---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20218'
abstract:
- lang: eng
  text: Humanity has long sought inspiration from nature to innovate materials and
    devices. As science advances, nature-inspired materials are becoming part of our
    lives. Animate materials, characterized by their activity, adaptability, and autonomy,
    emulate properties of living systems. While only biological materials fully embody
    these principles, artificial versions are advancing rapidly, promising transformative
    impacts in the circular economy, health and climate resilience within a generation.
    This roadmap presents authoritative perspectives on animate materials across different
    disciplines and scales, highlighting their interdisciplinary nature and potential
    applications in diverse fields including nanotechnology, robotics and the built
    environment. It underscores the need for concerted efforts to address shared challenges
    such as complexity management, scalability, evolvability, interdisciplinary collaboration,
    and ethical and environmental considerations. The framework defined by classifying
    materials based on their level of animacy can guide this emerging field to encourage
    cooperation and responsible development. By unravelling the mysteries of living
    matter and leveraging its principles, we can design materials and systems that
    will transform our world in a more sustainable manner.
acknowledgement: "Living Architecture is Funded by the EU Horizon 2020 Future Emerging
  Technologies Open programme (2016–2019) Grant Agreement 686585 a consortium of 6
  collaborating institutions—Newcastle University, University of Trento, University
  of the West of England, Spanish National Research Council, Explora Biotech and Liquifer
  Systems Group.\r\n\r\nThe Active Living Infrastructure: Controlled Environment (ALICE)
  project is funded by an EU Innovation Award for the development of a bio-digital
  ‘brick’ prototype, a collaboration between Newcastle University, Translating Nature,
  and the University of the West of England (2019–2021) under EU Grant Agreement No.
  851246.\r\n\r\nMicrobial Hydroponics: Circular Sustainable Electrobiosynthesis (Mi-Hy)
  is Funded by the European Union under Grant Agreement Number 101114746, which is
  a collaboration between Beneficiaries, KU Leuven (Belgium), the University of Southampton
  (UK), SONY Computer Science Laboratory (France), BioFaction KG (Austria), Spanish
  National Research Council (Spain), and Associated Partners, the University of the
  West of England (UK) and University of Southampton (UK). Mi-Hy is also supported
  through the interdisciplinary KU Leuven Institute for Cultural Heritage (HERKUL)."
article_number: '333501'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Volpe, Giorgio
  last_name: Volpe
- first_name: Nuno A.M.
  full_name: Araújo, Nuno A.M.
  last_name: Araújo
- first_name: Maria
  full_name: Guix, Maria
  last_name: Guix
- first_name: Mark
  full_name: Miodownik, Mark
  last_name: Miodownik
- first_name: Nicolas
  full_name: Martin, Nicolas
  last_name: Martin
- first_name: Laura
  full_name: Alvarez, Laura
  last_name: Alvarez
- first_name: Juliane
  full_name: Simmchen, Juliane
  last_name: Simmchen
- first_name: Roberto Di
  full_name: Leonardo, Roberto Di
  last_name: Leonardo
- first_name: Nicola
  full_name: Pellicciotta, Nicola
  last_name: Pellicciotta
- first_name: Quentin
  full_name: Martinet, Quentin
  id: b37485a8-d343-11eb-a0e9-df8c484ef8ab
  last_name: Martinet
  orcid: 0000-0002-2916-6632
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
- first_name: Wai Kit
  full_name: Ng, Wai Kit
  last_name: Ng
- first_name: Dhruv
  full_name: Saxena, Dhruv
  last_name: Saxena
- first_name: Riccardo
  full_name: Sapienza, Riccardo
  last_name: Sapienza
- first_name: Sara
  full_name: Nadine, Sara
  last_name: Nadine
- first_name: João F.
  full_name: Mano, João F.
  last_name: Mano
- first_name: Reza
  full_name: Mahdavi, Reza
  last_name: Mahdavi
- first_name: Caroline
  full_name: Beck Adiels, Caroline
  last_name: Beck Adiels
- first_name: Joe
  full_name: Forth, Joe
  last_name: Forth
- first_name: Christian
  full_name: Santangelo, Christian
  last_name: Santangelo
- first_name: Stefano
  full_name: Palagi, Stefano
  last_name: Palagi
- first_name: Ji Min
  full_name: Seok, Ji Min
  last_name: Seok
- first_name: Victoria A.
  full_name: Webster-Wood, Victoria A.
  last_name: Webster-Wood
- first_name: Shuhong
  full_name: Wang, Shuhong
  last_name: Wang
- first_name: Lining
  full_name: Yao, Lining
  last_name: Yao
- first_name: Amirreza
  full_name: Aghakhani, Amirreza
  last_name: Aghakhani
- first_name: Thomas
  full_name: Barois, Thomas
  last_name: Barois
- first_name: Hamid
  full_name: Kellay, Hamid
  last_name: Kellay
- first_name: Corentin
  full_name: Coulais, Corentin
  last_name: Coulais
- first_name: Martin
  full_name: Van Hecke, Martin
  last_name: Van Hecke
- first_name: Christopher J.
  full_name: Pierce, Christopher J.
  last_name: Pierce
- first_name: Tianyu
  full_name: Wang, Tianyu
  last_name: Wang
- first_name: Baxi
  full_name: Chong, Baxi
  last_name: Chong
- first_name: Daniel I.
  full_name: Goldman, Daniel I.
  last_name: Goldman
- first_name: Andreagiovanni
  full_name: Reina, Andreagiovanni
  last_name: Reina
- first_name: Vito
  full_name: Trianni, Vito
  last_name: Trianni
- first_name: Giovanni
  full_name: Volpe, Giovanni
  last_name: Volpe
- first_name: Richard
  full_name: Beckett, Richard
  last_name: Beckett
- first_name: Sean P.
  full_name: Nair, Sean P.
  last_name: Nair
- first_name: Rachel
  full_name: Armstrong, Rachel
  last_name: Armstrong
citation:
  ama: 'Volpe G, Araújo NAM, Guix M, et al. Roadmap for animate matter. <i>Journal
    of Physics: Condensed Matter</i>. 2025;37(33). doi:<a href="https://doi.org/10.1088/1361-648X/adebd3">10.1088/1361-648X/adebd3</a>'
  apa: 'Volpe, G., Araújo, N. A. M., Guix, M., Miodownik, M., Martin, N., Alvarez,
    L., … Armstrong, R. (2025). Roadmap for animate matter. <i>Journal of Physics:
    Condensed Matter</i>. IOP Publishing. <a href="https://doi.org/10.1088/1361-648X/adebd3">https://doi.org/10.1088/1361-648X/adebd3</a>'
  chicago: 'Volpe, Giorgio, Nuno A.M. Araújo, Maria Guix, Mark Miodownik, Nicolas
    Martin, Laura Alvarez, Juliane Simmchen, et al. “Roadmap for Animate Matter.”
    <i>Journal of Physics: Condensed Matter</i>. IOP Publishing, 2025. <a href="https://doi.org/10.1088/1361-648X/adebd3">https://doi.org/10.1088/1361-648X/adebd3</a>.'
  ieee: 'G. Volpe <i>et al.</i>, “Roadmap for animate matter,” <i>Journal of Physics:
    Condensed Matter</i>, vol. 37, no. 33. IOP Publishing, 2025.'
  ista: 'Volpe G, Araújo NAM, Guix M, Miodownik M, Martin N, Alvarez L, Simmchen J,
    Leonardo RD, Pellicciotta N, Martinet Q, Palacci JA, Ng WK, Saxena D, Sapienza
    R, Nadine S, Mano JF, Mahdavi R, Beck Adiels C, Forth J, Santangelo C, Palagi
    S, Seok JM, Webster-Wood VA, Wang S, Yao L, Aghakhani A, Barois T, Kellay H, Coulais
    C, Van Hecke M, Pierce CJ, Wang T, Chong B, Goldman DI, Reina A, Trianni V, Volpe
    G, Beckett R, Nair SP, Armstrong R. 2025. Roadmap for animate matter. Journal
    of Physics: Condensed Matter. 37(33), 333501.'
  mla: 'Volpe, Giorgio, et al. “Roadmap for Animate Matter.” <i>Journal of Physics:
    Condensed Matter</i>, vol. 37, no. 33, 333501, IOP Publishing, 2025, doi:<a href="https://doi.org/10.1088/1361-648X/adebd3">10.1088/1361-648X/adebd3</a>.'
  short: 'G. Volpe, N.A.M. Araújo, M. Guix, M. Miodownik, N. Martin, L. Alvarez, J.
    Simmchen, R.D. Leonardo, N. Pellicciotta, Q. Martinet, J.A. Palacci, W.K. Ng,
    D. Saxena, R. Sapienza, S. Nadine, J.F. Mano, R. Mahdavi, C. Beck Adiels, J. Forth,
    C. Santangelo, S. Palagi, J.M. Seok, V.A. Webster-Wood, S. Wang, L. Yao, A. Aghakhani,
    T. Barois, H. Kellay, C. Coulais, M. Van Hecke, C.J. Pierce, T. Wang, B. Chong,
    D.I. Goldman, A. Reina, V. Trianni, G. Volpe, R. Beckett, S.P. Nair, R. Armstrong,
    Journal of Physics: Condensed Matter 37 (2025).'
date_created: 2025-08-24T22:01:30Z
date_published: 2025-08-18T00:00:00Z
date_updated: 2026-08-12T14:00:12Z
day: '18'
ddc:
- '530'
department:
- _id: JePa
doi: 10.1088/1361-648X/adebd3
external_id:
  arxiv:
  - '2407.10623'
  isi:
  - '001550090200001'
file:
- access_level: open_access
  checksum: 7309274f78bed785b158bd290337f456
  content_type: application/pdf
  creator: dernst
  date_created: 2025-09-02T07:22:48Z
  date_updated: 2025-09-02T07:22:48Z
  file_id: '20271'
  file_name: 2025_CondensedMatter_Volpe.pdf
  file_size: 8997829
  relation: main_file
  success: 1
file_date_updated: 2025-09-02T07:22:48Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '33'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: 'Journal of Physics: Condensed Matter'
publication_identifier:
  eissn:
  - 1361-648X
  issn:
  - 0953-8984
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Roadmap for animate matter
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20453'
abstract:
- lang: eng
  text: 'Magnetotropic susceptibility is the thermodynamic coefficient that maps the
    curvature of free energy with respect to an applied magnetic field orientation,
    providing a means to quantify the magnetic anisotropy of a crystal. In this context,
    non-linear magnetic torque behavior has been reported in FePS3, motivating the
    investigation of similar non-linear characteristics in its magnetotropic susceptibility.
    In this work, we derive the non-linear magnetotropic susceptibility expressions
    for FePS3 in both ac*-and bc*-planes using complementary approaches: by taking
    the first derivative of torque and through the formal calculation of the magnetotropic
    susceptibility. Higher-order terms in the magnetization are included, and the
    final equations are obtained by applying symmetry constraints imposed by the C2h
    point group of the material. We analyze the behavior of the resulting non-linear
    expressions and identify the contributions of each parameter. Our theoretical
    results show good agreement with preliminary, unpublished experimental data, offering
    meaningful guidance for ongoing and future experimental work.'
acknowledgement: We thank Kimberly A. Modic for her support and discussions regarding
  the technique in the context of a project indirectly related to, but distinct from,
  the present work. We also thank Brad J. Ramshaw and Arkady Shekhter for scientific
  discussions not directly related to this study, but whose insights proved helpful.
  We are grateful to Valeska Zambra, Amit Nathwani, Hamza Nasir, and Tayyaba Hussain
  for informal discussions on various aspects of the technique, and to Naoya Iwahara
  for his thoughtful and constructive feedback. The experimental curve shown in figures
  3(b) and 6, from the Thermodynamics of Quantum Materials (TQM) group at ISTA, was
  measured by Muhammad Nauman for an unrelated project. We thank Kimberly Modic for
  granting access to the laboratory facilities. Je Geun Park provided the crystal
  used for that measurement via Younjung Jo, whose contribution we gratefully acknowledge.
  Institutional support from the Institute of Science and Technology Austria (ISTA)
  is also gratefully acknowledged.
article_number: '405801'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Hamza
  full_name: Farooq, Hamza
  last_name: Farooq
- first_name: Muhammad
  full_name: Nauman, Muhammad
  id: 32c21954-2022-11eb-9d5f-af9f93c24e71
  last_name: Nauman
  orcid: 0000-0002-2111-4846
citation:
  ama: 'Farooq H, Nauman M. Non-linear magnetotropic susceptibility in FePS3. <i>Journal
    of Physics: Condensed Matter</i>. 2025;37(40). doi:<a href="https://doi.org/10.1088/1361-648X/ae0913">10.1088/1361-648X/ae0913</a>'
  apa: 'Farooq, H., &#38; Nauman, M. (2025). Non-linear magnetotropic susceptibility
    in FePS3. <i>Journal of Physics: Condensed Matter</i>. IOP Publishing. <a href="https://doi.org/10.1088/1361-648X/ae0913">https://doi.org/10.1088/1361-648X/ae0913</a>'
  chicago: 'Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility
    in FePS3.” <i>Journal of Physics: Condensed Matter</i>. IOP Publishing, 2025.
