---
OA_type: closed access
_id: '21806'
abstract:
- lang: eng
text: Light-responsive liquid crystal elastomer networks (LCNs) have received significant
interest due to their potential application in soft robotics and shape-morphing
devices. Here, we present a systematic examination of light-responsive LCNs prepared
using a catalyst-free Diels–Alder cycloaddition and a new azobenzene functionalized
monomer for main-chain incorporation. The networks have robust mechanical stiffness
that can be reversibly modulated by 1 GPa by turning the UV light on and off.
This study highlights the contribution of photothermal softening to reversibly
control rheological properties of the newly developed LCNs and demonstrates the
ability to tune the modulus on demand. We believe this work will guide future
developments of light-responsive LCNs based on the newly developed Diels–Alder
cycloaddition.
article_processing_charge: No
article_type: original
author:
- first_name: Minwook
full_name: Park, Minwook
last_name: Park
- first_name: Jesus
full_name: Guillen Campos, Jesus
last_name: Guillen Campos
- first_name: Friedrich J
full_name: Stricker, Friedrich J
id: 7aca2cfc-46cf-11f0-abd3-8c96b5186745
last_name: Stricker
- first_name: Javier
full_name: Read de Alaniz, Javier
last_name: Read de Alaniz
citation:
ama: Park M, Guillen Campos J, Stricker FJ, Read de Alaniz J. Photo-responsive Diels-Alder
based azobenzene-functionalized main-chain liquid crystal networks. Journal
of Materials Chemistry C. 2024;12(31):11976-11981. doi:10.1039/d4tc01281j
apa: Park, M., Guillen Campos, J., Stricker, F. J., & Read de Alaniz, J. (2024).
Photo-responsive Diels-Alder based azobenzene-functionalized main-chain liquid
crystal networks. Journal of Materials Chemistry C. Royal Society of Chemistry.
https://doi.org/10.1039/d4tc01281j
chicago: Park, Minwook, Jesus Guillen Campos, Friedrich J Stricker, and Javier Read
de Alaniz. “Photo-Responsive Diels-Alder Based Azobenzene-Functionalized Main-Chain
Liquid Crystal Networks.” Journal of Materials Chemistry C. Royal Society
of Chemistry, 2024. https://doi.org/10.1039/d4tc01281j.
ieee: M. Park, J. Guillen Campos, F. J. Stricker, and J. Read de Alaniz, “Photo-responsive
Diels-Alder based azobenzene-functionalized main-chain liquid crystal networks,”
Journal of Materials Chemistry C, vol. 12, no. 31. Royal Society of Chemistry,
pp. 11976–11981, 2024.
ista: Park M, Guillen Campos J, Stricker FJ, Read de Alaniz J. 2024. Photo-responsive
Diels-Alder based azobenzene-functionalized main-chain liquid crystal networks.
Journal of Materials Chemistry C. 12(31), 11976–11981.
mla: Park, Minwook, et al. “Photo-Responsive Diels-Alder Based Azobenzene-Functionalized
Main-Chain Liquid Crystal Networks.” Journal of Materials Chemistry C,
vol. 12, no. 31, Royal Society of Chemistry, 2024, pp. 11976–81, doi:10.1039/d4tc01281j.
short: M. Park, J. Guillen Campos, F.J. Stricker, J. Read de Alaniz, Journal of
Materials Chemistry C 12 (2024) 11976–11981.
date_created: 2026-05-06T10:43:33Z
date_published: 2024-07-10T00:00:00Z
date_updated: 2026-05-12T06:50:12Z
day: '10'
ddc:
- '540'
doi: 10.1039/d4tc01281j
extern: '1'
intvolume: ' 12'
issue: '31'
language:
- iso: eng
month: '07'
oa_version: None
page: 11976-11981
publication: Journal of Materials Chemistry C
publication_identifier:
eissn:
- 2050-7534
issnl:
- 2050-7526
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photo-responsive Diels-Alder based azobenzene-functionalized main-chain liquid
crystal networks
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 12
year: '2024'
...
---
OA_type: closed access
_id: '21817'
abstract:
- lang: eng
text: 'Ambidirectionality, which is the ability of structural elements to move beyond
a reference state in two opposite directions, is common in nature. However, conventional
soft materials are typically limited to a single, unidirectional deformation unless
complex hybrid constructs are used. We exploited the combination of mesogen self-assembly,
polymer chain elasticity, and polymerization-induced stress to design liquid crystalline
elastomers that exhibit two mesophases: chevron smectic C (cSmC) and smectic A
(SmA). Inducing the cSmC-SmA–isotropic phase transition led to an unusual inversion
of the strain field in the microstructure, resulting in opposite deformation modes
(e.g., consecutive shrinkage or expansion and right-handed or left-handed twisting
and tilting in opposite directions) and high-frequency nonmonotonic oscillations.
This ambidirectional movement is scalable and can be used to generate Gaussian
transformations at the macroscale.'
article_processing_charge: No
article_type: original
author:
- first_name: Yuxing
full_name: Yao, Yuxing
last_name: Yao
- first_name: Atalaya Milan
full_name: Wilborn, Atalaya Milan
last_name: Wilborn
- first_name: Baptiste
full_name: Lemaire, Baptiste
last_name: Lemaire
- first_name: Foteini
full_name: Trigka, Foteini
last_name: Trigka
- first_name: Friedrich J
full_name: Stricker, Friedrich J
id: 7aca2cfc-46cf-11f0-abd3-8c96b5186745
last_name: Stricker
- first_name: Alan H.
full_name: Weible, Alan H.
last_name: Weible
- first_name: Shucong
full_name: Li, Shucong
last_name: Li
- first_name: Robert K. A.
full_name: Bennett, Robert K. A.
last_name: Bennett
- first_name: Tung Chun
full_name: Cheung, Tung Chun
last_name: Cheung
- first_name: Alison
full_name: Grinthal, Alison
last_name: Grinthal
- first_name: Mikhail
full_name: Zhernenkov, Mikhail
last_name: Zhernenkov
- first_name: Guillaume
full_name: Freychet, Guillaume
last_name: Freychet
- first_name: Patryk
full_name: Wąsik, Patryk
last_name: Wąsik
- first_name: Boris
full_name: Kozinsky, Boris
last_name: Kozinsky
- first_name: Michael M.
full_name: Lerch, Michael M.
last_name: Lerch
- first_name: Xiaoguang
full_name: Wang, Xiaoguang
last_name: Wang
- first_name: Joanna
full_name: Aizenberg, Joanna
last_name: Aizenberg
citation:
ama: Yao Y, Wilborn AM, Lemaire B, et al. Programming liquid crystal elastomers
for multistep ambidirectional deformability. Science. 2024;386(6726):1161-1168.
doi:10.1126/science.adq6434
apa: Yao, Y., Wilborn, A. M., Lemaire, B., Trigka, F., Stricker, F. J., Weible,
A. H., … Aizenberg, J. (2024). Programming liquid crystal elastomers for multistep
ambidirectional deformability. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.adq6434
chicago: Yao, Yuxing, Atalaya Milan Wilborn, Baptiste Lemaire, Foteini Trigka, Friedrich
J Stricker, Alan H. Weible, Shucong Li, et al. “Programming Liquid Crystal Elastomers
for Multistep Ambidirectional Deformability.” Science. American Association
for the Advancement of Science, 2024. https://doi.org/10.1126/science.adq6434.
ieee: Y. Yao et al., “Programming liquid crystal elastomers for multistep
ambidirectional deformability,” Science, vol. 386, no. 6726. American Association
for the Advancement of Science, pp. 1161–1168, 2024.
ista: Yao Y, Wilborn AM, Lemaire B, Trigka F, Stricker FJ, Weible AH, Li S, Bennett
RKA, Cheung TC, Grinthal A, Zhernenkov M, Freychet G, Wąsik P, Kozinsky B, Lerch
MM, Wang X, Aizenberg J. 2024. Programming liquid crystal elastomers for multistep
ambidirectional deformability. Science. 386(6726), 1161–1168.
mla: Yao, Yuxing, et al. “Programming Liquid Crystal Elastomers for Multistep Ambidirectional
Deformability.” Science, vol. 386, no. 6726, American Association for the
Advancement of Science, 2024, pp. 1161–68, doi:10.1126/science.adq6434.
short: Y. Yao, A.M. Wilborn, B. Lemaire, F. Trigka, F.J. Stricker, A.H. Weible,
S. Li, R.K.A. Bennett, T.C. Cheung, A. Grinthal, M. Zhernenkov, G. Freychet, P.
Wąsik, B. Kozinsky, M.M. Lerch, X. Wang, J. Aizenberg, Science 386 (2024) 1161–1168.
date_created: 2026-05-06T10:54:51Z
date_published: 2024-12-06T00:00:00Z
date_updated: 2026-05-12T09:48:12Z
day: '06'
ddc:
- '540'
doi: 10.1126/science.adq6434
extern: '1'
external_id:
pmid:
- '39636998'
intvolume: ' 386'
issue: '6726'
language:
- iso: eng
month: '12'
oa_version: None
page: 1161-1168
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Programming liquid crystal elastomers for multistep ambidirectional deformability
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 386
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21913'
abstract:
- lang: eng
text: 'The HIRA histone chaperone complex is comprised of four protein subunits:
HIRA, UBN1, CABIN1, and transiently associated ASF1a. All four subunits have been
demonstrated to play a role in the deposition of the histone variant H3.3 onto
areas of actively transcribed euchromatin in cells. The mechanism by which these
subunits function together to drive histone deposition has remained poorly understood.
Here we present biochemical and biophysical data supporting a model whereby ASF1a
delivers histone H3.3/H4 dimers to the HIRA complex, H3.3/H4 tetramerization drives
the association of two HIRA/UBN1 complexes, and the affinity of the histones for
DNA drives release of ASF1a and subsequent histone deposition. These findings
have implications for understanding how other histone chaperone complexes may
mediate histone deposition.'
acknowledgement: We would like to acknowledge Elliot Dean and Christina Freeman for
technical assistance with recombinant protein expression in insect cells and members
of the Marmorstein laboratory for many discussions related to this work. Schematic
Figures were created with BioRender.com.
article_number: '107604'
article_processing_charge: Yes
article_type: original
author:
- first_name: Austin
full_name: Vogt, Austin
last_name: Vogt
- first_name: Mary
full_name: Szurgot, Mary
last_name: Szurgot
- first_name: Lauren
full_name: Gardner, Lauren
id: f9dedd98-6d15-11f0-88a5-a7b4143fdec5
last_name: Gardner
orcid: 0009-0000-5733-1546
- first_name: David C.
full_name: Schultz, David C.
last_name: Schultz
- first_name: Ronen
full_name: Marmorstein, Ronen
last_name: Marmorstein
citation:
ama: Vogt A, Szurgot M, Gardner L, Schultz DC, Marmorstein R. HIRA complex deposition
of histone H3.3 is driven by histone tetramerization and histone-DNA binding.
Journal of Biological Chemistry. 2024;300(9). doi:10.1016/j.jbc.2024.107604
apa: Vogt, A., Szurgot, M., Gardner, L., Schultz, D. C., & Marmorstein, R. (2024).
HIRA complex deposition of histone H3.3 is driven by histone tetramerization and
histone-DNA binding. Journal of Biological Chemistry. Elsevier. https://doi.org/10.1016/j.jbc.2024.107604
chicago: Vogt, Austin, Mary Szurgot, Lauren Gardner, David C. Schultz, and Ronen
Marmorstein. “HIRA Complex Deposition of Histone H3.3 Is Driven by Histone Tetramerization
and Histone-DNA Binding.” Journal of Biological Chemistry. Elsevier, 2024.
https://doi.org/10.1016/j.jbc.2024.107604.
ieee: A. Vogt, M. Szurgot, L. Gardner, D. C. Schultz, and R. Marmorstein, “HIRA
complex deposition of histone H3.3 is driven by histone tetramerization and histone-DNA
binding,” Journal of Biological Chemistry, vol. 300, no. 9. Elsevier, 2024.
ista: Vogt A, Szurgot M, Gardner L, Schultz DC, Marmorstein R. 2024. HIRA complex
deposition of histone H3.3 is driven by histone tetramerization and histone-DNA
binding. Journal of Biological Chemistry. 300(9), 107604.
mla: Vogt, Austin, et al. “HIRA Complex Deposition of Histone H3.3 Is Driven by
Histone Tetramerization and Histone-DNA Binding.” Journal of Biological Chemistry,
vol. 300, no. 9, 107604, Elsevier, 2024, doi:10.1016/j.jbc.2024.107604.
short: A. Vogt, M. Szurgot, L. Gardner, D.C. Schultz, R. Marmorstein, Journal of
Biological Chemistry 300 (2024).
date_created: 2026-05-24T08:25:45Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2026-06-02T14:52:50Z
day: '01'
ddc:
- '572'
doi: 10.1016/j.jbc.2024.107604
extern: '1'
external_id:
pmid:
- '39059488'
has_accepted_license: '1'
intvolume: ' 300'
issue: '9'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.jbc.2024.107604
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Biological Chemistry
publication_identifier:
eissn:
- 1083-351X
issn:
- 0021-9258
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: HIRA complex deposition of histone H3.3 is driven by histone tetramerization
and histone-DNA binding
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 300
year: '2024'
...
