---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19735'
abstract:
- lang: eng
  text: The males and females of the brine shrimp Artemia franciscana are highly dimorphic,
    and this dimorphism is associated with substantial sex-biased gene expression
    in heads and gonads. How these sex-specific patterns of expression are regulated
    at the molecular level is unknown. A. franciscana also has differentiated ZW sex
    chromosomes, with complete dosage compensation, but the molecular mechanism through
    which compensation is achieved is unknown. Here, we conducted CUT&TAG assays targeting
    7 post-translational histone modifications (H3K27me3, H3K9me2, H3K9me3, H3K36me3,
    H3K27ac, H3K4me3, and H4K16ac) in heads and gonads of A. franciscana, allowing
    us to divide the genome into 12 chromatin states. We further defined functional
    chromatin signatures for all genes, which were correlated with transcript level
    abundances. Differences in the occupancy of the profiled epigenetic marks between
    sexes were associated with differential gene expression between males and females.
    Finally, we found a significant enrichment of the permissive H4K16ac histone mark
    in the Z-specific region in both tissues of females but not males, supporting
    the role of this histone mark in mediating dosage compensation of the Z chromosome.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: We thank the Vicoso lab for their help in maintaining Artemia and
  for their valuable feedback and suggestions. We thank Marwan Elkrewi for his useful
  technical advice and discussions. We are also grateful to the Scientific Unit at
  ISTA Austria for computational resources and assistance. This work was supported
  by Austrian science fund (FWF) grants PAT8748323 and SFB F88-10 (as part of the
  SFB Meiosis consortium https://sfbmeiosis.org) to BV and Swedish Research Council
  (Vetenskapsrådet, grant number 2020-06424) to MSTA.
article_number: msaf085
article_processing_charge: Yes
article_type: original
author:
- first_name: Vincent K
  full_name: Bett, Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- first_name: Minerva S
  full_name: Trejo Arellano, Minerva S
  id: 2b681148-eed5-11eb-b81b-ae229e8620f8
  last_name: Trejo Arellano
  orcid: 0000-0002-1982-3475
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Bett VK, Trejo Arellano MS, Vicoso B. Chromatin landscape is associated with
    sex-biased expression and Drosophila-like dosage compensation of the Z chromosome
    in Artemia franciscana. <i>Molecular Biology and Evolution</i>. 2025;42(5). doi:<a
    href="https://doi.org/10.1093/molbev/msaf085">10.1093/molbev/msaf085</a>
  apa: Bett, V. K., Trejo Arellano, M. S., &#38; Vicoso, B. (2025). Chromatin landscape
    is associated with sex-biased expression and Drosophila-like dosage compensation
    of the Z chromosome in Artemia franciscana. <i>Molecular Biology and Evolution</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/molbev/msaf085">https://doi.org/10.1093/molbev/msaf085</a>
  chicago: Bett, Vincent K, Minerva S Trejo Arellano, and Beatriz Vicoso. “Chromatin
    Landscape Is Associated with Sex-Biased Expression and Drosophila-like Dosage
    Compensation of the Z Chromosome in Artemia Franciscana.” <i>Molecular Biology
    and Evolution</i>. Oxford University Press, 2025. <a href="https://doi.org/10.1093/molbev/msaf085">https://doi.org/10.1093/molbev/msaf085</a>.
  ieee: V. K. Bett, M. S. Trejo Arellano, and B. Vicoso, “Chromatin landscape is associated
    with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome
    in Artemia franciscana,” <i>Molecular Biology and Evolution</i>, vol. 42, no.
    5. Oxford University Press, 2025.
  ista: Bett VK, Trejo Arellano MS, Vicoso B. 2025. Chromatin landscape is associated
    with sex-biased expression and Drosophila-like dosage compensation of the Z chromosome
    in Artemia franciscana. Molecular Biology and Evolution. 42(5), msaf085.
  mla: Bett, Vincent K., et al. “Chromatin Landscape Is Associated with Sex-Biased
    Expression and Drosophila-like Dosage Compensation of the Z Chromosome in Artemia
    Franciscana.” <i>Molecular Biology and Evolution</i>, vol. 42, no. 5, msaf085,
    Oxford University Press, 2025, doi:<a href="https://doi.org/10.1093/molbev/msaf085">10.1093/molbev/msaf085</a>.
  short: V.K. Bett, M.S. Trejo Arellano, B. Vicoso, Molecular Biology and Evolution
    42 (2025).
corr_author: '1'
date_created: 2025-05-25T22:16:56Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2026-10-07T22:31:24Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
- _id: DaZi
doi: 10.1093/molbev/msaf085
external_id:
  isi:
  - '001483460200001'
  pmid:
  - '40202086'
file:
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fulldoi: https://doi.org/10.1093/molbev/msaf085
has_accepted_license: '1'
intvolume: '        42'
isi: 1
issue: '5'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 8ed82125-16d5-11f0-9cad-fbcae312235b
  grant_number: PAT 8748323
  name: Sex chromosomes in evolution and development
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publication: Molecular Biology and Evolution
publication_identifier:
  eissn:
  - 1537-1719
  issn:
  - 0737-4038
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/vkb25/Chromatin-landscape-in-Artemia-franciscana.git
  record:
  - id: '20449'
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    status: public
  - id: '20444'
    relation: dissertation_contains
    status: deleted
scopus_import: '1'
status: public
title: Chromatin landscape is associated with sex-biased expression and Drosophila-like
  dosage compensation of the Z chromosome in Artemia franciscana
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 42
year: '2025'
...
---
OA_place: publisher
_id: '20357'
acknowledged_ssus:
- _id: ScienComp
- _id: E-Lib
acknowledgement: "I would also like to acknowledge the Austrian Academy of Sciences
  for funding through the\r\nDOC Fellowship program (fellowship number 26917), the
  Grants Office at ISTA for their\r\nassistance with the application, and the Scientific
  Computing Unit for their support regarding\r\nhigh-performance computation.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Natalia
  full_name: Ruzickova, Natalia
  id: D2761128-D73D-11E9-A1BF-BA0DE6697425
  last_name: Ruzickova
citation:
  ama: Ruzickova N. Effect propagation in biological networks. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20357">10.15479/AT-ISTA-20357</a>
  apa: Ruzickova, N. (2025). <i>Effect propagation in biological networks</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20357">https://doi.org/10.15479/AT-ISTA-20357</a>
  chicago: Ruzickova, Natalia. “Effect Propagation in Biological Networks.” Institute
    of Science and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20357">https://doi.org/10.15479/AT-ISTA-20357</a>.
  ieee: N. Ruzickova, “Effect propagation in biological networks,” Institute of Science
    and Technology Austria, 2025.
  ista: Ruzickova N. 2025. Effect propagation in biological networks. Institute of
    Science and Technology Austria.
  mla: Ruzickova, Natalia. <i>Effect Propagation in Biological Networks</i>. Institute
    of Science and Technology Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20357">10.15479/AT-ISTA-20357</a>.
  short: N. Ruzickova, Effect Propagation in Biological Networks, Institute of Science
    and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-09-15T17:04:48Z
date_published: 2025-09-15T00:00:00Z
date_updated: 2026-10-02T10:15:31Z
day: '15'
ddc:
- '570'
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: GaTk
doi: 10.15479/AT-ISTA-20357
doi_confirm: '1'
file:
- access_level: closed
  checksum: 0582508d439b233497384f83a8307398
  content_type: application/x-zip-compressed
  creator: cchlebak
  date_created: 2026-08-07T10:57:05Z
  date_updated: 2026-09-15T22:30:02Z
  embargo_to: open_access
  file_id: '22661'
  file_name: 2025_Ruzickova_Natalia_Thesis.zip
  file_size: 56464803
  relation: source_file
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  checksum: b722289fd550abede63adc27b9c61784
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  creator: cchlebak
  date_created: 2026-08-07T10:57:34Z
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  file_id: '22662'
  file_name: 2025_Ruzickova_Natalia_Thesis.pdf
  file_size: 30634378
  relation: main_file
file_date_updated: 2026-09-15T22:30:02Z
fulldoi: https://doi.org/10.15479/AT-ISTA-20357
has_accepted_license: '1'
keyword:
- gene regulation
- networks
- omnigenic model
- pancreas
- collective behaviour
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '156'
project:
- _id: 7bec9174-9f16-11ee-852c-ded9fe5f810e
  name: Collective behaviour of cells in pancreatic Islets of Langerhans
publication_identifier:
  isbn:
  - 978-3-99078-066-4
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18525'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
title: Effect propagation in biological networks
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20563'
abstract:
- lang: eng
  text: "The theory of optimal transport provides an elegant and powerful description
    of many evolution\r\nequations as gradient flows. The primary objective of this
    thesis is to adapt and extend the\r\ntheory to deal with important equations that
    are not covered by the classical framework,\r\nspecifically boundary value problems
    and kinetic equations. Additionally, we establish new\r\nresults in periodic homogenization
    for discrete dynamical optimal transport and in quantization\r\nof measures.\r\nSection
    1.1 serves as an invitation to the classical theory of optimal transport, including
    the\r\nmain definitions and a selection of well-established theorems. Sections
    1.2-1.5 introduce the\r\nmain results of this thesis, outline the motivations,
    and review the current state of the art.\r\nIn Chapter 2, we consider the Fokker–Planck
    equation on a bounded set with positive Dirichlet\r\nboundary conditions. We construct
    a time-discrete scheme involving a modification of the\r\nWasserstein distance
    and, under weak assumptions, prove its convergence to a solution of this\r\nboundary
    value problem. In dimension 1, we show that this solution is a gradient flow in
    a\r\nsuitable space of measures.\r\nChapter 3 presents joint work with Giovanni
    Brigati and Jan Maas. We introduce a new theory\r\nof optimal transport to describe
    and study particle systems at the mesoscopic scale. We prove\r\nadapted versions
    of some fundamental theorems, including the Benamou–Brenier formula and\r\nthe
    identification of absolutely continuous curves of measures.\r\nChapter 4 presents
    joint work with Lorenzo Portinale. We prove convergence of dynamical\r\ntransportation
    functionals on periodic graphs in the large-scale limit when the cost functional\r\nis
    asymptotically linear. Additionally, we show that discrete 1-Wasserstein distances
    converge\r\nto 1-Wasserstein distances constructed from crystalline norms on R\r\nd\r\n.\r\nChapter
    5 concerns optimal empirical quantization: the problem of approximating a measure\r\nby
    the sum of n equally weighted Dirac deltas, so as to minimize the error in the
    p-Wasserstein\r\ndistance. Our main result is an analog of Zador’s theorem, providing
    asymptotic bounds for\r\nthe minimal error as n tends to infinity.\r\n"
acknowledgement: "The research contained in this thesis has received funding from
  the Austrian Science\r\nFund (FWF) project 10.55776/F65."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Filippo
  full_name: Quattrocchi, Filippo
  id: 3ebd6ba8-edfb-11eb-afb5-91a9745ba308
  last_name: Quattrocchi
  orcid: 0009-0000-9773-1931
citation:
  ama: Quattrocchi F. Optimal transport methods for kinetic equations, boundary value
    problems, and discretization of measures. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20563">10.15479/AT-ISTA-20563</a>
  apa: Quattrocchi, F. (2025). <i>Optimal transport methods for kinetic equations,
    boundary value problems, and discretization of measures</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20563">https://doi.org/10.15479/AT-ISTA-20563</a>
  chicago: Quattrocchi, Filippo. “Optimal Transport Methods for Kinetic Equations,
    Boundary Value Problems, and Discretization of Measures.” Institute of Science
    and Technology Austria, 2025. <a href="https://doi.org/10.15479/AT-ISTA-20563">https://doi.org/10.15479/AT-ISTA-20563</a>.
  ieee: F. Quattrocchi, “Optimal transport methods for kinetic equations, boundary
    value problems, and discretization of measures,” Institute of Science and Technology
    Austria, 2025.
  ista: Quattrocchi F. 2025. Optimal transport methods for kinetic equations, boundary
    value problems, and discretization of measures. Institute of Science and Technology
    Austria.
  mla: Quattrocchi, Filippo. <i>Optimal Transport Methods for Kinetic Equations, Boundary
    Value Problems, and Discretization of Measures</i>. Institute of Science and Technology
    Austria, 2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20563">10.15479/AT-ISTA-20563</a>.
  short: F. Quattrocchi, Optimal Transport Methods for Kinetic Equations, Boundary
    Value Problems, and Discretization of Measures, Institute of Science and Technology
    Austria, 2025.
corr_author: '1'
date_created: 2025-10-28T13:10:49Z
date_published: 2025-11-03T00:00:00Z
date_updated: 2026-10-02T11:24:55Z
day: '03'
ddc:
- '515'
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JaMa
doi: 10.15479/AT-ISTA-20563
file:
- access_level: open_access
  checksum: 6f55275bdf99992be3a6457d949dd664
  content_type: application/pdf
  creator: fquattro
  date_created: 2025-11-17T21:04:15Z
  date_updated: 2026-01-01T23:30:03Z
  embargo: 2026-01-01
  file_id: '20653'
  file_name: 2025_quattrocchi_filippo_thesis.pdf
  file_size: 4326411
  relation: main_file
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  creator: fquattro
  date_created: 2025-11-17T21:05:43Z
  date_updated: 2026-01-01T23:30:03Z
  embargo_to: open_access
  file_id: '20654'
  file_name: 2025_quattrocchi_thesis.zip
  file_size: 11726509
  relation: source_file
file_date_updated: 2026-01-01T23:30:03Z
fulldoi: https://doi.org/10.15479/AT-ISTA-20563
has_accepted_license: '1'
keyword:
- optimal transport
- kinetic equations
- boundary value problems
- quantization
- gradient flows
- homogenization
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: '240'
project:
- _id: 260482E2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: F06504
  name: Taming Complexity in Partial Differential Systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '20569'
    relation: part_of_dissertation
    status: public
  - id: '20571'
    relation: part_of_dissertation
    status: public
  - id: '20570'
    relation: part_of_dissertation
    status: public
  - id: '18706'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
title: Optimal transport methods for kinetic equations, boundary value problems, and
  discretization of measures
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20569'
abstract:
- lang: eng
  text: 'This is the first part of a general description in terms of mass transport
    for time-evolving interacting particles systems, at a mesoscopic level. Beyond
    kinetic theory, our framework naturally applies in biology, computer vision, and
    engineering. The central object of our study is a new discrepancy d between two
    probability distributions in position and velocity states, which is reminiscent
    of the 2-Wasserstein distance, but of second-order nature. We construct d in two
    steps. First, we optimise over transport plans. The cost function is given by
    the minimal acceleration between two coupled states on a fixed time horizon T.
