’Rourke","first_name":"Sean"},{"full_name":"Arenas-Velilla, Santiago","first_name":"Santiago","last_name":"Arenas-Velilla"},{"last_name":"Perez-Abreu","first_name":"Victor","full_name":"Perez-Abreu, Victor"}],"title":"Extreme eigenvalues of Laplacian random matrices with Gaussian entries","ec_funded":1,"department":[{"_id":"LaEr"}],"day":"27","acknowledgement":"The authors thank Santiago Arenas-Velilla and Victor Pérez-Abreu for comments on an earlier draft of this manuscript and for contributing Appendix A. The authors also thank Yan Fyodorov for providing useful references.\r\nA. Campbell was partially supported by the European Research Council Grant No. 101020331. K. Luh was supported in part by the Ralph E. Powe Junior Faculty Enhancement Award and Simons Foundation Grant MP-TSM-00001988. S. O’Rourke has been supported in part by NSF CAREER grant DMS-2143142. ","article_type":"original","OA_place":"publisher","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_updated":"2025-09-30T14:07:19Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","corr_author":"1","type":"journal_article","publisher":"Institute of Mathematical Statistics","publication_status":"published","intvolume":"        30","has_accepted_license":"1","doi":"10.1214/25-ejp1366","abstract":[{"text":"A Laplacian matrix is a real symmetric matrix whose row and column sums are zero. We investigate the limiting distribution of the largest eigenvalues of a Laplacian random matrix with Gaussian entries. Unlike many classical matrix ensembles, this random matrix model contains dependent entries. Our main results show that the extreme eigenvalues of this model exhibit Poisson statistics. In particular, after properly shifting and scaling, we show that the largest eigenvalue converges to the Gumbel distribution as the dimension of the matrix tends to infinity. While the largest diagonal entry is also shown to have Gumbel fluctuations, there is a rather surprising difference between its deterministic centering term and the centering term required for the largest eigenvalues.","lang":"eng"}],"citation":{"chicago":"Campbell, Andrew J, Kyle Luh, Sean O’Rourke, Santiago Arenas-Velilla, and Victor Perez-Abreu. “Extreme Eigenvalues of Laplacian Random Matrices with Gaussian Entries.” <i>Electronic Journal of Probability</i>. Institute of Mathematical Statistics, 2025. <a href=\"https://doi.org/10.1214/25-ejp1366\">https://doi.org/10.1214/25-ejp1366</a>.","ista":"Campbell AJ, Luh K, O’Rourke S, Arenas-Velilla S, Perez-Abreu V. 2025. Extreme eigenvalues of Laplacian random matrices with Gaussian entries. Electronic Journal of Probability. 30, 1–52.","ieee":"A. J. Campbell, K. Luh, S. O’Rourke, S. Arenas-Velilla, and V. Perez-Abreu, “Extreme eigenvalues of Laplacian random matrices with Gaussian entries,” <i>Electronic Journal of Probability</i>, vol. 30. Institute of Mathematical Statistics, pp. 1–52, 2025.","short":"A.J. Campbell, K. Luh, S. O’Rourke, S. Arenas-Velilla, V. Perez-Abreu, Electronic Journal of Probability 30 (2025) 1–52.","ama":"Campbell AJ, Luh K, O’Rourke S, Arenas-Velilla S, Perez-Abreu V. Extreme eigenvalues of Laplacian random matrices with Gaussian entries. <i>Electronic Journal of Probability</i>. 2025;30:1-52. doi:<a href=\"https://doi.org/10.1214/25-ejp1366\">10.1214/25-ejp1366</a>","mla":"Campbell, Andrew J., et al. “Extreme Eigenvalues of Laplacian Random Matrices with Gaussian Entries.” <i>Electronic Journal of Probability</i>, vol. 30, Institute of Mathematical Statistics, 2025, pp. 1–52, doi:<a href=\"https://doi.org/10.1214/25-ejp1366\">10.1214/25-ejp1366</a>.","apa":"Campbell, A. J., Luh, K., O’Rourke, S., Arenas-Velilla, S., &#38; Perez-Abreu, V. (2025). Extreme eigenvalues of Laplacian random matrices with Gaussian entries. <i>Electronic Journal of Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/25-ejp1366\">https://doi.org/10.1214/25-ejp1366</a>"},"isi":1,"article_processing_charge":"Yes","file_date_updated":"2025-07-23T08:35:53Z","page":"1-52","month":"06","year":"2025","ddc":["510"],"quality_controlled":"1","volume":30,"language":[{"iso":"eng"}]},{"volume":35,"language":[{"iso":"eng"}],"year":"2025","quality_controlled":"1","page":"1913-1940","issue":"3","month":"06","isi":1,"article_processing_charge":"No","abstract":[{"text":"We prove upper bounds on the L∞-Wasserstein distance from optimal transport between strongly log-concave probability densities and log-Lipschitz perturbations. In the simplest setting, such a bound amounts to a transport-information inequality involving the L∞-Wasserstein metric and the relative L∞-Fisher information. We show that this inequality can be sharpened significantly in situations where the involved densities are anisotropic. Our proof is based on probabilistic techniques using Langevin dynamics. As an application of these results, we obtain sharp exponential rates of convergence in Fisher’s infinitesimal model from quantitative genetics, generalising recent results by Calvez, Poyato, and Santambrogio in dimension 1 to arbitrary dimensions.","lang":"eng"}],"citation":{"mla":"Khudiakova, Kseniia, et al. “L∞-Optimal Transport of Anisotropic Log-Concave Measures and Exponential Convergence in Fisher’s Infinitesimal Model.” <i>The Annals of Applied Probability</i>, vol. 35, no. 3, Institute of Mathematical Statistics, 2025, pp. 1913–40, doi:<a href=\"https://doi.org/10.1214/25-aap2162\">10.1214/25-aap2162</a>.","apa":"Khudiakova, K., Maas, J., &#38; Pedrotti, F. (2025). L∞-optimal transport of anisotropic log-concave measures and exponential convergence in Fisher’s infinitesimal model. <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/25-aap2162\">https://doi.org/10.1214/25-aap2162</a>","ieee":"K. Khudiakova, J. Maas, and F. Pedrotti, “L∞-optimal transport of anisotropic log-concave measures and exponential convergence in Fisher’s infinitesimal model,” <i>The Annals of Applied Probability</i>, vol. 35, no. 3. Institute of Mathematical Statistics, pp. 1913–1940, 2025.","ista":"Khudiakova K, Maas J, Pedrotti F. 2025. L∞-optimal transport of anisotropic log-concave measures and exponential convergence in Fisher’s infinitesimal model. The Annals of Applied Probability. 35(3), 1913–1940.","chicago":"Khudiakova, Kseniia, Jan Maas, and Francesco Pedrotti. “L∞-Optimal Transport of Anisotropic Log-Concave Measures and Exponential Convergence in Fisher’s Infinitesimal Model.” <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics, 2025. <a href=\"https://doi.org/10.1214/25-aap2162\">https://doi.org/10.1214/25-aap2162</a>.","ama":"Khudiakova K, Maas J, Pedrotti F. L∞-optimal transport of anisotropic log-concave measures and exponential convergence in Fisher’s infinitesimal model. <i>The Annals of Applied Probability</i>. 2025;35(3):1913-1940. doi:<a href=\"https://doi.org/10.1214/25-aap2162\">10.1214/25-aap2162</a>","short":"K. Khudiakova, J. Maas, F. Pedrotti, The Annals of Applied Probability 35 (2025) 1913–1940."},"related_material":{"record":[{"status":"public","id":"17352","relation":"earlier_version"}]},"doi":"10.1214/25-aap2162","scopus_import":"1","intvolume":"        35","corr_author":"1","type":"journal_article","publisher":"Institute of Mathematical Statistics","publication_status":"published","date_updated":"2025-09-30T14:12:48Z","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","day":"01","department":[{"_id":"JaMa"}],"OA_place":"repository","article_type":"original","acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF) project 10.55776/F65 and the Austrian Academy of Science, DOC fellowship nr. 26293.","author":[{"full_name":"Khudiakova, Kseniia","orcid":"0000-0002-6246-1465","last_name":"Khudiakova","first_name":"Kseniia","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425"},{"id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan","orcid":"0000-0002-0845-1338","last_name":"Maas","first_name":"Jan"},{"id":"d3ac8ac6-dc8d-11ea-abe3-e2a9628c4c3c","first_name":"Francesco","last_name":"Pedrotti","full_name":"Pedrotti, Francesco"}],"title":"L∞-optimal transport of anisotropic log-concave measures and exponential convergence in Fisher’s infinitesimal model","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2402.04151"}],"external_id":{"isi":["001523520000012"],"arxiv":["2402.04151"]},"oa":1,"publication_identifier":{"issn":["1050-5164"]},"OA_type":"green","arxiv":1,"date_published":"2025-06-01T00:00:00Z","publication":"The Annals of Applied Probability","project":[{"grant_number":"F6504","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems"},{"name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8","grant_number":"26293"}],"_id":"20050","oa_version":"Preprint","date_created":"2025-07-21T08:13:54Z"},{"external_id":{"isi":["001525534800069"]},"oa":1,"date_published":"2025-06-13T00:00:00Z","OA_type":"hybrid","publication_identifier":{"isbn":["9798400718854"]},"publication":"Proceedings of the ACM Symposium on Principles of Distributed Computing","file":[{"date_updated":"2025-08-05T07:32:01Z","content_type":"application/pdf","success":1,"access_level":"open_access","file_id":"20123","creator":"dernst","file_name":"2025_PODC_Breitkopf.pdf","relation":"main_file","checksum":"e99679ffb28877b7cea4d54860302790","date_created":"2025-08-05T07:32:01Z","file_size":549706}],"oa_version":"Published Version","date_created":"2025-07-21T08:17:04Z","project":[{"name":"The design and evaluation of modern fully dynamic data structures","call_identifier":"H2020","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62","grant_number":"101019564"},{"name":"Static and Dynamic Hierarchical Graph Decompositions","_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","grant_number":"I05982"},{"name":"Fast Algorithms for a Reactive Network Layer","_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","grant_number":"P33775"}],"_id":"20052","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2026-02-16T11:46:37Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (MoDynStruct, No. 101019564) and the Austrian Science Fund (FWF) grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775 with additional funding from the netidee SCIENCE Stiftung, 2020–2024 and the German Research Foundation (DFG), grant 470029389 (FlexNets). ","department":[{"_id":"MoHe"}],"day":"13","ec_funded":1,"title":"Brief announcement: Minimizing energy solves relative majority with a cubic number of states in population protocols","author":[{"last_name":"Breitkopf","first_name":"Tom-Lukas","full_name":"Breitkopf, Tom-Lukas"},{"last_name":"Dallot","first_name":"Julien","full_name":"Dallot, Julien"},{"id":"888a098e-fcac-11ee-aff7-d347be57b725","full_name":"El-Hayek, Antoine","orcid":"0000-0003-4268-7368","first_name":"Antoine","last_name":"El-Hayek"},{"first_name":"Stefan","last_name":"Schmid","full_name":"Schmid, Stefan"}],"citation":{"mla":"Breitkopf, Tom-Lukas, et al. “Brief Announcement: Minimizing Energy Solves Relative Majority with a Cubic Number of States in Population Protocols.” <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2025, pp. 549–52, doi:<a href=\"https://doi.org/10.1145/3732772.3733512\">10.1145/3732772.3733512</a>.","apa":"Breitkopf, T.-L., Dallot, J., El-Hayek, A., &#38; Schmid, S. (2025). Brief announcement: Minimizing energy solves relative majority with a cubic number of states in population protocols. In <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i> (pp. 549–552). Huatulco, Mexico: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3732772.3733512\">https://doi.org/10.1145/3732772.3733512</a>","ama":"Breitkopf T-L, Dallot J, El-Hayek A, Schmid S. Brief announcement: Minimizing energy solves relative majority with a cubic number of states in population protocols. In: <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2025:549-552. doi:<a href=\"https://doi.org/10.1145/3732772.3733512\">10.1145/3732772.3733512</a>","short":"T.