---
OA_place: publisher
OA_type: hybrid
_id: '21767'
abstract:
- lang: eng
text: 'The involvement of non-scientific staff in discussions about animal welfare
and scientific quality is essential for biomedical research progress. In this
study, we developed a survey to collect the self-perception of animal care staff
(ACS) and laboratory technicians about their involvement in scientific planning
and conduct. Participants were contacted to complete an anonymous online questionnaire.
We obtained 850 responses, mainly from Europe: 564 from ACS and 286 from laboratory
technicians. Job satisfaction was assessed as positive by ACS and laboratory technicians
despite the low frequency of culture of care activities and mental health meetings.
Both groups expressed their desire to be trained in research planning and conduct;
however, regular training was not reported. In addition, the inability to act
on animal welfare concerns owing to experimental reasons was reported by both
groups. Over half of the participants felt valued and appreciated by the lead
scientists or animal facility manager; however, it is not clear how they are acknowledged,
as their names on the authors list or in the manuscript acknowledgments are barely
included. Our results indicated that involvement of ACS and laboratory technicians
in planning and conducting studies would improve their understanding of how experiments
are done, and therefore communication processes, work satisfaction, animal welfare,
and scientific quality. Finally, we provided recommendations to improve the engagement
of ACS and laboratory technicians in discussions about animal research planning
and conduct.'
- lang: fre
text: 'La participation de personnel non-scientifique aux discussions sur le bien-être
animal et la qualité scientifique est essentielle aux progrès la recherche biomédicale.
Dans cette étude, nous avons développé une enquête pour recueillir l''auto-perception
du personnel chargé des soins prodigués aux animaux (PCSA) et des techniciens
de laboratoire (TL) sur leur implication dans la planification et la conduite
scientifiques. Les participants ont été contactés pour remplir un questionnaire
anonyme en ligne. Nous avons obtenu 850 réponses, principalement en Europe : 564
provenant de PCSA et 286 de TL. La satisfaction au travail a été évaluée comme
positive par le PCSA et les TL malgré la faible fréquence d’activités sur la culture
des soins et de réunions concernant la santé mentale. Bien que les deux groupes
aient exprimé leur désir d''être formés à la planification et à la conduite de
la recherche, aucune formation réelle régulière n''a été signalée. De plus, l''incapacité
d''agir sur les préoccupations relatives au bien-être animal pour des raisons
expérimentales a été signalée par les deux groupes. Plus de la moitié des participants
se sont sentis valorisés et appréciés par les scientifiques principaux ou le gestionnaire
de l’installation animale mais on ne sait pas clairement comment ils sont reconnus,
car leurs noms sur la liste des auteurs ou dans les remerciements sont à peine
inclus dans la documentation. Nos résultats ont indiqué que la participation du
PCSA et des TL à la planification et à la conduite des études améliorerait leur
compréhension de la façon dont les expériences sont effectuées et, par conséquent,
les processus de communication, leur satisfaction au travail ainsi que le bien-être
animal et la qualité scientifique. Enfin, nous avons formulé des recommandations
pour améliorer la participation du PCSA et des TL aux discussions sur la planification
et la conduite de la recherche animale.'
- lang: ger
text: 'Die Einbeziehung von nichtwissenschaftlichem Personal in Diskussionen über
Tierschutz und wissenschaftliche Qualität ist für Fortschritte in biomedizinischer
Forschung von entscheidender Bedeutung. In dieser Studie haben wir eine Umfrage
entwickelt, um die Selbsteinschätzung von Tierpflegern (ACS) und Labortechnikern
(LT) hinsichtlich ihrer Beteiligung an der wissenschaftlichen Planung und Durchführung
zu erfassen. Die Teilnehmer wurden gebeten, einen anonymen Online-Fragebogen auszufüllen.
Wir erhielten 850 Rückmeldungen, hauptsächlich aus Europa: 564 von ACS und 286
von LT. Die Arbeitszufriedenheit wurde von ACS und LT trotz der geringen Häufigkeit
von Pflegeaktivitäten und Treffen zum Thema psychische Gesundheit als positiv
bewertet. Beide Gruppen äußerten den Wunsch, in der Forschungsplanung und -durchführung
geschult zu werden, doch regelmäßig stattfindende Schulungen wurden nicht berichtet.
Außerdem wurde von beiden Gruppen vermeldet, dass sie aus versuchstechnischen
Gründen nicht in der Lage waren, auf Tierschutzbedenken zu reagieren. Über die
Hälfte der Teilnehmer fühlte sich von den leitenden Wissenschaftlern oder dem
Leiter der Tierhaltungseinrichtung geschätzt und anerkannt; es ist jedoch unklar,
inwiefern sie wirklich gewürdigt werden, da ihre Namen kaum in der Autorenliste
oder in den Danksagungen des Manuskripts aufgeführt sind. Unsere Ergebnisse deuteten
darauf hin, dass die Einbeziehung von ACS und LT in die Planung und Durchführung
von Studien ihr Verständnis für die Durchführung von Experimenten verbessern würde
– und damit auch Kommunikationsprozesse, Arbeitszufriedenheit, Tierwohl und wissenschaftliche
Qualität. Abschließend gaben wir Empfehlungen zur Verbesserung der Einbeziehung
von ACS und LT in Diskussionen über die Planung und Durchführung von Tierversuchen.'
- lang: spa
text: 'La participación del personal no científico en los debates sobre el bienestar
animal y la calidad científica es fundamental para el avance de la investigación
biomédica. En este estudio, desarrollamos una encuesta para recoger la autopercepción
del personal encargado del cuidado de los animales (ACS) y de los técnicos de
laboratorio (LT) sobre su implicación en la planificación y la realización científicas.
Se contactó con los participantes para que cumplimentaran un cuestionario anónimo
en línea. Obtuvimos 850 respuestas, principalmente de Europa: 564 de ACS y 286
de LT. La satisfacción laboral fue evaluada como positiva por ACS y técnicos de
laboratorio a pesar de la baja frecuencia de actividades de cultura del cuidado
y reuniones sobre bienestar mental. Ambos grupos expresaron su deseo de recibir
formación en planificación y realización de investigaciones, sin embargo, no se
informó sobre una formación regular. Asimismo, ambos grupos señalaron la incapacidad
de actuar ante las preocupaciones sobre el bienestar animal por motivos experimentales.
Más de la mitad de los participantes se sintieron valorados y apreciados por los
científicos principales o el responsable de las instalaciones de animales; sin
embargo, no está claro cómo se les reconoce, ya que apenas se incluyen sus nombres
en la lista de autores o en los agradecimientos del manuscrito. Nuestros resultados
indicaron que la participación de los ACS y los LT en la planificación y realización
de los estudios mejoraría su comprensión de cómo se hacen los experimentos y,
por tanto, los procesos de comunicación, la satisfacción laboral, el bienestar
animal y la calidad científica. Finalmente, proporcionamos recomendaciones para
mejorar el compromiso de la AEC y la LT en los debates sobre la planificación
y la realización de investigaciones con animales.'
acknowledgement: "We deeply acknowledge all the animal care staff and laboratory technicians
who participated in this study! We acknowledge Working Groups 1 and 4 from COST
Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139,
supported by COST (European Cooperation in Science and Technology) for their feedback
and support. We also acknowledge Aoife Milford for her comments and contributions
to the final draft of the manuscript.\r\nThis publication was based on work from
the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”),
CA21139, supported by COST (European Cooperation in Science and Technology)."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernando
full_name: Gonzalez-Uarquin, Fernando
last_name: Gonzalez-Uarquin
- first_name: Paulin
full_name: Jirkof, Paulin
last_name: Jirkof
- first_name: Bettina
full_name: Bert, Bettina
last_name: Bert
- first_name: Penny
full_name: Hawkins, Penny
last_name: Hawkins
- first_name: Ljupco
full_name: Angelovski, Ljupco
last_name: Angelovski
- first_name: Jan
full_name: Baumgart, Jan
last_name: Baumgart
- first_name: Nadine
full_name: Baumgart, Nadine
last_name: Baumgart
- first_name: Özge S.
full_name: Cevik, Özge S.
last_name: Cevik
- first_name: Nuno H.
full_name: Franco, Nuno H.
last_name: Franco
- first_name: Erdal
full_name: Horata, Erdal
last_name: Horata
- first_name: Rohish
full_name: Kaura, Rohish
last_name: Kaura
- first_name: Winfried
full_name: Neuhaus, Winfried
last_name: Neuhaus
- first_name: Brigida
full_name: Riso, Brigida
last_name: Riso
- first_name: Adrian J.
full_name: Smith, Adrian J.
last_name: Smith
- first_name: Athanassia
full_name: Sotiropoulos, Athanassia
last_name: Sotiropoulos
- first_name: Augusto
full_name: Vitale, Augusto
last_name: Vitale
- first_name: Sophie
full_name: Schober, Sophie
id: 80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8
last_name: Schober
citation:
ama: 'Gonzalez-Uarquin F, Jirkof P, Bert B, et al. Building bridges: Involvement
of animal care staff and laboratory technicians in experimental planning and conduct
of animal studies for better job satisfaction and science. Laboratory Animals.
2026. doi:10.1177/00236772251400976'
apa: 'Gonzalez-Uarquin, F., Jirkof, P., Bert, B., Hawkins, P., Angelovski, L., Baumgart,
J., … Schober, S. (2026). Building bridges: Involvement of animal care staff and
laboratory technicians in experimental planning and conduct of animal studies
for better job satisfaction and science. Laboratory Animals. SAGE Publications.
https://doi.org/10.1177/00236772251400976'
chicago: 'Gonzalez-Uarquin, Fernando, Paulin Jirkof, Bettina Bert, Penny Hawkins,
Ljupco Angelovski, Jan Baumgart, Nadine Baumgart, et al. “Building Bridges: Involvement
of Animal Care Staff and Laboratory Technicians in Experimental Planning and Conduct
of Animal Studies for Better Job Satisfaction and Science.” Laboratory Animals.
SAGE Publications, 2026. https://doi.org/10.1177/00236772251400976.'
ieee: 'F. Gonzalez-Uarquin et al., “Building bridges: Involvement of animal
care staff and laboratory technicians in experimental planning and conduct of
animal studies for better job satisfaction and science,” Laboratory Animals.
SAGE Publications, 2026.'
ista: 'Gonzalez-Uarquin F, Jirkof P, Bert B, Hawkins P, Angelovski L, Baumgart J,
Baumgart N, Cevik ÖS, Franco NH, Horata E, Kaura R, Neuhaus W, Riso B, Smith AJ,
Sotiropoulos A, Vitale A, Schober S. 2026. Building bridges: Involvement of animal
care staff and laboratory technicians in experimental planning and conduct of
animal studies for better job satisfaction and science. Laboratory Animals.'
mla: 'Gonzalez-Uarquin, Fernando, et al. “Building Bridges: Involvement of Animal
Care Staff and Laboratory Technicians in Experimental Planning and Conduct of
Animal Studies for Better Job Satisfaction and Science.” Laboratory Animals,
SAGE Publications, 2026, doi:10.1177/00236772251400976.'
short: F. Gonzalez-Uarquin, P. Jirkof, B. Bert, P. Hawkins, L. Angelovski, J. Baumgart,
N. Baumgart, Ö.S. Cevik, N.H. Franco, E. Horata, R. Kaura, W. Neuhaus, B. Riso,
A.J. Smith, A. Sotiropoulos, A. Vitale, S. Schober, Laboratory Animals (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-14T00:00:00Z
date_updated: 2026-06-18T08:33:36Z
day: '14'
ddc:
- '570'
department:
- _id: PreCl
doi: 10.1177/00236772251400976
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1177/00236772251400976
month: '04'
oa: 1
oa_version: Published Version
publication: Laboratory Animals
publication_identifier:
eissn:
- 1758-1117
issn:
- 0023-6772
publication_status: epub_ahead
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Building bridges: Involvement of animal care staff and laboratory technicians
in experimental planning and conduct of animal studies for better job satisfaction
and science'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21776'
abstract:
- lang: eng
text: Pyridyl motifs equipped with N-substituents can be powerful ligands for catalysis,
yet their broader adoption is limited by the lack of a practical method to prepare
these scaffolds. We report a modular, robust, and versatile Buchwald–Hartwig amination
protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine,
and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N-substituents.
These conditions streamline ligand library synthesis and will facilitate systematic
studies in catalysis and related applications.
acknowledged_ssus:
- _id: LifeSc
- _id: MassSpec
- _id: NMR
- _id: M-Shop
acknowledgement: We gratefully acknowledge ISTA for generous financial support. B.P.
acknowledges the Austrian Science Fund (PAT 1250924) and the ACS GCI Pharmaceutical
Roundtable for funding; T.P.Y acknowledges the NSF(CHE-2349003) for financial support.
