---
_id: '18066'
abstract:
- lang: eng
  text: 'Graph games lie at the algorithmic core of many automated design problems
    in computer science. These are games usually played between two players on a given
    graph, where the players keep moving a token along the edges according to pre-determined
    rules (turn-based, concurrent, etc.), and the winner is decided based on the infinite
    path (aka play) traversed by the token from a given initial position. In bidding
    games, the players initially get some monetary budgets which they need to use
    to bid for the privilege of moving the token at each step. Each round of bidding
    affects the players'' available budgets, which is the only form of update that
    the budgets experience. We introduce bidding games with charging where the players
    can additionally improve their budgets during the game by collecting vertex-dependent
    monetary rewards, aka the "charges." Unlike traditional bidding games (where all
    charges are zero), bidding games with charging allow non-trivial recurrent behaviors.
    For example, a reachability objective may require multiple detours to vertices
    with high charges to earn additional budget. We show that, nonetheless, the central
    property of traditional bidding games generalizes to bidding games with charging:
    For each vertex there exists a threshold ratio, which is the necessary and sufficient
    fraction of the total budget for winning the game from that vertex. While the
    thresholds of traditional bidding games correspond to unique fixed points of linear
    systems of equations, in games with charging, these fixed points are no longer
    unique. This significantly complicates the proof of existence and the algorithmic
    computation of thresholds for infinite-duration objectives. We also provide the
    lower complexity bounds for computing thresholds for Rabin and Streett objectives,
    which are the first known lower bounds in any form of bidding games (with or without
    charging), and we solve the following repair problem for safety and reachability
    games that have unsatisfiable objectives: Can we distribute a given amount of
    charge to the players in a way such that the objective can be satisfied?'
acknowledgement: This work was supported in part by the ERC projects ERC-2020-AdG
  101020093 and CoG 863818 (ForM-SMArt) and by ISF grant no. 1679/21.
alternative_title:
- LIPIcs
article_number: '8'
article_processing_charge: Yes
arxiv: 1
author:
- first_name: Guy
  full_name: Avni, Guy
  id: 463C8BC2-F248-11E8-B48F-1D18A9856A87
  last_name: Avni
  orcid: 0000-0001-5588-8287
- first_name: Ehsan Kafshdar
  full_name: Goharshady, Ehsan Kafshdar
  last_name: Goharshady
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Kaushik
  full_name: Mallik, Kaushik
  id: 0834ff3c-6d72-11ec-94e0-b5b0a4fb8598
  last_name: Mallik
  orcid: 0000-0001-9864-7475
citation:
  ama: 'Avni G, Goharshady EK, Henzinger TA, Mallik K. Bidding games with charging.
    In: <i>35th International Conference on Concurrency Theory</i>. Vol 311. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.8">10.4230/LIPIcs.CONCUR.2024.8</a>'
  apa: 'Avni, G., Goharshady, E. K., Henzinger, T. A., &#38; Mallik, K. (2024). Bidding
    games with charging. In <i>35th International Conference on Concurrency Theory</i>
    (Vol. 311). Calgary, Canada: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
    <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.8">https://doi.org/10.4230/LIPIcs.CONCUR.2024.8</a>'
  chicago: Avni, Guy, Ehsan Kafshdar Goharshady, Thomas A Henzinger, and Kaushik Mallik.
    “Bidding Games with Charging.” In <i>35th International Conference on Concurrency
    Theory</i>, Vol. 311. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024.
    <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.8">https://doi.org/10.4230/LIPIcs.CONCUR.2024.8</a>.
  ieee: G. Avni, E. K. Goharshady, T. A. Henzinger, and K. Mallik, “Bidding games
    with charging,” in <i>35th International Conference on Concurrency Theory</i>,
    Calgary, Canada, 2024, vol. 311.
  ista: 'Avni G, Goharshady EK, Henzinger TA, Mallik K. 2024. Bidding games with charging.
    35th International Conference on Concurrency Theory. CONCUR: Conference on Concurrency
    Theory, LIPIcs, vol. 311, 8.'
  mla: Avni, Guy, et al. “Bidding Games with Charging.” <i>35th International Conference
    on Concurrency Theory</i>, vol. 311, 8, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2024, doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.8">10.4230/LIPIcs.CONCUR.2024.8</a>.
  short: G. Avni, E.K. Goharshady, T.A. Henzinger, K. Mallik, in:, 35th International
    Conference on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2024.
conference:
  end_date: 2024-09-13
  location: Calgary, Canada
  name: 'CONCUR: Conference on Concurrency Theory'
  start_date: 2024-09-09
corr_author: '1'
date_created: 2024-09-15T22:01:39Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-12-02T13:46:11Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.CONCUR.2024.8
ec_funded: 1
external_id:
  arxiv:
  - '2407.06288'
  isi:
  - '001556847400008'
file:
- access_level: open_access
  checksum: cb6f2254b84922cd7bf224f550b73f4a
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-17T09:35:03Z
  date_updated: 2024-09-17T09:35:03Z
  file_id: '18083'
  file_name: 2024_LIPICS_Avni.pdf
  file_size: 854430
  relation: main_file
  success: 1
file_date_updated: 2024-09-17T09:35:03Z
has_accepted_license: '1'
intvolume: '       311'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: 35th International Conference on Concurrency Theory
publication_identifier:
  isbn:
  - '9783959773393'
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bidding games with charging
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 311
year: '2024'
...
---
_id: '18067'
abstract:
- lang: eng
  text: "An automaton \U0001D49C is history-deterministic if its nondeterminism can
    be resolved on the fly, only using the prefix of the word read so far. This mild
    form of nondeterminism has attracted particular attention for its applications
    in synthesis problems. An automaton \U0001D49C is guidable with respect to a class
    C of automata if it can fairly simulate every automaton in C, whose language is
    contained in that of \U0001D49C. In other words, guidable automata are those for
    which inclusion and simulation coincide, making them particularly interesting
    for model-checking. We study the connection between these two notions, and specifically
    the question of when they coincide. For classes of automata on which they do,
    deciding guidability, an otherwise challenging decision problem, reduces to deciding
    history-determinism, a problem that is starting to be well-understood for many
    classes. We provide a selection of sufficient criteria for a class of automata
    to guarantee the coincidence of the notions, and use them to show that the notions
    coincide for the most common automata classes, among which are ω-regular automata
    and many infinite-state automata with safety and reachability acceptance conditions,
    including vector addition systems with states, one-counter nets, pushdown-, Parikh-,
    and timed-automata. We also demonstrate that history-determinism and guidability
    do not always coincide, for example, for the classes of timed automata with a
    fixed number of clocks."
acknowledgement: "Udi Boker: Israel Science Foundation grant 2410/22\r\nThomas A.
  Henzinger: ERC-2020-AdG 101020093 (VAMOS)\r\nKaroliina Lehtinen: ANR QUASY 23-CE48-0008-01\r\nAditya
  Prakash: Chancellors’ International Scholarship from the University of Warwick and
  Centre for Discrete Mathematics and Its Applications (DIMAP)"
alternative_title:
- LIPIcs
article_number: '12'
article_processing_charge: No
arxiv: 1
author:
- first_name: Udi
  full_name: Boker, Udi
  id: 31E297B6-F248-11E8-B48F-1D18A9856A87
  last_name: Boker
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Karoliina
  full_name: Lehtinen, Karoliina
  last_name: Lehtinen
- first_name: Aditya
  full_name: Prakash, Aditya
  last_name: Prakash
citation:
  ama: 'Boker U, Henzinger TA, Lehtinen K, Prakash A. History-determinism vs fair
    simulation. In: <i>35th International Conference on Concurrency Theory</i>. Vol
    311. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.12">10.4230/LIPIcs.CONCUR.2024.12</a>'
  apa: 'Boker, U., Henzinger, T. A., Lehtinen, K., &#38; Prakash, A. (2024). History-determinism
    vs fair simulation. In <i>35th International Conference on Concurrency Theory</i>
    (Vol. 311). Calgary, Canada: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
    <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.12">https://doi.org/10.4230/LIPIcs.CONCUR.2024.12</a>'
  chicago: Boker, Udi, Thomas A Henzinger, Karoliina Lehtinen, and Aditya Prakash.
    “History-Determinism vs Fair Simulation.” In <i>35th International Conference
    on Concurrency Theory</i>, Vol. 311. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2024. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.12">https://doi.org/10.4230/LIPIcs.CONCUR.2024.12</a>.
  ieee: U. Boker, T. A. Henzinger, K. Lehtinen, and A. Prakash, “History-determinism
    vs fair simulation,” in <i>35th International Conference on Concurrency Theory</i>,
    Calgary, Canada, 2024, vol. 311.
  ista: 'Boker U, Henzinger TA, Lehtinen K, Prakash A. 2024. History-determinism vs
    fair simulation. 35th International Conference on Concurrency Theory. CONCUR:
    Conference on Concurrency Theory, LIPIcs, vol. 311, 12.'
  mla: Boker, Udi, et al. “History-Determinism vs Fair Simulation.” <i>35th International
    Conference on Concurrency Theory</i>, vol. 311, 12, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2024, doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.12">10.4230/LIPIcs.CONCUR.2024.12</a>.
  short: U. Boker, T.A. Henzinger, K. Lehtinen, A. Prakash, in:, 35th International
    Conference on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2024.
conference:
  end_date: 2024-09-13
  location: Calgary, Canada
  name: 'CONCUR: Conference on Concurrency Theory'
  start_date: 2024-09-09
corr_author: '1'
date_created: 2024-09-15T22:01:40Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-12-02T13:44:54Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.CONCUR.2024.12
ec_funded: 1
external_id:
  arxiv:
  - '2407.08620'
  isi:
  - '001556847400012'
file:
- access_level: open_access
  checksum: 66db11ef8e600a434079c278050c3f09
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-17T07:31:18Z
  date_updated: 2024-09-17T07:31:18Z
  file_id: '18080'
  file_name: 2024_LIPICS_Boker.pdf
  file_size: 766902
  relation: main_file
  success: 1
file_date_updated: 2024-09-17T07:31:18Z
has_accepted_license: '1'
intvolume: '       311'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 35th International Conference on Concurrency Theory
publication_identifier:
  isbn:
  - '9783959773393'
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: History-determinism vs fair simulation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 311
year: '2024'
...
---
OA_place: publisher
OA_type: gold
_id: '18068'
abstract:
- lang: eng
  text: "We study the following refinement relation between nondeterministic state-transition
    models: model ℬ strategically dominates model \U0001D49C iff every deterministic
    refinement of \U0001D49C is language contained in some deterministic refinement
    of ℬ. While language containment is trace inclusion, and the (fair) simulation
    preorder coincides with tree inclusion, strategic dominance falls strictly between
    the two and can be characterized as \"strategy inclusion\" between \U0001D49C
    and ℬ: every strategy that resolves the nondeterminism of \U0001D49C is dominated
    by a strategy that resolves the nondeterminism of ℬ. Strategic dominance can be
    checked in 2-ExpTime by a decidable first-order Presburger logic with quantification
    over words and strategies, called resolver logic. We give several other applications
    of resolver logic, including checking the co-safety, co-liveness, and history-determinism
    of boolean and quantitative automata, and checking the inclusion between hyperproperties
    that are specified by nondeterministic boolean and quantitative automata."
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. N.
  Mazzocchi was affiliated with ISTA when this work was submitted for publication.
alternative_title:
- LIPIcs
article_number: '29'
article_processing_charge: Yes
arxiv: 1
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Nicolas Adrien
  full_name: Mazzocchi, Nicolas Adrien
  id: b26baa86-3308-11ec-87b0-8990f34baa85
  last_name: Mazzocchi
- first_name: Naci E
  full_name: Sarac, Naci E
  id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425
  last_name: Sarac
citation:
  ama: 'Henzinger TA, Mazzocchi NA, Sarac NE. Strategic dominance: A new preorder
    for nondeterministic processes. In: <i>35th International Conference on Concurrency
    Theory</i>. Vol 311. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024.
    doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.29">10.4230/LIPIcs.CONCUR.2024.29</a>'
  apa: 'Henzinger, T. A., Mazzocchi, N. A., &#38; Sarac, N. E. (2024). Strategic dominance:
    A new preorder for nondeterministic processes. In <i>35th International Conference
    on Concurrency Theory</i> (Vol. 311). Calgary, Canada: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.29">https://doi.org/10.4230/LIPIcs.CONCUR.2024.29</a>'
  chicago: 'Henzinger, Thomas A, Nicolas Adrien Mazzocchi, and Naci E Sarac. “Strategic
    Dominance: A New Preorder for Nondeterministic Processes.” In <i>35th International
    Conference on Concurrency Theory</i>, Vol. 311. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2024. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.29">https://doi.org/10.4230/LIPIcs.CONCUR.2024.29</a>.'
  ieee: 'T. A. Henzinger, N. A. Mazzocchi, and N. E. Sarac, “Strategic dominance:
    A new preorder for nondeterministic processes,” in <i>35th International Conference
    on Concurrency Theory</i>, Calgary, Canada, 2024, vol. 311.'
  ista: 'Henzinger TA, Mazzocchi NA, Sarac NE. 2024. Strategic dominance: A new preorder
    for nondeterministic processes. 35th International Conference on Concurrency Theory.