-L. Breitkopf, J. Dallot, A. El-Hayek, S. Schmid, in:, Proceedings of the ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2025, pp. 549–552.","ieee":"T.-L. Breitkopf, J. Dallot, A. El-Hayek, and S. Schmid, “Brief announcement: Minimizing energy solves relative majority with a cubic number of states in population protocols,” in <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, Huatulco, Mexico, 2025, pp. 549–552.","chicago":"Breitkopf, Tom-Lukas, Julien Dallot, Antoine El-Hayek, and Stefan Schmid. “Brief Announcement: Minimizing Energy Solves Relative Majority with a Cubic Number of States in Population Protocols.” In <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, 549–52. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3732772.3733512\">https://doi.org/10.1145/3732772.3733512</a>.","ista":"Breitkopf T-L, Dallot J, El-Hayek A, Schmid S. 2025. Brief announcement: Minimizing energy solves relative majority with a cubic number of states in population protocols. Proceedings of the ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 549–552."},"abstract":[{"lang":"eng","text":"This paper revisits a fundamental distributed computing problem in the population protocol model. Provided n agents each starting with an input color in [k], the relative majority problem asks to find the predominant color. In the population protocol model, at each time step, a scheduler selects two agents that first learn each other's states and then update their states based on what they learned.\r\nWe present the Circles protocol that solves the relative majority problem with k3 states. It is always-correct under weakly fair scheduling. Not only does it improve upon the best known upper bound of O(k7), but it also shows a strikingly simpler design inspired by energy minimization in chemical settings."}],"doi":"10.1145/3732772.3733512","has_accepted_license":"1","publication_status":"published","publisher":"Association for Computing Machinery","corr_author":"1","type":"conference","language":[{"iso":"eng"}],"quality_controlled":"1","ddc":["000"],"year":"2025","conference":{"location":"Huatulco, Mexico","name":"PODC: Symposium on Principles of Distributed Computing","end_date":"2025-06-20","start_date":"2025-06-16"},"month":"06","page":"549-552","file_date_updated":"2025-08-05T07:32:01Z","article_processing_charge":"No","isi":1},{"language":[{"iso":"eng"}],"ddc":["000"],"conference":{"start_date":"2025-06-16","location":"Huatulco, Mexico","name":"PODC: Symposium on Principles of Distributed Computing","end_date":"2025-06-20"},"year":"2025","quality_controlled":"1","page":"241-251","file_date_updated":"2025-08-05T07:15:31Z","month":"06","isi":1,"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Liquid democracy is a transitive vote delegation mechanism over voting graphs. It enables each voter to delegate their vote(s) to another better-informed voter, with the goal of collectively making a better decision. The question of whether liquid democracy outperforms direct voting has been previously studied in the context of local delegation mechanisms (where voters can only delegate to someone in their neighbourhood) and binary decision problems. It has previously been shown that it is impossible for local delegation mechanisms to outperform direct voting in general graphs. This raises the question: for which classes of graphs do local delegation mechanisms yield good results?\r\nIn this work, we analyse (1) properties of specific graphs and (2) properties of local delegation mechanisms on these graphs, determining where local delegation actually outperforms direct voting. We show that a critical graph property enabling liquid democracy is that the voting outcome of local delegation mechanisms preserves a sufficient amount of variance, thereby avoiding situations where delegation falls behind direct voting1. These insights allow us to prove our main results, namely that there exist local delegation mechanisms that perform no worse and in fact quantitatively better than direct voting in natural graph topologies like complete, random d-regular, and bounded degree graphs, lending a more nuanced perspective to previous impossibility results."}],"citation":{"ista":"Chatterjee K, Gilbert S, Schmid S, Svoboda J, Yeo MX. 2025. When is liquid democracy possible?: On the manipulation of variance. Proceedings of the ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 241–251.","chicago":"Chatterjee, Krishnendu, Seth Gilbert, Stefan Schmid, Jakub Svoboda, and Michelle X Yeo. “When Is Liquid Democracy Possible?: On the Manipulation of Variance.” In <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, 241–51. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3732772.3733544\">https://doi.org/10.1145/3732772.3733544</a>.","ieee":"K. Chatterjee, S. Gilbert, S. Schmid, J. Svoboda, and M. X. Yeo, “When is liquid democracy possible?: On the manipulation of variance,” in <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, Huatulco, Mexico, 2025, pp. 241–251.","short":"K. Chatterjee, S. Gilbert, S. Schmid, J. Svoboda, M.X. Yeo, in:, Proceedings of the ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2025, pp. 241–251.","ama":"Chatterjee K, Gilbert S, Schmid S, Svoboda J, Yeo MX. When is liquid democracy possible?: On the manipulation of variance. In: <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2025:241-251. doi:<a href=\"https://doi.org/10.1145/3732772.3733544\">10.1145/3732772.3733544</a>","mla":"Chatterjee, Krishnendu, et al. “When Is Liquid Democracy Possible?: On the Manipulation of Variance.” <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2025, pp. 241–51, doi:<a href=\"https://doi.org/10.1145/3732772.3733544\">10.1145/3732772.3733544</a>.","apa":"Chatterjee, K., Gilbert, S., Schmid, S., Svoboda, J., &#38; Yeo, M. X. (2025). When is liquid democracy possible?: On the manipulation of variance. In <i>Proceedings of the ACM Symposium on Principles of Distributed Computing</i> (pp. 241–251). Huatulco, Mexico: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3732772.3733544\">https://doi.org/10.1145/3732772.3733544</a>"},"doi":"10.1145/3732772.3733544","has_accepted_license":"1","type":"conference","publisher":"Association for Computing Machinery","corr_author":"1","publication_status":"published","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2026-02-16T11:46:51Z","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"KrCh"},{"_id":"KrPi"}],"day":"13","ec_funded":1,"OA_place":"publisher","acknowledgement":"This work was partially supported by MOE-T2EP20122-0014 (DataDriven Distributed Algorithms), German Research Foundation (DFG) project ReNO (SPP 2378) from 2023-2027, ERC CoG 863818 (ForMSMArt) and Austrian Science Fund (FWF) 10.55776/COE12.","author":[{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu","last_name":"Chatterjee","full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X"},{"full_name":"Gilbert, Seth","first_name":"Seth","last_name":"Gilbert"},{"full_name":"Schmid, Stefan","first_name":"Stefan","last_name":"Schmid"},{"id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","full_name":"Svoboda, Jakub","orcid":"0000-0002-1419-3267","first_name":"Jakub","last_name":"Svoboda"},{"orcid":"0009-0001-3676-4809","full_name":"Yeo, Michelle X","last_name":"Yeo","first_name":"Michelle X","id":"2D82B818-F248-11E8-B48F-1D18A9856A87"}],"main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/745"}],"title":"When is liquid democracy possible?: On the manipulation of variance","external_id":{"isi":["001525534800030"]},"oa":1,"publication_identifier":{"isbn":["9798400718854"]},"OA_type":"hybrid","date_published":"2025-06-13T00:00:00Z","file":[{"file_name":"2025_PODC_Chatterjee.pdf","creator":"dernst","file_size":783297,"date_created":"2025-08-05T07:15:31Z","checksum":"cd628fe54d96e9fc6cc789bb8145422b","relation":"main_file","access_level":"open_access","content_type":"application/pdf","success":1,"date_updated":"2025-08-05T07:15:31Z","file_id":"20122"}],"publication":"Proceedings of the ACM Symposium on Principles of Distributed Computing","project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","grant_number":"863818","call_identifier":"H2020","name":"Formal Methods for Stochastic Models: Algorithms and Applications"}],"_id":"20053","oa_version":"Published Version","date_created":"2025-07-21T08:18:26Z"},{"conference":{"start_date":"2025-03-03","end_date":"2025-03-07","name":"MATSUS: Materials for Sustainable Development Conference","location":"Sevilla, Spain"},"year":"2025","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NMR"},{"_id":"LifeSc"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","date_updated":"2026-02-19T09:25:57Z","status":"public","language":[{"iso":"eng"}],"title":"Reaction precursor-mediated formation of stable supercrystals in colloidal nanocrystal synthesis: PbTe case","author":[{"last_name":"Lee","first_name":"Seungho","full_name":"Lee, Seungho","orcid":"0000-0002-6962-8598","id":"BB243B88-D767-11E9-B658-BC13E6697425"},{"id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","orcid":"0000-0001-7597-043X","full_name":"Balazs, Daniel","first_name":"Daniel","last_name":"Balazs"},{"full_name":"Horta, Sharona","first_name":"Sharona","last_name":"Horta","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc"},{"id":"8aceb01b-8972-11ed-ae7b-d5fe53775add","full_name":"Rayaroth Puthiyaveettil, Aiswarya","first_name":"Aiswarya","last_name":"Rayaroth Puthiyaveettil"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","first_name":"Maria","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843"}],"article_processing_charge":"No","department":[{"_id":"MaIb"},{"_id":"LifeSc"}],"day":"15","acknowledgement":"ISTA and the Werner Siemens Foundation financially supported this work. The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF), NMR Facility and the Lab Support Facility (LSF).","month":"03","doi":"10.29363/nanoge.matsusspring.2025.173","OA_type":"closed access","date_published":"2025-03-15T00:00:00Z","abstract":[{"text":"Supercrystals represent three-dimensional orderings of colloidal nanocrystals (NCs), showcasing collective properties in photonics, phononics, and electronics applications.1,2 Recent studies have shown that such assemblies are directly produced during nanocrystal reactions.3–6 However, a fundamental understanding of in situ formed supercrystals that withstand typical NC purification processes remains underexplored, which is important for further use. Herein, we report the reaction precursor-mediated formation of stable PbTe supercrystals. Rationalizing the formation of these assemblies through small-angle x-ray scattering (SAXS) measurements, we unveil their formation mechanism. Our findings reveal that the supercrystal formation occurs in the presence of an excess of lead oleates in the crude solution. It should be noted that the formed supercrystals can be stabilized under specific conditions determined by the lead oleate cluster concentration, content of trioctylphosphine telluride (TOP-Te), NC size and the need of an annealing step at mild conditions. Furthermore, this approach allows for the continuous growth of a secondary phase within the supercrystal; for example in the case of PbTe supercrystals, a PbS shell can be grown on each PbTe NC constituent, resulting in core-shell PbTe-PbS supercrystals. Our work elucidates that reaction precursors play an important role in in situ SC formation and stabilization, implying the possibility of applying this knowledge to other NC reactions.","lang":"eng"}],"citation":{"short":"S. Lee, D. Balazs, S. Horta, A. Rayaroth Puthiyaveettil, M. Ibáñez, in:, Proceedings of the MATSUS Spring 2025 Conference, Fundació de la comunitat valenciana SCITO, 2025.","ama":"Lee S, Balazs D, Horta S, Rayaroth Puthiyaveettil A, Ibáñez M. Reaction precursor-mediated formation of stable supercrystals in colloidal nanocrystal synthesis: PbTe case. In: <i>Proceedings of the MATSUS Spring 2025 Conference</i>. Fundació