This research was supported by the Scientific Service Units (SSU) of ISTA through
resources provided by the Lab Support Facility, Mass Spec Facility, NMR facility,
and the Miba Machine Shop. We specifically thank Aikaterina Paraskevopoulou for
HRMS measurements and Jan Pecak for support with ICP-OES experi-ments. NMR facilities
at UW−Madison were supported by the NSF(CHE-1048642) and a generous gift from Paul
J. and Margaret M. Bender. Open Access funding provided by Institute of Science
and Technology Austria/KEMÖ. This study was supported by Austrian Science Fund (PAT
1250924), ACSGCI Pharmaceutical Roundtable, and National Science Foundation(CHE-2349003)
and (CHE-1048642).
article_number: e70417
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
full_name: Petrik, Adam
id: e273d403-329f-11ee-a353-8c34c056f8ed
last_name: Petrik
- first_name: Aleksander
full_name: Bena, Aleksander
id: 4197c39e-e8ec-11ed-86cb-afed934cd664
last_name: Bena
- first_name: Haralds
full_name: Baunis, Haralds
id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe
last_name: Baunis
- first_name: Riley M.
full_name: Kelch, Riley M.
last_name: Kelch
- first_name: Tehshik P.
full_name: Yoon, Tehshik P.
last_name: Yoon
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. Facile access to N-substituted
pyridyl ligands. Advanced Synthesis & Catalysis. 2026;368(9). doi:10.1002/adsc.70417
apa: Petrik, A., Bena, A., Baunis, H., Kelch, R. M., Yoon, T. P., & Pieber,
B. (2026). Facile access to N-substituted pyridyl ligands. Advanced Synthesis
& Catalysis. Wiley. https://doi.org/10.1002/adsc.70417
chicago: Petrik, Adam, Aleksander Bena, Haralds Baunis, Riley M. Kelch, Tehshik
P. Yoon, and Bartholomäus Pieber. “Facile Access to N-Substituted Pyridyl Ligands.”
Advanced Synthesis & Catalysis. Wiley, 2026. https://doi.org/10.1002/adsc.70417.
ieee: A. Petrik, A. Bena, H. Baunis, R. M. Kelch, T. P. Yoon, and B. Pieber, “Facile
access to N-substituted pyridyl ligands,” Advanced Synthesis & Catalysis,
vol. 368, no. 9. Wiley, 2026.
ista: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. 2026. Facile access
to N-substituted pyridyl ligands. Advanced Synthesis & Catalysis. 368(9),
e70417.
mla: Petrik, Adam, et al. “Facile Access to N-Substituted Pyridyl Ligands.” Advanced
Synthesis & Catalysis, vol. 368, no. 9, e70417, Wiley, 2026, doi:10.1002/adsc.70417.
short: A. Petrik, A. Bena, H. Baunis, R.M. Kelch, T.P. Yoon, B. Pieber, Advanced
Synthesis & Catalysis 368 (2026).
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-05-05T00:00:00Z
date_updated: 2026-05-07T07:33:33Z
day: '05'
ddc:
- '540'
department:
- _id: BaPi
- _id: GradSch
doi: 10.1002/adsc.70417
file:
- access_level: open_access
checksum: afe9752977898642c903abdc70b4a283
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T07:29:24Z
date_updated: 2026-05-07T07:29:24Z
file_id: '21833'
file_name: 2026_AdvSynthCatal_Petrik.pdf
file_size: 437184
relation: main_file
success: 1
file_date_updated: 2026-05-07T07:29:24Z
has_accepted_license: '1'
intvolume: ' 368'
issue: '9'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 8f1d607d-16d5-11f0-9cad-ab453295ba5e
grant_number: PAT 1250924
name: Photoactive ligands for transformative nickel catalysis
publication: Advanced Synthesis & Catalysis
publication_identifier:
eissn:
- 1615-4169
issn:
- 1615-4150
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Facile access to N-substituted pyridyl ligands
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 368
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21777'
abstract:
- lang: eng
text: The advantageous characteristics attributed to the 19F nucleus have made it
a popular target for nuclear magnetic resonance (NMR) once again in recent years.
Aside from solution NMR, an increasing number of studies have been conducted applying
solid-state magic-angle spinning (MAS) NMR to fluorine-labelled samples. Here,
the high chemical shift anisotropy and strong dipolar couplings can be utilised
to get structural insights into proteins and measure long distances. Despite increasing
popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR
often suffers from slow longitudinal T1 relaxation and therefore long recycle
delays. In this work, we expand paramagnetic doping, an approach commonly used
to reduce proton T1 relaxation times, to 19F-labelled biological samples. We study
the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F T1 and T2, and 13C T1 and T2 relaxation
in a [5-19F13C]-tryptophan-labelled protein via 19F-detected MAS NMR experiments.
The observed paramagnetic relaxation enhancement substantially reduces measurement
times of 19F MAS NMR experiments without compromising resolution. Additionally,
we report the chemical shift assignments of all four fluorotryptophan signals
in the 12×39 kDa-large protein TET2 using a mutagenesis approach.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: We thank Ben P. Tatman for insightful discussions. This research
was supported by the Scientific Service Units (SSUs) of ISTA through resources provided
by the Nuclear Magnetic Resonance Facility and the Lab Support Facility. We thank
Prof. Tobias Madl (Medical University Graz) for a sample of Omniscan. Lea M. Becker
is the recipient of a DOC fellowship of the Austrian Academy of Sciences at the
Institute of Science and Technology Austria (grant no. PR10660EAW01).
article_processing_charge: Yes
article_type: original
author:
- first_name: Lea Marie
full_name: Becker, Lea Marie
id: 36336939-eb97-11eb-a6c2-c83f1214ca79
last_name: Becker
orcid: 0000-0002-6401-5151
- first_name: Giorgia
full_name: Toscano, Giorgia
id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
last_name: Toscano
- first_name: Anna
full_name: Kapitonova, Anna
id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
last_name: Kapitonova
- first_name: Rajkumar
full_name: Singh, Rajkumar
id: a3089acd-6806-11ee-bacc-f0c7d500ad20
last_name: Singh
- first_name: Undina
full_name: Guillerm, Undina
id: bb74f472-ae54-11eb-9835-bc9c22fb1183
last_name: Guillerm
- first_name: Roman J.
full_name: Lichtenecker, Roman J.
last_name: Lichtenecker
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: Becker LM, Toscano G, Kapitonova A, et al. Accelerated 19F biomolecular magic-angle
spinning NMR with paramagnetic dopants. Magnetic Resonance. 2026;7(1):29-37.
doi:10.5194/mr-7-29-2026
apa: Becker, L. M., Toscano, G., Kapitonova, A., Singh, R., Guillerm, U., Lichtenecker,
R. J., & Schanda, P. (2026). Accelerated 19F biomolecular magic-angle spinning
NMR with paramagnetic dopants. Magnetic Resonance. Copernicus Publications.
https://doi.org/10.5194/mr-7-29-2026
chicago: Becker, Lea Marie, Giorgia Toscano, Anna Kapitonova, Rajkumar Singh, Undina
Guillerm, Roman J. Lichtenecker, and Paul Schanda. “Accelerated 19F Biomolecular
Magic-Angle Spinning NMR with Paramagnetic Dopants.” Magnetic Resonance.
Copernicus Publications, 2026. https://doi.org/10.5194/mr-7-29-2026.
ieee: L. M. Becker et al., “Accelerated 19F biomolecular magic-angle spinning
NMR with paramagnetic dopants,” Magnetic Resonance, vol. 7, no. 1. Copernicus
Publications, pp. 29–37, 2026.
ista: Becker LM, Toscano G, Kapitonova A, Singh R, Guillerm U, Lichtenecker RJ,
Schanda P. 2026. Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic
dopants. Magnetic Resonance. 7(1), 29–37.
mla: Becker, Lea Marie, et al. “Accelerated 19F Biomolecular Magic-Angle Spinning
NMR with Paramagnetic Dopants.” Magnetic Resonance, vol. 7, no. 1, Copernicus
Publications, 2026, pp. 29–37, doi:10.5194/mr-7-29-2026.
short: L.M. Becker, G. Toscano, A. Kapitonova, R. Singh, U. Guillerm, R.J. Lichtenecker,
P. Schanda, Magnetic Resonance 7 (2026) 29–37.
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:49:59Z
day: '16'
ddc:
- '540'
department:
- _id: PaSc
- _id: GradSch
doi: 10.5194/mr-7-29-2026
external_id:
pmid:
- '42057802'
has_accepted_license: '1'
intvolume: ' 7'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/mr-7-29-2026
month: '04'
oa: 1
oa_version: Published Version
page: 29-37
pmid: 1
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
- _id: 7be609c4-9f16-11ee-852c-85015ce2b9b0
grant_number: '26777'
name: Exploring protein dynamics by solid-state MAS NMR through specific labeling
approaches
publication: Magnetic Resonance
publication_identifier:
eissn:
- 2699-0016
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21778'
abstract:
- lang: eng
text: "We prove that every \U0001D43F-bilipschitz mapping ℤ 2 → ℝ2 canbe extended
to a \U0001D436(\U0001D43F)-bilipschitz mapping ℝ2 → ℝ2,and we provide a polynomial
upper bound for \U0001D436(\U0001D43F).Moreover, we extend the result to every
separated netin ℝ2 instead of ℤ 2, with the upper bound gaininga polynomial dependence
on the separation and netconstants associated to the given separated net. Thisanswers
an Oberwolfach question of Navas from 2015and is also a positive solution of the
two-dimensionalform of a decades old open (in all dimensions at leasttwo) problem
due to Alestalo Trotsenko and Väisälä."
acknowledgement: The authors wish to thank Professor Leonid Kovalev for a valuable
observation on the first versionof this work, which led to improved estimates and
cleaner proofs in Section 6. The present workdeveloped from a research visit of
Michael Dymond to Vojtěch Kaluža at IST Austria, funded by aLondon Mathematical
Society Research in Pairs grant. This work was done whilst Vojtěch Kalužawas fully
funded by the Austria Science Fund (FWF) [M 3100-N].
article_number: e70540
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
full_name: Dymond, Michael
last_name: Dymond
- first_name: Vojtech
full_name: Kaluza, Vojtech
id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
last_name: Kaluza
orcid: 0000-0002-2512-8698
citation:
ama: Dymond M, Kaluza V. Planar bilipschitz extension from separated nets. Journal
of the London Mathematical Society. 2026;113(4). doi:10.1112/jlms.70540
apa: Dymond, M., & Kaluza, V. (2026). Planar bilipschitz extension from separated
nets. Journal of the London Mathematical Society. Wiley. https://doi.org/10.1112/jlms.70540
chicago: Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from
Separated Nets.” Journal of the London Mathematical Society. Wiley, 2026.
https://doi.org/10.1112/jlms.70540.
ieee: M. Dymond and V. Kaluza, “Planar bilipschitz extension from separated nets,”
Journal of the London Mathematical Society, vol. 113, no. 4. Wiley, 2026.
ista: Dymond M, Kaluza V. 2026. Planar bilipschitz extension from separated nets.
Journal of the London Mathematical Society. 113(4), e70540.
mla: Dymond, Michael, and Vojtech Kaluza. “Planar Bilipschitz Extension from Separated
Nets.” Journal of the London Mathematical Society, vol. 113, no. 4, e70540,
Wiley, 2026, doi:10.1112/jlms.70540.
short: M. Dymond, V. Kaluza, Journal of the London Mathematical Society 113 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T08:29:18Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1112/jlms.70540
external_id:
arxiv:
- '2410.22294'
file:
- access_level: open_access
checksum: 6dbfc7134f732d17c5c8467843a73e90
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T08:27:43Z
date_updated: 2026-05-07T08:27:43Z
file_id: '21836'
file_name: 2026_JourLondonMathSoc_Dymond.pdf
file_size: 617569
relation: main_file
success: 1
file_date_updated: 2026-05-07T08:27:43Z
has_accepted_license: '1'
intvolume: ' 113'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: fc35eaa2-9c52-11eb-aca3-88501ab155e9
grant_number: M03100
name: Spectra and topology of graphs and of simplicial complexes
publication: Journal of the London Mathematical Society
publication_identifier:
eissn:
- 1469-7750
issn:
- 0024-6107
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Planar bilipschitz extension from separated nets
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 113
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21779'
abstract:
- lang: eng
text: Acidomycin is an anti-mycobacterial antibiotic with a unique mode of action,
targeting the biotin biosynthesis pathway. Despite being highly active against
mycobacteria in vitro, its development as an anti-tubercular agent has been hindered
due to suboptimal pharmacokinetics. Engineering of the acidomycin biosynthesis
may yield new analogues with improved pharmacological properties. Here, we describe
the identification of the acidomycin biosynthetic gene cluster (BGC) in a Streptomyces
bacterium isolated from the rhizosphere of Edelweiss. Notably, the acidomycin
BGC is located in proximity to the genes for the biosynthesis of stravidins, secondary
metabolites targeting a different enzyme in the biotin biosynthesis pathway, and
two genes for streptavidins, proteins that strongly bind and sequester biotin.
