[{"ddc":["004","005"],"fulldoi":"https://doi.org/10.1007/978-3-642-34961-4_40","publist_id":"3730","intvolume":"      7658","doi":"10.1007/978-3-642-34961-4_40","_id":"2974","status":"public","author":[{"last_name":"Jain","full_name":"Jain, Abhishek","first_name":"Abhishek"},{"full_name":"Krenn, Stephan","first_name":"Stephan","last_name":"Krenn","id":"329FCCF0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2835-9093"},{"full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z","last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654"},{"full_name":"Tentes, Aris","first_name":"Aris","last_name":"Tentes"}],"oa_version":"Submitted Version","scopus_import":1,"conference":{"start_date":"2012-12-02","name":"ASIACRYPT: Theory and Application of Cryptology and Information Security","location":"Beijing, China","end_date":"2012-12-06"},"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","department":[{"_id":"KrPi"}],"file_date_updated":"2020-07-14T12:45:58Z","day":"01","language":[{"iso":"eng"}],"project":[{"_id":"258C570E-B435-11E9-9278-68D0E5697425","name":"Provable Security for Physical Cryptography","call_identifier":"FP7","grant_number":"259668"}],"editor":[{"last_name":"Wang","full_name":"Wang, Xiaoyun","first_name":"Xiaoyun"},{"full_name":"Sako, Kazue","first_name":"Kazue","last_name":"Sako"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"We construct a perfectly binding string commitment scheme whose security is based on the learning parity with noise (LPN) assumption, or equivalently, the hardness of decoding random linear codes. Our scheme not only allows for a simple and efficient zero-knowledge proof of knowledge for committed values (essentially a Σ-protocol), but also for such proofs showing any kind of relation amongst committed values, i.e. proving that messages m_0,...,m_u, are such that m_0=C(m_1,...,m_u) for any circuit C.\r\n\r\nTo get soundness which is exponentially small in a security parameter t, and when the zero-knowledge property relies on the LPN problem with secrets of length l, our 3 round protocol has communication complexity O(t|C|l log(l)) and computational complexity of O(t|C|l) bit operations. The hidden constants are small, and the computation consists mostly of computing inner products of bit-vectors.","lang":"eng"}],"date_published":"2012-12-01T00:00:00Z","title":"Commitments and efficient zero knowledge proofs from learning parity with noise","month":"12","citation":{"mla":"Jain, Abhishek, et al. <i>Commitments and Efficient Zero Knowledge Proofs from Learning Parity with Noise</i>. Edited by Xiaoyun Wang and Kazue Sako, vol. 7658, Springer, 2012, pp. 663–80, doi:<a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">10.1007/978-3-642-34961-4_40</a>.","ista":"Jain A, Krenn S, Pietrzak KZ, Tentes A. 2012. Commitments and efficient zero knowledge proofs from learning parity with noise. ASIACRYPT: Theory and Application of Cryptology and Information Security, LNCS, vol. 7658, 663–680.","ama":"Jain A, Krenn S, Pietrzak KZ, Tentes A. Commitments and efficient zero knowledge proofs from learning parity with noise. In: Wang X, Sako K, eds. Vol 7658. Springer; 2012:663-680. doi:<a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">10.1007/978-3-642-34961-4_40</a>","chicago":"Jain, Abhishek, Stephan Krenn, Krzysztof Z Pietrzak, and Aris Tentes. “Commitments and Efficient Zero Knowledge Proofs from Learning Parity with Noise.” edited by Xiaoyun Wang and Kazue Sako, 7658:663–80. Springer, 2012. <a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">https://doi.org/10.1007/978-3-642-34961-4_40</a>.","ieee":"A. Jain, S. Krenn, K. Z. Pietrzak, and A. Tentes, “Commitments and efficient zero knowledge proofs from learning parity with noise,” presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Beijing, China, 2012, vol. 7658, pp. 663–680.","short":"A. Jain, S. Krenn, K.Z. Pietrzak, A. Tentes, in:, X. Wang, K. Sako (Eds.), Springer, 2012, pp. 663–680.","apa":"Jain, A., Krenn, S., Pietrzak, K. Z., &#38; Tentes, A. (2012). Commitments and efficient zero knowledge proofs from learning parity with noise. In X. Wang &#38; K. Sako (Eds.) (Vol. 7658, pp. 663–680). Presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Beijing, China: Springer. <a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">https://doi.org/10.1007/978-3-642-34961-4_40</a>"},"year":"2012","page":"663 - 680","type":"conference","publisher":"Springer","license":"https://creativecommons.org/licenses/by/4.0/","date_updated":"2021-01-12T07:40:11Z","file":[{"access_level":"open_access","file_size":482570,"content_type":"application/pdf","checksum":"ab879537385efc4cb4203e7ef0fea17b","relation":"main_file","creator":"system","file_name":"IST-2016-721-v1+1_513.pdf","file_id":"5048","date_updated":"2020-07-14T12:45:58Z","date_created":"2018-12-12T10:14:00Z"}],"pubrep_id":"721","oa":1,"ec_funded":1,"alternative_title":["LNCS"],"volume":7658,"has_accepted_license":"1","acknowledgement":"We are grateful to Petros Mol for helpful discussions on the reduction for the hardness of the xLPN problem.\r\n","date_created":"2018-12-11T12:00:38Z"},{"_id":"12198","quality_controlled":"1","status":"public","author":[{"first_name":"Christian A.","full_name":"Ibarra, Christian A.","last_name":"Ibarra"},{"full_name":"Feng, Xiaoqi","first_name":"Xiaoqi","last_name":"Feng","orcid":"0000-0002-4008-1234","id":"e0164712-22ee-11ed-b12a-d80fcdf35958"},{"first_name":"Vera K.","full_name":"Schoft, Vera K.","last_name":"Schoft"},{"last_name":"Hsieh","full_name":"Hsieh, Tzung-Fu","first_name":"Tzung-Fu"},{"last_name":"Uzawa","first_name":"Rie","full_name":"Uzawa, Rie"},{"full_name":"Rodrigues, Jessica A.","first_name":"Jessica A.","last_name":"Rodrigues"},{"full_name":"Zemach, Assaf","first_name":"Assaf","last_name":"Zemach"},{"full_name":"Chumak, Nina","first_name":"Nina","last_name":"Chumak"},{"first_name":"Adriana","full_name":"Machlicova, Adriana","last_name":"Machlicova"},{"last_name":"Nishimura","first_name":"Toshiro","full_name":"Nishimura, Toshiro"},{"last_name":"Rojas","first_name":"Denisse","full_name":"Rojas, Denisse"},{"full_name":"Fischer, Robert L.","first_name":"Robert L.","last_name":"Fischer"},{"first_name":"Hisashi","full_name":"Tamaru, Hisashi","last_name":"Tamaru"},{"first_name":"Daniel","full_name":"Zilberman, Daniel","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1","orcid":"0000-0002-0123-8649","last_name":"Zilberman"}],"intvolume":"       337","doi":"10.1126/science.1224839","oa_version":"Published Version","fulldoi":"https://doi.org/10.1126/science.1224839","external_id":{"pmid":["22984074"]},"article_processing_charge":"No","scopus_import":"1","language":[{"iso":"eng"}],"day":"14","publication_status":"published","department":[{"_id":"XiFe"}],"year":"2012","date_published":"2012-09-14T00:00:00Z","abstract":[{"lang":"eng","text":"The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes DNA demethylation before fertilization, but the targeting preferences, mechanism, and biological significance of this process remain unclear. Here, we show that active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for all of the demethylation in the central cell and preferentially targets small, AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation of similar sequences, and lack of DEMETER in vegetative cells causes reduced small RNA–directed DNA methylation of transposons in sperm. Our results demonstrate that demethylation in companion cells reinforces transposon methylation in plant gametes and likely contributes to stable silencing of transposable elements across generations."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes","citation":{"ista":"Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A, Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman D. 2012. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. 337(6100), 1360–1364.","mla":"Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>, vol. 337, no. 6100, American Association for the Advancement of Science, 2012, pp. 1360–64, doi:<a href=\"https://doi.org/10.1126/science.1224839\">10.1126/science.1224839</a>.","chicago":"Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>. American Association for the Advancement of Science, 2012. <a href=\"https://doi.org/10.1126/science.1224839\">https://doi.org/10.1126/science.1224839</a>.","ama":"Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. <i>Science</i>. 2012;337(6100):1360-1364. doi:<a href=\"https://doi.org/10.1126/science.1224839\">10.1126/science.1224839</a>","short":"C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues, A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H. Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.","ieee":"C. A. Ibarra <i>et al.</i>, “Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes,” <i>Science</i>, vol. 337, no. 6100. American Association for the Advancement of Science, pp. 1360–1364, 2012.","apa":"Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues, J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1224839\">https://doi.org/10.1126/science.1224839</a>"},"month":"09","page":"1360-1364","keyword":["Multidisciplinary"],"publisher":"American Association for the Advancement of Science","type":"journal_article","pmid":1,"publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"article_type":"original","date_updated":"2025-01-14T12:37:28Z","extern":"1","oa":1,"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/","open_access":"1"}],"issue":"6100","date_created":"2023-01-16T09:21:24Z","volume":337,"acknowledgement":"We thank S. Harmer for assistance with the analysis of histone modifications, the BioOptics team at the Vienna Biocenter Campus for sorting sperm and vegetative cell nuclei, K. Slotkin for the LAT52p-amiRNA=GFP plasmid, and G. Drews for the DD45p-GFP transgenic line. This work was partially funded by an NIH grant (GM69415) to R.L.F., NSF grants (MCB-0918821 and IOS-1025890) to R.L.F. and D.Z., a Young Investigator Grant from the Arnold and Mabel Beckman Foundation to D.Z., an Austrian Science Fund (FWF) grant P21389-B03 to H.T., a Ruth L. Kirschstein NIH Predoctoral Fellowship (GM093633) to C.A.I., a Fulbright Scholarship to J.A.R., a fellowship from the Jane Coffin Childs Memorial Fund to A.Z., and a Robert and Colleen Haas Scholarship to D.R. Sequencing data are deposited in GEO (GSE38935).","publication":"Science"},{"publication_status":"published","day":"01","language":[{"iso":"eng"}],"date_published":"2012-03-01T00:00:00Z","abstract":[{"lang":"eng","text":"In the Dry Andes of central Chile, summer water resources