---
OA_place: publisher
_id: '20991'
abstract:
- lang: eng
  text: "Rapid local adaptation to new environments is critical for species persistence,
    especially in introduced populations. The evolutionary success of these populations
    is fundamentally dictated by the organization of genetic variation—the genomic
    architecture—in the face of severe demographic constraints, such as the founder
    effects and genetic bottlenecks that frequently accompany colonization. A central
    question in evolutionary biology is whether rapid adaptation relies on major-effect
    loci, such as chromosomal inversions, or on many small-effect loci dispersed across
    the genome. Furthermore, the genomic architecture strongly influences the extent
    to which evolutionary outcomes are predictable. Using introduced populations of
    the marine snail, Littorina saxatilis, as a model, this thesis investigates how
    genetic variation and genomic structure drive adaptation following introduction.
    We employed a population genomics approach on experimentally and accidentally
    introduced populations to dissect the specific genomic features that underpin
    divergence in newly colonized environments.\r\n\r\nIn Chapter 2, we tested the
    predictability of local adaptation through an uncommon 30-year transplant experiment
    in nature. By distinguishing allele and chromosomal inversion frequency changes
    from neutral expectations, we found that evolutionary change was highly predictable
    at the macro-scale (phenotypes and chromosomal inversions), but less robust at
    the level of individual collinear loci. This result demonstrates that evolution
    can be predictable when a population possesses sufficient standing genetic variation
    (SGV), with chromosomal inversions acting as key integrated units that facilitate
    a rapid response to selection. Building on this, Chapter 3 applied whole-genome
    sequencing to three accidentally introduced populations (Venice, San Francisco,
    and Redwood City) to investigate their likely source and genomic patterns of divergence.
    We identified genomic regions of remarkable divergence potentially associated
    with local adaptation, and likely fuelled by SGV, while explicitly acknowledging
    the difficulty in disentangling selection signals from the genome-wide effects
    of demographic processes. Furthermore, we found that the divergence patterns relied
    extensively on the collinear genome in these introduced populations, and less
    clearly on the chromosomal inversions. This observation contrasts with local adaptation
    observed in the experimental system that relied on both collinear loci and highly
    selected chromosomal inversions, highlighting how demographic history and genomic
    architecture influence the detectable signature of local adaptation.\r\n\r\nA
    major limitation to conducting large-scale comparative evolutionary studies is
    the lack of data standardization, which prevents the integration of community
    knowledge and high-resolution environmental and genetic data. Chapter 4 addresses
    this by developing a community database for the Littorina system. This platform
    implements standardized protocols for the integration of diverse phenotypic and
    environmental data from multiple Littorina species. Likewise, the platform also
    centralizes the availability of associated genomic data through links to external
    repositories. This database represents a crucial tool to test complex, large-scale
    evolutionary hypotheses.\r\n\r\nCollectively, this thesis strongly reinforces
    the fundamental importance of SGV as the raw material for successful local adaptation,
    a conclusion supported by evidence in both experimental and accidental introductions.
    Furthermore, this work highlights the critical role of the genomic architecture—specifically
    chromosomal inversions—in driving the predictability and effectiveness of adaptive
    responses. Our findings underscore how the interplay between SGV and genomic architecture
    dictates the trajectory and detectability of evolution in colonizing populations,
    while simultaneously providing a necessary tool to advance comparative evolutionary
    genomics in emerging model organisms."
acknowledgement: "I acknowledge the funding agencies 1Norwegian Research Council RCN
  project 315287.\r\n2The FIASCO project \"Illuminating range shifts through evolutionary
  FIASCO: contrasting\r\nFaIling And Successful ColOnizations in replicated wild populations\",
  funded by the\r\nEuropean Union - Next Generation EU (Piano Nazionale di Ripresa
  e Resilienza - MUR\r\ncode: P202229JBC, CUP: C53D23007100001). 3Ecotypic formation
  in Littorina saxatilis\r\nin the Western Atlantic and comparisons across the North
  Atlantic. University of\r\nGothenburg Research Travel Grant, Tjarno Marine Laboratory,
  Sweden. $3023 (2018).\r\n4JIN project (Young Researchers, Spanish Ministry of Science,
  RTI2018-101274-J-I00)"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Diego Fernando
  full_name: Garcia Castillo, Diego Fernando
  id: ae681a14-dc74-11ea-a0a7-c6ef18161701
  last_name: Garcia Castillo
citation:
  ama: Garcia Castillo DF. The genomic architecture of local adaptation in introduced
    populations. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-20991">10.15479/AT-ISTA-20991</a>
  apa: Garcia Castillo, D. F. (2026). <i>The genomic architecture of local adaptation
    in introduced populations</i>. Institute of Science and Technology Austria. <a
    href="https://doi.org/10.15479/AT-ISTA-20991">https://doi.org/10.15479/AT-ISTA-20991</a>
  chicago: Garcia Castillo, Diego Fernando. “The Genomic Architecture of Local Adaptation
    in Introduced Populations.” Institute of Science and Technology Austria, 2026.
    <a href="https://doi.org/10.15479/AT-ISTA-20991">https://doi.org/10.15479/AT-ISTA-20991</a>.
  ieee: D. F. Garcia Castillo, “The genomic architecture of local adaptation in introduced
    populations,” Institute of Science and Technology Austria, 2026.
  ista: Garcia Castillo DF. 2026. The genomic architecture of local adaptation in
    introduced populations. Institute of Science and Technology Austria.
  mla: Garcia Castillo, Diego Fernando. <i>The Genomic Architecture of Local Adaptation
    in Introduced Populations</i>. Institute of Science and Technology Austria, 2026,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-20991">10.15479/AT-ISTA-20991</a>.
  short: D.F. Garcia Castillo, The Genomic Architecture of Local Adaptation in Introduced
    Populations, Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-01-16T09:47:59Z
date_published: 2026-01-16T00:00:00Z
date_updated: 2026-04-16T12:20:37Z
day: '16'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: NiBa
doi: 10.15479/AT-ISTA-20991
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  date_updated: 2026-01-16T12:25:13Z
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  date_updated: 2026-01-16T13:08:14Z
  description: Source code of the PostgreSQL database, front-end and back-end of the
    LittorinaDB web application developed as a product of the 4th chapter of the thesis.
  file_id: '20998'
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file_date_updated: 2026-01-16T13:08:59Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '01'
oa: 1
oa_version: Published Version
page: '199'
publication_identifier:
  isbn:
  - 978-3-99078-077-0
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18498'
    relation: research_data
    status: public
  - id: '18491'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
title: The genomic architecture of local adaptation in introduced populations
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21537'
abstract:
- lang: eng
  text: Nanophotonics has revolutionized the control of light-matter interactions
    in various fields of fundamental science and technology. In this work, we propose
    Implosion Fabrication (ImpFab) as a versatile nanophotonics fabrication platform
    providing the highest spatial resolution, material versatility, and full volumetric
    control. ImpFab uniquely combines top-down lithography with bottom-up nanoparticle
    assembly within a hydrogel scaffold, enabling precise control over optical material
    properties, such as refractive index, by adjusting printing parameters. We showcase
    the potential of ImpFab by fabricating three-dimensional photonic crystals and
    quasicrystals, as well as demonstrating optical structures with spatially modulated
    unit cell material properties. Our results highlight the potential of ImpFab in
    producing nanostructures with tailored optical functionalities, which are crucial
    for applications in sensing, imaging, and information processing, and opening
    new avenues in developing non-Hermitian photonic systems with spatially controlled
    gain and loss.
article_number: '145'
article_processing_charge: No
article_type: original
author:
- first_name: Yannick
  full_name: Salamin, Yannick
  last_name: Salamin
- first_name: Gaojie
  full_name: Yang, Gaojie
  last_name: Yang
- first_name: Brian
  full_name: Mills, Brian
  last_name: Mills
- first_name: André
  full_name: Grossi Fonseca, André
  last_name: Grossi Fonseca
- first_name: Charles
  full_name: Roques-Carmes, Charles
  id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
  last_name: Roques-Carmes
- first_name: Quansan
  full_name: Yang, Quansan
  last_name: Yang
- first_name: Justin
  full_name: Beroz, Justin
  last_name: Beroz
- first_name: Steven E.
  full_name: Kooi, Steven E.
  last_name: Kooi
- first_name: Marc
  full_name: de Miguel Comella, Marc
  last_name: de Miguel Comella
- first_name: Kiran
  full_name: Mak, Kiran
  last_name: Mak
- first_name: Sachin
  full_name: Vaidya, Sachin
  last_name: Vaidya
- first_name: Daniel
  full_name: Oran, Daniel
  last_name: Oran
- first_name: Corban
  full_name: Swain, Corban
  last_name: Swain
- first_name: Yi
  full_name: Sun, Yi
  last_name: Sun
- first_name: Shai
  full_name: Maayani, Shai
  last_name: Maayani
- first_name: Jamison
  full_name: Sloan, Jamison
  last_name: Sloan
- first_name: Amel
  full_name: Amin Elfadil Elawad, Amel
  last_name: Amin Elfadil Elawad
- first_name: Josue J.
  full_name: Lopez, Josue J.
  last_name: Lopez
- first_name: Edward S.
  full_name: Boyden, Edward S.
  last_name: Boyden
- first_name: Marin
  full_name: Soljačić, Marin
  last_name: Soljačić
citation:
  ama: 'Salamin Y, Yang G, Mills B, et al. Three-dimensional nanophotonics with spatially
    modulated optical properties. <i>Light: Science &#38; Applications</i>. 2026;15.
    doi:<a href="https://doi.org/10.1038/s41377-025-02166-5">10.1038/s41377-025-02166-5</a>'
  apa: 'Salamin, Y., Yang, G., Mills, B., Grossi Fonseca, A., Roques-Carmes, C., Yang,
    Q., … Soljačić, M. (2026). Three-dimensional nanophotonics with spatially modulated
    optical properties. <i>Light: Science &#38; Applications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41377-025-02166-5">https://doi.org/10.1038/s41377-025-02166-5</a>'
  chicago: 'Salamin, Yannick, Gaojie Yang, Brian Mills, André Grossi Fonseca, Charles
    Roques-Carmes, Quansan Yang, Justin Beroz, et al. “Three-Dimensional Nanophotonics
    with Spatially Modulated Optical Properties.” <i>Light: Science &#38; Applications</i>.
    Springer Nature, 2026. <a href="https://doi.org/10.1038/s41377-025-02166-5">https://doi.org/10.1038/s41377-025-02166-5</a>.'
  ieee: 'Y. Salamin <i>et al.</i>, “Three-dimensional nanophotonics with spatially
    modulated optical properties,” <i>Light: Science &#38; Applications</i>, vol.
    15. Springer Nature, 2026.'
  ista: 'Salamin Y, Yang G, Mills B, Grossi Fonseca A, Roques-Carmes C, Yang Q, Beroz
    J, Kooi SE, de Miguel Comella M, Mak K, Vaidya S, Oran D, Swain C, Sun Y, Maayani
    S, Sloan J, Amin Elfadil Elawad A, Lopez JJ, Boyden ES, Soljačić M. 2026. Three-dimensional
    nanophotonics with spatially modulated optical properties. Light: Science &#38;
    Applications. 15, 145.'
  mla: 'Salamin, Yannick, et al. “Three-Dimensional Nanophotonics with Spatially Modulated
    Optical Properties.” <i>Light: Science &#38; Applications</i>, vol. 15, 145, Springer
    Nature, 2026, doi:<a href="https://doi.org/10.1038/s41377-025-02166-5">10.1038/s41377-025-02166-5</a>.'
  short: 'Y. Salamin, G. Yang, B. Mills, A. Grossi Fonseca, C. Roques-Carmes, Q. Yang,
    J. Beroz, S.E. Kooi, M. de Miguel Comella, K. Mak, S. Vaidya, D. Oran, C. Swain,
    Y. Sun, S. Maayani, J. Sloan, A. Amin Elfadil Elawad, J.J. Lopez, E.S. Boyden,
    M. Soljačić, Light: Science &#38; Applications 15 (2026).'
date_created: 2026-03-30T12:22:47Z
date_published: 2026-03-03T00:00:00Z
date_updated: 2026-04-27T07:59:10Z
day: '03'
ddc:
- '530'
doi: 10.1038/s41377-025-02166-5
extern: '1'
external_id:
  pmid:
  - ' 41775693'
intvolume: '        15'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41377-025-02166-5
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: 'Light: Science & Applications'
publication_identifier:
  eissn:
  - 2047-7538
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Three-dimensional nanophotonics with spatially modulated optical properties
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 15
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21555'
abstract:
- lang: eng
  text: Spin-polarized electron beam sources enable studies of spin-dependent electric
    and magnetic effects at the nanoscale. We propose a method of creating spin-polarized
    electrons on an integrated photonics chip by laser-driven nanophotonic fields.
