[{"doi":"10.1145/2073370.2073373","publication_status":"published","type":"conference","quality_controlled":0,"month":"12","extern":1,"publist_id":"4934","date_updated":"2021-01-12T06:55:19Z","year":"2011","author":[{"last_name":"Pfeil","full_name":"Pfeil, Jonas","first_name":"Jonas"},{"last_name":"Hildebrand","full_name":"Hildebrand, Kristian","first_name":"Kristian"},{"first_name":"Carsten","full_name":"Gremzow, Carsten","last_name":"Gremzow"},{"full_name":"Bernd Bickel","id":"49876194-F248-11E8-B48F-1D18A9856A87","last_name":"Bickel","orcid":"0000-0001-6511-9385","first_name":"Bernd"},{"full_name":"Alexa, Marc","last_name":"Alexa","first_name":"Marc"}],"title":"Throwable panoramic ball camera","fulldoi":"https://doi.org/10.1145/2073370.2073373","status":"public","citation":{"ieee":"J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, and M. Alexa, “Throwable panoramic ball camera,” presented at the SIGGRAPH Asia, 2011.","chicago":"Pfeil, Jonas, Kristian Hildebrand, Carsten Gremzow, Bernd Bickel, and Marc Alexa. “Throwable Panoramic Ball Camera.” ACM, 2011. <a href=\"https://doi.org/10.1145/2073370.2073373\">https://doi.org/10.1145/2073370.2073373</a>.","ista":"Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. 2011. Throwable panoramic ball camera. SIGGRAPH Asia.","ama":"Pfeil J, Hildebrand K, Gremzow C, Bickel B, Alexa M. Throwable panoramic ball camera. In: ACM; 2011. doi:<a href=\"https://doi.org/10.1145/2073370.2073373\">10.1145/2073370.2073373</a>","mla":"Pfeil, Jonas, et al. <i>Throwable Panoramic Ball Camera</i>. ACM, 2011, doi:<a href=\"https://doi.org/10.1145/2073370.2073373\">10.1145/2073370.2073373</a>.","apa":"Pfeil, J., Hildebrand, K., Gremzow, C., Bickel, B., &#38; Alexa, M. (2011). Throwable panoramic ball camera. Presented at the SIGGRAPH Asia, ACM. <a href=\"https://doi.org/10.1145/2073370.2073373\">https://doi.org/10.1145/2073370.2073373</a>","short":"J. Pfeil, K. Hildebrand, C. Gremzow, B. Bickel, M. Alexa, in:, ACM, 2011."},"date_created":"2018-12-11T11:55:43Z","abstract":[{"lang":"eng","text":"Acquiring panoramic images using stitching takes a lot of time and moving objects may cause ghosting. It is also difficult to obtain a full spherical panorama, because the downward picture cannot be captured while the camera is mounted on the tripod."}],"conference":{"name":"SIGGRAPH Asia"},"day":"01","publisher":"ACM","_id":"2100","date_published":"2011-12-01T00:00:00Z"},{"OA_type":"closed access","has_accepted_license":"1","issue":"12","month":"12","extern":"1","date_updated":"2026-02-23T08:59:44Z","oa_version":"None","year":"2011","author":[{"full_name":"Mandal, Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal","orcid":"0000-0001-5996-956X","first_name":"Pradeep K"},{"first_name":"S.","last_name":"Venkadesh","full_name":"Venkadesh, S."},{"first_name":"N.","full_name":"Gautham, N.","last_name":"Gautham"}],"intvolume":"        67","title":"Structure of d(CGGGTACCCG)4 as a four-way Holliday junction","status":"public","date_created":"2026-01-29T22:06:25Z","citation":{"chicago":"Mandal, Pradeep K, S. Venkadesh, and N. Gautham. “Structure of d(CGGGTACCCG)4 as a Four-Way Holliday Junction.” <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography, 2011. <a href=\"https://doi.org/10.1107/s1744309111046616\">https://doi.org/10.1107/s1744309111046616</a>.","ieee":"P. K. Mandal, S. Venkadesh, and N. Gautham, “Structure of d(CGGGTACCCG)4 as a four-way Holliday junction,” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 67, no. 12. International Union of Crystallography, pp. 1506–1510, 2011.","apa":"Mandal, P. K., Venkadesh, S., &#38; Gautham, N. (2011). Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. <i>Acta Crystallographica Section F Structural Biology Communications</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/s1744309111046616\">https://doi.org/10.1107/s1744309111046616</a>","short":"P.K. Mandal, S. Venkadesh, N. Gautham, Acta Crystallographica Section F Structural Biology Communications 67 (2011) 1506–1510.","ista":"Mandal PK, Venkadesh S, Gautham N. 2011. Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. Acta Crystallographica Section F Structural Biology Communications. 67(12), 1506–1510.","mla":"Mandal, Pradeep K., et al. “Structure of d(CGGGTACCCG)4 as a Four-Way Holliday Junction.” <i>Acta Crystallographica Section F Structural Biology Communications</i>, vol. 67, no. 12, International Union of Crystallography, 2011, pp. 1506–10, doi:<a href=\"https://doi.org/10.1107/s1744309111046616\">10.1107/s1744309111046616</a>.","ama":"Mandal PK, Venkadesh S, Gautham N. Structure of d(CGGGTACCCG)4 as a four-way Holliday junction. <i>Acta Crystallographica Section F Structural Biology Communications</i>. 2011;67(12):1506-1510. doi:<a href=\"https://doi.org/10.1107/s1744309111046616\">10.1107/s1744309111046616</a>"},"volume":67,"article_processing_charge":"No","publisher":"International Union of Crystallography","_id":"21107","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1107/s1744309111046616","publication_status":"published","type":"journal_article","quality_controlled":"1","language":[{"iso":"eng"}],"publication":"Acta Crystallographica Section F Structural Biology Communications","publication_identifier":{"issn":["1744-3091"]},"fulldoi":"https://doi.org/10.1107/s1744309111046616","abstract":[{"text":"The crystal structure of the decamer sequence d(CGGGTACCCG)4 as a four-way Holliday junction has been determined at 2.35 Å resolution. The sequence was designed in order to understand the principles that govern the relationship between sequence and branching structure. It crystallized as a four-way junction structure with an overall geometry similar to those of previously determined Holliday junction structures.","lang":"eng"}],"day":"01","page":"1506-1510","date_published":"2011-12-01T00:00:00Z"},{"publication_identifier":{"issn":["0006-291X"]},"fulldoi":"https://doi.org/10.1016/j.bbrc.2011.03.056","day":"15","abstract":[{"text":"We report here the crystal structure of the partially self-complementary decameric sequence d(CGGCGGCCGC), which self assembles to form a four-way junction with sticky ends. Each junction binds to four others through Watson–Crick base pairing at the sticky ends to form a rhombic structure. The rhombuses bind to each other and form two dimensional tiles. The tiles stack to form the crystal. The crystal diffracted in the space group P1 to a resolution of 2.5 Å. The junction has the anti-parallel stacked-X conformation like other junction structures, though the formation of the rhombic net noticeably alters the details of the junction geometry.","lang":"eng"}],"date_published":"2011-04-15T00:00:00Z","page":"548-551","doi":"10.1016/j.bbrc.2011.03.056","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","quality_controlled":"1","type":"journal_article","language":[{"iso":"eng"}],"publication":"Biochemical and Biophysical Research Communications","oa":1,"intvolume":"       407","title":"The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice","status":"public","pmid":1,"publisher":"Elsevier","date_created":"2026-01-29T22:09:20Z","article_processing_charge":"No","volume":407,"citation":{"chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">https://doi.org/10.1016/j.bbrc.2011.03.056</a>.","ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice,” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 3. Elsevier, pp. 548–551, 2011.","short":"S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research Communications 407 (2011) 548–551.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research Communications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">https://doi.org/10.1016/j.bbrc.2011.03.056</a>","ista":"Venkadesh S, Mandal PK, Gautham N. 2011. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. Biochemical and Biophysical Research Communications. 407(3), 548–551.","ama":"Venkadesh S, Mandal PK, Gautham N. The sequence d(CGGCGGCCGC) self-assembles into a two dimensional rhombic DNA lattice. <i>Biochemical and Biophysical Research Communications</i>. 2011;407(3):548-551. doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">10.1016/j.bbrc.2011.03.056</a>","mla":"Venkadesh, S., et al. “The Sequence d(CGGCGGCCGC) Self-Assembles into a Two Dimensional Rhombic DNA Lattice.” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 3, Elsevier, 2011, pp. 548–51, doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.056\">10.1016/j.bbrc.2011.03.056</a>."},"external_id":{"pmid":["21419105"]},"_id":"21108","article_type":"original","issue":"3","OA_type":"free access","has_accepted_license":"1","extern":"1","main_file_link":[{"url":"https://doi.org/10.1016/j.bbrc.2011.03.056","open_access":"1"}],"month":"04","date_updated":"2026-02-20T09:11:23Z","author":[{"last_name":"Venkadesh","full_name":"Venkadesh, S.","first_name":"S."},{"full_name":"Mandal, Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","last_name":"Mandal","orcid":"0000-0001-5996-956X","first_name":"Pradeep K"},{"full_name":"Gautham, N.","last_name":"Gautham","first_name":"N."