---
OA_type: green
_id: '21967'
abstract:
- lang: eng
text: "Selection against deleterious mutations, called purifying selection, plays
a central role in evolution and acts in all populations. It is known that the
genetic patterns observed in genomic regions undergoing purifying selection differ
from those resulting from neutral evolution. However, a comprehensive understanding
of the underlying mechanisms shaping those patterns is still lacking.\r\n\r\nIn
the present work, we use simulations combined with a genealogical approach to
identify the effect of purifying selection on the ancestry and thus on the genetic
diversity. Our analysis relies on the postulate that the genealogy belongs to
the universality class of Beta-coalescents. Under this assumption, we derive statistics
measuring the distortion of the genealogy. This approach allows us to consider
a wide range of regimes (i.e. arbitrary selection and mutation strengths) and
uncover a rich phase diagram. We find that, for strong selection, the limiting
genealogy is given by Kingman’s coalescent on a polynomial timescale. As selection
gets weaker, Muller’s ratchet starts operating, setting off the emergence of multiple
mergers in the genealogical structures. Our results show that while multiple-merger
coalescents are often interpreted as the signature of selective sweeps in rapidly
adapting populations, these structures can also appear in the context of Muller’s
ratchet."
acknowledgement: This work was supported by the Austrian Academy of Science, DOC fellowship
No 26293 (K.K.) and the European Union’s Horizon 2020 research and innovation programme
under the Marie Skłodowska-Curie grant agreement No 101034413 (J.T.). Simulations
were performed on the ISTA High-performance Computing Cluster.
article_processing_charge: No
author:
- first_name: Kseniia
full_name: Khudiakova, Kseniia
id: 4E6DC800-AE37-11E9-AC72-31CAE5697425
last_name: Khudiakova
orcid: 0000-0002-6246-1465
- first_name: Florin
full_name: Boenkost, Florin
last_name: Boenkost
- first_name: Julie N
full_name: Tourniaire, Julie N
id: 5dc06dd8-8e51-11ec-9170-8d9c450cc216
last_name: Tourniaire
citation:
ama: Khudiakova K, Boenkost F, Tourniaire JN. Genealogies under purifying selection.
bioRxiv. doi:10.1101/2024.10.15.618444
apa: Khudiakova, K., Boenkost, F., & Tourniaire, J. N. (n.d.). Genealogies under
purifying selection. bioRxiv. https://doi.org/10.1101/2024.10.15.618444
chicago: Khudiakova, Kseniia, Florin Boenkost, and Julie N Tourniaire. “Genealogies
under Purifying Selection.” BioRxiv, n.d. https://doi.org/10.1101/2024.10.15.618444.
ieee: K. Khudiakova, F. Boenkost, and J. N. Tourniaire, “Genealogies under purifying
selection,” bioRxiv. .
ista: Khudiakova K, Boenkost F, Tourniaire JN. Genealogies under purifying selection.
bioRxiv, 10.1101/2024.10.15.618444.
mla: Khudiakova, Kseniia, et al. “Genealogies under Purifying Selection.” BioRxiv,
doi:10.1101/2024.10.15.618444.
short: K. Khudiakova, F. Boenkost, J.N. Tourniaire, BioRxiv (n.d.).
corr_author: '1'
date_created: 2026-06-09T12:14:08Z
date_published: 2024-10-18T00:00:00Z
date_updated: 2026-06-12T12:43:34Z
day: '18'
department:
- _id: NiBa
- _id: JaMa
doi: 10.1101/2024.10.15.618444
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2024.10.15.618444
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 34d33d68-11ca-11ed-8bc3-ec13763c0ca8
grant_number: '26293'
name: The impact of deleterious mutations on small populations
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: bioRxiv
publication_status: draft
related_material:
record:
- id: '21918'
relation: dissertation_contains
status: public
status: public
title: Genealogies under purifying selection
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '13974'
abstract:
- lang: eng
text: The Tverberg theorem is one of the cornerstones of discrete geometry. It states
that, given a set X of at least (d+1)(r−1)+1 points in Rd, one can find a partition
X=X1∪⋯∪Xr of X, such that the convex hulls of the Xi, i=1,…,r, all share a common
point. In this paper, we prove a trengthening of this theorem that guarantees
a partition which, in addition to the above, has the property that the boundaries
of full-dimensional convex hulls have pairwise nonempty intersections. Possible
generalizations and algorithmic aspects are also discussed. As a concrete application,
we show that any n points in the plane in general position span ⌊n/3⌋ vertex-disjoint
triangles that are pairwise crossing, meaning that their boundaries have pairwise
nonempty intersections; this number is clearly best possible. A previous result
of Álvarez-Rebollar et al. guarantees ⌊n/6⌋pairwise crossing triangles. Our result
generalizes to a result about simplices in Rd, d≥2.
acknowledgement: "Part of the research leading to this paper was done during the 16th
Gremo Workshop on Open Problems (GWOP), Waltensburg, Switzerland, June 12–16, 2018.
We thank Patrick Schnider for suggesting the problem, and Stefan Felsner, Malte
Milatz, and Emo Welzl for fruitful discussions during the workshop. We also thank
Stefan Felsner and Manfred Scheucher for finding, communicating the example from
Sect. 3.3, and the kind permission to include their visualization of the point set.
We thank Dömötör Pálvölgyi, the SoCG reviewers, and DCG reviewers for various helpful
comments.\r\nR. Fulek gratefully acknowledges support from Austrian Science Fund
(FWF), Project M2281-N35. A. Kupavskii was supported by the Advanced Postdoc.Mobility
Grant no. P300P2_177839 of the Swiss National Science Foundation. Research by P.
Valtr was supported by the Grant no. 18-19158 S of the Czech Science Foundation
(GAČR)."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Radoslav
full_name: Fulek, Radoslav
id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
last_name: Fulek
orcid: 0000-0001-8485-1774
- first_name: Bernd
full_name: Gärtner, Bernd
last_name: Gärtner
- first_name: Andrey
full_name: Kupavskii, Andrey
last_name: Kupavskii
- first_name: Pavel
full_name: Valtr, Pavel
last_name: Valtr
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. The crossing Tverberg theorem.
Discrete and Computational Geometry. 2024;72:831-848. doi:10.1007/s00454-023-00532-x
apa: Fulek, R., Gärtner, B., Kupavskii, A., Valtr, P., & Wagner, U. (2024).
The crossing Tverberg theorem. Discrete and Computational Geometry. Springer
Nature. https://doi.org/10.1007/s00454-023-00532-x
chicago: Fulek, Radoslav, Bernd Gärtner, Andrey Kupavskii, Pavel Valtr, and Uli
Wagner. “The Crossing Tverberg Theorem.” Discrete and Computational Geometry.
Springer Nature, 2024. https://doi.org/10.1007/s00454-023-00532-x.
ieee: R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, and U. Wagner, “The crossing
Tverberg theorem,” Discrete and Computational Geometry, vol. 72. Springer
Nature, pp. 831–848, 2024.
ista: Fulek R, Gärtner B, Kupavskii A, Valtr P, Wagner U. 2024. The crossing Tverberg
theorem. Discrete and Computational Geometry. 72, 831–848.
mla: Fulek, Radoslav, et al. “The Crossing Tverberg Theorem.” Discrete and Computational
Geometry, vol. 72, Springer Nature, 2024, pp. 831–48, doi:10.1007/s00454-023-00532-x.
short: R. Fulek, B. Gärtner, A. Kupavskii, P. Valtr, U. Wagner, Discrete and Computational
Geometry 72 (2024) 831–848.
date_created: 2023-08-06T22:01:12Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-04-14T13:52:36Z
day: '01'
department:
- _id: UlWa
doi: 10.1007/s00454-023-00532-x
external_id:
arxiv:
- '1812.04911'
isi:
- '001038546500001'
intvolume: ' 72'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1812.04911
month: '09'
oa: 1
oa_version: Preprint
page: 831-848
project:
- _id: 261FA626-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02281
name: Eliminating intersections in drawings of graphs
publication: Discrete and Computational Geometry
publication_identifier:
eissn:
- 1432-0444
issn:
- 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '6647'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: The crossing Tverberg theorem
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 72
year: '2024'
...
---
_id: '13975'
abstract:
- lang: eng
text: "We consider the spectrum of random Laplacian matrices of the form Ln=An−Dn
where An\r\n is a real symmetric random matrix and Dn is a diagonal matrix whose
entries are equal to the corresponding row sums of An. If An is a Wigner matrix
with entries in the domain of attraction of a Gaussian distribution, the empirical
spectral measure of Ln is known to converge to the free convolution of a semicircle
distribution and a standard real Gaussian distribution. We consider real symmetric
random matrices An with independent entries (up to symmetry) whose row sums converge
to a purely non-Gaussian infinitely divisible distribution, which fall into the
class of Lévy–Khintchine random matrices first introduced by Jung [Trans Am Math
Soc, 370, (2018)]. Our main result shows that the empirical spectral measure of
Ln converges almost surely to a deterministic limit. A key step in the proof
is to use the purely non-Gaussian nature of the row sums to build a random operator
to which Ln converges in an appropriate sense. This operator leads to a recursive
distributional equation uniquely describing the Stieltjes transform of the limiting
empirical spectral measure."
acknowledgement: "The first author thanks Yizhe Zhu for pointing out reference [30].
We thank David Renfrew for comments on an earlier draft. We thank the anonymous
referee for a careful reading and helpful comments.\r\nOpen access funding provided
by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Andrew J
full_name: Campbell, Andrew J
id: 582b06a9-1f1c-11ee-b076-82ffce00dde4
last_name: Campbell
- first_name: Sean
full_name: O’Rourke, Sean
last_name: O’Rourke
citation:
ama: Campbell AJ, O’Rourke S. Spectrum of Lévy–Khintchine random laplacian matrices.
Journal of Theoretical Probability. 2024;37:933-973. doi:10.1007/s10959-023-01275-4
apa: Campbell, A. J., & O’Rourke, S. (2024). Spectrum of Lévy–Khintchine random
laplacian matrices. Journal of Theoretical Probability. Springer Nature.
https://doi.org/10.1007/s10959-023-01275-4
chicago: Campbell, Andrew J, and Sean O’Rourke. “Spectrum of Lévy–Khintchine Random
Laplacian Matrices.” Journal of Theoretical Probability. Springer Nature,
2024. https://doi.org/10.1007/s10959-023-01275-4.
ieee: A. J. Campbell and S. O’Rourke, “Spectrum of Lévy–Khintchine random laplacian
matrices,” Journal of Theoretical Probability, vol. 37. Springer Nature,
pp. 933–973, 2024.
ista: Campbell AJ, O’Rourke S. 2024. Spectrum of Lévy–Khintchine random laplacian
matrices. Journal of Theoretical Probability. 37, 933–973.
mla: Campbell, Andrew J., and Sean O’Rourke. “Spectrum of Lévy–Khintchine Random
Laplacian Matrices.” Journal of Theoretical Probability, vol. 37, Springer
Nature, 2024, pp. 933–73, doi:10.1007/s10959-023-01275-4.
short: A.J. Campbell, S. O’Rourke, Journal of Theoretical Probability 37 (2024)
933–973.
corr_author: '1'
date_created: 2023-08-06T22:01:13Z
date_published: 2024-03-01T00:00:00Z
date_updated: 2024-07-22T09:41:42Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s10959-023-01275-4
external_id:
arxiv:
- '2210.07927'
isi:
- '001038341000001'
file:
- access_level: open_access
checksum: f7793d313104c70422140c5e6494c779
content_type: application/pdf
creator: dernst
date_created: 2024-07-22T09:41:21Z
date_updated: 2024-07-22T09:41:21Z
file_id: '17300'
file_name: 2024_JourTheorProbab_Campbell.pdf
file_size: 555070
relation: main_file
success: 1
file_date_updated: 2024-07-22T09:41:21Z
has_accepted_license: '1'
intvolume: ' 37'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 933-973
publication: Journal of Theoretical Probability
publication_identifier:
eissn:
- 1572-9230
issn:
- 0894-9840
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectrum of Lévy–Khintchine random laplacian matrices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2024'
...
