[{"month":"11","quality_controlled":"1","article_number":"iyaf175","publisher":"Oxford University Press","publication_identifier":{"issn":["1943-2631"]},"day":"01","type":"journal_article","OA_place":"publisher","status":"public","oa":1,"language":[{"iso":"eng"}],"author":[{"id":"33AB266C-F248-11E8-B48F-1D18A9856A87","last_name":"Puixeu Sala","full_name":"Puixeu Sala, Gemma","orcid":"0000-0001-8330-1754","first_name":"Gemma"},{"id":"fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b","full_name":"Hayward, Laura","last_name":"Hayward","first_name":"Laura"}],"article_processing_charge":"Yes (via OA deal)","article_type":"original","PlanS_conform":"1","issue":"3","_id":"20330","corr_author":"1","acknowledgement":"We thank Tim Connallon for useful discussions and correspondence, Himani Sachdeva and Nick Barton for comments on the manuscript and the Scientific Computing unit at ISTA for technical support. GP is the recipient of a DOC Fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (DOC 25817) and received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant (agreement no. 665385). LH received funding from the European Research Council, under the HaplotypeStructure Grant (grant no. 101055327) to Nick Barton.","oa_version":"Published Version","scopus_import":"1","isi":1,"OA_type":"hybrid","title":"The relationship between sexual dimorphism and intersex correlation: Do models support intuition?","citation":{"chicago":"Puixeu Sala, Gemma, and Laura Hayward. “The Relationship between Sexual Dimorphism and Intersex Correlation: Do Models Support Intuition?” <i>Genetics</i>. Oxford University Press, 2025. <a href=\"https://doi.org/10.1093/genetics/iyaf175\">https://doi.org/10.1093/genetics/iyaf175</a>.","mla":"Puixeu Sala, Gemma, and Laura Hayward. “The Relationship between Sexual Dimorphism and Intersex Correlation: Do Models Support Intuition?” <i>Genetics</i>, vol. 231, no. 3, iyaf175, Oxford University Press, 2025, doi:<a href=\"https://doi.org/10.1093/genetics/iyaf175\">10.1093/genetics/iyaf175</a>.","short":"G. Puixeu Sala, L. Hayward, Genetics 231 (2025).","ieee":"G. Puixeu Sala and L. Hayward, “The relationship between sexual dimorphism and intersex correlation: Do models support intuition?,” <i>Genetics</i>, vol. 231, no. 3. Oxford University Press, 2025.","ama":"Puixeu Sala G, Hayward L. The relationship between sexual dimorphism and intersex correlation: Do models support intuition? <i>Genetics</i>. 2025;231(3). doi:<a href=\"https://doi.org/10.1093/genetics/iyaf175\">10.1093/genetics/iyaf175</a>","apa":"Puixeu Sala, G., &#38; Hayward, L. (2025). The relationship between sexual dimorphism and intersex correlation: Do models support intuition? <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyaf175\">https://doi.org/10.1093/genetics/iyaf175</a>","ista":"Puixeu Sala G, Hayward L. 2025. The relationship between sexual dimorphism and intersex correlation: Do models support intuition? Genetics. 231(3), iyaf175."},"has_accepted_license":"1","year":"2025","date_created":"2025-09-10T05:48:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-01-05T13:04:07Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":231,"date_published":"2025-11-01T00:00:00Z","project":[{"name":"Sexual conflict: resolution, constraints and biomedical implications","grant_number":"25817","_id":"9B9DFC9E-BA93-11EA-9121-9846C619BF3A"},{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","call_identifier":"H2020"},{"grant_number":"101055327","_id":"bd6958e0-d553-11ed-ba76-86eba6a76c00","name":"Understanding the evolution of continuous genomes"}],"ddc":["570"],"ec_funded":1,"abstract":[{"lang":"eng","text":"The evolution of sexual dimorphism (the difference in average trait values between females and males, SD), is often thought to be constrained by shared genetic architecture between the sexes. Indeed, it is commonly expected that SD should negatively correlate with the intersex correlation (the genetic correlation between effects of segregating variants in females and males, r fm), either because (1) traits with ancestrally low r fm are less constrained in their ability to respond to sex-specific selection and thus evolve to be more dimorphic, or because (2) sex-specific selection, driving sexual dimorphism evolution, also acts to reduce r fm. Despite the intuitive appeal and prominence of these ideas, their generality and the conditions in which they hold remain unclear. Here, we develop models incorporating sex-specific stabilizing selection, mutation and genetic drift to examine the relationship between r fm and SD. We show that the two commonly-discussed mechanisms with the potential to generate a negative correlation between SD and r fm could just as easily generate a positive association, since the standard line of reasoning hinges on a hidden assumption that sex-specific adaptation more frequently favors increased dimorphism than reduced dimorphism. Our results provide, to our knowledge, the first mechanistic framework for understanding the conditions under which a correlation between r fm and SD may arise and offer a compelling explanation for inconsistent empirical evidence. We also make the intriguing observation that—even when selection between the two sexes is identical—drift generates nonzero SD. We quantify this effect and discuss its significance."}],"doi":"10.1093/genetics/iyaf175","publication_status":"published","department":[{"_id":"BeVi"},{"_id":"NiBa"}],"external_id":{"isi":["001598595000001"]},"file":[{"checksum":"bbb73bbf8617812d4d8db4af92be9538","file_id":"20946","relation":"main_file","date_created":"2026-01-05T13:03:18Z","success":1,"content_type":"application/pdf","creator":"dernst","access_level":"open_access","file_size":1550562,"file_name":"2025_Genetics_Puixeu.pdf","date_updated":"2026-01-05T13:03:18Z"}],"intvolume":"       231","publication":"Genetics","file_date_updated":"2026-01-05T13:03:18Z"},{"date_updated":"2026-04-28T13:25:55Z","volume":6,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_published":"2025-09-02T00:00:00Z","ddc":["550"],"date_created":"2025-09-14T22:01:31Z","year":"2025","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","intvolume":"         6","file":[{"access_level":"open_access","file_name":"2025_CommEarthEnvir_Jouberton.pdf","file_size":3840094,"date_updated":"2025-09-15T08:16:09Z","creator":"dernst","date_created":"2025-09-15T08:16:09Z","success":1,"content_type":"application/pdf","checksum":"62f9740c6cf564879006f4d97b58b608","file_id":"20356","relation":"main_file"}],"publication":"Communications Earth and Environment","file_date_updated":"2025-09-15T08:16:09Z","doi":"10.1038/s43247-025-02611-8","abstract":[{"text":"Central Asia hosts some of the world’s last relatively healthy mountain glaciers and is heavily dependent on snow and ice melt for downstream water supply, though the causes of this stable glacier state are not known. We combine recent in-situ observations, climate reanalysis and remote sensing data to force a land-surface model to reconstruct glacier changes over the last two decades (1999–2023) and disentangle their causes over a benchmark glacierized catchment in Tajikistan. We show that snowfall and snow depth have been substantially lower since 2018, leading to a decline in glacier health and reduced runoff generation. Remote-sensing observations confirm wider snow depletion across the Northwestern Pamirs, suggesting that a lack of snowfall might be a cause of mass losses regionally. Our results provide an explanation for the recent decline in glacier health in the region, and reinforce the need to better understand the variability of precipitation.","lang":"eng"}],"department":[{"_id":"FrPe"}],"external_id":{"pmid":["40910036"],"isi":["001563848700001"]},"publication_status":"published","author":[{"first_name":"Achille","id":"f2426a39-920b-11f0-ac40-cbeda2086b9c","full_name":"Jouberton, Achille","last_name":"Jouberton"},{"first_name":"Thomas","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","full_name":"Shaw, Thomas","orcid":"0000-0001-7640-6152","last_name":"Shaw"},{"first_name":"Evan","last_name":"Miles","full_name":"Miles, Evan"},{"full_name":"Kneib, Marin","last_name":"Kneib","first_name":"Marin"},{"id":"86698d64-c4c6-11ee-af02-cdf1e6a7d31f","full_name":"Fugger, Stefan","last_name":"Fugger","first_name":"Stefan"},{"first_name":"Pascal","last_name":"Buri","full_name":"Buri, Pascal","id":"317987aa-9421-11ee-ac5a-b941b041abba"},{"first_name":"Michael","id":"22a2674a-61ce-11ee-94b5-d18813baf16f","last_name":"Mccarthy","full_name":"Mccarthy, Michael"},{"first_name":"Abdulhamid","full_name":"Kayumov, Abdulhamid","last_name":"Kayumov"},{"full_name":"Navruzshoev, Hofiz","last_name":"Navruzshoev","first_name":"Hofiz"},{"first_name":"Ardamehr","last_name":"Halimov","full_name":"Halimov, Ardamehr"},{"full_name":"Kabutov, Khusrav","last_name":"Kabutov","first_name":"Khusrav"},{"full_name":"Homidov, Farrukh","last_name":"Homidov","first_name":"Farrukh"},{"first_name":"Francesca","last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca","orcid":"0000-0002-5554-8087","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"language":[{"iso":"eng"}],"oa":1,"PlanS_conform":"1","DOAJ_listed":"1","_id":"20348","corr_author":"1","article_processing_charge":"Yes","article_type":"original","publication_identifier":{"eissn":["2662-4435"]},"article_number":"691","publisher":"Springer Nature","quality_controlled":"1","month":"09","OA_place":"publisher","status":"public","day":"02","type":"journal_article","has_accepted_license":"1","citation":{"mla":"Jouberton, Achille, et al. “Snowfall Decrease in Recent Years Undermines Glacier Health and Meltwater Resources in the Northwestern Pamirs.” <i>Communications Earth and Environment</i>, vol. 6, 691, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s43247-025-02611-8\">10.1038/s43247-025-02611-8</a>.","chicago":"Jouberton, Achille, Thomas Shaw, Evan Miles, Marin Kneib, Stefan Fugger, Pascal Buri, Michael McCarthy, et al. “Snowfall Decrease in Recent Years Undermines Glacier Health and Meltwater Resources in the Northwestern Pamirs.” <i>Communications Earth and Environment</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s43247-025-02611-8\">https://doi.org/10.1038/s43247-025-02611-8</a>.","apa":"Jouberton, A., Shaw, T., Miles, E., Kneib, M., Fugger, S., Buri, P., … Pellicciotti, F. (2025). Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs. <i>Communications Earth and Environment</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s43247-025-02611-8\">https://doi.org/10.1038/s43247-025-02611-8</a>","ista":"Jouberton A, Shaw T, Miles E, Kneib M, Fugger S, Buri P, McCarthy M, Kayumov A, Navruzshoev H, Halimov A, Kabutov K, Homidov F, Pellicciotti F. 2025. Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs. Communications Earth and Environment. 6, 691.","ama":"Jouberton A, Shaw T, Miles E, et al. Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs. <i>Communications Earth and Environment</i>. 2025;6. doi:<a href=\"https://doi.org/10.1038/s43247-025-02611-8\">10.1038/s43247-025-02611-8</a>","ieee":"A. Jouberton <i>et al.</i>, “Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs,” <i>Communications Earth and Environment</i>, vol. 6. Springer Nature, 2025.","short":"A. Jouberton, T. Shaw, E. Miles, M. Kneib, S. Fugger, P. Buri, M. McCarthy, A. Kayumov, H. Navruzshoev, A. Halimov, K. Kabutov, F. Homidov, F. Pellicciotti, Communications Earth and Environment 6 (2025)."},"pmid":1,"OA_type":"gold","isi":1,"oa_version":"Published Version","scopus_import":"1","acknowledgement":"This work was made possible with funding from the Swiss National Science Foundation (ASCENT Project 189890, Understanding snow, glacier and rivers response to climate in High Mountain Asia). It was also supported by the ERC Consolidator RAVEN project No. 772751, Rapid mass losses of debris-covered glaciers in High Mountain Asia. Fieldwork funding support for the repeated visits to Tajikistan was also received from the Swiss Polar Institute Flagship Programme PAMIR (SPI-FLAG-2021-001) and the Swiss National Science Foundation (HOPE Project 183633, High-elevation precipitation in High Mountain Asia). We would like to thank Firdavs Vosidov, Ubaydullo Ubaydulloev, Tojiddin Rasulzoda and Iskandarov Handullo from the Center for the Research of Glaciers, Tajik National Academy of Sciences (CRG-TAS), for their invaluable support over multiple field campaigns at the study site. We thank Nazrialo Sheralizoda, current director of CRG-TAS, and Tomas Saks from the University of Fribourg for their support in enabling and coordinating the ongoing collaborative monitoring and measurements at the site. Marin Kneib acknowledges the funding from the Swiss National Science Foundation (SNSF) under the Contribution of avalanches to glacier mass balance (CAIRN) Postdoc Mobility program (grant agreement P500PN_210739). We extend our thanks to Hamish Pritchard and Federico Covi at BAS for their help with the processing of lake water pressure data. Finally, we thank the photographer Jason Klimatsas for the photos he took which we use in Fig. 1b and Supplementary Fig. S1. Pleiades stereo imagery was acquired through the CNES ISIS programme.","related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/the-tipping-of-the-last-resilient-glaciers/"}]},"title":"Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs"},{"isi":1,"OA_type":"hybrid","acknowledgement":"We thank Carolina Camelo for making schematics for this review.","scopus_import":"1","oa_version":"Published Version","title":"Decoding zebrafish oogenesis: From primordial germ cell development to fertilization","has_accepted_license":"1","citation":{"ista":"Hofmann L, Heisenberg C-PJ. 2025. Decoding zebrafish oogenesis: From primordial germ cell development to fertilization. Seminars in Cell and Developmental Biology. 175, 103650.","apa":"Hofmann, L., &#38; Heisenberg, C.-P. J. (2025). Decoding zebrafish oogenesis: From primordial germ cell development to fertilization. <i>Seminars in Cell and Developmental Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.semcdb.2025.103650\">https://doi.org/10.1016/j.semcdb.2025.103650</a>","short":"L. Hofmann, C.-P.J. Heisenberg, Seminars in Cell and Developmental Biology 175 (2025).","ama":"Hofmann L, Heisenberg C-PJ. Decoding zebrafish oogenesis: From primordial germ cell development to fertilization. <i>Seminars in Cell and Developmental Biology</i>. 2025;175. doi:<a href=\"https://doi.org/10.1016/j.semcdb.2025.103650\">10.1016/j.semcdb.2025.103650</a>","ieee":"L. Hofmann and C.-P. J. Heisenberg, “Decoding zebrafish oogenesis: From primordial germ cell development to fertilization,” <i>Seminars in Cell and Developmental Biology</i>, vol. 175. Elsevier, 2025.","chicago":"Hofmann, Laura, and Carl-Philipp J Heisenberg. “Decoding Zebrafish Oogenesis: From Primordial Germ Cell Development to Fertilization.” <i>Seminars in Cell and Developmental Biology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.semcdb.2025.103650\">https://doi.org/10.1016/j.semcdb.2025.103650</a>.","mla":"Hofmann, Laura, and Carl-Philipp J. Heisenberg. “Decoding Zebrafish Oogenesis: From Primordial Germ Cell Development to Fertilization.” <i>Seminars in Cell and Developmental Biology</i>, vol. 175, 103650, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.semcdb.2025.103650\">10.1016/j.semcdb.2025.103650</a>."