[{"_id":"1299","type":"journal_article","date_updated":"2021-01-12T06:49:43Z","issue":"6","quality_controlled":0,"date_published":"2011-06-23T00:00:00Z","date_created":"2018-12-11T11:51:14Z","publisher":"Elsevier","publist_id":"5969","doi":"10.1016/j.neuron.2011.03.028","extern":1,"month":"06","volume":70,"title":"Internal structure of the fly elementary motion detector","intvolume":"        70","publication_status":"published","citation":{"mla":"Eichner, Hubert, et al. “Internal Structure of the Fly Elementary Motion Detector.” <i>Neuron</i>, vol. 70, no. 6, Elsevier, 2011, pp. 1155–64, doi:<a href=\"https://doi.org/10.1016/j.neuron.2011.03.028\">10.1016/j.neuron.2011.03.028</a>.","ama":"Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. Internal structure of the fly elementary motion detector. <i>Neuron</i>. 2011;70(6):1155-1164. doi:<a href=\"https://doi.org/10.1016/j.neuron.2011.03.028\">10.1016/j.neuron.2011.03.028</a>","chicago":"Eichner, Hubert, Maximilian A Jösch, Bettina Schnell, Dierk Reiff, and Alexander Borst. “Internal Structure of the Fly Elementary Motion Detector.” <i>Neuron</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.neuron.2011.03.028\">https://doi.org/10.1016/j.neuron.2011.03.028</a>.","ista":"Eichner H, Jösch MA, Schnell B, Reiff D, Borst A. 2011. Internal structure of the fly elementary motion detector. Neuron. 70(6), 1155–1164.","apa":"Eichner, H., Jösch, M. A., Schnell, B., Reiff, D., &#38; Borst, A. (2011). Internal structure of the fly elementary motion detector. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2011.03.028\">https://doi.org/10.1016/j.neuron.2011.03.028</a>","short":"H. Eichner, M.A. Jösch, B. Schnell, D. Reiff, A. Borst, Neuron 70 (2011) 1155–1164.","ieee":"H. Eichner, M. A. Jösch, B. Schnell, D. Reiff, and A. Borst, “Internal structure of the fly elementary motion detector,” <i>Neuron</i>, vol. 70, no. 6. Elsevier, pp. 1155–1164, 2011."},"publication":"Neuron","day":"23","author":[{"full_name":"Eichner, Hubert","last_name":"Eichner","first_name":"Hubert"},{"last_name":"Jösch","full_name":"Maximilian Jösch","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","first_name":"Maximilian A","orcid":"0000-0002-3937-1330"},{"full_name":"Schnell, Bettina","last_name":"Schnell","first_name":"Bettina"},{"first_name":"Dierk","full_name":"Reiff, Dierk F","last_name":"Reiff"},{"first_name":"Alexander","last_name":"Borst","full_name":"Borst, Alexander"}],"abstract":[{"text":"Recent experiments have shown that motion detection in Drosophila starts with splitting the visual input into two parallel channels encoding brightness increments (ON) or decrements (OFF). This suggests the existence of either two (ON-ON, OFF-OFF) or four (for all pairwise interactions) separate motion detectors. To decide between these possibilities, we stimulated flies using sequences of ON and OFF brightness pulses while recording from motion-sensitive tangential cells. We found direction-selective responses to sequences of same sign (ON-ON, OFF-OFF), but not of opposite sign (ON-OFF, OFF-ON), refuting the existence of four separate detectors. Based on further measurements, we propose a model that reproduces a variety of additional experimental data sets, including ones that were previously interpreted as support for four separate detectors. Our experiments and the derived model mark an important step in guiding further dissection of the fly motion detection circuit.","lang":"eng"}],"page":"1155 - 1164","status":"public","year":"2011"},{"type":"book_chapter","date_updated":"2021-01-12T06:55:17Z","_id":"2098","publisher":"Science Direct","date_created":"2018-12-11T11:55:42Z","date_published":"2011-01-01T00:00:00Z","quality_controlled":0,"doi":"10.1016/B978-0-12-384988-5.00027-9","extern":1,"month":"01","publist_id":"4935","title":"From sparse mocap to highly detailed facial animation","day":"01","publication":"GPU Computing Gems Emerald Edition","publication_status":"published","citation":{"ama":"Bickel B, Lang M. From sparse mocap to highly detailed facial animation. In: <i>GPU Computing Gems Emerald Edition</i>. Science Direct; 2011:413-426. doi:<a href=\"https://doi.org/10.1016/B978-0-12-384988-5.00027-9\">10.1016/B978-0-12-384988-5.00027-9</a>","chicago":"Bickel, Bernd, and Manuel Lang. “From Sparse Mocap to Highly Detailed Facial Animation.” In <i>GPU Computing Gems Emerald Edition</i>, 413–26. Science Direct, 2011. <a href=\"https://doi.org/10.1016/B978-0-12-384988-5.00027-9\">https://doi.org/10.1016/B978-0-12-384988-5.00027-9</a>.","mla":"Bickel, Bernd, and Manuel Lang. “From Sparse Mocap to Highly Detailed Facial Animation.” <i>GPU Computing Gems Emerald Edition</i>, Science Direct, 2011, pp. 413–26, doi:<a href=\"https://doi.org/10.1016/B978-0-12-384988-5.00027-9\">10.1016/B978-0-12-384988-5.00027-9</a>.","short":"B. Bickel, M. Lang, in:, GPU Computing Gems Emerald Edition, Science Direct, 2011, pp. 413–426.","ieee":"B. Bickel and M. Lang, “From sparse mocap to highly detailed facial animation,” in <i>GPU Computing Gems Emerald Edition</i>, Science Direct, 2011, pp. 413–426.","apa":"Bickel, B., &#38; Lang, M. (2011). From sparse mocap to highly detailed facial animation. In <i>GPU Computing Gems Emerald Edition</i> (pp. 413–426). Science Direct. <a href=\"https://doi.org/10.1016/B978-0-12-384988-5.00027-9\">https://doi.org/10.1016/B978-0-12-384988-5.00027-9</a>","ista":"Bickel B, Lang M. 2011.From sparse mocap to highly detailed facial animation. In: GPU Computing Gems Emerald Edition. , 413–426."},"author":[{"last_name":"Bickel","full_name":"Bernd Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","first_name":"Bernd","orcid":"0000-0001-6511-9385"},{"last_name":"Lang","full_name":"Lang, Manuel","first_name":"Manuel"}],"status":"public","abstract":[{"lang":"eng","text":"This chapter presents a method for real-time animation of highly detailed facial expressions based on sparse motion captures data and a limited set of static example poses. The method for real-time animation of highly detailed facial expressions decomposes geometry into large-scale motion and fine-scale details, such as expression wrinkles. Both large- and fine-scale deformation algorithms run entirely on the GPU, and our implementation based on CUDA achieves an overall performance of about 30 fps. The face conveys the most relevant visual characteristics of human identity and expression. Hence, realistic facial animations or interactions with virtual avatars are important for storytelling and gameplay. However, current approaches are either computationally expensive, require very specialized capture hardware, or are extremely labor intensive. At runtime, given an arbitrary facial expression, the algorithm computes the skin strain from the relative distance between marker points and derives fine-scale corrections for the largescale deformation. During gameplay only the sparse set of marker-point positions is transmitted to the GPU. The face animation is entirely computed on the GPU where the resulting mesh can directly be used as input for the rendering stages. This data can be easily obtained by traditional capture hardware. The proposed in-game algorithm is fast. It also is easy to implement and maps well onto programmable GPUs."}],"page":"413 - 426","year":"2011"},{"date_published":"2011-07-01T00:00:00Z","quality_controlled":0,"publisher":"ACM","date_created":"2018-12-11T11:55:42Z","_id":"2099","date_updated":"2021-01-12T06:55:17Z","issue":"4","type":"journal_article","intvolume":"        30","title":"High-quality passive facial performance capture using anchor frames","publist_id":"4936","volume":30,"extern":1,"month":"07","doi":"10.1145/2010324.1964970","author":[{"full_name":"Beeler, Thabo","last_name":"Beeler","first_name":"Thabo"},{"first_name":"Fabian","last_name":"Hahn","full_name":"Hahn, Fabian"},{"last_name":"Bradley","full_name":"Bradley, Derek J","first_name":"Derek"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","first_name":"Bernd","orcid":"0000-0001-6511-9385","last_name":"Bickel","full_name":"Bernd Bickel"},{"last_name":"Beardsley","full_name":"Beardsley, Paul A","first_name":"Paul"},{"full_name":"Gotsman, Craig","last_name":"Gotsman","first_name":"Craig"},{"first_name":"Robert","last_name":"Sumner","full_name":"Sumner, Robert W"},{"full_name":"Groß, Markus S","last_name":"Groß","first_name":"Markus"}],"citation":{"ieee":"T. Beeler <i>et al.