    A two-stage interaction separated by a free-space drift length is proposed, where
    the first stage and drift length introduces spin-dependent characteristics into
    the probability distribution of the electron wave function. The second stage uses
    an adjusted optical near field to rotate the spin states utilizing the spin-dependent
    wave-packet distribution to produce electrons with high ensemble average spin
    expectation values. This platform provides an integrated and compact method to
    generate spin-polarized electrons, implementable with millimeter scale chips and
    tabletop lasers.
article_number: '063802'
article_processing_charge: No
article_type: original
author:
- first_name: Clarisse
  full_name: Woodahl, Clarisse
  last_name: Woodahl
- first_name: Melanie
  full_name: Murillo, Melanie
  last_name: Murillo
- first_name: Charles
  full_name: Roques-Carmes, Charles
  id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
  last_name: Roques-Carmes
- first_name: Aviv
  full_name: Karnieli, Aviv
  last_name: Karnieli
- first_name: David A. B.
  full_name: Miller, David A. B.
  last_name: Miller
- first_name: Olav
  full_name: Solgaard, Olav
  last_name: Solgaard
citation:
  ama: Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O.
    On-chip laser-driven free-electron spin polarizer. <i>Physical Review Letters</i>.
    2026;136(6). doi:<a href="https://doi.org/10.1103/3c1m-d3hh">10.1103/3c1m-d3hh</a>
  apa: Woodahl, C., Murillo, M., Roques-Carmes, C., Karnieli, A., Miller, D. A. B.,
    &#38; Solgaard, O. (2026). On-chip laser-driven free-electron spin polarizer.
    <i>Physical Review Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/3c1m-d3hh">https://doi.org/10.1103/3c1m-d3hh</a>
  chicago: Woodahl, Clarisse, Melanie Murillo, Charles Roques-Carmes, Aviv Karnieli,
    David A. B. Miller, and Olav Solgaard. “On-Chip Laser-Driven Free-Electron Spin
    Polarizer.” <i>Physical Review Letters</i>. American Physical Society, 2026. <a
    href="https://doi.org/10.1103/3c1m-d3hh">https://doi.org/10.1103/3c1m-d3hh</a>.
  ieee: C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D. A. B. Miller, and
    O. Solgaard, “On-chip laser-driven free-electron spin polarizer,” <i>Physical
    Review Letters</i>, vol. 136, no. 6. American Physical Society, 2026.
  ista: Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O.
    2026. On-chip laser-driven free-electron spin polarizer. Physical Review Letters.
    136(6), 063802.
  mla: Woodahl, Clarisse, et al. “On-Chip Laser-Driven Free-Electron Spin Polarizer.”
    <i>Physical Review Letters</i>, vol. 136, no. 6, 063802, American Physical Society,
    2026, doi:<a href="https://doi.org/10.1103/3c1m-d3hh">10.1103/3c1m-d3hh</a>.
  short: C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D.A.B. Miller, O.
    Solgaard, Physical Review Letters 136 (2026).
date_created: 2026-03-30T12:22:47Z
date_published: 2026-02-12T00:00:00Z
date_updated: 2026-04-27T08:34:51Z
day: '12'
ddc:
- '530'
doi: 10.1103/3c1m-d3hh
extern: '1'
intvolume: '       136'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1103/3c1m-d3hh
month: '02'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: On-chip laser-driven free-electron spin polarizer
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21583'
abstract:
- lang: eng
  text: Non-Hermiticity naturally arises in physical systems that exchange energy
    with their environment. The presence of non-Hermiticity leads to many topological
    physics phenomena and device applications. In the non-Hermitian energy band theory,
    the foundation of these physics and applications, both energies and wave vectors
    take complex values. The energy bands thus become a Riemann surface, and such
    an energy-band Riemann surface underlies all important signatures of non-Hermitian
    topology. Despite a long history and recent theoretical interests, the energy-band
    Riemann surface has not been experimentally studied. Here, we provide a photonic
    observation of the energy-band Riemann surface of a non-Hermitian system. This
    is achieved by a tunable imaginary gauge transformation in photonic synthetic
    frequency dimensions. From measured topologies of the Riemann surface, we reveal
    the complex-energy winding, the open-boundary-condition spectrum, the generalized
    Brillouin zone, and the branch points. Our findings demonstrate a unified framework
    in the studies of diverse effects in non-Hermitian topological physics through
    an experimental observation of energy-band Riemann surfaces.
article_number: eaec8239
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Dali
  full_name: Cheng, Dali
  last_name: Cheng
- first_name: Heming
  full_name: Wang, Heming
  last_name: Wang
- first_name: Janet
  full_name: Zhong, Janet
  last_name: Zhong
- first_name: Eran
  full_name: Lustig, Eran
  last_name: Lustig
- first_name: Charles
  full_name: Roques-Carmes, Charles
  id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
  last_name: Roques-Carmes
- first_name: Shanhui
  full_name: Fan, Shanhui
  last_name: Fan
citation:
  ama: Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. Experimental observation
    of energy-band Riemann surface. <i>Science Advances</i>. 2026;12(12). doi:<a href="https://doi.org/10.1126/sciadv.aec8239">10.1126/sciadv.aec8239</a>
  apa: Cheng, D., Wang, H., Zhong, J., Lustig, E., Roques-Carmes, C., &#38; Fan, S.
    (2026). Experimental observation of energy-band Riemann surface. <i>Science Advances</i>.
    American Association for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.aec8239">https://doi.org/10.1126/sciadv.aec8239</a>
  chicago: Cheng, Dali, Heming Wang, Janet Zhong, Eran Lustig, Charles Roques-Carmes,
    and Shanhui Fan. “Experimental Observation of Energy-Band Riemann Surface.” <i>Science
    Advances</i>. American Association for the Advancement of Science, 2026. <a href="https://doi.org/10.1126/sciadv.aec8239">https://doi.org/10.1126/sciadv.aec8239</a>.
  ieee: D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, and S. Fan, “Experimental
    observation of energy-band Riemann surface,” <i>Science Advances</i>, vol. 12,
    no. 12. American Association for the Advancement of Science, 2026.
  ista: Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. 2026. Experimental
    observation of energy-band Riemann surface. Science Advances. 12(12), eaec8239.
  mla: Cheng, Dali, et al. “Experimental Observation of Energy-Band Riemann Surface.”
    <i>Science Advances</i>, vol. 12, no. 12, eaec8239, American Association for the
    Advancement of Science, 2026, doi:<a href="https://doi.org/10.1126/sciadv.aec8239">10.1126/sciadv.aec8239</a>.
  short: D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, S. Fan, Science
    Advances 12 (2026).
date_created: 2026-03-30T12:22:48Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-27T10:01:35Z
day: '18'
doi: 10.1126/sciadv.aec8239
extern: '1'
external_id:
  arxiv:
  - '2510.08819'
intvolume: '        12'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1126/sciadv.aec8239
month: '03'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_identifier:
  issn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental observation of energy-band Riemann surface
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21764'
abstract:
- lang: eng
  text: "Colloidal fluids can exhibit complex phase behavior and determining phase
    diagrams via experiments or computer simulations can be laborious. We demonstrate
    that the dispersion relation ω(k), obtained from dynamical density functional
    theory for the uniform density system, is a highly versatile tool for predicting
    where in the phase diagram complex crystals form. The sign of ω(k) determines
    whether density modes with wave number k grow or decay over time. We demonstrate
    the predictive power by investigating the complex phase behavior of particles
    interacting via core-shoulder pair potentials. With complementary Monte Carlo
    simulations, we show that regions of the phase diagram where ωðkÞ has one or several
    unstable (growing) wave numbers are also where crystalline phases occur. Going
    further, by tuning these\r\nunstable wave numbers via the interaction-potential
    and state-point parameters, we design systems with quasicrystals in the phase
    diagram. We identify a system with a certain shoulder range exhibiting at least
    ten different phases. Our general approach accelerates considerably the mapping
    of complex phase diagrams, crucial for the design of new materials."
acknowledgement: "The authors thank Ms. Katrin Muck for her guidance related to the
  use of HPC. The MC\r\ncomputer simulation results presented here were enabled via
  a generous share of CPU time, offered by the Vienna Scientific Cluster (VSC) under
  Project No. 71263. A. J. A. gratefully acknowledges support from the EPSRC under
  Grant No. EP/P015689/1. This research was funded in part by the Austrian Science
  Fund (FWF) [Grant DOI: 10.55776/PIN8759524], gratefully acknowledged by G. K ."
article_number: '148203'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Wassermair, Michael
  id: 23d132c4-4e98-11ef-b275-9e8d4cd8c917
  last_name: Wassermair
  orcid: 0009-0003-6339-4051
- first_name: Gerhard
  full_name: Kahl, Gerhard
  last_name: Kahl
- first_name: Roland
  full_name: Roth, Roland
  last_name: Roth
- first_name: Andrew J.
  full_name: Archer, Andrew J.
  last_name: Archer
citation:
  ama: Wassermair M, Kahl G, Roth R, Archer AJ. Navigating complex phase diagrams
    in soft matter systems. <i>Physical Review Letters</i>. 2026;136(14). doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>
  apa: Wassermair, M., Kahl, G., Roth, R., &#38; Archer, A. J. (2026). Navigating
    complex phase diagrams in soft matter systems. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>
  chicago: Wassermair, Michael, Gerhard Kahl, Roland Roth, and Andrew J. Archer. “Navigating
    Complex Phase Diagrams in Soft Matter Systems.” <i>Physical Review Letters</i>.
    American Physical Society, 2026. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>.
  ieee: M. Wassermair, G. Kahl, R. Roth, and A. J. Archer, “Navigating complex phase
    diagrams in soft matter systems,” <i>Physical Review Letters</i>, vol. 136, no.
    14. American Physical Society, 2026.
  ista: Wassermair M, Kahl G, Roth R, Archer AJ. 2026. Navigating complex phase diagrams
    in soft matter systems. Physical Review Letters. 136(14), 148203.
  mla: Wassermair, Michael, et al. “Navigating Complex Phase Diagrams in Soft Matter
    Systems.” <i>Physical Review Letters</i>, vol. 136, no. 14, 148203, American Physical
    Society, 2026, doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>.
  short: M. Wassermair, G. Kahl, R. Roth, A.J. Archer, Physical Review Letters 136
    (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-04-28T07:03:48Z
day: '10'
ddc:
- '530'
department:
- _id: AnSa
- _id: GradSch
doi: 10.1103/nbvt-fgjy
external_id:
  arxiv:
  - '2603.18918'
file:
- access_level: open_access
  checksum: 8ffb139122a185fcddbe6a9c901a287c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T06:58:40Z
  date_updated: 2026-04-28T06:58:40Z
  file_id: '21769'
  file_name: 2026_PhysicalReviewLetters_Wassermair.pdf
  file_size: 4336488
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T06:58:40Z
has_accepted_license: '1'
intvolume: '       136'
issue: '14'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Navigating complex phase diagrams in soft matter systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_type: closed access
_id: '21765'
abstract:
- lang: eng
  text: "Dielectric particles of the same material exchange electrical charge during
    collisions or sliding contacts, yet the underlying charge-exchange mechanism is
    still not understood. The fact that particles can become highly charged as a result
    of this effect has significant consequences for many settings, both in nature
    and industry, such as thunderstorms, volcanic eruptions, particle aggregation
    during meteorite and planet formation, and the clogging of industrial granular
    systems. Toward understanding these systems, great efforts have been made to develop
    precise in situ measurements for particle charge, e.g., to determine ensemble
    charge distributions or measure exchange during individual contacts. Here, we
    present experimental results concerning the particle size scaling of the stationary-state
    charge distributions of oxide particles in the sub-millimeter range. We measure
    the charge distributions for large ensembles of monodisperse ZrO2:SiO2 composite
    spheres, ranging from 172 to 545µ⁢m in diameter. These distributions are non-Gaussian
    and collapse to a single master curve when plotted as functions of the surface
    charge density Σ=\U0001D45E/4⁢\U0001D70B⁢\U0001D4452. X-ray fluorescence and atomic
    force microscopy measurements show that the differences in the measured charge
    distributions are not due to variations in chemical composition or surface roughness,
    but rather to size alone. Our findings provide constraints on microscopic models
    for charge exchange, namely that they should lead to steady-state distributions
    that are non-Gaussian and scale in a specific way with particle size."
acknowledgement: This research was supported by ANID Grants QUIMAL No. 160001, FONDECYT
  No. 1221597, and FONDEQUIP No. EQM190177. The authors thank Rodrigo Espinoza for
  the EDS-SEM measurements and Domingo Jullian for fruitful discussions. We also acknowledge
  the technical assistance of Ricardo Silva and Andrés Espinosa at DFI, FCFM, Universidad
  de Chile.
article_number: '045604'
article_processing_charge: No
article_type: original
author:
- first_name: Macarena
  full_name: Lara, Macarena
  last_name: Lara
- first_name: Marcos
  full_name: Flores, Marcos
  last_name: Flores
- first_name: Gustavo
  full_name: Castillo, Gustavo
  last_name: Castillo
- first_name: Santiago
  full_name: Tassara, Santiago
  last_name: Tassara
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
- first_name: Nicolás
  full_name: Mujica, Nicolás
  last_name: Mujica
citation:
  ama: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. Particle
    size scaling of non-Gaussian granular charge distributions. <i>Physical Review
    Materials</i>. 2026;10(4). doi:<a href="https://doi.org/10.1103/qw6t-xqdw">10.1103/qw6t-xqdw</a>
  apa: Lara, M., Flores, M., Castillo, G., Tassara, S., Waitukaitis, S. R., &#38;
    Mujica, N. (2026). Particle size scaling of non-Gaussian granular charge distributions.
