---
OA_place: repository
OA_type: green
_id: '17426'
abstract:
- lang: eng
  text: "The robustness of neural networks against input perturbations with bounded\r\nmagnitude
    represents a serious concern in the deployment of deep learning\r\nmodels in safety-critical
    systems. Recently, the scientific community has\r\nfocused on enhancing certifiable
    robustness guarantees by crafting 1-Lipschitz\r\nneural networks that leverage
    Lipschitz bounded dense and convolutional layers.\r\nAlthough different methods
    have been proposed in the literature to achieve this\r\ngoal, understanding the
    performance of such methods is not straightforward,\r\nsince different metrics
    can be relevant (e.g., training time, memory usage,\r\naccuracy, certifiable robustness)
    for different applications. For this reason,\r\nthis work provides a thorough
    theoretical and empirical comparison between\r\nmethods by evaluating them in
    terms of memory usage, speed, and certifiable\r\nrobust accuracy. The paper also
    provides some guidelines and recommendations to\r\nsupport the user in selecting
    the methods that work best depending on the\r\navailable resources. We provide
    code at\r\nhttps://github.com/berndprach/1LipschitzLayersCompared."
acknowledgement: "This work was partially supported by project SERICS (PE00000014)
  under the MUR National Recovery and Resilience Plan funded by the European Union
  - NextGenerationEU.\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Bernd
  full_name: Prach, Bernd
  id: 2D561D42-C427-11E9-89B4-9C1AE6697425
  last_name: Prach
- first_name: Fabio
  full_name: Brau, Fabio
  last_name: Brau
- first_name: Giorgio
  full_name: Buttazzo, Giorgio
  last_name: Buttazzo
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Prach B, Brau F, Buttazzo G, Lampert C. 1-Lipschitz layers compared: Memory,
    speed, and certifiable robustness. In: <i>Proceedings of the IEEE/CVF Conference
    on Computer Vision and Pattern Recognition</i>. Computer Vision Foundation; 2024:24574-24583.
    doi:<a href="https://doi.org/10.1109/CVPR52733.2024.02320">10.1109/CVPR52733.2024.02320</a>'
  apa: 'Prach, B., Brau, F., Buttazzo, G., &#38; Lampert, C. (2024). 1-Lipschitz layers
    compared: Memory, speed, and certifiable robustness. In <i>Proceedings of the
    IEEE/CVF Conference on Computer Vision and Pattern Recognition</i> (pp. 24574–24583).
    Seattle, WA, United States: Computer Vision Foundation. <a href="https://doi.org/10.1109/CVPR52733.2024.02320">https://doi.org/10.1109/CVPR52733.2024.02320</a>'
  chicago: 'Prach, Bernd, Fabio Brau, Giorgio Buttazzo, and Christoph Lampert. “1-Lipschitz
    Layers Compared: Memory, Speed, and Certifiable Robustness.” In <i>Proceedings
    of the IEEE/CVF Conference on Computer Vision and Pattern Recognition</i>, 24574–83.
    Computer Vision Foundation, 2024. <a href="https://doi.org/10.1109/CVPR52733.2024.02320">https://doi.org/10.1109/CVPR52733.2024.02320</a>.'
  ieee: 'B. Prach, F. Brau, G. Buttazzo, and C. Lampert, “1-Lipschitz layers compared:
    Memory, speed, and certifiable robustness,” in <i>Proceedings of the IEEE/CVF
    Conference on Computer Vision and Pattern Recognition</i>, Seattle, WA, United
    States, 2024, pp. 24574–24583.'
  ista: 'Prach B, Brau F, Buttazzo G, Lampert C. 2024. 1-Lipschitz layers compared:
    Memory, speed, and certifiable robustness. Proceedings of the IEEE/CVF Conference
    on Computer Vision and Pattern Recognition. CVPR: Conference on Computer Vision
    and Pattern Recognition, 24574–24583.'
  mla: 'Prach, Bernd, et al. “1-Lipschitz Layers Compared: Memory, Speed, and Certifiable
    Robustness.” <i>Proceedings of the IEEE/CVF Conference on Computer Vision and
    Pattern Recognition</i>, Computer Vision Foundation, 2024, pp. 24574–83, doi:<a
    href="https://doi.org/10.1109/CVPR52733.2024.02320">10.1109/CVPR52733.2024.02320</a>.'
  short: B. Prach, F. Brau, G. Buttazzo, C. Lampert, in:, Proceedings of the IEEE/CVF
    Conference on Computer Vision and Pattern Recognition, Computer Vision Foundation,
    2024, pp. 24574–24583.
conference:
  end_date: 2024-06-22
  location: Seattle, WA, United States
  name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
  start_date: 2024-06-16
corr_author: '1'
das_tickbox: '0'
date_created: 2024-08-14T08:42:32Z
date_published: 2024-06-01T00:00:00Z
date_updated: 2026-10-02T11:16:04Z
day: '01'
department:
- _id: GradSch
- _id: ChLa
doi: 10.1109/CVPR52733.2024.02320
external_id:
  arxiv:
  - '2311.16833'
  isi:
  - '001344387500055'
fulldoi: https://doi.org/10.1109/CVPR52733.2024.02320
has_accepted_license: '1'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2311.16833
month: '06'
oa: 1
oa_version: Preprint
page: 24574-24583
publication: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern
  Recognition
publication_status: published
publisher: Computer Vision Foundation
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/berndprach/1LipschitzLayersCompared
  record:
  - id: '19759'
    relation: dissertation_contains
    status: public
researchdata_availability: no
status: public
supplementarymaterial: no
title: '1-Lipschitz layers compared: Memory, speed, and certifiable robustness'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
OA_place: repository
_id: '18874'
abstract:
- lang: eng
  text: "Despite extensive research since the community learned about adversarial\r\nexamples
    10 years ago, we still do not know how to train high-accuracy\r\nclassifiers that
    are guaranteed to be robust to small perturbations of their\r\ninputs. Previous
    works often argued that this might be because no classifier\r\nexists that is
    robust and accurate at the same time. However, in computer\r\nvision this assumption
    does not match reality where humans are usually accurate\r\nand robust on most
    tasks of interest. We offer an alternative explanation and\r\nshow that in certain
    settings robust generalization is only possible with\r\nunrealistically large
    amounts of data. More precisely we find a setting where a\r\nrobust classifier
    exists, it is easy to learn an accurate classifier, yet it\r\nrequires an exponential
    amount of data to learn a robust classifier. Based on\r\nthis theoretical result,
    we explore how well robust classifiers generalize on\r\ndatasets such as CIFAR-10.
    We come to the conclusion that on this datasets, the\r\nlimitation of current
    robust models also lies in the generalization, and that\r\nthey require a lot
    of data to do well on the test set. We also show that the\r\nproblem is not in
    the expressiveness or generalization capabilities of current\r\narchitectures,
    and that there are low magnitude features in the data which are\r\nuseful for
    non-robust generalization but are not available for robust\r\nclassifiers."
article_number: '2412.04245'
article_processing_charge: No
arxiv: 1
author:
- first_name: Bernd
  full_name: Prach, Bernd
  id: 2D561D42-C427-11E9-89B4-9C1AE6697425
  last_name: Prach
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: Prach B, Lampert C. Intriguing properties of robust classification. <i>arXiv</i>.
    doi:<a href="https://doi.org/10.48550/arXiv.2412.04245">10.48550/arXiv.2412.04245</a>
  apa: Prach, B., &#38; Lampert, C. (n.d.). Intriguing properties of robust classification.
    <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2412.04245">https://doi.org/10.48550/arXiv.2412.04245</a>
  chicago: Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2412.04245">https://doi.org/10.48550/arXiv.2412.04245</a>.
  ieee: B. Prach and C. Lampert, “Intriguing properties of robust classification,”
    <i>arXiv</i>. .
  ista: Prach B, Lampert C. Intriguing properties of robust classification. arXiv,
    2412.04245.
  mla: Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.”
    <i>ArXiv</i>, 2412.04245, doi:<a href="https://doi.org/10.48550/arXiv.2412.04245">10.48550/arXiv.2412.04245</a>.
  short: B. Prach, C. Lampert, ArXiv (n.d.).
corr_author: '1'
das_tickbox: '0'
date_created: 2025-01-24T16:57:29Z
date_published: 2024-12-05T00:00:00Z
date_updated: 2026-10-02T11:15:43Z
day: '05'
department:
- _id: GradSch
- _id: ChLa
doi: 10.48550/arXiv.2412.04245
external_id:
  arxiv:
  - '2412.04245'
fulldoi: https://doi.org/10.48550/arXiv.2412.04245
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2412.04245
month: '12'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
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    relation: later_version
    status: public
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researchdata_availability: no
status: public
supplementarymaterial: yes
title: Intriguing properties of robust classification
type: preprint
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
OA_place: repository
_id: '17361'
abstract:
- lang: eng
  text: We present symplectic structures on the shape space of unparameterized space
    curves that generalize the classical Marsden-Weinstein structure. Our method integrates
    the Liouville 1-form of the Marsden-Weinstein structure with Riemannian structures
    that have been introduced in mathematical shape analysis. We also derive Hamiltonian
    vector fields for several classical Hamiltonian functions with respect to these
    new symplectic structures.
acknowledgement: The authors are grateful to Boris Khesin for valuable comments on
  the MW symplectic structure and S. Ishida thanks Albert Chern for insightful discussions
  on space curves and Chris Wojtan for his continuous support. M. Bauer was partially
  supported by NSF grant DMS-1953244 and by the Binational Science Foundation (BSF).
  S. Ishida was partially supported by ERC Consolidator Grant 101045083 “CoDiNA” funded
  by the European Research Council. Some figures were generated by the software Houdini
  and its education license was provided by SideFX.
article_processing_charge: No
arxiv: 1
author:
- first_name: Martin
  full_name: Bauer, Martin
  last_name: Bauer
- first_name: Sadashige
  full_name: Ishida, Sadashige
  id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
  last_name: Ishida
  orcid: 0000-0002-3121-3100
- first_name: Peter W.
  full_name: Michor, Peter W.
  last_name: Michor
citation:
  ama: Bauer M, Ishida S, Michor PW. Symplectic structures on the space of space curves.
    <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2407.19908">10.48550/arXiv.2407.19908</a>
  apa: Bauer, M., Ishida, S., &#38; Michor, P. W. (n.d.). Symplectic structures on
    the space of space curves. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2407.19908">https://doi.org/10.48550/arXiv.2407.19908</a>
  chicago: Bauer, Martin, Sadashige Ishida, and Peter W. Michor. “Symplectic Structures
    on the Space of Space Curves.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2407.19908">https://doi.org/10.48550/arXiv.2407.19908</a>.
  ieee: M. Bauer, S. Ishida, and P. W. Michor, “Symplectic structures on the space
    of space curves,” <i>arXiv</i>. .
  ista: Bauer M, Ishida S, Michor PW. Symplectic structures on the space of space
    curves. arXiv, <a href="https://doi.org/10.48550/arXiv.2407.19908">10.48550/arXiv.2407.19908</a>.
  mla: Bauer, Martin, et al. “Symplectic Structures on the Space of Space Curves.”
