[{"language":[{"iso":"eng"}],"publication":"Developmental Biology","status":"public","page":"102 - 110","department":[{"_id":"CaHe"}],"volume":354,"date_published":"2011-06-01T00:00:00Z","pmid":1,"title":"Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail","intvolume":"       354","article_processing_charge":"No","publist_id":"3228","OA_type":"green","acknowledgement":"We thank David Grunwald for providing the spadetail-myc fusion construct. This work was supported by an NIH grant (GM079203) to D.K. and grants from the Austrian Academy of Sciences to P.S., and from the DFG, MPG and IST Austria to C.-P.H. R.R. was supported by a Developmental Biology Predoctoral Training Grant, T32HD007183, from the National Institute of Child Health and Human Development. B.L.M. was supported by an American Cancer Society fellowship (PF-07-048-01-DDC).","publication_status":"published","author":[{"last_name":"Row","full_name":"Row, Richard","first_name":"Richard"},{"id":"48F1E0D8-F248-11E8-B48F-1D18A9856A87","last_name":"Maître","orcid":"0000-0002-3688-1474","full_name":"Maître, Jean-Léon","first_name":"Jean-Léon"},{"full_name":"Martin, Benjamin","last_name":"Martin","first_name":"Benjamin"},{"last_name":"Stockinger","id":"261CB030-E90D-11E9-B182-F697D44B663C","full_name":"Stockinger, Petra","first_name":"Petra"},{"last_name":"Heisenberg","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J"},{"first_name":"David","last_name":"Kimelman","full_name":"Kimelman, David"}],"quality_controlled":"1","abstract":[{"lang":"eng","text":"The process of gastrulation is highly conserved across vertebrates on both the genetic and morphological levels, despite great variety in embryonic shape and speed of development. This mechanism spatially separates the germ layers and establishes the organizational foundation for future development. Mesodermal identity is specified in a superficial layer of cells, the epiblast, where cells maintain an epithelioid morphology. These cells involute to join the deeper hypoblast layer where they adopt a migratory, mesenchymal morphology. Expression of a cascade of related transcription factors orchestrates the parallel genetic transition from primitive to mature mesoderm. Although the early and late stages of this process are increasingly well understood, the transition between them has remained largely mysterious. We present here the first high resolution in vivo observations of the blebby transitional morphology of involuting mesodermal cells in a vertebrate embryo. We further demonstrate that the zebrafish spadetail mutation creates a reversible block in the maturation program, stalling cells in the transition state. This mutation creates an ideal system for dissecting the specific properties of cells undergoing the morphological transition of maturing mesoderm, as we demonstrate with a direct measurement of cell–cell adhesion."}],"day":"01","das_tickbox":"1","fulldoi":"https://doi.org/10.1016/j.ydbio.2011.03.025","issue":"1","doi":"10.1016/j.ydbio.2011.03.025","publisher":"Elsevier","OA_place":"repository","_id":"3379","date_updated":"2026-07-28T08:31:27Z","article_type":"original","isi":1,"oa":1,"citation":{"ista":"Row R, Maître J-L, Martin B, Stockinger P, Heisenberg C-PJ, Kimelman D. 2011. Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. Developmental Biology. 354(1), 102–110.","mla":"Row, Richard, et al. “Completion of the Epithelial to Mesenchymal Transition in Zebrafish Mesoderm Requires Spadetail.” <i>Developmental Biology</i>, vol. 354, no. 1, Elsevier, 2011, pp. 102–10, doi:<a href=\"https://doi.org/10.1016/j.ydbio.2011.03.025\">10.1016/j.ydbio.2011.03.025</a>.","apa":"Row, R., Maître, J.-L., Martin, B., Stockinger, P., Heisenberg, C.-P. J., &#38; Kimelman, D. (2011). Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. <i>Developmental Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ydbio.2011.03.025\">https://doi.org/10.1016/j.ydbio.2011.03.025</a>","ama":"Row R, Maître J-L, Martin B, Stockinger P, Heisenberg C-PJ, Kimelman D. Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. <i>Developmental Biology</i>. 2011;354(1):102-110. doi:<a href=\"https://doi.org/10.1016/j.ydbio.2011.03.025\">10.1016/j.ydbio.2011.03.025</a>","short":"R. Row, J.-L. Maître, B. Martin, P. Stockinger, C.-P.J. Heisenberg, D. Kimelman, Developmental Biology 354 (2011) 102–110.","chicago":"Row, Richard, Jean-Léon Maître, Benjamin Martin, Petra Stockinger, Carl-Philipp J Heisenberg, and David Kimelman. “Completion of the Epithelial to Mesenchymal Transition in Zebrafish Mesoderm Requires Spadetail.” <i>Developmental Biology</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.ydbio.2011.03.025\">https://doi.org/10.1016/j.ydbio.2011.03.025</a>.","ieee":"R. Row, J.-L. Maître, B. Martin, P. Stockinger, C.-P. J. Heisenberg, and D. Kimelman, “Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail,” <i>Developmental Biology</i>, vol. 354, no. 1. Elsevier, pp. 102–110, 2011."},"date_created":"2018-12-11T12:03:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","year":"2011","external_id":{"pmid":["21463614"],"isi":["000290550500010"]},"month":"06","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090540/","open_access":"1"}],"scopus_import":"1","oa_version":"Submitted Version"},{"month":"06","oa_version":"None","publication_identifier":{"eissn":["2064-8316"],"issn":["0001-6969"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","type":"journal_article","year":"2011","citation":{"chicago":"Fasy, Brittany Terese. “The Difference in Length of Curves in R^n.” <i>Acta Scientiarum Mathematicarum</i>. Springer Nature, 2011. <a href=\"https://doi.org/10.1007/BF03651375\">https://doi.org/10.1007/BF03651375</a>.","ieee":"B. T. Fasy, “The difference in length of curves in R^n,” <i>Acta Scientiarum Mathematicarum</i>, vol. 77, no. 1–2. Springer Nature, pp. 359–367, 2011.","ista":"Fasy BT. 2011. The difference in length of curves in R^n. Acta Scientiarum Mathematicarum. 77(1–2), 359–367.","mla":"Fasy, Brittany Terese. “The Difference in Length of Curves in R^n.” <i>Acta Scientiarum Mathematicarum</i>, vol. 77, no. 1–2, Springer Nature, 2011, pp. 359–67, doi:<a href=\"https://doi.org/10.1007/BF03651375\">10.1007/BF03651375</a>.","apa":"Fasy, B. T. (2011). The difference in length of curves in R^n. <i>Acta Scientiarum Mathematicarum</i>. Springer Nature. <a href=\"https://doi.org/10.1007/BF03651375\">https://doi.org/10.1007/BF03651375</a>","short":"B.T. Fasy, Acta Scientiarum Mathematicarum 77 (2011) 359–367.","ama":"Fasy BT. The difference in length of curves in R^n. <i>Acta Scientiarum Mathematicarum</i>. 2011;77(1-2):359-367. doi:<a href=\"https://doi.org/10.1007/BF03651375\">10.1007/BF03651375</a>"},"date_created":"2018-12-11T12:05:08Z","date_updated":"2026-07-28T08:11:07Z","article_type":"original","doi":"10.1007/BF03651375","publisher":"Springer Nature","_id":"3781","quality_controlled":"1","abstract":[{"text":"We bound the difference in length of two curves in terms of their total curvatures and the Fréchet distance. The bound is independent of the dimension of the ambient Euclidean space, it improves upon a bound by Cohen-Steiner and Edelsbrunner, and it generalizes a result by Fáry and Chakerian.","lang":"eng"}],"day":"01","das_tickbox":"1","fulldoi":"https://doi.org/10.1007/BF03651375","issue":"1-2","volume":77,"date_published":"2011-06-01T00:00:00Z","title":"The difference in length of curves in R^n","intvolume":"        77","publist_id":"2446","OA_type":"closed access","acknowledgement":"Funded by Graduate Aid in Areas of National Need (GAANN) Fellowship. The author would like to thank Herbert Edelsbrunner for his discussions and guidance.","article_processing_charge":"No","author":[{"first_name":"Brittany Terese","last_name":"Fasy","id":"F65D502E-E68D-11E9-9252-C644099818F6","full_name":"Fasy, Brittany Terese"}],"publication_status":"published","language":[{"iso":"eng"}],"publication":"Acta Scientiarum Mathematicarum","status":"public","page":"359 - 367","department":[{"_id":"HeEd"}]},{"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1111/j.1742-4658.2011.08136.x"}],"oa_version":"Published Version","month":"07","year":"2011","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"conference_abstract","corr_author":"1","date_created":"2018-12-11T12:03:01Z","citation":{"chicago":"Heisenberg, Carl-Philipp J. “Invited Lectures ‐ Symposia Area.” In <i>The FEBS Journal</i>, 278:24–24. Wiley, 2011. <a href=\"https://doi.org/10.1111/j.1742-4658.2011.08136.x\">https://doi.org/10.1111/j.1742-4658.2011.08136.x</a>.","ieee":"C.-P. J. Heisenberg, “Invited Lectures ‐ Symposia Area,” in <i>The FEBS Journal</i>, Torino, Italy, 2011, vol. 278, no. S1, pp. 24–24.","apa":"Heisenberg, C.-P. J. (2011). Invited Lectures ‐ Symposia Area. In <i>The FEBS Journal</i> (Vol. 278, pp. 24–24). Torino, Italy: Wiley. <a href=\"https://doi.org/10.1111/j.1742-4658.2011.08136.x\">https://doi.org/10.1111/j.1742-4658.2011.08136.x</a>","mla":"Heisenberg, Carl-Philipp J. “Invited Lectures ‐ Symposia Area.” <i>The FEBS Journal</i>, vol. 278, no. S1, Wiley, 2011, pp. 24–24, doi:<a href=\"https://doi.org/10.1111/j.1742-4658.2011.08136.x\">10.1111/j.1742-4658.2011.08136.x</a>.","ista":"Heisenberg C-PJ. 2011. Invited Lectures ‐ Symposia Area. The FEBS Journal. FEBS Congress on Biochemistry for Tomorrow’s Medicine vol. 278, 24–24.","short":"C.