---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21488'
abstract:
- lang: eng
text: Human height is a model for the genetic analysis of complex traits, and recent
studies suggest the presence of thousands of common genetic variant associations
and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic
paradigm based on approximate message passing (genomic vector approximate message
passing [gVAMP]) for identifying DNA sequence variants associated with complex
traits and common diseases in large-scale whole-genome sequencing (WGS) data.
We show that gVAMP accurately localizes associations to variants with the correct
frequency and position in the DNA, outperforming existing fine-mapping methods
in selecting the appropriate genetic variants within WGS data. We then apply gVAMP
to jointly model the relationship of tens of millions of WGS variants with human
height in hundreds of thousands of UK Biobank individuals. We identify 59 rare
variants and gene burden scores alongside many hundreds of DNA regions containing
common variant associations and show that understanding the genetic basis of complex
traits will require the joint analysis of hundreds of millions of variables measured
on millions of people. The polygenic risk scores obtained from gVAMP have high
accuracy (including a prediction accuracy of ∼46% for human height) and outperform
current methods for downstream tasks such as mixed linear model association testing
across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation
for a wider range of analyses in WGS data.
acknowledgement: We thank Malgorzata Borczyk for creating the gene burden scores.
We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter,
Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for
providing valuable suggestions and comments on earlier versions of the work. This
project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to
M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364),
and core funding from ISTA. High-performance computing was supported by the Scientific
Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).
We would like to acknowledge the participants and investigators of the UK Biobank
study. We gratefully acknowledge the All of Us participants for their contributions,
without whom this research would not have been possible. We also thank the National
Institutes of Health All of Us Research Program for making available the participant
data (and/or samples and/or cohort) examined in this study.
article_number: '101162'
article_processing_charge: Yes
article_type: original
author:
- first_name: Al
full_name: Depope, Al
id: 0b77531d-dbcd-11ea-9d1d-a8eee0bf3830
last_name: Depope
- first_name: Jakub
full_name: Bajzik, Jakub
id: b995e25b-8c4b-11ed-a6d8-f71b7bcd6122
last_name: Bajzik
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
citation:
ama: Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome
sequencing data for human height via approximate message passing. Cell Genomics.
2026. doi:10.1016/j.xgen.2026.101162
apa: Depope, A., Bajzik, J., Mondelli, M., & Robinson, M. R. (2026). Joint modeling
of whole-genome sequencing data for human height via approximate message passing.
Cell Genomics. Elsevier. https://doi.org/10.1016/j.xgen.2026.101162
chicago: Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson.
“Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate
Message Passing.” Cell Genomics. Elsevier, 2026. https://doi.org/10.1016/j.xgen.2026.101162.
ieee: A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of
whole-genome sequencing data for human height via approximate message passing,”
Cell Genomics. Elsevier, 2026.
ista: Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome
sequencing data for human height via approximate message passing. Cell Genomics.,
101162.
mla: Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human
Height via Approximate Message Passing.” Cell Genomics, 101162, Elsevier,
2026, doi:10.1016/j.xgen.2026.101162.
short: A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics (2026).
corr_author: '1'
date_created: 2026-03-23T15:10:03Z
date_published: 2026-02-18T00:00:00Z
date_updated: 2026-04-28T12:08:37Z
day: '18'
ddc:
- '000'
- '570'
department:
- _id: MaMo
- _id: MaRo
doi: 10.1016/j.xgen.2026.101162
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.xgen.2026.101162
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
name: Prix Lopez-Loretta 2019 - Marco Mondelli
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
grant_number: '101161364'
name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
grant_number: PCEGP3_181181
name: Improving estimation and prediction of common complex disease risk
publication: Cell Genomics
publication_identifier:
eissn:
- 2666-979X
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: press_release
url: https://ista.ac.at/en/news/big-data-and-human-height/
status: public
title: Joint modeling of whole-genome sequencing data for human height via approximate
message passing
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
_id: '21489'
abstract:
- lang: eng
text: We study Kirillov algebras attached to minuscule highest weight representations
of semisimple Lie algebras. They can be viewed as equivariant cohomology algebras
of partial flag varieties. Real structures on the varieties then induce involutions
of these algebras. We describe how these involutions act on the spectra of minuscule
Kirillov algebras, and model the fixed points via the equivariant cohomology of
real partial flag varieties. We then use this model to characterise freeness of
the fixed point coordinate ring over the appropriate base. As an application,
we recover a q = -1 phenomenon of Stembridge in the minuscule case by geometric
means.
acknowledgement: 'I would like to thank Tamás Hausel for introducing me to this area
of mathematics and for his constant guidance. I would also like to thank Jakub Löwit
and Miguel González for fruitful discussions and many helpful comments on this paper.
This work was done during the author’s PhD studies at the Institute of Science and
Technology Austria (ISTA). It was funded by the Austrian Science Fund (FWF) 10.55776/P35847.
Open access funding provided by Institute of Science and Technology (IST Austria). '
article_processing_charge: Yes (via OA deal)
arxiv: 1
author:
- first_name: Mischa M
full_name: Elkner, Mischa M
id: 477faa59-080d-11ed-979a-c693ab7638ab
last_name: Elkner
citation:
ama: Elkner MM. On involutions of minuscule Kirillov algebras induced by real structures.
Transformation Groups. 2026. doi:10.1007/s00031-026-09958-y
apa: Elkner, M. M. (2026). On involutions of minuscule Kirillov algebras induced
by real structures. Transformation Groups. Springer Nature. https://doi.org/10.1007/s00031-026-09958-y
chicago: Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced
by Real Structures.” Transformation Groups. Springer Nature, 2026. https://doi.org/10.1007/s00031-026-09958-y.
ieee: M. M. Elkner, “On involutions of minuscule Kirillov algebras induced by real
structures,” Transformation Groups. Springer Nature, 2026.
ista: Elkner MM. 2026. On involutions of minuscule Kirillov algebras induced by
real structures. Transformation Groups.
mla: Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by
Real Structures.” Transformation Groups, Springer Nature, 2026, doi:10.1007/s00031-026-09958-y.
short: M.M. Elkner, Transformation Groups (2026).
corr_author: '1'
date_created: 2026-03-23T15:10:43Z
date_published: 2026-03-14T00:00:00Z
date_updated: 2026-03-24T08:26:10Z
day: '14'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1007/s00031-026-09958-y
external_id:
arxiv:
- '2411.16270'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s00031-026-09958-y
month: '03'
oa: 1
oa_version: None
project:
- _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3
grant_number: P35847
name: Geometry of the tip of the global nilpotent cone
publication: Transformation Groups
publication_identifier:
eissn:
- 1531-586X
issn:
- 1083-4362
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On involutions of minuscule Kirillov algebras induced by real structures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21490'
abstract:
- lang: eng
text: Auxin canalization is a self-organizing process that governs the flexible
formation of vasculature by reinforcing the formation of auxin transport channels.
A key prerequisite is the feedback between auxin signaling and directional auxin
transport, mediated by PIN transporters. Despite the developmental importance
of canalization, the molecular components linking auxin perception to the regulation
of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel
and essential component of auxin canalization that links intracellular auxin signaling
with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23
transcriptional auxin signaling. tow mutants exhibit defects in regeneration and
de novo vasculature formation, along with impaired formation of polarized, PIN-expressing
auxin channels. At the subcellular level, these mutants display disrupted auxin-induced
PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes
predominantly to the plasma membrane, where it interacts with receptor-like kinases
involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR
complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at
the cell surface. Together, our findings identify TOW as a molecular link between
intracellular and cell surface auxin signaling mechanisms that converge on PIN
trafficking and polarity, providing new insights into how auxin signaling regulates
directional auxin transport for the self-organizing formation of vasculature during
flexible plant development.
acknowledged_ssus:
- _id: MassSpec
- _id: Bio
- _id: LifeSc
acknowledgement: We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9
system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof.
Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions,
and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also
acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging
& Optics Facility, and the Lab Support Facility at the Institute of Science and
Technology Austria. This research was supported by the Scientific Service Units
(SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF)
and the Lab Support Facility (LSF). The work conducted by the Friml group was funded
by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS)
and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the
core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant
Sciences Core Facility of CEITEC Masaryk University. E.M. received support from
the National Science Centre (NCN), Poland, through the OPUS call within the Weave
programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next
GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes
Amos Comenius.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Mingyue
full_name: Li, Mingyue
id: 01f96916-0235-11eb-9379-a323192643b7
last_name: Li
- first_name: Nikola
full_name: Rydza, Nikola
last_name: Rydza
- first_name: Ewa
full_name: Mazur, Ewa
last_name: Mazur
- first_name: Gergely
full_name: Molnar, Gergely
id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
last_name: Molnar
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization. Current Biology.
2026;36(6):1468-1480.e6. doi:10.1016/j.cub.2026.02.023
apa: Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., & Friml, J. (2026).
Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin
canalization. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2026.02.023
chicago: Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński,
and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters
for Auxin Canalization.” Current Biology. Elsevier, 2026. https://doi.org/10.1016/j.cub.2026.02.023.
ieee: M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization,” Current Biology,
vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026.
ista: Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization. Current Biology.
36(6), 1468–1480.e6.
mla: Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes
PIN Transporters for Auxin Canalization.” Current Biology, vol. 36, no.
6, Elsevier, 2026, p. 1468–1480.e6, doi:10.1016/j.cub.2026.02.023.
short: M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology
36 (2026) 1468–1480.e6.
corr_author: '1'
date_created: 2026-03-23T15:11:16Z
date_published: 2026-03-23T00:00:00Z
date_updated: 2026-03-24T08:36:40Z
day: '23'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.cub.2026.02.023
external_id:
pmid:
- '41831441'
file:
- access_level: open_access
checksum: fe6c41fdab58a55df5f2a5860c02acdc
content_type: application/pdf
creator: dernst
date_created: 2026-03-24T08:34:37Z
date_updated: 2026-03-24T08:34:37Z
file_id: '21496'
file_name: 2026_CurrentBiology_Li.pdf
file_size: 12986894
relation: main_file
success: 1
file_date_updated: 2026-03-24T08:34:37Z
has_accepted_license: '1'
intvolume: ' 36'
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1468-1480.e6
pmid: 1
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
grant_number: '101142681'
name: Cyclic nucleotides as second messengers in plants
- _id: bd906599-d553-11ed-ba76-abf8547645d7
grant_number: E271
name: Identification of a novel regulator in auxin canalization
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for
auxin canalization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21501'
abstract:
- lang: eng
text: "Kinetically constrained models were originally introduced to capture slow
relaxation in glassy systems, where dynamics are hindered by local constraints
instead of energy barriers. Their quantum counterparts have recently drawn attention
for exhibiting highly degenerate eigenstates at zero energy—known as zero modes—stemming
from chiral symmetry. Yet, the structure and implications of these zero modes
remain poorly understood. In this work, we focus on the properties of the zero
mode subspace in quantum kinetically constrained models with a U(1) particle-conservation
symmetry. We use the U(1) East, which lacks inversion symmetry, and the inversion-symmetric
U(1) East-West models to illustrate our two main results. First, we observe that
the simultaneous presence of constraints and chiral symmetry generally leads to
a parametric increase in the number of zero modes due to the fragmentation of
the many-body\r\nHilbert space into disconnected sectors. Second, we generalize
the concept of compact localized states from single-particle physics and introduce
the notion of collective bound states, a special kind of nonergodic eigenstates
that are robust to enlarging the system size. We formulate sufficient criteria
for their existence, arguing that the degenerate zero mode subspace plays a central
role, and demonstrate bound states in both example models and in a two-dimensional
model, the U(1) North-East, and in the pairflip model, a system without particle
conservation. Our results motivate a systematic study of bound states and their
relation to ergodicity breaking, transport, and other properties of quantum kinetically
constrained\r\nmodels. "
acknowledgement: The authors acknowledge useful discussions with Berislav Buca. This
work was supported by the European Research Council (ERC) under the European Union’s
Horizon 2020 research and innovation program (Grant Agreement No. 850899). M.L.
acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research
Foundation) under Germany’s Excellence Strategy—EXC-2111—390814868. This research
was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical
Physics (KITP).
article_number: '010352'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Eulalia
full_name: Nicolau Jimenez, Eulalia
id: 04b4791c-8fd7-11ee-a7df-be2fdc569c48
last_name: Nicolau Jimenez
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Nicolau Jimenez E, Ljubotina M, Serbyn M. Fragmentation, zero modes, and collective
bound states in constrained models. PRX Quantum. 2026;7. doi:10.1103/sl79-1xgb
apa: Nicolau Jimenez, E., Ljubotina, M., & Serbyn, M. (2026). Fragmentation,
zero modes, and collective bound states in constrained models. PRX Quantum.