originate mostly from snowmelt and ice melt. We use the physically based, spatially distributed hydrological model TOPKAPI to study the exchange between glaciers and climate in the upper Aconcagua River Basin during the summer season and identify the model parameters that are robust and transferable and those that are more dependent on calibration. TOPKAPI has recently been adapted to incorporate an enhanced temperature index approach for snow and ice melting. We suggest a calibration procedure that allows calibration of parameters in three steps by separating parameters governing distinct processes. We evaluate the parameters' transferability in time and in space by applying the model at two spatial scales. TOPKAPI's ability to simulate the relevant processes is tested against meteorological, ablation, and glacier runoff data measured on Juncal Norte Glacier during two glacier ablation seasons. The model was applied successfully to the climatic setting of the Dry Andes once its parameters were recalibrated. We found a clear distinction between parameters that are stable in time and those that need recalibration. The parameters of the melt model are transferable from one season to the other, while the parameters governing the extrapolation of meteorological input data and the routing of glacier meltwater need recalibration from one season to the other. Sensitivity analysis revealed that the model is most sensitive to the temperature lapse rate governing the extrapolation of air temperature from point measurements to the glacier scale and to the melt parameter that multiplies the shortwave radiation balance."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"03","citation":{"apa":"Ragettli, S., &#38; Pellicciotti, F. (2012). Calibration of a physically based, spatially distributed hydrological model in a glacierized basin: On the use of knowledge from glaciometeorological processes to constrain model parameters. <i>Water Resources Research</i>. American Geophysical Union. <a href=\"https://doi.org/10.1029/2011wr010559\">https://doi.org/10.1029/2011wr010559</a>","ieee":"S. Ragettli and F. Pellicciotti, “Calibration of a physically based, spatially distributed hydrological model in a glacierized basin: On the use of knowledge from glaciometeorological processes to constrain model parameters,” <i>Water Resources Research</i>, vol. 48, no. 3. American Geophysical Union, 2012.","short":"S. Ragettli, F. Pellicciotti, Water Resources Research 48 (2012).","chicago":"Ragettli, S., and Francesca Pellicciotti. “Calibration of a Physically Based, Spatially Distributed Hydrological Model in a Glacierized Basin: On the Use of Knowledge from Glaciometeorological Processes to Constrain Model Parameters.” <i>Water Resources Research</i>. American Geophysical Union, 2012. <a href=\"https://doi.org/10.1029/2011wr010559\">https://doi.org/10.1029/2011wr010559</a>.","ama":"Ragettli S, Pellicciotti F. Calibration of a physically based, spatially distributed hydrological model in a glacierized basin: On the use of knowledge from glaciometeorological processes to constrain model parameters. <i>Water Resources Research</i>. 2012;48(3). doi:<a href=\"https://doi.org/10.1029/2011wr010559\">10.1029/2011wr010559</a>","mla":"Ragettli, S., and Francesca Pellicciotti. “Calibration of a Physically Based, Spatially Distributed Hydrological Model in a Glacierized Basin: On the Use of Knowledge from Glaciometeorological Processes to Constrain Model Parameters.” <i>Water Resources Research</i>, vol. 48, no. 3, W03509, American Geophysical Union, 2012, doi:<a href=\"https://doi.org/10.1029/2011wr010559\">10.1029/2011wr010559</a>.","ista":"Ragettli S, Pellicciotti F. 2012. Calibration of a physically based, spatially distributed hydrological model in a glacierized basin: On the use of knowledge from glaciometeorological processes to constrain model parameters. Water Resources Research. 48(3), W03509."},"title":"Calibration of a physically based, spatially distributed hydrological model in a glacierized basin: On the use of knowledge from glaciometeorological processes to constrain model parameters","year":"2012","fulldoi":"https://doi.org/10.1029/2011wr010559","status":"public","_id":"12644","quality_controlled":"1","author":[{"last_name":"Ragettli","first_name":"S.","full_name":"Ragettli, S."},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca"}],"intvolume":"        48","doi":"10.1029/2011wr010559","oa_version":"Published Version","article_processing_charge":"No","scopus_import":"1","article_number":"W03509","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1029/2011WR010559"}],"extern":"1","oa":1,"volume":48,"publication":"Water Resources Research","issue":"3","date_created":"2023-02-20T08:17:39Z","publication_identifier":{"issn":["0043-1397"]},"publisher":"American Geophysical Union","type":"journal_article","date_updated":"2023-02-21T09:38:36Z","article_type":"original"},{"oa_version":"Published Version","intvolume":"        32","doi":"10.1659/mrd-journal-d-11-00092.1","quality_controlled":"1","_id":"12646","status":"public","author":[{"last_name":"Pellicciotti","orcid":"0000-0002-5554-8087","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca"},{"first_name":"Cyrill","full_name":"Buergi, Cyrill","last_name":"Buergi"},{"last_name":"Immerzeel","full_name":"Immerzeel, Walter Willem","first_name":"Walter Willem"},{"first_name":"Markus","full_name":"Konz, Markus","last_name":"Konz"},{"full_name":"Shrestha, Arun B.","first_name":"Arun B.","last_name":"Shrestha"}],"fulldoi":"https://doi.org/10.1659/mrd-journal-d-11-00092.1","scopus_import":"1","article_processing_charge":"No","day":"01","language":[{"iso":"eng"}],"publication_status":"published","year":"2012","title":"Challenges and uncertainties in hydrological modeling of remote Hindu Kush–Karakoram–Himalayan (HKH) basins: Suggestions for calibration strategies","month":"02","citation":{"ista":"Pellicciotti F, Buergi C, Immerzeel WW, Konz M, Shrestha AB. 2012. Challenges and uncertainties in hydrological modeling of remote Hindu Kush–Karakoram–Himalayan (HKH) basins: Suggestions for calibration strategies. Mountain Research and Development. 32(1), 39–50.","mla":"Pellicciotti, Francesca, et al. “Challenges and Uncertainties in Hydrological Modeling of Remote Hindu Kush–Karakoram–Himalayan (HKH) Basins: Suggestions for Calibration Strategies.” <i>Mountain Research and Development</i>, vol. 32, no. 1, International Mountain Society, 2012, pp. 39–50, doi:<a href=\"https://doi.org/10.1659/mrd-journal-d-11-00092.1\">10.1659/mrd-journal-d-11-00092.1</a>.","apa":"Pellicciotti, F., Buergi, C., Immerzeel, W. W., Konz, M., &#38; Shrestha, A. B. (2012). Challenges and uncertainties in hydrological modeling of remote Hindu Kush–Karakoram–Himalayan (HKH) basins: Suggestions for calibration strategies. <i>Mountain Research and Development</i>. International Mountain Society. <a href=\"https://doi.org/10.1659/mrd-journal-d-11-00092.1\">https://doi.org/10.1659/mrd-journal-d-11-00092.1</a>","ieee":"F. Pellicciotti, C. Buergi, W. W. Immerzeel, M. Konz, and A. B. Shrestha, “Challenges and uncertainties in hydrological modeling of remote Hindu Kush–Karakoram–Himalayan (HKH) basins: Suggestions for calibration strategies,” <i>Mountain Research and Development</i>, vol. 32, no. 1. International Mountain Society, pp. 39–50, 2012.","short":"F. Pellicciotti, C. Buergi, W.W. Immerzeel, M. Konz, A.B. Shrestha, Mountain Research and Development 32 (2012) 39–50.","ama":"Pellicciotti F, Buergi C, Immerzeel WW, Konz M, Shrestha AB. Challenges and uncertainties in hydrological modeling of remote Hindu Kush–Karakoram–Himalayan (HKH) basins: Suggestions for calibration strategies. <i>Mountain Research and Development</i>. 2012;32(1):39-50. doi:<a href=\"https://doi.org/10.1659/mrd-journal-d-11-00092.1\">10.1659/mrd-journal-d-11-00092.1</a>","chicago":"Pellicciotti, Francesca, Cyrill Buergi, Walter Willem Immerzeel, Markus Konz, and Arun B. Shrestha. “Challenges and Uncertainties in Hydrological Modeling of Remote Hindu Kush–Karakoram–Himalayan (HKH) Basins: Suggestions for Calibration Strategies.” <i>Mountain Research and Development</i>. International Mountain Society, 2012. <a href=\"https://doi.org/10.1659/mrd-journal-d-11-00092.1\">https://doi.org/10.1659/mrd-journal-d-11-00092.1</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2012-02-01T00:00:00Z","abstract":[{"lang":"eng","text":"Assessment of water resources from remote mountainous catchments plays a crucial role for the development of rural areas in or in the vicinity of mountain ranges. The scarcity of data, however, prevents the application of standard approaches that are based on data-driven models. The Hindu Kush–Karakoram–Himalaya mountain range is a crucial area in terms of water resources, but our understanding of the response of its high-elevation catchments to a changing climate is hindered by lack of hydro-meteorological and cryospheric data. Hydrological modeling is challenging here because internal inconsistencies—such as an underestimation of precipitation input that can be compensated for by an overestimation of meltwater—might be hidden due to the complexity of feedback mechanisms that govern melt and runoff generation in such basins. Data scarcity adds to this difficulty by preventing the application of systematic calibration procedures that would allow identification of the parameter set that could guarantee internal consistency in the simulation of the single hydrological components. In this work, we use simulations from the Hunza River Basin in the Karakoram region obtained with the hydrological model TOPKAPI to quantify the predictive power of discharge and snow-cover data sets, as well as the combination of both. We also show that short-term measurements of meteorological variables such as radiative fluxes, wind speed, relative humidity, and air temperature from glacio-meteorological experiments are crucial for a correct parameterization of surface melt processes. They enable detailed simulations of the energy fluxes governing glacier–atmosphere interaction and the resulting ablation through energy-balance modeling. These simulations are used to derive calibrated parameters for the simplified snow and glacier routines in TOPKAPI. We demonstrate that such parameters are stable in space and time in similar climatic regions, thus reducing the number of parameters requiring calibration."