}],"year":"2011","oa_version":"Published Version"},{"publication":"Biochemical and Biophysical Research Communications","language":[{"iso":"eng"}],"quality_controlled":"1","type":"journal_article","publication_status":"published","doi":"10.1016/j.bbrc.2011.03.007","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2011-04-08T00:00:00Z","page":"307-312","day":"08","abstract":[{"lang":"eng","text":"We report the 2.6 Å resolution crystal structure of the tetra-decamer d(CGCGGGTACCCGCG) in the tetragonal space group P43. This sequence contains the KpnI restriction site GGTACC in the centre which is flanked by alternating ‘CG’ sequences, and has a ‘TA’ step at the centre. These are features could favour the left-handed Z type helix. Despite this, overall the molecule has the A form. This is the first tetra-decamer crystallized in the A-DNA conformation, i.e. more than one full turn of the A helix. The crystallographic asymmetric unit consists of one tetra-decamer duplex. The helical twist and slide, as well as the base pair–base pair stacking interactions show alternations at the alternating pyrimidine–purine and purine–pyrimidine base steps. This variation is reminiscent of the dinucleotide repeat in left-handed Z-DNA helices. The crystal packing is unlike other A-DNA crystal structures, with each helix having a large number of contacts of many different types with symmetry-related neighbours."}],"fulldoi":"https://doi.org/10.1016/j.bbrc.2011.03.007","publication_identifier":{"issn":["0006-291X"]},"author":[{"first_name":"S.","last_name":"Venkadesh","full_name":"Venkadesh, S."},{"last_name":"Mandal","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","full_name":"Mandal, Pradeep K","orcid":"0000-0001-5996-956X","first_name":"Pradeep K"},{"full_name":"Gautham, N.","last_name":"Gautham","first_name":"N."}],"year":"2011","oa_version":"None","date_updated":"2026-02-20T09:01:51Z","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.bbrc.2011.03.007"}],"month":"04","issue":"2","has_accepted_license":"1","OA_type":"free access","external_id":{"pmid":["21397589"]},"article_type":"original","_id":"21109","publisher":"Elsevier","volume":407,"article_processing_charge":"No","date_created":"2026-01-29T22:10:30Z","citation":{"short":"S. Venkadesh, P.K. Mandal, N. Gautham, Biochemical and Biophysical Research Communications 407 (2011) 307–312.","apa":"Venkadesh, S., Mandal, P. K., &#38; Gautham, N. (2011). The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">https://doi.org/10.1016/j.bbrc.2011.03.007</a>","ama":"Venkadesh S, Mandal PK, Gautham N. The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. <i>Biochemical and Biophysical Research Communications</i>. 2011;407(2):307-312. doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">10.1016/j.bbrc.2011.03.007</a>","mla":"Venkadesh, S., et al. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2, Elsevier, 2011, pp. 307–12, doi:<a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">10.1016/j.bbrc.2011.03.007</a>.","ista":"Venkadesh S, Mandal PK, Gautham N. 2011. The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2. Biochemical and Biophysical Research Communications. 407(2), 307–312.","chicago":"Venkadesh, S., Pradeep K Mandal, and N. Gautham. “The Structure of a Full Turn of an A-DNA Duplex d(CGCGGGTACCCGCG)2.” <i>Biochemical and Biophysical Research Communications</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.bbrc.2011.03.007\">https://doi.org/10.1016/j.bbrc.2011.03.007</a>.","ieee":"S. Venkadesh, P. K. Mandal, and N. Gautham, “The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2,” <i>Biochemical and Biophysical Research Communications</i>, vol. 407, no. 2. Elsevier, pp. 307–312, 2011."},"status":"public","pmid":1,"intvolume":"       407","title":"The structure of a full turn of an A-DNA duplex d(CGCGGGTACCCGCG)2","oa":1},{"status":"public","fulldoi":"https://doi.org/10.1007/978-3-0348-0075-4_24","title":"Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators","intvolume":"        80","oa":1,"date_published":"2011-06-10T00:00:00Z","page":"463 - 477","_id":"2116","day":"10","publisher":"Birkhäuser","abstract":[{"lang":"eng","text":"Let P be the Ornstein-Uhlenbeck semigroup associated with the stochastic Cauchy problem  dU(t)=AU(t)dt+dWH(t), where A is the generator of a C 0-semigroup S on a Banach space E, H is a Hilbert subspace of E, and W H is an H-cylindrical Brownian motion. Assuming that S restricts to a C 0-semigroup on H, we obtain L p -bounds for D H P(t). We show that if P is analytic, then the invariance assumption is fulfilled. As an application we determine the L p -domain of the generator of P explicitly in the case where S restricts to a C 0-semigroup on H which is similar to an analytic contraction semigroup. The results are applied to the 1D stochastic heat equation driven by additive space-time white noise."}],"citation":{"chicago":"Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification for Analytic Ornstein-Uhlenbeck Operators.” In <i>Parabolic Problems</i>, 80:463–77. Birkhäuser, 2011. <a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">https://doi.org/10.1007/978-3-0348-0075-4_24</a>.","ieee":"J. Maas and J. Van Neerven, “Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators,” in <i>Parabolic Problems</i>, vol. 80, Birkhäuser, 2011, pp. 463–477.","apa":"Maas, J., &#38; Van Neerven, J. (2011). Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In <i>Parabolic Problems</i> (Vol. 80, pp. 463–477). Birkhäuser. <a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">https://doi.org/10.1007/978-3-0348-0075-4_24</a>","short":"J. Maas, J. Van Neerven, in:, Parabolic Problems, Birkhäuser, 2011, pp. 463–477.","ama":"Maas J, Van Neerven J. Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In: <i>Parabolic Problems</i>. Vol 80. Birkhäuser; 2011:463-477. doi:<a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">10.1007/978-3-0348-0075-4_24</a>","mla":"Maas, Jan, and Jan Van Neerven. “Gradient Estimates and Domain Identification for Analytic Ornstein-Uhlenbeck Operators.” <i>Parabolic Problems</i>, vol. 80, Birkhäuser, 2011, pp. 463–77, doi:<a href=\"https://doi.org/10.1007/978-3-0348-0075-4_24\">10.1007/978-3-0348-0075-4_24</a>.","ista":"Maas J, Van Neerven J. 2011.Gradient estimates and domain identification for analytic Ornstein-Uhlenbeck operators. In: Parabolic Problems. vol. 80, 463–477."},"date_created":"2018-12-11T11:55:48Z","volume":80,"extern":1,"type":"book_chapter","month":"06","quality_controlled":0,"main_file_link":[{"url":"http://arxiv.org/abs/0911.4336 ","open_access":"1"}],"publication_status":"published","doi":"10.1007/978-3-0348-0075-4_24","publication":"Parabolic Problems","author":[{"full_name":"Jan Maas","last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","orcid":"0000-0002-0845-1338"},{"last_name":"Van Neerven","full_name":"Van Neerven, Jan","first_name":"Jan"}],"acknowledgement":"The authors are supported by VIDI subsidy 639.032.201 (JM) and VICI subsidy 639.033.604 (JvN) of the Netherlands Organisation for Scientific Research (NWO). ","year":"2011","date_updated":"2021-01-12T06:55:24Z","publist_id":"4918"},{"oa":1,"intvolume":"        55","title":"Conical square functions and non-tangential maximal functions with respect to the Gaussian measure","fulldoi":"https://doi.org/10.5565/PUBLMAT_55211_03\t ","status":"public","volume":55,"citation":{"ista":"Maas J, Van Neerven J, Portal P. 2011. Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. Publicacions Matemàtiques. 55(2), 313–341.","ama":"Maas J, Van Neerven J, Portal P. Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. <i>Publicacions Matemàtiques</i>. 2011;55(2):313-341. doi:<a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">10.5565/PUBLMAT_55211_03  </a>","mla":"Maas, Jan, et al. “Conical Square Functions and Non-Tangential Maximal Functions with Respect to the Gaussian Measure.” <i>Publicacions Matemàtiques</i>, vol. 55, no. 2, Universitat Autònoma de Barcelona, Departament de Matemàtique, 2011, pp. 313–41, doi:<a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">10.5565/PUBLMAT_55211_03  </a>.","short":"J. Maas, J. Van Neerven, P. Portal, Publicacions Matemàtiques 55 (2011) 313–341.","apa":"Maas, J., Van Neerven, J., &#38; Portal, P. (2011). Conical square functions and non-tangential maximal functions with respect to the Gaussian measure. <i>Publicacions Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique. <a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">https://doi.org/10.5565/PUBLMAT_55211_03  </a>","ieee":"J. Maas, J. Van Neerven, and P. Portal, “Conical square functions and non-tangential maximal functions with respect to the Gaussian measure,” <i>Publicacions Matemàtiques</i>, vol. 55, no. 2. Universitat Autònoma de Barcelona, Departament de Matemàtique, pp. 313–341, 2011.","chicago":"Maas, Jan, Jan Van Neerven, and Pierre Portal. “Conical Square Functions and Non-Tangential Maximal Functions with Respect to the Gaussian Measure.” <i>Publicacions Matemàtiques</i>. Universitat Autònoma de Barcelona, Departament de Matemàtique, 2011. <a href=\"https://doi.org/10.5565/PUBLMAT_55211_03  \">https://doi.org/10.5565/PUBLMAT_55211_03  </a>."