    <a href="https://doi.org/10.1088/1361-648X/ae0913">https://doi.org/10.1088/1361-648X/ae0913</a>.'
  ieee: 'H. Farooq and M. Nauman, “Non-linear magnetotropic susceptibility in FePS3,”
    <i>Journal of Physics: Condensed Matter</i>, vol. 37, no. 40. IOP Publishing,
    2025.'
  ista: 'Farooq H, Nauman M. 2025. Non-linear magnetotropic susceptibility in FePS3.
    Journal of Physics: Condensed Matter. 37(40), 405801.'
  mla: 'Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility
    in FePS3.” <i>Journal of Physics: Condensed Matter</i>, vol. 37, no. 40, 405801,
    IOP Publishing, 2025, doi:<a href="https://doi.org/10.1088/1361-648X/ae0913">10.1088/1361-648X/ae0913</a>.'
  short: 'H. Farooq, M. Nauman, Journal of Physics: Condensed Matter 37 (2025).'
corr_author: '1'
date_created: 2025-10-12T22:01:26Z
date_published: 2025-10-06T00:00:00Z
date_updated: 2026-08-12T14:00:34Z
day: '06'
ddc:
- '530'
department:
- _id: KiMo
doi: 10.1088/1361-648X/ae0913
external_id:
  isi:
  - '001585824100001'
  pmid:
  - '40967257'
file:
- access_level: open_access
  checksum: b182856a5a655496e149afa49ec464f3
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T06:34:15Z
  date_updated: 2025-10-13T06:34:15Z
  file_id: '20458'
  file_name: 2025_JourPhysicsCondMatter_Farooq.pdf
  file_size: 1709516
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T06:34:15Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: 'Journal of Physics: Condensed Matter'
publication_identifier:
  eissn:
  - 1361-648X
  issn:
  - 0953-8984
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-linear magnetotropic susceptibility in FePS3
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2025'
...
---
OA_type: closed access
_id: '20219'
abstract:
- lang: eng
  text: Reproduction is a fundamental biological process, with organisms reproducing
    sexually, asexually, and, in some cases, utilizing both modes of reproduction
    within the same population. Does the ability to reproduce through a combination
    of asexual and sexual modes offer an evolutionary advantage over relying on either
    mode alone? Here, we introduce an empirically driven theoretical model to examine
    the dynamics and interplay between sexual and asexual reproduction in stick insect
    populations. We analyse it using a novel phase transition approach and corroborate
    it using published experimental data. We find that the presence of males can either
    increase or decrease the overall population size. However, maintaining an optimal
    ratio of parthenogenetic to sexual reproduction is crucial for male resilience,
    effectively delaying male extinction. Conversely, extreme levels of parthenogenetic
    reproduction—whether too high or too low—can lead to male extinction, emphasizing
    the need for a balanced number of virgin females to ensure the persistence of
    males. Our model also explains male absence in Carausius morosus and persistence
    in Extatosoma tiaratum. Our findings provide valuable insights into the interplay
    of reproductive strategies and contribute to broader discussions on the transitions
    between sexual and asexual reproduction.
acknowledgement: We acknowledge Prof. Uri Alon for introducing us to the topic of
  systems biology during the graduate course at the Weizmann Institute of Science,
  whose insights and teachings have greatly inspired this work.
article_number: '20250202'
article_processing_charge: No
article_type: original
author:
- first_name: Oran
  full_name: Ayalon, Oran
  last_name: Ayalon
- first_name: Harikrishnan
  full_name: Rajendran, Harikrishnan
  id: 876b6b34-8ff4-11ec-97c9-8d95a7aae416
  last_name: Rajendran
citation:
  ama: Ayalon O, Rajendran H. Interplay of asexual and sexual reproduction in bifunctional
    insects. <i>Journal of the Royal Society Interface</i>. 2025;22(229). doi:<a href="https://doi.org/10.1098/rsif.2025.0202">10.1098/rsif.2025.0202</a>
  apa: Ayalon, O., &#38; Rajendran, H. (2025). Interplay of asexual and sexual reproduction
    in bifunctional insects. <i>Journal of the Royal Society Interface</i>. Royal
    Society. <a href="https://doi.org/10.1098/rsif.2025.0202">https://doi.org/10.1098/rsif.2025.0202</a>
  chicago: Ayalon, Oran, and Harikrishnan Rajendran. “Interplay of Asexual and Sexual
    Reproduction in Bifunctional Insects.” <i>Journal of the Royal Society Interface</i>.
    Royal Society, 2025. <a href="https://doi.org/10.1098/rsif.2025.0202">https://doi.org/10.1098/rsif.2025.0202</a>.
  ieee: O. Ayalon and H. Rajendran, “Interplay of asexual and sexual reproduction
    in bifunctional insects,” <i>Journal of the Royal Society Interface</i>, vol.
    22, no. 229. Royal Society, 2025.
  ista: Ayalon O, Rajendran H. 2025. Interplay of asexual and sexual reproduction
    in bifunctional insects. Journal of the Royal Society Interface. 22(229), 20250202.
  mla: Ayalon, Oran, and Harikrishnan Rajendran. “Interplay of Asexual and Sexual
    Reproduction in Bifunctional Insects.” <i>Journal of the Royal Society Interface</i>,
    vol. 22, no. 229, 20250202, Royal Society, 2025, doi:<a href="https://doi.org/10.1098/rsif.2025.0202">10.1098/rsif.2025.0202</a>.
  short: O. Ayalon, H. Rajendran, Journal of the Royal Society Interface 22 (2025).
corr_author: '1'
date_created: 2025-08-24T22:01:30Z
date_published: 2025-08-13T00:00:00Z
date_updated: 2026-08-12T14:09:20Z
day: '13'
department:
- _id: SyCr
doi: 10.1098/rsif.2025.0202
external_id:
  isi:
  - '001548084900001'
  pmid:
  - '40799050'
intvolume: '        22'
isi: 1
issue: '229'
language:
- iso: eng
month: '08'
oa_version: None
pmid: 1
publication: Journal of the Royal Society Interface
publication_identifier:
  eissn:
  - 1742-5662
  issn:
  - 1742-5689
publication_status: published
publisher: Royal Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interplay of asexual and sexual reproduction in bifunctional insects
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19762'
abstract:
- lang: eng
  text: The cerebral cortex must contain the appropriate numbers of neurons in each
    layer to acquire its proper functional organization. Accordingly, neurogenesis
    requires precise regulation along development. Cortical neurons are made either
    directly by Radial Glia Cells (RGCs) that self- consume, or indirectly from RGCs
    via Intermediate Progenitor Cells (IPCs) and largely preserving the RGC pool.
    According to the standing model of cortical development, Direct Neurogenesis predominates
    at early stages of development, and progressively shifts to Indirect Neurogenesis,
    which predominates at late stages. However, neurogenesis at early stages should
    be compatible with RGC amplification, and neurogenesis at late stages needs to
    involve RGC consumption, which seems in conflict with the standing model. Here
    we studied the modes of neurogenesis along cortical development using multiple
    approaches, including birthdating, live imaging and MADM clone labeling. Contrary
    to the established dogma, our data show that Indirect Neurogenesis clearly predominates
    at early developmental stages, gradually shifting to Direct Neurogenesis at late
    stages. These findings challenge the current model of cortical neurogenesis, and
    prompt a re-evaluation of previous and ongoing work about the genetic and molecular
    mechanisms regulating this process.
acknowledgement: "We thank A. Iñigo for assistance with imaging, and members of the
  Borrell and Herrera labs for\r\ninsightful discussions and critical reading of the
  manuscript. Funding to our lab members was\r\nprovided by the Spanish Research Agency
  (AEI): FPI contract (BES-2016-077737) to L.dV.A., FPI SO contract (SEV-2017-0723-18-1)
  to A.E., JdC-Incorporación contract (IJC2020-044653-I) to V.F., and JAE-Intro fellowship
  (JAEICU23EX_0071) to I.C., as well as by La Caixa Foundation: La Caixa-Severo Ochoa
  fellowship (E-03-2016-0557140) to S.A., INPhINIT-Retaining fellowship (LCF/BQ/DR21/11880012)
  to E.F.O., INPhINIT-Incoming fellowship (LCF/BQ/DI22/11940006) to E.N., and Junior
  Leader-Retaining grant to A.C. (LCF/BQ/PR23/11980051). Work was supported by grants
  from FWF (SFB F78) to S.H.; AEI (PID2021-125618NB-I00) and European Research Council
  (101118729) to V.B., who also acknowledges financial support from AEI through the
  “Severo Ochoa” Programme for Centers of Excellence in R&D (CEX2021-001165-S)."
article_processing_charge: No
author:
- first_name: Adrián
  full_name: Cárdenas, Adrián
  last_name: Cárdenas
- first_name: Irem
  full_name: Çelik, Irem
  last_name: Çelik
- first_name: Alexandre
  full_name: Espinós, Alexandre
  last_name: Espinós
- first_name: Carmen
  full_name: Streicher, Carmen
  id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
  last_name: Streicher
- first_name: Lara
  full_name: López-González, Lara
  last_name: López-González
- first_name: Lucia
  full_name: del-Valle-Anton, Lucia
  last_name: del-Valle-Anton
- first_name: Virginia
  full_name: Fernández, Virginia
  last_name: Fernández
- first_name: Salma
  full_name: Amin, Salma
  last_name: Amin
- first_name: Enrico
  full_name: Negri, Enrico
  last_name: Negri
- first_name: Eduardo Fernández
  full_name: Ortuño, Eduardo Fernández
  last_name: Ortuño
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Víctor
  full_name: Borrell, Víctor
  last_name: Borrell
biorxivid: 1
citation:
  ama: Cárdenas A, Çelik I, Espinós A, et al. Early indirect neurogenesis transitions
    to late direct neurogenesis in mouse cerebral cortex development. <i>bioRxiv</i>.
    doi:<a href="https://doi.org/10.1101/2025.05.22.655488">10.1101/2025.05.22.655488</a>
  apa: Cárdenas, A., Çelik, I., Espinós, A., Streicher, C., López-González, L., del-Valle-Anton,
    L., … Borrell, V. (n.d.). Early indirect neurogenesis transitions to late direct
    neurogenesis in mouse cerebral cortex development. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2025.05.22.655488">https://doi.org/10.1101/2025.05.22.655488</a>
  chicago: Cárdenas, Adrián, Irem Çelik, Alexandre Espinós, Carmen Streicher, Lara
    López-González, Lucia del-Valle-Anton, Virginia Fernández, et al. “Early Indirect
    Neurogenesis Transitions to Late Direct Neurogenesis in Mouse Cerebral Cortex
    Development.” <i>BioRxiv</i>, n.d. <a href="https://doi.org/10.1101/2025.05.22.655488">https://doi.org/10.1101/2025.05.22.655488</a>.
  ieee: A. Cárdenas <i>et al.</i>, “Early indirect neurogenesis transitions to late
    direct neurogenesis in mouse cerebral cortex development,” <i>bioRxiv</i>. .
  ista: Cárdenas A, Çelik I, Espinós A, Streicher C, López-González L, del-Valle-Anton
    L, Fernández V, Amin S, Negri E, Ortuño EF, Hippenmeyer S, Borrell V. Early indirect
    neurogenesis transitions to late direct neurogenesis in mouse cerebral cortex
    development. bioRxiv, <a href="https://doi.org/10.1101/2025.05.22.655488">10.1101/2025.05.22.655488</a>.
  mla: Cárdenas, Adrián, et al. “Early Indirect Neurogenesis Transitions to Late Direct
    Neurogenesis in Mouse Cerebral Cortex Development.” <i>BioRxiv</i>, doi:<a href="https://doi.org/10.1101/2025.05.22.655488">10.1101/2025.05.22.655488</a>.
  short: A. Cárdenas, I. Çelik, A. Espinós, C. Streicher, L. López-González, L. del-Valle-Anton,
    V. Fernández, S. Amin, E. Negri, E.F. Ortuño, S. Hippenmeyer, V. Borrell, BioRxiv
    (n.d.).
date_created: 2025-05-29T10:45:55Z
date_published: 2025-05-23T00:00:00Z
date_updated: 2026-08-13T07:18:38Z
day: '23'
department:
- _id: SiHi
doi: 10.1101/2025.05.22.655488
external_id:
  biorxivid:
  - 10.1101/2025.05.22.655488
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.05.22.655488
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F7805
  name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
    Mechanisms of Neural Stem Cell Lineage Progression
publication: bioRxiv
publication_status: submitted
status: public
title: Early indirect neurogenesis transitions to late direct neurogenesis in mouse
  cerebral cortex development
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19717'
abstract:
- lang: eng
  text: Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the
    cerebral cortex through incompletely understood processes. Herein, we combine
    Mosaic Analysis with Double Markers (MADM)-based clonal analysis at embryonic
    days 12.5 and 13.5 with early postnatal callosal tracing to reveal a lineage progression
    that challenges the inside-outside model of cortical development and the conventional
    view of an invariable sequence of asymmetric neurogenic divisions. Our data demonstrate
    that early multipotent RGPs generate all extra-telencephalic (ET) and intra-telencephalic
    (IT) PNs across all layers through parallel sublineages and the random specification,
    during the earliest neurogenic divisions, of fate-restricted daughter RGPs. While
    the neuronal production of the parental multipotent RGPs consists of small ET-PN
    or IT-PN outputs, fate-restricted RGPs produce larger translaminar outputs spanning
    deep and upper layers of only IT-PNs, the predominant mammalian PN subtype. We
    further show that the emergence of IT-PN fate-restricted RGPs also leads to quantitatively
    and temporally stereotyped neurogenesis population-wise.