American Physical Society. https://doi.org/10.1103/sl79-1xgb
chicago: Nicolau Jimenez, Eulalia, Marko Ljubotina, and Maksym Serbyn. “Fragmentation,
Zero Modes, and Collective Bound States in Constrained Models.” PRX Quantum.
American Physical Society, 2026. https://doi.org/10.1103/sl79-1xgb.
ieee: E. Nicolau Jimenez, M. Ljubotina, and M. Serbyn, “Fragmentation, zero modes,
and collective bound states in constrained models,” PRX Quantum, vol. 7.
American Physical Society, 2026.
ista: Nicolau Jimenez E, Ljubotina M, Serbyn M. 2026. Fragmentation, zero modes,
and collective bound states in constrained models. PRX Quantum. 7, 010352.
mla: Nicolau Jimenez, Eulalia, et al. “Fragmentation, Zero Modes, and Collective
Bound States in Constrained Models.” PRX Quantum, vol. 7, 010352, American
Physical Society, 2026, doi:10.1103/sl79-1xgb.
short: E. Nicolau Jimenez, M. Ljubotina, M. Serbyn, PRX Quantum 7 (2026).
corr_author: '1'
date_created: 2026-03-28T14:57:56Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-03-30T06:09:28Z
day: '13'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/sl79-1xgb
ec_funded: 1
external_id:
arxiv:
- '2504.17627'
file:
- access_level: open_access
checksum: d155ffa9e1a8275702149165f4bf963c
content_type: application/pdf
creator: dernst
date_created: 2026-03-30T06:08:07Z
date_updated: 2026-03-30T06:08:07Z
file_id: '21505'
file_name: 2026_PRXQuantum_Nicolau.pdf
file_size: 1848724
relation: main_file
success: 1
file_date_updated: 2026-03-30T06:08:07Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: PRX Quantum
publication_identifier:
eissn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fragmentation, zero modes, and collective bound states in constrained models
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21502'
abstract:
- lang: eng
text: The mammalian brain stores glucose, the main circulating energy substrate,
as glycogen. In rodents, the cerebellum contains relatively high glycogen levels,
yet its cellular and subcellular distribution remains poorly defined. Using monoclonal
antibodies against glycogen, we examined its distribution in the mouse cerebellar
cortex. Glycogen was predominantly localized to Bergmann glia (BG) processes in
the molecular layer and was also detected in Purkinje cells (PCs), the principal
cerebellar neurons. To assess the functional significance of cerebellar glycogen,
we analyzed behavior in mice lacking glycogen synthase 1 (Gys1) in BG or PCs using
a floxed Gys1 line. Gys1 deficiency in either PCs or GFAP-positive cells reduced
anxiety-like behavior, whereas combined deletion caused PC degeneration and ataxia.
These findings reveal a critical role for glycogen metabolism in both astrocytes
and neurons in cerebellar function.
acknowledgement: This work was supported by the Novo Nordisk Foundation (NNFOC0058058,
H. Hirase), the Danmarks Frie Forskningsfond (0134-00107B and 5283-00069A, H.Hirase),
the Lundbeck Foundation, Japan Society for the Promotion of Science Grants-in-Aid
for Scientific Research (KAKENHI) program (22K06454/24H01221, A.K.; 23K27482, H.Hirai),
the Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated
Neurotechnologies for Disease Studies (Brain/MINDS) (JP21dm0207111, H. Hirai), AMED
Brain/MINDS 2.0 (JP23wm0625001 and JP24wm0625103, H. Hirai), and grants from the
Spanish Ministerio de Ciencia e Innovación (MCIU/FEDER/AEI) (PID2020-118699 GB-100,
J.D.) and the Fundación Ramón Areces (J.D.). Sonam Akther has been supported by
the RIKEN IPA fellowship. We are thankful to Dr. Yuki Oe for his support in the
initial stage of this study and to Dan Xue for his help with the graphical abstract.
We thank Dr. Pia Weikop for providing CTN research infrastructure. The authors declare
no competing financial interests.
article_number: '115192'
article_processing_charge: Yes
article_type: original
author:
- first_name: Sonam
full_name: Akther, Sonam
last_name: Akther
- first_name: Ashley Bomin
full_name: Lee, Ashley Bomin
last_name: Lee
- first_name: Ayumu
full_name: Konno, Ayumu
last_name: Konno
- first_name: Antonis
full_name: Asiminas, Antonis
last_name: Asiminas
- first_name: Marta
full_name: Vittani, Marta
last_name: Vittani
- first_name: Tsuneko
full_name: Mishima, Tsuneko
last_name: Mishima
- first_name: Hirokazu
full_name: Hirai, Hirokazu
last_name: Hirai
- first_name: Claire Francesca
full_name: Meehan, Claire Francesca
last_name: Meehan
- first_name: Jordi
full_name: Duran, Jordi
last_name: Duran
- first_name: Joan
full_name: Guinovart, Joan
last_name: Guinovart
- first_name: Hitoshi
full_name: Ashida, Hitoshi
last_name: Ashida
- first_name: Tsuyoshi
full_name: Morita, Tsuyoshi
last_name: Morita
- first_name: Otto
full_name: Baba, Otto
last_name: Baba
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Maiken
full_name: Nedergaard, Maiken
last_name: Nedergaard
- first_name: Hajime
full_name: Hirase, Hajime
last_name: Hirase
citation:
ama: Akther S, Lee AB, Konno A, et al. Distribution and functional significance
of rodent cerebellar glycogen. iScience. 2026;29(4). doi:10.1016/j.isci.2026.115192
apa: Akther, S., Lee, A. B., Konno, A., Asiminas, A., Vittani, M., Mishima, T.,
… Hirase, H. (2026). Distribution and functional significance of rodent cerebellar
glycogen. IScience. Elsevier. https://doi.org/10.1016/j.isci.2026.115192
chicago: Akther, Sonam, Ashley Bomin Lee, Ayumu Konno, Antonis Asiminas, Marta Vittani,
Tsuneko Mishima, Hirokazu Hirai, et al. “Distribution and Functional Significance
of Rodent Cerebellar Glycogen.” IScience. Elsevier, 2026. https://doi.org/10.1016/j.isci.2026.115192.
ieee: S. Akther et al., “Distribution and functional significance of rodent
cerebellar glycogen,” iScience, vol. 29, no. 4. Elsevier, 2026.
ista: Akther S, Lee AB, Konno A, Asiminas A, Vittani M, Mishima T, Hirai H, Meehan
CF, Duran J, Guinovart J, Ashida H, Morita T, Baba O, Shigemoto R, Nedergaard
M, Hirase H. 2026. Distribution and functional significance of rodent cerebellar
glycogen. iScience. 29(4), 115192.
mla: Akther, Sonam, et al. “Distribution and Functional Significance of Rodent Cerebellar
Glycogen.” IScience, vol. 29, no. 4, 115192, Elsevier, 2026, doi:10.1016/j.isci.2026.115192.
short: S. Akther, A.B. Lee, A. Konno, A. Asiminas, M. Vittani, T. Mishima, H. Hirai,
C.F. Meehan, J. Duran, J. Guinovart, H. Ashida, T. Morita, O. Baba, R. Shigemoto,
M. Nedergaard, H. Hirase, IScience 29 (2026).
date_created: 2026-03-29T22:07:07Z
date_published: 2026-03-17T00:00:00Z
date_updated: 2026-06-18T08:32:22Z
day: '17'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1016/j.isci.2026.115192
external_id:
pmid:
- '41890976'
intvolume: ' 29'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.isci.2026.115192
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: iScience
publication_identifier:
eissn:
- 2589-0042
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distribution and functional significance of rodent cerebellar glycogen
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21503'
abstract:
- lang: eng
text: Currently, pharmacogenetics relies on partially annotated star alleles, leaving
novel variants and complex haplotypes uninterpretable. Computational scoring frameworks
could overcome these limitations. Here, we comprehensively evaluated the ability
of existing (CADD, FATHMM-XF, PROVEAN, MutationAssessor, SIFT, PhyloP100, APF,
APF2) and novel (PharmGScore and PharmMLScore) variant effect predictors to assess
pharmacogenetic alleles in multiple scenarios. Altogether we analyzed 541 PharmVar
alleles, high‑throughput CYP2C9 and CYP2C19 mutational maps, and 200 642 UK Biobank
exomes linked with health records containing antidepressant treatment outcomes.