    <i>Physical Review Materials</i>. American Physical Society. <a href="https://doi.org/10.1103/qw6t-xqdw">https://doi.org/10.1103/qw6t-xqdw</a>
  chicago: Lara, Macarena, Marcos Flores, Gustavo Castillo, Santiago Tassara, Scott
    R Waitukaitis, and Nicolás Mujica. “Particle Size Scaling of Non-Gaussian Granular
    Charge Distributions.” <i>Physical Review Materials</i>. American Physical Society,
    2026. <a href="https://doi.org/10.1103/qw6t-xqdw">https://doi.org/10.1103/qw6t-xqdw</a>.
  ieee: M. Lara, M. Flores, G. Castillo, S. Tassara, S. R. Waitukaitis, and N. Mujica,
    “Particle size scaling of non-Gaussian granular charge distributions,” <i>Physical
    Review Materials</i>, vol. 10, no. 4. American Physical Society, 2026.
  ista: Lara M, Flores M, Castillo G, Tassara S, Waitukaitis SR, Mujica N. 2026. Particle
    size scaling of non-Gaussian granular charge distributions. Physical Review Materials.
    10(4), 045604.
  mla: Lara, Macarena, et al. “Particle Size Scaling of Non-Gaussian Granular Charge
    Distributions.” <i>Physical Review Materials</i>, vol. 10, no. 4, 045604, American
    Physical Society, 2026, doi:<a href="https://doi.org/10.1103/qw6t-xqdw">10.1103/qw6t-xqdw</a>.
  short: M. Lara, M. Flores, G. Castillo, S. Tassara, S.R. Waitukaitis, N. Mujica,
    Physical Review Materials 10 (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-04-28T07:13:56Z
day: '01'
department:
- _id: ScWa
doi: 10.1103/qw6t-xqdw
intvolume: '        10'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
publication: Physical Review Materials
publication_identifier:
  eissn:
  - 2475-9953
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Particle size scaling of non-Gaussian granular charge distributions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21743'
abstract:
- lang: eng
  text: We present symplectic structures on the shape space of unparameterized space
    curves that generalize the classical Marsden–Weinstein structure. Our method integrates
    the Liouville 1-form of the Marsden–Weinstein structure with Riemannian structures
    that have been introduced in mathematical shape analysis. We also derive Hamiltonian
    vector fields for several classical Hamiltonian functions with respect to these
    new symplectic structures.
acknowledgement: The authors are grateful to Boris Khesin for valuable comments on
  the MW symplectic structure and S. Ishida thanks Albert Chern for insightful discussions
  on space curves and Chris Wojtan for his continuous support. M. Bauer was partially
  supported by NSF grant DMS-1953244 and by the Binational Science Foundation (BSF).
  S. Ishida was partially supported by ERC Consolidator Grant 101045083 “CoDiNA” funded
  by the European Research Council. Some figures were generated by the software Houdini
  and its education license was provided by SideFX. Open access funding provided by
  University of Vienna.
article_number: '45'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Martin
  full_name: Bauer, Martin
  last_name: Bauer
- first_name: Sadashige
  full_name: Ishida, Sadashige
  id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
  last_name: Ishida
  orcid: 0000-0002-3121-3100
- first_name: Peter W.
  full_name: Michor, Peter W.
  last_name: Michor
citation:
  ama: Bauer M, Ishida S, Michor PW. Symplectic structures on the space of space curves.
    <i>Journal of Nonlinear Science</i>. 2026;36(2). doi:<a href="https://doi.org/10.1007/s00332-026-10266-8">10.1007/s00332-026-10266-8</a>
  apa: Bauer, M., Ishida, S., &#38; Michor, P. W. (2026). Symplectic structures on
    the space of space curves. <i>Journal of Nonlinear Science</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00332-026-10266-8">https://doi.org/10.1007/s00332-026-10266-8</a>
  chicago: Bauer, Martin, Sadashige Ishida, and Peter W. Michor. “Symplectic Structures
    on the Space of Space Curves.” <i>Journal of Nonlinear Science</i>. Springer Nature,
    2026. <a href="https://doi.org/10.1007/s00332-026-10266-8">https://doi.org/10.1007/s00332-026-10266-8</a>.
  ieee: M. Bauer, S. Ishida, and P. W. Michor, “Symplectic structures on the space
    of space curves,” <i>Journal of Nonlinear Science</i>, vol. 36, no. 2. Springer
    Nature, 2026.
  ista: Bauer M, Ishida S, Michor PW. 2026. Symplectic structures on the space of
    space curves. Journal of Nonlinear Science. 36(2), 45.
  mla: Bauer, Martin, et al. “Symplectic Structures on the Space of Space Curves.”
    <i>Journal of Nonlinear Science</i>, vol. 36, no. 2, 45, Springer Nature, 2026,
    doi:<a href="https://doi.org/10.1007/s00332-026-10266-8">10.1007/s00332-026-10266-8</a>.
  short: M. Bauer, S. Ishida, P.W. Michor, Journal of Nonlinear Science 36 (2026).
date_created: 2026-04-16T07:29:17Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-04-28T09:59:01Z
day: '15'
ddc:
- '510'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1007/s00332-026-10266-8
external_id:
  arxiv:
  - '2407.19908'
file:
- access_level: open_access
  checksum: 760de2631b6fd7d57bcd5115ed36c0a2
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T09:55:32Z
  date_updated: 2026-04-28T09:55:32Z
  file_id: '21770'
  file_name: 2026_JourNonlinearScience_Bauer.pdf
  file_size: 1108518
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T09:55:32Z
has_accepted_license: '1'
intvolume: '        36'
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: Journal of Nonlinear Science
publication_identifier:
  eissn:
  - 1432-1467
  issn:
  - 0938-8974
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '17361'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Symplectic structures on the space of space curves
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21737'
abstract:
- lang: eng
  text: In calculus, l'Hopital's rule provides a simple way to evaluate the limits
    of quotient functions when both the numerator and denominator vanish. But what
    happens when we move beyond real functions on a real interval? In this article,
    we study when the quotient of two complex-valued functions in higher dimension
    can be defined continuously at the points where both functions vanish. Surprisingly,
    the answer is far subtler than in the real-valued setting. We provide a complete
    characterization for the continuity of the quotient function. We also point out
    why extending this result to smoother quotients remains an intriguing challenge.
acknowledgement: "This project was funded in part by the European Research Council
  (ERC Consolidator Grant 101045083 CoDiNA) and the National Science Foundation CAREER
  Award 2239062.\r\n"
article_number: '2602.09958'
article_processing_charge: No
arxiv: 1
author:
- first_name: Albert
  full_name: Chern, Albert
  last_name: Chern
- first_name: Sadashige
  full_name: Ishida, Sadashige
  id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
  last_name: Ishida
  orcid: 0000-0002-3121-3100
citation:
  ama: Chern A, Ishida S. L’Hopital rules for complex-valued functions in higher dimensions.
    <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2602.09958">10.48550/ARXIV.2602.09958</a>
  apa: Chern, A., &#38; Ishida, S. (n.d.). L’Hopital rules for complex-valued functions
    in higher dimensions. <i>arXiv</i>. <a href="https://doi.org/10.48550/ARXIV.2602.09958">https://doi.org/10.48550/ARXIV.2602.09958</a>
  chicago: Chern, Albert, and Sadashige Ishida. “L’Hopital Rules for Complex-Valued
    Functions in Higher Dimensions.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/ARXIV.2602.09958">https://doi.org/10.48550/ARXIV.2602.09958</a>.
  ieee: A. Chern and S. Ishida, “L’Hopital rules for complex-valued functions in higher
    dimensions,” <i>arXiv</i>. .
  ista: Chern A, Ishida S. L’Hopital rules for complex-valued functions in higher
    dimensions. arXiv, 2602.09958.
  mla: Chern, Albert, and Sadashige Ishida. “L’Hopital Rules for Complex-Valued Functions
    in Higher Dimensions.” <i>ArXiv</i>, 2602.09958, doi:<a href="https://doi.org/10.48550/ARXIV.2602.09958">10.48550/ARXIV.2602.09958</a>.
  short: A. Chern, S. Ishida, ArXiv (n.d.).
corr_author: '1'
date_created: 2026-04-15T16:28:24Z
date_published: 2026-02-10T00:00:00Z
date_updated: 2026-04-28T10:56:30Z
day: '10'
ddc:
- '510'
department:
- _id: GradSch
- _id: ChWo
doi: 10.48550/ARXIV.2602.09958
external_id:
  arxiv:
  - '2602.09958'
file:
- access_level: open_access
  checksum: 6a76591c723d3e949ad5afa9f7dbb2ee
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T10:53:27Z
  date_updated: 2026-04-28T10:53:27Z
  file_id: '21771'
  file_name: 2026_arXiv_2602.09958.pdf
  file_size: 867109
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T10:53:27Z
has_accepted_license: '1'
keyword:
- l’Hopital theorem
- complex functions
language:
- iso: eng
month: '02'
oa: 1
oa_version: Preprint
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: arXiv
publication_status: submitted
status: public
title: L'Hopital rules for complex-valued functions in higher dimensions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21274'
abstract:
- lang: eng
  text: "Many white dwarfs are observed in compact double white dwarf binaries, and
    through the emission of gravitational waves, a large fraction are destined to
    merge. The merger remnants that do not explode in a Type Ia supernova are expected
    to initially be rapidly rotating and highly magnetized. In this work, we present
    our discovery of the variable white dwarf ZTF J200832.79+444939.67, hereafter
    ZTF J2008+4449, as a likely merger remnant showing signs of circumstellar material
    without a stellar or substellar companion. The nature of ZTF J2008+4449 as a merger
    remnant is supported by its physical properties: it is hot (35 500 ± 300 K) and
    massive (1.12 ± 0.03 M\r\n                    <jats:sub>⊙</jats:sub>\r\n                    ),
    rapidly rotating with a period of ≈6.6 minutes, and likely possesses exceptionally
    strong magnetic fields (∼400−600 MG) at its surface. Remarkably, we detect a significant
    period derivative of (1.80 ± 0.09)×10\r\n                    <jats:sup>−12</jats:sup>\r\n
    \                   s/s, indicating that the white dwarf is spinning down, and
    a soft X-ray emission that is inconsistent with photospheric emission. As the
    presence of a mass-transferring stellar or brown dwarf companion is excluded by
    infrared photometry, the detected spin-down and X-ray emission could be tell-tale
    signs of a magnetically driven wind or of interaction with circumstellar material,
    possibly originating from the fallback of gravitationally bound merger ejecta
    or from the tidal disruption of a planetary object. We also detect Balmer emission,
    which requires the presence of ionized hydrogen in the vicinity of the white dwarf,
    showing Doppler shifts as high as ≈2000 km s\r\n                    <jats:sup>−1</jats:sup>\r\n
    \                   . The unusual variability of the Balmer emission on the spin
    period of the white dwarf is consistent with the trapping of a half ring of ionized
    gas in the magnetosphere of the white dwarf.\r\n                  </jats:p>"
acknowledgement: "We thank Lynne Hillenbrand and Soumyadeep Bhattacharjee for helpful
  discussions, and Kishalay De for his help with the WIRC\r\nreduction pipeline. IC
  was supported by NASA through grants from the Space\r\nTelescope Science Institute,
  under NASA contracts NASA.22K1813, NAS5-\r\n26555 and NAS5-03127. TC was supported
  by NASA through the NASA Hubble\r\nFellowship grant HST-HF2-51527.001-A awarded
  by the Space Telescope Science Institute, which is operated by the Association of
  Universities for Research\r\nin Astronomy, Inc., for NASA, under contract NAS5-26555.