}],"type":"journal_article","publisher":"International Mountain Society","page":"39-50","publication_identifier":{"eissn":["1994-7151"],"issn":["0276-4741"]},"article_type":"original","date_updated":"2024-10-14T12:01:31Z","oa":1,"extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1659/MRD-JOURNAL-D-11-00092.1"}],"date_created":"2023-02-20T08:17:47Z","issue":"1","publication":"Mountain Research and Development","volume":32},{"article_processing_charge":"No","scopus_import":"1","fulldoi":"https://doi.org/10.1659/mrd-journal-d-11-00097.1","intvolume":"        32","doi":"10.1659/mrd-journal-d-11-00097.1","_id":"12647","author":[{"first_name":"Walter Willem","full_name":"Immerzeel, Walter Willem","last_name":"Immerzeel"},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca"},{"full_name":"Shrestha, Arun B.","first_name":"Arun B.","last_name":"Shrestha"}],"status":"public","quality_controlled":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Accurate quantification of the spatial distribution of precipitation in mountain regions is crucial for assessments of water resources and for the understanding of high-altitude hydrology, yet it is one of the largest unknowns due to the lack of high-altitude observations. The Hunza basin in Pakistan contains very large glacier systems, which, given the melt, cannot persist unless precipitation (snow input) is much higher than what is observed at the meteorological stations, mostly located in mountain valleys. Several studies, therefore, suggest strong positive vertical precipitation lapse rates; in the present study, we quantify this lapse rate by using glaciers as a proxy. We assume a neutral mass balance for the glaciers for the period from 2001 to 2003, and we inversely model the precipitation lapse by balancing the total accumulation in the catchment area and the ablation over the glacier area for the 50 largest glacier systems in the Hunza basin in the Karakoram. Our results reveal a vertical precipitation lapse rate that equals 0.21 ± 0.12% m−1, with a maximum precipitation at an elevation of 5500 masl. We showed that the total annual basin precipitation (828 mm) is 260% higher than what is estimated based on interpolated observations (319 mm); this has major consequences for hydrological modeling and water resource assessments in general. Our results were validated by using previously published studies on individual glaciers as well as the water balance of the Hunza basin. The approach is more widely applicable in mountain ranges where precipitation measurements at high altitude are lacking."}],"date_published":"2012-02-01T00:00:00Z","title":"Glaciers as a proxy to quantify the spatial distribution of precipitation in the Hunza basin","citation":{"ista":"Immerzeel WW, Pellicciotti F, Shrestha AB. 2012. Glaciers as a proxy to quantify the spatial distribution of precipitation in the Hunza basin. Mountain Research and Development. 32(1), 30–38.","mla":"Immerzeel, Walter Willem, et al. “Glaciers as a Proxy to Quantify the Spatial Distribution of Precipitation in the Hunza Basin.” <i>Mountain Research and Development</i>, vol. 32, no. 1, International Mountain Society, 2012, pp. 30–38, doi:<a href=\"https://doi.org/10.1659/mrd-journal-d-11-00097.1\">10.1659/mrd-journal-d-11-00097.1</a>.","ieee":"W. W. Immerzeel, F. Pellicciotti, and A. B. Shrestha, “Glaciers as a proxy to quantify the spatial distribution of precipitation in the Hunza basin,” <i>Mountain Research and Development</i>, vol. 32, no. 1. International Mountain Society, pp. 30–38, 2012.","apa":"Immerzeel, W. W., Pellicciotti, F., &#38; Shrestha, A. B. (2012). Glaciers as a proxy to quantify the spatial distribution of precipitation in the Hunza basin. <i>Mountain Research and Development</i>. International Mountain Society. <a href=\"https://doi.org/10.1659/mrd-journal-d-11-00097.1\">https://doi.org/10.1659/mrd-journal-d-11-00097.1</a>","short":"W.W. Immerzeel, F. Pellicciotti, A.B. Shrestha, Mountain Research and Development 32 (2012) 30–38.","ama":"Immerzeel WW, Pellicciotti F, Shrestha AB. Glaciers as a proxy to quantify the spatial distribution of precipitation in the Hunza basin. <i>Mountain Research and Development</i>. 2012;32(1):30-38. doi:<a href=\"https://doi.org/10.1659/mrd-journal-d-11-00097.1\">10.1659/mrd-journal-d-11-00097.1</a>","chicago":"Immerzeel, Walter Willem, Francesca Pellicciotti, and Arun B. Shrestha. “Glaciers as a Proxy to Quantify the Spatial Distribution of Precipitation in the Hunza Basin.” <i>Mountain Research and Development</i>. International Mountain Society, 2012. <a href=\"https://doi.org/10.1659/mrd-journal-d-11-00097.1\">https://doi.org/10.1659/mrd-journal-d-11-00097.1</a>."},"month":"02","year":"2012","publication_status":"published","language":[{"iso":"eng"}],"day":"01","date_updated":"2023-02-21T08:56:29Z","article_type":"original","publication_identifier":{"issn":["0276-4741"],"eissn":["1994-7151"]},"page":"30-38","keyword":["General Environmental Science","Development","Environmental Chemistry"],"type":"journal_article","publisher":"International Mountain Society","volume":32,"publication":"Mountain Research and Development","date_created":"2023-02-20T08:17:52Z","issue":"1","main_file_link":[{"url":"https://doi.org/10.1659/MRD-JOURNAL-D-11-00097.1","open_access":"1"}],"extern":"1","oa":1},{"date_created":"2023-02-20T08:17:57Z","issue":"D18","publication":"Journal of Geophysical Research: Atmospheres","volume":117,"oa":1,"extern":"1","main_file_link":[{"url":"https://doi.org/10.1029/2012JD017795","open_access":"1"}],"article_type":"original","date_updated":"2023-02-20T10:57:31Z","type":"journal_article","publisher":"American Geophysical Union","keyword":["Paleontology","Space and Planetary Science","Earth and Planetary Sciences (miscellaneous)","Atmospheric Science","Earth-Surface Processes","Geochemistry and Petrology","Soil Science","Water Science and Technology","Ecology","Aquatic Science","Forestry","Oceanography","Geophysics"],"publication_identifier":{"issn":["0148-0227"]},"year":"2012","citation":{"mla":"Reid, T. D., et al. “Including Debris Cover Effects in a Distributed Model of Glacier Ablation.” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 117, no. D18, D18105, American Geophysical Union, 2012, doi:<a href=\"https://doi.org/10.1029/2012jd017795\">10.1029/2012jd017795</a>.","ista":"Reid TD, Carenzo M, Pellicciotti F, Brock BW. 2012. Including debris cover effects in a distributed model of glacier ablation. Journal of Geophysical Research: Atmospheres. 117(D18), D18105.","apa":"Reid, T. D., Carenzo, M., Pellicciotti, F., &#38; Brock, B. W. (2012). Including debris cover effects in a distributed model of glacier ablation. <i>Journal of Geophysical Research: Atmospheres</i>. American Geophysical Union. <a href=\"https://doi.org/10.1029/2012jd017795\">https://doi.org/10.1029/2012jd017795</a>","short":"T.D. Reid, M. Carenzo, F. Pellicciotti, B.W. Brock, Journal of Geophysical Research: Atmospheres 117 (2012).","ieee":"T. D. Reid, M. Carenzo, F. Pellicciotti, and B. W. Brock, “Including debris cover effects in a distributed model of glacier ablation,” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 117, no. D18. American Geophysical Union, 2012.","chicago":"Reid, T. D., M. Carenzo, Francesca Pellicciotti, and B. W. Brock. “Including Debris Cover Effects in a Distributed Model of Glacier Ablation.” <i>Journal of Geophysical Research: Atmospheres</i>. American Geophysical Union, 2012. <a href=\"https://doi.org/10.1029/2012jd017795\">https://doi.org/10.1029/2012jd017795</a>.","ama":"Reid TD, Carenzo M, Pellicciotti F, Brock BW. Including debris cover effects in a distributed model of glacier ablation. <i>Journal of Geophysical Research: Atmospheres</i>. 2012;117(D18). doi:<a href=\"https://doi.org/10.1029/2012jd017795\">10.1029/2012jd017795</a>"},"title":"Including debris cover effects in a distributed model of glacier ablation","month":"09","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Distributed glacier melt models generally assume that the glacier surface consists of bare exposed ice and snow. In reality, many glaciers are wholly or partially covered in layers of debris that tend to suppress ablation rates. In this paper, an existing physically based point model for the ablation of debris-covered ice is incorporated in a distributed melt model and applied to Haut Glacier d'Arolla, Switzerland, which has three large patches of debris cover on its surface. The model is based on a 10 m resolution digital elevation model (DEM) of the area; each glacier pixel in the DEM is defined as either bare or debris-covered ice, and may be covered in snow that must be melted off before ice ablation is assumed to occur. Each debris-covered pixel is assigned a debris thickness value using probability distributions based on over 1000 manual thickness measurements. Locally observed meteorological data are used to run energy balance calculations in every pixel, using an approach suitable for snow, bare ice or debris-covered ice as appropriate. The use of the debris model significantly reduces the total ablation in the debris-covered areas, however the precise reduction is sensitive to the temperature extrapolation used in the model distribution because air near the debris surface tends to be slightly warmer than over bare ice. Overall results suggest that the debris patches, which cover 10% of the glacierized area, reduce total runoff from the glacierized part of the basin by up to 7%.","lang":"eng"}],"date_published":"2012-09-27T00:00:00Z","language":[{"iso":"eng"}],"day":"27","publication_status":"published","article_number":"D18105","scopus_import":"1","article_processing_charge":"No","oa_version":"Published Version","doi":"10.1029/2012jd017795","intvolume":"       117","_id":"12648","author":[{"last_name":"Reid","first_name":"T. D.","full_name":"Reid, T. D."},{"last_name":"Carenzo","full_name":"Carenzo, M.","first_name":"M."},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca"},{"last_name":"Brock","full_name":"Brock, B. W.","first_name":"B. W."