-P.J. Heisenberg, in:, The FEBS Journal, Wiley, 2011, pp. 24–24.","ama":"Heisenberg C-PJ. Invited Lectures ‐ Symposia Area. In: <i>The FEBS Journal</i>. Vol 278. Wiley; 2011:24-24. doi:<a href=\"https://doi.org/10.1111/j.1742-4658.2011.08136.x\">10.1111/j.1742-4658.2011.08136.x</a>"},"oa":1,"date_updated":"2026-07-28T08:27:55Z","_id":"3383","publisher":"Wiley","doi":"10.1111/j.1742-4658.2011.08136.x","OA_place":"publisher","fulldoi":"https://doi.org/10.1111/j.1742-4658.2011.08136.x","issue":"S1","conference":{"location":"Torino, Italy","start_date":"2011-06-25","name":"FEBS Congress on Biochemistry for Tomorrow's Medicine","end_date":"2011-06-30"},"quality_controlled":"1","day":"01","OA_type":"free access","publist_id":"3224","article_processing_charge":"No","intvolume":"       278","title":"Invited Lectures ‐ Symposia Area","publication_status":"published","author":[{"first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87"}],"date_published":"2011-07-01T00:00:00Z","volume":278,"status":"public","page":"24 - 24","publication":"The FEBS Journal","department":[{"_id":"CaHe"}],"language":[{"iso":"eng"}]},{"fulldoi":"https://doi.org/10.1073/pnas.1010767108","issue":"3","das_tickbox":"1","abstract":[{"lang":"eng","text":"Tissue surface tension (TST) is an important mechanical property influencing cell sorting and tissue envelopment. The study by Manning et al. (1) reported on a mathematical model describing TST on the basis of the balance between adhesive and tensile properties of the constituent cells. The model predicts that, in high-adhesion cell aggregates, surface cells will be stretched to maintain the same area of cell–cell contact as interior bulk cells, resulting in an elongated and flattened cell shape. The authors (1) observed flat and elongated cells at the surface of high-adhesion zebrafish germ-layer explants, which they argue are undifferentiated stretched germ-layer progenitor cells, and they use this observation as a validation of their model."}],"day":"18","quality_controlled":"1","_id":"3368","doi":"10.1073/pnas.1010767108","publisher":"National Academy of Sciences","department":[{"_id":"CaHe"}],"publication":"PNAS","page":"E9 - E10","status":"public","language":[{"iso":"eng"}],"author":[{"first_name":"Gabriel","full_name":"Krens, Gabriel","orcid":"0000-0003-4761-5996","last_name":"Krens","id":"2B819732-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Stephanie","last_name":"Möllmert","full_name":"Möllmert, Stephanie","id":"260FD49C-E911-11E9-B5EA-D9538404589B"},{"orcid":"0000-0002-0912-4566","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J"}],"publication_status":"published","title":"Enveloping cell layer differentiation at the surface of zebrafish germ layer tissue explants","intvolume":"       108","article_processing_charge":"No","publist_id":"3244","pmid":1,"volume":108,"date_published":"2011-01-18T00:00:00Z","year":"2011","corr_author":"1","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","oa_version":"Submitted Version","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024655","open_access":"1"}],"month":"01","external_id":{"isi":["000286310300003"],"pmid":["21212360"]},"isi":1,"article_type":"letter_note","date_updated":"2026-07-28T09:03:18Z","date_created":"2018-12-11T12:02:56Z","oa":1,"citation":{"ista":"Krens G, Möllmert S, Heisenberg C-PJ. 2011. Enveloping cell layer differentiation at the surface of zebrafish germ layer tissue explants. PNAS. 108(3), E9–E10.","apa":"Krens, G., Möllmert, S., &#38; Heisenberg, C.-P. J. (2011). Enveloping cell layer differentiation at the surface of zebrafish germ layer tissue explants. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1010767108\">https://doi.org/10.1073/pnas.1010767108</a>","mla":"Krens, Gabriel, et al. “Enveloping Cell Layer Differentiation at the Surface of Zebrafish Germ Layer Tissue Explants.” <i>PNAS</i>, vol. 108, no. 3, National Academy of Sciences, 2011, pp. E9–10, doi:<a href=\"https://doi.org/10.1073/pnas.1010767108\">10.1073/pnas.1010767108</a>.","ama":"Krens G, Möllmert S, Heisenberg C-PJ. Enveloping cell layer differentiation at the surface of zebrafish germ layer tissue explants. <i>PNAS</i>. 2011;108(3):E9-E10. doi:<a href=\"https://doi.org/10.1073/pnas.1010767108\">10.1073/pnas.1010767108</a>","short":"G. Krens, S. Möllmert, C.-P.J. Heisenberg, PNAS 108 (2011) E9–E10.","chicago":"Krens, Gabriel, Stephanie Möllmert, and Carl-Philipp J Heisenberg. “Enveloping Cell Layer Differentiation at the Surface of Zebrafish Germ Layer Tissue Explants.” <i>PNAS</i>. National Academy of Sciences, 2011. <a href=\"https://doi.org/10.1073/pnas.1010767108\">https://doi.org/10.1073/pnas.1010767108</a>.","ieee":"G. Krens, S. Möllmert, and C.-P. J. Heisenberg, “Enveloping cell layer differentiation at the surface of zebrafish germ layer tissue explants,” <i>PNAS</i>, vol. 108, no. 3. National Academy of Sciences, pp. E9–E10, 2011."}},{"publication":"Optics Letters","page":"1260 - 1262","status":"public","department":[{"_id":"CaHe"}],"related_material":{"record":[{"relation":"dissertation_contains","id":"1403","status":"public"}]},"language":[{"iso":"eng"}],"intvolume":"        36","title":"Measuring the complete force field of an optical trap","article_processing_charge":"No","publist_id":"3234","author":[{"full_name":"Jahnel, Marcus","last_name":"Jahnel","first_name":"Marcus"},{"first_name":"Martin","last_name":"Behrndt","id":"3ECECA3A-F248-11E8-B48F-1D18A9856A87","full_name":"Behrndt, Martin"},{"last_name":"Jannasch","full_name":"Jannasch, Anita","first_name":"Anita"},{"full_name":"Schaeffer, Erik","last_name":"Schaeffer","first_name":"Erik"},{"full_name":"Grill, Stephan","last_name":"Grill","first_name":"Stephan"}],"publication_status":"published","volume":36,"date_published":"2011-03-30T00:00:00Z","fulldoi":"https://doi.org/10.1364/OL.36.001260","issue":"7","quality_controlled":"1","abstract":[{"lang":"eng","text":"The use of optical traps to measure or apply forces on the molecular level requires a precise knowledge of the trapping force field. Close to the trap center, this field is typically approximated as linear in the displacement of the trapped microsphere. However, applications demanding high forces at low laser intensities can probe the light-microsphere interaction beyond the linear regime. Here, we measured the full nonlinear force and displacement response of an optical trap in two dimensions using a dual-beam optical trap setup with back-focal-plane photodetection. We observed a substantial stiffening of the trap beyond the linear regime that depends on microsphere size, in agreement with Mie theory calculations. Surprisingly, we found that the linear detection range for forces exceeds the one for displacement by far. Our approach allows for a complete calibration of an optical trap."}],"day":"30","_id":"3373","doi":"10.1364/OL.36.001260","publisher":"Optica Publishing Group","date_updated":"2026-07-29T10:07:18Z","isi":1,"ddc":["570"],"date_created":"2018-12-11T12:02:58Z","oa":1,"citation":{"apa":"Jahnel, M., Behrndt, M., Jannasch, A., Schaeffer, E., &#38; Grill, S. (2011). Measuring the complete force field of an optical trap. <i>Optics Letters</i>. Optica Publishing Group. <a href=\"https://doi.org/10.1364/OL.36.001260\">https://doi.org/10.1364/OL.36.001260</a>","mla":"Jahnel, Marcus, et al. “Measuring the Complete Force Field of an Optical Trap.” <i>Optics Letters</i>, vol. 36, no. 7, Optica Publishing Group, 2011, pp. 1260–62, doi:<a href=\"https://doi.org/10.1364/OL.36.001260\">10.1364/OL.36.001260</a>.","ista":"Jahnel M, Behrndt M, Jannasch A, Schaeffer E, Grill S. 2011. Measuring the complete force field of an optical trap. Optics Letters. 36(7), 1260–1262.","short":"M. Jahnel, M. Behrndt, A. Jannasch, E. Schaeffer, S. Grill, Optics Letters 36 (2011) 1260–1262.","ama":"Jahnel M, Behrndt M, Jannasch A, Schaeffer E, Grill S. Measuring the complete force field of an optical trap. <i>Optics Letters</i>. 2011;36(7):1260-1262. doi:<a href=\"https://doi.org/10.1364/OL.36.001260\">10.1364/OL.36.001260</a>","chicago":"Jahnel, Marcus, Martin Behrndt, Anita Jannasch, Erik Schaeffer, and Stephan Grill. “Measuring the Complete Force Field of an Optical Trap.” <i>Optics Letters</i>. Optica Publishing Group, 2011. <a href=\"https://doi.org/10.1364/OL.36.001260\">https://doi.org/10.1364/OL.36.001260</a>.","ieee":"M. Jahnel, M. Behrndt, A. Jannasch, E. Schaeffer, and S. Grill, “Measuring the complete force field of an optical trap,” <i>Optics Letters</i>, vol. 36, no. 7. Optica Publishing Group, pp. 1260–1262, 2011."},"year":"2011","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","main_file_link":[{"url":"https://www.osapublishing.org/ol/abstract.cfm?uri=ol-36-7-1260","open_access":"1"}],"scopus_import":"1","oa_version":"Published Version","external_id":{"isi":["000289251000080"]},"month":"03"},{"author":[{"first_name":"Nicholas H","orcid":"0000-0002-8548-5240","last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Michael","last_name":"Turelli","full_name":"Turelli, Michael"}],"publication_status":"published","article_processing_charge":"No","publist_id":"3214","title":"Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues of Allee effects","intvolume":"       178","date_published":"2011-09-01T00:00:00Z","volume":178,"department":[{"_id":"NiBa"}],"status":"public","page":"E48 - E75","publication":"American Naturalist","language":[{"iso":"eng"}],"_id":"3393","publisher":"University of Chicago Press","doi":"10.1086/661246","file_date_updated":"2020-07-14T12:46:11Z","fulldoi":"https://doi.org/10.1086/661246","has_accepted_license":"1","issue":"3","day":"01","abstract":[{"lang":"eng","text":"Unlike unconditionally advantageous “Fisherian” variants that tend to spread throughout a species range once introduced anywhere, “bistable” variants, such as chromosome translocations, have two alternative stable frequencies, absence and (near) fixation. Analogous to populations with Allee effects, bistable variants tend to increase locally only once they become sufficiently common, and their spread depends on their rate of increase averaged over all frequencies. Several proposed manipulations of insect populations, such as using Wolbachia or “engineered underdominance” to suppress vector-borne diseases, produce bistable rather than Fisherian dynamics. We synthesize and extend theoretical analyses concerning three features of their spatial behavior: rate of spread, conditions to initiate spread from a localized introduction, and wave stopping caused by variation in population densities or dispersal rates. Unlike Fisherian variants, bistable variants tend to spread spatially only for particular parameter combinations and initial conditions. Wave initiation requires introduction over an extended region, while subsequent spatial spread is slower than for Fisherian waves and can easily be halted by local spatial inhomogeneities. We present several new results, including robust sufficient conditions to initiate (and stop) spread, using a one-parameter cubic approximation applicable to several models. The results have both basic and applied implications."