  This project has\r\nreceived funding from the European Research Council (ERC) under
  the European Union’s Horizon 2020 research and innovation programme (Grant agreement
  No. 101020057). This work was based on observations obtained with the\r\nSamuel
  Oschin Telescope 48-inch and the 60-inch Telescope at the Palomar\r\nObservatory
  as part of the Zwicky Transient Facility project. ZTF is supported\r\nby the National
  Science Foundation under Grants No. AST-1440341, AST2034437, and currently Award
  #2407588. ZTF receives additional funding from\r\nthe ZTF partnership. Current members
  include Caltech, USA; Caltech/IPAC,\r\nUSA; University of Maryland, USA; University
  of California, Berkeley, USA;\r\nUniversity of Wisconsin at Milwaukee, USA; Cornell
  University, USA; Drexel\r\nUniversity, USA; University of North Carolina at Chapel
  Hill, USA; Institute\r\nof Science and Technology, Austria; National Central University,
  Taiwan, and\r\nOKC, University of Stockholm, Sweden. Operations are conducted by
  Caltech’s\r\nOptical Observatory (COO), Caltech/IPAC, and the University of Washington
  at\r\nSeattle, USA. This work has made use of data from the European Space Agency\r\n(ESA)
  mission Gaia (https://www.cosmos.esa.int/gaia), processed by\r\nthe Gaia Data Processing
  and Analysis Consortium (DPAC, https://www.\r\ncosmos.esa.int/web/gaia/dpac/consortium).
  Funding for the DPAC has been provided by national institutions, in particular the
  institutions participating in the Gaia Multilateral Agreement. The Pan-STARRS1 Surveys
  (PS1)\r\nand the PS1 public science archive have been made possible through contributions
  by the Institute for Astronomy, the University of Hawaii, the PanSTARRS Project
  Office, the Max-Planck Society and its participating institutes, the Max Planck
  Institute for Astronomy, Heidelberg and the Max Planck\r\nInstitute for Extraterrestrial
  Physics, Garching, The Johns Hopkins University,\r\nDurham University, the University
  of Edinburgh, the Queen’s University Belfast,\r\nthe Harvard-Smithsonian Center
  for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated,
  the National Central University of Taiwan, the Space Telescope Science Institute,
  the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued
  through\r\nthe Planetary Science Division of the NASA Science Mission Directorate,
  the\r\nNational Science Foundation Grant No. AST–1238877, the University of Maryland,
  Eotvos Lorand University (ELTE), the Los Alamos National Laboratory,\r\nand the
  Gordon and Betty Moore Foundation. This work made use of Astropy\r\n(http://www.astropy.org):
  a community-developed core Python package\r\nand an ecosystem of tools and resources
  for astronomy (Astropy Collaboration\r\n2013, 2018, 2022)."
article_number: A188
article_processing_charge: Yes
article_type: original
author:
- first_name: Andrei-Alexandru
  full_name: Cristea, Andrei-Alexandru
  id: 4d500bea-31f8-11ee-a48d-d4904fb363c7
  last_name: Cristea
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Tim
  full_name: Cunningham, Tim
  last_name: Cunningham
- first_name: John C.
  full_name: Raymond, John C.
  last_name: Raymond
- first_name: Stephane
  full_name: Vennes, Stephane
  last_name: Vennes
- first_name: Adela
  full_name: Kawka, Adela
  last_name: Kawka
- first_name: Aayush A
  full_name: Desai, Aayush A
  id: 502cfd30-32c1-11ee-a9a4-d8dad5c6739e
  last_name: Desai
- first_name: David R.
  full_name: Miller, David R.
  last_name: Miller
- first_name: J. J.
  full_name: Hermes, J. J.
  last_name: Hermes
- first_name: Jim
  full_name: Fuller, Jim
  last_name: Fuller
- first_name: Jeremy
  full_name: Heyl, Jeremy
  last_name: Heyl
- first_name: Jan
  full_name: van Roestel, Jan
  last_name: van Roestel
- first_name: Kevin B.
  full_name: Burdge, Kevin B.
  last_name: Burdge
- first_name: Antonio C.
  full_name: Rodriguez, Antonio C.
  last_name: Rodriguez
- first_name: Ingrid
  full_name: Pelisoli, Ingrid
  last_name: Pelisoli
- first_name: Boris T.
  full_name: Gänsicke, Boris T.
  last_name: Gänsicke
- first_name: Paula
  full_name: Szkody, Paula
  last_name: Szkody
- first_name: Scott J.
  full_name: Kenyon, Scott J.
  last_name: Kenyon
- first_name: Zach
  full_name: Vanderbosch, Zach
  last_name: Vanderbosch
- first_name: Andrew
  full_name: Drake, Andrew
  last_name: Drake
- first_name: Lilia
  full_name: Ferrario, Lilia
  last_name: Ferrario
- first_name: Dayal
  full_name: Wickramasinghe, Dayal
  last_name: Wickramasinghe
- first_name: Viraj R.
  full_name: Karambelkar, Viraj R.
  last_name: Karambelkar
- first_name: Stephen
  full_name: Justham, Stephen
  last_name: Justham
- first_name: Ruediger
  full_name: Pakmor, Ruediger
  last_name: Pakmor
- first_name: Kareem
  full_name: El-Badry, Kareem
  last_name: El-Badry
- first_name: Thomas
  full_name: Prince, Thomas
  last_name: Prince
- first_name: S. R.
  full_name: Kulkarni, S. R.
  last_name: Kulkarni
- first_name: Matthew J.
  full_name: Graham, Matthew J.
  last_name: Graham
- first_name: Frank J.
  full_name: Masci, Frank J.
  last_name: Masci
- first_name: Steven L.
  full_name: Groom, Steven L.
  last_name: Groom
- first_name: Josiah
  full_name: Purdum, Josiah
  last_name: Purdum
- first_name: Richard
  full_name: Dekany, Richard
  last_name: Dekany
- first_name: Eric C.
  full_name: Bellm, Eric C.
  last_name: Bellm
citation:
  ama: Cristea A-A, Caiazzo I, Cunningham T, et al. A half ring of ionized circumstellar
    material trapped in the magnetosphere of a white dwarf merger remnant. <i>Astronomy
    &#38; Astrophysics</i>. 2026;706. doi:<a href="https://doi.org/10.1051/0004-6361/202556432">10.1051/0004-6361/202556432</a>
  apa: Cristea, A.-A., Caiazzo, I., Cunningham, T., Raymond, J. C., Vennes, S., Kawka,
    A., … Bellm, E. C. (2026). A half ring of ionized circumstellar material trapped
    in the magnetosphere of a white dwarf merger remnant. <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202556432">https://doi.org/10.1051/0004-6361/202556432</a>
  chicago: Cristea, Andrei-Alexandru, Ilaria Caiazzo, Tim Cunningham, John C. Raymond,
    Stephane Vennes, Adela Kawka, Aayush A Desai, et al. “A Half Ring of Ionized Circumstellar
    Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy
    &#38; Astrophysics</i>. EDP Sciences, 2026. <a href="https://doi.org/10.1051/0004-6361/202556432">https://doi.org/10.1051/0004-6361/202556432</a>.
  ieee: A.-A. Cristea <i>et al.</i>, “A half ring of ionized circumstellar material
    trapped in the magnetosphere of a white dwarf merger remnant,” <i>Astronomy &#38;
    Astrophysics</i>, vol. 706. EDP Sciences, 2026.
  ista: Cristea A-A, Caiazzo I, Cunningham T, Raymond JC, Vennes S, Kawka A, Desai
    AA, Miller DR, Hermes JJ, Fuller J, Heyl J, van Roestel J, Burdge KB, Rodriguez
    AC, Pelisoli I, Gänsicke BT, Szkody P, Kenyon SJ, Vanderbosch Z, Drake A, Ferrario
    L, Wickramasinghe D, Karambelkar VR, Justham S, Pakmor R, El-Badry K, Prince T,
    Kulkarni SR, Graham MJ, Masci FJ, Groom SL, Purdum J, Dekany R, Bellm EC. 2026.
    A half ring of ionized circumstellar material trapped in the magnetosphere of
    a white dwarf merger remnant. Astronomy &#38; Astrophysics. 706, A188.
  mla: Cristea, Andrei-Alexandru, et al. “A Half Ring of Ionized Circumstellar Material
    Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy &#38;
    Astrophysics</i>, vol. 706, A188, EDP Sciences, 2026, doi:<a href="https://doi.org/10.1051/0004-6361/202556432">10.1051/0004-6361/202556432</a>.
  short: A.-A. Cristea, I. Caiazzo, T. Cunningham, J.C. Raymond, S. Vennes, A. Kawka,
    A.A. Desai, D.R. Miller, J.J. Hermes, J. Fuller, J. Heyl, J. van Roestel, K.B.
    Burdge, A.C. Rodriguez, I. Pelisoli, B.T. Gänsicke, P. Szkody, S.J. Kenyon, Z.
    Vanderbosch, A. Drake, L. Ferrario, D. Wickramasinghe, V.R. Karambelkar, S. Justham,
    R. Pakmor, K. El-Badry, T. Prince, S.R. Kulkarni, M.J. Graham, F.J. Masci, S.L.
    Groom, J. Purdum, R. Dekany, E.C. Bellm, Astronomy &#38; Astrophysics 706 (2026).
corr_author: '1'
date_created: 2026-02-17T08:12:05Z
date_published: 2026-02-10T00:00:00Z
date_updated: 2026-04-28T12:01:21Z
day: '10'
ddc:
- '520'
department:
- _id: IlCa
- _id: GradSch
doi: 10.1051/0004-6361/202556432
file:
- access_level: open_access
  checksum: 229b688e6e78cab5bb8e2bac366d1575
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  creator: dernst
  date_created: 2026-02-23T12:04:37Z
  date_updated: 2026-02-23T12:04:37Z
  file_id: '21350'
  file_name: 2026_AstronomyAstrophysics_Cristea.pdf
  file_size: 5352853
  relation: main_file
  success: 1
file_date_updated: 2026-02-23T12:04:37Z
has_accepted_license: '1'
intvolume: '       706'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/twos-company-new-class-of-star-remnants/
status: public
title: A half ring of ionized circumstellar material trapped in the magnetosphere
  of a white dwarf merger remnant
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 706
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21485'
abstract:
- lang: eng
  text: Insulating oxides are among the most abundant solid materials in the universe1,2,3.
    Of the many ways in which they influence natural phenomena, perhaps the most consequential
    is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which
    occurs even between samples of the same oxide—yet the symmetry-breaking parameter
    that causes this remains unidentified11,12. Here we show that adventitious carbonaceous
    molecules adsorbed from the environment are the symmetry-breaking factor in same-material
    oxide contact electrification (CE). We use acoustic levitation to measure charge
    exchange between a sphere and a plate composed of identical amorphous silicon
    dioxide (SiO2). Although charging polarity is random for co-prepared samples,
    we control it with baking or plasma treatment. Observing the charge-exchange relaxation
    afterwards, we see dynamics over a timescale of hours and connect this directly
    to the presence of adventitious carbon with time-of-flight mass spectrometry,
    low-energy ion scattering and infrared spectroscopy. Going further, we confirm
    that adventitious carbon can even determine charge exchange among different oxides.
