---
APC_amount: 3711,01 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18488'
abstract:
- lang: eng
text: The advancement of quantum simulators motivates the development of a theoretical
framework to assist with efficient state preparation in quantum many-body systems.
Generally, preparing a target entangled state via unitary evolution with time-dependent
couplings is a challenging task and very little is known about the existence of
solutions and their properties. In this work we develop a constructive approach
for preparing matrix product states (MPS) via continuous unitary evolution. We
provide an explicit construction of the operator that exactly implements the evolution
of a given MPS along a specified direction in its tangent space. This operator
can be written as a sum of local terms of finite range, yet it is in general non-Hermitian.
Relying on the explicit construction of the non-Hermitian generator of the dynamics,
we demonstrate the existence of a Hermitian sequence of operators that implements
the desired MPS evolution with an error that decreases exponentially with the
operator range. The construction is benchmarked on an explicit periodic trajectory
in a translationally invariant MPS manifold. We demonstrate that the Floquet unitary
generating the dynamics over one period of the trajectory features an approximate
MPS-like eigenstate embedded among a sea of thermalizing eigenstates. These results
show that our construction is not only useful for state preparation and control
of many-body systems, but also provides a generic route towards Floquet scars—periodically
driven models with quasilocal generators of dynamics that have exact MPS eigenstates
in their spectrum.
acknowledgement: We thank L. Piroli, S. Garratt, and A. Molnár for insightful discussions.
This research was funded in part by the European Research Council (ERC) under the
European Union’s Horizon 2020 research and innovation programme (Grant Agreements
No. 850899 and No. 863476), the Austrian Science Fund (FWF) (Grant DOIs 10.55776/COE1,
10.55776/P36305, and 10.55776/F71), and the European Union (NextGenerationEU). This
work was performed in part at the Aspen Center for Physics, which is supported by
National Science Foundation Grant PHY-2210452. This research was supported in part
by NSF Grant PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP).
article_number: '040311'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Elena
full_name: Petrova, Elena
id: 0ac84990-897b-11ed-a09c-f5abb56a4ede
last_name: Petrova
- first_name: Norbert
full_name: Schuch, Norbert
last_name: Schuch
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Ljubotina M, Petrova E, Schuch N, Serbyn M. Tangent space generators of matrix
product states and exact floquet quantum scars. PRX Quantum. 2024;5(4).
doi:10.1103/prxquantum.5.040311
apa: Ljubotina, M., Petrova, E., Schuch, N., & Serbyn, M. (2024). Tangent space
generators of matrix product states and exact floquet quantum scars. PRX Quantum.
American Physical Society. https://doi.org/10.1103/prxquantum.5.040311
chicago: Ljubotina, Marko, Elena Petrova, Norbert Schuch, and Maksym Serbyn. “Tangent
Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX
Quantum. American Physical Society, 2024. https://doi.org/10.1103/prxquantum.5.040311.
ieee: M. Ljubotina, E. Petrova, N. Schuch, and M. Serbyn, “Tangent space generators
of matrix product states and exact floquet quantum scars,” PRX Quantum,
vol. 5, no. 4. American Physical Society, 2024.
ista: Ljubotina M, Petrova E, Schuch N, Serbyn M. 2024. Tangent space generators
of matrix product states and exact floquet quantum scars. PRX Quantum. 5(4), 040311.
mla: Ljubotina, Marko, et al. “Tangent Space Generators of Matrix Product States
and Exact Floquet Quantum Scars.” PRX Quantum, vol. 5, no. 4, 040311, American
Physical Society, 2024, doi:10.1103/prxquantum.5.040311.
short: M. Ljubotina, E. Petrova, N. Schuch, M. Serbyn, PRX Quantum 5 (2024).
corr_author: '1'
date_created: 2024-10-29T16:04:05Z
date_published: 2024-10-23T00:00:00Z
date_updated: 2025-09-08T14:26:29Z
day: '23'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/prxquantum.5.040311
ec_funded: 1
external_id:
arxiv:
- '2403.12325'
isi:
- '001346198800001'
file:
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checksum: 2e057ba021744d0a74602517935326b3
content_type: application/pdf
creator: dernst
date_created: 2024-10-30T08:59:09Z
date_updated: 2024-10-30T08:59:09Z
file_id: '18489'
file_name: 2024_PRXQuantum_Ljubotina.pdf
file_size: 1151431
relation: main_file
success: 1
file_date_updated: 2024-10-30T08:59:09Z
fulldoi: https://doi.org/10.1103/prxquantum.5.040311
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '4'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: PRX Quantum
publication_identifier:
eissn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tangent space generators of matrix product states and exact floquet quantum
scars
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18490'
abstract:
- lang: eng
text: 'For large classes of even-dimensional Riemannian manifolds (Formula presented.),
we construct and analyze conformally invariant random fields. These centered Gaussian
fields (Formula presented.), called co-polyharmonic Gaussian fields, are characterized
by their covariance kernels k which exhibit a precise logarithmic divergence:
(Formula presented.). They share a fundamental quasi-invariance property under
conformal transformations. In terms of the co-polyharmonic Gaussian field (Formula
presented.), we define the Liouville Quantum Gravity measure, a random measure
on (Formula presented.), heuristically given as (Formula presented.) and rigorously
obtained as almost sure weak limit of the right-hand side with (Formula presented.)
replaced by suitable regular approximations (Formula presented.). In terms on
the Liouville Quantum Gravity measure, we define the Liouville Brownian motion
on (Formula presented.) and the random GJMS operators. Finally, we present an
approach to a conformal field theory in arbitrary even dimension with an ansatz
based on Branson''s (Formula presented.) -curvature: we give a rigorous meaning
to the Polyakov–Liouville measure (Formula presented.) and we derive the corresponding
conformal anomaly. The set of admissible manifolds is conformally invariant. It
includes all compact 2-dimensional Riemannian manifolds, all compact non-negatively
curved Einstein manifolds of even dimension, and large classes of compact hyperbolic
manifolds of even dimension. However, not every compact even-dimensional Riemannian
manifold is admissible. Our results concerning the logarithmic divergence of the
kernel (Formula presented.) rely on new sharp estimates for heat kernels and higher
order Green kernels on arbitrary closed manifolds. '
acknowledgement: The authors are grateful to Masha Gordina for helpful references,
and to Nathanaël Berestycki, Baptiste Cerclé, and Ewain Gwynne for valuable comments
on the first circulated version of this paper. They also would like to thank Sebastian
Andres, Peter Friz, and Yizheng Yuan for pointing out an erroneous formulation in
the previous version of Theorem 5.7. Moreover, KTS would liketo express his thanks
to Sebastian Andres, Matthias Erbar, Martin Huesmann, and Jan Mass for stimulating
discussions on previous attempts to this project. LDS gratefully acknowledges financial
support from the European Research Council (grant agreement No 716117, awarded to
J. Maas), from the Austrian Science Fund (FWF) project 10.55776/ESP208, and from
the Austrian Science Fund (FWF) project 10.55776/F65.RH, EK, and KTS gratefully
acknowledge funding by the Deutsche Forschungsgemeinschaft through the project “Random
Riemannian Geometry” within the SPP 2265 “Random Geomet-ric Systems,” through the
Hausdorff Center for Mathematics (project ID 390685813), and through project B03
within the CRC 1060 (project ID 211504053). RH and KTS also gratefully acknowledge
financial support from the European Research Council through the ERC AdG “RicciBounds”(grant
agreement 694405).Data sharing not applicable to this article as no datasets were
generated or analyzed during the current study. Open access funding enabled and
organized by Projekt DEAL.
article_number: e70003
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lorenzo
full_name: Dello Schiavo, Lorenzo
id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
last_name: Dello Schiavo
orcid: 0000-0002-9881-6870
- first_name: Ronan
full_name: Herry, Ronan
last_name: Herry
- first_name: Eva
full_name: Kopfer, Eva
last_name: Kopfer
- first_name: Karl Theodor
full_name: Sturm, Karl Theodor
last_name: Sturm
citation:
ama: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. Conformally invariant random
fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian
manifolds of even dimension. Journal of the London Mathematical Society.
2024;110(5). doi:10.1112/jlms.70003
apa: Dello Schiavo, L., Herry, R., Kopfer, E., & Sturm, K. T. (2024). Conformally
invariant random fields, Liouville quantum gravity measures, and random Paneitz
operators on Riemannian manifolds of even dimension. Journal of the London
Mathematical Society. London Mathematical Society. https://doi.org/10.1112/jlms.70003
chicago: Dello Schiavo, Lorenzo, Ronan Herry, Eva Kopfer, and Karl Theodor Sturm.
“Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and
Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal
of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/jlms.70003.
ieee: L. Dello Schiavo, R. Herry, E. Kopfer, and K. T. Sturm, “Conformally invariant
random fields, Liouville quantum gravity measures, and random Paneitz operators
on Riemannian manifolds of even dimension,” Journal of the London Mathematical
Society, vol. 110, no. 5. London Mathematical Society, 2024.
ista: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. 2024. Conformally invariant
random fields, Liouville quantum gravity measures, and random Paneitz operators
on Riemannian manifolds of even dimension. Journal of the London Mathematical
Society. 110(5), e70003.
mla: Dello Schiavo, Lorenzo, et al. “Conformally Invariant Random Fields, Liouville
Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds
of Even Dimension.” Journal of the London Mathematical Society, vol. 110,
no. 5, e70003, London Mathematical Society, 2024, doi:10.1112/jlms.70003.
short: L. Dello Schiavo, R. Herry, E. Kopfer, K.T. Sturm, Journal of the London
Mathematical Society 110 (2024).
date_created: 2024-11-03T23:01:44Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2025-09-08T14:29:45Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1112/jlms.70003
ec_funded: 1
external_id:
isi:
- '001351918100029'
file:
- access_level: open_access
checksum: 143816823b5f43bd3748da8e3e91cef5
content_type: application/pdf
creator: dernst
date_created: 2024-11-04T08:54:26Z
date_updated: 2024-11-04T08:54:26Z
file_id: '18497'
file_name: 2024_JourLondonMathSoc_Schiavo.pdf
file_size: 911476
relation: main_file
success: 1
file_date_updated: 2024-11-04T08:54:26Z
fulldoi: https://doi.org/10.1112/jlms.70003
has_accepted_license: '1'
intvolume: ' 110'
isi: 1
issue: '5'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c
grant_number: E208
name: Configuration Spaces over Non-Smooth Spaces
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
publication: Journal of the London Mathematical Society
publication_identifier:
eissn:
- 1469-7750
issn:
- 0024-6107
publication_status: published
publisher: London Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Conformally invariant random fields, Liouville quantum gravity measures, and
random Paneitz operators on Riemannian manifolds of even dimension
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 110
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18494'
abstract:
- lang: eng
text: We expect luminous (M 1450 ≲ −26.5) high-redshift quasars to trace the highest-density
peaks in the early Universe. Here, we present observations of four z ≳ 6 quasar
fields using JWST/NIRCam in the imaging and wide-field slitless spectroscopy mode
and report a wide range in the number of detected [O iii]-emitting galaxies in
the quasars’ environments, ranging between a density enhancement of δ ≈ 65 within
a 2 cMpc radius—one of the largest protoclusters during the Epoch of Reionization
discovered to date—to a density contrast consistent with zero, indicating the
presence of a UV-luminous quasar in a region comparable to the average density
of the Universe. By measuring the two-point cross-correlation function of quasars
and their surrounding galaxies, as well as the galaxy autocorrelation function,
we infer a correlation length of quasars at 〈z〉 = 6.25 of r 0 QQ = 22.0 − 2.9
+ 3.0 cMpc h − 1 , while we obtain a correlation length of the [O iii]-emitting
galaxies of r 0 GG = 4.1 ± 0.3 cMpc h − 1 . By comparing the correlation functions
to dark-matter-only simulations we estimate the minimum mass of the quasars’ host
dark matter halos to be log 10 ( M halo , min / M ⊙ ) = 12.43 − 0.15 + 0.13 (and
log 10 ( M halo , min [ OIII ] / M ⊙ ) = 10.56 − 0.03 + 0.05 for the [O iii] emitters),
indicating that (a) luminous quasars do not necessarily reside within the most
overdense regions in the early Universe, and that (b) the UV-luminous duty cycle
of quasar activity at these redshifts is f duty ≪ 1. Such short quasar activity
timescales challenge our understanding of early supermassive black hole growth
and provide evidence for highly dust-obscured growth phases or episodic, radiatively
inefficient accretion rates.
