[{"page":"8790 - 8794","date_published":"2008-06-24T00:00:00Z","date_updated":"2021-01-12T07:40:36Z","publist_id":"3666","intvolume":"       105","month":"06","title":"Auxin acts as a local morphogenetic trigger to specify lateral root founder cells","publication":"PNAS","issue":"25","type":"journal_article","year":"2008","citation":{"ama":"Dubrovsky J, Sauer M, Napsucialy Mendivil S, et al. Auxin acts as a local morphogenetic trigger to specify lateral root founder cells. <i>PNAS</i>. 2008;105(25):8790-8794. doi:<a href=\"https://doi.org/10.1073/pnas.0712307105\">10.1073/pnas.0712307105</a>","mla":"Dubrovsky, Joseph, et al. “Auxin Acts as a Local Morphogenetic Trigger to Specify Lateral Root Founder Cells.” <i>PNAS</i>, vol. 105, no. 25, National Academy of Sciences, 2008, pp. 8790–94, doi:<a href=\"https://doi.org/10.1073/pnas.0712307105\">10.1073/pnas.0712307105</a>.","short":"J. Dubrovsky, M. Sauer, S. Napsucialy Mendivil, M. Ivanchenko, J. Friml, S. Shishkova, J. Celenza, E. Benková, PNAS 105 (2008) 8790–8794.","ista":"Dubrovsky J, Sauer M, Napsucialy Mendivil S, Ivanchenko M, Friml J, Shishkova S, Celenza J, Benková E. 2008. Auxin acts as a local morphogenetic trigger to specify lateral root founder cells. PNAS. 105(25), 8790–8794.","chicago":"Dubrovsky, Joseph, Michael Sauer, Selene Napsucialy Mendivil, Maria Ivanchenko, Jiří Friml, Svetlana Shishkova, John Celenza, and Eva Benková. “Auxin Acts as a Local Morphogenetic Trigger to Specify Lateral Root Founder Cells.” <i>PNAS</i>. National Academy of Sciences, 2008. <a href=\"https://doi.org/10.1073/pnas.0712307105\">https://doi.org/10.1073/pnas.0712307105</a>.","ieee":"J. Dubrovsky <i>et al.</i>, “Auxin acts as a local morphogenetic trigger to specify lateral root founder cells,” <i>PNAS</i>, vol. 105, no. 25. National Academy of Sciences, pp. 8790–8794, 2008.","apa":"Dubrovsky, J., Sauer, M., Napsucialy Mendivil, S., Ivanchenko, M., Friml, J., Shishkova, S., … Benková, E. (2008). Auxin acts as a local morphogenetic trigger to specify lateral root founder cells. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.0712307105\">https://doi.org/10.1073/pnas.0712307105</a>"},"abstract":[{"text":"Plants exhibit an exceptional adaptability to different environmental conditions. To a large extent, this adaptability depends on their ability to initiate and form new organs throughout their entire postembryonic life. Plant shoot and root systems unceasingly branch and form axillary shoots or lateral roots, respectively. The first event in the formation of a new organ is specification of founder cells. Several plant hormones, prominent among them auxin, have been implicated in the acquisition of founder cell identity by differentiated cells, but the mechanisms underlying this process are largely elusive. Here, we show that auxin and its local accumulation in root pericycle cells is a necessary and sufficient signal to respecify these cells into lateral root founder cells. Analysis of the alf4-1 mutant suggests that specification of founder cells and the subsequent activation of cell division leading to primordium formation represent two genetically separable events. Time-lapse experiments show that the activation of an auxin response is the earliest detectable event in founder cell specification. Accordingly, local activation of auxin response correlates absolutely with the acquisition of founder cell identity and precedes the actual formation of a lateral root primordium through patterned cell division. Local production and subsequent accumulation of auxin in single pericycle cells induced by Cre-Lox-based activation of auxin synthesis converts them into founder cells. Thus, auxin is the local instructive signal that is sufficient for acquisition of founder cell identity and can be considered a morphogenetic trigger in postembryonic plant organogenesis.","lang":"eng"}],"volume":105,"status":"public","doi":"10.1073/pnas.0712307105","extern":1,"date_created":"2018-12-11T12:00:59Z","_id":"3036","publication_status":"published","publisher":"National Academy of Sciences","author":[{"first_name":"Joseph","full_name":"Dubrovsky, Joseph G","last_name":"Dubrovsky"},{"full_name":"Sauer, Michael","first_name":"Michael","last_name":"Sauer"},{"last_name":"Napsucialy Mendivil","first_name":"Selene","full_name":"Napsucialy-Mendivil, Selene"},{"first_name":"Maria","full_name":"Ivanchenko, Maria G","last_name":"Ivanchenko"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596"},{"last_name":"Shishkova","first_name":"Svetlana","full_name":"Shishkova, Svetlana"},{"last_name":"Celenza","full_name":"Celenza, John","first_name":"John"},{"first_name":"Eva","orcid":"0000-0002-8510-9739","full_name":"Eva Benková","last_name":"Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}],"day":"24","quality_controlled":0},{"publication":"Plant Physiology","title":"PIN polar targeting","language":[{"iso":"eng"}],"pmid":1,"year":"2008","issue":"4","type":"journal_article","doi":"10.1104/pp.108.121756","status":"public","volume":147,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Feraru E, Friml J. PIN polar targeting. <i>Plant Physiology</i>. 2008;147(4):1553-1559. doi:<a href=\"https://doi.org/10.1104/pp.108.121756\">10.1104/pp.108.121756</a>","mla":"Feraru, Elena, and Jiří Friml. “PIN Polar Targeting.” <i>Plant Physiology</i>, vol. 147, no. 4, American Society of Plant Biologists, 2008, pp. 1553–59, doi:<a href=\"https://doi.org/10.1104/pp.108.121756\">10.1104/pp.108.121756</a>.","ista":"Feraru E, Friml J. 2008. PIN polar targeting. Plant Physiology. 147(4), 1553–1559.","short":"E. Feraru, J. Friml, Plant Physiology 147 (2008) 1553–1559.","chicago":"Feraru, Elena, and Jiří Friml. “PIN Polar Targeting.” <i>Plant Physiology</i>. American Society of Plant Biologists, 2008. <a href=\"https://doi.org/10.1104/pp.108.121756\">https://doi.org/10.1104/pp.108.121756</a>.","ieee":"E. Feraru and J. Friml, “PIN polar targeting,” <i>Plant Physiology</i>, vol. 147, no. 4. American Society of Plant Biologists, pp. 1553–1559, 2008.","apa":"Feraru, E., &#38; Friml, J. (2008). PIN polar targeting. <i>Plant Physiology</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1104/pp.108.121756\">https://doi.org/10.1104/pp.108.121756</a>"},"quality_controlled":"1","day":"04","_id":"3037","publisher":"American Society of Plant Biologists","publication_status":"published","external_id":{"pmid":["18678746"]},"date_created":"2018-12-11T12:01:00Z","author":[{"first_name":"Elena","full_name":"Feraru, Elena","last_name":"Feraru"},{"last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí"}],"extern":"1","oa_version":"Published Version","oa":1,"date_published":"2008-08-04T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492634/"}],"page":"1553 - 1559","month":"08","intvolume":"       147","publist_id":"3664","date_updated":"2021-01-12T07:40:36Z"},{"day":"11","quality_controlled":0,"extern":1,"_id":"3038","date_created":"2018-12-11T12:01:00Z","publisher":"Nature Publishing Group","publication_status":"published","author":[{"first_name":"Kamal","full_name":"Swarup, Kamal","last_name":"Swarup"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","first_name":"Eva","full_name":"Eva Benková","orcid":"0000-0002-8510-9739"},{"last_name":"Swarup","first_name":"Ranjan","full_name":"Swarup, Ranjan"},{"first_name":"Ilda","full_name":"Casimiro, Ilda","last_name":"Casimiro"},{"full_name":"Péret, Benjamin","first_name":"Benjamin","last_name":"Péret"},{"last_name":"Yang","first_name":"Yaodong","full_name":"Yang, Yaodong"},{"last_name":"Parry","full_name":"Parry, Geraint","first_name":"Geraint"},{"full_name":"Nielsen, Erik","first_name":"Erik","last_name":"Nielsen"},{"last_name":"De Smet","full_name":"De Smet, Ive","first_name":"Ive"},{"full_name":"Vanneste, Steffen","first_name":"Steffen","last_name":"Vanneste"},{"last_name":"Levesque","first_name":"Mitchell","full_name":"Levesque, Mitchell P"},{"first_name":"David","full_name":"Carrier, David","last_name":"Carrier"},{"full_name":"James, Nicholas","first_name":"Nicholas","last_name":"James"},{"last_name":"Calvo","full_name":"Calvo, Vanessa","first_name":"Vanessa"},{"last_name":"Ljung","full_name":"Ljung, Karin","first_name":"Karin"},{"full_name":"Kramer, Eric","first_name":"Eric","last_name":"Kramer"},{"last_name":"Roberts","full_name":"Roberts, Rebecca","first_name":"Rebecca"},{"last_name":"Graham","first_name":"Neil","full_name":"Graham, Neil"},{"first_name":"Sylvestre","full_name":"Marillonnet, Sylvestre","last_name":"Marillonnet"},{"full_name":"Patel, Kanu","first_name":"Kanu","last_name":"Patel"},{"last_name":"Jones","first_name":"Jonathan","full_name":"Jones, Jonathan D"},{"last_name":"Taylor","first_name":"Christopher","full_name":"Taylor, Christopher G"},{"first_name":"Daniel","full_name":"Schachtman, Daniel P","last_name":"Schachtman"},{"first_name":"Sean","full_name":"May, Sean","last_name":"May"},{"first_name":"Göran","full_name":"Sandberg, Göran","last_name":"Sandberg"},{"first_name":"Philip","full_name":"Benfey, Philip N","last_name":"Benfey"},{"first_name":"Jirí","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kerr","first_name":"Ian","full_name":"Kerr, Ian"},{"last_name":"Beeckman","first_name":"Tom","full_name":"Beeckman, Tom"},{"full_name":"Laplaze, Laurent","first_name":"Laurent","last_name":"Laplaze"},{"full_name":"Bennett, Malcolm J","first_name":"Malcolm","last_name":"Bennett"}],"abstract":[{"lang":"eng","text":"Lateral roots originate deep within the parental root from a small number of founder cells at the periphery of vascular tissues and must emerge through intervening layers of tissues. We describe how the hormone auxin, which originates from the developing lateral root, acts as a local inductive signal which re-programmes adjacent cells. Auxin induces the expression of a previously uncharacterized auxin influx carrier LAX3 in cortical and epidermal cells directly overlaying new primordia. Increased LAX3 activity reinforces the auxin-dependent induction of a selection of cell-wall-remodelling enzymes, which are likely to promote cell separation in advance of developing lateral root primordia."}],"volume":10,"status":"public","doi":"10.1038/ncb1754","citation":{"chicago":"Swarup, Kamal, Eva Benková, Ranjan Swarup, Ilda Casimiro, Benjamin Péret, Yaodong Yang, Geraint Parry, et al. “The Auxin Influx Carrier LAX3 Promotes Lateral Root Emergence.” <i>Nature Cell Biology</i>. Nature Publishing Group, 2008. <a href=\"https://doi.org/10.1038/ncb1754\">https://doi.org/10.1038/ncb1754</a>.","ieee":"K. Swarup <i>et al.