acknowledgement: "We thank M. Caouyette for the plasmid construction for Pou3f1 overexpression;
  C. Varela747 Martínez for help with the code for graphical analysis; all members
  from the Nieto’s lab for\r\ncomment on the manuscript, specially to F. Martín for
  the insightful discussions;J.C. Oliveros\r\nand J.A. García from the computational
  service of the CNB for help with the analysis of\r\nRNAseq dataset, C.O. Sorzano
  for the help with statistical analysis, and the service of\r\nAdvance Optical Microscopy
  of the CNB for their technical advice.\r\nI.V.M holds a fellowship funded by MCICIU
  (PRE-2018-083376), the work was funded by\r\nPID2020-112831GB-I00 funded by MCIN/AEI
  /10.13039/501100011033.\r\n"
article_processing_charge: No
author:
- first_name: I
  full_name: Varela-Martínez, I
  last_name: Varela-Martínez
- first_name: Ana
  full_name: Villalba Requena, Ana
  id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
  last_name: Villalba Requena
  orcid: 0000-0002-5615-5277
- first_name: J.
  full_name: Garcia-Marqués, J.
  last_name: Garcia-Marqués
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: M.
  full_name: Nieto, M.
  last_name: Nieto
citation:
  ama: Varela-Martínez I, Villalba Requena A, Garcia-Marqués J, Hippenmeyer S, Nieto
    M. Early emergence of projection-subtype fate-restricted radial glial progenitors
    orchestrates neocortical neurogenesis. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2025.05.07.652665">10.1101/2025.05.07.652665</a>
  apa: Varela-Martínez, I., Villalba Requena, A., Garcia-Marqués, J., Hippenmeyer,
    S., &#38; Nieto, M. (n.d.). Early emergence of projection-subtype fate-restricted
    radial glial progenitors orchestrates neocortical neurogenesis. <i>bioRxiv</i>.
    <a href="https://doi.org/10.1101/2025.05.07.652665">https://doi.org/10.1101/2025.05.07.652665</a>
  chicago: Varela-Martínez, I, Ana Villalba Requena, J. Garcia-Marqués, Simon Hippenmeyer,
    and M. Nieto. “Early Emergence of Projection-Subtype Fate-Restricted Radial Glial
    Progenitors Orchestrates Neocortical Neurogenesis.” <i>BioRxiv</i>, n.d. <a href="https://doi.org/10.1101/2025.05.07.652665">https://doi.org/10.1101/2025.05.07.652665</a>.
  ieee: I. Varela-Martínez, A. Villalba Requena, J. Garcia-Marqués, S. Hippenmeyer,
    and M. Nieto, “Early emergence of projection-subtype fate-restricted radial glial
    progenitors orchestrates neocortical neurogenesis,” <i>bioRxiv</i>. .
  ista: Varela-Martínez I, Villalba Requena A, Garcia-Marqués J, Hippenmeyer S, Nieto
    M. Early emergence of projection-subtype fate-restricted radial glial progenitors
    orchestrates neocortical neurogenesis. bioRxiv, <a href="https://doi.org/10.1101/2025.05.07.652665">10.1101/2025.05.07.652665</a>.
  mla: Varela-Martínez, I., et al. “Early Emergence of Projection-Subtype Fate-Restricted
    Radial Glial Progenitors Orchestrates Neocortical Neurogenesis.” <i>BioRxiv</i>,
    doi:<a href="https://doi.org/10.1101/2025.05.07.652665">10.1101/2025.05.07.652665</a>.
  short: I. Varela-Martínez, A. Villalba Requena, J. Garcia-Marqués, S. Hippenmeyer,
    M. Nieto, BioRxiv (n.d.).
date_created: 2025-05-20T10:19:29Z
date_published: 2025-05-07T00:00:00Z
date_updated: 2026-08-13T07:16:48Z
day: '07'
department:
- _id: SiHi
doi: 10.1101/2025.05.07.652665
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.05.07.652665
month: '05'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: submitted
status: public
title: Early emergence of projection-subtype fate-restricted radial glial progenitors
  orchestrates neocortical neurogenesis
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19674'
abstract:
- lang: eng
  text: 'When examined through the lens of their residual streams, a puzzling property
    emerges in transformer networks: residual contributions (e.g., attention heads)
    sometimes specialize in specific tasks or input attributes. In this paper, we
    analyze this phenomenon in vision transformers, focusing on the spectral geometry
    of residuals, and explore its implications for modality alignment in vision-language
    models. First, we link it to the intrinsically low-dimensional structure of visual
    head representations, zooming into their principal components and showing that
    they encode specialized roles across a wide variety of input data distributions.
    Then, we analyze the effect of head specialization in multimodal models, focusing
    on how improved alignment between text and specialized heads impacts zero-shot
    classification performance. This specialization-performance link consistently
    holds across diverse pre-training data, network sizes, and objectives, demonstrating
    a powerful new mechanism for boosting zero-shot classification through targeted
    alignment. Ultimately, we translate these insights into actionable terms by introducing
    ResiDual, a technique for spectral alignment of the residual stream. Much like
    panning for gold, it lets the noise from irrelevant unit principal components
    (i.e., attributes) wash away to amplify task-relevant ones. Remarkably, this dual
    perspective on modality alignment yields fine-tuning level performance on different
    data distributions while modelling an extremely interpretable and parameter-efficient
    transformation, as we extensively show on 70 pre-trained network-dataset combinations
    (7 models, 10 datasets).'
acknowledgement: "The authors gratefully acknowledge Volkan Cevher for an insightful
  discussion about sparse recovery algorithms, Alex Smola for valuable feedback on
  the experiments, and Marco Baroni for an engaging conversation on the phenomenon
  of head specialization in NLP.\r\n"
article_number: '2411.00246'
article_processing_charge: No
arxiv: 1
author:
- first_name: Lorenzo
  full_name: Basile, Lorenzo
  last_name: Basile
- first_name: Valentino
  full_name: Maiorca, Valentino
  last_name: Maiorca
- first_name: Luca
  full_name: Bortolussi, Luca
  last_name: Bortolussi
- first_name: Emanuele
  full_name: Rodolà, Emanuele
  last_name: Rodolà
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
citation:
  ama: Basile L, Maiorca V, Bortolussi L, Rodolà E, Locatello F. ResiDual transformer
    alignment with spectral decomposition. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2411.00246">10.48550/arXiv.2411.00246</a>
  apa: Basile, L., Maiorca, V., Bortolussi, L., Rodolà, E., &#38; Locatello, F. (n.d.).
    ResiDual transformer alignment with spectral decomposition. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2411.00246">https://doi.org/10.48550/arXiv.2411.00246</a>
  chicago: Basile, Lorenzo, Valentino Maiorca, Luca Bortolussi, Emanuele Rodolà, and
    Francesco Locatello. “ResiDual Transformer Alignment with Spectral Decomposition.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2411.00246">https://doi.org/10.48550/arXiv.2411.00246</a>.
  ieee: L. Basile, V. Maiorca, L. Bortolussi, E. Rodolà, and F. Locatello, “ResiDual
    transformer alignment with spectral decomposition,” <i>arXiv</i>. .
  ista: Basile L, Maiorca V, Bortolussi L, Rodolà E, Locatello F. ResiDual transformer
    alignment with spectral decomposition. arXiv, 2411.00246.
  mla: Basile, Lorenzo, et al. “ResiDual Transformer Alignment with Spectral Decomposition.”
    <i>ArXiv</i>, 2411.00246, doi:<a href="https://doi.org/10.48550/arXiv.2411.00246">10.48550/arXiv.2411.00246</a>.
  short: L. Basile, V. Maiorca, L. Bortolussi, E. Rodolà, F. Locatello, ArXiv (n.d.).
date_created: 2025-05-11T22:02:41Z
date_published: 2025-04-14T00:00:00Z
date_updated: 2026-08-13T07:33:41Z
day: '14'
ddc:
- '000'
department:
- _id: FrLo
doi: 10.48550/arXiv.2411.00246
external_id:
  arxiv:
  - '2411.00246'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2411.00246
month: '04'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: ResiDual transformer alignment with spectral decomposition
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
_id: '20167'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "This work was supported by EMBO (ALTF 302-2019 to Niko Amin-Wetzel),
  the FWF\r\n(ESPRIT PR1054E140 to Niko Amin-Wetzel), the European Research Council\r\n(Advanced
  Grant 269058 to Mario de Bono) and Wellcome (209504/A/17/Z\r\nInvestigator Award
  to Mario de Bono). "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Hanna
  full_name: Schön, Hanna
  id: C8E17EDC-D7AA-11E9-B7B7-45ECE5697425
  last_name: Schön
citation:
  ama: Schön H. The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20167">10.15479/AT-ISTA-20167</a>
  apa: Schön, H. (2025). <i>The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs
    encoding GPCRs</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20167">https://doi.org/10.15479/AT-ISTA-20167</a>
  chicago: Schön, Hanna. “The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs
    Encoding GPCRs.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20167">https://doi.org/10.15479/AT-ISTA-20167</a>.
  ieee: H. Schön, “The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs,” Institute of Science and Technology Austria, 2025.
  ista: Schön H. 2025. The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding
    GPCRs. Institute of Science and Technology Austria.
  mla: Schön, Hanna. <i>The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs Encoding
    GPCRs</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20167">10.15479/AT-ISTA-20167</a>.
  short: H. Schön, The ER Complex SUTU-7/MACO-1 Regulates the Fate of MRNAs Encoding
    GPCRs, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-13T11:13:13Z
date_published: 2025-08-13T00:00:00Z
date_updated: 2026-08-13T13:05:37Z
day: '13'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaDe
doi: 10.15479/AT-ISTA-20167
doi_confirm: '1'
file:
- access_level: closed
  checksum: b40c74404b8d9593802dabf57bfdf10f
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: hschoen
  date_created: 2025-09-08T14:33:50Z
  date_updated: 2025-09-09T08:57:04Z
  file_id: '20311'
  file_name: 2025_Schoen_Hanna_Thesis.docx
  file_size: 78812587
  relation: source_file
- access_level: closed
  checksum: 16abc3ff66396ce2457fe07ffa8bed90
  content_type: application/pdf
  creator: hschoen
  date_created: 2025-09-11T14:20:59Z
  date_updated: 2026-08-13T13:05:36Z
  embargo: 2027-03-15
  embargo_to: open_access
  file_id: '20347'
  file_name: 2025_Schoen_Hanna_Thesis.pdf
  file_size: 9667057
  relation: main_file
file_date_updated: 2026-08-13T13:05:36Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa_version: Published Version
page: '171'
project:
- _id: 23870BE8-32DE-11EA-91FC-C7463DDC885E
  grant_number: 209504/A/17/Z
  name: Molecular mechanisms of neural circuit function
- _id: 23813290-32DE-11EA-91FC-C7463DDC885E
  grant_number: ALTF 302-2019
  name: Control of gene expression at the endoplasmic reticulum
publication_identifier:
  isbn:
  - 978-3-99078-061-9
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
title: The ER complex SUTU-7/MACO-1 regulates the fate of mRNAs encoding GPCRs
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20538'
abstract:
- lang: eng
  text: In this study, we describe an integrated approach for methyl group assignment
    comprising precursor-based selective methyl group labeling, a novel pulse sequence
    for methyl to backbone coherence transfer and chemical shift predictions using
    UCBShift 2.0. The utility of this novel α-ketoacid isotopologue is shown by the
    adaptation of an HMBC-HMQC pulse sequence that simultaneously connects geminal
    methyl groups of leucine and valine residues to each other and to the protein
    backbone. By additional 13C,2H-labeling of residues other than valine and leucine
    residues of the protein, important chemical shift information about neighboring
    residues (following valine and leucine residues) can be achieved. Thus, different
    valine and leucine residues in a protein can be characterized as a specific chemical
    shift vector. Frequency matching with predicted chemical shifts via UCBShift 2.0
    using experimental data taken from a subset of the BMRB database revealed a correct
    assignment performance of about 90%. With applications to proteins of 60.2 kDa
    and 134 kDa (4 × 33.5 kDa) in size, we demonstrate that the approach provides
    valuable information even for very large proteins.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: A.L.P and G.T were funded by the “New Ideas” program by Vienna Doctoral
  School in Chemistry. S.K. was funded by the Austrian Science Fund FWF P35098-B.