</i>, “High-quality passive facial performance capture using anchor frames,” <i>ACM Transactions on Graphics</i>, vol. 30, no. 4. ACM, 2011.","short":"T. Beeler, F. Hahn, D. Bradley, B. Bickel, P. Beardsley, C. Gotsman, R. Sumner, M. Groß, ACM Transactions on Graphics 30 (2011).","apa":"Beeler, T., Hahn, F., Bradley, D., Bickel, B., Beardsley, P., Gotsman, C., … Groß, M. (2011). High-quality passive facial performance capture using anchor frames. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2010324.1964970\">https://doi.org/10.1145/2010324.1964970</a>","ista":"Beeler T, Hahn F, Bradley D, Bickel B, Beardsley P, Gotsman C, Sumner R, Groß M. 2011. High-quality passive facial performance capture using anchor frames. ACM Transactions on Graphics. 30(4).","ama":"Beeler T, Hahn F, Bradley D, et al. High-quality passive facial performance capture using anchor frames. <i>ACM Transactions on Graphics</i>. 2011;30(4). doi:<a href=\"https://doi.org/10.1145/2010324.1964970\">10.1145/2010324.1964970</a>","chicago":"Beeler, Thabo, Fabian Hahn, Derek Bradley, Bernd Bickel, Paul Beardsley, Craig Gotsman, Robert Sumner, and Markus Groß. “High-Quality Passive Facial Performance Capture Using Anchor Frames.” <i>ACM Transactions on Graphics</i>. ACM, 2011. <a href=\"https://doi.org/10.1145/2010324.1964970\">https://doi.org/10.1145/2010324.1964970</a>.","mla":"Beeler, Thabo, et al. “High-Quality Passive Facial Performance Capture Using Anchor Frames.” <i>ACM Transactions on Graphics</i>, vol. 30, no. 4, ACM, 2011, doi:<a href=\"https://doi.org/10.1145/2010324.1964970\">10.1145/2010324.1964970</a>."},"publication_status":"published","publication":"ACM Transactions on Graphics","day":"01","year":"2011","abstract":[{"lang":"eng","text":"We present a new technique for passive and markerless facial performance capture based on anchor frames. Our method starts with high resolution per-frame geometry acquisition using state-of-theart stereo reconstruction, and proceeds to establish a single triangle mesh that is propagated through the entire performance. Leveraging the fact that facial performances often contain repetitive subsequences, we identify anchor frames as those which contain similar facial expressions to a manually chosen reference expression. Anchor frames are automatically computed over one or even multiple performances. We introduce a robust image-space tracking method that computes pixel matches directly from the reference frame to all anchor frames, and thereby to the remaining frames in the sequence via sequential matching. This allows us to propagate one reconstructed frame to an entire sequence in parallel, in contrast to previous sequential methods. Our anchored reconstruction approach also limits tracker drift and robustly handles occlusions and motion blur. The parallel tracking and mesh propagation offer low computation times. Our technique will even automatically match anchor frames across different sequences captured on different occasions, propagating a single mesh to all performances."}],"status":"public"},{"day":"01","citation":{"short":"J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, M. Alexa, in:, ACM, 2011.","ieee":"J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, and M. Alexa, “Throwable panoramic ball camera,” presented at the SIGGRAPH Asia, 2011.","ista":"Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. 2011. Throwable panoramic ball camera. SIGGRAPH Asia.","apa":"Pfeil, J., Hildebrand, K., Gremzow, C., Bickel, B., &#38; Alexa, M. (2011). Throwable panoramic ball camera. Presented at the SIGGRAPH Asia, ACM. <a href=\"https://doi.org/10.1145/2073370.2073373\">https://doi.org/10.1145/2073370.2073373</a>","ama":"Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. Throwable panoramic ball camera. In: ACM; 2011. doi:<a href=\"https://doi.org/10.1145/2073370.2073373\">10.1145/2073370.2073373</a>","chicago":"Pfeil, Jonas, Kristian Hildebrand, Carsten Gremzow, Bernd Bickel, and Marc Alexa. “Throwable Panoramic Ball Camera.” ACM, 2011. <a href=\"https://doi.org/10.1145/2073370.2073373\">https://doi.org/10.1145/2073370.2073373</a>.","mla":"Pfeil, Jonas, et al. <i>Throwable Panoramic Ball Camera</i>. ACM, 2011, doi:<a href=\"https://doi.org/10.1145/2073370.2073373\">10.1145/2073370.2073373</a>."},"publication_status":"published","author":[{"full_name":"Pfeil, Jonas","last_name":"Pfeil","first_name":"Jonas"},{"full_name":"Hildebrand, Kristian","last_name":"Hildebrand","first_name":"Kristian"},{"full_name":"Gremzow, Carsten","last_name":"Gremzow","first_name":"Carsten"},{"last_name":"Bickel","full_name":"Bernd Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6511-9385","first_name":"Bernd"},{"first_name":"Marc","full_name":"Alexa, Marc","last_name":"Alexa"}],"status":"public","abstract":[{"text":"Acquiring panoramic images using stitching takes a lot of time and moving objects may cause ghosting. It is also difficult to obtain a full spherical panorama, because the downward picture cannot be captured while the camera is mounted on the tripod.","lang":"eng"}],"year":"2011","conference":{"name":"SIGGRAPH Asia"},"date_updated":"2021-01-12T06:55:19Z","type":"conference","_id":"2100","date_created":"2018-12-11T11:55:43Z","publisher":"ACM","quality_controlled":0,"date_published":"2011-12-01T00:00:00Z","month":"12","extern":1,"doi":"10.1145/2073370.2073373","publist_id":"4934","title":"Throwable panoramic ball camera"},{"status":"public","abstract":[{"lang":"eng","text":"The crystal structure of the decamer sequence d(CGGGTACCCG)4 as a four-way Holliday junction has been determined at 2.35 Å resolution. The sequence was designed in order to understand the principles that govern the relationship between sequence and branching structure. It crystallized as a four-way junction structure with an overall geometry similar to those of previously determined Holliday junction structures."}],"day":"01","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1107/s1744309111046616","article_type":"original","has_accepted_license":"1","issue":"12","type":"journal_article","publisher":"International Union of Crystallography","date_created":"2026-01-29T22:06:25Z","quality_controlled":"1","date_published":"2011-12-01T00:00:00Z","oa_version":"None","page":"1506-1510","year":"2011","article_processing_charge":"No","publication":"Acta Crystallographica Section F Structural Biology Communications","citation":{"ieee":"P. K. Mandal, S. Venkadesh, and N. Gautham, “Structure of d(CGGGTACCCG)4 as a four-way Holliday junction,” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 67, no. 12. International Union of Crystallography, pp. 1506–1510, 2011.","short":"P.K. Mandal, S. Venkadesh, N. Gautham, Acta Crystallographica Section F Structural Biology Communications 67 (2011) 1506–1510.","apa":"Mandal, P. K., Venkadesh, S., &#38; Gautham, N. (2011). Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/s1744309111046616\">https://doi.org/10.1107/s1744309111046616</a>","ista":"Mandal PK, Venkadesh S, Gautham N. 2011. Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. Acta Crystallographica Section F Structural Biology Communications. 67(12), 1506–1510.","ama":"Mandal PK, Venkadesh S, Gautham N. Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. <i>Acta Crystallographica Section F Structural Biology Communications</i>. 2011;67(12):1506-1510. doi:<a href=\"https://doi.org/10.1107/s1744309111046616\">10.1107/s1744309111046616</a>","chicago":"Mandal, Pradeep K, S. Venkadesh, and N. Gautham. “Structure of d(CGGGTACCCG)4 as a Four-Way Holliday Junction.” <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography, 2011. <a href=\"https://doi.org/10.1107/s1744309111046616\">https://doi.org/10.1107/s1744309111046616</a>.","mla":"Mandal, Pradeep K., et al. “Structure of d(CGGGTACCCG)4 as a Four-Way Holliday Junction.” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 67, no. 12, International Union of Crystallography, 2011, pp. 1506–10, doi:<a href=\"https://doi.org/10.1107/s1744309111046616\">10.1107/s1744309111046616</a>."},"publication_status":"published","author":[{"full_name":"Mandal, Pradeep K","last_name":"Mandal","orcid":"0000-0001-5996-956X","first_name":"Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3"},{"first_name":"S.","last_name":"Venkadesh","full_name":"Venkadesh, S."