---
_id: '14213'
abstract:
- lang: eng
text: We introduce a method to segment the visual field into independently moving
regions, trained with no ground truth or supervision. It consists of an adversarial
conditional encoder-decoder architecture based on Slot Attention, modified to
use the image as context to decode optical flow without attempting to reconstruct
the image itself. In the resulting multi-modal representation, one modality (flow)
feeds the encoder to produce separate latent codes (slots), whereas the other
modality (image) conditions the decoder to generate the first (flow) from the
slots. This design frees the representation from having to encode complex nuisance
variability in the image due to, for instance, illumination and reflectance properties
of the scene. Since customary autoencoding based on minimizing the reconstruction
error does not preclude the entire flow from being encoded into a single slot,
we modify the loss to an adversarial criterion based on Contextual Information
Separation. The resulting min-max optimization fosters the separation of objects
and their assignment to different attention slots, leading to Divided Attention,
or DivA. DivA outperforms recent unsupervised multi-object motion segmentation
methods while tripling run-time speed up to 104FPS and reducing the performance
gap from supervised methods to 12% or less. DivA can handle different numbers
of objects and different image sizes at training and test time, is invariant to
permutation of object labels, and does not require explicit regularization.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dong
full_name: Lao, Dong
last_name: Lao
- first_name: Zhengyang
full_name: Hu, Zhengyang
last_name: Hu
- first_name: Francesco
full_name: Locatello, Francesco
id: 26cfd52f-2483-11ee-8040-88983bcc06d4
last_name: Locatello
orcid: 0000-0002-4850-0683
- first_name: Yanchao
full_name: Yang, Yanchao
last_name: Yang
- first_name: Stefano
full_name: Soatto, Stefano
last_name: Soatto
citation:
ama: 'Lao D, Hu Z, Locatello F, Yang Y, Soatto S. Divided attention: Unsupervised
multi-object discovery with contextually separated slots. In: 1st Conference
on Parsimony and Learning. ; 2024.'
apa: 'Lao, D., Hu, Z., Locatello, F., Yang, Y., & Soatto, S. (2024). Divided
attention: Unsupervised multi-object discovery with contextually separated slots.
In 1st Conference on Parsimony and Learning. Hong Kong, China.'
chicago: 'Lao, Dong, Zhengyang Hu, Francesco Locatello, Yanchao Yang, and Stefano
Soatto. “Divided Attention: Unsupervised Multi-Object Discovery with Contextually
Separated Slots.” In 1st Conference on Parsimony and Learning, 2024.'
ieee: 'D. Lao, Z. Hu, F. Locatello, Y. Yang, and S. Soatto, “Divided attention:
Unsupervised multi-object discovery with contextually separated slots,” in 1st
Conference on Parsimony and Learning, Hong Kong, China, 2024.'
ista: 'Lao D, Hu Z, Locatello F, Yang Y, Soatto S. 2024. Divided attention: Unsupervised
multi-object discovery with contextually separated slots. 1st Conference on Parsimony
and Learning. CPAL: Conference on Parsimony and Learning.'
mla: 'Lao, Dong, et al. “Divided Attention: Unsupervised Multi-Object Discovery
with Contextually Separated Slots.” 1st Conference on Parsimony and Learning,
2024.'
short: D. Lao, Z. Hu, F. Locatello, Y. Yang, S. Soatto, in:, 1st Conference on Parsimony
and Learning, 2024.
conference:
end_date: 2024-01-03
location: Hong Kong, China
name: 'CPAL: Conference on Parsimony and Learning'
start_date: 2024-01-03
date_created: 2023-08-22T14:19:59Z
date_published: 2024-01-03T00:00:00Z
date_updated: 2024-02-12T08:56:23Z
day: '03'
ddc:
- '000'
department:
- _id: FrLo
external_id:
arxiv:
- '2304.01430'
file:
- access_level: open_access
checksum: 8fad894c34f1b3d5a14fb8ffb12f7277
content_type: application/pdf
creator: dernst
date_created: 2024-02-12T08:40:36Z
date_updated: 2024-02-12T08:40:36Z
file_id: '14978'
file_name: 2024_CPAL_Lao.pdf
file_size: 8038511
relation: main_file
success: 1
file_date_updated: 2024-02-12T08:40:36Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: 1st Conference on Parsimony and Learning
publication_status: published
quality_controlled: '1'
status: public
title: 'Divided attention: Unsupervised multi-object discovery with contextually separated
slots'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '14251'
abstract:
- lang: eng
text: The phytohormone auxin and its directional transport through tissues play
a fundamental role in development of higher plants. This polar auxin transport
predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization
is crucial for development, but its evolution during the rise of morphological
complexity in land plants remains unclear. Here, we performed a cross-species
investigation by observing the trafficking and localization of endogenous and
exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha,
and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion
did not compromise the auxin export function of all examined PINs by using radioactive
auxin export assay and by observing the phenotypic changes in transgenic bryophytes.
Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs
distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root
epidermis, bryophytic PINs show no defined polarity. Pharmacological interference
revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN
polarization. The divergence of PIN polarization and trafficking is also observed
within the bryophyte clade and between tissues of individual species. These results
collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout
land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity
mechanisms.
acknowledgement: This work was supported by the ERC grant (PR1023ERC02) to H. T. and
J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001)
to K. J. L.
article_number: '100669'
article_processing_charge: Yes
article_type: original
author:
- first_name: Han
full_name: Tang, Han
id: 19BDF720-25A0-11EA-AC6E-928F3DDC885E
last_name: Tang
orcid: 0000-0001-6152-6637
- first_name: KJ
full_name: Lu, KJ
last_name: Lu
- first_name: Y
full_name: Zhang, Y
last_name: Zhang
- first_name: YL
full_name: Cheng, YL
last_name: Cheng
- first_name: SL
full_name: Tu, SL
last_name: Tu
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and
polarization mechanisms for PIN auxin transporters during land plant evolution.
Plant Communications. 2024;5(1). doi:10.1016/j.xplc.2023.100669
apa: Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., & Friml, J. (2024). Divergence
of trafficking and polarization mechanisms for PIN auxin transporters during land
plant evolution. Plant Communications. Elsevier. https://doi.org/10.1016/j.xplc.2023.100669
chicago: Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence
of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land
Plant Evolution.” Plant Communications. Elsevier, 2024. https://doi.org/10.1016/j.xplc.2023.100669.
ieee: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking
and polarization mechanisms for PIN auxin transporters during land plant evolution,”
Plant Communications, vol. 5, no. 1. Elsevier, 2024.
ista: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking
and polarization mechanisms for PIN auxin transporters during land plant evolution.
Plant Communications. 5(1), 100669.
mla: Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for
PIN Auxin Transporters during Land Plant Evolution.” Plant Communications,
vol. 5, no. 1, 100669, Elsevier, 2024, doi:10.1016/j.xplc.2023.100669.
short: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications
5 (2024).
corr_author: '1'
date_created: 2023-09-01T11:32:02Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2025-08-05T13:27:26Z
day: '08'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.xplc.2023.100669
ec_funded: 1
external_id:
isi:
- '001158054500001'
pmid:
- '37528584'
file:
- access_level: open_access
checksum: edbc44c6d4a394d2bf70f92fdbb08f0a
content_type: application/pdf
creator: dernst
date_created: 2024-01-30T12:59:57Z
date_updated: 2024-01-30T12:59:57Z
file_id: '14911'
file_name: 2023_PlantCommunications_Tang.pdf
file_size: 2825565
relation: main_file
success: 1
file_date_updated: 2024-01-30T12:59:57Z
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Plant Communications
publication_identifier:
issn:
- 2590-3462
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Divergence of trafficking and polarization mechanisms for PIN auxin transporters
during land plant evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14257'
abstract:
- lang: eng
text: Mapping the complex and dense arrangement of cells and their connectivity
in brain tissue demands nanoscale spatial resolution imaging. Super-resolution
optical microscopy excels at visualizing specific molecules and individual cells
but fails to provide tissue context. Here we developed Comprehensive Analysis
of Tissues across Scales (CATS), a technology to densely map brain tissue architecture
from millimeter regional to nanometer synaptic scales in diverse chemically fixed
brain preparations, including rodent and human. CATS uses fixation-compatible
extracellular labeling and optical imaging, including stimulated emission depletion
or expansion microscopy, to comprehensively delineate cellular structures. It
enables three-dimensional reconstruction of single synapses and mapping of synaptic
connectivity by identification and analysis of putative synaptic cleft regions.
Applying CATS to the mouse hippocampal mossy fiber circuitry, we reconstructed
and quantified the synaptic input and output structure of identified neurons.
We furthermore demonstrate applicability to clinically derived human tissue samples,
including formalin-fixed paraffin-embedded routine diagnostic specimens, for visualizing
the cellular architecture of brain tissue in health and disease.
acknowledged_ssus:
- _id: ScienComp
- _id: Bio
- _id: PreCl
- _id: LifeSc
- _id: M-Shop
- _id: E-Lib
acknowledgement: 'We thank J. Vorlaufer, N. Agudelo-Dueñas, W. Jahr and A. Wartak
for microscope maintenance and troubleshooting; C. Kreuzinger, A. Freeman and I.
Erber for technical assistance; and M. Tomschik for support with obtaining human
samples. We gratefully acknowledge E. Miguel for setting up webKnossos and M. Šuplata
for computational support and hardware control. We are grateful to R. Shigemoto
and B. Bickel for generous support and M. Sixt and S. Boyd (Stanford University)
for discussions and critical reading of the paper. PSD95-HaloTag mice were kindly
provided by S. Grant (University of Edinburgh). We acknowledge expert support by
Institute of Science and Technology Austria’s scientific computing, imaging and
optics, preclinical and lab support facilities and by the Miba machine shop and
library. We gratefully acknowledge funding by the following sources: Austrian Science
Fund (FWF) grant I3600-B27 (J.G.D.); Austrian Science Fund (FWF) grant DK W1232
(J.G.D. and J.M.M.); Austrian Science Fund (FWF) grant Z 312-B27, Wittgenstein award
(P.J.); Austrian Science Fund (FWF) projects I4685-B, I6565-B (SYNABS) and DOC 33-B27
(R.H.); Gesellschaft für Forschungsförderung NÖ (NFB) grant LSC18-022 (J.G.D.);
European Union’s Horizon 2020 research and innovation programme, European Research
Council (ERC) grant 715508 – REVERSEAUTISM (G.N.); European Union’s Horizon 2020
research and innovation programme, European Research Council (ERC) grant 692692
– GIANTSYN (P.J.); Marie Skłodowska-Curie Actions Fellowship GA no. 665385 under
the EU Horizon 2020 program (J.M.M. and J.L.); and Marie Skłodowska-Curie Actions
Individual Fellowship no. 101026635 under the EU Horizon 2020 program (J.F.W.).'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Julia M
full_name: Michalska, Julia M
id: 443DB6DE-F248-11E8-B48F-1D18A9856A87
last_name: Michalska
orcid: 0000-0003-3862-1235
- first_name: Julia
full_name: Lyudchik, Julia
id: 46E28B80-F248-11E8-B48F-1D18A9856A87
last_name: Lyudchik
- first_name: Philipp
full_name: Velicky, Philipp
id: 39BDC62C-F248-11E8-B48F-1D18A9856A87
last_name: Velicky
orcid: 0000-0002-2340-7431
- first_name: Hana
full_name: Korinkova, Hana
id: ee3cb6ca-ec98-11ea-ae11-ff703e2254ed
last_name: Korinkova
- first_name: Jake
full_name: Watson, Jake
id: 63836096-4690-11EA-BD4E-32803DDC885E
last_name: Watson
orcid: 0000-0002-8698-3823
- first_name: Alban
full_name: Cenameri, Alban
id: 9ac8f577-2357-11eb-997a-e566c5550886
last_name: Cenameri
- first_name: Christoph M
full_name: Sommer, Christoph M
id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
last_name: Sommer
orcid: 0000-0003-1216-9105
- first_name: Nicole
full_name: Amberg, Nicole
id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
last_name: Amberg
orcid: 0000-0002-3183-8207
- first_name: Alessandro
full_name: Venturino, Alessandro
id: 41CB84B2-F248-11E8-B48F-1D18A9856A87
last_name: Venturino
orcid: 0000-0003-2356-9403
- first_name: Karl
full_name: Roessler, Karl
last_name: Roessler
- first_name: Thomas
full_name: Czech, Thomas
last_name: Czech
- first_name: Romana
full_name: Höftberger, Romana
last_name: Höftberger
- first_name: Sandra
full_name: Siegert, Sandra
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
citation:
ama: Michalska JM, Lyudchik J, Velicky P, et al. Imaging brain tissue architecture
across millimeter to nanometer scales. Nature Biotechnology. 2024;42:1051-1064.
doi:10.1038/s41587-023-01911-8
apa: Michalska, J. M., Lyudchik, J., Velicky, P., Korinkova, H., Watson, J., Cenameri,
A., … Danzl, J. G. (2024). Imaging brain tissue architecture across millimeter
to nanometer scales. Nature Biotechnology. Springer Nature. https://doi.org/10.1038/s41587-023-01911-8
chicago: Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake
Watson, Alban Cenameri, Christoph M Sommer, et al. “Imaging Brain Tissue Architecture
across Millimeter to Nanometer Scales.” Nature Biotechnology. Springer
Nature, 2024. https://doi.org/10.1038/s41587-023-01911-8.
ieee: J. M. Michalska et al., “Imaging brain tissue architecture across millimeter
to nanometer scales,” Nature Biotechnology, vol. 42. Springer Nature, pp.