Many evaluated tools, especially ensemble frameworks, matched or exceeded star
allele classifications (ROC‑AUC up to 0.85 for allele definitions, 0.95 in vitro;
TPR up to 0.99 for exomes) and accurately predicted severe antidepressant adverse
events for carriers of deleterious variants in CYP2C19 (OR 1.20–1.35). Our findings
show that computational predictors deliver star allele accuracy while overcoming
their limitations. With additional validation, computational tools could enhance
clinical decision frameworks by enabling continuous scoring, incorporating previously
unknown variants, and providing genome-wide applicability.
acknowledgement: "This research has been conducted using the UK Biobank Resource under
Application Number 62979. We are grateful to the UK Biobank and all its voluntary
participants. This work used data provided by patients and collected by the NHS
as part of their care and support.\r\n\r\nThis study was funded by the National
Science Center, Poland: PRELUDIUM BIS-3 grant no. 2021/43/O/NZ7/01187 (development
and benchmarking of variant scores) and SONATINA 5 grant 2021/40/C/NZ2/00218 (UKB
analyses). Additional support came from the statutory funds of the Maj Institute
of Pharmacology PAS. We gratefully acknowledge Poland’s high-performance Infrastructure
PLGrid ACK Cyfronet AGH, for providing computer facilities and support within computational
grant no PLG/2022/015861. DMF and GEB were funded by NIH grants NIH R35GM152106
and UM1HG011969."
article_number: '8'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jacek
full_name: Hajto, Jacek
last_name: Hajto
- first_name: Marcin
full_name: Piechota, Marcin
last_name: Piechota
- first_name: Ilse
full_name: Krätschmer, Ilse
id: 30d4014e-7753-11eb-b44b-db6d61112e73
last_name: Krätschmer
orcid: 0000-0002-5636-9259
- first_name: Paula
full_name: Konowalska, Paula
last_name: Konowalska
- first_name: Gabriel E.
full_name: Boyle, Gabriel E.
last_name: Boyle
- first_name: Douglas M.
full_name: Fowler, Douglas M.
last_name: Fowler
- first_name: Malgorzata
full_name: Borczyk, Malgorzata
last_name: Borczyk
- first_name: Michal
full_name: Korostynski, Michal
last_name: Korostynski
citation:
ama: 'Hajto J, Piechota M, Krätschmer I, et al. Computational variant predictors
for pharmacogenomics: From evaluation of single alleles to assessment of adverse
drug reactions to antidepressants. Pharmacogenomics Journal. 2026;26(2).
doi:10.1038/s41397-026-00399-0'
apa: 'Hajto, J., Piechota, M., Krätschmer, I., Konowalska, P., Boyle, G. E., Fowler,
D. M., … Korostynski, M. (2026). Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants.
Pharmacogenomics Journal. Springer Nature. https://doi.org/10.1038/s41397-026-00399-0'
chicago: 'Hajto, Jacek, Marcin Piechota, Ilse Krätschmer, Paula Konowalska, Gabriel
E. Boyle, Douglas M. Fowler, Malgorzata Borczyk, and Michal Korostynski. “Computational
Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to
Assessment of Adverse Drug Reactions to Antidepressants.” Pharmacogenomics
Journal. Springer Nature, 2026. https://doi.org/10.1038/s41397-026-00399-0.'
ieee: 'J. Hajto et al., “Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants,”
Pharmacogenomics Journal, vol. 26, no. 2. Springer Nature, 2026.'
ista: 'Hajto J, Piechota M, Krätschmer I, Konowalska P, Boyle GE, Fowler DM, Borczyk
M, Korostynski M. 2026. Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants.
Pharmacogenomics Journal. 26(2), 8.'
mla: 'Hajto, Jacek, et al. “Computational Variant Predictors for Pharmacogenomics:
From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.”
Pharmacogenomics Journal, vol. 26, no. 2, 8, Springer Nature, 2026, doi:10.1038/s41397-026-00399-0.'
short: J. Hajto, M. Piechota, I. Krätschmer, P. Konowalska, G.E. Boyle, D.M. Fowler,
M. Borczyk, M. Korostynski, Pharmacogenomics Journal 26 (2026).
date_created: 2026-03-29T22:07:08Z
date_published: 2026-03-09T00:00:00Z
date_updated: 2026-03-30T07:10:50Z
day: '09'
ddc:
- '570'
department:
- _id: MaRo
doi: 10.1038/s41397-026-00399-0
external_id:
pmid:
- '41803106'
file:
- access_level: open_access
checksum: 2fd3d7e48b779ac24245f6c35449b89a
content_type: application/pdf
creator: dernst
date_created: 2026-03-30T07:04:08Z
date_updated: 2026-03-30T07:04:08Z
file_id: '21506'
file_name: 2026_PharmacogenomicsJour_Hajto.pdf
file_size: 2618963
relation: main_file
success: 1
file_date_updated: 2026-03-30T07:04:08Z
has_accepted_license: '1'
intvolume: ' 26'
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Pharmacogenomics Journal
publication_identifier:
eissn:
- 1473-1150
issn:
- ' 1470-269X'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Computational variant predictors for pharmacogenomics: From evaluation of
single alleles to assessment of adverse drug reactions to antidepressants'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21504'
abstract:
- lang: eng
text: Selecting an appropriate divergence measure is a critical aspect of machine
learning, as it directly impacts model performance. Among the most widely used,
we find the Kullback–Leibler (KL) divergence, originally introduced in kinetic
theory as a measure of relative entropy between probability distributions. Just
as in machine learning, the ability to quantify the proximity of probability distributions
plays a central role in kinetic theory. In this paper, we present a comparative
review of divergence measures rooted in kinetic theory, highlighting their theoretical
foundations and exploring their potential applications in machine learning and
artificial intelligence.
acknowledgement: "This work has been written within the activities of GNCS and GNFM
groups of INdAM (Italian\r\nNational Institute of High Mathematics). G.B. has been
funded by the European Union’s Horizon 2020 research and innovation programme under
the Marie Sklodowska-Curie grant agreement No 101034413. P.G. has been funded by
the European Union - NextGenerationEU, in the framework of the GRINSGrowing Resilient,
INclusive and Sustainable (GRINS PE00000018)."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Gennaro
full_name: Auricchio, Gennaro
last_name: Auricchio
- first_name: Giovanni
full_name: Brigati, Giovanni
id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1
last_name: Brigati
- first_name: Paolo
full_name: Giudici, Paolo
last_name: Giudici
- first_name: Giuseppe
full_name: Toscani, Giuseppe
last_name: Toscani
citation:
ama: 'Auricchio G, Brigati G, Giudici P, Toscani G. From kinetic theory to AI: A
rediscovery of high-dimensional divergences and their properties. Mathematical
Models and Methods in Applied Sciences. 2026. doi:10.1142/S0218202526410010'
apa: 'Auricchio, G., Brigati, G., Giudici, P., & Toscani, G. (2026). From kinetic
theory to AI: A rediscovery of high-dimensional divergences and their properties.
Mathematical Models and Methods in Applied Sciences. World Scientific Publishing.
https://doi.org/10.1142/S0218202526410010'
chicago: 'Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani.
“From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and
Their Properties.” Mathematical Models and Methods in Applied Sciences.
World Scientific Publishing, 2026. https://doi.org/10.1142/S0218202526410010.'
ieee: 'G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “From kinetic theory
to AI: A rediscovery of high-dimensional divergences and their properties,” Mathematical
Models and Methods in Applied Sciences. World Scientific Publishing, 2026.'
ista: 'Auricchio G, Brigati G, Giudici P, Toscani G. 2026. From kinetic theory to
AI: A rediscovery of high-dimensional divergences and their properties. Mathematical
Models and Methods in Applied Sciences.'
mla: 'Auricchio, Gennaro, et al. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional
Divergences and Their Properties.” Mathematical Models and Methods in Applied
Sciences, World Scientific Publishing, 2026, doi:10.1142/S0218202526410010.'
short: G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and
Methods in Applied Sciences (2026).
date_created: 2026-03-29T22:07:08Z
date_published: 2026-03-14T00:00:00Z
date_updated: 2026-03-30T06:56:35Z
day: '14'
department:
- _id: JaMa
doi: 10.1142/S0218202526410010
ec_funded: 1
external_id:
arxiv:
- '2507.11387'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2507.11387
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Mathematical Models and Methods in Applied Sciences
publication_identifier:
eissn:
- 1793-6314
issn:
- 0218-2025
publication_status: epub_ahead
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'From kinetic theory to AI: A rediscovery of high-dimensional divergences and
their properties'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21509'
abstract:
- lang: eng
text: Chromatin remodeling complexes mobilize nucleosomes and promote transcription
factor (TF) binding. Using ensemble and single-molecule assays combined with cryo-electron
microscopy (cryo-EM), we studied the interaction between pioneer TFs OCT4–SOX2
and the human BRG1/BRM-associated factor (BAF) complex on nucleosomes. BAF engages
TF-bound substrates in two orientations, placing OCT4–SOX2 at either the remodeler
ENTRY or EXIT site. At the ENTRY site, OCT4–SOX2 initially coexists with BAF without
structural interference. However, continued DNA translocation is expected to cause
collisions with bound TFs, which can trigger remodeling direction reversals or
may induce TF dissociation. To accommodate TFs at the EXIT site, BAF undergoes
structural rearrangements, and ensemble assays reveal a nucleosome subpopulation
translocating away from TF-binding sites. Moreover, single-molecule experiments
show that nucleosome-bound BAF frequently changes remodeling direction, and we
identify an ADP-bound remodeler conformation as a potential intermediate. Together,
these findings reveal key aspects of the conformational dynamics and remodeling
outcomes underlying BAF processing of TF-bound nucleosomes.
acknowledgement: We thank D. Hess, V. Iesmantavicius, and J. Seebacher (FMI Proteomics
and Protein Analysis Facility) for mass spectrometry support; S. Smallwood, K. Shimada,
D. Klein, and M. Schütz-Stoffregen for technical assistance; J. Côté and C. Lachance
for critical discussions; and members of the Thomä lab for helpful feedback. Support
for this work was provided to N.H.T. by the European Research Council under the
European Union’s Horizon 2020 research program (NucEM, no. 884331), the Novartis
Research Foundation, the Swiss National Science Foundation (SNF 31003A_179541, 310030_214852,
and Sinergia CRSII5_186230), and the Swiss Cancer Research (KFS-4980-02-2020 and
KFS-5933-08-2023). S.D. was supported by the European Research Council (DONUTS,
no. 101092623), the Knut and Alice Wallenberg Foundation (2024.0012), the Cancerfonden
(25 4453 Pj), and the Swedish Research Council (VR 03255). A.K.M. was supported
by a Human Frontier Science Program Long-Term Fellowship, and L.V. was supported
by an EMBO fellowship (ALTF 549-2021).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Joscha
full_name: Weiss, Joscha
last_name: Weiss
- first_name: Luca
full_name: Vecchia, Luca
last_name: Vecchia
- first_name: David
full_name: Domjan, David
last_name: Domjan
- first_name: Simone
full_name: Cavadini, Simone
last_name: Cavadini
- first_name: Anton
full_name: Sabantsev, Anton
last_name: Sabantsev
- first_name: Georg
full_name: Kempf, Georg
last_name: Kempf
- first_name: Ganesh R.
full_name: Pathare, Ganesh R.
last_name: Pathare
- first_name: Klaus
full_name: Brackmann, Klaus
last_name: Brackmann
- first_name: Alicia
full_name: Michael, Alicia
id: 6437c950-2a03-11ee-914d-d6476dd7b75c
last_name: Michael
orcid: 0000-0002-6080-839X
- first_name: Lukas
full_name: Kater, Lukas
last_name: Kater
- first_name: Eric
full_name: Hietter-Pfeiffer, Eric
last_name: Hietter-Pfeiffer
- first_name: Mina
full_name: Haddawi, Mina
last_name: Haddawi
- first_name: Urja P.
full_name: Kuber, Urja P.
last_name: Kuber
- first_name: Sandra
full_name: Mühlhäusser, Sandra
last_name: Mühlhäusser
- first_name: Ralph S.
full_name: Grand, Ralph S.
last_name: Grand
- first_name: Michael B.
full_name: Stadler, Michael B.
last_name: Stadler
- first_name: Sebastian
full_name: Deindl, Sebastian
last_name: Deindl
- first_name: Nicolas H.
full_name: Thomä, Nicolas H.
last_name: Thomä
citation:
ama: Weiss J, Vecchia L, Domjan D, et al. The human BAF chromatin remodeler processes
nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular Cell.