acknowledgement: "The authors would like to thank the anonymous referee for the thoughtful
comments, which significantly improved our manuscript, and Jan-Torge Schindler,
Jiamu Huang, and Feige Wang for helpful discussions.\r\n\r\nJ.F.H. and E.P. acknowledge
support from the European Research Council (ERC) under the European Unions Horizon
2020 research and innovation program (grant agreement No. 885301). J.M. acknowledges
support from the European Union (ERC, AGENTS, 101076224).\r\n\r\nThis work is based
on observations made with the NASA/ESA/CSA James Webb Space Telescope. The JWST
data presented in this article were obtained from the Mikulski Archive for Space
Telescopes at the Space Telescope Science Institute, which is operated by the Association
of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127
for JWST. The specific observations analyzed are associated with program #1243 and
can be accessed via doi:10.17909/m5mp-5v90.\r\n\r\nThis work used the DiRAC Memory
Intensive service (Cosma8) at the University of Durham, which is part of the STFC
DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through
a Directors Discretionary Time allocation in 2023/24, under the auspices of the
UKRI-funded DiRAC Federation Project. The equipment was funded by BEIS capital funding
via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1,
Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National
e-Infrastructure.\r\n\r\nWe thank the Instituto de Astrofisica de Andalucia (IAA-CSIC),
Centro de Supercomputacion de Galicia (CESGA), and Spanish Academic and Research
Network (RedIRIS) in Spain for hosting Uchuu DR1, DR2, and DR3 in the Skies & Universes
site for cosmological simulations. The Uchuu simulations were carried out on the
Aterui II supercomputer at the Center for Computational Astrophysics, CfCA, of the
National Astronomical Observatory of Japan, and the K computer at the RIKEN Advanced
Institute for Computational Science. The Uchuu Data Releases efforts have made use
of the skunIAA_RedIRIS and skun6IAA computer facilities managed by the IAA-CSIC
in Spain (MICINN EU-Feder grant EQC2018-004366-P)."
article_number: '275'
article_processing_charge: Yes
article_type: original
author:
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Ruari
full_name: Mackenzie, Ruari
last_name: Mackenzie
- first_name: Elia
full_name: Pizzati, Elia
last_name: Pizzati
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Joseph F.
full_name: Hennawi, Joseph F.
last_name: Hennawi
- first_name: Haowen
full_name: Zhang, Haowen
last_name: Zhang
- first_name: Rongmon
full_name: Bordoloi, Rongmon
last_name: Bordoloi
- first_name: Daichi
full_name: Kashino, Daichi
last_name: Kashino
- first_name: Simon J.
full_name: Lilly, Simon J.
last_name: Lilly
- first_name: Rohan P.
full_name: Naidu, Rohan P.
last_name: Naidu
- first_name: Robert A.
full_name: Simcoe, Robert A.
last_name: Simcoe
- first_name: Minghao
full_name: Yue, Minghao
last_name: Yue
- first_name: Carlos S.
full_name: Frenk, Carlos S.
last_name: Frenk
- first_name: John C.
full_name: Helly, John C.
last_name: Helly
- first_name: Matthieu
full_name: Schaller, Matthieu
last_name: Schaller
- first_name: Joop
full_name: Schaye, Joop
last_name: Schaye
citation:
ama: Eilers AC, Mackenzie R, Pizzati E, et al. EIGER. VI. The correlation function,
host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical
Journal. 2024;974(2). doi:10.3847/1538-4357/ad778b
apa: Eilers, A. C., Mackenzie, R., Pizzati, E., Matthee, J. J., Hennawi, J. F.,
Zhang, H., … Schaye, J. (2024). EIGER. VI. The correlation function, host halo
mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal.
IOP Publishing. https://doi.org/10.3847/1538-4357/ad778b
chicago: Eilers, Anna Christina, Ruari Mackenzie, Elia Pizzati, Jorryt J Matthee,
Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, et al. “EIGER. VI. The Correlation
Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical
Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778b.
ieee: A. C. Eilers et al., “EIGER. VI. The correlation function, host halo
mass, and duty cycle of luminous quasars at z ≳ 6,” Astrophysical Journal,
vol. 974, no. 2. IOP Publishing, 2024.
ista: Eilers AC, Mackenzie R, Pizzati E, Matthee JJ, Hennawi JF, Zhang H, Bordoloi
R, Kashino D, Lilly SJ, Naidu RP, Simcoe RA, Yue M, Frenk CS, Helly JC, Schaller
M, Schaye J. 2024. EIGER. VI. The correlation function, host halo mass, and duty
cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 974(2), 275.
mla: Eilers, Anna Christina, et al. “EIGER. VI. The Correlation Function, Host Halo
Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal,
vol. 974, no. 2, 275, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778b.
short: A.C. Eilers, R. Mackenzie, E. Pizzati, J.J. Matthee, J.F. Hennawi, H. Zhang,
R. Bordoloi, D. Kashino, S.J. Lilly, R.P. Naidu, R.A. Simcoe, M. Yue, C.S. Frenk,
J.C. Helly, M. Schaller, J. Schaye, Astrophysical Journal 974 (2024).
date_created: 2024-11-03T23:01:45Z
date_published: 2024-10-01T00:00:00Z
date_updated: 2025-09-08T14:29:05Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/ad778b
external_id:
isi:
- '001338877100001'
file:
- access_level: open_access
checksum: 1fcac3d11d01d91cf2bb4963b6e10b22
content_type: application/pdf
creator: dernst
date_created: 2024-11-04T08:42:23Z
date_updated: 2024-11-04T08:42:23Z
file_id: '18496'
file_name: 2024_AstrophysicalJour_Eilers.pdf
file_size: 1042470
relation: main_file
success: 1
file_date_updated: 2024-11-04T08:42:23Z
fulldoi: https://doi.org/10.3847/1538-4357/ad778b
has_accepted_license: '1'
intvolume: ' 974'
isi: 1
issue: '2'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
grant_number: '101076224'
name: Young galaxies as tracers and agents of cosmic reionization
publication: Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous
quasars at z ≳ 6
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 974
year: '2024'
...
---
OA_place: repository
_id: '18498'
abstract:
- lang: eng
text: 'Scripts and data used in the research study Predicting rapid adaptation in
time from adaptation in space: a 30-year field experiment in marine snails. https://doi.org/10.1101/2023.09.27.559715'
article_processing_charge: No
author:
- first_name: Diego Fernando
full_name: Garcia Castillo, Diego Fernando
id: ae681a14-dc74-11ea-a0a7-c6ef18161701
last_name: Garcia Castillo
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Jenny
full_name: Larsson, Jenny
last_name: Larsson
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Data and code for: Predicting
rapid adaptation in time from adaptation in space: a 30-year field experiment
in marine snails. 2024. doi:10.5281/ZENODO.12159343'
apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski,
S., Butlin, R., … Westram, A. M. (2024). Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails.
Zenodo. https://doi.org/10.5281/ZENODO.12159343'
chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson,
Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Data
and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A
30-Year Field Experiment in Marine Snails.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.12159343.'
ieee: 'D. F. Garcia Castillo et al., “Data and code for: Predicting rapid
adaptation in time from adaptation in space: a 30-year field experiment in marine
snails.” Zenodo, 2024.'
ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R,
Johannesson K, Westram AM. 2024. Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails,
Zenodo, 10.5281/ZENODO.12159343.'
mla: 'Garcia Castillo, Diego Fernando, et al. Data and Code for: Predicting Rapid
Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine
Snails. Zenodo, 2024, doi:10.5281/ZENODO.12159343.'
short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R.
Butlin, K. Johannesson, A.M. Westram, (2024).
corr_author: '1'
date_created: 2024-11-04T09:33:17Z
date_published: 2024-06-19T00:00:00Z
date_updated: 2026-04-16T12:20:37Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5281/ZENODO.12159343
fulldoi: https://doi.org/10.5281/ZENODO.12159343
has_accepted_license: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.12159344
month: '06'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '20991'
relation: used_in_publication
status: public
- id: '18491'
relation: used_in_publication
status: public
status: public
title: 'Data and code for: Predicting rapid adaptation in time from adaptation in
space: a 30-year field experiment in marine snails'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: repository
OA_type: free access
_id: '18503'
abstract:
- lang: eng
text: "In 1996, Karger [Kar96] gave a startling randomized algorithm that finds
a minimum-cut in a (weighted) graph in time O(m log3 n) which he termed near-linear
time meaning linear (in the size of the input) times a polylogarthmic factor.
In this paper, we give the first deterministic algorithm which runs in near-linear
time for weighted graphs.\r\nPreviously, the breakthrough results of Kawarabayashi
and Thorup [KT19] gave a near-linear time algorithm for simple graphs (which was
improved to have running time O(m log2 n log log n) in [HRW20].) The main technique
here is a clustering procedure that perfectly preserves minimum cuts. Recently,
Li [Li21] gave an m1+o(1) deterministic minimum-cut algorithm for weighted graphs;
this form of running time has been termed “almost-linear”. Li uses almost-linear
time deterministic expander decompositions which do not perfectly preserve minimum
cuts, but he can use these clusterings to, in a sense, “derandomize” the methods
of Karger.\r\nIn terms of techniques, we provide a structural theorem that says
there exists a sparse clustering that preserves minimum cuts in a weighted graph
with o(1) error. In addition, we construct it deterministically in near linear
time. This was done exactly for simple graphs in [KT19, HRW20] and with polylogarithmic
error for weighted graphs in [Li21]. Extending the techniques in [KT19, HRW20]
to weighted graphs presents significant challenges, and moreover, the algorithm
can only polylogarithmically approximately preserve minimum cuts. A remaining
challenge is to reduce the polylogarithmic-approximate clusterings to 1 + o(1/
log n)-approximate so that they can be applied recursively as in [Li21] over O(log
n) many levels. This is an additional challenge that requires building on properties
of tree-packings in the presence of a wide range of edge weights to, for example,
find sources for local flow computations which identify minimum cuts that cross
clusters."
acknowledgement: This project has received funding from the European Research Council(ERC)
under the European Union’s Horizon 2020 research and innovation programme (Grant
agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDyn-Struct)”
and the Austrian Science Fund (FWF) project Z 422-N, project “Static and Dynamic
Hierarchical Graph Decompositions”, I 5982-N, and project “Fast Algorithms for a
Reactive Network Layer (ReactNet)”, P33775-N, with additional funding from the netidee
SCIENCE Stiftung, 2020–2024.
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Jason
full_name: Li, Jason
last_name: Li
- first_name: Satish
full_name: Rao, Satish
last_name: Rao
- first_name: Di
full_name: Wang, Di
last_name: Wang
citation:
ama: 'Henzinger M, Li J, Rao S, Wang D. Deterministic near-linear time minimum cut
in weighted graphs. In: 35th Annual ACM-SIAM Symposium on Discrete Algorithms.
Society for Industrial and Applied Mathematics; 2024:3089-3139. doi:10.1137/1.9781611977912.111'
apa: 'Henzinger, M., Li, J., Rao, S., & Wang, D. (2024). Deterministic near-linear
time minimum cut in weighted graphs. In 35th Annual ACM-SIAM Symposium on Discrete
Algorithms (pp. 3089–3139). Alexandria, VA, United States: Society for Industrial
and Applied Mathematics. https://doi.org/10.1137/1.9781611977912.111'
chicago: Henzinger, Monika, Jason Li, Satish Rao, and Di Wang. “Deterministic Near-Linear
Time Minimum Cut in Weighted Graphs.” In 35th Annual ACM-SIAM Symposium on
Discrete Algorithms, 3089–3139. Society for Industrial and Applied Mathematics,
2024. https://doi.org/10.1137/1.9781611977912.111.
ieee: M. Henzinger, J. Li, S. Rao, and D. Wang, “Deterministic near-linear time
minimum cut in weighted graphs,” in 35th Annual ACM-SIAM Symposium on Discrete
Algorithms, Alexandria, VA, United States, 2024, pp. 3089–3139.
ista: 'Henzinger M, Li J, Rao S, Wang D. 2024. Deterministic near-linear time minimum
cut in weighted graphs. 35th Annual ACM-SIAM Symposium on Discrete Algorithms.