</i>, “The auxin influx carrier LAX3 promotes lateral root emergence,” <i>Nature Cell Biology</i>, vol. 10, no. 8. Nature Publishing Group, pp. 946–954, 2008.","apa":"Swarup, K., Benková, E., Swarup, R., Casimiro, I., Péret, B., Yang, Y., … Bennett, M. (2008). The auxin influx carrier LAX3 promotes lateral root emergence. <i>Nature Cell Biology</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncb1754\">https://doi.org/10.1038/ncb1754</a>","ama":"Swarup K, Benková E, Swarup R, et al. The auxin influx carrier LAX3 promotes lateral root emergence. <i>Nature Cell Biology</i>. 2008;10(8):946-954. doi:<a href=\"https://doi.org/10.1038/ncb1754\">10.1038/ncb1754</a>","mla":"Swarup, Kamal, et al. “The Auxin Influx Carrier LAX3 Promotes Lateral Root Emergence.” <i>Nature Cell Biology</i>, vol. 10, no. 8, Nature Publishing Group, 2008, pp. 946–54, doi:<a href=\"https://doi.org/10.1038/ncb1754\">10.1038/ncb1754</a>.","ista":"Swarup K, Benková E, Swarup R, Casimiro I, Péret B, Yang Y, Parry G, Nielsen E, De Smet I, Vanneste S, Levesque M, Carrier D, James N, Calvo V, Ljung K, Kramer E, Roberts R, Graham N, Marillonnet S, Patel K, Jones J, Taylor C, Schachtman D, May S, Sandberg G, Benfey P, Friml J, Kerr I, Beeckman T, Laplaze L, Bennett M. 2008. The auxin influx carrier LAX3 promotes lateral root emergence. Nature Cell Biology. 10(8), 946–954.","short":"K. Swarup, E. Benková, R. Swarup, I. Casimiro, B. Péret, Y. Yang, G. Parry, E. Nielsen, I. De Smet, S. Vanneste, M. Levesque, D. Carrier, N. James, V. Calvo, K. Ljung, E. Kramer, R. Roberts, N. Graham, S. Marillonnet, K. Patel, J. Jones, C. Taylor, D. Schachtman, S. May, G. Sandberg, P. Benfey, J. Friml, I. Kerr, T. Beeckman, L. Laplaze, M. Bennett, Nature Cell Biology 10 (2008) 946–954."},"issue":"8","type":"journal_article","year":"2008","title":"The auxin influx carrier LAX3 promotes lateral root emergence","publication":"Nature Cell Biology","intvolume":"        10","month":"07","date_updated":"2021-01-12T07:40:37Z","publist_id":"3665","date_published":"2008-07-11T00:00:00Z","page":"946 - 954"},{"title":"Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root","publication":"Science","type":"journal_article","issue":"5901","year":"2008","volume":322,"abstract":[{"lang":"eng","text":"During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation."}],"status":"public","doi":"10.1126/science.1160158","citation":{"chicago":"De Smet, Ive, Valya Vassileva, Bert De Rybel, Mitchell Levesque, Wim Grunewald, Daniël Van Damme, Giel Van Noorden, et al. “Receptor-like Kinase ACR4 Restricts Formative Cell Divisions in the Arabidopsis Root.” <i>Science</i>. American Association for the Advancement of Science, 2008. <a href=\"https://doi.org/10.1126/science.1160158\">https://doi.org/10.1126/science.1160158</a>.","ieee":"I. De Smet <i>et al.</i>, “Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root,” <i>Science</i>, vol. 322, no. 5901. American Association for the Advancement of Science, pp. 594–597, 2008.","apa":"De Smet, I., Vassileva, V., De Rybel, B., Levesque, M., Grunewald, W., Van Damme, D., … Beeckman, T. (2008). Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1160158\">https://doi.org/10.1126/science.1160158</a>","ama":"De Smet I, Vassileva V, De Rybel B, et al. Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root. <i>Science</i>. 2008;322(5901):594-597. doi:<a href=\"https://doi.org/10.1126/science.1160158\">10.1126/science.1160158</a>","mla":"De Smet, Ive, et al. “Receptor-like Kinase ACR4 Restricts Formative Cell Divisions in the Arabidopsis Root.” <i>Science</i>, vol. 322, no. 5901, American Association for the Advancement of Science, 2008, pp. 594–97, doi:<a href=\"https://doi.org/10.1126/science.1160158\">10.1126/science.1160158</a>.","ista":"De Smet I, Vassileva V, De Rybel B, Levesque M, Grunewald W, Van Damme D, Van Noorden G, Naudts M, Van Isterdael G, De Clercq R, Wang J, Meuli N, Vanneste S, Friml J, Hilson P, Jürgens G, Ingram G, Inzé D, Benfey P, Beeckman T. 2008. Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root. Science. 322(5901), 594–597.","short":"I. De Smet, V. Vassileva, B. De Rybel, M. Levesque, W. Grunewald, D. Van Damme, G. Van Noorden, M. Naudts, G. Van Isterdael, R. De Clercq, J. Wang, N. Meuli, S. Vanneste, J. Friml, P. Hilson, G. Jürgens, G. Ingram, D. Inzé, P. Benfey, T. Beeckman, Science 322 (2008) 594–597."},"day":"24","quality_controlled":0,"extern":1,"_id":"3039","author":[{"last_name":"De Smet","first_name":"Ive","full_name":"De Smet, Ive"},{"first_name":"Valya","full_name":"Vassileva, Valya","last_name":"Vassileva"},{"last_name":"De Rybel","first_name":"Bert","full_name":"De Rybel, Bert"},{"last_name":"Levesque","full_name":"Levesque, Mitchell P","first_name":"Mitchell"},{"last_name":"Grunewald","full_name":"Grunewald, Wim","first_name":"Wim"},{"last_name":"Van Damme","first_name":"Daniël","full_name":"Van Damme, Daniël"},{"full_name":"Van Noorden, Giel","first_name":"Giel","last_name":"Van Noorden"},{"full_name":"Naudts, Mirande","first_name":"Mirande","last_name":"Naudts"},{"first_name":"Gert","full_name":"Van Isterdael, Gert","last_name":"Van Isterdael"},{"last_name":"De Clercq","full_name":"De Clercq, Rebecca","first_name":"Rebecca"},{"last_name":"Wang","full_name":"Wang, Jean Y","first_name":"Jean"},{"last_name":"Meuli","full_name":"Meuli, Nicholas","first_name":"Nicholas"},{"first_name":"Steffen","full_name":"Vanneste, Steffen","last_name":"Vanneste"},{"full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml"},{"last_name":"Hilson","full_name":"Hilson, Pierre","first_name":"Pierre"},{"last_name":"Jürgens","full_name":"Jürgens, Gerd","first_name":"Gerd"},{"last_name":"Ingram","first_name":"Gwyneth","full_name":"Ingram, Gwyneth C"},{"first_name":"Dirk","full_name":"Inzé, Dirk","last_name":"Inzé"},{"first_name":"Philip","full_name":"Benfey, Philip N","last_name":"Benfey"},{"full_name":"Beeckman, Tom","first_name":"Tom","last_name":"Beeckman"}],"publisher":"American Association for the Advancement of Science","publication_status":"published","date_created":"2018-12-11T12:01:00Z","date_published":"2008-10-24T00:00:00Z","page":"594 - 597","intvolume":"       322","month":"10","date_updated":"2021-01-12T07:40:37Z","publist_id":"3663"},{"extern":1,"date_created":"2018-12-11T12:01:01Z","_id":"3040","publication_status":"published","publisher":"Oxford University Press","author":[{"full_name":"Kleine-Vehn, Jürgen","first_name":"Jürgen","last_name":"Kleine Vehn"},{"full_name":"Łangowski, Łukasz","first_name":"Łukasz","last_name":"Łangowski"},{"full_name":"Wiśniewska, Justyna","first_name":"Justyna","last_name":"Wiśniewska"},{"first_name":"Pankaj","full_name":"Dhonukshe, Pankaj","last_name":"Dhonukshe"},{"first_name":"Philip","full_name":"Brewer, Philip B","last_name":"Brewer"},{"last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml","first_name":"Jirí"}],"day":"01","quality_controlled":0,"citation":{"chicago":"Kleine Vehn, Jürgen, Łukasz Łangowski, Justyna Wiśniewska, Pankaj Dhonukshe, Philip Brewer, and Jiří Friml. “Cellular and Molecular Requirements for Polar PIN Targeting and Transcytosis in Plants.” <i>Molecular Plant</i>. Oxford University Press, 2008. <a href=\"https://doi.org/10.1093/mp/ssn062\">https://doi.org/10.1093/mp/ssn062</a>.","apa":"Kleine Vehn, J., Łangowski, Ł., Wiśniewska, J., Dhonukshe, P., Brewer, P., &#38; Friml, J. (2008). Cellular and molecular requirements for polar PIN targeting and transcytosis in plants. <i>Molecular Plant</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mp/ssn062\">https://doi.org/10.1093/mp/ssn062</a>","ieee":"J. Kleine Vehn, Ł. Łangowski, J. Wiśniewska, P. Dhonukshe, P. Brewer, and J. Friml, “Cellular and molecular requirements for polar PIN targeting and transcytosis in plants,” <i>Molecular Plant</i>, vol. 1, no. 6. Oxford University Press, pp. 1056–1066, 2008.","mla":"Kleine Vehn, Jürgen, et al. “Cellular and Molecular Requirements for Polar PIN Targeting and Transcytosis in Plants.” <i>Molecular Plant</i>, vol. 1, no. 6, Oxford University Press, 2008, pp. 1056–66, doi:<a href=\"https://doi.org/10.1093/mp/ssn062\">10.1093/mp/ssn062</a>.","ama":"Kleine Vehn J, Łangowski Ł, Wiśniewska J, Dhonukshe P, Brewer P, Friml J. Cellular and molecular requirements for polar PIN targeting and transcytosis in plants. <i>Molecular Plant</i>. 2008;1(6):1056-1066. doi:<a href=\"https://doi.org/10.1093/mp/ssn062\">10.1093/mp/ssn062</a>","short":"J. Kleine Vehn, Ł. Łangowski, J. Wiśniewska, P. Dhonukshe, P. Brewer, J. Friml, Molecular Plant 1 (2008) 1056–1066.","ista":"Kleine Vehn J, Łangowski Ł, Wiśniewska J, Dhonukshe P, Brewer P, Friml J. 2008. Cellular and molecular requirements for polar PIN targeting and transcytosis in plants. Molecular Plant. 1(6), 1056–1066."},"volume":1,"abstract":[{"text":"The polar, sub-cellular localization of PIN auxin efflux carriers determines the direction of intercellular auxin flow, thus defining the spatial aspect of auxin signalling. Dynamic, transcytosis-like relocalizations of PIN proteins occur in response to external and internal signals, integrating these signals into changes in auxin distribution. Here, we examine the cellular and molecular mechanisms of polar PIN delivery and transcytosis. The mechanisms of the ARF-GEF-dependent polar targeting and transcytosis are well conserved and show little variations among diverse Arabidopsis ecotypes consistent with their fundamental importance in regulating plant development. At the cellular level, we refine previous findings on the role of the actin cytoskeleton in apical and basal PIN targeting, and identify a previously unknown role for microtubules, specifically in basal targeting. PIN protein delivery to different sides of the cell is mediated by ARF-dependent trafficking with a previously unknown complex level of distinct ARF-GEF vesicle trafficking regulators. Our data suggest that alternative recruitment of PIN proteins by these distinct pathways can account for cell type- and cargo-specific aspects of polar targeting, as well as for polarity changes in response to different signals. The resulting dynamic PIN positioning to different sides of cells defines a three-dimensional pattern of auxin fluxes within plant tissues.","lang":"eng"}],"doi":"10.1093/mp/ssn062","status":"public","type":"journal_article","year":"2008","issue":"6","title":"Cellular and molecular requirements for polar PIN targeting and transcytosis in