The identity of the acidomycin BGC was confirmed via both gene knock-out and heterologous
expression, which suggested that the fatty acid required for the formation of
acidomycin's acyl chain is most likely scavenged from the biotin biosynthesis
pathway. CRISPR/Cas9-assisted knock-out of the cytochrome P450-encoding gene in
the acidomycin BGC resulted in a significant decrease in its yield but did not
abrogate the biosynthesis completely.
acknowledgement: This work was supported by the University of Vienna. The authors
thank Anna Fabisikova from the Mass Spectrometry Centre and the team of the NMR
Centre (both of the Faculty of Chemistry, University of Vienna and members of the
Vienna Life Science Instruments) for assistance with data acquisition. Open Access
funding provided by Universitat Wien. This work was supported by Universität Wien.
article_number: e70357
article_processing_charge: Yes
article_type: original
author:
- first_name: Anna
full_name: Vignolle, Anna
last_name: Vignolle
- first_name: Martin
full_name: Zehl, Martin
id: 8e016d5b-5d77-11f0-86d2-96cdb3922a55
last_name: Zehl
orcid: 0000-0001-9685-0373
- first_name: Jaime Felipe Guerrero
full_name: Garzón, Jaime Felipe Guerrero
last_name: Garzón
- first_name: Olha
full_name: Schneider, Olha
last_name: Schneider
- first_name: Johannes
full_name: Gafriller, Johannes
last_name: Gafriller
- first_name: Ulrike
full_name: Grienke, Ulrike
last_name: Grienke
- first_name: Rasmus H.
full_name: Kirkegaard, Rasmus H.
last_name: Kirkegaard
- first_name: Sergey B.
full_name: Zotchev, Sergey B.
last_name: Zotchev
citation:
ama: Vignolle A, Zehl M, Garzón JFG, et al. Identification and characterisation
of the gene cluster governing biosynthesis of the anti-mycobacterial antibiotic
acidomycin. Microbial Biotechnology. 2026;19(4). doi:10.1111/1751-7915.70357
apa: Vignolle, A., Zehl, M., Garzón, J. F. G., Schneider, O., Gafriller, J., Grienke,
U., … Zotchev, S. B. (2026). Identification and characterisation of the gene cluster
governing biosynthesis of the anti-mycobacterial antibiotic acidomycin. Microbial
Biotechnology. Wiley. https://doi.org/10.1111/1751-7915.70357
chicago: Vignolle, Anna, Martin Zehl, Jaime Felipe Guerrero Garzón, Olha Schneider,
Johannes Gafriller, Ulrike Grienke, Rasmus H. Kirkegaard, and Sergey B. Zotchev.
“Identification and Characterisation of the Gene Cluster Governing Biosynthesis
of the Anti-Mycobacterial Antibiotic Acidomycin.” Microbial Biotechnology.
Wiley, 2026. https://doi.org/10.1111/1751-7915.70357.
ieee: A. Vignolle et al., “Identification and characterisation of the gene
cluster governing biosynthesis of the anti-mycobacterial antibiotic acidomycin,”
Microbial Biotechnology, vol. 19, no. 4. Wiley, 2026.
ista: Vignolle A, Zehl M, Garzón JFG, Schneider O, Gafriller J, Grienke U, Kirkegaard
RH, Zotchev SB. 2026. Identification and characterisation of the gene cluster
governing biosynthesis of the anti-mycobacterial antibiotic acidomycin. Microbial
Biotechnology. 19(4), e70357.
mla: Vignolle, Anna, et al. “Identification and Characterisation of the Gene Cluster
Governing Biosynthesis of the Anti-Mycobacterial Antibiotic Acidomycin.” Microbial
Biotechnology, vol. 19, no. 4, e70357, Wiley, 2026, doi:10.1111/1751-7915.70357.
short: A. Vignolle, M. Zehl, J.F.G. Garzón, O. Schneider, J. Gafriller, U. Grienke,
R.H. Kirkegaard, S.B. Zotchev, Microbial Biotechnology 19 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T08:22:41Z
day: '01'
ddc:
- '570'
department:
- _id: MassSpec
doi: 10.1111/1751-7915.70357
external_id:
pmid:
- '42036976'
file:
- access_level: open_access
checksum: 8c8aa660cef5394167e06f187adbabf0
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T08:21:06Z
date_updated: 2026-05-07T08:21:06Z
file_id: '21835'
file_name: 2026_MicrobialBiotechnology_Vignolle.pdf
file_size: 575492
relation: main_file
success: 1
file_date_updated: 2026-05-07T08:21:06Z
has_accepted_license: '1'
intvolume: ' 19'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Microbial Biotechnology
publication_identifier:
eissn:
- 1751-7915
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Identification and characterisation of the gene cluster governing biosynthesis
of the anti-mycobacterial antibiotic acidomycin
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21780'
abstract:
- lang: eng
text: It is predicted that half or more of all cataclysmic variables (CVs) should
have evolved past the period minimum and now exist as so-called period bouncers
where a white dwarf should be accreting from a Roche lobe filling substellar companion.
However, this prediction stands in stark contrast to observations, where only
a few per cent of CVs are found in this evolutionary phase. A potential solution
to this discrepancy is that a magnetic field emerges from within the white dwarf
after the system has reached the period minimum. The transfer of angular momentum
from the spin of the white dwarf into the orbit then pushes the two stars apart,
detaching them for potentially billions of years. Here we present the discovery
of ZTF J021804.16+071152.93, a detached 0.69 +- 0.01 M, 19 MG magnetic white
dwarf plus 37 +- 5MJup brown dwarf binary with an orbital period of 1.7 h. The
kinematics of the system indicate that it is a high probability member of the
Galactic thick disc. However, this strongly disagrees with the much younger age
of the system obtained from the white dwarf parameters, implying that the system
may have been accreting in the past. This system is therefore consistent with
having detached as a result of the emergence of the magnetic field of the white
dwarf when the system was still mass transferring, and may represent the ultimate
fate for many (perhaps even most) CVs.
acknowledgement: "The results presented in this paper are based on observations collected
at the European Southern Observatory under programme IDs 113.D-0277 and 114.D-0066
and on observations made with the Gran Telescopio Canarias (programme ID GTC119-23B),
installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto
de Astrofísica de Canarias, on the island of La Palma.\r\n\r\nSGP acknowledges support
by the Science and Technology Facilities Council (grant ST/B001174/1). ARM acknowledges
support from MINECO under the PID2023-148661NB-I00 grant and by the AGAUR/Generalitat
de Catalunya grant SGR-386/2021. RMO was funded by INTA through grant PRE-OBSERVATORIO
and acknowledges support from project PID2023-146210NB-I00 funded by MICIU/AEI/10.13039/501100011033
and by ERDF/EU. MZ acknowledges support from FONDECYT (grants 1250525 and 1221059).
VSD and HiPERCAM were funded by the Science and Technology Facilities Council (grant
ST/Z000033/1). MRS thanks for support from FONDECYT (grant No. 1221059). This project
received funding from the European Research Council under the European Union’s Horizon
2020 research and innovation programme (Grant agreement numbers 101002408-MOS100PC)."
article_number: stag521
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: S. G.
full_name: Parsons, S. G.
last_name: Parsons
- first_name: A. J.
full_name: Brown, A. J.
last_name: Brown
- first_name: S. L.
full_name: Casewell, S. L.
last_name: Casewell
- first_name: S. P.
full_name: Littlefair, S. P.
last_name: Littlefair
- first_name: Joannes C
full_name: van Roestel, Joannes C
id: 4d122fc8-6083-11f0-87a5-97d68b860333
last_name: van Roestel
- first_name: A.
full_name: Rebassa-Mansergas, A.
last_name: Rebassa-Mansergas
- first_name: R.
full_name: Murillo-Ojeda, R.
last_name: Murillo-Ojeda
- first_name: M.
full_name: Zorotovic, M.
last_name: Zorotovic
- first_name: M. R.
full_name: Schreiber, M. R.
last_name: Schreiber
- first_name: S.
full_name: Bagnulo, S.
last_name: Bagnulo
- first_name: M. A.
full_name: Stroet, M. A.
last_name: Stroet
- first_name: N.
full_name: Castro Segura, N.
last_name: Castro Segura
- first_name: V. S.
full_name: Dhillon, V. S.
last_name: Dhillon
- first_name: M. J.
full_name: Dyer, M. J.
last_name: Dyer
- first_name: J. A.
full_name: Garbutt, J. A.
last_name: Garbutt
- first_name: M. J.
full_name: Green, M. J.
last_name: Green
- first_name: D.
full_name: Jarvis, D.
last_name: Jarvis
- first_name: M. R.
full_name: Kennedy, M. R.
last_name: Kennedy
- first_name: P.
full_name: Kerry, P.
last_name: Kerry
- first_name: J.
full_name: Mccormac, J.
last_name: Mccormac
- first_name: J.
full_name: Munday, J.
last_name: Munday
- first_name: I.
full_name: Pelisoli, I.
last_name: Pelisoli
- first_name: E.
full_name: Pike, E.
last_name: Pike
- first_name: D. I.
full_name: Sahman, D. I.
last_name: Sahman
- first_name: A.
full_name: Yates, A.
last_name: Yates
citation:
ama: 'Parsons SG, Brown AJ, Casewell SL, et al. ZTF J021804.16+071152.93: A dead
cataclysmic variable and potential solution to the missing period bouncer cataclysmic
variables. Monthly Notices of the Royal Astronomical Society. 2026;547(4).
doi:10.1093/mnras/stag521'
apa: 'Parsons, S. G., Brown, A. J., Casewell, S. L., Littlefair, S. P., van Roestel,
J. C., Rebassa-Mansergas, A., … Yates, A. (2026). ZTF J021804.16+071152.93: A
dead cataclysmic variable and potential solution to the missing period bouncer
cataclysmic variables. Monthly Notices of the Royal Astronomical Society.
Oxford University Press. https://doi.org/10.1093/mnras/stag521'
chicago: 'Parsons, S. G., A. J. Brown, S. L. Casewell, S. P. Littlefair, Joannes
C van Roestel, A. Rebassa-Mansergas, R. Murillo-Ojeda, et al. “ZTF J021804.16+071152.93:
A Dead Cataclysmic Variable and Potential Solution to the Missing Period Bouncer
Cataclysmic Variables.” Monthly Notices of the Royal Astronomical Society.
Oxford University Press, 2026. https://doi.org/10.1093/mnras/stag521.'
ieee: 'S. G. Parsons et al., “ZTF J021804.16+071152.93: A dead cataclysmic
variable and potential solution to the missing period bouncer cataclysmic variables,”
Monthly Notices of the Royal Astronomical Society, vol. 547, no. 4. Oxford
University Press, 2026.'
ista: 'Parsons SG, Brown AJ, Casewell SL, Littlefair SP, van Roestel JC, Rebassa-Mansergas
A, Murillo-Ojeda R, Zorotovic M, Schreiber MR, Bagnulo S, Stroet MA, Castro Segura
N, Dhillon VS, Dyer MJ, Garbutt JA, Green MJ, Jarvis D, Kennedy MR, Kerry P, Mccormac
J, Munday J, Pelisoli I, Pike E, Sahman DI, Yates A. 2026. ZTF J021804.16+071152.93:
A dead cataclysmic variable and potential solution to the missing period bouncer
cataclysmic variables. Monthly Notices of the Royal Astronomical Society. 547(4),
stag521.'
mla: 'Parsons, S. G., et al. “ZTF J021804.16+071152.93: A Dead Cataclysmic Variable
and Potential Solution to the Missing Period Bouncer Cataclysmic Variables.” Monthly
Notices of the Royal Astronomical Society, vol. 547, no. 4, stag521, Oxford
University Press, 2026, doi:10.1093/mnras/stag521.'
short: S.G. Parsons, A.J. Brown, S.L. Casewell, S.P. Littlefair, J.C. van Roestel,
A. Rebassa-Mansergas, R. Murillo-Ojeda, M. Zorotovic, M.R. Schreiber, S. Bagnulo,
M.A. Stroet, N. Castro Segura, V.S. Dhillon, M.J. Dyer, J.A. Garbutt, M.J. Green,
D. Jarvis, M.R. Kennedy, P. Kerry, J. Mccormac, J. Munday, I. Pelisoli, E. Pike,
D.I. Sahman, A. Yates, Monthly Notices of the Royal Astronomical Society 547 (2026).