    <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/arXiv.2407.19908">10.48550/arXiv.2407.19908</a>.
  short: M. Bauer, S. Ishida, P.W. Michor, ArXiv (n.d.).
das_tickbox: '0'
date_created: 2024-08-01T06:34:08Z
date_published: 2024-07-29T00:00:00Z
date_updated: 2026-10-02T11:16:46Z
day: '29'
department:
- _id: GradSch
- _id: ChWo
doi: 10.48550/arXiv.2407.19908
external_id:
  arxiv:
  - '2407.19908'
fulldoi: https://doi.org/10.48550/arXiv.2407.19908
keyword:
- space of space curves
- symplectic stuctures
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2407.19908
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: arXiv
publication_status: draft
related_material:
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  - id: '20551'
    relation: dissertation_contains
    status: public
  - id: '21743'
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    status: public
researchdata_availability: no
status: public
supplementarymaterial: no
title: Symplectic structures on the space of space curves
type: preprint
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '17219'
abstract:
- lang: eng
  text: 'We introduce a multi-material non-manifold mesh-based surface tracking algorithm
    that converts self-intersections into topological changes. Our algorithm generalizes
    prior work on manifold surface tracking with topological changes: it preserves
    surface features like mesh-based methods, and it robustly handles topological
    changes like level set methods. Our method also offers improved efficiency and
    robustness over the state of the art. We demonstrate the effectiveness of the
    approach on a range of examples, including complex soap film simulations with
    thousands of interacting bubbles, and boolean unions of non-manifold meshes consisting
    of millions of triangles.'
acknowledgement: Peter Heiss-Synak helped conceive the project, helped formulate the
  algorithm structure, contributed ideas and code to Sections 6 & 8, the mesh data
  structure, algorithm robustness and benchmarks, helped write the paper, and provided
  supervision and conceptual solutions throughout the project. Aleksei Kalinov contributed
  ideas and code to Sections 7, 8.5, and 5, the sparse grid data structure, algorithm
  robustness and benchmarks, optimized the performance, produced all results, most
  figures, and the supplementary video, helped write the text, and provided conceptual
  solutions throughout the project. Malina Strugaru helped implement the mesh data
  structure and designed re-meshing operations for non-manifold triangle meshes. Arian
  Etemadi developed early prototypes for ideas in Sections 8.1 and 8.3 and helped
  write the paper. Huidong Yang developed early prototypes for isosurface extraction
  and visualization. Chris Wojtan helped conceive the project, helped write the paper,
  and provided supervision, prototype grid data structure code, and conceptual solutions
  throughout the project. We thank the anonymous reviewers for their helpful comments,
  the members of the Visual Computing Group at ISTA for their feedback, Christopher
  Batty for discussions about LosTopos, and SideFX for the Houdini Education software
  licenses.  This research was funded in part by the European Union (ERC-2021-COG
  101045083 CoDiNA).
article_number: '54'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Peter
  full_name: Synak, Peter
  id: 331776E2-F248-11E8-B48F-1D18A9856A87
  last_name: Synak
- first_name: Aleksei
  full_name: Kalinov, Aleksei
  id: 44b7120e-eb97-11eb-a6c2-e1557aa81d02
  last_name: Kalinov
  orcid: 0000-0003-2189-3904
- first_name: Irina-Malina
  full_name: Strugaru, Irina-Malina
  id: 2afc607f-f128-11eb-9611-8f2a0dfcf074
  last_name: Strugaru
- first_name: Arian
  full_name: Etemadihaghighi, Arian
  id: 36cea3aa-f38e-11ec-8ae0-c65ae6f6098f
  last_name: Etemadihaghighi
- first_name: Huidong
  full_name: Yang, Huidong
  last_name: Yang
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Synak P, Kalinov A, Strugaru I-M, Etemadi A, Yang H, Wojtan C. Multi-material
    mesh-based surface tracking with implicit topology changes. <i>ACM Transactions
    on Graphics</i>. 2024;43(4). doi:<a href="https://doi.org/10.1145/3658223">10.1145/3658223</a>
  apa: Synak, P., Kalinov, A., Strugaru, I.-M., Etemadi, A., Yang, H., &#38; Wojtan,
    C. (2024). Multi-material mesh-based surface tracking with implicit topology changes.
    <i>ACM Transactions on Graphics</i>. Association for Computing Machinery. <a href="https://doi.org/10.1145/3658223">https://doi.org/10.1145/3658223</a>
  chicago: Synak, Peter, Aleksei Kalinov, Irina-Malina Strugaru, Arian Etemadi, Huidong
    Yang, and Chris Wojtan. “Multi-Material Mesh-Based Surface Tracking with Implicit
    Topology Changes.” <i>ACM Transactions on Graphics</i>. Association for Computing
    Machinery, 2024. <a href="https://doi.org/10.1145/3658223">https://doi.org/10.1145/3658223</a>.
  ieee: P. Synak, A. Kalinov, I.-M. Strugaru, A. Etemadi, H. Yang, and C. Wojtan,
    “Multi-material mesh-based surface tracking with implicit topology changes,” <i>ACM
    Transactions on Graphics</i>, vol. 43, no. 4. Association for Computing Machinery,
    2024.
  ista: Synak P, Kalinov A, Strugaru I-M, Etemadi A, Yang H, Wojtan C. 2024. Multi-material
    mesh-based surface tracking with implicit topology changes. ACM Transactions on
    Graphics. 43(4), 54.
  mla: Synak, Peter, et al. “Multi-Material Mesh-Based Surface Tracking with Implicit
    Topology Changes.” <i>ACM Transactions on Graphics</i>, vol. 43, no. 4, 54, Association
    for Computing Machinery, 2024, doi:<a href="https://doi.org/10.1145/3658223">10.1145/3658223</a>.
  short: P. Synak, A. Kalinov, I.-M. Strugaru, A. Etemadi, H. Yang, C. Wojtan, ACM
    Transactions on Graphics 43 (2024).
corr_author: '1'
das_tickbox: '0'
date_created: 2024-07-10T12:24:00Z
date_published: 2024-07-01T00:00:00Z
date_updated: 2026-10-02T11:19:25Z
day: '01'
ddc:
- '004'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1145/3658223
external_id:
  isi:
  - '001289270900021'
file:
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  checksum: 1917067d4b52d7729019b03560004e43
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-23T06:35:15Z
  date_updated: 2024-07-23T06:35:15Z
  file_id: '17317'
  file_name: 2024_ACMToG_HeissSynak.pdf
  file_size: 48763368
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  checksum: a4f0e293184bfa034c0c585848806b17
  content_type: video/mp4
  creator: akalinov
  date_created: 2024-07-10T12:23:44Z
  date_updated: 2024-07-10T12:23:44Z
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  date_updated: 2025-11-11T09:50:52Z
  file_id: '20633'
  file_name: SuperDuperTopoFixer.pdf
  file_size: 48639581
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  title: Authors' version of the text
file_date_updated: 2025-11-11T09:50:52Z
fulldoi: https://doi.org/10.1145/3658223
has_accepted_license: '1'
intvolume: '        43'
isi: 1
issue: '4'
keyword:
- surface tracking
- topology change
- non- manifold meshes
- multi-material flows
- solid modeling
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: ACM Transactions on Graphics
publication_identifier:
  eissn:
  - 1557-7368
  issn:
  - 0730-0301
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
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supplementarymaterial: no
title: Multi-material mesh-based surface tracking with implicit topology changes
tmp:
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  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
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...
---
OA_place: publisher
_id: '18301'
abstract:
- lang: eng
  text: Physics simulation in computer graphics can bring triangle meshes into topologically
    invalid states. The method in this thesis contributed to Heiss-Synak* and Kalinov*
    et al. [2024] who devised a non-manifold hybrid surface tracker—a surface tracker
    that repairs explicit non-manifold triangle meshes with the help of the implicit
    domain. Specifically, this thesis provides an algorithm for filling the holes
    that are left after removing problematic parts of the mesh.
alternative_title:
- ISTA Master's Thesis
article_processing_charge: No
author:
- first_name: Arian
  full_name: Etemadihaghighi, Arian
  id: 36cea3aa-f38e-11ec-8ae0-c65ae6f6098f
  last_name: Etemadihaghighi
citation:
  ama: Etemadi A. Filling the holes of non-manifold self-intersecting meshes for implicit
    topology changes in surface tracking. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18301">10.15479/at:ista:18301</a>
  apa: Etemadi, A. (2024). <i>Filling the holes of non-manifold self-intersecting
    meshes for implicit topology changes in surface tracking</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18301">https://doi.org/10.15479/at:ista:18301</a>
  chicago: Etemadi, Arian. “Filling the Holes of Non-Manifold Self-Intersecting Meshes
    for Implicit Topology Changes in Surface Tracking.” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18301">https://doi.org/10.15479/at:ista:18301</a>.
  ieee: A. Etemadi, “Filling the holes of non-manifold self-intersecting meshes for
    implicit topology changes in surface tracking,” Institute of Science and Technology
    Austria, 2024.
  ista: Etemadi A. 2024. Filling the holes of non-manifold self-intersecting meshes
    for implicit topology changes in surface tracking. Institute of Science and Technology
    Austria.
  mla: Etemadi, Arian. <i>Filling the Holes of Non-Manifold Self-Intersecting Meshes
    for Implicit Topology Changes in Surface Tracking</i>. Institute of Science and
    Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18301">10.15479/at:ista:18301</a>.
  short: A. Etemadi, Filling the Holes of Non-Manifold Self-Intersecting Meshes for
    Implicit Topology Changes in Surface Tracking, Institute of Science and Technology
    Austria, 2024.
corr_author: '1'
das_tickbox: '0'
date_created: 2024-10-11T19:52:20Z
date_published: 2024-10-15T00:00:00Z
date_updated: 2026-10-02T11:19:26Z
day: '15'
ddc:
- '000'
degree_awarded: MS
department:
- _id: GradSch
- _id: ChWo
doi: 10.15479/at:ista:18301
doi_confirm: '1'
file:
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fulldoi: https://doi.org/10.15479/at:ista:18301
has_accepted_license: '1'
keyword:
- surface tracking
- non-manifold
- hole-filling
- topology change
- multi-material
- solid-modeling
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: '39'
publication_identifier:
  issn:
  - 2791-4585
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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  - id: '17219'
    relation: part_of_dissertation
    status: public
researchdata_availability: no
status: public
supervisor:
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
supplementarymaterial: no
title: Filling the holes of non-manifold self-intersecting meshes for implicit topology
  changes in surface tracking
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
  name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: dissertation
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '12846'
abstract:
- lang: eng
  text: We present a formula for the signed area of a spherical polygon via prequantization.
    In contrast to the traditional formula based on the Gauss-Bonnet theorem that
    requires measuring angles, the new formula mimics Green's theorem and is applicable
    to a wider range of degenerate spherical curves and polygons.
acknowledgement: This work was funded by European Research Council Consolidator grant
  101045083 CoDiNA and National Science Foundation CAREER award 2239062. Some figures
  in the article were generated by the software Houdini and its education license
  was provided by SideFX. The authors acknowledge anonymous referees for their reviews
  and insightful suggestions, and Chris Wojtan for his continuous support through
  discussions. The second author thanks Anna Sisak for a fruitful discussion on prequantum
  bundles.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Albert
  full_name: Chern, Albert
  last_name: Chern
- first_name: Sadashige
  full_name: Ishida, Sadashige
  id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
  last_name: Ishida
  orcid: 0000-0002-3121-3100
citation:
  ama: Chern A, Ishida S. Area formula for spherical polygons via prequantization.
    <i>SIAM Journal on Applied Algebra and Geometry</i>. 2024;8(3):782-796. doi:<a
    href="https://doi.org/10.1137/23M1565255">10.1137/23M1565255</a>
  apa: Chern, A., &#38; Ishida, S. (2024). Area formula for spherical polygons via
    prequantization. <i>SIAM Journal on Applied Algebra and Geometry</i>. Society
    for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/23M1565255">https://doi.org/10.1137/23M1565255</a>
  chicago: Chern, Albert, and Sadashige Ishida. “Area Formula for Spherical Polygons
    via Prequantization.” <i>SIAM Journal on Applied Algebra and Geometry</i>. Society
    for Industrial and Applied Mathematics, 2024. <a href="https://doi.org/10.1137/23M1565255">https://doi.org/10.1137/23M1565255</a>.
  ieee: A. Chern and S. Ishida, “Area formula for spherical polygons via prequantization,”
    <i>SIAM Journal on Applied Algebra and Geometry</i>, vol. 8, no. 3. Society for
    Industrial and Applied Mathematics, pp. 782–796, 2024.
  ista: Chern A, Ishida S. 2024. Area formula for spherical polygons via prequantization.