}],"quality_controlled":"1","file":[{"date_created":"2018-12-12T10:08:31Z","access_level":"open_access","file_size":629130,"content_type":"application/pdf","checksum":"7fd22a2ef3321a6fca6a439b3be5d8f4","creator":"system","file_id":"4692","date_updated":"2020-07-14T12:46:11Z","file_name":"IST-2016-554-v1+1_BartonTurelli2011_copy.pdf","relation":"main_file"}],"date_created":"2018-12-11T12:03:05Z","citation":{"mla":"Barton, Nicholas H., and Michael Turelli. “Spatial Waves of Advance with Bistable Dynamics: Cytoplasmic and Genetic Analogues of Allee Effects.” <i>American Naturalist</i>, vol. 178, no. 3, University of Chicago Press, 2011, pp. E48–75, doi:<a href=\"https://doi.org/10.1086/661246\">10.1086/661246</a>.","apa":"Barton, N. H., &#38; Turelli, M. (2011). Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues of Allee effects. <i>American Naturalist</i>. University of Chicago Press. <a href=\"https://doi.org/10.1086/661246\">https://doi.org/10.1086/661246</a>","ista":"Barton NH, Turelli M. 2011. Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues of Allee effects. American Naturalist. 178(3), E48–E75.","ama":"Barton NH, Turelli M. Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues of Allee effects. <i>American Naturalist</i>. 2011;178(3):E48-E75. doi:<a href=\"https://doi.org/10.1086/661246\">10.1086/661246</a>","short":"N.H. Barton, M. Turelli, American Naturalist 178 (2011) E48–E75.","chicago":"Barton, Nicholas H, and Michael Turelli. “Spatial Waves of Advance with Bistable Dynamics: Cytoplasmic and Genetic Analogues of Allee Effects.” <i>American Naturalist</i>. University of Chicago Press, 2011. <a href=\"https://doi.org/10.1086/661246\">https://doi.org/10.1086/661246</a>.","ieee":"N. H. Barton and M. Turelli, “Spatial waves of advance with bistable dynamics: Cytoplasmic and genetic analogues of Allee effects,” <i>American Naturalist</i>, vol. 178, no. 3. University of Chicago Press, pp. E48–E75, 2011."},"oa":1,"article_type":"original","isi":1,"date_updated":"2026-08-04T09:17:38Z","ddc":["570"],"oa_version":"Submitted Version","scopus_import":"1","pubrep_id":"554","month":"09","external_id":{"isi":["000294256800001"]},"year":"2011","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["0003-0147"],"eissn":["1537-5323"]}},{"intvolume":"        34","title":"Simulation of future climate scenarios with a weather generator","OA_type":"closed access","article_processing_charge":"No","author":[{"id":"cf8e546b-a9b0-11f0-a43b-aa89ed1b56d6","last_name":"Fatichi","full_name":"Fatichi, Simone","first_name":"Simone"},{"full_name":"Ivanov, Valeriy Y.","last_name":"Ivanov","first_name":"Valeriy Y."},{"first_name":"Enrica","full_name":"Caporali, Enrica","last_name":"Caporali"}],"publication_status":"published","volume":34,"date_published":"2011-04-01T00:00:00Z","publication":"Advances in Water Resources","page":"448-467","status":"public","language":[{"iso":"eng"}],"keyword":["Weather generator","Stochastic downscaling","Climate change","Hydro-meteorology","Rainfall model"],"_id":"22556","doi":"10.1016/j.advwatres.2010.12.013","publisher":"Elsevier","das_tickbox":"1","fulldoi":"https://doi.org/10.1016/j.advwatres.2010.12.013","issue":"4","quality_controlled":"1","abstract":[{"text":"Numerous studies across multiple disciplines search for insights on the effects of climate change at local spatial scales and at fine time resolutions. This study presents an overall methodology of using a weather generator for downscaling an ensemble of climate model outputs. The downscaled predictions can explicitly include climate model uncertainty, which offers valuable information for making probabilistic inferences about climate impacts. The hourly weather generator that serves as the downscaling tool is briefly presented. The generator is designed to reproduce a set of meteorological variables that can serve as input to hydrological, ecological, geomorphological, and agricultural models. The generator is capable of reproducing a wide set of climate statistics over a range of temporal scales, from extremes, to low-frequency interannual variability; its performance for many climate variables and their statistics over different aggregation periods is highly satisfactory. The use of the weather generator in simulations of future climate scenarios, as inferred from climate models, is described in detail. Using a previously developed methodology based on a Bayesian approach, the stochastic downscaling procedure derives the frequency distribution functions of factors of change for several climate statistics from a multi-model ensemble of outputs of General Circulation Models. The factors of change are subsequently applied to the statistics derived from observations to re-evaluate the parameters of the weather generator. Using embedded causal and statistical relationships, the generator simulates future realizations of climate for a specific point location at the hourly scale. Uncertainties present in the climate model realizations and the multi-model ensemble predictions are discussed. An application of the weather generator in reproducing present (1961–2000) and forecasting future (2081–2100) climate conditions is illustrated for the location of Tucson (AZ). The stochastic downscaling is carried out using simulations of eight General Circulation Models adopted in the IPCC 4AR, A1B emission scenario.","lang":"eng"}],"day":"01","date_created":"2026-07-27T12:30:24Z","citation":{"ieee":"S. Fatichi, V. Y. Ivanov, and E. Caporali, “Simulation of future climate scenarios with a weather generator,” <i>Advances in Water Resources</i>, vol. 34, no. 4. Elsevier, pp. 448–467, 2011.","chicago":"Fatichi, Simone, Valeriy Y. Ivanov, and Enrica Caporali. “Simulation of Future Climate Scenarios with a Weather Generator.” <i>Advances in Water Resources</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.advwatres.2010.12.013\">https://doi.org/10.1016/j.advwatres.2010.12.013</a>.","ama":"Fatichi S, Ivanov VY, Caporali E. Simulation of future climate scenarios with a weather generator. <i>Advances in Water Resources</i>. 2011;34(4):448-467. doi:<a href=\"https://doi.org/10.1016/j.advwatres.2010.12.013\">10.1016/j.advwatres.2010.12.013</a>","short":"S. Fatichi, V.Y. Ivanov, E. Caporali, Advances in Water Resources 34 (2011) 448–467.","apa":"Fatichi, S., Ivanov, V. Y., &#38; Caporali, E. (2011). Simulation of future climate scenarios with a weather generator. <i>Advances in Water Resources</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.advwatres.2010.12.013\">https://doi.org/10.1016/j.advwatres.2010.12.013</a>","mla":"Fatichi, Simone, et al. “Simulation of Future Climate Scenarios with a Weather Generator.” <i>Advances in Water Resources</i>, vol. 34, no. 4, Elsevier, 2011, pp. 448–67, doi:<a href=\"https://doi.org/10.1016/j.advwatres.2010.12.013\">10.1016/j.advwatres.2010.12.013</a>.","ista":"Fatichi S, Ivanov VY, Caporali E. 2011. Simulation of future climate scenarios with a weather generator. Advances in Water Resources. 34(4), 448–467."},"date_updated":"2026-08-06T10:13:12Z","article_type":"original","scopus_import":"1","oa_version":"None","month":"04","year":"2011","extern":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publication_identifier":{"issn":["0309-1708"]},"type":"journal_article"},{"status":"public","page":"720 - 739","publication":"Journal of the Royal Society Interface","department":[{"_id":"NiBa"}],"ec_funded":1,"language":[{"iso":"eng"}],"publist_id":"3232","article_processing_charge":"No","intvolume":"         8","title":"The statistical mechanics of a polygenic character under stabilizing selection mutation and drift","publication_status":"published","author":[{"full_name":"de Vladar, Harold","id":"2A181218-F248-11E8-B48F-1D18A9856A87","last_name":"de Vladar","orcid":"0000-0002-5985-7653","first_name":"Harold"},{"first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240"}],"date_published":"2011-05-01T00:00:00Z","pmid":1,"volume":8,"fulldoi":"https://doi.org/10.1098/rsif.2010.0438","issue":"58","quality_controlled":"1","day":"01","abstract":[{"text":"By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. This requires us to track only four macroscopic variables, instead of the distribution of all the allele frequencies that influence the trait. These macroscopic variables are the expectations of: the trait mean and its square, the genetic variance, and of a measure of heterozygosity, and are derived from a generating function that is in turn derived by maximizing an entropy measure. These four macroscopics are enough to accurately describe the dynamics of the trait mean and of its genetic variance (and in principle of any other quantity). Unlike previous approaches that were based on an infinite series of moments or cumulants, which had to be truncated arbitrarily, our calculations provide a well-defined approximation procedure. We apply the framework to abrupt and gradual changes in the optimum, as well as to changes in the strength of stabilizing selection. Our approximations are surprisingly accurate, even for systems with as few as five loci. We find that when the effects of drift are included, the expected genetic variance is hardly altered by directional selection, even though it fluctuates