    Second, we further optimise over the time horizon T > 0. We prove the existence
    of optimal transport plans and maps, and study two time-continuous characterisations
    of d. One is given in terms of dynamical transport plans. The other one -- in
    the spirit of the Benamou--Brenier formula -- is formulated as the minimisation
    of an action of the acceleration field, constrained by Vlasov''s equations. Equivalence
    of static and dynamical formulations of d holds true. While part of this result
    can be derived from recent, parallel developments in optimal control between measures,
    we give an original proof relying on two new ingredients: Galilean regularisation
    of Vlasov''s equations and a kinetic Monge--Mather shortening principle. Finally,
    we establish a first-order differential calculus in the geometry induced by d,
    and identify solutions to Vlasov''s equations with curves of measures satisfying
    a certain d-absolute continuity condition. One consequence is an explicit formula
    for the d-derivative of such curves.'
acknowledgement: "This work was partially inspired by an unpublished note from 2014
  by Guillaume Carlier,\r\nJean Dolbeault, and Bruno Nazaret. GB deeply thanks Jean
  Dolbeault for proposing\r\nthis problem to him, guiding him into the subject, and
  sharing the aforementioned note.\r\nWe are grateful to Karthik Elamvazhuthi for
  making us aware of the work [20].\r\nThe work of GB has received funding from the
  European Union’s Horizon 2020 research and innovation programme under the Marie
  Sklodowska-Curie grant agreement\r\nNo 101034413.\r\nJM and FQ gratefully acknowledge
  support from the Austrian Science Fund (FWF)\r\nproject 10.55776/F65."
article_number: '2502.15665'
article_processing_charge: No
arxiv: 1
author:
- first_name: Giovanni
  full_name: Brigati, Giovanni
  id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1
  last_name: Brigati
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
- first_name: Filippo
  full_name: Quattrocchi, Filippo
  id: 3ebd6ba8-edfb-11eb-afb5-91a9745ba308
  last_name: Quattrocchi
  orcid: 0009-0000-9773-1931
citation:
  ama: 'Brigati G, Maas J, Quattrocchi F. Kinetic Optimal Transport (OTIKIN) -- Part
    1: Second-order discrepancies between probability measures. <i>arXiv</i>. doi:<a
    href="https://doi.org/10.48550/arXiv.2502.15665">10.48550/arXiv.2502.15665</a>'
  apa: 'Brigati, G., Maas, J., &#38; Quattrocchi, F. (n.d.). Kinetic Optimal Transport
    (OTIKIN) -- Part 1: Second-order discrepancies between probability measures. <i>arXiv</i>.
    <a href="https://doi.org/10.48550/arXiv.2502.15665">https://doi.org/10.48550/arXiv.2502.15665</a>'
  chicago: 'Brigati, Giovanni, Jan Maas, and Filippo Quattrocchi. “Kinetic Optimal
    Transport (OTIKIN) -- Part 1: Second-Order Discrepancies between Probability Measures.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2502.15665">https://doi.org/10.48550/arXiv.2502.15665</a>.'
  ieee: 'G. Brigati, J. Maas, and F. Quattrocchi, “Kinetic Optimal Transport (OTIKIN)
    -- Part 1: Second-order discrepancies between probability measures,” <i>arXiv</i>.
    .'
  ista: 'Brigati G, Maas J, Quattrocchi F. Kinetic Optimal Transport (OTIKIN) -- Part
    1: Second-order discrepancies between probability measures. arXiv, 2502.15665.'
  mla: 'Brigati, Giovanni, et al. “Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-Order
    Discrepancies between Probability Measures.” <i>ArXiv</i>, 2502.15665, doi:<a
    href="https://doi.org/10.48550/arXiv.2502.15665">10.48550/arXiv.2502.15665</a>.'
  short: G. Brigati, J. Maas, F. Quattrocchi, ArXiv (n.d.).
corr_author: '1'
date_created: 2025-10-28T13:12:08Z
date_published: 2025-08-10T00:00:00Z
date_updated: 2026-10-07T22:31:31Z
day: '10'
department:
- _id: GradSch
- _id: JaMa
doi: 10.48550/arXiv.2502.15665
ec_funded: 1
external_id:
  arxiv:
  - '2502.15665'
fulldoi: https://doi.org/10.48550/arXiv.2502.15665
keyword:
- optimal transport
- kinetic theory
- second-order discrepancy
- Vlasov equation
- Wasserstein splines.
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2502.15665
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '20563'
    relation: dissertation_contains
    status: public
status: public
title: 'Kinetic Optimal Transport (OTIKIN) -- Part 1: Second-order discrepancies between
  probability measures'
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
_id: '20212'
abstract:
- lang: eng
  text: "Cortical development has been studied for many decades and with each passing
    year, we learn \r\nmore about the processes that govern the tightly regulated
    developmental program. Up until \r\nrecently, the field has struggled to gain
    reliable access to progenitors at the single-cell level, \r\nlimiting the resolution
    at which we can study cortical development in vivo. Therefore, much of \r\nthe
    data we have on mammalian cortical development is at the cell population level.
    The \r\nsubsequent pages of this thesis describe novel elements of cortical development
    in mice; \r\nacquired using a candidate gene approach in conjunction with Mosaic
    Analysis with Double \r\nMarkers (MADM) to achieve single cell resolution. In
    this thesis, I briefly provide an overview \r\nof the state of the field, describe
    the methodology used to quantify morphological \r\ncharacteristics of neurons
    and glia, and delve into the role of Phosphatase and tensin \r\nhomologue on chromosome
    ten (Pten) in neurogenesis and gliogenesis in the developing mouse \r\ncortex.
    By using MADM to generate genetic mosaics, in which only a small fraction of cells
    \r\nare mutated, to study population-level changes, we can bypass the early postnatal
    lethality \r\nreported in Pten conditional knockouts (cKOs) using Emx1-Cre. We
    used Emx1-CreERT2 to \r\ninduce clonal deletion of Pten, and quantify RGP neurogenic
    output at the single progenitor \r\nlevel. Pten-mutant neuron populations within
    the mosaics were significantly expanded. In the \r\nlatter parts of this thesis,
    we describe how Pten deletion leads to an increase in the abundance \r\nof astrocytes.
    We availed ourselves of the flexibility offered by the MADM system to generate
    \r\nPten mosaics within a series of distinct knockout tissues to test for the
    interactions between \r\nPten and a battery of genes involved in distinct pro-gliogenic
    signaling pathways. Our survey \r\nof Pten’s interactions with genes in key signaling
    pathways reveals that ERK1/2 are the critical \r\neffectors downstream of EGFR
    signaling essential for gliogenesis. Altogether, our results \r\ndemonstrate that
    Pten plays critical and distinct roles throughout cortical RGP lineage \r\nprogression. "
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: "I would also like to\r\nthank the Austrian Academy of Sciences for
  awarding me a 2-year DOC fellowship\r\n(DOC26253)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Osvaldo
  full_name: Miranda, Osvaldo
  id: 862A3C56-A8BF-11E9-B4FA-D9E3E5697425
  last_name: Miranda
  orcid: 0000-0001-6618-6889
citation:
  ama: Miranda O. Unraveling the role of Pten in cortical stem cell lineage progression
    using MADM. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20212">10.15479/AT-ISTA-20212</a>
  apa: Miranda, O. (2025). <i>Unraveling the role of Pten in cortical stem cell lineage
    progression using MADM</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-20212">https://doi.org/10.15479/AT-ISTA-20212</a>
  chicago: Miranda, Osvaldo. “Unraveling the Role of Pten in Cortical Stem Cell Lineage
    Progression Using MADM.” Institute of Science and Technology Austria, 2025. <a
    href="https://doi.org/10.15479/AT-ISTA-20212">https://doi.org/10.15479/AT-ISTA-20212</a>.
  ieee: O. Miranda, “Unraveling the role of Pten in cortical stem cell lineage progression
    using MADM,” Institute of Science and Technology Austria, 2025.
  ista: Miranda O. 2025. Unraveling the role of Pten in cortical stem cell lineage
    progression using MADM. Institute of Science and Technology Austria.
  mla: Miranda, Osvaldo. <i>Unraveling the Role of Pten in Cortical Stem Cell Lineage
    Progression Using MADM</i>. Institute of Science and Technology Austria, 2025,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-20212">10.15479/AT-ISTA-20212</a>.
  short: O. Miranda, Unraveling the Role of Pten in Cortical Stem Cell Lineage Progression
    Using MADM, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-22T14:07:00Z
date_published: 2025-08-22T00:00:00Z
date_updated: 2026-10-02T12:16:56Z
day: '22'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SiHi
doi: 10.15479/AT-ISTA-20212
doi_confirm: '1'
file:
- access_level: closed
  checksum: 3331f76bbef74ff4908e2d2c9262045c
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  creator: omiranda
  date_created: 2025-08-26T09:03:50Z
  date_updated: 2026-08-26T22:30:02Z
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  file_id: '20230'
  file_name: 2025_MirandaRomero_OsvaldoAntonio_Thesis.docx
  file_size: 32887334
  relation: source_file
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  date_created: 2025-08-26T09:05:55Z
  date_updated: 2026-08-26T22:30:02Z
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  relation: main_file
file_date_updated: 2026-08-26T22:30:02Z
fulldoi: https://doi.org/10.15479/AT-ISTA-20212
has_accepted_license: '1'
keyword:
- Pten
- mtor
- cortical development
- MADM
- Mapk
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '119'
project:
- _id: 34c9fbcb-11ca-11ed-8bc3-98fa5658610d
  grant_number: '26253'
  name: Molecular Mechanisms Regulating Cortical Neural Stem Cell Lineage Progression
    and Astrocyte Development
publication_identifier:
  isbn:
  - 978-3-99078-063-3
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17425'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
title: Unraveling the role of Pten in cortical stem cell lineage progression using
  MADM
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: publisher
_id: '20117'
abstract:
- lang: eng
  text: "Auxin is essential for many aspects of plant growth and development, from
    \r\nembryogenesis to organ senescence. Polar auxin transport leads to local auxin
    maxima and \r\ngradients, which are important for regulating various plant development
    process, including \r\nembryogenesis, organogenesis and vascular tissue formation.