SODA: Symposium on Discrete Algorithms, 3089–3139.'
mla: Henzinger, Monika, et al. “Deterministic Near-Linear Time Minimum Cut in Weighted
Graphs.” 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society
for Industrial and Applied Mathematics, 2024, pp. 3089–139, doi:10.1137/1.9781611977912.111.
short: M. Henzinger, J. Li, S. Rao, D. Wang, in:, 35th Annual ACM-SIAM Symposium
on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024,
pp. 3089–3139.
conference:
end_date: 2024-01-10
location: Alexandria, VA, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2024-01-07
corr_author: '1'
date_created: 2024-11-04T10:54:21Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-06-24T12:09:26Z
day: '04'
department:
- _id: MoHe
doi: 10.1137/1.9781611977912.111
ec_funded: 1
external_id:
arxiv:
- '2401.05627'
fulldoi: https://doi.org/10.1137/1.9781611977912.111
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2401.05627
month: '01'
oa: 1
oa_version: Preprint
page: 3089-3139
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
call_identifier: H2020
grant_number: '101019564'
name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
grant_number: Z00422
name: Efficient algorithms
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
grant_number: I05982
name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
grant_number: P33775
name: Fast Algorithms for a Reactive Network Layer
publication: 35th Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
eisbn:
- '9781611977912'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deterministic near-linear time minimum cut in weighted graphs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: publisher
OA_type: gold
_id: '18515'
abstract:
- lang: eng
text: "Understanding the role of evolutionary processes in shaping genetic variation
has been a\r\nprimary goal in evolutionary genetics. In this regard, a key question
is how genetically\r\ndistinct populations evolve in the face of gene flow, thereby
generating genetic and\r\nphenotypic divergence and reproductive isolation (RI).
This requires quantifying the role\r\nand relative contributions of prezygotic
and postzygotic isolating mechanisms on the\r\nreduction of gene exchange between
populations, and identifying regions in the genome\r\nthat mediate RI, which is
often polygenic. Further, this needs distinguishing neutral and\r\nselected regions
in the genome, and discerning how selection influences patterns of neutral\r\ndivergence.\r\nPopulation
structure, defined as any deviation from panmixia, such as geographic distribution,
movement and mating patterns of individuals, influences how genetic variation
is\r\nstructured in space and shapes the neutral null model. Availability of large
scale spatial\r\ngenomic datasets now enables us to detect signatures of population
structure in genetic\r\ndata and infer population genetic parameters. Such inferences
are crucial and have wide\r\napplications in biodiversity, conservation genetics,
population management and medical\r\ngenetics. However, inferences are based on
assumptions that do not always match the\r\ncomplex reality, thus leading to erroneous
conclusions. Moreover, the role and interaction\r\nof heterogeneous population
density and dispersal, which are ubiquitous in nature, has\r\nbeen challenging
to study owing to their mathematical complexity. In such scenarios,\r\nfeedback
between theory, data and simulations can prove to be useful.\r\nIn this thesis,
I examine the effect of population structure on neutral genetic variation\r\nand
barriers to gene exchange in hybridising populations, thereby bridging together
the\r\nfields of spatial population genetics and speciation.\r\nDespite being
a key concept in speciation, reproductive isolation (RI) lacks a quantitative\r\ndefinition
and has been used and measured differently across different fields. Chapter 2\r\ngives
a quantitative definition of RI, in terms of the effect of genetic differences
on gene\r\nflow. We give analytical predictions for RI in a range of scenarios,
in terms of effective migration rates for discrete populations and barrier strength
for continuous populations.\r\nIn addition to this, we discuss current measures
of RI and their limitations, and propose\r\nthe need for new measures that combine
organismal and genetic perspectives of RI.\r\nIn chapter 3, I examine the combined
effect of assortative mating, sexual selection\r\nand viability selection on RI.
For this, we consider a polygenic ‘magic’ trait under a\r\nmainland-island model.
We obtain novel theoretical predictions for molecular divergence\r\nin terms of
effective migration rates, which bears a simple relationship to measurable\r\nfitness
components of migrants and various early generation hybrids. We explore the\r\nconditions
under which local adaptation can be maintained despite maladaptive gene flow\r\nand
quantify the relative contributions of viability and sexual selection to genome-wide\r\nbarriers
to gene flow.\r\nThe next two chapters of the thesis focus on a hybrid zone of
Antirrhinum majus that\r\nconsist of two subspecies- the magenta flowered A. m.
pseudomajus and the yellow\r\nflowered A.m. striatum. Previous studies have suggested
that flower colour is target of\r\npollinator mediated selection and is influenced
only by few genes. While these regions\r\nshow high genetic differentiation between
the subspecies, the rest of the genome is seen\r\nto be well mixed. Chapter 4
examines the effects of heterogeneous population density\r\nand leptokurtic dispersal
on isolation by distance and the distribution of heterozygosity\r\nby focusing
on non-flower colour markers.\r\nChapter 5 analyses cline shapes and associations
among 6 focal flower colour markers to\r\nunderstand how selection and dispersal
maintain this hybrid zone. We see sharp coincident\r\nstepped clines at all loci
and positive associations throughout the hybrid zone, contrary to\r\nthe expected
patterns from diffusive gene flow. With a novel scheme of inferring dispersal\r\ncombined
with multilocus simulations, we show that stepped clines do not reflect genetic\r\nbarriers
to gene flow, but are rather a result of long-distance migration. This framework\r\nallows
us to get realistic estimates gene flow and selection and shows how traditional
cline\r\nanalysis may lead to inaccurate conclusions when assumptions of the theory
are not met.\r\nOverall, this thesis investigates how different features of population
structure leave\r\ndetectable signatures in genetic variation, namely in patterns
of isolation by distance,\r\nlinkage disequilibrium and genetic divergence. It
also highlights how effective migration\r\nrates provide useful way of analysing
polygenic architectures and shed new light into\r\nhybrid zones. In doing so,
I identify scenarios when simple models become insufficient\r\nand suggest possibe
directions by combining genetic data with simulations."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "I also acknowledge the funding agencies Marie Curie COFUND Doctoral
Fellowship,\r\nAustrian Science Fund FWF (grant P32166) and ERC (grant PR1000ERC02)
for financially\r\nsupporting my research over the years."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Parvathy
full_name: Surendranadh, Parvathy
id: 455235B8-F248-11E8-B48F-1D18A9856A87
last_name: Surendranadh
orcid: 0000-0001-6395-386X
citation:
ama: Surendranadh P. Effect of population structure on neutral genetic variation
and barriers to gene exchange. 2024. doi:10.15479/at:ista:18515
apa: Surendranadh, P. (2024). Effect of population structure on neutral genetic
variation and barriers to gene exchange. Institute of Science and Technology
Austria. https://doi.org/10.15479/at:ista:18515
chicago: Surendranadh, Parvathy. “Effect of Population Structure on Neutral Genetic
Variation and Barriers to Gene Exchange.” Institute of Science and Technology
Austria, 2024. https://doi.org/10.15479/at:ista:18515.
ieee: P. Surendranadh, “Effect of population structure on neutral genetic variation
and barriers to gene exchange,” Institute of Science and Technology Austria, 2024.
ista: Surendranadh P. 2024. Effect of population structure on neutral genetic variation
and barriers to gene exchange. Institute of Science and Technology Austria.
mla: Surendranadh, Parvathy. Effect of Population Structure on Neutral Genetic
Variation and Barriers to Gene Exchange. Institute of Science and Technology
Austria, 2024, doi:10.15479/at:ista:18515.
short: P. Surendranadh, Effect of Population Structure on Neutral Genetic Variation
and Barriers to Gene Exchange, Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-11-06T21:25:37Z
date_published: 2024-11-07T00:00:00Z
date_updated: 2026-04-07T12:56:52Z
day: '07'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: NiBa
doi: 10.15479/at:ista:18515
file:
- access_level: open_access
checksum: c32cf7bc75748d9c551d8eb70178bbec
content_type: application/pdf
creator: psurendr
date_created: 2024-11-07T10:59:29Z
date_updated: 2024-11-07T10:59:29Z
file_id: '18519'
file_name: PhD_Thesis__Parvathy_071124_PDFA.pdf
file_size: 37019760
relation: main_file
success: 1
- access_level: closed
checksum: 4417e02d54084d89e75734e18caaa96d
content_type: application/zip
creator: psurendr
date_created: 2024-11-07T10:59:42Z
date_updated: 2024-11-07T10:59:42Z
file_id: '18520'
file_name: PhD Thesis- Parvathy_071124.zip
file_size: 41198857
relation: source_file
file_date_updated: 2024-11-07T10:59:42Z
fulldoi: https://doi.org/10.15479/at:ista:18515
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: '219'
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
grant_number: P32166
name: Snapdragon Speciation
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
grant_number: '101055327'
name: Understanding the evolution of continuous genomes
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
title: Effect of population structure on neutral genetic variation and barriers to
gene exchange
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
APC_amount: 2748 EUR
OA_place: publisher
OA_type: hybrid
_id: '18521'
abstract:
- lang: eng
text: In distributed systems with processes that do not share a global clock, partial
synchrony is achieved by clock synchronization that guarantees bounded clock skew
among all applications. Existing solutions for distributed runtime verification
under partial synchrony against temporal logic specifications are exact but suffer
from significant computational overhead. In this paper, we propose an approximate
distributed monitoring algorithm for Signal Temporal Logic (STL) that mitigates
this issue by abstracting away potential interleaving behaviors. This conservative
abstraction enables a significant speedup of the distributed monitors, albeit
with a tradeoff in accuracy. We address this tradeoff with a methodology that
combines our approximate monitor with its exact counterpart, resulting in enhanced
efficiency without sacrificing precision. We evaluate our approach with multiple
experiments, showcasing its efficacy in both real-world applications and synthetic
examples.
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. This
work is sponsored in part by the United States NSF CCF-2118356 award. This research
was partially funded by A-IQ Ready (Chips JU, grant agreement No. 101096658).
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
arxiv: 1
author:
- first_name: Borzoo
full_name: Bonakdarpour, Borzoo
last_name: Bonakdarpour
- first_name: Anik
full_name: Momtaz, Anik
last_name: Momtaz
- first_name: Dejan
full_name: Nickovic, Dejan
id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
last_name: Nickovic
- first_name: Naci E
full_name: Sarac, Naci E
id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425
last_name: Sarac
citation:
ama: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. Approximate distributed monitoring
under partial synchrony: Balancing speed & accuracy. In: 24th International
Conference on Runtime Verification. Vol 15191. Springer Nature; 2024:282-301.
doi:10.1007/978-3-031-74234-7_18'
apa: 'Bonakdarpour, B., Momtaz, A., Nickovic, D., & Sarac, N. E. (2024). Approximate
distributed monitoring under partial synchrony: Balancing speed & accuracy.
In 24th International Conference on Runtime Verification (Vol. 15191, pp.
282–301). Istanbul, Turkey: Springer Nature. https://doi.org/10.1007/978-3-031-74234-7_18'
chicago: 'Bonakdarpour, Borzoo, Anik Momtaz, Dejan Nickovic, and Naci E Sarac. “Approximate
Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.”
In 24th International Conference on Runtime Verification, 15191:282–301.
Springer Nature, 2024. https://doi.org/10.1007/978-3-031-74234-7_18.'
ieee: 'B. Bonakdarpour, A. Momtaz, D. Nickovic, and N. E. Sarac, “Approximate distributed
monitoring under partial synchrony: Balancing speed & accuracy,” in 24th
International Conference on Runtime Verification, Istanbul, Turkey, 2024,
vol. 15191, pp. 282–301.'
ista: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. 2024. Approximate distributed
monitoring under partial synchrony: Balancing speed & accuracy. 24th International
Conference on Runtime Verification. RV: Conference on Runtime Verification, LNCS,
vol. 15191, 282–301.'
mla: 'Bonakdarpour, Borzoo, et al. “Approximate Distributed Monitoring under Partial
Synchrony: Balancing Speed & Accuracy.” 24th International Conference on
Runtime Verification, vol. 15191, Springer Nature, 2024, pp. 282–301, doi:10.1007/978-3-031-74234-7_18.'
short: B. Bonakdarpour, A. Momtaz, D. Nickovic, N.E. Sarac, in:, 24th International
Conference on Runtime Verification, Springer Nature, 2024, pp. 282–301.