},"date_created":"2018-12-11T11:55:50Z","abstract":[{"lang":"eng","text":"We study, in L1(R̃n; γ) with respect to the gaussian measure, non- tangential maximal functions and conical square functions associ- ated with the Ornstein-Uhlenbeck operator by developing a set of techniques which allow us, to some extent, to compensate for the non-doubling character of the gaussian measure. The main result asserts that conical square functions can be controlled in L1-norm by non-tangential maximal functions. Along the way we prove a change of aperture result for the latter. This complements recent results on gaussian Hardy spaces due to Mauceri and Meda."}],"publisher":"Universitat Autònoma de Barcelona, Departament de Matemàtique","day":"01","_id":"2122","page":"313 - 341","date_published":"2011-07-01T00:00:00Z","issue":"2","doi":"10.5565/PUBLMAT_55211_03\t ","publication_status":"published","type":"journal_article","month":"07","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1003.4092"}],"quality_controlled":0,"extern":1,"publist_id":"4910","date_updated":"2021-01-12T06:55:26Z","year":"2011","author":[{"full_name":"Jan Maas","last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0845-1338","first_name":"Jan"},{"first_name":"Jan","full_name":"van Neerven, Jan M","last_name":"Van Neerven"},{"first_name":"Pierre","last_name":"Portal","full_name":"Portal, Pierre"}],"acknowledgement":"The first named author is supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO). The second named author is supported by VICI subsidy 639.033.604 of the Netherlands Organisation for Scientific Research (NWO","publication":"Publicacions Matemàtiques"},{"_id":"2123","publisher":"Birkhäuser","volume":11,"article_processing_charge":"No","date_created":"2018-12-11T11:55:51Z","citation":{"ista":"Clément P, Maas J. 2011. A Trotter product formula for gradient flows in metric spaces. Journal of Evolution Equations. 11(2), 405–427.","mla":"Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient Flows in Metric Spaces.” <i>Journal of Evolution Equations</i>, vol. 11, no. 2, Birkhäuser, 2011, pp. 405–27, doi:<a href=\"https://doi.org/10.1007/s00028-010-0096-5\">10.1007/s00028-010-0096-5</a>.","ama":"Clément P, Maas J. A Trotter product formula for gradient flows in metric spaces. <i>Journal of Evolution Equations</i>. 2011;11(2):405-427. doi:<a href=\"https://doi.org/10.1007/s00028-010-0096-5\">10.1007/s00028-010-0096-5</a>","apa":"Clément, P., &#38; Maas, J. (2011). A Trotter product formula for gradient flows in metric spaces. <i>Journal of Evolution Equations</i>. Birkhäuser. <a href=\"https://doi.org/10.1007/s00028-010-0096-5\">https://doi.org/10.1007/s00028-010-0096-5</a>","short":"P. Clément, J. Maas, Journal of Evolution Equations 11 (2011) 405–427.","ieee":"P. Clément and J. Maas, “A Trotter product formula for gradient flows in metric spaces,” <i>Journal of Evolution Equations</i>, vol. 11, no. 2. Birkhäuser, pp. 405–427, 2011.","chicago":"Clément, Philippe, and Jan Maas. “A Trotter Product Formula for Gradient Flows in Metric Spaces.” <i>Journal of Evolution Equations</i>. Birkhäuser, 2011. <a href=\"https://doi.org/10.1007/s00028-010-0096-5\">https://doi.org/10.1007/s00028-010-0096-5</a>."},"status":"public","oa":1,"title":"A Trotter product formula for gradient flows in metric spaces","intvolume":"        11","author":[{"full_name":"Clément, Philippe","last_name":"Clément","first_name":"Philippe"},{"orcid":"0000-0002-0845-1338","first_name":"Jan","full_name":"Maas, Jan","last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87"}],"acknowledgement":"The second named author is supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO).","oa_version":"None","year":"2011","publist_id":"4911","date_updated":"2021-11-16T08:05:46Z","extern":"1","month":"01","main_file_link":[{"url":"http://arxiv.org/abs/1005.0998","open_access":"1"}],"issue":"2","date_published":"2011-01-21T00:00:00Z","page":"405 - 427","day":"21","abstract":[{"text":"We prove a Trotter product formula for gradient flows in metric spaces. This result is applied to establish convergence in the L 2-Wasserstein metric of the splitting method for some Fokker-Planck equations and porous medium type equations perturbed by a potential.","lang":"eng"}],"fulldoi":"https://doi.org/10.1007/s00028-010-0096-5","publication":"Journal of Evolution Equations","language":[{"iso":"eng"}],"related_material":{"link":[{"url":"https://doi.org/10.1007/s00028-012-0173-z","relation":"erratum"}]},"publication_status":"published","type":"journal_article","doi":"10.1007/s00028-010-0096-5","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"publication":"Journal of Functional Analysis","acknowledgement":"Supported by Rubicon subsidy 680-50-0901 of the Netherlands Organisation for Scientific Research (NWO)","author":[{"first_name":"Jan","orcid":"0000-0002-0845-1338","last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Jan Maas"}],"year":"2011","date_updated":"2021-01-12T06:55:28Z","publist_id":"4909","extern":1,"quality_controlled":0,"type":"journal_article","month":"03","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1102.5238"}],"publication_status":"published","doi":"10.1016/j.jfa.2011.06.009 ","issue":"8","date_published":"2011-03-04T00:00:00Z","page":"2250 - 2292","_id":"2126","publisher":"Academic Press","day":"04","abstract":[{"text":"Let K be an irreducible and reversible Markov kernel on a finite set X. We construct a metric W on the set of probability measures on X and show that with respect to this metric, the law of the continuous time Markov chain evolves as the gradient flow of the entropy. This result is a discrete counterpart of the Wasserstein gradient flow interpretation of the heat flow in Rn by Jordan, Kinderlehrer and Otto (1998). The metric W is similar to, but different from, the L2-Wasserstein metric, and is defined via a discrete variant of the Benamou–Brenier formula.\n","lang":"eng"}],"date_created":"2018-12-11T11:55:51Z","citation":{"chicago":"Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal of Functional Analysis</i>. Academic Press, 2011. <a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">https://doi.org/10.1016/j.jfa.2011.06.009 </a>.","ieee":"J. Maas, “Gradient flows of the entropy for finite Markov chains,” <i>Journal of Functional Analysis</i>, vol. 261, no. 8. Academic Press, pp. 2250–2292, 2011.","short":"J. Maas, Journal of Functional Analysis 261 (2011) 2250–2292.","apa":"Maas, J. (2011). Gradient flows of the entropy for finite Markov chains. <i>Journal of Functional Analysis</i>. Academic Press. <a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">https://doi.org/10.1016/j.jfa.2011.06.009 </a>","mla":"Maas, Jan. “Gradient Flows of the Entropy for Finite Markov Chains.” <i>Journal of Functional Analysis</i>, vol. 261, no. 8, Academic Press, 2011, pp. 2250–92, doi:<a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">10.1016/j.jfa.2011.06.009 </a>.","ista":"Maas J. 2011. Gradient flows of the entropy for finite Markov chains. Journal of Functional Analysis. 261(8), 2250–2292.","ama":"Maas J. Gradient flows of the entropy for finite Markov chains. <i>Journal of Functional Analysis</i>. 2011;261(8):2250-2292. doi:<a href=\"https://doi.org/10.1016/j.jfa.2011.06.009 \">10.1016/j.jfa.2011.06.009 </a>"},"volume":261,"status":"public","fulldoi":"https://doi.org/10.1016/j.jfa.2011.06.009 ","title":"Gradient flows of the entropy for finite Markov chains","intvolume":"       261","oa":1},{"publication_status":"published","quality_controlled":0,"type":"preprint","month":"05","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1105.0761"}],"extern":1,"publist_id":"4886","date_updated":"2021-01-12T06:55:32Z","year":"2011","author":[{"first_name":"Ruzin","full_name":"Ağanoğlu, Ruzin","last_name":"Ağanoğlu"},{"first_name":"Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","full_name":"Mikhail Lemeshko"},{"first_name":"Břetislav","last_name":"Friedrich","full_name":"Friedrich, Břetislav"},{"first_name":"Rosario","full_name":"González-Férez, Rosario","last_name":"González Férez"},{"last_name":"Koch","full_name":"Koch, Christiane P","first_name":"Christiane"}],"acknowledgement":"Financial support from the Deutsche Forschungsgemeinschaft (Grant No. KO 2301/2), by the Spanish project FIS2008-02380 (MICINN) as well as the Grants FQM-2445 and FQM-4643 (Junta de Andaluc´ıa), Campus de Excelencia Internacional Proyecto GENIL CEB09-0010","publication":"Unknown","oa":1,"title":"Controlling a diatomic shape resonance with non-resonant light","status":"public","date_created":"2018-12-11T11:55:55Z","citation":{"ieee":"R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, and C. Koch, “Controlling a diatomic shape resonance with non-resonant light,” <i>Unknown</i>. ArXiv, 2011.","chicago":"Ağanoğlu, Ruzin, Mikhail Lemeshko, Břetislav Friedrich, Rosario González Férez, and Christiane Koch. “Controlling a Diatomic Shape Resonance with Non-Resonant Light.” <i>Unknown</i>. ArXiv, 2011.","mla":"Ağanoğlu, Ruzin, et al. “Controlling a Diatomic Shape Resonance with Non-Resonant Light.” <i>Unknown</i>, ArXiv, 2011.","ista":"Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. 