    The polar auxin transport is \r\nmediated by auxin influx carrier AUX1/LAX proteins
    and efflux carrier PIN proteins. The \r\nregulation of PIN proteins is a key convergence
    of crosstalk between auxin and other \r\nhormones, such as cytokinin. Cytokinin
    promotes the degradation of PIN1 in Arabidopsis \r\nroots, preferentially the
    dephosphorylated PIN1, and the process is independent of \r\ntranscription and
    translation (Marhavý et al., 2011; Marhavý et al., 2014). The internalization
    \r\nof PIN proteins from plasma membrane is controlled by clathrin-mediated endocytosis
    \r\n(Dhonukshe et al., 2007; Kitakura et al., 2011). However, whether cytokinin
    affects the PIN1 \r\ndegradation through regulating the phosphorylation of PIN1
    or trafficking components is \r\nunknown. Here, we demonstrate that dynamin related
    protein DRP2s are required for the \r\ncytokinin regulated trafficking of PIN1
    and PIN2 in Arabidopsis root epidermal cells. Despite \r\nthe reported redundancy
    of DRP2A and DRP2B in gametophyte development, we found that \r\nCK-mediated PIN1
    degradation and –induced PIN2 membrane localization is affected in drp2a \r\nor
    drp2b single mutants. Interestingly, we found that cytokinin regulates the recruitment
    of \r\nDRP2A—but not DRP2B—to clathrin-coated pits, and affects the stability
    and plasma \r\nmembrane localization of DRP2A. Furthermore, we studied the involvement
    of cytokinin \r\nreceptors in the regulation of cytokinin on DRP2A. Additionally,
    the assembly and disassembly \r\ncycle of dynamin is mediated by its dephosphorylation
    and phosphotylation cycle; thus, we \r\ninvestigated the role of DRP2A phosphorylation
    in its cytokinin-regulated assembly and in \r\ncytokinin-regulated PIN trafficking.
    Altogether, we found that cytokinin regulated PIN \r\ntrafficking in Arabidopsis
    root epidermal cells involves modulation of the phosphorylation of \r\nendocytosis
    accessory protein DRP2A. "
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: "I would also like to acknowledge the invaluable assistance provided
  by the Plant\r\nFacility, Imaging & Optics Facility, and the Lab Support Facility.
  The technical support and\r\nresources offered by these facilities were indispensable
  to the successful completion of my\r\nexperiments."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Yiqun
  full_name: Wang, Yiqun
  id: 82F537F2-B517-11E9-84D7-6433E6697425
  last_name: Wang
citation:
  ama: Wang Y. The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development. 2025. doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>
  apa: Wang, Y. (2025). <i>The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>
  chicago: Wang, Yiqun. “The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development.” Institute of Science and Technology Austria, 2025.
    <a href="https://doi.org/10.15479/AT-ISTA-20117">https://doi.org/10.15479/AT-ISTA-20117</a>.
  ieee: Y. Wang, “The role of dynamin related protein 2A in cytokinin regulated plant
    growth and development,” Institute of Science and Technology Austria, 2025.
  ista: Wang Y. 2025. The role of dynamin related protein 2A in cytokinin regulated
    plant growth and development. Institute of Science and Technology Austria.
  mla: Wang, Yiqun. <i>The Role of Dynamin Related Protein 2A in Cytokinin Regulated
    Plant Growth and Development</i>. Institute of Science and Technology Austria,
    2025, doi:<a href="https://doi.org/10.15479/AT-ISTA-20117">10.15479/AT-ISTA-20117</a>.
  short: Y. Wang, The Role of Dynamin Related Protein 2A in Cytokinin Regulated Plant
    Growth and Development, Institute of Science and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-08-04T15:24:21Z
date_published: 2025-08-04T00:00:00Z
date_updated: 2026-10-02T12:33:36Z
day: '04'
ddc:
- '580'
degree_awarded: PhD
department:
- _id: GradSch
- _id: EvBe
doi: 10.15479/AT-ISTA-20117
doi_confirm: '1'
file:
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  creator: yiqwang
  date_created: 2025-08-22T08:22:10Z
  date_updated: 2026-09-03T22:30:03Z
  embargo_to: open_access
  file_id: '20209'
  file_name: 2025_Wang_Yiqun_Thesis.docx
  file_size: 25798848
  relation: source_file
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  content_type: application/pdf
  creator: yiqwang
  date_created: 2025-08-22T10:32:30Z
  date_updated: 2026-09-03T22:30:03Z
  embargo: 2026-09-03
  file_id: '20211'
  file_name: 2025_Wang_Yiqun_Thesis.pdf
  file_size: 12628313
  relation: main_file
file_date_updated: 2026-09-03T22:30:03Z
fulldoi: https://doi.org/10.15479/AT-ISTA-20117
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '108'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '18063'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
title: The role of dynamin related protein 2A in cytokinin regulated plant growth
  and development
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '22026'
abstract:
- lang: eng
  text: We address two pressing questions in the theory of the Korteweg–de Vries (KdV)
    equation. First, we show the uniqueness of solutions to KdV that are merely bounded,
    without any further decay, regularity, periodicity, or almost periodicity assumptions.
    The second question, emphasized by Deift, regards whether almost periodic initial
    data leads to almost periodic solutions to KdV. Building on the new observation
    that this is false for the Airy equation, we construct an example of almost periodic
    initial data whose KdV evolution remains bounded, but fails to be almost periodic
    at a later time. Our uniqueness result ensures that the solution constructed is
    the unique development of this initial data.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Andreia
  full_name: Chapouto, Andreia
  last_name: Chapouto
- first_name: Rowan
  full_name: Killip, Rowan
  last_name: Killip
- first_name: Monica
  full_name: Visan, Monica
  id: 056daca0-b8d1-11f0-964f-f91054abf8ca
  last_name: Visan
citation:
  ama: 'Chapouto A, Killip R, Vişan M. Bounded solutions of KdV: Uniqueness and the
    loss of almost periodicity. <i>Duke Mathematical Journal</i>. 2024;173(7):1227-1267.
    doi:<a href="https://doi.org/10.1215/00127094-2023-0035">10.1215/00127094-2023-0035</a>'
  apa: 'Chapouto, A., Killip, R., &#38; Vişan, M. (2024). Bounded solutions of KdV:
    Uniqueness and the loss of almost periodicity. <i>Duke Mathematical Journal</i>.
    Duke University Press. <a href="https://doi.org/10.1215/00127094-2023-0035">https://doi.org/10.1215/00127094-2023-0035</a>'
  chicago: 'Chapouto, Andreia, Rowan Killip, and Monica Vişan. “Bounded Solutions
    of KdV: Uniqueness and the Loss of Almost Periodicity.” <i>Duke Mathematical Journal</i>.
    Duke University Press, 2024. <a href="https://doi.org/10.1215/00127094-2023-0035">https://doi.org/10.1215/00127094-2023-0035</a>.'
  ieee: 'A. Chapouto, R. Killip, and M. Vişan, “Bounded solutions of KdV: Uniqueness
    and the loss of almost periodicity,” <i>Duke Mathematical Journal</i>, vol. 173,
    no. 7. Duke University Press, pp. 1227–1267, 2024.'
  ista: 'Chapouto A, Killip R, Vişan M. 2024. Bounded solutions of KdV: Uniqueness
    and the loss of almost periodicity. Duke Mathematical Journal. 173(7), 1227–1267.'
  mla: 'Chapouto, Andreia, et al. “Bounded Solutions of KdV: Uniqueness and the Loss
    of Almost Periodicity.” <i>Duke Mathematical Journal</i>, vol. 173, no. 7, Duke
    University Press, 2024, pp. 1227–67, doi:<a href="https://doi.org/10.1215/00127094-2023-0035">10.1215/00127094-2023-0035</a>.'
  short: A. Chapouto, R. Killip, M. Vişan, Duke Mathematical Journal 173 (2024) 1227–1267.
das_tickbox: '1'
date_created: 2026-06-19T07:34:05Z
date_published: 2024-05-15T00:00:00Z
date_updated: 2026-06-22T10:32:25Z
day: '15'
doi: 10.1215/00127094-2023-0035
extern: '1'
external_id:
  arxiv:
  - '2209.07501'
fulldoi: https://doi.org/10.1215/00127094-2023-0035
intvolume: '       173'
issue: '7'
keyword:
- Almost-periodic solutions
- Korteweg–de Vries
- unconditional uniqueness
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2209.07501
month: '05'
oa: 1
oa_version: Preprint
page: 1227-1267
publication: Duke Mathematical Journal
publication_identifier:
  issn:
  - 0012-7094
publication_status: published
publisher: Duke University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bounded solutions of KdV: Uniqueness and the loss of almost periodicity'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 173
year: '2024'
...
---
_id: '12178'
abstract:
- lang: eng
  text: In this paper we consider the stochastic primitive equation for geophysical
    flows subject to transport noise and turbulent pressure. Admitting very rough
    noise terms, the global existence and uniqueness of solutions to this stochastic
    partial differential equation are proven using stochastic maximal L² regularity,
    the theory of critical spaces for stochastic evolution equations, and global a
    priori bounds. Compared to other results in this direction, we do not need any
    smallness assumption on the transport noise which acts directly on the velocity
    field and we also allow rougher noise terms. The adaptation to Stratonovich type
    noise and, more generally, to variable viscosity and/or conductivity are discussed
    as well.
acknowledgement: The authors thank the anonymous referees for their helpful comments
  and suggestions. Open Access funding enabled and organized by Projekt DEAL.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Antonio
  full_name: Agresti, Antonio
  id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72
  last_name: Agresti
  orcid: 0000-0002-9573-2962
- first_name: Matthias
  full_name: Hieber, Matthias
  last_name: Hieber
- first_name: Amru
  full_name: Hussein, Amru
  last_name: Hussein
- first_name: Martin
  full_name: Saal, Martin
  last_name: Saal
citation:
  ama: 'Agresti A, Hieber M, Hussein A, Saal M. The stochastic primitive equations
    with transport noise and turbulent pressure. <i>Stochastics and Partial Differential
    Equations: Analysis and Computations</i>. 2024;12:53-133. doi:<a href="https://doi.org/10.1007/s40072-022-00277-3">10.1007/s40072-022-00277-3</a>'
  apa: 'Agresti, A., Hieber, M., Hussein, A., &#38; Saal, M. (2024). The stochastic
    primitive equations with transport noise and turbulent pressure. <i>Stochastics
    and Partial Differential Equations: Analysis and Computations</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s40072-022-00277-3">https://doi.org/10.1007/s40072-022-00277-3</a>'
  chicago: 'Agresti, Antonio, Matthias Hieber, Amru Hussein, and Martin Saal. “The
    Stochastic Primitive Equations with Transport Noise and Turbulent Pressure.” <i>Stochastics
    and Partial Differential Equations: Analysis and Computations</i>. Springer Nature,
    2024. <a href="https://doi.org/10.1007/s40072-022-00277-3">https://doi.org/10.1007/s40072-022-00277-3</a>.'
  ieee: 'A. Agresti, M. Hieber, A. Hussein, and M. Saal, “The stochastic primitive
    equations with transport noise and turbulent pressure,” <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>, vol. 12. Springer Nature,
    pp. 53–133, 2024.'
  ista: 'Agresti A, Hieber M, Hussein A, Saal M. 2024. The stochastic primitive equations
    with transport noise and turbulent pressure. Stochastics and Partial Differential
    Equations: Analysis and Computations. 12, 53–133.'
  mla: 'Agresti, Antonio, et al. “The Stochastic Primitive Equations with Transport
    Noise and Turbulent Pressure.” <i>Stochastics and Partial Differential Equations:
    Analysis and Computations</i>, vol. 12, Springer Nature, 2024, pp. 53–133, doi:<a
    href="https://doi.org/10.1007/s40072-022-00277-3">10.1007/s40072-022-00277-3</a>.'
  short: 'A. Agresti, M. Hieber, A. Hussein, M. Saal, Stochastics and Partial Differential
    Equations: Analysis and Computations 12 (2024) 53–133.'
date_created: 2023-01-12T12:12:29Z
date_published: 2024-03-01T00:00:00Z
date_updated: 2024-07-22T09:30:40Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s40072-022-00277-3
external_id:
  arxiv:
  - '2109.09561'
  isi:
  - '000874389000001'
file:
- access_level: open_access
  checksum: 59c9000761134d681bdf9d482664044c
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-22T09:29:48Z
  date_updated: 2024-07-22T09:29:48Z
  file_id: '17297'
  file_name: 2024_StochasticsEquations_Agresti.pdf
  file_size: 1206413
  relation: main_file
  success: 1
file_date_updated: 2024-07-22T09:29:48Z
fulldoi: https://doi.org/10.1007/s40072-022-00277-3
has_accepted_license: '1'
intvolume: '        12'
isi: 1
keyword:
- Applied Mathematics
- Modeling and Simulation
- Statistics and Probability
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 53-133
publication: 'Stochastics and Partial Differential Equations: Analysis and Computations'
publication_identifier:
  eissn:
  - 2194-041X
  issn:
  - 2194-0401
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The stochastic primitive equations with transport noise and turbulent pressure
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2024'
...
---
_id: '12485'
abstract:
- lang: eng
  text: In this paper we introduce the critical variational setting for parabolic
    stochastic evolution equations of quasi- or semi-linear type. Our results improve
    many of the abstract results in the classical variational setting. In particular,
    we are able to replace the usual weak or local monotonicity condition by a more
    flexible local Lipschitz condition. Moreover, the usual growth conditions on the
    multiplicative noise are weakened considerably. Our new setting provides general
    conditions under which local and global existence and uniqueness hold. Moreover,
    we prove continuous dependence on the initial data. We show that many classical
    SPDEs, which could not be covered by the classical variational setting, do fit
    in the critical variational setting. In particular, this is the case for the Cahn-Hilliard
    equations, tamed Navier-Stokes equations, and Allen-Cahn equation.
acknowledgement: The first author has received funding from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (grant agreement No 948819) . The second author is supported by the VICI subsidy
  VI.C.212.027 of the Netherlands Organisation for Scientific Research (NWO).