in any particular instance. We also find hysteresis, showing that even after averaging over the microscopic variables, the macroscopic trajectories retain a memory of the underlying genetic states.","lang":"eng"}],"_id":"3375","publisher":"Royal Society","doi":"10.1098/rsif.2010.0438","date_updated":"2026-08-12T14:07:44Z","article_type":"original","isi":1,"date_created":"2018-12-11T12:02:58Z","citation":{"chicago":"Vladar, Harold de, and Nicholas H Barton. “The Statistical Mechanics of a Polygenic Character under Stabilizing Selection Mutation and Drift.” <i>Journal of the Royal Society Interface</i>. Royal Society, 2011. <a href=\"https://doi.org/10.1098/rsif.2010.0438\">https://doi.org/10.1098/rsif.2010.0438</a>.","ieee":"H. de Vladar and N. H. Barton, “The statistical mechanics of a polygenic character under stabilizing selection mutation and drift,” <i>Journal of the Royal Society Interface</i>, vol. 8, no. 58. Royal Society, pp. 720–739, 2011.","mla":"de Vladar, Harold, and Nicholas H. Barton. “The Statistical Mechanics of a Polygenic Character under Stabilizing Selection Mutation and Drift.” <i>Journal of the Royal Society Interface</i>, vol. 8, no. 58, Royal Society, 2011, pp. 720–39, doi:<a href=\"https://doi.org/10.1098/rsif.2010.0438\">10.1098/rsif.2010.0438</a>.","apa":"de Vladar, H., &#38; Barton, N. H. (2011). The statistical mechanics of a polygenic character under stabilizing selection mutation and drift. <i>Journal of the Royal Society Interface</i>. Royal Society. <a href=\"https://doi.org/10.1098/rsif.2010.0438\">https://doi.org/10.1098/rsif.2010.0438</a>","ista":"de Vladar H, Barton NH. 2011. The statistical mechanics of a polygenic character under stabilizing selection mutation and drift. Journal of the Royal Society Interface. 8(58), 720–739.","ama":"de Vladar H, Barton NH. The statistical mechanics of a polygenic character under stabilizing selection mutation and drift. <i>Journal of the Royal Society Interface</i>. 2011;8(58):720-739. doi:<a href=\"https://doi.org/10.1098/rsif.2010.0438\">10.1098/rsif.2010.0438</a>","short":"H. de Vladar, N.H. Barton, Journal of the Royal Society Interface 8 (2011) 720–739."},"oa":1,"year":"2011","project":[{"_id":"25B07788-B435-11E9-9278-68D0E5697425","grant_number":"250152","name":"Limits to selection in biology and in evolutionary computation","call_identifier":"FP7"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","corr_author":"1","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061091/"}],"oa_version":"Submitted Version","scopus_import":"1","external_id":{"pmid":["21084341"],"isi":["000289671700011"]},"month":"05"},{"date_updated":"2025-09-30T09:51:13Z","isi":1,"citation":{"ista":"Blanc R, Henzinger TA, Hottelier T, Kovács L. 2010. ABC: Algebraic Bound Computation for loops. Logic for Programming, Artificial Intelligence, and Reasoning. LPAR: Logic for Programming, Artificial Intelligence and ReasoningLNCS vol. 6355, 103–118.","apa":"Blanc, R., Henzinger, T. A., Hottelier, T., &#38; Kovács, L. (2010). ABC: Algebraic Bound Computation for loops. In E. M. Clarke &#38; A. Voronkov (Eds.), <i>Logic for Programming, Artificial Intelligence, and Reasoning</i> (Vol. 6355, pp. 103–118). Berlin, Heidelberg: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-642-17511-4_7\">https://doi.org/10.1007/978-3-642-17511-4_7</a>","mla":"Blanc, Régis, et al. “ABC: Algebraic Bound Computation for Loops.” <i>Logic for Programming, Artificial Intelligence, and Reasoning</i>, edited by Edmund M Clarke and Andrei Voronkov, vol. 6355, Springer Nature, 2010, pp. 103–18, doi:<a href=\"https://doi.org/10.1007/978-3-642-17511-4_7\">10.1007/978-3-642-17511-4_7</a>.","ama":"Blanc R, Henzinger TA, Hottelier T, Kovács L. ABC: Algebraic Bound Computation for loops. In: Clarke EM, Voronkov A, eds. <i>Logic for Programming, Artificial Intelligence, and Reasoning</i>. Vol 6355. LNCS. Berlin, Heidelberg: Springer Nature; 2010:103-118. doi:<a href=\"https://doi.org/10.1007/978-3-642-17511-4_7\">10.1007/978-3-642-17511-4_7</a>","short":"R. Blanc, T.A. Henzinger, T. Hottelier, L. Kovács, in:, E.M. Clarke, A. Voronkov (Eds.), Logic for Programming, Artificial Intelligence, and Reasoning, Springer Nature, Berlin, Heidelberg, 2010, pp. 103–118.","chicago":"Blanc, Régis, Thomas A Henzinger, Thibaud Hottelier, and Laura Kovács. “ABC: Algebraic Bound Computation for Loops.” In <i>Logic for Programming, Artificial Intelligence, and Reasoning</i>, edited by Edmund M Clarke and Andrei Voronkov, 6355:103–18. LNCS. Berlin, Heidelberg: Springer Nature, 2010. <a href=\"https://doi.org/10.1007/978-3-642-17511-4_7\">https://doi.org/10.1007/978-3-642-17511-4_7</a>.","ieee":"R. Blanc, T. A. Henzinger, T. Hottelier, and L. Kovács, “ABC: Algebraic Bound Computation for loops,” in <i>Logic for Programming, Artificial Intelligence, and Reasoning</i>, Dakar, Senegal, 2010, vol. 6355, pp. 103–118."},"oa":1,"date_created":"2022-03-21T08:14:35Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"eisbn":["9783642175114"],"isbn":["9783642175107"],"issn":["0302-9743"],"eissn":["1611-3349"]},"type":"conference","corr_author":"1","series_title":"LNCS","year":"2010","external_id":{"isi":["000309668000007"]},"month":"05","main_file_link":[{"url":"https://infoscience.epfl.ch/record/186096","open_access":"1"}],"oa_version":"Submitted Version","scopus_import":"1","language":[{"iso":"eng"}],"page":"103-118","status":"public","publication":"Logic for Programming, Artificial Intelligence, and Reasoning","department":[{"_id":"ToHe"}],"editor":[{"last_name":"Clarke","full_name":"Clarke, Edmund M","first_name":"Edmund M"},{"first_name":"Andrei","last_name":"Voronkov","full_name":"Voronkov, Andrei"}],"date_published":"2010-05-01T00:00:00Z","volume":6355,"acknowledgement":"This work was supported in part by the Swiss NSF. The fourth author is supported by an FWF Hertha Firnberg Research grant (T425-N23).","article_processing_charge":"No","title":"ABC: Algebraic Bound Computation for loops","intvolume":"      6355","publication_status":"published","author":[{"first_name":"Régis","full_name":"Blanc, Régis","last_name":"Blanc"},{"first_name":"Thomas A","orcid":"0000-0002-2985-7724","full_name":"Henzinger, Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger"},{"first_name":"Thibaud","full_name":"Hottelier, Thibaud","last_name":"Hottelier"},{"last_name":"Kovács","full_name":"Kovács, Laura","first_name":"Laura"}],"quality_controlled":"1","day":"01","place":"Berlin, Heidelberg","abstract":[{"text":"We present ABC, a software tool for automatically computing symbolic upper bounds on the number of iterations of nested program loops. The system combines static analysis of programs with symbolic summation techniques to derive loop invariant relations between program variables. Iteration bounds are obtained from the inferred invariants, by replacing variables with bounds on their greatest values. We have successfully applied ABC to a large number of examples. The derived symbolic bounds express non-trivial polynomial relations over loop variables. We also report on results to automatically infer symbolic expressions over harmonic numbers as upper bounds on loop iteration counts.","lang":"eng"}],"fulldoi":"https://doi.org/10.1007/978-3-642-17511-4_7","conference":{"location":"Dakar, Senegal","name":"LPAR: Logic for Programming, Artificial Intelligence and Reasoning","start_date":"2010-04-25","end_date":"2010-05-01"},"publisher":"Springer Nature","doi":"10.1007/978-3-642-17511-4_7","_id":"10908"},{"fulldoi":"https://doi.org/10.1137/1.9781611973075.129","conference":{"location":"Austin, TX, United States","name":"SODA: Symposium on Discrete Algorithms","start_date":"2010-01-17","end_date":"2010-01-19"},"day":"01","abstract":[{"text":"We address the problem of localizing homology classes, namely, finding the cycle representing a given class with the most concise geometric measure. We focus on the volume measure, that is, the 1-norm of a cycle. Two main results are presented. First, we prove the problem is NP-hard to approximate within any constant factor. Second, we prove that for homology of dimension two or higher, the problem is NP-hard to approximate even when the Betti number is O(1). A side effect is the inapproximability of the problem of computing the nonbounding cycle with the smallest volume, and computing cycles representing a homology basis with the minimal total volume. We also discuss other geometric measures (diameter and radius) and show their disadvantages in homology localization. Our work is restricted to homology over the ℤ2 field.","lang":"eng"}],"quality_controlled":"1","_id":"10909","publisher":"Society for Industrial and Applied Mathematics","doi":"10.1137/1.9781611973075.129","department":[{"_id":"HeEd"}],"status":"public","page":"1594-1604","publication":"Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms","language":[{"iso":"eng"}],"related_material":{"record":[{"status":"public","relation":"later_version","id":"3267"}]},"author":[{"full_name":"Chen, Chao","last_name":"Chen","id":"3E92416E-F248-11E8-B48F-1D18A9856A87","first_name":"Chao"},{"first_name":"Daniel","last_name":"Freedman","full_name":"Freedman, Daniel"}],"publication_status":"published","acknowledgement":"Partially supported by the Austrian Science Fund under grantFSP-S9103-N04 and P20134-N13.","article_processing_charge":"No","title":"Hardness results for homology localization","date_published":"2010-02-01T00:00:00Z","year":"2010","corr_author":"1","type":"conference","publication_identifier":{"eisbn":["9781611973075"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","scopus_import":"1","month":"02","date_updated":"2025-09-30T09:22:32Z","date_created":"2022-03-21T08:24:07Z","citation":{"ista":"Chen C, Freedman D. 2010. Hardness results for homology localization. Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 1594–1604.","apa":"Chen, C., &#38; Freedman, D. (2010). Hardness results for homology localization. In <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (pp. 1594–1604). Austin, TX, United States: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611973075.129\">https://doi.org/10.1137/1.9781611973075.129</a>","mla":"Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.” <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Society for Industrial and Applied Mathematics, 2010, pp. 1594–604, doi:<a href=\"https://doi.org/10.1137/1.9781611973075.129\">10.1137/1.9781611973075.129</a>.","ama":"Chen C, Freedman D. Hardness results for homology localization. In: <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for Industrial and Applied Mathematics; 2010:1594-1604. doi:<a href=\"https://doi.org/10.1137/1.9781611973075.129\">10.1137/1.9781611973075.129</a>","short":"C. Chen, D. Freedman, in:, Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2010, pp. 1594–1604.","chicago":"Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.” In <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 1594–1604. Society for Industrial and Applied Mathematics, 2010. <a href=\"https://doi.org/10.1137/1.9781611973075.129\">https://doi.org/10.1137/1.9781611973075.129</a>.","ieee":"C. Chen and D. Freedman, “Hardness results for homology localization,” in <i>Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Austin, TX, United States, 2010, pp. 1594–1604."}},{"language":[{"iso":"eng"}],"publication":"Cold Spring Harbor Perspectives in Biology","status":"public","page":"a000539-a000539","volume":2,"date_published":"2010-02-03T00:00:00Z","pmid":1,"publication_status":"published","author":[{"last_name":"HETZER","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","first_name":"Martin W"}],"title":"The nuclear envelope","intvolume":"         2","article_processing_charge":"No","abstract":[{"lang":"eng","text":"The nuclear envelope (NE) is a highly regulated membrane barrier that separates the nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different proteins that have been implicated in chromatin organization and gene regulation. Although the nuclear membrane enables complex levels of gene expression, it also poses a challenge when it comes to cell division. To allow access of the mitotic spindle to chromatin, the nucleus of metazoans must completely disassemble during mitosis, generating the need to re-establish the nuclear compartment at the end of each cell division. Here, I summarize our current understanding of the dynamic remodeling of the NE during the cell cycle."}],"day":"03","quality_controlled":"1","issue":"3","fulldoi":"https://doi.org/10.1101/cshperspect.a000539","doi":"10.1101/cshperspect.a000539","publisher":"Cold Spring Harbor Laboratory","_id":"11097","keyword":["General Biochemistry","Genetics and Molecular Biology"],"article_type":"original","date_updated":"2024-10-14T11:26:41Z","citation":{"ama":"Hetzer M. The nuclear envelope. <i>Cold Spring Harbor Perspectives in Biology</i>. 2010;2(3):a000539-a000539. doi:<a href=\"https://doi.org/10.1101/cshperspect.a000539\">10.1101/cshperspect.a000539</a>","short":"M. Hetzer, Cold Spring Harbor Perspectives in Biology 2 (2010) a000539–a000539.","ista":"Hetzer M. 2010. The nuclear envelope. Cold Spring Harbor Perspectives in Biology. 2(3), a000539–a000539.","apa":"Hetzer, M. (2010). The nuclear envelope. <i>Cold Spring Harbor Perspectives in Biology</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/cshperspect.a000539\">https://doi.org/10.1101/cshperspect.a000539</a>","mla":"Hetzer, Martin. “The Nuclear Envelope.” <i>Cold Spring Harbor Perspectives in Biology</i>, vol. 2, no. 3, Cold Spring Harbor Laboratory, 2010, pp. a000539–a000539, doi:<a href=\"https://doi.org/10.1101/cshperspect.a000539\">10.1101/cshperspect.a000539</a>.","ieee":"M. Hetzer, “The nuclear envelope,” <i>Cold Spring Harbor Perspectives in Biology</i>, vol. 2, no. 3. Cold Spring Harbor Laboratory, pp. a000539–a000539, 2010.","chicago":"Hetzer, Martin. “The Nuclear Envelope.” <i>Cold Spring Harbor Perspectives in Biology</i>. Cold Spring Harbor Laboratory, 2010. <a href=\"https://doi.org/10.1101/cshperspect.a000539\">https://doi.org/10.1101/cshperspect.a000539</a>."},"date_created":"2022-04-07T07:52:49Z","type":"journal_article","publication_identifier":{"issn":["1943-0264"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","year":"2010","month":"02","external_id":{"pmid":["20300205"]},"scopus_import":"1","oa_version":"None"},{"language":[{"iso":"eng"}],"publication":"Aging","page":"74-75","status":"public","pmid":1,"volume":2,"date_published":"2010-02-01T00:00:00Z","author":[{"first_name":"Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","full_name":"HETZER, Martin W","last_name":"HETZER"}],"publication_status":"published","intvolume":"         2","title":"The role of the nuclear pore complex in aging of post-mitotic cells","article_processing_charge":"No","day":"01","quality_controlled":"1","fulldoi":"https://doi.org/10.18632/aging.100125","issue":"2","doi":"10.18632/aging.100125","publisher":"Impact Journals","_id":"11098","keyword":["Cell Biology","Aging"],"article_type":"original","date_updated":"2024-10-14T11:26:51Z","oa":1,"citation":{"ieee":"M. Hetzer, “The role of the nuclear pore complex in aging of post-mitotic cells,” <i>Aging</i>, vol. 2, no. 2. Impact Journals, pp. 74–75, 2010.","chicago":"Hetzer, Martin. “The Role of the Nuclear Pore Complex in Aging of Post-Mitotic Cells.” <i>Aging</i>. Impact Journals, 2010. <a href=\"https://doi.org/10.18632/aging.100125\">https://doi.org/10.18632/aging.100125</a>.","short":"M. Hetzer, Aging 2 (2010) 74–75.","ama":"Hetzer M. The role of the nuclear pore complex in aging of post-mitotic cells. <i>Aging</i>. 2010;2(2):74-75. doi:<a href=\"https://doi.org/10.18632/aging.100125\">10.18632/aging.100125</a>","apa":"Hetzer, M. (2010). The role of the nuclear pore complex in aging of post-mitotic cells. <i>Aging</i>. Impact Journals. <a href=\"https://doi.org/10.18632/aging.100125\">https://doi.org/10.18632/aging.100125</a>","mla":"Hetzer, Martin. “The Role of the Nuclear Pore Complex in Aging of Post-Mitotic Cells.” <i>Aging</i>, vol. 2, no. 2, Impact Journals, 2010, pp. 74–75, doi:<a href=\"https://doi.org/10.18632/aging.100125\">10.18632/aging.100125</a>.","ista":"Hetzer M. 2010. The role of the nuclear pore complex in aging of post-mitotic cells. Aging. 2(2), 74–75."},"date_created":"2022-04-07T07:52:58Z","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1945-4589"]},"extern":"1","year":"2010","month":"02","external_id":{"pmid":["20354266"]},"scopus_import":"1","oa_version":"Published Version","main_file_link":[{"open_access":"1","url":"https://doi.org/10.18632/aging.100125"}]},{"external_id":{"pmid":["20721671"]},"month":"10","oa_version":"None","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["0009-5915"],"eissn":["1432-0886"]},"type":"journal_article","year":"2010","extern":"1","citation":{"chicago":"Doucet, Christine M., and Martin Hetzer. “Nuclear Pore Biogenesis into an Intact Nuclear Envelope.” <i>Chromosoma</i>. Springer Nature, 2010. <a href=\"https://doi.org/10.1007/s00412-010-0289-2\">https://doi.org/10.1007/s00412-010-0289-2</a>.","ieee":"C. M. Doucet and M. Hetzer, “Nuclear pore biogenesis into an intact nuclear envelope,” <i>Chromosoma</i>, vol. 119. Springer Nature, pp. 469–477, 2010.","ista":"Doucet CM, Hetzer M. 2010. Nuclear pore biogenesis into an intact nuclear envelope. Chromosoma. 119, 469–477.","mla":"Doucet, Christine M., and Martin Hetzer. “Nuclear Pore Biogenesis into an Intact Nuclear Envelope.” <i>Chromosoma</i>, vol. 119, Springer Nature, 2010, pp. 469–77, doi:<a href=\"https://doi.org/10.1007/s00412-010-0289-2\">10.1007/s00412-010-0289-2</a>.","apa":"Doucet, C. M., &#38; Hetzer, M. (2010). Nuclear pore biogenesis into an intact nuclear envelope. <i>Chromosoma</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00412-010-0289-2\">https://doi.org/10.1007/s00412-010-0289-2</a>","short":"C.M. Doucet, M. Hetzer, Chromosoma 119 (2010) 469–477.","ama":"Doucet CM, Hetzer M. Nuclear pore biogenesis into an intact nuclear envelope. <i>Chromosoma</i>. 2010;119:469-477. doi:<a href=\"https://doi.org/10.1007/s00412-010-0289-2\">10.1007/s00412-010-0289-2</a>"},"date_created":"2022-04-07T07:53:12Z","date_updated":"2024-10-14T11:27:07Z","article_type":"review","publisher":"Springer Nature","doi":"10.1007/s00412-010-0289-2","keyword":["Genetics (clinical)","Genetics"],"_id":"11099","quality_controlled":"1","day":"01","abstract":[{"text":"Nuclear pore complexes (NPCs) serve as transport channels across the nuclear membrane, a double lipid bilayer that physically separates the nucleoplasm and cytoplasm of eukaryotic cells. New evidence suggests that the multiprotein nuclear pores also play a role in chromatin organization and gene expression. Given the importance of NPC function, it is not surprising that a growing list of human diseases and developmental defects have been linked to its malfunction. In order to fully understand the functional repertoire of NPCs and their essential role for nuclear organization, it is critical to determine the sequence of events that lead to the formation of nuclear pores. This is particularly relevant since NPC number, and possibly composition, are tightly linked to metabolic activity. Most of our knowledge is derived from NPC formation that occurs in dividing cells at the end of mitosis when the nuclear envelope (NE) and NPCs reform from disassembled precursors. However, NPC assembly also takes place during interphase into an intact NE. Importantly, this process is not restricted to dividing cells but also occurs during cell differentiation. Here, we will review aspects unique to this process, namely the regulation of nuclear expansion and the mechanisms of fusion between the outer and inner nuclear membranes. We will then discuss conserved and diverging mechanisms between post-mitotic and interphase assembly of the proteinaceous structure in light of recently published data.","lang":"eng"}],"fulldoi":"https://doi.org/10.1007/s00412-010-0289-2","date_published":"2010-10-01T00:00:00Z","volume":119,"pmid":1,"article_processing_charge":"No","intvolume":"       119","title":"Nuclear pore biogenesis into an intact nuclear envelope","author":[{"first_name":"Christine M.","last_name":"Doucet","full_name":"Doucet, Christine M."