1051–1064, 2024.
ista: Michalska JM, Lyudchik J, Velicky P, Korinkova H, Watson J, Cenameri A, Sommer
CM, Amberg N, Venturino A, Roessler K, Czech T, Höftberger R, Siegert S, Novarino
G, Jonas PM, Danzl JG. 2024. Imaging brain tissue architecture across millimeter
to nanometer scales. Nature Biotechnology. 42, 1051–1064.
mla: Michalska, Julia M., et al. “Imaging Brain Tissue Architecture across Millimeter
to Nanometer Scales.” Nature Biotechnology, vol. 42, Springer Nature, 2024,
pp. 1051–64, doi:10.1038/s41587-023-01911-8.
short: J.M. Michalska, J. Lyudchik, P. Velicky, H. Korinkova, J. Watson, A. Cenameri,
C.M. Sommer, N. Amberg, A. Venturino, K. Roessler, T. Czech, R. Höftberger, S.
Siegert, G. Novarino, P.M. Jonas, J.G. Danzl, Nature Biotechnology 42 (2024) 1051–1064.
corr_author: '1'
date_created: 2023-09-03T22:01:15Z
date_published: 2024-07-01T00:00:00Z
date_updated: 2026-04-14T08:34:35Z
day: '01'
ddc:
- '570'
department:
- _id: SaSi
- _id: GaNo
- _id: PeJo
- _id: JoDa
- _id: Bio
- _id: RySh
doi: 10.1038/s41587-023-01911-8
ec_funded: 1
external_id:
isi:
- '001065254200001'
pmid:
- '37653226'
file:
- access_level: open_access
checksum: 57d5fafb16f02dcb9f7dddb1bd7e2a71
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T07:48:01Z
date_updated: 2025-01-09T07:48:01Z
file_id: '18784'
file_name: 2024_NatureBiotech_Michalska.pdf
file_size: 26065165
relation: main_file
success: 1
file_date_updated: 2025-01-09T07:48:01Z
has_accepted_license: '1'
intvolume: ' 42'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1051-1064
pmid: 1
project:
- _id: 265CB4D0-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03600
name: Optical control of synaptic function via adhesion molecules
- _id: 2548AE96-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: W1232
name: Molecular Drug Targets
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00312
name: Synaptic communication in neuronal microcircuits
- _id: 23889792-32DE-11EA-91FC-C7463DDC885E
grant_number: LS18-022
name: High content imaging to decode human immune cell interactions in health and
allergic disease
- _id: 25444568-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715508'
name: Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo
and in vitro Models
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '692692'
name: Biophysics and circuit function of a giant cortical glutamatergic synapse
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
- _id: fc2be41b-9c52-11eb-aca3-faa90aa144e9
call_identifier: H2020
grant_number: '101026635'
name: Synaptic computations of the hippocampal CA3 circuitry
publication: Nature Biotechnology
publication_identifier:
eissn:
- 1546-1696
issn:
- 1087-0156
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/danzllab/CATS
record:
- id: '18660'
relation: dissertation_contains
status: deleted
- id: '13126'
relation: research_data
status: public
- id: '18674'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Imaging brain tissue architecture across millimeter to nanometer scales
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2024'
...
---
_id: '14345'
abstract:
- lang: eng
text: For a locally finite set in R2, the order-k Brillouin tessellations form an
infinite sequence of convex face-to-face tilings of the plane. If the set is coarsely
dense and generic, then the corresponding infinite sequences of minimum and maximum
angles are both monotonic in k. As an example, a stationary Poisson point process
in R2 is locally finite, coarsely dense, and generic with probability one. For
such a set, the distributions of angles in the Voronoi tessellations, Delaunay
mosaics, and Brillouin tessellations are independent of the order and can be derived
from the formula for angles in order-1 Delaunay mosaics given by Miles (Math.
Biosci. 6, 85–127 (1970)).
acknowledgement: Work by all authors but A. Garber is supported by the European Research
Council (ERC), Grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund
(FWF), Grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109,
Austrian Science Fund (FWF), Grant No. I 02979-N35. Work by A. Garber is partially
supported by the Alexander von Humboldt Foundation.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Alexey
full_name: Garber, Alexey
last_name: Garber
- first_name: Mohadese
full_name: Ghafari, Mohadese
last_name: Ghafari
- first_name: Teresa
full_name: Heiss, Teresa
id: 4879BB4E-F248-11E8-B48F-1D18A9856A87
last_name: Heiss
orcid: 0000-0002-1780-2689
- first_name: Morteza
full_name: Saghafian, Morteza
id: f86f7148-b140-11ec-9577-95435b8df824
last_name: Saghafian
citation:
ama: Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. On angles in higher
order Brillouin tessellations and related tilings in the plane. Discrete and
Computational Geometry. 2024;72:29-48. doi:10.1007/s00454-023-00566-1
apa: Edelsbrunner, H., Garber, A., Ghafari, M., Heiss, T., & Saghafian, M. (2024).
On angles in higher order Brillouin tessellations and related tilings in the plane.
Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-023-00566-1
chicago: Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafari, Teresa Heiss, and
Morteza Saghafian. “On Angles in Higher Order Brillouin Tessellations and Related
Tilings in the Plane.” Discrete and Computational Geometry. Springer Nature,
2024. https://doi.org/10.1007/s00454-023-00566-1.
ieee: H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, and M. Saghafian, “On angles
in higher order Brillouin tessellations and related tilings in the plane,” Discrete
and Computational Geometry, vol. 72. Springer Nature, pp. 29–48, 2024.
ista: Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. 2024. On angles
in higher order Brillouin tessellations and related tilings in the plane. Discrete
and Computational Geometry. 72, 29–48.
mla: Edelsbrunner, Herbert, et al. “On Angles in Higher Order Brillouin Tessellations
and Related Tilings in the Plane.” Discrete and Computational Geometry,
vol. 72, Springer Nature, 2024, pp. 29–48, doi:10.1007/s00454-023-00566-1.
short: H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, M. Saghafian, Discrete
and Computational Geometry 72 (2024) 29–48.
corr_author: '1'
date_created: 2023-09-17T22:01:10Z
date_published: 2024-07-01T00:00:00Z
date_updated: 2025-04-23T08:41:59Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00454-023-00566-1
ec_funded: 1
external_id:
arxiv:
- '2204.01076'
isi:
- '001060727600004'
pmid:
- '39610762'
file:
- access_level: open_access
checksum: b207b4e00f904e8ea8a30e24f0251f79
content_type: application/pdf
creator: dernst
date_created: 2024-07-22T09:43:19Z
date_updated: 2024-07-22T09:43:19Z
file_id: '17301'
file_name: 2024_DiscreteComputGeom_Edelsbrunner.pdf
file_size: 892019
relation: main_file
success: 1
file_date_updated: 2024-07-22T09:43:19Z
has_accepted_license: '1'
intvolume: ' 72'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 29-48
pmid: 1
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
publication: Discrete and Computational Geometry
publication_identifier:
eissn:
- 1432-0444
issn:
- 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On angles in higher order Brillouin tessellations and related tilings in the
plane
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 72
year: '2024'
...
---
_id: '14400'
abstract:
- lang: eng
text: "We consider the problem of computing the maximal probability of satisfying
an \r\n-regular specification for stochastic, continuous-state, nonlinear systems
evolving in discrete time. The problem reduces, after automata-theoretic constructions,
to finding the maximal probability of satisfying a parity condition on a (possibly
hybrid) state space. While characterizing the exact satisfaction probability is
open, we show that a lower bound on this probability can be obtained by (I) computing
an under-approximation of the qualitative winning region, i.e., states from which
the parity condition can be enforced almost surely, and (II) computing the maximal
probability of reaching this qualitative winning region.\r\nThe heart of our approach
is a technique to symbolically compute the under-approximation of the qualitative
winning region in step (I) via a finite-state abstraction of the original system
as a \r\n-player parity game. Our abstraction procedure uses only the support
of the probabilistic evolution; it does not use precise numerical transition probabilities.
We prove that the winning set in the abstract -player game induces an under-approximation
of the qualitative winning region in the original synthesis problem, along with
a policy to solve it. By combining these contributions with (a) a symbolic fixpoint
algorithm to solve \r\n-player games and (b) existing techniques for reachability
policy synthesis in stochastic nonlinear systems, we get an abstraction-based
algorithm for finding a lower bound on the maximal satisfaction probability.\r\nWe
have implemented the abstraction-based algorithm in Mascot-SDS, where we combined
the outlined abstraction step with our tool Genie (Majumdar et al., 2023) that
solves \r\n-player parity games (through a reduction to Rabin games) more efficiently
than existing algorithms. We evaluated our implementation on the nonlinear model
of a perturbed bistable switch from the literature. We show empirically that the
lower bound on the winning region computed by our approach is precise, by comparing
against an over-approximation of the qualitative winning region. Moreover, our
implementation outperforms a recently proposed tool for solving this problem by
a large margin."
acknowledgement: "We thank Daniel Hausmann and Nir Piterman for their valuable comments
on an earlier version of the manuscript of our other paper [22] where we present,
among other things, the parity fixpoint for 2 1/2-player games (for a slightly more
general class of games) with a different and indirect proof of correctness. Based
on their comments we observed that, unlike the other fixpoints that we present in
[22], the parity fixpoint does not follow the exact same structure as its counterpart
for 2-player games, which we also use int his paper.\r\nWe also thank Thejaswini
Raghavan for observing that our symbolic parity fixpoint algorithm can be solved
in quasi-polynomial time using recent improved algorithms for solving \r\n-calculus
expressions. This significantly improved the complexity bounds of our algorithm
in this paper.\r\nThe work of R. Majumdar and A.-K. Schmuck are partially supported
by DFG, Germany project 389792660 TRR 248–CPEC. A.-K. Schmuck is additionally funded
through DFG, Germany project (SCHM 3541/1-1). K. Mallik is supported by the ERC
project ERC-2020-AdG 101020093. S. Soudjani is supported by the following projects:
EPSRC EP/V043676/1, EIC 101070802, and ERC 101089047."
article_number: '101430'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Rupak
full_name: Majumdar, Rupak
last_name: Majumdar
- first_name: Kaushik
full_name: Mallik, Kaushik
id: 0834ff3c-6d72-11ec-94e0-b5b0a4fb8598
last_name: Mallik
orcid: 0000-0001-9864-7475
- first_name: Anne Kathrin
full_name: Schmuck, Anne Kathrin
last_name: Schmuck
- first_name: Sadegh
full_name: Soudjani, Sadegh
last_name: Soudjani
citation:
ama: 'Majumdar R, Mallik K, Schmuck AK, Soudjani S. Symbolic control for stochastic
systems via finite parity games. Nonlinear Analysis: Hybrid Systems. 2024;51(2).
doi:10.1016/j.nahs.2023.101430'
apa: 'Majumdar, R., Mallik, K., Schmuck, A. K., & Soudjani, S. (2024). Symbolic
control for stochastic systems via finite parity games. Nonlinear Analysis:
Hybrid Systems. Elsevier. https://doi.org/10.1016/j.nahs.2023.101430'
chicago: 'Majumdar, Rupak, Kaushik Mallik, Anne Kathrin Schmuck, and Sadegh Soudjani.
“Symbolic Control for Stochastic Systems via Finite Parity Games.” Nonlinear
Analysis: Hybrid Systems. Elsevier, 2024. https://doi.org/10.1016/j.nahs.2023.101430.'
ieee: 'R. Majumdar, K. Mallik, A. K. Schmuck, and S. Soudjani, “Symbolic control
for stochastic systems via finite parity games,” Nonlinear Analysis: Hybrid
Systems, vol. 51, no. 2. Elsevier, 2024.'
ista: 'Majumdar R, Mallik K, Schmuck AK, Soudjani S. 2024. Symbolic control for
stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems.
51(2), 101430.'
mla: 'Majumdar, Rupak, et al. “Symbolic Control for Stochastic Systems via Finite
Parity Games.” Nonlinear Analysis: Hybrid Systems, vol. 51, no. 2, 101430,
Elsevier, 2024, doi:10.1016/j.nahs.2023.101430.'
short: 'R. Majumdar, K. Mallik, A.K. Schmuck, S. Soudjani, Nonlinear Analysis: Hybrid
Systems 51 (2024).'
corr_author: '1'
date_created: 2023-10-08T22:01:15Z
date_published: 2024-02-01T00:00:00Z
date_updated: 2025-04-14T07:55:55Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1016/j.nahs.2023.101430
ec_funded: 1
external_id:
arxiv:
- '2101.00834'
isi:
- '001093188100001'
file:
- access_level: open_access
checksum: 4eab70274d1004ea411f7f0e74c033ac
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T10:26:41Z
date_updated: 2024-07-16T10:26:41Z
file_id: '17258'
file_name: 2024_NonlinearAnalysis_Majumdar.pdf
file_size: 1787569
relation: main_file
success: 1
file_date_updated: 2024-07-16T10:26:41Z
has_accepted_license: '1'
intvolume: ' 51'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
call_identifier: H2020
grant_number: '101020093'
name: Vigilant Algorithmic Monitoring of Software
publication: 'Nonlinear Analysis: Hybrid Systems'
publication_identifier:
issn:
- 1751-570X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Symbolic control for stochastic systems via finite parity games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 51
year: '2024'
...