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Antonio
  full_name: Agresti, Antonio
  id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72
  last_name: Agresti
  orcid: 0000-0002-9573-2962
- first_name: Mark
  full_name: Veraar, Mark
  last_name: Veraar
citation:
  ama: Agresti A, Veraar M. The critical variational setting for stochastic evolution
    equations. <i>Probability Theory and Related Fields</i>. 2024;188:957-1015. doi:<a
    href="https://doi.org/10.1007/s00440-023-01249-x">10.1007/s00440-023-01249-x</a>
  apa: Agresti, A., &#38; Veraar, M. (2024). The critical variational setting for
    stochastic evolution equations. <i>Probability Theory and Related Fields</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00440-023-01249-x">https://doi.org/10.1007/s00440-023-01249-x</a>
  chicago: Agresti, Antonio, and Mark Veraar. “The Critical Variational Setting for
    Stochastic Evolution Equations.” <i>Probability Theory and Related Fields</i>.
    Springer Nature, 2024. <a href="https://doi.org/10.1007/s00440-023-01249-x">https://doi.org/10.1007/s00440-023-01249-x</a>.
  ieee: A. Agresti and M. Veraar, “The critical variational setting for stochastic
    evolution equations,” <i>Probability Theory and Related Fields</i>, vol. 188.
    Springer Nature, pp. 957–1015, 2024.
  ista: Agresti A, Veraar M. 2024. The critical variational setting for stochastic
    evolution equations. Probability Theory and Related Fields. 188, 957–1015.
  mla: Agresti, Antonio, and Mark Veraar. “The Critical Variational Setting for Stochastic
    Evolution Equations.” <i>Probability Theory and Related Fields</i>, vol. 188,
    Springer Nature, 2024, pp. 957–1015, doi:<a href="https://doi.org/10.1007/s00440-023-01249-x">10.1007/s00440-023-01249-x</a>.
  short: A. Agresti, M. Veraar, Probability Theory and Related Fields 188 (2024) 957–1015.
date_created: 2023-02-02T10:45:15Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-09-04T11:27:46Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s00440-023-01249-x
ec_funded: 1
external_id:
  arxiv:
  - '2206.00230'
  isi:
  - '001154226500001'
file:
- access_level: open_access
  checksum: b8572339dbc5b8de4934dc5fd34afc7d
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  creator: dernst
  date_created: 2024-07-22T09:21:09Z
  date_updated: 2024-07-22T09:21:09Z
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file_date_updated: 2024-07-22T09:21:09Z
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intvolume: '       188'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 957-1015
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
  call_identifier: H2020
  grant_number: '948819'
  name: Bridging Scales in Random Materials
publication: Probability Theory and Related Fields
publication_identifier:
  eissn:
  - 1432-2064
  issn:
  - 0178-8051
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The critical variational setting for stochastic evolution equations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 188
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '12486'
abstract:
- lang: eng
  text: This paper is concerned with the problem of regularization by noise of systems
    of reaction–diffusion equations with mass control. It is known that strong solutions
    to such systems of PDEs may blow-up in finite time. Moreover, for many systems
    of practical interest, establishing whether the blow-up occurs or not is an open
    question. Here we prove that a suitable multiplicative noise of transport type
    has a regularizing effect. More precisely, for both a sufficiently noise intensity
    and a high spectrum, the blow-up of strong solutions is delayed up to an arbitrary
    large time. Global existence is shown for the case of exponentially decreasing
    mass. The proofs combine and extend recent developments in regularization by noise
    and in the Lp(Lq)-approach to stochastic PDEs, highlighting new connections between
    the two areas.
acknowledgement: "The author has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (Grant Agreement No. 948819).\r\nThe author thanks Lorenzo Dello Schiavo, Lucio
  Galeati and Mark Veraar for helpful comments. The author acknowledges Caterina Balzotti
  for her support in creating the picture. The author\r\nthanks the anonymous referee
  for helpful comments. "
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Antonio
  full_name: Agresti, Antonio
  id: 673cd0cc-9b9a-11eb-b144-88f30e1fbb72
  last_name: Agresti
  orcid: 0000-0002-9573-2962
citation:
  ama: 'Agresti A. Delayed blow-up and enhanced diffusion by transport noise for systems
    of reaction-diffusion equations. <i>Stochastics and Partial Differential Equations:
    Analysis and Computations</i>. 2024;12:1907-1981. doi:<a href="https://doi.org/10.1007/s40072-023-00319-4">10.1007/s40072-023-00319-4</a>'
  apa: 'Agresti, A. (2024). Delayed blow-up and enhanced diffusion by transport noise
    for systems of reaction-diffusion equations. <i>Stochastics and Partial Differential
    Equations: Analysis and Computations</i>. Springer Nature. <a href="https://doi.org/10.1007/s40072-023-00319-4">https://doi.org/10.1007/s40072-023-00319-4</a>'
  chicago: 'Agresti, Antonio. “Delayed Blow-up and Enhanced Diffusion by Transport
    Noise for Systems of Reaction-Diffusion Equations.” <i>Stochastics and Partial
    Differential Equations: Analysis and Computations</i>. Springer Nature, 2024.
    <a href="https://doi.org/10.1007/s40072-023-00319-4">https://doi.org/10.1007/s40072-023-00319-4</a>.'
  ieee: 'A. Agresti, “Delayed blow-up and enhanced diffusion by transport noise for
    systems of reaction-diffusion equations,” <i>Stochastics and Partial Differential
    Equations: Analysis and Computations</i>, vol. 12. Springer Nature, pp. 1907–1981,
    2024.'
  ista: 'Agresti A. 2024. Delayed blow-up and enhanced diffusion by transport noise
    for systems of reaction-diffusion equations. Stochastics and Partial Differential
    Equations: Analysis and Computations. 12, 1907–1981.'
  mla: 'Agresti, Antonio. “Delayed Blow-up and Enhanced Diffusion by Transport Noise
    for Systems of Reaction-Diffusion Equations.” <i>Stochastics and Partial Differential
    Equations: Analysis and Computations</i>, vol. 12, Springer Nature, 2024, pp.
    1907–81, doi:<a href="https://doi.org/10.1007/s40072-023-00319-4">10.1007/s40072-023-00319-4</a>.'
  short: 'A. Agresti, Stochastics and Partial Differential Equations: Analysis and
    Computations 12 (2024) 1907–1981.'
corr_author: '1'
date_created: 2023-02-02T10:45:47Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-08-05T13:23:09Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s40072-023-00319-4
ec_funded: 1
external_id:
  arxiv:
  - '2207.08293'
  isi:
  - '001108594600001'
  pmid:
  - '39104877'
file:
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  date_created: 2025-01-09T08:01:02Z
  date_updated: 2025-01-09T08:01:02Z
  file_id: '18787'
  file_name: 2024_StochPartDiffEquations_Agresti.pdf
  file_size: 1320682
  relation: main_file
  success: 1
file_date_updated: 2025-01-09T08:01:02Z
fulldoi: https://doi.org/10.1007/s40072-023-00319-4
has_accepted_license: '1'
intvolume: '        12'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1907-1981
pmid: 1
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
  call_identifier: H2020
  grant_number: '948819'
  name: Bridging Scales in Random Materials
publication: 'Stochastics and Partial Differential Equations: Analysis and Computations'
publication_identifier:
  eissn:
  - 2194-041X
  issn:
  - 2194-0401
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Delayed blow-up and enhanced diffusion by transport noise for systems of reaction-diffusion
  equations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '12738'
abstract:
- lang: eng
  text: We study turn-based stochastic zero-sum games with lexicographic preferences
    over objectives. Stochastic games are standard models in control, verification,
    and synthesis of stochastic reactive systems that exhibit both randomness as well
    as controllable and adversarial non-determinism. Lexicographic order allows one
    to consider multiple objectives with a strict preference order. To the best of
    our knowledge, stochastic games with lexicographic objectives have not been studied
    before. For a mixture of reachability and safety objectives, we show that deterministic
    lexicographically optimal strategies exist and memory is only required to remember
    the already satisfied and violated objectives. For a constant number of objectives,
    we show that the relevant decision problem is in NP∩coNP, matching the current
    known bound for single objectives; and in general the decision problem is PSPACE-hard
    and can be solved in NEXPTIME∩coNEXPTIME. We present an algorithm that computes
    the lexicographically optimal strategies via a reduction to the computation of
    optimal strategies in a sequence of single-objectives games. For omega-regular
    objectives, we restrict our analysis to one-player games, also known as Markov
    decision processes. We show that lexicographically optimal strategies exist and
    need either randomization or finite memory. We present an algorithm that solves
    the relevant decision problem in polynomial time. We have implemented our algorithms
    and report experimental results on various case studies.
acknowledgement: Tobias Winkler and Joost-Pieter Katoen are supported by the DFG RTG
  2236 UnRAVeL and the innovation programme under the Marie Skłodowska-Curie grant
  agreement No. 101008233 (Mission). Krishnendu Chatterjee is supported by the ERC
  CoG 863818 (ForM-SMArt) and the Vienna Science and Technology Fund (WWTF) Project
  ICT15-003. Maximilian Weininger is supported by the DFG projects 383882557 Statistical
  Unbounded Verification (SUV) and 427755713 Group-By Objectives in Probabilistic
  Verification (GOPro). Stefanie Mohr is supported by the DFG RTG 2428 CONVEY. Open
  Access funding enabled and organized by Projekt DEAL.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Joost P
  full_name: Katoen, Joost P
  id: 4524F760-F248-11E8-B48F-1D18A9856A87
  last_name: Katoen
  orcid: 0000-0002-6143-1926
- first_name: Stefanie
  full_name: Mohr, Stefanie
  last_name: Mohr
- first_name: Maximilian
  full_name: Weininger, Maximilian
  last_name: Weininger
- first_name: Tobias
  full_name: Winkler, Tobias
  last_name: Winkler
citation:
  ama: Chatterjee K, Katoen JP, Mohr S, Weininger M, Winkler T. Stochastic games with
    lexicographic objectives. <i>Formal Methods in System Design</i>. 2024;63:40-80.
    doi:<a href="https://doi.org/10.1007/s10703-023-00411-4">10.1007/s10703-023-00411-4</a>
  apa: Chatterjee, K., Katoen, J. P., Mohr, S., Weininger, M., &#38; Winkler, T. (2024).
    Stochastic games with lexicographic objectives. <i>Formal Methods in System Design</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s10703-023-00411-4">https://doi.org/10.1007/s10703-023-00411-4</a>
  chicago: Chatterjee, Krishnendu, Joost P Katoen, Stefanie Mohr, Maximilian Weininger,
    and Tobias Winkler. “Stochastic Games with Lexicographic Objectives.” <i>Formal
    Methods in System Design</i>. Springer Nature, 2024. <a href="https://doi.org/10.1007/s10703-023-00411-4">https://doi.org/10.1007/s10703-023-00411-4</a>.
  ieee: K. Chatterjee, J. P. Katoen, S. Mohr, M. Weininger, and T. Winkler, “Stochastic
    games with lexicographic objectives,” <i>Formal Methods in System Design</i>,
    vol. 63. Springer Nature, pp. 40–80, 2024.
  ista: Chatterjee K, Katoen JP, Mohr S, Weininger M, Winkler T. 2024. Stochastic
    games with lexicographic objectives. Formal Methods in System Design. 63, 40–80.
  mla: Chatterjee, Krishnendu, et al. “Stochastic Games with Lexicographic Objectives.”
    <i>Formal Methods in System Design</i>, vol. 63, Springer Nature, 2024, pp. 40–80,
    doi:<a href="https://doi.org/10.1007/s10703-023-00411-4">10.1007/s10703-023-00411-4</a>.
  short: K. Chatterjee, J.P. Katoen, S. Mohr, M. Weininger, T. Winkler, Formal Methods
    in System Design 63 (2024) 40–80.
date_created: 2023-03-19T23:00:59Z
date_published: 2024-10-01T00:00:00Z
date_updated: 2026-04-16T09:31:13Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/s10703-023-00411-4
ec_funded: 1
external_id:
  isi:
  - '000946174300001'
file:
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  checksum: 111e76b76163640a2c89237642af586f
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  creator: dernst
  date_created: 2025-01-09T07:31:31Z
  date_updated: 2025-01-09T07:31:31Z
  file_id: '18781'
  file_name: 2024_FromMethodsSys_Chatterjee.pdf
  file_size: 2614190
  relation: main_file
  success: 1
file_date_updated: 2025-01-09T07:31:31Z
fulldoi: https://doi.org/10.1007/s10703-023-00411-4
has_accepted_license: '1'
intvolume: '        63'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 40-80
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication: Formal Methods in System Design
publication_identifier:
  eissn:
  - 1572-8102
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
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    status: public
scopus_import: '1'
status: public
title: Stochastic games with lexicographic objectives
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 63
year: '2024'
...