de la comunitat valenciana SCITO; 2025. doi:<a href=\"https://doi.org/10.29363/nanoge.matsusspring.2025.173\">10.29363/nanoge.matsusspring.2025.173</a>","ieee":"S. Lee, D. Balazs, S. Horta, A. Rayaroth Puthiyaveettil, and M. Ibáñez, “Reaction precursor-mediated formation of stable supercrystals in colloidal nanocrystal synthesis: PbTe case,” in <i>Proceedings of the MATSUS Spring 2025 Conference</i>, Sevilla, Spain, 2025.","ista":"Lee S, Balazs D, Horta S, Rayaroth Puthiyaveettil A, Ibáñez M. 2025. Reaction precursor-mediated formation of stable supercrystals in colloidal nanocrystal synthesis: PbTe case. Proceedings of the MATSUS Spring 2025 Conference. MATSUS: Materials for Sustainable Development Conference, 173.","chicago":"Lee, Seungho, Daniel Balazs, Sharona Horta, Aiswarya Rayaroth Puthiyaveettil, and Maria Ibáñez. “Reaction Precursor-Mediated Formation of Stable Supercrystals in Colloidal Nanocrystal Synthesis: PbTe Case.” In <i>Proceedings of the MATSUS Spring 2025 Conference</i>. Fundació de la comunitat valenciana SCITO, 2025. <a href=\"https://doi.org/10.29363/nanoge.matsusspring.2025.173\">https://doi.org/10.29363/nanoge.matsusspring.2025.173</a>.","mla":"Lee, Seungho, et al. “Reaction Precursor-Mediated Formation of Stable Supercrystals in Colloidal Nanocrystal Synthesis: PbTe Case.” <i>Proceedings of the MATSUS Spring 2025 Conference</i>, 173, Fundació de la comunitat valenciana SCITO, 2025, doi:<a href=\"https://doi.org/10.29363/nanoge.matsusspring.2025.173\">10.29363/nanoge.matsusspring.2025.173</a>.","apa":"Lee, S., Balazs, D., Horta, S., Rayaroth Puthiyaveettil, A., &#38; Ibáñez, M. (2025). Reaction precursor-mediated formation of stable supercrystals in colloidal nanocrystal synthesis: PbTe case. In <i>Proceedings of the MATSUS Spring 2025 Conference</i>. Sevilla, Spain: Fundació de la comunitat valenciana SCITO. <a href=\"https://doi.org/10.29363/nanoge.matsusspring.2025.173\">https://doi.org/10.29363/nanoge.matsusspring.2025.173</a>"},"corr_author":"1","_id":"20055","publisher":"Fundació de la comunitat valenciana SCITO","type":"conference","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"date_created":"2025-07-21T08:33:20Z","article_number":"173","oa_version":"None","publication_status":"published","publication":"Proceedings of the MATSUS Spring 2025 Conference"},{"oa":1,"external_id":{"arxiv":["2205.02645"],"isi":["001433250500001"],"pmid":["40179429"]},"date_published":"2025-04-01T00:00:00Z","arxiv":1,"publication_identifier":{"issn":["0003-0147"],"eissn":["1537-5323"]},"OA_type":"green","publication":"The American Naturalist","date_created":"2025-07-21T08:37:27Z","oa_version":"Preprint","_id":"20056","pmid":1,"project":[{"grant_number":"ALTF 343-2022","_id":"34e2a5b5-11ca-11ed-8bc3-b2265616ef0b","name":"A mechano-chemical theory for stem cell fate decisions in organoid development"}],"status":"public","date_updated":"2025-09-30T14:14:43Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"V.G. acknowledges support from the Science and Engi-neering Research Board, Department of Biotechnology,and the Indo-French Centre for the Promotion of Ad-vanced Research (64T4-1). D.R.M. acknowledges supportfrom a Department of Science and Technology (DST) In-novation in Science Pursuit for Inspired Research (IN-SPIRE) Faculty Award. J.J. acknowledges support froma Humboldt postdoctoral fellowship and the Heidelber-ger Akademie der Wissenschaften, Heidelberg, Germany.D.B.B. acknowledges support from the NOMIS Founda-tion and an European Molecular Biology Organization(EMBO) postdoctoral fellowship (ALTF 343-2022). A.N.and S.P. acknowledge support from Ministry of Educa-tion (MoE) PhD fellowships. We thank Ashrit Mangal-wedhekar, Vivek Jadhav, Shikhara Bhat, Cassandre Aimon,and Harishankar Muppirala for comments on the manu-script and code. We thank Kollegala Sharma for his inputon the Kannada translation of the title and abstract.Data-Driven Model Discovery E115","article_type":"original","OA_place":"repository","department":[{"_id":"EdHa"}],"day":"01","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2205.02645","open_access":"1"}],"title":"Discovering stochastic dynamical equations from ecological time series data","author":[{"full_name":"Nabeel, Arshed","first_name":"Arshed","last_name":"Nabeel"},{"last_name":"Karichannavar","first_name":"Ashwin","full_name":"Karichannavar, Ashwin"},{"full_name":"Palathingal, Shuaib","last_name":"Palathingal","first_name":"Shuaib"},{"last_name":"Jhawar","first_name":"Jitesh","full_name":"Jhawar, Jitesh"},{"id":"e1e86031-6537-11eb-953a-f7ab92be508d","first_name":"David","last_name":"Brückner","full_name":"Brückner, David","orcid":"0000-0001-7205-2975"},{"full_name":"Raj M, Danny","last_name":"Raj M","first_name":"Danny"},{"full_name":"Guttal, Vishwesha","last_name":"Guttal","first_name":"Vishwesha"}],"citation":{"ieee":"A. Nabeel <i>et al.</i>, “Discovering stochastic dynamical equations from ecological time series data,” <i>The American Naturalist</i>, vol. 205, no. 4. University of Chicago Press, pp. E100–E117, 2025.","ista":"Nabeel A, Karichannavar A, Palathingal S, Jhawar J, Brückner D, Raj M D, Guttal V. 2025. Discovering stochastic dynamical equations from ecological time series data. The American Naturalist. 205(4), E100–E117.","chicago":"Nabeel, Arshed, Ashwin Karichannavar, Shuaib Palathingal, Jitesh Jhawar, David Brückner, Danny Raj M, and Vishwesha Guttal. “Discovering Stochastic Dynamical Equations from Ecological Time Series Data.” <i>The American Naturalist</i>. University of Chicago Press, 2025. <a href=\"https://doi.org/10.1086/734083\">https://doi.org/10.1086/734083</a>.","short":"A. Nabeel, A. Karichannavar, S. Palathingal, J. Jhawar, D. Brückner, D. Raj M, V. Guttal, The American Naturalist 205 (2025) E100–E117.","ama":"Nabeel A, Karichannavar A, Palathingal S, et al. Discovering stochastic dynamical equations from ecological time series data. <i>The American Naturalist</i>. 2025;205(4):E100-E117. doi:<a href=\"https://doi.org/10.1086/734083\">10.1086/734083</a>","mla":"Nabeel, Arshed, et al. “Discovering Stochastic Dynamical Equations from Ecological Time Series Data.” <i>The American Naturalist</i>, vol. 205, no. 4, University of Chicago Press, 2025, pp. E100–17, doi:<a href=\"https://doi.org/10.1086/734083\">10.1086/734083</a>.","apa":"Nabeel, A., Karichannavar, A., Palathingal, S., Jhawar, J., Brückner, D., Raj M, D., &#38; Guttal, V. (2025). Discovering stochastic dynamical equations from ecological time series data. <i>The American Naturalist</i>. University of Chicago Press. <a href=\"https://doi.org/10.1086/734083\">https://doi.org/10.1086/734083</a>"},"abstract":[{"text":"Theoretical studies have shown that stochasticity can affect the dynamics of ecosystems in counterintuitive ways. However, without knowing the equations governing the dynamics of populations or ecosystems, it is difficult to ascertain the role of stochasticity in real datasets. Therefore, the inverse problem of inferring the governing stochastic equations from datasets is important. Here, we present an equation discovery methodology that takes time series data of state variables as input and outputs a stochastic differential equation. We achieve this by combining traditional approaches from stochastic calculus with the equation discovery techniques. We demonstrate the generality of the method via several applications. First, we deliberately choose various stochastic models with fundamentally different governing equations, yet they produce nearly identical steady-state distributions. We show that we can recover the correct underlying equations, and thus infer the structure of their stability, accurately from the analysis of time series data alone. We demonstrate our method on two real-world datasets—fish schooling and single-cell migration—that have vastly different spatiotemporal scales and dynamics. We illustrate various limitations and potential pitfalls of the method and how to overcome them via diagnostic measures. Finally, we provide our open-source code via a package named PyDaDDy (Python Library for Data-Driven Dynamics).","lang":"eng"}],"doi":"10.1086/734083","related_material":{"record":[{"status":"public","relation":"software","id":"20121"}]},"intvolume":"       205","publication_status":"published","type":"journal_article","publisher":"University of Chicago Press","language":[{"iso":"eng"}],"volume":205,"quality_controlled":"1","year":"2025","month":"04","page":"E100-E117","issue":"4","article_processing_charge":"No","isi":1},{"doi":"10.3390/biology14080930","citation":{"ama":"Rosani U, Altan N, Venier P, Bortoletto E, Volpi N, Bernecky C. Ancestral origin and functional expression of a hyaluronic acid pathway complement in mussels. <i>Biology</i>. 2025;14(8). doi:<a href=\"https://doi.org/10.3390/biology14080930\">10.3390/biology14080930</a>","short":"U. Rosani, N. Altan, P. Venier, E. Bortoletto, N. Volpi, C. Bernecky, Biology 14 (2025).","chicago":"Rosani, Umberto, Nehir Altan, Paola Venier, Enrico Bortoletto, Nicola Volpi, and Carrie Bernecky. “Ancestral Origin and Functional Expression of a Hyaluronic Acid Pathway Complement in Mussels.” <i>Biology</i>. MDPI, 2025. <a href=\"https://doi.org/10.3390/biology14080930\">https://doi.org/10.3390/biology14080930</a>.","ieee":"U. Rosani, N. Altan, P. Venier, E. Bortoletto, N. Volpi, and C. Bernecky, “Ancestral origin and functional expression of a hyaluronic acid pathway complement in mussels,” <i>Biology</i>, vol. 14, no. 8. MDPI, 2025.","ista":"Rosani U, Altan N, Venier P, Bortoletto E, Volpi N, Bernecky C. 2025. Ancestral origin and functional expression of a hyaluronic acid pathway complement in mussels. Biology. 14(8), 930.","apa":"Rosani, U., Altan, N., Venier, P., Bortoletto, E., Volpi, N., &#38; Bernecky, C. (2025). Ancestral origin and functional expression of a hyaluronic acid pathway complement in mussels. <i>Biology</i>. MDPI. <a href=\"https://doi.org/10.3390/biology14080930\">https://doi.org/10.3390/biology14080930</a>","mla":"Rosani, Umberto, et al. “Ancestral Origin and Functional Expression of a Hyaluronic Acid Pathway Complement in Mussels.” <i>Biology</i>, vol. 14, no. 8, 930, MDPI, 2025, doi:<a href=\"https://doi.org/10.3390/biology14080930\">10.3390/biology14080930</a>."},"abstract":[{"lang":"eng","text":"Hyaluronic acid (HA) is a key extracellular matrix component of vertebrates, where it mediates cell adhesion, immune regulation, and tissue remodeling through its interaction with specific receptors. Although HA has been detected in a few invertebrate species, the lack of fundamental components of the molecular HA pathway poses relevant objections about its functional role in these species. Mining genomic and transcriptomic data, we considered the conservation of the gene locus encoding for the extracellular link protein (XLINK) in marine mussels as well as its expression patterns. Structural and phylogenetic analyses were undertaken to evaluate possible similarities with vertebrate orthologs and to infer the origin of this gene in invertebrates. Biochemical analysis was used to quantify HA in tissues of Mytilus galloprovincialis. As a result, we confirm that the mussel can produce HA (up to 1.02 ng/mg in mantle) and that its genome encodes two XLINK gene loci. These loci are conserved in Mytilidae species and show a complex evolutionary path. Mussel XLINK genes appeared to be expressed during developmental stages in three mussel species, ranking in the top 100 expressed genes in M. trossulus at 17 h post-fertilization. In conclusion, the presence of HA and an active gene with the potential to bind HA suggests that mussels have the potential to synthesize and use HA and are among the few invertebrates encoding this gene."