},{"first_name":"N.","full_name":"Gautham, N.","last_name":"Gautham"}],"publication_identifier":{"issn":["1744-3091"]},"language":[{"iso":"eng"}],"volume":67,"month":"12","intvolume":"        67","title":"Structure of d(CGGGTACCCG)4 as a four-way Holliday junction","date_updated":"2026-02-23T08:59:44Z","_id":"21107","OA_type":"closed access"},{"intvolume":"       407","title":"The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice","month":"04","volume":407,"oa":1,"external_id":{"pmid":["21419105"]},"pmid":1,"OA_type":"free access","date_updated":"2026-02-20T09:11:23Z","_id":"21108","year":"2011","article_processing_charge":"No","oa_version":"Published Version","page":"548-551","author":[{"first_name":"S.","full_name":"Venkadesh, S.","last_name":"Venkadesh"},{"orcid":"0000-0001-5996-956X","first_name":"Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","full_name":"Mandal, Pradeep K","last_name":"Mandal"},{"full_name":"Gautham, N.","last_name":"Gautham","first_name":"N."}],"publication_identifier":{"issn":["0006-291X"]},"language":[{"iso":"eng"}],"publication":"Biochemical and Biophysical Research Communications","citation":{"chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">https://doi.org/10.1016/j.bbrc.2011.03.056</a>.","ama":"Venkadesh S, Mandal PK, Gautham N. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research Communications</i>. 2011;407(3):548-551. doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">10.1016/j.bbrc.2011.03.056</a>","mla":"Venkadesh, S., et al. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 3, Elsevier, 2011, pp. 548–51, doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">10.1016/j.bbrc.2011.03.056</a>.","short":"S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research Communications 407 (2011) 548–551.","ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice,” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 3. Elsevier, pp. 548–551, 2011.","ista":"Venkadesh S, Mandal PK, Gautham N. 2011. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. Biochemical and Biophysical Research Communications. 407(3), 548–551.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research Communications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">https://doi.org/10.1016/j.bbrc.2011.03.056</a>"},"publication_status":"published","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1016/j.bbrc.2011.03.056","article_type":"original","has_accepted_license":"1","publisher":"Elsevier","date_created":"2026-01-29T22:09:20Z","date_published":"2011-04-15T00:00:00Z","quality_controlled":"1","issue":"3","type":"journal_article","status":"public","abstract":[{"text":"We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson–Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5 Å. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry.","lang":"eng"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.bbrc.2011.03.056","open_access":"1"}],"day":"15"},{"day":"08","status":"public","abstract":[{"text":"We report the 2.6 Å resolution crystal structure of the tetra-decamer d(CGCGGGTACCCGCG) in the tetragonal space group P43. This sequence contains the KpnI restriction site GGTACC in the centre which is flanked by alternating ‘CG’ sequences, and has a ‘TA’ step at the centre. These are features could favour the left-handed Z type helix. Despite this, overall the molecule has the A form. This is the first tetra-decamer crystallized in the A-DNA conformation, i.e. more than one full turn of the A helix. The crystallographic asymmetric unit consists of one tetra-decamer duplex. The helical twist and slide, as well as the base pair–base pair stacking interactions show alternations at the alternating pyrimidine–purine and purine–pyrimidine base steps. This variation is reminiscent of the dinucleotide repeat in left-handed Z-DNA helices. The crystal packing is unlike other A-DNA crystal structures, with each helix having a large number of contacts of many different types with symmetry-related neighbours.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.bbrc.2011.03.007"}],"issue":"2","type":"journal_article","date_created":"2026-01-29T22:10:30Z","publisher":"Elsevier","quality_controlled":"1","date_published":"2011-04-08T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","doi":"10.1016/j.bbrc.2011.03.007","article_type":"original","has_accepted_license":"1","publication":"Biochemical and Biophysical Research Communications","citation":{"ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2,” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2. Elsevier, pp. 307–312, 2011.","short":"S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research Communications 407 (2011) 307–312.","ista":"Venkadesh S, Mandal PK, Gautham N. 2011. The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. Biochemical and Biophysical Research Communications. 407(2), 307–312.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">https://doi.org/10.1016/j.bbrc.2011.03.007</a>","chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research Communications</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">https://doi.org/10.1016/j.bbrc.2011.03.007</a>.","ama":"Venkadesh S, Mandal PK, Gautham N. The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>. 2011;407(2):307-312. doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">10.1016/j.bbrc.2011.03.007</a>","mla":"Venkadesh, S., et al. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2, Elsevier, 2011, pp. 307–12, doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">10.1016/j.bbrc.2011.03.007</a>."},"publication_status":"published","author":[{"first_name":"S.","last_name":"Venkadesh","full_name":"Venkadesh, S."},{"last_name":"Mandal","full_name":"Mandal, Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K","orcid":"0000-0001-5996-956X"},{"first_name":"N.","full_name":"Gautham, N.","last_name":"Gautham"}],"publication_identifier":{"issn":["0006-291X"]},"language":[{"iso":"eng"}],"oa_version":"None","page":"307-312","year":"2011","article_processing_charge":"No","date_updated":"2026-02-20T09:01:51Z","_id":"21109","pmid":1,"OA_type":"free access","volume":407,"month":"04","oa":1,"external_id":{"pmid":["21397589"]},"intvolume":"       407","title":"The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2"},{"author":[{"last_name":"Maas","full_name":"Jan Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0845-1338","first_name":"Jan"},{"last_name":"Van Neerven","full_name":"Van Neerven, Jan","first_name":"Jan"}],"publication":"Parabolic Problems","day":"10","publication_status":"published","citation":{"ista":"Maas J, Van Neerven J. 2011.Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In: Parabolic Problems. vol. 80, 463–477.","apa":"Maas, J., &#38; Van Neerven, J. (2011). Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In <i>Parabolic Problems</i> (Vol. 80, pp. 463–477). Birkhäuser. <a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">https://doi.org/10.1007/978-3-0348-0075-4_24</a>","short":"J. Maas, J. Van Neerven, in:, Parabolic Problems, Birkhäuser, 2011, pp. 463–477.","ieee":"J. Maas and J. Van Neerven, “Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators,” in <i>Parabolic Problems</i>, vol. 80, Birkhäuser, 2011, pp. 463–477.","mla":"Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification for Analytic Ornstein-Uhlenbeck Operators.” <i>Parabolic Problems</i>, vol. 80, Birkhäuser, 2011, pp. 463–77, doi:<a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">10.1007/978-3-0348-0075-4_24</a>.","chicago":"Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification for Analytic Ornstein-Uhlenbeck Operators.” In <i>Parabolic Problems</i>, 80:463–77. Birkhäuser, 2011. <a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">https://doi.org/10.1007/978-3-0348-0075-4_24</a>.","ama":"Maas J, Van Neerven J. Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In: <i>Parabolic Problems</i>. Vol 80. Birkhäuser; 2011:463-477. doi:<a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">10.1007/978-3-0348-0075-4_24</a>"},"year":"2011","status":"public","page":"463 - 477","abstract":[{"lang":"eng","text":"Let P be the Ornstein-Uhlenbeck semigroup associated with the stochastic Cauchy problem  dU(t)=AU(t)dt+dWH(t), where A is the generator of a C 0-semigroup S on a Banach space E, H is a Hilbert subspace of E, and W H is an H-cylindrical Brownian motion. Assuming that S restricts to a C 0-semigroup on H, we obtain L p -bounds for D H P(t). We show that if P is analytic, then the invariance assumption is fulfilled. As an application we determine the L p -domain of the generator of P explicitly in the case where S restricts to a C 0-semigroup on H which is similar to an analytic contraction semigroup. The results are applied to the 1D stochastic heat equation driven by additive space-time white noise."