    CONCUR: Conference on Concurrency Theory, LIPIcs, vol. 311, 29.'
  mla: 'Henzinger, Thomas A., et al. “Strategic Dominance: A New Preorder for Nondeterministic
    Processes.” <i>35th International Conference on Concurrency Theory</i>, vol. 311,
    29, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2024.29">10.4230/LIPIcs.CONCUR.2024.29</a>.'
  short: T.A. Henzinger, N.A. Mazzocchi, N.E. Sarac, in:, 35th International Conference
    on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024.
conference:
  end_date: 2024-09-13
  location: Calgary, Canada
  name: 'CONCUR: Conference on Concurrency Theory'
  start_date: 2024-09-09
corr_author: '1'
date_created: 2024-09-15T22:01:40Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-12-02T13:45:38Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
- _id: GradSch
doi: 10.4230/LIPIcs.CONCUR.2024.29
ec_funded: 1
external_id:
  arxiv:
  - '2407.10473'
  isi:
  - '001556847400029'
file:
- access_level: open_access
  checksum: 555bd343e1fb38adeab8fc465ff4fad8
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-17T07:48:56Z
  date_updated: 2024-09-17T07:48:56Z
  file_id: '18081'
  file_name: 2024_LIPICS_Henzinger.pdf
  file_size: 964124
  relation: main_file
  success: 1
file_date_updated: 2024-09-17T07:48:56Z
has_accepted_license: '1'
intvolume: '       311'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 35th International Conference on Concurrency Theory
publication_identifier:
  isbn:
  - '9783959773393'
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Strategic dominance: A new preorder for nondeterministic processes'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 311
year: '2024'
...
---
DOAJ_listed: '1'
_id: '18069'
abstract:
- lang: eng
  text: We present results from the JWST First Reionization Epoch Spectroscopically
    Complete Observations survey on the star-forming sequence (SFS) of galaxies at
    1.0 < z < 1.7, around the peak of the cosmic star formation history. Star formation
    rates (SFRs) are measured from the redshifted, relatively dust-insensitive Paschen-α
    emission line, and stellar mass measurements include the F444W (4.4 μm; rest-frame
    H) band. We find SFRs of galaxies with log(M*/M⊙) > 9.5 that are lower than found
    in many earlier studies by up to 0.6 dex, but in good agreement with recent results
    obtained with the Prospector fitting framework. The difference (log(SFR(Paα)-SFR(Prospector))
    is −0.09 ± 0.04 dex at 1010−11M⊙. We also measure the empirical relation between
    Paschen-α luminosity and rest-frame H-band magnitude and find that the scatter
    is only 0.04 dex lower than that of the SFR–M* relation and is much lower than
    the systematic differences among relations in the literature due to various methods
    of converting observed measurements to physical properties. We additionally identify
    examples of sources—that, with standard cutoffs via the UVJ diagram, would be
    deemed quiescent—with significant (log(sSFR)> −11 yr−1), typically extended, Paschen-α
    emission. Our results may be indicative of the potential unification of methods
    used to derive the SFS with careful selection of star-forming galaxies and independent
    SFR and stellar mass indicators.
acknowledgement: "The authors thank the anonymous referee whose comments and suggestions
  improved the quality of this work.\r\nThis work is based on observations made with
  the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski
  Archive for Space Telescopes at the Space Telescope Science Institute, which is
  operated by the Association of Universities for Research in Astronomy, Inc., under
  NASA contract NAS 5-03127 for JWST. These observations are associated with program
  No. 1895.\r\nSupport for this work was provided by NASA through grant JWST-GO-01895
  awarded by the Space Telescope Science Institute, which is operated by the Association
  of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.\r\nThis
  work has received funding from the Swiss State Secretariat for Education, Research,
  and Innovation (SERI) under contract No. MB22.00072, as well as from the Swiss National
  Science Foundation (SNSF) through project grant 200020_207349. The Cosmic Dawn Center
  (DAWN) is funded by the Danish National Research Foundation under grant No. 140.\r\nR.P.N.
  acknowledges funding from JWST programs GO-1933 and GO-2279. Support for this work
  was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A
  awarded by the Space Telescope Science Institute, which is operated by the Association
  of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555\r\nCloud-based
  data processing and file storage for this work is provided by the AWS Cloud Credits
  for Research program.\r\nThis paper made use of several publicly available software
  packages. We thank the respective authors for sharing their work: IPython (Pérez
  & Granger 2007), matplotlib (Hunter 2007), seaborn (Waskom et al. 2018), NumPy (Harris
  et al. 2020), SciPy (Virtanen et al. 2020), jupyter (Kluyver et al. 2016), Astropy
  (Astropy Collaboration et al. 2013, 2018, 2022), grizli (Brammer 2018; Brammer et
  al. 2022), Prospector (Leja et al. 2019, 2017; Johnson et al. 2021), FSPS (Conroy
  et al. 2009a, 2010; Conroy & Gunn 2010a, 2010b; Foreman-Mackey et al. 2014), dynesty
  (Speagle 2020), EAZY (Brammer et al. 2008), Bagpipes (Carnall et al. 2018), and
  SExtractor (Bertin & Arnouts 1996)."
article_number: '156'
article_processing_charge: Yes
article_type: original
author:
- first_name: Chloe
  full_name: Neufeld, Chloe
  last_name: Neufeld
- first_name: Pieter
  full_name: Van Dokkum, Pieter
  last_name: Van Dokkum
- first_name: Yasmeen
  full_name: Asali, Yasmeen
  last_name: Asali
- first_name: Alba
  full_name: Covelo-Paz, Alba
  last_name: Covelo-Paz
- first_name: Joel
  full_name: Leja, Joel
  last_name: Leja
- first_name: Jamie
  full_name: Lin, Jamie
  last_name: Lin
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Pascal A.
  full_name: Oesch, Pascal A.
  last_name: Oesch
- first_name: Naveen A.
  full_name: Reddy, Naveen A.
  last_name: Reddy
- first_name: Irene
  full_name: Shivaei, Irene
  last_name: Shivaei
- first_name: Katherine E.
  full_name: Whitaker, Katherine E.
  last_name: Whitaker
- first_name: Stijn
  full_name: Wuyts, Stijn
  last_name: Wuyts
- first_name: Gabriel
  full_name: Brammer, Gabriel
  last_name: Brammer
- first_name: Danilo
  full_name: Marchesini, Danilo
  last_name: Marchesini
- first_name: Michael V.
  full_name: Maseda, Michael V.
  last_name: Maseda
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Erica J.
  full_name: Nelson, Erica J.
  last_name: Nelson
- first_name: Anna
  full_name: Velichko, Anna
  last_name: Velichko
- first_name: Andrea
  full_name: Weibel, Andrea
  last_name: Weibel
- first_name: Mengyuan
  full_name: Xiao, Mengyuan
  last_name: Xiao
citation:
  ama: 'Neufeld C, Van Dokkum P, Asali Y, et al. FRESCO: The Paschen-α star-forming
    sequence at cosmic noon. <i>Astrophysical Journal</i>. 2024;972(2). doi:<a href="https://doi.org/10.3847/1538-4357/ad6158">10.3847/1538-4357/ad6158</a>'
  apa: 'Neufeld, C., Van Dokkum, P., Asali, Y., Covelo-Paz, A., Leja, J., Lin, J.,
    … Xiao, M. (2024). FRESCO: The Paschen-α star-forming sequence at cosmic noon.
    <i>Astrophysical Journal</i>. IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/ad6158">https://doi.org/10.3847/1538-4357/ad6158</a>'
  chicago: 'Neufeld, Chloe, Pieter Van Dokkum, Yasmeen Asali, Alba Covelo-Paz, Joel
    Leja, Jamie Lin, Jorryt J Matthee, et al. “FRESCO: The Paschen-α Star-Forming
    Sequence at Cosmic Noon.” <i>Astrophysical Journal</i>. IOP Publishing, 2024.
    <a href="https://doi.org/10.3847/1538-4357/ad6158">https://doi.org/10.3847/1538-4357/ad6158</a>.'
  ieee: 'C. Neufeld <i>et al.</i>, “FRESCO: The Paschen-α star-forming sequence at
    cosmic noon,” <i>Astrophysical Journal</i>, vol. 972, no. 2. IOP Publishing, 2024.'
  ista: 'Neufeld C, Van Dokkum P, Asali Y, Covelo-Paz A, Leja J, Lin J, Matthee JJ,
    Oesch PA, Reddy NA, Shivaei I, Whitaker KE, Wuyts S, Brammer G, Marchesini D,
    Maseda MV, Naidu RP, Nelson EJ, Velichko A, Weibel A, Xiao M. 2024. FRESCO: The
    Paschen-α star-forming sequence at cosmic noon. Astrophysical Journal. 972(2),
    156.'
  mla: 'Neufeld, Chloe, et al. “FRESCO: The Paschen-α Star-Forming Sequence at Cosmic
    Noon.” <i>Astrophysical Journal</i>, vol. 972, no. 2, 156, IOP Publishing, 2024,
    doi:<a href="https://doi.org/10.3847/1538-4357/ad6158">10.3847/1538-4357/ad6158</a>.'
  short: C. Neufeld, P. Van Dokkum, Y. Asali, A. Covelo-Paz, J. Leja, J. Lin, J.J.
    Matthee, P.A. Oesch, N.A. Reddy, I. Shivaei, K.E. Whitaker, S. Wuyts, G. Brammer,
    D. Marchesini, M.V. Maseda, R.P. Naidu, E.J. Nelson, A. Velichko, A. Weibel, M.
    Xiao, Astrophysical Journal 972 (2024).
date_created: 2024-09-15T22:01:40Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-09-08T09:43:41Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/ad6158
external_id:
  isi:
  - '001305987600001'
file:
- access_level: open_access
  checksum: 754b58c1d79adb9670ca76fa8c20ab16
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-17T08:23:59Z
  date_updated: 2024-09-17T08:23:59Z
  file_id: '18082'
  file_name: 2024_AstrophysicalJourn_Neufeld.pdf
  file_size: 9960685
  relation: main_file
  success: 1
file_date_updated: 2024-09-17T08:23:59Z
has_accepted_license: '1'
intvolume: '       972'
isi: 1
issue: '2'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'FRESCO: The Paschen-α star-forming sequence at cosmic noon'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 972
year: '2024'
...
---
_id: '18070'
abstract:
- lang: eng
  text: Parallel SGD in a shared-memory setting is oft-represented by the popular
    Hogwild! algorithm, in which lock-free updates are asynchronously performed by
    multiple computing processes. Unfortunately, scaling Hogwild! to distributed workers
    is largely unexplored. Specifically, it is unknown if any adaptation of Hogwild!
    to the popular decentralized multi-GPU setting offers any competitive speedup,
    either empirically or theoretically. In this work, we investigate the potential
    of decentralizing Hogwild! by incorporating simultaneously (a) asynchronous local
    gradient updates on the shared memory of GPUs, and (b) non-blocking asynchronous
    decentralized federated averaging. A naive direct implementation shows degradation
    in performance, arising from scheduling overheads and concurrent write conflicts
    on GPUs. To mitigate these drawbacks, we investigate and propose a new method,
    based on careful block selection rules, which update only portions of the parameter
    vectors. Our experiments show that the resulting decentralized training method
    exhibits improved throughput and competitive accuracy for standard image classification
    benchmarks on the CIFAR-10, CIFAR-100, and Imagenet datasets. On the theoretical
    side, we prove that our method guarantees sublinear ergodic convergence rates
    for non-convex objectives.
article_processing_charge: No
author:
- first_name: Bapi
  full_name: Chatterjee, Bapi
  id: 3C41A08A-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-2742-4028
- first_name: Vyacheslav
  full_name: Kungurtsev, Vyacheslav
  last_name: Kungurtsev
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Chatterjee B, Kungurtsev V, Alistarh D-A. Federated SGD with local asynchrony.
    In: <i>Proceedings of the 44th International Conference on Distributed Computing
    Systems</i>. IEEE; 2024:857-868. doi:<a href="https://doi.org/10.1109/ICDCS60910.2024.00084">10.1109/ICDCS60910.2024.00084</a>'
  apa: 'Chatterjee, B., Kungurtsev, V., &#38; Alistarh, D.-A. (2024). Federated SGD
    with local asynchrony. In <i>Proceedings of the 44th International Conference
    on Distributed Computing Systems</i> (pp. 857–868). Jersey City, NJ, United States:
    IEEE. <a href="https://doi.org/10.1109/ICDCS60910.2024.00084">https://doi.org/10.1109/ICDCS60910.2024.00084</a>'
  chicago: Chatterjee, Bapi, Vyacheslav Kungurtsev, and Dan-Adrian Alistarh. “Federated
    SGD with Local Asynchrony.” In <i>Proceedings of the 44th International Conference
    on Distributed Computing Systems</i>, 857–68. IEEE, 2024. <a href="https://doi.org/10.1109/ICDCS60910.2024.00084">https://doi.org/10.1109/ICDCS60910.2024.00084</a>.
  ieee: B. Chatterjee, V. Kungurtsev, and D.-A. Alistarh, “Federated SGD with local
    asynchrony,” in <i>Proceedings of the 44th International Conference on Distributed
    Computing Systems</i>, Jersey City, NJ, United States, 2024, pp. 857–868.
  ista: 'Chatterjee B, Kungurtsev V, Alistarh D-A. 2024. Federated SGD with local
    asynchrony. Proceedings of the 44th International Conference on Distributed Computing
    Systems. ICDCS: International Conference on Distributed Computing Systems, 857–868.'
  mla: Chatterjee, Bapi, et al. “Federated SGD with Local Asynchrony.” <i>Proceedings
    of the 44th International Conference on Distributed Computing Systems</i>, IEEE,
    2024, pp. 857–68, doi:<a href="https://doi.org/10.1109/ICDCS60910.2024.00084">10.1109/ICDCS60910.2024.00084</a>.
  short: B. Chatterjee, V. Kungurtsev, D.-A. Alistarh, in:, Proceedings of the 44th
    International Conference on Distributed Computing Systems, IEEE, 2024, pp. 857–868.
conference:
  end_date: 2024-07-26
  location: Jersey City, NJ, United States
  name: 'ICDCS: International Conference on Distributed Computing Systems'
  start_date: 2024-07-23
corr_author: '1'
date_created: 2024-09-15T22:01:41Z
date_published: 2024-07-26T00:00:00Z
date_updated: 2025-09-08T09:23:48Z
day: '26'
department:
- _id: DaAl
doi: 10.1109/ICDCS60910.2024.00084
external_id:
  isi:
  - '001304430200075'
isi: 1
language:
- iso: eng
month: '07'
oa_version: None
page: 857-868
publication: Proceedings of the 44th International Conference on Distributed Computing
  Systems
publication_identifier:
  eissn:
  - 2575-8411
  isbn:
  - '9798350386059'
  issn:
  - 1063-6927
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Federated SGD with local asynchrony
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '18071'
abstract:
- lang: eng
  text: Recent advancements on DAG-based consensus protocols allow for blockchains
    with improved metrics and properties, such as throughput and censorship-resistance.