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-07T07:51:58Z
day: '01'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1093/mnras/stag521
external_id:
arxiv:
- '2603.12888'
file:
- access_level: open_access
checksum: a64094199db4dedb12fc121b7c65fe97
content_type: application/pdf
creator: dernst
date_created: 2026-05-07T07:51:06Z
date_updated: 2026-05-07T07:51:06Z
file_id: '21834'
file_name: 2026_MNRAS_Parsons.pdf
file_size: 5955512
relation: main_file
success: 1
file_date_updated: 2026-05-07T07:51:06Z
has_accepted_license: '1'
intvolume: ' 547'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'ZTF J021804.16+071152.93: A dead cataclysmic variable and potential solution
to the missing period bouncer cataclysmic variables'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 547
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21781'
abstract:
- lang: eng
text: "Given a set A of n points (vertices) in general position in the plane, the
complete geometric graph \r\nKn[A] consists of all (n2) segments (edges) between
the elements of A. It is known that the edge set of every complete geometric graph
on n vertices can be partitioned into O(n3∕2) crossing-free paths (or matchings).
We strengthen this result under various additional assumptions on the point set.
In particular, we prove that for a set A of n randomly selected points, uniformly
distributed in [0,1]2, with probability tending to 1 as n→∞, the edge set of Kn[A]
can be covered by O(nlogn) crossing-free paths and by O(n√logn) crossing-free
matchings. On the other hand, we construct n-element point sets such that covering
the edge set of Kn[A] requires a quadratic number of monotone paths."
acknowledgement: "Research partially supported by ERC Advanced Grant \"GeoScape\",
no. 882971 and\r\nHungarian NKFIH grant no. K-131529. Work by the third author is
supported by EPSRC grant\r\nEP/X013642/1. Work by the third author is partially
supported by the European Research Council (ERC), grant no. 788183, and by the Wittgenstein
Prize, Austrian Science Fund (FWF), grant no. Z 342-N31."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Adrian
full_name: Dumitrescu, Adrian
last_name: Dumitrescu
- first_name: János
full_name: Pach, János
last_name: Pach
- first_name: Morteza
full_name: Saghafian, Morteza
id: f86f7148-b140-11ec-9577-95435b8df824
last_name: Saghafian
- first_name: Alex
full_name: Scott, Alex
last_name: Scott
citation:
ama: Dumitrescu A, Pach J, Saghafian M, Scott A. Covering complete geometric graphs
by monotone paths. Combinatorics and Number Theory. 2026;15(1):73-82. doi:10.2140/cnt.2026.15.73
apa: Dumitrescu, A., Pach, J., Saghafian, M., & Scott, A. (2026). Covering complete
geometric graphs by monotone paths. Combinatorics and Number Theory. Mathematical
Sciences Publishers. https://doi.org/10.2140/cnt.2026.15.73
chicago: Dumitrescu, Adrian, János Pach, Morteza Saghafian, and Alex Scott. “Covering
Complete Geometric Graphs by Monotone Paths.” Combinatorics and Number Theory.
Mathematical Sciences Publishers, 2026. https://doi.org/10.2140/cnt.2026.15.73.
ieee: A. Dumitrescu, J. Pach, M. Saghafian, and A. Scott, “Covering complete geometric
graphs by monotone paths,” Combinatorics and Number Theory, vol. 15, no.
1. Mathematical Sciences Publishers, pp. 73–82, 2026.
ista: Dumitrescu A, Pach J, Saghafian M, Scott A. 2026. Covering complete geometric
graphs by monotone paths. Combinatorics and Number Theory. 15(1), 73–82.
mla: Dumitrescu, Adrian, et al. “Covering Complete Geometric Graphs by Monotone
Paths.” Combinatorics and Number Theory, vol. 15, no. 1, Mathematical Sciences
Publishers, 2026, pp. 73–82, doi:10.2140/cnt.2026.15.73.
short: A. Dumitrescu, J. Pach, M. Saghafian, A. Scott, Combinatorics and Number
Theory 15 (2026) 73–82.
date_created: 2026-05-03T22:01:37Z
date_published: 2026-04-17T00:00:00Z
date_updated: 2026-05-07T07:45:24Z
day: '17'
department:
- _id: HeEd
doi: 10.2140/cnt.2026.15.73
ec_funded: 1
external_id:
arxiv:
- '2507.10840'
intvolume: ' 15'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2507.10840
month: '04'
oa: 1
oa_version: Preprint
page: 73-82
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
publication: Combinatorics and Number Theory
publication_identifier:
eissn:
- 2996-220X
issn:
- 2996-2196
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Covering complete geometric graphs by monotone paths
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21798'
abstract:
- lang: eng
text: 'Phase singularities—points carrying quantized topological charge—are universal
features found across diverse wave systems from superfluids and superconductors
to acoustic and optical fields1,2,3,4. Ensembles of these singularities exhibit
distance correlations resembling particles in liquids5,6,7,8, extensively studied
for their role in exotic material phases9,10,11. By contrast, the full correlations
in phase space that govern the system evolution have remained unexplored and experimentally
inaccessible. Here we directly measure the ultrafast dynamics of optical singularity
ensembles, capturing their full phase-space correlations, presenting the joint
distance–velocity distribution. Our observations show a breakdown of the particle-singularity
analogy12: phase singularities accelerate towards formally divergent velocities
in the moment before annihilation7,13,14, indicated by measurements of velocities
exceeding the speed of light. These apparent superluminal velocities are paradoxically
amplified by the slow group velocity of hyperbolic phonon polaritons in our material
platform, hexagonal boron nitride membranes15,16,17,18,19. We demonstrate these
phenomena using combined hardware and algorithmic advances in ultrafast electron
microscopy18,20,21,22,23,24,25, achieving spatial and temporal resolutions, each
an order of magnitude below the polaritonic wavelength and cycle period. Our findings
deepen our understanding of phase singularities and their universality, enabling
to probe topological defect dynamics at previously unattainable timescales.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: T.
full_name: Bucher, T.
last_name: Bucher
- first_name: A.
full_name: Gorlach, A.
last_name: Gorlach
- first_name: A.
full_name: Niedermayr, A.
last_name: Niedermayr
- first_name: Q.
full_name: Yan, Q.
last_name: Yan
- first_name: H.
full_name: Nahari, H.
last_name: Nahari
- first_name: K.
full_name: Wang, K.
last_name: Wang
- first_name: R.
full_name: Ruimy, R.
last_name: Ruimy
- first_name: Y.
full_name: Adiv, Y.
last_name: Adiv
- first_name: M.
full_name: Yannai, M.
last_name: Yannai
- first_name: T. L.
full_name: Abudi, T. L.
last_name: Abudi
- first_name: E.
full_name: Janzen, E.
last_name: Janzen
- first_name: C.
full_name: Spaegele, C.
last_name: Spaegele
- first_name: Charles
full_name: Roques-Carmes, Charles
id: e2e68fc9-6505-11ef-a541-eb4e72cc3e82
last_name: Roques-Carmes
- first_name: J. H.
full_name: Edgar, J. H.
last_name: Edgar
- first_name: F. H. L.
full_name: Koppens, F. H. L.
last_name: Koppens
- first_name: G. M.
full_name: Vanacore, G. M.
last_name: Vanacore
- first_name: H.
full_name: H. Sheinfux, H.
last_name: H. Sheinfux
- first_name: S.
full_name: Tsesses, S.
last_name: Tsesses
- first_name: I.
full_name: Kaminer, I.
last_name: Kaminer
citation:
ama: Bucher T, Gorlach A, Niedermayr A, et al. Superluminal correlations in ensembles
of optical phase singularities. Nature. 2026;651(8107):920-926. doi:10.1038/s41586-026-10209-z
apa: Bucher, T., Gorlach, A., Niedermayr, A., Yan, Q., Nahari, H., Wang, K., … Kaminer,
I. (2026). Superluminal correlations in ensembles of optical phase singularities.
Nature. Springer Nature. https://doi.org/10.1038/s41586-026-10209-z
chicago: Bucher, T., A. Gorlach, A. Niedermayr, Q. Yan, H. Nahari, K. Wang, R. Ruimy,
et al. “Superluminal Correlations in Ensembles of Optical Phase Singularities.”
Nature. Springer Nature, 2026. https://doi.org/10.1038/s41586-026-10209-z.
ieee: T. Bucher et al., “Superluminal correlations in ensembles of optical
phase singularities,” Nature, vol. 651, no. 8107. Springer Nature, pp.
920–926, 2026.
ista: Bucher T, Gorlach A, Niedermayr A, Yan Q, Nahari H, Wang K, Ruimy R, Adiv
Y, Yannai M, Abudi TL, Janzen E, Spaegele C, Roques-Carmes C, Edgar JH, Koppens
FHL, Vanacore GM, H. Sheinfux H, Tsesses S, Kaminer I. 2026. Superluminal correlations
in ensembles of optical phase singularities. Nature. 651(8107), 920–926.
mla: Bucher, T., et al. “Superluminal Correlations in Ensembles of Optical Phase
Singularities.” Nature, vol. 651, no. 8107, Springer Nature, 2026, pp.
920–26, doi:10.1038/s41586-026-10209-z.
short: T. Bucher, A. Gorlach, A. Niedermayr, Q. Yan, H. Nahari, K. Wang, R. Ruimy,
Y. Adiv, M. Yannai, T.L. Abudi, E. Janzen, C. Spaegele, C. Roques-Carmes, J.H.
Edgar, F.H.L. Koppens, G.M. Vanacore, H. H. Sheinfux, S. Tsesses, I. Kaminer,
Nature 651 (2026) 920–926.
date_created: 2026-05-05T11:05:31Z
date_published: 2026-03-25T00:00:00Z
date_updated: 2026-05-05T11:10:07Z
day: '25'
doi: 10.1038/s41586-026-10209-z
extern: '1'
external_id:
arxiv:
- '2509.17675'
intvolume: ' 651'
issue: '8107'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2509.17675
month: '03'
oa: 1
oa_version: Preprint
page: 920-926
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Superluminal correlations in ensembles of optical phase singularities
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 651
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21800'
abstract:
- lang: eng
text: 'LAMMPS input scripts to simulate toroidal vesicles composed of pure bolalipid
membranes and archaeal mixture membranes for the following publication: "Cracking
donuts and sorting lipids: geometry controls archaeal membrane stability and lipid
organization" by Felix Frey, Miguel Amaral, and Andela Saric.'
article_processing_charge: No
author:
- first_name: Felix F
full_name: Frey, Felix F
id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3
last_name: Frey
orcid: 0000-0001-8501-6017
- first_name: Miguel
full_name: Santana de Freitas Amaral, Miguel
id: 4f2d02dd-47a9-11ec-ad10-82820ed3f501
last_name: Santana de Freitas Amaral
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: 'Frey FF, Santana de Freitas Amaral M, Šarić A. Cracking donuts and sorting
lipids: Geometry controls archaeal membrane stability and lipid organization.
2026. doi:10.5281/ZENODO.18772086'
apa: 'Frey, F. F., Santana de Freitas Amaral, M., & Šarić, A. (2026). Cracking
donuts and sorting lipids: Geometry controls archaeal membrane stability and lipid
organization. Zenodo. https://doi.org/10.5281/ZENODO.18772086'
chicago: 'Frey, Felix F, Miguel Santana de Freitas Amaral, and Anđela Šarić. “Cracking
Donuts and Sorting Lipids: Geometry Controls Archaeal Membrane Stability and Lipid
Organization.” Zenodo, 2026. https://doi.org/10.5281/ZENODO.18772086.'
ieee: 'F. F. Frey, M. Santana de Freitas Amaral, and A. Šarić, “Cracking donuts
and sorting lipids: Geometry controls archaeal membrane stability and lipid organization.”
Zenodo, 2026.'
ista: 'Frey FF, Santana de Freitas Amaral M, Šarić A. 2026. Cracking donuts and
sorting lipids: Geometry controls archaeal membrane stability and lipid organization,
Zenodo, 10.5281/ZENODO.18772086.'
mla: 'Frey, Felix F., et al. Cracking Donuts and Sorting Lipids: Geometry Controls
Archaeal Membrane Stability and Lipid Organization. Zenodo, 2026, doi:10.5281/ZENODO.18772086.'
short: F.F. Frey, M. Santana de Freitas Amaral, A. Šarić, (2026).
corr_author: '1'
date_created: 2026-05-05T12:11:52Z
date_published: 2026-02-25T00:00:00Z
date_updated: 2026-05-05T12:40:41Z
day: '25'
ddc:
- '540'
department:
- _id: AnSa
doi: 10.5281/ZENODO.18772086
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/ZENODO.18772086
month: '02'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '21748'
relation: used_in_publication
status: public
status: public
title: 'Cracking donuts and sorting lipids: Geometry controls archaeal membrane stability
and lipid organization'
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21837'
abstract:
- lang: eng
text: 'In a warming world of glacier changes, the scientific community has dedicated
increasing attention to debris-covered glaciers and their response to climate.