2011. Controlling a diatomic shape resonance with non-resonant light. Unknown, .","ama":"Ağanoğlu R, Lemeshko M, Friedrich B, González Férez R, Koch C. Controlling a diatomic shape resonance with non-resonant light. <i>Unknown</i>. 2011.","short":"R. Ağanoğlu, M. Lemeshko, B. Friedrich, R. González Férez, C. Koch, Unknown (2011).","apa":"Ağanoğlu, R., Lemeshko, M., Friedrich, B., González Férez, R., &#38; Koch, C. (2011). Controlling a diatomic shape resonance with non-resonant light. <i>Unknown</i>. ArXiv."},"abstract":[{"text":"A (diatomic) shape resonance is a metastable state of a pair of colliding atoms quasi-bound by the centrifugal barrier imposed by the angular momentum involved in the collision. The temporary trapping of the atoms' scattering wavefunction corresponds to an enhanced atom pair density at low interatomic separations. This leads to larger overlap of the wavefunctions involved in a molecule formation process such as photoassociation, rendering the process more efficient. However, for an ensemble of atoms, the atom pair density will only be enhanced if the energy of the resonance comes close to the temperature of the atomic ensemble. Herein we explore the possibility of controlling the energy of a shape resonance by shifting it toward the temperature of atoms confined in a trap. The shifts are imparted by the interaction of non-resonant light with the anisotropic polarizability of the atom pair, which affects both the centrifugal barrier and the pair's rotational and vibrational levels. We find that at laser intensities of up to 5×109 W/cm2 the pair density is increased by one order of magnitude for 87Rb atoms at 100μK and by two orders of magnitude for 88Sr atoms at 20μK.","lang":"eng"}],"day":"04","publisher":"ArXiv","_id":"2138","date_published":"2011-05-04T00:00:00Z"},{"extern":1,"publication_status":"published","type":"journal_article","month":"05","quality_controlled":0,"main_file_link":[{"url":"http://arxiv.org/abs/1104.1046","open_access":"1"}],"issue":"5","doi":"10.1103/PhysRevA.83.051402","author":[{"full_name":"Mikhail Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","orcid":"0000-0002-6990-7802","first_name":"Mikhail"}],"publication":"Physical Review A - Atomic, Molecular, and Optical Physics","year":"2011","publist_id":"4775","date_updated":"2021-01-12T06:55:55Z","fulldoi":"https://doi.org/10.1103/PhysRevA.83.051402","status":"public","oa":1,"intvolume":"        83","title":"Shaping interactions between polar molecules with far-off-resonant light","date_published":"2011-05-27T00:00:00Z","_id":"2198","day":"27","publisher":"American Physical Society","volume":83,"date_created":"2018-12-11T11:56:17Z","citation":{"apa":"Lemeshko, M. (2011). Shaping interactions between polar molecules with far-off-resonant light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">https://doi.org/10.1103/PhysRevA.83.051402</a>","short":"M. Lemeshko, Physical Review A - Atomic, Molecular, and Optical Physics 83 (2011).","ista":"Lemeshko M. 2011. Shaping interactions between polar molecules with far-off-resonant light. Physical Review A - Atomic, Molecular, and Optical Physics. 83(5).","mla":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 83, no. 5, American Physical Society, 2011, doi:<a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">10.1103/PhysRevA.83.051402</a>.","ama":"Lemeshko M. Shaping interactions between polar molecules with far-off-resonant light. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. 2011;83(5). doi:<a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">10.1103/PhysRevA.83.051402</a>","chicago":"Lemeshko, Mikhail. “Shaping Interactions between Polar Molecules with Far-off-Resonant Light.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society, 2011. <a href=\"https://doi.org/10.1103/PhysRevA.83.051402\">https://doi.org/10.1103/PhysRevA.83.051402</a>.","ieee":"M. Lemeshko, “Shaping interactions between polar molecules with far-off-resonant light,” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 83, no. 5. American Physical Society, 2011."},"abstract":[{"lang":"eng","text":"We show that dressing polar molecules with a far-off-resonant optical field leads to new types of intermolecular potentials, which undergo a crossover from the inverse power to oscillating behavior depending on the intermolecular distance, and whose parameters can be tuned by varying the laser intensity and wavelength. We present analytic expressions for the potential energy surfaces, thereby providing direct access to the parameters of an optical field required to design intermolecular interactions experimentally."}]},{"publisher":"Proceedings of the National Academy of Sciences","article_processing_charge":"No","volume":108,"date_created":"2023-09-06T12:54:36Z","citation":{"ieee":"A. Bachmann, D. Wildemann, F. M. Praetorius, G. Fischer, and T. Kiefhaber, “Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction,” <i>PNAS</i>, vol. 108, no. 10. Proceedings of the National Academy of Sciences, pp. 3952–3957, 2011.","chicago":"Bachmann, Annett, Dirk Wildemann, Florian M Praetorius, Gunter Fischer, and Thomas Kiefhaber. “Mapping Backbone and Side-Chain Interactions in the Transition State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>. Proceedings of the National Academy of Sciences, 2011. <a href=\"https://doi.org/10.1073/pnas.1012668108\">https://doi.org/10.1073/pnas.1012668108</a>.","mla":"Bachmann, Annett, et al. “Mapping Backbone and Side-Chain Interactions in the Transition State of a Coupled Protein Folding and Binding Reaction.” <i>PNAS</i>, vol. 108, no. 10, Proceedings of the National Academy of Sciences, 2011, pp. 3952–57, doi:<a href=\"https://doi.org/10.1073/pnas.1012668108\">10.1073/pnas.1012668108</a>.","ama":"Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. <i>PNAS</i>. 2011;108(10):3952-3957. doi:<a href=\"https://doi.org/10.1073/pnas.1012668108\">10.1073/pnas.1012668108</a>","ista":"Bachmann A, Wildemann D, Praetorius FM, Fischer G, Kiefhaber T. 2011. Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. PNAS. 108(10), 3952–3957.","short":"A. Bachmann, D. Wildemann, F.M. Praetorius, G. Fischer, T. Kiefhaber, PNAS 108 (2011) 3952–3957.","apa":"Bachmann, A., Wildemann, D., Praetorius, F. M., Fischer, G., &#38; Kiefhaber, T. (2011). Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction. <i>PNAS</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1012668108\">https://doi.org/10.1073/pnas.1012668108</a>"},"external_id":{"pmid":["21325613"]},"article_type":"original","_id":"14305","title":"Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction","intvolume":"       108","oa":1,"status":"public","pmid":1,"date_updated":"2023-11-07T11:50:29Z","author":[{"last_name":"Bachmann","full_name":"Bachmann, Annett","first_name":"Annett"},{"last_name":"Wildemann","full_name":"Wildemann, Dirk","first_name":"Dirk"},{"full_name":"Praetorius, Florian M","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","last_name":"Praetorius","first_name":"Florian M"},{"last_name":"Fischer","full_name":"Fischer, Gunter","first_name":"Gunter"},{"full_name":"Kiefhaber, Thomas","last_name":"Kiefhaber","first_name":"Thomas"}],"oa_version":"Published Version","year":"2011","issue":"10","extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1073/pnas.1012668108"}],"month":"01","day":"12","abstract":[{"text":"Understanding the mechanism of protein folding requires a detailed knowledge of the structural properties of the barriers separating unfolded from native conformations. The S-peptide from ribonuclease S forms its α-helical structure only upon binding to the folded S-protein. We characterized the transition state for this binding-induced folding reaction at high resolution by determining the effect of site-specific backbone thioxylation and side-chain modifications on the kinetics and thermodynamics of the reaction, which allows us to monitor formation of backbone hydrogen bonds and side-chain interactions in the transition state. The experiments reveal that α-helical structure in the S-peptide is absent in the transition state of binding. Recognition between the unfolded S-peptide and the S-protein is mediated by loosely packed hydrophobic side-chain interactions in two well defined regions on the S-peptide. Close packing and helix formation occurs rapidly after binding. Introducing hydrophobic residues at positions outside the recognition