conference:
end_date: 2024-10-17
location: Istanbul, Turkey
name: 'RV: Conference on Runtime Verification'
start_date: 2024-10-15
corr_author: '1'
date_created: 2024-11-10T23:01:58Z
date_published: 2024-10-12T00:00:00Z
date_updated: 2026-05-20T08:43:20Z
day: '12'
ddc:
- '000'
department:
- _id: ToHe
- _id: GradSch
doi: 10.1007/978-3-031-74234-7_18
ec_funded: 1
external_id:
arxiv:
- '2408.05033'
isi:
- '001420093700018'
file:
- access_level: open_access
checksum: 7b8ca21b8c19ab796fa445b0e54003ca
content_type: application/pdf
creator: dernst
date_created: 2024-11-11T09:42:28Z
date_updated: 2024-11-11T09:42:28Z
file_id: '18539'
file_name: 2024_LNCS_Bonakdarpour.pdf
file_size: 1897101
relation: main_file
success: 1
file_date_updated: 2024-11-11T09:42:28Z
fulldoi: https://doi.org/10.1007/978-3-031-74234-7_18
has_accepted_license: '1'
intvolume: ' 15191'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 282-301
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
call_identifier: H2020
grant_number: '101020093'
name: Vigilant Algorithmic Monitoring of Software
publication: 24th International Conference on Runtime Verification
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783031742330'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Approximate distributed monitoring under partial synchrony: Balancing speed
& accuracy'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15191
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18522'
abstract:
- lang: eng
text: The Golgi apparatus is essential for protein sorting, yet its quality control
mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex
uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic length
of α-helical transmembrane domains (TMDs) at the Golgi. Thereby the Dsc complex
likely interacts with orphaned ER and Golgi proteins that have shorter TMDs and
ubiquitinates them for targeted degradation. Some Dsc substrates will be extracted
by Cdc48 for endosome and Golgi associated proteasomal degradation (EGAD), while
others will undergo ESCRT dependent vacuolar degradation. Some substrates are
degraded by both, EGAD- or ESCRT pathways. The accumulation of Dsc substrates
entails a specific increase in glycerophospholipids with shorter and asymmetric
fatty acyl chains. Hence, the Dsc complex mediates the selective degradation of
orphaned proteins at the sorting center of cells, which prevents their spreading
across other organelles and thereby preserves cellular membrane protein and lipid
composition.
acknowledgement: 'We thank Snezhana Oliferenko, Hesso Farhan, Chris Dunworth, and
Lukas A Huber for critically reading the manuscript, Ming Li, Peter Espenshade,
Sebastien Leon, and Scott Emr for reagents, Bob Kaufmann for help in characterizing
the Dsc2 L1 loop mutant. This research was funded in part by the Austrian Science
Fund (FWF) (10.55776/P32161, 10.55776/P34907, 10.55776/DOC82 to DT, and 10.55776/P36187
to OS), by a Lipotype lipidomics excellence award (LEA 2019) to OS, by a Luxembourg
National Research Fund (FNR): Grant #13571826 to YW, and by European Union’s Horizon
2020 research and innovation program under the Marie Skłodowska-Curie grant agreement
No. 847681 (to KRL). For open access purposes, the author has applied a CC BY public
copyright license to any author accepted manuscript version arising from this submission.'
article_number: '9257'
article_processing_charge: Yes
article_type: original
author:
- first_name: Yannick
full_name: Weyer, Yannick
last_name: Weyer
- first_name: Sinead I.
full_name: Schwabl, Sinead I.
last_name: Schwabl
- first_name: Xuechen
full_name: Tang, Xuechen
last_name: Tang
- first_name: Astha
full_name: Purwar, Astha
last_name: Purwar
- first_name: Konstantin
full_name: Siegmann, Konstantin
last_name: Siegmann
- first_name: Angela
full_name: Ruepp, Angela
last_name: Ruepp
- first_name: Theresia
full_name: Dunzendorfer-Matt, Theresia
last_name: Dunzendorfer-Matt
- first_name: Michael A.
full_name: Widerin, Michael A.
last_name: Widerin
- first_name: Veronika
full_name: Niedrist, Veronika
last_name: Niedrist
- first_name: Noa J.M.
full_name: Mutsters, Noa J.M.
last_name: Mutsters
- first_name: Maria G.
full_name: Tettamanti, Maria G.
last_name: Tettamanti
- first_name: Sabine
full_name: Weys, Sabine
id: caffa136-9669-11ed-9092-ceac12ac9c05
last_name: Weys
- first_name: Bettina
full_name: Sarg, Bettina
last_name: Sarg
- first_name: Leopold
full_name: Kremser, Leopold
last_name: Kremser
- first_name: Klaus R.
full_name: Liedl, Klaus R.
last_name: Liedl
- first_name: Oliver
full_name: Schmidt, Oliver
last_name: Schmidt
- first_name: David
full_name: Teis, David
last_name: Teis
citation:
ama: Weyer Y, Schwabl SI, Tang X, et al. The Dsc ubiquitin ligase complex identifies
transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications.
2024;15. doi:10.1038/s41467-024-53676-6
apa: Weyer, Y., Schwabl, S. I., Tang, X., Purwar, A., Siegmann, K., Ruepp, A., …
Teis, D. (2024). The Dsc ubiquitin ligase complex identifies transmembrane degrons
to degrade orphaned proteins at the Golgi. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-024-53676-6
chicago: Weyer, Yannick, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin
Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, et al. “The Dsc Ubiquitin
Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at
the Golgi.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53676-6.
ieee: Y. Weyer et al., “The Dsc ubiquitin ligase complex identifies transmembrane
degrons to degrade orphaned proteins at the Golgi,” Nature Communications,
vol. 15. Springer Nature, 2024.
ista: Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt
T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser
L, Liedl KR, Schmidt O, Teis D. 2024. The Dsc ubiquitin ligase complex identifies
transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications.
15, 9257.
mla: Weyer, Yannick, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane
Degrons to Degrade Orphaned Proteins at the Golgi.” Nature Communications,
vol. 15, 9257, Springer Nature, 2024, doi:10.1038/s41467-024-53676-6.
short: Y. Weyer, S.I. Schwabl, X. Tang, A. Purwar, K. Siegmann, A. Ruepp, T. Dunzendorfer-Matt,
M.A. Widerin, V. Niedrist, N.J.M. Mutsters, M.G. Tettamanti, S. Weys, B. Sarg,
L. Kremser, K.R. Liedl, O. Schmidt, D. Teis, Nature Communications 15 (2024).
date_created: 2024-11-10T23:01:58Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2026-03-05T11:20:12Z
day: '01'
ddc:
- '570'
doi: 10.1038/s41467-024-53676-6
external_id:
isi:
- '001345548100007'
pmid:
- '39461958'
file:
- access_level: open_access
checksum: 32c986fc3babec999c03a5c043310f40
content_type: application/pdf
creator: dernst
date_created: 2025-01-22T14:36:33Z
date_updated: 2025-01-22T14:36:33Z
file_id: '18870'
file_name: 2024_NatureComm_Weyer.pdf
file_size: 5634494
relation: main_file
success: 1
file_date_updated: 2025-01-22T14:36:33Z
fulldoi: https://doi.org/10.1038/s41467-024-53676-6
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade
orphaned proteins at the Golgi
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18523'
abstract:
- lang: eng
text: "Recent observations from the EIGER JWST program have measured for the first
time the quasar–galaxy cross-correlation function at z ≈ 6. The autocorrelation
function of faint z ≈ 6 quasars was also recently estimated. These measurements
provide key insights into the properties of quasars and galaxies at high redshift
and their relation with the host dark matter haloes. In this work, we interpret
these data building upon an empirical quasar population model that has been applied
successfully to quasar clustering and demographic measurements at z ≈ 2–4. We
use a new, large-volume N-body simulation with more than a trillion particles,
FLAMINGO-10k, to model quasars and galaxies simultaneously. We successfully reproduce
observations of z ≈ 6 quasars and galaxies (i.e. their clustering properties and
luminosity functions), and infer key quantities such as their luminosity–halo
mass relation, the mass function of their host haloes, and their duty cycle/occupation
fraction. Our key findings\r\nare (i) quasars reside on average in ≈ 1012.5 M
haloes (corresponding to ≈ 5σ fluctuations in the initial conditions of the linear
density field), but the distribution of host halo masses is quite broad; (ii)
the duty cycle of (UV-bright) quasar activity is relatively low (≈ 1 per cent);
(iii) galaxies (that are bright in [O III]) live in much smaller haloes (≈ 1010.9
M) and have a larger duty cycle (occupation fraction) of ≈ 13 per cent. Finally,
we focus on the inferred properties of quasars and present a homogeneous analysis
of their evolution with redshift. The picture that emerges reveals a strong evolution
of the host halo mass and duty cycle of quasars at z ≈ 2–6, and calls for new
investigations of the role of quasar activity across cosmic time."
acknowledgement: "We are grateful to Junya Arita and the SHELLQs team for sharing
their data on the quasar autocorrelation function and to Jan-Torge Schindler for
discussion on the QLF. We acknowledge helpful conversations with the ENIGMA group
at UC Santa Barbara and Leiden University. EP is grateful to Rob McGibbon and Victor
Forouhar Moreno for help with the simulation outputs, and to Timo Kist, Jiamu Huang,
and Vikram Khaire for comments on an early version of the manuscript. JFH and EP
acknowledge support from the European Research Council (ERC) under the European
Union’s Horizon 2020 research and innovation program (grant agreement No 885301).
This work is partly supported by funding from the European Union’s Horizon 2020
research and innovation programme under the Marie Skłodowska-Curie grant agreement
No 860744 (BiD4BESt). FW acknowledges support from NSF grant AST-2308258. This work
used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which
is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources
was granted through a Director’s Discretionary Time allocation in 2023/24, under
the auspices of the UKRI-funded\r\nDiRAC Federation Project. The equipment was funded
by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1,
and ST/S002502/1, Durham University, and STFC operations grant ST/R000832/1. DiRAC
is part of the National e-Infrastructure."
article_processing_charge: Yes
article_type: original
author:
- first_name: Elia
full_name: Pizzati, Elia
last_name: Pizzati
- first_name: Joseph F.
full_name: Hennawi, Joseph F.
last_name: Hennawi
- first_name: Joop
full_name: Schaye, Joop
last_name: Schaye
- first_name: Matthieu
full_name: Schaller, Matthieu
last_name: Schaller
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Feige
full_name: Wang, Feige
last_name: Wang
- first_name: Carlos S.
full_name: Frenk, Carlos S.
last_name: Frenk
- first_name: Willem
full_name: Elbers, Willem
last_name: Elbers
- first_name: John C.
full_name: Helly, John C.
last_name: Helly
- first_name: Ruari
full_name: Mackenzie, Ruari
last_name: Mackenzie
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Rongmon
full_name: Bordoloi, Rongmon
last_name: Bordoloi
- first_name: Daichi
full_name: Kashino, Daichi
last_name: Kashino
- first_name: Rohan P.
full_name: Naidu, Rohan P.
last_name: Naidu
- first_name: Minghao
full_name: Yue, Minghao
last_name: Yue
citation:
ama: Pizzati E, Hennawi JF, Schaye J, et al. A unified model for the clustering
of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical
Society. 2024;534(4):3155-3175. doi:10.1093/mnras/stae2307
apa: Pizzati, E., Hennawi, J. F., Schaye, J., Schaller, M., Eilers, A. C., Wang,
F., … Yue, M. (2024). A unified model for the clustering of quasars and galaxies
at z ≈ 6. Monthly Notices of the Royal Astronomical Society. Oxford University
Press. https://doi.org/10.1093/mnras/stae2307
chicago: Pizzati, Elia, Joseph F. Hennawi, Joop Schaye, Matthieu Schaller, Anna
Christina Eilers, Feige Wang, Carlos S. Frenk, et al. “A Unified Model for the
Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal
Astronomical Society. Oxford University Press, 2024. https://doi.org/10.1093/mnras/stae2307.
ieee: E. Pizzati et al., “A unified model for the clustering of quasars and
galaxies at z ≈ 6,” Monthly Notices of the Royal Astronomical Society,
vol. 534, no. 4. Oxford University Press, pp. 3155–3175, 2024.
ista: Pizzati E, Hennawi JF, Schaye J, Schaller M, Eilers AC, Wang F, Frenk CS,
Elbers W, Helly JC, Mackenzie R, Matthee JJ, Bordoloi R, Kashino D, Naidu RP,
Yue M. 2024. A unified model for the clustering of quasars and galaxies at z ≈
6. Monthly Notices of the Royal Astronomical Society. 534(4), 3155–3175.
mla: Pizzati, Elia, et al. “A Unified Model for the Clustering of Quasars and Galaxies
at z ≈ 6.” Monthly Notices of the Royal Astronomical Society, vol. 534,
no. 4, Oxford University Press, 2024, pp. 3155–75, doi:10.1093/mnras/stae2307.
short: E. Pizzati, J.F. Hennawi, J. Schaye, M. Schaller, A.C. Eilers, F. Wang, C.S.