}],"status":"public","quality_controlled":"1","fulldoi":"https://doi.org/10.1029/2012jd017795"},{"day":"08","oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.5061/dryad.0g0fs"}],"department":[{"_id":"NiBa"}],"date_created":"2023-05-23T17:01:02Z","year":"2012","month":"06","title":"Data from: A likelihood-based comparison of population histories in a parasitoid guild","citation":{"mla":"Lohse, Konrad, et al. <i>Data from: A Likelihood-Based Comparison of Population Histories in a Parasitoid Guild</i>. Dryad, 2012, doi:<a href=\"https://doi.org/10.5061/DRYAD.0G0FS\">10.5061/DRYAD.0G0FS</a>.","ista":"Lohse K, Barton NH, Stone G, Melika G. 2012. Data from: A likelihood-based comparison of population histories in a parasitoid guild, Dryad, <a href=\"https://doi.org/10.5061/DRYAD.0G0FS\">10.5061/DRYAD.0G0FS</a>.","apa":"Lohse, K., Barton, N. H., Stone, G., &#38; Melika, G. (2012). Data from: A likelihood-based comparison of population histories in a parasitoid guild. Dryad. <a href=\"https://doi.org/10.5061/DRYAD.0G0FS\">https://doi.org/10.5061/DRYAD.0G0FS</a>","short":"K. Lohse, N.H. Barton, G. Stone, G. Melika, (2012).","ieee":"K. Lohse, N. H. Barton, G. Stone, and G. Melika, “Data from: A likelihood-based comparison of population histories in a parasitoid guild.” Dryad, 2012.","ama":"Lohse K, Barton NH, Stone G, Melika G. Data from: A likelihood-based comparison of population histories in a parasitoid guild. 2012. doi:<a href=\"https://doi.org/10.5061/DRYAD.0G0FS\">10.5061/DRYAD.0G0FS</a>","chicago":"Lohse, Konrad, Nicholas H Barton, Graham Stone, and George Melika. “Data from: A Likelihood-Based Comparison of Population Histories in a Parasitoid Guild.” Dryad, 2012. <a href=\"https://doi.org/10.5061/DRYAD.0G0FS\">https://doi.org/10.5061/DRYAD.0G0FS</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Little is known about the stability of trophic relationships in complex natural communities over evolutionary timescales. Here, we use sequence data from 18 nuclear loci to reconstruct and compare the intraspecific histories of major Pleistocene refugial populations in the Middle East, the Balkans and Iberia in a guild of four Chalcid parasitoids (Cecidostiba fungosa, C. semifascia, Hobbya stenonota and Mesopolobus amaenus) all attacking Cynipid oak galls. We develop a likelihood method to numerically estimate models of divergence between three populations from multilocus data. We investigate the power of this framework on simulated data, and - using triplet alignments of intronic loci - quantify the support for all possible divergence relationships between refugial populations in the four parasitoids. Although an East to West order of population divergence has highest support in all but one species, we cannot rule out alternative population tree topologies. Comparing the estimated times of population splits between species, we find that one species, M. amaenus, has a significantly older history than the rest of the guild and must have arrived in central Europe at least one glacial cycle prior to other guild members. This suggests that although all four species may share a common origin in the East, they expanded westwards into Europe at different times."}],"date_published":"2012-06-08T00:00:00Z","type":"research_data_reference","publisher":"Dryad","oa_version":"Published Version","doi":"10.5061/DRYAD.0G0FS","status":"public","_id":"13075","related_material":{"record":[{"id":"2968","status":"public","relation":"used_in_publication"}]},"author":[{"first_name":"Konrad","full_name":"Lohse, Konrad","last_name":"Lohse"},{"first_name":"Nicholas H","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton"},{"first_name":"Graham","full_name":"Stone, Graham","last_name":"Stone"},{"first_name":"George","full_name":"Melika, George","last_name":"Melika"}],"fulldoi":"https://doi.org/10.5061/DRYAD.0G0FS","ddc":["570"],"tmp":{"name":"Creative Commons Public Domain Dedication (CC0 1.0)","image":"/images/cc_0.png","short":"CC0 (1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode"},"date_updated":"2025-09-30T08:04:02Z","license":"https://creativecommons.org/publicdomain/zero/1.0/","article_processing_charge":"No"},{"date_updated":"2021-01-12T06:55:19Z","publist_id":"4933","fulldoi":"https://doi.org/10.1145/2185520.2185543","status":"public","_id":"2101","quality_controlled":0,"author":[{"full_name":"Bac̈her, Moritz","first_name":"Moritz","last_name":"Bac̈Her"},{"last_name":"Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","full_name":"Bernd Bickel","first_name":"Bernd"},{"first_name":"Doug","full_name":"James, Doug L","last_name":"James"},{"full_name":"Pfister, Hanspeter","first_name":"Hanspeter","last_name":"Pfister"}],"intvolume":"        31","doi":"10.1145/2185520.2185543","publisher":"ACM","type":"journal_article","volume":31,"abstract":[{"text":"Articulated deformable characters are widespread in computer animation. Unfortunately, we lack methods for their automatic fabrication using modern additive manufacturing (AM) technologies. We propose a method that takes a skinned mesh as input, then estimates a fabricatable single-material model that approximates the 3D kinematics of the corresponding virtual articulated character in a piecewise linear manner. We first extract a set of potential joint locations. From this set, together with optional, user-specified range constraints, we then estimate mechanical friction joints that satisfy inter-joint non-penetration and other fabrication constraints. To avoid brittle joint designs, we place joint centers on an approximate medial axis representation of the input geometry, and maximize each joint's minimal cross-sectional area. We provide several demonstrations, manufactured as single, assembled pieces using 3D printers. ","lang":"eng"}],"date_published":"2012-01-01T00:00:00Z","acknowledgement":"This work was partially supported by NSF grant IIS-1116619. Doug James acknowledges support from Pixar and a fellowship from the John Simon Guggenheim Memorial Foundation","publication":"ACM Transactions on Graphics","citation":{"ista":"Bac̈Her M, Bickel B, James D, Pfister H. 2012. Fabricating articulated characters from skinned meshes. ACM Transactions on Graphics. 31(4).","mla":"Bac̈Her, Moritz, et al. “Fabricating Articulated Characters from Skinned Meshes.” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4, ACM, 2012, doi:<a href=\"https://doi.org/10.1145/2185520.2185543\">10.1145/2185520.2185543</a>.","ama":"Bac̈Her M, Bickel B, James D, Pfister H. Fabricating articulated characters from skinned meshes. <i>ACM Transactions on Graphics</i>. 2012;31(4). doi:<a href=\"https://doi.org/10.1145/2185520.2185543\">10.1145/2185520.2185543</a>","chicago":"Bac̈Her, Moritz, Bernd Bickel, Doug James, and Hanspeter Pfister. “Fabricating Articulated Characters from Skinned Meshes.” <i>ACM Transactions on Graphics</i>. ACM, 2012. <a href=\"https://doi.org/10.1145/2185520.2185543\">https://doi.org/10.1145/2185520.2185543</a>.","ieee":"M. Bac̈Her, B. Bickel, D. James, and H. Pfister, “Fabricating articulated characters from skinned meshes,” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4. ACM, 2012.","apa":"Bac̈Her, M., Bickel, B., James, D., &#38; Pfister, H. (2012). Fabricating articulated characters from skinned meshes. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2185520.2185543\">https://doi.org/10.1145/2185520.2185543</a>","short":"M. Bac̈Her, B. Bickel, D. James, H. Pfister, ACM Transactions on Graphics 31 (2012)."},"month":"01","title":"Fabricating articulated characters from skinned meshes","year":"2012","issue":"4","date_created":"2018-12-11T11:55:43Z","publication_status":"published","extern":1,"day":"01"},{"publication_status":"published","day":"04","extern":1,"publication":"ACM Transactions on Graphics","title":"Physical face cloning","citation":{"short":"B. Bickel, P. Kaufmann, M. Skouras, B. Thomaszewski, D. Bradley, T. Beeler, P. Jackson, S. Marschner, W. Matusik, M. Groß, ACM Transactions on Graphics 31 (2012).","apa":"Bickel, B., Kaufmann, P., Skouras, M., Thomaszewski, B., Bradley, D., Beeler, T., … Groß, M. (2012). Physical face cloning. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2185520.2185614\">https://doi.org/10.1145/2185520.2185614</a>","ieee":"B. Bickel <i>et al.</i>, “Physical face cloning,” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4. ACM, 2012.","chicago":"Bickel, Bernd, Peter Kaufmann, Mélina Skouras, Bernhard Thomaszewski, Derek Bradley, Thabo Beeler, Philip Jackson, Steve Marschner, Wojciech Matusik, and Markus Groß. “Physical Face Cloning.” <i>ACM Transactions on Graphics</i>. ACM, 2012. <a href=\"https://doi.org/10.1145/2185520.2185614\">https://doi.org/10.1145/2185520.2185614</a>.","ama":"Bickel B, Kaufmann P, Skouras M, et al. Physical face cloning. <i>ACM Transactions on Graphics</i>. 2012;31(4). doi:<a href=\"https://doi.org/10.1145/2185520.2185614\">10.1145/2185520.2185614</a>","mla":"Bickel, Bernd, et al. “Physical Face Cloning.” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4, ACM, 2012, doi:<a href=\"https://doi.org/10.1145/2185520.2185614\">10.1145/2185520.2185614</a>.","ista":"Bickel B, Kaufmann P, Skouras M, Thomaszewski B, Bradley D, Beeler T, Jackson P, Marschner S, Matusik W, Groß M. 2012. Physical face cloning. ACM Transactions on Graphics. 31(4)."},"month":"07","acknowledgement":"This work was supported in part by the NCCR Co-Me of the Swiss NSF","abstract":[{"text":"We propose a complete process for designing, simulating, and fabricating synthetic skin for an animatronics character that mimics the face of a given subject and its expressions. The process starts with measuring the elastic properties of a material used to manufacture synthetic soft tissue. Given these measurements we use physicsbased simulation to predict the behavior of a face when it is driven by the underlying robotic actuation. Next, we capture 3D facial expressions for a given target subject. As the key component of our process, we present a novel optimization scheme that determines the shape of the synthetic skin as well as the actuation parameters that provide the best match to the target expressions. We demonstrate this computational skin design by physically cloning a real human face onto an animatronics figure. ","lang":"eng"}],"date_published":"2012-07-04T00:00:00Z","volume":31,"date_created":"2018-12-11T11:55:43Z","issue":"4","year":"2012","publist_id":"4931","fulldoi":"https://doi.org/10.1145/2185520.2185614","type":"journal_article","publisher":"ACM","doi":"10.1145/2185520.2185614","intvolume":"        31","_id":"2102","author":[{"first_name":"Bernd","full_name":"Bernd Bickel","orcid":"0000-0001-6511-9385","id":"49876194-F248-11E8-B48F-1D18A9856A87","last_name":"Bickel"},{"full_name":"Kaufmann, Peter","first_name":"Peter","last_name":"Kaufmann"},{"last_name":"Skouras","full_name":"Skouras, Mélina","first_name":"Mélina"},{"last_name":"Thomaszewski","first_name":"Bernhard","full_name":"Thomaszewski, Bernhard"},{"full_name":"Bradley, Derek J","first_name":"Derek","last_name":"Bradley"},{"last_name":"Beeler","full_name":"Beeler, Thabo","first_name":"Thabo"},{"first_name":"Philip","full_name":"Jackson, Philip V","last_name":"Jackson"},{"last_name":"Marschner","first_name":"Steve","full_name":"Marschner, Steve"},{"first_name":"Wojciech","full_name":"Matusik, Wojciech","last_name":"Matusik"},{"first_name":"Markus","full_name":"Groß, Markus S","last_name":"Groß"}],"quality_controlled":0,"status":"public","date_updated":"2021-01-12T06:55:19Z"},{"publication":"ACM Transactions on Graphics","citation":{"ista":"Beeler T, Bickel B, Noris G, Beardsley P, Marschner S, Sumner R, Groß M. 2012. Coupled 3D reconstruction of sparse facial hair and skin. ACM Transactions on Graphics. 