2026;86(4):625-639.e8. doi:10.1016/j.molcel.2026.01.021
apa: Weiss, J., Vecchia, L., Domjan, D., Cavadini, S., Sabantsev, A., Kempf, G.,
… Thomä, N. H. (2026). The human BAF chromatin remodeler processes nucleosomes
bound by pioneer transcription factors OCT4–SOX2. Molecular Cell. Elsevier.
https://doi.org/10.1016/j.molcel.2026.01.021
chicago: Weiss, Joscha, Luca Vecchia, David Domjan, Simone Cavadini, Anton Sabantsev,
Georg Kempf, Ganesh R. Pathare, et al. “The Human BAF Chromatin Remodeler Processes
Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” Molecular Cell.
Elsevier, 2026. https://doi.org/10.1016/j.molcel.2026.01.021.
ieee: J. Weiss et al., “The human BAF chromatin remodeler processes nucleosomes
bound by pioneer transcription factors OCT4–SOX2,” Molecular Cell, vol.
86, no. 4. Elsevier, p. 625–639.e8, 2026.
ista: Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR,
Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser
S, Grand RS, Stadler MB, Deindl S, Thomä NH. 2026. The human BAF chromatin remodeler
processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular
Cell. 86(4), 625–639.e8.
mla: Weiss, Joscha, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes
Bound by Pioneer Transcription Factors OCT4–SOX2.” Molecular Cell, vol.
86, no. 4, Elsevier, 2026, p. 625–639.e8, doi:10.1016/j.molcel.2026.01.021.
short: J. Weiss, L. Vecchia, D. Domjan, S. Cavadini, A. Sabantsev, G. Kempf, G.R.
Pathare, K. Brackmann, A.K. Michael, L. Kater, E. Hietter-Pfeiffer, M. Haddawi,
U.P. Kuber, S. Mühlhäusser, R.S. Grand, M.B. Stadler, S. Deindl, N.H. Thomä, Molecular
Cell 86 (2026) 625–639.e8.
date_created: 2026-03-30T11:58:48Z
date_published: 2026-02-19T00:00:00Z
date_updated: 2026-03-30T12:09:08Z
day: '19'
ddc:
- '570'
department:
- _id: AlMi
doi: 10.1016/j.molcel.2026.01.021
external_id:
pmid:
- '41679301'
file:
- access_level: open_access
checksum: e16a7315b64a706184b177ea1621523c
content_type: application/pdf
creator: dernst
date_created: 2026-03-30T12:04:38Z
date_updated: 2026-03-30T12:04:38Z
file_id: '21510'
file_name: 2026_MolecularCell_Weiss.pdf
file_size: 9786677
relation: main_file
success: 1
file_date_updated: 2026-03-30T12:04:38Z
has_accepted_license: '1'
intvolume: ' 86'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 625-639.e8
pmid: 1
publication: Molecular Cell
publication_identifier:
issn:
- 1097-2765
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription
factors OCT4–SOX2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 86
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21532'
abstract:
- lang: eng
text: 'Recent research in nanophotonics for scintillation-based imaging has demonstrated
promising improvements in scintillator performance. In parallel, advances in nanophotonics
have enabled wavefront control through metasurfaces, a capability that has transformed
fields such as microscopy by allowing tailored control of optical propagation.
This naturally raises the following question, which we address in this Perspective:
can wavefront-control strategies be leveraged to improve scintillation-based imaging?
To answer this question, we explore nanophotonic- and metasurface-enabled wavefront
control in scintillators to mitigate image blurring arising from their intrinsically
diffuse light emission. While depth-of-field extension in scintillation faces
fundamental limitations absent in microscopy, this approach reveals promising
avenues, including stacked scintillators, selective spatial-frequency enhancement,
and X-ray energy-dependent imaging. These results clarify the key distinctions
in adapting wavefront engineering to scintillation and its potential to enable
tailored detection strategies.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Joshua
full_name: Chen, Joshua
last_name: Chen
- first_name: Sachin
full_name: Vaidya, Sachin
last_name: Vaidya
- first_name: Simo
full_name: Pajovic, Simo
last_name: Pajovic
- first_name: Seou
full_name: Choi, Seou
last_name: Choi
- first_name: William
full_name: Michaels, William
last_name: Michaels
- first_name: Louis
full_name: Martin-Monier, Louis
last_name: Martin-Monier
- first_name: Juejun
full_name: Hu, Juejun
last_name: Hu
- first_name: Carol
full_name: Cogswell, Carol
last_name: Cogswell
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: Chen J, Vaidya S, Pajovic S, et al. Wavefront engineering for scintillation-based
imaging. ACS Photonics. 2026;13(7):1757–1766. doi:10.1021/acsphotonics.5c03124
apa: Chen, J., Vaidya, S., Pajovic, S., Choi, S., Michaels, W., Martin-Monier, L.,
… Soljačić, M. (2026). Wavefront engineering for scintillation-based imaging.
ACS Photonics. American Chemical Society. https://doi.org/10.1021/acsphotonics.5c03124
chicago: Chen, Joshua, Sachin Vaidya, Simo Pajovic, Seou Choi, William Michaels,
Louis Martin-Monier, Juejun Hu, Carol Cogswell, Charles Roques-Carmes, and Marin
Soljačić. “Wavefront Engineering for Scintillation-Based Imaging.” ACS Photonics.
American Chemical Society, 2026. https://doi.org/10.1021/acsphotonics.5c03124.
ieee: J. Chen et al., “Wavefront engineering for scintillation-based imaging,”
ACS Photonics, vol. 13, no. 7. American Chemical Society, pp. 1757–1766,
2026.
ista: Chen J, Vaidya S, Pajovic S, Choi S, Michaels W, Martin-Monier L, Hu J, Cogswell
C, Roques-Carmes C, Soljačić M. 2026. Wavefront engineering for scintillation-based
imaging. ACS Photonics. 13(7), 1757–1766.
mla: Chen, Joshua, et al. “Wavefront Engineering for Scintillation-Based Imaging.”
ACS Photonics, vol. 13, no. 7, American Chemical Society, 2026, pp. 1757–1766,
doi:10.1021/acsphotonics.5c03124.
short: J. Chen, S. Vaidya, S. Pajovic, S. Choi, W. Michaels, L. Martin-Monier, J.
Hu, C. Cogswell, C. Roques-Carmes, M. Soljačić, ACS Photonics 13 (2026) 1757–1766.
date_created: 2026-03-30T12:22:47Z
date_published: 2026-03-01T00:00:00Z
date_updated: 2026-05-05T07:53:27Z
day: '01'
doi: 10.1021/acsphotonics.5c03124
extern: '1'
external_id:
arxiv:
- '2601.09830'
intvolume: ' 13'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2601.09830
month: '03'
oa: 1
oa_version: Preprint
page: 1757–1766
publication: ACS Photonics
publication_identifier:
eissn:
- 2330-4022
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Wavefront engineering for scintillation-based imaging
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21537'
abstract:
- lang: eng
text: Nanophotonics has revolutionized the control of light-matter interactions
in various fields of fundamental science and technology. In this work, we propose
Implosion Fabrication (ImpFab) as a versatile nanophotonics fabrication platform
providing the highest spatial resolution, material versatility, and full volumetric
control. ImpFab uniquely combines top-down lithography with bottom-up nanoparticle
assembly within a hydrogel scaffold, enabling precise control over optical material
properties, such as refractive index, by adjusting printing parameters. We showcase
the potential of ImpFab by fabricating three-dimensional photonic crystals and
quasicrystals, as well as demonstrating optical structures with spatially modulated
unit cell material properties. Our results highlight the potential of ImpFab in
producing nanostructures with tailored optical functionalities, which are crucial
for applications in sensing, imaging, and information processing, and opening
new avenues in developing non-Hermitian photonic systems with spatially controlled
gain and loss.
article_number: '145'
article_processing_charge: No
article_type: original
author:
- first_name: Yannick
full_name: Salamin, Yannick
last_name: Salamin
- first_name: Gaojie
full_name: Yang, Gaojie
last_name: Yang
- first_name: Brian
full_name: Mills, Brian
last_name: Mills
- first_name: André
full_name: Grossi Fonseca, André
last_name: Grossi Fonseca
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Quansan
full_name: Yang, Quansan
last_name: Yang
- first_name: Justin
full_name: Beroz, Justin
last_name: Beroz
- first_name: Steven E.
full_name: Kooi, Steven E.
last_name: Kooi
- first_name: Marc
full_name: de Miguel Comella, Marc
last_name: de Miguel Comella
- first_name: Kiran
full_name: Mak, Kiran
last_name: Mak
- first_name: Sachin
full_name: Vaidya, Sachin
last_name: Vaidya
- first_name: Daniel
full_name: Oran, Daniel
last_name: Oran
- first_name: Corban
full_name: Swain, Corban
last_name: Swain
- first_name: Yi
full_name: Sun, Yi
last_name: Sun
- first_name: Shai
full_name: Maayani, Shai
last_name: Maayani
- first_name: Jamison
full_name: Sloan, Jamison
last_name: Sloan
- first_name: Amel
full_name: Amin Elfadil Elawad, Amel
last_name: Amin Elfadil Elawad
- first_name: Josue J.
full_name: Lopez, Josue J.
last_name: Lopez
- first_name: Edward S.
full_name: Boyden, Edward S.
last_name: Boyden
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: 'Salamin Y, Yang G, Mills B, et al. Three-dimensional nanophotonics with spatially
modulated optical properties. Light: Science & Applications. 2026;15.
doi:10.1038/s41377-025-02166-5'
apa: 'Salamin, Y., Yang, G., Mills, B., Grossi Fonseca, A., Roques-Carmes, C., Yang,
Q., … Soljačić, M. (2026). Three-dimensional nanophotonics with spatially modulated
optical properties. Light: Science & Applications. Springer Nature.
https://doi.org/10.1038/s41377-025-02166-5'
chicago: 'Salamin, Yannick, Gaojie Yang, Brian Mills, André Grossi Fonseca, Charles
Roques-Carmes, Quansan Yang, Justin Beroz, et al. “Three-Dimensional Nanophotonics
with Spatially Modulated Optical Properties.” Light: Science & Applications.
Springer Nature, 2026. https://doi.org/10.1038/s41377-025-02166-5.'
ieee: 'Y. Salamin et al., “Three-dimensional nanophotonics with spatially
modulated optical properties,” Light: Science & Applications, vol.
15. Springer Nature, 2026.'
ista: 'Salamin Y, Yang G, Mills B, Grossi Fonseca A, Roques-Carmes C, Yang Q, Beroz
J, Kooi SE, de Miguel Comella M, Mak K, Vaidya S, Oran D, Swain C, Sun Y, Maayani
S, Sloan J, Amin Elfadil Elawad A, Lopez JJ, Boyden ES, Soljačić M. 2026. Three-dimensional
nanophotonics with spatially modulated optical properties. Light: Science &
Applications. 15, 145.'
mla: 'Salamin, Yannick, et al. “Three-Dimensional Nanophotonics with Spatially Modulated
Optical Properties.” Light: Science & Applications, vol. 15, 145, Springer
Nature, 2026, doi:10.1038/s41377-025-02166-5.'
short: 'Y. Salamin, G. Yang, B. Mills, A. Grossi Fonseca, C. Roques-Carmes, Q. Yang,
J. Beroz, S.E. Kooi, M. de Miguel Comella, K. Mak, S. Vaidya, D. Oran, C. Swain,
Y. Sun, S. Maayani, J. Sloan, A. Amin Elfadil Elawad, J.J. Lopez, E.S. Boyden,
M. Soljačić, Light: Science & Applications 15 (2026).'
date_created: 2026-03-30T12:22:47Z
date_published: 2026-03-03T00:00:00Z
date_updated: 2026-04-27T07:59:10Z
day: '03'
ddc:
- '530'
doi: 10.1038/s41377-025-02166-5
extern: '1'
external_id:
pmid:
- ' 41775693'
intvolume: ' 15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41377-025-02166-5
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: 'Light: Science & Applications'
publication_identifier:
eissn:
- 2047-7538
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Three-dimensional nanophotonics with spatially modulated optical properties
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 15
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21555'
abstract:
- lang: eng
text: Spin-polarized electron beam sources enable studies of spin-dependent electric
and magnetic effects at the nanoscale. We propose a method of creating spin-polarized
electrons on an integrated photonics chip by laser-driven nanophotonic fields.