},"pmid":1,"article_number":"103650","publication_identifier":{"eissn":["1096-3634"],"issn":["1084-9521"]},"publisher":"Elsevier","month":"12","quality_controlled":"1","status":"public","OA_place":"publisher","type":"journal_article","day":"01","author":[{"id":"b88d43f2-dc74-11ea-a0a7-e41b7912e031","full_name":"Hofmann, Laura","last_name":"Hofmann","first_name":"Laura"},{"last_name":"Heisenberg","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J"}],"oa":1,"language":[{"iso":"eng"}],"_id":"20349","corr_author":"1","PlanS_conform":"1","article_type":"review","article_processing_charge":"Yes (via OA deal)","doi":"10.1016/j.semcdb.2025.103650","abstract":[{"text":"Oogenesis – the formation and development of an oocyte – is fundamental to reproduction and embryonic development. Due to its accessibility to genetic manipulations and the ability to culture and experimentally manipulate oocytes ex vivo, zebrafish has emerged as a powerful vertebrate model system for studying oogenesis. In this review, we provide a comprehensive overview of zebrafish oogenesis, from early germ cell formation to oocyte maturation and fertilization. We discuss recent advances in uncovering the molecular and cellular mechanisms driving this complex process and highlight key knowledge gaps that remain to be addressed.","lang":"eng"}],"external_id":{"pmid":["40913907"],"isi":["001567260100001"]},"department":[{"_id":"CaHe"}],"publication_status":"published","intvolume":"       175","publication":"Seminars in Cell and Developmental Biology","file":[{"file_size":2778561,"date_updated":"2025-12-30T10:21:00Z","file_name":"2025_SemCellDevBiology_Hofmann.pdf","access_level":"open_access","creator":"dernst","content_type":"application/pdf","success":1,"date_created":"2025-12-30T10:21:00Z","relation":"main_file","file_id":"20914","checksum":"80ea6cbb004853bb1e87db3422a74aca"}],"file_date_updated":"2025-12-30T10:21:00Z","date_created":"2025-09-14T22:01:32Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":175,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2025-12-30T10:21:13Z","ddc":["570"],"date_published":"2025-12-01T00:00:00Z"},{"doi":"10.1051/0004-6361/202452885","abstract":[{"lang":"eng","text":"Context. Rotation plays an important role in stellar evolution. However, the mechanisms behind the transport of angular momentum in stars at various stages of their evolution are not well understood. To improve our understanding of these processes, it is necessary to measure and validate the internal rotation profiles of stars across different stages of evolution and mass regimes.\r\nAims. Our aim is to constrain the internal rotation profile of the 12-M⊙ β Cep pulsator HD 192575 from the observed pulsational multiplets and the asymmetries of their component frequencies.\r\nMethods. We updated the forward asteroseismic modelling of HD 192575 based on new TESS observations. We inverted the rotation profile from the symmetric part of the splittings and computed the multiplet asymmetries due to the Coriolis force and stellar deformation, which we treated perturbatively. We compared the computed asymmetries with the observed asymmetries.\r\nResults. Our new forward asteroseismic modelling is in agreement with previous results but with increased uncertainties, partially due to increased frequency precision, which required us to relax certain constraints. Ambiguity in the mode identification is the main source of the uncertainty, which also affects the inferred rotation profiles. Almost all acceptable rotation profiles occur in the regime below 0.4 d−1 and favour weak radial differential rotation, with a ratio of core to envelope rotation of less than 2. We find that the quality of the match between the observed and theoretically predicted mode asymmetries is strongly dependent on the mode identification and the internal structure of the star.\r\nConclusions. Our results offer the first detailed rotation inversion for a β Cep pulsator. They show that the rotation profile and the mode asymmetries provide a valuable tool for further constraining the evolutionary properties of HD 192575, and in particular the details of angular momentum transport in massive stars."}],"ec_funded":1,"external_id":{"isi":["001561561200007"],"arxiv":["2506.19948"]},"department":[{"_id":"LiBu"}],"publication_status":"published","intvolume":"       701","file":[{"creator":"dernst","access_level":"open_access","file_size":3175077,"file_name":"2025_AstronomyAstrophysics_Vanlaer.pdf","date_updated":"2025-09-15T06:58:09Z","file_id":"20354","checksum":"9ee9f34cf86305602d6cb3e07a1cc1a6","relation":"main_file","date_created":"2025-09-15T06:58:09Z","content_type":"application/pdf","success":1}],"publication":"Astronomy & Astrophysics","file_date_updated":"2025-09-15T06:58:09Z","date_created":"2025-09-14T22:01:32Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":701,"date_updated":"2026-02-16T12:12:53Z","ddc":["520"],"project":[{"name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"name":"Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology","_id":"914d8549-16d5-11f0-9cad-bbe6324c93a9","grant_number":"101165631"}],"date_published":"2025-09-01T00:00:00Z","isi":1,"OA_type":"diamond","scopus_import":"1","acknowledgement":"The authors appreciated the critical comments from the\r\nreferee, which encouraged V.V. to embark upon a new code development\r\nsprint. V.V. gratefully acknowledges support from the Research Foundation\r\nFlanders (FWO) under grant agreement N◦1156923N (PhD Fellowship) and\r\nN\r\n◦K233724N (Travel grant). D.M.B. gratefully acknowledges support from\r\nthe Research Foundation Flanders (FWO; grant number: 1286521N), and UK\r\nResearch and Innovation (UKRI) in the form of a Frontier Research grant under\r\nthe UK government’s ERC Horizon Europe funding guarantee (SYMPHONY;\r\ngrant number: EP/Y031059/1), and a Royal Society University Research Fellowship (URF; grant number: URF\\R1\\231631). S.B.D. acknowledges funding from\r\nthe European Union’s Horizon 2020 research and innovation programme under\r\nthe Marie Skłodowska-Curie grant agreement No 101034413. L.B. gratefully\r\nacknowledges support from the European Research Council (ERC) under the\r\nHorizon Europe programme (Calcifer; Starting Grant agreement N◦101165631).\r\nS.M. acknowledges support from the PLATO CNES grant at CEA/DAp.C.A.\r\nacknowledges financial support from the Research Foundation Flanders (FWO)\r\nunder grant K802922N (Sabbatical leave); she is grateful for the kind hospitality\r\noffered by CEA/Saclay during her sabbatical work visits in the spring of 2023.\r\nThe research leading to these results has received funding from the European\r\nResearch Council (ERC) under the Horizon Europe programme (Synergy Grant\r\nagreement N◦101071505: 4D-STAR). While funded by the European Union,\r\nviews and opinions expressed are however those of the author(s) only and do\r\nnot necessarily reflect those of the European Union or the European Research\r\nCouncil. Neither the European Union nor the granting authority can be held\r\nresponsible for them. The TESS data presented in this paper were obtained from\r\nthe Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI), which is operated by the Association of Universities for\r\nResearch in Astronomy, Inc., under NASA contract NAS5-26555. Support to\r\nMAST for these data is provided by the NASA Office of Space Science via grant\r\nNAG5-7584 and by other grants and contracts. Funding for the TESS mission\r\nwas provided by the NASA Explorer Program.","oa_version":"Published Version","title":"Interior rotation modelling of the β Cep pulsator HD 192575 including multiplet asymmetries","has_accepted_license":"1","citation":{"ista":"Vanlaer V, Bowman DM, Burssens S, Das SB, Bugnet LA, Mathis S, Aerts C. 2025. Interior rotation modelling of the β Cep pulsator HD 192575 including multiplet asymmetries. Astronomy &#38; Astrophysics. 701, A5.","apa":"Vanlaer, V., Bowman, D. M., Burssens, S., Das, S. B., Bugnet, L. A., Mathis, S., &#38; Aerts, C. (2025). Interior rotation modelling of the β Cep pulsator HD 192575 including multiplet asymmetries. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202452885\">https://doi.org/10.1051/0004-6361/202452885</a>","ieee":"V. Vanlaer <i>et al.</i>, “Interior rotation modelling of the β Cep pulsator HD 192575 including multiplet asymmetries,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.","short":"V. Vanlaer, D.M. Bowman, S. Burssens, S.B. Das, L.A. Bugnet, S. Mathis, C. Aerts, Astronomy &#38; Astrophysics 701 (2025).","ama":"Vanlaer V, Bowman DM, Burssens S, et al. Interior rotation modelling of the β Cep pulsator HD 192575 including multiplet asymmetries. <i>Astronomy &#38; Astrophysics</i>. 2025;701. doi:<a href=\"https://doi.org/10.1051/0004-6361/202452885\">10.1051/0004-6361/202452885</a>","mla":"Vanlaer, V., et al. “Interior Rotation Modelling of the β Cep Pulsator HD 192575 Including Multiplet Asymmetries.” <i>Astronomy &#38; Astrophysics</i>, vol. 701, A5, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202452885\">10.1051/0004-6361/202452885</a>.","chicago":"Vanlaer, V., D. M. Bowman, S. Burssens, Srijan B Das, Lisa Annabelle Bugnet, S. Mathis, and C. Aerts. “Interior Rotation Modelling of the β Cep Pulsator HD 192575 Including Multiplet Asymmetries.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202452885\">https://doi.org/10.1051/0004-6361/202452885</a>."},"arxiv":1,"article_number":"A5","publisher":"EDP Sciences","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"quality_controlled":"1","month":"09","status":"public","OA_place":"publisher","type":"journal_article","day":"01","author":[{"first_name":"V.","full_name":"Vanlaer, V.","last_name":"Vanlaer"},{"full_name":"Bowman, D. M.","last_name":"Bowman","first_name":"D. M."},{"last_name":"Burssens","full_name":"Burssens, S.","first_name":"S."},{"last_name":"Das","full_name":"Das, Srijan B","orcid":"0000-0003-0896-7972","id":"9ce7c423-dacf-11ed-8942-e09c6cb27149","first_name":"Srijan B"},{"id":"d9edb345-f866-11ec-9b37-d119b5234501","orcid":"0000-0003-0142-4000","full_name":"Bugnet, Lisa Annabelle","last_name":"Bugnet","first_name":"Lisa Annabelle"},{"first_name":"S.","last_name":"Mathis","full_name":"Mathis, S."},{"last_name":"Aerts","full_name":"Aerts, C.","first_name":"C."}],"language":[{"iso":"eng"}],"oa":1,"_id":"20350","PlanS_conform":"1","article_type":"original","article_processing_charge":"No"},{"title":"Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned","oa_version":"Published Version","acknowledgement":"We thank A.-M. Lawrence-Dörner and B. Berkenfeld for technical assistance and the members of the Kümmel Lab for constructive feedback. We are grateful to C. Ungermann and L. Langemeyer for insightful discussions and to F. Barr for providing plasmids encoding Fuzzy, Inturned, Rab23, and Rsg1. The template clone Flag-ciBAR1 was a gift from K.-I. Takemaru (Addgene, plasmid #200440). We thank the Bloomington Drosophila Stock center (BDSC) and DSHB for providing fly stocks and antibodies. This work was supported by the German Research Foundation (DFG) through the grants SFB1557-P10 (D.K.), SFB1557-P11 (A.M.), and SFB1577-P6, PA517/12-2, PA517/14-1, PA517/15-1, and PA517/16-1 (A.P.). Cryo-EM data were collected at the infrastructure of the University of Osnabrück, funded by the DFG (project number 455249646). J.-H.S. was supported by the Friedrich-Ebert Foundation. M.L. acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement number 101045340).","scopus_import":"1","OA_type":"gold","isi":1,"pmid":1,"citation":{"chicago":"Wilmes, Stephan, Jesse Tönjes, Maik Drechsler, Anita Ruf, Jan Hannes Schäfer, Anna Lürick, Dovile Januliene, et al. “Mechanistic Adaptation of the Metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned.” <i>Science Advances</i>. AAAS, 2025. <a href=\"https://doi.org/10.1126/sciadv.adx2893\">https://doi.org/10.1126/sciadv.adx2893</a>.","mla":"Wilmes, Stephan, et al. “Mechanistic Adaptation of the Metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned.” <i>Science Advances</i>, vol. 11, no. 35, AAAS, 2025, p. eadx2893, doi:<a href=\"https://doi.org/10.1126/sciadv.adx2893\">10.1126/sciadv.adx2893</a>.","short":"S. Wilmes, J. Tönjes, M. Drechsler, A. Ruf, J.H. Schäfer, A. Lürick, D. Januliene, S. Apelt, D. Di Iorio, S.V. Wegner, M. Loose, A. Moeller, A. Paululat, D. Kümmel, Science Advances 11 (2025) eadx2893.","ama":"Wilmes S, Tönjes J, Drechsler M, et al. Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned. <i>Science Advances</i>. 2025;11(35):eadx2893. doi:<a href=\"https://doi.org/10.1126/sciadv.adx2893\">10.1126/sciadv.adx2893</a>","ieee":"S. Wilmes <i>et al.</i>, “Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned,” <i>Science Advances</i>, vol. 11, no. 35. AAAS, p. eadx2893, 2025.","ista":"Wilmes S, Tönjes J, Drechsler M, Ruf A, Schäfer JH, Lürick A, Januliene D, Apelt S, Di Iorio D, Wegner SV, Loose M, Moeller A, Paululat A, Kümmel D. 2025. Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned. Science Advances. 11(35), eadx2893.","apa":"Wilmes, S., Tönjes, J., Drechsler, M., Ruf, A., Schäfer, J. H., Lürick, A., … Kümmel, D. (2025). Mechanistic adaptation of the metazoan RabGEFs Mon1-Ccz1 and Fuzzy-Inturned. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.adx2893\">https://doi.org/10.1126/sciadv.adx2893</a>"},"has_accepted_license":"1","day":"29","type":"journal_article","OA_place":"publisher","status":"public","page":"eadx2893","month":"08","quality_controlled":"1","publisher":"AAAS","publication_identifier":{"eissn":["2375-2548"]},"article_processing_charge":"Yes","article_type":"original","PlanS_conform":"1","DOAJ_listed":"1","_id":"20351","issue":"35","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Wilmes","full_name":"Wilmes, Stephan","first_name":"Stephan"},{"first_name":"Jesse","last_name":"Tönjes","full_name":"Tönjes, Jesse"},{"last_name":"Drechsler","full_name":"Drechsler, Maik","first_name":"Maik"},{"first_name":"Anita","full_name":"Ruf, Anita","last_name":"Ruf"},{"first_name":"Jan Hannes","full_name":"Schäfer, Jan Hannes","last_name":"Schäfer"},{"full_name":"Lürick, Anna","last_name":"Lürick","first_name":"Anna"},{"first_name":"Dovile","full_name":"Januliene, Dovile","last_name":"Januliene"},{"first_name":"Steven","full_name":"Apelt, Steven","last_name":"Apelt"},{"first_name":"Daniele","full_name":"Di Iorio, Daniele","last_name":"Di Iorio"},{"first_name":"Seraphine V.","full_name":"Wegner, Seraphine V.","last_name":"Wegner"},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","last_name":"Loose","full_name":"Loose, Martin","orcid":"0000-0001-7309-9724","first_name":"Martin"},{"first_name":"Arne","last_name":"Moeller","full_name":"Moeller, Arne"},{"full_name":"Paululat, Achim","last_name":"Paululat","first_name":"Achim"},{"last_name":"Kümmel","full_name":"Kümmel, Daniel","first_name":"Daniel"}],"publication_status":"published","department":[{"_id":"MaLo"}],"external_id":{"pmid":["40864718"],"isi":["001559806100033"]},"abstract":[{"lang":"eng","text":"Rab GTPases organize intracellular trafficking and provide identity to organelles. Their spatiotemporal activation by guanine nucleotide exchange factors (GEFs) is tightly controlled to ensure fidelity. Our structural and functional comparison of the tri-longin domain RabGEFs Mon1-Ccz1 and Fuzzy-Inturned reveals the molecular basis for their target specificity. Both complexes rely on a conserved sequence motif of their substrate GTPases for the catalytic mechanism, while secondary interactions allow discrimination between targets. We also find that dimeric Mon1-Ccz1 from fungi and the metazoan homologs with the additional third subunit RMC1/Bulli bind membranes through electrostatic interactions via distinct interfaces. Protein-lipid interaction studies and functional characterization in flies reveal an essential function of RMC1/Bulli as mediator of GEF complex membrane recruitment. In the case of Fuzzy-Inturned, reconstitution experiments demonstrate that the BAR (Bin-Amphiphysin-Rvs) domain protein CiBAR1 can support membrane recruitment of the GEF. Collectively, our study demonstrates the molecular basis for the adaptation of TLD-RabGEFs to different cellular functions."