31(4).","mla":"Beeler, Thabo, et al. “Coupled 3D Reconstruction of Sparse Facial Hair and Skin.” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4, ACM, 2012, doi:<a href=\"https://doi.org/10.1145/2185520.2185613\">10.1145/2185520.2185613</a>.","ieee":"T. Beeler <i>et al.</i>, “Coupled 3D reconstruction of sparse facial hair and skin,” <i>ACM Transactions on Graphics</i>, vol. 31, no. 4. ACM, 2012.","short":"T. Beeler, B. Bickel, G. Noris, P. Beardsley, S. Marschner, R. Sumner, M. Groß, ACM Transactions on Graphics 31 (2012).","apa":"Beeler, T., Bickel, B., Noris, G., Beardsley, P., Marschner, S., Sumner, R., &#38; Groß, M. (2012). Coupled 3D reconstruction of sparse facial hair and skin. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2185520.2185613\">https://doi.org/10.1145/2185520.2185613</a>","ama":"Beeler T, Bickel B, Noris G, et al. Coupled 3D reconstruction of sparse facial hair and skin. <i>ACM Transactions on Graphics</i>. 2012;31(4). doi:<a href=\"https://doi.org/10.1145/2185520.2185613\">10.1145/2185520.2185613</a>","chicago":"Beeler, Thabo, Bernd Bickel, Gioacchino Noris, Paul Beardsley, Steve Marschner, Robert Sumner, and Markus Groß. “Coupled 3D Reconstruction of Sparse Facial Hair and Skin.” <i>ACM Transactions on Graphics</i>. ACM, 2012. <a href=\"https://doi.org/10.1145/2185520.2185613\">https://doi.org/10.1145/2185520.2185613</a>."},"month":"01","title":"Coupled 3D reconstruction of sparse facial hair and skin","abstract":[{"lang":"eng","text":"Although facial hair plays an important role in individual expression, facial-hair reconstruction is not addressed by current facecapture systems. Our research addresses this limitation with an algorithm that treats hair and skin surface capture together in a coupled fashion so that a high-quality representation of hair fibers as well as the underlying skin surface can be reconstructed. We propose a passive, camera-based system that is robust against arbitrary motion since all data is acquired within the time period of a single exposure. Our reconstruction algorithm detects and traces hairs in the captured images and reconstructs them in 3D using a multiview stereo approach. Our coupled skin-reconstruction algorithm uses information about the detected hairs to deliver a skin surface that lies underneath all hairs irrespective of occlusions. In dense regions like eyebrows, we employ a hair-synthesis method to create hair fibers that plausibly match the image data. We demonstrate our scanning system on a number of individuals and show that it can successfully reconstruct a variety of facial-hair styles together with the underlying skin surface."}],"date_published":"2012-01-01T00:00:00Z","volume":31,"issue":"4","date_created":"2018-12-11T11:55:44Z","year":"2012","publication_status":"published","extern":1,"day":"01","date_updated":"2021-01-12T06:55:20Z","fulldoi":"https://doi.org/10.1145/2185520.2185613","publist_id":"4932","publisher":"ACM","type":"journal_article","quality_controlled":0,"_id":"2103","status":"public","author":[{"full_name":"Beeler, Thabo","first_name":"Thabo","last_name":"Beeler"},{"last_name":"Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","full_name":"Bernd Bickel","first_name":"Bernd"},{"full_name":"Noris, Gioacchino","first_name":"Gioacchino","last_name":"Noris"},{"first_name":"Paul","full_name":"Beardsley, Paul A","last_name":"Beardsley"},{"full_name":"Marschner, Steve","first_name":"Steve","last_name":"Marschner"},{"first_name":"Robert","full_name":"Sumner, Robert W","last_name":"Sumner"},{"full_name":"Groß, Markus S","first_name":"Markus","last_name":"Groß"}],"doi":"10.1145/2185520.2185613","intvolume":"        31"},{"date_created":"2018-12-11T11:55:44Z","year":"2012","citation":{"ista":"Otaduy M, Bickel B, Bradley D, Wang H. 2012. Data-driven simulation methods in computer graphics: Cloth, tissue and faces. SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques.","mla":"Otaduy, Miguel, et al. <i>Data-Driven Simulation Methods in Computer Graphics: Cloth, Tissue and Faces</i>. ACM, 2012, doi:<a href=\"https://doi.org/10.1145/2343483.2343495\">10.1145/2343483.2343495</a>.","ieee":"M. Otaduy, B. Bickel, D. Bradley, and H. Wang, “Data-driven simulation methods in computer graphics: Cloth, tissue and faces,” presented at the SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques, 2012.","short":"M. Otaduy, B. Bickel, D. Bradley, H. Wang, in:, ACM, 2012.","apa":"Otaduy, M., Bickel, B., Bradley, D., &#38; Wang, H. (2012). Data-driven simulation methods in computer graphics: Cloth, tissue and faces. Presented at the SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques, ACM. <a href=\"https://doi.org/10.1145/2343483.2343495\">https://doi.org/10.1145/2343483.2343495</a>","chicago":"Otaduy, Miguel, Bernd Bickel, Derek Bradley, and Huamin Wang. “Data-Driven Simulation Methods in Computer Graphics: Cloth, Tissue and Faces.” ACM, 2012. <a href=\"https://doi.org/10.1145/2343483.2343495\">https://doi.org/10.1145/2343483.2343495</a>.","ama":"Otaduy M, Bickel B, Bradley D, Wang H. Data-driven simulation methods in computer graphics: Cloth, tissue and faces. In: ACM; 2012. doi:<a href=\"https://doi.org/10.1145/2343483.2343495\">10.1145/2343483.2343495</a>"},"title":"Data-driven simulation methods in computer graphics: Cloth, tissue and faces","month":"01","date_published":"2012-01-01T00:00:00Z","abstract":[{"text":"In recent years, various methods have been introduced to exploit pre-recorded data to improve the performance and/or realism of dynamic deformations, but their differences and similarities have not been adequately analyzed or discussed. So far, the proposed methods have been explored mainly in the research context. They have not been adopted by the computer graphics industry. This course bridges the gap between research labs and industry to present a unifying theory and understanding of data-driven methods for dynamic deformations that may inspire development of novel solutions. It focuses on application of data-driven methods to three areas of computer animation: dynamic deformation of faces, soft volumetric tissue, and cloth. And it describes how to approach these challenges in a data-driven manner, classifies the various methods, and demonstrates how data-driven methods can work in other settings. ","lang":"eng"}],"extern":1,"day":"01","publication_status":"published","conference":{"name":"SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques"},"date_updated":"2021-01-12T06:55:20Z","publisher":"ACM","type":"conference","quality_controlled":0,"_id":"2104","status":"public","author":[{"last_name":"Otaduy","first_name":"Miguel","full_name":"Otaduy, Miguel A"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","last_name":"Bickel","first_name":"Bernd","full_name":"Bernd Bickel"},{"first_name":"Derek","full_name":"Bradley, Derek J","last_name":"Bradley"},{"first_name":"Huamin","full_name":"Wang, Huamin","last_name":"Wang"}],"doi":"10.1145/2343483.2343495","fulldoi":"https://doi.org/10.1145/2343483.2343495","publist_id":"4930"},{"publication_status":"published","day":"01","extern":1,"date_published":"2012-05-01T00:00:00Z","volume":31,"title":"Computational design of rubber balloons","citation":{"ieee":"M. Skouras, B. Thomaszewski, B. Bickel, and M. Groß, “Computational design of rubber balloons,” presented at the EUROGRAPHICS: European Association for Computer Graphics, 2012, vol. 31, no. 2, pp. 835–844.","short":"M. Skouras, B. Thomaszewski, B. Bickel, M. Groß, in:, Wiley-Blackwell, 2012, pp. 835–844.","apa":"Skouras, M., Thomaszewski, B., Bickel, B., &#38; Groß, M. (2012). Computational design of rubber balloons (Vol. 31, pp. 835–844). Presented at the EUROGRAPHICS: European Association for Computer Graphics, Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.1467-8659.2012.03064.x\">https://doi.org/10.1111/j.1467-8659.2012.03064.x</a>","chicago":"Skouras, Mélina, Bernhard Thomaszewski, Bernd Bickel, and Markus Groß. “Computational Design of Rubber Balloons,” 31:835–44. Wiley-Blackwell, 2012. <a href=\"https://doi.org/10.1111/j.1467-8659.2012.03064.x\">https://doi.org/10.1111/j.1467-8659.2012.03064.x</a>.","ama":"Skouras M, Thomaszewski B, Bickel B, Groß M. Computational design of rubber balloons. In: Vol 31. Wiley-Blackwell; 2012:835-844. doi:<a href=\"https://doi.org/10.1111/j.1467-8659.2012.03064.x\">10.1111/j.1467-8659.2012.03064.x</a>","mla":"Skouras, Mélina, et al. <i>Computational Design of Rubber Balloons</i>. Vol. 31, no. 2, Wiley-Blackwell, 2012, pp. 835–44, doi:<a href=\"https://doi.org/10.1111/j.1467-8659.2012.03064.x\">10.1111/j.1467-8659.2012.03064.x</a>.","ista":"Skouras M, Thomaszewski B, Bickel B, Groß M. 2012. Computational design of rubber balloons. EUROGRAPHICS: European Association for Computer Graphics vol. 31, 835–844."},"month":"05","acknowledgement":"Mélina Skouras was partially supported by the NCCR Co-Me of the Swiss National Science Foundation.","year":"2012","date_created":"2018-12-11T11:55:45Z","issue":"2","fulldoi":"https://doi.org/10.1111/j.1467-8659.2012.03064.x","publist_id":"4928","intvolume":"        31","doi":"10.1111/j.1467-8659.2012.03064.x","_id":"2105","quality_controlled":0,"author":[{"first_name":"Mélina","full_name":"Skouras, Mélina","last_name":"Skouras"},{"full_name":"Thomaszewski, Bernhard","first_name":"Bernhard","last_name":"Thomaszewski"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","last_name":"Bickel","first_name":"Bernd","full_name":"Bernd Bickel"},{"last_name":"Groß","full_name":"Groß, Markus S","first_name":"Markus"}],"page":"835 - 844","status":"public","type":"conference","publisher":"Wiley-Blackwell","date_updated":"2021-01-12T06:55:20Z","conference":{"name":"EUROGRAPHICS: European Association for Computer Graphics"}},{"day":"01","extern":1,"publication_status":"published","date_created":"2018-12-11T11:55:45Z","issue":"2","year":"2012","citation":{"short":"E. Miguel, D. Bradley, B. Thomaszewski, B. Bickel, W. Matusik, M. Otaduy, S. Marschner, in:, Wiley-Blackwell, 2012, pp. 519–528.","ieee":"E. Miguel <i>et al.