  This work was supported financially by the Austrian Science Fund (FWF, grant numbers
  I06223 and I5812-B, “AlloSpace”). This research was supported by the Scientific
  Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through
  resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support
  Facility (LSF). We thank Celina Sailer for assistance with the analysis of the NMR
  spectrum of HsTom70.
article_number: '169465'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Sonja
  full_name: Knödlstorfer, Sonja
  last_name: Knödlstorfer
- first_name: Giorgia
  full_name: Toscano, Giorgia
  id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
  last_name: Toscano
- first_name: Aleksandra L.
  full_name: Ptaszek, Aleksandra L.
  last_name: Ptaszek
- first_name: Georg
  full_name: Kontaxis, Georg
  last_name: Kontaxis
- first_name: Federico
  full_name: Napoli, Federico
  id: d42e08e7-f4fc-11eb-af0a-d71e26138f1b
  last_name: Napoli
  orcid: 0000-0002-9043-136X
- first_name: Jakob
  full_name: Schneider, Jakob
  id: 64368429-eb97-11eb-a6c2-c980b1f44415
  last_name: Schneider
- first_name: Katharina
  full_name: Maier, Katharina
  last_name: Maier
- first_name: Anna
  full_name: Kapitonova, Anna
  id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
  last_name: Kapitonova
- first_name: Roman J.
  full_name: Lichtenecker, Roman J.
  last_name: Lichtenecker
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Robert
  full_name: Konrat, Robert
  last_name: Konrat
citation:
  ama: Knödlstorfer S, Toscano G, Ptaszek AL, et al. A novel HMBC-CC-HMQC NMR strategy
    for methyl assignment using triple-13C-labeled α-ketoisovalerate integrated with
    UCBShift 2.0. <i>Journal of Molecular Biology</i>. 2025;437(23). doi:<a href="https://doi.org/10.1016/j.jmb.2025.169465">10.1016/j.jmb.2025.169465</a>
  apa: Knödlstorfer, S., Toscano, G., Ptaszek, A. L., Kontaxis, G., Napoli, F., Schneider,
    J., … Konrat, R. (2025). A novel HMBC-CC-HMQC NMR strategy for methyl assignment
    using triple-13C-labeled α-ketoisovalerate integrated with UCBShift 2.0. <i>Journal
    of Molecular Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.jmb.2025.169465">https://doi.org/10.1016/j.jmb.2025.169465</a>
  chicago: Knödlstorfer, Sonja, Giorgia Toscano, Aleksandra L. Ptaszek, Georg Kontaxis,
    Federico Napoli, Jakob Schneider, Katharina Maier, et al. “A Novel HMBC-CC-HMQC
    NMR Strategy for Methyl Assignment Using Triple-13C-Labeled α-Ketoisovalerate
    Integrated with UCBShift 2.0.” <i>Journal of Molecular Biology</i>. Elsevier,
    2025. <a href="https://doi.org/10.1016/j.jmb.2025.169465">https://doi.org/10.1016/j.jmb.2025.169465</a>.
  ieee: S. Knödlstorfer <i>et al.</i>, “A novel HMBC-CC-HMQC NMR strategy for methyl
    assignment using triple-13C-labeled α-ketoisovalerate integrated with UCBShift
    2.0,” <i>Journal of Molecular Biology</i>, vol. 437, no. 23. Elsevier, 2025.
  ista: Knödlstorfer S, Toscano G, Ptaszek AL, Kontaxis G, Napoli F, Schneider J,
    Maier K, Kapitonova A, Lichtenecker RJ, Schanda P, Konrat R. 2025. A novel HMBC-CC-HMQC
    NMR strategy for methyl assignment using triple-13C-labeled α-ketoisovalerate
    integrated with UCBShift 2.0. Journal of Molecular Biology. 437(23), 169465.
  mla: Knödlstorfer, Sonja, et al. “A Novel HMBC-CC-HMQC NMR Strategy for Methyl Assignment
    Using Triple-13C-Labeled α-Ketoisovalerate Integrated with UCBShift 2.0.” <i>Journal
    of Molecular Biology</i>, vol. 437, no. 23, 169465, Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.jmb.2025.169465">10.1016/j.jmb.2025.169465</a>.
  short: S. Knödlstorfer, G. Toscano, A.L. Ptaszek, G. Kontaxis, F. Napoli, J. Schneider,
    K. Maier, A. Kapitonova, R.J. Lichtenecker, P. Schanda, R. Konrat, Journal of
    Molecular Biology 437 (2025).
date_created: 2025-10-26T23:01:35Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-08-13T14:19:02Z
day: '01'
ddc:
- '540'
department:
- _id: PaSc
- _id: GradSch
doi: 10.1016/j.jmb.2025.169465
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publication: Journal of Molecular Biology
publication_identifier:
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  issn:
  - 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
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title: A novel HMBC-CC-HMQC NMR strategy for methyl assignment using triple-13C-labeled
  α-ketoisovalerate integrated with UCBShift 2.0
tmp:
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type: journal_article
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abstract:
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  text: The specific introduction of ^1H-^13C or ^1H-^15N moieties into otherwise
    deuterated proteins holds great potential for high-resolution solution and magic-angle
    spinning (MAS) NMR studies of protein structure and dynamics. Arginine residues
    play key roles for example at active sites of enzymes. Taking advantage of a chemically
    synthesized Arg with a ^13C-^1H2 group in an otherwise deuterated backbone, we
    demonstrate here the usefulness of proton-detected MAS NMR approaches to probe
    arginine dynamics. In experiments with crystalline ubiquitin and the 134 kDa tetrameric
    enzyme malate dehydrogenase we detected a wide range of motions, from sites that
    are rigid on time scales of at least tens of milliseconds to residues undergoing
    predominantly nanosecond motions. Spin-relaxation and dipolar-coupling measurements
    enabled quantitative determination of these dynamics. We observed microsecond
    dynamics of residue Arg54 in crystalline ubiquitin, whose backbone is known to
    sample different β-turn conformations on this time scale. The labeling scheme
    and experiments presented here expand the toolkit for high-resolution proton-detected
    MAS NMR.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: This work was supported financially by the Austrian Science Fund
  (FWF, Grant No. I5812-B, “AlloSpace”). This research was supported by the Scientific
  Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through
  resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support
  Facility (LSF). We thank Petra Rovò and Margarita Valhondo Falcón for excellent
  support of the NMR facility.
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article_processing_charge: Yes (via OA deal)
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author:
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  full_name: Rohden, Darja
  id: 81dc668a-19fa-11f0-bf31-d56534059ef3
  last_name: Rohden
- first_name: Federico
  full_name: Napoli, Federico
  id: d42e08e7-f4fc-11eb-af0a-d71e26138f1b
  last_name: Napoli
  orcid: 0000-0002-9043-136X
- first_name: Anna
  full_name: Kapitonova, Anna
  id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
  last_name: Kapitonova
- first_name: Benjamin
  full_name: Tatman, Benjamin
  id: 71cda2f3-e604-11ee-a1df-da10587eda3f
  last_name: Tatman
- first_name: Roman J.
  full_name: Lichtenecker, Roman J.
  last_name: Lichtenecker
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: Rohden D, Napoli F, Kapitonova A, Tatman B, Lichtenecker RJ, Schanda P. Arginine
    dynamics probed by magic-angle spinning NMR with a specific isotope-labeling scheme.
    <i>Journal of Molecular Biology</i>. 2025;437(23). doi:<a href="https://doi.org/10.1016/j.jmb.2025.169379">10.1016/j.jmb.2025.169379</a>
  apa: Rohden, D., Napoli, F., Kapitonova, A., Tatman, B., Lichtenecker, R. J., &#38;
    Schanda, P. (2025). Arginine dynamics probed by magic-angle spinning NMR with
    a specific isotope-labeling scheme. <i>Journal of Molecular Biology</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.jmb.2025.169379">https://doi.org/10.1016/j.jmb.2025.169379</a>
  chicago: Rohden, Darja, Federico Napoli, Anna Kapitonova, Benjamin Tatman, Roman
    J. Lichtenecker, and Paul Schanda. “Arginine Dynamics Probed by Magic-Angle Spinning
    NMR with a Specific Isotope-Labeling Scheme.” <i>Journal of Molecular Biology</i>.
    Elsevier, 2025. <a href="https://doi.org/10.1016/j.jmb.2025.169379">https://doi.org/10.1016/j.jmb.2025.169379</a>.
  ieee: D. Rohden, F. Napoli, A. Kapitonova, B. Tatman, R. J. Lichtenecker, and P.
    Schanda, “Arginine dynamics probed by magic-angle spinning NMR with a specific
    isotope-labeling scheme,” <i>Journal of Molecular Biology</i>, vol. 437, no. 23.
    Elsevier, 2025.
  ista: Rohden D, Napoli F, Kapitonova A, Tatman B, Lichtenecker RJ, Schanda P. 2025.
    Arginine dynamics probed by magic-angle spinning NMR with a specific isotope-labeling
    scheme. Journal of Molecular Biology. 437(23), 169379.
  mla: Rohden, Darja, et al. “Arginine Dynamics Probed by Magic-Angle Spinning NMR
    with a Specific Isotope-Labeling Scheme.” <i>Journal of Molecular Biology</i>,
    vol. 437, no. 23, 169379, Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.jmb.2025.169379">10.1016/j.jmb.2025.169379</a>.
  short: D. Rohden, F. Napoli, A. Kapitonova, B. Tatman, R.J. Lichtenecker, P. Schanda,
    Journal of Molecular Biology 437 (2025).
corr_author: '1'
date_created: 2025-08-31T22:01:33Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-08-13T14:19:01Z
day: '01'
ddc:
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department:
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doi: 10.1016/j.jmb.2025.169379
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publication: Journal of Molecular Biology
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quality_controlled: '1'
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title: Arginine dynamics probed by magic-angle spinning NMR with a specific isotope-labeling
  scheme
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 437
year: '2025'
...
---
_id: '19956'
abstract:
- lang: eng
  text: The specific introduction of 1H-13C or 1H-15N moieties into otherwise deuterated
    proteins holds great potential for high-resolution solution and magic-angle spinning
    (MAS) NMR studies of protein structure and dynamics. Arginine residues play key
    roles for example at active sites of enzymes. Taking advantage of a chemically
    synthesized Arg with a 13C-1H2 group in an otherwise deuterated backbone, we demonstrate
    here the usefulness of proton-detected arginine MAS NMR approaches to probe arginine
    dynamics. In experiments on crystalline ubiquitin and the 134 kDa tetrameric enzyme
    malate dehydrogenase we detected a wide range of motions, from sites that are
    rigid on time scales of at least tens of milliseconds to residues undergoing predominantly
    nanosecond motions. Spin-relaxation and dipolar-coupling measurements enabled
    quantitative determination of these dynamics. We observed microsecond dynamics
    of residue Arg54 in crystalline ubiquitin, whose backbone is known to sample different
    β-turn conformations on this time scale. The labeling scheme and experiments presented
    here expand the toolkit for high-resolution proton-detected MAS NMR
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
article_processing_charge: No
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: Schanda P. Arginine Dynamics Probed by Magic-Angle Spinning NMR with a Specific
    Isotope-Labeling Scheme. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19956">10.15479/AT-ISTA-19956</a>
  apa: Schanda, P. (2025). Arginine Dynamics Probed by Magic-Angle Spinning NMR with
    a Specific Isotope-Labeling Scheme. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-19956">https://doi.org/10.15479/AT-ISTA-19956</a>
  chicago: Schanda, Paul. “Arginine Dynamics Probed by Magic-Angle Spinning NMR with
    a Specific Isotope-Labeling Scheme.” Institute of Science and Technology Austria,
    2025. <a href="https://doi.org/10.15479/AT-ISTA-19956">https://doi.org/10.15479/AT-ISTA-19956</a>.
  ieee: P. Schanda, “Arginine Dynamics Probed by Magic-Angle Spinning NMR with a Specific
    Isotope-Labeling Scheme.” Institute of Science and Technology Austria, 2025.
  ista: Schanda P. 2025. Arginine Dynamics Probed by Magic-Angle Spinning NMR with
    a Specific Isotope-Labeling Scheme, Institute of Science and Technology Austria,
    <a href="https://doi.org/10.15479/AT-ISTA-19956">10.15479/AT-ISTA-19956</a>.
  mla: Schanda, Paul. <i>Arginine Dynamics Probed by Magic-Angle Spinning NMR with
    a Specific Isotope-Labeling Scheme</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19956">10.15479/AT-ISTA-19956</a>.
  short: P. Schanda, (2025).
contributor:
- contributor_type: researcher
  first_name: Darja
  last_name: Rohden
- contributor_type: researcher
  first_name: Federico
  last_name: Napoli
- contributor_type: researcher
  first_name: Ben
  last_name: Tatman
- contributor_type: researcher
  first_name: Paul
  last_name: Schanda
corr_author: '1'
date_created: 2025-07-03T04:21:37Z
date_published: 2025-07-03T00:00:00Z
date_updated: 2026-08-13T14:19:01Z
day: '03'
ddc:
- '572'
department:
- _id: PaSc
doi: 10.15479/AT-ISTA-19956
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  grant_number: I05812
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publisher: Institute of Science and Technology Austria
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title: Arginine Dynamics Probed by Magic-Angle Spinning NMR with a Specific Isotope-Labeling
  Scheme
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abstract:
- lang: eng
  text: "Plant growth and development rely significantly on phytohormones, with auxin
    serving as a master regulator, orchestrating processes from embryogenesis to organogenesis,
    vascular patterning, and environmental adaptation. Since its conceptual proposition
    by Charles Darwin in 1880 as an endogenous chemical signal influencing phototropism
    in grass, auxin has captivated scientists seeking to understand how such a small
    molecule exerts a profound influence on plant development.\r\nOne particularly
    fascinating aspect of auxin function is its ability to self-organize its transport.
    Through a feedback mechanism between auxin perception and directional transport—primarily
    mediated by PIN auxin transporters—auxin establishes narrow transport channels.