}],"publication_status":"published","publisher":"MDPI","type":"journal_article","has_accepted_license":"1","intvolume":"        14","PlanS_conform":"1","quality_controlled":"1","ddc":["570"],"year":"2025","language":[{"iso":"eng"}],"volume":14,"article_processing_charge":"Yes","isi":1,"month":"07","issue":"8","file_date_updated":"2025-07-31T09:11:09Z","date_published":"2025-07-24T00:00:00Z","DOAJ_listed":"1","OA_type":"gold","publication_identifier":{"issn":["2079-7737"]},"external_id":{"isi":["001557922100001"]},"oa":1,"oa_version":"Published Version","article_number":"930","date_created":"2025-07-25T08:28:26Z","_id":"20077","publication":"Biology","file":[{"access_level":"open_access","date_updated":"2025-07-31T09:11:09Z","content_type":"application/pdf","success":1,"file_id":"20097","file_name":"2025_Biology_Rosani.pdf","creator":"dernst","date_created":"2025-07-31T09:11:09Z","checksum":"f5e059e66803fa54249c1db029aef0f6","file_size":1885781,"relation":"main_file"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2025-09-30T14:10:07Z","title":"Ancestral origin and functional expression of a hyaluronic acid pathway complement in mussels","author":[{"last_name":"Rosani","first_name":"Umberto","full_name":"Rosani, Umberto"},{"full_name":"Altan, Nehir","first_name":"Nehir","last_name":"Altan"},{"full_name":"Venier, Paola","first_name":"Paola","last_name":"Venier"},{"first_name":"Enrico","last_name":"Bortoletto","full_name":"Bortoletto, Enrico"},{"first_name":"Nicola","last_name":"Volpi","full_name":"Volpi, Nicola"},{"id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","first_name":"Carrie A","last_name":"Bernecky","orcid":"0000-0003-0893-7036","full_name":"Bernecky, Carrie A"}],"OA_place":"publisher","article_type":"original","acknowledgement":"This research was funded by the Italian Ministry of University and Research (MIUR), grant ID: P2022JEEMT (Developing a tool for the study of haplotype diversity in Mytilus galloprovincialis (HAMIGA)).","day":"24","department":[{"_id":"CaBe"}]},{"issue":"3","month":"07","isi":1,"article_processing_charge":"No","volume":51,"language":[{"iso":"eng"}],"year":"2025","quality_controlled":"1","intvolume":"        51","type":"journal_article","publisher":"Elsevier","publication_status":"published","abstract":[{"lang":"eng","text":"Research question: Is LINC01638 involved in regulation of epithelial-to-mesenchymal transition (EMT) in endometriosis?\r\nDesign: A prospective patient cohort study was combined with functional experiments in the 12Z endometriosis epithelial cell line to investigate the role of LINC01638 in endometriosis. Eutopic endometrial samples were collected by curettage, and ectopic endometrial lesion samples were collected by laparoscopic surgery from 24 control patients and 41 patients with endometriosis. The phenotype of 12Z cells was assessed following LINC01638 knockdown using siRNA, performing proliferation, adhesion, migration and invasion assays, as well as assessing apoptosis and cell cycle changes with flow cytometry assays. In order to assess the relationship between LINC01638 and histone deacetylase class 1 enzyme (HDAC1), LINC01638 knockdown was combined with HDAC inhibition with the specific HDAC inhibitor romidepsin.\r\nResults: LINC01638 was up-regulated in the epithelial layer of endometriotic lesions, and LINC01638 knockdown in 12Z cells led to reduced proliferation, adhesion, migration and invasion. The reduction in proliferation was associated with increased p21 and p27 expression, and G1 phase arrest. Further analysis of LINC01638 control and knockdown cells revealed that a number of transcription factors associated with EMT are down-regulated in knockdown cells, along with the cytoskeleton regulatory gene RHOB, while HDAC1 was up-regulated. Chromatin immunoprecipitation analysis and HDAC1 inhibitory treatment combined with LINC01638 knockdown indicated that LINC01638 regulates RHOB expression via HDAC1-mediated promoter deacetylation. RHOB is up-regulated in the epithelial layer of endometriotic lesions compared with eutopic endometrium, supporting a role in the disease.\r\nConclusions: LINC01638 is an epigenetic regulator of the pathogenesis of endometriosis, promoting proliferation and EMT of endometriotic lesions."}],"citation":{"mla":"Yotova, Iveta, et al. “LINC01638 Promotes Epithelial-to-Mesenchymal Transition in Endometriosis Epithelial Cells by up-Regulating RHOB via HDAC1 Suppression.” <i>Reproductive Biomedicine Online</i>, vol. 51, no. 3, 104942, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.rbmo.2025.104942\">10.1016/j.rbmo.2025.104942</a>.","apa":"Yotova, I., Proestling, K., Pauler, F., Rainer, L., Kaup, L., Heine, J., … Hudson, Q. J. (2025). LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression. <i>Reproductive Biomedicine Online</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.rbmo.2025.104942\">https://doi.org/10.1016/j.rbmo.2025.104942</a>","ieee":"I. Yotova <i>et al.</i>, “LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression,” <i>Reproductive Biomedicine Online</i>, vol. 51, no. 3. Elsevier, 2025.","chicago":"Yotova, Iveta, Katharina Proestling, Florian Pauler, Lisa Rainer, Leonie Kaup, Jana Heine, Lejla Sandrieser, René Wenzl, and Quanah J. Hudson. “LINC01638 Promotes Epithelial-to-Mesenchymal Transition in Endometriosis Epithelial Cells by up-Regulating RHOB via HDAC1 Suppression.” <i>Reproductive Biomedicine Online</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.rbmo.2025.104942\">https://doi.org/10.1016/j.rbmo.2025.104942</a>.","ista":"Yotova I, Proestling K, Pauler F, Rainer L, Kaup L, Heine J, Sandrieser L, Wenzl R, Hudson QJ. 2025. LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression. Reproductive Biomedicine Online. 51(3), 104942.","short":"I. Yotova, K. Proestling, F. Pauler, L. Rainer, L. Kaup, J. Heine, L. Sandrieser, R. Wenzl, Q.J. Hudson, Reproductive Biomedicine Online 51 (2025).","ama":"Yotova I, Proestling K, Pauler F, et al. LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression. <i>Reproductive Biomedicine Online</i>. 2025;51(3). doi:<a href=\"https://doi.org/10.1016/j.rbmo.2025.104942\">10.1016/j.rbmo.2025.104942</a>"},"doi":"10.1016/j.rbmo.2025.104942","scopus_import":"1","department":[{"_id":"SiHi"}],"day":"17","article_type":"original","acknowledgement":"The authors wish to thank all the participants and health professionals involved in this study. In addition, the authors wish to thank technical assistants Barbara Widmar, Matthias Witzmann-Stern and Isabella Haslinger for their work assisting with this study; and Simon Hippenmeyer for access to bioinformatic infrastructure and resources.\r\nOpen access funding was provided by the Medical University of Vienna.","title":"LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression","author":[{"full_name":"Yotova, Iveta","first_name":"Iveta","last_name":"Yotova"},{"full_name":"Proestling, Katharina","last_name":"Proestling","first_name":"Katharina"},{"id":"48EA0138-F248-11E8-B48F-1D18A9856A87","last_name":"Pauler","first_name":"Florian","full_name":"Pauler, Florian","orcid":"0000-0002-7462-0048"},{"last_name":"Rainer","first_name":"Lisa","full_name":"Rainer, Lisa"},{"first_name":"Leonie","last_name":"Kaup","full_name":"Kaup, Leonie"},{"full_name":"Heine, Jana","first_name":"Jana","last_name":"Heine"},{"last_name":"Sandrieser","first_name":"Lejla","full_name":"Sandrieser, Lejla"},{"first_name":"René","last_name":"Wenzl","full_name":"Wenzl, René"},{"full_name":"Hudson, Quanah J.","last_name":"Hudson","first_name":"Quanah J."}],"date_updated":"2025-09-30T14:10:46Z","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Reproductive Biomedicine Online","pmid":1,"_id":"20079","oa_version":"None","article_number":"104942","date_created":"2025-07-27T22:01:25Z","external_id":{"isi":["001549819000002"],"pmid":["40680553"]},"publication_identifier":{"eissn":["1472-6491"],"issn":["1472-6483"]},"OA_type":"closed access","date_published":"2025-07-17T00:00:00Z"},{"pmid":1,"project":[{"call_identifier":"FP7","name":"Hormonal cross-talk in plant organogenesis","_id":"253FCA6A-B435-11E9-9278-68D0E5697425","grant_number":"207362"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"_id":"20080","oa_version":"Published Version","article_number":"1612366","date_created":"2025-07-27T22:01:26Z","file":[{"access_level":"open_access","success":1,"content_type":"application/pdf","date_updated":"2025-07-31T07:28:54Z","file_id":"20093","file_name":"2025_FrontiersPlantSc_Gallemi.pdf","creator":"dernst","file_size":3665187,"date_created":"2025-07-31T07:28:54Z","checksum":"9e6b8b53ba56d4a24a9bd91cf6d2dc58","relation":"main_file"}],"publication":"Frontiers in Plant Science","OA_type":"gold","publication_identifier":{"eissn":["1664-462X"]},"date_published":"2025-07-04T00:00:00Z","DOAJ_listed":"1","external_id":{"isi":["001530690900001"],"pmid":["40688689"]},"oa":1,"author":[{"first_name":"Marçal","last_name":"Gallemi","full_name":"Gallemi, Marçal","orcid":"0000-0003-4675-6893","id":"460C6802-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Montesinos López","first_name":"Juan C","orcid":"0000-0001-9179-6099","full_name":"Montesinos López, Juan C","id":"310A8E3E-F248-11E8-B48F-1D18A9856A87"},{"id":"18e95355-e05a-11ea-a9c0-8fba1b89e83a","first_name":"Nikola","last_name":"Zarevski","full_name":"Zarevski, Nikola"},{"last_name":"Pribyl","first_name":"Jan","full_name":"Pribyl, Jan"},{"full_name":"Skládal, Petr","first_name":"Petr","last_name":"Skládal"},{"first_name":"Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","first_name":"Eva","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739"}],"title":"Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties","day":"04","department":[{"_id":"EdHa"},{"_id":"EvBe"},{"_id":"CaGu"}],"ec_funded":1,"article_type":"original","APC_amount":"3642,79 EUR","OA_place":"publisher","acknowledgement":"The author(s) declare that financial support was received for the research and/or publication of this article. This work was supported by grants from the European Research Council (Starting Independent Research Grant ERC-2007-Stg- 207362-HCPO to EB) and MG was recipient of an IST Interdisciplinary project (IC1022IPC03).\r\nWe acknowledge Jaume F. Martı́nez Garcı́a for phyAphyB mutant seeds. We acknowledge CF Nanobiotechnology of CIISB, Instruct-CZ Centre, supported by MEYS CR (LM2018127). We gratefully acknowledge support by the Scientific Service Units at ISTA, including the Imaging and Optics and Lab Support facilities and Library. We thank Stefan Riegler for the efforts to establish immunodetection method.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2026-05-20T07:53:03Z","status":"public","type":"journal_article","corr_author":"1","publisher":"Frontiers Media","publication_status":"published","PlanS_conform":"1","intvolume":"        16","has_accepted_license":"1","doi":"10.3389/fpls.2025.1612366","scopus_import":"1","abstract":[{"text":"Introduction: Acid-growth theory has been postulated in the 70s to explain the rapid elongation of plant cells in response to the hormone auxin. More recently, it has been demonstrated that activation of the proton ATPs pump (H+-ATPs) promoting acidification of the apoplast is the principal mechanism by which auxin and other hormones such as brassinosteroids (BR) induce cell elongation. Despite these advances, the impact of this acidification on the mechanical properties of the cell wall remained largely unexplored.\r\n\r\nMethods: Here, we use elongation assays of Arabidopsis thaliana hypocotyls and Atomic Force Microscopy (AFM) to correlate hormone-induced tissue elongation and local changes in cell wall mechanical properties. Furthermore, employing transgenic lines over-expressing Pectin Methyl Esterase (PME), along with calcium chelators, we investigate the effect of pectin modification in hormone-driven cell elongation.\r\n\r\nResults: We demonstrate that acidification of apoplast is necessary and sufficient to induce cell elongation through promoting cell wall softening. Moreover, we show that enhanced PME activity can induce both cell wall softening or stiffening in extracellular calcium dependent-manner and that tight control of PME activity is required for proper hypocotyl elongation.