},{"last_name":"HETZER","full_name":"HETZER, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","first_name":"Martin W"}],"publication_status":"published","language":[{"iso":"eng"}],"page":"469-477","status":"public","publication":"Chromosoma"},{"extern":"1","year":"2010","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["0092-8674"]},"scopus_import":"1","oa_version":"Published Version","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.cell.2010.04.036"}],"month":"06","external_id":{"pmid":["20550937"]},"article_type":"original","date_updated":"2024-10-14T11:28:00Z","date_created":"2022-04-07T07:53:29Z","oa":1,"citation":{"ama":"Doucet CM, Talamas JA, Hetzer M. Cell cycle-dependent differences in nuclear pore complex assembly in metazoa. <i>Cell</i>. 2010;141(6):1030-1041. doi:<a href=\"https://doi.org/10.1016/j.cell.2010.04.036\">10.1016/j.cell.2010.04.036</a>","short":"C.M. Doucet, J.A. Talamas, M. Hetzer, Cell 141 (2010) 1030–1041.","mla":"Doucet, Christine M., et al. “Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa.” <i>Cell</i>, vol. 141, no. 6, Elsevier, 2010, pp. 1030–41, doi:<a href=\"https://doi.org/10.1016/j.cell.2010.04.036\">10.1016/j.cell.2010.04.036</a>.","apa":"Doucet, C. M., Talamas, J. A., &#38; Hetzer, M. (2010). Cell cycle-dependent differences in nuclear pore complex assembly in metazoa. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2010.04.036\">https://doi.org/10.1016/j.cell.2010.04.036</a>","ista":"Doucet CM, Talamas JA, Hetzer M. 2010. Cell cycle-dependent differences in nuclear pore complex assembly in metazoa. Cell. 141(6), 1030–1041.","ieee":"C. M. Doucet, J. A. Talamas, and M. Hetzer, “Cell cycle-dependent differences in nuclear pore complex assembly in metazoa,” <i>Cell</i>, vol. 141, no. 6. Elsevier, pp. 1030–1041, 2010.","chicago":"Doucet, Christine M., Jessica A. Talamas, and Martin Hetzer. “Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa.” <i>Cell</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.cell.2010.04.036\">https://doi.org/10.1016/j.cell.2010.04.036</a>."},"issue":"6","fulldoi":"https://doi.org/10.1016/j.cell.2010.04.036","abstract":[{"text":"In metazoa, nuclear pore complexes (NPCs) assemble from disassembled precursors into a reforming nuclear envelope (NE) at the end of mitosis and into growing intact NEs during interphase. Here, we show via RNAi-mediated knockdown that ELYS, a nucleoporin critical for the recruitment of the essential Nup107/160 complex to chromatin, is required for NPC assembly at the end of mitosis but not during interphase. Conversely, the transmembrane nucleoporin POM121 is critical for the incorporation of the Nup107/160 complex into new assembly sites specifically during interphase. Strikingly, recruitment of the Nup107/160 complex to an intact NE involves a membrane curvature-sensing domain of its constituent Nup133, which is not required for postmitotic NPC formation. Our results suggest that in organisms with open mitosis, NPCs assemble via two distinct mechanisms to accommodate cell cycle-dependent differences in NE topology.","lang":"eng"}],"day":"11","quality_controlled":"1","_id":"11101","keyword":["General Biochemistry","Genetics and Molecular Biology"],"doi":"10.1016/j.cell.2010.04.036","publisher":"Elsevier","publication":"Cell","status":"public","page":"1030-1041","language":[{"iso":"eng"}],"author":[{"first_name":"Christine M.","last_name":"Doucet","full_name":"Doucet, Christine M."},{"full_name":"Talamas, Jessica A.","last_name":"Talamas","first_name":"Jessica A."},{"first_name":"Martin W","full_name":"HETZER, Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","last_name":"HETZER"}],"publication_status":"published","intvolume":"       141","title":"Cell cycle-dependent differences in nuclear pore complex assembly in metazoa","article_processing_charge":"No","pmid":1,"date_published":"2010-06-11T00:00:00Z","volume":141},{"article_processing_charge":"No","intvolume":"       140","title":"Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes","author":[{"first_name":"Maya","last_name":"Capelson","full_name":"Capelson, Maya"},{"last_name":"Liang","full_name":"Liang, Yun","first_name":"Yun"},{"first_name":"Roberta","full_name":"Schulte, Roberta","last_name":"Schulte"},{"first_name":"William","last_name":"Mair","full_name":"Mair, William"},{"last_name":"Wagner","full_name":"Wagner, Ulrich","first_name":"Ulrich"},{"first_name":"Martin W","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","full_name":"HETZER, Martin W","last_name":"HETZER"}],"publication_status":"published","volume":140,"date_published":"2010-02-05T00:00:00Z","pmid":1,"status":"public","page":"372-383","publication":"Cell","language":[{"iso":"eng"}],"keyword":["General Biochemistry","Genetics and Molecular Biology"],"_id":"11102","publisher":"Elsevier","doi":"10.1016/j.cell.2009.12.054","fulldoi":"https://doi.org/10.1016/j.cell.2009.12.054","issue":"3","quality_controlled":"1","day":"05","abstract":[{"text":"Nuclear pore complexes have recently been shown to play roles in gene activation; however their potential involvement in metazoan transcription remains unclear. Here we show that the nucleoporins Sec13, Nup98, and Nup88, as well as a group of FG-repeat nucleoporins, bind to the Drosophila genome at functionally distinct loci that often do not represent nuclear envelope contact sites. Whereas Nup88 localizes to silent loci, Sec13, Nup98, and a subset of FG-repeat nucleoporins bind to developmentally regulated genes undergoing transcription induction. Strikingly, RNAi-mediated knockdown of intranuclear Sec13 and Nup98 specifically inhibits transcription of their target genes and prevents efficient reactivation of transcription after heat shock, suggesting an essential role of NPC components in regulating complex gene expression programs of multicellular organisms.","lang":"eng"}],"date_created":"2022-04-07T07:53:36Z","citation":{"ieee":"M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, and M. Hetzer, “Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes,” <i>Cell</i>, vol. 140, no. 3. Elsevier, pp. 372–383, 2010.","chicago":"Capelson, Maya, Yun Liang, Roberta Schulte, William Mair, Ulrich Wagner, and Martin Hetzer. “Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes.” <i>Cell</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.cell.2009.12.054\">https://doi.org/10.1016/j.cell.2009.12.054</a>.","ama":"Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer M. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. <i>Cell</i>. 2010;140(3):372-383. doi:<a href=\"https://doi.org/10.1016/j.cell.2009.12.054\">10.1016/j.cell.2009.12.054</a>","short":"M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, M. Hetzer, Cell 140 (2010) 372–383.","ista":"Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer M. 2010. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell. 140(3), 372–383.","apa":"Capelson, M., Liang, Y., Schulte, R., Mair, W., Wagner, U., &#38; Hetzer, M. (2010). Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2009.12.054\">https://doi.org/10.1016/j.cell.2009.12.054</a>","mla":"Capelson, Maya, et al. “Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes.” <i>Cell</i>, vol. 140, no. 3, Elsevier, 2010, pp. 372–83, doi:<a href=\"https://doi.org/10.1016/j.cell.2009.12.054\">10.1016/j.cell.2009.12.054</a>."},"oa":1,"date_updated":"2024-10-14T11:28:14Z","article_type":"original","main_file_link":[{"url":"https://doi.org/10.1016/j.cell.2009.12.054","open_access":"1"}],"oa_version":"Published Version","scopus_import":"1","external_id":{"pmid":["20144761"]},"month":"02","year":"2010","extern":"1","publication_identifier":{"issn":["0092-8674"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article"},{"_id":"11753","scopus_import":"1","oa_version":"None","doi":"10.1109/icsd.2010.5568033","publisher":"Institute of Electrical and Electronics Engineers","month":"06","year":"2010","conference":{"location":"Potsdam, Germany","end_date":"2010-06-09","name":"ICSD: International Conference on Solid Dielectrics","start_date":"2010-06-04"},"fulldoi":"https://doi.org/10.1109/icsd.2010.5568033","extern":"1","quality_controlled":"1","publication_identifier":{"issn":["1553-5282"],"eissn":["2159-1687"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Ferroelectric ceramic materials have a wide range of applications because of their piezoelectric and pyroelectric properties. One of their most important physical properties is the specific heat. In this study, the specific heats of a series of lead-zirconate-titanate (PZT) compositions in the vicinity of the morphotropic phase boundary (MPB) were measured. The temperature range was from 1.8 to 300 K. It is believed that these are the lowest temperature measurements ever made on PZT. Differences between the specific heats of the different compositions were very small. However, the calculated Debye temperatures were slightly different. The results are useful in computing design parameters for technical devices.","lang":"eng"}],"type":"conference","day":"01","date_created":"2022-08-08T09:00:17Z","title":"Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary","article_processing_charge":"No","publication_status":"published","author":[{"first_name":"S. B.","last_name":"Lang","full_name":"Lang, S. B."