plants","publication":"Molecular Plant","date_updated":"2021-01-12T07:40:38Z","publist_id":"3662","intvolume":"         1","month":"01","page":"1056 - 1066","date_published":"2008-01-01T00:00:00Z"},{"year":"2008","type":"journal_article","issue":"45","title":"Flavonoids redirect PIN mediated polar auxin fluxes during root gravitropic responses","publication":"Journal of Biological Chemistry","day":"07","quality_controlled":0,"extern":1,"publisher":"American Society for Biochemistry and Molecular Biology","_id":"3041","date_created":"2018-12-11T12:01:01Z","publication_status":"published","author":[{"first_name":"Diana","full_name":"Santelia, Diana","last_name":"Santelia"},{"first_name":"Sina","full_name":"Henrichs, Sina","last_name":"Henrichs"},{"full_name":"Vincenzetti, Vincent","first_name":"Vincent","last_name":"Vincenzetti"},{"full_name":"Sauer, Michael","first_name":"Michael","last_name":"Sauer"},{"full_name":"Bigler, Laurent","first_name":"Laurent","last_name":"Bigler"},{"last_name":"Klein","first_name":"Markus","full_name":"Klein, Markus B"},{"first_name":"Aurélien","full_name":"Bailly, Aurélien","last_name":"Bailly"},{"first_name":"Yuree","full_name":"Lee, Yuree","last_name":"Lee"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596"},{"first_name":"Markus","full_name":"Geisler, Markus","last_name":"Geisler"},{"first_name":"Enrico","full_name":"Martinoia, Enrico","last_name":"Martinoia"}],"abstract":[{"text":"The rate, polarity, and symmetry of the flow of the plant hormone auxin are determined by the polar cellular localization of PIN-FORMED (PIN) auxin efflux carriers. Flavonoids, a class of secondary plant metabolites, have been suspected to modulate auxin transport and tropic responses. Nevertheless, the identity of specific flavonoid compounds involved and their molecular function and targets in vivo are essentially unknown. Here we show that the root elongation zone of agravitropic pin2/eir1/wav6/agr1 has an altered pattern and amount of flavonol glycosides. Application of nanomolar concentrations of flavonols to pin2 roots is sufficient to partially restore root gravitropism. By employing a quantitative cell biological approach, we demonstrate that flavonoids partially restore the formation of lateral auxin gradients in the absence of PIN2. Chemical complementation by flavonoids correlates with an asymmetric distribution of the PIN1 protein. pin2 complementation probably does not result from inhibition of auxin efflux, as supply of the auxin transport inhibitor N-1-naphthylphthalamic acid failed to restore pin2 gravitropism. We propose that flavonoids promote asymmetric PIN shifts during gravity stimulation, thus redirecting basipetal auxin streams necessary for root bending. © 2008 by The American Society for Biochemistry and Molecular Biology, Inc.","lang":"eng"}],"volume":283,"doi":" 10.1074/jbc.M710122200","status":"public","citation":{"apa":"Santelia, D., Henrichs, S., Vincenzetti, V., Sauer, M., Bigler, L., Klein, M., … Martinoia, E. (2008). Flavonoids redirect PIN mediated polar auxin fluxes during root gravitropic responses. <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href=\"https://doi.org/ 10.1074/jbc.M710122200\">https://doi.org/ 10.1074/jbc.M710122200</a>","ieee":"D. Santelia <i>et al.</i>, “Flavonoids redirect PIN mediated polar auxin fluxes during root gravitropic responses,” <i>Journal of Biological Chemistry</i>, vol. 283, no. 45. American Society for Biochemistry and Molecular Biology, pp. 31218–31226, 2008.","chicago":"Santelia, Diana, Sina Henrichs, Vincent Vincenzetti, Michael Sauer, Laurent Bigler, Markus Klein, Aurélien Bailly, et al. “Flavonoids Redirect PIN Mediated Polar Auxin Fluxes during Root Gravitropic Responses.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2008. <a href=\"https://doi.org/ 10.1074/jbc.M710122200\">https://doi.org/ 10.1074/jbc.M710122200</a>.","ista":"Santelia D, Henrichs S, Vincenzetti V, Sauer M, Bigler L, Klein M, Bailly A, Lee Y, Friml J, Geisler M, Martinoia E. 2008. Flavonoids redirect PIN mediated polar auxin fluxes during root gravitropic responses. Journal of Biological Chemistry. 283(45), 31218–31226.","short":"D. Santelia, S. Henrichs, V. Vincenzetti, M. Sauer, L. Bigler, M. Klein, A. Bailly, Y. Lee, J. Friml, M. Geisler, E. Martinoia, Journal of Biological Chemistry 283 (2008) 31218–31226.","mla":"Santelia, Diana, et al. “Flavonoids Redirect PIN Mediated Polar Auxin Fluxes during Root Gravitropic Responses.” <i>Journal of Biological Chemistry</i>, vol. 283, no. 45, American Society for Biochemistry and Molecular Biology, 2008, pp. 31218–26, doi:<a href=\"https://doi.org/ 10.1074/jbc.M710122200\"> 10.1074/jbc.M710122200</a>.","ama":"Santelia D, Henrichs S, Vincenzetti V, et al. Flavonoids redirect PIN mediated polar auxin fluxes during root gravitropic responses. <i>Journal of Biological Chemistry</i>. 2008;283(45):31218-31226. doi:<a href=\"https://doi.org/ 10.1074/jbc.M710122200\"> 10.1074/jbc.M710122200</a>"},"intvolume":"       283","month":"11","date_updated":"2021-01-12T07:40:38Z","publist_id":"3661","date_published":"2008-11-07T00:00:00Z","page":"31218 - 31226"},{"page":"17812 - 17817","date_published":"2008-11-18T00:00:00Z","publist_id":"3659","date_updated":"2021-01-12T07:40:39Z","month":"11","intvolume":"       105","citation":{"mla":"Kleine Vehn, Jürgen, et al. “Differential Degradation of PIN2 Auxin Efflux Carrier by Retromer Dependent Vacuolar Targeting.” <i>PNAS</i>, vol. 105, no. 46, National Academy of Sciences, 2008, pp. 17812–17, doi:<a href=\"https://doi.org/10.1073/pnas.0808073105\">10.1073/pnas.0808073105</a>.","ama":"Kleine Vehn J, Leitner J, Zwiewka M, et al. Differential degradation of PIN2 auxin efflux carrier by retromer dependent vacuolar targeting. <i>PNAS</i>. 2008;105(46):17812-17817. doi:<a href=\"https://doi.org/10.1073/pnas.0808073105\">10.1073/pnas.0808073105</a>","short":"J. Kleine Vehn, J. Leitner, M. Zwiewka, M. Sauer, L. Abas, C. Luschnig, J. Friml, PNAS 105 (2008) 17812–17817.","ista":"Kleine Vehn J, Leitner J, Zwiewka M, Sauer M, Abas L, Luschnig C, Friml J. 2008. Differential degradation of PIN2 auxin efflux carrier by retromer dependent vacuolar targeting. PNAS. 105(46), 17812–17817.","chicago":"Kleine Vehn, Jürgen, Johannes Leitner, Marta Zwiewka, Michael Sauer, Lindy Abas, Christian Luschnig, and Jiří Friml. “Differential Degradation of PIN2 Auxin Efflux Carrier by Retromer Dependent Vacuolar Targeting.” <i>PNAS</i>. National Academy of Sciences, 2008. <a href=\"https://doi.org/10.1073/pnas.0808073105\">https://doi.org/10.1073/pnas.0808073105</a>.","apa":"Kleine Vehn, J., Leitner, J., Zwiewka, M., Sauer, M., Abas, L., Luschnig, C., &#38; Friml, J. (2008). Differential degradation of PIN2 auxin efflux carrier by retromer dependent vacuolar targeting. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.0808073105\">https://doi.org/10.1073/pnas.0808073105</a>","ieee":"J. Kleine Vehn <i>et al.</i>, “Differential degradation of PIN2 auxin efflux carrier by retromer dependent vacuolar targeting,” <i>PNAS</i>, vol. 105, no. 46. National Academy of Sciences, pp. 17812–17817, 2008."},"doi":"10.1073/pnas.0808073105","status":"public","volume":105,"abstract":[{"lang":"eng","text":"All eukaryotic cells present at the cell surface a specific set of plasma membrane proteins that modulate responses to internal and external cues and whose activity is also regulated by protein degradation. We characterized the lytic vacuole-dependent degradation of membrane proteins in Arabidopsis thaliana by means of in vivo visualization of vacuolar targeting combined with quantitative protein analysis. We show that the vacuolar targeting pathway is used by multiple cargos including PIN-FORMED (PIN) efflux carriers for the phytohormone auxin. In vivo visualization of PIN2 vacuolar targeting revealed its differential degradation in response to environmental signals, such as gravity. In contrast to polar PIN delivery to the basal plasma membrane, which depends on the vesicle trafficking regulator ARF-GEF GNOM, PIN sorting to the lytic vacuolar pathway requires additional brefeldin A-sensitive ARF-GEF activity. Furthermore, we identified putative retromer components SORTING NEXIN1 (SNX1) and VACUOLAR PROTEIN SORTING29 (VPS29) as important factors in this pathway and propose that the retromer complex acts to retrieve PIN proteins from a late/pre-vacuolar compartment back to the recycling pathways. Our data suggest that ARF GEF- and retromer-dependent processes regulate PIN sorting to the vacuole in an antagonistic manner and illustrate instrumentalization of this mechanism for fine-tuning the auxin fluxes during gravitropic response."}],"_id":"3042","publisher":"National Academy of Sciences","date_created":"2018-12-11T12:01:01Z","publication_status":"published","author":[{"full_name":"Kleine-Vehn, Jürgen","first_name":"Jürgen","last_name":"Kleine Vehn"},{"last_name":"Leitner","first_name":"Johannes","full_name":"Leitner, Johannes"},{"full_name":"Zwiewka, Marta","first_name":"Marta","last_name":"Zwiewka"},{"first_name":"Michael","full_name":"Sauer, Michael","last_name":"Sauer"},{"full_name":"Abas, Lindy","first_name":"Lindy","last_name":"Abas"},{"last_name":"Luschnig","first_name":"Christian","full_name":"Luschnig, Christian"},{"last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml"}],"extern":1,"quality_controlled":0,"day":"18","publication":"PNAS","title":"Differential degradation of PIN2 auxin efflux carrier by retromer dependent vacuolar targeting","year":"2008","type":"journal_article","issue":"46"},{"quality_controlled":"1","day":"10","_id":"3043","publication_status":"published","publisher":"Annual Reviews","date_created":"2018-12-11T12:01:02Z","external_id":{"pmid":["    18837671"]},"author":[{"first_name":"Jürgen","full_name":"Kleine Vehn, Jürgen","last_name":"Kleine Vehn"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","first_name":"Jirí","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"extern":"1","doi":"10.1146/annurev.cellbio.24.110707.175254","status":"public","abstract":[{"lang":"eng","text":"Plant development is characterized by a profound phenotypic plasticity that often involves redefining of the developmental fate and polarity of cells within differentiated tissues. The plant hormone auxin and its directional intercellular transport play a major role in these processes because they provide positional information and link cell polarity with tissue patterning. This plant-specific mechanism of transport-dependent auxin gradients depends on subcellular dynamics of auxin transport components, in particular on endocytic recycling and polar targeting. Recent insights into these cellular processes in plants have revealed important parallels to yeast and animal systems, including clathrin-dependent endocytosis, retromer function, and transcytosis, but have also emphasized unique features of plant cells such as diversity of polar targeting pathways; integration of environmental signals into subcellular trafficking; and the link between endocytosis, cell polarity, and cell fate specification. We review these advances and focus on the translation of the subcellular dynamics to the regulation of whole-plant development."