\r\n\r\nDiscussion: Our results confirm a dual role of PME in plant cell elongation. However, further investigation is needed to assess the status of pectin following short- or long-term PME treatments in order to determine if pectin methyl-esterification might promote its degradation as well as the role of PME inhibitors upon PME induction.","lang":"eng"}],"citation":{"apa":"Gallemi, M., Montesinos López, J. C., Zarevski, N., Pribyl, J., Skládal, P., Hannezo, E. B., &#38; Benková, E. (2025). Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties. <i>Frontiers in Plant Science</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fpls.2025.1612366\">https://doi.org/10.3389/fpls.2025.1612366</a>","mla":"Gallemi, Marçal, et al. “Dual Role of Pectin Methyl Esterase Activity in the Regulation of Plant Cell Wall Biophysical Properties.” <i>Frontiers in Plant Science</i>, vol. 16, 1612366, Frontiers Media, 2025, doi:<a href=\"https://doi.org/10.3389/fpls.2025.1612366\">10.3389/fpls.2025.1612366</a>.","ieee":"M. Gallemi <i>et al.</i>, “Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties,” <i>Frontiers in Plant Science</i>, vol. 16. Frontiers Media, 2025.","chicago":"Gallemi, Marçal, Juan C Montesinos López, Nikola Zarevski, Jan Pribyl, Petr Skládal, Edouard B Hannezo, and Eva Benková. “Dual Role of Pectin Methyl Esterase Activity in the Regulation of Plant Cell Wall Biophysical Properties.” <i>Frontiers in Plant Science</i>. Frontiers Media, 2025. <a href=\"https://doi.org/10.3389/fpls.2025.1612366\">https://doi.org/10.3389/fpls.2025.1612366</a>.","ista":"Gallemi M, Montesinos López JC, Zarevski N, Pribyl J, Skládal P, Hannezo EB, Benková E. 2025. Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties. Frontiers in Plant Science. 16, 1612366.","short":"M. Gallemi, J.C. Montesinos López, N. Zarevski, J. Pribyl, P. Skládal, E.B. Hannezo, E. Benková, Frontiers in Plant Science 16 (2025).","ama":"Gallemi M, Montesinos López JC, Zarevski N, et al. Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties. <i>Frontiers in Plant Science</i>. 2025;16. doi:<a href=\"https://doi.org/10.3389/fpls.2025.1612366\">10.3389/fpls.2025.1612366</a>"},"isi":1,"article_processing_charge":"Yes","file_date_updated":"2025-07-31T07:28:54Z","month":"07","year":"2025","ddc":["580"],"quality_controlled":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"E-Lib"}],"volume":16,"language":[{"iso":"eng"}]},{"ddc":["570"],"year":"2025","quality_controlled":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"volume":26,"language":[{"iso":"eng"}],"isi":1,"article_processing_charge":"Yes (via OA deal)","page":"1258–1266","file_date_updated":"2025-07-31T08:00:33Z","month":"08","related_material":{"record":[{"relation":"dissertation_contains","id":"20149","status":"public"}],"link":[{"url":"https://ista.ac.at/en/news/bench-pressing-cells/","relation":"press_release","description":"News on ISTA website"}]},"doi":"10.1038/s41590-025-02211-w","scopus_import":"1","abstract":[{"lang":"eng","text":"Efficient immune responses rely on the capacity of leukocytes to traverse diverse and complex tissues. To meet such changing environmental conditions, leukocytes usually adopt an ameboid configuration, using their forward-positioned nucleus as a probe to identify and follow the path of least resistance among pre-existing pores. We show that, in dense environments where even the largest pores preclude free passage, leukocytes position their nucleus behind the centrosome and organelles. The local compression imposed on the cell body by its surroundings triggers assembly of a central F-actin pool, located between cell front and nucleus. Central actin pushes outward to transiently dilate a path for organelles and nucleus. Pools of central and front actin are tightly coupled and experimental depletion of the central pool enhances actin accumulation and protrusion formation at the cell front. Although this shifted balance speeds up cells in permissive environments, migration in restrictive environments is impaired, as the unleashed leading edge dissociates from the trapped cell body. Our findings establish an actin regulatory loop that balances path dilation with advancement of the leading edge to maintain cellular coherence."}],"citation":{"short":"P. Dos Reis Rodrigues, M. Avellaneda Sarrió, N. Canigova, F.R. Gärtner, K. Vaahtomeri, M. Riedl, I. de Vries, J. Merrin, R. Hauschild, Y. Fukui, A. Juanes Garcia, M.K. Sixt, Nature Immunology 26 (2025) 1258–1266.","ama":"Dos Reis Rodrigues P, Avellaneda Sarrió M, Canigova N, et al. Migrating immune cells globally coordinate protrusive forces. <i>Nature Immunology</i>. 2025;26:1258–1266. doi:<a href=\"https://doi.org/10.1038/s41590-025-02211-w\">10.1038/s41590-025-02211-w</a>","ieee":"P. Dos Reis Rodrigues <i>et al.</i>, “Migrating immune cells globally coordinate protrusive forces,” <i>Nature Immunology</i>, vol. 26. Springer Nature, pp. 1258–1266, 2025.","chicago":"Dos Reis Rodrigues, Patricia, Mario Avellaneda Sarrió, Nikola Canigova, Florian R Gärtner, Kari Vaahtomeri, Michael Riedl, Ingrid de Vries, et al. “Migrating Immune Cells Globally Coordinate Protrusive Forces.” <i>Nature Immunology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41590-025-02211-w\">https://doi.org/10.1038/s41590-025-02211-w</a>.","ista":"Dos Reis Rodrigues P, Avellaneda Sarrió M, Canigova N, Gärtner FR, Vaahtomeri K, Riedl M, de Vries I, Merrin J, Hauschild R, Fukui Y, Juanes Garcia A, Sixt MK. 2025. Migrating immune cells globally coordinate protrusive forces. Nature Immunology. 26, 1258–1266.","apa":"Dos Reis Rodrigues, P., Avellaneda Sarrió, M., Canigova, N., Gärtner, F. R., Vaahtomeri, K., Riedl, M., … Sixt, M. K. (2025). Migrating immune cells globally coordinate protrusive forces. <i>Nature Immunology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41590-025-02211-w\">https://doi.org/10.1038/s41590-025-02211-w</a>","mla":"Dos Reis Rodrigues, Patricia, et al. “Migrating Immune Cells Globally Coordinate Protrusive Forces.” <i>Nature Immunology</i>, vol. 26, Springer Nature, 2025, pp. 1258–1266, doi:<a href=\"https://doi.org/10.1038/s41590-025-02211-w\">10.1038/s41590-025-02211-w</a>."},"publisher":"Springer Nature","type":"journal_article","corr_author":"1","publication_status":"published","PlanS_conform":"1","intvolume":"        26","has_accepted_license":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2026-04-28T13:26:50Z","status":"public","author":[{"id":"26E95904-5160-11E9-9C0B-C5B0DC97E90F","full_name":"Dos Reis Rodrigues, Patricia","orcid":"0000-0003-1681-508X","last_name":"Dos Reis Rodrigues","first_name":"Patricia"},{"id":"DC4BA84C-56E6-11EA-AD5D-348C3DDC885E","orcid":"0000-0001-6406-524X","full_name":"Avellaneda Sarrió, Mario","last_name":"Avellaneda Sarrió","first_name":"Mario"},{"id":"3795523E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8518-5926","full_name":"Canigova, Nikola","first_name":"Nikola","last_name":"Canigova"},{"orcid":"0000-0001-6120-3723","full_name":"Gärtner, Florian R","first_name":"Florian R","last_name":"Gärtner","id":"397A88EE-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-7829-3518","full_name":"Vaahtomeri, Kari","first_name":"Kari","last_name":"Vaahtomeri","id":"368EE576-F248-11E8-B48F-1D18A9856A87"},{"id":"3BE60946-F248-11E8-B48F-1D18A9856A87","first_name":"Michael","last_name":"Riedl","full_name":"Riedl, Michael","orcid":"0000-0003-4844-6311"},{"full_name":"De Vries, Ingrid","last_name":"De Vries","first_name":"Ingrid","id":"4C7D837E-F248-11E8-B48F-1D18A9856A87"},{"id":"4515C308-F248-11E8-B48F-1D18A9856A87","last_name":"Merrin","first_name":"Jack","orcid":"0000-0001-5145-4609","full_name":"Merrin, Jack"},{"last_name":"Hauschild","first_name":"Robert","full_name":"Hauschild, Robert","orcid":"0000-0001-9843-3522","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Fukui, Yoshinori","last_name":"Fukui","first_name":"Yoshinori"},{"id":"40F05888-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1009-9652","full_name":"Juanes Garcia, Alba","first_name":"Alba","last_name":"Juanes Garcia"},{"last_name":"Sixt","first_name":"Michael K","orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"title":"Migrating immune cells globally coordinate protrusive forces","department":[{"_id":"MiSi"},{"_id":"NanoFab"},{"_id":"Bio"}],"day":"01","OA_place":"publisher","article_type":"letter_note","acknowledgement":"This research was supported by the Scientific Service Units of ISTA through resources provided by the Imaging and Optics, Preclinical and Lab Support Facilities. In particular, we thank M. A. Symth and F. G. G. Leite, from the Virus Service Team, who helped generating the lentiviral particles used in this study. We thank all the members of the Sixt group for valuable discussions and feedback, in particular, I. Mayer, for helping with T cell isolation and Z. (P.) Li for providing the Actin–GFP DC line. We are also thankful to J. Mandl and C. Shen for their feedback during the writing of this manuscript. This work was supported by a European Research Council grant ERC-SyG 101071793 to M.S. M.J.A. was supported by an HFSP Postdoctoral Fellowship LTF 177 2021 and A.J.G. by a Lise Meitner Fellowship of the FWF (Austrian Science Fund). Y.F. was supported by the AMED-CREST (JP19gm1310005), the Medical Research Center Initiative for High Depth Omics and CURE:JPMXP1323015486 for MIB, Kyushu University. Open access funding provided by Institute of Science and Technology (IST Austria).","OA_type":"hybrid","publication_identifier":{"issn":["1529-2908"],"eissn":["1529-2916"]},"date_published":"2025-08-01T00:00:00Z","external_id":{"isi":["001529134300001"],"pmid":["40664976"]},"oa":1,"pmid":1,"project":[{"grant_number":"101071793","_id":"bd91e723-d553-11ed-ba76-fe7eeb2185fd","name":"Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces"},{"_id":"c092d618-5a5b-11eb-8a69-f92e1e843fc8","grant_number":"944-2020","name":"Bioelectric patrolling: the role of the local membrane potential in immune cell migration"}],"_id":"20082","oa_version":"Published Version","date_created":"2025-07-27T22:01:26Z","file":[{"access_level":"open_access","date_updated":"2025-07-31T08:00:33Z","success":1,"content_type":"application/pdf","file_id":"20096","file_name":"2025_NatureImmunology_ReisRodrigues.pdf","creator":"dernst","checksum":"0c725123dca7797c682609bff2c4c5ac","date_created":"2025-07-31T08:00:33Z","file_size":13514646,"relation":"main_file"}],"publication":"Nature Immunology"},{"oa":1,"date_published":"2025-07-15T00:00:00Z","DOAJ_listed":"1","OA_type":"gold","publication_identifier":{"eissn":["2752-5295"]},"publication":"Environmental Research: Climate","file":[{"file_size":2807041,"checksum":"ca679496767021e792b0378c48fdee8c","date_created":"2025-08-04T07:38:14Z","relation":"main_file","file_name":"2025_EnvironResearchClimate_Hwong.pdf","creator":"dernst","file_id":"20108","access_level":"open_access","content_type":"application/pdf","success":1,"date_updated":"2025-08-04T07:38:14Z"}],"article_number":"035005","oa_version":"Published Version","date_created":"2025-07-31T14:03:16Z","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"_id":"20098","status":"public","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2025-08-04T07:46:33Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","OA_place":"publisher","acknowledgement":"We thank Marina Andrijevic, Giacomo Falchetta, Samuel Lüthi, Caroline Muller, Carl Schleussner, and Adriano Vinca for providing useful ideas and feedback for this work. YLH is supported by funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska‐Curie Grant No. 101034413. EB, MW, and YQ are supported by the European Union’s Horizon Europe research and innovation programme under Grant Agreement No. 101081369 (SPARCCLE). We also thank the two anonymous reviewers for providing helpful feedback that greatly improved this manuscript.","department":[{"_id":"CaMu"}],"day":"15","ec_funded":1,"author":[{"first_name":"Yi-Ling","last_name":"Hwong","full_name":"Hwong, Yi-Ling","orcid":"0000-0001-9281-3479","id":"1217aa61-4dd1-11ec-9ac3-f2ba3f17ee22"},{"first_name":"Edward","last_name":"Byers","full_name":"Byers, Edward"},{"first_name":"Michaela","last_name":"Werning","full_name":"Werning, Michaela"},{"last_name":"Quilcaille","first_name":"Yann","full_name":"Quilcaille, Yann"}],"title":"Sustainable development key to limiting climate change-driven wildfire damages","citation":{"ama":"Hwong Y-L, Byers E, Werning M, Quilcaille Y. Sustainable development key to limiting climate change-driven wildfire damages. <i>Environmental Research: Climate</i>. 