}],"doi":"10.1126/sciadv.adx2893","file_date_updated":"2025-09-15T07:23:12Z","intvolume":"        11","publication":"Science Advances","file":[{"success":1,"content_type":"application/pdf","date_created":"2025-09-15T07:23:12Z","relation":"main_file","checksum":"a3de801f3c6c1deadd7099d965db799a","file_id":"20355","date_updated":"2025-09-15T07:23:12Z","file_name":"2025_ScienceAdvance_Wilmes.pdf","file_size":3434827,"access_level":"open_access","creator":"dernst"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2025","date_created":"2025-09-14T22:01:32Z","date_published":"2025-08-29T00:00:00Z","ddc":["570"],"project":[{"_id":"bd6ae2ca-d553-11ed-ba76-a4aa239da5ee","grant_number":"101045340","name":"Synthetic and structural biology of Rab GTPase networks"}],"date_updated":"2025-09-30T14:40:27Z","volume":11,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"}},{"abstract":[{"text":"At high metallicity, a majority of massive stars have at least one close stellar companion. The evolution of such binaries is subject to strong interaction processes, which heavily impact the characteristics of their life-ending supernova and compact remnants. For the low-metallicity environments of high-redshift galaxies, constraints on the multiplicity properties of massive stars over the separation range leading to binary interaction are crucially missing. Here we show that the presence of massive stars in close binaries is ubiquitous, even at low metallicity. Using the Very Large Telescope, we obtained multi-epoch radial velocity measurements of a representative sample of 139 massive O-type stars across the Small Magellanic Cloud, which has a metal content of about one-fifth of the solar value. We find that 45% of them show radial velocity variations that demonstrate that they are members of close binary systems, and predominantly have orbital periods shorter than 1 year. Correcting for observational biases indicates that at least 70+11−6 %  of the O stars in our sample are in close binaries, and that at least 68+7\r\n−8% of all O stars interact with a companion star during their lifetime. We found no evidence supporting a statistically significant trend of the multiplicity properties with metallicity. Our results indicate that multiplicity and binary interactions govern the evolution of massive stars and determine their cosmic feedback and explosive fates.","lang":"eng"}],"doi":"10.1038/s41550-025-02610-x","publication_status":"published","department":[{"_id":"YlGo"}],"external_id":{"isi":["001568077900001"],"arxiv":["2509.12488"]},"intvolume":"         9","publication":"Nature Astronomy","year":"2025","date_created":"2025-09-14T22:01:32Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2509.12488"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-12-30T10:27:05Z","volume":9,"date_published":"2025-09-02T00:00:00Z","scopus_import":"1","oa_version":"Preprint","acknowledgement":"Based on data collected at the European Southern Observatory (ESO) under programme ID 112.25R7. The research leading to these results has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 and Horizon Europe research and innovation programme (grant agreement numbers 772225: MULTIPLES, 772086: ASSESS and 945806: TEL-STARS, ADG101054731: Stellar-BHs-SDSS-V, and 101164755: METAL). This research was supported by the Israel Science Foundation (ISF) under grant number 0603225041. We acknowledge support from the Science and Technology Facilities Council (research grant ST/V000853/1 and ST/V000233/1), UK Research and Innovation (UKRI) and the UK government’s ERC Horizon Europe funding guarantee (grant number EP/Y031059/1), a Royal Society University Research Fellowship (grant number URF\\R1\\231631), a Royal Society–Science Foundation Ireland University Research Fellowship, the German Deutsche Forschungsgemeinschaft (Project-ID 496854903, 445674056 and 443790621, Germany’s Excellence Strategy EXC 2181/1-390900948), the Klaus Tschira Foundation, the JSPS Kakenhi Grant-in-Aid for Scientific Research (23K19071) and international fellowships (at the Graduate school of Science, Tokyo University), the Australian Research Council (ARC) Centre of Excellence for Gravitational Wave Discovery (OzGrav; project number CE230100016), the Deutsches Zentrum für Luft und Raumfahrt (DLR) grants FKZ 50OR2005 and 50OR2306, Agencia Española de Investigación (AEI) of the Spanish Ministerio de Ciencia Innovación y Universidades (MICIU) and the European Regional Development Fund, FEDER and Severo Ochoa Programme (grants PID2021-122397NB-C21 and CEX2019-000920-S), the NextGeneration EU/PRTR and MIU (UNI/551/2021) trough grant Margarita Salas-UL, the CAPES-Br and FAPERJ/DSC-10 (SEI-260003/001630/2023), MCIN/AEI/10.13039/501100011033 by ‘ERDF A way of making Europe’ (grants PID2019-105552RB-C41 and PID2022-137779OB-C41, PID2021-125485NB-C22, CEX2019-000918-M) funded by MCIN/AEI/10.13039/501100011033 (State Agency for Research of the Spanish Ministry of Science and Innovation) and SGR-2021-01069 (AGAUR), the Spanish Government Ministerio de Ciencia e Innovación and Agencia Estatal de Investigación (10.13 039/501 100 011 033; grant PID2022-136 640 NB-C22), the Consejo Superior de Investigaciones Científicas (CSIC; grant 2022-AEP 005), the Polish National Agency for Academic Exchange (BEKKER fellowship BPN/BEK/2022/1/00106) and National Science Center (NCN, Poland; grant number OPUS 2021/41/B/ST9/00757), the ‘La Caixa’ Foundation (ID 100010434) under the fellowship code LCF/BQ/PI23/11970035, the Research foundation Flanders (FWO) PhD fellowship under project 11E1721N and senior postdoctoral fellowship under number 12ZY523N, and the Netherlands Research Council NWO (VIDI 203.061 grant).","isi":1,"OA_type":"green","title":"A high fraction of close massive binary stars at low metallicity","arxiv":1,"citation":{"chicago":"Sana, H., T. Shenar, J. Bodensteiner, N. Britavskiy, N. Langer, D. J. Lennon, L. Mahy, et al. “A High Fraction of Close Massive Binary Stars at Low Metallicity.” <i>Nature Astronomy</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41550-025-02610-x\">https://doi.org/10.1038/s41550-025-02610-x</a>.","mla":"Sana, H., et al. “A High Fraction of Close Massive Binary Stars at Low Metallicity.” <i>Nature Astronomy</i>, vol. 9, Springer Nature, 2025, pp. 1337–46, doi:<a href=\"https://doi.org/10.1038/s41550-025-02610-x\">10.1038/s41550-025-02610-x</a>.","ieee":"H. Sana <i>et al.</i>, “A high fraction of close massive binary stars at low metallicity,” <i>Nature Astronomy</i>, vol. 9. Springer Nature, pp. 1337–1346, 2025.","short":"H. Sana, T. Shenar, J. Bodensteiner, N. Britavskiy, N. Langer, D.J. Lennon, L. Mahy, I. Mandel, S.E. De Mink, L.R. Patrick, J.I. Villaseñor, M. Dirickx, M. Abdul-Masih, L.A. Almeida, F. Backs, S.R. Berlanas, M. Bernini-Peron, D.M. Bowman, V.A. Bronner, P.A. Crowther, K. Deshmukh, C.J. Evans, M. Fabry, M. Gieles, A. Gilkis, G. González-Torà, G. Gräfener, Y.L.L. Götberg, C. Hawcroft, V. Hénault-Brunet, A. Herrero, G. Holgado, R.G. Izzard, A. De Koter, S. Janssens, C. Johnston, J. Josiek, S. Justham, V.M. Kalari, J. Klencki, J. Kubát, B. Kubátová, R.R. Lefever, J.T. Van Loon, B. Ludwig, J. Mackey, J. Maíz Apellániz, G. Maravelias, P. Marchant, T. Mazeh, A. Menon, M. Moe, F. Najarro, L.M. Oskinova, R. Ovadia, D. Pauli, M. Pawlak, V. Ramachandran, M. Renzo, D.F. Rocha, A.A.C. Sander, F.R.N. Schneider, A. Schootemeijer, E.C. Schösser, C. Schürmann, K. Sen, S. Shahaf, S. Simón-Díaz, L.A.C. Van Son, M. Stoop, S. Toonen, F. Tramper, R. Valli, A. Vigna-Gómez, J.S. Vink, C. Wang, R. Willcox, Nature Astronomy 9 (2025) 1337–1346.","ama":"Sana H, Shenar T, Bodensteiner J, et al. A high fraction of close massive binary stars at low metallicity. <i>Nature Astronomy</i>. 2025;9:1337-1346. doi:<a href=\"https://doi.org/10.1038/s41550-025-02610-x\">10.1038/s41550-025-02610-x</a>","ista":"Sana H, Shenar T, Bodensteiner J, Britavskiy N, Langer N, Lennon DJ, Mahy L, Mandel I, De Mink SE, Patrick LR, Villaseñor JI, Dirickx M, Abdul-Masih M, Almeida LA, Backs F, Berlanas SR, Bernini-Peron M, Bowman DM, Bronner VA, Crowther PA, Deshmukh K, Evans CJ, Fabry M, Gieles M, Gilkis A, González-Torà G, Gräfener G, Götberg YLL, Hawcroft C, Hénault-Brunet V, Herrero A, Holgado G, Izzard RG, De Koter A, Janssens S, Johnston C, Josiek J, Justham S, Kalari VM, Klencki J, Kubát J, Kubátová B, Lefever RR, Van Loon JT, Ludwig B, Mackey J, Maíz Apellániz J, Maravelias G, Marchant P, Mazeh T, Menon A, Moe M, Najarro F, Oskinova LM, Ovadia R, Pauli D, Pawlak M, Ramachandran V, Renzo M, Rocha DF, Sander AAC, Schneider FRN, Schootemeijer A, Schösser EC, Schürmann C, Sen K, Shahaf S, Simón-Díaz S, Van Son LAC, Stoop M, Toonen S, Tramper F, Valli R, Vigna-Gómez A, Vink JS, Wang C, Willcox R. 2025. A high fraction of close massive binary stars at low metallicity. Nature Astronomy. 9, 1337–1346.","apa":"Sana, H., Shenar, T., Bodensteiner, J., Britavskiy, N., Langer, N., Lennon, D. J., … Willcox, R. (2025). A high fraction of close massive binary stars at low metallicity. <i>Nature Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41550-025-02610-x\">https://doi.org/10.1038/s41550-025-02610-x</a>"},"quality_controlled":"1","month":"09","publication_identifier":{"eissn":["2397-3366"]},"publisher":"Springer Nature","day":"02","type":"journal_article","OA_place":"repository","page":"1337-1346","status":"public","oa":1,"language":[{"iso":"eng"}],"author":[{"first_name":"H.","last_name":"Sana","full_name":"Sana, H."},{"full_name":"Shenar, T.","last_name":"Shenar","first_name":"T."},{"full_name":"Bodensteiner, J.","last_name":"Bodensteiner","first_name":"J."},{"full_name":"Britavskiy, N.","last_name":"Britavskiy","first_name":"N."},{"first_name":"N.","full_name":"Langer, N.","last_name":"Langer"},{"full_name":"Lennon, D. J.","last_name":"Lennon","first_name":"D. J."},{"first_name":"L.","last_name":"Mahy","full_name":"Mahy, L."},{"last_name":"Mandel","full_name":"Mandel, I.","first_name":"I."},{"first_name":"S. E.","last_name":"De Mink","full_name":"De Mink, S. E."},{"last_name":"Patrick","full_name":"Patrick, L. R.","first_name":"L. R."},{"first_name":"J. I.","full_name":"Villaseñor, J. I.","last_name":"Villaseñor"},{"full_name":"Dirickx, M.","last_name":"Dirickx","first_name":"M."},{"first_name":"M.","last_name":"Abdul-Masih","full_name":"Abdul-Masih, M."},{"full_name":"Almeida, L. A.","last_name":"Almeida","first_name":"L. A."},{"last_name":"Backs","full_name":"Backs, F.","first_name":"F."},{"full_name":"Berlanas, S. R.","last_name":"Berlanas","first_name":"S. R."},{"first_name":"M.","full_name":"Bernini-Peron, M.","last_name":"Bernini-Peron"},{"last_name":"Bowman","full_name":"Bowman, D. M.","first_name":"D. M."},{"full_name":"Bronner, V. A.","last_name":"Bronner","first_name":"V. A."},{"last_name":"Crowther","full_name":"Crowther, P. A.","first_name":"P. A."},{"first_name":"K.","full_name":"Deshmukh, K.","last_name":"Deshmukh"},{"full_name":"Evans, C. J.","last_name":"Evans","first_name":"C. J."},{"first_name":"M.","last_name":"Fabry","full_name":"Fabry, M."},{"first_name":"M.","last_name":"Gieles","full_name":"Gieles, M."},{"first_name":"A.","last_name":"Gilkis","full_name":"Gilkis, A."},{"first_name":"G.","full_name":"González-Torà, G.","last_name":"González-Torà"},{"last_name":"Gräfener","full_name":"Gräfener, G.","first_name":"G."},{"id":"d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d","orcid":"0000-0002-6960-6911","full_name":"Götberg, Ylva Louise Linsdotter","last_name":"Götberg","first_name":"Ylva Louise Linsdotter"},{"first_name":"C.","full_name":"Hawcroft, C.","last_name":"Hawcroft"},{"first_name":"V.","full_name":"Hénault-Brunet, V.","last_name":"Hénault-Brunet"},{"first_name":"A.","last_name":"Herrero","full_name":"Herrero, A."},{"first_name":"G.","full_name":"Holgado, G.","last_name":"Holgado"},{"full_name":"Izzard, R. G.","last_name":"Izzard","first_name":"R. G."},{"first_name":"A.","last_name":"De Koter","full_name":"De Koter, A."},{"first_name":"S.","full_name":"Janssens, S.","last_name":"Janssens"},{"full_name":"Johnston, C.","last_name":"Johnston","first_name":"C."},{"first_name":"J.","last_name":"Josiek","full_name":"Josiek, J."},{"first_name":"S.","full_name":"Justham, S.","last_name":"Justham"},{"first_name":"V. M.","last_name":"Kalari","full_name":"Kalari, V. M."},{"first_name":"J.","last_name":"Klencki","full_name":"Klencki, J."},{"first_name":"J.","last_name":"Kubát","full_name":"Kubát, J."},{"first_name":"B.","last_name":"Kubátová","full_name":"Kubátová, B."},{"first_name":"R. R.","full_name":"Lefever, R. R.","last_name":"Lefever"},{"full_name":"Van Loon, J. Th","last_name":"Van Loon","first_name":"J. Th"},{"first_name":"B.","full_name":"Ludwig, B.","last_name":"Ludwig"},{"first_name":"J.","last_name":"Mackey","full_name":"Mackey, J."},{"first_name":"J.","full_name":"Maíz Apellániz, J.","last_name":"Maíz Apellániz"},{"first_name":"G.","full_name":"Maravelias, G.","last_name":"Maravelias"},{"last_name":"Marchant","full_name":"Marchant, P.","first_name":"P."},{"first_name":"T.","full_name":"Mazeh, T.","last_name":"Mazeh"},{"full_name":"Menon, A.","last_name":"Menon","first_name":"A."},{"full_name":"Moe, M.","last_name":"Moe","first_name":"M."},{"full_name":"Najarro, F.","last_name":"Najarro","first_name":"F."},{"first_name":"L. M.","full_name":"Oskinova, L. M.","last_name":"Oskinova"},{"full_name":"Ovadia, R.","last_name":"Ovadia","first_name":"R."},{"last_name":"Pauli","full_name":"Pauli, D.","first_name":"D."},{"first_name":"M.","last_name":"Pawlak","full_name":"Pawlak, M."},{"full_name":"Ramachandran, V.","last_name":"Ramachandran","first_name":"V."},{"last_name":"Renzo","full_name":"Renzo, M.","first_name":"M."},{"first_name":"D. F.","full_name":"Rocha, D. F.","last_name":"Rocha"},{"first_name":"A. A.C.","last_name":"Sander","full_name":"Sander, A. A.C."},{"full_name":"Schneider, F. R.N.","last_name":"Schneider","first_name":"F. R.N."},{"first_name":"A.","full_name":"Schootemeijer, A.","last_name":"Schootemeijer"},{"first_name":"E. C.","last_name":"Schösser","full_name":"Schösser, E. C."},{"full_name":"Schürmann, C.","last_name":"Schürmann","first_name":"C."},{"full_name":"Sen, K.","last_name":"Sen","first_name":"K."},{"first_name":"S.","full_name":"Shahaf, S.","last_name":"Shahaf"},{"full_name":"Simón-Díaz, S.","last_name":"Simón-Díaz","first_name":"S."},{"last_name":"Van Son","full_name":"Van Son, L. A.C.","first_name":"L. A.C."},{"first_name":"M.","last_name":"Stoop","full_name":"Stoop, M."