    SIAM Journal on Applied Algebra and Geometry. 8(3), 782–796.
  mla: Chern, Albert, and Sadashige Ishida. “Area Formula for Spherical Polygons via
    Prequantization.” <i>SIAM Journal on Applied Algebra and Geometry</i>, vol. 8,
    no. 3, Society for Industrial and Applied Mathematics, 2024, pp. 782–96, doi:<a
    href="https://doi.org/10.1137/23M1565255">10.1137/23M1565255</a>.
  short: A. Chern, S. Ishida, SIAM Journal on Applied Algebra and Geometry 8 (2024)
    782–796.
corr_author: '1'
das_tickbox: '0'
date_created: 2023-04-18T19:16:06Z
date_published: 2024-09-23T00:00:00Z
date_updated: 2026-10-02T11:17:04Z
day: '23'
ddc:
- '516'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1137/23M1565255
external_id:
  arxiv:
  - '2303.14555'
  isi:
  - '001342265800009'
fulldoi: https://doi.org/10.1137/23M1565255
has_accepted_license: '1'
intvolume: '         8'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2303.14555
month: '09'
oa: 1
oa_version: Preprint
page: 782-796
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: SIAM Journal on Applied Algebra and Geometry
publication_identifier:
  eissn:
  - 2470-6566
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
  record:
  - id: '20551'
    relation: dissertation_contains
    status: public
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Area formula for spherical polygons via prequantization
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2024'
...
---
OA_place: publisher
_id: '17485'
abstract:
- lang: eng
  text: "Large language models (LLMs) have made tremendous progress in the past few
    years, from being able to generate coherent text to matching or surpassing humans
    in a wide variety of creative, knowledge or reasoning tasks. Much of this can
    be attributed to massively increased scale, both in the size of the model as well
    as the amount of training data, from 100s of millions to 100s of billions, or
    even trillions. This trend is expected to continue, which, although exciting,
    also raises major practical concerns. Already today's 100+ billion parameter LLMs
    require top-of-the-line hardware just to run. Hence, it is clear that sustaining
    these developments will require significant efficiency advances.\r\n\r\nHistorically,
    one of the most practical ways of improving model efficiency has been compression,
    especially in the form of sparsity or quantization. While this has been studied
    extensively in the past, existing accurate methods are all designed for models
    around 100 million parameters; scaling them up to ones literally 1000x larger
    is highly challenging. In this thesis, we introduce a new unified sparsification
    and quantization approach OBC, which through additional algorithmic enhancements
    leads to GPTQ and SparseGPT, the first techniques fast and accurate enough to
    compress 100+ billion parameter models to 4- or even 3-bit precision and 50% weight-sparsity,
    respectively. Additionally, we show how weight-only quantizion does not just bring
    space savings but also up to 4.5x faster generation speed, via custom GPU kernels.\r\n\r\nIn
    fact, we show for the first time that it is possible to develop an FP16 times
    INT4 mixed-precision matrix multiplication kernel, called Marlin, which comes
    close to simultaneously maximizing both memory and compute utilization, making
    weight-only quantization highly practical even for multi-user serving. Further,
    we demonstrate that GPTQ can be scaled to widely overparametrized trillion-parameter
    models, where extreme sub-1-bit compression rates can be achieved without any
    inference slow-down, by co-designing a bespoke entropy coding scheme together
    with an efficient kernel.\r\n\r\nFinally, we also study compression from the perspective
    of someone with access to massive amounts of compute resources for training large
    models completely from scratch. Here the key questions evolve around the joint
    scaling behavior between compression, model size, and amount of training data
    used. Based on extensive experimental results for both vision and text models,
    we introduce the first scaling law which accurately captures the relationship
    between weight-sparsity, number of non-zero weights and data. This further allows
    us to characterize the optimal sparsity, which we find to increase the longer
    a fixed cost model is being trained.\r\n\r\nOverall, this thesis presents contributions
    to three different angles of large model efficiency: affordable but accurate algorithms,
    highly efficient systems implementations, and fundamental scaling laws for compressed
    training."
acknowledged_ssus:
- _id: ScienComp
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Elias
  full_name: Frantar, Elias
  id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f
  last_name: Frantar
citation:
  ama: 'Frantar E. Compressing large neural networks: Algorithms, systems and scaling
    laws. 2024. doi:<a href="https://doi.org/10.15479/at:ista:17485">10.15479/at:ista:17485</a>'
  apa: 'Frantar, E. (2024). <i>Compressing large neural networks: Algorithms, systems
    and scaling laws</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:17485">https://doi.org/10.15479/at:ista:17485</a>'
  chicago: 'Frantar, Elias. “Compressing Large Neural Networks: Algorithms, Systems
    and Scaling Laws.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:17485">https://doi.org/10.15479/at:ista:17485</a>.'
  ieee: 'E. Frantar, “Compressing large neural networks: Algorithms, systems and scaling
    laws,” Institute of Science and Technology Austria, 2024.'
  ista: 'Frantar E. 2024. Compressing large neural networks: Algorithms, systems and
    scaling laws. Institute of Science and Technology Austria.'
  mla: 'Frantar, Elias. <i>Compressing Large Neural Networks: Algorithms, Systems
    and Scaling Laws</i>. Institute of Science and Technology Austria, 2024, doi:<a
    href="https://doi.org/10.15479/at:ista:17485">10.15479/at:ista:17485</a>.'
  short: 'E. Frantar, Compressing Large Neural Networks: Algorithms, Systems and Scaling
    Laws, Institute of Science and Technology Austria, 2024.'
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-02T11:01:48Z
date_published: 2024-09-05T00:00:00Z
date_updated: 2026-10-02T11:19:46Z
day: '05'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: DaAl
doi: 10.15479/at:ista:17485
doi_confirm: '1'
ec_funded: 1
file:
- access_level: closed
  checksum: 5d785645805a78c5b4ce7cc3df557b09
  content_type: application/zip
  creator: efrantar
  date_created: 2024-09-05T12:04:11Z
  date_updated: 2024-09-05T12:04:11Z
  file_id: '17570'
  file_name: thesis-final.zip
  file_size: 1615167
  relation: source_file
- access_level: open_access
  checksum: a9dd1c2d23734986924eb44ebb55fd8f
  content_type: application/pdf
  creator: efrantar
  date_created: 2024-09-06T16:24:59Z
  date_updated: 2024-09-06T16:24:59Z
  file_id: '17880'
  file_name: frantar_thesis_final.pdf
  file_size: 2376611
  relation: main_file
  success: 1
file_date_updated: 2024-09-06T16:24:59Z
fulldoi: https://doi.org/10.15479/at:ista:17485
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '129'
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '805223'
  name: Elastic Coordination for Scalable Machine Learning
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17378'
    relation: part_of_dissertation
    status: public
  - id: '17087'
    relation: part_of_dissertation
    status: public
  - id: '14458'
    relation: part_of_dissertation
    status: public
  - id: '18061'
    relation: part_of_dissertation
    status: public
  - id: '18062'
    relation: part_of_dissertation
    status: public
researchdata_availability: no
status: public
supervisor:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
supplementarymaterial: no
title: 'Compressing large neural networks: Algorithms, systems and scaling laws'
type: dissertation
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '18062'
abstract:
- lang: eng
  text: 'We explore the impact of parameter sparsity on the scaling behavior of Transformers
    trained on massive datasets (i.e., "foundation models"), in both vision and language
    domains. In this setting, we identify the first scaling law describing the relationship
    between weight sparsity, number of non-zero parameters, and amount of training
    data, which we validate empirically across model and data scales; on ViT/JFT-4B
    and T5/C4. These results allow us to characterize the "optimal sparsity", the
    sparsity level which yields the best performance for a given effective model size
    and training budget. For a fixed number of non-zero parameters, we identify that
    the optimal sparsity increases with the amount of data used for training. We also
    extend our study to different sparsity structures (such as the hardware-friendly
    n:m pattern) and strategies (such as starting from a pretrained dense model).
    Our findings shed light on the power and limitations of weight sparsity across
    various parameter and computational settings, offering both theoretical understanding
    and practical implications for leveraging sparsity towards computational efficiency
    improvements. We provide pruning and scaling law fitting code at: github.com/google-research/jaxpruner/tree/main/jaxpruner/projects/bigsparse.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Elias
  full_name: Frantar, Elias
  id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f
  last_name: Frantar
- first_name: Carlos Riquelme
  full_name: Ruiz, Carlos Riquelme
  last_name: Ruiz
- first_name: Neil
  full_name: Houlsby, Neil
  last_name: Houlsby
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Utku
  full_name: Evci, Utku
  last_name: Evci
citation:
  ama: 'Frantar E, Ruiz CR, Houlsby N, Alistarh D-A, Evci U. Scaling laws for sparsely-connected
    foundation models. In: <i>The Twelfth International Conference on Learning Representations</i>.
    ; 2024.'
  apa: Frantar, E., Ruiz, C. R., Houlsby, N., Alistarh, D.-A., &#38; Evci, U. (2024).
    Scaling laws for sparsely-connected foundation models. In <i>The Twelfth International
    Conference on Learning Representations</i>. Vienna, Austria.
  chicago: Frantar, Elias, Carlos Riquelme Ruiz, Neil Houlsby, Dan-Adrian Alistarh,
    and Utku Evci. “Scaling Laws for Sparsely-Connected Foundation Models.” In <i>The
    Twelfth International Conference on Learning Representations</i>, 2024.
  ieee: E. Frantar, C. R. Ruiz, N. Houlsby, D.-A. Alistarh, and U. Evci, “Scaling
    laws for sparsely-connected foundation models,” in <i>The Twelfth International
    Conference on Learning Representations</i>, Vienna, Austria, 2024.
  ista: 'Frantar E, Ruiz CR, Houlsby N, Alistarh D-A, Evci U. 2024. Scaling laws for
    sparsely-connected foundation models. The Twelfth International Conference on
    Learning Representations. ICLR: International Conference on Learning Representations.'
  mla: Frantar, Elias, et al. “Scaling Laws for Sparsely-Connected Foundation Models.”