---
_id: '14408'
abstract:
- lang: eng
text: "We prove that the mesoscopic linear statistics ∑if(na(σi−z0)) of the eigenvalues
{σi}i of large n×n non-Hermitian random matrices with complex centred i.i.d. entries
are asymptotically Gaussian for any H20-functions f around any point z0 in the
bulk of the spectrum on any mesoscopic scale 0Probability Theory and Related Fields. 2024;188:1131-1182.
doi:10.1007/s00440-023-01229-1
apa: Cipolloni, G., Erdös, L., & Schröder, D. J. (2024). Mesoscopic central
limit theorem for non-Hermitian random matrices. Probability Theory and Related
Fields. Springer Nature. https://doi.org/10.1007/s00440-023-01229-1
chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Mesoscopic Central
Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related
Fields. Springer Nature, 2024. https://doi.org/10.1007/s00440-023-01229-1.
ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Mesoscopic central limit theorem
for non-Hermitian random matrices,” Probability Theory and Related Fields,
vol. 188. Springer Nature, pp. 1131–1182, 2024.
ista: Cipolloni G, Erdös L, Schröder DJ. 2024. Mesoscopic central limit theorem
for non-Hermitian random matrices. Probability Theory and Related Fields. 188,
1131–1182.
mla: Cipolloni, Giorgio, et al. “Mesoscopic Central Limit Theorem for Non-Hermitian
Random Matrices.” Probability Theory and Related Fields, vol. 188, Springer
Nature, 2024, pp. 1131–82, doi:10.1007/s00440-023-01229-1.
short: G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields
188 (2024) 1131–1182.
date_created: 2023-10-08T22:01:17Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-08-05T13:28:15Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s00440-023-01229-1
ec_funded: 1
external_id:
arxiv:
- '2210.12060'
isi:
- '001118972500001'
intvolume: ' 188'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2210.12060
month: '04'
oa: 1
oa_version: Preprint
page: 1131-1182
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
call_identifier: H2020
grant_number: '101020331'
name: Random matrices beyond Wigner-Dyson-Mehta
publication: Probability Theory and Related Fields
publication_identifier:
eissn:
- 1432-2064
issn:
- 0178-8051
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mesoscopic central limit theorem for non-Hermitian random matrices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 188
year: '2024'
...
---
_id: '14435'
abstract:
- lang: eng
text: Low‐cost, safe, and environmental‐friendly rechargeable aqueous zinc‐ion batteries
(ZIBs) are promising as next‐generation energy storage devices for wearable electronics
among other applications. However, sluggish ionic transport kinetics and the unstable
electrode structure during ionic insertion/extraction hampers their deployment.
Herein, we propose a new cathode material based on a layered metal chalcogenide
(LMC), bismuth telluride (Bi2Te3), coated
with polypyrrole (PPy). Taking advantage of the PPy coating, the Bi2Te3@PPy
composite presents strong ionic absorption affinity, high oxidation resistance,
and high structural stability. The ZIBs based on Bi2Te3@PPy
cathodes exhibit high capacities and ultra‐long lifespans of over 5000 cycles.
They also present outstanding stability even under bending. In addition, we analyze
here the reaction mechanism using in situ X‐ray diffraction, X‐ray photoelectron
spectroscopy, and computational tools and demonstrate that, in the aqueous system,
Zn2+ is not inserted into the cathode as previously assumed.
In contrast, proton charge storage dominates the process. Overall, this work not
only shows the great potential of LMCs as ZIBs cathode materials and the advantages
of PPy coating, but also clarifies the charge/discharge mechanism in rechargeable
ZIBs based on LMCs.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: G.Z. and Q.S. contributed equally to this work. This work was supported
by the National Natural Science Foundation of China (52105329, 52175300) and the
Heilongjiang Provincial Natural Science Foundation of China (LH2022E059). G.Z.,
X.L., and C.Z. thank the China Scholarship Council (CSC) for the scholarship support.
This research was supported by the Scientific Service Units of ISTA through resources
provided by the Electron Microscopy Facility. S.H. and M.I. acknowledge funding
by ISTA and Werner Siemens.
article_number: '2305128'
article_processing_charge: No
article_type: original
author:
- first_name: Guifang
full_name: Zeng, Guifang
last_name: Zeng
- first_name: Qing
full_name: Sun, Qing
last_name: Sun
- first_name: Sharona
full_name: Horta, Sharona
id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc
last_name: Horta
- first_name: Shang
full_name: Wang, Shang
last_name: Wang
- first_name: Xuan
full_name: Lu, Xuan
last_name: Lu
- first_name: Chaoyue
full_name: Zhang, Chaoyue
last_name: Zhang
- first_name: Jing
full_name: Li, Jing
last_name: Li
- first_name: Junshan
full_name: Li, Junshan
last_name: Li
- first_name: Lijie
full_name: Ci, Lijie
last_name: Ci
- first_name: Yanhong
full_name: Tian, Yanhong
last_name: Tian
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: 'Zeng G, Sun Q, Horta S, et al. A layered Bi2Te3@PPy cathode for aqueous zinc
ion batteries: Mechanism and application in printed flexible batteries. Advanced
Materials. 2024;36(1). doi:10.1002/adma.202305128'
apa: 'Zeng, G., Sun, Q., Horta, S., Wang, S., Lu, X., Zhang, C., … Cabot, A. (2024).
A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application
in printed flexible batteries. Advanced Materials. Wiley. https://doi.org/10.1002/adma.202305128'
chicago: 'Zeng, Guifang, Qing Sun, Sharona Horta, Shang Wang, Xuan Lu, Chaoyue Zhang,
Jing Li, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries:
Mechanism and Application in Printed Flexible Batteries.” Advanced Materials.
Wiley, 2024. https://doi.org/10.1002/adma.202305128.'
ieee: 'G. Zeng et al., “A layered Bi2Te3@PPy cathode for aqueous zinc ion
batteries: Mechanism and application in printed flexible batteries,” Advanced
Materials, vol. 36, no. 1. Wiley, 2024.'
ista: 'Zeng G, Sun Q, Horta S, Wang S, Lu X, Zhang C, Li J, Li J, Ci L, Tian Y,
Ibáñez M, Cabot A. 2024. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries:
Mechanism and application in printed flexible batteries. Advanced Materials. 36(1),
2305128.'
mla: 'Zeng, Guifang, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries:
Mechanism and Application in Printed Flexible Batteries.” Advanced Materials,
vol. 36, no. 1, 2305128, Wiley, 2024, doi:10.1002/adma.202305128.'
short: G. Zeng, Q. Sun, S. Horta, S. Wang, X. Lu, C. Zhang, J. Li, J. Li, L. Ci,
Y. Tian, M. Ibáñez, A. Cabot, Advanced Materials 36 (2024).
date_created: 2023-10-17T10:53:56Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-04-15T06:36:40Z
day: '04'
department:
- _id: MaIb
doi: 10.1002/adma.202305128
external_id:
isi:
- '001085681000001'
pmid:
- '37555532'
intvolume: ' 36'
isi: 1
issue: '1'
keyword:
- Mechanical Engineering
- Mechanics of Materials
- General Materials Science
language:
- iso: eng
month: '01'
oa_version: None
pmid: 1
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Advanced Materials
publication_identifier:
eissn:
- 1521-4095
issn:
- 0935-9648
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and
application in printed flexible batteries'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2024'
...
---
_id: '14447'
abstract:
- lang: eng
text: "Auxin belongs among major phytohormones and governs multiple aspects of plant
growth and development. The establishment of auxin concentration gradients, determines,
among other processes, plant organ positioning and growth responses to environmental
stimuli.\r\nHerein we report the synthesis of new NBD- or DNS-labelled IAA derivatives
and the elucidation of their biological activity, fluorescence properties and
subcellular accumulation patterns in planta. These novel compounds did not show
auxin-like activity, but instead antagonized physiological auxin effects. The
DNS-labelled derivatives FL5 and FL6 showed strong anti-auxin activity in roots
and hypocotyls, which also occurred at the level of gene transcription as confirmed
by quantitative PCR analysis. The auxin antagonism of our derivatives was further
demonstrated in vitro using an SPR-based binding assay. The NBD-labelled compound
FL4 with the best fluorescence properties proved to be unsuitable to study auxin
accumulation patterns in planta. On the other hand, the strongest anti-auxin activity
possessing compounds FL5 and FL6 could be useful to study binding mechanisms to
auxin receptors and for manipulations of auxin-regulated processes."
acknowledgement: The authors would like to thank Karolína Kubiasová and Iñigo Saiz-Fernández
for valuable scientific discussions. Open access publishing supported by the National
Technical Library in Prague. This work was supported by the Palacký University Olomouc
Young Researcher Grant Competition (JG_2020_002), by the Internal Grant Agency of
Palacký University Olomouc (IGA_PrF_2023_016, IGA_PrF_2023_031), by the Ministry
of Education, Youth and Sports of the Czech Republic through the European Regional
Development Fund-Project Plants as a tool for sustainable global development (CZ.02.1.01/0.0/0.0/16_019/0000827)
and the project Support of mobility at Palacký University Olomouc II. (CZ.02.2.69/0.0/0.0/18_053/0016919).
The Biacore T200 SPR instrument was provided by the WISB Research Technology Facility
within the School of Life Sciences, University of Warwick.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Kristýna
full_name: Bieleszová, Kristýna
last_name: Bieleszová
- first_name: Pavel
full_name: Hladík, Pavel
last_name: Hladík
- first_name: Martin
full_name: Kubala, Martin
last_name: Kubala
- first_name: Richard
full_name: Napier, Richard
last_name: Napier
- first_name: Federica
full_name: Brunoni, Federica
last_name: Brunoni
- first_name: Zuzana
full_name: Gelová, Zuzana
id: 0AE74790-0E0B-11E9-ABC7-1ACFE5697425
last_name: Gelová
orcid: 0000-0003-4783-1752
- first_name: Lukas
full_name: Fiedler, Lukas
id: 7c417475-8972-11ed-ae7b-8b674ca26986
last_name: Fiedler
- first_name: Ivan
full_name: Kulich, Ivan
id: 57a1567c-8314-11eb-9063-c9ddc3451a54
last_name: Kulich
- first_name: Miroslav
full_name: Strnad, Miroslav
last_name: Strnad
- first_name: Karel
full_name: Doležal, Karel
last_name: Doležal
- first_name: Ondřej
full_name: Novák, Ondřej
last_name: Novák
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Asta
full_name: Žukauskaitė, Asta
last_name: Žukauskaitė
citation:
ama: 'Bieleszová K, Hladík P, Kubala M, et al. New fluorescent auxin derivatives:
Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant
Growth Regulation. 2024;102:589-602. doi:10.1007/s10725-023-01083-0'
apa: 'Bieleszová, K., Hladík, P., Kubala, M., Napier, R., Brunoni, F., Gelová, Z.,
… Žukauskaitė, A. (2024). New fluorescent auxin derivatives: Anti-auxin activity
and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation.
Springer Nature. https://doi.org/10.1007/s10725-023-01083-0'
chicago: 'Bieleszová, Kristýna, Pavel Hladík, Martin Kubala, Richard Napier, Federica
Brunoni, Zuzana Gelová, Lukas Fiedler, et al. “New Fluorescent Auxin Derivatives:
Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant
Growth Regulation. Springer Nature, 2024. https://doi.org/10.1007/s10725-023-01083-0.'
ieee: 'K. Bieleszová et al., “New fluorescent auxin derivatives: Anti-auxin
activity and accumulation patterns in Arabidopsis thaliana,” Plant Growth Regulation,
vol. 102. Springer Nature, pp. 589–602, 2024.'
ista: 'Bieleszová K, Hladík P, Kubala M, Napier R, Brunoni F, Gelová Z, Fiedler
L, Kulich I, Strnad M, Doležal K, Novák O, Friml J, Žukauskaitė A. 2024. New fluorescent
auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis
thaliana. Plant Growth Regulation. 102, 589–602.'
mla: 'Bieleszová, Kristýna, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin
Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation,
vol. 102, Springer Nature, 2024, pp. 589–602, doi:10.1007/s10725-023-01083-0.'
short: K. Bieleszová, P. Hladík, M. Kubala, R. Napier, F. Brunoni, Z. Gelová, L.