    This phenomenon, known as auxin canalization, is fundamental to vascular formation,
    regeneration, and other key developmental processes. Despite advances in our understanding,
    driven by experimental studies and computational models, auxin canalization remains
    an enigma, with many unanswered questions.\r\nLike other hormones, auxin functions
    through intricate signaling pathways. It operates through at least two distinct
    signaling mechanisms: the well-characterized canonical pathway and the less understood
    non-canonical pathway. While significant progress has been made in elucidating
    the canonical pathway, the non-canonical mechanisms remain less defined and require
    further investigation.\r\nIn this study, we revisit the non-canonical auxin signaling
    pathway mediated by the cell-surface complex Auxin Binding Protein 1-Transmembrane
    Kinase 1 (ABP1-TMK1), with a particular focus on its downstream phosphorylation
    events. We reveal that this auxin-mediated phosphorylation is conserved across
    the green lineage, underscoring its fundamental role in plant development. We
    explore key phosphorylation targets, particularly PIN2, which is essential for
    root gravitropism. To further understand TMK1’s role in diverse developmental
    processes, we identified and investigated its interactors as potential co-receptors
    or regulatory components within its signaling network.\r\nGiven the previously
    established role of ABP1-TMK1 in auxin canalization, we sought to further investigate
    this process and identified several TMK1 interactors also involved in this intricate
    mechanism.\r\nThese findings provide new insights into the complex regulation
    of auxin canalization, highlighting a broader and more interconnected signaling
    framework than previously understood."
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: I would like to acknowledge the facilities at ISTA, particularly
  LSF, IOF, and, of course, the plant facility, for providing the necessary resources
  for my research.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
citation:
  ama: 'Monzer A. Cell-surface auxin signaling: Linking molecular pathways to plant
    development. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19395">10.15479/AT-ISTA-19395</a>'
  apa: 'Monzer, A. (2025). <i>Cell-surface auxin signaling: Linking molecular pathways
    to plant development</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-19395">https://doi.org/10.15479/AT-ISTA-19395</a>'
  chicago: 'Monzer, Aline. “Cell-Surface Auxin Signaling: Linking Molecular Pathways
    to Plant Development.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19395">https://doi.org/10.15479/AT-ISTA-19395</a>.'
  ieee: 'A. Monzer, “Cell-surface auxin signaling: Linking molecular pathways to plant
    development,” Institute of Science and Technology Austria, 2025.'
  ista: 'Monzer A. 2025. Cell-surface auxin signaling: Linking molecular pathways
    to plant development. Institute of Science and Technology Austria.'
  mla: 'Monzer, Aline. <i>Cell-Surface Auxin Signaling: Linking Molecular Pathways
    to Plant Development</i>. Institute of Science and Technology Austria, 2025, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-19395">10.15479/AT-ISTA-19395</a>.'
  short: 'A. Monzer, Cell-Surface Auxin Signaling: Linking Molecular Pathways to Plant
    Development, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-03-12T14:25:42Z
date_published: 2025-03-13T00:00:00Z
date_updated: 2026-08-14T09:33:46Z
day: '13'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JiFr
doi: 10.15479/AT-ISTA-19395
doi_confirm: '1'
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language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '160'
publication_identifier:
  eisbn:
  - 978-3-99078-054-1
  eissn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '12291'
    relation: part_of_dissertation
    status: public
  - id: '14826'
    relation: part_of_dissertation
    status: public
  - id: '19399'
    relation: part_of_dissertation
    status: public
  - id: '19398'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
title: 'Cell-surface auxin signaling: Linking molecular pathways to plant development'
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19399'
abstract:
- lang: eng
  text: Phytohormone auxin and its directional transport mediate much of the remarkably
    plastic development of higher plants. Positive feedback between auxin signaling
    and transport is a key prerequisite for (i) self-organizing processes including
    vascular tissue formation and (ii) directional growth responses such as gravitropism.
    Here we identify a mechanism, by which auxin signaling directly targets PIN auxin
    transporters. Via the cell-surface ABP1-TMK1 receptor module, auxin rapidly induces
    phosphorylation and thus stabilization of PIN2. Following gravistimulation, initial
    auxin asymmetry activates autophosphorylation of the TMK1 kinase. This induces
    TMK1 interaction with and phosphorylation of PIN2, stabilizing PIN2 at the lower
    root side, thus reinforcing asymmetric auxin flow for root bending. Upstream of
    TMK1 in this regulation, ABP1 acts redundantly with the root-expressed ABP1-LIKE
    auxin receptor ABL3. Such positive feedback between cell-surface auxin signaling
    and PIN-mediated polar auxin transport is fundamental for robust root gravitropism
    and presumably also for other self-organizing developmental phenomena.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: 'We thank W. Gray for providing material; N. Gnyliukh and E. Cervenova
  for help with manuscript preparation; J. Schmid for help with cloning. We thank
  Dolf Weijers, Mark Roosjen, and Andre Kuhn for discussions and support with phospho-proteomic
  analyses. We thank the Bioimaging and Life Science facilities at ISTA for their
  excellent service and assistance. The research leading to these results has received
  funding from the European Research Council (ERC) under the European Union’s Horizon
  2020 research and innovation program grant agreement No 742985 and Austrian Science
  Fund (FWF): I3630-775 B25 to J.F; National Natural Science Foundation of China (Grant
  32130010, 31422008), start-up funds from FAFU to T.X., Y.J. was funded by ERC no.
  3363360-APPL under FP/2007-2013. L.R. was supported by FP7-PEOPLE-2011-COFUND ISTFELLOW
  program (IC1023FELL01) and the European Molecular Biology Organization (EMBO) long-term
  postdoctoral fellowship (ALTF 985- 2016). S.T. was supported by the National Natural
  Science Foundation of China (32321001).'
article_processing_charge: No
author:
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Lukas
  full_name: Fiedler, Lukas
  id: 7c417475-8972-11ed-ae7b-8b674ca26986
  last_name: Fiedler
- first_name: Minxia
  full_name: Zou, Minxia
  id: 5c243f41-03f3-11ec-841c-96faf48a7ef9
  last_name: Zou
- first_name: Caterina
  full_name: Giannini, Caterina
  id: e3fdddd5-f6e0-11ea-865d-ca99ee6367f4
  last_name: Giannini
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
- first_name: Dmitrii
  full_name: Vladimirtsev, Dmitrii
  id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
  last_name: Vladimirtsev
- first_name: Marek
  full_name: Randuch, Marek
  id: 6ac4636d-15b2-11ec-abd3-fb8df79972ae
  last_name: Randuch
- first_name: Yongfan
  full_name: Yu, Yongfan
  last_name: Yu
- first_name: Zuzana
  full_name: Gelová, Zuzana
  id: 0AE74790-0E0B-11E9-ABC7-1ACFE5697425
  last_name: Gelová
  orcid: 0000-0003-4783-1752
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
- first_name: Jakub
  full_name: Hajny, Jakub
  id: 4800CC20-F248-11E8-B48F-1D18A9856A87
  last_name: Hajny
  orcid: 0000-0003-2140-7195
- first_name: Meng
  full_name: Chen, Meng
  last_name: Chen
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Lukas
  full_name: Hörmayer, Lukas
  id: 2EEE7A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Hörmayer
  orcid: 0000-0001-8295-2926
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Maria Mar
  full_name: Marques-Bueno, Maria Mar
  last_name: Marques-Bueno
- first_name: Zainab
  full_name: Quddoos, Zainab
  id: 32ff3c64-04a0-11f0-a50f-d0c45bfac466
  last_name: Quddoos
- first_name: Gergely
  full_name: Molnar, Gergely
  id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
  last_name: Molnar
- first_name: Tongda
  full_name: Xu, Tongda
  last_name: Xu
- first_name: Ivan
  full_name: Kulich, Ivan
  id: 57a1567c-8314-11eb-9063-c9ddc3451a54
  last_name: Kulich
- first_name: Yvon
  full_name: Jaillais, Yvon
  last_name: Jaillais
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Rodriguez Solovey L, Fiedler L, Zou M, et al. ABP1/ABL3-TMK1 cell-surface auxin
    signaling directly targets PIN2-mediated auxin fluxes for root gravitropism. <i>bioRxiv</i>.
    doi:<a href="https://doi.org/10.1101/2022.11.30.518503">10.1101/2022.11.30.518503</a>
  apa: Rodriguez Solovey, L., Fiedler, L., Zou, M., Giannini, C., Monzer, A., Vladimirtsev,
    D., … Friml, J. (n.d.). ABP1/ABL3-TMK1 cell-surface auxin signaling directly targets
    PIN2-mediated auxin fluxes for root gravitropism. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2022.11.30.518503">https://doi.org/10.1101/2022.11.30.518503</a>
  chicago: Rodriguez Solovey, Lesia, Lukas Fiedler, Minxia Zou, Caterina Giannini,
    Aline Monzer, Dmitrii Vladimirtsev, Marek Randuch, et al. “ABP1/ABL3-TMK1 Cell-Surface
    Auxin Signaling Directly Targets PIN2-Mediated Auxin Fluxes for Root Gravitropism.”
    <i>BioRxiv</i>, n.d. <a href="https://doi.org/10.1101/2022.11.30.518503">https://doi.org/10.1101/2022.11.30.518503</a>.
  ieee: L. Rodriguez Solovey <i>et al.</i>, “ABP1/ABL3-TMK1 cell-surface auxin signaling
    directly targets PIN2-mediated auxin fluxes for root gravitropism,” <i>bioRxiv</i>.
    .
  ista: Rodriguez Solovey L, Fiedler L, Zou M, Giannini C, Monzer A, Vladimirtsev
    D, Randuch M, Yu Y, Gelová Z, Verstraeten I, Hajny J, Chen M, Tan S, Hörmayer
    L, Li L, Marques-Bueno MM, Quddoos Z, Molnar G, Xu T, Kulich I, Jaillais Y, Friml
    J. ABP1/ABL3-TMK1 cell-surface auxin signaling directly targets PIN2-mediated
    auxin fluxes for root gravitropism. bioRxiv, <a href="https://doi.org/10.1101/2022.11.30.518503">10.1101/2022.11.30.518503</a>.
  mla: Rodriguez Solovey, Lesia, et al. “ABP1/ABL3-TMK1 Cell-Surface Auxin Signaling
    Directly Targets PIN2-Mediated Auxin Fluxes for Root Gravitropism.” <i>BioRxiv</i>,
    doi:<a href="https://doi.org/10.1101/2022.11.30.518503">10.1101/2022.11.30.518503</a>.
  short: L. Rodriguez Solovey, L. Fiedler, M. Zou, C. Giannini, A. Monzer, D. Vladimirtsev,
    M. Randuch, Y. Yu, Z. Gelová, I. Verstraeten, J. Hajny, M. Chen, S. Tan, L. Hörmayer,
    L. Li, M.M. Marques-Bueno, Z. Quddoos, G. Molnar, T. Xu, I. Kulich, Y. Jaillais,
    J. Friml, BioRxiv (n.d.).
corr_author: '1'
das_tickbox: '1'
date_created: 2025-03-13T08:36:48Z
date_published: 2025-02-20T00:00:00Z
date_updated: 2026-08-14T09:33:45Z
day: '20'
ddc:
- '580'
department:
- _id: JiFr
- _id: XiFe
doi: 10.1101/2022.11.30.518503
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2022.11.30.518503
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 26060676-B435-11E9-9278-68D0E5697425
  grant_number: ALTF 985-2016
  name: Cell surface receptor complexes for auxin signaling in plants
publication: bioRxiv
publication_status: draft
related_material:
  record:
  - id: '20656'
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    status: public
  - id: '20364'
    relation: dissertation_contains
    status: public
  - id: '19395'
    relation: dissertation_contains
    status: public
status: public
title: ABP1/ABL3-TMK1 cell-surface auxin signaling directly targets PIN2-mediated
  auxin fluxes for root gravitropism
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19398'
abstract:
- lang: eng
  text: Receptor-like kinases (RLKs), particularly the Transmembrane Kinase (TMK)
    family, play essential roles in signaling and development, with TMKs being key
    components of auxin perception and downstream phosphorylation events. While TMKs’
    involvement in auxin canalization, a process essential for vasculature formation
    and regeneration, has been established, nonetheless, the additional signaling
    and regulatory partners remain poorly understood. In this study, we identify and
    characterize seven leucine-rich repeat RLKs (TINT1–TINT7) as novel interactors
    of TMK1, revealing their diverse evolutionary, structural, and functional characteristics.
    Our results show that TINTs interact with TMK1 and highlight their roles in regulating
    various developmental processes. Majority of TINTs contributes, together with
    TMK1, to auxin canalization, with TINT5 linking TMK1 to other canalization component
    CAMEL. Beyond canalization, we also establish the role of TINT-TMK1 interactions
    in processes such as stomatal movement and the hypocotyl’s gravitropic response.