}],"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0911.4336 "}],"date_created":"2018-12-11T11:55:48Z","acknowledgement":"The authors are supported by VIDI subsidy 639.032.201 (JM) and VICI subsidy 639.033.604 (JvN) of the Netherlands Organisation for Scientific Research (NWO). ","publisher":"Birkhäuser","quality_controlled":0,"date_published":"2011-06-10T00:00:00Z","type":"book_chapter","date_updated":"2021-01-12T06:55:24Z","_id":"2116","title":"Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators","intvolume":"        80","oa":1,"doi":"10.1007/978-3-0348-0075-4_24","extern":1,"volume":80,"month":"06","publist_id":"4918"},{"year":"2011","abstract":[{"lang":"eng","text":"We study, in L1(R̃n; γ) with respect to the gaussian measure, non- tangential maximal functions and conical square functions associ- ated with the Ornstein-Uhlenbeck operator by developing a set of techniques which allow us, to some extent, to compensate for the non-doubling character of the gaussian measure. The main result asserts that conical square functions can be controlled in L1-norm by non-tangential maximal functions. Along the way we prove a change of aperture result for the latter. This complements recent results on gaussian Hardy spaces due to Mauceri and Meda."}],"page":"313 - 341","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1003.4092"}],"status":"public","author":[{"orcid":"0000-0002-0845-1338","first_name":"Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Jan Maas","last_name":"Maas"},{"full_name":"van Neerven, Jan M","last_name":"Van Neerven","first_name":"Jan"},{"full_name":"Portal, Pierre","last_name":"Portal","first_name":"Pierre"}],"publication_status":"published","citation":{"mla":"Maas, Jan, et al. “Conical Square Functions and Non-Tangential Maximal Functions with Respect to the Gaussian Measure.” <i>Publicacions Matemàtiques</i>, vol. 55, no. 2, Universitat Autònoma de Barcelona, Departament de Matemàtique, 2011, pp. 313–41, doi:<a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">10.5565/PUBLMAT_55211_03  </a>.","chicago":"Maas, Jan, Jan Van Neerven, and Pierre Portal. “Conical Square Functions and Non-Tangential Maximal Functions with Respect to the Gaussian Measure.” <i>Publicacions Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique, 2011. <a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">https://doi.org/10.5565/PUBLMAT_55211_03  </a>.","ama":"Maas J, Van Neerven J, Portal P. Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. <i>Publicacions Matemàtiques</i>. 2011;55(2):313-341. doi:<a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">10.5565/PUBLMAT_55211_03  </a>","apa":"Maas, J., Van Neerven, J., &#38; Portal, P. (2011). Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. <i>Publicacions Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique. <a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">https://doi.org/10.5565/PUBLMAT_55211_03  </a>","ista":"Maas J, Van Neerven J, Portal P. 2011. Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. Publicacions Matemàtiques. 55(2), 313–341.","ieee":"J. Maas, J. Van Neerven, and P. Portal, “Conical square functions and non-tangential maximal functions with respect to the Gaussian measure,” <i>Publicacions Matemàtiques</i>, vol. 55, no. 2. Universitat Autònoma de Barcelona, Departament de Matemàtique, pp. 313–341, 2011.","short":"J. Maas, J. Van Neerven, P. Portal, Publicacions Matemàtiques 55 (2011) 313–341."},"day":"01","publication":"Publicacions Matemàtiques","title":"Conical square functions and non-tangential maximal functions with respect to the Gaussian measure","intvolume":"        55","publist_id":"4910","doi":"10.5565/PUBLMAT_55211_03\t ","oa":1,"month":"07","volume":55,"extern":1,"quality_controlled":0,"date_published":"2011-07-01T00:00:00Z","publisher":"Universitat Autònoma de Barcelona, Departament de Matemàtique","date_created":"2018-12-11T11:55:50Z","acknowledgement":"The first named author is supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO). The second named author is supported by VICI subsidy 639.033.604 of the Netherlands Organisation for Scientific Research (NWO","_id":"2122","type":"journal_article","date_updated":"2021-01-12T06:55:26Z","issue":"2"},{"doi":"10.1007/s00028-010-0096-5","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","extern":"1","publist_id":"4911","date_created":"2018-12-11T11:55:51Z","publisher":"Birkhäuser","date_published":"2011-01-21T00:00:00Z","type":"journal_article","issue":"2","status":"public","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1005.0998"}],"abstract":[{"lang":"eng","text":"We prove a Trotter product formula for gradient flows in metric spaces. This result is applied to establish convergence in the L 2-Wasserstein metric of the splitting method for some Fokker-Planck equations and porous medium type equations perturbed by a potential."}],"day":"21","title":"A Trotter product formula for gradient flows in metric spaces","intvolume":"        11","oa":1,"month":"01","volume":11,"acknowledgement":"The second named author is supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO).","related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1007/s00028-012-0173-z"}]},"date_updated":"2021-11-16T08:05:46Z","_id":"2123","year":"2011","article_processing_charge":"No","oa_version":"None","page":"405 - 427","author":[{"last_name":"Clément","full_name":"Clément, Philippe","first_name":"Philippe"},{"orcid":"0000-0002-0845-1338","first_name":"Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan","last_name":"Maas"}],"language":[{"iso":"eng"}],"publication":"Journal of Evolution Equations","publication_status":"published","citation":{"chicago":"Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient Flows in Metric Spaces.” <i>Journal of Evolution Equations</i>. Birkhäuser, 2011. <a href=\"https://doi.org/10.1007/s00028-010-0096-5\">https://doi.org/10.1007/s00028-010-0096-5</a>.","ama":"Clément P, Maas J. A Trotter product formula for gradient flows in metric spaces. <i>Journal of Evolution Equations</i>. 2011;11(2):405-427. doi:<a href=\"https://doi.org/10.1007/s00028-010-0096-5\">10.1007/s00028-010-0096-5</a>","mla":"Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient Flows in Metric Spaces.” <i>Journal of Evolution Equations</i>, vol. 11, no. 2, Birkhäuser, 2011, pp. 405–27, doi:<a href=\"https://doi.org/10.1007/s00028-010-0096-5\">10.1007/s00028-010-0096-5</a>.","ieee":"P. Clément and J. Maas, “A Trotter product formula for gradient flows in metric spaces,” <i>Journal of Evolution Equations</i>, vol. 11, no. 2. Birkhäuser, pp. 405–427, 2011.","short":"P. Clément, J. Maas, Journal of Evolution Equations 11 (2011) 405–427.","ista":"Clément P, Maas J. 2011. A Trotter product formula for gradient flows in metric spaces. Journal of Evolution Equations. 11(2), 405–427.","apa":"Clément, P., &#38; Maas, J. (2011). A Trotter product formula for gradient flows in metric spaces. <i>Journal of Evolution Equations</i>. Birkhäuser. <a href=\"https://doi.org/10.1007/s00028-010-0096-5\">https://doi.org/10.1007/s00028-010-0096-5</a>"}},{"type":"journal_article","issue":"8","date_updated":"2021-01-12T06:55:28Z","_id":"2126","publisher":"Academic Press","date_created":"2018-12-11T11:55:51Z","acknowledgement":"Supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO)","date_published":"2011-03-04T00:00:00Z","quality_controlled":0,"doi":"10.1016/j.jfa.2011.06.009 ","oa":1,"extern":1,"month":"03","volume":261,"publist_id":"4909","title":"Gradient flows of the entropy for finite Markov chains","intvolume":"       261","day":"04","publication":"Journal of Functional Analysis","publication_status":"published","citation":{"ista":"Maas J. 2011. Gradient flows of the entropy for finite Markov chains. Journal of Functional Analysis. 