Fiedler, I. Kulich, M. Strnad, K. Doležal, O. Novák, J. Friml, A. Žukauskaitė,
Plant Growth Regulation 102 (2024) 589–602.
date_created: 2023-10-22T22:01:15Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2024-07-16T08:13:39Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1007/s10725-023-01083-0
external_id:
isi:
- '001084334300001'
file:
- access_level: open_access
checksum: e63271b1d57c1f03c1d993fd62cba59c
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T08:13:24Z
date_updated: 2024-07-16T08:13:24Z
file_id: '17252'
file_name: 2024_PlantGrowthReg_Bieleszova.pdf
file_size: 2847929
relation: main_file
success: 1
file_date_updated: 2024-07-16T08:13:24Z
has_accepted_license: '1'
intvolume: ' 102'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 589-602
publication: Plant Growth Regulation
publication_identifier:
eissn:
- 1573-5087
issn:
- 0167-6903
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns
in Arabidopsis thaliana'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 102
year: '2024'
...
---
_id: '14451'
abstract:
- lang: eng
text: 'We investigate the potential of Multi-Objective, Deep Reinforcement Learning
for stock and cryptocurrency single-asset trading: in particular, we consider
a Multi-Objective algorithm which generalizes the reward functions and discount
factor (i.e., these components are not specified a priori, but incorporated in
the learning process). Firstly, using several important assets (BTCUSD, ETHUSDT,
XRPUSDT, AAPL, SPY, NIFTY50), we verify the reward generalization property of
the proposed Multi-Objective algorithm, and provide preliminary statistical evidence
showing increased predictive stability over the corresponding Single-Objective
strategy. Secondly, we show that the Multi-Objective algorithm has a clear edge
over the corresponding Single-Objective strategy when the reward mechanism is
sparse (i.e., when non-null feedback is infrequent over time). Finally, we discuss
the generalization properties with respect to the discount factor. The entirety
of our code is provided in open-source format.'
acknowledgement: Open access funding provided by Università degli Studi di Trieste
within the CRUI-CARE Agreement. Funding was provided by Austrian Science Fund (Grant
No. F65), Horizon 2020 (Grant No. 754411) and Österreichische Forschungsförderungsgesellschaft.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Federico
full_name: Cornalba, Federico
id: 2CEB641C-A400-11E9-A717-D712E6697425
last_name: Cornalba
orcid: 0000-0002-6269-5149
- first_name: Constantin
full_name: Disselkamp, Constantin
last_name: Disselkamp
- first_name: Davide
full_name: Scassola, Davide
last_name: Scassola
- first_name: Christopher
full_name: Helf, Christopher
last_name: Helf
citation:
ama: 'Cornalba F, Disselkamp C, Scassola D, Helf C. Multi-objective reward generalization:
Improving performance of Deep Reinforcement Learning for applications in single-asset
trading. Neural Computing and Applications. 2024;36(2):617-637. doi:10.1007/s00521-023-09033-7'
apa: 'Cornalba, F., Disselkamp, C., Scassola, D., & Helf, C. (2024). Multi-objective
reward generalization: Improving performance of Deep Reinforcement Learning for
applications in single-asset trading. Neural Computing and Applications.
Springer Nature. https://doi.org/10.1007/s00521-023-09033-7'
chicago: 'Cornalba, Federico, Constantin Disselkamp, Davide Scassola, and Christopher
Helf. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement
Learning for Applications in Single-Asset Trading.” Neural Computing and Applications.
Springer Nature, 2024. https://doi.org/10.1007/s00521-023-09033-7.'
ieee: 'F. Cornalba, C. Disselkamp, D. Scassola, and C. Helf, “Multi-objective reward
generalization: Improving performance of Deep Reinforcement Learning for applications
in single-asset trading,” Neural Computing and Applications, vol. 36, no.
2. Springer Nature, pp. 617–637, 2024.'
ista: 'Cornalba F, Disselkamp C, Scassola D, Helf C. 2024. Multi-objective reward
generalization: Improving performance of Deep Reinforcement Learning for applications
in single-asset trading. Neural Computing and Applications. 36(2), 617–637.'
mla: 'Cornalba, Federico, et al. “Multi-Objective Reward Generalization: Improving
Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.”
Neural Computing and Applications, vol. 36, no. 2, Springer Nature, 2024,
pp. 617–37, doi:10.1007/s00521-023-09033-7.'
short: F. Cornalba, C. Disselkamp, D. Scassola, C. Helf, Neural Computing and Applications
36 (2024) 617–637.
corr_author: '1'
date_created: 2023-10-22T22:01:16Z
date_published: 2024-01-01T00:00:00Z
date_updated: 2025-04-23T07:39:14Z
day: '01'
ddc:
- '000'
department:
- _id: JuFi
doi: 10.1007/s00521-023-09033-7
ec_funded: 1
external_id:
arxiv:
- '2203.04579'
pmid:
- '38187995'
file:
- access_level: open_access
checksum: 04573d8e74c6119b97c2ca0a984e19a1
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T08:08:54Z
date_updated: 2024-07-16T08:08:54Z
file_id: '17251'
file_name: 2024_NeuralCompApplications_Cornalba.pdf
file_size: 4412285
relation: main_file
success: 1
file_date_updated: 2024-07-16T08:08:54Z
has_accepted_license: '1'
intvolume: ' 36'
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 617-637
pmid: 1
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Neural Computing and Applications
publication_identifier:
eissn:
- 1433-3058
issn:
- 0941-0643
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Multi-objective reward generalization: Improving performance of Deep Reinforcement
Learning for applications in single-asset trading'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14463'
abstract:
- lang: eng
text: Inversions are thought to play a key role in adaptation and speciation, suppressing
recombination between diverging populations. Genes influencing adaptive traits
cluster in inversions, and changes in inversion frequencies are associated with
environmental differences. However, in many organisms, it is unclear if inversions
are geographically and taxonomically widespread. The intertidal snail, Littorina
saxatilis, is one such example. Strong associations between putative polymorphic
inversions and phenotypic differences have been demonstrated between two ecotypes
of L. saxatilis in Sweden and inferred elsewhere, but no direct evidence for inversion
polymorphism currently exists across the species range. Using whole genome data
from 107 snails, most inversion polymorphisms were found to be widespread across
the species range. The frequencies of some inversion arrangements were significantly
different among ecotypes, suggesting a parallel adaptive role. Many inversions
were also polymorphic in the sister species, L. arcana, hinting at an ancient
origin.
acknowledgement: We would like to thank members of the Littorina team for their advice
and feedback during this project. In particular, we thank Alan Le Moan, who inspired
us to look at heterozygosity differences to identify inversions, and Katherine Hearn
for helping with the PCA scripts. We thank Edinburgh Genomics for library preparation
and sequencing. Sample collections, sequencing and data preparation were supported
by the European Research Council (ERC-2015-AdG-693030- BARRIERS) and the Natural
Environment Research Council (NE/P001610/1). The analysis was supported by the Swedish
Research Council (vetenskaprådet; 2018-03695_VR) and the Portuguese Foundation for
Science and Technology (Fundación para a Ciência e Tecnologia) through a research
project (PTDC/BIA-EVL/1614/2021) and CEEC contract (2020.00275.CEECIND).
article_number: e17160
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: James
full_name: Reeve, James
last_name: Reeve
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Eva L.
full_name: Koch, Eva L.
last_name: Koch
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
citation:
ama: Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. Chromosomal inversion polymorphisms
are widespread across the species ranges of rough periwinkles (Littorina saxatilis
and L. arcana). Molecular Ecology. 2024;33(24). doi:10.1111/mec.17160
apa: Reeve, J., Butlin, R. K., Koch, E. L., Stankowski, S., & Faria, R. (2024).
Chromosomal inversion polymorphisms are widespread across the species ranges of
rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology.
Wiley. https://doi.org/10.1111/mec.17160
chicago: Reeve, James, Roger K. Butlin, Eva L. Koch, Sean Stankowski, and Rui Faria.
“Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges
of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology.
Wiley, 2024. https://doi.org/10.1111/mec.17160.
ieee: J. Reeve, R. K. Butlin, E. L. Koch, S. Stankowski, and R. Faria, “Chromosomal
inversion polymorphisms are widespread across the species ranges of rough periwinkles
(Littorina saxatilis and L. arcana),” Molecular Ecology, vol. 33, no. 24.
Wiley, 2024.
ista: Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. 2024. Chromosomal inversion
polymorphisms are widespread across the species ranges of rough periwinkles (Littorina
saxatilis and L. arcana). Molecular Ecology. 33(24), e17160.
mla: Reeve, James, et al. “Chromosomal Inversion Polymorphisms Are Widespread across
the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).”
Molecular Ecology, vol. 33, no. 24, e17160, Wiley, 2024, doi:10.1111/mec.17160.
short: J. Reeve, R.K. Butlin, E.L. Koch, S. Stankowski, R. Faria, Molecular Ecology
33 (2024).
date_created: 2023-10-29T23:01:17Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-01-09T07:53:18Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.17160
external_id:
isi:
- '001085119000001'
pmid:
- '37843465'
file:
- access_level: open_access
checksum: 686576036663f489c2d079df3079d126
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T07:52:12Z
date_updated: 2025-01-09T07:52:12Z
file_id: '18785'
file_name: 2024_MolecularEcology_Reeve.pdf
file_size: 6228700
relation: main_file
success: 1
file_date_updated: 2025-01-09T07:52:12Z
has_accepted_license: '1'
intvolume: ' 33'
isi: 1
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Molecular Ecology
publication_identifier:
eissn:
- 1365-294X
issn:
- 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromosomal inversion polymorphisms are widespread across the species ranges
of rough periwinkles (Littorina saxatilis and L. arcana)
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2024'
...
---
APC_amount: 3040,36 EUR
OA_place: publisher
OA_type: hybrid
_id: '14478'
abstract:
- lang: eng
text: Entire chromosomes are typically only transmitted vertically from one generation
to the next. The horizontal transfer of such chromosomes has long been considered
improbable, yet gained recent support in several pathogenic fungi where it may
affect the fitness or host specificity. To date, it is unknown how these transfers
occur, how common they are and whether they can occur between different species.
In this study, we show multiple independent instances of horizontal transfers
of the same accessory chromosome between two distinct strains of the asexual entomopathogenic
fungusMetarhizium robertsiiduring experimental co-infection
of its insect host, the Argentine ant. Notably, only the one chromosome – but
no other – was transferred from the donor to the recipient strain. The recipient
strain, now harboring the accessory chromosome, exhibited a competitive advantage
under certain host conditions. By phylogenetic analysis we further demonstrate
that the same accessory chromosome was horizontally transferred in a natural environment
betweenM. robertsiiand another congeneric insect pathogen,M.
guizhouense. Hence horizontal chromosome transfer is not limited
to the observed frequent events within species during experimental infections
but also occurs naturally across species. The transferred accessory chromosome
contains genes that might be involved in its preferential horizontal transfer,
encoding putative histones and histone-modifying enzymes, but also putative virulence
factors that may support its establishment. Our study reveals that both intra-
and interspecies horizontal transfer of entire chromosomes is more frequent than
previously assumed, likely representing a not uncommon mechanism for gene exchange.Significance
StatementThe enormous success of bacterial pathogens has
been attributed to their ability to exchange genetic material between one another.
Similarly, in eukaryotes, horizontal transfer of genetic material allowed the
spread of virulence factors across species. The horizontal transfer of whole chromosomes
could be an important pathway for such exchange of genetic material, but little
is known about the origin of transferable chromosomes and how frequently they
are exchanged. Here, we show that the transfer of accessory chromosomes - chromosomes
that are non-essential but may provide fitness benefits - is common during fungal
co-infections and is even possible between distant pathogenic species, highlighting
the importance of horizontal gene transfer via chromosome transfer also for the
evolution and function of eukaryotic pathogens.
acknowledgement: We thank Bernhardt Steinwender, Jorgen Eilenberg, and Nicolai V.