2025;4(3). doi:<a href=\"https://doi.org/10.1088/2752-5295/adec11\">10.1088/2752-5295/adec11</a>","short":"Y.-L. Hwong, E. Byers, M. Werning, Y. Quilcaille, Environmental Research: Climate 4 (2025).","chicago":"Hwong, Yi-Ling, Edward Byers, Michaela Werning, and Yann Quilcaille. “Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages.” <i>Environmental Research: Climate</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/2752-5295/adec11\">https://doi.org/10.1088/2752-5295/adec11</a>.","ista":"Hwong Y-L, Byers E, Werning M, Quilcaille Y. 2025. Sustainable development key to limiting climate change-driven wildfire damages. Environmental Research: Climate. 4(3), 035005.","ieee":"Y.-L. Hwong, E. Byers, M. Werning, and Y. Quilcaille, “Sustainable development key to limiting climate change-driven wildfire damages,” <i>Environmental Research: Climate</i>, vol. 4, no. 3. IOP Publishing, 2025.","apa":"Hwong, Y.-L., Byers, E., Werning, M., &#38; Quilcaille, Y. (2025). Sustainable development key to limiting climate change-driven wildfire damages. <i>Environmental Research: Climate</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/2752-5295/adec11\">https://doi.org/10.1088/2752-5295/adec11</a>","mla":"Hwong, Yi-Ling, et al. “Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages.” <i>Environmental Research: Climate</i>, vol. 4, no. 3, 035005, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/2752-5295/adec11\">10.1088/2752-5295/adec11</a>."},"abstract":[{"text":"Climate change is causing wildfires to become more frequent and intense. While predicting burned areas using bioclimatic and anthropogenic factors is an active research area, few studies have examined what drives the economic damages of wildfires. Our study aims to fill this gap by analyzing key factors influencing global economic wildfire damages and projecting future damages under three shared socioeconomic pathways (SSPs). We apply regression analyses to identify significant predictors of economic wildfire damages at country levels and use the fitted model to project future damages under SSP126, SSP245, and SSP370. Results show that the human vulnerability index (HVI), reflecting socioeconomic conditions, is the strongest predictor of historical wildfire damages, followed by water vapor pressure deficit during the fire season and population density around forested areas. We found high population density to be associated with lower damages. These findings contrast with studies of burned areas, where climate factors are more dominant. Our model projects that by 2070, average global economic wildfire damages will be three times higher under SSP370 than SSP126. Our model also shows that following SSP126 not only reduces wildfire damages but also lessens the inequalities in damage distribution across countries. This pathway’s dual focus on equitable socioeconomic progress and climate action potentially enhances a country’s resilience that helps mitigate wildfire damages. Our analyses also indicate that strong socioeconomic development can offset wildfire damages associated with climate hazards, although this is less certain under SSP370. SSP126’s integrated approach improves both socioeconomic conditions and limits global warming, providing substantial benefits to less developed countries while still reducing damages in developed nations, despite their already low HVI scores. Our work complements existing research on burned areas and underscores the importance of sustainable development and international collaboration in reducing the economic damages of wildfires.","lang":"eng"}],"scopus_import":"1","related_material":{"record":[{"id":"20107","relation":"research_data","status":"public"}]},"doi":"10.1088/2752-5295/adec11","has_accepted_license":"1","intvolume":"         4","PlanS_conform":"1","publication_status":"published","corr_author":"1","publisher":"IOP Publishing","type":"journal_article","language":[{"iso":"eng"}],"volume":4,"quality_controlled":"1","ddc":["550"],"year":"2025","month":"07","issue":"3","file_date_updated":"2025-08-04T07:38:14Z","article_processing_charge":"Yes"},{"publication_identifier":{"issn":["2639-1856"],"eissn":["2211-1247"]},"OA_type":"gold","date_published":"2025-08-01T00:00:00Z","DOAJ_listed":"1","external_id":{"isi":["001544472300002"]},"oa":1,"project":[{"grant_number":"692692","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse"},{"name":"Synaptic computations of the hippocampal CA3 circuitry","call_identifier":"H2020","grant_number":"101026635","_id":"fc2be41b-9c52-11eb-aca3-faa90aa144e9"},{"grant_number":"P36232","_id":"bd88be38-d553-11ed-ba76-81d5a70a6ef5","name":"Mechanisms of GABA release in hippocampal circuits"},{"name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"_id":"20099","article_number":"116080","oa_version":"Published Version","date_created":"2025-08-03T22:01:30Z","file":[{"content_type":"application/pdf","success":1,"date_updated":"2025-08-04T06:53:07Z","access_level":"open_access","file_id":"20106","creator":"dernst","file_name":"2025_CellReports_Watson.pdf","relation":"main_file","file_size":27695214,"date_created":"2025-08-04T06:53:07Z","checksum":"556ff9760661ecd23949d75031043b1f"}],"publication":"Cell Reports","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2025-09-30T14:12:02Z","status":"public","title":"Cell-specific wiring routes information flow through hippocampal CA3","author":[{"first_name":"Jake","last_name":"Watson","orcid":"0000-0002-8698-3823","full_name":"Watson, Jake","id":"63836096-4690-11EA-BD4E-32803DDC885E"},{"id":"2F55A9DE-F248-11E8-B48F-1D18A9856A87","full_name":"Vargas Barroso, Victor M","first_name":"Victor M","last_name":"Vargas Barroso"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas","first_name":"Peter M","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M"}],"department":[{"_id":"PeJo"}],"day":"01","ec_funded":1,"OA_place":"publisher","article_type":"original","acknowledgement":"We thank Andrea Navas-Olive and Rebecca J. Morse-Mora for critically reading an earlier version of the manuscript. We also thank Florian Marr and Christina Altmutter for excellent technical assistance, Alois Schlögl for programming and data-handling assistance, Todor Asenov for technical support, and Eleftheria Kralli-Beller for manuscript editing. This research was supported by the Scientific Services Units (SSUs) of ISTA. We are particularly grateful for assistance from the Imaging and Optics Facility, Preclinical Facility, Lab Support Facility, and Miba Machine Shop. The project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 692692 to P.J., Marie Skłodowska-Curie Actions Individual Fellowship no. 101026635 to J.F.W., and an ISTplus Fellowship through Marie Skłodowska-Curie grant agreement no. 754411 to V.V.-B.), the Austrian Science Fund (P 36232-B, PAT 4178023, and Cluster of Excellence 10.55776/COE16 to P.J.), and a CONACyT fellowship (289638 to V.V.-B.) and was supported by a non-stipendiary EMBO fellowship (ALTF 756–2020 to J.F.W.).","doi":"10.1016/j.celrep.2025.116080","scopus_import":"1","abstract":[{"lang":"eng","text":"The hippocampus, critical for learning and memory, is dogmatically described as a trisynaptic circuit where dentate gyrus granule cells (GCs), CA3 pyramidal neurons (PNs), and CA1 PNs are serially connected. However, CA3 also forms an autoassociative network, and its PNs have diverse morphologies, intrinsic properties, and GC input levels. How PN subtypes compose this recurrent network is unknown. To determine the synaptic arrangement of identified CA3 PNs, we combine multicellular patch-clamp recording and post hoc morphological analysis in mouse hippocampal slices. PNs can be divided into distinct “superficial” and “deep” subclasses, the latter including previously reported “athorny” cells. Subclasses have distinct input-output transformations and asymmetric connectivity, which is more abundant from superficial to deep PNs, splitting CA3 locally into two parallel recurrent networks. Coincident spontaneous inhibition occurs frequently within but not between subclasses, implying subclass-specific inhibitory innervation. Our results suggest two separately controlled sublayers for parallel information processing in hippocampal CA3."}],"citation":{"short":"J. Watson, V.M. Vargas Barroso, P.M. Jonas, Cell Reports 44 (2025).","ama":"Watson J, Vargas Barroso VM, Jonas PM. Cell-specific wiring routes information flow through hippocampal CA3. <i>Cell Reports</i>. 2025;44(8). doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116080\">10.1016/j.celrep.2025.116080</a>","ieee":"J. Watson, V. M. Vargas Barroso, and P. M. Jonas, “Cell-specific wiring routes information flow through hippocampal CA3,” <i>Cell Reports</i>, vol. 44, no. 8. Elsevier, 2025.","chicago":"Watson, Jake, Victor M Vargas Barroso, and Peter M Jonas. “Cell-Specific Wiring Routes Information Flow through Hippocampal CA3.” <i>Cell Reports</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.celrep.2025.116080\">https://doi.org/10.1016/j.celrep.2025.116080</a>.","ista":"Watson J, Vargas Barroso VM, Jonas PM. 2025. Cell-specific wiring routes information flow through hippocampal CA3. Cell Reports. 44(8), 116080.","mla":"Watson, Jake, et al. “Cell-Specific Wiring Routes Information Flow through Hippocampal CA3.” <i>Cell Reports</i>, vol. 44, no. 8, 116080, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116080\">10.1016/j.celrep.2025.116080</a>.","apa":"Watson, J., Vargas Barroso, V. M., &#38; Jonas, P. M. (2025). Cell-specific wiring routes information flow through hippocampal CA3. <i>Cell Reports</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.celrep.2025.116080\">https://doi.org/10.1016/j.celrep.2025.116080</a>"},"corr_author":"1","type":"journal_article","publisher":"Elsevier","publication_status":"published","PlanS_conform":"1","intvolume":"        44","has_accepted_license":"1","year":"2025","ddc":["570"],"quality_controlled":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"M-Shop"}],"volume":44,"language":[{"iso":"eng"}],"isi":1,"article_processing_charge":"Yes","issue":"8","file_date_updated":"2025-08-04T06:53:07Z","month":"08"},{"volume":27,"language":[{"iso":"eng"}],"year":"2025","ddc":["000","570"],"quality_controlled":"1","file_date_updated":"2025-08-04T06:25:23Z","page":"3292-3298","month":"06","isi":1,"article_processing_charge":"Yes","abstract":[{"text":"A key step in protein structure prediction involves the detection of co-evolving pairs of residues, a signal for spatial proximity. This information is gleaned from multiple sequence alignment and underscores Alphafold’s structure prediction for almost every known protein. A simple means to create proteins beyond those found in nature, is by unnaturally fusing together two known proteins or protein parts. Here we demonstrate that structured peptides are predicted with significantly reduced accuracy when added to the terminal ends of scaffold proteins. Appending the multiple sequence alignment for the individual peptide tags to that of the scaffold protein often restores prediction accuracy. This work suggests that this windowed multiple sequence alignment approach can be a useful tool for predicting the structure of fused, chimeric proteins.","lang":"eng"}],"citation":{"apa":"Vedula, S., Bronstein, A. M., &#38; Marx, A. (2025). Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment. <i>Computational and Structural Biotechnology Journal</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.csbj.2025.07.039\">https://doi.org/10.1016/j.csbj.2025.07.039</a>","mla":"Vedula, Sanketh, et al. “Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.” <i>Computational and Structural Biotechnology Journal</i>, vol. 27, Elsevier, 2025, pp. 3292–98, doi:<a href=\"https://doi.org/10.1016/j.csbj.2025.07.039\">10.1016/j.csbj.2025.07.039</a>.","ieee":"S. Vedula, A. M. Bronstein, and A. Marx, “Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment,” <i>Computational and Structural Biotechnology Journal</i>, vol. 27. Elsevier, pp. 3292–3298, 2025.","chicago":"Vedula, Sanketh, Alex M. Bronstein, and Ailie Marx. “Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.” <i>Computational and Structural Biotechnology Journal</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.csbj.2025.07.039\">https://doi.org/10.1016/j.csbj.2025.07.039</a>.","ista":"Vedula S, Bronstein AM, Marx A. 2025. Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment. Computational and Structural Biotechnology Journal. 27, 3292–3298.","ama":"Vedula S, Bronstein AM, Marx A. Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment. <i>Computational and Structural Biotechnology Journal</i>. 2025;27:3292-3298. doi:<a href=\"https://doi.org/10.1016/j.csbj.2025.07.039\">10.1016/j.csbj.2025.07.039</a>","short":"S. Vedula, A.M. Bronstein, A. Marx, Computational and Structural Biotechnology Journal 27 (2025) 3292–3298."},"doi":"10.1016/j.csbj.2025.07.039","related_material":{"link":[{"url":"https://github.com/sankethvedula/AFChimera","relation":"software"}],"record":[{"status":"public","relation":"software","id":"20103"}]},"scopus_import":"1","intvolume":"        27","PlanS_conform":"1","has_accepted_license":"1","type":"journal_article","publisher":"Elsevier","publication_status":"published","date_updated":"2025-11-27T14:09:59Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"27","department":[{"_id":"AlBr"}],"acknowledgement":"AM acknowledges the financial support of the Helmsley Fellowships Program for Sustainability and Health. AMB is supported by the Schmidt Chair in Artificial Intelligence.","OA_place":"publisher","article_type":"original","title":"Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment","author":[{"id":"94f2fe44-70fa-11f0-b76b-92922c09452b","full_name":"Vedula, Sanketh","first_name":"Sanketh","last_name":"Vedula"},{"id":"58f3726e-7cba-11ef-ad8b-e6e8cb3904e6","full_name":"Bronstein, Alexander","orcid":"0000-0001-9699-8730","last_name":"Bronstein","first_name":"Alexander"},{"full_name":"Marx, Ailie","last_name":"Marx","first_name":"Ailie"}],"oa":1,"external_id":{"isi":["001583543100001"]},"publication_identifier":{"eissn":["2001-0370"]},"OA_type":"gold","DOAJ_listed":"1","date_published":"2025-06-27T00:00:00Z","file":[{"date_created":"2025-08-04T06:25:23Z","checksum":"78d01f30fc1dc11dd2bd1d7bb7ac8a62","file_size":6609770,"relation":"main_file","file_name":"2025_CompStrucBiotechJour_Vedula.pdf","creator":"dernst","file_id":"20104","access_level":"open_access","date_updated":"2025-08-04T06:25:23Z","content_type":"application/pdf","success":1}],"publication":"Computational and Structural Biotechnology Journal","_id":"20100","date_created":"2025-08-03T22:01:31Z","oa_version":"Published Version"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","date_updated":"2025-12-30T09:25:45Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"author":[{"full_name":"Raffini, Francesca","first_name":"Francesca","last_name":"Raffini"},{"full_name":"De Jode, Aurélien","first_name":"Aurélien","last_name":"De Jode"},{"full_name":"Johannesson, Kerstin","first_name":"Kerstin","last_name":"Johannesson"},{"full_name":"Faria, Rui","first_name":"Rui","last_name":"Faria"},{"first_name":"Zuzanna B.","last_name":"Zagrodzka","full_name":"Zagrodzka, Zuzanna B."},{"first_name":"Anja M","last_name":"Westram","orcid":"0000-0003-1050-4969","full_name":"Westram, Anja M","id":"3C147470-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Juan","last_name":"Galindo","full_name":"Galindo, Juan"},{"first_name":"Emilio","last_name":"Rolán-Alvarez","full_name":"Rolán-Alvarez, Emilio"},{"full_name":"Butlin, Roger K.","first_name":"Roger K.","last_name":"Butlin"}],"title":"Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail","acknowledgement":"This study was supported by European Research Council grant 693030-BARRIERS to RKB; the Swedish Research Council (grant number 2021-04191) to KJ; the Portuguese Foundation for Science and Technology (FCT: 2020.00275.CEECIND and PTDC/BIA-EVL/1614/2021) to RF; grant PID2022-137935NB-I00 by MICIU/AEI/ 10.13039/501100011033/and ERDF/EU (ED431C 2020-05) to JG, grant PID2021-124930NB-I00 funded by MICIU/AEI/ 10.13039/501100011033/and ERDF/EU to ERA, Xunta de Galicia (ED431C 2024/22), Centro singular de Investigación de Galicia accreditation 2024-2027 (ED431G 2023/07), ‘ERDF A way of making Europe’ and Norwegian Research Council RCN, project 315287 to AMW.","OA_place":"publisher","article_type":"original","department":[{"_id":"NiBa"}],"day":"01","date_published":"2025-11-01T00:00:00Z","publication_identifier":{"issn":["0962-1083"],"eissn":["1365-294X"]},"OA_type":"hybrid","oa":1,"external_id":{"isi":["001538172800001"]},"date_created":"2025-08-03T22:01:31Z","oa_version":"Published Version","article_number":"e70025","_id":"20102","publication":"Molecular Ecology","file":[{"content_type":"application/pdf","success":1,"date_updated":"2025-12-30T09:25:17Z","access_level":"open_access","file_id":"20906","creator":"dernst","file_name":"2025_MolecEcology_Raffini.pdf","relation":"main_file","file_size":2767745,"checksum":"ec01edda64cfbc6cbc8adf300f719644","date_created":"2025-12-30T09:25:17Z"}],"quality_controlled":"1","ddc":["570"],"year":"2025","language":[{"iso":"eng"}],"volume":34,"article_processing_charge":"Yes (in subscription journal)","isi":1,"month":"11","file_date_updated":"2025-12-30T09:25:17Z","issue":"21","scopus_import":"1","doi":"10.1111/mec.70025","citation":{"ama":"Raffini F, De Jode A, Johannesson K, et al. Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail. <i>Molecular Ecology</i>. 2025;34(21). doi:<a href=\"https://doi.org/10.1111/mec.70025\">10.1111/mec.70025</a>","short":"F. Raffini, A. De Jode, K. Johannesson, R. Faria, Z.B. Zagrodzka, A.M. Westram, J. Galindo, E. Rolán-Alvarez, R.K. Butlin, Molecular Ecology 34 (2025).","chicago":"Raffini, Francesca, Aurélien De Jode, Kerstin Johannesson, Rui Faria, Zuzanna B. Zagrodzka, Anja M Westram, Juan Galindo, Emilio Rolán-Alvarez, and Roger K. Butlin. “Phenotypic Divergence and Genomic Architecture between Parallel Ecotypes at Two Different Points on the Speciation Continuum in a Marine Snail.” <i>Molecular Ecology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/mec.70025\">https://doi.org/10.1111/mec.70025</a>.","ista":"Raffini F, De Jode A, Johannesson K, Faria R, Zagrodzka ZB, Westram AM, Galindo J, Rolán-Alvarez E, Butlin RK. 2025. Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail. Molecular Ecology. 34(21), e70025.","ieee":"F. Raffini <i>et al.</i>, “Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail,” <i>Molecular Ecology</i>, vol. 34, no. 21. Wiley, 2025.","apa":"Raffini, F., De Jode, A., Johannesson, K., Faria, R., Zagrodzka, Z. B., Westram, A. M., … Butlin, R. K. (2025). Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail. <i>Molecular Ecology</i>. Wiley. <a href=\"https://doi.org/10.1111/mec.70025\">https://doi.org/10.1111/mec.70025</a>","mla":"Raffini, Francesca, et al. “Phenotypic Divergence and Genomic Architecture between Parallel Ecotypes at Two Different Points on the Speciation Continuum in a Marine Snail.” <i>Molecular Ecology</i>, vol. 34, no. 21, e70025, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/mec.70025\">10.1111/mec.70025</a>."},"abstract":[{"text":"Speciation is rarely observable directly. A way forward is to compare pairs of ecotypes that evolved in parallel in similar contexts but have reached different degrees of reproductive isolation. Such comparisons are possible in the marine snail Littorina saxatilis by contrasting barriers to gene flow between parallel ecotypes in Spain and Sweden. In both countries, divergent ecotypes have evolved to withstand either crab predation or wave action. Here, we explore transects spanning contact zones between the Crab and the Wave ecotypes using low-coverage whole-genome sequencing, morphological and behavioural traits. Despite parallel phenotypic divergence, distinct patterns of differentiation between the ecotypes emerged: a continuous cline in Sweden indicating a weak barrier to gene flow, but two highly genetically and phenotypically divergent, and partly spatially overlapping clusters in Spain suggesting a much stronger barrier to gene flow. The absence of Spanish early-generation hybrids supported strong isolation, but a low level of gene flow is evident from molecular data. In both countries, highly differentiated loci were located in both shared and country-specific chromosomal inversions but were also present in collinear regions. Despite being considered the same species and showing similar levels of phenotypic divergence, the Spanish ecotypes are much closer to full reproductive isolation than the Swedish ones. Barriers to gene flow of very different strengths between ecotypes within the same species might be explained by dissimilarities in the spatial arrangement of habitats, the selection gradients or the ages of the systems.","lang":"eng"}],"publication_status":"published","publisher":"Wiley","type":"journal_article","has_accepted_license":"1","intvolume":"        34","PlanS_conform":"1"},{"day":"27","department":[{"_id":"AlBr"}],"month":"06","OA_place":"repository","license":"https://creativecommons.org/publicdomain/zero/1.0/","title":"Replication Data for: \"Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment\"","main_file_link":[{"url":"https://doi.org/10.7910/DVN/DYEBVM","open_access":"1"}],"author":[{"last_name":"Vedula","first_name":"Sanketh","full_name":"Vedula, Sanketh","id":"94f2fe44-70fa-11f0-b76b-92922c09452b"},{"first_name":"Alexander","last_name":"Bronstein","orcid":"0000-0001-9699-8730","full_name":"Bronstein, Alexander","id":"58f3726e-7cba-11ef-ad8b-e6e8cb3904e6"},{"first_name":"Ailie","last_name":"Marx","full_name":"Marx, Ailie"}],"article_processing_charge":"No","date_updated":"2025-11-27T14:09:58Z","tmp":{"legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png","name":"Creative Commons Public Domain Dedication (CC0 1.0)","short":"CC0 (1.0)"},"status":"public","ddc":["000"],"year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","type":"research_data_reference","_id":"20103","publisher":"Harvard Dataverse","date_created":"2025-08-04T06:18:55Z","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Official implementation, windowed MSAs, and the predictions as reported in the manuscript titled \"Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment\". (2025-06-27)"}],"oa":1,"citation":{"short":"S. Vedula, A.M. Bronstein, A. Marx, (2025).","ama":"Vedula S, Bronstein AM, Marx A. Replication Data for: “Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.” 2025. doi:<a href=\"https://doi.org/10.7910/DVN/DYEBVM\">10.7910/DVN/DYEBVM</a>","ista":"Vedula S, Bronstein AM, Marx A. 2025. Replication Data for: ‘Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment’, Harvard Dataverse, <a href=\"https://doi.org/10.7910/DVN/DYEBVM\">10.7910/DVN/DYEBVM</a>.","chicago":"Vedula, Sanketh, Alex M. Bronstein, and Ailie Marx. “Replication Data for: ‘Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.’” Harvard Dataverse, 2025. <a href=\"https://doi.org/10.7910/DVN/DYEBVM\">https://doi.org/10.7910/DVN/DYEBVM</a>.","ieee":"S. Vedula, A. M. Bronstein, and A. Marx, “Replication Data for: ‘Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.’” Harvard Dataverse, 2025.","mla":"Vedula, Sanketh, et al. <i>Replication Data for: “Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.”