A variety of models with distinct complexity and data requirements have been developed
and widely used to simulate melt under debris at different sites and scales, but
their skills have never been compared. As part of the activities of the International
Association of Cryospheric Sciences (IACS) Debris Covered Glacier Working Group,
we present an intercomparison exercise aimed at advancing our understanding of
model skills in simulating ice melt under a debris layer. We compare 15 models
with different complexity at nine sites in the European Alps, Caucasus, Chilean
Andes, Nepalese Himalaya and the Southern Alps of New Zealand, over one melt season.
We run the models with measured meteorological data from automatic weather stations
and estimated or measured debris properties. We consider four main model categories:
(i) energy balance models that calculate melt by solving the physics of heat transfer
to the debris layer, but require a high amount of input data; (ii) a simplified
energy balance model; (iii) enhanced temperature-index models; and (iv) simple
empirical temperature-index models that have been extensively used given their
low data requirement but require calibration of their empirical parameters. Model
performance is evaluated using on-site measurements of sub-debris melt (for all
models) and surface temperature (for models based on the surface energy balance).
Our results show that physically-based energy balance models and empirical temperature-index
models perform in a distinct manner. At one end of the spectrum, simple temperature-index
models are accurate when recalibrated or when using site-specific literature parameters,
and show poor results when parameters are uncalibrated. At the other end, energy
balance models show a range of performance: the most accurate energy balance models
are those with the highest degree of complexity at the atmosphere-debris interface.
An important data gap emerged from our experiment: the poor performance of all
models at three sites was related to the poor knowledge of debris properties,
and specifically of thermal conductivity. Future work should focus on both: (i) consistent
data acquisition to evaluate existing models and support new model developments;
(ii) advancing models by accounting for processes such as debris-snow interactions,
moisture in the debris and refreezing. We suggest that a systematic effort of
model development using a common model framework could be carried out in phase
II of the Working Group.'
acknowledgement: "This project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
grant agreement No\r\n772751, RAVEN, “Rapid mass losses of debris covered glaciers
in\r\nHigh Mountain Asia”. It was also supported by the SNSF RENOIR\r\nproject “Resolving
the thickness of debris on Earth’s glaciers and\r\nits rate of change (RENOIR)”,
project number 204322.\r\nDavid Rounce received support from NASA-ROSES program\r\ngrants
NNX17AB27G and 80NSSC17K0566. Walter Immerzeel\r\nand Jakob Steiner acknowledge
support from the European Research Council (ERC) under the European Union’s Horizon
2020\r\nresearch and innovation program (grant agreement no. 676819).\r\nBen Brock
acknowledges support from the EU/FP7 ACQWA\r\n(Assessing Climate impacts on the
Quantity and quality of WAter) project, NERC grant NE/C514282/1, the British Council-Italian\r\nMinistry
of University and Research Partnership programme and\r\nthe Carnegie Trust for the
Universities of Scotland.\r\nThe authors acknowledge the International Association
of\r\nCryospheric Sciences (IACS) for supporting the creation of the\r\nDebris-Covered
Glaciers Working Group (DCG-WG) which enabled this model intercomparison experiment.\r\nThe
authors thank Martin Heynen for producing Figs. 3 and 4.\r\nThe authors thank Duncan
Quincey and Richard Essery for their\r\nconstructive feedback and comments.\r\n"
article_processing_charge: Yes
article_type: original
author:
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
orcid: 0000-0002-5554-8087
- first_name: Adrià
full_name: Fontrodona-Bach, Adrià
id: f06891fd-9f42-11ee-8632-a20971c43046
last_name: Fontrodona-Bach
- first_name: David R.
full_name: Rounce, David R.
last_name: Rounce
- first_name: Catriona Louise
full_name: Fyffe, Catriona Louise
id: 001b0422-8d15-11ed-bc51-cab6c037a228
last_name: Fyffe
- first_name: Leif S.
full_name: Anderson, Leif S.
last_name: Anderson
- first_name: Álvaro
full_name: Ayala, Álvaro
last_name: Ayala
- first_name: Ben W.
full_name: Brock, Ben W.
last_name: Brock
- first_name: Pascal
full_name: Buri, Pascal
last_name: Buri
- first_name: Stefan
full_name: Fugger, Stefan
last_name: Fugger
- first_name: Koji
full_name: Fujita, Koji
last_name: Fujita
- first_name: PRATEEK
full_name: GANTAYAT, PRATEEK
id: 02734268-3e8d-11ef-80a1-cec4a088d004
last_name: GANTAYAT
- first_name: Alexander R.
full_name: Groos, Alexander R.
last_name: Groos
- first_name: Walter
full_name: Immerzeel, Walter
last_name: Immerzeel
- first_name: Marin
full_name: Kneib, Marin
last_name: Kneib
- first_name: Christoph
full_name: Mayer, Christoph
last_name: Mayer
- first_name: Shelley
full_name: MacDonell, Shelley
last_name: MacDonell
- first_name: Michael
full_name: McCarthy, Michael
id: 22a2674a-61ce-11ee-94b5-d18813baf16f
last_name: McCarthy
- first_name: James
full_name: McPhee, James
last_name: McPhee
- first_name: Evan
full_name: Miles, Evan
last_name: Miles
- first_name: Heather
full_name: Purdie, Heather
last_name: Purdie
- first_name: Ekaterina
full_name: Rets, Ekaterina
last_name: Rets
- first_name: Akiko
full_name: Sakai, Akiko
last_name: Sakai
- first_name: Thomas
full_name: Shaw, Thomas
id: 3caa3f91-1f03-11ee-96ce-e0e553054d6e
last_name: Shaw
orcid: 0000-0001-7640-6152
- first_name: Jakob
full_name: Steiner, Jakob
last_name: Steiner
- first_name: Patrick
full_name: Wagnon, Patrick
last_name: Wagnon
- first_name: Alex
full_name: Winter-Billington, Alex
last_name: Winter-Billington
citation:
ama: 'Pellicciotti F, Fontrodona-Bach A, Rounce DR, et al. DCG-MIP: The debris-covered
glacier melt model intercomparison experiment. The Cryosphere. 2026;20(3):1895-1928.
doi:10.5194/tc-20-1895-2026'
apa: 'Pellicciotti, F., Fontrodona-Bach, A., Rounce, D. R., Fyffe, C. L., Anderson,
L. S., Ayala, Á., … Winter-Billington, A. (2026). DCG-MIP: The debris-covered
glacier melt model intercomparison experiment. The Cryosphere. Copernicus
Publications. https://doi.org/10.5194/tc-20-1895-2026'
chicago: 'Pellicciotti, Francesca, Adrià Fontrodona-Bach, David R. Rounce, Catriona
Louise Fyffe, Leif S. Anderson, Álvaro Ayala, Ben W. Brock, et al. “DCG-MIP: The
Debris-Covered Glacier Melt Model Intercomparison Experiment.” The Cryosphere.
Copernicus Publications, 2026. https://doi.org/10.5194/tc-20-1895-2026.'
ieee: 'F. Pellicciotti et al., “DCG-MIP: The debris-covered glacier melt
model intercomparison experiment,” The Cryosphere, vol. 20, no. 3. Copernicus
Publications, pp. 1895–1928, 2026.'
ista: 'Pellicciotti F, Fontrodona-Bach A, Rounce DR, Fyffe CL, Anderson LS, Ayala
Á, Brock BW, Buri P, Fugger S, Fujita K, GANTAYAT P, Groos AR, Immerzeel W, Kneib
M, Mayer C, MacDonell S, McCarthy M, McPhee J, Miles E, Purdie H, Rets E, Sakai
A, Shaw T, Steiner J, Wagnon P, Winter-Billington A. 2026. DCG-MIP: The debris-covered
glacier melt model intercomparison experiment. The Cryosphere. 20(3), 1895–1928.'
mla: 'Pellicciotti, Francesca, et al. “DCG-MIP: The Debris-Covered Glacier Melt
Model Intercomparison Experiment.” The Cryosphere, vol. 20, no. 3, Copernicus
Publications, 2026, pp. 1895–928, doi:10.5194/tc-20-1895-2026.'
short: F. Pellicciotti, A. Fontrodona-Bach, D.R. Rounce, C.L. Fyffe, L.S. Anderson,
Á. Ayala, B.W. Brock, P. Buri, S. Fugger, K. Fujita, P. GANTAYAT, A.R. Groos,
W. Immerzeel, M. Kneib, C. Mayer, S. MacDonell, M. McCarthy, J. McPhee, E. Miles,
H. Purdie, E. Rets, A. Sakai, T. Shaw, J. Steiner, P. Wagnon, A. Winter-Billington,
The Cryosphere 20 (2026) 1895–1928.
corr_author: '1'
date_created: 2026-05-07T08:48:38Z
date_published: 2026-04-02T00:00:00Z
date_updated: 2026-05-18T06:12:56Z
day: '02'
ddc:
- '550'
department:
- _id: FrPe
doi: 10.5194/tc-20-1895-2026
file:
- access_level: open_access
checksum: f15abad4ee360d41a3e8794f068711fc
content_type: application/pdf
creator: dernst
date_created: 2026-05-18T06:07:53Z
date_updated: 2026-05-18T06:07:53Z
file_id: '21886'
file_name: 2026_Cryosphere_Pellicciotti.pdf
file_size: 3168394
relation: main_file
success: 1
file_date_updated: 2026-05-18T06:07:53Z
has_accepted_license: '1'
intvolume: ' 20'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1895-1928
publication: The Cryosphere
publication_identifier:
eissn:
- 1994-0424
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'DCG-MIP: The debris-covered glacier melt model intercomparison experiment'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21838'
abstract:
- lang: eng
text: We explore the use of a photoacid in a chemical reaction cycle, which allows
for the controlled sol‐to‐gel transition of a saccharide aldehyde‐based self‐assembling
system. The modulation of the pH with light enables to generate chemical fuels
in situ, thus triggering monomer activation and gelation. Our efforts represent
a promising step toward dissipative self‐assembled systems with a higher degree
of spatiotemporal control.
acknowledgement: J.S.V. and T.M.H. acknowledge funding from ERC-2017-STG “Life-Cycle”
(757910) and ERC-2022-CoG “Suprabot” (101087514). A.L-A. acknowledges the European
Union's Horizon 2020 Research and Innovation Program under the Marie Skłodowska-Curie
grant agreement no. 812868 for Ph.D. funding. R.K. acknowledges support through
the Award for Research Cooperation and High Excellence in Science (ARCHES) from
the Federal German Ministry and Research.
article_number: e70037
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Alvaro
full_name: Lopez‐Acosta, Alvaro
last_name: Lopez‐Acosta
- first_name: Jorge S.
full_name: Valera, Jorge S.
last_name: Valera
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Thomas M.
full_name: Hermans, Thomas M.
last_name: Hermans
citation:
ama: Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. Photoacid‐mediated controllable
gelation in a chemical reaction cycle. ChemSystemsChem. 2026;8(3). doi:10.1002/syst.70037
apa: Lopez‐Acosta, A., Valera, J. S., Klajn, R., & Hermans, T. M. (2026). Photoacid‐mediated
controllable gelation in a chemical reaction cycle. ChemSystemsChem. Wiley.
https://doi.org/10.1002/syst.70037
chicago: Lopez‐Acosta, Alvaro, Jorge S. Valera, Rafal Klajn, and Thomas M. Hermans.
“Photoacid‐mediated Controllable Gelation in a Chemical Reaction Cycle.” ChemSystemsChem.
Wiley, 2026. https://doi.org/10.1002/syst.70037.
ieee: A. Lopez‐Acosta, J. S. Valera, R. Klajn, and T. M. Hermans, “Photoacid‐mediated
controllable gelation in a chemical reaction cycle,” ChemSystemsChem, vol.