261(8), 2250–2292.","apa":"Maas, J. (2011). Gradient flows of the entropy for finite Markov chains. <i>Journal of Functional Analysis</i>. Academic Press. <a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">https://doi.org/10.1016/j.jfa.2011.06.009 </a>","short":"J. Maas, Journal of Functional Analysis 261 (2011) 2250–2292.","ieee":"J. Maas, “Gradient flows of the entropy for finite Markov chains,” <i>Journal of Functional Analysis</i>, vol. 261, no. 8. Academic Press, pp. 2250–2292, 2011.","mla":"Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal of Functional Analysis</i>, vol. 261, no. 8, Academic Press, 2011, pp. 2250–92, doi:<a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">10.1016/j.jfa.2011.06.009 </a>.","ama":"Maas J. Gradient flows of the entropy for finite Markov chains. <i>Journal of Functional Analysis</i>. 2011;261(8):2250-2292. doi:<a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">10.1016/j.jfa.2011.06.009 </a>","chicago":"Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal of Functional Analysis</i>. Academic Press, 2011. <a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">https://doi.org/10.1016/j.jfa.2011.06.009 </a>."},"author":[{"full_name":"Jan Maas","last_name":"Maas","first_name":"Jan","orcid":"0000-0002-0845-1338","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87"}],"status":"public","page":"2250 - 2292","abstract":[{"text":"Let K be an irreducible and reversible Markov kernel on a finite set X. We construct a metric W on the set of probability measures on X and show that with respect to this metric, the law of the continuous time Markov chain evolves as the gradient flow of the entropy. This result is a discrete counterpart of the Wasserstein gradient flow interpretation of the heat flow in Rn by Jordan, Kinderlehrer and Otto (1998). The metric W is similar to, but different from, the L2-Wasserstein metric, and is defined via a discrete variant of the Benamou–Brenier formula.\n","lang":"eng"}],"main_file_link":[{"url":"http://arxiv.org/abs/1102.5238","open_access":"1"}],"year":"2011"},{"extern":1,"month":"05","oa":1,"publist_id":"4886","title":"Controlling a diatomic shape resonance with non-resonant light","date_updated":"2021-01-12T06:55:32Z","type":"preprint","_id":"2138","publisher":"ArXiv","date_created":"2018-12-11T11:55:55Z","acknowledgement":"Financial support from the Deutsche Forschungsgemeinschaft (Grant No. KO 2301/2), by the Spanish project FIS2008-02380 (MICINN) as well as the Grants FQM-2445 and FQM-4643 (Junta de Andaluc´ıa), Campus de Excelencia Internacional Proyecto GENIL CEB09-0010","quality_controlled":0,"date_published":"2011-05-04T00:00:00Z","status":"public","main_file_link":[{"url":"http://arxiv.org/abs/1105.0761","open_access":"1"}],"abstract":[{"text":"A (diatomic) shape resonance is a metastable state of a pair of colliding atoms quasi-bound by the centrifugal barrier imposed by the angular momentum involved in the collision. The temporary trapping of the atoms' scattering wavefunction corresponds to an enhanced atom pair density at low interatomic separations. This leads to larger overlap of the wavefunctions involved in a molecule formation process such as photoassociation, rendering the process more efficient. However, for an ensemble of atoms, the atom pair density will only be enhanced if the energy of the resonance comes close to the temperature of the atomic ensemble. Herein we explore the possibility of controlling the energy of a shape resonance by shifting it toward the temperature of atoms confined in a trap. The shifts are imparted by the interaction of non-resonant light with the anisotropic polarizability of the atom pair, which affects both the centrifugal barrier and the pair's rotational and vibrational levels. We find that at laser intensities of up to 5×109 W/cm2 the pair density is increased by one order of magnitude for 87Rb atoms at 100μK and by two orders of magnitude for 88Sr atoms at 20μK.","lang":"eng"}],"year":"2011","publication":"Unknown","day":"04","citation":{"ista":"Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. 2011. Controlling a diatomic shape resonance with non-resonant light. Unknown, .","apa":"Ağanoğlu, R., Lemeshko, M., Friedrich, B., González Férez, R., &#38; Koch, C. (2011). Controlling a diatomic shape resonance with non-resonant light. <i>Unknown</i>. ArXiv.","ieee":"R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, and C. Koch, “Controlling a diatomic shape resonance with non-resonant light,” <i>Unknown</i>. ArXiv, 2011.","short":"R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, C. Koch, Unknown (2011).","mla":"Ağanoğlu, Ruzin, et al. “Controlling a Diatomic Shape Resonance with Non-Resonant Light.” <i>Unknown</i>, ArXiv, 2011.","chicago":"Ağanoğlu, Ruzin, Mikhail Lemeshko, Břetislav Friedrich, Rosario González Férez, and Christiane Koch. “Controlling a Diatomic Shape Resonance with Non-Resonant Light.” <i>Unknown</i>. ArXiv, 2011.","ama":"Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. Controlling a diatomic shape resonance with non-resonant light. <i>Unknown</i>. 2011."},"publication_status":"published","author":[{"first_name":"Ruzin","last_name":"Ağanoğlu","full_name":"Ağanoğlu, Ruzin"},{"full_name":"Mikhail Lemeshko","last_name":"Lemeshko","first_name":"Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Břetislav","last_name":"Friedrich","full_name":"Friedrich, Břetislav"},{"last_name":"González Férez","full_name":"González-Férez, Rosario","first_name":"Rosario"},{"last_name":"Koch","full_name":"Koch, Christiane P","first_name":"Christiane"}]},{"year":"2011","abstract":[{"lang":"eng","text":"We show that dressing polar molecules with a far-off-resonant optical field leads to new types of intermolecular potentials, which undergo a crossover from the inverse power to oscillating behavior depending on the intermolecular distance, and whose parameters can be tuned by varying the laser intensity and wavelength. We present analytic expressions for the potential energy surfaces, thereby providing direct access to the parameters of an optical field required to design intermolecular interactions experimentally."}],"main_file_link":[{"url":"http://arxiv.org/abs/1104.1046","open_access":"1"}],"status":"public","author":[{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","first_name":"Mikhail","last_name":"Lemeshko","full_name":"Mikhail Lemeshko"}],"publication_status":"published","citation":{"ama":"Lemeshko M. Shaping interactions between polar molecules with far-off-resonant light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. 2011;83(5). doi:<a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">10.1103/PhysRevA.83.051402</a>","chicago":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society, 2011. <a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">https://doi.org/10.1103/PhysRevA.83.051402</a>.","mla":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 83, no. 5, American Physical Society, 2011, doi:<a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">10.1103/PhysRevA.83.051402</a>.","ieee":"M. Lemeshko, “Shaping interactions between polar molecules with far-off-resonant light,” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 83, no. 5. American Physical Society, 2011.","short":"M. Lemeshko, Physical Review A - Atomic, Molecular, and Optical Physics 83 (2011).","apa":"Lemeshko, M. (2011). Shaping interactions between polar molecules with far-off-resonant light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">https://doi.org/10.1103/PhysRevA.83.051402</a>","ista":"Lemeshko M. 2011. Shaping interactions between polar molecules with far-off-resonant light. Physical Review A - Atomic, Molecular, and Optical Physics. 83(5)."},"publication":"Physical Review A - Atomic, Molecular, and Optical Physics","day":"27","title":"Shaping interactions between polar molecules with far-off-resonant light","intvolume":"        83","publist_id":"4775","doi":"10.1103/PhysRevA.83.051402","oa":1,"extern":1,"volume":83,"month":"05","quality_controlled":0,"date_published":"2011-05-27T00:00:00Z","publisher":"American Physical Society","date_created":"2018-12-11T11:56:17Z","_id":"2198","type":"journal_article","date_updated":"2021-01-12T06:55:55Z","issue":"5"},{"day":"12","keyword":["Multidisciplinary"],"status":"public","main_file_link":[{"url":"https://doi.org/10.1073/pnas.1012668108","open_access":"1"}],"abstract":[{"lang":"eng","text":"Understanding the mechanism of protein folding requires a detailed knowledge of the structural properties of the barriers separating unfolded from native conformations. The S-peptide from ribonuclease S forms its α-helical structure only upon binding to the folded S-protein. We characterized the transition state for this binding-induced folding reaction at high resolution by determining the effect of site-specific backbone thioxylation and side-chain modifications on the kinetics and thermodynamics of the reaction, which allows us to monitor formation of backbone hydrogen bonds and side-chain interactions in the transition state. The experiments reveal that α-helical structure in the S-peptide is absent in the transition state of binding. Recognition between the unfolded S-peptide and the S-protein is mediated by loosely packed hydrophobic side-chain interactions in two well defined regions on the S-peptide. Close packing and helix formation occurs rapidly after binding. Introducing hydrophobic residues at positions outside the recognition region can drastically slow down association."