    Variants of the Bullshark [18] consensus protocol are adopted for practical use
    by the Sui blockchain, for improved latency. However, the protocol is leader-based,
    and is strongly affected by crashed leaders that can lead to various performance
    issues, for example, decreased transaction throughput. In this paper, we propose
    HammerHead, a DAG-based consensus protocol, that is inspired by Carousel [8] and
    provides Leader-Utilization. Our proposal differs from Carousel, which is built
    for a chained consensus protocol; in HammerHead chain quality is inherited by
    the DAG. HammerHead needs to preserve safety and liveness, despite validators
    committing leader vertices asynchronously. The key idea is to update leader schedules
    dynamically, based on the validators' scores during the previous schedule. We
    implement HammerHead and show a minor improvement in performance for cases without
    faults. The major improvements in comparison to Bullshark appear in faulty settings.
    Specifically, we show a drastic, 2x-latency improvement and up to 40% increased
    throughput when crash faults occur (100 validators, 33 faults).
acknowledgement: This work is supported by Mysten Labs. We thank the Mysten Labs Engineering
  teams for valuable feedback broadly, and specifically to Laura Makdah for helping
  implementing the early reputation score system for validators and Dmitry Perelman
  for managing the overall implementation effort.
article_processing_charge: No
arxiv: 1
author:
- first_name: Giorgos
  full_name: Tsimos, Giorgos
  last_name: Tsimos
- first_name: Anastasios
  full_name: Kichidis, Anastasios
  last_name: Kichidis
- first_name: Alberto
  full_name: Sonnino, Alberto
  last_name: Sonnino
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
citation:
  ama: 'Tsimos G, Kichidis A, Sonnino A, Kokoris Kogias E. HammerHead: Leader reputation
    for dynamic scheduling. In: <i>Proceedings - International Conference on Distributed
    Computing Systems</i>. IEEE; 2024:1377-1387. doi:<a href="https://doi.org/10.1109/ICDCS60910.2024.00129">10.1109/ICDCS60910.2024.00129</a>'
  apa: 'Tsimos, G., Kichidis, A., Sonnino, A., &#38; Kokoris Kogias, E. (2024). HammerHead:
    Leader reputation for dynamic scheduling. In <i>Proceedings - International Conference
    on Distributed Computing Systems</i> (pp. 1377–1387). Jersey City, NJ, United
    States: IEEE. <a href="https://doi.org/10.1109/ICDCS60910.2024.00129">https://doi.org/10.1109/ICDCS60910.2024.00129</a>'
  chicago: 'Tsimos, Giorgos, Anastasios Kichidis, Alberto Sonnino, and Eleftherios
    Kokoris Kogias. “HammerHead: Leader Reputation for Dynamic Scheduling.” In <i>Proceedings
    - International Conference on Distributed Computing Systems</i>, 1377–87. IEEE,
    2024. <a href="https://doi.org/10.1109/ICDCS60910.2024.00129">https://doi.org/10.1109/ICDCS60910.2024.00129</a>.'
  ieee: 'G. Tsimos, A. Kichidis, A. Sonnino, and E. Kokoris Kogias, “HammerHead: Leader
    reputation for dynamic scheduling,” in <i>Proceedings - International Conference
    on Distributed Computing Systems</i>, Jersey City, NJ, United States, 2024, pp.
    1377–1387.'
  ista: 'Tsimos G, Kichidis A, Sonnino A, Kokoris Kogias E. 2024. HammerHead: Leader
    reputation for dynamic scheduling. Proceedings - International Conference on Distributed
    Computing Systems. ICDCS: International Conference on Distributed Computing Systems,
    1377–1387.'
  mla: 'Tsimos, Giorgos, et al. “HammerHead: Leader Reputation for Dynamic Scheduling.”
    <i>Proceedings - International Conference on Distributed Computing Systems</i>,
    IEEE, 2024, pp. 1377–87, doi:<a href="https://doi.org/10.1109/ICDCS60910.2024.00129">10.1109/ICDCS60910.2024.00129</a>.'
  short: G. Tsimos, A. Kichidis, A. Sonnino, E. Kokoris Kogias, in:, Proceedings -
    International Conference on Distributed Computing Systems, IEEE, 2024, pp. 1377–1387.
conference:
  end_date: 2024-07-26
  location: Jersey City, NJ, United States
  name: 'ICDCS: International Conference on Distributed Computing Systems'
  start_date: 2024-07-23
date_created: 2024-09-15T22:01:41Z
date_published: 2024-07-26T00:00:00Z
date_updated: 2025-09-08T09:42:36Z
day: '26'
department:
- _id: ElKo
doi: 10.1109/ICDCS60910.2024.00129
external_id:
  arxiv:
  - '2309.12713'
  isi:
  - '001304430200120'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2309.12713
month: '07'
oa: 1
oa_version: Preprint
page: 1377-1387
publication: Proceedings - International Conference on Distributed Computing Systems
publication_identifier:
  eissn:
  - 2575-8411
  isbn:
  - '9798350386059'
  issn:
  - 1063-6927
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'HammerHead: Leader reputation for dynamic scheduling'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '18072'
abstract:
- lang: eng
  text: The individualization of chromosomes during early mitosis and their clustering
    upon exit from cell division are two key transitions that ensure efficient segregation
    of eukaryotic chromosomes. Both processes are regulated by the surfactant-like
    protein Ki-67, but how Ki-67 achieves these diametric functions has remained unknown.
    Here, we report that Ki-67 radically switches from a chromosome repellent to a
    chromosome attractant during anaphase in human cells. We show that Ki-67 dephosphorylation
    during mitotic exit and the simultaneous exposure of a conserved basic patch induce
    the RNA-dependent formation of a liquid-like condensed phase on the chromosome
    surface. Experiments and coarse-grained simulations support a model in which the
    coalescence of chromosome surfaces, driven by co-condensation of Ki-67 and RNA,
    promotes clustering of chromosomes. Our study reveals how the switch of Ki-67
    from a surfactant to a liquid-like condensed phase can generate mechanical forces
    during genome segregation that are required for re-establishing nuclear-cytoplasmic
    compartmentalization after mitosis.
acknowledgement: We thank Daniel W. Gerlich for providing cell lines, the EMBL Advanced
  Light Microscopy Facility (ALMF) for support, Christian H. Haering and Thomas Quail
  for input on the manuscript, and Martina Dees for cloning several Ki-67 constructs.
  This work was supported by the German Research Foundation (DFG project number 402723784)
  and the Human Frontier Science Program (CDA00045/2019). A.H.-A. and A.B. have received
  PhD fellowships from the Boehringer Ingelheim Fonds, V.S. and A.Š. were supported
  by the European Research Council (ERC) under the European Union’s Horizon 2020 research
  and innovation programme (grant no. 802960), and Y.H. was supported by a fellowship
  from the EMBL interdisciplinary Postdoc (EIPOD) program (Marie Sklodowska-Curie
  Actions, COFUND grant agreement 664726).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Alberto
  full_name: Hernandez-Armendariz, Alberto
  last_name: Hernandez-Armendariz
- first_name: Valerio
  full_name: Sorichetti, Valerio
  id: ef8a92cb-c7b6-11ec-8bea-e1fd5847bc5b
  last_name: Sorichetti
  orcid: 0000-0002-9645-6576
- first_name: Yuki
  full_name: Hayashi, Yuki
  last_name: Hayashi
- first_name: Zuzana
  full_name: Koskova, Zuzana
  last_name: Koskova
- first_name: Andreas
  full_name: Brunner, Andreas
  last_name: Brunner
- first_name: Jan
  full_name: Ellenberg, Jan
  last_name: Ellenberg
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Sara
  full_name: Cuylen-Haering, Sara
  last_name: Cuylen-Haering
citation:
  ama: Hernandez-Armendariz A, Sorichetti V, Hayashi Y, et al. A liquid-like coat
    mediates chromosome clustering during mitotic exit. <i>Molecular Cell</i>. 2024;84(17):P3254-3270.E9.
    doi:<a href="https://doi.org/10.1016/j.molcel.2024.07.022">10.1016/j.molcel.2024.07.022</a>
  apa: Hernandez-Armendariz, A., Sorichetti, V., Hayashi, Y., Koskova, Z., Brunner,
    A., Ellenberg, J., … Cuylen-Haering, S. (2024). A liquid-like coat mediates chromosome
    clustering during mitotic exit. <i>Molecular Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.molcel.2024.07.022">https://doi.org/10.1016/j.molcel.2024.07.022</a>
  chicago: Hernandez-Armendariz, Alberto, Valerio Sorichetti, Yuki Hayashi, Zuzana
    Koskova, Andreas Brunner, Jan Ellenberg, Anđela Šarić, and Sara Cuylen-Haering.
    “A Liquid-like Coat Mediates Chromosome Clustering during Mitotic Exit.” <i>Molecular
    Cell</i>. Cell Press, 2024. <a href="https://doi.org/10.1016/j.molcel.2024.07.022">https://doi.org/10.1016/j.molcel.2024.07.022</a>.
  ieee: A. Hernandez-Armendariz <i>et al.</i>, “A liquid-like coat mediates chromosome
    clustering during mitotic exit,” <i>Molecular Cell</i>, vol. 84, no. 17. Cell
    Press, p. P3254–3270.E9, 2024.
  ista: Hernandez-Armendariz A, Sorichetti V, Hayashi Y, Koskova Z, Brunner A, Ellenberg
    J, Šarić A, Cuylen-Haering S. 2024. A liquid-like coat mediates chromosome clustering
    during mitotic exit. Molecular Cell. 84(17), P3254–3270.E9.
  mla: Hernandez-Armendariz, Alberto, et al. “A Liquid-like Coat Mediates Chromosome
    Clustering during Mitotic Exit.” <i>Molecular Cell</i>, vol. 84, no. 17, Cell
    Press, 2024, p. P3254–3270.E9, doi:<a href="https://doi.org/10.1016/j.molcel.2024.07.022">10.1016/j.molcel.2024.07.022</a>.
  short: A. Hernandez-Armendariz, V. Sorichetti, Y. Hayashi, Z. Koskova, A. Brunner,
    J. Ellenberg, A. Šarić, S. Cuylen-Haering, Molecular Cell 84 (2024) P3254–3270.E9.
date_created: 2024-09-15T22:01:41Z
date_published: 2024-09-05T00:00:00Z
date_updated: 2025-09-08T09:23:02Z
day: '05'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1016/j.molcel.2024.07.022
ec_funded: 1
external_id:
  isi:
  - '001309051100001'
  pmid:
  - '39153474'
file:
- access_level: open_access
  checksum: 3f360e0287b8ec79fb2b8b02b5070360
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-16T07:38:38Z
  date_updated: 2024-09-16T07:38:38Z
  file_id: '18075'
  file_name: 2024_MolecularCell_HernandezArmendariz.pdf
  file_size: 11654644
  relation: main_file
  success: 1
file_date_updated: 2024-09-16T07:38:38Z
has_accepted_license: '1'
intvolume: '        84'
isi: 1
issue: '17'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: P3254-3270.E9
pmid: 1
project:
- _id: eba2549b-77a9-11ec-83b8-a81e493eae4e
  call_identifier: H2020
  grant_number: '802960'
  name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines'
publication: Molecular Cell
publication_identifier:
  eissn:
  - 1097-4164
  issn:
  - 1097-2765
publication_status: published
publisher: Cell Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A liquid-like coat mediates chromosome clustering during mitotic exit
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 84
year: '2024'
...
---
OA_place: publisher
OA_type: gold
_id: '18073'
abstract:
- lang: eng
  text: Conserved signaling cascades monitor protein-folding homeostasis to ensure
    proper cellular function. One of the evolutionary conserved key players is IRE1,
    which maintains endoplasmic reticulum (ER) homeostasis through the unfolded protein
    response (UPR). Upon accumulation of misfolded proteins in the ER, IRE1 forms
    clusters on the ER membrane to initiate UPR signaling. What regulates IRE1 cluster
    formation is not fully understood. Here, we show that the ER lumenal domain (LD)
    of human IRE1α forms biomolecular condensates in vitro. IRE1α LD condensates were
    stabilized both by binding to unfolded polypeptides as well as by tethering to
    model membranes, suggesting their role in assembling IRE1α into signaling-competent
    stable clusters. Molecular dynamics simulations indicated that weak multivalent
    interactions drive IRE1α LD clustering. Mutagenesis experiments identified disordered
    regions in IRE1α LD to control its clustering in vitro and in cells. Importantly,
    dysregulated clustering of IRE1α mutants led to defects in IRE1α signaling. Our
    results revealed that disordered regions in IRE1α LD control its clustering and
    suggest their role as a common strategy in regulating protein assembly on membranes.
acknowledgement: We thank late Thomas Peterbauer at the Max Perutz Labs Biooptics
  Light Microscopy Facility for his help and support. We are grateful to Kitti Csalyi
  and Thomas Sauer at Max Perutz Labs Biooptics FACS facility for their help. We thank
  Grzegorz Scibisz and Sertan Atilla for their support with the expression and purification
  of mCherry-IRE1α LD-10His. We are grateful to Aleksandra S Anisimova with her help
  in the generation of stable cell lines and the statistical analyses of the data.
  We thank Venja Vieweger for her help with the characterization of the WLLI and D123P
  IRE1 mutants in cells. We are thankful to Monika Kubickova for the help with the
  AUC experiments. We acknowledge CF BIC of CIISB, Instruct-CZ Centre, supported by
  MEYS CR (LM2023042)) and European Regional Development Fund-Project, UP CIISB“ (No.