    <i>The Twelfth International Conference on Learning Representations</i>, 2024.
  short: E. Frantar, C.R. Ruiz, N. Houlsby, D.-A. Alistarh, U. Evci, in:, The Twelfth
    International Conference on Learning Representations, 2024.
conference:
  end_date: 2024-05-07
  location: Vienna, Austria
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2024-05-07
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-13T10:31:08Z
date_published: 2024-01-16T00:00:00Z
date_updated: 2026-10-02T11:19:46Z
day: '16'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2309.08520'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://openreview.net/forum?id=i9K2ZWkYIP
month: '01'
oa: 1
oa_version: Published Version
publication: The Twelfth International Conference on Learning Representations
publication_status: published
quality_controlled: '1'
related_material:
  record:
  - id: '17485'
    relation: dissertation_contains
    status: public
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Scaling laws for sparsely-connected foundation models
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '18061'
abstract:
- lang: eng
  text: 'Mixture-of-Experts (MoE) architectures offer a general solution to the high
    inference costs of large language models (LLMs) via sparse routing, bringing faster
    and more accurate models, at the cost of massive parameter counts. For example,
    the SwitchTransformer-c2048 model has 1.6 trillion parameters, requiring 3.2TB
    of accelerator memory to run efficiently, which makes practical deployment challenging
    and expensive. In this paper, we present a solution to this memory problem, in
    form of a new compression and execution framework called QMoE. Specifically, QMoE
    consists of a scalable algorithm which accurately compresses trillion-parameter
    MoEs to less than 1 bit per parameter, in a custom format co-designed with bespoke
    GPU decoding kernels to facilitate efficient end-to-end compressed inference,
    with minor runtime overheads relative to uncompressed execution. Concretely, QMoE
    can compress the 1.6 trillion parameter SwitchTransformer-c2048 model to less
    than 160GB (20x compression, 0.8 bits per parameter) at only minor accuracy loss,
    in less than a day on a single GPU. This enables, for the first time, the execution
    of a trillion-parameter model on affordable commodity hardware, like a single
    server with 4x NVIDIA A6000 or 8x NVIDIA 3090 GPUs, at less than 5% runtime overhead
    relative to ideal uncompressed inference. The anonymized code is available at:
    github.com/mlsys24-qmoe/qmoe.'
article_processing_charge: No
author:
- first_name: Elias
  full_name: Frantar, Elias
  id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f
  last_name: Frantar
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Frantar E, Alistarh D-A. QMoE: Sub-1-bit compression of trillion parameter
    models. In: <i>Proceedings of Machine Learning and Systems</i>. Vol 6. ; 2024.'
  apa: 'Frantar, E., &#38; Alistarh, D.-A. (2024). QMoE: Sub-1-bit compression of
    trillion parameter models. In <i>Proceedings of Machine Learning and Systems</i>
    (Vol. 6). Santa Clara, CA, United States.'
  chicago: 'Frantar, Elias, and Dan-Adrian Alistarh. “QMoE: Sub-1-Bit Compression
    of Trillion Parameter Models.” In <i>Proceedings of Machine Learning and Systems</i>,
    Vol. 6, 2024.'
  ieee: 'E. Frantar and D.-A. Alistarh, “QMoE: Sub-1-bit compression of trillion parameter
    models,” in <i>Proceedings of Machine Learning and Systems</i>, Santa Clara, CA,
    United States, 2024, vol. 6.'
  ista: 'Frantar E, Alistarh D-A. 2024. QMoE: Sub-1-bit compression of trillion parameter
    models. Proceedings of Machine Learning and Systems. MLSys: Machine Learning and
    Systems vol. 6.'
  mla: 'Frantar, Elias, and Dan-Adrian Alistarh. “QMoE: Sub-1-Bit Compression of Trillion
    Parameter Models.” <i>Proceedings of Machine Learning and Systems</i>, vol. 6,
    2024.'
  short: E. Frantar, D.-A. Alistarh, in:, Proceedings of Machine Learning and Systems,
    2024.
conference:
  end_date: 2024-05-16
  location: Santa Clara, CA, United States
  name: 'MLSys: Machine Learning and Systems'
  start_date: 2024-05-13
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-13T10:01:38Z
date_published: 2024-05-01T00:00:00Z
date_updated: 2026-10-02T11:19:46Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
intvolume: '         6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://proceedings.mlsys.org/paper_files/paper/2024/hash/c74b624843218d9b6713fcf299d6d5e4-Abstract-Conference.html
month: '05'
oa: 1
oa_version: Published Version
publication: Proceedings of Machine Learning and Systems
publication_status: published
quality_controlled: '1'
related_material:
  record:
  - id: '17485'
    relation: dissertation_contains
    status: public
researchdata_availability: yes
status: public
supplementarymaterial: no
title: 'QMoE: Sub-1-bit compression of trillion parameter models'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2024'
...
---
OA_place: publisher
_id: '17490'
abstract:
- lang: eng
  text: "Deep learning is essential in numerous applications nowadays, with many recent
    advancements made possible by training very large models. Despite their broad
    applicability, training neural networks is often time-intensive, and it is usually
    impractical to manage large models and datasets on a single machine. To address
    these issues, distributed deep learning training has become increasingly important.
    However, distributed training requires synchronization among nodes, and the mini-batch
    stochastic gradient descent algorithm places a significant load on network connections.
    A possible solution to tackle the synchronization bottleneck is to reduce a message
    size by lossy compression.\r\n\r\nIn this thesis, we investigate systems and algorithmic
    approaches to communication compression during training. From the systems perspective,
    we demonstrate that a common approach of expensive hardware overprovisioning can
    be replaced through a thorough system design. We introduce a framework that introduces
    efficient software support for compressed communication in machine learning applications,
    applicable to both multi-GPU single-node training and larger-scale multi-node
    training. Our framework integrates with popular ML frameworks, providing up to
    3x speedups for multi-GPU nodes based on commodity hardware and order-of-magnitude
    improvements in the multi-node setting, with negligible impact on accuracy.\r\n\r\nAlso,
    we consider an application of our framework to different communication schemes,
    such as Fully Sharded Data Parallel. We provide strong convergence guarantees
    for the compression in such a setup. Empirical validation shows that our method
    preserves model accuracy for GPT-family models with up to 1.3 billion parameters,
    while completely removing the communication bottlenecks of non-compressed alternatives,
    providing up to 2.2x speedups end-to-end.\r\n\r\nFrom the algorithmic side, we
    propose a general framework that dynamically adjusts the degree of compression
    across a model's layers during training. This approach enhances overall compression
    and results in significant speedups without compromising accuracy. Our algorithm
    utilizes an adaptive algorithm that automatically selects the optimal compression
    parameters for model layers, ensuring the best compression ratio while adhering
    to an error constraint. Our method is effective across all existing families of
    compression methods. It achieves up to 2.5x faster training and up to a 5x improvement
    in compression compared to efficient implementations of current approaches. Additionally,
    LGreCo can complement existing adaptive algorithms.\r\n"
acknowledged_ssus:
- _id: ScienComp
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Ilia
  full_name: Markov, Ilia
  id: D0CF4148-C985-11E9-8066-0BDEE5697425
  last_name: Markov
citation:
  ama: 'Markov I. Communication-efficient distributed training of deep neural networks :
    An algorithms and systems perspective. 2024. doi:<a href="https://doi.org/10.15479/at:ista:17490">10.15479/at:ista:17490</a>'
  apa: 'Markov, I. (2024). <i>Communication-efficient distributed training of deep
    neural networks : An algorithms and systems perspective</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/at:ista:17490">https://doi.org/10.15479/at:ista:17490</a>'
  chicago: 'Markov, Ilia. “Communication-Efficient Distributed Training of Deep Neural
    Networks : An Algorithms and Systems Perspective.” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/at:ista:17490">https://doi.org/10.15479/at:ista:17490</a>.'
  ieee: 'I. Markov, “Communication-efficient distributed training of deep neural networks :
    An algorithms and systems perspective,” Institute of Science and Technology Austria,
    2024.'
  ista: 'Markov I. 2024. Communication-efficient distributed training of deep neural
    networks : An algorithms and systems perspective. Institute of Science and Technology
    Austria.'
  mla: 'Markov, Ilia. <i>Communication-Efficient Distributed Training of Deep Neural
    Networks : An Algorithms and Systems Perspective</i>. Institute of Science and
    Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:17490">10.15479/at:ista:17490</a>.'
  short: 'I. Markov, Communication-Efficient Distributed Training of Deep Neural Networks :
    An Algorithms and Systems Perspective, Institute of Science and Technology Austria,
    2024.'
corr_author: '1'
das_tickbox: '0'
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department:
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- _id: DaAl
doi: 10.15479/at:ista:17490
doi_confirm: '1'
ec_funded: 1
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publisher: Institute of Science and Technology Austria
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supervisor:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
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supplementarymaterial: no
title: 'Communication-efficient distributed training of deep neural networks : An
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user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
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...
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abstract:
- lang: eng
  text: "Data-parallel distributed training of deep neural networks (DNN) has gained
    very widespread adoption, but can still experience communication bottlenecks.
    To address this issue, entire families of compression mechanisms have been developed,
    including quantization, sparsification, and low-rank approximation, some of which
    are seeing significant practical adoption. Despite this progress, almost all known
    compression schemes apply compression uniformly across DNN layers, although layers
    are heterogeneous in terms of parameter count and their impact on model accuracy.In
    this work, we provide a general framework for adapting the degree of compression
    across the model's layers dynamically during training, improving the overall compression,
    while leading to substantial speedups, without sacrificing accuracy. Our framework,
    called L-GreCo, is based on an adaptive algorithm, which automatically picks the
    optimal compression parameters for model layers guaranteeing the best compression
    ratio while satisfying an error constraint. Extensive experiments over image classification
    and language modeling tasks shows that L-GreCo is effective across all existing
    families of compression methods, and achieves up to 2.5\r\n×\r\n training speedup
    and up to 5\r\n×\r\n compression improvement over efficient implementations of
    existing approaches, while recovering full accuracy. Moreover, L-GreCo is complementary
    to existing adaptive algorithms, improving their compression ratio by 50\\% and
    practical throughput by 66\\%. An anonymized implementation is available at https://github.com/LGrCo/L-GreCo."
article_processing_charge: No
arxiv: 1
author:
- first_name: Ilia
  full_name: Markov, Ilia
  id: D0CF4148-C985-11E9-8066-0BDEE5697425
  last_name: Markov
- first_name: Kaveh
  full_name: Alimohammadi, Kaveh
  last_name: Alimohammadi
- first_name: Elias
  full_name: Frantar, Elias
  id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f
  last_name: Frantar
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Markov I, Alimohammadi K, Frantar E, Alistarh D-A. L-GreCo: Layerwise-adaptive
    gradient compression for efficient data-parallel deep learning. In: Gibbons P,
    Pekhimenko G, De Sa C, eds. <i>Proceedings of Machine Learning and Systems </i>.
    Vol 6. Association for Computing Machinery; 2024.'
  apa: 'Markov, I., Alimohammadi, K., Frantar, E., &#38; Alistarh, D.-A. (2024). L-GreCo:
    Layerwise-adaptive gradient compression for efficient data-parallel deep learning.
    In P. Gibbons, G. Pekhimenko, &#38; C. De Sa (Eds.), <i>Proceedings of Machine
    Learning and Systems </i> (Vol. 6). Athens, Greece: Association for Computing
    Machinery.'
  chicago: 'Markov, Ilia, Kaveh Alimohammadi, Elias Frantar, and Dan-Adrian Alistarh.
    “L-GreCo: Layerwise-Adaptive Gradient Compression for Efficient Data-Parallel
    Deep Learning.” In <i>Proceedings of Machine Learning and Systems </i>, edited
    by P. Gibbons, G. Pekhimenko, and C. De Sa, Vol. 6. Association for Computing
    Machinery, 2024.'
  ieee: 'I. Markov, K. Alimohammadi, E. Frantar, and D.-A. Alistarh, “L-GreCo: Layerwise-adaptive
    gradient compression for efficient data-parallel deep learning,” in <i>Proceedings
    of Machine Learning and Systems </i>, Athens, Greece, 2024, vol. 6.'
  ista: 'Markov I, Alimohammadi K, Frantar E, Alistarh D-A. 2024. L-GreCo: Layerwise-adaptive
    gradient compression for efficient data-parallel deep learning. Proceedings of
    Machine Learning and Systems . MLSys: Machine Learning and Systems vol. 6.'
  mla: 'Markov, Ilia, et al. “L-GreCo: Layerwise-Adaptive Gradient Compression for
    Efficient Data-Parallel Deep Learning.” <i>Proceedings of Machine Learning and
    Systems </i>, edited by P. Gibbons et al., vol. 6, Association for Computing Machinery,
    2024.'
  short: I. Markov, K. Alimohammadi, E. Frantar, D.-A. Alistarh, in:, P. Gibbons,
    G. Pekhimenko, C. De Sa (Eds.), Proceedings of Machine Learning and Systems ,
    Association for Computing Machinery, 2024.
conference:
  end_date: 2024-04-22
  location: Athens, Greece
  name: 'MLSys: Machine Learning and Systems'
  start_date: 2024-04-22
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das_tickbox: '0'
date_created: 2024-08-22T08:29:25Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2026-10-02T11:20:05Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
editor:
- first_name: P.
  full_name: Gibbons, P.
  last_name: Gibbons
- first_name: G.
  full_name: Pekhimenko, G.
  last_name: Pekhimenko
- first_name: C.
  full_name: De Sa, C.
  last_name: De Sa
external_id:
  arxiv:
  - '2210.17357'
intvolume: '         6'
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- iso: eng
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title: 'L-GreCo: Layerwise-adaptive gradient compression for efficient data-parallel
  deep learning'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2024'
...