A two-stage interaction separated by a free-space drift length is proposed, where
the first stage and drift length introduces spin-dependent characteristics into
the probability distribution of the electron wave function. The second stage uses
an adjusted optical near field to rotate the spin states utilizing the spin-dependent
wave-packet distribution to produce electrons with high ensemble average spin
expectation values. This platform provides an integrated and compact method to
generate spin-polarized electrons, implementable with millimeter scale chips and
tabletop lasers.
article_number: '063802'
article_processing_charge: No
article_type: original
author:
- first_name: Clarisse
full_name: Woodahl, Clarisse
last_name: Woodahl
- first_name: Melanie
full_name: Murillo, Melanie
last_name: Murillo
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Aviv
full_name: Karnieli, Aviv
last_name: Karnieli
- first_name: David A. B.
full_name: Miller, David A. B.
last_name: Miller
- first_name: Olav
full_name: Solgaard, Olav
last_name: Solgaard
citation:
ama: Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O.
On-chip laser-driven free-electron spin polarizer. Physical Review Letters.
2026;136(6). doi:10.1103/3c1m-d3hh
apa: Woodahl, C., Murillo, M., Roques-Carmes, C., Karnieli, A., Miller, D. A. B.,
& Solgaard, O. (2026). On-chip laser-driven free-electron spin polarizer.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/3c1m-d3hh
chicago: Woodahl, Clarisse, Melanie Murillo, Charles Roques-Carmes, Aviv Karnieli,
David A. B. Miller, and Olav Solgaard. “On-Chip Laser-Driven Free-Electron Spin
Polarizer.” Physical Review Letters. American Physical Society, 2026. https://doi.org/10.1103/3c1m-d3hh.
ieee: C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D. A. B. Miller, and
O. Solgaard, “On-chip laser-driven free-electron spin polarizer,” Physical
Review Letters, vol. 136, no. 6. American Physical Society, 2026.
ista: Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O.
2026. On-chip laser-driven free-electron spin polarizer. Physical Review Letters.
136(6), 063802.
mla: Woodahl, Clarisse, et al. “On-Chip Laser-Driven Free-Electron Spin Polarizer.”
Physical Review Letters, vol. 136, no. 6, 063802, American Physical Society,
2026, doi:10.1103/3c1m-d3hh.
short: C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D.A.B. Miller, O.
Solgaard, Physical Review Letters 136 (2026).
date_created: 2026-03-30T12:22:47Z
date_published: 2026-02-12T00:00:00Z
date_updated: 2026-04-27T08:34:51Z
day: '12'
ddc:
- '530'
doi: 10.1103/3c1m-d3hh
extern: '1'
intvolume: ' 136'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1103/3c1m-d3hh
month: '02'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: On-chip laser-driven free-electron spin polarizer
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_type: closed access
_id: '21581'
abstract:
- lang: eng
text: We demonstrate that nanophotonic scintillators based on three-dimensional
(3D) photonic crystals can overcome the longstanding tradeoff between spatial
resolution and light yield in X-ray imaging. By engineering supercollimation,
which is light propagation without angular spreading, within the emission spectrum,
we strongly shape the angular emission profile of the scintillator, dramatically
reducing blurring at large thicknesses. Our theoretical and numerical results,
using realistic scintillator and photonic crystal parameters, show that this improves
the Detector Quantum Efficiency (DQE) by up to several orders of magnitude at
high spatial frequencies, enabling sharper images and reduced X-ray dosages. This
approach offers a new path toward high-resolution, low-dose X-ray imaging systems.
article_number: 'PC1391008 '
article_processing_charge: No
author:
- first_name: Sachin
full_name: Vaidya, Sachin
last_name: Vaidya
- first_name: Seou
full_name: Choi, Seou
last_name: Choi
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: 'Vaidya S, Choi S, Roques-Carmes C, Soljačić M. Supercollimating photonic crystal
scintillators. In: High Contrast Metastructures XV. Vol PC13910. SPIE;
2026. doi:10.1117/12.3079431'
apa: 'Vaidya, S., Choi, S., Roques-Carmes, C., & Soljačić, M. (2026). Supercollimating
photonic crystal scintillators. In High Contrast Metastructures XV (Vol.
PC13910). San Francisco, CA, United States: SPIE. https://doi.org/10.1117/12.3079431'
chicago: Vaidya, Sachin, Seou Choi, Charles Roques-Carmes, and Marin Soljačić. “Supercollimating
Photonic Crystal Scintillators.” In High Contrast Metastructures XV, Vol.
PC13910. SPIE, 2026. https://doi.org/10.1117/12.3079431.
ieee: S. Vaidya, S. Choi, C. Roques-Carmes, and M. Soljačić, “Supercollimating photonic
crystal scintillators,” in High Contrast Metastructures XV, San Francisco,
CA, United States, 2026, vol. PC13910.
ista: Vaidya S, Choi S, Roques-Carmes C, Soljačić M. 2026. Supercollimating photonic
crystal scintillators. High Contrast Metastructures XV. OPTO vol. PC13910, PC1391008.
mla: Vaidya, Sachin, et al. “Supercollimating Photonic Crystal Scintillators.” High
Contrast Metastructures XV, vol. PC13910, PC1391008, SPIE, 2026, doi:10.1117/12.3079431.
short: S. Vaidya, S. Choi, C. Roques-Carmes, M. Soljačić, in:, High Contrast Metastructures
XV, SPIE, 2026.
conference:
end_date: 2026-01-23
location: San Francisco, CA, United States
name: OPTO
start_date: 2026-01-17
date_created: 2026-03-30T12:22:48Z
date_published: 2026-02-01T00:00:00Z
date_updated: 2026-05-05T10:53:00Z
day: '01'
doi: 10.1117/12.3079431
extern: '1'
language:
- iso: eng
month: '02'
oa_version: None
publication: High Contrast Metastructures XV
publication_status: published
publisher: SPIE
quality_controlled: '1'
status: public
title: Supercollimating photonic crystal scintillators
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: PC13910
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21583'
abstract:
- lang: eng
text: Non-Hermiticity naturally arises in physical systems that exchange energy
with their environment. The presence of non-Hermiticity leads to many topological
physics phenomena and device applications. In the non-Hermitian energy band theory,
the foundation of these physics and applications, both energies and wave vectors
take complex values. The energy bands thus become a Riemann surface, and such
an energy-band Riemann surface underlies all important signatures of non-Hermitian
topology. Despite a long history and recent theoretical interests, the energy-band
Riemann surface has not been experimentally studied. Here, we provide a photonic
observation of the energy-band Riemann surface of a non-Hermitian system. This
is achieved by a tunable imaginary gauge transformation in photonic synthetic
frequency dimensions. From measured topologies of the Riemann surface, we reveal
the complex-energy winding, the open-boundary-condition spectrum, the generalized
Brillouin zone, and the branch points. Our findings demonstrate a unified framework
in the studies of diverse effects in non-Hermitian topological physics through
an experimental observation of energy-band Riemann surfaces.
article_number: eaec8239
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Dali
full_name: Cheng, Dali
last_name: Cheng
- first_name: Heming
full_name: Wang, Heming
last_name: Wang
- first_name: Janet
full_name: Zhong, Janet
last_name: Zhong
- first_name: Eran
full_name: Lustig, Eran
last_name: Lustig
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Shanhui
full_name: Fan, Shanhui
last_name: Fan
citation:
ama: Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. Experimental observation
of energy-band Riemann surface. Science Advances. 2026;12(12). doi:10.1126/sciadv.aec8239
apa: Cheng, D., Wang, H., Zhong, J., Lustig, E., Roques-Carmes, C., & Fan, S.
(2026). Experimental observation of energy-band Riemann surface. Science Advances.
American Association for the Advancement of Science. https://doi.org/10.1126/sciadv.aec8239
chicago: Cheng, Dali, Heming Wang, Janet Zhong, Eran Lustig, Charles Roques-Carmes,
and Shanhui Fan. “Experimental Observation of Energy-Band Riemann Surface.” Science
Advances. American Association for the Advancement of Science, 2026. https://doi.org/10.1126/sciadv.aec8239.
ieee: D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, and S. Fan, “Experimental
observation of energy-band Riemann surface,” Science Advances, vol. 12,
no. 12. American Association for the Advancement of Science, 2026.
ista: Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. 2026. Experimental
observation of energy-band Riemann surface. Science Advances. 12(12), eaec8239.
mla: Cheng, Dali, et al. “Experimental Observation of Energy-Band Riemann Surface.”
Science Advances, vol. 12, no. 12, eaec8239, American Association for the
Advancement of Science, 2026, doi:10.1126/sciadv.aec8239.
short: D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, S. Fan, Science
Advances 12 (2026).
date_created: 2026-03-30T12:22:48Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-27T10:01:35Z
day: '18'
doi: 10.1126/sciadv.aec8239
extern: '1'
external_id:
arxiv:
- '2510.08819'
intvolume: ' 12'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1126/sciadv.aec8239
month: '03'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_identifier:
issn:
- 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental observation of energy-band Riemann surface
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2026'
...
---
OA_place: publisher
_id: '21651'
abstract:
- lang: eng
text: "Blockchains enable distributed consensus in permissionless settings, where
participants\r\nare unknown, dynamically changing, and do not trust each other.
While Bitcoin,\r\nbased on Proof-of-Work (PoW), was the first protocol in this
model, significant\r\nresearch has focused on permissionless protocols using alternative
physical resources,\r\nspecifically Proof-of-Space (PoSpace) and Verifiable Delay
Functions (VDFs). This\r\nthesis investigates the theoretical limits and design
space of longest-chain protocols in\r\nthe fully permissionless and dynamically
available settings using these three resources.\r\nFirst, we address the feasibility
of blockchains relying solely on storage as a resource.\r\nWe prove a fundamental
impossibility result: there exists no secure longest-chain\r\nprotocol based exclusively
on Proof-of-Space in the fully permissionless or dynamically\r\navailable settings.
Further, we quantify the adversarial capabilities required to execute\r\na double-spend
attack. Our result formally justifies the necessity of coupling PoSpace\r\nwith
time-dependent primitives (such as VDFs) or to move to less permissive settings\r\n(quasi-permissionless
or permissioned) to ensure security.\r\nSecond, we generalize Nakamoto-like heaviest
chain consensus to protocols utilizing\r\ncombinations of multiple physical resources.