},{"first_name":"S.","last_name":"Toonen","full_name":"Toonen, S."},{"first_name":"F.","last_name":"Tramper","full_name":"Tramper, F."},{"full_name":"Valli, R.","last_name":"Valli","first_name":"R."},{"last_name":"Vigna-Gómez","full_name":"Vigna-Gómez, A.","first_name":"A."},{"first_name":"J. S.","full_name":"Vink, J. S.","last_name":"Vink"},{"full_name":"Wang, C.","last_name":"Wang","first_name":"C."},{"last_name":"Willcox","full_name":"Willcox, R.","first_name":"R."}],"article_type":"original","article_processing_charge":"No","_id":"20352"},{"file_date_updated":"2025-09-26T07:29:11Z","file":[{"embargo_to":"open_access","access_level":"closed","file_size":7501548,"date_updated":"2025-09-26T07:29:11Z","file_name":"2025_David_Babic_Thesis.pdf","embargo":"2026-09-25","creator":"dbabic","date_created":"2025-09-24T13:43:14Z","content_type":"application/pdf","file_id":"20388","checksum":"5ecf274281a54a41e0288bc79edf7492","relation":"main_file"},{"relation":"source_file","checksum":"2703e548390de0a1af7a707137e8ab3b","file_id":"20389","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2025-09-24T13:43:14Z","creator":"dbabic","file_size":23206052,"date_updated":"2025-09-26T07:29:11Z","file_name":"Thesis_Babic_draft.docx","access_level":"closed"}],"department":[{"_id":"GradSch"},{"_id":"JiFr"},{"_id":"EvBe"}],"publication_status":"published","doi":"10.15479/AT-ISTA-20362","degree_awarded":"PhD","alternative_title":["ISTA Thesis"],"date_published":"2025-09-18T00:00:00Z","ddc":["580"],"date_updated":"2026-04-07T11:52:02Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2025-09-17T13:28:01Z","year":"2025","has_accepted_license":"1","citation":{"mla":"Babic, David. <i>Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20362\">10.15479/AT-ISTA-20362</a>.","chicago":"Babic, David. “Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20362\">https://doi.org/10.15479/AT-ISTA-20362</a>.","ieee":"D. Babic, “Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana,” Institute of Science and Technology Austria, 2025.","short":"D. Babic, Mechanisms of Auxin-Mediated Early Embryogenesis in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2025.","ama":"Babic D. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20362\">10.15479/AT-ISTA-20362</a>","apa":"Babic, D. (2025). <i>Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20362\">https://doi.org/10.15479/AT-ISTA-20362</a>","ista":"Babic D. 2025. Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana. Institute of Science and Technology Austria."},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"20187"}]},"title":"Mechanisms of auxin-mediated early embryogenesis in Arabidopsis thaliana","oa_version":"Published Version","_id":"20362","corr_author":"1","article_processing_charge":"No","supervisor":[{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva"}],"author":[{"last_name":"Babic","full_name":"Babic, David","id":"db566d23-f6e0-11ea-865d-e6f270e968e7","first_name":"David"}],"language":[{"iso":"eng"}],"OA_place":"publisher","status":"public","page":"116","day":"18","type":"dissertation","publisher":"Institute of Science and Technology Austria","publication_identifier":{"issn":["2663-337X"]},"month":"09"},{"file":[{"checksum":"4e2407bdabf8d53f399eb8a20d86218e","file_id":"20372","relation":"main_file","date_created":"2025-09-23T07:57:51Z","success":1,"content_type":"application/pdf","creator":"dernst","access_level":"open_access","date_updated":"2025-09-23T07:57:51Z","file_size":3599137,"file_name":"2025_ScienceAdvance_Carpentier.pdf"}],"publication":"Science Advances","intvolume":"        11","file_date_updated":"2025-09-23T07:57:51Z","doi":"10.1126/sciadv.adw4124","abstract":[{"lang":"eng","text":"The Huntingtin protein (HTT), named for its role in Huntington’s disease, has been best understood as a scaffolding protein that promotes vesicle transport by molecular motors along microtubules. Here, we show that HTT also interacts with the actin cytoskeleton, and its loss of function disturbs the morphology and function of the axonal growth cone. We demonstrate that HTT organizes F-actin into bundles. Cryo–electron tomography (cryo-ET) and subtomogram averaging (STA) structural analyses reveal that HTT’s N-terminal HEAT and Bridge domains wrap around F-actin, while the C-terminal HEAT domain is displaced; furthermore, HTT dimerizes via the N-HEAT domain to bridge parallel actin filaments separated by ~20 nanometers. Our study provides the structural basis for understanding how HTT interacts with and organizes the actin cytoskeleton."}],"department":[{"_id":"FlSc"}],"external_id":{"isi":["001575751700013"],"pmid":["40971423"]},"publication_status":"published","date_updated":"2026-05-20T08:20:27Z","APC_amount":"1395,61 EUR","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":11,"date_published":"2025-09-19T00:00:00Z","project":[{"_id":"9B954C5C-BA93-11EA-9121-9846C619BF3A","grant_number":"P33367","name":"Structure and isoform diversity of the Arp2/3 complex"},{"name":"In Situ Actin Structures via Hybrid Cryo-electron Microscopy","grant_number":"E435","_id":"7bd318a1-9f16-11ee-852c-cc9217763180"},{"grant_number":"CZI01","_id":"62909c6f-2b32-11ec-9570-e1476aab5308","name":"CryoMinflux-guided in-situ molecular census and structure determination"},{"name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","grant_number":"101076260","_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb"},{"_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","call_identifier":"FWF","name":"FWF Open Access Fund"}],"ddc":["570"],"date_created":"2025-09-22T08:00:52Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","citation":{"apa":"Carpentier, R., Kim, J., Capizzi, M., Kim, H., Fäßler, F., Hansen, J., … Humbert, S. (2025). Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.adw4124\">https://doi.org/10.1126/sciadv.adw4124</a>","ista":"Carpentier R, Kim J, Capizzi M, Kim H, Fäßler F, Hansen J, Kim MJ, Denarier E, Blot B, Degennaro M, Labou S, Arnal I, Marcaida MJ, Peraro MD, Kim D, Schur FK, Song J-J, Humbert S. 2025. Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization. Science Advances. 11(38), eadw4124.","short":"R. Carpentier, J. Kim, M. Capizzi, H. Kim, F. Fäßler, J. Hansen, M.J. Kim, E. Denarier, B. Blot, M. Degennaro, S. Labou, I. Arnal, M.J. Marcaida, M.D. Peraro, D. Kim, F.K. Schur, J.-J. Song, S. Humbert, Science Advances 11 (2025).","ama":"Carpentier R, Kim J, Capizzi M, et al. Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization. <i>Science Advances</i>. 2025;11(38). doi:<a href=\"https://doi.org/10.1126/sciadv.adw4124\">10.1126/sciadv.adw4124</a>","ieee":"R. Carpentier <i>et al.</i>, “Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization,” <i>Science Advances</i>, vol. 11, no. 38. AAAS, 2025.","chicago":"Carpentier, Rémi, Jaesung Kim, Mariacristina Capizzi, Hyeongju Kim, Florian Fäßler, Jesse Hansen, Min Jeong Kim, et al. “Structure of the Huntingtin F-Actin Complex Reveals Its Role in Cytoskeleton Organization.” <i>Science Advances</i>. AAAS, 2025. <a href=\"https://doi.org/10.1126/sciadv.adw4124\">https://doi.org/10.1126/sciadv.adw4124</a>.","mla":"Carpentier, Rémi, et al. “Structure of the Huntingtin F-Actin Complex Reveals Its Role in Cytoskeleton Organization.” <i>Science Advances</i>, vol. 11, no. 38, eadw4124, AAAS, 2025, doi:<a href=\"https://doi.org/10.1126/sciadv.adw4124\">10.1126/sciadv.adw4124</a>."},"pmid":1,"OA_type":"gold","isi":1,"scopus_import":"1","oa_version":"Published Version","acknowledgement":"We thank C. Cuveillier, J. Delaroche, T. Ferraro, and A. Zanchi for help with TIRF experiments, electron microscopy preparation, data analysis, and cell cultures, respectively; A. Antkowiak, C. Bosc, C. Fassier, A. Fourest-Lieuvin, and V. Brandt for helpful discussions. We acknowledge the contribution of the Photonic Imaging Center of Grenoble Institute Neuroscience which is part of the ISdV core facility and certified by the IBiSA label and ICM.Quant (RRID:SCR_026393) core facility of the Paris Brain Institute (ICM); the AniRA lentivector production facility from the CELPHEDIA Infrastructure and SFR Biosciences (UAR3444/CNRS, US8/Inserm, ENS de Lyon, UCBL); the Scientific Service Units (SSUs) of ISTA through resources provided by Scientific Computing (SciComp, A. Schloegl and S. Elefante); and the Electron Microscopy Facility (EMF, V.V. Hodirnau). The software programs used for the processing were supported by SBGrid (www.sbgrid.org). This work was supported by the Agence Nationale pour la Recherche (AXYON: ANR-18-CE16-0009-01, S.H.), Austrian Science Fund (FWF) grants (P33367, F.K.M.S.; E435, J.M.H.), ChanZuckerberg Initiative (CZI) grant (DAF2021-234754, F.K.M.S.), Hereditary Disease Foundation Research Grant (HDF 990846, M.C.), European Union (ERC: ActinID 101076260, F.K.M.S.), Fondation pour la Recherche Médicale (FRM: équipe labellisée DEQ202203014675, S.H.; PhD fellowship, FDT202001010865, R.C.), Korea Health Industry Development Institute (KHIDI) (Korea-Switzerland global research support grant: RS-2023-00266300, J.-J.S.), National Research Foundation (NRF) of Korea (Korea-Austria collaborative grant NRF-2019K1A3A1A181160, J.-J.S. and F.K.M.S.; NRF-2020R1A2B5B03001517 and RS-2024-00333346 and RS-2024-00436173, J.-J.S.; 2021R1C1C1006700, D.K.).","title":"Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization","author":[{"full_name":"Carpentier, Rémi","last_name":"Carpentier","first_name":"Rémi"},{"first_name":"Jaesung","full_name":"Kim, Jaesung","last_name":"Kim"},{"full_name":"Capizzi, Mariacristina","last_name":"Capizzi","first_name":"Mariacristina"},{"first_name":"Hyeongju","last_name":"Kim","full_name":"Kim, Hyeongju"},{"first_name":"Florian","id":"404F5528-F248-11E8-B48F-1D18A9856A87","full_name":"Fäßler, Florian","orcid":"0000-0001-7149-769X","last_name":"Fäßler"},{"orcid":"0000-0001-7967-2085","full_name":"Hansen, Jesse","last_name":"Hansen","id":"1063c618-6f9b-11ec-9123-f912fccded63","first_name":"Jesse"},{"last_name":"Kim","full_name":"Kim, Min Jeong","first_name":"Min Jeong"},{"first_name":"Eric","full_name":"Denarier, Eric","last_name":"Denarier"},{"first_name":"Béatrice","last_name":"Blot","full_name":"Blot, Béatrice"},{"first_name":"Marine","full_name":"Degennaro, Marine","last_name":"Degennaro"},{"last_name":"Labou","full_name":"Labou, Sophia","first_name":"Sophia"},{"last_name":"Arnal","full_name":"Arnal, Isabelle","first_name":"Isabelle"},{"first_name":"Maria J.","last_name":"Marcaida","full_name":"Marcaida, Maria J."},{"first_name":"Matteo Dal","last_name":"Peraro","full_name":"Peraro, Matteo Dal"},{"first_name":"Doory","last_name":"Kim","full_name":"Kim, Doory"},{"last_name":"Schur","orcid":"0000-0003-4790-8078","full_name":"Schur, Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM"},{"last_name":"Song","full_name":"Song, Ji-Joon","first_name":"Ji-Joon"},{"first_name":"Sandrine","last_name":"Humbert","full_name":"Humbert, Sandrine"}],"oa":1,"language":[{"iso":"eng"}],"PlanS_conform":"1","corr_author":"1","_id":"20370","DOAJ_listed":"1","issue":"38","article_type":"original","article_processing_charge":"Yes","article_number":"eadw4124","publisher":"AAAS","publication_identifier":{"issn":["2375-2548"]},"quality_controlled":"1","month":"09","OA_place":"publisher","status":"public","day":"19","type":"journal_article"},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":85,"date_updated":"2025-09-24T08:21:55Z","ddc":["570"],"date_published":"2025-08-07T00:00:00Z","year":"2025","date_created":"2025-09-23T08:56:13Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Molecular Cell","intvolume":"        85","file":[{"creator":"dernst","access_level":"open_access","date_updated":"2025-09-24T07:54:03Z","file_size":41813494,"file_name":"2025_MolecularCell_Chakraborty.pdf","file_id":"20386","checksum":"e60390ca629b350af3221d4718ca6534","relation":"main_file","date_created":"2025-09-24T07:54:03Z","success":1,"content_type":"application/pdf"}],"file_date_updated":"2025-09-24T07:54:03Z","abstract":[{"text":"Pioneer transcription factors (TFs) engage chromatinized DNA motifs. However, it is unclear how the resultant TF-nucleosome complexes are decoded by co-factors. In humans, the TF p53 regulates cell-cycle progression, apoptosis, and the DNA damage response, with a large fraction of p53-bound sites residing in nucleosome-harboring inaccessible chromatin. We examined the interaction of chromatin-bound p53 with co-factors belonging to the ubiquitin proteasome system (UPS). At two distinct motif locations on the nucleosome (super-helical location [SHL]−5.7 and SHL+5.9), the E3 ubiquitin ligase E6-E6AP was unable to bind nucleosome-engaged p53. The deubiquitinase USP7, on the other hand, readily engages nucleosome-bound p53 in vitro and in cells. A corresponding cryo-electron microscopy (cryo-EM) structure shows USP7 engaged with p53 and nucleosomes. Our work illustrates how chromatin imposes a co-factor-selective barrier for p53 interactors, whereby flexibly tethered interaction domains of co-factors and TFs govern compatibility between co-factors, TFs, and chromatin.","lang":"eng"}],"doi":"10.1016/j.molcel.2025.06.027","publication_status":"published","department":[{"_id":"AlMi"}],"language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Deyasini","full_name":"Chakraborty, Deyasini","last_name":"Chakraborty"},{"first_name":"Colby R.","last_name":"Sandate","full_name":"Sandate, Colby R."},{"first_name":"Luke","full_name":"Isbel, Luke","last_name":"Isbel"},{"last_name":"Kempf","full_name":"Kempf, Georg","first_name":"Georg"},{"full_name":"Weiss, Joscha","last_name":"Weiss","first_name":"Joscha"},{"last_name":"Cavadini","full_name":"Cavadini, Simone","first_name":"Simone"},{"last_name":"Kater","full_name":"Kater, Lukas","first_name":"Lukas"},{"full_name":"Seebacher, Jan","last_name":"Seebacher","first_name":"Jan"},{"first_name":"Zuzanna","last_name":"Kozicka","full_name":"Kozicka, Zuzanna"},{"first_name":"Lisa","last_name":"Stoos","full_name":"Stoos, Lisa"},{"last_name":"Grand","full_name":"Grand, Ralph S.","first_name":"Ralph S."},{"first_name":"Dirk","last_name":"Schübeler","full_name":"Schübeler, Dirk"},{"orcid":"0000-0002-6080-839X","full_name":"Michael, Alicia","last_name":"Michael","id":"6437c950-2a03-11ee-914d-d6476dd7b75c","first_name":"Alicia"},{"first_name":"Nicolas H.","last_name":"Thomä","full_name":"Thomä, Nicolas H."}],"article_processing_charge":"Yes (in subscription journal)","article_type":"original","issue":"15","_id":"20374","PlanS_conform":"1","month":"08","quality_controlled":"1","publisher":"Elsevier","publication_identifier":{"issn":["1097-2765"]},"type":"journal_article","day":"07","status":"public","page":"2919-2936.e12","OA_place":"publisher","citation":{"ama":"Chakraborty D, Sandate CR, Isbel L, et al. Nucleosomes specify co-factor access to p53. <i>Molecular Cell</i>. 2025;85(15):2919-2936.e12. doi:<a href=\"https://doi.org/10.1016/j.molcel.2025.06.027\">10.1016/j.molcel.2025.06.027</a>","short":"D. Chakraborty, C.R. Sandate, L. Isbel, G. Kempf, J. Weiss, S. Cavadini, L. Kater, J. Seebacher, Z. Kozicka, L. Stoos, R.S. Grand, D. Schübeler, A.K. Michael, N.H. Thomä, Molecular Cell 85 (2025) 2919–2936.e12.","ieee":"D. Chakraborty <i>et al.</i>, “Nucleosomes specify co-factor access to p53,” <i>Molecular Cell</i>, vol. 85, no. 15. Elsevier, p. 2919–2936.e12, 2025.","apa":"Chakraborty, D., Sandate, C. R., Isbel, L., Kempf, G., Weiss, J., Cavadini, S., … Thomä, N. H. (2025). Nucleosomes specify co-factor access to p53. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2025.06.027\">https://doi.org/10.1016/j.molcel.2025.06.027</a>","ista":"Chakraborty D, Sandate CR, Isbel L, Kempf G, Weiss J, Cavadini S, Kater L, Seebacher J, Kozicka Z, Stoos L, Grand RS, Schübeler D, Michael AK, Thomä NH. 2025. Nucleosomes specify co-factor access to p53. Molecular Cell. 85(15), 2919–2936.e12.","chicago":"Chakraborty, Deyasini, Colby R. Sandate, Luke Isbel, Georg Kempf, Joscha Weiss, Simone Cavadini, Lukas Kater, et al. “Nucleosomes Specify Co-Factor Access to P53.” <i>Molecular Cell</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.molcel.2025.06.027\">https://doi.org/10.1016/j.molcel.2025.06.027</a>.","mla":"Chakraborty, Deyasini, et al. “Nucleosomes Specify Co-Factor Access to P53.” <i>Molecular Cell</i>, vol. 85, no. 15, Elsevier, 2025, p. 2919–2936.e12, doi:<a href=\"https://doi.org/10.1016/j.molcel.2025.06.027\">10.1016/j.molcel.2025.06.027</a>."},"has_accepted_license":"1","oa_version":"Published Version","scopus_import":"1","acknowledgement":"We thank M. Schütz for laboratory management, organization, and assistance with manuscript editing. We are grateful to all Thomä and Schübeler lab members. We thank Ulrich Hassiepen from Novartis for his support and insightful discussions on the kinetic analysis. This work was supported by funding from the European Research Council (ERC), under the European Union’s H2020 research program (NucEM, grant no. 884331); the Swiss National Science Foundation (SNF, grant no. 310030_301206 and 310030_214852); Krebsforschung (KFS, grant no. KFS-5933-08-2023); Novartis Research Foundation (to N.H.T.); the Novartis Freenovation (grant no. FN23-0000000514 to C.R.S.); the National Health and Medical Research Council CJ Martin Fellowship (APP1148380); the EU Horizon 2020 Research and Innovation Program under the Marie Sklodowska-Curie grant (grant no. 748760); the South Australian immunoGENomics Cancer Institute grant funding from the Australian Government; and the Sylvia and Charles Viertel Charitable Foundation Senior Medical Research Fellowship (to L.I.).","OA_type":"hybrid","title":"Nucleosomes specify co-factor access to p53"},{"date_updated":"2026-04-14T09:50:52Z","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"date_published":"2025-09-24T00:00:00Z","ddc":["570"],"date_created":"2025-09-25T10:08:10Z","year":"2025","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","file":[{"date_created":"2025-09-30T14:33:17Z","content_type":"application/x-zip-compressed","file_id":"20413","checksum":"6bb5a7ce318dc3f7bd165f2523e77b89","relation":"source_file","access_level":"closed","file_size":41847994,"file_name":"2025-Kishi-Kasumi-Thesis.zip","date_updated":"2025-10-01T11:54:41Z","creator":"kkishi"},{"creator":"kkishi","file_name":"2025-Kishi-Kasumi-Thesis.pdf","date_updated":"2025-10-02T07:51:21Z","file_size":55747072,"embargo":"2026-09-30","access_level":"closed","embargo_to":"open_access","relation":"main_file","checksum":"88349b9177e1dcbe1242cd3884b36fdb","file_id":"20414","content_type":"application/pdf","date_created":"2025-09-30T14:33:22Z"}],"file_date_updated":"2025-10-02T07:51:21Z","degree_awarded":"PhD","doi":"10.15479/AT-ISTA-20393","alternative_title":["ISTA Thesis"],"department":[{"_id":"GradSch"},{"_id":"AnKi"},{"_id":"EdHa"}],"publication_status":"published","author":[{"first_name":"Kasumi","full_name":"Kishi, Kasumi","orcid":"0000-0001-6060-4795","last_name":"Kishi","id":"3065DFC4-F248-11E8-B48F-1D18A9856A87"}],"supervisor":[{"id":"3959A2A0-F248-11E8-B48F-1D18A9856A87","last_name":"Kicheva","full_name":"Kicheva, Anna","orcid":"0000-0003-4509-4998","first_name":"Anna"},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo","first_name":"Edouard B"}],"language":[{"iso":"eng"}],"corr_author":"1","_id":"20393","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"]},"publisher":"Institute of Science and Technology Austria","month":"09","OA_place":"publisher","status":"public","page":"102","day":"24","type":"dissertation","has_accepted_license":"1","citation":{"mla":"Kishi, Kasumi. <i>Regulation of Notochord and Floor Plate Size during Mouse Development</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20393\">10.15479/AT-ISTA-20393</a>.","chicago":"Kishi, Kasumi. “Regulation of Notochord and Floor Plate Size during Mouse Development.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20393\">https://doi.org/10.15479/AT-ISTA-20393</a>.","ama":"Kishi K. Regulation of notochord and floor plate size during mouse development. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20393\">10.15479/AT-ISTA-20393</a>","short":"K. Kishi, Regulation of Notochord and Floor Plate Size during Mouse Development, Institute of Science and Technology Austria, 2025.","ieee":"K. Kishi, “Regulation of notochord and floor plate size during mouse development,” Institute of Science and Technology Austria, 2025.","apa":"Kishi, K. (2025). <i>Regulation of notochord and floor plate size during mouse development</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20393\">https://doi.org/10.15479/AT-ISTA-20393</a>","ista":"Kishi K. 2025. Regulation of notochord and floor plate size during mouse development. Institute of Science and Technology Austria."},"oa_version":"Published Version","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"LifeSc"}],"title":"Regulation of notochord and floor plate size during mouse development","related_material":{"record":[{"id":"18481","status":"public","relation":"part_of_dissertation"}]}},{"month":"09","quality_controlled":"1","publication_identifier":{"eissn":["2041-1723"]},"article_number":"8447","publisher":"Springer Nature","type":"journal_article","day":"26","status":"public","OA_place":"publisher","language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Mukund","id":"3C5A959A-F248-11E8-B48F-1D18A9856A87","full_name":"Vasudevan, Mukund","last_name":"Vasudevan"},{"first_name":"Chaitanya S","last_name":"Paranjape","full_name":"Paranjape, Chaitanya S","id":"3D85B7C4-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Sitte, Michael Philip","last_name":"Sitte","id":"0ba0f1f2-9cfe-11f0-bee6-f95318d225b0","first_name":"Michael Philip"},{"first_name":"Gökhan","full_name":"Yalniz, Gökhan","orcid":"0000-0002-8490-9312","last_name":"Yalniz","id":"66E74FA2-D8BF-11E9-8249-8DE2E5697425"},{"first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87","last_name":"Hof","orcid":"0000-0003-2057-2754","full_name":"Hof, Björn"}],"article_processing_charge":"Yes","article_type":"original","corr_author":"1","_id":"20402","DOAJ_listed":"1","PlanS_conform":"1","oa_version":"Published Version","scopus_import":"1","acknowledgement":"This work was supported by a grant from the Simons Foundation (662960, BH). We thank Yohann Duguet for helpful discussions, Baofang Song for the initial adaptation of openpipeflow57 to the channel geometry, and Ashley P. Willis for openpipeflow57.","OA_type":"gold","isi":1,"title":"Aging and memory of transitional turbulence","citation":{"apa":"Vasudevan, M., Paranjape, C. S., Sitte, M. P., Yalniz, G., &#38; Hof, B. (2025). Aging and memory of transitional turbulence. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-63044-7\">https://doi.org/10.1038/s41467-025-63044-7</a>","ista":"Vasudevan M, Paranjape CS, Sitte MP, Yalniz G, Hof B. 2025. Aging and memory of transitional turbulence. Nature Communications. 16, 8447.","short":"M. Vasudevan, C.S. Paranjape, M.P. Sitte, G. Yalniz, B. Hof, Nature Communications 16 (2025).","ieee":"M. Vasudevan, C. S. Paranjape, M. P. Sitte, G. Yalniz, and B. Hof, “Aging and memory of transitional turbulence,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","ama":"Vasudevan M, Paranjape CS, Sitte MP, Yalniz G, Hof B. Aging and memory of transitional turbulence. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-63044-7\">10.1038/s41467-025-63044-7</a>","mla":"Vasudevan, Mukund, et al. “Aging and Memory of Transitional Turbulence.” <i>Nature Communications</i>, vol. 16, 8447, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-63044-7\">10.1038/s41467-025-63044-7</a>.","chicago":"Vasudevan, Mukund, Chaitanya S Paranjape, Michael Philip Sitte, Gökhan Yalniz, and Björn Hof. “Aging and Memory of Transitional Turbulence.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-63044-7\">https://doi.org/10.1038/s41467-025-63044-7</a>."},"arxiv":1,"has_accepted_license":"1","year":"2025","date_created":"2025-09-27T13:27:31Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":16,"APC_amount":"7068 EUR","date_updated":"2026-05-20T07:56:59Z","project":[{"_id":"238598C6-32DE-11EA-91FC-C7463DDC885E","grant_number":"662960","name":"Revisiting the Turbulence Problem Using Statistical Mechanics"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"ddc":["532"],"date_published":"2025-09-26T00:00:00Z","abstract":[{"lang":"eng","text":"The recent classification of the onset of turbulence as a directed percolation (DP) phase transition has been applied to all major shear flows including pipe, channel, Couette and boundary layer flows. A cornerstone of the DP analogy is the memoryless (Poisson) property of turbulent sites. We here show that, for the classic case of channel flow, neither the decay nor the proliferation of turbulent stripes is memoryless. As demonstrated by a standard analysis of the respective survival curves, isolated channel stripes, in the immediate vicinity of the critical point, age. Consequently, the one to one mapping between turbulent stripes and active DP-sites is not fulfilled in this low Reynolds number regime. In addition, the interpretation of turbulence as a chaotic saddle with supertransient properties, the basis of recent theoretical progress, does not apply to individual localized stripes. The discrepancy between channel flow and the transition models established for pipe and Couette flow, illustrates that seemingly minor geometrical differences between flows can give rise to instabilities and growth mechanisms that fundamentally alter the nature of the transition to turbulence."}],"doi":"10.1038/s41467-025-63044-7","publication_status":"published","external_id":{"arxiv":["2112.06537"],"isi":["001582555200041"]},"department":[{"_id":"BjHo"}],"file":[{"creator":"gyalniz","file_name":"s41467-025-63044-7.pdf","date_updated":"2025-09-27T13:32:03Z","file_size":2226082,"access_level":"open_access","relation":"main_file","file_id":"20403","checksum":"945926ead9cde464435d456427e2869e","content_type":"application/pdf","date_created":"2025-09-27T13:32:03Z"}],"intvolume":"        16","publication":"Nature Communications","file_date_updated":"2025-09-27T13:32:03Z"},{"date_created":"2025-09-28T22:01:26Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":141,"date_updated":"2026-01-05T13:09:08Z","ddc":["570"],"project":[{"name":"The highjacking of meiosis for asexual reproduction","_id":"34ae1506-11ca-11ed-8bc3-c14f4c474396","grant_number":"F8810"}],"date_published":"2025-11-01T00:00:00Z","doi":"10.1016/j.matbio.2025.09.002","abstract":[{"lang":"eng","text":"Collagens are fundamental components of extracellular matrices, requiring precise intracellular post-translational modifications for proper function. Among the modifications, prolyl 4-hydroxylation is critical to stabilise the collagen triple helix. In humans, this reaction is mediated by collagen prolyl 4-hydroxylases (P4Hs). While humans possess three genes encoding these enzymes (P4H⍺s), Drosophila melanogaster harbour at least 26 candidates for collagen P4H⍺s despite its simple genome, and it is poorly understood which of them are actually working on collagen in the fly. In this study, we addressed this question by carrying out thorough bioinformatic and biochemical analyses. We demonstrate that among the 26 potential collagen P4H⍺s, PH4⍺EFB shares the highest homology with vertebrate collagen P4H⍺s. Furthermore, while collagen P4Hs and their substrates must exist in the same cells, our transcriptomic analyses at the tissue and single cell levels showed a global co-expression of PH4⍺EFB but not the other P4H⍺-related genes with the collagen IV genes. Moreover, expression of PH4⍺EFB during embryogenesis was found to precede that of collagen IV, presumably enabling efficient collagen modification by PH4⍺EFB. Finally, biochemical assays confirm that PH4⍺EFB binds collagen, supporting its direct role in collagen IV modification. Collectively, we identify PH4⍺EFB as the primary and potentially constitutive prolyl 4-hydroxylase responsible for collagen IV biosynthesis in Drosophila. Our findings highlight the remarkably simple nature of Drosophila collagen IV biosynthesis, which may serve as a blueprint for defining the minimal requirements for collagen engineering."}],"external_id":{"pmid":["40946811"],"isi":["001583892100002"]},"department":[{"_id":"BeVi"}],"publication_status":"published","intvolume":"       141","file":[{"content_type":"application/pdf","success":1,"date_created":"2026-01-05T13:09:01Z","relation":"main_file","checksum":"764257db41865d19daec1935788f72d7","file_id":"20948","file_name":"2025_MatrixBiology_Ishikawa.pdf","date_updated":"2026-01-05T13:09:01Z","file_size":5844254,"access_level":"open_access","creator":"dernst"}],"publication":"Matrix Biology","file_date_updated":"2026-01-05T13:09:01Z","publication_identifier":{"eissn":["1569-1802"],"issn":["0945-053X"]},"publisher":"Springer Nature","month":"11","quality_controlled":"1","page":"101-113","status":"public","OA_place":"publisher","type":"journal_article","day":"01","author":[{"first_name":"Yoshihiro","full_name":"Ishikawa, Yoshihiro","last_name":"Ishikawa"},{"id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","last_name":"Toups","full_name":"Toups, Melissa A","orcid":"0000-0002-9752-7380","first_name":"Melissa A"},{"last_name":"Elkrewi","full_name":"Elkrewi, Marwan N","orcid":"0000-0002-5328-7231","id":"0B46FACA-A8E1-11E9-9BD3-79D1E5697425","first_name":"Marwan N"},{"first_name":"Allison L.","last_name":"Zajac","full_name":"Zajac, Allison L."},{"first_name":"Sally","last_name":"Horne-Badovinac","full_name":"Horne-Badovinac, Sally"},{"first_name":"Yutaka","last_name":"Matsubayashi","full_name":"Matsubayashi, Yutaka"}],"language":[{"iso":"eng"}],"oa":1,"issue":"11","_id":"20404","PlanS_conform":"1","article_processing_charge":"Yes (in subscription journal)","article_type":"original","OA_type":"hybrid","isi":1,"oa_version":"Published Version","scopus_import":"1","acknowledgement":"This project was supported by the All May See Foundation 7031,182 to YI, the Louisiana Board of Regents Support Fund: Research Competitiveness Subprogram to MAT, Austrian science fund (FWF) as part of the SFB Meiosis consortium FWF SFB F88-10 to Beatriz Vicoso (supported ME), American Heart Association 16POST2726018 and American Cancer Society 132,123-PF-18–025–01-CSM postdoctoral fellowships to ALZ, National Institutes of Health R01 GM136961 and R35 GM148485 to SH-B, and the Academy of Medical Sciences/the Wellcome Trust/ the Government Department of Business, Energy and Industrial Strategy/the British Heart Foundation/Diabetes UK Springboard Award SBF008\\1115 to YM. \r\nComputational analyses of single-nucleus transcriptome data were performed on the high performance computer (HPC) at Bournemouth University, the HPC at Institute of Science and Technology Austria, and the high-performance computational resources provided by the Louisiana Optical Network Infrastructure (http://www.loni.org). The authors are grateful to the researchers who published the transcriptome datasets [48,49,52,55] that became the essential bases for this study, to FlyBase for curating the datasets in an easily accessible format, and the Drosophila Genomics Resource Center (DGRC), supported by NIH grant 2P40OD010949, for providing the D17 cell line used in this research. The authors thank Kristian Koski (University of Oulu, Finland) for crucial advice on the domain structure of collagen P4H⍺s, and Ryusuke Niwa and Ryo Hoshino (University of Tsukuba, Japan) for helpful discussions on SP.","title":"Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV","has_accepted_license":"1","citation":{"ista":"Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi Y. 2025. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. Matrix Biology. 141(11), 101–113.","apa":"Ishikawa, Y., Toups, M. A., Elkrewi, M. N., Zajac, A. L., Horne-Badovinac, S., &#38; Matsubayashi, Y. (2025). Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. <i>Matrix Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">https://doi.org/10.1016/j.matbio.2025.09.002</a>","short":"Y. Ishikawa, M.A. Toups, M.N. Elkrewi, A.L. Zajac, S. Horne-Badovinac, Y. Matsubayashi, Matrix Biology 141 (2025) 101–113.","ama":"Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi Y. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. <i>Matrix Biology</i>. 2025;141(11):101-113. doi:<a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">10.1016/j.matbio.2025.09.002</a>","ieee":"Y. Ishikawa, M. A. Toups, M. N. Elkrewi, A. L. Zajac, S. Horne-Badovinac, and Y. Matsubayashi, “Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV,” <i>Matrix Biology</i>, vol. 141, no. 11. Springer Nature, pp. 101–113, 2025.","chicago":"Ishikawa, Yoshihiro, Melissa A Toups, Marwan N Elkrewi, Allison L. Zajac, Sally Horne-Badovinac, and Yutaka Matsubayashi. “Evidence for the Major Role of PH4⍺EFB in the Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">https://doi.org/10.1016/j.matbio.2025.09.002</a>.","mla":"Ishikawa, Yoshihiro, et al. “Evidence for the Major Role of PH4⍺EFB in the Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>, vol. 141, no. 11, Springer Nature, 2025, pp. 101–13, doi:<a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">10.1016/j.matbio.2025.09.002</a>."},"pmid":1},{"page":"5220-5230","status":"public","OA_place":"publisher","type":"journal_article","day":"11","publication_identifier":{"eissn":["2330-4022"]},"publisher":"American Chemical Society","quality_controlled":"1","month":"08","_id":"20405","corr_author":"1","issue":"9","PlanS_conform":"1","article_type":"original","article_processing_charge":"Yes (via OA deal)","author":[{"first_name":"Dusan","id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87","last_name":"Lorenc","full_name":"Lorenc, Dusan"},{"id":"37D278BC-F248-11E8-B48F-1D18A9856A87","last_name":"Volosniev","orcid":"0000-0003-0393-5525","full_name":"Volosniev, Artem","first_name":"Artem"},{"full_name":"Zhumekenov, Ayan A.","last_name":"Zhumekenov","first_name":"Ayan A."},{"last_name":"Lee","orcid":"0000-0002-6962-8598","full_name":"Lee, Seungho","id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho"},{"first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bakr, Osman M.","last_name":"Bakr","first_name":"Osman M."},{"first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","last_name":"Lemeshko"},{"first_name":"Zhanybek","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","last_name":"Alpichshev","orcid":"0000-0002-7183-5203","full_name":"Alpichshev, Zhanybek"}],"oa":1,"language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"EM-Fac"}],"title":"Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites","isi":1,"OA_type":"hybrid","scopus_import":"1","oa_version":"Published Version","acknowledgement":"A.G.V. thanks Peter Balling for useful discussions. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Electron Microscopy Facility (EMF), and by the Werner Siemens Foundation (WSS) for financial support.","has_accepted_license":"1","citation":{"short":"D. Lorenc, A. Volosniev, A.A. Zhumekenov, S. Lee, M. Ibáñez, O.M. Bakr, M. Lemeshko, Z. Alpichshev, ACS Photonics 12 (2025) 5220–5230.","ama":"Lorenc D, Volosniev A, Zhumekenov AA, et al. Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. <i>ACS Photonics</i>. 2025;12(9):5220-5230. doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">10.1021/acsphotonics.5c01360</a>","ieee":"D. Lorenc <i>et al.</i>, “Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites,” <i>ACS Photonics</i>, vol. 12, no. 9. American Chemical Society, pp. 5220–5230, 2025.","apa":"Lorenc, D., Volosniev, A., Zhumekenov, A. A., Lee, S., Ibáñez, M., Bakr, O. M., … Alpichshev, Z. (2025). Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. <i>ACS Photonics</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">https://doi.org/10.1021/acsphotonics.5c01360</a>","ista":"Lorenc D, Volosniev A, Zhumekenov AA, Lee S, Ibáñez M, Bakr OM, Lemeshko M, Alpichshev Z. 2025. Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. ACS Photonics. 12(9), 5220–5230.","mla":"Lorenc, Dusan, et al. “Observation of Analogue Dynamic Schwinger Effect and Non-Perturbative Light Sensing in Lead Halide Perovskites.” <i>ACS Photonics</i>, vol. 12, no. 9, American Chemical Society, 2025, pp. 5220–30, doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">10.1021/acsphotonics.5c01360</a>.","chicago":"Lorenc, Dusan, Artem Volosniev, Ayan A. Zhumekenov, Seungho Lee, Maria Ibáñez, Osman M. Bakr, Mikhail Lemeshko, and Zhanybek Alpichshev. “Observation of Analogue Dynamic Schwinger Effect and Non-Perturbative Light Sensing in Lead Halide Perovskites.” <i>ACS Photonics</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">https://doi.org/10.1021/acsphotonics.5c01360</a>."},"arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-09-28T22:01:26Z","year":"2025","ddc":["540","530"],"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"date_published":"2025-08-11T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":12,"date_updated":"2025-12-01T12:59:51Z","external_id":{"arxiv":["2406.05032"],"isi":["001547359300001"]},"department":[{"_id":"MaIb"},{"_id":"MiLe"},{"_id":"ZhAl"}],"publication_status":"published","doi":"10.1021/acsphotonics.5c01360","abstract":[{"text":"Dielectric breakdown of physical vacuum (Schwinger effect) is the textbook demonstration of compatibility of Relativity and Quantum theory. Although observing this effect is still practically unachievable, its analogue generalizations have been shown to be more readily attainable. This paper demonstrates that a gapped Dirac semiconductor, methylammonium lead-bromide perovskite (MAPbBr3), exhibits analogue dynamic Schwinger effect. Tunneling ionization under deep subgap mid-infrared irradiation leads to intense photoluminescence in the visible range, in full agreement with quasi-adiabatic theory. In addition to revealing a gapped extended system suitable for studying the analogue Schwinger effect, this observation holds great potential for nonperturbative field sensing, i.e., sensing electric fields through nonperturbative light-matter interactions. First, this paper illustrates this by measuring the local deviation from the nominally cubic phase of a perovskite single crystal, which can be interpreted in terms of frozen-in fields. Next, it is shown that analogue dynamic Schwinger effect can be used for nonperturbative amplification of nonparametric upconversion process in perovskites driven simultaneously by multiple optical fields. This discovery demonstrates the potential for material response beyond perturbation theory in the tunneling regime, offering extremely sensitive light detection and amplification across an ultrabroad spectral range not accessible by conventional devices.","lang":"eng"}],"file_date_updated":"2025-10-20T11:02:21Z","file":[{"access_level":"open_access","file_name":"2025_ACSPhotonics_Lorenc.pdf","date_updated":"2025-10-20T11:02:21Z","file_size":6609950,"creator":"dernst","date_created":"2025-10-20T11:02:21Z","success":1,"content_type":"application/pdf","file_id":"20502","checksum":"d42476279287a9a2f8aeafaef032f4a7","relation":"main_file"}],"intvolume":"        12","publication":"ACS Photonics"},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":701,"date_updated":"2026-02-16T12:13:12Z","ddc":["520"],"date_published":"2025-09-01T00:00:00Z","date_created":"2025-09-28T22:01:27Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"access_level":"open_access","file_name":"2025_AstronomyAstrophysics_deGraaff2.pdf","date_updated":"2025-09-29T06:59:14Z","file_size":1218479,"creator":"dernst","date_created":"2025-09-29T06:59:14Z","content_type":"application/pdf","success":1,"file_id":"20409","checksum":"cf93d635121dbf4865fd080c517927d0","relation":"main_file"}],"publication":"Astronomy & Astrophysics","intvolume":"       701","file_date_updated":"2025-09-29T06:59:14Z","doi":"10.1051/0004-6361/202554681","abstract":[{"text":"The origin of the rest-optical emission of compact, red, high-redshift sources known as little red dots (LRDs) poses a major puzzle. If interpreted as starlight, it would imply that LRDs constitute the densest stellar systems in the Universe. However, alternative models suggest active galactic nuclei (AGN) may instead power the rest-optical continuum. Here, we present JWST/NIRSpec, NIRCam, and MIRI observations from the RUBIES and PRIMER programs of The Cliff: a bright LRD at z = 3.55 with an exceptional Balmer break, twice as strong as that of any high-redshift source previously observed. The spectra also reveal broad hydrogen (Hα FWHM ∼ 1500 km s−1) and He I emission, but no significant metal lines. We demonstrate that massive evolved stellar populations cannot explain the observed spectrum, even when considering unusually steep and strong dust attenuation or reasonable variations in the initial mass function. Moreover, the formally best-fit stellar mass and compact size (M* ∼ 1010.5 M⊙,  re ∼ 40 pc) would imply densities at which near-monthly stellar collisions might lead to significant X-ray emission. We argue that the Balmer break, emission lines, and Hα absorption line are instead most plausibly explained by a black hole star (BH*) scenario, in which dense gas surrounds a powerful ionising source. In contrast to recently proposed BH* models of dust-reddened AGN, we show that spectral fits in the rest UV to near-infrared favour an intrinsically redder continuum over strong dust reddening. This may point to a super-Eddington accreting massive black hole or, possibly, the presence of (super)massive stars in a nuclear star cluster. The Cliff is the clearest evidence to date that at least some LRDs are not ultra-dense massive galaxies, and are instead powered by a central ionising source embedded in dense, absorbing gas.","lang":"eng"}],"external_id":{"isi":["001570450900004"],"arxiv":["2503.16600"]},"department":[{"_id":"JoMa"}],"publication_status":"published","author":[{"first_name":"Anna","full_name":"De Graaff, Anna","last_name":"De Graaff"},{"last_name":"Rix","full_name":"Rix, Hans Walter","first_name":"Hans Walter"},{"first_name":"Rohan P.","full_name":"Naidu, Rohan P.","last_name":"Naidu"},{"first_name":"Ivo","full_name":"Labbé, Ivo","last_name":"Labbé"},{"first_name":"Bingjie","full_name":"Wang, Bingjie","last_name":"Wang"},{"first_name":"Joel","last_name":"Leja","full_name":"Leja, Joel"},{"last_name":"Matthee","orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J"},{"full_name":"Katz, Harley","last_name":"Katz","first_name":"Harley"},{"last_name":"Greene","full_name":"Greene, Jenny E.","first_name":"Jenny E."},{"first_name":"Raphael E.","full_name":"Hviding, Raphael E.","last_name":"Hviding"},{"full_name":"Baggen, Josephine","last_name":"Baggen","first_name":"Josephine"},{"first_name":"Rachel","full_name":"Bezanson, Rachel","last_name":"Bezanson"},{"first_name":"Leindert A.","full_name":"Boogaard, Leindert A.","last_name":"Boogaard"},{"first_name":"Gabriel","full_name":"Brammer, Gabriel","last_name":"Brammer"},{"last_name":"Dayal","full_name":"Dayal, Pratika","first_name":"Pratika"},{"full_name":"Van Dokkum, Pieter","last_name":"Van Dokkum","first_name":"Pieter"},{"first_name":"Andy D.","last_name":"Goulding","full_name":"Goulding, Andy D."},{"first_name":"Michaela","full_name":"Hirschmann, Michaela","last_name":"Hirschmann"},{"first_name":"Michael V.","full_name":"Maseda, Michael V.","last_name":"Maseda"},{"last_name":"Mcconachie","full_name":"Mcconachie, Ian","first_name":"Ian"},{"first_name":"Tim B.","full_name":"Miller, Tim B.","last_name":"Miller"},{"first_name":"Erica","full_name":"Nelson, Erica","last_name":"Nelson"},{"full_name":"Oesch, Pascal A.","last_name":"Oesch","first_name":"Pascal A."},{"last_name":"Setton","full_name":"Setton, David J.","first_name":"David J."},{"last_name":"Shivaei","full_name":"Shivaei, Irene","first_name":"Irene"},{"last_name":"Weibel","full_name":"Weibel, Andrea","first_name":"Andrea"},{"first_name":"Katherine E.","last_name":"Whitaker","full_name":"Whitaker, Katherine E."},{"last_name":"Williams","full_name":"Williams, Christina C.","first_name":"Christina C."}],"oa":1,"language":[{"iso":"eng"}],"_id":"20406","PlanS_conform":"1","article_type":"original","article_processing_charge":"No","article_number":"A168","publisher":"EDP Sciences","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"quality_controlled":"1","month":"09","status":"public","OA_place":"publisher","type":"journal_article","day":"01","has_accepted_license":"1","citation":{"ista":"De Graaff A, Rix HW, Naidu RP, Labbé I, Wang B, Leja J, Matthee JJ, Katz H, Greene JE, Hviding RE, Baggen J, Bezanson R, Boogaard LA, Brammer G, Dayal P, Van Dokkum P, Goulding AD, Hirschmann M, Maseda MV, Mcconachie I, Miller TB, Nelson E, Oesch PA, Setton DJ, Shivaei I, Weibel A, Whitaker KE, Williams CC. 2025. A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. Astronomy &#38; Astrophysics. 701, A168.","apa":"De Graaff, A., Rix, H. W., Naidu, R. P., Labbé, I., Wang, B., Leja, J., … Williams, C. C. (2025). A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202554681\">https://doi.org/10.1051/0004-6361/202554681</a>","ieee":"A. De Graaff <i>et al.</i>, “A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.","short":"A. De Graaff, H.W. Rix, R.P. Naidu, I. Labbé, B. Wang, J. Leja, J.J. Matthee, H. Katz, J.E. Greene, R.E. Hviding, J. Baggen, R. Bezanson, L.A. Boogaard, G. Brammer, P. Dayal, P. Van Dokkum, A.D. Goulding, M. Hirschmann, M.V. Maseda, I. Mcconachie, T.B. Miller, E. Nelson, P.A. Oesch, D.J. Setton, I. Shivaei, A. Weibel, K.E. Whitaker, C.C. Williams, Astronomy &#38; Astrophysics 701 (2025).","ama":"De Graaff A, Rix HW, Naidu RP, et al. A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. <i>Astronomy &#38; Astrophysics</i>. 2025;701. doi:<a href=\"https://doi.org/10.1051/0004-6361/202554681\">10.1051/0004-6361/202554681</a>","chicago":"De Graaff, Anna, Hans Walter Rix, Rohan P. Naidu, Ivo Labbé, Bingjie Wang, Joel Leja, Jorryt J Matthee, et al. “A Remarkable Ruby: Absorption in Dense Gas, Rather than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot at z = 3.5.