</i> Harvard Dataverse, 2025, doi:<a href=\"https://doi.org/10.7910/DVN/DYEBVM\">10.7910/DVN/DYEBVM</a>.","apa":"Vedula, S., Bronstein, A. M., &#38; Marx, A. (2025). Replication Data for: “Improving Prediction Accuracy in Chimeric Proteins with Windowed Multiple Sequence Alignment.” Harvard Dataverse. <a href=\"https://doi.org/10.7910/DVN/DYEBVM\">https://doi.org/10.7910/DVN/DYEBVM</a>"},"doi":"10.7910/DVN/DYEBVM","related_material":{"record":[{"relation":"used_for_analysis_in","id":"20100","status":"public"}]},"date_published":"2025-06-27T00:00:00Z"},{"type":"research_data_reference","_id":"20107","publisher":"Zenodo","corr_author":"1","project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"date_created":"2025-08-04T07:34:39Z","oa_version":"Published Version","has_accepted_license":"1","doi":"10.5281/ZENODO.13988679","OA_type":"green","related_material":{"record":[{"status":"public","id":"20098","relation":"used_in_publication"}]},"date_published":"2025-05-21T00:00:00Z","abstract":[{"text":"This repository contains the data and scripts required to reproduce the results of the manuscript \"Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages\" submitted to the Environmental Research Climate Journal (ERCL). ","lang":"eng"}],"oa":1,"citation":{"short":"Y.-L. Hwong, E. Byers, M. Werning, Y. Quilcaille, (2025).","ama":"Hwong Y-L, Byers E, Werning M, Quilcaille Y. Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages. 2025. doi:<a href=\"https://doi.org/10.5281/ZENODO.13988679\">10.5281/ZENODO.13988679</a>","chicago":"Hwong, Yi-Ling, Edward Byers, Michaela Werning, and Yann Quilcaille. “Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages.” Zenodo, 2025. <a href=\"https://doi.org/10.5281/ZENODO.13988679\">https://doi.org/10.5281/ZENODO.13988679</a>.","ieee":"Y.-L. Hwong, E. Byers, M. Werning, and Y. Quilcaille, “Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages.” Zenodo, 2025.","ista":"Hwong Y-L, Byers E, Werning M, Quilcaille Y. 2025. Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages, Zenodo, <a href=\"https://doi.org/10.5281/ZENODO.13988679\">10.5281/ZENODO.13988679</a>.","apa":"Hwong, Y.-L., Byers, E., Werning, M., &#38; Quilcaille, Y. (2025). Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages. Zenodo. <a href=\"https://doi.org/10.5281/ZENODO.13988679\">https://doi.org/10.5281/ZENODO.13988679</a>","mla":"Hwong, Yi-Ling, et al. <i>Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages</i>. Zenodo, 2025, doi:<a href=\"https://doi.org/10.5281/ZENODO.13988679\">10.5281/ZENODO.13988679</a>."},"author":[{"full_name":"Hwong, Yi-Ling","orcid":"0000-0001-9281-3479","last_name":"Hwong","first_name":"Yi-Ling","id":"1217aa61-4dd1-11ec-9ac3-f2ba3f17ee22"},{"first_name":"Edward","last_name":"Byers","full_name":"Byers, Edward"},{"full_name":"Werning, Michaela","first_name":"Michaela","last_name":"Werning"},{"full_name":"Quilcaille, Yann","last_name":"Quilcaille","first_name":"Yann"}],"main_file_link":[{"url":"https://doi.org/10.5281/zenodo.15409324","open_access":"1"}],"title":"Data - Sustainable Development Key to Limiting Climate Change-Driven Wildfire Damages","article_processing_charge":"No","ec_funded":1,"day":"21","department":[{"_id":"CaMu"}],"month":"05","OA_place":"repository","ddc":["550"],"year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-08-04T07:46:33Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"day":"24","department":[{"_id":"JiFr"}],"OA_place":"publisher","article_type":"original","acknowledgement":"The study was supported by the National Natural Science Foundation of China (NSFC; 32230011, 91954206, and 31721001). We thank Dr. Deli Lin (Shanghai Jiao Tong University) for kind help with the laser confocal microscope observation and the Arabidopsis Biological Resource Center (ABRC) for providing T-DNA insertional mutants.","author":[{"first_name":"Faqing","last_name":"Xu","full_name":"Xu, Faqing"},{"first_name":"Yongqiang","last_name":"Yu","full_name":"Yu, Yongqiang"},{"id":"56aad729-cca2-11ed-a45a-9b4138991a48","full_name":"Guan, Bin","first_name":"Bin","last_name":"Guan"},{"full_name":"Xu, Tongda","first_name":"Tongda","last_name":"Xu"},{"full_name":"Xu, Zhihong","last_name":"Xu","first_name":"Zhihong"},{"full_name":"Xue, Hongwei","first_name":"Hongwei","last_name":"Xue"}],"title":"Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis","tmp":{"short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"date_updated":"2025-09-30T14:13:45Z","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file":[{"file_name":"2025_CellReports_Xu.pdf","creator":"dernst","date_created":"2025-08-05T06:15:09Z","checksum":"3c43e040a4a7a65ec67ae1d2bb81261a","file_size":24178018,"relation":"main_file","access_level":"open_access","date_updated":"2025-08-05T06:15:09Z","content_type":"application/pdf","success":1,"file_id":"20120"}],"publication":"Cell Reports","pmid":1,"_id":"20116","oa_version":"Published Version","article_number":"116056","date_created":"2025-08-04T13:39:11Z","external_id":{"pmid":["40714631"],"isi":["001542038500001"]},"oa":1,"OA_type":"gold","publication_identifier":{"eissn":["2211-1247"]},"date_published":"2025-07-24T00:00:00Z","DOAJ_listed":"1","issue":"8","file_date_updated":"2025-08-05T06:15:09Z","month":"07","isi":1,"license":"https://creativecommons.org/licenses/by-nc/4.0/","article_processing_charge":"Yes","volume":44,"language":[{"iso":"eng"}],"ddc":["580"],"year":"2025","quality_controlled":"1","intvolume":"        44","has_accepted_license":"1","publisher":"Elsevier","type":"journal_article","publication_status":"published","abstract":[{"lang":"eng","text":"Auxin regulates various aspects of plant growth and development by modulating the transcription of target genes through the degradation of auxin/indole-3-acetic acid (Aux/IAA) repressors via the 26S proteasome. Proteasome regulator 1 (PTRE1), a positive regulator of proteasome activity, has been implicated in auxin-mediated proteasome suppression; however, the mechanism by which auxin modulates PTRE1 function remains unclear. Here, we demonstrate that auxin promotes the interaction between germin-like protein 1 (GLP1) and PTRE1, facilitating PTRE1 retention at the plasma membrane. The relocation of PTRE1 results in reduced nuclear 26S proteasome activity, and thus the attenuated Aux/IAA degradation and altered Aux/IAA homeostasis, ultimately resulting in suppressed auxin-mediated transcriptional regulation. Our findings uncover a previously uncharacterized regulatory axis in auxin signaling that controls Aux/IAA protein stability, functioning alongside the TIR1- and TRANSMEMBRANE KINASE 1 (TMK1)-mediated pathways, and highlight the coordination of auxin signaling from the cell surface to the nucleus via auxin-induced PTRE1 relocation, which fine-tunes Aux/IAA protein homeostasis and auxin responses."}],"citation":{"mla":"Xu, Faqing, et al. “Germin-like Protein 1 Interacts with Proteasome Regulator 1 to Regulate Auxin Signaling by Controlling Aux/IAA Homeostasis.” <i>Cell Reports</i>, vol. 44, no. 8, 116056, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116056\">10.1016/j.celrep.2025.116056</a>.","apa":"Xu, F., Yu, Y., Guan, B., Xu, T., Xu, Z., &#38; Xue, H. (2025). Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis. <i>Cell Reports</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.celrep.2025.116056\">https://doi.org/10.1016/j.celrep.2025.116056</a>","ieee":"F. Xu, Y. Yu, B. Guan, T. Xu, Z. Xu, and H. Xue, “Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis,” <i>Cell Reports</i>, vol. 44, no. 8. Elsevier, 2025.","ista":"Xu F, Yu Y, Guan B, Xu T, Xu Z, Xue H. 2025. Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis. Cell Reports. 44(8), 116056.","chicago":"Xu, Faqing, Yongqiang Yu, Bin Guan, Tongda Xu, Zhihong Xu, and Hongwei Xue. “Germin-like Protein 1 Interacts with Proteasome Regulator 1 to Regulate Auxin Signaling by Controlling Aux/IAA Homeostasis.” <i>Cell Reports</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.celrep.2025.116056\">https://doi.org/10.1016/j.celrep.2025.116056</a>.","ama":"Xu F, Yu Y, Guan B, Xu T, Xu Z, Xue H. Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis. <i>Cell Reports</i>. 2025;44(8). doi:<a href=\"https://doi.org/10.1016/j.celrep.2025.116056\">10.1016/j.celrep.2025.116056</a>","short":"F. Xu, Y. Yu, B. Guan, T. Xu, Z. Xu, H. Xue, Cell Reports 44 (2025)."},"doi":"10.1016/j.celrep.2025.116056","scopus_import":"1"},{"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","status":"public","date_updated":"2026-04-07T11:49:34Z","author":[{"first_name":"Yiqun","last_name":"Wang","full_name":"Wang, Yiqun","id":"82F537F2-B517-11E9-84D7-6433E6697425"}],"title":"The role of dynamin related protein 2A in cytokinin regulated plant growth and development","alternative_title":["ISTA Thesis"],"degree_awarded":"PhD","acknowledgement":"I would also like to acknowledge the invaluable assistance provided by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility. The technical support and\r\nresources offered by these facilities were indispensable to the successful completion of my\r\nexperiments.","OA_place":"publisher","day":"04","department":[{"_id":"GradSch"},{"_id":"EvBe"}],"date_published":"2025-08-04T00:00:00Z","publication_identifier":{"issn":["2663-337X"]},"date_created":"2025-08-04T15:24:21Z","oa_version":"Published Version","_id":"20117","file":[{"checksum":"36b87c17d12c7bf5955d6d812acb8d77","date_created":"2025-08-22T08:22:10Z","file_size":25798848,"relation":"source_file","file_name":"2025_Wang_Yiqun_Thesis.docx","creator":"yiqwang","file_id":"20209","access_level":"closed","date_updated":"2025-08-22T08:53:46Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document"},{"creator":"yiqwang","embargo_to":"open_access","file_name":"2025_Wang_Yiqun_Thesis.pdf","embargo":"2026-09-03","relation":"main_file","file_size":12628313,"date_created":"2025-08-22T10:32:30Z","checksum":"8d7a2383f66377da675d379ec30ea0fe","content_type":"application/pdf","date_updated":"2025-09-03T09:36:52Z","access_level":"closed","file_id":"20211"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"ddc":["580"],"year":"2025","language":[{"iso":"eng"}],"article_processing_charge":"No","month":"08","file_date_updated":"2025-09-03T09:36:52Z","page":"108","doi":"10.15479/AT-ISTA-20117","related_material":{"record":[{"id":"18063","relation":"part_of_dissertation","status":"public"}]},"citation":{"mla":"Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>.","apa":"Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated plant growth and development</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>","short":"Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development, Institute of Science and Technology Austria, 2025.","ama":"Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20117\">10.15479/AT-ISTA-20117</a>","chicago":"Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant Growth and Development.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20117\">https://doi.org/10.15479/AT-ISTA-20117</a>.","ieee":"Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant growth and development,” Institute of Science and Technology Austria, 2025.","ista":"Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated plant growth and development. Institute of Science and Technology Austria."},"publication_status":"published","publisher":"Institute of Science and Technology Austria","corr_author":"1","type":"dissertation","supervisor":[{"full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}],"has_accepted_license":"1"}]