  CZ.02.1.01/0.0/0.0/18_046/0015974). We thank the members of the Karagöz lab for
  the critical reading and editing of the manuscript. We are thankful to our colleagues
  Diego Acosta-Alvear, Vladislav Belyy, Jirka Peschek, Yasin Dagdas, Javier Martinez,
  Sascha Martens and Alwin Köhler for their invaluable input on the manuscript. We
  are grateful to Life Science Editors, especially Katrina Woolcock for her useful
  edits and comments on the manuscript. We acknowledge funding from Austrian Science
  Fund (FWF-SFB F79 and FWF-W 1261) to GEK. PK acknowledges the support of the Max
  Perutz PhD fellowship. GAV is funded by Stand-Alone grants (P30231-B, P30415-B,
  P36572), Special Research Grant (SFB grant F79), and Doctoral School grant (DK grant
  W1261) from the Austrian Science Fund (FWF). ES and RC acknowledge support and funding
  by the Frankfurt Institute of Advanced Studies, the LOEWE Center for Multiscale
  Modelling in Life Sciences of the state of Hesse, the Collaborative Research Center
  1507 “Membrane-associated Protein Assemblies, Machineries, and Supercomplexes” (Project
  ID 450648163), and the International Max Planck Research School on Cellular Biophysics
  (to RC), the Center for Scientific Computing of the Goethe University and the Jülich
  Supercomputing Centre for computational resources and support.
article_processing_charge: Yes
article_type: original
author:
- first_name: Paulina
  full_name: Kettel, Paulina
  last_name: Kettel
- first_name: Laura
  full_name: Marosits, Laura
  last_name: Marosits
- first_name: Elena
  full_name: Spinetti, Elena
  last_name: Spinetti
- first_name: Michael
  full_name: Rechberger, Michael
  last_name: Rechberger
- first_name: Caterina
  full_name: Giannini, Caterina
  id: e3fdddd5-f6e0-11ea-865d-ca99ee6367f4
  last_name: Giannini
- first_name: Philipp
  full_name: Radler, Philipp
  id: 40136C2A-F248-11E8-B48F-1D18A9856A87
  last_name: Radler
  orcid: '0000-0001-9198-2182 '
- first_name: Isabell
  full_name: Niedermoser, Isabell
  last_name: Niedermoser
- first_name: Irmgard
  full_name: Fischer, Irmgard
  last_name: Fischer
- first_name: Gijs A.
  full_name: Versteeg, Gijs A.
  last_name: Versteeg
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Roberto
  full_name: Covino, Roberto
  last_name: Covino
- first_name: G. Elif
  full_name: Karagöz, G. Elif
  last_name: Karagöz
citation:
  ama: Kettel P, Marosits L, Spinetti E, et al. Disordered regions in the IRE1α ER
    lumenal domain mediate its stress-induced clustering. <i>EMBO Journal</i>. 2024;43(20):4668-4698.
    doi:<a href="https://doi.org/10.1038/s44318-024-00207-0">10.1038/s44318-024-00207-0</a>
  apa: Kettel, P., Marosits, L., Spinetti, E., Rechberger, M., Giannini, C., Radler,
    P., … Karagöz, G. E. (2024). Disordered regions in the IRE1α ER lumenal domain
    mediate its stress-induced clustering. <i>EMBO Journal</i>. Embo Press. <a href="https://doi.org/10.1038/s44318-024-00207-0">https://doi.org/10.1038/s44318-024-00207-0</a>
  chicago: Kettel, Paulina, Laura Marosits, Elena Spinetti, Michael Rechberger, Caterina
    Giannini, Philipp Radler, Isabell Niedermoser, et al. “Disordered Regions in the
    IRE1α ER Lumenal Domain Mediate Its Stress-Induced Clustering.” <i>EMBO Journal</i>.
    Embo Press, 2024. <a href="https://doi.org/10.1038/s44318-024-00207-0">https://doi.org/10.1038/s44318-024-00207-0</a>.
  ieee: P. Kettel <i>et al.</i>, “Disordered regions in the IRE1α ER lumenal domain
    mediate its stress-induced clustering,” <i>EMBO Journal</i>, vol. 43, no. 20.
    Embo Press, pp. 4668–4698, 2024.
  ista: Kettel P, Marosits L, Spinetti E, Rechberger M, Giannini C, Radler P, Niedermoser
    I, Fischer I, Versteeg GA, Loose M, Covino R, Karagöz GE. 2024. Disordered regions
    in the IRE1α ER lumenal domain mediate its stress-induced clustering. EMBO Journal.
    43(20), 4668–4698.
  mla: Kettel, Paulina, et al. “Disordered Regions in the IRE1α ER Lumenal Domain
    Mediate Its Stress-Induced Clustering.” <i>EMBO Journal</i>, vol. 43, no. 20,
    Embo Press, 2024, pp. 4668–98, doi:<a href="https://doi.org/10.1038/s44318-024-00207-0">10.1038/s44318-024-00207-0</a>.
  short: P. Kettel, L. Marosits, E. Spinetti, M. Rechberger, C. Giannini, P. Radler,
    I. Niedermoser, I. Fischer, G.A. Versteeg, M. Loose, R. Covino, G.E. Karagöz,
    EMBO Journal 43 (2024) 4668–4698.
date_created: 2024-09-15T22:01:42Z
date_published: 2024-10-15T00:00:00Z
date_updated: 2025-09-08T09:22:11Z
day: '15'
ddc:
- '570'
department:
- _id: MaLo
- _id: JiFr
doi: 10.1038/s44318-024-00207-0
external_id:
  isi:
  - '001306286100002'
  pmid:
  - '39232130'
file:
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month: '10'
oa: 1
oa_version: Published Version
page: 4668-4698
pmid: 1
publication: EMBO Journal
publication_identifier:
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  issn:
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publication_status: published
publisher: Embo Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced
  clustering
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 43
year: '2024'
...
---
OA_place: publisher
_id: '18076'
abstract:
- lang: eng
  text: "The new era of Ge has opened up new possibilities in quantum computing. The
    maturity of Ge\r\nspin qubits is unquestioned, while hybrid semiconductor-superconductor
    Ge circuits are on track\r\nto enter the game. Gate-tunable transmons (gatemons)
    employing semiconductor Josephson\r\njunctions have recently emerged as building
    blocks for such hybrid quantum circuits. In this\r\nthesis, we present a gatemon
    fabricated in planar Germanium. We induce superconductivity\r\nin a two-dimensional
    hole gas by evaporating aluminum atop a thin spacer, which separates\r\nthe superconductor
    from the Ge quantum well. The Josephson junction is then integrated\r\ninto an
    Xmon circuit and capacitively coupled to a transmission line resonator. We showcase\r\nthe
    qubit tunability in a broad frequency range with resonator and two-tone spectroscopy.\r\nTime-domain
    characterizations reveal energy relaxation and coherence times up to 75 ns. Our\r\nresults,
    combined with the recent advances in the spin qubit field, pave the way towards
    novel\r\nhybrid and protected qubits in a group IV, CMOS-compatible material."
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Oliver
  full_name: Sagi, Oliver
  id: 71616374-A8E9-11E9-A7CA-09ECE5697425
  last_name: Sagi
citation:
  ama: Sagi O. Hybrid circuits on planar Germanium. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18076">10.15479/at:ista:18076</a>
  apa: Sagi, O. (2024). <i>Hybrid circuits on planar Germanium</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18076">https://doi.org/10.15479/at:ista:18076</a>
  chicago: Sagi, Oliver. “Hybrid Circuits on Planar Germanium.” Institute of Science
    and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18076">https://doi.org/10.15479/at:ista:18076</a>.
  ieee: O. Sagi, “Hybrid circuits on planar Germanium,” Institute of Science and Technology
    Austria, 2024.
  ista: Sagi O. 2024. Hybrid circuits on planar Germanium. Institute of Science and
    Technology Austria.
  mla: Sagi, Oliver. <i>Hybrid Circuits on Planar Germanium</i>. Institute of Science
    and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18076">10.15479/at:ista:18076</a>.
  short: O. Sagi, Hybrid Circuits on Planar Germanium, Institute of Science and Technology
    Austria, 2024.
corr_author: '1'
date_created: 2024-09-16T12:58:36Z
date_published: 2024-09-18T00:00:00Z
date_updated: 2026-04-16T12:20:39Z
day: '18'
ddc:
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: GeKa
doi: 10.15479/at:ista:18076
ec_funded: 1
file:
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  file_id: '18094'
  file_name: Thesis_OliverSagi.zip
  file_size: 172098524
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file_date_updated: 2024-09-19T09:20:33Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: '111'
project:
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
- _id: c0977eea-5a5b-11eb-8a69-a862db0cf4d1
  grant_number: I05060
  name: High impedance circuit quantum electrodynamics with hole spins
- _id: 262116AA-B435-11E9-9278-68D0E5697425
  name: Hybrid Semiconductor - Superconductor Quantum Devices
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17202'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
title: Hybrid circuits on planar Germanium
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
_id: '18086'
abstract:
- lang: eng
  text: "Abstract. Continuous group key agreement (CGKA) allows a group of\r\nusers
    to maintain a continuously updated shared key in an asynchronous\r\nsetting where
    parties only come online sporadically and their messages\r\nare relayed by an
    untrusted server. CGKA captures the basic primitive\r\nunderlying group messaging
    schemes.\r\nCurrent solutions including TreeKEM (“Messaging Layer Security”\r\n(MLS)
    IETF RFC 9420) cannot handle concurrent requests while retaining low communication
    complexity. The exception being CoCoA, which\r\nis concurrent while having extremely
    low communication complexity (in\r\ngroups of size n and for m concurrent updates
    the communication per\r\nuser is log(n), i.e., independent of m). The main downside
    of CoCoA\r\nis that in groups of size n, users might have to do up to log(n) update\r\nrequests
    to the server to ensure their (potentially corrupted) key material has been refreshed.\r\nIn
    this work we present a “fast healing” concurrent CGKA protocol,\r\nnamed DeCAF,
    where users will heal after at most log(t) requests, with\r\nt being the number
    of corrupted users. While also suitable for the standard central-server setting,
    our protocol is particularly interesting for\r\nrealizing decentralized group
    messaging, where protocol messages (add,\r\nremove, update) are being posted on
    some append-only data structure\r\nrather than sent to a server. In this setting,
    concurrency is crucial once\r\nthe rate of requests exceeds, say, the rate at
    which new blocks are added\r\nto a blockchain.\r\nIn the central-server setting,
    CoCoA (the only alternative with concurrency, sub-linear communication and basic
    post-compromise security)\r\nenjoys much lower download communication. However,
    in the decentralized setting – where there is no server which can craft specific
    messages\r\nfor different users to reduce their download communication – our protocol\r\nsignificantly
    outperforms CoCoA. DeCAF heals in fewer epochs (log(t)\r\nvs. log(n)) while incurring
    a similar per epoch per user communication\r\ncost."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Joel F
  full_name: Alwen, Joel F
  id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
  last_name: Alwen
- first_name: Benedikt
  full_name: Auerbach, Benedikt
  id: D33D2B18-E445-11E9-ABB7-15F4E5697425
  last_name: Auerbach
  orcid: 0000-0002-7553-6606
- first_name: Miguel
  full_name: Cueto Noval, Miguel
  id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc
  last_name: Cueto Noval
  orcid: 0000-0002-2505-4246
- first_name: Karen
  full_name: Klein, Karen
  id: 3E83A2F8-F248-11E8-B48F-1D18A9856A87
  last_name: Klein
- first_name: Guillermo
  full_name: Pascual Perez, Guillermo
  id: 2D7ABD02-F248-11E8-B48F-1D18A9856A87
  last_name: Pascual Perez
  orcid: 0000-0001-8630-415X
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Alwen JF, Auerbach B, Cueto Noval M, Klein K, Pascual Perez G, Pietrzak KZ.
    DeCAF: Decentralizable CGKA with fast healing. In: Galdi C, Phan DH, eds. <i>Security
    and Cryptography for Networks: 14th International Conference</i>. Vol 14974. Cham:
    Springer Nature; 2024:294–313. doi:<a href="https://doi.org/10.1007/978-3-031-71073-5_14">10.1007/978-3-031-71073-5_14</a>'
  apa: 'Alwen, J. F., Auerbach, B., Cueto Noval, M., Klein, K., Pascual Perez, G.,
    &#38; Pietrzak, K. Z. (2024). DeCAF: Decentralizable CGKA with fast healing. In
    C. Galdi &#38; D. H. Phan (Eds.), <i>Security and Cryptography for Networks: 14th
    International Conference</i> (Vol. 14974, pp. 294–313). Cham: Springer Nature.
    <a href="https://doi.org/10.1007/978-3-031-71073-5_14">https://doi.org/10.1007/978-3-031-71073-5_14</a>'
  chicago: 'Alwen, Joel F, Benedikt Auerbach, Miguel Cueto Noval, Karen Klein, Guillermo
    Pascual Perez, and Krzysztof Z Pietrzak. “DeCAF: Decentralizable CGKA with Fast
    Healing.” In <i>Security and Cryptography for Networks: 14th International Conference</i>,
    edited by Clemente Galdi and Duong Hieu Phan, 14974:294–313. Cham: Springer Nature,
    2024. <a href="https://doi.org/10.1007/978-3-031-71073-5_14">https://doi.org/10.1007/978-3-031-71073-5_14</a>.'
  ieee: 'J. F. Alwen, B. Auerbach, M. Cueto Noval, K. Klein, G. Pascual Perez, and
    K. Z. Pietrzak, “DeCAF: Decentralizable CGKA with fast healing,” in <i>Security
    and Cryptography for Networks: 14th International Conference</i>, Amalfi, Italy,
    2024, vol. 14974, pp. 294–313.'
  ista: 'Alwen JF, Auerbach B, Cueto Noval M, Klein K, Pascual Perez G, Pietrzak KZ.