}],"type":"journal_article","issue":"10","publisher":"Proceedings of the National Academy of Sciences","date_created":"2023-09-06T12:54:36Z","scopus_import":"1","quality_controlled":"1","date_published":"2011-01-12T00:00:00Z","doi":"10.1073/pnas.1012668108","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","article_type":"original","publication":"PNAS","publication_status":"published","citation":{"ama":"Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. <i>PNAS</i>. 2011;108(10):3952-3957. doi:<a href=\"https://doi.org/10.1073/pnas.1012668108\">10.1073/pnas.1012668108</a>","chicago":"Bachmann, Annett, Dirk Wildemann, Florian M Praetorius, Gunter Fischer, and Thomas Kiefhaber. “Mapping Backbone and Side-Chain Interactions in the Transition State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>. Proceedings of the National Academy of Sciences, 2011. <a href=\"https://doi.org/10.1073/pnas.1012668108\">https://doi.org/10.1073/pnas.1012668108</a>.","mla":"Bachmann, Annett, et al. “Mapping Backbone and Side-Chain Interactions in the Transition State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>, vol. 108, no. 10, Proceedings of the National Academy of Sciences, 2011, pp. 3952–57, doi:<a href=\"https://doi.org/10.1073/pnas.1012668108\">10.1073/pnas.1012668108</a>.","ieee":"A. Bachmann, D. Wildemann, F. M. Praetorius, G. Fischer, and T. Kiefhaber, “Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction,” <i>PNAS</i>, vol. 108, no. 10. Proceedings of the National Academy of Sciences, pp. 3952–3957, 2011.","short":"A. Bachmann, D. Wildemann, F.M. Praetorius, G. Fischer, T. Kiefhaber, PNAS 108 (2011) 3952–3957.","apa":"Bachmann, A., Wildemann, D., Praetorius, F. M., Fischer, G., &#38; Kiefhaber, T. (2011). Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. <i>PNAS</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1012668108\">https://doi.org/10.1073/pnas.1012668108</a>","ista":"Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. 2011. Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. PNAS. 108(10), 3952–3957."},"author":[{"last_name":"Bachmann","full_name":"Bachmann, Annett","first_name":"Annett"},{"last_name":"Wildemann","full_name":"Wildemann, Dirk","first_name":"Dirk"},{"first_name":"Florian M","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","full_name":"Praetorius, Florian M","last_name":"Praetorius"},{"last_name":"Fischer","full_name":"Fischer, Gunter","first_name":"Gunter"},{"first_name":"Thomas","full_name":"Kiefhaber, Thomas","last_name":"Kiefhaber"}],"language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"oa_version":"Published Version","page":"3952-3957","year":"2011","article_processing_charge":"No","date_updated":"2023-11-07T11:50:29Z","_id":"14305","pmid":1,"oa":1,"month":"01","volume":108,"external_id":{"pmid":["21325613"]},"title":"Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction","intvolume":"       108"},{"abstract":[{"text":"We propose a general conjecture for the mixed Hodge polynomial of the generic character varieties of representations of the fundamental group of a Riemann surface of genus g to GLn(C) with fixed generic semisimple conjugacy classes at k punctures. This conjecture generalizes the Cauchy identity for Macdonald polynomials and is a common generalization of two formulas that we prove in this paper. The first is a formula for the E-polynomial of these character varieties which we obtain using the character table of GLn(Fq). We use this formula to compute the Euler characteristic of character varieties. The second formula gives the Poincaré polynomial of certain associated quiver varieties which we obtain using the character table of gln(Fq). In the last main result we prove that the Poincaré polynomials of the quiver varieties equal certain multiplicities in the tensor product of irreducible characters of GLn(Fq). As a consequence we find a curious connection between Kac-Moody algebras associated with comet-shaped, and typically wild, quivers and the representation theory of GLn(Fq).","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0810.2076"}],"page":"323 - 400","status":"public","year":"2011","citation":{"ama":"Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on character and quiver varieties. <i>Duke Mathematical Journal</i>. 2011;160(2):323-400. doi:<a href=\"https://doi.org/10.1215/00127094-1444258\">10.1215/00127094-1444258</a>","chicago":"Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” <i>Duke Mathematical Journal</i>. Duke University Press, 2011. <a href=\"https://doi.org/10.1215/00127094-1444258\">https://doi.org/10.1215/00127094-1444258</a>.","mla":"Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” <i>Duke Mathematical Journal</i>, vol. 160, no. 2, Duke University Press, 2011, pp. 323–400, doi:<a href=\"https://doi.org/10.1215/00127094-1444258\">10.1215/00127094-1444258</a>.","short":"T. Hausel, E. Letellier, F. Rodríguez Villegas, Duke Mathematical Journal 160 (2011) 323–400.","ieee":"T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis on character and quiver varieties,” <i>Duke Mathematical Journal</i>, vol. 160, no. 2. Duke University Press, pp. 323–400, 2011.","apa":"Hausel, T., Letellier, E., &#38; Rodríguez Villegas, F. (2011). Arithmetic harmonic analysis on character and quiver varieties. <i>Duke Mathematical Journal</i>. Duke University Press. <a href=\"https://doi.org/10.1215/00127094-1444258\">https://doi.org/10.1215/00127094-1444258</a>","ista":"Hausel T, Letellier E, Rodríguez Villegas F. 2011. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 160(2), 323–400."},"publication_status":"published","day":"01","publication":"Duke Mathematical Journal","author":[{"first_name":"Tamas","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","full_name":"Tamas Hausel","last_name":"Hausel"},{"first_name":"Emmanuel","full_name":"Letellier, Emmanuel","last_name":"Letellier"},{"full_name":"Rodríguez Villegas, Fernando","last_name":"Rodríguez Villegas","first_name":"Fernando"}],"publist_id":"5728","extern":1,"month":"01","volume":160,"oa":1,"doi":"10.1215/00127094-1444258","intvolume":"       160","title":"Arithmetic harmonic analysis on character and quiver varieties","_id":"1467","date_updated":"2021-01-12T06:50:56Z","issue":"2","type":"journal_article","date_published":"2011-01-01T00:00:00Z","quality_controlled":0,"acknowledgement":"Hausel’s work was supported by National Science Foundation grants DMS-0305505 and DMS-0604775, by an Alfred Sloan Fellowship, and by a Royal Society University Research Fellowship. Letellier’s work supported by Agence Nationale de la Recherche grant ANR-09-JCJC-0102-01.\nRodriguez-Villegas’s work supported by National Science Foundation grant DMS-0200605, by an FRA from the University of Texas at Austin, by EPSRC grant EP/G027110/1, by visiting fellowships at All Souls and Wadham Colleges in Oxford, and by a Research Scholarship from the Clay Mathematical Institute.","date_created":"2018-12-11T11:52:11Z","publisher":"Duke University Press"},{"citation":{"ieee":"S. Novak, “The number of equilibria in the diallelic Levene model with multiple demes,” <i>Theoretical Population Biology</i>, vol. 79, no. 3. Academic Press, pp. 97–101, 2011.","short":"S. Novak, Theoretical Population Biology 79 (2011) 97–101.","ista":"Novak S. 2011. The number of equilibria in the diallelic Levene model with multiple demes. Theoretical Population Biology. 79(3), 97–101.","apa":"Novak, S. (2011). The number of equilibria in the diallelic Levene model with multiple demes. <i>Theoretical Population Biology</i>. Academic Press. <a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">https://doi.org/10.1016/j.tpb.2010.12.002</a>","ama":"Novak S. The number of equilibria in the diallelic Levene model with multiple demes. <i>Theoretical Population Biology</i>. 