8, no. 3. Wiley, 2026.
ista: Lopez‐Acosta A, Valera JS, Klajn R, Hermans TM. 2026. Photoacid‐mediated controllable
gelation in a chemical reaction cycle. ChemSystemsChem. 8(3), e70037.
mla: Lopez‐Acosta, Alvaro, et al. “Photoacid‐mediated Controllable Gelation in a
Chemical Reaction Cycle.” ChemSystemsChem, vol. 8, no. 3, e70037, Wiley,
2026, doi:10.1002/syst.70037.
short: A. Lopez‐Acosta, J.S. Valera, R. Klajn, T.M. Hermans, ChemSystemsChem 8 (2026).
date_created: 2026-05-07T08:51:01Z
date_published: 2026-04-06T00:00:00Z
date_updated: 2026-05-18T06:59:10Z
day: '06'
ddc:
- '540'
department:
- _id: RaKl
doi: 10.1002/syst.70037
file:
- access_level: open_access
checksum: c51e985ac2f2cefb273fdf2cc6ab87e4
content_type: application/pdf
creator: dernst
date_created: 2026-05-18T06:29:57Z
date_updated: 2026-05-18T06:29:57Z
file_id: '21887'
file_name: 2026_ChemSystemsChem_LopezAcosta.pdf
file_size: 1118636
relation: main_file
success: 1
file_date_updated: 2026-05-18T06:29:57Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: ChemSystemsChem
publication_identifier:
eissn:
- 2570-4206
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Photoacid‐mediated controllable gelation in a chemical reaction cycle
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21839'
abstract:
- lang: eng
text: "Background & Aims: To develop and validate a CT-based radiomics model to
assess HVPG and predict a composite endpoint of liver-related events (LRE: decompensation
and liver-related death) in patients with cirrhosis.\r\n\r\nMethods: This retrospective
study included 357 cirrhosis patients, who received invasive HVPG measurements,
120 liver-healthy controls (training cohort) and 85 and 100 cirrhosis patients
(internal and external validation cohorts, respectively), and contrast-enhanced
abdominal CTs. After volumetric segmentation of the liver and spleen on CT, Bayesian
parameter optimization was used for selection of extracted features and hyperparameter
tuning in random forest or elastic net models. Prediction accuracy was evaluated
using Pearson correlation coefficients of predicted (’radio-HVPG’) and invasive
HVPG. Discrimination between relevant HVPG cut-offs was determined by receiver
operating characteristic (ROC) analysis. The predictive value of radio-HVPG and
invasive-HVPG for LRE was compared using Cox regression models.\r\n\r\nResults:
Radio-HVPG, predicted by an optimized random forest model based on 74 selected
CT features, correlated with invasive-HVPG and detected clinically significant
portal hypertension (CSPH: HVPG ≥ 10 mmHg) on the internal (Pearson r = 0.63,
AUC 0.89 [95% CI: 0.81–0.96]) and external (Pearson r = 0.62, AUC 0.80 [95% CI:
0.64–0.91]) validation cohorts. Radio-HVPG predicted LRE when adjusting for MELD
and albumin (adjusted HR: 1.14 [95% CI: 1.04–1.25], p = 0.005) and performed similarly
to invasive-HVPG.\r\n\r\nConclusions: Radiomic features accurately predict HVPG
in patients with cirrhosis and allow risk stratification for LRE in a radiomics-clinical
signature."
acknowledgement: "The computational results presented were partly obtained using the
CLIP cluster (https://clip.science/). The authors thank Clemens Watzenboeck from
the Medical University of Vienna for the assistance in code upload and repository
maintenance. The authors dedicate this work to the memory of Martin Watzenboeck,
who served as first author and whose vision and scientific rigor were fundamental
to the conception and completion of this study. Open Access funding provided by
Medizinische Universitat Wien/KEMÖ. This work was supported by the Vienna Science
and Technology Fund (WWTF) through projects VRG15-005 and NXT 19-008 granted to
J.M and the Clinical Research Group MOTION, Medical University of Vienna, Vienna,
Austria – a Clinical Research Group Programme project funded by the Ludwig Boltzmann
Gesellschaft (Grant Nr LBG_KFG_22_32) with funds from the Fonds Zukunft Österreich.\r\n\r\nP-E.R.'s
research laboratory is supported by the Fondation pour la Recherche Médicale (FRM
EQU202303016287), “Institut National de la Santé et de la Recherche Médicale” (ATIP
AVENIR), the “Agence Nationale de la Recherche” (ANR-18-CE14-0006-01, RHU QUID-NASH,
ANR-18-IDEX-0001, ANR-22-CE14-0002) by « Émergence, Ville de Paris », by Fondation
ARC, by the European Union's Horizon 2020 research and innovation programme under
grant agreement No 847949 and by France 2030 RHU LIVER-TRACK."
article_number: e70633
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Celine
full_name: Sin, Celine
last_name: Sin
- first_name: Martin Luther
full_name: Watzenboeck, Martin Luther
last_name: Watzenboeck
- first_name: Eugenia B
full_name: Iofinova, Eugenia B
id: f9a17499-f6e0-11ea-865d-fdf9a3f77117
last_name: Iofinova
orcid: 0000-0002-7778-3221
- first_name: Lorenz
full_name: Balcar, Lorenz
last_name: Balcar
- first_name: Georg
full_name: Semmler, Georg
last_name: Semmler
- first_name: Bernhard
full_name: Scheiner, Bernhard
last_name: Scheiner
- first_name: Katharina
full_name: Lampichler, Katharina
last_name: Lampichler
- first_name: Mattias
full_name: Mandorfer, Mattias
last_name: Mandorfer
- first_name: Lucile
full_name: Moga, Lucile
last_name: Moga
- first_name: Pierre‐Emmanuel
full_name: Rautou, Pierre‐Emmanuel
last_name: Rautou
- first_name: Maxime
full_name: Ronot, Maxime
last_name: Ronot
- first_name: Jörg
full_name: Menche, Jörg
last_name: Menche
- first_name: Thomas
full_name: Reiberger, Thomas
last_name: Reiberger
- first_name: Martina
full_name: Scharitzer, Martina
last_name: Scharitzer
citation:
ama: Sin C, Watzenboeck ML, Iofinova EB, et al. Radiomics‐based assessment of portal
hypertension severity and risk stratification of cirrhotic patients using routine
CT scans. Liver International. 2026;46(5). doi:10.1111/liv.70633
apa: Sin, C., Watzenboeck, M. L., Iofinova, E. B., Balcar, L., Semmler, G., Scheiner,
B., … Scharitzer, M. (2026). Radiomics‐based assessment of portal hypertension
severity and risk stratification of cirrhotic patients using routine CT scans.
Liver International. Wiley. https://doi.org/10.1111/liv.70633
chicago: Sin, Celine, Martin Luther Watzenboeck, Eugenia B Iofinova, Lorenz Balcar,
Georg Semmler, Bernhard Scheiner, Katharina Lampichler, et al. “Radiomics‐based
Assessment of Portal Hypertension Severity and Risk Stratification of Cirrhotic
Patients Using Routine CT Scans.” Liver International. Wiley, 2026. https://doi.org/10.1111/liv.70633.
ieee: C. Sin et al., “Radiomics‐based assessment of portal hypertension severity
and risk stratification of cirrhotic patients using routine CT scans,” Liver
International, vol. 46, no. 5. Wiley, 2026.
ista: Sin C, Watzenboeck ML, Iofinova EB, Balcar L, Semmler G, Scheiner B, Lampichler
K, Mandorfer M, Moga L, Rautou P, Ronot M, Menche J, Reiberger T, Scharitzer M.
2026. Radiomics‐based assessment of portal hypertension severity and risk stratification
of cirrhotic patients using routine CT scans. Liver International. 46(5), e70633.
mla: Sin, Celine, et al. “Radiomics‐based Assessment of Portal Hypertension Severity
and Risk Stratification of Cirrhotic Patients Using Routine CT Scans.” Liver
International, vol. 46, no. 5, e70633, Wiley, 2026, doi:10.1111/liv.70633.
short: C. Sin, M.L. Watzenboeck, E.B. Iofinova, L. Balcar, G. Semmler, B. Scheiner,
K. Lampichler, M. Mandorfer, L. Moga, P. Rautou, M. Ronot, J. Menche, T. Reiberger,
M. Scharitzer, Liver International 46 (2026).
date_created: 2026-05-07T08:51:47Z
date_published: 2026-05-01T00:00:00Z
date_updated: 2026-05-18T07:20:20Z
day: '01'
ddc:
- '570'
doi: 10.1111/liv.70633
external_id:
pmid:
- '41943460'
file:
- access_level: open_access
checksum: fafcc0b88b8e8caed85849627305d9ba
content_type: application/pdf
creator: dernst
date_created: 2026-05-18T07:10:31Z
date_updated: 2026-05-18T07:10:31Z
file_id: '21888'
file_name: 2026_LiverInternational_Sin.pdf
file_size: 3550462
relation: main_file
success: 1
file_date_updated: 2026-05-18T07:10:31Z
has_accepted_license: '1'
intvolume: ' 46'
issue: '5'
keyword:
- computed tomography
- liver
- portal hypertension
- radiomics
- spleen
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Liver International
publication_identifier:
eissn:
- 1478-3231
issn:
- 1478-3223
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Radiomics‐based assessment of portal hypertension severity and risk stratification
of cirrhotic patients using routine CT scans
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 46
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21840'
abstract:
- lang: eng
text: The transport properties of nanofluidic channels are usually studied under
constant (DC) voltage or pressure driving. However, the frequency response under
sinusoidal (AC) drivings offers rich insights into the time-dependent transport
mechanisms. Inspired by recent electrochemical approaches, we investigate the
couplings between ionic and electronic transport under AC driving. We show that
conduction electrons of the channel walls participate in ionic current via capacitive
electrochemical coupling, defining a critical frequency and length scale where
electron-dominated conductivity emerges. We further analyze how electron–ion coupling
modifies electro-osmotic flows and demonstrate that fluctuation-induced momentum
transfer between the electrolyte and wall electrons produces distinct AC transport
signatures, depending on the charge carrier polarity. Altogether, we establish
a frequency-dependent transport matrix that couples ionic, electronic, and hydrodynamic
flows. These findings establish AC nanofluidic transport as a powerful probe of
interfacial phenomena under confinement and suggest new directions for engineering
nanofluidic functionalities through electron–electrolyte coupling.
acknowledgement: The authors thank Nicolas Chapuis for fruitful discussions. L.B.
acknowledges support from the ERC project n-AQUA under Grant Agreement No. 101071937.
B.C. acknowledges support from the CFM Foundation and the NOMIS Foundation. N.K.
acknowledges support from the Swiss National Science Foundation (SNSF) under Grant
No. CRSK-2_237930.
article_number: '134704'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Baptiste
full_name: Coquinot, Baptiste
id: f8417bd4-f599-11ee-a482-b927e3ed1e8e
last_name: Coquinot
orcid: 0000-0001-5524-596X
- first_name: Mathieu
full_name: Lizée, Mathieu
last_name: Lizée
- first_name: Lydéric
full_name: Bocquet, Lydéric
last_name: Bocquet
- first_name: Nikita
full_name: Kavokine, Nikita
last_name: Kavokine
citation:
ama: Coquinot B, Lizée M, Bocquet L, Kavokine N. Electron–electrolyte coupling in
AC transport through nanofluidic channels. The Journal of Chemical Physics.
2026;164(13). doi:10.1063/5.0313352
apa: Coquinot, B., Lizée, M., Bocquet, L., & Kavokine, N. (2026). Electron–electrolyte
coupling in AC transport through nanofluidic channels. The Journal of Chemical
Physics. AIP Publishing. https://doi.org/10.1063/5.0313352
chicago: Coquinot, Baptiste, Mathieu Lizée, Lydéric Bocquet, and Nikita Kavokine.
“Electron–Electrolyte Coupling in AC Transport through Nanofluidic Channels.”
The Journal of Chemical Physics. AIP Publishing, 2026. https://doi.org/10.1063/5.0313352.
ieee: B. Coquinot, M. Lizée, L. Bocquet, and N. Kavokine, “Electron–electrolyte
coupling in AC transport through nanofluidic channels,” The Journal of Chemical
Physics, vol. 164, no. 13. AIP Publishing, 2026.
ista: Coquinot B, Lizée M, Bocquet L, Kavokine N. 2026. Electron–electrolyte coupling
in AC transport through nanofluidic channels. The Journal of Chemical Physics.