</i>, “Data-driven estimation of cloth simulation models,” presented at the Computer Graphics Forum, 2012, vol. 31, no. 2, pp. 519–528.","apa":"Miguel, E., Bradley, D., Thomaszewski, B., Bickel, B., Matusik, W., Otaduy, M., &#38; Marschner, S. (2012). Data-driven estimation of cloth simulation models (Vol. 31, pp. 519–528). Presented at the Computer Graphics Forum, Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.1467-8659.2012.03031.x\">https://doi.org/10.1111/j.1467-8659.2012.03031.x</a>","ama":"Miguel E, Bradley D, Thomaszewski B, et al. Data-driven estimation of cloth simulation models. In: Vol 31. Wiley-Blackwell; 2012:519-528. doi:<a href=\"https://doi.org/10.1111/j.1467-8659.2012.03031.x\">10.1111/j.1467-8659.2012.03031.x</a>","chicago":"Miguel, Eder, Derek Bradley, Bernhard Thomaszewski, Bernd Bickel, Wojciech Matusik, Miguel Otaduy, and Steve Marschner. “Data-Driven Estimation of Cloth Simulation Models,” 31:519–28. Wiley-Blackwell, 2012. <a href=\"https://doi.org/10.1111/j.1467-8659.2012.03031.x\">https://doi.org/10.1111/j.1467-8659.2012.03031.x</a>.","ista":"Miguel E, Bradley D, Thomaszewski B, Bickel B, Matusik W, Otaduy M, Marschner S. 2012. Data-driven estimation of cloth simulation models. Computer Graphics Forum vol. 31, 519–528.","mla":"Miguel, Eder, et al. <i>Data-Driven Estimation of Cloth Simulation Models</i>. Vol. 31, no. 2, Wiley-Blackwell, 2012, pp. 519–28, doi:<a href=\"https://doi.org/10.1111/j.1467-8659.2012.03031.x\">10.1111/j.1467-8659.2012.03031.x</a>."},"month":"05","title":"Data-driven estimation of cloth simulation models","acknowledgement":"This work was funded in part by the Spanish Ministry of Science and Innovation, project TIN2009-07942, and by the European Research Council, project ERC-2011-StG-280135 Animetrics.","volume":31,"abstract":[{"lang":"eng","text":"Progress in cloth simulation for computer animation and apparel design has led to a multitude of deformation models, each with its own way of relating geometry, deformation, and forces. As simulators improve, differences between these models become more important, but it is difficult to choose a model and a set of parameters to match a given real material simply by looking at simulation results. This paper provides measurement and fitting methods that allow nonlinear models to be fit to the observed deformation of a particular cloth sample. Unlike standard textile testing, our system measures complex 3D deformations of a sheet of cloth, not just one-dimensional force-displacement curves, so it works under a wider range of deformation conditions. The fitted models are then evaluated by comparison to measured deformations with motions very different from those used for fitting."}],"date_published":"2012-05-01T00:00:00Z","type":"conference","publisher":"Wiley-Blackwell","intvolume":"        31","doi":"10.1111/j.1467-8659.2012.03031.x","_id":"2106","author":[{"last_name":"Miguel","full_name":"Miguel, Eder","first_name":"Eder"},{"last_name":"Bradley","first_name":"Derek","full_name":"Bradley, Derek J"},{"last_name":"Thomaszewski","first_name":"Bernhard","full_name":"Thomaszewski, Bernhard"},{"full_name":"Bernd Bickel","first_name":"Bernd","last_name":"Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385"},{"full_name":"Matusik, Wojciech","first_name":"Wojciech","last_name":"Matusik"},{"last_name":"Otaduy","first_name":"Miguel","full_name":"Otaduy, Miguel A"},{"full_name":"Marschner, Steve","first_name":"Steve","last_name":"Marschner"}],"page":"519 - 528","status":"public","quality_controlled":0,"fulldoi":"https://doi.org/10.1111/j.1467-8659.2012.03031.x","publist_id":"4929","conference":{"name":"Computer Graphics Forum"},"date_updated":"2021-01-12T06:55:21Z"},{"page":"1420-1426","type":"journal_article","publisher":"International Union of Crystallography","publication_identifier":{"issn":["1744-3091"]},"article_type":"original","date_updated":"2026-02-23T09:07:01Z","extern":"1","date_created":"2026-01-29T21:59:50Z","issue":"12","volume":68,"publication":"Acta Crystallographica Section F Structural Biology Communications","has_accepted_license":"1","doi":"10.1107/s1744309112041759","intvolume":"        68","author":[{"last_name":"Mandal","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","orcid":"0000-0001-5996-956X","full_name":"Mandal, Pradeep K","first_name":"Pradeep K"},{"first_name":"S.","full_name":"Venkadesh, S.","last_name":"Venkadesh"},{"first_name":"N.","full_name":"Gautham, N.","last_name":"Gautham"}],"quality_controlled":"1","_id":"21104","status":"public","oa_version":"None","fulldoi":"https://doi.org/10.1107/s1744309112041759","article_processing_charge":"No","day":"01","language":[{"iso":"eng"}],"OA_type":"closed access","publication_status":"published","year":"2012","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Crystal structures of the hexanucleotide d(CACGCG)·d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn2+ were used in crystallization. The availability of Mn2+ during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P21 and P65. Analysis of the molecular interactions of Mn2+ with the Z-form duplexes shows direct coordination to the purine residues G and A.","lang":"eng"}],"date_published":"2012-12-01T00:00:00Z","title":"Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex","citation":{"mla":"Mandal, Pradeep K., et al. “Interactions of Mn2+ with a Non-Self-Complementary Z-Type DNA Duplex.” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 68, no. 12, International Union of Crystallography, 2012, pp. 1420–26, doi:<a href=\"https://doi.org/10.1107/s1744309112041759\">10.1107/s1744309112041759</a>.","ista":"Mandal PK, Venkadesh S, Gautham N. 2012. Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex. Acta Crystallographica Section F Structural Biology Communications. 68(12), 1420–1426.","chicago":"Mandal, Pradeep K, S. Venkadesh, and N. Gautham. “Interactions of Mn2+ with a Non-Self-Complementary Z-Type DNA Duplex.” <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography, 2012. <a href=\"https://doi.org/10.1107/s1744309112041759\">https://doi.org/10.1107/s1744309112041759</a>.","ama":"Mandal PK, Venkadesh S, Gautham N. Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex. <i>Acta Crystallographica Section F Structural Biology Communications</i>. 2012;68(12):1420-1426. doi:<a href=\"https://doi.org/10.1107/s1744309112041759\">10.1107/s1744309112041759</a>","short":"P.K. Mandal, S. Venkadesh, N. Gautham, Acta Crystallographica Section F Structural Biology Communications 68 (2012) 1420–1426.","ieee":"P. K. Mandal, S. Venkadesh, and N. Gautham, “Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex,” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 68, no. 12. International Union of Crystallography, pp. 1420–1426, 2012.","apa":"Mandal, P. K., Venkadesh, S., &#38; Gautham, N. (2012). Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex. <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/s1744309112041759\">https://doi.org/10.1107/s1744309112041759</a>"},"month":"12"},{"author":[{"orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal","first_name":"Pradeep K","full_name":"Mandal, Pradeep K"},{"last_name":"Chandrasekaran","first_name":"Arun Richard","full_name":"Chandrasekaran, Arun Richard"},{"full_name":"Madhanagopal, Bharath Raj","first_name":"Bharath Raj","last_name":"Madhanagopal"},{"last_name":"Venkadesh","full_name":"Venkadesh, Sarkarai","first_name":"Sarkarai"},{"full_name":"Gautham, Namasivayam","first_name":"Namasivayam","last_name":"Gautham"}],"status":"public","quality_controlled":"1","_id":"21105","doi":"10.1016/j.jcrysgro.2012.05.029","intvolume":"       354","oa_version":"None","fulldoi":"https://doi.org/10.1016/j.jcrysgro.2012.05.029","article_processing_charge":"No","day":"01","language":[{"iso":"eng"}],"OA_type":"closed access","publication_status":"published","year":"2012","abstract":[{"text":"The hexamer duplex d(CACGCG).d(CGCGTG) produces unusual hexagonal ring shaped crystals when crystallized in the presence of cobalt hexammine chloride. Observation of the growth of these crystals over a period of about 6 days indicated that this morphology resulted from radial dissolution of the crystal from the center of the well-formed hexagonal plates. X-ray diffraction studies were carried out for crystals of four stages in the ring crystal morphology. The structure of the DNA in all four crystals was the Z type DNA double helix. The packing mode of the Z DNA duplex in all four crystal structures was that of the ‘spermine’ form. The crystal morphology changes from hexagonal plates to hexagonal rings without any apparent change in the molecular structure of the oligonucleotide or helical packing of the duplexes.","lang":"eng"}],"date_published":"2012-09-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies","month":"09","citation":{"chicago":"Mandal, Pradeep K, Arun Richard Chandrasekaran, Bharath Raj Madhanagopal, Sarkarai Venkadesh, and Namasivayam Gautham. “Ring Crystals of Oligonucleotides: Growth Stages and X-Ray Diffraction Studies.” <i>Journal of Crystal Growth</i>. Elsevier, 2012. <a href=\"https://doi.org/10.1016/j.jcrysgro.2012.05.029\">https://doi.org/10.1016/j.jcrysgro.2012.05.029</a>.","ama":"Mandal PK, Chandrasekaran AR, Madhanagopal BR, Venkadesh S, Gautham N. Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies. <i>Journal of Crystal Growth</i>. 2012;354(1):20-26. doi:<a href=\"https://doi.org/10.1016/j.jcrysgro.2012.05.029\">10.1016/j.jcrysgro.2012.05.029</a>","apa":"Mandal, P. K., Chandrasekaran, A. R., Madhanagopal, B. R., Venkadesh, S., &#38; Gautham, N. (2012). Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies. <i>Journal of Crystal Growth</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jcrysgro.2012.05.029\">https://doi.org/10.1016/j.jcrysgro.2012.05.029</a>","ieee":"P. K. Mandal, A. R. Chandrasekaran, B. R. Madhanagopal, S. Venkadesh, and N. Gautham, “Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies,” <i>Journal of Crystal Growth</i>, vol. 354, no. 1. Elsevier, pp. 20–26, 2012.","short":"P.K. Mandal, A.R. Chandrasekaran, B.R. Madhanagopal, S. Venkadesh, N. Gautham, Journal of Crystal Growth 354 (2012) 20–26.","ista":"Mandal PK, Chandrasekaran AR, Madhanagopal BR, Venkadesh S, Gautham N. 2012. Ring crystals of oligonucleotides: Growth stages and X-ray diffraction studies. Journal of Crystal Growth. 354(1), 20–26.","mla":"Mandal, Pradeep K., et al. “Ring Crystals of Oligonucleotides: Growth Stages and X-Ray Diffraction Studies.” <i>Journal of Crystal Growth</i>, vol. 354, no. 1, Elsevier, 2012, pp. 20–26, doi:<a href=\"https://doi.org/10.1016/j.jcrysgro.2012.05.029\">10.1016/j.jcrysgro.2012.05.029</a>."