---
OA_place: publisher
_id: '18766'
abstract:
- lang: eng
  text: Poxviruses are large pleomorphic double-stranded DNA viruses that include
    well known members such as variola virus, the causative agent of smallpox, Mpox
    virus, as well as Vaccinia virus (VACV), which serves as a vaccination strain
    for formerly mentioned viruses. VACV is a valuable model for studying large pleomorphic
    DNA viruses in general and poxviruses specifically, as many features, such as
    core morphology and structural proteins, are well conserved within this family.
    Despite decades of research, our understanding of the structural components and
    proteins that comprise the poxvirus core in mature virions remains limited. Although
    major core proteins were identified via indirect experimental evidence, the core's
    complexity, with its large size, structure and number of involved proteins, has
    hindered efforts to achieve high-resolution insights and to define the roles of
    the individual proteins. The specific protein composition of the core's individual
    layers, including the palisade layer and the inner core wall, has remained unclear.
    In this study, we have merged multiple approaches, including single particle cryo
    electron microscopy of purified virus cores, cryo-electron tomography and subtomogram
    averaging of mature virions and molecular modeling to elucidate the structural
    determinants of the VACV core. Due to the lack of experimentally derived structures,
    either in situ or reconstituted in vitro, we used Alphafold to predict models
    of the putative major core protein candidates, A10, 23k, A3, A4, and L4. Our results
    show that the VACV core is composed of several layers with varying local symmetries,
    forming more intricate interactions than observed previously. This allowed us
    to identify several molecular building blocks forming the viral core lattice.
    In particular, we identified trimers of protein A10 as a major core structure
    that forms the palisade layer of the viral core. Additionally, we revealed that
    six petals of a flower shaped core pore within the core wall are composed of A10
    trimers. Furthermore, we obtained a cryo-EM density for the inner core wall that
    could potentially accommodate an A3 dimer. Integrating descriptions of protein
    interactions from previous studies enabled us to provide a detailed structural
    model of the poxvirus core wall, and our findings indicate that the interactions
    within A10 trimers are likely consistent across orthopox- and parapoxviruses.
    This combined application of cryo-SPA and cryo-ET can help overcome obstacles
    in studying complex virus structures in the future, including their key assembly
    proteins, interactions, and the formation into a core lattice. Our work provides
    important fundamental new insights into poxvirus core architecture, also considering
    the recent re-emergence of poxviruses.
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
- _id: ScienComp
acknowledgement: "This work was funded by the Austrian Science Fund (FWF) grant P31445
  and ISTA. I\r\nwould like to express my gratitude to the Scientific Service Units,
  particularly the Lab\r\nSupport Facility, the Scientific Computing Facility and
  the Electron Microscopy Facility\r\nfor their tremendous support. I want to especially
  thank Alois for assisting me with the\r\ninstallation of countless new software
  and for troubleshooting cluster issues. A special\r\nthanks goes to Valentin for
  his outstanding support in cryo-EM data acquisition and\r\nhis ongoing help in improving
  the process to ensure that I obtained the best possible\r\ndata from my sample."
alternative_title:
- ISTA thesis
article_processing_charge: No
author:
- first_name: Julia
  full_name: Datler, Julia
  id: 3B12E2E6-F248-11E8-B48F-1D18A9856A87
  last_name: Datler
  orcid: 0000-0002-3616-8580
citation:
  ama: Datler J. Elucidating the structural determinants of the poxvirus core using
    multi-modal cryo-EM. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18766">10.15479/at:ista:18766</a>
  apa: Datler, J. (2024). <i>Elucidating the structural determinants of the poxvirus
    core using multi-modal cryo-EM</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/at:ista:18766">https://doi.org/10.15479/at:ista:18766</a>
  chicago: Datler, Julia. “Elucidating the Structural Determinants of the Poxvirus
    Core Using Multi-Modal Cryo-EM.” Institute of Science and Technology Austria,
    2024. <a href="https://doi.org/10.15479/at:ista:18766">https://doi.org/10.15479/at:ista:18766</a>.
  ieee: J. Datler, “Elucidating the structural determinants of the poxvirus core using
    multi-modal cryo-EM,” Institute of Science and Technology Austria, 2024.
  ista: Datler J. 2024. Elucidating the structural determinants of the poxvirus core
    using multi-modal cryo-EM. Institute of Science and Technology Austria.
  mla: Datler, Julia. <i>Elucidating the Structural Determinants of the Poxvirus Core
    Using Multi-Modal Cryo-EM</i>. Institute of Science and Technology Austria, 2024,
    doi:<a href="https://doi.org/10.15479/at:ista:18766">10.15479/at:ista:18766</a>.
  short: J. Datler, Elucidating the Structural Determinants of the Poxvirus Core Using
    Multi-Modal Cryo-EM, Institute of Science and Technology Austria, 2024.
corr_author: '1'
das_tickbox: '1'
date_created: 2025-01-07T10:23:12Z
date_published: 2024-12-30T00:00:00Z
date_updated: 2026-10-02T11:21:19Z
day: '30'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: FlSc
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keyword:
- cryo-EM
- cryo-ET
- cryo-SPA
- Structural Virology
- Poxvirus
- Vaccinia Virus
- Structural Biology
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '106'
project:
- _id: 26736D6A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P31445
  name: Structural conservation and diversity in retroviral capsid
publication_identifier:
  isbn:
  - 978-3-99078-049-7
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
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researchdata_availability: yes
status: public
supervisor:
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
supplementarymaterial: no
title: Elucidating the structural determinants of the poxvirus core using multi-modal
  cryo-EM
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  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
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...
---
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abstract:
- lang: eng
  text: Poxviruses are among the largest double-stranded DNA viruses, with members
    such as variola virus, monkeypox virus and the vaccination strain vaccinia virus
    (VACV). Knowledge about the structural proteins that form the viral core has remained
    sparse. While major core proteins have been annotated via indirect experimental
    evidence, their structures have remained elusive and they could not be assigned
    to individual core features. Hence, which proteins constitute which layers of
    the core, such as the palisade layer and the inner core wall, has remained enigmatic.
    Here we show, using a multi-modal cryo-electron microscopy (cryo-EM) approach
    in combination with AlphaFold molecular modeling, that trimers formed by the cleavage
    product of VACV protein A10 are the key component of the palisade layer. This
    allows us to place previously obtained descriptions of protein interactions within
    the core wall into perspective and to provide a detailed model of poxvirus core
    architecture. Importantly, we show that interactions within A10 trimers are likely
    generalizable over members of orthopox- and parapoxviruses.
acknowledged_ssus:
- _id: ScienComp
- _id: LifeSc
- _id: EM-Fac
acknowledgement: "We thank A. Bergthaler (Research Center for Molecular Medicine of
  the Austrian Academy of Sciences) for providing VACV WR. We thank A. Nicholas and
  his team at the ISTA proteomics facility, and S. Elefante at the ISTA Scientific
  Computing facility for their support. We also thank F. Fäßler, D. Porley, T. Muthspiel
  and other members of the Schur group for support and helpful discussions. We also
  thank D. Castaño-Díez for support with Dynamo. We thank D. Farrell for his help
  optimizing the Rosetta protocol to refine the atomic model into the cryo-EM map
  with symmetry.\r\n\r\nF.K.M.S. acknowledges support from ISTA and EMBO. F.K.M.S.
  also received support from the Austrian Science Fund (FWF) grant P31445. This publication
  has been made possible in part by CZI grant DAF2021-234754 and grant https://doi.org/10.37921/812628ebpcwg
  from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community
  Foundation (funder https://doi.org/10.13039/100014989) awarded to F.K.M.S.\r\n\r\nThis
  research was also supported by the Scientific Service Units (SSUs) of ISTA through
  resources provided by Scientific Computing (SciComp), the Life Science Facility
  (LSF), and the Electron Microscopy Facility (EMF). We also acknowledge the use of
  COSMIC45 and Colabfold46."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Julia
  full_name: Datler, Julia
  id: 3B12E2E6-F248-11E8-B48F-1D18A9856A87
  last_name: Datler
  orcid: 0000-0002-3616-8580
- first_name: Jesse
  full_name: Hansen, Jesse
  id: 1063c618-6f9b-11ec-9123-f912fccded63
  last_name: Hansen
  orcid: 0000-0001-7967-2085
- first_name: Andreas
  full_name: Thader, Andreas
  id: 3A18A7B8-F248-11E8-B48F-1D18A9856A87
  last_name: Thader
- first_name: Alois
  full_name: Schlögl, Alois
  id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
  last_name: Schlögl
  orcid: 0000-0002-5621-8100
- first_name: Lukas W
  full_name: Bauer, Lukas W
  id: 0c894dcf-897b-11ed-a09c-8186353224b0
  last_name: Bauer
- first_name: Victor-Valentin
  full_name: Hodirnau, Victor-Valentin
  id: 3661B498-F248-11E8-B48F-1D18A9856A87
  last_name: Hodirnau
  orcid: 0000-0003-3904-947X
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
citation:
  ama: Datler J, Hansen J, Thader A, et al. Multi-modal cryo-EM reveals trimers of
    protein A10 to form the palisade layer in poxvirus cores. <i>Nature Structural
    &#38; Molecular Biology</i>. 2024;31:1114-1123. doi:<a href="https://doi.org/10.1038/s41594-023-01201-6">10.1038/s41594-023-01201-6</a>
  apa: Datler, J., Hansen, J., Thader, A., Schlögl, A., Bauer, L. W., Hodirnau, V.-V.,
    &#38; Schur, F. K. (2024). Multi-modal cryo-EM reveals trimers of protein A10
    to form the palisade layer in poxvirus cores. <i>Nature Structural &#38; Molecular
    Biology</i>. Springer Nature. <a href="https://doi.org/10.1038/s41594-023-01201-6">https://doi.org/10.1038/s41594-023-01201-6</a>
  chicago: Datler, Julia, Jesse Hansen, Andreas Thader, Alois Schlögl, Lukas W Bauer,
    Victor-Valentin Hodirnau, and Florian KM Schur. “Multi-Modal Cryo-EM Reveals Trimers
    of Protein A10 to Form the Palisade Layer in Poxvirus Cores.” <i>Nature Structural
    &#38; Molecular Biology</i>. Springer Nature, 2024. <a href="https://doi.org/10.1038/s41594-023-01201-6">https://doi.org/10.1038/s41594-023-01201-6</a>.
  ieee: J. Datler <i>et al.</i>, “Multi-modal cryo-EM reveals trimers of protein A10
    to form the palisade layer in poxvirus cores,” <i>Nature Structural &#38; Molecular
    Biology</i>, vol. 31. Springer Nature, pp. 1114–1123, 2024.
  ista: Datler J, Hansen J, Thader A, Schlögl A, Bauer LW, Hodirnau V-V, Schur FK.
    2024. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade
    layer in poxvirus cores. Nature Structural &#38; Molecular Biology. 31, 1114–1123.
  mla: Datler, Julia, et al. “Multi-Modal Cryo-EM Reveals Trimers of Protein A10 to
    Form the Palisade Layer in Poxvirus Cores.” <i>Nature Structural &#38; Molecular
    Biology</i>, vol. 31, Springer Nature, 2024, pp. 1114–23, doi:<a href="https://doi.org/10.1038/s41594-023-01201-6">10.1038/s41594-023-01201-6</a>.
  short: J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau,
    F.K. Schur, Nature Structural &#38; Molecular Biology 31 (2024) 1114–1123.