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202554681\">https://doi.org/10.1051/0004-6361/202554681</a>.","mla":"De Graaff, Anna, et al. “A Remarkable Ruby: Absorption in Dense Gas, Rather than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot at z = 3.5.” <i>Astronomy &#38; Astrophysics</i>, vol. 701, A168, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202554681\">10.1051/0004-6361/202554681</a>."},"arxiv":1,"isi":1,"OA_type":"diamond","oa_version":"Published Version","scopus_import":"1","acknowledgement":"We thank the PRIMER team for making their imaging data publicly available immediately. We thank Jaime Villaseñor and Friedrich Röpke for helpful discussions. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs #1837 and #4233. Support for program #4233 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. REH acknowledges support by the German Aerospace Center (DLR) and the Federal Ministry for Economic Affairs and Energy (BMWi) through program 50OR2403 ‘RUBIES’. This research was supported by the International Space Science Institute (ISSI) in Bern, through ISSI International Team project #562. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. Support for this work for RPN was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. TBM was supported by a CIERA fellowship. Open Access funding provided by Max Planck Society.","title":"A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5"},{"month":"09","quality_controlled":"1","publication_identifier":{"eissn":["1615-3383"],"issn":["1615-3375"]},"publisher":"Springer Nature","day":"15","type":"journal_article","OA_place":"publisher","status":"public","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Ennes","full_name":"Ennes, Henrique","first_name":"Henrique"},{"id":"40ebcc9d-905f-11ef-bf0a-dc475da8a04e","last_name":"Tinarrage","orcid":"0000-0002-1404-1095","full_name":"Tinarrage, Raphaël","first_name":"Raphaël"}],"article_processing_charge":"Yes (via OA deal)","article_type":"original","PlanS_conform":"1","_id":"20407","corr_author":"1","acknowledgement":"The original work behind this article was developed for HE’s master’s thesis, supervised by RT. We are mostly in debt to César Camacho, who was HE’s co-advisor, as well as the members of the thesis jury, Clément Maria, Eduardo Mendes, and Jameson Cahill, not only for agreeing to evaluate the original work but also for many valuable inputs. Finally, we are indebted to the anonymous reviewers for their important feedback and suggestions. Open access funding provided by Institute of Science and Technology (IST Austria).","oa_version":"Published Version","scopus_import":"1","isi":1,"OA_type":"hybrid","title":"LieDetect: Detection of representation orbits of compact Lie groups from point clouds","arxiv":1,"citation":{"apa":"Ennes, H., &#38; Tinarrage, R. (2025). LieDetect: Detection of representation orbits of compact Lie groups from point clouds. <i>Foundations of Computational Mathematics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10208-025-09728-4\">https://doi.org/10.1007/s10208-025-09728-4</a>","ista":"Ennes H, Tinarrage R. 2025. LieDetect: Detection of representation orbits of compact Lie groups from point clouds. Foundations of Computational Mathematics.","ama":"Ennes H, Tinarrage R. LieDetect: Detection of representation orbits of compact Lie groups from point clouds. <i>Foundations of Computational Mathematics</i>. 2025. doi:<a href=\"https://doi.org/10.1007/s10208-025-09728-4\">10.1007/s10208-025-09728-4</a>","ieee":"H. Ennes and R. Tinarrage, “LieDetect: Detection of representation orbits of compact Lie groups from point clouds,” <i>Foundations of Computational Mathematics</i>. Springer Nature, 2025.","short":"H. Ennes, R. Tinarrage, Foundations of Computational Mathematics (2025).","chicago":"Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational Mathematics</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10208-025-09728-4\">https://doi.org/10.1007/s10208-025-09728-4</a>.","mla":"Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational Mathematics</i>, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s10208-025-09728-4\">10.1007/s10208-025-09728-4</a>."},"year":"2025","date_created":"2025-09-28T22:01:27Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s10208-025-09728-4"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-06-18T18:22:42Z","date_published":"2025-09-15T00:00:00Z","ddc":["500"],"abstract":[{"text":"We suggest a new algorithm to estimate representations of compact Lie groups from finite samples of their orbits. Different from other reported techniques, our method allows the retrieval of the precise representation type as a direct sum of irreducible representations. Moreover, the knowledge of the representation type permits the reconstruction of its orbit, which is useful for identifying the Lie group that generates the action, from a finite list of candidates. Our algorithm is general for any compact Lie group, but only instantiations for SO(2), T^d, SU(2), and SO(3) are considered. Theoretical guarantees of robustness in terms of Hausdorff and Wasserstein distances are derived. Our tools are drawn from geometric measure theory, computational geometry, and optimization on matrix manifolds. The algorithm is tested for synthetic data up to dimension 32, as well as real-life applications in image analysis, harmonic analysis, density estimation, equivariant neural networks, chemical conformational spaces, and classical mechanics systems, achieving very accurate results.","lang":"eng"}],"doi":"10.1007/s10208-025-09728-4","publication_status":"epub_ahead","department":[{"_id":"UlWa"}],"external_id":{"arxiv":["2309.03086"],"isi":["001571197200001"]},"publication":"Foundations of Computational Mathematics"},{"file_date_updated":"2025-10-07T08:57:14Z","file":[{"file_id":"20420","checksum":"fa6d5946feb37b678ee1c6dffb4fa167","relation":"source_file","date_created":"2025-10-03T12:29:43Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","creator":"slee","access_level":"closed","file_size":88706648,"date_updated":"2025-10-07T08:57:14Z","file_name":"2025_Lee_Seungho_Thesis.docx"},{"content_type":"application/pdf","date_created":"2025-10-03T12:29:25Z","relation":"main_file","checksum":"c5ba6d464113ad0c5812a9d24b539b86","file_id":"20421","embargo":"2026-10-03","date_updated":"2025-10-03T12:29:25Z","file_name":"2025_Lee_Seungho_Thesis__.pdf","file_size":14587276,"access_level":"closed","embargo_to":"open_access","creator":"slee"}],"publication_status":"published","department":[{"_id":"GradSch"},{"_id":"MaIb"}],"doi":"10.15479/AT-ISTA-20415","degree_awarded":"PhD","alternative_title":["ISTA Thesis"],"date_published":"2025-10-01T00:00:00Z","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"ddc":["540"],"date_updated":"2026-04-07T11:52:32Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2025","date_created":"2025-10-01T09:04:00Z","citation":{"short":"S. Lee, Nanoparticle-Based Precursors toward Advanced Crystalline Inorganic Solids, Institute of Science and Technology Austria, 2025.","ieee":"S. Lee, “Nanoparticle-based precursors toward advanced crystalline inorganic solids,” Institute of Science and Technology Austria, 2025.","ama":"Lee S. Nanoparticle-based precursors toward advanced crystalline inorganic solids. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20415\">10.15479/AT-ISTA-20415</a>","apa":"Lee, S. (2025). <i>Nanoparticle-based precursors toward advanced crystalline inorganic solids</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20415\">https://doi.org/10.15479/AT-ISTA-20415</a>","ista":"Lee S. 2025. Nanoparticle-based precursors toward advanced crystalline inorganic solids. Institute of Science and Technology Austria.","mla":"Lee, Seungho. <i>Nanoparticle-Based Precursors toward Advanced Crystalline Inorganic Solids</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20415\">10.15479/AT-ISTA-20415</a>.","chicago":"Lee, Seungho. “Nanoparticle-Based Precursors toward Advanced Crystalline Inorganic Solids.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20415\">https://doi.org/10.15479/AT-ISTA-20415</a>."},"has_accepted_license":"1","related_material":{"record":[{"id":"15357","relation":"part_of_dissertation","status":"public"},{"id":"12237","relation":"part_of_dissertation","status":"public"}]},"title":"Nanoparticle-based precursors toward advanced crystalline inorganic solids","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"EM-Fac"}],"oa_version":"Published Version","article_processing_charge":"No","corr_author":"1","_id":"20415","language":[{"iso":"eng"}],"supervisor":[{"first_name":"Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Protesescu","full_name":"Protesescu, Loredana","first_name":"Loredana"},{"first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander"}],"author":[{"first_name":"Seungho","last_name":"Lee","orcid":"0000-0002-6962-8598","full_name":"Lee, Seungho","id":"BB243B88-D767-11E9-B658-BC13E6697425"}],"day":"01","type":"dissertation","OA_place":"publisher","status":"public","page":"144","month":"10","publication_identifier":{"issn":["2663-337X"]},"publisher":"Institute of Science and Technology Austria"},{"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"volume":16,"date_updated":"2026-05-20T08:52:01Z","APC_amount":"7068 EUR","ddc":["570"],"project":[{"name":"Biomechanics of stem cell fate determination","grant_number":"ALTF 522-2021","_id":"628f3fb1-2b32-11ec-9570-83ce778803f7"},{"_id":"05943252-7A3F-11EA-A408-12923DDC885E","grant_number":"851288","call_identifier":"H2020","name":"Design Principles of Branching Morphogenesis"}],"date_published":"2025-09-26T00:00:00Z","year":"2025","date_created":"2025-10-05T22:01:34Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"        16","file":[{"creator":"dernst","access_level":"open_access","file_name":"2025_NatureComm_Sahu.pdf","file_size":2816813,"date_updated":"2025-10-13T12:37:04Z","file_id":"20464","checksum":"d1656576883b23902545328e2d640234","relation":"main_file","date_created":"2025-10-13T12:37:04Z","content_type":"application/pdf","success":1}],"publication":"Nature Communications","file_date_updated":"2025-10-13T12:37:04Z","ec_funded":1,"abstract":[{"lang":"eng","text":"Homeostasis relies on a precise balance of fate choices between renewal and differentiation. Although progress has been done to characterize the dynamics of single-cell fate choices, their underlying mechanistic basis often remains unclear. Concentrating on skin epidermis as a paradigm for multilayered tissues with complex fate choices, we develop a 3D vertex-based model with proliferation in the basal layer, showing that mechanical competition for space naturally gives rise to homeostasis and neutral drift dynamics that are seen experimentally. We then explore the effect of introducing mechanical heterogeneities between cellular subpopulations. We uncover that relatively small tension heterogeneities, reflected by distinct morphological changes in single-cell shapes, can be sufficient to heavily tilt cellular dynamics towards exponential growth. We thus derive a master relationship between cell shape and long-term clonal dynamics, which we validated during basal cell carcinoma initiation in mouse epidermis. Altogether, we propose a theoretical framework to link mechanical forces, quantitative cellular morphologies and cellular fate outcomes in complex tissues."}],"doi":"10.1038/s41467-025-62882-9","publication_status":"published","external_id":{"isi":["001582555200011"],"pmid":["41006218"]},"department":[{"_id":"EdHa"}],"oa":1,"language":[{"iso":"eng"}],"author":[{"first_name":"Preeti","id":"55BA52EE-A185-11EA-88FD-18AD3DDC885E","last_name":"Sahu","full_name":"Sahu, Preeti"},{"first_name":"Sara","last_name":"Monteiro-Ferreira","full_name":"Monteiro-Ferreira, Sara"},{"first_name":"Sara","full_name":"Canato, Sara","last_name":"Canato"},{"full_name":"Soares, Raquel Maia","last_name":"Soares","first_name":"Raquel Maia"},{"first_name":"Adriana","full_name":"Sánchez-Danés, Adriana","last_name":"Sánchez-Danés"},{"first_name":"Edouard B","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87"}],"article_type":"original","article_processing_charge":"Yes","_id":"20424","corr_author":"1","DOAJ_listed":"1","quality_controlled":"1","month":"09","publication_identifier":{"eissn":["2041-1723"]},"article_number":"8440","publisher":"Springer Nature","type":"journal_article","day":"26","status":"public","OA_place":"publisher","citation":{"ama":"Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo EB. Mechanical control of cell fate decisions in the skin epidermis. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-62882-9\">10.1038/s41467-025-62882-9</a>","short":"P. Sahu, S. Monteiro-Ferreira, S. Canato, R.M. Soares, A. Sánchez-Danés, E.B. Hannezo, Nature Communications 16 (2025).","ieee":"P. Sahu, S. Monteiro-Ferreira, S. Canato, R. M. Soares, A. Sánchez-Danés, and E. B. Hannezo, “Mechanical control of cell fate decisions in the skin epidermis,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","ista":"Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo EB. 2025. Mechanical control of cell fate decisions in the skin epidermis. Nature Communications. 16, 8440.","apa":"Sahu, P., Monteiro-Ferreira, S., Canato, S., Soares, R. M., Sánchez-Danés, A., &#38; Hannezo, E. B. (2025). Mechanical control of cell fate decisions in the skin epidermis. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-62882-9\">https://doi.org/10.1038/s41467-025-62882-9</a>","chicago":"Sahu, Preeti, Sara Monteiro-Ferreira, Sara Canato, Raquel Maia Soares, Adriana Sánchez-Danés, and Edouard B Hannezo. “Mechanical Control of Cell Fate Decisions in the Skin Epidermis.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-62882-9\">https://doi.org/10.1038/s41467-025-62882-9</a>.","mla":"Sahu, Preeti, et al. “Mechanical Control of Cell Fate Decisions in the Skin Epidermis.” <i>Nature Communications</i>, vol. 16, 8440, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-62882-9\">10.1038/s41467-025-62882-9</a>."},"has_accepted_license":"1","pmid":1,"acknowledgement":"We thank Alois Schlögl, Paula Sanematsu, Susana Moreno Flores, Bernat Corominas-Murtra, Stefania Tavano, Gayathri Singharaju, and Hannezo group members for helpful discussions, the Bioimaging facility at ISTA, as well as Matthias Merkel and Lisa Manning for sharing the 3D Voronoi code. We also thank the Champalimaud animal facility, Anna Pezzarossa and the Champalimaud ABBE platform for the help with microscopy and image processing. This work was supported by EMBO (ALTF 522-2021), a Fundação para a Ciência e Tecnologia grant to A.S.D. (PTDC/MED-ONC/5553/2020), as well as the European Research Council (grant 851288 to EH). A.S.D., S.C., and R.M.S. are supported by QuantOCancer Project Horizon European Union’s Horizon 2020 program (grant agreement No 810653).","oa_version":"Published Version","scopus_import":"1","OA_type":"gold","isi":1,"title":"Mechanical control of cell fate decisions in the skin epidermis","acknowledged_ssus":[{"_id":"Bio"}]},{"title":"The light echo of a high-redshift quasar mapped with Lyα tomography","OA_type":"gold","isi":1,"acknowledgement":"This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs #1243 and #4713.\r\n\r\nAll of the data presented in this Letter were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations analyzed can be accessed via doi:10.17909/w7hm-qb39.