},"page":"20-26","publisher":"Elsevier","type":"journal_article","publication_identifier":{"issn":["0022-0248"]},"article_type":"original","date_updated":"2026-02-20T09:15:22Z","extern":"1","issue":"1","date_created":"2026-01-29T22:02:59Z","volume":354,"has_accepted_license":"1","publication":"Journal of Crystal Growth"},{"year":"2012","month":"04","title":"Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex","citation":{"ista":"Mandal PK, Venkadesh S, Gautham N. 2012. Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. Acta Crystallographica Section F Structural Biology Communications. 68(4), 393–399.","mla":"Mandal, Pradeep K., et al. “Structure of the Tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA Duplex.” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 68, no. 4, International Union of Crystallography, 2012, pp. 393–99, doi:<a href=\"https://doi.org/10.1107/s174430911200869x\">10.1107/s174430911200869x</a>.","ama":"Mandal PK, Venkadesh S, Gautham N. Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. <i>Acta Crystallographica Section F Structural Biology Communications</i>. 2012;68(4):393-399. doi:<a href=\"https://doi.org/10.1107/s174430911200869x\">10.1107/s174430911200869x</a>","chicago":"Mandal, Pradeep K, Sarkarai Venkadesh, and Namasivayam Gautham. “Structure of the Tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA Duplex.” <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography, 2012. <a href=\"https://doi.org/10.1107/s174430911200869x\">https://doi.org/10.1107/s174430911200869x</a>.","short":"P.K. Mandal, S. Venkadesh, N. Gautham, Acta Crystallographica Section F Structural Biology Communications 68 (2012) 393–399.","ieee":"P. K. Mandal, S. Venkadesh, and N. Gautham, “Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex,” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 68, no. 4. International Union of Crystallography, pp. 393–399, 2012.","apa":"Mandal, P. K., Venkadesh, S., &#38; Gautham, N. (2012). Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/s174430911200869x\">https://doi.org/10.1107/s174430911200869x</a>"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"The crystal structure of the tetradecanucleotide sequence d(CCCCGGTACC­GGGG)2 has been determined at 2.5 Å resolution in the tetragonal space group P41. This sequence was designed with the expectation of a four-way junction. However, the sequence crystallized as an A-DNA duplex and represents more than one full turn of the A-helix. The crystallographic asymmetric unit consists of one tetradecanucleotide duplex. The structural parameters of the A-type DNA duplex structure and the crystal-packing arrangement are described. One Mn2+ ion was identified with direct coordination to the N7 position of G13 and a water molecule at the major-groove side of the C2·G13 base pair.","lang":"eng"}],"date_published":"2012-04-01T00:00:00Z","OA_type":"closed access","day":"01","language":[{"iso":"eng"}],"publication_status":"published","article_processing_charge":"No","oa_version":"None","doi":"10.1107/s174430911200869x","intvolume":"        68","status":"public","quality_controlled":"1","author":[{"last_name":"Mandal","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","full_name":"Mandal, Pradeep K","first_name":"Pradeep K"},{"last_name":"Venkadesh","full_name":"Venkadesh, Sarkarai","first_name":"Sarkarai"},{"last_name":"Gautham","first_name":"Namasivayam","full_name":"Gautham, Namasivayam"}],"_id":"21106","fulldoi":"https://doi.org/10.1107/s174430911200869x","date_created":"2026-01-29T22:04:31Z","issue":"4","publication":"Acta Crystallographica Section F Structural Biology Communications","has_accepted_license":"1","volume":68,"extern":"1","article_type":"original","date_updated":"2026-02-23T08:58:07Z","type":"journal_article","publisher":"International Union of Crystallography","page":"393-399","publication_identifier":{"issn":["1744-3091"]}},{"volume":79,"publication":"Chemical Biology & Drug Design","has_accepted_license":"1","date_created":"2026-01-29T22:12:53Z","issue":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1111/j.1747-0285.2011.01258.x"}],"extern":"1","oa":1,"date_updated":"2026-02-20T08:20:52Z","article_type":"original","pmid":1,"publication_identifier":{"eissn":["1747-0285"],"issn":["1747-0277"]},"page":"143-147","type":"journal_article","publisher":"Wiley","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2012-01-01T00:00:00Z","abstract":[{"text":"Inhibiting PLA2 activity should, in theory, be an effective approach to control the inflammation. Several naturally occurring polyphenolic compounds have been reported as inhibitors of PLA2. Among the naturally occurring polyphenols, catechol (1,2-dihydroxybenzene) possesses anti-inflammatory activity. Catechol can inhibit cyclooxygenase and lipo-oxygenase. By means of enzyme kinetic study, it was revealed that catechol can inhibit PLA2 also. Crystal structure showed that catechol binds to PLA2 at the opening of the active site cleft. This might stop the entry of substrate into the active site. Hence, catechol can be used as a lead compound for the development of novel anti-inflammatory drugs with PLA2 as the target.","lang":"eng"}],"month":"01","citation":{"mla":"Dileep, Kalarickal V., et al. “Binding to PLA2 May Contribute to the Anti‐inflammatory Activity of Catechol.” <i>Chemical Biology &#38; Drug Design</i>, vol. 79, no. 1, Wiley, 2012, pp. 143–47, doi:<a href=\"https://doi.org/10.1111/j.1747-0285.2011.01258.x\">10.1111/j.1747-0285.2011.01258.x</a>.","ista":"Dileep KV, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C. 2012. Binding to PLA2 may contribute to the anti‐inflammatory activity of catechol. Chemical Biology &#38; Drug Design. 79(1), 143–147.","short":"K.V. Dileep, I. Tintu, P.K. Mandal, P. Karthe, M. Haridas, C. Sadasivan, Chemical Biology &#38; Drug Design 79 (2012) 143–147.","apa":"Dileep, K. V., Tintu, I., Mandal, P. K., Karthe, P., Haridas, M., &#38; Sadasivan, C. (2012). Binding to PLA2 may contribute to the anti‐inflammatory activity of catechol. <i>Chemical Biology &#38; Drug Design</i>. Wiley. <a href=\"https://doi.org/10.1111/j.1747-0285.2011.01258.x\">https://doi.org/10.1111/j.1747-0285.2011.01258.x</a>","ieee":"K. V. Dileep, I. Tintu, P. K. Mandal, P. Karthe, M. Haridas, and C. Sadasivan, “Binding to PLA2 may contribute to the anti‐inflammatory activity of catechol,” <i>Chemical Biology &#38; Drug Design</i>, vol. 79, no. 1. Wiley, pp. 143–147, 2012.","ama":"Dileep KV, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C. Binding to PLA2 may contribute to the anti‐inflammatory activity of catechol. <i>Chemical Biology &#38; Drug Design</i>. 2012;79(1):143-147. doi:<a href=\"https://doi.org/10.1111/j.1747-0285.2011.01258.x\">10.1111/j.1747-0285.2011.01258.x</a>","chicago":"Dileep, Kalarickal V., Ignatius Tintu, Pradeep K Mandal, Ponnuraj Karthe, Madathilkovilakathu Haridas, and Chittalakkottu Sadasivan. “Binding to PLA2 May Contribute to the Anti‐inflammatory Activity of Catechol.” <i>Chemical Biology &#38; Drug Design</i>. Wiley, 2012. <a href=\"https://doi.org/10.1111/j.1747-0285.2011.01258.x\">https://doi.org/10.1111/j.1747-0285.2011.01258.x</a>."},"title":"Binding to PLA2 may contribute to the anti‐inflammatory activity of catechol","year":"2012","publication_status":"published","language":[{"iso":"eng"}],"day":"01","OA_type":"free access","OA_place":"publisher","article_processing_charge":"No","external_id":{"pmid":["21995306"]},"fulldoi":"https://doi.org/10.1111/j.1747-0285.2011.01258.x","doi":"10.1111/j.1747-0285.2011.01258.x","intvolume":"        79","_id":"21111","status":"public","author":[{"last_name":"Dileep","first_name":"Kalarickal V.","full_name":"Dileep, Kalarickal V."},{"full_name":"Tintu, Ignatius","first_name":"Ignatius","last_name":"Tintu"},{"full_name":"Mandal, Pradeep K","first_name":"Pradeep K","last_name":"Mandal","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3"},{"full_name":"Karthe, Ponnuraj","first_name":"Ponnuraj","last_name":"Karthe"},{"last_name":"Haridas","first_name":"Madathilkovilakathu","full_name":"Haridas, Madathilkovilakathu"},{"full_name":"Sadasivan, Chittalakkottu","first_name":"Chittalakkottu","last_name":"Sadasivan"}],"quality_controlled":"1","oa_version":"Published Version"},{"pmid":1,"publication_identifier":{"issn":["1747-0277"],"eissn":["1747-0285"]},"page":"434-439","type":"journal_article","publisher":"Wiley","date_updated":"2026-02-20T08:23:29Z","article_type":"original","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1111/j.1747-0285.2012.01418.x"}],"oa":1,"extern":"1","volume":80,"publication":"Chemical Biology & Drug Design","has_accepted_license":"1","date_created":"2026-01-29T22:14:04Z","issue":"3","fulldoi":"https://doi.org/10.1111/j.1747-0285.2012.01418.x","doi":"10.1111/j.1747-0285.2012.01418.x","intvolume":"        80","_id":"21112","author":[{"last_name":"Aparna","full_name":"Aparna, Vasudevan","first_name":"Vasudevan"},{"last_name":"Dileep","full_name":"Dileep, Kalarickal V.","first_name":"Kalarickal V."},{"full_name":"Mandal, Pradeep K","first_name":"Pradeep K","last_name":"Mandal","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3"},{"last_name":"Karthe","first_name":"Ponnuraj","full_name":"Karthe, Ponnuraj"},{"full_name":"Sadasivan, Chittalakkottu","first_name":"Chittalakkottu","last_name":"Sadasivan"},{"last_name":"Haridas","full_name":"Haridas, Madathilkovilakathu","first_name":"Madathilkovilakathu"}],"status":"public","quality_controlled":"1","oa_version":"Published Version","article_processing_charge":"No","external_id":{"pmid":["22642495"]},"publication_status":"published","language":[{"iso":"eng"}],"day":"01","OA_type":"free access","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"<jats:p>Ester bond hydrolysis of membrane phospholipids by Phospholipase A2 and consequent release of fatty acids are the initiating steps of inflammation. It is proposed in this study that the inhibition of phospholipase A2 is one of the ways to control inflammation. Investigations are carried out to identify the mode of inhibition of phospholipase A2 by the n‐hexadecanoic acid. It may help in designing of specific inhibitors of phospholipase A2 as anti‐inflammatory agents. The enzyme kinetics study proved that n‐hexadecanoic acid inhibits phospholipase A2 in a competitive manner. It was identified from the crystal structure at 2.5Å resolution that the position of n‐hexadecanoic acid is in the active site of the phospholipase A2. The binding constant and binding energy have also been calculated using Isothermal Titration Calorimetry. Also, the binding energy of n‐hexadecanoic acid to phospholipase A2 was calculated by in silico method and compared with known inhibitors. It may be concluded from the structural and kinetics studies that the fatty acid, n‐hexadecanoic acid, is an inhibitor of phospholipase A2, hence, an anti‐inflammatory compound. The inferences from the present study validate the rigorous use of medicated oils rich in n‐hexadecanoic acid for the treatment of rheumatic symptoms in the traditional medical system of India, Ayurveda.","lang":"eng"}],"date_published":"2012-09-01T00:00:00Z","month":"09","citation":{"ista":"Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C, Haridas M. 2012. Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and kinetic assessment. Chemical Biology &#38; Drug Design. 80(3), 434–439.","mla":"Aparna, Vasudevan, et al. “Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic Assessment.” <i>Chemical Biology &#38; Drug Design</i>, vol. 80, no. 3, Wiley, 2012, pp. 434–39, doi:<a href=\"https://doi.org/10.1111/j.1747-0285.2012.01418.x\">10.1111/j.1747-0285.2012.01418.x</a>.","ama":"Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C, Haridas M. Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and kinetic assessment. <i>Chemical Biology &#38; Drug Design</i>. 2012;80(3):434-439. doi:<a href=\"https://doi.org/10.1111/j.1747-0285.2012.01418.x\">10.1111/j.1747-0285.2012.01418.x</a>","chicago":"Aparna, Vasudevan, Kalarickal V. Dileep, Pradeep K Mandal, Ponnuraj Karthe, Chittalakkottu Sadasivan, and Madathilkovilakathu Haridas. “Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic Assessment.” <i>Chemical Biology &#38; Drug Design</i>. Wiley, 2012. <a href=\"https://doi.org/10.1111/j.1747-0285.2012.01418.x\">https://doi.org/10.1111/j.1747-0285.2012.01418.x</a>.","ieee":"V. Aparna, K. V. Dileep, P. K. Mandal, P. Karthe, C. Sadasivan, and M. Haridas, “Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and kinetic assessment,” <i>Chemical Biology &#38; Drug Design</i>, vol. 80, no. 3. Wiley, pp. 434–439, 2012.","short":"V. Aparna, K.V. Dileep, P.K. Mandal, P. Karthe, C. Sadasivan, M. Haridas, Chemical Biology &#38; Drug Design 80 (2012) 434–439.","apa":"Aparna, V., Dileep, K. V., Mandal, P. K., Karthe, P., Sadasivan, C., &#38; Haridas, M. (2012). Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and kinetic assessment. <i>Chemical Biology &#38; Drug Design</i>. Wiley. <a href=\"https://doi.org/10.1111/j.1747-0285.2012.01418.x\">https://doi.org/10.1111/j.1747-0285.2012.01418.x</a>"},"title":"Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and kinetic assessment","year":"2012"},{"page":"184-196","type":"journal_article","publisher":"Informa UK Limited","pmid":1,"publication_identifier":{"issn":["1525-7770"],"eissn":["1532-2335"]},"article_type":"original","date_updated":"2026-02-20T08:17:42Z","extern":"1","date_created":"2026-02-06T12:10:42Z","issue":"3","volume":31,"publication":"Nucleosides, Nucleotides and Nucleic Acids","has_accepted_license":"1","doi":"10.1080/15257770.2011.648363","intvolume":"        31","status":"public","_id":"21151","author":[{"full_name":"Venkadesh, S.","first_name":"S.","last_name":"Venkadesh"},{"orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal","first_name":"Pradeep K","full_name":"Mandal, Pradeep K"},{"last_name":"Gautham","full_name":"Gautham, N.","first_name":"N."}],"quality_controlled":"1","oa_version":"None","fulldoi":"https://doi.org/10.1080/15257770.2011.648363","external_id":{"pmid":["22356234"]},"article_processing_charge":"No","day":"01","language":[{"iso":"eng"}],"OA_type":"closed access","publication_status":"published","year":"2012","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2012-03-01T00:00:00Z","abstract":[{"lang":"eng","text":"The decanucleotide sequence d(CCGGTACCGG) crystallizes as a four-way junction at low cobalt ion concentrations (i.e., 1 mM). When the cobalt concentration in the crystallization solution is increased to 5 mM, the sequence crystallizes as resolved B-DNA duplexes. Gel retardation studies of the decamer show both a faint slow-moving band and a much thicker fast-moving band at low cobalt ion concentrations, and only the intense fast-moving band at higher ion concentration. Circular dichroism (CD) spectroscopy of the decamer indicates a structural transition as the cobalt ion concentration in the solution is increased, probably from B-type to A-type DNA. These studies revealed that the oligomer sequence has several conformations and structures accessible to it, in a manner dependent on sequence, ion concentration, and DNA concentration."}],"citation":{"mla":"Venkadesh, S., et al. “Crystallographic and Spectroscopic Studies of d(CCGGTACCGG).” <i>Nucleosides, Nucleotides and Nucleic Acids</i>, vol. 31, no. 3, Informa UK Limited, 2012, pp. 184–96, doi:<a href=\"https://doi.org/10.1080/15257770.2011.648363\">10.1080/15257770.2011.648363</a>.","ista":"Venkadesh S, Mandal PK, Gautham N. 2012. Crystallographic and spectroscopic studies of d(CCGGTACCGG). Nucleosides, Nucleotides and Nucleic Acids. 31(3), 184–196.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2012). Crystallographic and spectroscopic studies of d(CCGGTACCGG). <i>Nucleosides, Nucleotides and Nucleic Acids</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/15257770.2011.648363\">https://doi.org/10.1080/15257770.2011.648363</a>","short":"S. Venkadesh, P.K. Mandal, N. Gautham, Nucleosides, Nucleotides and Nucleic Acids 31 (2012) 184–196.","ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “Crystallographic and spectroscopic studies of d(CCGGTACCGG),” <i>Nucleosides, Nucleotides and Nucleic Acids</i>, vol. 31, no. 3. Informa UK Limited, pp. 184–196, 2012.","chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “Crystallographic and Spectroscopic Studies of d(CCGGTACCGG).” <i>Nucleosides, Nucleotides and Nucleic Acids</i>. Informa UK Limited, 2012. <a href=\"https://doi.org/10.1080/15257770.2011.648363\">https://doi.org/10.1080/15257770.2011.648363</a>.","ama":"Venkadesh S, Mandal PK, Gautham N. Crystallographic and spectroscopic studies of d(CCGGTACCGG). <i>Nucleosides, Nucleotides and Nucleic Acids</i>. 2012;31(3):184-196. doi:<a href=\"https://doi.org/10.1080/15257770.2011.648363\">10.1080/15257770.2011.648363</a>"},"month":"03","title":"Crystallographic and spectroscopic studies of d(CCGGTACCGG)"},{"has_accepted_license":"1","publication":"Frontiers in Life Science","volume":5,"issue":"3-4","date_created":"2026-02-06T12:17:45Z","extern":"1","date_updated":"2026-02-20T08:07:19Z","article_type":"original","publication_identifier":{"issn":["2155-3769","2155-3777"]},"publisher":"Informa UK Limited","type":"journal_article","page":"135-139","title":"Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione","month":"08","citation":{"apa":"Dileep, K. V., Tintu, I., Mandal, P. K., Karthe, P., Haridas, M., &#38; Sadasivan, C. (2012). Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione. <i>Frontiers in Life Science</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/21553769.2012.689262\">https://doi.org/10.1080/21553769.2012.689262</a>","short":"K.V. Dileep, I. Tintu, P.K. Mandal, P. Karthe, M. Haridas, C. Sadasivan, Frontiers in Life Science 5 (2012) 135–139.","ieee":"K. V. Dileep, I. Tintu, P. K. Mandal, P. Karthe, M. Haridas, and C. Sadasivan, “Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione,” <i>Frontiers in Life Science</i>, vol. 5, no. 3–4. Informa UK Limited, pp. 135–139, 2012.","ama":"Dileep KV, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C. Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione. <i>Frontiers in Life Science</i>. 2012;5(3-4):135-139. doi:<a href=\"https://doi.org/10.1080/21553769.2012.689262\">10.1080/21553769.2012.689262</a>","chicago":"Dileep, K. V., I. Tintu, Pradeep K Mandal, P. Karthe, M. Haridas, and C. Sadasivan. “Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with 2-Methoxycyclohexa-2-5-Diene-1,4-Dione.” <i>Frontiers in Life Science</i>. Informa UK Limited, 2012. <a href=\"https://doi.org/10.1080/21553769.2012.689262\">https://doi.org/10.1080/21553769.2012.689262</a>.","ista":"Dileep KV, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C. 2012. Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione. Frontiers in Life Science. 5(3–4), 135–139.","mla":"Dileep, K. V., et al. “Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with 2-Methoxycyclohexa-2-5-Diene-1,4-Dione.” <i>Frontiers in Life Science</i>, vol. 5, no. 3–4, Informa UK Limited, 2012, pp. 135–39, doi:<a href=\"https://doi.org/10.1080/21553769.2012.689262\">10.1080/21553769.2012.689262</a>."},"abstract":[{"text":"Curcumin possess anti-inflammatory activity. In this study, the binding of curcumin with PLA2 was studied using X-ray crystallography. Since the electron density found at the active site did not match with curcumin, 2-methoxycyclohexa-2-5-diene-1,4-dione (MCW) (the photodegraded product of curcumin) was fitted in the unexplained electron density. To understand the binding mode of actual curcumin, molecular docking study was carried out. The crystallographic and docked structures were superimposed with respect to the ligand position and it was found that curcumin was binding in the hydrophobic cavity of PLA2 with a binding energy of−16.81 Kcal/mol. The binding mode was of such a nature that it prevented the entry of the substrate to the hydrophobic active site. This study indicates that curcumin can act as an inhibitor of PLA2.\r\n\r\nAn animated Interactive 3D Complement (I3DC) is available in Proteopedia at http://proteopedia.org/w/Journal:FLS:1.","lang":"eng"}],"date_published":"2012-08-06T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2012","publication_status":"published","OA_type":"closed access","language":[{"iso":"eng"}],"day":"06","article_processing_charge":"No","fulldoi":"https://doi.org/10.1080/21553769.2012.689262","oa_version":"None","_id":"21153","quality_controlled":"1","author":[{"full_name":"Dileep, K. V.","first_name":"K. V.","last_name":"Dileep"},{"first_name":"I.","full_name":"Tintu, I.","last_name":"Tintu"},{"last_name":"Mandal","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","orcid":"0000-0001-5996-956X","full_name":"Mandal, Pradeep K","first_name":"Pradeep K"},{"last_name":"Karthe","full_name":"Karthe, P.","first_name":"P."},{"full_name":"Haridas, M.","first_name":"M.","last_name":"Haridas"},{"full_name":"Sadasivan, C.","first_name":"C.","last_name":"Sadasivan"}],"status":"public","intvolume":"         5","doi":"10.1080/21553769.2012.689262"}]