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: "The electron microscopy density maps of the A10 trimer
  and the hexameric flower-shaped pore, the subtomogram average of the palisade layer
  and representative tomograms for complete viruses as well as isolated cores have
  been deposited in the Electron Microscopy Data Bank under accession codes: EMD-17410,
  EMD-17411, EMD-17412, EMD-17413, EMD-17414 and EMD-18452.\r\n\r\nThe refined model
  of the A10 trimer has been deposited in the Protein Data Bank accession code: PDB
  8P4K.\r\n\r\nThe UniProt codes of VACV core proteins used for structure prediction
  are: A10 (P16715), A3 (P06440), A4 (P29191) and L4 (P03295).\r\n\r\nGenBank Protein
  IDs of variola virus A10 (ABF23487.1), monkeypox virus A10 (YP_010377118.1), rabbitpox
  virus A10 (AAS49831.1), cowpox virus A10 (ADZ29251.1), ectromelia virus A10 (NP_671631.1),
  orf virus P4a (AY386264.1), Amsacta moorei entomopoxvirus AMV139 (NP_064921.1) and
  Melanoplus sanguinipes entomopoxvirus putative core protein P4a homolog (AF063866.1)
  were used for protein sequence alignment. Source data for MS experiments are provided
  as Supplementary Information accompanying this manuscript."
date_created: 2024-02-12T09:59:45Z
date_published: 2024-07-01T00:00:00Z
date_updated: 2026-10-02T11:21:19Z
day: '01'
ddc:
- '570'
department:
- _id: FlSc
- _id: ScienComp
- _id: EM-Fac
doi: 10.1038/s41594-023-01201-6
external_id:
  isi:
  - '001158144600002'
  pmid:
  - '38316877'
file:
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  checksum: bda7bf65d81455480efaed8ca293b0db
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  file_id: '17307'
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file_date_updated: 2024-07-22T11:27:22Z
fulldoi: https://doi.org/10.1038/s41594-023-01201-6
has_accepted_license: '1'
intvolume: '        31'
isi: 1
keyword:
- Molecular Biology
- Structural Biology
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1114-1123
pmid: 1
project:
- _id: 26736D6A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P31445
  name: Structural conservation and diversity in retroviral capsid
publication: Nature Structural & Molecular Biology
publication_identifier:
  eissn:
  - 1545-9985
  issn:
  - 1545-9993
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA Website
    relation: press_release
    url: https://ista.ac.at/en/news/down-to-the-core-of-poxviruses/
  record:
  - id: '18766'
    relation: dissertation_contains
    status: public
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer
  in poxvirus cores
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 31
year: '2024'
...
---
OA_place: publisher
_id: '17850'
abstract:
- lang: eng
  text: "Understanding the relationship between a given phenotype and its underlying
    genotype or genotypes is one of the most pressing challenges of biology, as it
    lies at the heart of not only basic understanding of evolutionary theory, but
    also of practical applications in medicine and bioengineering. Understanding this
    relationship is complicated by the ubiquitous phenomenon of epistasis, wherein
    mutation effects are dependent on their genetic context. Fitness landscapes —
    representations of phenotype as a function of genotype — are being increasingly
    used as a tool to study the effects and interactions of thousands of mutations,
    but are experimentally limited to exploring a small fraction of a protein’s theoretical
    sequence space. Furthermore, not all regions of said sequence space are necessarily
    equally informative. Thus, gene selection for landscape surveys should be carefully
    considered in order to maximize the usable output of necessarily limited data.\r\n\r\nIn
    this work, we analyzed the fitness landscapes of orthologous green fluorescent
    proteins from four different species, by systematically measuring the phenotype,
    fluorescence, of tens of thousands of mutant genotypes from each protein. These
    landscapes were highly heterogeneous, with some genes being mutationally robust
    and displaying epistasis only rarely, and others being highly epistatic and mutationally
    fragile. We used this data to train machine learning models to predict fluorescence
    from genotype. Although the training data contained almost exclusively genotypes
    with less than 3% sequence divergence from the original wild-type sequences, we
    were able to create novel, functional genotypes with up to 20% sequence divergence.
    Counterintuitively however, genes with high mutational robustness and rare epistasis
    were more difficult to introduce large numbers of mutations into, not less. This
    represents the first study of large-scale fitness landscapes of a protein family,
    and provides insights into how to approach future landscape surveys and their
    applications in novel protein design."
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: ScienComp
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Louisa
  full_name: Gonzalez Somermeyer, Louisa
  id: 4720D23C-F248-11E8-B48F-1D18A9856A87
  last_name: Gonzalez Somermeyer
  orcid: 0000-0001-9139-5383
citation:
  ama: Gonzalez Somermeyer L. Fitness landscapes of orthologous green fluorescent
    proteins. 2024. doi:<a href="https://doi.org/10.15479/at:ista:17850">10.15479/at:ista:17850</a>
  apa: Gonzalez Somermeyer, L. (2024). <i>Fitness landscapes of orthologous green
    fluorescent proteins</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:17850">https://doi.org/10.15479/at:ista:17850</a>
  chicago: Gonzalez Somermeyer, Louisa. “Fitness Landscapes of Orthologous Green Fluorescent
    Proteins.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:17850">https://doi.org/10.15479/at:ista:17850</a>.
  ieee: L. Gonzalez Somermeyer, “Fitness landscapes of orthologous green fluorescent
    proteins,” Institute of Science and Technology Austria, 2024.
  ista: Gonzalez Somermeyer L. 2024. Fitness landscapes of orthologous green fluorescent
    proteins. Institute of Science and Technology Austria.
  mla: Gonzalez Somermeyer, Louisa. <i>Fitness Landscapes of Orthologous Green Fluorescent
    Proteins</i>. Institute of Science and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:17850">10.15479/at:ista:17850</a>.
  short: L. Gonzalez Somermeyer, Fitness Landscapes of Orthologous Green Fluorescent
    Proteins, Institute of Science and Technology Austria, 2024.
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-06T12:57:44Z
date_published: 2024-09-06T00:00:00Z
date_updated: 2026-10-02T11:21:41Z
day: '06'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: FyKo
doi: 10.15479/at:ista:17850
doi_confirm: '1'
ec_funded: 1
file:
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  creator: lgonzale
  date_created: 2024-09-27T10:32:33Z
  date_updated: 2024-09-27T10:32:33Z
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  creator: lgonzale
  date_created: 2024-09-27T10:34:34Z
  date_updated: 2024-09-27T10:34:34Z
  file_id: '18152'
  file_name: louisa_thesis_draft__240904b.docx
  file_size: 43338677
  relation: source_file
file_date_updated: 2024-09-27T10:34:34Z
fulldoi: https://doi.org/10.15479/at:ista:17850
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '89'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 26580278-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771209'
  name: Characterizing the fitness landscape on population and global scales
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  link:
  - relation: software
    url: https://github.com/aequorea238/Orthologous_GFP_Fitness_Peaks
  record:
  - id: '11448'
    relation: part_of_dissertation
    status: public
researchdata_availability: no
status: public
supervisor:
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
supplementarymaterial: no
title: Fitness landscapes of orthologous green fluorescent proteins
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '14901'
abstract:
- lang: eng
  text: Global services like navigation, communication, and Earth observation have
    increased dramatically in the 21st century due to advances in outer space industries.
    But as orbits become increasingly crowded with both satellites and inevitable
    space debris pollution, continued operations become endangered by the heightened
    risks of debris collisions in orbit. Kessler Syndrome is the term for when a critical
    threshold of orbiting debris triggers a runaway positive feedback loop of debris
    collisions, creating debris congestion that can render orbits unusable. As this
    potential tipping point becomes more widely recognized, there have been renewed
    calls for debris mitigation and removal. Here, we combine complex systems and
    social-ecological systems approaches to study how these efforts may affect space
    debris accumulation and the likelihood of reaching Kessler Syndrome. Specifically,
    we model how debris levels are affected by future launch rates, cleanup activities,
    and collisions between extant debris. We contextualize and interpret our dynamic
    model within a discussion of existing space debris governance and other social,
    economic, and geopolitical factors that may influence effective collective management
    of the orbital commons. In line with previous studies, our model finds that debris
    congestion may be reached in less than 200 years, though a holistic management
    strategy combining removal and mitigation actions can avoid such outcomes while
    continuing space activities. Moreover, although active debris removal may be particularly
    effective, the current lack of market and governance support may impede its implementation.
    Research into these critical dynamics and the multi-faceted variables that influence
    debris outcomes can support policymakers in curating impactful governance strategies
    and realistic transition pathways to sustaining debris-free orbits. Overall, our
    study is useful for communicating about space debris sustainability in policy
    and education settings by providing an exploration of policy portfolio options
    supported by a simple and clear social-ecological modeling approach.
acknowledgement: The authors would like to thank the special issue co-editors, Marco
  Janssen and Xiao-Shan Yap, and the anonymous reviewers for their comments that helped
  improve the manuscript. The paper also benefited from suggestions by other author
  participants in this special issue. We would also like to thank the 2022 Santa Fe
  Institute Complex Systems Summer School for providing space to initiate this study.
article_processing_charge: Yes
article_type: original
author:
- first_name: Keiko
  full_name: Nomura, Keiko
  last_name: Nomura
- first_name: Simon
  full_name: Rella, Simon
  id: B4765ACA-AA38-11E9-AC9A-0930E6697425
  last_name: Rella
- first_name: Haily
  full_name: Merritt, Haily
  last_name: Merritt
- first_name: Mathieu
  full_name: Baltussen, Mathieu
  last_name: Baltussen
- first_name: Darcy
  full_name: Bird, Darcy
  last_name: Bird
- first_name: Annika
  full_name: Tjuka, Annika
  last_name: Tjuka
- first_name: Dan
  full_name: Falk, Dan
  last_name: Falk
citation:
  ama: Nomura K, Rella S, Merritt H, et al. Tipping points of space debris in low
    earth orbit. <i>International Journal of the Commons</i>. 2024;18(1). doi:<a href="https://doi.org/10.5334/ijc.1275">10.5334/ijc.1275</a>
  apa: Nomura, K., Rella, S., Merritt, H., Baltussen, M., Bird, D., Tjuka, A., &#38;
    Falk, D. (2024). Tipping points of space debris in low earth orbit. <i>International
    Journal of the Commons</i>. Ubiquity Press. <a href="https://doi.org/10.5334/ijc.1275">https://doi.org/10.5334/ijc.1275</a>
  chicago: Nomura, Keiko, Simon Rella, Haily Merritt, Mathieu Baltussen, Darcy Bird,
    Annika Tjuka, and Dan Falk. “Tipping Points of Space Debris in Low Earth Orbit.”
    <i>International Journal of the Commons</i>. Ubiquity Press, 2024. <a href="https://doi.org/10.5334/ijc.1275">https://doi.org/10.5334/ijc.1275</a>.
  ieee: K. Nomura <i>et al.</i>, “Tipping points of space debris in low earth orbit,”
    <i>International Journal of the Commons</i>, vol. 18, no. 1. Ubiquity Press, 2024.
  ista: Nomura K, Rella S, Merritt H, Baltussen M, Bird D, Tjuka A, Falk D. 2024.
    Tipping points of space debris in low earth orbit. International Journal of the
    Commons. 18(1).
  mla: Nomura, Keiko, et al. “Tipping Points of Space Debris in Low Earth Orbit.”