region can drastically slow down association.","lang":"eng"}],"date_published":"2011-01-12T00:00:00Z","page":"3952-3957","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"keyword":["Multidisciplinary"],"fulldoi":"https://doi.org/10.1073/pnas.1012668108","language":[{"iso":"eng"}],"publication":"PNAS","doi":"10.1073/pnas.1012668108","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","quality_controlled":"1","publication_status":"published"},{"title":"Arithmetic harmonic analysis on character and quiver varieties","intvolume":"       160","oa":1,"status":"public","fulldoi":"https://doi.org/10.1215/00127094-1444258","abstract":[{"lang":"eng","text":"We propose a general conjecture for the mixed Hodge polynomial of the generic character varieties of representations of the fundamental group of a Riemann surface of genus g to GLn(C) with fixed generic semisimple conjugacy classes at k punctures. This conjecture generalizes the Cauchy identity for Macdonald polynomials and is a common generalization of two formulas that we prove in this paper. The first is a formula for the E-polynomial of these character varieties which we obtain using the character table of GLn(Fq). We use this formula to compute the Euler characteristic of character varieties. The second formula gives the Poincaré polynomial of certain associated quiver varieties which we obtain using the character table of gln(Fq). In the last main result we prove that the Poincaré polynomials of the quiver varieties equal certain multiplicities in the tensor product of irreducible characters of GLn(Fq). As a consequence we find a curious connection between Kac-Moody algebras associated with comet-shaped, and typically wild, quivers and the representation theory of GLn(Fq)."}],"volume":160,"citation":{"apa":"Hausel, T., Letellier, E., &#38; Rodríguez Villegas, F. (2011). Arithmetic harmonic analysis on character and quiver varieties. <i>Duke Mathematical Journal</i>. Duke University Press. <a href=\"https://doi.org/10.1215/00127094-1444258\">https://doi.org/10.1215/00127094-1444258</a>","short":"T. Hausel, E. Letellier, F. Rodríguez Villegas, Duke Mathematical Journal 160 (2011) 323–400.","ista":"Hausel T, Letellier E, Rodríguez Villegas F. 2011. Arithmetic harmonic analysis on character and quiver varieties. Duke Mathematical Journal. 160(2), 323–400.","ama":"Hausel T, Letellier E, Rodríguez Villegas F. Arithmetic harmonic analysis on character and quiver varieties. <i>Duke Mathematical Journal</i>. 2011;160(2):323-400. doi:<a href=\"https://doi.org/10.1215/00127094-1444258\">10.1215/00127094-1444258</a>","mla":"Hausel, Tamás, et al. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” <i>Duke Mathematical Journal</i>, vol. 160, no. 2, Duke University Press, 2011, pp. 323–400, doi:<a href=\"https://doi.org/10.1215/00127094-1444258\">10.1215/00127094-1444258</a>.","chicago":"Hausel, Tamás, Emmanuel Letellier, and Fernando Rodríguez Villegas. “Arithmetic Harmonic Analysis on Character and Quiver Varieties.” <i>Duke Mathematical Journal</i>. Duke University Press, 2011. <a href=\"https://doi.org/10.1215/00127094-1444258\">https://doi.org/10.1215/00127094-1444258</a>.","ieee":"T. Hausel, E. Letellier, and F. Rodríguez Villegas, “Arithmetic harmonic analysis on character and quiver varieties,” <i>Duke Mathematical Journal</i>, vol. 160, no. 2. Duke University Press, pp. 323–400, 2011."},"date_created":"2018-12-11T11:52:11Z","day":"01","publisher":"Duke University Press","page":"323 - 400","_id":"1467","date_published":"2011-01-01T00:00:00Z","doi":"10.1215/00127094-1444258","issue":"2","quality_controlled":0,"main_file_link":[{"url":"http://arxiv.org/abs/0810.2076","open_access":"1"}],"month":"01","type":"journal_article","publication_status":"published","extern":1,"date_updated":"2021-01-12T06:50:56Z","publist_id":"5728","year":"2011","publication":"Duke Mathematical Journal","acknowledgement":"Hausel’s work was supported by National Science Foundation grants DMS-0305505 and DMS-0604775, by an Alfred Sloan Fellowship, and by a Royal Society University Research Fellowship. Letellier’s work supported by Agence Nationale de la Recherche grant ANR-09-JCJC-0102-01.\nRodriguez-Villegas’s work supported by National Science Foundation grant DMS-0200605, by an FRA from the University of Texas at Austin, by EPSRC grant EP/G027110/1, by visiting fellowships at All Souls and Wadham Colleges in Oxford, and by a Research Scholarship from the Clay Mathematical Institute.","author":[{"last_name":"Hausel","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","full_name":"Tamas Hausel","first_name":"Tamas"},{"first_name":"Emmanuel","full_name":"Letellier, Emmanuel","last_name":"Letellier"},{"last_name":"Rodríguez Villegas","full_name":"Rodríguez Villegas, Fernando","first_name":"Fernando"}]},{"_id":"1863","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","page":"97 - 101","date_published":"2011-05-01T00:00:00Z","volume":79,"citation":{"chicago":"Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” <i>Theoretical Population Biology</i>. Academic Press, 2011. <a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">https://doi.org/10.1016/j.tpb.2010.12.002</a>.","ieee":"S. Novak, “The number of equilibria in the diallelic Levene model with multiple demes,” <i>Theoretical Population Biology</i>, vol. 79, no. 3. Academic Press, pp. 97–101, 2011.","short":"S. Novak, Theoretical Population Biology 79 (2011) 97–101.","apa":"Novak, S. (2011). The number of equilibria in the diallelic Levene model with multiple demes. <i>Theoretical Population Biology</i>. Academic Press. <a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">https://doi.org/10.1016/j.tpb.2010.12.002</a>","ista":"Novak S. 2011. The number of equilibria in the diallelic Levene model with multiple demes. Theoretical Population Biology. 79(3), 97–101.","ama":"Novak S. The number of equilibria in the diallelic Levene model with multiple demes. <i>Theoretical Population Biology</i>. 2011;79(3):97-101. doi:<a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">10.1016/j.tpb.2010.12.002</a>","mla":"Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with Multiple Demes.” <i>Theoretical Population Biology</i>, vol. 79, no. 3, Academic Press, 2011, pp. 97–101, doi:<a href=\"https://doi.org/10.1016/j.tpb.2010.12.002\">10.1016/j.tpb.2010.12.002</a>."},"date_created":"2018-12-11T11:54:25Z","abstract":[{"text":"The Levene model is the simplest mathematical model to describe the evolution of gene frequencies in spatially subdivided populations. It provides insight into how locally varying selection promotes a population’s genetic diversity. Despite its simplicity, interesting problems have remained unsolved even in the diallelic case. In this paper we answer an open problem by establishing that for two alleles at one locus and J demes, up to 2J−1 polymorphic equilibria may coexist. We first present a proof for the case of stable monomorphisms and then show that the result also holds for protected alleles. These findings allow us to prove that any odd number (up to 2J−1) of equilibria is possible, before we extend the proof to even numbers. We conclude with some numerical results and show that for J&gt;2, the proportion of parameter space affording this maximum is extremely small.","lang":"eng"}],"day":"01","publisher":"Academic Press","fulldoi":"https://doi.org/10.1016/j.tpb.2010.12.002","status":"public","intvolume":"        79","title":"The number of equilibria in the diallelic Levene model with multiple demes","year":"2011","author":[{"first_name":"Sebastian","full_name":"Sebastian Novak","id":"461468AE-F248-11E8-B48F-1D18A9856A87","last_name":"Novak"}],"acknowledgement":"FWF 21305","publication":"Theoretical Population Biology","publist_id":"5236","date_updated":"2021-01-12T06:53:42Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"publication_status":"published","month":"05","type":"journal_article","quality_controlled":0,"extern":1,"issue":"3","doi":"10.1016/j.tpb.2010.12.002"},{"quality_controlled":0,"month":"08","type":"journal_article","publication_status":"published","extern":1,"doi":"10.1038/nature10330","issue":"7361","year":"2011","publication":"Nature","author":[{"first_name":"Rouslan","full_name":"Efremov, Rouslan G","last_name":"Efremov"},{"first_name":"Leonid A","orcid":"0000-0002-0977-7989","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","last_name":"Sazanov","full_name":"Leonid Sazanov"}],"acknowledgement":"This work was funded by the Medical Research Council.","date_updated":"2021-01-12T06:54:26Z","publist_id":"5110","status":"public","fulldoi":"https://doi.org/10.1038/nature10330","title":"Structure of the membrane domain of respiratory complex i","intvolume":"       476","page":"414 - 421","_id":"1973","date_published":"2011-08-25T00:00:00Z","abstract":[{"lang":"eng","text":"Complex I is the first and largest enzyme of the respiratory chain, coupling electron transfer between NADH and ubiquinone to the translocation of four protons across the membrane. It has a central role in cellular energy production and has been implicated in many human neurodegenerative diseases. The L-shaped enzyme consists of hydrophilic and membrane domains. Previously, we determined the structure of the hydrophilic domain. Here we report the crystal structure of the Esherichia coli complex I membrane domain at 3.0 Ã. resolution. It includes six subunits, NuoL, NuoM, NuoN, NuoA, NuoJ and NuoK, with 55 transmembrane helices. The fold of the homologous antiporter-like subunits L, M and N is novel, with two inverted structural repeats of five transmembrane helices arranged, unusually, face-to-back. Each repeat includes a discontinuous transmembrane helix and forms half of a channel across the membrane. A network of conserved polar residues connects the two half-channels, completing the proton translocation pathway. Unexpectedly, lysines rather than carboxylate residues act as the main elements of the proton pump in these subunits. The fourth probable proton-translocation channel is at the interface of subunits N, K, J and A. The structure indicates that proton translocation in complex I, uniquely, involves coordinated conformational changes in six symmetrical structural elements."