We analyze chain selection rules governed\r\nby a weight function Γ(S, V,W), which
assigns weight to blocks based on recorded\r\nSpace (S), VDF speed (V ), and Work
(W). We provide a complete classification\r\nof secure weight functions, proving
that a weight function is secure against private\r\ndouble-spend attacks if and
only if it is homogeneous in the timed resources (V,W)\r\nand sub-homogeneous
in S. This framework unifies existing protocols like Bitcoin and\r\nChia under
a single theoretical model and provides a powerful tool for designing new\r\nlongest-chain
blockchains from a mix of physical resources."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Mirza Ahad
full_name: Baig, Mirza Ahad
id: 3EDE6DE4-AA5A-11E9-986D-341CE6697425
last_name: Baig
citation:
ama: Baig MA. On secure chain selection rules from physical resources in a permissionless
setting. 2026. doi:10.15479/AT-ISTA-21651
apa: Baig, M. A. (2026). On secure chain selection rules from physical resources
in a permissionless setting. Institute of Science and Technology Austria.
https://doi.org/10.15479/AT-ISTA-21651
chicago: Baig, Mirza Ahad. “On Secure Chain Selection Rules from Physical Resources
in a Permissionless Setting.” Institute of Science and Technology Austria, 2026.
https://doi.org/10.15479/AT-ISTA-21651.
ieee: M. A. Baig, “On secure chain selection rules from physical resources in a
permissionless setting,” Institute of Science and Technology Austria, 2026.
ista: Baig MA. 2026. On secure chain selection rules from physical resources in
a permissionless setting. Institute of Science and Technology Austria.
mla: Baig, Mirza Ahad. On Secure Chain Selection Rules from Physical Resources
in a Permissionless Setting. Institute of Science and Technology Austria,
2026, doi:10.15479/AT-ISTA-21651.
short: M.A. Baig, On Secure Chain Selection Rules from Physical Resources in a Permissionless
Setting, Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-04-02T09:31:34Z
date_published: 2026-03-04T00:00:00Z
date_updated: 2026-04-15T08:45:19Z
day: '04'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrPi
doi: 10.15479/AT-ISTA-21651
file:
- access_level: closed
checksum: c3986dba90653dac97adba662ebff238
content_type: application/x-zip-compressed
creator: mbaig
date_created: 2026-04-03T17:28:48Z
date_updated: 2026-04-13T08:24:13Z
file_id: '21655'
file_name: PhD-Thesis-Mirza-Ahad-Baig - Library Submission.zip
file_size: 139353434
relation: source_file
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date_created: 2026-04-03T17:29:30Z
date_updated: 2026-04-15T07:37:25Z
file_id: '21656'
file_name: 2026_Baig_Mirza_Ahad_Thesis.pdf
file_size: 1942037
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language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '03'
oa: 1
oa_version: Published Version
publication_identifier:
isbn:
- 978-3-99078-078-7
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '21134'
relation: part_of_dissertation
status: public
- id: '20587'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
title: On secure chain selection rules from physical resources in a permissionless
setting
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21657'
abstract:
- lang: eng
text: We compare three global kilometer-scale models (ICON, IFS and NICAM) to clarify
the advantages and challenges of high-resolution global weather and climate modeling,
using different approaches to represent convection, from fully parameterized to
fully explicit. Our analysis focuses on tropical precipitation characteristics
spanning a wide range of spatio-temporal scales—including the diurnal cycle, extreme
precipitation, convective organization, and the Madden-Julian Oscillation (MJO)—along
with interactions between convection and the thermodynamic environment. All three
models commonly show weaker convective organization with smaller precipitation
cells than observed, though the strength of the bias varies by model. This diversity
is introduced by differences in the representation of (a) convective initiation
affected by the convective sensitivity to moisture and (b) tropospheric moistening
associated with deep convection. Models with stronger thermodynamic-convection
coupling increase environmental moisture near convection, thereby enhancing convective
organization. This has important upscale effects on the MJO; while IFS and NICAM
capture its eastward propagation well, ICON has difficulty reproducing it. The
amplitudes and phases of precipitation diurnal cycles over land show much greater
disagreement among the models than over ocean, influenced by how convection is
initiated. Biases in rain evaporation and cold pool formation hinder the propagation
of mesoscale convection, leading to errors such as the misrepresentation of nocturnal
convection moving off the coast of Sumatra in IFS and ICON. These results highlight
the importance of thermodynamic-convection coupling in realistically simulating
tropical convection across scales. To improve this coupling, kilometer-scale models
require better representation of the interaction between resolved convection and
three-dimensional turbulent mixing.
acknowledgement: 'We thank Peter Bechtold, Lukas Brunner, Peter Dueben, Richard Forbes,
Estibaliz Gascon, and Benoit Vanniere for providing insightful comments on the present
study. We also thank Sebastian Milinski, Xabier Pedruzo and Thomas Rackow for their
contributions to setting up IFS-FESOM for nextGEMS. We are also grateful to Dr.
Walter Hannah and an anonymous reviewer for their constructive comments, which improved
the original version of the manuscript. D. Takasuka was supported by JSPS KAKENHI
Grants 20H05728 and 24K22893 and by JSPS Core-to-Core Program, “International Core-to-Core
Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001). T.
Becker was supported by the Horizon 2020 project nextGEMS under grant agreement
number 101003470. J. Bao acknowledges funding from the European Union''s Horizon
2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant
agreement No 101034413). The ICON and IFS simulations were performed with supercomputing
resources of the German Climate Computing Centre (Deutsches Klimarechenzentrum,
DKRZ) granted by its Scientific Steering Committee (WLA) under project ID 1235.
The NICAM simulation was performed on the supercomputer Fugaku (proposal numbers
hp220132, hp230078, hp230108, hp230278, and hp240267).'
article_number: e2025MS005343
article_processing_charge: Yes
article_type: original
author:
- first_name: Daisuke
full_name: Takasuka, Daisuke
last_name: Takasuka
- first_name: Tobias
full_name: Becker, Tobias
last_name: Becker
- first_name: Jiawei
full_name: Bao, Jiawei
id: bb9a7399-fefd-11ed-be3c-ae648fd1d160
last_name: Bao
citation:
ama: Takasuka D, Becker T, Bao J. Precipitation characteristics and thermodynamic-convection
coupling in global kilometer-scale simulations. Journal of Advances in Modeling
Earth Systems. 2026;18(3). doi:10.1029/2025MS005343
apa: Takasuka, D., Becker, T., & Bao, J. (2026). Precipitation characteristics
and thermodynamic-convection coupling in global kilometer-scale simulations. Journal
of Advances in Modeling Earth Systems. Wiley. https://doi.org/10.1029/2025MS005343
chicago: Takasuka, Daisuke, Tobias Becker, and Jiawei Bao. “Precipitation Characteristics
and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.”
Journal of Advances in Modeling Earth Systems. Wiley, 2026. https://doi.org/10.1029/2025MS005343.
ieee: D. Takasuka, T. Becker, and J. Bao, “Precipitation characteristics and thermodynamic-convection
coupling in global kilometer-scale simulations,” Journal of Advances in Modeling
Earth Systems, vol. 18, no. 3. Wiley, 2026.
ista: Takasuka D, Becker T, Bao J. 2026. Precipitation characteristics and thermodynamic-convection
coupling in global kilometer-scale simulations. Journal of Advances in Modeling
Earth Systems. 18(3), e2025MS005343.
mla: Takasuka, Daisuke, et al. “Precipitation Characteristics and Thermodynamic-Convection
Coupling in Global Kilometer-Scale Simulations.” Journal of Advances in Modeling
Earth Systems, vol. 18, no. 3, e2025MS005343, Wiley, 2026, doi:10.1029/2025MS005343.
short: D. Takasuka, T. Becker, J. Bao, Journal of Advances in Modeling Earth Systems
18 (2026).
corr_author: '1'
date_created: 2026-04-05T22:01:31Z
date_published: 2026-03-01T00:00:00Z
date_updated: 2026-06-16T10:43:35Z
day: '01'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1029/2025MS005343
ec_funded: 1
file:
- access_level: open_access
checksum: ca7dac4bab31348d0640ed22580c6dce
content_type: application/pdf
creator: dernst
date_created: 2026-04-07T09:11:23Z
date_updated: 2026-04-07T09:11:23Z
file_id: '21665'
file_name: 2026_JAMES_Takasuka.pdf
file_size: 3854313
relation: main_file
success: 1
file_date_updated: 2026-04-07T09:11:23Z
has_accepted_license: '1'
intvolume: ' 18'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Journal of Advances in Modeling Earth Systems
publication_identifier:
eissn:
- 1942-2466
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Precipitation characteristics and thermodynamic-convection coupling in global
kilometer-scale simulations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '21658'
abstract:
- lang: eng
text: Dipolar (ℓ = 1) mixed modes have revealed a surprisingly weak differential
rotation between the core and the envelope of evolved solar-like stars. Quadrupolar
(ℓ = 2) mixed modes also contain information regarding internal dynamics but are
very rarely characterised due to their low amplitude and the challenging identification
of adjacent or overlapping rotationally split multiplets affected by near-degeneracy
effects. We aim to extend the broadly used asymptotic seismic diagnostics beyond
ℓ = 1 mixed modes by developing an analogue asymptotic description of ℓ = 2 mixed
modes while explicitly accounting for near-degeneracy effects that distort their
rotational multiplets. We have derived a new asymptotic formulation of near-degenerate
mixed ℓ = 2 modes that describes off-diagonal terms representing the interaction
between modes of adjacent radial orders. This formalism, expressed directly in
the mixed-mode basis, provides analytical expressions for the near-degeneracy
effects. We implemented the formalism within a global Bayesian mode-fitting framework
for a direct fit of all ℓ = 0, 1, 2 modes in the power spectrum density. We were
able to asymptotically model the asymmetric rotational splitting present in various
radial orders of ℓ = 2 modes observed in young red giant stars without the need
for any numerical stellar modelling. We applied our formalism to the Kepler target
KIC 7341231, and it yielded core and envelope rotation rates consistent with previous
numerical modelling while providing improved constraints from the global and model-independent
approach. We also characterised the new target, KIC 8179973, measuring its rotation
rate and mixed-mode parameters for the first time. As our framework relies on
a direct global fit, it allows for much better precision on the asteroseismic
parameters and rotation rate estimates than standard methods, yielding better
constraints for rotation inversions. We have placed the first observational constraints
on the asymptotic ℓ = 2 mixed-mode parameters (ΔΠ2, q2, and εg, 2), thus paving
the way towards the use of asymptotic seismology beyond ℓ = 1 mixed modes.
acknowledgement: 'We thank the referee for their careful and constructive report,
which has substantially enhanced both the quality and clarity of the manuscript.
L. Bugnet and L. Einramhof gratefully acknowledge support from the European Research
Council (ERC) under the Horizon Europe programme (Calcifer; Starting Grant agreement
N°101165631). While partially funded by the European Union, views and opinions expressed
are, however, those of the authors only and do not necessarily reflect those of
the European Union or the European Research Council. Neither the European Union
nor the granting authority can be held responsible for them. The authors acknowledge
the great support and feedback provided during the redaction of this article by
Pr. Rafael García and Pr. Savita Mathur. We would also like to thank Dr. Emily Hatt
for her insights on uncertainty estimates. The authors also thank the members of
the Asteroseismology and Stellar Dynamics group of the Institute of Science and
Technology Austria (ISTA) for very useful discussions: L. Barrault, S.B. Das, K.