    These findings suggest that TINTs, through their interaction with TMK1, are integral
    components of various signaling networks, contributing to both auxin canalization
    and broader plant development.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: We deeply appreciate M. Wrzaczek’s constructive input and insightful
  discussions, which significantly enriched this work. We thank L. Fiedler for helping
  with the heat map and for the discussions. We also thank the facilities at ISTA,
  the imaging and optics (IOF) and Lab Support (LSF) facilities for their service
  and assistance.
article_processing_charge: No
author:
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
- first_name: Ewa
  full_name: Mazur, Ewa
  last_name: Mazur
- first_name: Lesia
  full_name: Rodriguez Solovey, Lesia
  id: 3922B506-F248-11E8-B48F-1D18A9856A87
  last_name: Rodriguez Solovey
  orcid: 0000-0002-7244-7237
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Minxia
  full_name: Zou, Minxia
  id: 5c243f41-03f3-11ec-841c-96faf48a7ef9
  last_name: Zou
- first_name: Michael
  full_name: Smejkal, Michael
  id: 79a5a1be-04a3-11f0-ba18-a1730e0b58e9
  last_name: Smejkal
- first_name: Ema
  full_name: Cervenova, Ema
  id: 9f185b95-04a3-11f0-8245-f5e32eeb470f
  last_name: Cervenova
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Monzer A, Mazur E, Rodriguez Solovey L, et al. TMK interacting network of receptor
    like kinases for auxin canalization and beyond. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>
  apa: Monzer, A., Mazur, E., Rodriguez Solovey, L., Gallei, M. C., Zou, M., Smejkal,
    M., … Friml, J. (n.d.). TMK interacting network of receptor like kinases for auxin
    canalization and beyond. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2025.02.28.640727">https://doi.org/10.1101/2025.02.28.640727</a>
  chicago: Monzer, Aline, Ewa Mazur, Lesia Rodriguez Solovey, Michelle C Gallei, Minxia
    Zou, Michael Smejkal, Ema Cervenova, and Jiří Friml. “TMK Interacting Network
    of Receptor like Kinases for Auxin Canalization and Beyond.” <i>BioRxiv</i>, n.d.
    <a href="https://doi.org/10.1101/2025.02.28.640727">https://doi.org/10.1101/2025.02.28.640727</a>.
  ieee: A. Monzer <i>et al.</i>, “TMK interacting network of receptor like kinases
    for auxin canalization and beyond,” <i>bioRxiv</i>. .
  ista: Monzer A, Mazur E, Rodriguez Solovey L, Gallei MC, Zou M, Smejkal M, Cervenova
    E, Friml J. TMK interacting network of receptor like kinases for auxin canalization
    and beyond. bioRxiv, <a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>.
  mla: Monzer, Aline, et al. “TMK Interacting Network of Receptor like Kinases for
    Auxin Canalization and Beyond.” <i>BioRxiv</i>, doi:<a href="https://doi.org/10.1101/2025.02.28.640727">10.1101/2025.02.28.640727</a>.
  short: A. Monzer, E. Mazur, L. Rodriguez Solovey, M.C. Gallei, M. Zou, M. Smejkal,
    E. Cervenova, J. Friml, BioRxiv (n.d.).
corr_author: '1'
das_tickbox: '1'
date_created: 2025-03-12T14:28:53Z
date_published: 2025-03-02T00:00:00Z
date_updated: 2026-08-14T09:33:45Z
day: '02'
ddc:
- '580'
department:
- _id: GradSch
- _id: JiFr
- _id: EvBe
doi: 10.1101/2025.02.28.640727
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.02.28.640727
month: '03'
oa: 1
oa_version: Published Version
publication: bioRxiv
publication_status: draft
related_material:
  record:
  - id: '19395'
    relation: dissertation_contains
    status: public
status: public
title: TMK interacting network of receptor like kinases for auxin canalization and
  beyond
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '21280'
abstract:
- lang: eng
  text: We give an algorithm that, with high probability, maintains a (1-ε)-approximate
    s-t maximum flow in undirected, uncapacitated n-vertex graphs undergoing m edge
    insertions in Õ(m+ n F^*/ε) total update time, where F^{*} is the maximum flow
    on the final graph. This is the first algorithm to achieve polylogarithmic amortized
    update time for dense graphs (m = Ω(n²)), and more generally, for graphs where
    F^* = Õ(m/n). At the heart of our incremental algorithm is the residual graph
    sparsification technique of Karger and Levine [SICOMP '15], originally designed
    for computing exact maximum flows in the static setting. Our main contributions
    are (i) showing how to maintain such sparsifiers for approximate maximum flows
    in the incremental setting and (ii) generalizing the cut sparsification framework
    of Fung et al. [SICOMP '19] from undirected graphs to balanced directed graphs.
acknowledgement: "Monika Henzinger and A. R. Sricharan: This project has received
  funding from the European Research Council (ERC) under the European Union’s Horizon
  2020 research and innovation\r\nprogramme (MoDynStruct, No. 101019564) and the Austrian
  Science Fund (FWF) grant DOI\r\n10.55776/Z422, grant DOI 10.55776/I5982, and grant
  DOI 10.55776/P33775 with additional funding from the netidee SCIENCE Stiftung, 2020–2024.
  Harald Räcke: This project has received funding from the Deutsche Forschungsgemeinschaft
  (DFG, German Research Foundation) – 498605858 and 470029389."
alternative_title:
- LIPIcs
article_processing_charge: No
arxiv: 1
author:
- first_name: Gramoz
  full_name: Goranci, Gramoz
  last_name: Goranci
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Harald
  full_name: Räcke, Harald
  last_name: Räcke
- first_name: A.
  full_name: Sricharan, A.
  last_name: Sricharan
citation:
  ama: 'Goranci G, Henzinger M, Räcke H, Sricharan A. Incremental approximate maximum
    flow via residual graph sparsification. In: <i>52nd International Colloquium on
    Automata, Languages, and Programming</i>. Vol 334. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik; 2025:91:1-91:20. doi:<a href="https://doi.org/10.4230/lipics.icalp.2025.91">10.4230/lipics.icalp.2025.91</a>'
  apa: 'Goranci, G., Henzinger, M., Räcke, H., &#38; Sricharan, A. (2025). Incremental
    approximate maximum flow via residual graph sparsification. In <i>52nd International
    Colloquium on Automata, Languages, and Programming</i> (Vol. 334, p. 91:1-91:20).
    Aarhus, Denmark: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/lipics.icalp.2025.91">https://doi.org/10.4230/lipics.icalp.2025.91</a>'
  chicago: Goranci, Gramoz, Monika Henzinger, Harald Räcke, and A. Sricharan. “Incremental
    Approximate Maximum Flow via Residual Graph Sparsification.” In <i>52nd International
    Colloquium on Automata, Languages, and Programming</i>, 334:91:1-91:20. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2025. <a href="https://doi.org/10.4230/lipics.icalp.2025.91">https://doi.org/10.4230/lipics.icalp.2025.91</a>.
  ieee: G. Goranci, M. Henzinger, H. Räcke, and A. Sricharan, “Incremental approximate
    maximum flow via residual graph sparsification,” in <i>52nd International Colloquium
    on Automata, Languages, and Programming</i>, Aarhus, Denmark, 2025, vol. 334,
    p. 91:1-91:20.
  ista: 'Goranci G, Henzinger M, Räcke H, Sricharan A. 2025. Incremental approximate
    maximum flow via residual graph sparsification. 52nd International Colloquium
    on Automata, Languages, and Programming. ICALP: Automata, Languages and Programming,
    LIPIcs, vol. 334, 91:1-91:20.'
  mla: Goranci, Gramoz, et al. “Incremental Approximate Maximum Flow via Residual
    Graph Sparsification.” <i>52nd International Colloquium on Automata, Languages,
    and Programming</i>, vol. 334, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2025, p. 91:1-91:20, doi:<a href="https://doi.org/10.4230/lipics.icalp.2025.91">10.4230/lipics.icalp.2025.91</a>.
  short: G. Goranci, M. Henzinger, H. Räcke, A. Sricharan, in:, 52nd International
    Colloquium on Automata, Languages, and Programming, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2025, p. 91:1-91:20.
conference:
  end_date: 2025-07-11
  location: Aarhus, Denmark
  name: 'ICALP: Automata, Languages and Programming'
  start_date: 2025-07-08
corr_author: '1'
date_created: 2026-02-17T08:26:06Z
date_published: 2025-06-30T00:00:00Z
date_updated: 2026-08-20T06:28:00Z
day: '30'
ddc:
- '000'
department:
- _id: MoHe
doi: 10.4230/lipics.icalp.2025.91
ec_funded: 1
external_id:
  arxiv:
  - '2502.09105'
file:
- access_level: open_access
  checksum: c178cf554e44204b9f64ebd9b54cf7ba
  content_type: application/pdf
  creator: dernst
  date_created: 2026-02-18T09:02:33Z
  date_updated: 2026-02-18T09:02:33Z
  file_id: '21315'
  file_name: 2025_ICALP_Goranci.pdf
  file_size: 944824
  relation: main_file
  success: 1
file_date_updated: 2026-02-18T09:02:33Z
has_accepted_license: '1'
intvolume: '       334'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 91:1-91:20
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
  grant_number: Z00422
  name: Efficient algorithms
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
  grant_number: I05982
  name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
  grant_number: P33775
  name: Fast Algorithms for a Reactive Network Layer
publication: 52nd International Colloquium on Automata, Languages, and Programming
publication_identifier:
  isbn:
  - '9783959773720'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
  record:
  - id: '22716'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Incremental approximate maximum flow via residual graph sparsification
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 334
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '21262'
abstract:
- lang: eng
  text: "Continuous Group Key Agreement (CGKA) is the primitive underlying secure
    group messaging. It allows a large group of N users to maintain a shared secret
    key that is frequently rotated by the\r\ngroup members in order to achieve forward
    secrecy and post compromise security. The group messaging scheme Messaging Layer
    Security (MLS) standardized by the IETF makes use of a CGKA called TreeKEM which
    arranges the N group members in a binary tree. Here, each node is associated with
    a public-key, each user is assigned one of the leaves, and a user knows the corresponding
    secret keys from their leaf to the root. To update the key material known to them,
    a user must just replace keys at log(N) nodes, which requires them to create and
    upload log(N) ciphertexts. Such updates must be processed sequentially by all
    users, which for large groups is impractical. To allow for concurrent updates,
    TreeKEM uses the “propose and commit” paradigm, where multiple users can concurrently
    propose to update (by just sampling a fresh leaf key), and a single user can then
    commit to all proposals at once. Unfortunately, this process destroys the binary
    tree structure as the tree gets pruned and some nodes must be “blanked” at the
    cost of increasing the in-degree of others, which makes the commit operation,
    as well as, future commits more costly. In the worst case, the update cost (in
    terms of uploaded ciphertexts) per user can grow from log(N) to Ω(N). In this
    work we provide two main contributions. First, we show that MLS’ communication
    complexity is bad not only in the worst case but also if the proposers and committers
    are chosen at random: even if there’s just one update proposal for every commit
    the expected cost is already over √N, and it approaches N as this ratio changes
    towards more proposals. Our second contribution is a new variant of propose and
    commit for\r\nTreeKEM which for moderate amounts of update proposals per commit
    provably achieves an update cost of Θ(log(N)) assuming the proposers and committers
    are chosen at random."
acknowledgement: B. Auerbach and B. Erol—Conducted part of this work at ISTA.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Benedikt
  full_name: Auerbach, Benedikt
  id: D33D2B18-E445-11E9-ABB7-15F4E5697425
  last_name: Auerbach
  orcid: 0000-0002-7553-6606
- first_name: Miguel
  full_name: Cueto Noval, Miguel
  id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc
  last_name: Cueto Noval
  orcid: 0000-0002-2505-4246
- first_name: Boran
  full_name: Erol, Boran
  last_name: Erol
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Auerbach B, Cueto Noval M, Erol B, Pietrzak KZ. Continuous group-key agreement:
    Concurrent updates without pruning. In: <i>45th Annual International Cryptology
    Conference</i>. Vol 16007. Springer Nature; 2025:141-172. doi:<a href="https://doi.org/10.1007/978-3-032-01913-4_5">10.1007/978-3-032-01913-4_5</a>'
  apa: 'Auerbach, B., Cueto Noval, M., Erol, B., &#38; Pietrzak, K. Z. (2025). Continuous
    group-key agreement: Concurrent updates without pruning. In <i>45th Annual International
    Cryptology Conference</i> (Vol. 16007, pp. 141–172). Santa Barbara, CA, United
    States: Springer Nature. <a href="https://doi.org/10.1007/978-3-032-01913-4_5">https://doi.org/10.1007/978-3-032-01913-4_5</a>'
  chicago: 'Auerbach, Benedikt, Miguel Cueto Noval, Boran Erol, and Krzysztof Z Pietrzak.
    “Continuous Group-Key Agreement: Concurrent Updates without Pruning.” In <i>45th
    Annual International Cryptology Conference</i>, 16007:141–72. Springer Nature,
    2025. <a href="https://doi.org/10.1007/978-3-032-01913-4_5">https://doi.org/10.1007/978-3-032-01913-4_5</a>.'
  ieee: 'B. Auerbach, M. Cueto Noval, B. Erol, and K. Z. Pietrzak, “Continuous group-key
    agreement: Concurrent updates without pruning,” in <i>45th Annual International
    Cryptology Conference</i>, Santa Barbara, CA, United States, 2025, vol. 16007,
    pp. 141–172.'
  ista: 'Auerbach B, Cueto Noval M, Erol B, Pietrzak KZ. 2025. Continuous group-key
    agreement: Concurrent updates without pruning. 45th Annual International Cryptology
    Conference. CRYPTO: International Cryptology Conference, LNCS, vol. 16007, 141–172.'
  mla: 'Auerbach, Benedikt, et al. “Continuous Group-Key Agreement: Concurrent Updates
    without Pruning.” <i>45th Annual International Cryptology Conference</i>, vol.