}],"volume":476,"citation":{"chicago":"Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” <i>Nature</i>. Nature Publishing Group, 2011. <a href=\"https://doi.org/10.1038/nature10330\">https://doi.org/10.1038/nature10330</a>.","ieee":"R. Efremov and L. A. Sazanov, “Structure of the membrane domain of respiratory complex i,” <i>Nature</i>, vol. 476, no. 7361. Nature Publishing Group, pp. 414–421, 2011.","short":"R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421.","apa":"Efremov, R., &#38; Sazanov, L. A. (2011). Structure of the membrane domain of respiratory complex i. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature10330\">https://doi.org/10.1038/nature10330</a>","mla":"Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” <i>Nature</i>, vol. 476, no. 7361, Nature Publishing Group, 2011, pp. 414–21, doi:<a href=\"https://doi.org/10.1038/nature10330\">10.1038/nature10330</a>.","ama":"Efremov R, Sazanov LA. Structure of the membrane domain of respiratory complex i. <i>Nature</i>. 2011;476(7361):414-421. doi:<a href=\"https://doi.org/10.1038/nature10330\">10.1038/nature10330</a>","ista":"Efremov R, Sazanov LA. 2011. Structure of the membrane domain of respiratory complex i. Nature. 476(7361), 414–421."},"date_created":"2018-12-11T11:54:59Z","day":"25","publisher":"Nature Publishing Group"},{"title":"Respiratory complex I: 'steam engine' of the cell?","intvolume":"        21","fulldoi":"https://doi.org/10.1016/j.sbi.2011.07.002","status":"public","day":"01","publisher":"Elsevier","citation":{"ieee":"R. Efremov and L. A. Sazanov, “Respiratory complex I: ‘steam engine’ of the cell?,” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4. Elsevier, pp. 532–540, 2011.","chicago":"Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” <i>Current Opinion in Structural Biology</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">https://doi.org/10.1016/j.sbi.2011.07.002</a>.","ista":"Efremov R, Sazanov LA. 2011. Respiratory complex I: ‘steam engine’ of the cell? Current Opinion in Structural Biology. 21(4), 532–540.","mla":"Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” <i>Current Opinion in Structural Biology</i>, vol. 21, no. 4, Elsevier, 2011, pp. 532–40, doi:<a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">10.1016/j.sbi.2011.07.002</a>.","ama":"Efremov R, Sazanov LA. Respiratory complex I: “steam engine” of the cell? <i>Current Opinion in Structural Biology</i>. 2011;21(4):532-540. doi:<a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">10.1016/j.sbi.2011.07.002</a>","apa":"Efremov, R., &#38; Sazanov, L. A. (2011). Respiratory complex I: “steam engine” of the cell? <i>Current Opinion in Structural Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.sbi.2011.07.002\">https://doi.org/10.1016/j.sbi.2011.07.002</a>","short":"R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011) 532–540."},"date_created":"2018-12-11T11:54:59Z","volume":21,"abstract":[{"text":"Complex I is the first enzyme of the respiratory chain and plays a central role in cellular energy production. It has been implicated in many human neurodegenerative diseases, as well as in ageing. One of the biggest membrane protein complexes, it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously, we have determined structures of the hydrophilic domain in several redox states. Last year was marked by fascinating breakthroughs in the understanding of the complete structure. We described the architecture of the membrane domain and of the entire bacterial complex I. X-ray analysis of the larger mitochondrial enzyme has also been published. The core subunits of the bacterial and mitochondrial enzymes have remarkably similar structures. The proposed mechanism of coupling between electron transfer and proton translocation involves long-range conformational changes, coordinated in part by a long α-helix, akin to the coupling rod of a steam engine.","lang":"eng"}],"date_published":"2011-08-01T00:00:00Z","_id":"1974","page":"532 - 540","issue":"4","doi":"10.1016/j.sbi.2011.07.002","extern":1,"publication_status":"published","quality_controlled":0,"type":"journal_article","month":"08","publist_id":"5111","date_updated":"2021-01-12T06:54:27Z","author":[{"last_name":"Efremov","full_name":"Efremov, Rouslan G","first_name":"Rouslan"},{"last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","full_name":"Leonid Sazanov","first_name":"Leonid A","orcid":"0000-0002-0977-7989"}],"acknowledgement":"The work in authors’ laboratory was funded by the Medical Research Council.","publication":"Current Opinion in Structural Biology","year":"2011"},{"acknowledgement":"This work was supported by the Medical Research Council. ","author":[{"last_name":"Yip","full_name":"Yip, Chui Y","first_name":"Chui"},{"last_name":"Harbour","full_name":"Harbour, Michael E","first_name":"Michael"},{"first_name":"Kamburapola","full_name":"Jayawardena, Kamburapola G","last_name":"Jayawardena"},{"first_name":"Ian","last_name":"Fearnley","full_name":"Fearnley, Ian M"},{"full_name":"Leonid Sazanov","last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A","orcid":"0000-0002-0977-7989"}],"publication":"Journal of Biological Chemistry","year":"2011","publist_id":"5112","date_updated":"2021-01-12T06:54:27Z","extern":1,"publication_status":"published","month":"02","type":"journal_article","quality_controlled":0,"issue":"7","doi":"10.1074/jbc.M110.194993","date_published":"2011-02-18T00:00:00Z","_id":"1975","page":"5023 - 5033","publisher":"American Society for Biochemistry and Molecular Biology","day":"18","date_created":"2018-12-11T11:55:00Z","citation":{"short":"C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, L.A. Sazanov, Journal of Biological Chemistry 286 (2011) 5023–5033.","apa":"Yip, C., Harbour, M., Jayawardena, K., Fearnley, I., &#38; Sazanov, L. A. (2011). Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href=\"https://doi.org/10.1074/jbc.M110.194993\">https://doi.org/10.1074/jbc.M110.194993</a>","mla":"Yip, Chui, et al. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot; Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological Chemistry</i>, vol. 286, no. 7, American Society for Biochemistry and Molecular Biology, 2011, pp. 5023–33, doi:<a href=\"https://doi.org/10.1074/jbc.M110.194993\">10.1074/jbc.M110.194993</a>.","ista":"Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. 2011. Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. Journal of Biological Chemistry. 286(7), 5023–5033.","ama":"Yip C, Harbour M, Jayawardena K, Fearnley I, Sazanov LA. Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme. <i>Journal of Biological Chemistry</i>. 2011;286(7):5023-5033. doi:<a href=\"https://doi.org/10.1074/jbc.M110.194993\">10.1074/jbc.M110.194993</a>","chicago":"Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and Leonid A Sazanov. “Evolution of Respiratory Complex I &#38;quot;Supernumerary&#38;quot; Subunits Are Present in the α-Proteobacterial Enzyme.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2011. <a href=\"https://doi.org/10.1074/jbc.M110.194993\">https://doi.org/10.1074/jbc.M110.194993</a>.","ieee":"C. Yip, M. Harbour, K. Jayawardena, I. Fearnley, and L. A. Sazanov, “Evolution of respiratory complex I &#38;quot;Supernumerary&#38;quot; subunits are present in the α-proteobacterial enzyme,” <i>Journal of Biological Chemistry</i>, vol. 286, no. 7. American Society for Biochemistry and Molecular Biology, pp. 5023–5033, 2011."