Frenk, W. Elbers, J.C. Helly, R. Mackenzie, J.J. Matthee, R. Bordoloi, D. Kashino,
R.P. Naidu, M. Yue, Monthly Notices of the Royal Astronomical Society 534 (2024)
3155–3175.
date_created: 2024-11-10T23:01:58Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2025-09-08T14:40:22Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1093/mnras/stae2307
external_id:
isi:
- '001335663900008'
file:
- access_level: open_access
checksum: 9ea6285dd1d04d7a9e7b40a4c9e11edb
content_type: application/pdf
creator: dernst
date_created: 2024-11-12T07:17:26Z
date_updated: 2024-11-12T07:17:26Z
file_id: '18542'
file_name: 2024_MonthlyNRoyalAstronSoc_Pizzati.pdf
file_size: 2954312
relation: main_file
success: 1
file_date_updated: 2024-11-12T07:17:26Z
fulldoi: https://doi.org/10.1093/mnras/stae2307
has_accepted_license: '1'
intvolume: ' 534'
isi: 1
issue: '4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 3155-3175
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A unified model for the clustering of quasars and galaxies at z ≈ 6
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 534
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18545'
abstract:
- lang: eng
text: Clinical implementation of therapeutic genome editing relies on efficient
in vivo delivery and the safety of CRISPR-Cas tools. Previously, we identified
PsCas9 as a Type II-B family enzyme capable of editing mouse liver genome upon
adenoviral delivery without detectable off-targets and reduced chromosomal translocations.
Yet, its efficacy remains insufficient with non-viral delivery, a common challenge
for many Cas9 orthologues. Here, we sought to redesign PsCas9 for in vivo editing
using lipid nanoparticles. We solve the PsCas9 ribonucleoprotein structure with
cryo-EM and characterize it biochemically, providing a basis for its rational
engineering. Screening over numerous guide RNA and protein variants lead us to
develop engineered PsCas9 (ePsCas9) with up to 20-fold increased activity across
various targets and preserved safety advantages. We apply the same design principles
to boost the activity of FnCas9, an enzyme phylogenetically relevant to PsCas9.
Remarkably, a single administration of mRNA encoding ePsCas9 and its guide formulated
with lipid nanoparticles results in high levels of editing in the Pcsk9 gene in
mouse liver, a clinically relevant target for hypercholesterolemia treatment.
Collectively, our findings introduce ePsCas9 as a highly efficient, and precise
tool for therapeutic genome editing, in addition to the engineering strategy applicable
to other Cas9 orthologues.
article_number: '9173'
article_processing_charge: Yes
article_type: original
author:
- first_name: Dmitrii
full_name: Degtev, Dmitrii
last_name: Degtev
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Aikaterini
full_name: Emmanouilidi, Aikaterini
last_name: Emmanouilidi
- first_name: Aleksandar
full_name: Zdravković, Aleksandar
last_name: Zdravković
- first_name: Oi Kuan
full_name: Choong, Oi Kuan
last_name: Choong
- first_name: Julia
full_name: Liz Touza, Julia
last_name: Liz Touza
- first_name: Niklas
full_name: Selfjord, Niklas
last_name: Selfjord
- first_name: Isabel
full_name: Weisheit, Isabel
last_name: Weisheit
- first_name: Margherita
full_name: Francescatto, Margherita
last_name: Francescatto
- first_name: Pinar
full_name: Akcakaya, Pinar
last_name: Akcakaya
- first_name: Michelle
full_name: Porritt, Michelle
last_name: Porritt
- first_name: Marcello
full_name: Maresca, Marcello
last_name: Maresca
- first_name: David
full_name: Taylor, David
last_name: Taylor
- first_name: Grzegorz
full_name: Sienski, Grzegorz
last_name: Sienski
citation:
ama: Degtev D, Bravo JPK, Emmanouilidi A, et al. Engineered PsCas9 enables therapeutic
genome editing in mouse liver with lipid nanoparticles. Nature Communications.
2024;15. doi:10.1038/s41467-024-53418-8
apa: Degtev, D., Bravo, J. P. K., Emmanouilidi, A., Zdravković, A., Choong, O. K.,
Liz Touza, J., … Sienski, G. (2024). Engineered PsCas9 enables therapeutic genome
editing in mouse liver with lipid nanoparticles. Nature Communications.
Springer Nature. https://doi.org/10.1038/s41467-024-53418-8
chicago: Degtev, Dmitrii, Jack Peter Kelly Bravo, Aikaterini Emmanouilidi, Aleksandar
Zdravković, Oi Kuan Choong, Julia Liz Touza, Niklas Selfjord, et al. “Engineered
PsCas9 Enables Therapeutic Genome Editing in Mouse Liver with Lipid Nanoparticles.”
Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53418-8.
ieee: D. Degtev et al., “Engineered PsCas9 enables therapeutic genome editing
in mouse liver with lipid nanoparticles,” Nature Communications, vol. 15.
Springer Nature, 2024.
ista: Degtev D, Bravo JPK, Emmanouilidi A, Zdravković A, Choong OK, Liz Touza J,
Selfjord N, Weisheit I, Francescatto M, Akcakaya P, Porritt M, Maresca M, Taylor
D, Sienski G. 2024. Engineered PsCas9 enables therapeutic genome editing in mouse
liver with lipid nanoparticles. Nature Communications. 15, 9173.
mla: Degtev, Dmitrii, et al. “Engineered PsCas9 Enables Therapeutic Genome Editing
in Mouse Liver with Lipid Nanoparticles.” Nature Communications, vol. 15,
9173, Springer Nature, 2024, doi:10.1038/s41467-024-53418-8.
short: D. Degtev, J.P.K. Bravo, A. Emmanouilidi, A. Zdravković, O.K. Choong, J.
Liz Touza, N. Selfjord, I. Weisheit, M. Francescatto, P. Akcakaya, M. Porritt,
M. Maresca, D. Taylor, G. Sienski, Nature Communications 15 (2024).
date_created: 2024-11-12T10:18:04Z
date_published: 2024-11-07T00:00:00Z
date_updated: 2024-11-13T08:19:50Z
day: '07'
ddc:
- '572'
doi: 10.1038/s41467-024-53418-8
extern: '1'
file:
- access_level: open_access
checksum: dcfadc806f4144d065eb8e2032554782
content_type: application/pdf
creator: jbravo
date_created: 2024-11-12T10:18:32Z
date_updated: 2024-11-12T10:18:32Z
file_id: '18546'
file_name: s41467-024-53418-8.pdf
file_size: 2967001
relation: main_file
success: 1
file_date_updated: 2024-11-12T10:18:32Z
fulldoi: https://doi.org/10.1038/s41467-024-53418-8
has_accepted_license: '1'
intvolume: ' 15'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '11'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid
nanoparticles
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18553'
abstract:
- lang: eng
text: Transcription-coupled nucleotide excision repair (TC-NER) efficiently eliminates
DNA damage that impedes gene transcription by RNA polymerase II (RNA Pol II).
TC-NER is initiated by the recognition of lesion-stalled RNA Pol II by CSB, which
recruits the CRL4CSA ubiquitin ligase and UVSSA. RNA Pol II ubiquitylation at
RPB1-K1268 by CRL4CSA serves as a critical TC-NER checkpoint, governing RNA Pol
II stability and initiating DNA damage excision by TFIIH recruitment. However,
the precise regulatory mechanisms of CRL4CSA activity and TFIIH recruitment remain
elusive. Here, we reveal human serine/threonine-protein kinase 19 (STK19) as a
TC-NER factor, which is essential for correct DNA damage removal and subsequent
transcription restart. Cryogenic electron microscopy (cryo-EM) studies demonstrate
that STK19 is an integral part of the RNA Pol II-TC-NER complex, bridging CSA,
UVSSA, RNA Pol II, and downstream DNA. STK19 stimulates TC-NER complex stability
and CRL4CSA activity, resulting in efficient RNA Pol II ubiquitylation and correct
UVSSA and TFIIH binding. These findings underscore the crucial role of STK19 as
a core TC-NER component.
acknowledged_ssus:
- _id: LifeSc
- _id: PreCl
acknowledgement: We thank N. Thompson and R. Burgess for the 8WG16 hybridoma cell
line. This research was further supported by the Scientific Service Units (SSU)
of IST Austria through resources provided by the Lab Support Facility (LSF) and
the Preclinical Facility (PCF). This work is part of the Oncode Institute, which
is partly financed by the Dutch Cancer Society. Research at the Netherlands Cancer
Institute is supported by institutional grants of the Dutch Cancer Society and the
Dutch Ministry of Health, Welfare and Sport. This study was supported by a VICI
(VI.C.182.025) and a TOP Grant (714.017.003) of the Netherlands Organization for
Scientific Research.
article_processing_charge: No
article_type: original
author:
- first_name: Anisha R.
full_name: Ramadhin, Anisha R.
last_name: Ramadhin
- first_name: Shun-Hsiao
full_name: Lee, Shun-Hsiao
last_name: Lee
- first_name: Di
full_name: Zhou, Di
last_name: Zhou
- first_name: Anita P
full_name: Testa Salmazo, Anita P
id: 41F1F098-F248-11E8-B48F-1D18A9856A87
last_name: Testa Salmazo
- first_name: Camila
full_name: Gonzalo-Hansen, Camila
last_name: Gonzalo-Hansen
- first_name: Marjolein
full_name: van Sluis, Marjolein
last_name: van Sluis
- first_name: Cindy M.A.
full_name: Blom, Cindy M.A.
last_name: Blom
- first_name: Roel C.
full_name: Janssens, Roel C.
last_name: Janssens
- first_name: Anja
full_name: Raams, Anja
last_name: Raams
- first_name: Dick
full_name: Dekkers, Dick
last_name: Dekkers
- first_name: Karel
full_name: Bezstarosti, Karel
last_name: Bezstarosti
- first_name: Dea
full_name: Slade, Dea
last_name: Slade
- first_name: Wim
full_name: Vermeulen, Wim
last_name: Vermeulen
- first_name: Alex
full_name: Pines, Alex
last_name: Pines
- first_name: Jeroen A.A.
full_name: Demmers, Jeroen A.A.
last_name: Demmers
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Titia K.
full_name: Sixma, Titia K.
last_name: Sixma
- first_name: Jurgen A.
full_name: Marteijn, Jurgen A.
last_name: Marteijn
citation:
ama: Ramadhin AR, Lee S-H, Zhou D, et al. STK19 drives transcription-coupled repair
by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH
recruitment. Molecular Cell. 2024;84(24):4740-4757.e12. doi:10.1016/j.molcel.2024.10.030
apa: Ramadhin, A. R., Lee, S.-H., Zhou, D., Testa Salmazo, A. P., Gonzalo-Hansen,
C., van Sluis, M., … Marteijn, J. A. (2024). STK19 drives transcription-coupled
repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and
TFIIH recruitment. Molecular Cell. Elsevier. https://doi.org/10.1016/j.molcel.2024.10.030
chicago: Ramadhin, Anisha R., Shun-Hsiao Lee, Di Zhou, Anita P Testa Salmazo, Camila
Gonzalo-Hansen, Marjolein van Sluis, Cindy M.A. Blom, et al. “STK19 Drives Transcription-Coupled
Repair by Stimulating Repair Complex Stability, RNA Pol II Ubiquitylation, and
TFIIH Recruitment.” Molecular Cell. Elsevier, 2024. https://doi.org/10.1016/j.molcel.2024.10.030.
ieee: A. R. Ramadhin et al., “STK19 drives transcription-coupled repair by
stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment,”
Molecular Cell, vol. 84, no. 24. Elsevier, p. 4740–4757.e12, 2024.
ista: Ramadhin AR, Lee S-H, Zhou D, Testa Salmazo AP, Gonzalo-Hansen C, van Sluis
M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen
W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA. 2024. STK19 drives
transcription-coupled repair by stimulating repair complex stability, RNA Pol
II ubiquitylation, and TFIIH recruitment. Molecular Cell. 84(24), 4740–4757.e12.
mla: Ramadhin, Anisha R., et al. “STK19 Drives Transcription-Coupled Repair by Stimulating
Repair Complex Stability, RNA Pol II Ubiquitylation, and TFIIH Recruitment.” Molecular
Cell, vol. 84, no. 24, Elsevier, 2024, p. 4740–4757.e12, doi:10.1016/j.molcel.2024.10.030.
short: A.R. Ramadhin, S.-H. Lee, D. Zhou, A.P. Testa Salmazo, C. Gonzalo-Hansen,
M. van Sluis, C.M.A. Blom, R.C. Janssens, A. Raams, D. Dekkers, K. Bezstarosti,
D. Slade, W. Vermeulen, A. Pines, J.A.A. Demmers, C. Bernecky, T.K. Sixma, J.A.
Marteijn, Molecular Cell 84 (2024) 4740–4757.e12.
date_created: 2024-11-15T12:12:54Z
date_published: 2024-12-19T00:00:00Z
date_updated: 2025-09-08T14:42:50Z
day: '19'
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- '570'
department:
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doi: 10.1016/j.molcel.2024.10.030
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quality_controlled: '1'
scopus_import: '1'
status: public
title: STK19 drives transcription-coupled repair by stimulating repair complex stability,
RNA Pol II ubiquitylation, and TFIIH recruitment
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
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year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18554'
abstract:
- lang: eng
text: We prove the Eigenstate Thermalization Hypothesis for general Wigner-type
matrices in the bulk of the self-consistent spectrum, with optimal control on
the fluctuations for obs ervables of arbitrary rank. As the main technical ingredient,
we prove rank-uniform optimal local laws for one and two resolvents of a Wigner-type
matrix with regular observables. Our results hold under very general conditions
on the variance profile, even allowing many vanishing entries, demonstrating that
Eigenstate Thermalization occurs robustly across a diverse class of random matrix
ensembles, for which the underlying quantum system has a non-trivial spatial structure.
acknowledgement: Open access funding provided by Institute of Science and Technology
(IST Austria).
article_number: '282'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Volodymyr
full_name: Riabov, Volodymyr
id: 1949f904-edfb-11eb-afb5-e2dfddabb93b
last_name: Riabov
citation:
ama: Erdös L, Riabov V. Eigenstate Thermalization Hypothesis for Wigner-type matrices.