    16007, Springer Nature, 2025, pp. 141–72, doi:<a href="https://doi.org/10.1007/978-3-032-01913-4_5">10.1007/978-3-032-01913-4_5</a>.'
  short: B. Auerbach, M. Cueto Noval, B. Erol, K.Z. Pietrzak, in:, 45th Annual International
    Cryptology Conference, Springer Nature, 2025, pp. 141–172.
conference:
  end_date: 2025-08-21
  location: Santa Barbara, CA, United States
  name: 'CRYPTO: International Cryptology Conference'
  start_date: 2025-08-17
date_created: 2026-02-17T07:41:04Z
date_published: 2025-08-17T00:00:00Z
date_updated: 2026-08-21T10:53:16Z
day: '17'
department:
- _id: KrPi
doi: 10.1007/978-3-032-01913-4_5
intvolume: '     16007'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2025/1035
month: '08'
oa: 1
oa_version: Preprint
page: 141-172
publication: 45th Annual International Cryptology Conference
publication_identifier:
  eisbn:
  - '9783032019134'
  eissn:
  - 1611-3349
  isbn:
  - '9783032019127'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '22664'
    relation: dissertation_contains
    status: public
status: public
title: 'Continuous group-key agreement: Concurrent updates without pruning'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16007
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '19278'
abstract:
- lang: eng
  text: 'When two insulating, neutral materials are contacted and separated, they
    exchange electrical charge1. Experiments have long suggested that this ‘contact
    electrification’ is transitive, with different materials ordering into ‘triboelectric
    series’ based on the sign of charge acquired2. At the same time, the effect is
    plagued by unpredictability, preventing consensus on the mechanism and casting
    doubt on the rhyme and reason that series imply3. Here we expose an unanticipated
    connection between the unpredictability and order in contact electrification:
    nominally identical materials initially exchange charge randomly and intransitively,
    but—over repeated experiments—order into triboelectric series. We find that this
    evolution is driven by the act of contact itself—samples with more contacts in
    their history charge negatively to ones with fewer contacts. Capturing this ‘contact
    bias’ in a minimal model, we recreate both the initial randomness and ultimate
    order in numerical simulations and use it experimentally to force the appearance
    of a triboelectric series of our choosing. With a set of surface-sensitive techniques
    to search for the underlying alterations contact creates, we only find evidence
    of nanoscale morphological changes, pointing to a mechanism strongly coupled with
    mechanics. Our results highlight the centrality of contact history in contact
    electrification and suggest that focusing on the unpredictability that has long
    plagued the effect may hold the key to understanding it.'
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: EM-Fac
- _id: LifeSc
acknowledgement: This project has received financing from the European Research Council
  grant agreement no. 949120 under the European Union’s Horizon 2020 research and
  innovation programme. The Analytical Instrumentation Center of the TU Wien acknowledges
  support by the FFG project ‘ELSA’ under grant no. 884672. C.M.P. and M.O. acknowledge
  the state of Lower Austria and the European Regional Development Fund under grant
  no. WST3-F-542638/004-2021. This research was supported by the Scientific Service
  Units of the Institute of Science and Technology Austria through resources provided
  by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing facility,
  Electron Microscopy Facility and Lab Support Facility. We thank J. Garcia-Suarez
  and G. Anciaux for the suggestion to look into the roughness power spectral density.
  We thank I.-M. Strugaru for help with testing the device for Young’s modulus measurements.
  Open access funding provided by Institute of Science and Technology (IST Austria).
article_number: 664-669
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Juan Carlos A
  full_name: Sobarzo Ponce, Juan Carlos A
  id: 4B807D68-AE37-11E9-AC72-31CAE5697425
  last_name: Sobarzo Ponce
- first_name: Felix
  full_name: Pertl, Felix
  id: 6313aec0-15b2-11ec-abd3-ed67d16139af
  last_name: Pertl
  orcid: 0000-0003-0463-5794
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Tommaso
  full_name: Costanzo, Tommaso
  id: D93824F4-D9BA-11E9-BB12-F207E6697425
  last_name: Costanzo
  orcid: 0000-0001-9732-3815
- first_name: Markus
  full_name: Sauer, Markus
  last_name: Sauer
- first_name: Annette
  full_name: Foelske, Annette
  last_name: Foelske
- first_name: Markus
  full_name: Ostermann, Markus
  last_name: Ostermann
- first_name: Christian M.
  full_name: Pichler, Christian M.
  last_name: Pichler
- first_name: Yongkang
  full_name: Wang, Yongkang
  last_name: Wang
- first_name: Yuki
  full_name: Nagata, Yuki
  last_name: Nagata
- first_name: Mischa
  full_name: Bonn, Mischa
  last_name: Bonn
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
citation:
  ama: Sobarzo Ponce JCA, Pertl F, Balazs D, et al. Spontaneous ordering of identical
    materials into a triboelectric series. <i>Nature</i>. 2025;638(8051). doi:<a href="https://doi.org/10.1038/s41586-024-08530-6">10.1038/s41586-024-08530-6</a>
  apa: Sobarzo Ponce, J. C. A., Pertl, F., Balazs, D., Costanzo, T., Sauer, M., Foelske,
    A., … Waitukaitis, S. R. (2025). Spontaneous ordering of identical materials into
    a triboelectric series. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-024-08530-6">https://doi.org/10.1038/s41586-024-08530-6</a>
  chicago: Sobarzo Ponce, Juan Carlos A, Felix Pertl, Daniel Balazs, Tommaso Costanzo,
    Markus Sauer, Annette Foelske, Markus Ostermann, et al. “Spontaneous Ordering
    of Identical Materials into a Triboelectric Series.” <i>Nature</i>. Springer Nature,
    2025. <a href="https://doi.org/10.1038/s41586-024-08530-6">https://doi.org/10.1038/s41586-024-08530-6</a>.
  ieee: J. C. A. Sobarzo Ponce <i>et al.</i>, “Spontaneous ordering of identical materials
    into a triboelectric series,” <i>Nature</i>, vol. 638, no. 8051. Springer Nature,
    2025.
  ista: Sobarzo Ponce JCA, Pertl F, Balazs D, Costanzo T, Sauer M, Foelske A, Ostermann
    M, Pichler CM, Wang Y, Nagata Y, Bonn M, Waitukaitis SR. 2025. Spontaneous ordering
    of identical materials into a triboelectric series. Nature. 638(8051), 664–669.
  mla: Sobarzo Ponce, Juan Carlos A., et al. “Spontaneous Ordering of Identical Materials
    into a Triboelectric Series.” <i>Nature</i>, vol. 638, no. 8051, 664–669, Springer
    Nature, 2025, doi:<a href="https://doi.org/10.1038/s41586-024-08530-6">10.1038/s41586-024-08530-6</a>.
  short: J.C.A. Sobarzo Ponce, F. Pertl, D. Balazs, T. Costanzo, M. Sauer, A. Foelske,
    M. Ostermann, C.M. Pichler, Y. Wang, Y. Nagata, M. Bonn, S.R. Waitukaitis, Nature
    638 (2025).
corr_author: '1'
date_created: 2025-03-02T23:01:52Z
date_published: 2025-02-20T00:00:00Z
date_updated: 2026-08-27T11:42:43Z
day: '20'
ddc:
- '530'
department:
- _id: ScWa
- _id: LifeSc
- _id: EM-Fac
doi: 10.1038/s41586-024-08530-6
ec_funded: 1
external_id:
  isi:
  - '001428076100015'
  pmid:
  - '39972227'
file:
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  content_type: application/pdf
  creator: dernst
  date_created: 2025-03-04T10:05:18Z
  date_updated: 2025-03-04T10:05:18Z
  file_id: '19289'
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file_date_updated: 2025-03-04T10:05:18Z
has_accepted_license: '1'
intvolume: '       638'
isi: 1
issue: '8051'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
  call_identifier: H2020
  grant_number: '949120'
  name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://ista.ac.at/en/news/an-electrifying-turn-in-an-age-old-quest/
  record:
  - id: '20203'
    relation: dissertation_contains
    status: public
  - id: '22684'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Spontaneous ordering of identical materials into a triboelectric series
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 638
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20481'
abstract:
- lang: eng
  text: 'Kelvin probe force microscopy (KPFM) is widely used in stationary and dynamic
    studies of contact electrification. An obvious question that connects these two
    has been overlooked: when are charge dynamics too fast for stationary studies
    to be meaningful? Using a rapid transfer system to quickly perform KPFM after
    contact, we find the dynamics are too fast in all but the best insulators. Our
    data further suggest that dynamics are caused by bulk as opposed to surface conductivity,
    and that charge-transfer heterogeneity is less prevalent than previously suggested.'
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: LifeSc
acknowledgement: This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (Grant agreement No. 949120). This research was supported by the Scientific Service
  Units of The Institute of Science and Technology Austria (ISTA) through resources
  provided by the Miba Machine Shop, the Nanofabrication Facility and Lab Support
  Facility.
article_number: '146202'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Felix
  full_name: Pertl, Felix
  id: 6313aec0-15b2-11ec-abd3-ed67d16139af
  last_name: Pertl
  orcid: 0000-0003-0463-5794
- first_name: Isaac C
  full_name: Lenton, Isaac C
  id: a550210f-223c-11ec-8182-e2d45e817efb
  last_name: Lenton
  orcid: 0000-0002-5010-6984
- first_name: Tobias
  full_name: Cramer, Tobias
  last_name: Cramer
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
citation:
  ama: 'Pertl F, Lenton IC, Cramer T, Waitukaitis SR. No time for surface charge:
    How bulk conductivity hides charge patterns from Kelvin probe force microscopy
    in contact-electrified surfaces. <i>Physical Review Letters</i>. 2025;135(14).
    doi:<a href="https://doi.org/10.1103/lcsm-xxty">10.1103/lcsm-xxty</a>'
  apa: 'Pertl, F., Lenton, I. C., Cramer, T., &#38; Waitukaitis, S. R. (2025). No
    time for surface charge: How bulk conductivity hides charge patterns from Kelvin
    probe force microscopy in contact-electrified surfaces. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/lcsm-xxty">https://doi.org/10.1103/lcsm-xxty</a>'
  chicago: 'Pertl, Felix, Isaac C Lenton, Tobias Cramer, and Scott R Waitukaitis.
    “No Time for Surface Charge: How Bulk Conductivity Hides Charge Patterns from
    Kelvin Probe Force Microscopy in Contact-Electrified Surfaces.” <i>Physical Review
    Letters</i>. American Physical Society, 2025. <a href="https://doi.org/10.1103/lcsm-xxty">https://doi.org/10.1103/lcsm-xxty</a>.'
  ieee: 'F. Pertl, I. C. Lenton, T. Cramer, and S. R. Waitukaitis, “No time for surface
    charge: How bulk conductivity hides charge patterns from Kelvin probe force microscopy
    in contact-electrified surfaces,” <i>Physical Review Letters</i>, vol. 135, no.
    14. American Physical Society, 2025.'
  ista: 'Pertl F, Lenton IC, Cramer T, Waitukaitis SR. 2025. No time for surface charge:
    How bulk conductivity hides charge patterns from Kelvin probe force microscopy
    in contact-electrified surfaces. Physical Review Letters. 135(14), 146202.'
  mla: 'Pertl, Felix, et al. “No Time for Surface Charge: How Bulk Conductivity Hides
    Charge Patterns from Kelvin Probe Force Microscopy in Contact-Electrified Surfaces.”