}],"volume":24,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"short":"J. Kleine Vehn, J. Friml, Annual Review of Cell and Developmental Biology 24 (2008) 447–473.","ista":"Kleine Vehn J, Friml J. 2008. Polar targeting and endocytic recycling in auxin-dependent plant development. Annual Review of Cell and Developmental Biology. 24, 447–473.","mla":"Kleine Vehn, Jürgen, and Jiří Friml. “Polar Targeting and Endocytic Recycling in Auxin-Dependent Plant Development.” <i>Annual Review of Cell and Developmental Biology</i>, vol. 24, Annual Reviews, 2008, pp. 447–73, doi:<a href=\"https://doi.org/10.1146/annurev.cellbio.24.110707.175254\">10.1146/annurev.cellbio.24.110707.175254</a>.","ama":"Kleine Vehn J, Friml J. Polar targeting and endocytic recycling in auxin-dependent plant development. <i>Annual Review of Cell and Developmental Biology</i>. 2008;24:447-473. doi:<a href=\"https://doi.org/10.1146/annurev.cellbio.24.110707.175254\">10.1146/annurev.cellbio.24.110707.175254</a>","apa":"Kleine Vehn, J., &#38; Friml, J. (2008). Polar targeting and endocytic recycling in auxin-dependent plant development. <i>Annual Review of Cell and Developmental Biology</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev.cellbio.24.110707.175254\">https://doi.org/10.1146/annurev.cellbio.24.110707.175254</a>","ieee":"J. Kleine Vehn and J. Friml, “Polar targeting and endocytic recycling in auxin-dependent plant development,” <i>Annual Review of Cell and Developmental Biology</i>, vol. 24. Annual Reviews, pp. 447–473, 2008.","chicago":"Kleine Vehn, Jürgen, and Jiří Friml. “Polar Targeting and Endocytic Recycling in Auxin-Dependent Plant Development.” <i>Annual Review of Cell and Developmental Biology</i>. Annual Reviews, 2008. <a href=\"https://doi.org/10.1146/annurev.cellbio.24.110707.175254\">https://doi.org/10.1146/annurev.cellbio.24.110707.175254</a>."},"pmid":1,"type":"journal_article","year":"2008","publication":"Annual Review of Cell and Developmental Biology","title":"Polar targeting and endocytic recycling in auxin-dependent plant development","language":[{"iso":"eng"}],"month":"11","intvolume":"        24","publist_id":"3660","date_updated":"2021-01-12T07:40:39Z","date_published":"2008-11-10T00:00:00Z","page":"447 - 473","oa_version":"None"},{"date_updated":"2021-01-12T07:40:39Z","publist_id":"3658","intvolume":"       135","month":"10","page":"3345 - 3354","date_published":"2008-10-15T00:00:00Z","type":"journal_article","year":"2008","issue":"20","title":"Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development","publication":"Development","extern":1,"publisher":"Company of Biologists","_id":"3044","date_created":"2018-12-11T12:01:02Z","publication_status":"published","author":[{"last_name":"Mravec","first_name":"Jozef","full_name":"Mravec, Jozef"},{"full_name":"Kubeš, Martin","first_name":"Martin","last_name":"Kubeš"},{"first_name":"Agnieszka","full_name":"Bielach, Agnieszka","last_name":"Bielach"},{"first_name":"Vassilena","full_name":"Gaykova, Vassilena","last_name":"Gaykova"},{"first_name":"Jan","full_name":"Petrášek, Jan","last_name":"Petrášek"},{"last_name":"Skůpa","full_name":"Skůpa, Petr","first_name":"Petr"},{"last_name":"Chand","full_name":"Chand, Suresh","first_name":"Suresh"},{"full_name":"Eva Benková","orcid":"0000-0002-8510-9739","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková"},{"last_name":"Zažímalová","first_name":"Eva","full_name":"Zažímalová, Eva"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","first_name":"Jirí"}],"day":"15","quality_controlled":0,"citation":{"chicago":"Mravec, Jozef, Martin Kubeš, Agnieszka Bielach, Vassilena Gaykova, Jan Petrášek, Petr Skůpa, Suresh Chand, Eva Benková, Eva Zažímalová, and Jiří Friml. “Interaction of PIN and PGP Transport Mechanisms in Auxin Distribution-Dependent Development.” <i>Development</i>. Company of Biologists, 2008. <a href=\"https://doi.org/10.1242/dev.021071\">https://doi.org/10.1242/dev.021071</a>.","ieee":"J. Mravec <i>et al.</i>, “Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development,” <i>Development</i>, vol. 135, no. 20. Company of Biologists, pp. 3345–3354, 2008.","apa":"Mravec, J., Kubeš, M., Bielach, A., Gaykova, V., Petrášek, J., Skůpa, P., … Friml, J. (2008). Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. <i>Development</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/dev.021071\">https://doi.org/10.1242/dev.021071</a>","ama":"Mravec J, Kubeš M, Bielach A, et al. Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. <i>Development</i>. 2008;135(20):3345-3354. doi:<a href=\"https://doi.org/10.1242/dev.021071\">10.1242/dev.021071</a>","mla":"Mravec, Jozef, et al. “Interaction of PIN and PGP Transport Mechanisms in Auxin Distribution-Dependent Development.” <i>Development</i>, vol. 135, no. 20, Company of Biologists, 2008, pp. 3345–54, doi:<a href=\"https://doi.org/10.1242/dev.021071\">10.1242/dev.021071</a>.","short":"J. Mravec, M. Kubeš, A. Bielach, V. Gaykova, J. Petrášek, P. Skůpa, S. Chand, E. Benková, E. Zažímalová, J. Friml, Development 135 (2008) 3345–3354.","ista":"Mravec J, Kubeš M, Bielach A, Gaykova V, Petrášek J, Skůpa P, Chand S, Benková E, Zažímalová E, Friml J. 2008. Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. Development. 135(20), 3345–3354."},"volume":135,"abstract":[{"text":"The signalling molecule auxin controls plant morphogenesis via its activity gradients, which are produced by intercellular auxin transport. Cellular auxin efflux is the rate-limiting step in this process and depends on PIN and phosphoglycoprotein (PGP) auxin transporters. Mutual roles for these proteins in auxin transport are unclear, as is the significance of their interactions for plant development. Here, we have analysed the importance of the functional interaction between PIN- and PGP-dependent auxin transport in development. We show by analysis of inducible overexpression lines that PINs and PGPs define distinct auxin transport mechanisms: both mediate auxin efflux but they play diverse developmental roles. Components of both systems are expressed during embryogenesis, organogenesis and tropisms, and they interact genetically in both synergistic and antagonistic fashions. A concerted action of PIN- and PGP-dependent efflux systems is required for asymmetric auxin distribution during these processes. We propose a model in which PGP-mediated efflux controls auxin levels in auxin channel-forming cells and, thus, auxin availability for PIN-dependent vectorial auxin movement.","lang":"eng"}],"status":"public","doi":"10.1242/dev.021071"},{"page":"962 - 966","date_published":"2008-12-18T00:00:00Z","publist_id":"3657","date_updated":"2021-01-12T07:40:40Z","month":"12","intvolume":"       456","publication":"Nature","title":"Generation of cell polarity in plants links endocytosis auxin distribution and cell fate decisions","issue":"7224","year":"2008","type":"journal_article","citation":{"ista":"Dhonukshe P, Tanaka H, Goh T, Ebine K, Mähönen A, Prasad K, Blilou I, Geldner N, Xu J, Uemura T, Chory J, Ueda T, Nakano A, Scheres B, Friml J. 2008. Generation of cell polarity in plants links endocytosis auxin distribution and cell fate decisions. Nature. 456(7224), 962–966.","short":"P. Dhonukshe, H. Tanaka, T. Goh, K. Ebine, A. Mähönen, K. Prasad, I. Blilou, N. Geldner, J. Xu, T. Uemura, J. Chory, T. Ueda, A. Nakano, B. Scheres, J. Friml, Nature 456 (2008) 962–966.","mla":"Dhonukshe, Pankaj, et al. “Generation of Cell Polarity in Plants Links Endocytosis Auxin Distribution and Cell Fate Decisions.” <i>Nature</i>, vol. 456, no. 7224, Nature Publishing Group, 2008, pp. 962–66, doi:<a href=\"https://doi.org/10.1038/nature07409\">10.1038/nature07409</a>.","ama":"Dhonukshe P, Tanaka H, Goh T, et al. Generation of cell polarity in plants links endocytosis auxin distribution and cell fate decisions. <i>Nature</i>. 2008;456(7224):962-966. doi:<a href=\"https://doi.org/10.1038/nature07409\">10.1038/nature07409</a>","apa":"Dhonukshe, P., Tanaka, H., Goh, T., Ebine, K., Mähönen, A., Prasad, K., … Friml, J. (2008). Generation of cell polarity in plants links endocytosis auxin distribution and cell fate decisions. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature07409\">https://doi.org/10.1038/nature07409</a>","ieee":"P. Dhonukshe <i>et al.</i>, “Generation of cell polarity in plants links endocytosis auxin distribution and cell fate decisions,” <i>Nature</i>, vol. 456, no. 7224. Nature Publishing Group, pp. 962–966, 2008.","chicago":"Dhonukshe, Pankaj, Hirokazu Tanaka, Tatsuaki Goh, Kazuo Ebine, Ari Mähönen, Kalika Prasad, Ikram Blilou, et al. “Generation of Cell Polarity in Plants Links Endocytosis Auxin Distribution and Cell Fate Decisions.” <i>Nature</i>. Nature Publishing Group, 2008. <a href=\"https://doi.org/10.1038/nature07409\">https://doi.org/10.1038/nature07409</a>."