    2024. DeCAF: Decentralizable CGKA with fast healing. Security and Cryptography
    for Networks: 14th International Conference. SCN: Security and Cryptography for
    Networks, LNCS, vol. 14974, 294–313.'
  mla: 'Alwen, Joel F., et al. “DeCAF: Decentralizable CGKA with Fast Healing.” <i>Security
    and Cryptography for Networks: 14th International Conference</i>, edited by Clemente
    Galdi and Duong Hieu Phan, vol. 14974, Springer Nature, 2024, pp. 294–313, doi:<a
    href="https://doi.org/10.1007/978-3-031-71073-5_14">10.1007/978-3-031-71073-5_14</a>.'
  short: 'J.F. Alwen, B. Auerbach, M. Cueto Noval, K. Klein, G. Pascual Perez, K.Z.
    Pietrzak, in:, C. Galdi, D.H. Phan (Eds.), Security and Cryptography for Networks:
    14th International Conference, Springer Nature, Cham, 2024, pp. 294–313.'
conference:
  end_date: 2024-09-13
  location: Amalfi, Italy
  name: 'SCN: Security and Cryptography for Networks'
  start_date: 2024-09-11
corr_author: '1'
date_created: 2024-09-18T11:35:14Z
date_published: 2024-09-10T00:00:00Z
date_updated: 2026-04-07T13:01:26Z
day: '10'
department:
- _id: GradSch
- _id: KrPi
doi: 10.1007/978-3-031-71073-5_14
editor:
- first_name: Clemente
  full_name: Galdi, Clemente
  last_name: Galdi
- first_name: Duong Hieu
  full_name: Phan, Duong Hieu
  last_name: Phan
external_id:
  isi:
  - '001330408000014'
intvolume: '     14974'
isi: 1
language:
- iso: eng
month: '09'
oa_version: None
page: 294–313
place: Cham
publication: 'Security and Cryptography for Networks: 14th International Conference'
publication_identifier:
  eisbn:
  - '9783031710735'
  eissn:
  - 1611-3349
  isbn:
  - '9783031710728'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '18088'
    relation: dissertation_contains
    status: public
status: public
title: 'DeCAF: Decentralizable CGKA with fast healing'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 14974
year: '2024'
...
---
APC_amount: 3028,31 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18087'
abstract:
- lang: eng
  text: We present a theory describing the interaction of structured light, such as
    light carrying orbital angular momentum, with molecules. The light-matter interaction
    Hamiltonian we derive is expressed through couplings between spherical gradients
    of the electric field and the (transition) electric multipole moments of a particle
    of any nontrivial rotation point group. Our model can therefore accommodate an
    arbitrary complexity of the molecular and electric field structure, and it can
    be straightforwardly extended to atoms or nanostructures. Applying this framework
    to rovibrational spectroscopy of molecules, we uncover the general mechanism of
    angular momentum exchange between the spin and orbital angular momenta of light,
    molecular rotation, and its center-of-mass motion. We show that the nonzero vorticity
    of Laguerre-Gaussian beams can strongly enhance certain rovibrational transitions
    that are considered forbidden in the case of nonhelical light. We discuss the
    experimental requirements for the observation of these forbidden transitions in
    state-of-the-art spatially resolved spectroscopy measurements.
acknowledgement: We are grateful to Emilio Pisanty and Philipp Lunt for valuable discussions.
  This research was funded wholly or in part by the Austrian Science Fund (FWF) [10.55776/F1004].
  G.M.K. gratefully acknowledges funding from the European Union’s Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.
  M.L. acknowledges support by the European Research Council (ERC) Starting Grant
  No. 801770 (ANGULON). O.H.H. acknowledges support by the Austrian Science Fund (FWF)
  [10.55776/P36040]. Furthermore, the financial support by the Austrian Federal Ministry
  for Digital and Economic Affairs, the National Foundation for Research, Technology
  and Development, and the Christian Doppler Research Association is gratefully acknowledged.
article_number: '033277'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Mikhail
  full_name: Maslov, Mikhail
  id: 2E65BB0E-F248-11E8-B48F-1D18A9856A87
  last_name: Maslov
  orcid: 0000-0003-4074-2570
- first_name: Georgios
  full_name: Koutentakis, Georgios
  id: d7b23d3a-9e21-11ec-b482-f76739596b95
  last_name: Koutentakis
- first_name: Mateja
  full_name: Hrast, Mateja
  id: 48dbb294-2a9c-11ef-905d-f56be71f0e5d
  last_name: Hrast
- first_name: Oliver H.
  full_name: Heckl, Oliver H.
  last_name: Heckl
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
citation:
  ama: Maslov M, Koutentakis G, Hrast M, Heckl OH, Lemeshko M. Theory of angular momentum
    transfer from light to molecules. <i>Physical Review Research</i>. 2024;6(3).
    doi:<a href="https://doi.org/10.1103/physrevresearch.6.033277">10.1103/physrevresearch.6.033277</a>
  apa: Maslov, M., Koutentakis, G., Hrast, M., Heckl, O. H., &#38; Lemeshko, M. (2024).
    Theory of angular momentum transfer from light to molecules. <i>Physical Review
    Research</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevresearch.6.033277">https://doi.org/10.1103/physrevresearch.6.033277</a>
  chicago: Maslov, Mikhail, Georgios Koutentakis, Mateja Hrast, Oliver H. Heckl, and
    Mikhail Lemeshko. “Theory of Angular Momentum Transfer from Light to Molecules.”
    <i>Physical Review Research</i>. American Physical Society, 2024. <a href="https://doi.org/10.1103/physrevresearch.6.033277">https://doi.org/10.1103/physrevresearch.6.033277</a>.
  ieee: M. Maslov, G. Koutentakis, M. Hrast, O. H. Heckl, and M. Lemeshko, “Theory
    of angular momentum transfer from light to molecules,” <i>Physical Review Research</i>,
    vol. 6, no. 3. American Physical Society, 2024.
  ista: Maslov M, Koutentakis G, Hrast M, Heckl OH, Lemeshko M. 2024. Theory of angular
    momentum transfer from light to molecules. Physical Review Research. 6(3), 033277.
  mla: Maslov, Mikhail, et al. “Theory of Angular Momentum Transfer from Light to
    Molecules.” <i>Physical Review Research</i>, vol. 6, no. 3, 033277, American Physical
    Society, 2024, doi:<a href="https://doi.org/10.1103/physrevresearch.6.033277">10.1103/physrevresearch.6.033277</a>.
  short: M. Maslov, G. Koutentakis, M. Hrast, O.H. Heckl, M. Lemeshko, Physical Review
    Research 6 (2024).
corr_author: '1'
date_created: 2024-09-18T11:43:16Z
date_published: 2024-09-10T00:00:00Z
date_updated: 2026-04-07T11:52:53Z
day: '10'
ddc:
- '530'
department:
- _id: GradSch
- _id: MiLe
doi: 10.1103/physrevresearch.6.033277
ec_funded: 1
external_id:
  arxiv:
  - '2310.00095'
file:
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issue: '3'
language:
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month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 7c040762-9f16-11ee-852c-dd79eeee4ab3
  grant_number: F100403
  name: Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '801770'
  name: 'Angulon: physics and applications of a new quasiparticle'
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
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publication: Physical Review Research
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publication_status: published
publisher: American Physical Society
quality_controlled: '1'
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title: Theory of angular momentum transfer from light to molecules
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OA_place: publisher
_id: '18088'
abstract:
- lang: eng
  text: "Instant messaging applications like Whatsapp, Signal or Telegram have become
    ubiquitous in today's society.\r\nMany of them provide not only end-to-end encryption,
    but also security guarantees even when the key material gets compromised.\r\nThese
    are achieved through frequent key update performed by users.\r\nIn particular,
    the compromise of a group key should preserve confidentiality of previously exchanged
    messages (forward secrecy), and a subsequent key update will ensure security for
    future ones (post-compromise security).\r\nThough great protocols for one-on-one
    communication have been known for some time, the design of ones that scale efficiently
    for larger groups while achieving akin security guarantees is a hard problem.\r\nA
    great deal of research has been aimed at this topic, much of it under the umbrella
    of the Messaging Layer Security (MLS) working group at the IETF. \r\nStarted in
    2018, this joint effort by academics and industry culminated in 2023 with the
    publication of the first standard for secure group messaging [IETF, RFC9420].\r\n\r\nAt
    the core of secure group messaging is a cryptographic primitive termed Continuous
    Group Key Agreement, or CGKA [Alwen et al. 2021], that essentially allows a changing
    group of users to agree on a common key with the added functionality security
    against compromises is achieved by users asynchronously issuing a key update.
    In this thesis we contribute to the understanding of CGKA across different angles.\r\nFirst,
    we present a new technique to effect dynamic operations in groups, i.e., add or
    remove members, that can be more efficient that the one employed by MLS in certain
    settings.\r\nConsidering the setting of users belonging to multiple overlapping
    groups, we then show lowerbounds on the communication cost of constructions that
    leverage said overlap, at the same time showing protocols that are asymptotically
    optimal and efficient for practical settings, respectively. Along the way, we
    show that the communication cost of key updates in MLS is average-cost optimal.\r\nAn
    important feature in CGKA protocols, particularly for big groups, is the possibility
    of executing several group operations concurrently. While later versions of MLS
    support this, they do at the cost of worsening the communication efficiency of
    future group operations.\r\nIn this thesis we introduce two new protocols that
    permit concurrency without any negative effect on efficiency. Our protocols circumvent
    previously existing lower bounds by satisfying a new notion of post-compromise
    security that only asks for security to be re-established after a certain number
    of key updates have taken place. While this can be slower than MLS in terms of
    rounds of communication, we show that it leads to more efficient overall communication.
    \r\nAdditionally, we introduce a new technique that allows group members to decrease
    the information they need to store and download, which makes one of our protocols
    enjoy much lower download cost than any other existing CGKA constructions. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Guillermo
  full_name: Pascual Perez, Guillermo
  id: 2D7ABD02-F248-11E8-B48F-1D18A9856A87
  last_name: Pascual Perez
  orcid: 0000-0001-8630-415X
citation:
  ama: Pascual Perez G. On the efficiency and security of secure group messaging.
    2024. doi:<a href="https://doi.org/10.15479/at:ista:18088">10.15479/at:ista:18088</a>
  apa: Pascual Perez, G. (2024). <i>On the efficiency and security of secure group
    messaging</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18088">https://doi.org/10.15479/at:ista:18088</a>
  chicago: Pascual Perez, Guillermo. “On the Efficiency and Security of Secure Group
    Messaging.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18088">https://doi.org/10.15479/at:ista:18088</a>.
  ieee: G. Pascual Perez, “On the efficiency and security of secure group messaging,”
    Institute of Science and Technology Austria, 2024.
  ista: Pascual Perez G. 2024. On the efficiency and security of secure group messaging.
    Institute of Science and Technology Austria.
  mla: Pascual Perez, Guillermo. <i>On the Efficiency and Security of Secure Group
    Messaging</i>. Institute of Science and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18088">10.15479/at:ista:18088</a>.
  short: G. Pascual Perez, On the Efficiency and Security of Secure Group Messaging,
    Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-09-18T12:59:49Z
date_published: 2024-09-18T00:00:00Z
date_updated: 2026-04-07T13:01:26Z
day: '18'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: KrPi
- _id: GradSch
doi: 10.15479/at:ista:18088
ec_funded: 1
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  file_size: 11917734
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has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '239'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
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    relation: part_of_dissertation
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  - id: '18086'
    relation: part_of_dissertation
    status: public
  - id: '10049'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
title: On the efficiency and security of secure group messaging
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year: '2024'
...
---
_id: '18097'
abstract:
- lang: eng
  text: "In our companion paper \"Tight bounds for the learning of homotopy à la Niyogi,
    Smale, and Weinberger for subsets of Euclidean spaces and of Riemannian manifolds\"
    we gave optimal bounds (in terms of the two one-sided Hausdorff distances) on
    a sample P of an input shape \U0001D4AE (either manifold or general set with positive
    reach) such that one can infer the homotopy of \U0001D4AE from the union of balls
    with some radius centred at P, both in Euclidean space and in a Riemannian manifold
    of bounded curvature. The construction showing the optimality of the bounds is
    not straightforward. The purpose of this video is to visualize and thus elucidate
    said construction in the Euclidean setting."
acknowledgement: "This research has been supported by the European Research Council
  (ERC), grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF),
  grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian
  Science Fund (FWF), grant No. I02979-N35. Mathijs Wintraecken: Supported by the
  European Union’s Horizon 2020 research and innovation programme under the Marie
  Skłodowska-Curie grant agreement No. 754411, the Austrian science fund (FWF) grant
  No. M-3073, and the welcome package from IDEX of the Université Côte d’Azur.\r\nWe
  thank Jean-Daniel Boissonnat, Herbert Edelsbrunner, and Mariette Yvinec for discussion."
alternative_title:
- LIPIcs
article_number: '87'
article_processing_charge: Yes
author:
- first_name: Dominique
  full_name: Attali, Dominique
  last_name: Attali
- first_name: Hana
  full_name: Kourimska, Hana
  id: D9B8E14C-3C26-11EA-98F5-1F833DDC885E
  last_name: Kourimska
  orcid: 0000-0001-7841-0091
- first_name: Christopher D
  full_name: Fillmore, Christopher D
  id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
  last_name: Fillmore
- first_name: Ishika
  full_name: Ghosh, Ishika
  id: ee449b28-344d-11ef-a6d5-9ca430e9e9ff
  last_name: Ghosh
- first_name: Andre
  full_name: Lieutier, Andre
  last_name: Lieutier
- first_name: Elizabeth R
  full_name: Stephenson, Elizabeth R
  id: 2D04F932-F248-11E8-B48F-1D18A9856A87
  last_name: Stephenson
  orcid: 0000-0002-6862-208X
- first_name: Mathijs
  full_name: Wintraecken, Mathijs
  id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
  last_name: Wintraecken
  orcid: 0000-0002-7472-2220
citation:
  ama: 'Attali D, Kourimska H, Fillmore CD, et al. The ultimate frontier: An optimality
    construction for homotopy inference (media exposition). In: <i>40th International
    Symposium on Computational Geometry</i>. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik; 2024. doi:<a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.87">10.4230/LIPIcs.SoCG.2024.87</a>'
  apa: 'Attali, D., Kourimska, H., Fillmore, C. D., Ghosh, I., Lieutier, A., Stephenson,
    E. R., &#38; Wintraecken, M. (2024). The ultimate frontier: An optimality construction
    for homotopy inference (media exposition). In <i>40th International Symposium
    on Computational Geometry</i> (Vol. 293). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.87">https://doi.org/10.4230/LIPIcs.SoCG.2024.87</a>'
  chicago: 'Attali, Dominique, Hana Kourimska, Christopher D Fillmore, Ishika Ghosh,
    Andre Lieutier, Elizabeth R Stephenson, and Mathijs Wintraecken. “The Ultimate
    Frontier: An Optimality Construction for Homotopy Inference (Media Exposition).”