Smith. This paper includes data collected by the Kepler mission and obtained from
the MAST data archive at the Space Telescope Science Institute (STScI). Funding
for the Kepler mission is provided by the NASA Science Mission Directorate. STScI
is operated by the Association of Universities for Research in Astronomy, Inc.,
under NASA contract NAS 5–26555. Software: AstroPy (Astropy Collaboration 2013,
2018), Matplotlib (Hunter 2007), NumPy (Harris et al. 2020), SciPy (Virtanen et
al. 2020), emcee (Foreman-Mackey et al. 2013), celerite (Foreman-Mackey et al. 2017),
slepc4py (Dalcin et al. 2011; Hernandez et al. 2005), KADACS (García et al. 2011),
sloscillations (Kuszlewicz et al. 2019, 2023).'
article_number: A321
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Bastien Raymond Bernard
full_name: Liagre, Bastien Raymond Bernard
id: 662f1873-cab4-11f0-a719-8087d302868d
last_name: Liagre
- first_name: Aayush A
full_name: Desai, Aayush A
id: 502cfd30-32c1-11ee-a9a4-d8dad5c6739e
last_name: Desai
- first_name: Lukas
full_name: Einramhof, Lukas
id: f1497a1a-72ef-11ef-b75a-fd877bbf6e8c
last_name: Einramhof
- first_name: Lisa Annabelle
full_name: Bugnet, Lisa Annabelle
id: d9edb345-f866-11ec-9b37-d119b5234501
last_name: Bugnet
orcid: 0000-0003-0142-4000
citation:
ama: 'Liagre BRB, Desai AA, Einramhof L, Bugnet LA. Near-degeneracy effects in quadrupolar
mixed modes: From an asymptotic description to data fitting. Astronomy and
Astrophysics. 2026;707. doi:10.1051/0004-6361/202558023'
apa: 'Liagre, B. R. B., Desai, A. A., Einramhof, L., & Bugnet, L. A. (2026).
Near-degeneracy effects in quadrupolar mixed modes: From an asymptotic description
to data fitting. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202558023'
chicago: 'Liagre, Bastien Raymond Bernard, Aayush A Desai, Lukas Einramhof, and
Lisa Annabelle Bugnet. “Near-Degeneracy Effects in Quadrupolar Mixed Modes: From
an Asymptotic Description to Data Fitting.” Astronomy and Astrophysics.
EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202558023.'
ieee: 'B. R. B. Liagre, A. A. Desai, L. Einramhof, and L. A. Bugnet, “Near-degeneracy
effects in quadrupolar mixed modes: From an asymptotic description to data fitting,”
Astronomy and Astrophysics, vol. 707. EDP Sciences, 2026.'
ista: 'Liagre BRB, Desai AA, Einramhof L, Bugnet LA. 2026. Near-degeneracy effects
in quadrupolar mixed modes: From an asymptotic description to data fitting. Astronomy
and Astrophysics. 707, A321.'
mla: 'Liagre, Bastien Raymond Bernard, et al. “Near-Degeneracy Effects in Quadrupolar
Mixed Modes: From an Asymptotic Description to Data Fitting.” Astronomy and
Astrophysics, vol. 707, A321, EDP Sciences, 2026, doi:10.1051/0004-6361/202558023.'
short: B.R.B. Liagre, A.A. Desai, L. Einramhof, L.A. Bugnet, Astronomy and Astrophysics
707 (2026).
corr_author: '1'
date_created: 2026-04-05T22:01:32Z
date_published: 2026-03-01T00:00:00Z
date_updated: 2026-04-07T09:01:44Z
day: '01'
ddc:
- '520'
department:
- _id: LiBu
- _id: IlCa
- _id: GradSch
doi: 10.1051/0004-6361/202558023
external_id:
arxiv:
- '2511.05314 '
file:
- access_level: open_access
checksum: 560cac19dc70184626b85e71a26ee22e
content_type: application/pdf
creator: dernst
date_created: 2026-04-07T09:00:50Z
date_updated: 2026-04-07T09:00:50Z
file_id: '21664'
file_name: 2026_AstronomyAstrophysics_Liagre.pdf
file_size: 12287607
relation: main_file
success: 1
file_date_updated: 2026-04-07T09:00:50Z
has_accepted_license: '1'
intvolume: ' 707'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Astronomy and Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Near-degeneracy effects in quadrupolar mixed modes: From an asymptotic description
to data fitting'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 707
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '21659'
abstract:
- lang: eng
text: The recent detection of solar equatorial Rossby waves has renewed interest
in the study of gravito-inertial waves propagating in the convective envelope
of solar-type stars. In particular, the ability of these envelope gravito-inertial
modes to couple with those trapped in the radiative interior could open up new
opportunities for probing the deep-layer dynamics of solar-type stars. The possibility
for such a coupling to occur is particularly favoured among pre-main-sequence
(PMS) solar-type stars. Indeed, due to the contraction of the protostellar object,
they are able to reach high rotation frequencies before nuclear reactions are
ignited and magnetic braking becomes the driving mechanism for their rotational
evolution. In this work, we studied the coupling between the envelope inertial
waves and the radiative interior g modes in PMS stars, focussing on the case of
prograde dipolar modes. We considered the cases of 0.5 M⊙ and 1 M⊙ PMS models,
each with three different scenarios of rotational evolution. We show that for
stars that have formed with a sufficient amount of angular momentum, this coupling
can occur in frequency ranges that are accessible to space-borne photometry, creating
inertial dips in the period spacing pattern. Using an asymptotic analysis, we
characterised the shape of these inertial dips to show that they depend on rotation
and on the stiffness of the convective-radiative interface.
acknowledgement: 'The authors want to thank the anonymous referee for useful comments.
SNB acknowledges support from PLATO ASI-INAF agreement no. 2022-28-HH.0 “PLATO Fase
D”. SNB and AFL acknowledge support from the INAF grant MASTODINT. CP thanks the
Belgian Federal Science Policy Office (BELSPO) for the financial support in the
framework of the PRODEX Program of the European Space Agency (ESA) under contract
number 4000141194. S.M acknowledges support from the CNES GOLF-SOHO and PLATO grants
at CEA/DAp. LB and SM gratefully acknowledge support from the European Research
Council (ERC) under the Horizon Europe programme (LB: Calcifer; Starting Grant agreement
N°101165631; SM: 4D-STAR; Synergy Grant agreement N°101071505). While partially
funded by the European Union, views and opinions expressed are, however, those of
the authors only and do not necessarily reflect those of the European Union or the
European Research Council. Neither the European Union nor the granting authority
can be held responsible for them. The authors acknowledge G. Buldgen, H. Dhouib,
and M.A. Dupret for fruitful discussions.'
article_number: L16
article_processing_charge: No
article_type: letter_editor
arxiv: 1
author:
- first_name: S. N.
full_name: Breton, S. N.
last_name: Breton
- first_name: C.
full_name: Pezzotti, C.
last_name: Pezzotti
- first_name: S.
full_name: Mathis, S.
last_name: Mathis
- first_name: Lisa Annabelle
full_name: Bugnet, Lisa Annabelle
id: d9edb345-f866-11ec-9b37-d119b5234501
last_name: Bugnet
orcid: 0000-0003-0142-4000
- first_name: M. P.
full_name: Di Mauro, M. P.
last_name: Di Mauro
- first_name: J.
full_name: Joergensen, J.
last_name: Joergensen
- first_name: K.
full_name: Zwintz, K.
last_name: Zwintz
- first_name: A. F.
full_name: Lanza, A. F.
last_name: Lanza
citation:
ama: Breton SN, Pezzotti C, Mathis S, et al. Core-envelope coupling of gravito-inertial
waves in pre-main-sequence solar-type stars. Astronomy & Astrophysics.
2026;707. doi:10.1051/0004-6361/202659309
apa: Breton, S. N., Pezzotti, C., Mathis, S., Bugnet, L. A., Di Mauro, M. P., Joergensen,
J., … Lanza, A. F. (2026). Core-envelope coupling of gravito-inertial waves in
pre-main-sequence solar-type stars. Astronomy & Astrophysics. Wiley.
https://doi.org/10.1051/0004-6361/202659309
chicago: Breton, S. N., C. Pezzotti, S. Mathis, Lisa Annabelle Bugnet, M. P. Di
Mauro, J. Joergensen, K. Zwintz, and A. F. Lanza. “Core-Envelope Coupling of Gravito-Inertial
Waves in Pre-Main-Sequence Solar-Type Stars.” Astronomy & Astrophysics.
Wiley, 2026. https://doi.org/10.1051/0004-6361/202659309.
ieee: S. N. Breton et al., “Core-envelope coupling of gravito-inertial waves
in pre-main-sequence solar-type stars,” Astronomy & Astrophysics, vol.
707. Wiley, 2026.
ista: Breton SN, Pezzotti C, Mathis S, Bugnet LA, Di Mauro MP, Joergensen J, Zwintz
K, Lanza AF. 2026. Core-envelope coupling of gravito-inertial waves in pre-main-sequence
solar-type stars. Astronomy & Astrophysics. 707, L16.
mla: Breton, S. N., et al. “Core-Envelope Coupling of Gravito-Inertial Waves in
Pre-Main-Sequence Solar-Type Stars.” Astronomy & Astrophysics, vol.
707, L16, Wiley, 2026, doi:10.1051/0004-6361/202659309.
short: S.N. Breton, C. Pezzotti, S. Mathis, L.A. Bugnet, M.P. Di Mauro, J. Joergensen,
K. Zwintz, A.F. Lanza, Astronomy & Astrophysics 707 (2026).
date_created: 2026-04-05T22:01:32Z
date_published: 2026-03-01T00:00:00Z
date_updated: 2026-04-07T09:23:27Z
day: '01'
ddc:
- '520'
department:
- _id: LiBu
doi: 10.1051/0004-6361/202659309
external_id:
arxiv:
- '2603.01979'
file:
- access_level: open_access
checksum: a7fd798bf450d67d4166fdf54ff2c70c
content_type: application/pdf
creator: dernst
date_created: 2026-04-07T09:20:02Z
date_updated: 2026-04-07T09:20:02Z
file_id: '21666'
file_name: 2026_AstronomyAstrophysics_Breton.pdf
file_size: 1535506
relation: main_file
success: 1
file_date_updated: 2026-04-07T09:20:02Z
has_accepted_license: '1'
intvolume: ' 707'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 914d8549-16d5-11f0-9cad-bbe6324c93a9
grant_number: '101165631'
name: 'Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology'
publication: Astronomy & Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Core-envelope coupling of gravito-inertial waves in pre-main-sequence solar-type
stars
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 707
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21660'
abstract:
- lang: eng
text: Kapitza-Dirac scattering, the diffraction of matter waves from a standing
light field, is widely utilized in ultracold gases, but its behavior in the strongly
interacting regime is an open question. Here, we develop a numerically exact two-body
description of Kapitza-Dirac scattering for two contact-interacting atoms in a
one-dimensional harmonic trap subjected to a pulsed optical lattice, enabling
us to obtain the numerically exact dynamics. We map how interaction strength,
lattice depth, lattice wave number, and pulse duration reshape the diffraction
pattern, leading to an interaction-dependent population redistribution in real
and momentum space. By comparing the exact dynamics to an impulsive sudden-approximation
description, we delineate the parameter regimes where it remains accurate and
those, notably at strong attraction and small lattice wave number, where it fails.