    Our results identify the symmetry-breaking parameter that causes insulating oxides
    to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6,
    while simultaneously highlighting an overlooked factor in CE more broadly.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: LifeSc
acknowledgement: This project has received support from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant
  agreement no. 754411). We acknowledge the state of Lower Austria and the European
  Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges
  support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research
  was supported by the Scientific Service Units of the Institute of Science and Technology
  Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility,
  Scientific Computing facility and Lab Support Facility. We thank the Modic group
  for the use of the Laue camera, T. Zauner for the photography of the experimental
  set-up and R. Möller for insightful discussions. Open access funding provided by
  Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Galien M
  full_name: Grosjean, Galien M
  id: 0C5FDA4A-9CF6-11E9-8939-FF05E6697425
  last_name: Grosjean
  orcid: 0000-0001-5154-417X
- first_name: Markus
  full_name: Ostermann, Markus
  last_name: Ostermann
- first_name: Markus
  full_name: Sauer, Markus
  last_name: Sauer
- first_name: Michael
  full_name: Hahn, Michael
  last_name: Hahn
- first_name: Christian M.
  full_name: Pichler, Christian M.
  last_name: Pichler
- first_name: Florian
  full_name: Fahrnberger, Florian
  last_name: Fahrnberger
- first_name: Felix
  full_name: Pertl, Felix
  id: 6313aec0-15b2-11ec-abd3-ed67d16139af
  last_name: Pertl
  orcid: 0000-0003-0463-5794
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Mason M.
  full_name: Link, Mason M.
  last_name: Link
- first_name: Seong H.
  full_name: Kim, Seong H.
  last_name: Kim
- first_name: Devin L.
  full_name: Schrader, Devin L.
  last_name: Schrader
- first_name: Adriana
  full_name: Blanco, Adriana
  last_name: Blanco
- first_name: Francisco
  full_name: Gracia, Francisco
  last_name: Gracia
- first_name: Nicolás
  full_name: Mujica, Nicolás
  last_name: Mujica
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
citation:
  ama: Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry
    in oxide contact electrification. <i>Nature</i>. 2026;651(8106):626-631. doi:<a
    href="https://doi.org/10.1038/s41586-025-10088-w">10.1038/s41586-025-10088-w</a>
  apa: Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger,
    F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide
    contact electrification. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-025-10088-w">https://doi.org/10.1038/s41586-025-10088-w</a>
  chicago: Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian
    M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks
    Symmetry in Oxide Contact Electrification.” <i>Nature</i>. Springer Nature, 2026.
    <a href="https://doi.org/10.1038/s41586-025-10088-w">https://doi.org/10.1038/s41586-025-10088-w</a>.
  ieee: G. M. Grosjean <i>et al.</i>, “Adventitious carbon breaks symmetry in oxide
    contact electrification,” <i>Nature</i>, vol. 651, no. 8106. Springer Nature,
    pp. 626–631, 2026.
  ista: Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl
    F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis
    SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification.
    Nature. 651(8106), 626–631.
  mla: Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact
    Electrification.” <i>Nature</i>, vol. 651, no. 8106, Springer Nature, 2026, pp.
    626–31, doi:<a href="https://doi.org/10.1038/s41586-025-10088-w">10.1038/s41586-025-10088-w</a>.
  short: G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger,
    F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia,
    N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631.
corr_author: '1'
date_created: 2026-03-23T15:04:00Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-28T12:06:01Z
day: '18'
ddc:
- '540'
department:
- _id: ScWa
- _id: GradSch
- _id: LifeSc
doi: 10.1038/s41586-025-10088-w
ec_funded: 1
external_id:
  pmid:
  - '41851325'
file:
- access_level: open_access
  checksum: dafef9ed575b44be4263e948a47ae056
  content_type: application/pdf
  creator: dernst
  date_created: 2026-03-24T06:57:08Z
  date_updated: 2026-03-24T06:57:08Z
  file_id: '21494'
  file_name: 2026_Nature_Grosjean.pdf
  file_size: 12245694
  relation: main_file
  success: 1
file_date_updated: 2026-03-24T06:57:08Z
has_accepted_license: '1'
intvolume: '       651'
issue: '8106'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 626-631
pmid: 1
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
  call_identifier: H2020
  grant_number: '949120'
  name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/
status: public
title: Adventitious carbon breaks symmetry in oxide contact electrification
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 651
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21015'
abstract:
- lang: eng
  text: Early embryo geometry is one of the most invariant species-specific traits,
    yet its role in ensuring developmental reproducibility and robustness remains
    underexplored. Here we show that in zebrafish, the geometry of the fertilized
    egg—specifically its curvature and volume—serves as a critical initial condition
    triggering a cascade of events that influence development. The embryo geometry
    guides patterned asymmetric cell divisions in the blastoderm, generating radial
    gradients of cell volume and nucleocytoplasmic ratio. These gradients generate
    mitotic phase waves, with the nucleocytoplasmic ratio determining individual cell
    cycle periods independently of other cells. We demonstrate that reducing cell
    autonomy reshapes these waves, emphasizing the instructive role of geometry-derived
    volume patterns in setting the intrinsic period of the cell cycle oscillator.
    In addition to organizing cell cycles, early embryo geometry spatially patterns
    zygotic genome activation at the midblastula transition, a key step in establishing
    embryonic autonomy. Disrupting the embryo shape alters the zygotic genome activation
    pattern and causes ectopic germ layer specification, underscoring the developmental
    significance of geometry. Together, our findings reveal a symmetry-breaking function
    of early embryo geometry in coordinating cell cycle and transcriptional patterning.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: ScienComp
- _id: LifeSc
acknowledgement: We thank N. Petridou (EMBL) for sharing results before publication.
  N.M. was supported by funding from the European Union’s Horizon 2020 programme under
  the Marie Skłodowska-Curie COFUND Actions ISTplus grant agreement number 754411.
  Y.I.L. acknowledges funding from the European Union’s Horizon 2020 research and
  innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413.
  The research was supported by funding to C.-P.H. from the NOMIS Foundation, Project
  ID 1.844. We would like to thank past and present members of the Heisenberg and
  Hannezo groups for discussions, particularly S. Shamipour, V. Doddihal, M. Jovic,
  N. Hino, F. N. Arslan, R. Kobylinska and C. Camelo for feedback on the draft manuscript.
  This research was supported by the Scientific Service Units (SSU) of Institute of
  Science and Technology Austria through resources provided by the Aquatics Facility,
  Imaging & Optics Facility (IOF), Scientific Computing (SciComp) facility and Lab
  Support Facility (LSF). Open access funding provided by Institute of Science and
  Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Nikhil
  full_name: Mishra, Nikhil
  id: C4D70E82-1081-11EA-B3ED-9A4C3DDC885E
  last_name: Mishra
  orcid: 0000-0002-6425-5788
- first_name: Yuting I
  full_name: Li, Yuting I
  id: ee7a5ca8-8b71-11ed-b662-b3341c05b7eb
  last_name: Li
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. Geometry-driven asymmetric cell
    divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo.
    <i>Nature Physics</i>. 2026;22:139-150. doi:<a href="https://doi.org/10.1038/s41567-025-03122-1">10.1038/s41567-025-03122-1</a>
  apa: Mishra, N., Li, Y. I., Hannezo, E. B., &#38; Heisenberg, C.-P. J. (2026). Geometry-driven
    asymmetric cell divisions pattern cell cycles and zygotic genome activation in
    the zebrafish embryo. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-025-03122-1">https://doi.org/10.1038/s41567-025-03122-1</a>
  chicago: Mishra, Nikhil, Yuting I Li, Edouard B Hannezo, and Carl-Philipp J Heisenberg.
    “Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome
    Activation in the Zebrafish Embryo.” <i>Nature Physics</i>. Springer Nature, 2026.
    <a href="https://doi.org/10.1038/s41567-025-03122-1">https://doi.org/10.1038/s41567-025-03122-1</a>.
  ieee: N. Mishra, Y. I. Li, E. B. Hannezo, and C.-P. J. Heisenberg, “Geometry-driven
    asymmetric cell divisions pattern cell cycles and zygotic genome activation in
    the zebrafish embryo,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 139–150,
    2026.
  ista: Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. 2026. Geometry-driven asymmetric
    cell divisions pattern cell cycles and zygotic genome activation in the zebrafish
    embryo. Nature Physics. 22, 139–150.
  mla: Mishra, Nikhil, et al. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell
    Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” <i>Nature Physics</i>,
    vol. 22, Springer Nature, 2026, pp. 139–50, doi:<a href="https://doi.org/10.1038/s41567-025-03122-1">10.1038/s41567-025-03122-1</a>.
  short: N. Mishra, Y.I. Li, E.B. Hannezo, C.-P.J. Heisenberg, Nature Physics 22 (2026)
    139–150.
corr_author: '1'
date_created: 2026-01-20T10:12:19Z
date_published: 2026-01-05T00:00:00Z
date_updated: 2026-04-28T12:55:30Z
day: '05'
ddc:
- '570'
department:
- _id: EdHa
- _id: CaHe
doi: 10.1038/s41567-025-03122-1
ec_funded: 1
external_id:
  oaworkid:
  - W7118187193
file:
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  creator: dernst
  date_created: 2026-01-21T08:21:11Z
  date_updated: 2026-01-21T08:21:11Z
  file_id: '21026'
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file_date_updated: 2026-01-21T08:21:11Z
has_accepted_license: '1'
intvolume: '        22'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
oaworkid: 1
page: 139-150
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: 917c023a-16d5-11f0-9cad-eb5cafc52090
  name: Cytoplasmic self-organization into cell-like compartments as a common guiding
    principle in early animal development
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
  issnl:
  - ' 1745-2473'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: research_data
    url: https://ista.ac.at/en/news/geometry-shapes-life/
scopus_import: '1'
status: public
title: Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome
  activation in the zebrafish embryo
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 22
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21382'
abstract:
- lang: eng
  text: The exceptional energy-harvesting efficiency of lead-halide perovskites arises
    from unusually long photocarrier diffusion lengths and recombination lifetimes
    that persist even in defect-rich, solution-grown samples. Paradoxically, perovskites
    are also known for having very short exciton decay times. Here, we resolve this
    apparent contradiction by showing that key optoelectronic properties of perovskites
    can be explained by localized flexoelectric polarization confined to interfaces
    between domains of spontaneous strain. Using birefringence imaging, electrochemical
    staining, and zero-bias photocurrent measurements, we visualize the domain structure
    and directly probe the associated internal fields in nominally cubic single crystals
    of methylammonium lead bromide. We demonstrate that localized flexoelectric fields
    spatially separate electrons and holes to opposite sides of domain walls, exponentially
    suppressing recombination. Domain walls thus act as efficient mesoscopic transport
    channels for long-lived photocarriers, microscopically linking structural heterogeneity
    to charge transport and offering mechanistically informed design principles for
    perovskite solar-energy technologies.
acknowledged_ssus:
- _id: Bio
- _id: M-Shop
acknowledgement: We are grateful to A. G. Volosniev for the valuable discussions.
  We thank D. Milius for the assistance with microscopy. D. R. would like to thank
  F. Filakovský and T. Čuchráč for the valuable discussions. This research was supported
  by the Scientific Service Units (SSU) of ISTA through resources provided by the
  Imaging & Optics Facility (IOF) and the Miba Machine Shop Facility (MS).
article_number: '946'
article_processing_charge: Yes
article_type: original
author:
- first_name: Dmytro
  full_name: Rak, Dmytro
  id: 70313b46-47c2-11ec-9e88-cd79101918fe
  last_name: Rak
- first_name: Dusan
  full_name: Lorenc, Dusan
  id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87
  last_name: Lorenc
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Ayan A.
  full_name: Zhumekenov, Ayan A.
  last_name: Zhumekenov
- first_name: Osman M.
  full_name: Bakr, Osman M.
  last_name: Bakr
- first_name: Zhanybek
  full_name: Alpichshev, Zhanybek
  id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Alpichshev
  orcid: 0000-0002-7183-5203
citation:
  ama: Rak D, Lorenc D, Balazs D, Zhumekenov AA, Bakr OM, Alpichshev Z. Flexoelectric
    domain walls enable charge separation and transport in cubic perovskites. <i>Nature
    Communications</i>. 2026;17. doi:<a href="https://doi.org/10.1038/s41467-026-68660-5">10.1038/s41467-026-68660-5</a>
  apa: Rak, D., Lorenc, D., Balazs, D., Zhumekenov, A. A., Bakr, O. M., &#38; Alpichshev,
    Z. (2026). Flexoelectric domain walls enable charge separation and transport in
    cubic perovskites. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-026-68660-5">https://doi.org/10.1038/s41467-026-68660-5</a>
  chicago: Rak, Dmytro, Dusan Lorenc, Daniel Balazs, Ayan A. Zhumekenov, Osman M.