    In <i>40th International Symposium on Computational Geometry</i>, Vol. 293. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2024. <a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.87">https://doi.org/10.4230/LIPIcs.SoCG.2024.87</a>.'
  ieee: 'D. Attali <i>et al.</i>, “The ultimate frontier: An optimality construction
    for homotopy inference (media exposition),” in <i>40th International Symposium
    on Computational Geometry</i>, Athens, Greece, 2024, vol. 293.'
  ista: 'Attali D, Kourimska H, Fillmore CD, Ghosh I, Lieutier A, Stephenson ER, Wintraecken
    M. 2024. The ultimate frontier: An optimality construction for homotopy inference
    (media exposition). 40th International Symposium on Computational Geometry. SoCG:
    Symposium on Computational Geometry, LIPIcs, vol. 293, 87.'
  mla: 'Attali, Dominique, et al. “The Ultimate Frontier: An Optimality Construction
    for Homotopy Inference (Media Exposition).” <i>40th International Symposium on
    Computational Geometry</i>, vol. 293, 87, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2024, doi:<a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.87">10.4230/LIPIcs.SoCG.2024.87</a>.'
  short: D. Attali, H. Kourimska, C.D. Fillmore, I. Ghosh, A. Lieutier, E.R. Stephenson,
    M. Wintraecken, in:, 40th International Symposium on Computational Geometry, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2024.
conference:
  end_date: 2024-06-14
  location: Athens, Greece
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2024-06-11
corr_author: '1'
date_created: 2024-09-19T10:29:48Z
date_published: 2024-06-06T00:00:00Z
date_updated: 2025-04-15T07:16:58Z
day: '06'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.4230/LIPIcs.SoCG.2024.87
ec_funded: 1
file:
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file_date_updated: 2024-09-19T10:30:37Z
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intvolume: '       293'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: Mathematics, Computer Science
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
  grant_number: M03073
  name: Learning and triangulating manifolds via collapses
publication: 40th International Symposium on Computational Geometry
publication_identifier:
  isbn:
  - '9783959773164'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
status: public
title: 'The ultimate frontier: An optimality construction for homotopy inference (media
  exposition)'
tmp:
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  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 293
year: '2024'
...
---
_id: '18107'
abstract:
- lang: eng
  text: We consider a dilute fully spin-polarized Fermi gas at positive temperature
    in dimensions  d∈{1,2,3} . We show that the pressure of the interacting gas is
    bounded from below by that of the free gas plus, to leading order, an explicit
    term of order  adρ2+2/d, where a is the p-wave scattering length of the repulsive
    interaction and  ρ  is the particle density. The results are valid for a wide
    range of repulsive interactions, including that of a hard core, and uniform in
    temperatures at most of the order of the Fermi temperature. A central ingredient
    in the proof is a rigorous implementation of the fermionic cluster expansion of
    Gaudin, Gillespie and Ripka (Nucl. Phys. A, 176.2 (1971), pp. 237–260).
acknowledgement: 'Financial support by the Austrian Science Fund (FWF) through grant
  DOI: 10.55776/I6427 (as part of the SFB/TRR 352) is gratefully acknowledged.'
article_number: e78
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Asbjørn Bækgaard
  full_name: Lauritsen, Asbjørn Bækgaard
  id: e1a2682f-dc8d-11ea-abe3-81da9ac728f1
  last_name: Lauritsen
  orcid: 0000-0003-4476-2288
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: 'Lauritsen AB, Seiringer R. Pressure of a dilute spin-polarized Fermi gas:
    Lower bound. <i>Forum of Mathematics, Sigma</i>. 2024;12. doi:<a href="https://doi.org/10.1017/fms.2024.56">10.1017/fms.2024.56</a>'
  apa: 'Lauritsen, A. B., &#38; Seiringer, R. (2024). Pressure of a dilute spin-polarized
    Fermi gas: Lower bound. <i>Forum of Mathematics, Sigma</i>. Cambridge University
    Press. <a href="https://doi.org/10.1017/fms.2024.56">https://doi.org/10.1017/fms.2024.56</a>'
  chicago: 'Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Pressure of a Dilute
    Spin-Polarized Fermi Gas: Lower Bound.” <i>Forum of Mathematics, Sigma</i>. Cambridge
    University Press, 2024. <a href="https://doi.org/10.1017/fms.2024.56">https://doi.org/10.1017/fms.2024.56</a>.'
  ieee: 'A. B. Lauritsen and R. Seiringer, “Pressure of a dilute spin-polarized Fermi
    gas: Lower bound,” <i>Forum of Mathematics, Sigma</i>, vol. 12. Cambridge University
    Press, 2024.'
  ista: 'Lauritsen AB, Seiringer R. 2024. Pressure of a dilute spin-polarized Fermi
    gas: Lower bound. Forum of Mathematics, Sigma. 12, e78.'
  mla: 'Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Pressure of a Dilute Spin-Polarized
    Fermi Gas: Lower Bound.” <i>Forum of Mathematics, Sigma</i>, vol. 12, e78, Cambridge
    University Press, 2024, doi:<a href="https://doi.org/10.1017/fms.2024.56">10.1017/fms.2024.56</a>.'
  short: A.B. Lauritsen, R. Seiringer, Forum of Mathematics, Sigma 12 (2024).
corr_author: '1'
date_created: 2024-09-20T12:25:25Z
date_published: 2024-09-09T00:00:00Z
date_updated: 2026-04-07T13:01:40Z
day: '09'
ddc:
- '510'
department:
- _id: GradSch
- _id: RoSe
doi: 10.1017/fms.2024.56
external_id:
  arxiv:
  - '2407.05990'
  isi:
  - '001307817400001'
file:
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  date_created: 2024-09-23T09:56:17Z
  date_updated: 2024-09-23T09:56:17Z
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  file_name: 2024_ForumMath_Lauritsen.pdf
  file_size: 599886
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  success: 1
file_date_updated: 2024-09-23T09:56:17Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: bda63fe5-d553-11ed-ba76-a16e3d2f256b
  grant_number: I06427
  name: Mathematical Challenges in BCS Theory of Superconductivity
publication: Forum of Mathematics, Sigma
publication_identifier:
  issn:
  - 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
related_material:
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  - id: '18135'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'Pressure of a dilute spin-polarized Fermi gas: Lower bound'
tmp:
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  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 12
year: '2024'
...
---
APC_amount: 2742,92 EUR
OA_place: publisher
OA_type: hybrid
_id: '18108'
abstract:
- lang: eng
  text: Here we announce the construction and properties of a big commutative subalgebra
    of the Kirillov algebra attached to a finite dimensional irreducible representation
    of a complex semisimple Lie group. They are commutative finite flat algebras over
    the cohomology of the classifying space of the group. They are isomorphic with
    the equivariant intersection cohomology of affine Schubert varieties, endowing
    the latter with a new ring structure. Study of the finer aspects of the structure
    of the big algebras will also furnish the stalks of the intersection cohomology
    with ring structure, thus ringifying Lusztig’s q-weight multiplicity polynomials
    i.e., certain affine Kazhdan–Lusztig polynomials.
acknowledgement: "We thank Nigel Hitchin for discussions and the joint projects this
  paper has grown out from. We thank Vladyslav Zveryk for collaboration on Theorem
  2.3 and on the corresponding Magma code which implements big algebras. We thank
  Hiraku Nakajima for discussions and pointing out Theorem 3.1.2, a result generalizing
  our original observation in the= = 0 case. Special thanks go to Leonid Rybnikov
  for patiently explaining his works, in particular crucial to Theorem 2.1. We thank
  Michel Brion, Michael Finkelberg, Oscar García-Prada, Jakub Löwit, Joel Kamnitzer,
  Friedrich Knop, Michael McBreen, Anton Mellit, Takuro Mochizuki, Shon Ngô, Kamil
  Rychlewicz, Shiyu Shen, Leslie Spencer, Balázs Szendr ˝ oi, András Szenes, and Oksana\r\nYakimova
  for comments and discussions. Kamil Rychlewicz and Daniel Bedats helped with the
  Mathematica files for the figures, and we used the SM_isospin Tikz package of Izaak
  Neutelings for drawing the baryon multiplets. We thank the referees for many useful
  comments. We acknowledge funding from FWF grant “Geometry of the tip of the global
  nilpotent cone” no. P 35847."
article_number: e2319341121
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Tamás
  full_name: Hausel, Tamás
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
  orcid: 0000-0002-9582-2634
citation:
  ama: Hausel T. Commutative avatars of representations of semisimple Lie groups.
    <i>Proceedings of the National Academy of Sciences of the United States of America</i>.
    2024;121(38). doi:<a href="https://doi.org/10.1073/pnas.2319341121">10.1073/pnas.2319341121</a>
  apa: Hausel, T. (2024). Commutative avatars of representations of semisimple Lie
    groups. <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.2319341121">https://doi.org/10.1073/pnas.2319341121</a>
  chicago: Hausel, Tamás. “Commutative Avatars of Representations of Semisimple Lie
    Groups.” <i>Proceedings of the National Academy of Sciences of the United States
    of America</i>. National Academy of Sciences, 2024. <a href="https://doi.org/10.1073/pnas.2319341121">https://doi.org/10.1073/pnas.2319341121</a>.
  ieee: T. Hausel, “Commutative avatars of representations of semisimple Lie groups,”
    <i>Proceedings of the National Academy of Sciences of the United States of America</i>,
    vol. 121, no. 38. National Academy of Sciences, 2024.
  ista: Hausel T. 2024. Commutative avatars of representations of semisimple Lie groups.
    Proceedings of the National Academy of Sciences of the United States of America.
    121(38), e2319341121.
  mla: Hausel, Tamás. “Commutative Avatars of Representations of Semisimple Lie Groups.”
    <i>Proceedings of the National Academy of Sciences of the United States of America</i>,
    vol. 121, no. 38, e2319341121, National Academy of Sciences, 2024, doi:<a href="https://doi.org/10.1073/pnas.2319341121">10.1073/pnas.2319341121</a>.
  short: T. Hausel, Proceedings of the National Academy of Sciences of the United
    States of America 121 (2024).
corr_author: '1'
date_created: 2024-09-22T22:01:41Z
date_published: 2024-09-17T00:00:00Z
date_updated: 2025-05-08T09:57:59Z
day: '17'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1073/pnas.2319341121
external_id:
  pmid:
  - '39259592'
file:
- access_level: open_access
  checksum: df80c873633c6734d2e324841e69db58
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-23T11:22:56Z
  date_updated: 2024-09-23T11:22:56Z
  file_id: '18127'
  file_name: 2024_PNAS_Hausel.pdf
  file_size: 3764695
  relation: main_file
  success: 1
file_date_updated: 2024-09-23T11:22:56Z
has_accepted_license: '1'
intvolume: '       121'
issue: '38'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3
  grant_number: P35847
  name: Geometry of the tip of the global nilpotent cone
publication: Proceedings of the National Academy of Sciences of the United States
  of America
publication_identifier:
  eissn:
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  link:
  - relation: press_release
    url: https://ista.ac.at/en/news/big-algebras-a-dictionary-of-abstract-math/
scopus_import: '1'
status: public
title: Commutative avatars of representations of semisimple Lie groups
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 121
year: '2024'
...
---
_id: '18109'
abstract:
- lang: eng
  text: Venous thromboembolism (VTE) is a common, deadly disease with an increasing
    incidence despite preventive efforts. Clinical observations have associated elevated
    antibody concentrations or antibody-based therapies with thrombotic events. However,
    how antibodies contribute to thrombosis is unknown. Here, we show that reduced
    blood flow enabled immunoglobulin M (IgM) to bind to FcμR and the polymeric immunoglobulin
    receptor (pIgR), initiating endothelial activation and platelet recruitment. Subsequently,
    the procoagulant surface of activated platelets accommodated antigen- and FcγR-independent
    IgG deposition. This leads to classical complement activation, setting in motion
    a prothrombotic vicious circle. Key elements of this mechanism were present in
    humans in the setting of venous stasis as well as in the dysregulated immunothrombosis
    of COVID-19. This antibody-driven thrombosis can be prevented by pharmacologically
    targeting complement. Hence, our results uncover antibodies as previously unrecognized
    central regulators of thrombosis. These findings carry relevance for therapeutic
    application of antibodies and open innovative avenues to target thrombosis without
    compromising hemostasis.
acknowledgement: "We thank Michael Carroll (Harvard Medical School, Boston) for providing
  Ighmtm1Che, C4−/−, and C3−/− mice; Mark Suter (University of Zurich, Zurich) for
  providing Aicda−/− mice; Marina Botto (Imperial College London, London) for providing
  C1q−/− and fB−/− mice; Craig Gerard (Harvard Medical School, Boston) for providing
  C3aR−/− mice; Falk Nimmerjahn (University Erlangen-Nuernberg, Erlangen) for providing
  Fcgr−/−Fcgr2b−/− mice; Karl Lang (University of Duisburg-Essen, Essen) for providing
  Fcmr−/− mice; Hans Hengartner and Rolf Zinkernagel (ETH Zurich, Zurich) for providing
  KL25 mice; Mark Zabel (University Hospital of Zurich, Zurich) for providing CR2−/−
  mice; Christie Ballantyne (Baylor College of Medicine, Houston) for providing CD11c−/−
  mice; and Siamon Gordon (University of Oxford, Oxford) for providing CD11b−/− mice.