---
_id: '12875'
abstract:
- lang: eng
  text: The superior colliculus (SC) in the mammalian midbrain is essential for multisensory
    integration and is composed of a rich diversity of excitatory and inhibitory neurons
    and glia. However, the developmental principles directing the generation of SC
    cell-type diversity are not understood. Here, we pursued systematic cell lineage
    tracing in silico and in vivo, preserving full spatial information, using genetic
    mosaic analysis with double markers (MADM)-based clonal analysis with single-cell
    sequencing (MADM-CloneSeq). The analysis of clonally related cell lineages revealed
    that radial glial progenitors (RGPs) in SC are exceptionally multipotent. Individual
    resident RGPs have the capacity to produce all excitatory and inhibitory SC neuron
    types, even at the stage of terminal division. While individual clonal units show
    no pre-defined cellular composition, the establishment of appropriate relative
    proportions of distinct neuronal types occurs in a PTEN-dependent manner. Collectively,
    our findings provide an inaugural framework at the single-RGP/-cell level of the
    mammalian SC ontogeny.
acknowledged_ssus:
- _id: Bio
- _id: M-Shop
- _id: LifeSc
- _id: PreCl
acknowledgement: "We thank Liqun Luo for his continued support, for providing essential
  resources for generating Fzd10-CreER mice which were generated in his laboratory,
  and for comments on the manuscript; W. Zhong for providing Nestin-Cre transgenic
  mouse line for this study; A. Heger for mouse colony management; R. Beattie and
  T. Asenov for designing and producing components of acute slice recovery chamber
  for MADM-CloneSeq experiments; and K. Leopold, J. Rodarte and N. Amberg for initial
  experiments, technical support and/or assistance. This study was supported by the
  Scientific Service Units (SSU) of IST Austria through resources provided by the
  Imaging & Optics Facility (IOF), Laboratory Support Facility (LSF), Miba Machine
  Shop, and Pre-clinical Facility (PCF). G.C. received funding from European Commission
  (IST plus postdoctoral fellowship). This work was supported by ISTA institutional\r\nfunds;
  the Austrian Science Fund Special Research Programmes (FWF SFB F78 Neuro Stem Modulation)
  to S.H. "
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Giselle T
  full_name: Cheung, Giselle T
  id: 471195F6-F248-11E8-B48F-1D18A9856A87
  last_name: Cheung
  orcid: 0000-0001-8457-2572
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Peter
  full_name: Koppensteiner, Peter
  id: 3B8B25A8-F248-11E8-B48F-1D18A9856A87
  last_name: Koppensteiner
  orcid: 0000-0002-3509-1948
- first_name: Thomas
  full_name: Krausgruber, Thomas
  last_name: Krausgruber
- first_name: Carmen
  full_name: Streicher, Carmen
  id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
  last_name: Streicher
- first_name: Martin
  full_name: Schrammel, Martin
  id: f13e7cae-e8bd-11ed-841a-96dedf69f46d
  last_name: Schrammel
- first_name: Natalie Y
  full_name: Özgen, Natalie Y
  id: e68ece33-f6e0-11ea-865d-ae1031dcc090
  last_name: Özgen
- first_name: Alexis
  full_name: Ivec, Alexis
  id: 1d144691-e8be-11ed-9b33-bdd3077fad4c
  last_name: Ivec
- first_name: Christoph
  full_name: Bock, Christoph
  last_name: Bock
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Cheung GT, Pauler F, Koppensteiner P, et al. Multipotent progenitors instruct
    ontogeny of the superior colliculus. <i>Neuron</i>. 2024;112(2):230-246.e11. doi:<a
    href="https://doi.org/10.1016/j.neuron.2023.11.009">10.1016/j.neuron.2023.11.009</a>
  apa: Cheung, G. T., Pauler, F., Koppensteiner, P., Krausgruber, T., Streicher, C.,
    Schrammel, M., … Hippenmeyer, S. (2024). Multipotent progenitors instruct ontogeny
    of the superior colliculus. <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2023.11.009">https://doi.org/10.1016/j.neuron.2023.11.009</a>
  chicago: Cheung, Giselle T, Florian Pauler, Peter Koppensteiner, Thomas Krausgruber,
    Carmen Streicher, Martin Schrammel, Natalie Y Özgen, et al. “Multipotent Progenitors
    Instruct Ontogeny of the Superior Colliculus.” <i>Neuron</i>. Elsevier, 2024.
    <a href="https://doi.org/10.1016/j.neuron.2023.11.009">https://doi.org/10.1016/j.neuron.2023.11.009</a>.
  ieee: G. T. Cheung <i>et al.</i>, “Multipotent progenitors instruct ontogeny of
    the superior colliculus,” <i>Neuron</i>, vol. 112, no. 2. Elsevier, p. 230–246.e11,
    2024.
  ista: Cheung GT, Pauler F, Koppensteiner P, Krausgruber T, Streicher C, Schrammel
    M, Özgen NY, Ivec A, Bock C, Shigemoto R, Hippenmeyer S. 2024. Multipotent progenitors
    instruct ontogeny of the superior colliculus. Neuron. 112(2), 230–246.e11.
  mla: Cheung, Giselle T., et al. “Multipotent Progenitors Instruct Ontogeny of the
    Superior Colliculus.” <i>Neuron</i>, vol. 112, no. 2, Elsevier, 2024, p. 230–246.e11,
    doi:<a href="https://doi.org/10.1016/j.neuron.2023.11.009">10.1016/j.neuron.2023.11.009</a>.
  short: G.T. Cheung, F. Pauler, P. Koppensteiner, T. Krausgruber, C. Streicher, M.
    Schrammel, N.Y. Özgen, A. Ivec, C. Bock, R. Shigemoto, S. Hippenmeyer, Neuron
    112 (2024) 230–246.e11.
corr_author: '1'
date_created: 2023-04-27T09:41:48Z
date_published: 2024-01-17T00:00:00Z
date_updated: 2025-12-30T10:54:12Z
day: '17'
ddc:
- '570'
department:
- _id: SiHi
- _id: RySh
doi: 10.1016/j.neuron.2023.11.009
external_id:
  isi:
  - '001163937900001'
  pmid:
  - '38096816'
file:
- access_level: open_access
  checksum: 32b3788f7085cf44a84108d8faaff3ce
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-06T13:56:15Z
  date_updated: 2024-02-06T13:56:15Z
  file_id: '14944'
  file_name: 2024_Neuron_Cheung.pdf
  file_size: 5942467
  relation: main_file
  success: 1
file_date_updated: 2024-02-06T13:56:15Z
fulldoi: https://doi.org/10.1016/j.neuron.2023.11.009
has_accepted_license: '1'
intvolume: '       112'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 230-246.e11
pmid: 1
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F7805
  name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
    Mechanisms of Neural Stem Cell Lineage Progression
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA Website
    relation: press_release
    url: https://ista.ac.at/en/news/the-pedigree-of-brain-cells/
scopus_import: '1'
status: public
title: Multipotent progenitors instruct ontogeny of the superior colliculus
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2024'
...
---
_id: '13093'
abstract:
- lang: eng
  text: The direct, solid state, and reversible conversion between heat and electricity
    using thermoelectric devices finds numerous potential uses, especially around
    room temperature. However, the relatively high material processing cost limits
    their real applications. Silver selenide (Ag2Se) is one of the very few n-type
    thermoelectric (TE) materials for room-temperature applications. Herein, we report
    a room temperature, fast, and aqueous-phase synthesis approach to produce Ag2Se,
    which can be extended to other metal chalcogenides. These materials reach TE figures
    of merit (zT) of up to 0.76 at 380 K. To improve these values, bismuth sulfide
    (Bi2S3) particles also prepared in an aqueous solution are incorporated into the
    Ag2Se matrix. In this way, a series of Ag2Se/Bi2S3 composites with Bi2S3 wt %
    of 0.5, 1.0, and 1.5 are prepared by solution blending and hot-press sintering.
    The presence of Bi2S3 significantly improves the Seebeck coefficient and power
    factor while at the same time decreasing the thermal conductivity with no apparent
    drop in electrical conductivity. Thus, a maximum zT value of 0.96 is achieved
    in the composites with 1.0 wt % Bi2S3 at 370 K. Furthermore, a high average zT
    value (zTave) of 0.93 in the 300–390 K range is demonstrated.
acknowledgement: 'Open Access is funded by the Austrian Science Fund (FWF). B.N.,
  M.L., Y.Z., K.X., and X.H. thank the China Scholarship Council (CSC) for the scholarship
  support. C.C. received funding from the FWF “Lise Meitner Fellowship” grant agreement
  M 2889-N. M.I. acknowledges the financial support from ISTA and the Werner Siemens
  Foundation. ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457
  and project NANOGEN (PID2020-116093RB-C43) funded by MCIN/AEI/10.13039/501100011033/.
  ICN2 was supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.:
  CEX2021-001214-S) and was funded by the CERCA Programme/Generalitat de Catalunya.
  J.L. is a Serra Húnter Fellow and is grateful to the ICREA Academia program and
  projects MICINN/FEDER PID2021-124572OB-C31 and 2021 SGR 01061. K.H.L. acknowledges
  support from the National Natural Science Foundation of China (22208293). This study
  is part of the Advanced Materials programme and was supported by MCIN with funding
  from European Union NextGenerationEU (PRTR-C17.I1) and by Generalitat de Catalunya.'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Bingfei
  full_name: Nan, Bingfei
  last_name: 'Nan'
- first_name: Mengyao
  full_name: Li, Mengyao
  last_name: Li
- first_name: Yu
  full_name: Zhang, Yu
  last_name: Zhang
- first_name: Ke
  full_name: Xiao, Ke
  last_name: Xiao
- first_name: Khak Ho
  full_name: Lim, Khak Ho
  last_name: Lim
- first_name: Cheng
  full_name: Chang, Cheng
  id: 9E331C2E-9F27-11E9-AE48-5033E6697425
  last_name: Chang
  orcid: 0000-0002-9515-4277
- first_name: Xu
  full_name: Han, Xu
  last_name: Han
- first_name: Yong
  full_name: Zuo, Yong
  last_name: Zuo
- first_name: Junshan
  full_name: Li, Junshan
  last_name: Li
- first_name: Jordi
  full_name: Arbiol, Jordi
  last_name: Arbiol
- first_name: Jordi
  full_name: Llorca, Jordi
  last_name: Llorca
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Andreu
  full_name: Cabot, Andreu
  last_name: Cabot
citation:
  ama: Nan B, Li M, Zhang Y, et al. Engineering of thermoelectric composites based
    on silver selenide in aqueous solution and ambient temperature. <i>ACS Applied
    Electronic Materials</i>. 2024;6(5):2807-215. doi:<a href="https://doi.org/10.1021/acsaelm.3c00055">10.1021/acsaelm.3c00055</a>
  apa: Nan, B., Li, M., Zhang, Y., Xiao, K., Lim, K. H., Chang, C., … Cabot, A. (2024).
    Engineering of thermoelectric composites based on silver selenide in aqueous solution
    and ambient temperature. <i>ACS Applied Electronic Materials</i>. American Chemical
    Society. <a href="https://doi.org/10.1021/acsaelm.3c00055">https://doi.org/10.1021/acsaelm.3c00055</a>
  chicago: Nan, Bingfei, Mengyao Li, Yu Zhang, Ke Xiao, Khak Ho Lim, Cheng Chang,
    Xu Han, et al. “Engineering of Thermoelectric Composites Based on Silver Selenide
    in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic Materials</i>.
    American Chemical Society, 2024. <a href="https://doi.org/10.1021/acsaelm.3c00055">https://doi.org/10.1021/acsaelm.3c00055</a>.
  ieee: B. Nan <i>et al.</i>, “Engineering of thermoelectric composites based on silver
    selenide in aqueous solution and ambient temperature,” <i>ACS Applied Electronic
    Materials</i>, vol. 6, no. 5. American Chemical Society, pp. 2807–215, 2024.
  ista: Nan B, Li M, Zhang Y, Xiao K, Lim KH, Chang C, Han X, Zuo Y, Li J, Arbiol
    J, Llorca J, Ibáñez M, Cabot A. 2024. Engineering of thermoelectric composites
    based on silver selenide in aqueous solution and ambient temperature. ACS Applied
    Electronic Materials. 6(5), 2807–215.
  mla: Nan, Bingfei, et al. “Engineering of Thermoelectric Composites Based on Silver
    Selenide in Aqueous Solution and Ambient Temperature.” <i>ACS Applied Electronic
    Materials</i>, vol. 6, no. 5, American Chemical Society, 2024, pp. 2807–215, doi:<a
    href="https://doi.org/10.1021/acsaelm.3c00055">10.1021/acsaelm.3c00055</a>.
  short: B. Nan, M. Li, Y. Zhang, K. Xiao, K.H. Lim, C. Chang, X. Han, Y. Zuo, J.