164(13), 134704.
mla: Coquinot, Baptiste, et al. “Electron–Electrolyte Coupling in AC Transport through
Nanofluidic Channels.” The Journal of Chemical Physics, vol. 164, no. 13,
134704, AIP Publishing, 2026, doi:10.1063/5.0313352.
short: B. Coquinot, M. Lizée, L. Bocquet, N. Kavokine, The Journal of Chemical Physics
164 (2026).
date_created: 2026-05-07T08:53:03Z
date_published: 2026-04-07T00:00:00Z
date_updated: 2026-05-18T07:34:57Z
day: '07'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1063/5.0313352
external_id:
arxiv:
- '2505.02478'
file:
- access_level: open_access
checksum: a896969c829be2a79859bd277f87b44c
content_type: application/pdf
creator: dernst
date_created: 2026-05-18T07:31:23Z
date_updated: 2026-05-18T07:31:23Z
file_id: '21889'
file_name: 2026_JourChemPhysics_Coquinot.pdf
file_size: 5497515
relation: main_file
success: 1
file_date_updated: 2026-05-18T07:31:23Z
has_accepted_license: '1'
intvolume: ' 164'
issue: '13'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: The Journal of Chemical Physics
publication_identifier:
eissn:
- 1089-7690
issn:
- 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electron–electrolyte coupling in AC transport through nanofluidic channels
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 164
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21841'
abstract:
- lang: eng
text: The long-standing notion that genotypes map to phenotypes through simple one
gene–one trait relationships continues to shape both research in the life sciences
and public understanding, with implications for policy and funding priorities.
Yet this paradigm is increasingly recognized as inadequate for explaining continuous
phenotypic variation and the complex genetic architectures of the genotype–phenotype
map. Modern genetics emerged from the early 20th-century synthesis of Mendelian
and biometric schools of heredity, with R.A. Fisher demonstrating early on how
multiple discrete loci could collectively produce continuous variation. Despite
this fundamental insight, Mendelism—with its focus on single genes and standardized
genetic backgrounds—became the dominant framework, shaping current genetics research
and molecular biology as well as science education. The advent of large-scale
genomic data has revealed yet again the limitations of this reductionist approach.
Evidence from quantitative genetics now shows that most phenotypes arise from
complex networks of many interdependent genes and their dynamic responses to environmental
perturbations. Here we trace the historical roots of how Mendelian classical genetics
departed from the biometric school to create the current predominant paradigm
in genetics, despite fundamentally unresolved issues. Moving on from this one-sided
paradigm will require systematic development of integrative, evolutionarily grounded
experimental approaches that better capture the multigenic and context-dependent
nature of inheritance. Achieving such an extended perspective will require methodological
innovation, including advances in large-scale (e.g. automated) phenotyping. Dedicated
research programs will be necessary to advance a new era of genetic research into
the complex mechanisms underlying phenotypic variation.
acknowledgement: We thank a variety of further colleagues for the many inspiring discussions
on the nature of heredity, especially the workshops in Berlin. Special thanks also
to the Stellenbosch Institute for Advanced Studies (STIAS) to provide DT the leisure
and freedom to write up the first version of this perspective. Thanks also to three
reviewers who have helped to improve the manuscript. Two dedicated symposia on the
topic were funded by the Max-Planck Society.
article_number: iyag024
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Diethard
full_name: Tautz, Diethard
last_name: Tautz
- first_name: Luisa F
full_name: Pallares, Luisa F
last_name: Pallares
- first_name: Leif
full_name: Andersson, Leif
last_name: Andersson
- first_name: Neda
full_name: Barghi, Neda
last_name: Barghi
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Rachael
full_name: Bay, Rachael
last_name: Bay
- first_name: Yingguang Frank
full_name: Chan, Yingguang Frank
last_name: Chan
- first_name: Angela
full_name: Hancock, Angela
last_name: Hancock
- first_name: Tobias S
full_name: Kaiser, Tobias S
last_name: Kaiser
- first_name: Daniel
full_name: Koenig, Daniel
last_name: Koenig
- first_name: Zacharias
full_name: Kontarakis, Zacharias
last_name: Kontarakis
- first_name: Miriam
full_name: Liedvogel, Miriam
last_name: Liedvogel
- first_name: Juliette
full_name: de Meaux, Juliette
last_name: de Meaux
- first_name: Magnus
full_name: Nordborg, Magnus
last_name: Nordborg
- first_name: Abraham A
full_name: Palmer, Abraham A
last_name: Palmer
- first_name: Michael
full_name: Purugganan, Michael
last_name: Purugganan
- first_name: Christian
full_name: Schlötterer, Christian
last_name: Schlötterer
- first_name: Karl
full_name: Schmid, Karl
last_name: Schmid
- first_name: Didier Y R
full_name: Stainier, Didier Y R
last_name: Stainier
- first_name: Detlef
full_name: Weigel, Detlef
last_name: Weigel
- first_name: Jochen B W
full_name: Wolf, Jochen B W
last_name: Wolf
- first_name: Dieter
full_name: Ebert, Dieter
last_name: Ebert
- first_name: Greg
full_name: Gibson, Greg
last_name: Gibson
citation:
ama: 'Tautz D, Pallares LF, Andersson L, et al. Beyond Mendel: A call to revisit
the genotype–phenotype map through new experimental paradigms. Genetics.
2026;232(4). doi:10.1093/genetics/iyag024'
apa: 'Tautz, D., Pallares, L. F., Andersson, L., Barghi, N., Barton, N. H., Bay,
R., … Gibson, G. (2026). Beyond Mendel: A call to revisit the genotype–phenotype
map through new experimental paradigms. Genetics. Oxford University Press.
https://doi.org/10.1093/genetics/iyag024'
chicago: 'Tautz, Diethard, Luisa F Pallares, Leif Andersson, Neda Barghi, Nicholas
H Barton, Rachael Bay, Yingguang Frank Chan, et al. “Beyond Mendel: A Call to
Revisit the Genotype–Phenotype Map through New Experimental Paradigms.” Genetics.
Oxford University Press, 2026. https://doi.org/10.1093/genetics/iyag024.'
ieee: 'D. Tautz et al., “Beyond Mendel: A call to revisit the genotype–phenotype
map through new experimental paradigms,” Genetics, vol. 232, no. 4. Oxford
University Press, 2026.'
ista: 'Tautz D, Pallares LF, Andersson L, Barghi N, Barton NH, Bay R, Chan YF, Hancock
A, Kaiser TS, Koenig D, Kontarakis Z, Liedvogel M, de Meaux J, Nordborg M, Palmer
AA, Purugganan M, Schlötterer C, Schmid K, Stainier DYR, Weigel D, Wolf JBW, Ebert
D, Gibson G. 2026. Beyond Mendel: A call to revisit the genotype–phenotype map
through new experimental paradigms. Genetics. 232(4), iyag024.'
mla: 'Tautz, Diethard, et al. “Beyond Mendel: A Call to Revisit the Genotype–Phenotype
Map through New Experimental Paradigms.” Genetics, vol. 232, no. 4, iyag024,
Oxford University Press, 2026, doi:10.1093/genetics/iyag024.'
short: D. Tautz, L.F. Pallares, L. Andersson, N. Barghi, N.H. Barton, R. Bay, Y.F.
Chan, A. Hancock, T.S. Kaiser, D. Koenig, Z. Kontarakis, M. Liedvogel, J. de Meaux,
M. Nordborg, A.A. Palmer, M. Purugganan, C. Schlötterer, K. Schmid, D.Y.R. Stainier,
D. Weigel, J.B.W. Wolf, D. Ebert, G. Gibson, Genetics 232 (2026).
date_created: 2026-05-07T08:53:40Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-05-18T07:51:26Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/genetics/iyag024
external_id:
pmid:
- '41701356'
file:
- access_level: open_access
checksum: 5a862c539f9dec4511277ad8927c549c
content_type: application/pdf
creator: dernst
date_created: 2026-05-18T07:48:45Z
date_updated: 2026-05-18T07:48:45Z
file_id: '21890'
file_name: 2026_Genetics_Tautz.pdf
file_size: 542844
relation: main_file
success: 1
file_date_updated: 2026-05-18T07:48:45Z
has_accepted_license: '1'
intvolume: ' 232'
issue: '4'
keyword:
- classic genetics
- quantitative genetics
- genotype–phenotype map
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
eissn:
- 1943-2631
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Beyond Mendel: A call to revisit the genotype–phenotype map through new experimental
paradigms'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 232
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21842'
abstract:
- lang: eng
text: "AM CVn stars are ultra-compact semi-detached binaries consisting of a white
dwarf primary and a hydrogen-depleted secondary. In this\r\npaper, we present
spectroscopic and photometric results of 15 transient sources pre-classified as
AM CVn candidates. Our analysis confirms\r\n9 systems of the type AM CVn, 3 hydrogen-rich
cataclysmic variables (accreting white dwarfs with near-main-sequence stars for
donors),\r\nand 3 systems that could be evolved cataclysmic variables. Eight of
the AM CVn stars are analysed spectroscopically for the first time,\r\nwhich increases
the number of spectroscopically confirmed AM CVns by about 10%. TESS data revealed
the orbital period of the AM CVn\r\nstar ASASSN-20pv to be Porb =27.282 min, which
helps to constrain the possible values of its mass ratio. TESS also helped to
determine\r\nthe superhump periods of one AM CVn star (ASASSN-19ct, Psh =30.94
min) and two cataclysmic variables we classify as WZ Sge stars\r\n(Psh =90.77
min for ZTF18aaaasnn and Psh =91.6min for ASASSN-15na).We identified very different
abundances in the spectra of theAM\r\nCVns binaries ASASSN-15kf and ASASSN-20pv
(both Porb ∼27.5min), suggesting different type of donors. Six of the studied
AMCVns are\r\nX-ray sources, which helped to determine their mass accretion rates.
Photometry shows that the duration of all the superoutbursts detected\r\nin the
AM CVns is consistent with expectations from the disc instability model. Finally,
we provide refined criteria for the identification of\r\nnew systems using all-sky
surveys such as LSST."
acknowledgement: "We are grateful to the anonymous referee for providing\r\nus with
useful comments and suggestions that improved our manuscript.\r\nJK and LRS acknowledge
support from NASA grants NNH22ZDA001N-6152\r\nand 80NSSC24K0638. MPM is partially
supported by the Swiss National\r\nScience Foundation IZSTZ0_216537 and by UNAM
PAPIIT-IG101224. Based\r\non observations obtained at the international Gemini Observatory,
a program\r\nof NSF NOIRLab, which is managed by the Association of Universities
for\r\nResearch in Astronomy (AURA) under a cooperative agreement with the U.S.\r\nNational
Science Foundation on behalf of the Gemini Observatory partnership:\r\nthe U.S.
National Science Foundation (United States), National Research\r\nCouncil (Canada),
Agencia Nacional de Investigación y Desarrollo (Chile), Ministerio de Ciencia, Tecnología
e Innovación (Argentina), Ministério\r\nda Ciência, Tecnologia, Inovações e Comunicações
(Brazil), and Korea\r\nAstronomy and Space Science Institute (Republic of Korea).
The Gemini\r\ndata were obtained from programs GN-2023B-Q-310 and GS-2024A-Q-311\r\n(PI:
Rivera Sandoval) and processed using DRAGONS (Data Reduction for\r\nAstronomy from
Gemini Observatory North and South) The Digitized Sky\r\nSurveys were produced at
the Space Telescope Science Institute under U.S.\r\nGovernment grant NAG W-2166.
The images of these surveys are based on\r\nphotographic data obtained using the
Oschin Schmidt Telescope on Palomar\r\nMountain and the UK Schmidt Telescope. The
plates were processed into the\r\npresent compressed digital form with the permission
of these institutions.\r\nThe National Geographic Society – Palomar Observatory
Sky Atlas (POSS-I)\r\nwas made by the California Institute of Technology with grants
from the\r\nNational Geographic Society. The Second Palomar Observatory Sky Survey\r\n(POSS-II)
was made by the California Institute of Technology with funds\r\nfrom the National
Science Foundation, the National Geographic Society, the\r\nSloan Foundation, the
Samuel Oschin Foundation, and the Eastman Kodak\r\nCorporation. The Oschin Schmidt
Telescope is operated by the California\r\nInstitute of Technology and Palomar Observatory.
The UK Schmidt Telescope\r\nwas operated by the Royal Observatory Edinburgh, with
funding from the\r\nUK Science and Engineering Research Council (later the UK Particle
Physics\r\nand Astronomy Research Council), until 1988 June, and thereafter by the\r\nAnglo-Australian
Observatory. The blue plates of the southern Sky Atlas\r\nand its Equatorial Extension
(together known as the SERC-J), as well as the\r\nEquatorial Red (ER), and the Second
Epoch [red] Survey (SES) were all taken\r\nwith the UK Schmidt. Supplemental funding
for sky-survey work at the ST\r\nScI is provided by the European Southern Observatory.
Based on observations\r\nobtained with the Samuel Oschin Telescope 48-inch and the
60-inch Telescope\r\nat the Palomar Observatory as part of the Zwicky Transient
Facility project.\r\nZTF is supported by the National Science Foundation under Grants
No. AST-\r\n1440341 and AST-2034437 and a collaboration including current partners\r\nCaltech,
IPAC, the Oskar Klein Center at Stockholm University, the University\r\nof Maryland,
University of California, Berkeley, the University of Wisconsin\r\nat Milwaukee,
University of Warwick, Ruhr University, Cornell University,\r\nNorthwestern University,
and Drexel University. Operations are conducted\r\nby COO, IPAC, and UW. This work
has used data from the European\r\nSpace Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia),\r\nprocessed
by the Gaia Data Processing and Analysis Consortium (DPAC,\r\nhttps://www.cosmos.esa.int/web/gaia/dpac/consortium).