    <i>International Journal of the Commons</i>, vol. 18, no. 1, Ubiquity Press, 2024,
    doi:<a href="https://doi.org/10.5334/ijc.1275">10.5334/ijc.1275</a>.
  short: K. Nomura, S. Rella, H. Merritt, M. Baltussen, D. Bird, A. Tjuka, D. Falk,
    International Journal of the Commons 18 (2024).
das_tickbox: '0'
date_created: 2024-01-30T11:58:02Z
date_published: 2024-01-11T00:00:00Z
date_updated: 2026-10-02T11:22:03Z
day: '11'
ddc:
- '550'
department:
- _id: GradSch
- _id: GaTk
doi: 10.5334/ijc.1275
file:
- access_level: open_access
  checksum: b80ebc889033c365d8f8c05a0c655382
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-05T10:06:35Z
  date_updated: 2024-02-05T10:06:35Z
  file_id: '14939'
  file_name: 2023_IntJourCommons_Nomura.pdf
  file_size: 1305786
  relation: main_file
  success: 1
file_date_updated: 2024-02-05T10:06:35Z
fulldoi: https://doi.org/10.5334/ijc.1275
has_accepted_license: '1'
intvolume: '        18'
issue: '1'
keyword:
- Sociology and Political Science
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: International Journal of the Commons
publication_identifier:
  issn:
  - 1875-0281
publication_status: published
publisher: Ubiquity Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Tipping points of space debris in low earth orbit
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 18
year: '2024'
...
---
OA_place: publisher
_id: '18076'
abstract:
- lang: eng
  text: "The new era of Ge has opened up new possibilities in quantum computing. The
    maturity of Ge\r\nspin qubits is unquestioned, while hybrid semiconductor-superconductor
    Ge circuits are on track\r\nto enter the game. Gate-tunable transmons (gatemons)
    employing semiconductor Josephson\r\njunctions have recently emerged as building
    blocks for such hybrid quantum circuits. In this\r\nthesis, we present a gatemon
    fabricated in planar Germanium. We induce superconductivity\r\nin a two-dimensional
    hole gas by evaporating aluminum atop a thin spacer, which separates\r\nthe superconductor
    from the Ge quantum well. The Josephson junction is then integrated\r\ninto an
    Xmon circuit and capacitively coupled to a transmission line resonator. We showcase\r\nthe
    qubit tunability in a broad frequency range with resonator and two-tone spectroscopy.\r\nTime-domain
    characterizations reveal energy relaxation and coherence times up to 75 ns. Our\r\nresults,
    combined with the recent advances in the spin qubit field, pave the way towards
    novel\r\nhybrid and protected qubits in a group IV, CMOS-compatible material."
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Oliver
  full_name: Sagi, Oliver
  id: 71616374-A8E9-11E9-A7CA-09ECE5697425
  last_name: Sagi
citation:
  ama: Sagi O. Hybrid circuits on planar Germanium. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18076">10.15479/at:ista:18076</a>
  apa: Sagi, O. (2024). <i>Hybrid circuits on planar Germanium</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18076">https://doi.org/10.15479/at:ista:18076</a>
  chicago: Sagi, Oliver. “Hybrid Circuits on Planar Germanium.” Institute of Science
    and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18076">https://doi.org/10.15479/at:ista:18076</a>.
  ieee: O. Sagi, “Hybrid circuits on planar Germanium,” Institute of Science and Technology
    Austria, 2024.
  ista: Sagi O. 2024. Hybrid circuits on planar Germanium. Institute of Science and
    Technology Austria.
  mla: Sagi, Oliver. <i>Hybrid Circuits on Planar Germanium</i>. Institute of Science
    and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18076">10.15479/at:ista:18076</a>.
  short: O. Sagi, Hybrid Circuits on Planar Germanium, Institute of Science and Technology
    Austria, 2024.
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-16T12:58:36Z
date_published: 2024-09-18T00:00:00Z
date_updated: 2026-10-02T11:22:29Z
day: '18'
ddc:
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: GeKa
doi: 10.15479/at:ista:18076
doi_confirm: '1'
ec_funded: 1
file:
- access_level: open_access
  checksum: d01d0e2846c2f3ac5bb14d321554a4cd
  content_type: application/pdf
  creator: osagi
  date_created: 2024-09-18T14:13:01Z
  date_updated: 2024-09-18T14:13:01Z
  file_id: '18093'
  file_name: OliverSagi_Thesis_pdfa.pdf
  file_size: 86679095
  relation: main_file
  success: 1
- access_level: local
  checksum: 0543f473d509ee545f4ed3a56f742f4b
  content_type: application/x-zip-compressed
  creator: osagi
  date_created: 2024-09-18T14:14:02Z
  date_updated: 2024-09-19T09:20:33Z
  file_id: '18094'
  file_name: Thesis_OliverSagi.zip
  file_size: 172098524
  relation: source_file
file_date_updated: 2024-09-19T09:20:33Z
fulldoi: https://doi.org/10.15479/at:ista:18076
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '111'
project:
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
- _id: c0977eea-5a5b-11eb-8a69-a862db0cf4d1
  grant_number: I05060
  name: High impedance circuit quantum electrodynamics with hole spins
- _id: 262116AA-B435-11E9-9278-68D0E5697425
  name: Hybrid Semiconductor - Superconductor Quantum Devices
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17202'
    relation: part_of_dissertation
    status: public
researchdata_availability: no
status: public
supervisor:
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
supplementarymaterial: yes
title: Hybrid circuits on planar Germanium
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
_id: '17170'
abstract:
- lang: eng
  text: "In this article we extend and strengthen the seminal work by Niyogi, Smale,
    and Weinberger on the learning of the homotopy type from a sample of an underlying
    space. In their work, Niyogi, Smale, and Weinberger studied samples of C² manifolds
    with positive reach embedded in ℝ^d. We extend their results in the following
    ways: - As the ambient space we consider both ℝ^d and Riemannian manifolds with
    lower bounded sectional curvature. - In both types of ambient spaces, we study
    sets of positive reach - a significantly more general setting than C² manifolds
    - as well as general manifolds of positive reach. - The sample P of a set (or
    a manifold) \U0001D4AE of positive reach may be noisy. We work with two one-sided
    Hausdorff distances - ε and δ - between P and \U0001D4AE. We provide tight bounds
    in terms of ε and δ, that guarantee that there exists a parameter r such that
    the union of balls of radius r centred at the sample P deformation-retracts to
    \U0001D4AE. We exhibit their tightness by an explicit construction. We carefully
    distinguish the roles of δ and ε. This is not only essential to achieve tight
    bounds, but also sensible in practical situations, since it allows one to adapt
    the bound according to sample density and the amount of noise present in the sample
    separately."
acknowledgement: "This research has been supported by the European Research Council
  (ERC), grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF),
  grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian
  Science Fund (FWF), grant No. I 02979-N35.\r\nWintraecken, Mathijs: Supported by
  the European Union’s Horizon 2020 research and innovation programme under the Marie
  Skłodowska-Curie grant agreement No. 754411, the Austrian science fund (FWF) grant
  No. M-3073, and the welcome package from IDEX of the Université Côte d'Azur."
alternative_title:
- LIPIcs
article_processing_charge: No
arxiv: 1
author:
- first_name: Dominique
  full_name: Attali, Dominique
  last_name: Attali
- first_name: Hana
  full_name: Kourimska, Hana
  id: D9B8E14C-3C26-11EA-98F5-1F833DDC885E
  last_name: Kourimska
  orcid: 0000-0001-7841-0091
- first_name: Christopher D
  full_name: Fillmore, Christopher D
  id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
  last_name: Fillmore
- first_name: Ishika
  full_name: Ghosh, Ishika
  id: ee449b28-344d-11ef-a6d5-9ca430e9e9ff
  last_name: Ghosh
- first_name: André
  full_name: Lieutier, André
  last_name: Lieutier
- first_name: Elizabeth R
  full_name: Stephenson, Elizabeth R
  id: 2D04F932-F248-11E8-B48F-1D18A9856A87
  last_name: Stephenson
  orcid: 0000-0002-6862-208X
- first_name: Mathijs
  full_name: Wintraecken, Mathijs
  id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
  last_name: Wintraecken
  orcid: 0000-0002-7472-2220
citation:
  ama: 'Attali D, Kourimska H, Fillmore CD, et al. Tight bounds for the learning of
    homotopy à la Niyogi, Smale, and Weinberger for subsets of euclidean spaces and
    of Riemannian manifolds. In: <i>40th International Symposium on Computational
    Geometry</i>. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024:11:1-11:19.
    doi:<a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.11">10.4230/LIPIcs.SoCG.2024.11</a>'
  apa: 'Attali, D., Kourimska, H., Fillmore, C. D., Ghosh, I., Lieutier, A., Stephenson,
    E. R., &#38; Wintraecken, M. (2024). Tight bounds for the learning of homotopy
    à la Niyogi, Smale, and Weinberger for subsets of euclidean spaces and of Riemannian
    manifolds. In <i>40th International Symposium on Computational Geometry</i> (Vol.
    293, p. 11:1-11:19). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
    <a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.11">https://doi.org/10.4230/LIPIcs.SoCG.2024.11</a>'
  chicago: Attali, Dominique, Hana Kourimska, Christopher D Fillmore, Ishika Ghosh,
    André Lieutier, Elizabeth R Stephenson, and Mathijs Wintraecken. “Tight Bounds
    for the Learning of Homotopy à La Niyogi, Smale, and Weinberger for Subsets of
    Euclidean Spaces and of Riemannian Manifolds.” In <i>40th International Symposium
    on Computational Geometry</i>, 293:11:1-11:19. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2024. <a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.11">https://doi.org/10.4230/LIPIcs.SoCG.2024.11</a>.
  ieee: D. Attali <i>et al.</i>, “Tight bounds for the learning of homotopy à la Niyogi,
    Smale, and Weinberger for subsets of euclidean spaces and of Riemannian manifolds,”
    in <i>40th International Symposium on Computational Geometry</i>, Athens, Greece,
    2024, vol. 293, p. 11:1-11:19.
  ista: 'Attali D, Kourimska H, Fillmore CD, Ghosh I, Lieutier A, Stephenson ER, Wintraecken
    M. 2024. Tight bounds for the learning of homotopy à la Niyogi, Smale, and Weinberger
    for subsets of euclidean spaces and of Riemannian manifolds. 40th International
    Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry,
    LIPIcs, vol. 293, 11:1-11:19.'
  mla: Attali, Dominique, et al. “Tight Bounds for the Learning of Homotopy à La Niyogi,
    Smale, and Weinberger for Subsets of Euclidean Spaces and of Riemannian Manifolds.”
    <i>40th International Symposium on Computational Geometry</i>, vol. 293, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2024, p. 11:1-11:19, doi:<a href="https://doi.org/10.4230/LIPIcs.SoCG.2024.11">10.4230/LIPIcs.SoCG.2024.11</a>.
  short: D. Attali, H. Kourimska, C.D. Fillmore, I. Ghosh, A. Lieutier, E.R. Stephenson,
    M. Wintraecken, in:, 40th International Symposium on Computational Geometry, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2024, p. 11:1-11:19.
conference:
  end_date: 2024-06-14
  location: Athens, Greece
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2024-06-11
das_tickbox: '0'
date_created: 2024-06-25T11:45:58Z
date_published: 2024-06-06T00:00:00Z
date_updated: 2026-10-02T11:23:43Z
day: '06'
ddc:
- '516'
department:
- _id: GradSch
- _id: HeEd
doi: 10.4230/LIPIcs.SoCG.2024.11
ec_funded: 1
external_id:
  arxiv:
  - '2206.10485'
file:
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fulldoi: https://doi.org/10.4230/LIPIcs.SoCG.2024.11
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intvolume: '       293'
language:
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month: '06'
oa: 1
oa_version: Published Version
page: 11:1-11:19
project:
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  call_identifier: H2020
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publication: 40th International Symposium on Computational Geometry
publication_identifier:
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  isbn:
  - '9783959773164'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
researchdata_availability: no
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status: public
supplementarymaterial: no
title: Tight bounds for the learning of homotopy à la Niyogi, Smale, and Weinberger
  for subsets of euclidean spaces and of Riemannian manifolds
tmp:
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type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 293
year: '2024'
...