    Li, J. Arbiol, J. Llorca, M. Ibáñez, A. Cabot, ACS Applied Electronic Materials
    6 (2024) 2807–215.
date_created: 2023-05-28T22:01:03Z
date_published: 2024-05-28T00:00:00Z
date_updated: 2025-04-14T09:29:33Z
day: '28'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1021/acsaelm.3c00055
external_id:
  isi:
  - '000986859000001'
  pmid:
  - '38828037'
file:
- access_level: open_access
  checksum: 1f743eaf4fc988cd30102b7c2f12c15d
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-16T07:54:21Z
  date_updated: 2024-07-16T07:54:21Z
  file_id: '17250'
  file_name: 2024_ACSAppElecMaterials_Nan.pdf
  file_size: 5851865
  relation: main_file
  success: 1
file_date_updated: 2024-07-16T07:54:21Z
fulldoi: https://doi.org/10.1021/acsaelm.3c00055
has_accepted_license: '1'
intvolume: '         6'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 2807-215
pmid: 1
project:
- _id: 9B8804FC-BA93-11EA-9121-9846C619BF3A
  grant_number: M02889
  name: Bottom-up Engineering for Thermoelectric Applications
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: ACS Applied Electronic Materials
publication_identifier:
  eissn:
  - 2637-6113
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Engineering of thermoelectric composites based on silver selenide in aqueous
  solution and ambient temperature
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '13129'
abstract:
- lang: eng
  text: "We study the representative volume element (RVE) method, which is a method
    to approximately infer the effective behavior ahom of a stationary random medium.
    The latter is described by a coefficient field a(x) generated from a given ensemble
    ⟨⋅⟩ and the corresponding linear elliptic operator −∇⋅a∇. In line with the theory
    of homogenization, the method proceeds by computing d=3 correctors (d denoting
    the space dimension). To be numerically tractable, this computation has to be
    done on a finite domain: the so-called representative volume element, i.e., a
    large box with, say, periodic boundary conditions. The main message of this article
    is: Periodize the ensemble instead of its realizations. By this, we mean that
    it is better to sample from a suitably periodized ensemble than to periodically
    extend the restriction of a realization a(x) from the whole-space ensemble ⟨⋅⟩.
    We make this point by investigating the bias (or systematic error), i.e., the
    difference between ahom and the expected value of the RVE method, in terms of
    its scaling w.r.t. the lateral size L of the box. In case of periodizing a(x),
    we heuristically argue that this error is generically O(L−1). In case of a suitable
    periodization of ⟨⋅⟩\r\n, we rigorously show that it is O(L−d). In fact, we give
    a characterization of the leading-order error term for both strategies and argue
    that even in the isotropic case it is generically non-degenerate. We carry out
    the rigorous analysis in the convenient setting of ensembles ⟨⋅⟩\r\n of Gaussian
    type, which allow for a straightforward periodization, passing via the (integrable)
    covariance function. This setting has also the advantage of making the Price theorem
    and the Malliavin calculus available for optimal stochastic estimates of correctors.
    We actually need control of second-order correctors to capture the leading-order
    error term. This is due to inversion symmetry when applying the two-scale expansion
    to the Green function. As a bonus, we present a stream-lined strategy to estimate
    the error in a higher-order two-scale expansion of the Green function."
acknowledgement: Open access funding provided by Institute of Science and Technology
  (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Nicolas
  full_name: Clozeau, Nicolas
  id: fea1b376-906f-11eb-847d-b2c0cf46455b
  last_name: Clozeau
- first_name: Marc
  full_name: Josien, Marc
  last_name: Josien
- first_name: Felix
  full_name: Otto, Felix
  last_name: Otto
- first_name: Qiang
  full_name: Xu, Qiang
  last_name: Xu
citation:
  ama: 'Clozeau N, Josien M, Otto F, Xu Q. Bias in the representative volume element
    method: Periodize the ensemble instead of its realizations. <i>Foundations of
    Computational Mathematics</i>. 2024;24:1305-1387. doi:<a href="https://doi.org/10.1007/s10208-023-09613-y">10.1007/s10208-023-09613-y</a>'
  apa: 'Clozeau, N., Josien, M., Otto, F., &#38; Xu, Q. (2024). Bias in the representative
    volume element method: Periodize the ensemble instead of its realizations. <i>Foundations
    of Computational Mathematics</i>. Springer Nature. <a href="https://doi.org/10.1007/s10208-023-09613-y">https://doi.org/10.1007/s10208-023-09613-y</a>'
  chicago: 'Clozeau, Nicolas, Marc Josien, Felix Otto, and Qiang Xu. “Bias in the
    Representative Volume Element Method: Periodize the Ensemble Instead of Its Realizations.”
    <i>Foundations of Computational Mathematics</i>. Springer Nature, 2024. <a href="https://doi.org/10.1007/s10208-023-09613-y">https://doi.org/10.1007/s10208-023-09613-y</a>.'
  ieee: 'N. Clozeau, M. Josien, F. Otto, and Q. Xu, “Bias in the representative volume
    element method: Periodize the ensemble instead of its realizations,” <i>Foundations
    of Computational Mathematics</i>, vol. 24. Springer Nature, pp. 1305–1387, 2024.'
  ista: 'Clozeau N, Josien M, Otto F, Xu Q. 2024. Bias in the representative volume
    element method: Periodize the ensemble instead of its realizations. Foundations
    of Computational Mathematics. 24, 1305–1387.'
  mla: 'Clozeau, Nicolas, et al. “Bias in the Representative Volume Element Method:
    Periodize the Ensemble Instead of Its Realizations.” <i>Foundations of Computational
    Mathematics</i>, vol. 24, Springer Nature, 2024, pp. 1305–87, doi:<a href="https://doi.org/10.1007/s10208-023-09613-y">10.1007/s10208-023-09613-y</a>.'
  short: N. Clozeau, M. Josien, F. Otto, Q. Xu, Foundations of Computational Mathematics
    24 (2024) 1305–1387.
corr_author: '1'
date_created: 2023-06-11T22:00:40Z
date_published: 2024-08-01T00:00:00Z
date_updated: 2025-01-09T07:37:50Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s10208-023-09613-y
external_id:
  isi:
  - '000999623100001'
file:
- access_level: open_access
  checksum: ec0582e2b55e2703a7da2686ae0d682e
  content_type: application/pdf
  creator: dernst
  date_created: 2025-01-09T07:36:57Z
  date_updated: 2025-01-09T07:36:57Z
  file_id: '18782'
  file_name: 2024_FoundCompMath_Clozeau.pdf
  file_size: 1454406
  relation: main_file
  success: 1
file_date_updated: 2025-01-09T07:36:57Z
fulldoi: https://doi.org/10.1007/s10208-023-09613-y
has_accepted_license: '1'
intvolume: '        24'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 1305-1387
publication: Foundations of Computational Mathematics
publication_identifier:
  eissn:
  - 1615-3383
  issn:
  - 1615-3375
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bias in the representative volume element method: Periodize the ensemble instead
  of its realizations'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '20838'
abstract:
- lang: eng
  text: "For any 1 ≤ r ≤ ∞, we show that every diffeomorphism of a manifold of the
    form\r\nR/Z × M is a total renormalization of a Cr-close to identity map. In other
    words, for\r\nevery diffeomorphism f of R/Z×M, there exists a map g arbitrarily
    close to identity\r\nsuch that the first return map of g to a domain is conjugate
    to f and moreover the\r\norbit of this domain is equal to R/Z×M. This enables
    us to localize near the identity\r\nthe existence of many properties in dynamical
    systems, such as being Bernoulli for a\r\nsmooth volume form."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Pierre
  full_name: Berger, Pierre
  last_name: Berger
- first_name: Nicolaz
  full_name: Gourmelon, Nicolaz
  last_name: Gourmelon
- first_name: Mathieu
  full_name: Helfter, Mathieu
  id: 7d296fbe-e2c6-11ee-84d3-d5c2945f9a57
  last_name: Helfter
citation:
  ama: Berger P, Gourmelon N, Helfter M. Every diffeomorphism is a total renormalization
    of a close to identity map. <i>Inventiones mathematicae</i>. 2024;239(2):431-468.
    doi:<a href="https://doi.org/10.1007/s00222-024-01305-w">10.1007/s00222-024-01305-w</a>
  apa: Berger, P., Gourmelon, N., &#38; Helfter, M. (2024). Every diffeomorphism is
    a total renormalization of a close to identity map. <i>Inventiones Mathematicae</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00222-024-01305-w">https://doi.org/10.1007/s00222-024-01305-w</a>
  chicago: Berger, Pierre, Nicolaz Gourmelon, and Mathieu Helfter. “Every Diffeomorphism
    Is a Total Renormalization of a Close to Identity Map.” <i>Inventiones Mathematicae</i>.
    Springer Nature, 2024. <a href="https://doi.org/10.1007/s00222-024-01305-w">https://doi.org/10.1007/s00222-024-01305-w</a>.
  ieee: P. Berger, N. Gourmelon, and M. Helfter, “Every diffeomorphism is a total
    renormalization of a close to identity map,” <i>Inventiones mathematicae</i>,
    vol. 239, no. 2. Springer Nature, pp. 431–468, 2024.
  ista: Berger P, Gourmelon N, Helfter M. 2024. Every diffeomorphism is a total renormalization
    of a close to identity map. Inventiones mathematicae. 239(2), 431–468.
  mla: Berger, Pierre, et al. “Every Diffeomorphism Is a Total Renormalization of
    a Close to Identity Map.” <i>Inventiones Mathematicae</i>, vol. 239, no. 2, Springer
    Nature, 2024, pp. 431–68, doi:<a href="https://doi.org/10.1007/s00222-024-01305-w">10.1007/s00222-024-01305-w</a>.
  short: P. Berger, N. Gourmelon, M. Helfter, Inventiones Mathematicae 239 (2024)
    431–468.
date_created: 2025-12-19T10:15:13Z
date_published: 2024-12-19T00:00:00Z
date_updated: 2025-12-29T12:03:10Z
day: '19'
doi: 10.1007/s00222-024-01305-w
extern: '1'
external_id:
  arxiv:
  - '2210.09064'
fulldoi: https://doi.org/10.1007/s00222-024-01305-w
intvolume: '       239'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2210.09064
month: '12'
oa: 1
oa_version: Preprint
page: 431-468
publication: Inventiones mathematicae
publication_identifier:
  eissn:
  - 1432-1297
  issn:
  - 0020-9910
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Every diffeomorphism is a total renormalization of a close to identity map
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 239
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20961'
abstract:
- lang: eng
  text: Self-replicating molecules and well-defined folded macromolecules are of great
    significance in the emergence and evolution of life. How they may interconnect
    and affect each other remains largely elusive. Here, we demonstrate an abiotic
    system where a single building block can oligomerize to yield either a self-replicating
    molecule or a foldamer. Specifically, agitation of a disulfide-based dynamic combinatorial
    library at moderately elevated pH channels it selectively into a self-replicating
    hexamer assembled into fibers, after passing through a period where a 15-subunit
    macrocyclic foldamer existed transiently. Without mechanoagitation or at lower
    pH, the formation of hexamer fiber is suppressed, resulting in the accumulation
    of the 15mer foldamer. Foldamer and self-replicator can be interconverted in response
    to external stimuli, including agitation and a change in pH. Furthermore, upon
    the addition of a photoacid, the pH of the medium can be controlled by irradiation,
    driving the switching between replicator and foldamer and allowing a dissipative
    out-of-equilibrium state to be accessed, using light as a source of energy.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Yulong
  full_name: Jin, Yulong
  last_name: Jin
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: Juntian
  full_name: Wu, Juntian
  last_name: Wu
- first_name: Armin
  full_name: Kiani, Armin
  last_name: Kiani
- first_name: Rui
  full_name: Zhao, Rui
  last_name: Zhao
- first_name: Ivan
  full_name: Huc, Ivan
  last_name: Huc
- first_name: Sijbren
  full_name: Otto, Sijbren
  last_name: Otto
citation:
  ama: Jin Y, Mandal PK, Wu J, et al. Light-mediated interconversion between a foldamer
    and a self-replicator. <i>Journal of the American Chemical Society</i>. 2024;146(49):33395-33402.
    doi:<a href="https://doi.org/10.1021/jacs.4c09114">10.1021/jacs.4c09114</a>
  apa: Jin, Y., Mandal, P. K., Wu, J., Kiani, A., Zhao, R., Huc, I., &#38; Otto, S.