Meyling for the fungal strains. We further thank Chengshu Wang for providing the
short sequencing reads for M. guizhouense ARESF977 he used for his published genome
assembly, and Kristian Ullrich for help in the bioinformatics analysis for methylation
pattern in Nanopore reads, and the VBC and the Max Planck Society for the use of
their sequencing centers. We thank Barbara Milutinović and Hinrich Schulenburg for
discussion, and Tal Dagan and Jens Rolff for comments on a previous version of the
manuscript. Fig. 1A was created with BioRender.com. This study received funding
by the European Research Council under the European Union’s Horizon 2020 Research
and Innovation Programme (No. 771402; EPIDEMICSonCHIP) to S.C. and by the German
Research Foundation (DFG grant HA9263/1-1) to M.H.
article_number: e2316284121
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Michael
full_name: Habig, Michael
last_name: Habig
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Judith
full_name: Müller, Judith
last_name: Müller
- first_name: Eva H.
full_name: Stukenbrock, Eva H.
last_name: Stukenbrock
- first_name: Hanna
full_name: Leitner, Hanna
id: 8fc5c6f6-5903-11ec-abad-c83f046253e7
last_name: Leitner
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. Frequent
horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings
of the National Academy of Sciences of the United States of America. 2024;121(11).
doi:10.1073/pnas.2316284121
apa: Habig, M., Grasse, A. V., Müller, J., Stukenbrock, E. H., Leitner, H., &
Cremer, S. (2024). Frequent horizontal chromosome transfer between asexual fungal
insect pathogens. Proceedings of the National Academy of Sciences of the United
States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2316284121
chicago: Habig, Michael, Anna V Grasse, Judith Müller, Eva H. Stukenbrock, Hanna
Leitner, and Sylvia Cremer. “Frequent Horizontal Chromosome Transfer between Asexual
Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of
the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2316284121.
ieee: M. Habig, A. V. Grasse, J. Müller, E. H. Stukenbrock, H. Leitner, and S. Cremer,
“Frequent horizontal chromosome transfer between asexual fungal insect pathogens,”
Proceedings of the National Academy of Sciences of the United States of America,
vol. 121, no. 11. National Academy of Sciences, 2024.
ista: Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. 2024. Frequent
horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings
of the National Academy of Sciences of the United States of America. 121(11),
e2316284121.
mla: Habig, Michael, et al. “Frequent Horizontal Chromosome Transfer between Asexual
Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of
the United States of America, vol. 121, no. 11, e2316284121, National Academy
of Sciences, 2024, doi:10.1073/pnas.2316284121.
short: M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer,
Proceedings of the National Academy of Sciences of the United States of America
121 (2024).
corr_author: '1'
date_created: 2023-10-31T13:30:00Z
date_published: 2024-03-12T00:00:00Z
date_updated: 2025-08-05T13:30:51Z
day: '12'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1073/pnas.2316284121
ec_funded: 1
external_id:
isi:
- '001207630200005'
pmid:
- '38442176'
file:
- access_level: open_access
checksum: f5e871db617b682edc71fcd08670dc81
content_type: application/pdf
creator: dernst
date_created: 2024-03-19T09:02:57Z
date_updated: 2024-03-19T09:02:57Z
file_id: '15124'
file_name: 2024_PNAS_Habig.pdf
file_size: 5750361
relation: main_file
success: 1
file_date_updated: 2024-03-19T09:02:57Z
has_accepted_license: '1'
intvolume: ' 121'
isi: 1
issue: '11'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2649B4DE-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '771402'
name: Epidemics in ant societies on a chip
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Frequent horizontal chromosome transfer between asexual fungal insect pathogens
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 121
year: '2024'
...
---
_id: '14479'
abstract:
- lang: eng
text: 'In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6
Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12
but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16
How nutrition influences host-parasite interactions is not well understood, as
studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23
We used the nutritional geometry framework24 to investigate the role of amino
acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant,
Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First,
using 18 diets varying in AA:C composition, we established that the fungus performed
best on the high-amino-acid diet 1:4. Second, we found that the fungus reached
this optimal diet when given various diet pairings, revealing its ability to cope
with nutritional challenges. Third, we showed that the optimal fungal diet reduced
the lifespan of healthy ants when compared with a high-carbohydrate diet but had
no effect on infected ants. Fourth, we revealed that infected ant colonies, given
a choice between the optimal fungal diet and a high-carbohydrate diet, chose the
optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling
fungal infection from host immune response, we demonstrated that infected ants
foraged on the optimal fungal diet in response to immune activation and not as
a result of parasite manipulation. Therefore, we revealed that infected ant colonies
chose a diet that is costly for survival in the long term but beneficial in the
short term—a form of collective self-medication.'
acknowledgement: We are sincerely grateful to the referees for their valuable comments
and suggestions, which helped us to improve the paper. We are thankful to Jorgen
Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou,
and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard,
Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore,
we thank Anna V. Grasse for help with the immune gene expression analyses. We thank
Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen
Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by
the CNRS.
article_processing_charge: No
article_type: original
author:
- first_name: Eniko
full_name: Csata, Eniko
last_name: Csata
- first_name: Alfonso
full_name: Perez-Escudero, Alfonso
last_name: Perez-Escudero
- first_name: Emmanuel
full_name: Laury, Emmanuel
last_name: Laury
- first_name: Hanna
full_name: Leitner, Hanna
id: 8fc5c6f6-5903-11ec-abad-c83f046253e7
last_name: Leitner
- first_name: Gerard
full_name: Latil, Gerard
last_name: Latil
- first_name: Juerge
full_name: Heinze, Juerge
last_name: Heinze
- first_name: Stephen
full_name: Simpson, Stephen
last_name: Simpson
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Audrey
full_name: Dussutour, Audrey
last_name: Dussutour
citation:
ama: Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective
nutritional intake of ant colonies. Current Biology. 2024;34(4):902-909.e6.
doi:10.1016/j.cub.2024.01.017
apa: Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J.,
… Dussutour, A. (2024). Fungal infection alters collective nutritional intake
of ant colonies. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2024.01.017
chicago: Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard
Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal
Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology.
Elsevier, 2024. https://doi.org/10.1016/j.cub.2024.01.017.
ieee: E. Csata et al., “Fungal infection alters collective nutritional intake
of ant colonies,” Current Biology, vol. 34, no. 4. Elsevier, p. 902–909.e6,
2024.
ista: Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson
S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional
intake of ant colonies. Current Biology. 34(4), 902–909.e6.
mla: Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake
of Ant Colonies.” Current Biology, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6,
doi:10.1016/j.cub.2024.01.017.
short: E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S.
Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.
date_created: 2023-10-31T13:30:20Z
date_published: 2024-02-26T00:00:00Z
date_updated: 2025-08-05T13:29:38Z
day: '26'
department:
- _id: SyCr
doi: 10.1016/j.cub.2024.01.017
external_id:
isi:
- '001195884300001'
pmid:
- '38307022'
intvolume: ' 34'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2023.10.26.564092
month: '02'
oa: 1
oa_version: Preprint
page: 902-909.e6
pmid: 1
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fungal infection alters collective nutritional intake of ant colonies
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
---
_id: '14488'
abstract:
- lang: eng
text: 'Portrait viewpoint and illumination editing is an important problem with
several applications in VR/AR, movies, and photography. Comprehensive knowledge
of geometry and illumination is critical for obtaining photorealistic results.
Current methods are unable to explicitly model in 3D while handling both viewpoint
and illumination editing from a single image. In this paper, we propose VoRF,
a novel approach that can take even a single portrait image as input and relight
human heads under novel illuminations that can be viewed from arbitrary viewpoints.
VoRF represents a human head as a continuous volumetric field and learns a prior
model of human heads using a coordinate-based MLP with individual latent spaces
for identity and illumination. The prior model is learned in an auto-decoder manner
over a diverse class of head shapes and appearances, allowing VoRF to generalize
to novel test identities from a single input image. Additionally, VoRF has a reflectance
MLP that uses the intermediate features of the prior model for rendering One-Light-at-A-Time
(OLAT) images under novel views. We synthesize novel illuminations by combining
these OLAT images with target environment maps. Qualitative and quantitative evaluations
demonstrate the effectiveness of VoRF for relighting and novel view synthesis,
even when applied to unseen subjects under uncontrolled illumination. This work
is an extension of Rao et al. (VoRF: Volumetric Relightable Faces 2022). We provide
extensive evaluation and ablative studies of our model and also provide an application,
where any face can be relighted using textual input.'
acknowledgement: Open Access funding enabled and organized by Projekt DEAL.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Pramod
full_name: Rao, Pramod
last_name: Rao
- first_name: B. R.
full_name: Mallikarjun, B. R.
last_name: Mallikarjun
- first_name: Gereon
full_name: Fox, Gereon
last_name: Fox
- first_name: Tim
full_name: Weyrich, Tim
last_name: Weyrich
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Hanspeter
full_name: Pfister, Hanspeter
last_name: Pfister
- first_name: Wojciech
full_name: Matusik, Wojciech
last_name: Matusik
- first_name: Fangneng
full_name: Zhan, Fangneng
last_name: Zhan
- first_name: Ayush
full_name: Tewari, Ayush
last_name: Tewari
- first_name: Christian
full_name: Theobalt, Christian
last_name: Theobalt
- first_name: Mohamed
full_name: Elgharib, Mohamed
last_name: Elgharib
citation:
ama: Rao P, Mallikarjun BR, Fox G, et al. A deeper analysis of volumetric relightiable
faces. International Journal of Computer Vision. 2024;132:1148-1166. doi:10.1007/s11263-023-01899-3
apa: Rao, P., Mallikarjun, B. R., Fox, G., Weyrich, T., Bickel, B., Pfister, H.,
… Elgharib, M. (2024). A deeper analysis of volumetric relightiable faces. International
Journal of Computer Vision. Springer Nature. https://doi.org/10.1007/s11263-023-01899-3
chicago: Rao, Pramod, B. R. Mallikarjun, Gereon Fox, Tim Weyrich, Bernd Bickel,
Hanspeter Pfister, Wojciech Matusik, et al. “A Deeper Analysis of Volumetric Relightiable
Faces.” International Journal of Computer Vision. Springer Nature, 2024.
https://doi.org/10.1007/s11263-023-01899-3.
ieee: P. Rao et al., “A deeper analysis of volumetric relightiable faces,”
International Journal of Computer Vision, vol. 132. Springer Nature, pp.
1148–1166, 2024.
ista: Rao P, Mallikarjun BR, Fox G, Weyrich T, Bickel B, Pfister H, Matusik W, Zhan
F, Tewari A, Theobalt C, Elgharib M. 2024. A deeper analysis of volumetric relightiable
faces. International Journal of Computer Vision. 132, 1148–1166.
mla: Rao, Pramod, et al. “A Deeper Analysis of Volumetric Relightiable Faces.” International
Journal of Computer Vision, vol. 132, Springer Nature, 2024, pp. 1148–66,
doi:10.1007/s11263-023-01899-3.
short: P. Rao, B.R. Mallikarjun, G. Fox, T. Weyrich, B. Bickel, H. Pfister, W. Matusik,
F. Zhan, A. Tewari, C. Theobalt, M. Elgharib, International Journal of Computer
Vision 132 (2024) 1148–1166.
date_created: 2023-11-05T23:00:54Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-08-05T13:28:58Z
day: '01'
ddc:
- '000'
department:
- _id: BeBi
doi: 10.1007/s11263-023-01899-3
external_id:
isi:
- '001091935600002'
pmid:
- '38549787'
file:
- access_level: open_access
checksum: 5eef1d920f6fe700d7856098000d05f1
content_type: application/pdf
creator: dernst
date_created: 2024-07-22T11:07:14Z
date_updated: 2024-07-22T11:07:14Z
file_id: '17304'
file_name: 2024_IJCV_Rao.pdf
file_size: 9942520
relation: main_file
success: 1
file_date_updated: 2024-07-22T11:07:14Z
has_accepted_license: '1'
intvolume: ' 132'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1148-1166
pmid: 1
publication: International Journal of Computer Vision
publication_identifier:
eissn:
- 1573-1405
issn:
- 0920-5691
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A deeper analysis of volumetric relightiable faces
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 132
year: '2024'
...
---
_id: '14543'
abstract:
- lang: eng
text: The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed,
plays a role in the acylation of lipids and proteins, and regulates the N-myristoylation
of proteins via N-myristoyltransferase enzymes (NMTs). However, its precise function
in cells is still unclear, as is the consequence of ACBD6 defects on human pathophysiology.