},"status":"public","doi":"10.1038/nature07409","volume":456,"abstract":[{"text":"Dynamically polarized membrane proteins define different cell boundaries and have an important role in intercellular communication - a vital feature of multicellular development. Efflux carriers for the signalling molecule auxin from the PIN family are landmarks of cell polarity in plants and have a crucial involvement in auxin distribution-dependent development including embryo patterning, organogenesis and tropisms. Polar PIN localization determines the direction of intercellular auxin flow, yet the mechanisms generating PIN polarity remain unclear. Here we identify an endocytosis-dependent mechanism of PIN polarity generation and analyse its developmental implications. Real-time PIN tracking showed that after synthesis, PINs are initially delivered to the plasma membrane in a non-polar manner and their polarity is established by subsequent endocytic recycling. Interference with PIN endocytosis either by auxin or by manipulation of the Arabidopsis Rab5 GTPase pathway prevents PIN polarization. Failure of PIN polarization transiently alters asymmetric auxin distribution during embryogenesis and increases the local auxin response in apical embryo regions. This results in ectopic expression of auxin pathway-associated root-forming master regulators in embryonic leaves and promotes homeotic transformation of leaves to roots. Our results indicate a two-step mechanism for the generation of PIN polar localization and the essential role of endocytosis in this process. It also highlights the link between endocytosis-dependent polarity of individual cells and auxin distribution-dependent cell fate establishment for multicellular patterning.","lang":"eng"}],"publication_status":"published","_id":"3045","author":[{"last_name":"Dhonukshe","full_name":"Dhonukshe, Pankaj","first_name":"Pankaj"},{"last_name":"Tanaka","first_name":"Hirokazu","full_name":"Tanaka, Hirokazu"},{"last_name":"Goh","first_name":"Tatsuaki","full_name":"Goh, Tatsuaki"},{"full_name":"Ebine, Kazuo","first_name":"Kazuo","last_name":"Ebine"},{"last_name":"Mähönen","full_name":"Mähönen, Ari Pekka","first_name":"Ari"},{"last_name":"Prasad","first_name":"Kalika","full_name":"Prasad, Kalika"},{"first_name":"Ikram","full_name":"Blilou, Ikram","last_name":"Blilou"},{"last_name":"Geldner","first_name":"Niko","full_name":"Geldner, Niko"},{"first_name":"Jian","full_name":"Xu, Jian","last_name":"Xu"},{"full_name":"Uemura, Tomohiro","first_name":"Tomohiro","last_name":"Uemura"},{"last_name":"Chory","full_name":"Chory, Joanne","first_name":"Joanne"},{"last_name":"Ueda","full_name":"Ueda, Takashi","first_name":"Takashi"},{"full_name":"Nakano, Akihiko","first_name":"Akihiko","last_name":"Nakano"},{"first_name":"Ben","full_name":"Scheres, Ben","last_name":"Scheres"},{"orcid":"0000-0002-8302-7596","full_name":"Jirí Friml","first_name":"Jirí","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2018-12-11T12:01:02Z","publisher":"Nature Publishing Group","extern":1,"quality_controlled":0,"day":"18"},{"citation":{"chicago":"Pellicciotti, Francesca, Jakob Helbing, Andrés Rivera, Vincent Favier, Javier Corripio, José Araos, Jean-Emmanuel Sicart, and Marco Carenzo. “A Study of the Energy Balance and Melt Regime on Juncal Norte Glacier, Semi-Arid Andes of Central Chile, Using Melt Models of Different Complexity.” <i>Hydrological Processes</i>. Wiley, 2008. <a href=\"https://doi.org/10.1002/hyp.7085\">https://doi.org/10.1002/hyp.7085</a>.","ieee":"F. Pellicciotti <i>et al.</i>, “A study of the energy balance and melt regime on Juncal Norte Glacier, semi-arid Andes of central Chile, using melt models of different complexity,” <i>Hydrological Processes</i>, vol. 22, no. 19. Wiley, pp. 3980–3997, 2008.","apa":"Pellicciotti, F., Helbing, J., Rivera, A., Favier, V., Corripio, J., Araos, J., … Carenzo, M. (2008). A study of the energy balance and melt regime on Juncal Norte Glacier, semi-arid Andes of central Chile, using melt models of different complexity. <i>Hydrological Processes</i>. Wiley. <a href=\"https://doi.org/10.1002/hyp.7085\">https://doi.org/10.1002/hyp.7085</a>","ama":"Pellicciotti F, Helbing J, Rivera A, et al. A study of the energy balance and melt regime on Juncal Norte Glacier, semi-arid Andes of central Chile, using melt models of different complexity. <i>Hydrological Processes</i>. 2008;22(19):3980-3997. doi:<a href=\"https://doi.org/10.1002/hyp.7085\">10.1002/hyp.7085</a>","mla":"Pellicciotti, Francesca, et al. “A Study of the Energy Balance and Melt Regime on Juncal Norte Glacier, Semi-Arid Andes of Central Chile, Using Melt Models of Different Complexity.” <i>Hydrological Processes</i>, vol. 22, no. 19, Wiley, 2008, pp. 3980–97, doi:<a href=\"https://doi.org/10.1002/hyp.7085\">10.1002/hyp.7085</a>.","ista":"Pellicciotti F, Helbing J, Rivera A, Favier V, Corripio J, Araos J, Sicart J-E, Carenzo M. 2008. A study of the energy balance and melt regime on Juncal Norte Glacier, semi-arid Andes of central Chile, using melt models of different complexity. Hydrological Processes. 22(19), 3980–3997.","short":"F. Pellicciotti, J. Helbing, A. Rivera, V. Favier, J. Corripio, J. Araos, J.-E. Sicart, M. Carenzo, Hydrological Processes 22 (2008) 3980–3997."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","volume":22,"date_created":"2023-02-20T08:18:45Z","quality_controlled":"1","scopus_import":"1","language":[{"iso":"eng"}],"publication":"Hydrological Processes","title":"A study of the energy balance and melt regime on Juncal Norte Glacier, semi-arid Andes of central Chile, using melt models of different complexity","year":"2008","type":"journal_article","issue":"19","page":"3980-3997","date_published":"2008-09-15T00:00:00Z","intvolume":"        22","publication_identifier":{"eissn":["1099-1085"],"issn":["0885-6087"]},"doi":"10.1002/hyp.7085","article_processing_charge":"No","abstract":[{"lang":"eng","text":"We use meteorological data from two automatic weather stations (AWS) on Juncal Norte Glacier, central Chile, to investigate the glacier–climate interaction and to test ablation models of different complexity. The semi-arid Central Andes are characterized by dry summers, with precipitation close to zero, low relative humidity and intense solar radiation. We show that katabatic forcing is dominant both on the glacier tongue and in the fore field, and that low humidity and absence of clouds cause strong radiative cooling of the glacier surface. Surface albedo is basically constant for snow and ice, because of the scarcity of solid precipitation. The energy balance of the glacier is simulated for a 2-month period in austral summer using two models of different complexity, which differ in the inclusion of the heat conduction flux into the snowpack and in the parameterization of the incoming longwave radiation. Net shortwave radiation is the dominant component of the energy balance. The sensible heat flux is always positive, while both the net longwave radiation and latent heat flux are negative. Neglecting the subsurface heat flux and corresponding variations in surface temperature leads to an overestimation of ablation of 2% over a total of 3695 mm water equivalent (w.e.) at the end of the season. Correct modelling of incoming longwave radiation is crucial, and we suggest that parameterizations based on vapour pressure and air temperature should be used rather than on computed cloud amount. We also used an enhanced temperature-index model incorporating the shortwave radiation flux, which has two empirical parameters. We apply it both with values of parameters obtained for Alpine glaciers and recalibrated on Juncal Norte. The model recalibrated against the correct energy balance simulations performs very well. The model parameters respond to the meteorological conditions typical of this climatic setting."}],"publisher":"Wiley","publication_status":"published","author":[{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","first_name":"Francesca","full_name":"Pellicciotti, Francesca","orcid":"0000-0002-5554-8087"},{"last_name":"Helbing","first_name":"Jakob","full_name":"Helbing, Jakob"},{"last_name":"Rivera","first_name":"Andrés","full_name":"Rivera, Andrés"},{"last_name":"Favier","first_name":"Vincent","full_name":"Favier, Vincent"},{"full_name":"Corripio, Javier","first_name":"Javier","last_name":"Corripio"},{"first_name":"José","full_name":"Araos, José","last_name":"Araos"},{"last_name":"Sicart","first_name":"Jean-Emmanuel","full_name":"Sicart, Jean-Emmanuel"},{"last_name":"Carenzo","full_name":"Carenzo, Marco","first_name":"Marco"}],"_id":"12656","extern":"1","day":"15","date_updated":"2024-10-14T12:00:17Z","month":"09","keyword":["Water Science and Technology"],"oa_version":"None","article_type":"original"},{"issue":"5","year":"2008","type":"journal_article","publication":"Current Biology","title":"Response properties of motion sensitive visual interneurons in the Lobula plate of Drosophila melanogaster","quality_controlled":0,"day":"11","author":[{"first_name":"Maximilian A","full_name":"Maximilian Jösch","orcid":"0000-0002-3937-1330","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","last_name":"Jösch"},{"last_name":"Plett","full_name":"Plett, Johannes","first_name":"Johannes"},{"full_name":"Borst, Alexander","first_name":"Alexander","last_name":"Borst"},{"last_name":"Reiff","first_name":"Dierk","full_name":"Reiff, Dierk F"}],"_id":"1296","publication_status":"published","publisher":"Cell Press","date_created":"2018-12-11T11:51:13Z","extern":1,"doi":"10.1016/j.cub.2008.02.022","status":"public","volume":18,"abstract":[{"text":"The crystalline-like structure of the optic lobes of the fruit fly Drosophila melanogaster has made them a model system for the study of neuronal cell-fate determination, axonal path finding, and target selection. For functional studies, however, the small size of the constituting visual interneurons has so far presented a formidable barrier. We have overcome this problem by establishing in vivo whole-cell recordings [1] from genetically targeted visual interneurons of Drosophila. Here, we describe the response properties of six motion-sensitive large-field neurons in the lobula plate that form a network consisting of individually identifiable, directionally selective cells most sensitive to vertical image motion (VS cells [2, 3]). Individual VS cell responses to visual motion stimuli exhibit all the characteristics that are indicative of presynaptic input from elementary motion detectors of the correlation type [4, 5]. Different VS cells possess distinct receptive fields that are arranged sequentially along the eye's azimuth, corresponding to their characteristic cellular morphology and position within the retinotopically organized lobula plate. In addition, lateral connections between individual VS cells cause strongly overlapping receptive fields that are wider than expected from their dendritic input. Our results suggest that motion vision in different dipteran fly species is accomplished in similar circuitries and according to common algorithmic rules. The underlying neural mechanisms of population coding within the VS cell network and of elementary motion detection, respectively, can now be analyzed by the combination of electrophysiology and genetic intervention in Drosophila.","lang":"eng"}],"citation":{"ieee":"M. A. Jösch, J. Plett, A. Borst, and D. Reiff, “Response properties of motion sensitive visual interneurons in the Lobula plate of Drosophila melanogaster,” <i>Current Biology</i>, vol. 18, no. 5. Cell Press, pp. 368–374, 2008.","apa":"Jösch, M. A., Plett, J., Borst, A., &#38; Reiff, D. (2008). Response properties of motion sensitive visual interneurons in the Lobula plate of Drosophila melanogaster. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2008.02.022\">https://doi.org/10.1016/j.cub.2008.02.022</a>","chicago":"Jösch, Maximilian A, Johannes Plett, Alexander Borst, and Dierk Reiff. “Response Properties of Motion Sensitive Visual Interneurons in the Lobula Plate of Drosophila Melanogaster.” <i>Current Biology</i>. Cell Press, 2008. <a href=\"https://doi.org/10.1016/j.cub.2008.02.022\">https://doi.org/10.1016/j.cub.2008.02.022</a>.","ista":"Jösch MA, Plett J, Borst A, Reiff D. 2008. Response properties of motion sensitive visual interneurons in the Lobula plate of Drosophila melanogaster. Current Biology. 18(5), 368–374.","short":"M.A. Jösch, J. Plett, A. Borst, D. Reiff, Current Biology 18 (2008) 368–374.","ama":"Jösch MA, Plett J, Borst A, Reiff D. Response properties of motion sensitive visual interneurons in the Lobula plate of Drosophila melanogaster. <i>Current Biology</i>. 2008;18(5):368-374. doi:<a href=\"https://doi.org/10.1016/j.cub.2008.02.022\">10.1016/j.cub.2008.02.022</a>","mla":"Jösch, Maximilian A., et al. “Response Properties of Motion Sensitive Visual Interneurons in the Lobula Plate of Drosophila Melanogaster.” <i>Current Biology</i>, vol. 18, no. 5, Cell Press, 2008, pp. 368–74, doi:<a href=\"https://doi.org/10.1016/j.cub.2008.02.022\">10.1016/j.cub.2008.02.022</a>."},"month":"03","intvolume":"        18","publist_id":"5973","date_updated":"2021-01-12T06:49:42Z","acknowledgement":"This work was supported by the Max-Planck-Society and by a Human Frontier Science Program (HFSP) grant to K. Ito, A.B., and B. Nelson.","date_published":"2008-03-11T00:00:00Z","page":"368 - 374"},{"abstract":[{"lang":"eng","text":"We consider the linear stochastic Cauchy problem dX (t) =AX (t) dt +B dWH (t), t≥ 0, where A generates a C0-semigroup on a Banach space E, WH is a cylindrical Brownian motion over a Hilbert space H, and B: H → E is a bounded operator. Assuming the existence of a unique minimal invariant measure μ∞, let Lp denote the realization of the Ornstein-Uhlenbeck operator associated with this problem in Lp (E, μ∞). Under suitable assumptions concerning the invariance of the range of B under the semigroup generated by A, we prove the following domain inclusions, valid for 1 &lt; p ≤ 2: Image omitted. Here WHk, p (E, μinfin; denotes the kth order Sobolev space of functions with Fréchet derivatives up to order k in the direction of H. No symmetry assumptions are made on L p."}],"volume":11,"doi":"10.1142/S0219025708003245","status":"public","citation":{"ieee":"J. Maas and J. Van Neerven, “On the domain of non-symmetric Ornstein-Uhlenbeck operators in banach spaces,” <i>Infinite Dimensional Analysis, Quantum Probability and Related Topics</i>, vol. 11, no. 4. World Scientific Publishing, pp. 603–626, 2008.","apa":"Maas, J., &#38; Van Neerven, J. (2008). On the domain of non-symmetric Ornstein-Uhlenbeck operators in banach spaces. <i>Infinite Dimensional Analysis, Quantum Probability and Related Topics</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0219025708003245\">https://doi.org/10.1142/S0219025708003245</a>","chicago":"Maas, Jan, and Jan Van Neerven. “On the Domain of Non-Symmetric Ornstein-Uhlenbeck Operators in Banach Spaces.” <i>Infinite Dimensional Analysis, Quantum Probability and Related Topics</i>. World Scientific Publishing, 2008. <a href=\"https://doi.org/10.1142/S0219025708003245\">https://doi.org/10.1142/S0219025708003245</a>.","ista":"Maas J, Van Neerven J. 2008. On the domain of non-symmetric Ornstein-Uhlenbeck operators in banach spaces. Infinite Dimensional Analysis, Quantum Probability and Related Topics. 11(4), 603–626.","short":"J. Maas, J. Van Neerven, Infinite Dimensional Analysis, Quantum Probability and Related Topics 11 (2008) 603–626.","ama":"Maas J, Van Neerven J. On the domain of non-symmetric Ornstein-Uhlenbeck operators in banach spaces. <i>Infinite Dimensional Analysis, Quantum Probability and Related Topics</i>. 2008;11(4):603-626. doi:<a href=\"https://doi.org/10.1142/S0219025708003245\">10.1142/S0219025708003245</a>","mla":"Maas, Jan, and Jan Van Neerven. “On the Domain of Non-Symmetric Ornstein-Uhlenbeck Operators in Banach Spaces.” <i>Infinite Dimensional Analysis, Quantum Probability and Related Topics</i>, vol. 11, no. 4, World Scientific Publishing, 2008, pp. 603–26, doi:<a href=\"https://doi.org/10.1142/S0219025708003245\">10.1142/S0219025708003245</a>."},"day":"04","quality_controlled":0,"extern":1,"_id":"2120","publication_status":"published","author":[{"first_name":"Jan","full_name":"Jan Maas","orcid":"0000-0002-0845-1338","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","last_name":"Maas"},{"last_name":"Van Neerven","first_name":"Jan","full_name":"van Neerven, Jan M"}],"date_created":"2018-12-11T11:55:50Z","publisher":"World Scientific Publishing","title":"On the domain of non-symmetric Ornstein-Uhlenbeck operators in banach spaces","publication":"Infinite Dimensional Analysis, Quantum Probability and Related Topics","year":"2008","issue":"4","type":"journal_article","acknowledgement":"The authors are supported by the ‘VIDI subsidie’ 639.032.201 of the Netherlands Organization for Scientific Research (NWO) and by the Research Training Network HPRN-CT-2002-00281.","date_published":"2008-12-04T00:00:00Z","page":"603 - 626","main_file_link":[{"url":"http://repository.tudelft.nl/view/ir/uuid:c8eca915-d38b-4827-a4d9-e89baabb43a6/","open_access":"1"}],"intvolume":"        11","month":"12","date_updated":"2021-01-12T06:55:26Z","publist_id":"4914","oa":1},{"oa":1,"date_published":"2008-04-07T00:00:00Z","acknowledgement":"Research supported by ARC Discovery Grant dp0558539. 2research supported by VIDI subsidy 639.032.201 and VICI subsidy 639.033.604 of the Netherlands organisation for scientific research (nwo). ","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0709.2021"}],"page":"151 - 164","intvolume":"        13","month":"04","date_updated":"2021-01-12T06:55:26Z","publist_id":"4915","title":"A Clark-Ocone formula in UMD Banach spaces","publication":"Electronic Communications in Probability","year":"2008","type":"journal_article","volume":13,"abstract":[{"text":"Let H be a separable real Hubert space and let double struck F sign = (ℱt)t∈[0,T] be the augmented filtration generated by an H-cylindrical Brownian motion (WH(t))t∈[0,T] on a probability space (Ω, ℱ ℙ). We prove that if E is a UMD Banach space, 1 ≤ p &lt; ∞, and F ∈ double struck D sign1,p(Ω E) is ℱT-measurable, then F = double struck E sign(F) + ∫0T Pdouble struck F sign(DF) dW H, where D is the Malliavin derivative of F and P double struck F sign is the projection onto the F-adapted elements in a suitable Banach space of Lp-stochastically integrable ℒ(H, E)-valued processes.","lang":"eng"}],"status":"public","citation":{"ama":"Van Neerven J, Maas J. A Clark-Ocone formula in UMD Banach spaces. <i>Electronic Communications in Probability</i>. 2008;13:151-164.","mla":"Van Neerven, Jan, and Jan Maas. “A Clark-Ocone Formula in UMD Banach Spaces.” <i>Electronic Communications in Probability</i>, vol. 13, Institute of Mathematical Statistics, 2008, pp. 151–64.","short":"J. Van Neerven, J. Maas, Electronic Communications in Probability 13 (2008) 151–164.","ista":"Van Neerven J, Maas J. 2008. A Clark-Ocone formula in UMD Banach spaces. Electronic Communications in Probability. 13, 151–164.","chicago":"Van Neerven, Jan, and Jan Maas. “A Clark-Ocone Formula in UMD Banach Spaces.” <i>Electronic Communications in Probability</i>. Institute of Mathematical Statistics, 2008.","ieee":"J. Van Neerven and J. Maas, “A Clark-Ocone formula in UMD Banach spaces,” <i>Electronic Communications in Probability</i>, vol. 13. Institute of Mathematical Statistics, pp. 151–164, 2008.","apa":"Van Neerven, J., &#38; Maas, J. (2008). A Clark-Ocone formula in UMD Banach spaces. <i>Electronic Communications in Probability</i>. Institute of Mathematical Statistics."},"day":"07","quality_controlled":0,"extern":1,"_id":"2121","publication_status":"published","date_created":"2018-12-11T11:55:50Z","publisher":"Institute of Mathematical Statistics","author":[{"last_name":"Van Neerven","first_name":"Jan","full_name":"van Neerven, Jan M"},{"id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","last_name":"Maas","full_name":"Jan Maas","orcid":"0000-0002-0845-1338","first_name":"Jan"}]},{"type":"journal_article","year":"2008","issue":"2","title":"An analytic model of rotationally inelastic collisions of polar molecules in electric fields","publication":"Journal of Chemical Physics","day":"01","quality_controlled":0,"extern":1,"publication_status":"published","_id":"2146","publisher":"American Institute of Physics","date_created":"2018-12-11T11:55:58Z","author":[{"full_name":"Mikhail Lemeshko","orcid":"0000-0002-6990-7802","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko"},{"last_name":"Friedrich","full_name":"Friedrich, Břetislav","first_name":"Břetislav"}],"volume":129,"abstract":[{"text":"We present an analytic model of thermal state-to-state rotationally inelastic collisions of polar molecules in electric fields. The model is based on the Fraunhofer scattering of matter waves and requires Legendre moments characterizing the “shape” of the target in the body-fixed frame as its input. The electric field orients the target in the space-fixed frame and thereby effects a striking alteration of the dynamical observables: both the phase and amplitude of the oscillations in the partial differential cross sections undergo characteristic field-dependent changes that transgress into the partial integral cross sections. As the cross sections can be evaluated for a field applied parallel or perpendicular to the relative velocity, the model also offers predictions about steric asymmetry. We exemplify the field-dependent quantum collision dynamics with the behavior of the Ne–OCS(Σ1) and Ar–NO(Π2) systems. A comparison with the close-coupling calculations available for the latter system [Chem. Phys. Lett.313, 491 (1999)] demonstrates the model’s ability to qualitatively explain the field dependence of all the scattering features observed.","lang":"eng"}],"status":"public","doi":"10.1063/1.2948392","citation":{"apa":"Lemeshko, M., &#38; Friedrich, B. (2008). An analytic model of rotationally inelastic collisions of polar molecules in electric fields. <i>Journal of Chemical Physics</i>. American Institute of Physics. <a href=\"https://doi.org/10.1063/1.2948392\">https://doi.org/10.1063/1.2948392</a>","ieee":"M. Lemeshko and B. Friedrich, “An analytic model of rotationally inelastic collisions of polar molecules in electric fields,” <i>Journal of Chemical Physics</i>, vol. 129, no. 2. American Institute of Physics, 2008.","chicago":"Lemeshko, Mikhail, and Břetislav Friedrich. “An Analytic Model of Rotationally Inelastic Collisions of Polar Molecules in Electric Fields.” <i>Journal of Chemical Physics</i>. American Institute of Physics, 2008. <a href=\"https://doi.org/10.1063/1.2948392\">https://doi.org/10.1063/1.2948392</a>.","ista":"Lemeshko M, Friedrich B. 2008. An analytic model of rotationally inelastic collisions of polar molecules in electric fields. Journal of Chemical Physics. 