    (2024). Light-mediated interconversion between a foldamer and a self-replicator.
    <i>Journal of the American Chemical Society</i>. American Chemical Society. <a
    href="https://doi.org/10.1021/jacs.4c09114">https://doi.org/10.1021/jacs.4c09114</a>
  chicago: Jin, Yulong, Pradeep K Mandal, Juntian Wu, Armin Kiani, Rui Zhao, Ivan
    Huc, and Sijbren Otto. “Light-Mediated Interconversion between a Foldamer and
    a Self-Replicator.” <i>Journal of the American Chemical Society</i>. American
    Chemical Society, 2024. <a href="https://doi.org/10.1021/jacs.4c09114">https://doi.org/10.1021/jacs.4c09114</a>.
  ieee: Y. Jin <i>et al.</i>, “Light-mediated interconversion between a foldamer and
    a self-replicator,” <i>Journal of the American Chemical Society</i>, vol. 146,
    no. 49. American Chemical Society, pp. 33395–33402, 2024.
  ista: Jin Y, Mandal PK, Wu J, Kiani A, Zhao R, Huc I, Otto S. 2024. Light-mediated
    interconversion between a foldamer and a self-replicator. Journal of the American
    Chemical Society. 146(49), 33395–33402.
  mla: Jin, Yulong, et al. “Light-Mediated Interconversion between a Foldamer and
    a Self-Replicator.” <i>Journal of the American Chemical Society</i>, vol. 146,
    no. 49, American Chemical Society, 2024, pp. 33395–402, doi:<a href="https://doi.org/10.1021/jacs.4c09114">10.1021/jacs.4c09114</a>.
  short: Y. Jin, P.K. Mandal, J. Wu, A. Kiani, R. Zhao, I. Huc, S. Otto, Journal of
    the American Chemical Society 146 (2024) 33395–33402.
date_created: 2026-01-08T07:05:57Z
date_published: 2024-11-26T00:00:00Z
date_updated: 2026-01-19T11:03:31Z
day: '26'
ddc:
- '540'
doi: 10.1021/jacs.4c09114
extern: '1'
external_id:
  pmid:
  - '39590511'
fulldoi: https://doi.org/10.1021/jacs.4c09114
has_accepted_license: '1'
intvolume: '       146'
issue: '49'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1021/jacs.4c09114
month: '11'
oa: 1
oa_version: Published Version
page: 33395-33402
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
  eissn:
  - 1520-5126
  issn:
  - 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Light-mediated interconversion between a foldamer and a self-replicator
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 146
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20962'
abstract:
- lang: eng
  text: Systems chemistry has emerged as a useful paradigm to access structures and
    phenomena typically exhibited by living systems, including complex molecular systems
    such as self-replicators and foldamers. As we progress further toward the noncovalent
    synthesis of life-like systems, and eventually life itself, it is necessary to
    gain control over assembly pathways. Dissipative chemical fueling has enabled
    access to stable populations of (self-assembled) structures that would normally
    form only transiently. Here, we report a synthetic dynamic combinatorial library,
    made from a single structurally simple building block, from which a self-replicator
    and a foldamer can emerge along two distinct and competing pathways through an
    inter- or intramolecular assembly process, respectively. A fueled chemical reaction
    cycle is then set up to generate the foldamer transiently, in the presence of
    the self-replicator. The partitioning of the building block between the folding
    and self-replication pathways and the duration of the fueled reaction cycles are
    controlled by adjusting the amount of the chemical fuel. An out-of-equilibrium
    steady state involving the two assemblies could also be achieved by using a continuous
    stirred tank reactor with inflow and outflow of material. This work connects the
    domains of folding and self-replication in synthetic systems through dissipative
    out-of-equilibrium chemistry. It demonstrates that foldamers and self-replicators,
    formed from the same building block, can stably coexist if the system is continuously
    supplied with energy, while at equilibrium, the Gibbs phase rule prohibits such
    coexistence.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Ankush
  full_name: Sood, Ankush
  last_name: Sood
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: Jim
  full_name: Ottelé, Jim
  last_name: Ottelé
- first_name: Juntian
  full_name: Wu, Juntian
  last_name: Wu
- first_name: Marcel
  full_name: Eleveld, Marcel
  last_name: Eleveld
- first_name: Joydev
  full_name: Hatai, Joydev
  last_name: Hatai
- first_name: Charalampos G.
  full_name: Pappas, Charalampos G.
  last_name: Pappas
- first_name: Ivan
  full_name: Huc, Ivan
  last_name: Huc
- first_name: Sijbren
  full_name: Otto, Sijbren
  last_name: Otto
citation:
  ama: Sood A, Mandal PK, Ottelé J, et al. Simultaneous formation of a foldamer and
    a self-replicator by out-of-equilibrium dynamic covalent chemistry. <i>Journal
    of the American Chemical Society</i>. 2024;146(49):33386-33394. doi:<a href="https://doi.org/10.1021/jacs.4c09111">10.1021/jacs.4c09111</a>
  apa: Sood, A., Mandal, P. K., Ottelé, J., Wu, J., Eleveld, M., Hatai, J., … Otto,
    S. (2024). Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium
    dynamic covalent chemistry. <i>Journal of the American Chemical Society</i>. American
    Chemical Society. <a href="https://doi.org/10.1021/jacs.4c09111">https://doi.org/10.1021/jacs.4c09111</a>
  chicago: Sood, Ankush, Pradeep K Mandal, Jim Ottelé, Juntian Wu, Marcel Eleveld,
    Joydev Hatai, Charalampos G. Pappas, Ivan Huc, and Sijbren Otto. “Simultaneous
    Formation of a Foldamer and a Self-Replicator by out-of-Equilibrium Dynamic Covalent
    Chemistry.” <i>Journal of the American Chemical Society</i>. American Chemical
    Society, 2024. <a href="https://doi.org/10.1021/jacs.4c09111">https://doi.org/10.1021/jacs.4c09111</a>.
  ieee: A. Sood <i>et al.</i>, “Simultaneous formation of a foldamer and a self-replicator
    by out-of-equilibrium dynamic covalent chemistry,” <i>Journal of the American
    Chemical Society</i>, vol. 146, no. 49. American Chemical Society, pp. 33386–33394,
    2024.
  ista: Sood A, Mandal PK, Ottelé J, Wu J, Eleveld M, Hatai J, Pappas CG, Huc I, Otto
    S. 2024. Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium
    dynamic covalent chemistry. Journal of the American Chemical Society. 146(49),
    33386–33394.
  mla: Sood, Ankush, et al. “Simultaneous Formation of a Foldamer and a Self-Replicator
    by out-of-Equilibrium Dynamic Covalent Chemistry.” <i>Journal of the American
    Chemical Society</i>, vol. 146, no. 49, American Chemical Society, 2024, pp. 33386–94,
    doi:<a href="https://doi.org/10.1021/jacs.4c09111">10.1021/jacs.4c09111</a>.
  short: A. Sood, P.K. Mandal, J. Ottelé, J. Wu, M. Eleveld, J. Hatai, C.G. Pappas,
    I. Huc, S. Otto, Journal of the American Chemical Society 146 (2024) 33386–33394.
date_created: 2026-01-08T07:06:27Z
date_published: 2024-11-26T00:00:00Z
date_updated: 2026-01-19T10:57:53Z
day: '26'
doi: 10.1021/jacs.4c09111
extern: '1'
external_id:
  pmid:
  - '39590110'
fulldoi: https://doi.org/10.1021/jacs.4c09111
has_accepted_license: '1'
intvolume: '       146'
issue: '49'
keyword:
- Fibers
- Foldamers
- Macrocycles
- Monomers
- Peptides
- Proteins
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1021/jacs.4c09111
month: '11'
oa: 1
oa_version: Published Version
page: 33386-33394
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
  eissn:
  - 1520-5126
  issn:
  - 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simultaneous formation of a foldamer and a self-replicator by out-of-equilibrium
  dynamic covalent chemistry
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 146
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20967'
abstract:
- lang: eng
  text: A biotinylated helical aromatic oligoamide foldamer equivalent in size to
    a 24mer peptide was designed without any prejudice other than to display various
    polar and hydrophobic side chains at its surface. It was synthesized on solid
    phase, its P- and M-helical conformers were separated by HPLC on a chiral stationary
    phase, and the solid state structure of a non-biotinylated analogue was elucidated
    by X-ray crystallography. Pull-down experiments from a yeast cell lysate using
    the foldamer as a bait followed by proteomic analysis revealed potential protein
    binding partners. Three of these proteins were recombinantly expressed. Biolayer
    interferometry showed submicromolar binding demonstrating the potential of a given
    foldamer to have affinity for certain proteins in the absence of design considerations.
    Yet, binding selectivity was low in all three cases since both P- and M-conformers
    bound to the proteins with similar affinities.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Sunbum
  full_name: Kwon, Sunbum
  last_name: Kwon
- first_name: Vasily
  full_name: Morozov, Vasily
  last_name: Morozov
- first_name: Lingfei
  full_name: Wang, Lingfei
  last_name: Wang
- first_name: Pradeep K
  full_name: Mandal, Pradeep K
  id: 6a3def15-d4b4-11ef-9fa9-a24c1f545ec3
  last_name: Mandal
  orcid: 0000-0001-5996-956X
- first_name: Stéphane
  full_name: Chaignepain, Stéphane
  last_name: Chaignepain
- first_name: Céline
  full_name: Douat, Céline
  last_name: Douat
- first_name: Ivan
  full_name: Huc, Ivan
  last_name: Huc
citation:
  ama: Kwon S, Morozov V, Wang L, et al. Interrogating the potential of helical aromatic
    foldamers for protein recognition. <i>Organic &#38; Biomolecular Chemistry</i>.
    2024;22(48):9342-9347. doi:<a href="https://doi.org/10.1039/d4ob01436g">10.1039/d4ob01436g</a>
  apa: Kwon, S., Morozov, V., Wang, L., Mandal, P. K., Chaignepain, S., Douat, C.,
    &#38; Huc, I. (2024). Interrogating the potential of helical aromatic foldamers
    for protein recognition. <i>Organic &#38; Biomolecular Chemistry</i>. Royal Society
    of Chemistry. <a href="https://doi.org/10.1039/d4ob01436g">https://doi.org/10.1039/d4ob01436g</a>
  chicago: Kwon, Sunbum, Vasily Morozov, Lingfei Wang, Pradeep K Mandal, Stéphane
    Chaignepain, Céline Douat, and Ivan Huc. “Interrogating the Potential of Helical
    Aromatic Foldamers for Protein Recognition.” <i>Organic &#38; Biomolecular Chemistry</i>.
    Royal Society of Chemistry, 2024. <a href="https://doi.org/10.1039/d4ob01436g">https://doi.org/10.1039/d4ob01436g</a>.
  ieee: S. Kwon <i>et al.</i>, “Interrogating the potential of helical aromatic foldamers
    for protein recognition,” <i>Organic &#38; Biomolecular Chemistry</i>, vol. 22,
    no. 48. Royal Society of Chemistry, pp. 9342–9347, 2024.
  ista: Kwon S, Morozov V, Wang L, Mandal PK, Chaignepain S, Douat C, Huc I. 2024.
    Interrogating the potential of helical aromatic foldamers for protein recognition.