    Bakr, and Zhanybek Alpichshev. “Flexoelectric Domain Walls Enable Charge Separation
    and Transport in Cubic Perovskites.” <i>Nature Communications</i>. Springer Nature,
    2026. <a href="https://doi.org/10.1038/s41467-026-68660-5">https://doi.org/10.1038/s41467-026-68660-5</a>.
  ieee: D. Rak, D. Lorenc, D. Balazs, A. A. Zhumekenov, O. M. Bakr, and Z. Alpichshev,
    “Flexoelectric domain walls enable charge separation and transport in cubic perovskites,”
    <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.
  ista: Rak D, Lorenc D, Balazs D, Zhumekenov AA, Bakr OM, Alpichshev Z. 2026. Flexoelectric
    domain walls enable charge separation and transport in cubic perovskites. Nature
    Communications. 17, 946.
  mla: Rak, Dmytro, et al. “Flexoelectric Domain Walls Enable Charge Separation and
    Transport in Cubic Perovskites.” <i>Nature Communications</i>, vol. 17, 946, Springer
    Nature, 2026, doi:<a href="https://doi.org/10.1038/s41467-026-68660-5">10.1038/s41467-026-68660-5</a>.
  short: D. Rak, D. Lorenc, D. Balazs, A.A. Zhumekenov, O.M. Bakr, Z. Alpichshev,
    Nature Communications 17 (2026).
corr_author: '1'
date_created: 2026-03-02T10:06:58Z
date_published: 2026-02-16T00:00:00Z
date_updated: 2026-04-28T12:12:46Z
day: '16'
ddc:
- '530'
department:
- _id: ZhAl
- _id: LifeSc
doi: 10.1038/s41467-026-68660-5
external_id:
  pmid:
  - '41698893'
file:
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  checksum: dd7a98de892d0b5abefca7e290ca0f77
  content_type: application/pdf
  creator: dernst
  date_created: 2026-03-02T14:27:56Z
  date_updated: 2026-03-02T14:27:56Z
  file_id: '21390'
  file_name: 2026_NatureComm_Rak.pdf
  file_size: 2570918
  relation: main_file
  success: 1
file_date_updated: 2026-03-02T14:27:56Z
has_accepted_license: '1'
intvolume: '        17'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/explaining-next-generation-solar-cells/
scopus_import: '1'
status: public
title: Flexoelectric domain walls enable charge separation and transport in cubic
  perovskites
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 17
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21488'
abstract:
- lang: eng
  text: Human height is a model for the genetic analysis of complex traits, and recent
    studies suggest the presence of thousands of common genetic variant associations
    and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic
    paradigm based on approximate message passing (genomic vector approximate message
    passing [gVAMP]) for identifying DNA sequence variants associated with complex
    traits and common diseases in large-scale whole-genome sequencing (WGS) data.
    We show that gVAMP accurately localizes associations to variants with the correct
    frequency and position in the DNA, outperforming existing fine-mapping methods
    in selecting the appropriate genetic variants within WGS data. We then apply gVAMP
    to jointly model the relationship of tens of millions of WGS variants with human
    height in hundreds of thousands of UK Biobank individuals. We identify 59 rare
    variants and gene burden scores alongside many hundreds of DNA regions containing
    common variant associations and show that understanding the genetic basis of complex
    traits will require the joint analysis of hundreds of millions of variables measured
    on millions of people. The polygenic risk scores obtained from gVAMP have high
    accuracy (including a prediction accuracy of ∼46% for human height) and outperform
    current methods for downstream tasks such as mixed linear model association testing
    across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation
    for a wider range of analyses in WGS data.
acknowledgement: We thank Malgorzata Borczyk for creating the gene burden scores.
  We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter,
  Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for
  providing valuable suggestions and comments on earlier versions of the work. This
  project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to
  M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364),
  and core funding from ISTA. High-performance computing was supported by the Scientific
  Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).
  We would like to acknowledge the participants and investigators of the UK Biobank
  study. We gratefully acknowledge the All of Us participants for their contributions,
  without whom this research would not have been possible. We also thank the National
  Institutes of Health All of Us Research Program for making available the participant
  data (and/or samples and/or cohort) examined in this study.
article_number: '101162'
article_processing_charge: Yes
article_type: original
author:
- first_name: Al
  full_name: Depope, Al
  id: 0b77531d-dbcd-11ea-9d1d-a8eee0bf3830
  last_name: Depope
- first_name: Jakub
  full_name: Bajzik, Jakub
  id: b995e25b-8c4b-11ed-a6d8-f71b7bcd6122
  last_name: Bajzik
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
citation:
  ama: Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome
    sequencing data for human height via approximate message passing. <i>Cell Genomics</i>.
    2026. doi:<a href="https://doi.org/10.1016/j.xgen.2026.101162">10.1016/j.xgen.2026.101162</a>
  apa: Depope, A., Bajzik, J., Mondelli, M., &#38; Robinson, M. R. (2026). Joint modeling
    of whole-genome sequencing data for human height via approximate message passing.
    <i>Cell Genomics</i>. Elsevier. <a href="https://doi.org/10.1016/j.xgen.2026.101162">https://doi.org/10.1016/j.xgen.2026.101162</a>
  chicago: Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson.
    “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate
    Message Passing.” <i>Cell Genomics</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.xgen.2026.101162">https://doi.org/10.1016/j.xgen.2026.101162</a>.
  ieee: A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of
    whole-genome sequencing data for human height via approximate message passing,”
    <i>Cell Genomics</i>. Elsevier, 2026.
  ista: Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome
    sequencing data for human height via approximate message passing. Cell Genomics.,
    101162.
  mla: Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human
    Height via Approximate Message Passing.” <i>Cell Genomics</i>, 101162, Elsevier,
    2026, doi:<a href="https://doi.org/10.1016/j.xgen.2026.101162">10.1016/j.xgen.2026.101162</a>.
  short: A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics (2026).
corr_author: '1'
date_created: 2026-03-23T15:10:03Z
date_published: 2026-02-18T00:00:00Z
date_updated: 2026-04-28T12:08:37Z
day: '18'
ddc:
- '000'
- '570'
department:
- _id: MaMo
- _id: MaRo
doi: 10.1016/j.xgen.2026.101162
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.xgen.2026.101162
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
  name: Prix Lopez-Loretta 2019 - Marco Mondelli
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
  grant_number: '101161364'
  name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
  grant_number: PCEGP3_181181
  name: Improving estimation and prediction of common complex disease risk
publication: Cell Genomics
publication_identifier:
  eissn:
  - 2666-979X
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/big-data-and-human-height/
status: public
title: Joint modeling of whole-genome sequencing data for human height via approximate
  message passing
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21766'
abstract:
- lang: eng
  text: We provide a new characterisation of the decades old open problem of extending
    bilipschitz mappings given on a Euclidean separated net. In particular, this allows
    for the complete positive solution of the open problem in dimension two. Along
    the way, we develop a set of tools for bilipschitz extensions of mappings between
    subsets of Euclidean spaces.
acknowledgement: "The present work developed from a research visit of M.D. to V.K.
  at IST Austria, funded by\r\na London Mathematical Society Research in Pairs grant.
  This work was done while V.K. was fully funded by the Austria Science Fund (FWF)
  [M 3100-N]."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Dymond, Michael
  last_name: Dymond
- first_name: Vojtech
  full_name: Kaluza, Vojtech
  id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
  last_name: Kaluza
  orcid: 0000-0002-2512-8698
citation:
  ama: Dymond M, Kaluza V. Extending bilipschitz mappings between separated nets.
    <i>Annales Fennici Mathematici</i>. 2026;51(1):237-260. doi:<a href="https://doi.org/10.54330/afm.181562">10.54330/afm.181562</a>
  apa: Dymond, M., &#38; Kaluza, V. (2026). Extending bilipschitz mappings between
    separated nets. <i>Annales Fennici Mathematici</i>. Finnish Mathematical Society.
    <a href="https://doi.org/10.54330/afm.181562">https://doi.org/10.54330/afm.181562</a>
  chicago: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
    Separated Nets.” <i>Annales Fennici Mathematici</i>. Finnish Mathematical Society,
    2026. <a href="https://doi.org/10.54330/afm.181562">https://doi.org/10.54330/afm.181562</a>.
  ieee: M. Dymond and V. Kaluza, “Extending bilipschitz mappings between separated
    nets,” <i>Annales Fennici Mathematici</i>, vol. 51, no. 1. Finnish Mathematical
    Society, pp. 237–260, 2026.
  ista: Dymond M, Kaluza V. 2026. Extending bilipschitz mappings between separated
    nets. Annales Fennici Mathematici. 51(1), 237–260.
  mla: Dymond, Michael, and Vojtech Kaluza. “Extending Bilipschitz Mappings between
    Separated Nets.” <i>Annales Fennici Mathematici</i>, vol. 51, no. 1, Finnish Mathematical
    Society, 2026, pp. 237–60, doi:<a href="https://doi.org/10.54330/afm.181562">10.54330/afm.181562</a>.
  short: M. Dymond, V. Kaluza, Annales Fennici Mathematici 51 (2026) 237–260.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-17T00:00:00Z
date_updated: 2026-04-28T12:06:00Z
day: '17'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.54330/afm.181562
external_id:
  arxiv:
  - '2507.22007'
file:
- access_level: open_access
  checksum: 442023926a3803d5d6ca8db8dbc4af1c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T12:03:13Z
  date_updated: 2026-04-28T12:03:13Z
  file_id: '21772'
  file_name: 2026_AnnalesFenniciMath_Dymond.pdf
  file_size: 342082
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T12:03:13Z
has_accepted_license: '1'
intvolume: '        51'
issue: '1'
keyword:
- Lipschitz
- bilipschitz
- extension
- separated net.
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 237-260
project:
- _id: fc35eaa2-9c52-11eb-aca3-88501ab155e9
  grant_number: M03100
  name: Spectra and topology of graphs and of simplicial complexes
publication: Annales Fennici Mathematici
publication_identifier:
  eissn:
  - 2737-114X
  issn:
  - 2737-0690
publication_status: published
publisher: Finnish Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extending bilipschitz mappings between separated nets
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 51
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21006'
abstract:
- lang: eng
  text: Modern experimental methods in programmable self-assembly make it possible
    to precisely design particle concentrations, shapes and interactions. However,
    more physical insight is needed before we can take full advantage of this vast
    design space to assemble nanostructures with complex form and function. Here we
    show how a substantial part of this design space can be quickly and comprehensively
    understood by identifying a class of thermodynamic constraints that act on it.
    These thermodynamic constraints form a high-dimensional convex polyhedron that
    determines which nanostructures can be assembled at high equilibrium yield and
    reveals limitations that govern the coexistence of structures. We validate our
    predictions through detailed, quantitative assembly experiments of nanoscale particles
    synthesized using DNA origami. Our results uncover physical relationships underpinning
    many-component programmable self-assembly in equilibrium and form the basis for
    robust inverse design, applicable to various systems from biological protein complexes
    to synthetic nanomachines.
acknowledgement: We thank B. Isaac and A. Tiano for their technical support with the
  electron microscopy and S. Waitukaitis for helpful comments on the manuscript. The
  TEM images were prepared and imaged at the Brandeis Electron Microscopy facility.
  This work was supported by the Gesellschaft für Forschungsförderung Niederösterreich
  under project FTI23-G-011 (M.C.H. and C.P.G.), the Brandeis University Materials
  Research Science and Engineering Center (MRSEC) under grant number NSF DMR-2011846
  (T.E.V., D.H. and W.B.R.) and the Smith Family Foundation (W.B.R.). Open access
  funding provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Maximilian
  full_name: Hübl, Maximilian
  id: 5eb8629e-15b2-11ec-abd3-e6f3e5e01f32
  last_name: Hübl
- first_name: Thomas E.
  full_name: Videbæk, Thomas E.
  last_name: Videbæk
- first_name: Daichi
  full_name: Hayakawa, Daichi
  last_name: Hayakawa
- first_name: W. Benjamin
  full_name: Rogers, W. Benjamin
  last_name: Rogers
- first_name: Carl Peter
  full_name: Goodrich, Carl Peter
  id: EB352CD2-F68A-11E9-89C5-A432E6697425
  last_name: Goodrich
  orcid: 0000-0002-1307-5074
citation:
  ama: Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. A polyhedral structure
    controls programmable self-assembly. <i>Nature Physics</i>. 2026. doi:<a href="https://doi.org/10.1038/s41567-025-03120-3">10.1038/s41567-025-03120-3</a>
  apa: Hübl, M., Videbæk, T. E., Hayakawa, D., Rogers, W. B., &#38; Goodrich, C. P.
    (2026). A polyhedral structure controls programmable self-assembly. <i>Nature
    Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-025-03120-3">https://doi.org/10.1038/s41567-025-03120-3</a>
  chicago: Hübl, Maximilian, Thomas E. Videbæk, Daichi Hayakawa, W. Benjamin Rogers,
    and Carl Peter Goodrich. “A Polyhedral Structure Controls Programmable Self-Assembly.”