2011;79(3):97-101. doi:<a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">10.1016/j.tpb.2010.12.002</a>","chicago":"Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” <i>Theoretical Population Biology</i>. Academic Press, 2011. <a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">https://doi.org/10.1016/j.tpb.2010.12.002</a>.","mla":"Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” <i>Theoretical Population Biology</i>, vol. 79, no. 3, Academic Press, 2011, pp. 97–101, doi:<a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">10.1016/j.tpb.2010.12.002</a>."},"publication_status":"published","publication":"Theoretical Population Biology","day":"01","author":[{"last_name":"Novak","full_name":"Sebastian Novak","id":"461468AE-F248-11E8-B48F-1D18A9856A87","first_name":"Sebastian"}],"abstract":[{"text":"The Levene model is the simplest mathematical model to describe the evolution of gene frequencies in spatially subdivided populations. It provides insight into how locally varying selection promotes a population’s genetic diversity. Despite its simplicity, interesting problems have remained unsolved even in the diallelic case. In this paper we answer an open problem by establishing that for two alleles at one locus and J demes, up to 2J−1 polymorphic equilibria may coexist. We first present a proof for the case of stable monomorphisms and then show that the result also holds for protected alleles. These findings allow us to prove that any odd number (up to 2J−1) of equilibria is possible, before we extend the proof to even numbers. We conclude with some numerical results and show that for J&gt;2, the proportion of parameter space affording this maximum is extremely small.","lang":"eng"}],"page":"97 - 101","status":"public","year":"2011","_id":"1863","date_updated":"2021-01-12T06:53:42Z","issue":"3","type":"journal_article","date_published":"2011-05-01T00:00:00Z","quality_controlled":0,"publisher":"Academic Press","acknowledgement":"FWF 21305","date_created":"2018-12-11T11:54:25Z","publist_id":"5236","month":"05","volume":79,"extern":1,"doi":"10.1016/j.tpb.2010.12.002","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"intvolume":"        79","title":"The number of equilibria in the diallelic Levene model with multiple demes"},{"doi":"10.1038/nature10330","volume":476,"month":"08","extern":1,"publist_id":"5110","title":"Structure of the membrane domain of respiratory complex i","intvolume":"       476","type":"journal_article","issue":"7361","date_updated":"2021-01-12T06:54:26Z","_id":"1973","acknowledgement":"This work was funded by the Medical Research Council.","publisher":"Nature Publishing Group","date_created":"2018-12-11T11:54:59Z","date_published":"2011-08-25T00:00:00Z","quality_controlled":0,"status":"public","abstract":[{"lang":"eng","text":"Complex I is the first and largest enzyme of the respiratory chain, coupling electron transfer between NADH and ubiquinone to the translocation of four protons across the membrane. It has a central role in cellular energy production and has been implicated in many human neurodegenerative diseases. The L-shaped enzyme consists of hydrophilic and membrane domains. Previously, we determined the structure of the hydrophilic domain. Here we report the crystal structure of the Esherichia coli complex I membrane domain at 3.0 Ã. resolution. It includes six subunits, NuoL, NuoM, NuoN, NuoA, NuoJ and NuoK, with 55 transmembrane helices. The fold of the homologous antiporter-like subunits L, M and N is novel, with two inverted structural repeats of five transmembrane helices arranged, unusually, face-to-back. Each repeat includes a discontinuous transmembrane helix and forms half of a channel across the membrane. A network of conserved polar residues connects the two half-channels, completing the proton translocation pathway. Unexpectedly, lysines rather than carboxylate residues act as the main elements of the proton pump in these subunits. The fourth probable proton-translocation channel is at the interface of subunits N, K, J and A. The structure indicates that proton translocation in complex I, uniquely, involves coordinated conformational changes in six symmetrical structural elements."}],"page":"414 - 421","year":"2011","day":"25","publication":"Nature","publication_status":"published","citation":{"short":"R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421.","ieee":"R. Efremov and L. A. Sazanov, “Structure of the membrane domain of respiratory complex i,” <i>Nature</i>, vol. 476, no. 7361. Nature Publishing Group, pp. 414–421, 2011.","apa":"Efremov, R., &#38; Sazanov, L. A. (2011). Structure of the membrane domain of respiratory complex i. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature10330\">https://doi.org/10.1038/nature10330</a>","ista":"Efremov R, Sazanov LA. 2011. Structure of the membrane domain of respiratory complex i. Nature. 476(7361), 414–421.","ama":"Efremov R, Sazanov LA. Structure of the membrane domain of respiratory complex i. <i>Nature</i>. 2011;476(7361):414-421. doi:<a href=\"https://doi.org/10.1038/nature10330\">10.1038/nature10330</a>","chicago":"Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” <i>Nature</i>. Nature Publishing Group, 2011. <a href=\"https://doi.org/10.1038/nature10330\">https://doi.org/10.1038/nature10330</a>.","mla":"Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” <i>Nature</i>, vol. 476, no. 7361, Nature Publishing Group, 2011, pp. 414–21, doi:<a href=\"https://doi.org/10.1038/nature10330\">10.1038/nature10330</a>."},"author":[{"first_name":"Rouslan","last_name":"Efremov","full_name":"Efremov, Rouslan G"},{"orcid":"0000-0002-0977-7989","first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","full_name":"Leonid Sazanov","last_name":"Sazanov"}]},{"status":"public","page":"532 - 540","abstract":[{"lang":"eng","text":"Complex I is the first enzyme of the respiratory chain and plays a central role in cellular energy production. It has been implicated in many human neurodegenerative diseases, as well as in ageing. One of the biggest membrane protein complexes, it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously, we have determined structures of the hydrophilic domain in several redox states. Last year was marked by fascinating breakthroughs in the understanding of the complete structure. We described the architecture of the membrane domain and of the entire bacterial complex I. X-ray analysis of the larger mitochondrial enzyme has also been published. The core subunits of the bacterial and mitochondrial enzymes have remarkably similar structures. The proposed mechanism of coupling between electron transfer and proton translocation involves long-range conformational changes, coordinated in part by a long α-helix, akin to the coupling rod of a steam engine."}],"year":"2011","day":"01","publication":"Current Opinion in Structural Biology","citation":{"short":"R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011) 532–540.","ieee":"R. Efremov and L. A. Sazanov, “Respiratory complex I: ‘steam engine’ of the cell?,” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4. Elsevier, pp. 532–540, 2011.","ista":"Efremov R, Sazanov LA. 2011. Respiratory complex I: ‘steam engine’ of the cell? Current Opinion in Structural Biology. 21(4), 532–540.","apa":"Efremov, R., &#38; Sazanov, L. A. (2011). Respiratory complex I: “steam engine” of the cell? <i>Current Opinion in Structural Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">https://doi.org/10.1016/j.sbi.2011.07.002</a>","chicago":"Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” <i>Current Opinion in Structural Biology</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">https://doi.org/10.1016/j.sbi.2011.07.002</a>.","ama":"Efremov R, Sazanov LA. Respiratory complex I: “steam engine” of the cell? <i>Current Opinion in Structural Biology</i>. 2011;21(4):532-540. doi:<a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">10.1016/j.sbi.2011.07.002</a>","mla":"Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4, Elsevier, 2011, pp. 532–40, doi:<a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">10.1016/j.sbi.2011.07.002</a>."