129(2).","short":"M. Lemeshko, B. Friedrich, Journal of Chemical Physics 129 (2008).","mla":"Lemeshko, Mikhail, and Břetislav Friedrich. “An Analytic Model of Rotationally Inelastic Collisions of Polar Molecules in Electric Fields.” <i>Journal of Chemical Physics</i>, vol. 129, no. 2, American Institute of Physics, 2008, doi:<a href=\"https://doi.org/10.1063/1.2948392\">10.1063/1.2948392</a>.","ama":"Lemeshko M, Friedrich B. An analytic model of rotationally inelastic collisions of polar molecules in electric fields. <i>Journal of Chemical Physics</i>. 2008;129(2). doi:<a href=\"https://doi.org/10.1063/1.2948392\">10.1063/1.2948392</a>"},"oa":1,"intvolume":"       129","month":"07","date_updated":"2021-01-12T06:55:35Z","publist_id":"4878","date_published":"2008-07-01T00:00:00Z","main_file_link":[{"url":"http://arxiv.org/abs/0804.3318","open_access":"1"}]},{"intvolume":"       102","month":"10","date_updated":"2020-07-14T12:45:29Z","publist_id":"4877","date_published":"2008-10-01T00:00:00Z","page":"880 - 883","year":"2008","issue":"10","type":"review","title":"Kvantový Zenonův jev aneb co nesejde z očí, nezestárne","publication":"Chemicke Listy","day":"01","quality_controlled":0,"extern":1,"publisher":"Czech Society of Chemical Engineering","_id":"2147","author":[{"first_name":"Mikhail","full_name":"Mikhail Lemeshko","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko"},{"first_name":"Břetislav","full_name":"Friedrich, Břetislav","last_name":"Friedrich"}],"date_created":"2018-12-11T11:55:59Z","publication_status":"published","abstract":[{"text":"We present the physics of the quantum Zeno effect, whose gist is often expressed by invoking the adage &quot;a watched pot never boils&quot;. We review aspects of the theoretical and experimental work done on the effect since its inception in 1977, and mention some applications. We dedicate the article - with our very best wishes - to Rudolf Zahradnik at the occasion of his great jubilee. Perhaps Rudolf's lasting youthfulness and freshness are due to that he himself had been frequently observed throughout his life: until the political turn-around in 1989 by those who wished, by their surveillance, to prevent Rudolf from spoiling the youth by his personal culture and his passion for science and things beautiful and useful in general. This attempt had failed. Out of gratitude, the youth has infected Rudolf with its youthfulness. Chronically. Since 1989, Rudolf has been closely watched by the public at large. For the same traits of his as before, but with the opposite goal and for the benefit of all generations. We relish keeping him in sight...","lang":"eng"}],"volume":102,"status":"public","citation":{"chicago":"Lemeshko, Mikhail, and Břetislav Friedrich. “Kvantový Zenonův Jev Aneb Co Nesejde z Očí, Nezestárne.” <i>Chemicke Listy</i>. Czech Society of Chemical Engineering, 2008.","apa":"Lemeshko, M., &#38; Friedrich, B. (2008). Kvantový Zenonův jev aneb co nesejde z očí, nezestárne. <i>Chemicke Listy</i>. Czech Society of Chemical Engineering.","ieee":"M. Lemeshko and B. Friedrich, “Kvantový Zenonův jev aneb co nesejde z očí, nezestárne,” <i>Chemicke Listy</i>, vol. 102, no. 10. Czech Society of Chemical Engineering, pp. 880–883, 2008.","mla":"Lemeshko, Mikhail, and Břetislav Friedrich. “Kvantový Zenonův Jev Aneb Co Nesejde z Očí, Nezestárne.” <i>Chemicke Listy</i>, vol. 102, no. 10, Czech Society of Chemical Engineering, 2008, pp. 880–83.","ama":"Lemeshko M, Friedrich B. Kvantový Zenonův jev aneb co nesejde z očí, nezestárne. <i>Chemicke Listy</i>. 2008;102(10):880-883.","short":"M. Lemeshko, B. Friedrich, Chemicke Listy 102 (2008) 880–883.","ista":"Lemeshko M, Friedrich B. 2008. Kvantový Zenonův jev aneb co nesejde z očí, nezestárne. Chemicke Listy. 102(10), 880–883."}},{"page":"667 - 681","date_published":"2008-04-01T00:00:00Z","date_updated":"2021-01-12T06:55:36Z","publist_id":"4876","intvolume":"        72","month":"04","title":"In situ X-ray absorption spectroscopy measurement of vapour-brine fractionation of antimony at hydrothermal conditions","publication":"Mineralogical Magazine","type":"journal_article","year":"2008","issue":"2","citation":{"short":"G. Pokrovski, J. Roux, J. Hazemann, A. Borisova, A. Gonchar, M. Lemeshko, Mineralogical Magazine 72 (2008) 667–681.","ista":"Pokrovski G, Roux J, Hazemann J, Borisova A, Gonchar A, Lemeshko M. 2008. In situ X-ray absorption spectroscopy measurement of vapour-brine fractionation of antimony at hydrothermal conditions. Mineralogical Magazine. 72(2), 667–681.","mla":"Pokrovski, Gleb, et al. “In Situ X-Ray Absorption Spectroscopy Measurement of Vapour-Brine Fractionation of Antimony at Hydrothermal Conditions.” <i>Mineralogical Magazine</i>, vol. 72, no. 2, Mineralogical Society, 2008, pp. 667–81, doi:<a href=\"https://doi.org/10.1180/minmag.2008.072.2.667 \">10.1180/minmag.2008.072.2.667 </a>.","ama":"Pokrovski G, Roux J, Hazemann J, Borisova A, Gonchar A, Lemeshko M. In situ X-ray absorption spectroscopy measurement of vapour-brine fractionation of antimony at hydrothermal conditions. <i>Mineralogical Magazine</i>. 2008;72(2):667-681. doi:<a href=\"https://doi.org/10.1180/minmag.2008.072.2.667 \">10.1180/minmag.2008.072.2.667 </a>","apa":"Pokrovski, G., Roux, J., Hazemann, J., Borisova, A., Gonchar, A., &#38; Lemeshko, M. (2008). In situ X-ray absorption spectroscopy measurement of vapour-brine fractionation of antimony at hydrothermal conditions. <i>Mineralogical Magazine</i>. Mineralogical Society. <a href=\"https://doi.org/10.1180/minmag.2008.072.2.667 \">https://doi.org/10.1180/minmag.2008.072.2.667 </a>","ieee":"G. Pokrovski, J. Roux, J. Hazemann, A. Borisova, A. Gonchar, and M. Lemeshko, “In situ X-ray absorption spectroscopy measurement of vapour-brine fractionation of antimony at hydrothermal conditions,” <i>Mineralogical Magazine</i>, vol. 72, no. 2. Mineralogical Society, pp. 667–681, 2008.","chicago":"Pokrovski, Gleb, Jacques Roux, Jean Hazemann, Anastassia Borisova, Anastasia Gonchar, and Mikhail Lemeshko. “In Situ X-Ray Absorption Spectroscopy Measurement of Vapour-Brine Fractionation of Antimony at Hydrothermal Conditions.” <i>Mineralogical Magazine</i>. Mineralogical Society, 2008. <a href=\"https://doi.org/10.1180/minmag.2008.072.2.667 \">https://doi.org/10.1180/minmag.2008.072.2.667 </a>."},"abstract":[{"text":"Despite the growing geological evidence that fluid boiling and vapour-liquid separation affect the distribution of metals in magmatic-hydrothermal systems significantly, there are few experimental data on the chemical status and partitioning of metals in the vapour and liquid phases. Here we report on an in situ measurement, using X-ray absorption fine structure (XAFS) spectroscopy, of antimony speciation and partitioning in the system Sb2O3-H2O-NaCl-HCl at 400°C and pressures 270–300 bar corresponding to the vapour-liquid equilibrium. Experiments were performed using a spectroscopic cell which allows simultaneous determination of the total concentration and atomic environment of the absorbing element (Sb) in each phase. Results show that quantitative vapour-brine separation of a supercritical aqueous salt fluid can be achieved by a controlled decompression and monitoring the X-ray absorbance of the fluid phase. Antimony concentrations in equilibrium with Sb2O3 (cubic, senarmontite) in the coexisting vapour and liquid phases and corresponding SbIII vapour-liquid partitioning coefficients are in agreement with recent data obtained using batch-reactor solubility techniques. The XAFS spectra analysis shows that hydroxy-chloride complexes, probably Sb(OH)2Cl0, are dominant both in the vapour and liquid phase in a salt-water system at acidic conditions. This first in situ XAFS study of element fractionation between coexisting volatile and dense phases opens new possibilities for systematic investigations of vapour-brine and fluid-melt immiscibility phenomena, avoiding many experimental artifacts common in less direct techniques.","lang":"eng"}],"volume":72,"doi":"10.1180/minmag.2008.072.2.667 ","status":"public","extern":1,"date_created":"2018-12-11T11:55:59Z","_id":"2148","publication_status":"published","publisher":"Mineralogical Society","author":[{"last_name":"Pokrovski","full_name":"Pokrovski, Gleb S","first_name":"Gleb"},{"last_name":"Roux","full_name":"Roux, Jacques L","first_name":"Jacques"},{"first_name":"Jean","full_name":"Hazemann, Jean L","last_name":"Hazemann"},{"last_name":"Borisova","full_name":"Borisova, Anastassia Y","first_name":"Anastassia"},{"first_name":"Anastasia","full_name":"Gonchar, Anastasia A","last_name":"Gonchar"},{"orcid":"0000-0002-6990-7802","full_name":"Mikhail Lemeshko","first_name":"Mikhail","last_name":"Lemeshko","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"}],"day":"01","quality_controlled":0},{"oa_version":"None","article_type":"original","OA_type":"closed access","date_updated":"2026-04-15T12:53:52Z","month":"10","ddc":["530"],"doi":"10.1007/s00542-008-0565-8","article_processing_charge":"No","abstract":[{"lang":"eng","text":"The possibility to fill cavities of finite geometry could be described using an analytical model of the hot-embossing process of viscoelastic polymers. This model is based on the volume conservation during the forming process which allows to predict data concerning the geometrical evolution of the material on one hand, and on the other hand the filling time of cavities in the mould. A particular attention was drawn on the necessary time to fill the cavities depending on their shape or a scale factor for a given cavity shape."