},{"first_name":"J. C.","full_name":"Lashley, J. C.","last_name":"Lashley"},{"full_name":"Modic, Kimberly A","orcid":"0000-0001-9760-3147","last_name":"Modic","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","first_name":"Kimberly A"},{"first_name":"R. A.","full_name":"Fisher, R. A.","last_name":"Fisher"},{"last_name":"Zhu","full_name":"Zhu, W. M.","first_name":"W. M."},{"first_name":"Z. G.","full_name":"Ye, Z. G.","last_name":"Ye"}],"date_published":"2010-06-01T00:00:00Z","citation":{"ama":"Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. In: <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>. Institute of Electrical and Electronics Engineers; 2010. doi:<a href=\"https://doi.org/10.1109/icsd.2010.5568033\">10.1109/icsd.2010.5568033</a>","short":"S.B. Lang, J.C. Lashley, K.A. Modic, R.A. Fisher, W.M. Zhu, Z.G. Ye, in:, Proceedings of the 2010 IEEE International Conference on Solid Dielectrics, Institute of Electrical and Electronics Engineers, 2010.","mla":"Lang, S. B., et al. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic Phase Boundary.” <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>, 5568033, Institute of Electrical and Electronics Engineers, 2010, doi:<a href=\"https://doi.org/10.1109/icsd.2010.5568033\">10.1109/icsd.2010.5568033</a>.","apa":"Lang, S. B., Lashley, J. C., Modic, K. A., Fisher, R. A., Zhu, W. M., &#38; Ye, Z. G. (2010). Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. In <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>. Potsdam, Germany: Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/icsd.2010.5568033\">https://doi.org/10.1109/icsd.2010.5568033</a>","ista":"Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. 2010. Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. Proceedings of the 2010 IEEE International Conference on Solid Dielectrics. ICSD: International Conference on Solid Dielectrics, 5568033.","ieee":"S. B. Lang, J. C. Lashley, K. A. Modic, R. A. Fisher, W. M. Zhu, and Z. G. Ye, “Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary,” in <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>, Potsdam, Germany, 2010.","chicago":"Lang, S. B., J. C. Lashley, Kimberly A Modic, R. A. Fisher, W. M. Zhu, and Z. G. Ye. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic Phase Boundary.” In <i>Proceedings of the 2010 IEEE International Conference on Solid Dielectrics</i>. Institute of Electrical and Electronics Engineers, 2010. <a href=\"https://doi.org/10.1109/icsd.2010.5568033\">https://doi.org/10.1109/icsd.2010.5568033</a>."},"article_number":"5568033","publication":"Proceedings of the 2010 IEEE International Conference on Solid Dielectrics","date_updated":"2023-02-21T16:26:58Z","status":"public","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"11754"}]},"language":[{"iso":"eng"}]},{"year":"2010","conference":{"location":"Valletta, Malta","end_date":"2010-04-28","start_date":"2010-04-26","name":"MELECON: Mediterranean Electrotechnical Conference"},"extern":"1","fulldoi":"https://doi.org/10.1109/melcon.2010.5476345","quality_controlled":"1","publication_identifier":{"isbn":["978-142445795-3"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Ferroelectric ceramic materials have a wide range of applications because of their piezoelectric and pyroelectric properties. One of their most important physical properties is the specific heat. In this study, the specific heats of a series of lead-zirconate-titanate (PZT) compositions in the vicinity of the morphotropic phase boundary (MPB) were measured. The temperature range was from 1.8 to 300 K. It is believed that these are the lowest temperature measurements ever made on PZT. Differences between the specific heats of the different compositions were very small. However, the calculated Debye temperatures were slightly different. The results are useful in computing design parameters for technical devices.","lang":"eng"}],"type":"conference","day":"26","_id":"11754","scopus_import":"1","oa_version":"None","doi":"10.1109/melcon.2010.5476345","publisher":"Institute of Electrical and Electronics Engineers","month":"04","article_number":"5476345","publication":"15th IEEE Mediterranean Electrotechnical Conference","date_updated":"2023-02-21T16:26:55Z","status":"public","related_material":{"record":[{"id":"11753","relation":"later_version","status":"public"}]},"language":[{"iso":"eng"}],"title":"Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary","date_created":"2022-08-08T09:11:43Z","article_processing_charge":"No","author":[{"full_name":"Lang, S.B.","last_name":"Lang","first_name":"S.B."},{"full_name":"Lashley, J.C.","last_name":"Lashley","first_name":"J.C."},{"first_name":"Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","last_name":"Modic","orcid":"0000-0001-9760-3147","full_name":"Modic, Kimberly A"},{"first_name":"R.A.","last_name":"Fisher","full_name":"Fisher, R.A."},{"first_name":"W.M.","full_name":"Zhu, W.M.","last_name":"Zhu"},{"last_name":"Ye","full_name":"Ye, Z.G.","first_name":"Z.G."}],"publication_status":"published","date_published":"2010-04-26T00:00:00Z","citation":{"mla":"Lang, S. B., et al. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic Phase Boundary.” <i>15th IEEE Mediterranean Electrotechnical Conference</i>, 5476345, Institute of Electrical and Electronics Engineers, 2010, doi:<a href=\"https://doi.org/10.1109/melcon.2010.5476345\">10.1109/melcon.2010.5476345</a>.","apa":"Lang, S. B., Lashley, J. C., Modic, K. A., Fisher, R. A., Zhu, W. M., &#38; Ye, Z. G. (2010). Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. In <i>15th IEEE Mediterranean Electrotechnical Conference</i>. Valletta, Malta: Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/melcon.2010.5476345\">https://doi.org/10.1109/melcon.2010.5476345</a>","ista":"Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. 2010. Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. 15th IEEE Mediterranean Electrotechnical Conference. MELECON: Mediterranean Electrotechnical Conference, 5476345.","short":"S.B. Lang, J.C. Lashley, K.A. Modic, R.A. Fisher, W.M. Zhu, Z.G. Ye, in:, 15th IEEE Mediterranean Electrotechnical Conference, Institute of Electrical and Electronics Engineers, 2010.","ama":"Lang SB, Lashley JC, Modic KA, Fisher RA, Zhu WM, Ye ZG. Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary. In: <i>15th IEEE Mediterranean Electrotechnical Conference</i>. Institute of Electrical and Electronics Engineers; 2010. doi:<a href=\"https://doi.org/10.1109/melcon.2010.5476345\">10.1109/melcon.2010.5476345</a>","chicago":"Lang, S.B., J.C. Lashley, Kimberly A Modic, R.A. Fisher, W.M. Zhu, and Z.G. Ye. “Specific Heat of a Ferroelectric PZT Ceramic at the Morphotropic Phase Boundary.” In <i>15th IEEE Mediterranean Electrotechnical Conference</i>. Institute of Electrical and Electronics Engineers, 2010. <a href=\"https://doi.org/10.1109/melcon.2010.5476345\">https://doi.org/10.1109/melcon.2010.5476345</a>.","ieee":"S. B. Lang, J. C. Lashley, K. A. Modic, R. A. Fisher, W. M. Zhu, and Z. G. Ye, “Specific heat of a ferroelectric PZT ceramic at the morphotropic phase boundary,” in <i>15th IEEE Mediterranean Electrotechnical Conference</i>, Valletta, Malta, 2010."}},{"external_id":{"arxiv":["1001.5076"]},"month":"09","main_file_link":[{"url":"https://arxiv.org/abs/1001.5076","open_access":"1"}],"scopus_import":"1","oa_version":"Preprint","alternative_title":["LNCS"],"publication_identifier":{"issn":["1611-3349"],"isbn":["3642157742"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"conference","year":"2010","extern":"1","oa":1,"citation":{"chicago":"Feldman, Jon, Monika Henzinger, Nitish Korula, Vahab S. Mirrokni, and Cliff Stein. “Online Stochastic Packing Applied to Display Ad Allocation.” In <i>18th Annual European Symposium on Algorithms</i>, 6346:182–194. Springer Nature, 2010. <a href=\"https://doi.org/10.1007/978-3-642-15775-2_16\">https://doi.org/10.1007/978-3-642-15775-2_16</a>.","ieee":"J. Feldman, M. Henzinger, N. Korula, V. S. Mirrokni, and C. Stein, “Online stochastic packing applied to display ad allocation,” in <i>18th Annual European Symposium on Algorithms</i>, Liverpool, United Kingdom, 2010, vol. 6346, pp. 182–194.","mla":"Feldman, Jon, et al. “Online Stochastic Packing Applied to Display Ad Allocation.” <i>18th Annual European Symposium on Algorithms</i>, vol. 6346, Springer Nature, 2010, pp. 182–194, doi:<a href=\"https://doi.org/10.1007/978-3-642-15775-2_16\">10.1007/978-3-642-15775-2_16</a>.","apa":"Feldman, J., Henzinger, M., Korula, N., Mirrokni, V. S., &#38; Stein, C. (2010). Online stochastic packing applied to display ad allocation. In <i>18th Annual European Symposium on Algorithms</i> (Vol. 6346, pp. 182–194). Liverpool, United Kingdom: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-642-15775-2_16\">https://doi.org/10.1007/978-3-642-15775-2_16</a>","ista":"Feldman J, Henzinger M, Korula N, Mirrokni VS, Stein C. 2010. Online stochastic packing applied to display ad allocation. 18th Annual European Symposium on Algorithms. ESA: European Symposium on Algorithms, LNCS, vol. 6346, 182–194.","short":"J. Feldman, M. Henzinger, N. Korula, V.S. Mirrokni, C. Stein, in:, 18th Annual European Symposium on Algorithms, Springer Nature, 2010, pp. 182–194.","ama":"Feldman J, Henzinger M, Korula N, Mirrokni VS, Stein C. Online stochastic packing applied to display ad allocation. In: <i>18th Annual European Symposium on Algorithms</i>. Vol 6346. Springer Nature; 2010:182–194. doi:<a href=\"https://doi.org/10.1007/978-3-642-15775-2_16\">10.1007/978-3-642-15775-2_16</a>"},"date_created":"2022-08-11T12:14:20Z","arxiv":1,"date_updated":"2024-11-06T12:13:14Z","doi":"10.1007/978-3-642-15775-2_16","publisher":"Springer Nature","_id":"11797","quality_controlled":"1","abstract":[{"lang":"eng","text":"Inspired by online ad allocation, we study online stochastic packing integer programs from theoretical and practical standpoints. We first present a near-optimal online algorithm for a general class of packing integer programs which model various online resource allocation problems including online variants of routing, ad allocations, generalized assignment, and combinatorial auctions. As our main theoretical result, we prove that a simple dual training-based algorithm achieves a (1 − o(1))-approximation guarantee in the random order stochastic model. This is a significant improvement over logarithmic or constant-factor approximations for the adversarial variants of the same problems (e.g. factor 1−1𝑒 for online ad allocation, and log(m) for online routing). We then focus on the online display ad allocation problem and study the efficiency and fairness of various training-based and online allocation algorithms on data sets collected from real-life display ad allocation system. Our experimental evaluation confirms the effectiveness of training-based algorithms on real data sets, and also indicates an intrinsic trade-off between fairness and efficiency."