Communications in Mathematical Physics. 2024;405(12). doi:10.1007/s00220-024-05143-y
apa: Erdös, L., & Riabov, V. (2024). Eigenstate Thermalization Hypothesis for
Wigner-type matrices. Communications in Mathematical Physics. Springer
Nature. https://doi.org/10.1007/s00220-024-05143-y
chicago: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis
for Wigner-Type Matrices.” Communications in Mathematical Physics. Springer
Nature, 2024. https://doi.org/10.1007/s00220-024-05143-y.
ieee: L. Erdös and V. Riabov, “Eigenstate Thermalization Hypothesis for Wigner-type
matrices,” Communications in Mathematical Physics, vol. 405, no. 12. Springer
Nature, 2024.
ista: Erdös L, Riabov V. 2024. Eigenstate Thermalization Hypothesis for Wigner-type
matrices. Communications in Mathematical Physics. 405(12), 282.
mla: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis
for Wigner-Type Matrices.” Communications in Mathematical Physics, vol.
405, no. 12, 282, Springer Nature, 2024, doi:10.1007/s00220-024-05143-y.
short: L. Erdös, V. Riabov, Communications in Mathematical Physics 405 (2024).
corr_author: '1'
date_created: 2024-11-17T23:01:46Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2026-04-07T12:32:19Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00220-024-05143-y
external_id:
arxiv:
- '2403.10359'
isi:
- '001348943900004'
pmid:
- '39526190'
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publisher: Springer Nature
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relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Eigenstate Thermalization Hypothesis for Wigner-type matrices
tmp:
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legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
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year: '2024'
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---
OA_place: publisher
OA_type: gold
_id: '18556'
abstract:
- lang: eng
text: Given a finite set, A ⊆ ℝ², and a subset, B ⊆ A, the MST-ratio is the combined
length of the minimum spanning trees of B and A⧵B divided by the length of the
minimum spanning tree of A. The question of the supremum, over all sets A, of
the maximum, over all subsets B, is related to the Steiner ratio, and we prove
this sup-max is between 2.154 and 2.427. Restricting ourselves to 2-dimensional
lattices, we prove that the sup-max is 2, while the inf-max is 1.25. By some margin
the most difficult of these results is the upper bound for the inf-max, which
we prove by showing that the hexagonal lattice cannot have MST-ratio larger than
1.25.
acknowledgement: This project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme,
grant no. 788183, from the Wittgenstein Prize, Austrian Science Fund (FWF), grant
no. Z 342-N31, and from the DFG Collaborative Research Center TRR 109, "Discretization
in Geometry and Dynamics", Austrian Science Fund (FWF), grant no. I 02979-N35.
alternative_title:
- LIPIcs
article_number: '3'
article_processing_charge: Yes
arxiv: 1
author:
- first_name: Sebastiano
full_name: Cultrera di Montesano, Sebastiano
id: 34D2A09C-F248-11E8-B48F-1D18A9856A87
last_name: Cultrera di Montesano
orcid: 0000-0001-6249-0832
- first_name: Ondrej
full_name: Draganov, Ondrej
id: 2B23F01E-F248-11E8-B48F-1D18A9856A87
last_name: Draganov
orcid: 0000-0003-0464-3823
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Morteza
full_name: Saghafian, Morteza
id: f86f7148-b140-11ec-9577-95435b8df824
last_name: Saghafian
citation:
ama: 'Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. The Euclidean
MST-ratio for bi-colored lattices. In: 32nd International Symposium on Graph
Drawing and Network Visualization. Vol 320. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik; 2024. doi:10.4230/LIPIcs.GD.2024.3'
apa: 'Cultrera di Montesano, S., Draganov, O., Edelsbrunner, H., & Saghafian,
M. (2024). The Euclidean MST-ratio for bi-colored lattices. In 32nd International
Symposium on Graph Drawing and Network Visualization (Vol. 320). Vienna, Austria:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.GD.2024.3'
chicago: Cultrera di Montesano, Sebastiano, Ondrej Draganov, Herbert Edelsbrunner,
and Morteza Saghafian. “The Euclidean MST-Ratio for Bi-Colored Lattices.” In 32nd
International Symposium on Graph Drawing and Network Visualization, Vol. 320.
Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. https://doi.org/10.4230/LIPIcs.GD.2024.3.
ieee: S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, and M. Saghafian,
“The Euclidean MST-ratio for bi-colored lattices,” in 32nd International Symposium
on Graph Drawing and Network Visualization, Vienna, Austria, 2024, vol. 320.
ista: 'Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. 2024. The
Euclidean MST-ratio for bi-colored lattices. 32nd International Symposium on Graph
Drawing and Network Visualization. GD: Graph Drawing and Network Visualization,
LIPIcs, vol. 320, 3.'
mla: Cultrera di Montesano, Sebastiano, et al. “The Euclidean MST-Ratio for Bi-Colored
Lattices.” 32nd International Symposium on Graph Drawing and Network Visualization,
vol. 320, 3, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:10.4230/LIPIcs.GD.2024.3.
short: S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, M. Saghafian, in:,
32nd International Symposium on Graph Drawing and Network Visualization, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2024.
conference:
end_date: 2024-09-20
location: Vienna, Austria
name: 'GD: Graph Drawing and Network Visualization'
start_date: 2024-09-18
corr_author: '1'
date_created: 2024-11-17T23:01:47Z
date_published: 2024-10-28T00:00:00Z
date_updated: 2025-12-02T13:50:50Z
day: '28'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.4230/LIPIcs.GD.2024.3
ec_funded: 1
external_id:
arxiv:
- '2403.10204'
isi:
- '001540278400001'
file:
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checksum: 5f9b35e115c3d375e99be78da9054cb4
content_type: application/pdf
creator: dernst
date_created: 2024-11-18T07:49:25Z
date_updated: 2024-11-18T07:49:25Z
file_id: '18560'
file_name: 2024_LIPIcs_CultreradiMontesano.pdf
file_size: 908541
relation: main_file
success: 1
file_date_updated: 2024-11-18T07:49:25Z
fulldoi: https://doi.org/10.4230/LIPIcs.GD.2024.3
has_accepted_license: '1'
intvolume: ' 320'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
publication: 32nd International Symposium on Graph Drawing and Network Visualization
publication_identifier:
isbn:
- '9783959773430'
issn:
- 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Euclidean MST-ratio for bi-colored lattices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 320
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '18559'
abstract:
- lang: eng
text: We prove a 1973 conjecture due to Erdős on the existence of Steiner triple
systems with arbitrarily high girth.
acknowledgement: Sah and Sawhney were supported by NSF Graduate Research Fellowship
Program DGE1745302. Sah was supported by the PD Soros Fellowship. Simkin was supported
by the Center of Mathematical Sciences and Applications at Harvard University.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Matthew Alan
full_name: Kwan, Matthew Alan
id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
last_name: Kwan
orcid: 0000-0002-4003-7567
- first_name: Ashwin
full_name: Sah, Ashwin
last_name: Sah
- first_name: Mehtaab
full_name: Sawhney, Mehtaab
last_name: Sawhney
- first_name: Michael
full_name: Simkin, Michael
last_name: Simkin
citation:
ama: Kwan MA, Sah A, Sawhney M, Simkin M. High-girth Steiner triple systems. Annals
of Mathematics. 2024;200(3):1059-1156. doi:10.4007/annals.2024.200.3.4
apa: Kwan, M. A., Sah, A., Sawhney, M., & Simkin, M. (2024). High-girth Steiner
triple systems. Annals of Mathematics. Princeton University. https://doi.org/10.4007/annals.2024.200.3.4
chicago: Kwan, Matthew Alan, Ashwin Sah, Mehtaab Sawhney, and Michael Simkin. “High-Girth
Steiner Triple Systems.” Annals of Mathematics. Princeton University, 2024.
https://doi.org/10.4007/annals.2024.200.3.4.
ieee: M. A. Kwan, A. Sah, M. Sawhney, and M. Simkin, “High-girth Steiner triple
systems,” Annals of Mathematics, vol. 200, no. 3. Princeton University,
pp. 1059–1156, 2024.
ista: Kwan MA, Sah A, Sawhney M, Simkin M. 2024. High-girth Steiner triple systems.
Annals of Mathematics. 200(3), 1059–1156.
mla: Kwan, Matthew Alan, et al. “High-Girth Steiner Triple Systems.” Annals of
Mathematics, vol. 200, no. 3, Princeton University, 2024, pp. 1059–156, doi:10.4007/annals.2024.200.3.4.
short: M.A. Kwan, A. Sah, M. Sawhney, M. Simkin, Annals of Mathematics 200 (2024)
1059–1156.
corr_author: '1'
date_created: 2024-11-17T23:01:48Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2025-09-08T14:40:55Z
day: '01'
department:
- _id: MaKw
doi: 10.4007/annals.2024.200.3.4
external_id:
arxiv:
- '2201.04554'
isi:
- '001366233800004'
fulldoi: https://doi.org/10.4007/annals.2024.200.3.4
intvolume: ' 200'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2201.04554
month: '11'
oa: 1
oa_version: Preprint
page: 1059-1156
publication: Annals of Mathematics
publication_identifier:
eissn:
- 1939-8980
issn:
- 0003-486X
publication_status: published
publisher: Princeton University
quality_controlled: '1'
scopus_import: '1'
status: public
title: High-girth Steiner triple systems
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 200
year: '2024'
...
---
OA_type: closed access
_id: '18563'
abstract:
- lang: eng
text: I give a personal account about the wave of new research activities that rose
in the 1990s on the specification, verification, and control of real-time systems.
acknowledgement: I thank all my collaborators over the years. None of the mentioned
contributions would have been possible without them. I also apologize for all omissions.
The selection of contributions in this essay reflects primarily my personal involvement
rather than any measure of importance.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000-0002-2985-7724
citation:
ama: 'Henzinger TA. Reminiscences of a Real-Time Researcher. In: Graf S, Pettersson
P, Steffen B, eds. Real Time and Such. Vol 15230. LNCS. Cham: Springer
Nature; 2024:154-164. doi:10.1007/978-3-031-73751-0_12'
apa: 'Henzinger, T. A. (2024). Reminiscences of a Real-Time Researcher. In S. Graf,
P. Pettersson, & B. Steffen (Eds.), Real Time and Such (Vol. 15230,
pp. 154–164). Cham: Springer Nature. https://doi.org/10.1007/978-3-031-73751-0_12'
chicago: 'Henzinger, Thomas A. “Reminiscences of a Real-Time Researcher.” In Real
Time and Such, edited by Susanne Graf, Paul Pettersson, and Bernhard Steffen,
15230:154–64. LNCS. Cham: Springer Nature, 2024. https://doi.org/10.1007/978-3-031-73751-0_12.'
ieee: 'T. A. Henzinger, “Reminiscences of a Real-Time Researcher,” in Real Time
and Such, vol. 15230, S. Graf, P. Pettersson, and B. Steffen, Eds. Cham: Springer
Nature, 2024, pp. 154–164.'
ista: 'Henzinger TA. 2024.Reminiscences of a Real-Time Researcher. In: Real Time
and Such. LNCS, vol. 15230, 154–164.'
mla: Henzinger, Thomas A. “Reminiscences of a Real-Time Researcher.” Real Time
and Such, edited by Susanne Graf et al., vol. 15230, Springer Nature, 2024,
pp. 154–64, doi:10.1007/978-3-031-73751-0_12.
short: T.A. Henzinger, in:, S. Graf, P. Pettersson, B. Steffen (Eds.), Real Time
and Such, Springer Nature, Cham, 2024, pp. 154–164.
corr_author: '1'
date_created: 2024-11-18T09:10:06Z
date_published: 2024-10-23T00:00:00Z
date_updated: 2025-08-05T12:19:50Z
day: '23'
department:
- _id: ToHe
doi: 10.1007/978-3-031-73751-0_12
editor:
- first_name: Susanne
full_name: Graf, Susanne
last_name: Graf
- first_name: Paul
full_name: Pettersson, Paul
last_name: Pettersson
- first_name: Bernhard
full_name: Steffen, Bernhard
last_name: Steffen
fulldoi: https://doi.org/10.1007/978-3-031-73751-0_12
intvolume: ' 15230'
language:
- iso: eng
month: '10'
oa_version: None
page: 154-164
place: Cham
publication: Real Time and Such
publication_identifier:
eisbn:
- '9783031737510'
eissn:
- 1611-3349
isbn:
- '9783031737503'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: Reminiscences of a Real-Time Researcher
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15230
year: '2024'
...