Utilizing exome sequencing and extensive international data sharing efforts, we
identified 45 affected individuals from 28 unrelated families (consanguinity 93%)
with bi-allelic pathogenic, predominantly loss-of-function (18/20) variants in
ACBD6. We generated zebrafish and Xenopus tropicalis acbd6 knockouts by CRISPR/Cas9
and characterized the role of ACBD6 on protein N-myristoylation with YnMyr chemical
proteomics in the model organisms and human cells, with the latter also being
subjected further to ACBD6 peroxisomal localization studies. The affected individuals
(23 males and 22 females), with ages ranging from 1 to 50 years old, typically
present with a complex and progressive disease involving moderate-to-severe global
developmental delay/intellectual disability (100%) with significant expressive
language impairment (98%), movement disorders (97%), facial dysmorphism (95%),
and mild cerebellar ataxia (85%) associated with gait impairment (94%), limb spasticity/hypertonia
(76%), oculomotor (71%) and behavioural abnormalities (65%), overweight (59%),
microcephaly (39%) and epilepsy (33%). The most conspicuous and common movement
disorder was dystonia (94%), frequently leading to early-onset progressive postural
deformities (97%), limb dystonia (55%), and cervical dystonia (31%). A jerky tremor
in the upper limbs (63%), a mild head tremor (59%), parkinsonism/hypokinesia developing
with advancing age (32%), and simple motor and vocal tics were among other frequent
movement disorders. Midline brain malformations including corpus callosum abnormalities
(70%), hypoplasia/agenesis of the anterior commissure (66%), short midbrain and
small inferior cerebellar vermis (38% each), as well as hypertrophy of the clava
(24%) were common neuroimaging findings. acbd6-deficient zebrafish and Xenopus
models effectively recapitulated many clinical phenotypes reported in patients
including movement disorders, progressive neuromotor impairment, seizures, microcephaly,
craniofacial dysmorphism, and midbrain defects accompanied by developmental delay
with increased mortality over time. Unlike ACBD5, ACBD6 did not show a peroxisomal
localisation and ACBD6-deficiency was not associated with altered peroxisomal
parameters in patient fibroblasts. Significant differences in YnMyr-labelling
were observed for 68 co- and 18 post-translationally N-myristoylated proteins
in patient-derived fibroblasts. N-Myristoylation was similarly affected in acbd6-deficient
zebrafish and Xenopus tropicalis models, including Fus, Marcks, and Chchd-related
proteins implicated in neurological diseases. The present study provides evidence
that bi-allelic pathogenic variants in ACBD6 lead to a distinct neurodevelopmental
syndrome accompanied by complex and progressive cognitive and movement disorders.
article_processing_charge: No
article_type: original
author:
- first_name: Rauan
full_name: Kaiyrzhanov, Rauan
last_name: Kaiyrzhanov
- first_name: Aboulfazl
full_name: Rad, Aboulfazl
last_name: Rad
- first_name: Sheng-Jia
full_name: Lin, Sheng-Jia
last_name: Lin
- first_name: Aida
full_name: Bertoli-Avella, Aida
last_name: Bertoli-Avella
- first_name: Wouter W
full_name: Kallemeijn, Wouter W
last_name: Kallemeijn
- first_name: Annie
full_name: Godwin, Annie
last_name: Godwin
- first_name: Maha S
full_name: Zaki, Maha S
last_name: Zaki
- first_name: Kevin
full_name: Huang, Kevin
id: 3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3
last_name: Huang
orcid: 0000-0002-2512-7812
- first_name: Tracy
full_name: Lau, Tracy
last_name: Lau
- first_name: Cassidy
full_name: Petree, Cassidy
last_name: Petree
- first_name: Stephanie
full_name: Efthymiou, Stephanie
last_name: Efthymiou
- first_name: Ehsan
full_name: Ghayoor Karimiani, Ehsan
last_name: Ghayoor Karimiani
- first_name: Maja
full_name: Hempel, Maja
last_name: Hempel
- first_name: Elizabeth A
full_name: Normand, Elizabeth A
last_name: Normand
- first_name: Sabine
full_name: Rudnik-Schöneborn, Sabine
last_name: Rudnik-Schöneborn
- first_name: Ulrich A
full_name: Schatz, Ulrich A
last_name: Schatz
- first_name: Marc P
full_name: Baggelaar, Marc P
last_name: Baggelaar
- first_name: Muhammad
full_name: Ilyas, Muhammad
last_name: Ilyas
- first_name: Tipu
full_name: Sultan, Tipu
last_name: Sultan
- first_name: Javeria Raza
full_name: Alvi, Javeria Raza
last_name: Alvi
- first_name: Manizha
full_name: Ganieva, Manizha
last_name: Ganieva
- first_name: Ben
full_name: Fowler, Ben
last_name: Fowler
- first_name: Ruxandra
full_name: Aanicai, Ruxandra
last_name: Aanicai
- first_name: Gulsen
full_name: Akay Tayfun, Gulsen
last_name: Akay Tayfun
- first_name: Abdulaziz
full_name: Al Saman, Abdulaziz
last_name: Al Saman
- first_name: Abdulrahman
full_name: Alswaid, Abdulrahman
last_name: Alswaid
- first_name: Nafise
full_name: Amiri, Nafise
last_name: Amiri
- first_name: Nilufar
full_name: Asilova, Nilufar
last_name: Asilova
- first_name: Vorasuk
full_name: Shotelersuk, Vorasuk
last_name: Shotelersuk
- first_name: Patra
full_name: Yeetong, Patra
last_name: Yeetong
- first_name: Matloob
full_name: Azam, Matloob
last_name: Azam
- first_name: Meisam
full_name: Babaei, Meisam
last_name: Babaei
- first_name: Gholamreza
full_name: Bahrami Monajemi, Gholamreza
last_name: Bahrami Monajemi
- first_name: Pouria
full_name: Mohammadi, Pouria
last_name: Mohammadi
- first_name: Saeed
full_name: Samie, Saeed
last_name: Samie
- first_name: Selina Husna
full_name: Banu, Selina Husna
last_name: Banu
- first_name: Jorge Pinto
full_name: Basto, Jorge Pinto
last_name: Basto
- first_name: Fanny
full_name: Kortüm, Fanny
last_name: Kortüm
- first_name: Mislen
full_name: Bauer, Mislen
last_name: Bauer
- first_name: Peter
full_name: Bauer, Peter
last_name: Bauer
- first_name: Christian
full_name: Beetz, Christian
last_name: Beetz
- first_name: Masoud
full_name: Garshasbi, Masoud
last_name: Garshasbi
- first_name: Awatif
full_name: Hameed Issa, Awatif
last_name: Hameed Issa
- first_name: Wafaa
full_name: Eyaid, Wafaa
last_name: Eyaid
- first_name: Hind
full_name: Ahmed, Hind
last_name: Ahmed
- first_name: Narges
full_name: Hashemi, Narges
last_name: Hashemi
- first_name: Kazem
full_name: Hassanpour, Kazem
last_name: Hassanpour
- first_name: Isabella
full_name: Herman, Isabella
last_name: Herman
- first_name: Sherozjon
full_name: Ibrohimov, Sherozjon
last_name: Ibrohimov
- first_name: Ban A
full_name: Abdul-Majeed, Ban A
last_name: Abdul-Majeed
- first_name: Maria
full_name: Imdad, Maria
last_name: Imdad
- first_name: Maksudjon
full_name: Isrofilov, Maksudjon
last_name: Isrofilov
- first_name: Qassem
full_name: Kaiyal, Qassem
last_name: Kaiyal
- first_name: Suliman
full_name: Khan, Suliman
last_name: Khan
- first_name: Brian
full_name: Kirmse, Brian
last_name: Kirmse
- first_name: Janet
full_name: Koster, Janet
last_name: Koster
- first_name: Charles Marques
full_name: Lourenço, Charles Marques
last_name: Lourenço
- first_name: Tadahiro
full_name: Mitani, Tadahiro
last_name: Mitani
- first_name: Oana
full_name: Moldovan, Oana
last_name: Moldovan
- first_name: David
full_name: Murphy, David
last_name: Murphy
- first_name: Maryam
full_name: Najafi, Maryam
last_name: Najafi
- first_name: Davut
full_name: Pehlivan, Davut
last_name: Pehlivan
- first_name: Maria Eugenia
full_name: Rocha, Maria Eugenia
last_name: Rocha
- first_name: Vincenzo
full_name: Salpietro, Vincenzo
last_name: Salpietro
- first_name: Miriam
full_name: Schmidts, Miriam
last_name: Schmidts
- first_name: Adel
full_name: Shalata, Adel
last_name: Shalata
- first_name: Mohammad
full_name: Mahroum, Mohammad
last_name: Mahroum
- first_name: Jawabreh Kassem
full_name: Talbeya, Jawabreh Kassem
last_name: Talbeya
- first_name: Robert W
full_name: Taylor, Robert W
last_name: Taylor
- first_name: Dayana
full_name: Vazquez, Dayana
last_name: Vazquez
- first_name: Annalisa
full_name: Vetro, Annalisa
last_name: Vetro
- first_name: Hans R
full_name: Waterham, Hans R
last_name: Waterham
- first_name: Mashaya
full_name: Zaman, Mashaya
last_name: Zaman
- first_name: Tina A
full_name: Schrader, Tina A
last_name: Schrader
- first_name: Wendy K
full_name: Chung, Wendy K
last_name: Chung
- first_name: Renzo
full_name: Guerrini, Renzo
last_name: Guerrini
- first_name: James R
full_name: Lupski, James R
last_name: Lupski
- first_name: Joseph
full_name: Gleeson, Joseph
last_name: Gleeson
- first_name: Mohnish
full_name: Suri, Mohnish
last_name: Suri
- first_name: Yalda
full_name: Jamshidi, Yalda
last_name: Jamshidi
- first_name: Kailash P
full_name: Bhatia, Kailash P
last_name: Bhatia
- first_name: Barbara
full_name: Vona, Barbara
last_name: Vona
- first_name: Michael
full_name: Schrader, Michael
last_name: Schrader
- first_name: Mariasavina
full_name: Severino, Mariasavina
last_name: Severino
- first_name: Matthew
full_name: Guille, Matthew
last_name: Guille
- first_name: Edward W
full_name: Tate, Edward W
last_name: Tate
- first_name: Gaurav K
full_name: Varshney, Gaurav K
last_name: Varshney
- first_name: Henry
full_name: Houlden, Henry
last_name: Houlden
- first_name: Reza
full_name: Maroofian, Reza
last_name: Maroofian
citation:
ama: Kaiyrzhanov R, Rad A, Lin S-J, et al. Bi-allelic ACBD6 variants lead to a neurodevelopmental
syndrome with progressive and complex movement disorders. Brain. 2024;147(4):1436-1456.
doi:10.1093/brain/awad380
apa: Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W.,
Godwin, A., … Maroofian, R. (2024). Bi-allelic ACBD6 variants lead to a neurodevelopmental
syndrome with progressive and complex movement disorders. Brain. Oxford
University Press. https://doi.org/10.1093/brain/awad380
chicago: Kaiyrzhanov, Rauan, Aboulfazl Rad, Sheng-Jia Lin, Aida Bertoli-Avella,
Wouter W Kallemeijn, Annie Godwin, Maha S Zaki, et al. “Bi-Allelic ACBD6 Variants
Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.”
Brain. Oxford University Press, 2024. https://doi.org/10.1093/brain/awad380.
ieee: R. Kaiyrzhanov et al., “Bi-allelic ACBD6 variants lead to a neurodevelopmental
syndrome with progressive and complex movement disorders,” Brain, vol.
147, no. 4. Oxford University Press, pp. 1436–1456, 2024.
ista: Kaiyrzhanov R, Rad A, Lin S-J, Bertoli-Avella A, Kallemeijn WW, Godwin A,
Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Ghayoor Karimiani E, Hempel M,
Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi
JR, Ganieva M, Fowler B, Aanicai R, Akay Tayfun G, Al Saman A, Alswaid A, Amiri
N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Bahrami Monajemi G,
Mohammadi P, Samie S, Banu SH, Basto JP, Kortüm F, Bauer M, Bauer P, Beetz C,
Garshasbi M, Hameed Issa A, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman
I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse
B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D,
Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW,
Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski
JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M,
Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R. 2024. Bi-allelic ACBD6
variants lead to a neurodevelopmental syndrome with progressive and complex movement
disorders. Brain. 147(4), 1436–1456.
mla: Kaiyrzhanov, Rauan, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental
Syndrome with Progressive and Complex Movement Disorders.” Brain, vol.
147, no. 4, Oxford University Press, 2024, pp. 1436–56, doi:10.1093/brain/awad380.
short: R. Kaiyrzhanov, A. Rad, S.-J. Lin, A. Bertoli-Avella, W.W. Kallemeijn, A.
Godwin, M.S. Zaki, K. Huang, T. Lau, C. Petree, S. Efthymiou, E. Ghayoor Karimiani,
M. Hempel, E.A. Normand, S. Rudnik-Schöneborn, U.A. Schatz, M.P. Baggelaar, M.
Ilyas, T. Sultan, J.R. Alvi, M. Ganieva, B. Fowler, R. Aanicai, G. Akay Tayfun,
A. Al Saman, A. Alswaid, N. Amiri, N. Asilova, V. Shotelersuk, P. Yeetong, M.
Azam, M. Babaei, G. Bahrami Monajemi, P. Mohammadi, S. Samie, S.H. Banu, J.P.
Basto, F. Kortüm, M. Bauer, P. Bauer, C. Beetz, M. Garshasbi, A. Hameed Issa,
W. Eyaid, H. Ahmed, N. Hashemi, K. Hassanpour, I. Herman, S. Ibrohimov, B.A. Abdul-Majeed,
M. Imdad, M. Isrofilov, Q. Kaiyal, S. Khan, B. Kirmse, J. Koster, C.M. Lourenço,
T. Mitani, O. Moldovan, D. Murphy, M. Najafi, D. Pehlivan, M.E. Rocha, V. Salpietro,
M. Schmidts, A. Shalata, M. Mahroum, J.K. Talbeya, R.W. Taylor, D. Vazquez, A.
Vetro, H.R. Waterham, M. Zaman, T.A. Schrader, W.K. Chung, R. Guerrini, J.R. Lupski,
J. Gleeson, M. Suri, Y. Jamshidi, K.P. Bhatia, B. Vona, M. Schrader, M. Severino,
M. Guille, E.W. Tate, G.K. Varshney, H. Houlden, R. Maroofian, Brain 147 (2024)
1436–1456.
date_created: 2023-11-16T12:36:51Z
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date_updated: 2024-07-16T08:23:24Z
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title: Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive
and complex movement disorders
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