},"volume":286,"abstract":[{"text":"Modern α-proteobacteria are thought to be closely related to the ancient symbiont of eukaryotes, an ancestor of mitochondria. Respiratory complex I from α-proteobacteria and mitochondria is well conserved at the level of the 14 &quot;core&quot; subunits, consistent with that notion. Mitochondrial complex I contains the core subunits, present in all species, and up to 31 &quot;supernumerary&quot; subunits, generally thought to have originated only within eukaryotic lineages. However, the full protein composition of an α-proteobacterial complex I has not been established previously. Here, we report the first purification and characterization of complex I from the α-proteobacterium Paracoccus denitrificans. Single particle electron microscopy shows that the complex has a well defined L-shape. Unexpectedly, in addition to the 14 core subunits, the enzyme also contains homologues of three supernumerary mitochondrial subunits as follows: B17.2, AQDQ/18, and 13 kDa (bovine nomenclature). This finding suggests that evolution of complex I via addition of supernumerary or &quot;accessory&quot; subunits started before the original endosymbiotic event that led to the creation of the eukaryotic cell. It also provides further confirmation that α-proteobacteria are the closest extant relatives of mitochondria.","lang":"eng"}],"fulldoi":"https://doi.org/10.1074/jbc.M110.194993","status":"public","title":"Evolution of respiratory complex I &quot;Supernumerary&quot; subunits are present in the α-proteobacterial enzyme","intvolume":"       286"},{"doi":"10.1523/JNEUROSCI.6398-10.2011","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","quality_controlled":"1","publication_status":"published","language":[{"iso":"eng"}],"publication":"European Journal of Neuroscience","fulldoi":"https://doi.org/10.1523/JNEUROSCI.6398-10.2011","day":"23","abstract":[{"lang":"eng","text":"Spontaneous release of glutamate is important for maintaining synaptic strength and controlling spike timing in the brain. Mechanisms regulating spontaneous exocytosis remain poorly understood. Extracellular calcium concentration ([Ca2+]o) regulates Ca2+ entry through voltage-activated calcium channels (VACCs) and consequently is a pivotal determinant of action potential-evoked vesicle fusion. Extracellular Ca 2+ also enhances spontaneous release, but via unknown mechanisms. Here we report that external Ca2+ triggers spontaneous glutamate release more weakly than evoked release in mouse neocortical neurons. Blockade of VACCs has no effect on the spontaneous release rate or its dependence on [Ca2+]o. Intracellular [Ca2+] slowly increases in a minority of neurons following increases in [Ca2+]o. Furthermore, the enhancement of spontaneous release by extracellular calcium is insensitive to chelation of intracellular calcium by BAPTA. Activation of the calcium-sensing receptor (CaSR), a G-protein-coupled receptor present in nerve terminals, by several specific agonists increased spontaneous glutamate release. The frequency of spontaneous synaptic transmission was decreased in CaSR mutant neurons. The concentration-effect relationship for extracellular calcium regulation of spontaneous release was well described by a combination of CaSR-dependent and CaSR-independent mechanisms. Overall these results indicate that extracellular Ca2+ does not trigger spontaneous glutamate release by simply increasing calcium influx but stimulates CaSR and thereby promotes resting spontaneous glutamate release. "}],"date_published":"2011-03-23T00:00:00Z","page":"4593 - 4606","issue":"12","department":[{"_id":"PeJo"}],"month":"03","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097128/","open_access":"1"}],"isi":1,"date_updated":"2025-09-30T09:25:10Z","publist_id":"7353","author":[{"first_name":"Nicholas","full_name":"Vyleta, Nicholas","last_name":"Vyleta","id":"36C4978E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Stephen","last_name":"Smith","full_name":"Smith, Stephen"}],"year":"2011","oa_version":"Submitted Version","intvolume":"        31","title":"Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor","oa":1,"status":"public","publisher":"Wiley-Blackwell","article_processing_charge":"No","volume":31,"citation":{"chicago":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2011. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>.","ieee":"N. Vyleta and S. Smith, “Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor,” <i>European Journal of Neuroscience</i>, vol. 31, no. 12. Wiley-Blackwell, pp. 4593–4606, 2011.","apa":"Vyleta, N., &#38; Smith, S. (2011). Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>","short":"N. Vyleta, S. Smith, European Journal of Neuroscience 31 (2011) 4593–4606.","mla":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>, vol. 31, no. 12, Wiley-Blackwell, 2011, pp. 4593–606, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>.","ama":"Vyleta N, Smith S. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. 2011;31(12):4593-4606. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>","ista":"Vyleta N, Smith S. 2011. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. European Journal of Neuroscience. 31(12), 4593–4606."},"date_created":"2018-12-11T11:46:39Z","external_id":{"isi":["000288750700025"]},"_id":"469"},{"volume":2011,"article_processing_charge":"No","date_created":"2018-12-11T11:46:45Z","citation":{"ieee":"A. Schlögl, C. Vidaurre, and T. Sander, “BioSig: The free and open source software library for biomedical signal processing,” <i>Computational Intelligence and Neuroscience</i>, vol. 2011. Hindawi Publishing Corporation, 2011.","chicago":"Schlögl, Alois, Carmen Vidaurre, and Tilmann Sander. “BioSig: The Free and Open Source Software Library for Biomedical Signal Processing.” <i>Computational Intelligence and Neuroscience</i>. Hindawi Publishing Corporation, 2011. <a href=\"https://doi.org/10.1155/2011/935364\">https://doi.org/10.1155/2011/935364</a>.","mla":"Schlögl, Alois, et al. “BioSig: The Free and Open Source Software Library for Biomedical Signal Processing.” <i>Computational Intelligence and Neuroscience</i>, vol. 2011, 935364, Hindawi Publishing Corporation, 2011, doi:<a href=\"https://doi.org/10.1155/2011/935364\">10.1155/2011/935364</a>.","ama":"Schlögl A, Vidaurre C, Sander T. BioSig: The free and open source software library for biomedical signal processing. <i>Computational Intelligence and Neuroscience</i>. 2011;2011. doi:<a href=\"https://doi.org/10.1155/2011/935364\">10.1155/2011/935364</a>","ista":"Schlögl A, Vidaurre C, Sander T. 2011. BioSig: The free and open source software library for biomedical signal processing. Computational Intelligence and Neuroscience. 2011, 935364.","apa":"Schlögl, A., Vidaurre, C., &#38; Sander, T. (2011). BioSig: The free and open source software library for biomedical signal processing. <i>Computational Intelligence and Neuroscience</i>. Hindawi Publishing Corporation. <a href=\"https://doi.org/10.1155/2011/935364\">https://doi.org/10.1155/2011/935364</a>","short":"A. Schlögl, C. Vidaurre, T. Sander, Computational Intelligence and Neuroscience 2011 (2011)."},"publisher":"Hindawi Publishing Corporation","_id":"490","external_id":{"isi":["000208906100033"]},"title":"BioSig: The free and open source software library for biomedical signal processing","intvolume":"      2011","oa":1,"file_date_updated":"2020-07-14T12:46:35Z","status":"public","date_updated":"2025-09-30T09:24:43Z","article_number":"935364","publist_id":"7330","ddc":["005"],"oa_version":"Published Version","year":"2011","author":[{"orcid":"0000-0002-5621-8100","first_name":"Alois","full_name":"Schlögl, Alois","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","last_name":"Schlögl"},{"first_name":"Carmen","full_name":"Vidaurre, Carmen","last_name":"Vidaurre"},{"first_name":"Tilmann","full_name":"Sander, Tilmann","last_name":"Sander"}],"has_accepted_license":"1","month":"01","isi":1,"pubrep_id":"947","department":[{"_id":"ScienComp"},{"_id":"PeJo"}],"abstract":[{"text":"BioSig is an open source software library for biomedical signal processing. The aim of the BioSig project is to foster research in biomedical signal processing by providing free and open source software tools for many different application areas. Some of the areas where BioSig can be employed are neuroinformatics, brain-computer interfaces, neurophysiology, psychology, cardiovascular systems, and sleep research. Moreover, the analysis of biosignals such as the electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), or respiration signals is a very relevant element of the BioSig project. Specifically, BioSig provides solutions for data acquisition, artifact processing, quality control, feature extraction, classification, modeling, and data visualization, to name a few. In this paper, we highlight several methods to help students and researchers to work more efficiently with biomedical