---
OA_place: publisher
_id: '18568'
abstract:
- lang: eng
text: "Locomotion is ubiquitous in the animal kingdom because an animal's survival
depends on its ability to navigate its environment to find food, avoid predators
and locate potential mates. These behaviours require control mechanisms that can
extract information from the environment, particularly visual cues. Selective
evolutionary pressures have thus refined such visuomotor transformations in a
species-specific manner to meet the specific ecological and ethological challenges
of each organism. However, a common challenge across organisms as visual information
processing\r\nbecomes increasingly detailed is the mechanisms required to synthesise
disparate pieces of information into a coherent percept or unified picture of
the world. In this thesis, I investigate how disparate visual information is combined
in the brain of Drosophila melanogaster to effectively guide locomotion.\r\nFor
this, I first designed and built a behavioural setup to record locomotion and
present visual stimuli to freely-walking fruit flies in a closed-loop manner.
This setup allowed the investigation of innate visually-guided behaviours, including
the optomotor reflex and courtship.\r\nSecond, taking advantage of my system I
investigated the optomotor response, a reflexive visual stabilisation behaviour
in which flies turn in the direction of global motion to minimise retinal slip.
This behaviour is thought to be mediated by Lobula plate tangential cells (LPTCs);
a complex network of optic-flow-sensitive neurons essential for self-motion estimation.
Using a novel genetic mutant, I demonstrate that electrical coupling between two
LPTC subtypes, contralateral HS and H2 neurons, regulates the balance between
smooth optomotor turning and saccadic anti-optomotor responses. These findings
underscore the critical role of binocular motion cue integration in guiding course
control. Finally, I developed a novel behavioural paradigm in which a sexually
aroused male fruit fly is presented with an optomotor distractor. This setup creates
competition between two visual behaviours, courtship tracking and the optomotor
response, enabling me to explore how the visual system resolves this conflict.
In this setting, males\r\nengaged in courtship selectively suppress their optomotor
response based on the female's location. Furthermore, when this experiment is
replicated with an “artificial female”, optogenetically aroused males alternate
between tracking and optomotor responses. The probability and dynamics of this
switching are determined by the relative strengths of the two competing stimuli.
In summary, the results presented in this thesis explore two mechanisms – integration
and competition - through which visual information is combined in the brain of
the fruit fly to drive locomotion."
acknowledged_ssus:
- _id: M-Shop
acknowledgement: I am incredibly thankful for the outstanding support provided by
ISTA, especially the Machine Shop team, who made conducting research much easier
and more efficient. I am also grateful for the funding provided by European Union’s
Horizon 2020 research and innovation program under the Marie Skłodowska-Curie programme
(665385) and The German Research Foundation grant DFG (SPP2205) “Evolutionary optimization
of neuronal processing”.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
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full_name: Satapathy, Roshan K
id: 46046B7A-F248-11E8-B48F-1D18A9856A87
last_name: Satapathy
orcid: 0009-0006-2974-5075
citation:
ama: Satapathy RK. Mechanisms of visual integration and competition in innate behaviours
in Drosophila melanogaster. 2024. doi:10.15479/at:ista:18568
apa: Satapathy, R. K. (2024). Mechanisms of visual integration and competition
in innate behaviours in Drosophila melanogaster. Institute of Science and
Technology Austria. https://doi.org/10.15479/at:ista:18568
chicago: Satapathy, Roshan K. “Mechanisms of Visual Integration and Competition
in Innate Behaviours in Drosophila Melanogaster.” Institute of Science and Technology
Austria, 2024. https://doi.org/10.15479/at:ista:18568.
ieee: R. K. Satapathy, “Mechanisms of visual integration and competition in innate
behaviours in Drosophila melanogaster,” Institute of Science and Technology Austria,
2024.
ista: Satapathy RK. 2024. Mechanisms of visual integration and competition in innate
behaviours in Drosophila melanogaster. Institute of Science and Technology Austria.
mla: Satapathy, Roshan K. Mechanisms of Visual Integration and Competition in
Innate Behaviours in Drosophila Melanogaster. Institute of Science and Technology
Austria, 2024, doi:10.15479/at:ista:18568.
short: R.K. Satapathy, Mechanisms of Visual Integration and Competition in Innate
Behaviours in Drosophila Melanogaster, Institute of Science and Technology Austria,
2024.
corr_author: '1'
date_created: 2024-11-19T12:34:30Z
date_published: 2024-11-20T00:00:00Z
date_updated: 2026-04-07T13:00:36Z
day: '20'
ddc:
- '573'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaJö
doi: 10.15479/at:ista:18568
ec_funded: 1
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has_accepted_license: '1'
language:
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license: https://creativecommons.org/licenses/by-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: '114'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_identifier:
isbn:
- 978-3-99078-047-3
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '18444'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Maximilian A
full_name: Jösch, Maximilian A
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
title: Mechanisms of visual integration and competition in innate behaviours in Drosophila
melanogaster
tmp:
image: /images/cc_by_sa.png
legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
BY-SA 4.0)
short: CC BY-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
OA_place: publisher
_id: '18579'
abstract:
- lang: eng
text: 'Electrophysiological, calcium two-photon recordings and behavioral data for
Vega-Zuniga et al. Relevant information can be found in the ''README.txt'' files. '
acknowledged_ssus:
- _id: ScienComp
- _id: PreCl
- _id: M-Shop
- _id: Bio
- _id: LifeSc
acknowledgement: Freyja Lange, Michael Schunn, and Todor Asenov
article_processing_charge: No
author:
- first_name: Tomas A
full_name: Vega Zuniga, Tomas A
id: 2E7C4E78-F248-11E8-B48F-1D18A9856A87
last_name: Vega Zuniga
- first_name: Anton L
full_name: Sumser, Anton L
id: 3320A096-F248-11E8-B48F-1D18A9856A87
last_name: Sumser
orcid: 0000-0002-4792-1881
- first_name: Olga
full_name: Symonova, Olga
id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
last_name: Symonova
orcid: 0000-0003-2012-9947
- first_name: Peter
full_name: Koppensteiner, Peter
id: 3B8B25A8-F248-11E8-B48F-1D18A9856A87
last_name: Koppensteiner
orcid: 0000-0002-3509-1948
- first_name: Florian
full_name: Schmidt, Florian
id: A2EF226A-AF19-11E9-924C-0525E6697425
last_name: Schmidt
- first_name: Maximilian A
full_name: Jösch, Maximilian A
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
citation:
ama: Vega Zuniga TA, Sumser AL, Symonova O, Koppensteiner P, Schmidt F, Jösch MA.
A thalamic hub-and-spoke network enables visual perception during action by coordinating
visuomotor dynamics. 2024. doi:10.15479/AT:ISTA:18579
apa: Vega Zuniga, T. A., Sumser, A. L., Symonova, O., Koppensteiner, P., Schmidt,
F., & Jösch, M. A. (2024). A thalamic hub-and-spoke network enables visual
perception during action by coordinating visuomotor dynamics. Institute of Science
and Technology Austria. https://doi.org/10.15479/AT:ISTA:18579
chicago: Vega Zuniga, Tomas A, Anton L Sumser, Olga Symonova, Peter Koppensteiner,
Florian Schmidt, and Maximilian A Jösch. “A Thalamic Hub-and-Spoke Network Enables
Visual Perception during Action by Coordinating Visuomotor Dynamics.” Institute
of Science and Technology Austria, 2024. https://doi.org/10.15479/AT:ISTA:18579.
ieee: T. A. Vega Zuniga, A. L. Sumser, O. Symonova, P. Koppensteiner, F. Schmidt,
and M. A. Jösch, “A thalamic hub-and-spoke network enables visual perception during
action by coordinating visuomotor dynamics.” Institute of Science and Technology
Austria, 2024.
ista: Vega Zuniga TA, Sumser AL, Symonova O, Koppensteiner P, Schmidt F, Jösch MA.
2024. A thalamic hub-and-spoke network enables visual perception during action
by coordinating visuomotor dynamics, Institute of Science and Technology Austria,
10.15479/AT:ISTA:18579.
mla: Vega Zuniga, Tomas A., et al. A Thalamic Hub-and-Spoke Network Enables Visual
Perception during Action by Coordinating Visuomotor Dynamics. Institute of
Science and Technology Austria, 2024, doi:10.15479/AT:ISTA:18579.
short: T.A. Vega Zuniga, A.L. Sumser, O. Symonova, P. Koppensteiner, F. Schmidt,
M.A. Jösch, (2024).
corr_author: '1'
date_created: 2024-11-22T13:48:12Z
date_published: 2024-12-09T00:00:00Z
date_updated: 2026-06-18T18:12:08Z
day: '09'
ddc:
- '570'
department:
- _id: MaJö
doi: 10.15479/AT:ISTA:18579
ec_funded: 1
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month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 264FEA02-B435-11E9-9278-68D0E5697425
grant_number: ALTF 1098-2017
name: Connecting sensory with motor processing in the superior colliculus
- _id: 266D407A-B435-11E9-9278-68D0E5697425
grant_number: LT000256
name: Neuronal networks of salience and spatial detection in the murine superior
colliculus
- _id: 2634E9D2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '756502'
name: Circuits of Visual Attention
- _id: bdaf81a8-d553-11ed-ba76-c95961984540
grant_number: '101086580'
name: 'Action Selection in the Midbrain: Neuromodulation of Visuomotor Senses'
publisher: Institute of Science and Technology Austria
related_material:
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status: public
status: public
title: A thalamic hub-and-spoke network enables visual perception during action by
coordinating visuomotor dynamics
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18581'
abstract:
- lang: eng
text: "Background: Human induced pluripotent stem cells represent a scalable source
of youthful tissue progenitors and secretomes for regenerative therapies. The
aim of our study was to investigate the potential of conditioned medium (CM) from
hiPSC-mesenchymal progenitors (hiPSC-MPs) to stimulate osteogenic differentiation
of human bone marrow-derived mesenchymal stromal cells (MSCs). We also investigated
whether prolonged cultivation or osteogenic pre-differentiation of hiPSC-MPs could
enhance the stimulatory activity of CM.\r\nMethods: MSCs were isolated from 13
donors (age 20–90 years). CM derived from hiPSC-MPs was added to the MSC cultures
and the effects on proliferation and osteogenic differentiation were examined
after 14 days and 6 weeks. The stimulatory activity of hiPSC-MP-CM was compared
with the activity of MSC-derived CM and with the activity of CM prepared from
hiPSC-MPs pre-cultured in growth or osteogenic medium for 14 days. Comparative
proteomic analysis of CM was performed to gain insight into the molecular components
responsible for the stimulatory activity.\r\nResults: Primary bone marrow-derived
MSC exhibited variability, with a tendency towards lower proliferation and tri-lineage
differentiation in older donors. hiPSC-MP-CM increased the proliferation and alkaline
phosphatase activity of MSC from several adult/aged donors after 14 days of continuous
supplementation under osteogenic conditions. However, CM supplementation failed
to improve the mineralization of MSC pellets after 6 weeks under osteogenic conditions.
hiPSC-MP-CM showed greater enhancement of proliferation and ALP activity than
CM derived from bone marrow-derived MSCs. Moreover, 14-day cultivation but not
osteogenic pre-differentiation of hiPSC-MPs strongly enhanced CM stimulatory activity.