---
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abstract:
- lang: eng
  text: Gate-tunable transmons (gatemons) employing semiconductor Josephson junctions
    have recently emerged as building blocks for hybrid quantum circuits. In this
    study, we present a gatemon fabricated in planar Germanium. We induce superconductivity
    in a two-dimensional hole gas by evaporating aluminum atop a thin spacer, which
    separates the superconductor from the Ge quantum well. The Josephson junction
    is then integrated into an Xmon circuit and capacitively coupled to a transmission
    line resonator. We showcase the qubit tunability in a broad frequency range with
    resonator and two-tone spectroscopy. Time-domain characterizations reveal energy
    relaxation and coherence times up to 75 ns. Our results, combined with the recent
    advances in the spin qubit field, pave the way towards novel hybrid and protected
    qubits in a group IV, CMOS-compatible material.
acknowledged_ssus:
- _id: ScienComp
- _id: M-Shop
- _id: NanoFab
acknowledgement: "We acknowledge Lucas Casparis, Jeroen Danon, Valla Fatemi, Morten
  Kjaergard and Javad Shabani for their valuable insights and comments. This research
  was supported by the Scientific Service Units of ISTA through resources provided
  by the MIBA Machine Shop\r\nand the Nanofabrication facility. This research and
  related results were made possible with the support of the NOMIS Foundation and
  the FWF Projects with DOI:10.55776/I5060 and DOI:10.55776/P36507. We also acknowledge
  the NextGenerationEU PRIN project\r\n2022A8CJP3 (GAMESQUAD) for partial financial
  support."
article_number: '6400'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Oliver
  full_name: Sagi, Oliver
  id: 71616374-A8E9-11E9-A7CA-09ECE5697425
  last_name: Sagi
- first_name: Alessandro
  full_name: Crippa, Alessandro
  id: 1F2B21A2-F6E7-11E9-9B82-F7DBE5697425
  last_name: Crippa
  orcid: 0000-0002-2968-611X
- first_name: Marco
  full_name: Valentini, Marco
  id: C0BB2FAC-D767-11E9-B658-BC13E6697425
  last_name: Valentini
- first_name: Marian
  full_name: Janik, Marian
  id: 396A1950-F248-11E8-B48F-1D18A9856A87
  last_name: Janik
  orcid: 0009-0003-9037-8831
- first_name: Levon
  full_name: Baghumyan, Levon
  id: 7aa1f788-b527-11ee-aa9e-e6111a79e0c7
  last_name: Baghumyan
- first_name: Giorgio
  full_name: Fabris, Giorgio
  id: 298cf6f3-1ff6-11ee-9fa6-d94cfa0b3352
  last_name: Fabris
- first_name: Lucky
  full_name: Kapoor, Lucky
  id: 84b9700b-15b2-11ec-abd3-831089e67615
  last_name: Kapoor
  orcid: 0000-0001-8319-2148
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
- first_name: Stefano
  full_name: Calcaterra, Stefano
  last_name: Calcaterra
- first_name: Daniel
  full_name: Chrastina, Daniel
  last_name: Chrastina
- first_name: Giovanni
  full_name: Isella, Giovanni
  last_name: Isella
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Sagi O, Crippa A, Valentini M, et al. A gate tunable transmon qubit in planar
    Ge. <i>Nature Communications</i>. 2024;15. doi:<a href="https://doi.org/10.1038/s41467-024-50763-6">10.1038/s41467-024-50763-6</a>
  apa: Sagi, O., Crippa, A., Valentini, M., Janik, M., Baghumyan, L., Fabris, G.,
    … Katsaros, G. (2024). A gate tunable transmon qubit in planar Ge. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-024-50763-6">https://doi.org/10.1038/s41467-024-50763-6</a>
  chicago: Sagi, Oliver, Alessandro Crippa, Marco Valentini, Marian Janik, Levon Baghumyan,
    Giorgio Fabris, Lucky Kapoor, et al. “A Gate Tunable Transmon Qubit in Planar
    Ge.” <i>Nature Communications</i>. Springer Nature, 2024. <a href="https://doi.org/10.1038/s41467-024-50763-6">https://doi.org/10.1038/s41467-024-50763-6</a>.
  ieee: O. Sagi <i>et al.</i>, “A gate tunable transmon qubit in planar Ge,” <i>Nature
    Communications</i>, vol. 15. Springer Nature, 2024.
  ista: Sagi O, Crippa A, Valentini M, Janik M, Baghumyan L, Fabris G, Kapoor L, Hassani
    F, Fink JM, Calcaterra S, Chrastina D, Isella G, Katsaros G. 2024. A gate tunable
    transmon qubit in planar Ge. Nature Communications. 15, 6400.
  mla: Sagi, Oliver, et al. “A Gate Tunable Transmon Qubit in Planar Ge.” <i>Nature
    Communications</i>, vol. 15, 6400, Springer Nature, 2024, doi:<a href="https://doi.org/10.1038/s41467-024-50763-6">10.1038/s41467-024-50763-6</a>.
  short: O. Sagi, A. Crippa, M. Valentini, M. Janik, L. Baghumyan, G. Fabris, L. Kapoor,
    F. Hassani, J.M. Fink, S. Calcaterra, D. Chrastina, G. Isella, G. Katsaros, Nature
    Communications 15 (2024).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: All experimental data included in this work will be available
  at the ISTA Research Data Repository
date_created: 2024-07-04T11:40:45Z
date_published: 2024-07-30T00:00:00Z
date_updated: 2026-10-02T11:23:23Z
day: '30'
ddc:
- '530'
department:
- _id: GeKa
- _id: JoFi
- _id: GradSch
doi: 10.1038/s41467-024-50763-6
external_id:
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  - '2403.16774'
  isi:
  - '001281271000022'
  pmid:
  - '39080279'
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publication: Nature Communications
publication_identifier:
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publisher: Springer Nature
quality_controlled: '1'
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abstract:
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  text: This .zip File contains the data for the figures presented in the main text
    and supplementary material of "A gate tunable transmon qubit in planar Ge" by
    O.Sagi et al. The measurements were done using Qcodes. The description of the
    files and the instructions on opening the data can be found in the Readme. An
    additional Jupyter Notebook is attached that walks through the data analysis.
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: 'This research was supported by the Scientific Service Units of ISTA
  through resources provided by the MIBA Machine Shop and the Nanofabrication facility. '
article_processing_charge: No
author:
- first_name: Oliver
  full_name: Sagi, Oliver
  id: 71616374-A8E9-11E9-A7CA-09ECE5697425
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citation:
  ama: Sagi O. A gate-tunable transmon in planar Ge. 2024. doi:<a href="https://doi.org/10.15479/AT:ISTA:17196">10.15479/AT:ISTA:17196</a>
  apa: Sagi, O. (2024). A gate-tunable transmon in planar Ge. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:17196">https://doi.org/10.15479/AT:ISTA:17196</a>
  chicago: Sagi, Oliver. “A Gate-Tunable Transmon in Planar Ge.” Institute of Science
    and Technology Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:17196">https://doi.org/10.15479/AT:ISTA:17196</a>.
  ieee: O. Sagi, “A gate-tunable transmon in planar Ge.” Institute of Science and
    Technology Austria, 2024.
  ista: Sagi O. 2024. A gate-tunable transmon in planar Ge, Institute of Science and
    Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:17196">10.15479/AT:ISTA:17196</a>.
  mla: Sagi, Oliver. <i>A Gate-Tunable Transmon in Planar Ge</i>. Institute of Science
    and Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:17196">10.15479/AT:ISTA:17196</a>.
  short: O. Sagi, (2024).
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- contributor_type: project_member
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  last_name: Chrastina
- contributor_type: project_member
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  last_name: Isella
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  first_name: Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
corr_author: '1'
date_created: 2024-07-04T10:14:34Z
date_published: 2024-07-04T00:00:00Z
date_updated: 2026-10-02T11:23:23Z
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- _id: 262116AA-B435-11E9-9278-68D0E5697425
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- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
publisher: Institute of Science and Technology Austria
related_material:
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status: public
title: A gate-tunable transmon in planar Ge
tmp:
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  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
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abstract:
- lang: eng
  text: The TIR1/AFB–Aux/IAA–ARF canonical auxin signaling pathway is widely accepted
    to (de)active transcriptional regulation, thus controlling auxin-associated developmental
    processes. However, the theme of a rapid auxin response has emerged since the
    2018 Auxins and Cytokinin in Plant Development conference. To date, a few signaling
    components have been identified to mediate both slow and rapid auxin responses,
    which unveils the complexity of auxin signaling.
acknowledgement: "We thank other lab members for their critical comments on this manuscript.
  We also thank the editor and reviewers for their constructive comments to improve
  our manuscript. We apologize to authors whose important work we could not include
  due to space limitations.\r\nThis work is supported by funding from Jiangxi Agricultural
  University (9232308314) and the Science and Technology Department of Jiangxi Province
  (20223BCJ25037) to HBH, and the Science and Technology Department of Jiangxi Province
  (20202ACB215002) to SYP."
article_number: erae246
article_processing_charge: No
article_type: original
author:
- first_name: Zilin
  full_name: Zhang, Zilin
  last_name: Zhang
- first_name: Huihuang
  full_name: Chen, Huihuang
  id: 83c96512-15b2-11ec-abd3-b7eede36184f
  last_name: Chen
- first_name: Shuaiying
  full_name: Peng, Shuaiying
  last_name: Peng
- first_name: Huibin
  full_name: Han, Huibin
  last_name: Han
citation:
  ama: Zhang Z, Chen H, Peng S, Han H. Slow and rapid auxin responses in Arabidopsis.
    <i>Journal of Experimental Botany</i>. 2024;75(18). doi:<a href="https://doi.org/10.1093/jxb/erae246">10.1093/jxb/erae246</a>
  apa: Zhang, Z., Chen, H., Peng, S., &#38; Han, H. (2024). Slow and rapid auxin responses
    in Arabidopsis. <i>Journal of Experimental Botany</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/jxb/erae246">https://doi.org/10.1093/jxb/erae246</a>
  chicago: Zhang, Zilin, Huihuang Chen, Shuaiying Peng, and Huibin Han. “Slow and
    Rapid Auxin Responses in Arabidopsis.” <i>Journal of Experimental Botany</i>.
    Oxford University Press, 2024. <a href="https://doi.org/10.1093/jxb/erae246">https://doi.org/10.1093/jxb/erae246</a>.
  ieee: Z. Zhang, H. Chen, S. Peng, and H. Han, “Slow and rapid auxin responses in
    Arabidopsis,” <i>Journal of Experimental Botany</i>, vol. 75, no. 18. Oxford University
    Press, 2024.
  ista: Zhang Z, Chen H, Peng S, Han H. 2024. Slow and rapid auxin responses in Arabidopsis.
    Journal of Experimental Botany. 75(18), erae246.
  mla: Zhang, Zilin, et al. “Slow and Rapid Auxin Responses in Arabidopsis.” <i>Journal
    of Experimental Botany</i>, vol. 75, no. 18, erae246, Oxford University Press,
    2024, doi:<a href="https://doi.org/10.1093/jxb/erae246">10.1093/jxb/erae246</a>.
  short: Z. Zhang, H. Chen, S. Peng, H. Han, Journal of Experimental Botany 75 (2024).
das_tickbox: '0'
date_created: 2024-06-15T19:50:15Z
date_published: 2024-09-27T00:00:00Z
date_updated: 2026-10-02T11:25:38Z
day: '27'
ddc:
- '580'
department:
- _id: GradSch
- _id: JiFr
doi: 10.1093/jxb/erae246
external_id:
  isi:
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  pmid:
  - '38794966'
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  date_updated: 2025-01-02T10:26:22Z
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fulldoi: https://doi.org/10.1093/jxb/erae246
has_accepted_license: '1'
intvolume: '        75'
isi: 1
issue: '18'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Experimental Botany
publication_identifier:
  issn:
  - 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Slow and rapid auxin responses in Arabidopsis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 75
year: '2024'
...