    Organic &#38; Biomolecular Chemistry. 22(48), 9342–9347.
  mla: Kwon, Sunbum, et al. “Interrogating the Potential of Helical Aromatic Foldamers
    for Protein Recognition.” <i>Organic &#38; Biomolecular Chemistry</i>, vol. 22,
    no. 48, Royal Society of Chemistry, 2024, pp. 9342–47, doi:<a href="https://doi.org/10.1039/d4ob01436g">10.1039/d4ob01436g</a>.
  short: S. Kwon, V. Morozov, L. Wang, P.K. Mandal, S. Chaignepain, C. Douat, I. Huc,
    Organic &#38; Biomolecular Chemistry 22 (2024) 9342–9347.
date_created: 2026-01-11T14:32:23Z
date_published: 2024-10-30T00:00:00Z
date_updated: 2026-01-20T06:56:44Z
day: '30'
doi: 10.1039/d4ob01436g
extern: '1'
external_id:
  pmid:
  - '39501876'
fulldoi: https://doi.org/10.1039/d4ob01436g
has_accepted_license: '1'
intvolume: '        22'
issue: '48'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1039/D4OB01436G
month: '10'
oa: 1
oa_version: Published Version
page: 9342-9347
pmid: 1
publication: Organic & Biomolecular Chemistry
publication_identifier:
  eissn:
  - 1477-0539
  issn:
  - 1477-0520
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interrogating the potential of helical aromatic foldamers for protein recognition
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
  name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
  short: CC BY (3.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21064'
abstract:
- lang: eng
  text: The James Webb Space Telescope (JWST) is revolutionizing our knowledge of
    z > 5 galaxies and their actively accreting black holes. Using the JWST Cycle
    1 Treasury program Ultradeep NIRSpec and NIRCam Observations before the Epoch
    of Reionization (UNCOVER) in the lensing field A2744, we report the identification
    of a sample of little red dots at 3 < zphot < 7 that likely contain highly reddened
    accreting supermassive black holes. Using a NIRCam-only selection to F444W < 27.7
    mag, we find 26 sources over the ∼45 arcmin^2 field that are blue in F115W − F200W
    ∼ 0 (or βUV ∼ –2.0 for fλ ∝ λ^β), red in F200W − F444W = 1−4 (βopt ∼ +2.0), and
    are dominated by a point-source-like central component. Of the 20 sources with
    deep Atacama Large Millimeter/submillimeter Array (ALMA) 1.2 mm coverage, none
    are detected individually or in a stack. For the majority of the sample, spectral
    energy distribution fits to the JWST+ALMA observations prefer models with hot
    dust rather than obscured star formation to reproduce the red NIRCam colors and
    ALMA 1.2 mm nondetections. While compact dusty star formation cannot be ruled
    out, the combination of extremely small sizes (〈re〉 ≈ 50 pc after correction for
    magnification), red rest-frame optical slopes, and hot dust can be explained by
    reddened broad-line active galactic nuclei (AGNs). Our targets have faint M1450
    ≈ −14 to −18 mag but inferred bolometric luminosities of Lbol = 10^43–10^46 erg
    s^−1, reflecting their obscured nature. If the candidates are confirmed as AGNs
    with upcoming UNCOVER spectroscopy, then we have found an abundant population
    of reddened luminous AGNs that are at least ten times more numerous than UV-luminous
    AGNs at the same intrinsic bolometric luminosity.
acknowledgement: 'I.L. acknowledges support from Australian Research Council Future
  Fellowship FT220100798. J.E.G. and A.D.G acknowledge support from NSF/AAG grant
  #1007094, and J.E.G. also acknowledges support from NSF/AAG grant #1007052. L.J.F.
  and A.Z. acknowledge support by Grant No. 2020750 from the United States–Israel
  Binational Science Foundation (BSF) and grant No. 2109066 from the United States
  National Science Foundation (NSF), and by the Ministry of Science & Technology of
  Israel. The Cosmic Dawn Center is funded by the Danish National Research Foundation
  (DNRF) under grant #140. This work has received funding from the Swiss State Secretariat
  for Education, Research and Innovation (SERI) under contract number MB22.00072,
  as well as from the Swiss National Science Foundation (SNSF) through project grant
  200020_207349. P.D. acknowledges support from the NWO grant 016.VIDI.189.162 (“ODIN”)
  and from the European Commission’s and University of Groningen’s CO-FUND Rosalind
  Franklin program. R.P.N. acknowledges funding from JWST programs GO-1933 and GO-2279.
  Support for this work was provided by NASA through the NASA Hubble Fellowship grant
  HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated
  by the Association of Universities for Research in Astronomy, Incorporated, under
  NASA contract NAS5-26555. This paper makes use of the ALMA data: ADS/JAO. ALMA #2022.1.00073.S,
  2018.1.00035.L, and 2013.1.00999.S. ALMA is a partnership of ESO (representing its
  member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and
  ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of
  Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The research
  of C.C.W. is supported by NOIRLab, which is managed by the Association of Universities
  for Research in Astronomy (AURA) under a cooperative agreement with the National
  Science Foundation.'
article_number: '92'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Ivo
  full_name: Labbe, Ivo
  last_name: Labbe
- first_name: Jenny E.
  full_name: Greene, Jenny E.
  last_name: Greene
- first_name: Rachel
  full_name: Bezanson, Rachel
  last_name: Bezanson
- first_name: Seiji
  full_name: Fujimoto, Seiji
  last_name: Fujimoto
- first_name: Lukas J.
  full_name: Furtak, Lukas J.
  last_name: Furtak
- first_name: Andy D.
  full_name: Goulding, Andy D.
  last_name: Goulding
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Pascal A.
  full_name: Oesch, Pascal A.
  last_name: Oesch
- first_name: Hakim
  full_name: Atek, Hakim
  last_name: Atek
- first_name: Gabriel
  full_name: Brammer, Gabriel
  last_name: Brammer
- first_name: Iryna
  full_name: Chemerynska, Iryna
  last_name: Chemerynska
- first_name: Dan
  full_name: Coe, Dan
  last_name: Coe
- first_name: Sam E.
  full_name: Cutler, Sam E.
  last_name: Cutler
- first_name: Pratika
  full_name: Dayal, Pratika
  last_name: Dayal
- first_name: Robert
  full_name: Feldmann, Robert
  last_name: Feldmann
- first_name: Marijn
  full_name: Franx, Marijn
  last_name: Franx
- first_name: Karl
  full_name: Glazebrook, Karl
  last_name: Glazebrook
- first_name: Joel
  full_name: Leja, Joel
  last_name: Leja
- first_name: Michael
  full_name: Maseda, Michael
  last_name: Maseda
- first_name: Danilo
  full_name: Marchesini, Danilo
  last_name: Marchesini
- first_name: Themiya
  full_name: Nanayakkara, Themiya
  last_name: Nanayakkara
- first_name: Erica J.
  full_name: Nelson, Erica J.
  last_name: Nelson
- first_name: Richard
  full_name: Pan, Richard
  last_name: Pan
- first_name: Casey
  full_name: Papovich, Casey
  last_name: Papovich
- first_name: Sedona H.
  full_name: Price, Sedona H.
  last_name: Price
- first_name: Katherine A.
  full_name: Suess, Katherine A.
  last_name: Suess
- first_name: Bingjie 冰洁
  full_name: Wang, Bingjie 冰洁
  last_name: Wang
- first_name: John R.
  full_name: Weaver, John R.
  last_name: Weaver
- first_name: Katherine E.
  full_name: Whitaker, Katherine E.
  last_name: Whitaker
- first_name: Christina C.
  full_name: Williams, Christina C.
  last_name: Williams
- first_name: Adi
  full_name: Zitrin, Adi
  last_name: Zitrin
citation:
  ama: 'Labbe I, Greene JE, Bezanson R, et al. UNCOVER: Candidate red active galactic
    nuclei at 3 &#60; z &#60; 7 with JWST and ALMA. <i>The Astrophysical Journal</i>.
    2024;978. doi:<a href="https://doi.org/10.3847/1538-4357/ad3551">10.3847/1538-4357/ad3551</a>'
  apa: 'Labbe, I., Greene, J. E., Bezanson, R., Fujimoto, S., Furtak, L. J., Goulding,
    A. D., … Zitrin, A. (2024). UNCOVER: Candidate red active galactic nuclei at 3
    &#60; z &#60; 7 with JWST and ALMA. <i>The Astrophysical Journal</i>. IOP Publishing.
    <a href="https://doi.org/10.3847/1538-4357/ad3551">https://doi.org/10.3847/1538-4357/ad3551</a>'
  chicago: 'Labbe, Ivo, Jenny E. Greene, Rachel Bezanson, Seiji Fujimoto, Lukas J.
    Furtak, Andy D. Goulding, Jorryt J Matthee, et al. “UNCOVER: Candidate Red Active
    Galactic Nuclei at 3 &#60; z &#60; 7 with JWST and ALMA.” <i>The Astrophysical
    Journal</i>. IOP Publishing, 2024. <a href="https://doi.org/10.3847/1538-4357/ad3551">https://doi.org/10.3847/1538-4357/ad3551</a>.'
  ieee: 'I. Labbe <i>et al.</i>, “UNCOVER: Candidate red active galactic nuclei at
    3 &#60; z &#60; 7 with JWST and ALMA,” <i>The Astrophysical Journal</i>, vol.
    978. IOP Publishing, 2024.'
  ista: 'Labbe I, Greene JE, Bezanson R, Fujimoto S, Furtak LJ, Goulding AD, Matthee
    JJ, Naidu RP, Oesch PA, Atek H, Brammer G, Chemerynska I, Coe D, Cutler SE, Dayal
    P, Feldmann R, Franx M, Glazebrook K, Leja J, Maseda M, Marchesini D, Nanayakkara
    T, Nelson EJ, Pan R, Papovich C, Price SH, Suess KA, Wang B冰洁, Weaver JR, Whitaker
    KE, Williams CC, Zitrin A. 2024. UNCOVER: Candidate red active galactic nuclei
    at 3 &#60; z &#60; 7 with JWST and ALMA. The Astrophysical Journal. 978, 92.'
  mla: 'Labbe, Ivo, et al. “UNCOVER: Candidate Red Active Galactic Nuclei at 3 &#60;
    z &#60; 7 with JWST and ALMA.” <i>The Astrophysical Journal</i>, vol. 978, 92,
    IOP Publishing, 2024, doi:<a href="https://doi.org/10.3847/1538-4357/ad3551">10.3847/1538-4357/ad3551</a>.'
  short: I. Labbe, J.E. Greene, R. Bezanson, S. Fujimoto, L.J. Furtak, A.D. Goulding,
    J.J. Matthee, R.P. Naidu, P.A. Oesch, H. Atek, G. Brammer, I. Chemerynska, D.
    Coe, S.E. Cutler, P. Dayal, R. Feldmann, M. Franx, K. Glazebrook, J. Leja, M.
    Maseda, D. Marchesini, T. Nanayakkara, E.J. Nelson, R. Pan, C. Papovich, S.H.
    Price, K.A. Suess, B.冰洁 Wang, J.R. Weaver, K.E. Whitaker, C.C. Williams, A. Zitrin,
    The Astrophysical Journal 978 (2024).
date_created: 2026-01-28T15:26:12Z
date_published: 2024-12-26T00:00:00Z
date_updated: 2026-02-10T06:49:49Z
day: '26'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/ad3551
external_id:
  arxiv:
  - '2306.07320'
file:
- access_level: open_access
  checksum: 825c35ebd26e292c8a5c2bffac327854
  content_type: application/pdf
  creator: dernst
  date_created: 2026-02-10T06:44:24Z
  date_updated: 2026-02-10T06:44:24Z
  file_id: '21201'
  file_name: 2024_AstrophysicalJourn_Labbe.pdf
  file_size: 5041924
  relation: main_file
  success: 1
file_date_updated: 2026-02-10T06:44:24Z
fulldoi: https://doi.org/10.3847/1538-4357/ad3551
has_accepted_license: '1'
intvolume: '       978'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'UNCOVER: Candidate red active galactic nuclei at 3 < z < 7 with JWST and ALMA'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 978
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '21304'
abstract:
- lang: eng
  text: No description provided.
article_processing_charge: No
author:
- first_name: Miguel
  full_name: Santana de Freitas Amaral, Miguel
  id: 4f2d02dd-47a9-11ec-ad10-82820ed3f501
  last_name: Santana de Freitas Amaral
citation:
  ama: 'Santana de Freitas Amaral M. archaeal_membranes : code and examples. 2024.
    doi:<a href="https://doi.org/10.5281/ZENODO.13934991">10.5281/ZENODO.13934991</a>'
  apa: 'Santana de Freitas Amaral, M. (2024). archaeal_membranes : code and examples.
    Zenodo. <a href="https://doi.org/10.5281/ZENODO.13934991">https://doi.org/10.5281/ZENODO.13934991</a>'
  chicago: 'Santana de Freitas Amaral, Miguel. “Archaeal_membranes : Code and Examples.”
    Zenodo, 2024. <a href="https://doi.org/10.5281/ZENODO.13934991">https://doi.org/10.5281/ZENODO.13934991</a>.'
  ieee: 'M. Santana de Freitas Amaral, “archaeal_membranes : code and examples.” Zenodo,
    2024.'
  ista: 'Santana de Freitas Amaral M. 2024. archaeal_membranes : code and examples,
    Zenodo, <a href="https://doi.org/10.5281/ZENODO.13934991">10.5281/ZENODO.13934991</a>.'
  mla: 'Santana de Freitas Amaral, Miguel. <i>Archaeal_membranes : Code and Examples</i>.
    Zenodo, 2024, doi:<a href="https://doi.org/10.5281/ZENODO.13934991">10.5281/ZENODO.13934991</a>.'
  short: M. Santana de Freitas Amaral, (2024).
corr_author: '1'
date_created: 2026-02-17T12:52:26Z
date_published: 2024-10-15T00:00:00Z
date_updated: 2026-02-23T11:49:05Z
day: '15'
department:
- _id: AnSa
doi: 10.5281/ZENODO.13934991
fulldoi: https://doi.org/10.5281/ZENODO.13934991
has_accepted_license: '1'
main_file_link:
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  url: https://doi.org/10.5281/ZENODO.13934991
month: '10'
oa: 1
oa_version: Published Version
publisher: Zenodo
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status: public
title: 'archaeal_membranes : code and examples'
tmp:
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  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
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type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
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...