Quantitative proteomic analysis of d14-CM revealed a distinct profile of components
that formed a highly interconnected associations network with two clusters, one
functionally associated with binding and organization of actin/cytoskeletal components
and the other with structural constituents of the extracellular matrix, collagen,
and growth factor binding. Several hub proteins were identified that were reported
to have functions in cell-extracellular matrix interaction, osteogenic differentiation
and development.\r\nConclusions: Our data show that hiPSC-MP-CM enhances early
osteogenic differentiation of human bone marrow-derived MSCs and that prolonged
cultivation of hiPSC-MPs enhances CM-stimulatory activity. Proteomic analysis
of the upregulated protein components provides the basis for further optimization
of hiPSC-MP-CM for bone regenerative therapies."
acknowledgement: "We thank the personnel of the Lorenz-Böhler-Unfallkrankenhaus for
providing the human tissue waste for primary cell isolation and the New York Stem
Cell Foundation Research Institute for providing the human induced pluripotent stem
cell line 1013 A and its mesenchymal progenitors. We also thank all our colleagues
at the Ludwig Boltzmann Institute for Traumatology for their suggestions and ongoing
support of the project. InstaText writing tool (https://instatext.io) was used to
edit the English language of the final manuscript.\r\nThis work has received funding
from the European Union’s Horizon 2020 research and innovation program under the
Marie Sklodowska-Curie actions (grant agreement No. 657716) and the Transforming
European Industry call H2020-NMBP-TRIND-2020 (grant agreement No. 953134), as well
as by the FFG Industrienahe Dissertation program (grant agreement No. 867803 and
853056), the FEMtech Praktika program (grant agreement No. 852154, 868917 and 877951)
and the Production of the Future program (grant agreement No. 877452)."
article_number: '434'
article_processing_charge: Yes
article_type: original
author:
- first_name: Darja
full_name: Marolt Presen, Darja
last_name: Marolt Presen
- first_name: Vanessa
full_name: Goeschl, Vanessa
last_name: Goeschl
- first_name: Dominik
full_name: Hanetseder, Dominik
last_name: Hanetseder
- first_name: Laura
full_name: Ogrin, Laura
last_name: Ogrin
- first_name: Alexandra Larissa
full_name: Stetco, Alexandra Larissa
last_name: Stetco
- first_name: Anja
full_name: Tansek, Anja
last_name: Tansek
- first_name: Laura
full_name: Pozenel, Laura
last_name: Pozenel
- first_name: Bella
full_name: Bruszel, Bella
id: 70abbbb3-88ea-11ec-8e0a-e8c939944834
last_name: Bruszel
- first_name: Goran
full_name: Mitulovic, Goran
last_name: Mitulovic
- first_name: Johannes
full_name: Oesterreicher, Johannes
last_name: Oesterreicher
- first_name: Johannes
full_name: Zipperle, Johannes
last_name: Zipperle
- first_name: Barbara
full_name: Schaedl, Barbara
last_name: Schaedl
- first_name: Wolfgang
full_name: Holnthoner, Wolfgang
last_name: Holnthoner
- first_name: Johannes
full_name: Grillari, Johannes
last_name: Grillari
- first_name: Heinz
full_name: Redl, Heinz
last_name: Redl
citation:
ama: Marolt Presen D, Goeschl V, Hanetseder D, et al. Prolonged cultivation enhances
the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium.
Stem Cell Research and Therapy. 2024;15. doi:10.1186/s13287-024-03960-5
apa: Marolt Presen, D., Goeschl, V., Hanetseder, D., Ogrin, L., Stetco, A. L., Tansek,
A., … Redl, H. (2024). Prolonged cultivation enhances the stimulatory activity
of hiPSC mesenchymal progenitor-derived conditioned medium. Stem Cell Research
and Therapy. Springer Nature. https://doi.org/10.1186/s13287-024-03960-5
chicago: Marolt Presen, Darja, Vanessa Goeschl, Dominik Hanetseder, Laura Ogrin,
Alexandra Larissa Stetco, Anja Tansek, Laura Pozenel, et al. “Prolonged Cultivation
Enhances the Stimulatory Activity of HiPSC Mesenchymal Progenitor-Derived Conditioned
Medium.” Stem Cell Research and Therapy. Springer Nature, 2024. https://doi.org/10.1186/s13287-024-03960-5.
ieee: D. Marolt Presen et al., “Prolonged cultivation enhances the stimulatory
activity of hiPSC mesenchymal progenitor-derived conditioned medium,” Stem
Cell Research and Therapy, vol. 15. Springer Nature, 2024.
ista: Marolt Presen D, Goeschl V, Hanetseder D, Ogrin L, Stetco AL, Tansek A, Pozenel
L, Bruszel B, Mitulovic G, Oesterreicher J, Zipperle J, Schaedl B, Holnthoner
W, Grillari J, Redl H. 2024. Prolonged cultivation enhances the stimulatory activity
of hiPSC mesenchymal progenitor-derived conditioned medium. Stem Cell Research
and Therapy. 15, 434.
mla: Marolt Presen, Darja, et al. “Prolonged Cultivation Enhances the Stimulatory
Activity of HiPSC Mesenchymal Progenitor-Derived Conditioned Medium.” Stem
Cell Research and Therapy, vol. 15, 434, Springer Nature, 2024, doi:10.1186/s13287-024-03960-5.
short: D. Marolt Presen, V. Goeschl, D. Hanetseder, L. Ogrin, A.L. Stetco, A. Tansek,
L. Pozenel, B. Bruszel, G. Mitulovic, J. Oesterreicher, J. Zipperle, B. Schaedl,
W. Holnthoner, J. Grillari, H. Redl, Stem Cell Research and Therapy 15 (2024).
date_created: 2024-11-24T23:01:47Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-09-09T11:41:12Z
day: '01'
ddc:
- '570'
department:
- _id: LifeSc
doi: 10.1186/s13287-024-03960-5
external_id:
isi:
- '001356479400001'
pmid:
- '39551765'
file:
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checksum: 91edba8edde30d781dce89fdd5cadc39
content_type: application/pdf
creator: dernst
date_created: 2024-12-10T08:28:17Z
date_updated: 2024-12-10T08:28:17Z
file_id: '18641'
file_name: 2024_StemCellResearch_Presen.pdf
file_size: 6690494
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file_date_updated: 2024-12-10T08:28:17Z
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intvolume: ' 15'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Stem Cell Research and Therapy
publication_identifier:
eissn:
- 1757-6512
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal
progenitor-derived conditioned medium
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18582'
abstract:
- lang: eng
text: Identification of PIN exporters for auxin, the major coordinative signal in
plants, some 25 years ago, signifies a landmark in our understanding of plant-specific
mechanisms underlying development and adaptation. Auxin is directionally transported
throughout the plant body; a unique feature already envisioned by Darwin and solidified
by PINs’ discovery and characterization. The PIN-based auxin distribution network
with its complex regulations of PIN expression, localization and activity turned
out to underlie a remarkable multitude of developmental processes and represents
means to integrate endogenous and environmental signals. Given the recent anniversary,
we here summarize past and current developments in this exciting field.
acknowledgement: We gratefully acknowledge Leo Gälweiler for authorizing his PIN1
story. We would like to thank Yuanrong Pei for invaluable help with preparing figures.
Work in the lab of C.L. is supported by grants from the Austrian Science Fund (PAT
8419423) and by the Gesellschaft für Forschungsförderung Niederösterreich m.b.H.
(FTI19-008). The lab of J.F. is supported by the Austrian Science Fund (I 6123-B
and P 37051-B).
article_number: '9904'
article_processing_charge: Yes
article_type: original
author:
- first_name: Christian
full_name: Luschnig, Christian
last_name: Luschnig
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Luschnig C, Friml J. Over 25 years of decrypting PIN-mediated plant development.
Nature Communications. 2024;15. doi:10.1038/s41467-024-54240-y
apa: Luschnig, C., & Friml, J. (2024). Over 25 years of decrypting PIN-mediated
plant development. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-024-54240-y
chicago: Luschnig, Christian, and Jiří Friml. “Over 25 Years of Decrypting PIN-Mediated
Plant Development.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-54240-y.
ieee: C. Luschnig and J. Friml, “Over 25 years of decrypting PIN-mediated plant
development,” Nature Communications, vol. 15. Springer Nature, 2024.
ista: Luschnig C, Friml J. 2024. Over 25 years of decrypting PIN-mediated plant
development. Nature Communications. 15, 9904.
mla: Luschnig, Christian, and Jiří Friml. “Over 25 Years of Decrypting PIN-Mediated
Plant Development.” Nature Communications, vol. 15, 9904, Springer Nature,
2024, doi:10.1038/s41467-024-54240-y.
short: C. Luschnig, J. Friml, Nature Communications 15 (2024).
corr_author: '1'
date_created: 2024-11-24T23:01:48Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-09-08T14:53:48Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41467-024-54240-y
external_id:
isi:
- '001356232600004'
pmid:
- '39548100'
file:
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content_type: application/pdf
creator: dernst
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file_name: 2024_NatureComm_Luschnig.pdf
file_size: 1426555
relation: main_file
success: 1
file_date_updated: 2024-12-03T14:10:54Z
fulldoi: https://doi.org/10.1038/s41467-024-54240-y
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: bd76d395-d553-11ed-ba76-f678c14f9033
grant_number: I06123
name: Peptide receptors for auxin canalization in Arabidopsis
- _id: 7bcece63-9f16-11ee-852c-ae94e099eeb6
grant_number: P37051
name: Guanylate cyclase activity of TIR1/AFBs auxin receptors
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Over 25 years of decrypting PIN-mediated plant development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18583'
abstract:
- lang: eng
text: "There are a number of well-known problems and conjectures about partitioning
graphs to satisfy local constraints. For example, the majority colouring conjecture
of Kreutzer, Oum, Seymour, van der Zypen and Wood states that every directed graph
has a 3-colouring such that for every vertex v, at most half of the out-neighbours
of v have the same colour as \r\n. As another example, the internal partition
conjecture, due to DeVos and to Ban and Linial, states that for every d, all but
finitely many d-regular graphs have a partition into two non-empty parts such
that for every vertex v, at least half of the neighbours of v lie in the same
part as v. We prove several results in this spirit: in particular, two of our
results are that the majority colouring conjecture holds for Erdős–Rényi random
directed graphs (of any density), and that the internal partition conjecture holds
if we permit a tiny number of ‘exceptional vertices’. Our proofs involve a variety
of techniques, including several different methods to analyse random recolouring
processes. One highlight is a personality-changing scheme: we ‘forget’ certain
information based on the state of a Markov chain, giving us more independence
to work with."
acknowledgement: "We are grateful to the anonymous referees for their thorough reading
of the paper, and for many suggestions which have improved the exposition throughout.\r\n\r\nMichael
Anastos was supported by the European Union's Horizon 2020 research and innovation
programme under the Marie Skłodowska-Curie grant agreement No. 101034413. Matthew
Kwan was supported by ERC Starting Grant ‘RANDSTRUCT’ No. 101076777, also funded
by the European Union image. Mihyun Kang was supported in part by the Austrian Science
Fund (FWF) [10.55776/I6502]. For the purpose of open access, the authors have applied
a CC-BY public copyright licence to any Author Accepted Manuscript version arising
from this submission."
article_number: e70010
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author:
- first_name: Michael
full_name: Anastos, Michael
id: 0b2a4358-bb35-11ec-b7b9-e3279b593dbb
last_name: Anastos
- first_name: Oliver
full_name: Cooley, Oliver
id: 43f4ddd0-a46b-11ec-8df6-ef3703bd721d
last_name: Cooley
- first_name: Mihyun
full_name: Kang, Mihyun
last_name: Kang
- first_name: Matthew Alan
full_name: Kwan, Matthew Alan
id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
last_name: Kwan
orcid: 0000-0002-4003-7567
citation:
ama: Anastos M, Cooley O, Kang M, Kwan MA. Partitioning problems via random processes.
Journal of the London Mathematical Society. 2024;110(6). doi:10.1112/jlms.70010
apa: Anastos, M., Cooley, O., Kang, M., & Kwan, M. A. (2024). Partitioning problems
via random processes. Journal of the London Mathematical Society. Wiley.
https://doi.org/10.1112/jlms.70010
chicago: Anastos, Michael, Oliver Cooley, Mihyun Kang, and Matthew Alan Kwan. “Partitioning
Problems via Random Processes.” Journal of the London Mathematical Society.
Wiley, 2024. https://doi.org/10.1112/jlms.70010.
ieee: M. Anastos, O. Cooley, M. Kang, and M. A. Kwan, “Partitioning problems via
random processes,” Journal of the London Mathematical Society, vol. 110,
no. 6. Wiley, 2024.
ista: Anastos M, Cooley O, Kang M, Kwan MA. 2024. Partitioning problems via random
processes. Journal of the London Mathematical Society. 110(6), e70010.
mla: Anastos, Michael, et al. “Partitioning Problems via Random Processes.” Journal
of the London Mathematical Society, vol. 110, no. 6, e70010, Wiley, 2024,
doi:10.1112/jlms.70010.
short: M. Anastos, O. Cooley, M. Kang, M.A. Kwan, Journal of the London Mathematical
Society 110 (2024).
corr_author: '1'
date_created: 2024-11-24T23:01:48Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-12-02T13:52:26Z
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doi: 10.1112/jlms.70010
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title: Partitioning problems via random processes
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