    <i>Nature Physics</i>. Springer Nature, 2026. <a href="https://doi.org/10.1038/s41567-025-03120-3">https://doi.org/10.1038/s41567-025-03120-3</a>.
  ieee: M. Hübl, T. E. Videbæk, D. Hayakawa, W. B. Rogers, and C. P. Goodrich, “A
    polyhedral structure controls programmable self-assembly,” <i>Nature Physics</i>.
    Springer Nature, 2026.
  ista: Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. 2026. A polyhedral
    structure controls programmable self-assembly. Nature Physics.
  mla: Hübl, Maximilian, et al. “A Polyhedral Structure Controls Programmable Self-Assembly.”
    <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41567-025-03120-3">10.1038/s41567-025-03120-3</a>.
  short: M. Hübl, T.E. Videbæk, D. Hayakawa, W.B. Rogers, C.P. Goodrich, Nature Physics
    (2026).
corr_author: '1'
date_created: 2026-01-20T10:02:19Z
date_published: 2026-01-08T00:00:00Z
date_updated: 2026-04-28T11:56:45Z
day: '08'
ddc:
- '570'
- '540'
department:
- _id: CaGo
- _id: GradSch
doi: 10.1038/s41567-025-03120-3
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41567-025-03120-3
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 8dd93da8-16d5-11f0-9cad-d2c70200d9a5
  grant_number: FTI23-G-011
  name: Dynamically reconfigurable self-assembly with triangular DNA-origami bricks
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/behind-natures-blueprints/
scopus_import: '1'
status: public
title: A polyhedral structure controls programmable self-assembly
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21760'
abstract:
- lang: eng
  text: 3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua
    and 2I/Borisov. Its unusually high excess velocity and active cometary nature
    make it a key probe of the Galactic population of icy planetesimals. Understanding
    its origin requires its past trajectory through the Galaxy to be traced and the
    possible role of stellar encounters to be assessed, both as a potential origin
    and a perturber to its orbit. We integrated the orbit of 3I/ATLAS backward in
    time for 10 Myr, together with a sample of Gaia DR3 stars with high-quality astrometry
    and radial velocities, to identify close passages within 2 pc. We identify 93
    nominal encounters, 62 of which are significant at the 2σ level. However, none
    of these encounters produced any meaningful perturbation. The strongest perturber
    Gaia DR3 6863591389529611264 at 0.30 pc and with a relative velocity of 35 km
    s−1, imparted only a velocity change of ∣Δv∣  ≃  5  ×  10−4 km s−1 to the orbit
    of 3I/ATLAS. Our results indicate that no stellar flybys within the past 10 Myr
    and 500 pc contained in Gaia DR3 can account for the present trajectory of 3I/ATLAS
    or be associated with its origin. We further show that 3I/ATLAS is kinematically
    consistent with a thin-disk population, despite its large peculiar velocity.
acknowledgement: We thank the anonymous referee for a careful reading of the manuscript
  and for constructive comments that improved the paper. X.P.C. and S.T. thank J.L.
  Gragera-Más and Ylva Götberg for their valuable feedback and comments. X.P.C. acknowledges
  financial support from the Spanish National Programme for the Promotion of Talent
  and its Employability grant PRE2022-104959 cofunded by the European Social Fund.
  S.T. acknowledges the funding from the European Union’s Horizon 2020 research and
  innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413.
  E.V. acknowledges support from the DISCOBOLO project funded by the Spanish Ministerio
  de Ciencia, Innovación y Universidades under grant PID2021-127289NB-I00. A.J.M.
  acknowledges support from the Swedish National Space Agency (Career grant 2023-00146).
  X.P.C. and M.M. acknowledge support from the Spanish Ministerio de Ciencia, Innovaciòn
  y Universidades under grants PID2021122842OB-C22 and PID2024-157964OB-C22; from
  the Xunta de Galicia and the European Union (FEDER Galicia 2021-2027 Program) Ref.
  ED431B 2024/21, ED431B 2024/02, and CITIC ED431G 2023/01. This work has made use
  of data from the European Space Agency (ESA) Gaia mission and processed by the Gaia
  Data Processing and Analysis Consortium (DPAC). Funding for the DPAC has been provided
  by national institutions, particularly the institutions participating in the Gaia
  Multilateral Agreement.
article_number: '146'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: X.
  full_name: Pérez-Couto, X.
  last_name: Pérez-Couto
- first_name: Santiago
  full_name: Torres Rodriguez, Santiago
  id: a8df4360-4328-11ee-8f1a-e502d0c83fc2
  last_name: Torres Rodriguez
  orcid: 0000-0002-3150-8988
- first_name: E.
  full_name: Villaver, E.
  last_name: Villaver
- first_name: A. J.
  full_name: Mustill, A. J.
  last_name: Mustill
- first_name: M.
  full_name: Manteiga, M.
  last_name: Manteiga
citation:
  ama: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 3I/ATLAS:
    In search of the witnesses to its voyage. <i>The Astrophysical Journal</i>. 2026;1001(2).
    doi:<a href="https://doi.org/10.3847/1538-4357/ae56ff">10.3847/1538-4357/ae56ff</a>'
  apa: 'Pérez-Couto, X., Torres Rodriguez, S., Villaver, E., Mustill, A. J., &#38;
    Manteiga, M. (2026). 3I/ATLAS: In search of the witnesses to its voyage. <i>The
    Astrophysical Journal</i>. IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/ae56ff">https://doi.org/10.3847/1538-4357/ae56ff</a>'
  chicago: 'Pérez-Couto, X., Santiago Torres Rodriguez, E. Villaver, A. J. Mustill,
    and M. Manteiga. “3I/ATLAS: In Search of the Witnesses to Its Voyage.” <i>The
    Astrophysical Journal</i>. IOP Publishing, 2026. <a href="https://doi.org/10.3847/1538-4357/ae56ff">https://doi.org/10.3847/1538-4357/ae56ff</a>.'
  ieee: 'X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A. J. Mustill, and M. Manteiga,
    “3I/ATLAS: In search of the witnesses to its voyage,” <i>The Astrophysical Journal</i>,
    vol. 1001, no. 2. IOP Publishing, 2026.'
  ista: 'Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 2026.
    3I/ATLAS: In search of the witnesses to its voyage. The Astrophysical Journal.
    1001(2), 146.'
  mla: 'Pérez-Couto, X., et al. “3I/ATLAS: In Search of the Witnesses to Its Voyage.”
    <i>The Astrophysical Journal</i>, vol. 1001, no. 2, 146, IOP Publishing, 2026,
    doi:<a href="https://doi.org/10.3847/1538-4357/ae56ff">10.3847/1538-4357/ae56ff</a>.'
  short: X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A.J. Mustill, M. Manteiga,
    The Astrophysical Journal 1001 (2026).
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:08:39Z
day: '20'
ddc:
- '520'
department:
- _id: LiBu
doi: 10.3847/1538-4357/ae56ff
ec_funded: 1
external_id:
  arxiv:
  - '2509.07678'
file:
- access_level: open_access
  checksum: c3daf49261a9933c079854c38eec316f
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:06:00Z
  date_updated: 2026-04-28T13:06:00Z
  file_id: '21773'
  file_name: 2026_AstrophysicalJournal_PerezCouto.pdf
  file_size: 2905627
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:06:00Z
has_accepted_license: '1'
intvolume: '      1001'
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: '3I/ATLAS: In search of the witnesses to its voyage'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1001
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21761'
abstract:
- lang: eng
  text: Neural tube closure is a critical morphogenetic process in vertebrate development,
    and failure to close cranial regions such as the hindbrain neuropore (HNP) leads
    to severe congenital malformations. While mechanical forces such as actomyosin
    purse-string contraction and directional cell crawling have been implicated in
    driving HNP closure, how these forces organize local cell shape and motion to
    produce large-scale tissue remodeling remains poorly understood. Using live and
    fixed imaging of mouse embryos combined with cell-based biophysical modeling,
    we show that these force-generating mechanisms are insufficient to explain the
    reproducible patterns of cell elongation and nematic alignment observed at the
    HNP border. Instead, we show that local anisotropic stress and cytoskeletal organization
    are required to generate these patterns and promote midline cell motion. Our model
    captures key features of cell shape dynamics and emergent nematic order, which
    we confirm experimentally, including the alignment of actin fibers with cell shape
    and enhanced midline cell speed. Comparative analysis with chick embryos, which
    lack supracellular purse strings, supports a conserved link between tension generation
    and cellular patterning. These findings establish a physical framework connecting
    force generation, cell shape anisotropy, and tissue morphodynamics during epithelial
    gap closure.
acknowledgement: S.B. acknowledges support from the National Institutes of Health
  (NIH R35 GM143042) and the National Science Foundation (NSF MCB-2203601). G.L.G.
  acknowledges support from the Wellcome Trust (211112/Z/18/Z), the Royal Society
  (RG\R2\232082), and the Leverhulme Trust (RPG-2024-147). E.M. acknowledges support
  from European Union’s Horizon 2021 Marie Sklodowska-Curie grant agreement no. 101067028.
  F.P.-V. acknowledges support from the NOMIS foundation. The surface subtraction
  macro is courtesy of Dr. Dale Moulding and available on GitHub (https://github.com/DaleMoulding/Fiji-Macros).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernanda L
  full_name: Perez Verdugo, Fernanda L
  id: 4ecec223-9070-11ef-a0a9-bc76077bea8d
  last_name: Perez Verdugo
- first_name: Eirini
  full_name: Maniou, Eirini
  last_name: Maniou
- first_name: Gabriel L.
  full_name: Galea, Gabriel L.
  last_name: Galea
- first_name: Shiladitya
  full_name: Banerjee, Shiladitya
  last_name: Banerjee
citation:
  ama: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. Mechanosensitive feedback
    organizes cell shape and motion during hindbrain neuropore morphogenesis. <i>Current
    Biology</i>. 2026;36(8):1903-1917.e5. doi:<a href="https://doi.org/10.1016/j.cub.2026.02.068">10.1016/j.cub.2026.02.068</a>
  apa: Perez Verdugo, F. L., Maniou, E., Galea, G. L., &#38; Banerjee, S. (2026).
    Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore
    morphogenesis. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2026.02.068">https://doi.org/10.1016/j.cub.2026.02.068</a>
  chicago: Perez Verdugo, Fernanda L, Eirini Maniou, Gabriel L. Galea, and Shiladitya
    Banerjee. “Mechanosensitive Feedback Organizes Cell Shape and Motion during Hindbrain
    Neuropore Morphogenesis.” <i>Current Biology</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.cub.2026.02.068">https://doi.org/10.1016/j.cub.2026.02.068</a>.
  ieee: F. L. Perez Verdugo, E. Maniou, G. L. Galea, and S. Banerjee, “Mechanosensitive
    feedback organizes cell shape and motion during hindbrain neuropore morphogenesis,”
    <i>Current Biology</i>, vol. 36, no. 8. Elsevier, p. 1903–1917.e5, 2026.
  ista: Perez Verdugo FL, Maniou E, Galea GL, Banerjee S. 2026. Mechanosensitive feedback
    organizes cell shape and motion during hindbrain neuropore morphogenesis. Current
    Biology. 36(8), 1903–1917.e5.
  mla: Perez Verdugo, Fernanda L., et al. “Mechanosensitive Feedback Organizes Cell
    Shape and Motion during Hindbrain Neuropore Morphogenesis.” <i>Current Biology</i>,
    vol. 36, no. 8, Elsevier, 2026, p. 1903–1917.e5, doi:<a href="https://doi.org/10.1016/j.cub.2026.02.068">10.1016/j.cub.2026.02.068</a>.
  short: F.L. Perez Verdugo, E. Maniou, G.L. Galea, S. Banerjee, Current Biology 36
    (2026) 1903–1917.e5.
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-20T00:00:00Z
date_updated: 2026-04-28T13:15:42Z
day: '20'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1016/j.cub.2026.02.068
external_id:
  pmid:
  - '41881011'
file:
- access_level: open_access
  checksum: 80ae45457b4682c50c84f54de15aa9a8
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:13:40Z
  date_updated: 2026-04-28T13:13:40Z
  file_id: '21774'
  file_name: 2026_CurrentBiology_PerezVerdugo.pdf
  file_size: 13402043
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:13:40Z
has_accepted_license: '1'
intvolume: '        36'
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1903-1917.e5
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanosensitive feedback organizes cell shape and motion during hindbrain
  neuropore morphogenesis
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
OA_type: closed access
_id: '21762'
abstract:
- lang: eng
  text: Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular
    organization. The plasmid-encoded ParMRC system forms actin-like filaments that
    segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena
    sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal
    system named CorMR with a function in cell shape control rather than DNA segregation.
    Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed
    that CorM formed dynamically unstable, antiparallel double-stranded filaments
    that were recruited to the membrane by CorR through an amphipathic helix conserved
    in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which
    excluded them from the poles and division plane. Comparative genomics indicated
    that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity,
    highlighting the evolutionary plasticity of cytoskeletal systems in bacteria.
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all members of the Loose lab at ISTA for helpful discussions;
  M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University)
  for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial
  strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial
  strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing
  the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix
  screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data
  collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work
  was supported by the Scientific Service Units (SSU) of ISTA through resources provided
  by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the
  Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work
  was funded by the European Union’s Horizon 2020 research and innovation program
  (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council
  (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National
  Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques
  et Letitia Lopez-Loreta Foundation (G.L.W.)."
article_number: eaea6343
article_processing_charge: No
article_type: original
author:
- first_name: Benjamin L
  full_name: Springstein, Benjamin L
  id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083
  last_name: Springstein
  orcid: 0000-0002-3461-5391
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
  orcid: 0000-0003-2311-2112
- first_name: Daniela
  full_name: Megrian, Daniela
  last_name: Megrian
- first_name: Roman
  full_name: Hajdu, Roman
  id: ffab949d-133f-11ed-8f02-94de21ace503
  last_name: Hajdu
- first_name: Dustin M.
  full_name: Hanke, Dustin M.
  last_name: Hanke
- first_name: Bettina
  full_name: Zens, Bettina
  id: 45FD126C-F248-11E8-B48F-1D18A9856A87
  last_name: Zens
  orcid: 0000-0002-9561-1239
- first_name: Gregor L.
  full_name: Weiss, Gregor L.
  last_name: Weiss
- first_name: Florian Km
  full_name: Schur, Florian Km
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
citation:
  ama: Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation
    machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795).
    doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>
  apa: Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens,
    B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. <i>Science</i>. AAAS. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>
  chicago: Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu,
    Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose.
    “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling
    Cell Shape.” <i>Science</i>. AAAS, 2026. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>.
  ieee: B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery
    into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392,
    no. 6795. AAAS, 2026.
  ista: Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL,
    Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. Science. 392(6795), eaea6343.
  mla: Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery
    into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392,
    no. 6795, eaea6343, AAAS, 2026, doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>.
  short: B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L.
    Weiss, F.K. Schur, M. Loose, Science 392 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-04-28T13:29:05Z
day: '16'
department:
- _id: MaLo
- _id: FlSc
- _id: GradSch
- _id: EM-Fac
doi: 10.1126/science.aea6343
ec_funded: 1
external_id:
  pmid:
  - '41990175'
intvolume: '       392'
issue: '6795'
language:
- iso: eng
month: '04'
oa_version: None
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: bd980d18-d553-11ed-ba76-ceaa645c97eb
  grant_number: '101076260'
  name: A molecular atlas of Actin filament IDentities in the cell motility machinery
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Repurposing of a DNA segregation machinery into a cytoskeletal system controlling
  cell shape
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21755'
abstract:
- lang: eng
  text: Tropical shallow clouds are a major source of uncertainty in Earth's climate
    sensitivity, especially through their spatial arrangement, which global climate
    models do not represent. Efforts to understand their organization have partly
    relied on classifying observed scenes, identifying four patterns as archetypal
    regimes. Here we analyze geostationary satellite imagery of the western tropical
    Atlantic using the L‐function, a tool based on point pattern theory that quantifies
    cloud organization across spatial scales. Classical examples of the four patterns
    show distinct L‐function fingerprints, revealing their characteristic clustering
    and regularity scales and aiding physical interpretation. Yet, when evaluating
    many scenes at fixed spatial scales, the L‐function distribution lacks the distinct
    modes expected from discrete regimes. This is corroborated by analyses of other
    organization indices employing diverse approaches, from inter‐cloud nearest‐neighbor
    distances to fractal analysis. Implications for the parameterization of mesoscale
    cloud organization in climate models are discussed.
acknowledgement: GB was supported by an ICTP Postdoctoral Research Fellowship Agreement.
  GM was supported by the CNRS. AC was supported by the European Union's Horizon 2020
  research and innovation programme Marie Sklodowska-Curie Grant agreement No 101034413.
  LJF acknowledges funding from the NERC Doctoral Training Partnership in Environmental
  Research Grant NE/S007474/1. We thank three anonymous reviewers and Jiawei Bao for
  their insightful comments, which greatly improved this manuscript.
article_number: e2025GL119921
article_processing_charge: Yes
article_type: original
author:
- first_name: Giovanni
  full_name: Biagioli, Giovanni
  last_name: Biagioli
- first_name: Giulio
  full_name: Mandorli, Giulio
  last_name: Mandorli
- first_name: Lilli Johanna
  full_name: Freischem, Lilli Johanna
  last_name: Freischem
- first_name: Alejandro
  full_name: Casallas Garcia, Alejandro
  id: 92081129-2d75-11ef-a48d-b04dd7a2385a
  last_name: Casallas Garcia
  orcid: 0000-0002-1988-5035
- first_name: Adrian Mark
  full_name: Tompkins, Adrian Mark
  last_name: Tompkins
citation:
  ama: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. Spatial
    patterns of shallow clouds: Challenging the concept of defined regimes. <i>Geophysical
    Research Letters</i>. 2026;53(8). doi:<a href="https://doi.org/10.1029/2025gl119921">10.1029/2025gl119921</a>'
  apa: 'Biagioli, G., Mandorli, G., Freischem, L. J., Casallas Garcia, A., &#38; Tompkins,
    A. M. (2026). Spatial patterns of shallow clouds: Challenging the concept of defined
    regimes. <i>Geophysical Research Letters</i>. Wiley. <a href="https://doi.org/10.1029/2025gl119921">https://doi.org/10.1029/2025gl119921</a>'
  chicago: 'Biagioli, Giovanni, Giulio Mandorli, Lilli Johanna Freischem, Alejandro
    Casallas Garcia, and Adrian Mark Tompkins. “Spatial Patterns of Shallow Clouds:
    Challenging the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>.
    Wiley, 2026. <a href="https://doi.org/10.1029/2025gl119921">https://doi.org/10.1029/2025gl119921</a>.'
  ieee: 'G. Biagioli, G. Mandorli, L. J. Freischem, A. Casallas Garcia, and A. M.
    Tompkins, “Spatial patterns of shallow clouds: Challenging the concept of defined
    regimes,” <i>Geophysical Research Letters</i>, vol. 53, no. 8. Wiley, 2026.'
  ista: 'Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. 2026.
    Spatial patterns of shallow clouds: Challenging the concept of defined regimes.
    Geophysical Research Letters. 53(8), e2025GL119921.'
  mla: 'Biagioli, Giovanni, et al. “Spatial Patterns of Shallow Clouds: Challenging
    the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>, vol. 53,
    no. 8, e2025GL119921, Wiley, 2026, doi:<a href="https://doi.org/10.1029/2025gl119921">10.1029/2025gl119921</a>.'
  short: G. Biagioli, G. Mandorli, L.J. Freischem, A. Casallas Garcia, A.M. Tompkins,
    Geophysical Research Letters 53 (2026).
date_created: 2026-04-21T06:04:41Z
date_published: 2026-04-28T00:00:00Z
date_updated: 2026-04-28T13:35:53Z
day: '28'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1029/2025gl119921
ec_funded: 1
file:
- access_level: open_access
  checksum: 2cd4ae120b14b244f5b2f50eaae0efc1
  content_type: application/pdf
  creator: acasalla
  date_created: 2026-04-21T06:07:22Z
  date_updated: 2026-04-21T06:07:22Z
  file_id: '21756'
  file_name: Gio_Casallas_2026.pdf
  file_size: 1544417
  relation: main_file
  success: 1
file_date_updated: 2026-04-21T06:07:22Z
has_accepted_license: '1'
intvolume: '        53'
issue: '8'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Geophysical Research Letters
publication_identifier:
  eissn:
  - 1944-8007
  issn:
  - 0094-8276
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spatial patterns of shallow clouds: Challenging the concept of defined regimes'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21752'
abstract:
- lang: eng
  text: Epithelial tissues function as multicellular communities that preserve tissue
    integrity while adapting to diverse environmental stresses by altering cell behaviors.
    A striking manifestation of such adaptability is cell plasticity, the ability
    of differentiated cells to revert to stem-like states or adopt alternative fates.
    Once considered rare and confined to highly regenerative species, cell plasticity
    is now recognized across the metazoan tree. In early-branching animals such as
    sponges and cnidarians, transdifferentiation and dedifferentiation are integral
    to life-cycle transitions and regeneration, whereas in more complex organisms,
    these processes typically emerge under stress, including stem cell loss or environmental
    perturbations. Here, we examine epithelial cell plasticity through evolutionary,
    cellular, and molecular perspectives. Focusing on the intestinal epithelium, we
    explore findings from mammalian and Drosophila models showing that progenitors
    and even terminally differentiated cells can dedifferentiate in response to external
    stimuli that disrupt homeostasis, such as pathogen infection and nutrient fluctuations.
    We further discuss conserved mechanisms involving intercellular signaling (e.g.,
    Notch, EGFR, and JAK-STAT) and chromatin states primed for reprogramming, modulated
    by metabolic cues. Together, these insights position cell plasticity as an ancient
    environmental adaptation strategy, shaped by conserved molecular toolkits and
    refined by species- and cell lineage-specific innovations.
acknowledgement: This work was supported by JSPS/MEXT KAKENHI (grant numbers JP22J01430
  to H.N., JP23H04696, JP23K24025, JP25H02543, JP25K02406 to Y.N.), JST FOREST Program
  JPMJFR233E (Y.N.), The Cell Science Research Foundation (Y.N.), and Takeda Science
  Foundation (Y.N.).
article_number: '103670'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Hiroki
  full_name: Nagai, Hiroki
  id: 608df3e6-e2ab-11ed-8890-c9318cec7da4
  last_name: Nagai
  orcid: 0000-0003-1671-9434
- first_name: Yu Ichiro
  full_name: Nakajima, Yu Ichiro
  last_name: Nakajima
citation:
  ama: 'NAGAI H, Nakajima YI. Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms. <i>Seminars in Cell and Developmental Biology</i>.
    2026;179-180. doi:<a href="https://doi.org/10.1016/j.semcdb.2026.103670">10.1016/j.semcdb.2026.103670</a>'
  apa: 'NAGAI, H., &#38; Nakajima, Y. I. (2026). Epithelial cell plasticity in metazoans:
    Evolutionary insights into roles and mechanisms. <i>Seminars in Cell and Developmental
    Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2026.103670">https://doi.org/10.1016/j.semcdb.2026.103670</a>'
  chicago: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in
    Metazoans: Evolutionary Insights into Roles and Mechanisms.” <i>Seminars in Cell
    and Developmental Biology</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.semcdb.2026.103670">https://doi.org/10.1016/j.semcdb.2026.103670</a>.'
  ieee: 'H. NAGAI and Y. I. Nakajima, “Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms,” <i>Seminars in Cell and Developmental Biology</i>,
    vol. 179–180. Elsevier, 2026.'
  ista: 'NAGAI H, Nakajima YI. 2026. Epithelial cell plasticity in metazoans: Evolutionary
    insights into roles and mechanisms. Seminars in Cell and Developmental Biology.
    179–180, 103670.'
  mla: 'NAGAI, HIROKI, and Yu Ichiro Nakajima. “Epithelial Cell Plasticity in Metazoans:
    Evolutionary Insights into Roles and Mechanisms.” <i>Seminars in Cell and Developmental
    Biology</i>, vol. 179–180, 103670, Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.semcdb.2026.103670">10.1016/j.semcdb.2026.103670</a>.'
  short: H. NAGAI, Y.I. Nakajima, Seminars in Cell and Developmental Biology 179–180
    (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:49Z
date_published: 2026-05-01T00:00:00Z
date_updated: 2026-04-28T14:11:13Z
day: '01'
ddc:
- '570'
department:
- _id: XiFe
doi: 10.1016/j.semcdb.2026.103670
file:
- access_level: open_access
  checksum: 0a0929a045d0cbd964297768833c14ae
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T13:58:47Z
  date_updated: 2026-04-28T13:58:47Z
  file_id: '21775'
  file_name: 2026_SeminarsCellDevBiology_Nagai.pdf
  file_size: 1306613
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T13:58:47Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
publication: Seminars in Cell and Developmental Biology
publication_identifier:
  eissn:
  - 1096-3634
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Epithelial cell plasticity in metazoans: Evolutionary insights into roles
  and mechanisms'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 179-180
year: '2026'
...