\r\nJ.M. is supported by the European Union (ERC, AGENTS, 101076224).","scopus_import":"1","oa_version":"Published Version","has_accepted_license":"1","arxiv":1,"citation":{"chicago":"Eilers, Anna Christina, Minghao Yue, Jorryt J Matthee, Joseph F. Hennawi, Frederick B. Davies, Robert A. Simcoe, Richard Teague, et al. “The Light Echo of a High-Redshift Quasar Mapped with Lyα Tomography.” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/2041-8213/ae057a\">https://doi.org/10.3847/2041-8213/ae057a</a>.","mla":"Eilers, Anna Christina, et al. “The Light Echo of a High-Redshift Quasar Mapped with Lyα Tomography.” <i>The Astrophysical Journal Letters</i>, vol. 991, no. 2, L40, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae057a\">10.3847/2041-8213/ae057a</a>.","ama":"Eilers AC, Yue M, Matthee JJ, et al. The light echo of a high-redshift quasar mapped with Lyα tomography. <i>The Astrophysical Journal Letters</i>. 2025;991(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae057a\">10.3847/2041-8213/ae057a</a>","ieee":"A. C. Eilers <i>et al.</i>, “The light echo of a high-redshift quasar mapped with Lyα tomography,” <i>The Astrophysical Journal Letters</i>, vol. 991, no. 2. IOP Publishing, 2025.","short":"A.C. Eilers, M. Yue, J.J. Matthee, J.F. Hennawi, F.B. Davies, R.A. Simcoe, R. Teague, R. Bordoloi, G. Brammer, Y. Kang, D. Kashino, R. Mackenzie, R.P. Naidu, B. Navarrete, The Astrophysical Journal Letters 991 (2025).","ista":"Eilers AC, Yue M, Matthee JJ, Hennawi JF, Davies FB, Simcoe RA, Teague R, Bordoloi R, Brammer G, Kang Y, Kashino D, Mackenzie R, Naidu RP, Navarrete B. 2025. The light echo of a high-redshift quasar mapped with Lyα tomography. The Astrophysical Journal Letters. 991(2), L40.","apa":"Eilers, A. C., Yue, M., Matthee, J. J., Hennawi, J. F., Davies, F. B., Simcoe, R. A., … Navarrete, B. (2025). The light echo of a high-redshift quasar mapped with Lyα tomography. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae057a\">https://doi.org/10.3847/2041-8213/ae057a</a>"},"OA_place":"publisher","status":"public","day":"25","type":"journal_article","publication_identifier":{"issn":["2041-8205"],"eissn":["2041-8213"]},"publisher":"IOP Publishing","article_number":"L40","month":"09","quality_controlled":"1","PlanS_conform":"1","issue":"2","_id":"20425","DOAJ_listed":"1","article_type":"original","article_processing_charge":"Yes","author":[{"last_name":"Eilers","full_name":"Eilers, Anna Christina","first_name":"Anna Christina"},{"last_name":"Yue","full_name":"Yue, Minghao","first_name":"Minghao"},{"first_name":"Jorryt J","orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720"},{"first_name":"Joseph F.","full_name":"Hennawi, Joseph F.","last_name":"Hennawi"},{"full_name":"Davies, Frederick B.","last_name":"Davies","first_name":"Frederick B."},{"last_name":"Simcoe","full_name":"Simcoe, Robert A.","first_name":"Robert A."},{"last_name":"Teague","full_name":"Teague, Richard","first_name":"Richard"},{"last_name":"Bordoloi","full_name":"Bordoloi, Rongmon","first_name":"Rongmon"},{"last_name":"Brammer","full_name":"Brammer, Gabriel","first_name":"Gabriel"},{"last_name":"Kang","full_name":"Kang, Yi","first_name":"Yi"},{"full_name":"Kashino, Daichi","last_name":"Kashino","first_name":"Daichi"},{"last_name":"Mackenzie","full_name":"Mackenzie, Ruari","first_name":"Ruari"},{"first_name":"Rohan P.","last_name":"Naidu","full_name":"Naidu, Rohan P."},{"first_name":"Benjamín","full_name":"Navarrete, Benjamín","last_name":"Navarrete","id":"aa14a535-50c9-11ef-b52e-e0c373d10148"}],"language":[{"iso":"eng"}],"oa":1,"department":[{"_id":"JoMa"},{"_id":"GradSch"}],"external_id":{"isi":["001581023000001"],"arxiv":["2509.05417"]},"publication_status":"published","doi":"10.3847/2041-8213/ae057a","abstract":[{"lang":"eng","text":"Ultraviolet (UV) radiation from accreting black holes ionizes the intergalactic gas around early quasars, carving out highly ionized bubbles in their surroundings. Any changes in a quasar’s luminosity are therefore predicted to produce outward-propagating ionization gradients, affecting the Lyα absorption opacity near the quasar’s systemic redshift. This “proximity effect” is well-documented in rest-UV quasar spectra but only provides a one-dimensional probe along our line of sight. Here we present deep spectroscopic observations with the James Webb Space Telescope (JWST) of galaxies in the background of a superluminous quasar at zQSO ≈ 6.3, which reveal the quasar’s “light echo” with Lyα tomography in the transverse direction. This transverse proximity effect is detected for the first time toward multiple galaxy sightlines, allowing us to map the extent and geometry of the quasar’s ionization cone. We obtain constraints on the orientation and inclination of the cone, as well as an upper limit on the obscured solid angle fraction of fobsc < 91%. Additionally, we find a timescale of the quasar’s UV radiation of tqso = 10^5.6+0.1-0.3 yr, which is significantly shorter than would be required to build up the central supermassive black hole (SMBH) with conventional growth models, but is consistent with independent measurements of the quasars’ duty cycle. Our inferred obscured fraction disfavors a scenario where short quasar lifetimes can be explained exclusively by geometric obscuration, and instead supports the idea that radiatively inefficient accretion or growth in initially heavily enshrouded cocoons plays a pivotal role in early SMBH growth. Our results pave the way for novel studies of quasars’ ionizing geometries and radiative histories at early cosmic times."}],"file_date_updated":"2025-10-13T09:25:12Z","intvolume":"       991","file":[{"creator":"dernst","file_size":23585591,"date_updated":"2025-10-13T09:25:12Z","file_name":"2025_AstrophysicalJour_Eilers.pdf","access_level":"open_access","relation":"main_file","checksum":"3cb8099b9a915755164e5675b33f8a03","file_id":"20461","content_type":"application/pdf","success":1,"date_created":"2025-10-13T09:25:12Z"}],"publication":"The Astrophysical Journal Letters","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-10-05T22:01:35Z","year":"2025","date_published":"2025-09-25T00:00:00Z","project":[{"grant_number":"101076224","_id":"bd9b2118-d553-11ed-ba76-db24564edfea","name":"Young galaxies as tracers and agents of cosmic reionization"}],"ddc":["520"],"date_updated":"2026-02-16T12:44:42Z","volume":991,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2025","date_created":"2025-10-05T22:01:35Z","date_published":"2025-09-30T00:00:00Z","date_updated":"2025-12-01T12:50:24Z","volume":19,"publication_status":"published","department":[{"_id":"MaIb"}],"external_id":{"pmid":["40974325"],"isi":["001575398100001"]},"abstract":[{"text":"SnTe has attracted significant research interest as a lead-free alternative to PbTe; however, its intrinsically high hole concentration results in an undesirably low Seebeck coefficient and elevated electronic thermal conductivity, thus significantly limiting its thermoelectric (TE) performance. Herein, we present a cost-effective, binary thiol-amine-mediated colloidal synthesis method to synthesize Bi-doped SnTe nanoparticles, eliminating the use of tri-n-octylphosphine-based precursors. The introduction of an electron-rich Bi dopant reduces the hole concentration and increases the Seebeck coefficient. Furthermore, post-synthetic surface treatment with chalcogenidocadmate complexes promotes atomic interdiffusion during annealing and consolidation, leading to compositional redistribution and modulation of the electronic band structure. Density functional theory (DFT) calculations reveal that co-modification via Bi doping and CdSe-derived chalcogen incorporation reduces the energy offset at the valence band maxima from 0.30 eV to 0.10 eV, thereby enhancing valence band degeneracy. The synergistic structural and electronic band structure modulations produce an SnTe-based material with a record high power factor of 2.1 mW m–1 K–2 at 900 K, a maximum TE figure of merit (zT) of 1.2, and a promising theoretical conversion efficiency of 8.3%. This study reports a versatile and scalable colloidal synthesis strategy that integrates hierarchical structural modulation with electronic band engineering, offering a synergistic route to significantly enhance the TE performance.","lang":"eng"}],"doi":"10.1021/acsnano.5c12627","intvolume":"        19","publication":"ACS Nano","day":"30","type":"journal_article","page":"34395-34407","status":"public","quality_controlled":"1","month":"09","publisher":"American Chemical Society","publication_identifier":{"eissn":["1936-086X"],"issn":["1936-0851"]},"article_processing_charge":"No","article_type":"original","issue":"38","_id":"20426","language":[{"iso":"eng"}],"author":[{"full_name":"Meng, Weite","last_name":"Meng","first_name":"Weite"},{"first_name":"Lixiang","last_name":"Xu","full_name":"Xu, Lixiang"},{"full_name":"Lu, Shaoqing","last_name":"Lu","first_name":"Shaoqing"},{"full_name":"Li, Mingquan","last_name":"Li","first_name":"Mingquan"},{"first_name":"Mengyao","full_name":"Li, Mengyao","last_name":"Li"},{"first_name":"Yu","full_name":"Zhang, Yu","last_name":"Zhang"},{"first_name":"Qingyue","full_name":"Wang, Qingyue","last_name":"Wang"},{"full_name":"Wang, Wen Jun","last_name":"Wang","first_name":"Wen Jun"},{"last_name":"Huo","full_name":"Huo, Siqi","first_name":"Siqi"},{"full_name":"Bañares, Miguel A.","last_name":"Bañares","first_name":"Miguel A."},{"last_name":"Martin-Gonzalez","full_name":"Martin-Gonzalez, Marisol","first_name":"Marisol"},{"first_name":"Maria","last_name":"Ibáñez","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"},{"last_name":"Hong","full_name":"Hong, Min","first_name":"Min"},{"last_name":"Liu","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu"},{"last_name":"Lim","full_name":"Lim, Khak Ho","first_name":"Khak Ho"}],"title":"Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance","acknowledgement":"Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (Grant No. 22209034), the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province (Grant No. 2022LCX002), and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). K.H.L. acknowledges financial support from the National Natural Science Foundation of China (NSFC) (Grant No. 22208293) and the National Foreign Expert Project (Y20240175). Y.Z. acknowledges funding from the NSFC (Grant No. 52502313) and Wenzhou Basic Scientific Research Project (Grant No. G20240034). Q.W. acknowledges the financial support from the NSFC (Grant No. 22208292) and the “Pioneer” and “Leading Goose” R&D Program of Zhejiang (2025C04021). K.H.L. and Q.W. also acknowledge the Research Funds of the Institute of Zhejiang University-Quzhou (Nos. IZQ2022RCZX101, IZQ2021RCZX003, and IZQ2021RCZX002). M.H. acknowledges the funding from the Australian Research Council and the iLAuNCH Trailblazer, Department of Education, Australia. M.H. acknowledges the computational support from the National Computational Infrastructure (NCI), Australia and Pawsey Supercomputing Centre, Australia. The author also thanks Dr. Lijian Huang and Mr. Mincheng Yu at the Institute of Zhejiang University for the swift technical assistance during XPS characterization and quantification.","scopus_import":"1","oa_version":"None","isi":1,"OA_type":"closed access","pmid":1,"citation":{"short":"W. Meng, L. Xu, S. Lu, M. Li, M. Li, Y. Zhang, Q. Wang, W.J. Wang, S. Huo, M.A. Bañares, M. Martin-Gonzalez, M. Ibáñez, A. Cabot, M. Hong, Y. Liu, K.H. Lim, ACS Nano 19 (2025) 34395–34407.","ieee":"W. Meng <i>et al.</i>, “Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance,” <i>ACS Nano</i>, vol. 19, no. 38. American Chemical Society, pp. 34395–34407, 2025.","ama":"Meng W, Xu L, Lu S, et al. Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. <i>ACS Nano</i>. 2025;19(38):34395-34407. doi:<a href=\"https://doi.org/10.1021/acsnano.5c12627\">10.1021/acsnano.5c12627</a>","ista":"Meng W, Xu L, Lu S, Li M, Li M, Zhang Y, Wang Q, Wang WJ, Huo S, Bañares MA, Martin-Gonzalez M, Ibáñez M, Cabot A, Hong M, Liu Y, Lim KH. 2025. Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. ACS Nano. 19(38), 34395–34407.","apa":"Meng, W., Xu, L., Lu, S., Li, M., Li, M., Zhang, Y., … Lim, K. H. (2025). Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.5c12627\">https://doi.org/10.1021/acsnano.5c12627</a>","chicago":"Meng, Weite, Lixiang Xu, Shaoqing Lu, Mingquan Li, Mengyao Li, Yu Zhang, Qingyue Wang, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsnano.5c12627\">https://doi.org/10.1021/acsnano.5c12627</a>.","mla":"Meng, Weite, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>, vol. 19, no. 38, American Chemical Society, 2025, pp. 34395–407, doi:<a href=\"https://doi.org/10.1021/acsnano.5c12627\">10.1021/acsnano.5c12627</a>."}},{"publication":"Current Biology","intvolume":"        35","publication_status":"published","department":[{"_id":"MiSi"}],"external_id":{"isi":["001592664700001"],"pmid":["40987270"]},"abstract":[{"lang":"eng","text":"Animal cells migrating up chemotactic gradients often show speed oscillations. A new study describes a molecular circuit that switches zebrafish germ cells between phases of straight runs, tumbling and directional reorientation."}],"doi":"10.1016/j.cub.2025.08.016","date_published":"2025-09-22T00:00:00Z","date_updated":"2025-12-01T12:54:02Z","volume":35,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2025","date_created":"2025-10-05T22:01:35Z","pmid":1,"citation":{"short":"Z. LI, M.K. Sixt, Current Biology 35 (2025) R890–R892.","ama":"LI Z, Sixt MK. Cell migration: How animal cells run and tumble. <i>Current Biology</i>. 2025;35(18):R890-R892. doi:<a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">10.1016/j.cub.2025.08.016</a>","ieee":"Z. LI and M. K. Sixt, “Cell migration: How animal cells run and tumble,” <i>Current Biology</i>, vol. 35, no. 18. Elsevier, pp. R890–R892, 2025.","apa":"LI, Z., &#38; Sixt, M. K. (2025). Cell migration: How animal cells run and tumble. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">https://doi.org/10.1016/j.cub.2025.08.016</a>","ista":"LI Z, Sixt MK. 2025. Cell migration: How animal cells run and tumble. Current Biology. 35(18), R890–R892.","mla":"LI, ZIQIANG, and Michael K. Sixt. “Cell Migration: How Animal Cells Run and Tumble.” <i>Current Biology</i>, vol. 35, no. 18, Elsevier, 2025, pp. R890–92, doi:<a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">10.1016/j.cub.2025.08.016</a>.","chicago":"LI, ZIQIANG, and Michael K Sixt. “Cell Migration: How Animal Cells Run and Tumble.” <i>Current Biology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">https://doi.org/10.1016/j.cub.2025.08.016</a>."},"title":"Cell migration: How animal cells run and tumble","oa_version":"None","scopus_import":"1","isi":1,"OA_type":"closed access","article_type":"letter_note","article_processing_charge":"No","corr_author":"1","_id":"20427","issue":"18","language":[{"iso":"eng"}],"author":[{"id":"922e68bb-1727-11ee-857c-966e8cc1b6c3","full_name":"Li, Ziqiang","last_name":"Li","first_name":"Ziqiang"},{"first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","last_name":"Sixt"}],"day":"22","type":"journal_article","status":"public","page":"R890-R892","month":"09","quality_controlled":"1","publication_identifier":{"eissn":["1879-0445"]},"publisher":"Elsevier"}]