signals. ","lang":"eng"}],"day":"01","license":"https://creativecommons.org/licenses/by/4.0/","date_published":"2011-01-01T00:00:00Z","file":[{"date_updated":"2020-07-14T12:46:35Z","date_created":"2018-12-12T10:07:44Z","access_level":"open_access","file_id":"4642","checksum":"8263bbf255171f2054f43f3db5f53b6e","file_size":2863551,"content_type":"application/pdf","file_name":"IST-2018-947-v1+1_2011_Schloegl_BioSig.pdf","relation":"main_file","creator":"system"}],"corr_author":"1","fulldoi":"https://doi.org/10.1155/2011/935364","language":[{"iso":"eng"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Computational Intelligence and Neuroscience","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","doi":"10.1155/2011/935364","scopus_import":"1","type":"journal_article","quality_controlled":"1","publication_status":"published"},{"fulldoi":"https://doi.org/10.1126/scisignal.2002617","corr_author":"1","date_published":"2011-11-08T00:00:00Z","day":"08","abstract":[{"lang":"eng","text":"In their search for antigens, lymphocytes continuously shuttle among blood vessels, lymph vessels, and lymphatic tissues. Chemokines mediate entry of lymphocytes into lymphatic tissues, and sphingosine 1-phosphate (S1P) promotes localization of lymphocytes to the vasculature. Both signals are sensed through G protein-coupled receptors (GPCRs). Most GPCRs undergo ligand-dependent homologous receptor desensitization, a process that decreases their signaling output after previous exposure to high ligand concentration. Such desensitization can explain why lymphocytes do not take an intermediate position between two signals but rather oscillate between them. The desensitization of S1P receptor 1 (S1PR1) is mediated by GPCR kinase 2 (GRK2). Deletion of GRK2 in lymphocytes compromises desensitization by high vascular S1P concentrations, thereby reducing responsiveness to the chemokine signal and trapping the cells in the vascular compartment. The desensitization kinetics of S1PR1 allows lymphocytes to dynamically shuttle between vasculature and lymphatic tissue, although the positional information in both compartments is static."}],"type":"journal_article","quality_controlled":"1","publication_status":"published","doi":"10.1126/scisignal.2002617","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Science Signaling","language":[{"iso":"eng"}],"status":"public","intvolume":"         4","title":"Setting the clock for recirculating lymphocytes","external_id":{"isi":["000296800500002"]},"_id":"491","publisher":"American Association for the Advancement of Science","article_processing_charge":"No","date_created":"2018-12-11T11:46:46Z","volume":4,"citation":{"mla":"Eichner, Alexander, and Michael K. Sixt. “Setting the Clock for Recirculating Lymphocytes.” <i>Science Signaling</i>, vol. 4, no. 198, pe43, American Association for the Advancement of Science, 2011, doi:<a href=\"https://doi.org/10.1126/scisignal.2002617\">10.1126/scisignal.2002617</a>.","ista":"Eichner A, Sixt MK. 2011. Setting the clock for recirculating lymphocytes. Science Signaling. 4(198), pe43.","ama":"Eichner A, Sixt MK. Setting the clock for recirculating lymphocytes. <i>Science Signaling</i>. 2011;4(198). doi:<a href=\"https://doi.org/10.1126/scisignal.2002617\">10.1126/scisignal.2002617</a>","apa":"Eichner, A., &#38; Sixt, M. K. (2011). Setting the clock for recirculating lymphocytes. <i>Science Signaling</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scisignal.2002617\">https://doi.org/10.1126/scisignal.2002617</a>","short":"A. Eichner, M.K. Sixt, Science Signaling 4 (2011).","ieee":"A. Eichner and M. K. Sixt, “Setting the clock for recirculating lymphocytes,” <i>Science Signaling</i>, vol. 4, no. 198. American Association for the Advancement of Science, 2011.","chicago":"Eichner, Alexander, and Michael K Sixt. “Setting the Clock for Recirculating Lymphocytes.” <i>Science Signaling</i>. American Association for the Advancement of Science, 2011. <a href=\"https://doi.org/10.1126/scisignal.2002617\">https://doi.org/10.1126/scisignal.2002617</a>."},"department":[{"_id":"MiSi"}],"month":"11","isi":1,"issue":"198","author":[{"last_name":"Eichner","id":"4DFA52AE-F248-11E8-B48F-1D18A9856A87","full_name":"Eichner, Alexander","first_name":"Alexander"},{"first_name":"Michael K","orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt"}],"year":"2011","oa_version":"None","date_updated":"2025-09-30T09:24:17Z","publist_id":"7329","article_number":"pe43"},{"article_processing_charge":"No","volume":30,"date_created":"2018-12-11T11:46:55Z","citation":{"ieee":"D. Schraivogel <i>et al.</i>, “CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells,” <i>EMBO Journal</i>, vol. 30, no. 20. Wiley-Blackwell, pp. 4309–4322, 2011.","chicago":"Schraivogel, Daniel, Lasse Weinmann, Dagmar Beier, Ghazaleh Tabatabai, Alexander Eichner, Jia Zhu, Martina Anton, et al. “CAMTA1 Is a Novel Tumour Suppressor Regulated by MiR-9/9 * in Glioblastoma Stem Cells.” <i>EMBO Journal</i>. Wiley-Blackwell, 2011. <a href=\"https://doi.org/10.1038/emboj.2011.301\">https://doi.org/10.1038/emboj.2011.301</a>.","mla":"Schraivogel, Daniel, et al. “CAMTA1 Is a Novel Tumour Suppressor Regulated by MiR-9/9 * in Glioblastoma Stem Cells.” <i>EMBO Journal</i>, vol. 30, no. 20, Wiley-Blackwell, 2011, pp. 4309–22, doi:<a href=\"https://doi.org/10.1038/emboj.2011.301\">10.1038/emboj.2011.301</a>.","ista":"Schraivogel D, Weinmann L, Beier D, Tabatabai G, Eichner A, Zhu J, Anton M, Sixt MK, Weller M, Beier C, Meister G. 2011. CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells. EMBO Journal. 30(20), 4309–4322.","ama":"Schraivogel D, Weinmann L, Beier D, et al. CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells. <i>EMBO Journal</i>. 2011;30(20):4309-4322. doi:<a href=\"https://doi.org/10.1038/emboj.2011.301\">10.1038/emboj.2011.301</a>","apa":"Schraivogel, D., Weinmann, L., Beier, D., Tabatabai, G., Eichner, A., Zhu, J., … Meister, G. (2011). CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells. <i>EMBO Journal</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1038/emboj.2011.301\">https://doi.org/10.1038/emboj.2011.301</a>","short":"D. Schraivogel, L. Weinmann, D. Beier, G. Tabatabai, A. Eichner, J. Zhu, M. Anton, M.K. Sixt, M. Weller, C. Beier, G. Meister, EMBO Journal 30 (2011) 4309–4322."},"publisher":"Wiley-Blackwell","_id":"518","article_type":"original","external_id":{"pmid":["21857646"],"isi":["000296715800018"]},"oa":1,"intvolume":"        30","title":"CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells","pmid":1,"status":"public","publist_id":"7301","date_updated":"2025-09-30T09:23:51Z","year":"2011","oa_version":"Submitted Version","author":[{"first_name":"Daniel","last_name":"Schraivogel","full_name":"Schraivogel, Daniel"},{"full_name":"Weinmann, Lasse","last_name":"Weinmann","first_name":"Lasse"},{"first_name":"Dagmar","last_name":"Beier","full_name":"Beier, Dagmar"},{"full_name":"Tabatabai, Ghazaleh","last_name":"Tabatabai","first_name":"Ghazaleh"},{"first_name":"Alexander","full_name":"Eichner, Alexander","id":"4DFA52AE-F248-11E8-B48F-1D18A9856A87","last_name":"Eichner"},{"first_name":"Jia","full_name":"Zhu, Jia","last_name":"Zhu"},{"last_name":"Anton","full_name":"Anton, Martina","first_name":"Martina"},{"orcid":"0000-0002-6620-9179","first_name":"Michael K","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt"},{"last_name":"Weller","full_name":"Weller, Michael","first_name":"Michael"},{"first_name":"Christoph","last_name":"Beier","full_name":"Beier, Christoph"},{"first_name":"Gunter","full_name":"Meister, Gunter","last_name":"Meister"}],"issue":"20","isi":1,"month":"10","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199389/"}],"department":[{"_id":"MiSi"}],"abstract":[{"text":"Cancer stem cells or cancer initiating cells are believed to contribute to cancer recurrence after therapy. MicroRNAs (miRNAs) are short RNA molecules with fundamental roles in gene regulation. The role of miRNAs in cancer stem cells is only poorly understood. Here, we report miRNA expression profiles of glioblastoma stem cell-containing CD133 + cell populations. We find that miR-9, miR-9 * (referred to as miR-9/9 *), miR-17 and miR-106b are highly abundant in CD133 + cells. Furthermore, inhibition of miR-9/9 * or miR-17 leads to reduced neurosphere formation and stimulates cell differentiation. Calmodulin-binding transcription activator 1 (CAMTA1) is a putative transcription factor, which induces the expression of the anti-proliferative cardiac hormone natriuretic peptide A (NPPA). We identify CAMTA1 as an miR-9/9 * and miR-17 target. CAMTA1 expression leads to reduced neurosphere formation and tumour growth in nude mice, suggesting that CAMTA1 can function as tumour suppressor. Consistently, CAMTA1 and NPPA expression correlate with patient survival. Our findings could provide a basis for novel strategies of glioblastoma therapy.","lang":"eng"}],"day":"19","page":"4309 - 4322","date_published":"2011-10-19T00:00:00Z","fulldoi":"https://doi.org/10.1038/emboj.2011.301","language":[{"iso":"eng"}],"publication":"EMBO Journal","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","doi":"10.1038/emboj.2011.301","publication_status":"published","quality_controlled":"1","type":"journal_article"}]