},"publication_status":"published","author":[{"first_name":"Rouslan","last_name":"Efremov","full_name":"Efremov, Rouslan G"},{"full_name":"Leonid Sazanov","last_name":"Sazanov","orcid":"0000-0002-0977-7989","first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87"}],"month":"08","extern":1,"volume":21,"doi":"10.1016/j.sbi.2011.07.002","publist_id":"5111","intvolume":"        21","title":"Respiratory complex I: 'steam engine' of the cell?","issue":"4","date_updated":"2021-01-12T06:54:27Z","type":"journal_article","_id":"1974","acknowledgement":"The work in authors’ laboratory was funded by the Medical Research Council.","publisher":"Elsevier","date_created":"2018-12-11T11:54:59Z","date_published":"2011-08-01T00:00:00Z","quality_controlled":0},{"title":"Evolution of respiratory complex I &quot;Supernumerary&quot; subunits are present in the α-proteobacterial enzyme","intvolume":"       286","publist_id":"5112","doi":"10.1074/jbc.M110.194993","volume":286,"extern":1,"month":"02","quality_controlled":0,"date_published":"2011-02-18T00:00:00Z","acknowledgement":"This work was supported by the Medical Research Council. ","date_created":"2018-12-11T11:55:00Z","publisher":"American Society for Biochemistry and Molecular Biology","_id":"1975","type":"journal_article","issue":"7","date_updated":"2021-01-12T06:54:27Z","year":"2011","page":"5023 - 5033","abstract":[{"lang":"eng","text":"Modern α-proteobacteria are thought to be closely related to the ancient symbiont of eukaryotes, an ancestor of mitochondria. Respiratory complex I from α-proteobacteria and mitochondria is well conserved at the level of the 14 &quot;core&quot; subunits, consistent with that notion. Mitochondrial complex I contains the core subunits, present in all species, and up to 31 &quot;supernumerary&quot; subunits, generally thought to have originated only within eukaryotic lineages. However, the full protein composition of an α-proteobacterial complex I has not been established previously. Here, we report the first purification and characterization of complex I from the α-proteobacterium Paracoccus denitrificans. Single particle electron microscopy shows that the complex has a well defined L-shape. Unexpectedly, in addition to the 14 core subunits, the enzyme also contains homologues of three supernumerary mitochondrial subunits as follows: B17.2, AQDQ/18, and 13 kDa (bovine nomenclature). This finding suggests that evolution of complex I via addition of supernumerary or &quot;accessory&quot; subunits started before the original endosymbiotic event that led to the creation of the eukaryotic cell. It also provides further confirmation that α-proteobacteria are the closest extant relatives of mitochondria."}],"status":"public","author":[{"full_name":"Yip, Chui Y","last_name":"Yip","first_name":"Chui"},{"first_name":"Michael","last_name":"Harbour","full_name":"Harbour, Michael E"},{"last_name":"Jayawardena","full_name":"Jayawardena, Kamburapola G","first_name":"Kamburapola"},{"last_name":"Fearnley","full_name":"Fearnley, Ian M","first_name":"Ian"},{"full_name":"Leonid Sazanov","last_name":"Sazanov","orcid":"0000-0002-0977-7989","first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87"}],"publication_status":"published","citation":{"ista":"Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. 2011. Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. Journal of Biological Chemistry. 286(7), 5023–5033.","apa":"Yip, C., Harbour, M., Jayawardena, K., Fearnley, I., &#38; Sazanov, L. A. (2011). Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href=\"https://doi.org/10.1074/jbc.M110.194993\">https://doi.org/10.1074/jbc.M110.194993</a>","short":"C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, L.A. Sazanov, Journal of Biological Chemistry 286 (2011) 5023–5033.","ieee":"C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, and L. A. Sazanov, “Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme,” <i>Journal of Biological Chemistry</i>, vol. 286, no. 7. American Society for Biochemistry and Molecular Biology, pp. 5023–5033, 2011.","mla":"Yip, Chui, et al. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot; Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological Chemistry</i>, vol. 286, no. 7, American Society for Biochemistry and Molecular Biology, 2011, pp. 5023–33, doi:<a href=\"https://doi.org/10.1074/jbc.M110.194993\">10.1074/jbc.M110.194993</a>.","ama":"Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. <i>Journal of Biological Chemistry</i>. 2011;286(7):5023-5033. doi:<a href=\"https://doi.org/10.1074/jbc.M110.194993\">10.1074/jbc.M110.194993</a>","chicago":"Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and Leonid A Sazanov. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot; Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2011. <a href=\"https://doi.org/10.1074/jbc.M110.194993\">https://doi.org/10.1074/jbc.M110.194993</a>."},"day":"18","publication":"Journal of Biological Chemistry"},{"isi":1,"day":"23","status":"public","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097128/","open_access":"1"}],"abstract":[{"lang":"eng","text":"Spontaneous release of glutamate is important for maintaining synaptic strength and controlling spike timing in the brain. Mechanisms regulating spontaneous exocytosis remain poorly understood. Extracellular calcium concentration ([Ca2+]o) regulates Ca2+ entry through voltage-activated calcium channels (VACCs) and consequently is a pivotal determinant of action potential-evoked vesicle fusion. Extracellular Ca 2+ also enhances spontaneous release, but via unknown mechanisms. Here we report that external Ca2+ triggers spontaneous glutamate release more weakly than evoked release in mouse neocortical neurons. Blockade of VACCs has no effect on the spontaneous release rate or its dependence on [Ca2+]o. Intracellular [Ca2+] slowly increases in a minority of neurons following increases in [Ca2+]o. Furthermore, the enhancement of spontaneous release by extracellular calcium is insensitive to chelation of intracellular calcium by BAPTA. Activation of the calcium-sensing receptor (CaSR), a G-protein-coupled receptor present in nerve terminals, by several specific agonists increased spontaneous glutamate release. The frequency of spontaneous synaptic transmission was decreased in CaSR mutant neurons. The concentration-effect relationship for extracellular calcium regulation of spontaneous release was well described by a combination of CaSR-dependent and CaSR-independent mechanisms. Overall these results indicate that extracellular Ca2+ does not trigger spontaneous glutamate release by simply increasing calcium influx but stimulates CaSR and thereby promotes resting spontaneous glutamate release. "}],"publisher":"Wiley-Blackwell","date_created":"2018-12-11T11:46:39Z","scopus_import":"1","quality_controlled":"1","date_published":"2011-03-23T00:00:00Z","type":"journal_article","issue":"12","doi":"10.1523/JNEUROSCI.6398-10.2011","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"PeJo"}],"publist_id":"7353","author":[{"last_name":"Vyleta","full_name":"Vyleta, Nicholas","id":"36C4978E-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas"},{"full_name":"Smith, Stephen","last_name":"Smith","first_name":"Stephen"}],"language":[{"iso":"eng"}],"publication":"European Journal of Neuroscience","publication_status":"published","citation":{"ista":"Vyleta N, Smith S. 2011. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. European Journal of Neuroscience. 31(12), 4593–4606.","apa":"Vyleta, N., &#38; Smith, S. (2011). Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>","ieee":"N. Vyleta and S. Smith, “Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor,” <i>European Journal of Neuroscience</i>, vol. 31, no. 12. Wiley-Blackwell, pp. 4593–4606, 2011.","short":"N. Vyleta, S. Smith, European Journal of Neuroscience 31 (2011) 4593–4606.","mla":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>, vol. 31, no. 12, Wiley-Blackwell, 2011, pp. 4593–606, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>.","ama":"Vyleta N, Smith S. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. 2011;31(12):4593-4606. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>","chicago":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2011. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>."},"year":"2011","article_processing_charge":"No","oa_version":"Submitted Version","page":"4593 - 4606","date_updated":"2025-09-30T09:25:10Z","_id":"469","title":"Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor","intvolume":"        31","oa":1,"month":"03","volume":31,"external_id":{"isi":["000288750700025"]}}]