    <i>Physical Review Letters</i>, vol. 135, no. 14, 146202, American Physical Society,
    2025, doi:<a href="https://doi.org/10.1103/lcsm-xxty">10.1103/lcsm-xxty</a>.'
  short: F. Pertl, I.C. Lenton, T. Cramer, S.R. Waitukaitis, Physical Review Letters
    135 (2025).
corr_author: '1'
date_created: 2025-10-16T13:13:29Z
date_published: 2025-09-30T00:00:00Z
date_updated: 2026-08-27T11:42:43Z
day: '30'
ddc:
- '530'
department:
- _id: ScWa
doi: 10.1103/lcsm-xxty
ec_funded: 1
external_id:
  arxiv:
  - '2502.12718'
  isi:
  - '001587263900003'
file:
- access_level: open_access
  checksum: 7e45e89b8db0b7f01e63185c68e4b0f9
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-23T09:32:31Z
  date_updated: 2025-10-23T09:32:31Z
  file_id: '20522'
  file_name: 2025_PhysReviewLetters_Pertl.pdf
  file_size: 1692251
  relation: main_file
  success: 1
file_date_updated: 2025-10-23T09:32:31Z
has_accepted_license: '1'
intvolume: '       135'
isi: 1
issue: '14'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
  call_identifier: H2020
  grant_number: '949120'
  name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '20523'
    relation: research_data
    status: public
  - id: '22684'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'No time for surface charge: How bulk conductivity hides charge patterns from
  Kelvin probe force microscopy in contact-electrified surfaces'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 135
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20452'
abstract:
- lang: eng
  text: Accurate modeling of long-range forces is critical in atomistic simulations,
    as they play a central role in determining the properties of material and chemical
    systems. However, standard machine learning interatomic potentials (MLIPs) often
    rely on short-range approximations, limiting their applicability to systems with
    significant electrostatics and dispersion forces. We recently introduced the Latent
    Ewald Summation (LES) method, which captures long-range electrostatics without
    explicitly learning atomic charges or charge equilibration. We benchmark LES on
    diverse and challenging systems, including charged molecules, ionic liquids, electrolyte
    solutions, polar dipeptides, surface adsorption, electrolyte/solid interfaces,
    and solid-solid interfaces. Here we show that LES can reproduce the exact atomic
    charges for classical systems with fixed charges and can infer dipole and quadrupole
    moments, as well as the dipole derivative with respect to atomic positions, for
    quantum mechanical systems. Moreover, LES can achieve better accuracy in energy
    and force predictions compared to methods that explicitly learn from charges.
acknowledgement: We thank Chunyi Zhang for providing the TiO2(101)/NaCl+NaOH+HCl(aq)
  dataset and for useful discussions. We thank Jia-Xin Zhu for providing the Pt(111)/KF(aq)
  dataset. We thank Tsz Wai Ko and Jonas Finkler for useful discussions and for the
  DFT-optimized Au2-MgO(001) structures. We thank Junmin Chen for discussions. D.K
  and B.C. acknowledge funding from Toyota Research Institute Synthesis Advanced Research
  Challenge. D.S.K. and P.Z. acknowledge funding from BIDMaP Postdoctoral Fellowship.
article_number: '8763'
article_processing_charge: Yes
article_type: original
author:
- first_name: Daniel S.
  full_name: King, Daniel S.
  last_name: King
- first_name: Dongjin
  full_name: Kim, Dongjin
  last_name: Kim
- first_name: Peichen
  full_name: Zhong, Peichen
  last_name: Zhong
- first_name: Bingqing
  full_name: Cheng, Bingqing
  id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
  last_name: Cheng
  orcid: 0000-0002-3584-9632
citation:
  ama: King DS, Kim D, Zhong P, Cheng B. Machine learning of charges and long-range
    interactions from energies and forces. <i>Nature Communications</i>. 2025;16.
    doi:<a href="https://doi.org/10.1038/s41467-025-63852-x">10.1038/s41467-025-63852-x</a>
  apa: King, D. S., Kim, D., Zhong, P., &#38; Cheng, B. (2025). Machine learning of
    charges and long-range interactions from energies and forces. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-025-63852-x">https://doi.org/10.1038/s41467-025-63852-x</a>
  chicago: King, Daniel S., Dongjin Kim, Peichen Zhong, and Bingqing Cheng. “Machine
    Learning of Charges and Long-Range Interactions from Energies and Forces.” <i>Nature
    Communications</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s41467-025-63852-x">https://doi.org/10.1038/s41467-025-63852-x</a>.
  ieee: D. S. King, D. Kim, P. Zhong, and B. Cheng, “Machine learning of charges and
    long-range interactions from energies and forces,” <i>Nature Communications</i>,
    vol. 16. Springer Nature, 2025.
  ista: King DS, Kim D, Zhong P, Cheng B. 2025. Machine learning of charges and long-range
    interactions from energies and forces. Nature Communications. 16, 8763.
  mla: King, Daniel S., et al. “Machine Learning of Charges and Long-Range Interactions
    from Energies and Forces.” <i>Nature Communications</i>, vol. 16, 8763, Springer
    Nature, 2025, doi:<a href="https://doi.org/10.1038/s41467-025-63852-x">10.1038/s41467-025-63852-x</a>.
  short: D.S. King, D. Kim, P. Zhong, B. Cheng, Nature Communications 16 (2025).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: The training sets, training scripts, MD input files, and
  trained CACE potentials are available at https://github.com/BingqingCheng/cace-lr-fit;
  see https://doi.org/10.5281/zenodo.16415061. Source data for all figures are provided
  with this paper. Source data are provided with this paper.
date_created: 2025-10-12T22:01:25Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2026-08-27T12:16:47Z
day: '01'
ddc:
- '000'
department:
- _id: BiCh
doi: 10.1038/s41467-025-63852-x
external_id:
  isi:
  - '001586620700015'
  pmid:
  - '41034200'
file:
- access_level: open_access
  checksum: 34b6005d349bbff85839c4e51d6c8725
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T07:54:51Z
  date_updated: 2025-10-13T07:54:51Z
  file_id: '20460'
  file_name: 2025_NatureComm_King.pdf
  file_size: 4907055
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T07:54:51Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
language:
- iso: eng
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publication: Nature Communications
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publisher: Springer Nature
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title: Machine learning of charges and long-range interactions from energies and forces
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author:
- first_name: Bingqing
  full_name: Cheng, Bingqing
  last_name: Cheng
- first_name: Daniel
  full_name: King, Daniel
  last_name: King
- first_name: Dongjin
  full_name: Kim, Dongjin
  last_name: Kim
- first_name: Peichen
  full_name: Zhong, Peichen
  last_name: Zhong
citation:
  ama: 'Cheng B, King D, Kim D, Zhong P. BingqingCheng/cace-lr-fit: V0. 2025. doi:<a
    href="https://doi.org/10.5281/zenodo.16415060">10.5281/zenodo.16415060</a>'
  apa: 'Cheng, B., King, D., Kim, D., &#38; Zhong, P. (2025). BingqingCheng/cace-lr-fit:
    V0. Repository. <a href="https://doi.org/10.5281/zenodo.16415060">https://doi.org/10.5281/zenodo.16415060</a>'
  chicago: 'Cheng, Bingqing, Daniel King, Dongjin Kim, and Peichen Zhong. “BingqingCheng/Cace-Lr-Fit:
    V0.” Repository, 2025. <a href="https://doi.org/10.5281/zenodo.16415060">https://doi.org/10.5281/zenodo.16415060</a>.'
  ieee: 'B. Cheng, D. King, D. Kim, and P. Zhong, “BingqingCheng/cace-lr-fit: V0.”
    Repository, 2025.'
  ista: 'Cheng B, King D, Kim D, Zhong P. 2025. BingqingCheng/cace-lr-fit: V0, Repository,
    <a href="https://doi.org/10.5281/zenodo.16415060">10.5281/zenodo.16415060</a>.'
  mla: 'Cheng, Bingqing, et al. <i>BingqingCheng/Cace-Lr-Fit: V0</i>. Repository,
    2025, doi:<a href="https://doi.org/10.5281/zenodo.16415060">10.5281/zenodo.16415060</a>.'
  short: B. Cheng, D. King, D. Kim, P. Zhong, (2025).
date_created: 2026-08-27T12:13:55Z
date_published: 2025-07-24T00:00:00Z
date_updated: 2026-08-27T12:16:48Z
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doi: 10.5281/zenodo.16415060
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abstract:
- lang: eng
  text: "The overarching goal of this thesis is to break down the complexity of turbulent
    flows in terms of enumerable, coherent structures and patterns. In a five-paper
    series, we adopt a variety of perspectives and techniques to relate the properties
    of systems of increasing complexity to their underlying coherent structures. \r\n\r\nInitially,
    we take a dynamical systems point of view, seeing turbulent flow as a chaotic
    trajectory bouncing between exact unstable solutions of the underlying equations
    of motion. Using persistent homology, the main tool of topological data analysis
    capturing the persistence across scales of topological features in a point cloud,
    we introduce a method that quantifies visits of turbulent trajectories to unstable
    time-periodic solutions, also called periodic orbits. We demonstrate this method
    first in the Rössler and Kuramoto–Sivashinsky systems. Using this method in 3D
    Kolmogorov flow, we extract a Markov chain from turbulent data, where each node
    corresponds to the neighbourhood of a periodic orbit. The invariant distribution
    of this Markov chain reproduces expectation values on turbulent data when it is
    used to weight averages on the respective periodic orbits.\r\n\r\nIn more realistic,
    wall-bounded settings, such as plane-Couette flow (pcf) driven by the relative
    motion of the walls, or plane-Poiseuille flow (ppf) driven by a pressure gradient,
    finding exact solutions is difficult. We use dynamic mode decomposition (DMD),
    a dimensionality reduction method for sequential data, to identify and approximate
    low-dimensional dynamics without knowing any exact solutions. Most spatially-extended
    systems are equivariant under translations, and in such cases spatial drifts dominate
    DMD, hindering its use in the search for and modelling of low-dimensional dynamics.
    We augment DMD with a symmetry reduction method trained on turbulent data to stop
    it from seeing translations as a feature, improving its ability to extract dynamical
    information in translation-equivariant systems. We find segments of turbulent
    trajectories that linearize well with their symmetry-reduced DMD spectra, akin
    to dynamics near exact solutions. Searching for harmonics in the spectra gives
    leads for periodic orbits with spatial drifts, one of which converges to a new
    solution.\r\n\r\nIn larger domains, turbulence can localize and coexist with surrounding
    laminar flow. Our preceding approaches are global, taking all of a domain into
    account at once, and cannot readily treat each localized patch individually. Working
    first in a minimal oblique domain that can host a single 1D-localized turbulent
    patch, we find that turbulence in ppf is connected to a stable periodic orbit
    at a flow velocity much lower than when turbulence is first onset. We show that,
    well in advance of sustained turbulence, chaos sets in explosively, and for long
    time horizons, time series are consistent with that of a random process.\r\n\r\nFinally,
    in much larger domains, we study and compare 2D-localized turbulence that appears
    as large-scale inclined structures, called stripes, in ppf and pcf. While appearing
    similar, we find that stripes in these two settings differ significantly in terms
    of how they sustain themselves, and in higher velocities, how they proliferate."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The work in this thesis was supported by a grant from the Simons
  Foundation (662960, BH).\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Gökhan
  full_name: Yalniz, Gökhan
  id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
  last_name: Yalniz
  orcid: 0000-0002-8490-9312
citation:
  ama: 'Yalniz G. Transition to turbulence: Data-, solution-, and pattern-driven approaches.
    2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>'
  apa: 'Yalniz, G. (2025). <i>Transition to turbulence: Data-, solution-, and pattern-driven
    approaches</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>'
  chicago: 'Yalniz, Gökhan. “Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches.” Institute of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-19684">https://doi.org/10.15479/AT-ISTA-19684</a>.'
  ieee: 'G. Yalniz, “Transition to turbulence: Data-, solution-, and pattern-driven
    approaches,” Institute of Science and Technology Austria, 2025.'
  ista: 'Yalniz G. 2025. Transition to turbulence: Data-, solution-, and pattern-driven
    approaches. Institute of Science and Technology Austria.'
  mla: 'Yalniz, Gökhan. <i>Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches</i>. Institute of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-19684">10.15479/AT-ISTA-19684</a>.'
  short: 'G. Yalniz, Transition to Turbulence: Data-, Solution-, and Pattern-Driven
    Approaches, Institute of Science and Technology Austria, 2025.'
corr_author: '1'
date_created: 2025-05-12T15:12:28Z
date_published: 2025-05-13T00:00:00Z
date_updated: 2026-09-02T08:16:32Z
day: '13'
ddc:
- '514'
- '519'
- '532'
- '004'
degree_awarded: PhD
department:
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- _id: BjHo
doi: 10.15479/AT-ISTA-19684
doi_confirm: '1'
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  description: '3D visualizations of the turbulent flow (left) and the periodic orbits
    (middle) that are being shadowed along with the local state space projections
    (right) onto the principal components of the respective periodic orbit. Shown
    here are the isosurfaces of velocity (red/blue: ±95% of the instantaneous maximum)
    and vorticity (purple/green: ±65% of the instantaneous maximum) in the x-direction.
    Markers along the projections are in sync with the 3D visualizations. The movie
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  description: 'Turbulent flow (left) in HKW domain and its symmetry reduction (right).
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  description: 'Turbulent flow (left) in P2K domain and its symmetry reduction (right).
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  description: 'Relative periodic orbit RPO_79.4 (left) of the plane-Couette flow
    (HKW domain) and its symmetry reduction (right). Shown here are the isosurfaces
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  description: 'Symmetry-reduced flow (left), its SRDMD approximation (middle), and
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    3.6 (b) and figure 3.8 (b)). Shown here are the isosurfaces of streamwise velocity
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  description: Movie demonstrating the quasi-steady Reynolds number descent from turbulence
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  description: Streamwise velocity fluctuations (from laminar) of plane-Couette flow
    (Re^C =335) at the y = 0 wall-normal plane in coordinates stationary with respect
    to the bulk velocity. Here, x is the streamwise direction (the wall at y = 1 moves
    to the right) and z is the spanwise direction. Time is in advectime time units.
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  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P =660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the bulk velocity. Here, x is the streamwise direction (the mean negative
    pressure gradient is to the right) and z is the spanwise direction. Time is in
    advectime time units. Shown is the full (L_x = L_z = 400) domain.
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  description: Streamwise velocity fluctuations (from laminar) of plane-Poiseuille
    flow (Re^P=660) at the y = 0.5 wall-normal plane in coordinates stationary with
    respect to the average velocity of the downstream tip of the stripe. Here, x is
    the streamwise direction (the mean negative pressure gradient is to the right)
    and z is the spanwise direction. Time is in advectime time units. Shown is a zoom-in
    of the full (L_x = L_z) domain.
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  grant_number: '662960'
  name: Revisiting the Turbulence Problem Using Statistical Mechanics
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publisher: Institute of Science and Technology Austria
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  orcid: 0000-0003-2057-2754
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type: dissertation
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...