Our results provide a controlled few-body benchmark for interacting Kapitza-Dirac
scattering and quantitative guidance for Kapitza-Dirac-based probes of ultracold
atomic systems.
acknowledgement: We thank Max Hachmann, Andreas Hemmerich, and Yann Kiefer for valuable
discussions. This work has been funded by the Cluster of Excellence “Advanced Imaging
of Matter” of the Deutsche Forschungsgemeinschaft (DFG) - EXC 2056 - Project ID
390715994. G.M.K. has received funding by the Austrian Science Fund (FWF) 10.55776/F1004.
article_number: '013297'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: A.
full_name: Becker, A.
last_name: Becker
- first_name: Georgios
full_name: Koutentakis, Georgios
id: d7b23d3a-9e21-11ec-b482-f76739596b95
last_name: Koutentakis
- first_name: P.
full_name: Schmelcher, P.
last_name: Schmelcher
citation:
ama: Becker A, Koutentakis G, Schmelcher P. Two-body Kapitza-Dirac scattering of
one-dimensional ultracold atoms. Physical Review Research. 2026;8. doi:10.1103/rdsn-stlq
apa: Becker, A., Koutentakis, G., & Schmelcher, P. (2026). Two-body Kapitza-Dirac
scattering of one-dimensional ultracold atoms. Physical Review Research.
American Physical Society. https://doi.org/10.1103/rdsn-stlq
chicago: Becker, A., Georgios Koutentakis, and P. Schmelcher. “Two-Body Kapitza-Dirac
Scattering of One-Dimensional Ultracold Atoms.” Physical Review Research.
American Physical Society, 2026. https://doi.org/10.1103/rdsn-stlq.
ieee: A. Becker, G. Koutentakis, and P. Schmelcher, “Two-body Kapitza-Dirac scattering
of one-dimensional ultracold atoms,” Physical Review Research, vol. 8.
American Physical Society, 2026.
ista: Becker A, Koutentakis G, Schmelcher P. 2026. Two-body Kapitza-Dirac scattering
of one-dimensional ultracold atoms. Physical Review Research. 8, 013297.
mla: Becker, A., et al. “Two-Body Kapitza-Dirac Scattering of One-Dimensional Ultracold
Atoms.” Physical Review Research, vol. 8, 013297, American Physical Society,
2026, doi:10.1103/rdsn-stlq.
short: A. Becker, G. Koutentakis, P. Schmelcher, Physical Review Research 8 (2026).
corr_author: '1'
date_created: 2026-04-05T22:01:32Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-07T09:37:57Z
day: '18'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1103/rdsn-stlq
external_id:
arxiv:
- '2512.15260'
file:
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file_name: 2026_PhysicalReviewResearch_Becker.pdf
file_size: 2131627
relation: main_file
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file_date_updated: 2026-04-07T09:34:31Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 7c040762-9f16-11ee-852c-dd79eeee4ab3
grant_number: F100403
name: Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions
publication: Physical Review Research
publication_identifier:
issn:
- 2643-1564
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Two-body Kapitza-Dirac scattering of one-dimensional ultracold atoms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21661'
abstract:
- lang: eng
text: Model checking undiscounted reachability and expected-reward properties on
Markov decision processes (MDPs) are key for the verification of systems that
act under uncertainty. Popular algorithms are policy iteration and variants of
value iteration; in tool competitions, most participants rely on the latter. These
algorithms generally need worst-case exponential time. However, the problem can
equally be formulated as a linear programme, solvable in polynomial time. In this
paper, we give a detailed overview of today’s state-of-the-art algorithms for
MDP model checking with a focus on performance and correctness. We highlight their
fundamental differences, and describe various optimizations and implementation
variants. We experimentally compare floating-point and exact-arithmetic implementations
of all algorithms on three benchmark sets using two probabilistic model checkers.
Our results show that (optimistic) value iteration is a sensible default, but
other algorithms are preferable in specific settings. This paper thereby provides
a guide for MDP verification practitioners—tool builders and users alike.
acknowledgement: "This research was funded by the European Union’s Horizon 2020 research
and innovation programme under Marie Skłodowska-Curie grant agreements 101008233
(MISSION)\r\nand 101034413 (IST-BRIDGE), by the Interreg North Sea project STORM_SAFE,
by a KI-Starter grant from the Ministerium für Kultur und Wissenschaft NRW, by NWO
VENI grant no. 639.021.754, and by NWO VIDI grant VI.Vidi.223.110 (TruSTy). Experiments
were performed with computing resources granted by RWTH Aachen University under
project rwth1632."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Arnd
full_name: Hartmanns, Arnd
last_name: Hartmanns
- first_name: Sebastian
full_name: Junges, Sebastian
last_name: Junges
- first_name: Tim
full_name: Quatmann, Tim
last_name: Quatmann
- first_name: Maximilian
full_name: Weininger, Maximilian
id: 02ab0197-cc70-11ed-ab61-918e71f56881
last_name: Weininger
orcid: 0000-0002-0163-2152
citation:
ama: Hartmanns A, Junges S, Quatmann T, Weininger M. The revised practitioner’s
guide to MDP model checking algorithms. International Journal on Software Tools
for Technology Transfer. 2026. doi:10.1007/s10009-026-00848-y
apa: Hartmanns, A., Junges, S., Quatmann, T., & Weininger, M. (2026). The revised
practitioner’s guide to MDP model checking algorithms. International Journal
on Software Tools for Technology Transfer. Springer Nature. https://doi.org/10.1007/s10009-026-00848-y
chicago: Hartmanns, Arnd, Sebastian Junges, Tim Quatmann, and Maximilian Weininger.
“The Revised Practitioner’s Guide to MDP Model Checking Algorithms.” International
Journal on Software Tools for Technology Transfer. Springer Nature, 2026.
https://doi.org/10.1007/s10009-026-00848-y.
ieee: A. Hartmanns, S. Junges, T. Quatmann, and M. Weininger, “The revised practitioner’s
guide to MDP model checking algorithms,” International Journal on Software
Tools for Technology Transfer. Springer Nature, 2026.
ista: Hartmanns A, Junges S, Quatmann T, Weininger M. 2026. The revised practitioner’s
guide to MDP model checking algorithms. International Journal on Software Tools
for Technology Transfer.
mla: Hartmanns, Arnd, et al. “The Revised Practitioner’s Guide to MDP Model Checking
Algorithms.” International Journal on Software Tools for Technology Transfer,
Springer Nature, 2026, doi:10.1007/s10009-026-00848-y.
short: A. Hartmanns, S. Junges, T. Quatmann, M. Weininger, International Journal
on Software Tools for Technology Transfer (2026).
date_created: 2026-04-05T22:01:32Z
date_published: 2026-03-09T00:00:00Z
date_updated: 2026-04-07T09:52:54Z
day: '09'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/s10009-026-00848-y
ec_funded: 1
has_accepted_license: '1'
keyword:
- Quantitative model checking
- Markov decision process
- Linear programming
- Value iteration
- Policy iteration
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s10009-026-00848-y
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: International Journal on Software Tools for Technology Transfer
publication_identifier:
eissn:
- 1433-2787
issn:
- 1433-2779
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '21668'
relation: software
status: public
scopus_import: '1'
status: public
title: The revised practitioner’s guide to MDP model checking algorithms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21699'
abstract:
- lang: eng
text: 'Recent research in nanophotonics for scintillation-based imaging has demonstrated
promising improvements in scintillator performance. In parallel, advances in nanophotonics
have enabled wavefront control through metasurfaces, a capability that has transformed
fields such as microscopy by allowing tailored control of optical propagation.
This naturally raises the following question, which we address in this perspective:
can wavefront-control strategies be leveraged to improve scintillation-based imaging?
To answer this question, we explore nanophotonic- and metasurface-enabled wavefront
control in scintillators to mitigate image blurring arising from their intrinsically
diffuse light emission. While depth-of-field extension in scintillation faces
fundamental limitations absent in microscopy, this approach reveals promising
avenues, including stacked scintillators, selective spatial-frequency enhancement,
and X-ray energy-dependent imaging. These results clarify the key distinctions
in adapting wavefront engineering to scintillation and its potential to enable
tailored detection strategies.'
article_number: '2601.09830'
article_processing_charge: No
arxiv: 1
author:
- first_name: Joshua
full_name: Chen, Joshua
last_name: Chen
- first_name: Sachin
full_name: Vaidya, Sachin
last_name: Vaidya
- first_name: Simo
full_name: Pajovic, Simo
last_name: Pajovic
- first_name: Seou
full_name: Choi, Seou
last_name: Choi
- first_name: William
full_name: Michaels, William
last_name: Michaels
- first_name: Louis Martin-Monier
full_name: Louis Martin-Monier, Louis Martin-Monier
last_name: Louis Martin-Monier
- first_name: Juejun
full_name: Hu, Juejun
last_name: Hu
- first_name: Carol
full_name: Cogswell, Carol
last_name: Cogswell
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: Marin
full_name: Soljačić, Marin
last_name: Soljačić
citation:
ama: Chen J, Vaidya S, Pajovic S, et al. Wavefront engineering for scintillation-based
imaging. arXiv. doi:10.48550/arXiv.2601.09830
apa: Chen, J., Vaidya, S., Pajovic, S., Choi, S., Michaels, W., Louis Martin-Monier,
L. M.-M., … Soljačić, M. (n.d.). Wavefront engineering for scintillation-based
imaging. arXiv. https://doi.org/10.48550/arXiv.2601.09830
chicago: Chen, Joshua, Sachin Vaidya, Simo Pajovic, Seou Choi, William Michaels,
Louis Martin-Monier Louis Martin-Monier, Juejun Hu, Carol Cogswell, Charles Roques-Carmes,
and Marin Soljačić. “Wavefront Engineering for Scintillation-Based Imaging.” ArXiv,
n.d. https://doi.org/10.48550/arXiv.2601.09830.
ieee: J. Chen et al., “Wavefront engineering for scintillation-based imaging,”
arXiv. .
ista: Chen J, Vaidya S, Pajovic S, Choi S, Michaels W, Louis Martin-Monier LM-M,
Hu J, Cogswell C, Roques-Carmes C, Soljačić M. Wavefront engineering for scintillation-based
imaging. arXiv, 2601.09830.
mla: Chen, Joshua, et al. “Wavefront Engineering for Scintillation-Based Imaging.”
ArXiv, 2601.09830, doi:10.48550/arXiv.2601.09830.
short: J. Chen, S. Vaidya, S. Pajovic, S. Choi, W. Michaels, L.M.-M. Louis Martin-Monier,
J. Hu, C. Cogswell, C. Roques-Carmes, M. Soljačić, ArXiv (n.d.).
date_created: 2026-04-09T09:10:41Z
date_published: 2026-01-14T00:00:00Z
date_updated: 2026-04-13T11:26:08Z
day: '14'
doi: 10.48550/arXiv.2601.09830
extern: '1'
external_id:
arxiv:
- '2601.09830'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.2601.09830'
month: '01'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
scopus_import: '1'
status: public
title: Wavefront engineering for scintillation-based imaging
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...