  A.V. wishes to thank Michael Grünaug and dedicates this work to Annette, Rita, and
  Hans.\r\nThis project has received funding from the European Research Council (ERC)
  under the European Union’s Horizon 2020 research and innovation programme (grant
  agreement no. \r\n947611) (K.S.). This study was supported by the Deutsche Forschungsgemeinschaft
  through the collaborative research center 914 project B02 (K.S. and S.M.), project
  B04 (A.V.), project A01 (M.M.), project B01 (M.S.), the collaborative research center
  1123 project B07 (K.S. and S.M.), the collaborative research center 359 (project
  A03 [K.S.] and B02 [M.S.]), the international research training group 1911 project
  B09 (A.V.), the clinical research unit 303 project 7 (A.V.), cluster of excellence
  2167 (A.V.), collaborative research center 1526 project 05 (A.V.), the ANR-DFG project
  JAKPOT (K.S.), LMUexcellent (K.S.), and the Deutsche Zentrum für Herz-Kreislauf-Forschung
  (PostDoc Grant and partner site project [K.S. and S.M.]). M.I. is supported by the
  European Research Council (ERC) Advanced Grant 101141363, ERC Proof of Concept Grant
  101138728, Italian Association for Cancer Research (AIRC) Grants 19891 and \r\n22737,
  Italian Ministry for University and Research Grants PE00000007 (INF-ACT) and PRIN
  \r\n2022FMESXL, Funded Research Agreement from Asher Biotherapeutics, VIR Biotechnology,
  and BlueJay Therapeutics. V.F. is supported by the Italian Ministry for University
  and Research Grants PE00000007 (INF-ACT) and Fondazione Prossimo Mio."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Konstantin
  full_name: Stark, Konstantin
  last_name: Stark
- first_name: Badr
  full_name: Kilani, Badr
  last_name: Kilani
- first_name: Sven
  full_name: Stockhausen, Sven
  last_name: Stockhausen
- first_name: Johanna
  full_name: Busse, Johanna
  last_name: Busse
- first_name: Irene
  full_name: Schubert, Irene
  last_name: Schubert
- first_name: Thuy Duong
  full_name: Tran, Thuy Duong
  last_name: Tran
- first_name: Florian R
  full_name: Gärtner, Florian R
  id: 397A88EE-F248-11E8-B48F-1D18A9856A87
  last_name: Gärtner
  orcid: 0000-0001-6120-3723
- first_name: Alexander
  full_name: Leunig, Alexander
  last_name: Leunig
- first_name: Kami
  full_name: Pekayvaz, Kami
  last_name: Pekayvaz
- first_name: Leo
  full_name: Nicolai, Leo
  last_name: Nicolai
- first_name: Valeria
  full_name: Fumagalli, Valeria
  last_name: Fumagalli
- first_name: Julia
  full_name: Stermann, Julia
  last_name: Stermann
- first_name: Felix
  full_name: Stephan, Felix
  last_name: Stephan
- first_name: Christian
  full_name: David, Christian
  last_name: David
- first_name: Martin B.
  full_name: Müller, Martin B.
  last_name: Müller
- first_name: Birgitta
  full_name: Heyman, Birgitta
  last_name: Heyman
- first_name: Anja
  full_name: Lux, Anja
  last_name: Lux
- first_name: Alexandra
  full_name: Da Palma Guerreiro, Alexandra
  last_name: Da Palma Guerreiro
- first_name: Lukas P.
  full_name: Frenzel, Lukas P.
  last_name: Frenzel
- first_name: Christoph Q.
  full_name: Schmidt, Christoph Q.
  last_name: Schmidt
- first_name: Arthur
  full_name: Dopler, Arthur
  last_name: Dopler
- first_name: Markus
  full_name: Moser, Markus
  last_name: Moser
- first_name: Sue
  full_name: Chandraratne, Sue
  last_name: Chandraratne
- first_name: Marie Luise
  full_name: Von Brühl, Marie Luise
  last_name: Von Brühl
- first_name: Michael
  full_name: Lorenz, Michael
  last_name: Lorenz
- first_name: Thomas
  full_name: Korff, Thomas
  last_name: Korff
- first_name: Martina
  full_name: Rudelius, Martina
  last_name: Rudelius
- first_name: Oliver
  full_name: Popp, Oliver
  last_name: Popp
- first_name: Marieluise
  full_name: Kirchner, Marieluise
  last_name: Kirchner
- first_name: Philipp
  full_name: Mertins, Philipp
  last_name: Mertins
- first_name: Falk
  full_name: Nimmerjahn, Falk
  last_name: Nimmerjahn
- first_name: Matteo
  full_name: Iannacone, Matteo
  last_name: Iannacone
- first_name: Markus
  full_name: Sperandio, Markus
  last_name: Sperandio
- first_name: Bernd
  full_name: Engelmann, Bernd
  last_name: Engelmann
- first_name: Admar
  full_name: Verschoor, Admar
  last_name: Verschoor
- first_name: Steffen
  full_name: Massberg, Steffen
  last_name: Massberg
citation:
  ama: Stark K, Kilani B, Stockhausen S, et al. Antibodies and complement are key
    drivers of thrombosis. <i>Immunity</i>. 2024;57(9):2140-2156. doi:<a href="https://doi.org/10.1016/j.immuni.2024.08.007">10.1016/j.immuni.2024.08.007</a>
  apa: Stark, K., Kilani, B., Stockhausen, S., Busse, J., Schubert, I., Tran, T. D.,
    … Massberg, S. (2024). Antibodies and complement are key drivers of thrombosis.
    <i>Immunity</i>. Elsevier. <a href="https://doi.org/10.1016/j.immuni.2024.08.007">https://doi.org/10.1016/j.immuni.2024.08.007</a>
  chicago: Stark, Konstantin, Badr Kilani, Sven Stockhausen, Johanna Busse, Irene
    Schubert, Thuy Duong Tran, Florian R Gärtner, et al. “Antibodies and Complement
    Are Key Drivers of Thrombosis.” <i>Immunity</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.immuni.2024.08.007">https://doi.org/10.1016/j.immuni.2024.08.007</a>.
  ieee: K. Stark <i>et al.</i>, “Antibodies and complement are key drivers of thrombosis,”
    <i>Immunity</i>, vol. 57, no. 9. Elsevier, pp. 2140–2156, 2024.
  ista: Stark K, Kilani B, Stockhausen S, Busse J, Schubert I, Tran TD, Gärtner FR,
    Leunig A, Pekayvaz K, Nicolai L, Fumagalli V, Stermann J, Stephan F, David C,
    Müller MB, Heyman B, Lux A, Da Palma Guerreiro A, Frenzel LP, Schmidt CQ, Dopler
    A, Moser M, Chandraratne S, Von Brühl ML, Lorenz M, Korff T, Rudelius M, Popp
    O, Kirchner M, Mertins P, Nimmerjahn F, Iannacone M, Sperandio M, Engelmann B,
    Verschoor A, Massberg S. 2024. Antibodies and complement are key drivers of thrombosis.
    Immunity. 57(9), 2140–2156.
  mla: Stark, Konstantin, et al. “Antibodies and Complement Are Key Drivers of Thrombosis.”
    <i>Immunity</i>, vol. 57, no. 9, Elsevier, 2024, pp. 2140–56, doi:<a href="https://doi.org/10.1016/j.immuni.2024.08.007">10.1016/j.immuni.2024.08.007</a>.
  short: K. Stark, B. Kilani, S. Stockhausen, J. Busse, I. Schubert, T.D. Tran, F.R.
    Gärtner, A. Leunig, K. Pekayvaz, L. Nicolai, V. Fumagalli, J. Stermann, F. Stephan,
    C. David, M.B. Müller, B. Heyman, A. Lux, A. Da Palma Guerreiro, L.P. Frenzel,
    C.Q. Schmidt, A. Dopler, M. Moser, S. Chandraratne, M.L. Von Brühl, M. Lorenz,
    T. Korff, M. Rudelius, O. Popp, M. Kirchner, P. Mertins, F. Nimmerjahn, M. Iannacone,
    M. Sperandio, B. Engelmann, A. Verschoor, S. Massberg, Immunity 57 (2024) 2140–2156.
date_created: 2024-09-22T22:01:42Z
date_published: 2024-09-10T00:00:00Z
date_updated: 2025-09-08T09:50:13Z
day: '10'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1016/j.immuni.2024.08.007
external_id:
  isi:
  - '001317438500001'
  pmid:
  - '39226900'
file:
- access_level: open_access
  checksum: 4683de43d06a8fd8e3fc91af4ddc1ba2
  content_type: application/pdf
  creator: dernst
  date_created: 2024-09-30T09:16:03Z
  date_updated: 2024-09-30T09:16:03Z
  file_id: '18162'
  file_name: 2024_Immunity_Stark.pdf
  file_size: 6892750
  relation: main_file
  success: 1
file_date_updated: 2024-09-30T09:16:03Z
has_accepted_license: '1'
intvolume: '        57'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 2140-2156
pmid: 1
publication: Immunity
publication_identifier:
  eissn:
  - 1097-4180
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Antibodies and complement are key drivers of thrombosis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 57
year: '2024'
...
---
_id: '18110'
abstract:
- lang: eng
  text: We study a chaotic particle-conserving kinetically constrained model, with
    a single parameter which allows us to break reflection symmetry. Through extensive
    numerical simulations we find that the domain wall state shows a variety of dynamical
    behaviors from localization all the way to ballistic transport, depending on the
    value of the reflection breaking parameter. Surprisingly, such anomalous behavior
    is not mirrored in infinite-temperature dynamics, which appear to scale diffusively,
    in line with expectations for generic interacting models. However, studying the
    particle density gradient, we show that the lack of reflection symmetry affects
    infinite-temperature dynamics, resulting in an asymmetric dynamical structure
    factor. This is in disagreement with normal diffusion and suggests that the model
    may also exhibit anomalous dynamics at infinite temperature in the thermodynamic
    limit. Finally, we observe low-entangled eigenstates in the spectrum of the model,
    a telltale sign of quantum many-body scars.
acknowledgement: "The authors acknowledge useful discussions with M. Serbyn, Z. Papic,
  and A. Nunnenkamp. ´\r\nP.B. is supported by the Erwin Schrödinger Center for Quantum
  Science & Technology (ESQ) of the Österreichische Akademie der Wissenschaften (ÖAW)
  under the Discovery Grant. M.L. acknowledges support from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (Grant Agreement\r\nNo. 850899). The numerical simulations were performed using
  the ITensor library [68] on the Vienna Scientific Cluster (VSC)."
article_number: L100304
article_processing_charge: No
article_type: letter_note
arxiv: 1
author:
- first_name: Pietro
  full_name: Brighi, Pietro
  id: 4115AF5C-F248-11E8-B48F-1D18A9856A87
  last_name: Brighi
  orcid: 0000-0002-7969-2729
- first_name: Marko
  full_name: Ljubotina, Marko
  id: F75EE9BE-5C90-11EA-905D-16643DDC885E
  last_name: Ljubotina
  orcid: 0000-0003-0038-7068
citation:
  ama: Brighi P, Ljubotina M. Anomalous transport in the kinetically constrained quantum
    East-West model. <i>Physical Review B</i>. 2024;110(10). doi:<a href="https://doi.org/10.1103/PhysRevB.110.L100304">10.1103/PhysRevB.110.L100304</a>
  apa: Brighi, P., &#38; Ljubotina, M. (2024). Anomalous transport in the kinetically
    constrained quantum East-West model. <i>Physical Review B</i>. American Physical
    Society. <a href="https://doi.org/10.1103/PhysRevB.110.L100304">https://doi.org/10.1103/PhysRevB.110.L100304</a>
  chicago: Brighi, Pietro, and Marko Ljubotina. “Anomalous Transport in the Kinetically
    Constrained Quantum East-West Model.” <i>Physical Review B</i>. American Physical
    Society, 2024. <a href="https://doi.org/10.1103/PhysRevB.110.L100304">https://doi.org/10.1103/PhysRevB.110.L100304</a>.
  ieee: P. Brighi and M. Ljubotina, “Anomalous transport in the kinetically constrained
    quantum East-West model,” <i>Physical Review B</i>, vol. 110, no. 10. American
    Physical Society, 2024.
  ista: Brighi P, Ljubotina M. 2024. Anomalous transport in the kinetically constrained
    quantum East-West model. Physical Review B. 110(10), L100304.
  mla: Brighi, Pietro, and Marko Ljubotina. “Anomalous Transport in the Kinetically
    Constrained Quantum East-West Model.” <i>Physical Review B</i>, vol. 110, no.
    10, L100304, American Physical Society, 2024, doi:<a href="https://doi.org/10.1103/PhysRevB.110.L100304">10.1103/PhysRevB.110.L100304</a>.
  short: P. Brighi, M. Ljubotina, Physical Review B 110 (2024).
corr_author: '1'
date_created: 2024-09-22T22:01:42Z
date_published: 2024-09-11T00:00:00Z
date_updated: 2025-09-08T09:49:29Z
day: '11'
department:
- _id: MaSe
doi: 10.1103/PhysRevB.110.L100304
ec_funded: 1
external_id:
  arxiv:
  - '2405.02102'
  isi:
  - '001361617100003'
intvolume: '       110'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2405.02102
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Anomalous transport in the kinetically constrained quantum East-West model
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 110
year: '2024'
...