}],"publisher":"Springer Nature","author":[{"last_name":"Sahli","full_name":"Sahli, M.","first_name":"M."},{"full_name":"Roques-Carmes, Charles","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","last_name":"Roques-Carmes"},{"first_name":"C.","full_name":"Khan Malek, C.","last_name":"Khan Malek"},{"last_name":"Gelin","full_name":"Gelin, J. C.","first_name":"J. C."}],"_id":"21512","publication_status":"published","extern":"1","day":"01","publication_identifier":{"eissn":["1432-1858"],"issn":["0946-7076"]},"page":"1545-1551","date_published":"2008-10-01T00:00:00Z","intvolume":"        14","language":[{"iso":"eng"}],"publication":"Microsystem Technologies","title":"Modelling of the filling of micro-cavities of finite geometry by amorphous polymers using hot-embossing","type":"journal_article","year":"2008","citation":{"chicago":"Sahli, M., Charles Roques-Carmes, C. Khan Malek, and J. C. Gelin. “Modelling of the Filling of Micro-Cavities of Finite Geometry by Amorphous Polymers Using Hot-Embossing.” <i>Microsystem Technologies</i>. Springer Nature, 2008. <a href=\"https://doi.org/10.1007/s00542-008-0565-8\">https://doi.org/10.1007/s00542-008-0565-8</a>.","apa":"Sahli, M., Roques-Carmes, C., Khan Malek, C., &#38; Gelin, J. C. (2008). Modelling of the filling of micro-cavities of finite geometry by amorphous polymers using hot-embossing. <i>Microsystem Technologies</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00542-008-0565-8\">https://doi.org/10.1007/s00542-008-0565-8</a>","ieee":"M. Sahli, C. Roques-Carmes, C. Khan Malek, and J. C. Gelin, “Modelling of the filling of micro-cavities of finite geometry by amorphous polymers using hot-embossing,” <i>Microsystem Technologies</i>, vol. 14. Springer Nature, pp. 1545–1551, 2008.","mla":"Sahli, M., et al. “Modelling of the Filling of Micro-Cavities of Finite Geometry by Amorphous Polymers Using Hot-Embossing.” <i>Microsystem Technologies</i>, vol. 14, Springer Nature, 2008, pp. 1545–51, doi:<a href=\"https://doi.org/10.1007/s00542-008-0565-8\">10.1007/s00542-008-0565-8</a>.","ama":"Sahli M, Roques-Carmes C, Khan Malek C, Gelin JC. Modelling of the filling of micro-cavities of finite geometry by amorphous polymers using hot-embossing. <i>Microsystem Technologies</i>. 2008;14:1545-1551. doi:<a href=\"https://doi.org/10.1007/s00542-008-0565-8\">10.1007/s00542-008-0565-8</a>","ista":"Sahli M, Roques-Carmes C, Khan Malek C, Gelin JC. 2008. Modelling of the filling of micro-cavities of finite geometry by amorphous polymers using hot-embossing. Microsystem Technologies. 14, 1545–1551.","short":"M. Sahli, C. Roques-Carmes, C. Khan Malek, J.C. Gelin, Microsystem Technologies 14 (2008) 1545–1551."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","volume":14,"date_created":"2026-03-30T12:22:47Z","quality_controlled":"1","scopus_import":"1"},{"page":"1635-1639","date_published":"2008-10-09T00:00:00Z","intvolume":"         4","publication_identifier":{"issn":["1613-6810"],"eissn":["1613-6829"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"short":"Y. Wei, R. Klajn, A.O. Pinchuk, B.A. Grzybowski, Small 4 (2008) 1635–1639.","ista":"Wei Y, Klajn R, Pinchuk AO, Grzybowski BA. 2008. Synthesis, shape control, and optical properties of hybrid Au/Fe3O4 “nanoflowers”. Small. 4(10), 1635–1639.","mla":"Wei, Yanhu, et al. “Synthesis, Shape Control, and Optical Properties of Hybrid Au/Fe3O4 ‘Nanoflowers.’” <i>Small</i>, vol. 4, no. 10, Wiley, 2008, pp. 1635–39, doi:<a href=\"https://doi.org/10.1002/smll.200800511\">10.1002/smll.200800511</a>.","ama":"Wei Y, Klajn R, Pinchuk AO, Grzybowski BA. Synthesis, shape control, and optical properties of hybrid Au/Fe3O4 “nanoflowers.” <i>Small</i>. 2008;4(10):1635-1639. doi:<a href=\"https://doi.org/10.1002/smll.200800511\">10.1002/smll.200800511</a>","apa":"Wei, Y., Klajn, R., Pinchuk, A. O., &#38; Grzybowski, B. A. (2008). Synthesis, shape control, and optical properties of hybrid Au/Fe3O4 “nanoflowers.” <i>Small</i>. Wiley. <a href=\"https://doi.org/10.1002/smll.200800511\">https://doi.org/10.1002/smll.200800511</a>","ieee":"Y. Wei, R. Klajn, A. O. Pinchuk, and B. A. Grzybowski, “Synthesis, shape control, and optical properties of hybrid Au/Fe3O4 ‘nanoflowers,’” <i>Small</i>, vol. 4, no. 10. Wiley, pp. 1635–1639, 2008.","chicago":"Wei, Yanhu, Rafal Klajn, Anatoliy O. Pinchuk, and Bartosz A. Grzybowski. “Synthesis, Shape Control, and Optical Properties of Hybrid Au/Fe3O4 ‘Nanoflowers.’” <i>Small</i>. Wiley, 2008. <a href=\"https://doi.org/10.1002/smll.200800511\">https://doi.org/10.1002/smll.200800511</a>."},"status":"public","volume":4,"date_created":"2023-08-01T10:30:42Z","scopus_import":"1","quality_controlled":"1","language":[{"iso":"eng"}],"publication":"Small","title":"Synthesis, shape control, and optical properties of hybrid Au/Fe3O4 “nanoflowers”","year":"2008","type":"journal_article","issue":"10","pmid":1,"date_updated":"2023-08-08T11:14:50Z","month":"10","keyword":["Biomaterials","Biotechnology","General Materials Science","General Chemistry"],"oa_version":"None","article_type":"original","doi":"10.1002/smll.200800511","abstract":[{"lang":"eng","text":"Make like a leaf: The synthesis and characterization of a family of “flowerlike” Au/Fe3O4 nanoparticles is described, whereby Fe3O4 “leaves” adhere to a gold core (see image). The size and numbers of iron oxide domains can be adjusted flexibly by changing the proportion of the starting materials and the reaction time."}],"article_processing_charge":"No","_id":"13422","publication_status":"published","author":[{"first_name":"Yanhu","full_name":"Wei, Yanhu","last_name":"Wei"},{"first_name":"Rafal","full_name":"Klajn, Rafal","last_name":"Klajn","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b"},{"full_name":"Pinchuk, Anatoliy O.","first_name":"Anatoliy O.","last_name":"Pinchuk"},{"last_name":"Grzybowski","first_name":"Bartosz A.","full_name":"Grzybowski, Bartosz A."}],"publisher":"Wiley","external_id":{"pmid":["18636405"]},"extern":"1","day":"09"},{"doi":"10.1002/adfm.200800293","article_processing_charge":"No","abstract":[{"text":"Supraspheres (SS) composed of hundreds to thousands of metal nanoparticles (NPs) and crosslinked by dithiol linkers are assembled into larger structures, which are subsequently converted into nanoporous metals (NMs). Conversion is achieved by heating which removes organic molecules stabilizing the NPs and allows for NP fusion. Heating of SS solutions leads to NMs of overall macroscopic dimensions; localized radiation using collimated electron beam is used to prepare metallized surface micropatterns. Depending on the composition of supraspherical precursors, nanoporous materials composed of up to three metals can be obtained. Strategies for controlling pore size and nanoscale surface roughness of these materials are discussed.","lang":"eng"}],"day":"23","author":[{"full_name":"Klajn, Rafal","first_name":"Rafal","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","last_name":"Klajn"},{"last_name":"Gray","first_name":"Timothy P.","full_name":"Gray, Timothy P."},{"last_name":"Wesson","first_name":"Paul J.","full_name":"Wesson, Paul J."},{"last_name":"Myers","full_name":"Myers, Benjamin D.","first_name":"Benjamin D."},{"full_name":"Dravid, Vinayak P.","first_name":"Vinayak P.","last_name":"Dravid"},{"last_name":"Smoukov","full_name":"Smoukov, Stoyan K.","first_name":"Stoyan K."},{"last_name":"Grzybowski","first_name":"Bartosz A.","full_name":"Grzybowski, Bartosz A."}],"publication_status":"published","_id":"13423","publisher":"Wiley","extern":"1","keyword":["Electrochemistry","Condensed Matter Physics","Biomaterials","Electronic","Optical and Magnetic Materials"],"oa_version":"None","article_type":"original","month":"09","date_updated":"2023-08-08T11:16:28Z","publication":"Advanced Functional Materials","title":"Bulk synthesis and surface patterning of nanoporous metals and alloys from supraspherical nanoparticle aggregates","language":[{"iso":"eng"}],"year":"2008","issue":"18","type":"journal_article","status":"public","volume":18,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"apa":"Klajn, R., Gray, T. P., Wesson, P. J., Myers, B. D., Dravid, V. P., Smoukov, S. K., &#38; Grzybowski, B. A. (2008). Bulk synthesis and surface patterning of nanoporous metals and alloys from supraspherical nanoparticle aggregates. <i>Advanced Functional Materials</i>. Wiley. <a href=\"https://doi.org/10.1002/adfm.200800293\">https://doi.org/10.1002/adfm.200800293</a>","ieee":"R. Klajn <i>et al.</i>, “Bulk synthesis and surface patterning of nanoporous metals and alloys from supraspherical nanoparticle aggregates,” <i>Advanced Functional Materials</i>, vol. 18, no. 18. Wiley, pp. 2763–2769, 2008.","chicago":"Klajn, Rafal, Timothy P. Gray, Paul J. Wesson, Benjamin D. Myers, Vinayak P. Dravid, Stoyan K. Smoukov, and Bartosz A. Grzybowski. “Bulk Synthesis and Surface Patterning of Nanoporous Metals and Alloys from Supraspherical Nanoparticle Aggregates.” <i>Advanced Functional Materials</i>. Wiley, 2008. <a href=\"https://doi.org/10.1002/adfm.200800293\">https://doi.org/10.1002/adfm.200800293</a>.","short":"R. Klajn, T.P. Gray, P.J. Wesson, B.D. Myers, V.P. Dravid, S.K. Smoukov, B.A. Grzybowski, Advanced Functional Materials 18 (2008) 2763–2769.","ista":"Klajn R, Gray TP, Wesson PJ, Myers BD, Dravid VP, Smoukov SK, Grzybowski BA. 2008. Bulk synthesis and surface patterning of nanoporous metals and alloys from supraspherical nanoparticle aggregates. Advanced Functional Materials. 18(18), 2763–2769.","mla":"Klajn, Rafal, et al. “Bulk Synthesis and Surface Patterning of Nanoporous Metals and Alloys from Supraspherical Nanoparticle Aggregates.” <i>Advanced Functional Materials</i>, vol. 18, no. 18, Wiley, 2008, pp. 2763–69, doi:<a href=\"https://doi.org/10.1002/adfm.200800293\">10.1002/adfm.200800293</a>.","ama":"Klajn R, Gray TP, Wesson PJ, et al. Bulk synthesis and surface patterning of nanoporous metals and alloys from supraspherical nanoparticle aggregates. <i>Advanced Functional Materials</i>. 2008;18(18):2763-2769. doi:<a href=\"https://doi.org/10.1002/adfm.200800293\">10.1002/adfm.200800293</a>"},"scopus_import":"1","quality_controlled":"1","date_created":"2023-08-01T10:30:57Z","publication_identifier":{"issn":["1616-301X"],"eissn":["1616-3028"]},"date_published":"2008-09-23T00:00:00Z","page":"2763-2769","intvolume":"        18"}]