}],"day":"01","conference":{"location":"Liverpool, United Kingdom","start_date":"2010-09-06","name":"ESA: European Symposium on Algorithms","end_date":"2010-09-08"},"fulldoi":"https://doi.org/10.1007/978-3-642-15775-2_16","date_published":"2010-09-01T00:00:00Z","volume":6346,"intvolume":"      6346","title":"Online stochastic packing applied to display ad allocation","article_processing_charge":"No","publication_status":"published","author":[{"last_name":"Feldman","full_name":"Feldman, Jon","first_name":"Jon"},{"first_name":"Monika H","full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","orcid":"0000-0002-5008-6530"},{"first_name":"Nitish","last_name":"Korula","full_name":"Korula, Nitish"},{"last_name":"Mirrokni","full_name":"Mirrokni, Vahab S.","first_name":"Vahab S."},{"first_name":"Cliff","last_name":"Stein","full_name":"Stein, Cliff"}],"language":[{"iso":"eng"}],"publication":"18th Annual European Symposium on Algorithms","page":"182–194","status":"public"},{"type":"conference","publication_identifier":{"issn":["1611-3349"],"isbn":["9783642130724"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","year":"2010","month":"05","scopus_import":"1","oa_version":"None","alternative_title":["LNCS"],"date_updated":"2024-11-06T08:15:13Z","citation":{"chicago":"Dütting, Paul, and Monika Henzinger. “Mechanisms for the Marriage and the Assignment Game.” In <i>7th International Conference on Algorithms and Complexity</i>, 6078:6–12. Springer Nature, 2010. <a href=\"https://doi.org/10.1007/978-3-642-13073-1_2\">https://doi.org/10.1007/978-3-642-13073-1_2</a>.","ieee":"P. Dütting and M. Henzinger, “Mechanisms for the marriage and the assignment game,” in <i>7th International Conference on Algorithms and Complexity</i>, Rome, Italy, 2010, vol. 6078, pp. 6–12.","ista":"Dütting P, Henzinger M. 2010. Mechanisms for the marriage and the assignment game. 7th International Conference on Algorithms and Complexity. CIAC: International Conference on Algorithms and Complexity, LNCS, vol. 6078, 6–12.","mla":"Dütting, Paul, and Monika Henzinger. “Mechanisms for the Marriage and the Assignment Game.” <i>7th International Conference on Algorithms and Complexity</i>, vol. 6078, Springer Nature, 2010, pp. 6–12, doi:<a href=\"https://doi.org/10.1007/978-3-642-13073-1_2\">10.1007/978-3-642-13073-1_2</a>.","apa":"Dütting, P., &#38; Henzinger, M. (2010). Mechanisms for the marriage and the assignment game. In <i>7th International Conference on Algorithms and Complexity</i> (Vol. 6078, pp. 6–12). Rome, Italy: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-642-13073-1_2\">https://doi.org/10.1007/978-3-642-13073-1_2</a>","ama":"Dütting P, Henzinger M. Mechanisms for the marriage and the assignment game. In: <i>7th International Conference on Algorithms and Complexity</i>. Vol 6078. Springer Nature; 2010:6–12. doi:<a href=\"https://doi.org/10.1007/978-3-642-13073-1_2\">10.1007/978-3-642-13073-1_2</a>","short":"P. Dütting, M. Henzinger, in:, 7th International Conference on Algorithms and Complexity, Springer Nature, 2010, pp. 6–12."},"date_created":"2022-08-11T12:27:43Z","abstract":[{"lang":"eng","text":"Starting with two models fifty years ago, the discrete marriage game [1] and the continuous assignment game [2], the study of stable matchings has evolved into a rich theory with applications in many areas. Most notably, it has lead to a number of truthful mechanisms that have seen a recent rejuvenation in the context of sponsored search. In this paper we survey the history of these problems and provide several links to ongoing research in the field."}],"day":"01","quality_controlled":"1","conference":{"location":"Rome, Italy","start_date":"2010-05-26","name":"CIAC: International Conference on Algorithms and Complexity","end_date":"2010-05-28"},"fulldoi":"https://doi.org/10.1007/978-3-642-13073-1_2","doi":"10.1007/978-3-642-13073-1_2","publisher":"Springer Nature","_id":"11798","language":[{"iso":"eng"}],"publication":"7th International Conference on Algorithms and Complexity","status":"public","page":"6–12","date_published":"2010-05-01T00:00:00Z","volume":6078,"publication_status":"published","author":[{"first_name":"Paul","last_name":"Dütting","full_name":"Dütting, Paul"},{"first_name":"Monika H","full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger"}],"intvolume":"      6078","title":"Mechanisms for the marriage and the assignment game","article_processing_charge":"No"},{"_id":"11838","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","doi":"10.4230/LIPICS.STACS.2010.2463","fulldoi":"https://doi.org/10.4230/LIPICS.STACS.2010.2463","conference":{"end_date":"2010-03-06","start_date":"2010-03-04","name":"STACS: Symposium on Theoretical Aspects of Computer Science","location":"Nancy, France"},"quality_controlled":"1","day":"09","abstract":[{"lang":"eng","text":"Two-sided matching markets play a prominent role in economic theory. A prime example of such a market is the sponsored search market where $n$ advertisers compete for the assignment of one of $k$ sponsored search results, also known as ``slots'', for certain keywords they are interested in. Here, as in other markets of that kind, market equilibria correspond to stable matchings. In this paper, we show how to modify Kuhn's Hungarian Method (Kuhn, 1955) so that it finds an optimal stable matching between advertisers and advertising slots in settings with generalized linear utilities, per-bidder-item reserve prices, and per-bidder-item maximum prices. The only algorithm for this problem presented so far (Aggarwal et al., 2009) requires the market to be in ''general position''. We do not make this assumption."}],"article_processing_charge":"No","title":"Sponsored search, market equilibria, and the Hungarian Method","intvolume":"         5","author":[{"full_name":"Dütting, Paul","last_name":"Dütting","first_name":"Paul"},{"full_name":"Henzinger, Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","orcid":"0000-0002-5008-6530","first_name":"Monika H"},{"first_name":"Ingmar","last_name":"Weber","full_name":"Weber, Ingmar"}],"publication_status":"published","date_published":"2010-03-09T00:00:00Z","volume":5,"page":"287-298","status":"public","publication":"27th International Symposium on Theoretical Aspects of Computer Science","language":[{"iso":"eng"}],"related_material":{"record":[{"status":"public","relation":"earlier_version","id":"11838"}]},"main_file_link":[{"url":"https://doi.org/10.4230/LIPIcs.STACS.2010.2463","open_access":"1"}],"alternative_title":["LIPIcs"],"oa_version":"Published Version","scopus_import":"1","external_id":{"arxiv":["0912.1934"]},"month":"03","year":"2010","extern":"1","publication_identifier":{"issn":["1868-8969"],"isbn":["978-3-939897-16-3"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"conference","date_created":"2022-08-12T11:45:49Z","arxiv":1,"citation":{"ieee":"P. Dütting, M. Henzinger, and I. Weber, “Sponsored search, market equilibria, and the Hungarian Method,” in <i>27th International Symposium on Theoretical Aspects of Computer Science</i>, Nancy, France, 2010, vol. 5, pp. 287–298.","chicago":"Dütting, Paul, Monika Henzinger, and Ingmar Weber. “Sponsored Search, Market Equilibria, and the Hungarian Method.” In <i>27th International Symposium on Theoretical Aspects of Computer Science</i>, 5:287–98. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010. <a href=\"https://doi.org/10.4230/LIPICS.STACS.2010.2463\">https://doi.org/10.4230/LIPICS.STACS.2010.2463</a>.","short":"P. Dütting, M. Henzinger, I. Weber, in:, 27th International Symposium on Theoretical Aspects of Computer Science, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010, pp. 287–298.","ama":"Dütting P, Henzinger M, Weber I. Sponsored search, market equilibria, and the Hungarian Method. In: <i>27th International Symposium on Theoretical Aspects of Computer Science</i>. Vol 5. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2010:287-298. doi:<a href=\"https://doi.org/10.4230/LIPICS.STACS.2010.2463\">10.4230/LIPICS.STACS.2010.2463</a>","ista":"Dütting P, Henzinger M, Weber I. 2010. Sponsored search, market equilibria, and the Hungarian Method. 27th International Symposium on Theoretical Aspects of Computer Science. STACS: Symposium on Theoretical Aspects of Computer Science, LIPIcs, vol. 5, 287–298.","mla":"Dütting, Paul, et al. “Sponsored Search, Market Equilibria, and the Hungarian Method.” <i>27th International Symposium on Theoretical Aspects of Computer Science</i>, vol. 5, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2010, pp. 287–98, doi:<a href=\"https://doi.org/10.4230/LIPICS.STACS.2010.2463\">10.4230/LIPICS.STACS.2010.2463</a>.","apa":"Dütting, P., Henzinger, M., &#38; Weber, I. (2010). Sponsored search, market equilibria, and the Hungarian Method. In <i>27th International Symposium on Theoretical Aspects of Computer Science</i> (Vol. 5, pp. 287–298). Nancy, France: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPICS.STACS.2010.2463\">https://doi.org/10.4230/LIPICS.STACS.2010.2463</a>"},"oa":1,"date_updated":"2024-11-06T11:58:41Z"}]