---
DOAJ_listed: '1'
_id: '18111'
abstract:
- lang: eng
  text: Observations of tidal disruption events (TDEs) show signs of nitrogen enrichment
    reminiscent of other astrophysical sources such as active galactic nuclei and
    star-forming galaxies. Given that TDEs probe the gas from a single star, it is
    possible to test whether the observed enrichment is consistent with expectations
    from the CNO cycle by looking at the observed nitrogen/carbon (N/C) abundance
    ratios. Given that ≈20% of solar-mass stars (and an even larger fraction of more
    massive stars) live in close binaries, it is worthwhile to also consider what
    TDEs from stars influenced by binary evolution would look like. We show here that
    TDEs from stars stripped of their hydrogen-rich (and nitrogen-poor) envelopes
    through previous binary-induced mass loss can produce much higher observable N/C
    enhancements than even TDEs from massive stars. Additionally, we predict that
    the time dependence of the N/C abundance ratio in the mass fallback rate of stripped
    stars will follow the inverse behavior of main-sequence stars, enabling a more
    accurate characterization of the disrupted star.
acknowledgement: "This work was performed in part at Aspen Center for Physics, which
  is supported by National Science Foundation grant PHY-2210452. We thank the participants
  and organizers of the summer Aspen 2023 workshop on “Stellar Interactions and the
  Transients They Cause” for fruitful discussions. B.M. is grateful for support from
  the Carnegie Theoretical Astrophysics\r\nCenter. M.G.-G. is grateful for the support
  from Northwestern University’s Presidential Fellowship. E.R.-R. thanks the Heising-Simons
  Foundation, NSF (AST-2150255 and AST2307710), Swift (80NSSC21K1409, 80NSSC19K1391),
  and Chandra (22-0142) for support. "
article_number: L9
article_processing_charge: Yes
article_type: original
author:
- first_name: Brenna
  full_name: Mockler, Brenna
  last_name: Mockler
- first_name: Monica
  full_name: Gallegos-Garcia, Monica
  last_name: Gallegos-Garcia
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: Jon M.
  full_name: Miller, Jon M.
  last_name: Miller
- first_name: Enrico
  full_name: Ramirez-Ruiz, Enrico
  last_name: Ramirez-Ruiz
citation:
  ama: Mockler B, Gallegos-Garcia M, Götberg YLL, Miller JM, Ramirez-Ruiz E. Tidal
    disruption events from stripped stars. <i>Astrophysical Journal Letters</i>. 2024;973(1).
    doi:<a href="https://doi.org/10.3847/2041-8213/ad6c34">10.3847/2041-8213/ad6c34</a>
  apa: Mockler, B., Gallegos-Garcia, M., Götberg, Y. L. L., Miller, J. M., &#38; Ramirez-Ruiz,
    E. (2024). Tidal disruption events from stripped stars. <i>Astrophysical Journal
    Letters</i>. IOP Publishing. <a href="https://doi.org/10.3847/2041-8213/ad6c34">https://doi.org/10.3847/2041-8213/ad6c34</a>
  chicago: Mockler, Brenna, Monica Gallegos-Garcia, Ylva Louise Linsdotter Götberg,
    Jon M. Miller, and Enrico Ramirez-Ruiz. “Tidal Disruption Events from Stripped
    Stars.” <i>Astrophysical Journal Letters</i>. IOP Publishing, 2024. <a href="https://doi.org/10.3847/2041-8213/ad6c34">https://doi.org/10.3847/2041-8213/ad6c34</a>.
  ieee: B. Mockler, M. Gallegos-Garcia, Y. L. L. Götberg, J. M. Miller, and E. Ramirez-Ruiz,
    “Tidal disruption events from stripped stars,” <i>Astrophysical Journal Letters</i>,
    vol. 973, no. 1. IOP Publishing, 2024.
  ista: Mockler B, Gallegos-Garcia M, Götberg YLL, Miller JM, Ramirez-Ruiz E. 2024.
    Tidal disruption events from stripped stars. Astrophysical Journal Letters. 973(1),
    L9.
  mla: Mockler, Brenna, et al. “Tidal Disruption Events from Stripped Stars.” <i>Astrophysical
    Journal Letters</i>, vol. 973, no. 1, L9, IOP Publishing, 2024, doi:<a href="https://doi.org/10.3847/2041-8213/ad6c34">10.3847/2041-8213/ad6c34</a>.
  short: B. Mockler, M. Gallegos-Garcia, Y.L.L. Götberg, J.M. Miller, E. Ramirez-Ruiz,
    Astrophysical Journal Letters 973 (2024).
date_created: 2024-09-22T22:01:42Z
date_published: 2024-09-12T00:00:00Z
date_updated: 2025-09-08T09:48:50Z
day: '12'
ddc:
- '520'
department:
- _id: YlGo
doi: 10.3847/2041-8213/ad6c34
external_id:
  isi:
  - '001310592900001'
file:
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  creator: dernst
  date_created: 2024-09-30T08:54:26Z
  date_updated: 2024-09-30T08:54:26Z
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  file_size: 844227
  relation: main_file
  success: 1
file_date_updated: 2024-09-30T08:54:26Z
has_accepted_license: '1'
intvolume: '       973'
isi: 1
issue: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Astrophysical Journal Letters
publication_identifier:
  eissn:
  - 2041-8213
  issn:
  - 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tidal disruption events from stripped stars
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 973
year: '2024'
...
---
_id: '18113'
abstract:
- lang: eng
  text: 'The emergence of accurate open large language models (LLMs) has led to a
    race towards performant quantization techniques which can enable their execution
    on end-user devices. In this paper, we revisit the problem of “extreme” LLM compression—defined
    as targeting extremely low bit counts, such as 2 to 3 bits per parameter—from
    the point of view of classic methods in Multi-Codebook Quantization (MCQ). Our
    algorithm, called AQLM, generalizes the classic Additive Quantization (AQ) approach
    for information retrieval to advance the state-of-the-art in LLM compression,
    via two innovations: 1) learned additive quantization of weight matrices in input-adaptive
    fashion, and 2) joint optimization of codebook parameters across each transformer
    blocks. Broadly, AQLM is the first scheme that is Pareto optimal in terms of accuracy-vs-model-size
    when compressing to less than 3 bits per parameter, and significantly improves
    upon all known schemes in the extreme compression (2bit) regime. In addition,
    AQLM is practical: we provide fast GPU and CPU implementations of AQLM for token
    generation, which enable us to match or outperform optimized FP16 implementations
    for speed, while executing in a much smaller memory footprint.'
acknowledgement: "Authors would like to thank Ruslan Svirschevski for his help in
  solving technical issues with AQLM and baselines. We also thank Tim Dettmers for
  helpful discussions on the structure of weights in modern LLMs and size-accuracy
  trade-offs. The authors would also like to thank Daniil Pavlov for his assistance
  with CPU benchmarking. Finally, authors would like to thank the communities of ML
  enthusiasts known as LocalLLaMA5 and Petals community on discord6\r\nfor the crowd
  wisdom about running LLMs on consumer devices. Egiazarian Vage and Denis Kuznedelev
  and Andrei Panferov were supported by the grant for research centers in the field
  of AI provided by the Analytical Center for the Government of the Russian Federation
  (ACRF) in\r\naccordance with the agreement on the provision of subsidies (identifier
  of the agreement 000000D730321P5Q0002) and the agreement with HSE University No.
  70-2021-00139."
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Vage
  full_name: Egiazarian, Vage
  last_name: Egiazarian
- first_name: Andrei
  full_name: Panferov, Andrei
  id: 2c18daae-4dbe-11ef-8491-98ce2d960f09
  last_name: Panferov
- first_name: Denis
  full_name: Kuznedelev, Denis
  last_name: Kuznedelev
- first_name: Elias
  full_name: Frantar, Elias
  id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f
  last_name: Frantar
- first_name: Artem
  full_name: Babenko, Artem
  last_name: Babenko
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Egiazarian V, Panferov A, Kuznedelev D, Frantar E, Babenko A, Alistarh D-A.
    Extreme compression of large language models via additive quantization. In: <i>Proceedings
    of the 41st International Conference on Machine Learning</i>. Vol 235. ML Research
    Press; 2024:12284-12303.'
  apa: 'Egiazarian, V., Panferov, A., Kuznedelev, D., Frantar, E., Babenko, A., &#38;
    Alistarh, D.-A. (2024). Extreme compression of large language models via additive
    quantization. In <i>Proceedings of the 41st International Conference on Machine
    Learning</i> (Vol. 235, pp. 12284–12303). Vienna, Austria: ML Research Press.'
  chicago: Egiazarian, Vage, Andrei Panferov, Denis Kuznedelev, Elias Frantar, Artem
    Babenko, and Dan-Adrian Alistarh. “Extreme Compression of Large Language Models
    via Additive Quantization.” In <i>Proceedings of the 41st International Conference
    on Machine Learning</i>, 235:12284–303. ML Research Press, 2024.
  ieee: V. Egiazarian, A. Panferov, D. Kuznedelev, E. Frantar, A. Babenko, and D.-A.
    Alistarh, “Extreme compression of large language models via additive quantization,”
    in <i>Proceedings of the 41st International Conference on Machine Learning</i>,
    Vienna, Austria, 2024, vol. 235, pp. 12284–12303.
  ista: 'Egiazarian V, Panferov A, Kuznedelev D, Frantar E, Babenko A, Alistarh D-A.
    2024. Extreme compression of large language models via additive quantization.
    Proceedings of the 41st International Conference on Machine Learning. ICML: International
    Conference on Machine Learning, PMLR, vol. 235, 12284–12303.'
  mla: Egiazarian, Vage, et al. “Extreme Compression of Large Language Models via
    Additive Quantization.” <i>Proceedings of the 41st International Conference on
    Machine Learning</i>, vol. 235, ML Research Press, 2024, pp. 12284–303.
  short: V. Egiazarian, A. Panferov, D. Kuznedelev, E. Frantar, A. Babenko, D.-A.
    Alistarh, in:, Proceedings of the 41st International Conference on Machine Learning,
    ML Research Press, 2024, pp. 12284–12303.
conference:
  end_date: 2024-07-27
  location: Vienna, Austria
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2024-07-21
corr_author: '1'
date_created: 2024-09-22T22:01:43Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2024-10-01T08:13:05Z
day: '01'
department:
- _id: DaAl
- _id: GradSch
external_id:
  arxiv:
  - '2401.06118'
intvolume: '       235'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2401.06118'
month: '09'
oa: 1
oa_version: Preprint
page: 12284-12303
publication: Proceedings of the 41st International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extreme compression of large language models via additive quantization
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 235
year: '2024'
...
---
OA_place: publisher
OA_type: diamond
_id: '18114'
abstract:
- lang: eng
  text: This paper presents Mechanistic Neural Networks, a neural network design for
    machine learning applications in the sciences. It incorporates a new Mechanistic
    Block in standard architectures to explicitly learn governing differential equations
    as representations, revealing the underlying dynamics of data and enhancing interpretability
    and efficiency in data modeling. Central to our approach is a novel Relaxed Linear
    Programming Solver (NeuRLP) inspired by a technique that reduces solving linear
    ODEs to solving linear programs. This integrates well with neural networks and
    surpasses the limitations of traditional ODE solvers enabling scalable GPU parallel
    processing. Overall, Mechanistic Neural Networks demonstrate their versatility
    for scientific machine learning applications, adeptly managing tasks from equation
    discovery to dynamic systems modeling. We prove their comprehensive capabilities
    in analyzing and interpreting complex scientific data across various applications,
    showing significant performance against specialized state-of-the-art methods.
    Source code is available at https://github.com/alpz/mech-nn.
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Adeel A
  full_name: Pervez, Adeel A
  id: fca6d90c-d47f-11ee-bc87-93ff51604981
  last_name: Pervez
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Efstratios
  full_name: Gavves, Efstratios
  last_name: Gavves
citation:
  ama: 'Pervez AA, Locatello F, Gavves E. Mechanistic neural networks for scientific
    machine learning. In: <i>Proceedings of the 41st International Conference on Machine
    Learning</i>. Vol 235. ML Research Press; 2024:40484-40501.'
  apa: 'Pervez, A. A., Locatello, F., &#38; Gavves, E. (2024). Mechanistic neural
    networks for scientific machine learning. In <i>Proceedings of the 41st International
    Conference on Machine Learning</i> (Vol. 235, pp. 40484–40501). Vienna, Austria:
    ML Research Press.'
  chicago: Pervez, Adeel A, Francesco Locatello, and Efstratios Gavves. “Mechanistic
    Neural Networks for Scientific Machine Learning.” In <i>Proceedings of the 41st
    International Conference on Machine Learning</i>, 235:40484–501. ML Research Press,
    2024.
  ieee: A. A. Pervez, F. Locatello, and E. Gavves, “Mechanistic neural networks for
    scientific machine learning,” in <i>Proceedings of the 41st International Conference
    on Machine Learning</i>, Vienna, Austria, 2024, vol. 235, pp. 40484–40501.
  ista: 'Pervez AA, Locatello F, Gavves E. 2024. Mechanistic neural networks for scientific
    machine learning. Proceedings of the 41st International Conference on Machine
    Learning. ICML: International Conference on Machine Learning, PMLR, vol. 235,
    40484–40501.'
  mla: Pervez, Adeel A., et al. “Mechanistic Neural Networks for Scientific Machine
    Learning.” <i>Proceedings of the 41st International Conference on Machine Learning</i>,
    vol. 235, ML Research Press, 2024, pp. 40484–501.
  short: A.A. Pervez, F. Locatello, E. Gavves, in:, Proceedings of the 41st International
    Conference on Machine Learning, ML Research Press, 2024, pp. 40484–40501.
conference:
  end_date: 2024-07-27
  location: Vienna, Austria
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2024-07-21
date_created: 2024-09-22T22:01:43Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2026-06-18T17:59:46Z
day: '01'
ddc:
- '000'
department:
- _id: FrLo
external_id:
  arxiv:
  - '2402.13077'
intvolume: '       235'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2402.13077
month: '09'
oa: 1
oa_version: Published Version
page: 40484-40501
publication: Proceedings of the 41st International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/alpz/mech-nn
scopus_import: '1'
status: public
title: Mechanistic neural networks for scientific machine learning
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 235
year: '2024'
...