Funding for the\r\nDPAC has been provided by national institutions, in particular,
the institutions\r\nparticipating in the Gaia Multilateral Agreement. We acknowledge
with\r\nthanks the variable star observations from the AAVSO International Database\r\ncontributed
by observers worldwide and used in this research. This paper\r\nincludes data collected
by the TESS mission. Funding for the TESS mission\r\nis provided by the NASA Science
Mission Directorate. Some of the data\r\npresented in this paper were obtained from
the B. Mikulski Archive for Space\r\nTelescopes (MAST). This research has made use
of the SIMBAD database,\r\noperated at CDS, Strasbourg, France. This research has
made use of ‘Aladin\r\nsky atlas’ developed at CDS, Strasbourg Observatory, France.
This research\r\nhas made use of the VizieR catalogue access tool, CDS, Strasbourg,
France."
article_number: e052
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jan
full_name: Kára, Jan
last_name: Kára
- first_name: Liliana
full_name: Rivera Sandoval, Liliana
last_name: Rivera Sandoval
- first_name: Wendy
full_name: Mendoza, Wendy
last_name: Mendoza
- first_name: Thomas
full_name: Maccarone, Thomas
last_name: Maccarone
- first_name: Manuel
full_name: Pichardo Marcano, Manuel
last_name: Pichardo Marcano
- first_name: Luis E.
full_name: Salazar Manzano, Luis E.
last_name: Salazar Manzano
- first_name: Ryan J.
full_name: Oelkers, Ryan J.
last_name: Oelkers
- first_name: Joannes C
full_name: van Roestel, Joannes C
id: 4d122fc8-6083-11f0-87a5-97d68b860333
last_name: van Roestel
citation:
ama: Kára J, Rivera Sandoval L, Mendoza W, et al. A study of transients from ground-based
surveys reveals new ultra-compact accreting white dwarf binaries. Publications
of the Astronomical Society of Australia. 2026;43. doi:10.1017/pasa.2026.10184
apa: Kára, J., Rivera Sandoval, L., Mendoza, W., Maccarone, T., Pichardo Marcano,
M., Salazar Manzano, L. E., … van Roestel, J. C. (2026). A study of transients
from ground-based surveys reveals new ultra-compact accreting white dwarf binaries.
Publications of the Astronomical Society of Australia. Cambridge University
Press. https://doi.org/10.1017/pasa.2026.10184
chicago: Kára, Jan, Liliana Rivera Sandoval, Wendy Mendoza, Thomas Maccarone, Manuel
Pichardo Marcano, Luis E. Salazar Manzano, Ryan J. Oelkers, and Joannes C van
Roestel. “A Study of Transients from Ground-Based Surveys Reveals New Ultra-Compact
Accreting White Dwarf Binaries.” Publications of the Astronomical Society of
Australia. Cambridge University Press, 2026. https://doi.org/10.1017/pasa.2026.10184.
ieee: J. Kára et al., “A study of transients from ground-based surveys reveals
new ultra-compact accreting white dwarf binaries,” Publications of the Astronomical
Society of Australia, vol. 43. Cambridge University Press, 2026.
ista: Kára J, Rivera Sandoval L, Mendoza W, Maccarone T, Pichardo Marcano M, Salazar
Manzano LE, Oelkers RJ, van Roestel JC. 2026. A study of transients from ground-based
surveys reveals new ultra-compact accreting white dwarf binaries. Publications
of the Astronomical Society of Australia. 43, e052.
mla: Kára, Jan, et al. “A Study of Transients from Ground-Based Surveys Reveals
New Ultra-Compact Accreting White Dwarf Binaries.” Publications of the Astronomical
Society of Australia, vol. 43, e052, Cambridge University Press, 2026, doi:10.1017/pasa.2026.10184.
short: J. Kára, L. Rivera Sandoval, W. Mendoza, T. Maccarone, M. Pichardo Marcano,
L.E. Salazar Manzano, R.J. Oelkers, J.C. van Roestel, Publications of the Astronomical
Society of Australia 43 (2026).
date_created: 2026-05-07T08:55:00Z
date_published: 2026-03-27T00:00:00Z
date_updated: 2026-05-12T06:57:40Z
day: '27'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1017/pasa.2026.10184
file:
- access_level: open_access
checksum: f8f3cd3765948e8b276176c71c9d4e02
content_type: application/pdf
creator: dernst
date_created: 2026-05-12T06:54:10Z
date_updated: 2026-05-12T06:54:10Z
file_id: '21862'
file_name: 2026_PublAstronomicalSocAustralia_Kara.pdf
file_size: 3681016
relation: main_file
success: 1
file_date_updated: 2026-05-12T06:54:10Z
has_accepted_license: '1'
intvolume: ' 43'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Publications of the Astronomical Society of Australia
publication_identifier:
eissn:
- 1448-6083
issn:
- 1323-3580
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A study of transients from ground-based surveys reveals new ultra-compact accreting
white dwarf binaries
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21844'
abstract:
- lang: eng
text: Little red dots (LRDs) are a newly identified class of broad-line active galactic
nuclei (AGNs) with a distinctive V-shaped spectrum characterized by red optical
and blue UV continuum emission. Their high abundance at redshifts of z ∼ 6–8 and
decline at lower redshifts suggest a transient origin. We propose that the spectral
shape of LRDs originates from compact binary black hole systems, in which each
black hole is surrounded by a mini-disk and embedded within a larger circumbinary
disk. With a binary separation of ≲103 Schwarzschild radii, the Wien tail of a
T ≃ 5000 K blackbody spectrum at the inner edge of the circumbinary disk produces
the red optical emission, while the mini-disks power the UV continuum. Binary
torques carve out a gap between the circumbinary disk and the mini-disks, setting
the turnover wavelength of the V-shaped spectrum around the Balmer limit. This
scenario naturally reproduces LRD spectra requiring only modest dust attenuation
(AV ≲ 1 mag), resolving overestimated luminosities for LRDs in previous studies
and alleviating a tension with the so-called Sołtan argument. This model predicts
distinct spectral evolution as the binary orbit decays through binary disk interactions
and gravitational-wave (GW) emission, linking early-stage “proto-LRD” binaries
to the broader AGN population and late-stage “LRD descendants” to coalescing binaries
detectable in GW experiments.
acknowledgement: We greatly thank Kenta Hotokezaka and Hanpu Liu for constructive
discussions. K.I., J.S., X.C., and L.C.H. acknowledge support from National Natural
Science Foundation of China (grant Nos. 12573015, 1251101148, 12233001, and 12473037),
the Beijing Natural Science Foundation (grant No. IS25003), and the China Manned
Space Program (grant No. CMS-CSST-2025-A09). J.S. is also supported by “The Fundamental
Research Funds for the Central Universities, Peking University” (grant No. 7100604896).
Z.H. acknowledges support by US NSF grant AST-2006176 and by NASA grant Nos. 80NSSC24K0440
and 80NSSC22K0822.
article_number: '25'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Kohei
full_name: Inayoshi, Kohei
last_name: Inayoshi
- first_name: Jinyi
full_name: Shangguan, Jinyi
last_name: Shangguan
- first_name: Xian
full_name: Chen, Xian
last_name: Chen
- first_name: Luis C.
full_name: Ho, Luis C.
last_name: Ho
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
citation:
ama: Inayoshi K, Shangguan J, Chen X, Ho LC, Haiman Z. The emergence of Little Red
Dots from binary massive black holes. The Astrophysical Journal. 2026;1002(1).
doi:10.3847/1538-4357/ae548d
apa: Inayoshi, K., Shangguan, J., Chen, X., Ho, L. C., & Haiman, Z. (2026).
The emergence of Little Red Dots from binary massive black holes. The Astrophysical
Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ae548d
chicago: Inayoshi, Kohei, Jinyi Shangguan, Xian Chen, Luis C. Ho, and Zoltán Haiman.
“The Emergence of Little Red Dots from Binary Massive Black Holes.” The Astrophysical
Journal. IOP Publishing, 2026. https://doi.org/10.3847/1538-4357/ae548d.
ieee: K. Inayoshi, J. Shangguan, X. Chen, L. C. Ho, and Z. Haiman, “The emergence
of Little Red Dots from binary massive black holes,” The Astrophysical Journal,
vol. 1002, no. 1. IOP Publishing, 2026.
ista: Inayoshi K, Shangguan J, Chen X, Ho LC, Haiman Z. 2026. The emergence of Little
Red Dots from binary massive black holes. The Astrophysical Journal. 1002(1),
25.
mla: Inayoshi, Kohei, et al. “The Emergence of Little Red Dots from Binary Massive
Black Holes.” The Astrophysical Journal, vol. 1002, no. 1, 25, IOP Publishing,
2026, doi:10.3847/1538-4357/ae548d.
short: K. Inayoshi, J. Shangguan, X. Chen, L.C. Ho, Z. Haiman, The Astrophysical
Journal 1002 (2026).
date_created: 2026-05-10T22:02:14Z
date_published: 2026-05-01T00:00:00Z
date_updated: 2026-05-11T07:09:12Z
day: '01'
ddc:
- '520'
department:
- _id: ZoHa
doi: 10.3847/1538-4357/ae548d
external_id:
arxiv:
- '2505.05322'
file:
- access_level: open_access
checksum: b4506dfef3dd6da335775071d8f2a0a6
content_type: application/pdf
creator: dernst
date_created: 2026-05-11T07:07:22Z
date_updated: 2026-05-11T07:07:22Z
file_id: '21853'
file_name: 2026_AstrophysicalJour_Inayoshi.pdf
file_size: 3041897
relation: main_file
success: 1
file_date_updated: 2026-05-11T07:07:22Z
has_accepted_license: '1'
intvolume: ' 1002'
issue: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: The emergence of Little Red Dots from binary massive black holes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1002
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21845'
abstract:
- lang: eng
text: UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby
the zero-resistance state reappears above 40 tesla after being suppressed with
a field of around 10 tesla. One potential pairing mechanism, invoked in the related
re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of
a ferromagnetic order parameter. However, the requisite ferromagnetic order—present
in both UCoGe and URhGe—is absent in UTe2, and neutron scattering shows instead
that the magnetic susceptibility is peaked at an antiferromagnetic wavevector.
Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle
planes. This quantity is sensitive to the magnetic susceptibility in a direction
transverse to the applied magnetic field—a quantity that is not accessed in conventional
magnetization measurements. We observe a very large decrease in the magnetotropic
susceptibility over a broad range of field orientations, indicating a large increase
in the transverse magnetic susceptibility. Because our technique probes the magnetic
susceptibility in the long wavelength (q = 0) limit, this suggests that the strong
transverse susceptibility arises from ferromagnetic spin fluctuations. These ferromagnetic
fluctuations are likely important for understanding the pairing mechanism in UTe2,
as all three superconducting phases of UTe2 surround this region of enhanced susceptibility
in the field-angle phase diagram.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: We appreciate technical support from Salvatore Bagiante, Evgeniia
Volobueva, Lubuna Shafeek, Ali Bangura, and Zoltán Köllö, and scientific discussions
with Daniel Agterberg, Johnpierre Paglione, Qimiao Si, Josephine Yu and Yue Yu.
V.Z., A.N., M.N., and K.A.M. acknowledge funding received from the European Research
Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
(TROPIC-101078696). V.Z., A.N., M.N., and K.A.M. thank the ISTA Nanofabrication
Facility for technical support. B.J.R. acknowledges funding from the Office of Basic
Energy Sciences of the United States Department of Energy under award number DE-SC0020143
for data analysis and writing. The National High Magnetic Field Laboratory is supported
by the National Science Foundation through NSF/DMR-2128556*, the State of Florida,
and the U.S. Department of Energy. A.S. acknowledges support from the DOE/BES “Science
of 100 T” grant. A.S. thanks Downtown Subscription in Santa Fe, NM, for their patience
in hosting him. Sample preparation and characterization were supported by the NSF
through DMR-2105191.
article_number: '3742'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Valeska
full_name: Zambra, Valeska
id: 467ed36b-dc96-11ea-b7c8-b043a380b282
last_name: Zambra
orcid: 0000-0002-8806-5719
- first_name: Amit
full_name: Nathwani, Amit
id: 1a362536-4d02-11f1-8543-8351136efc50
last_name: Nathwani
- first_name: Muhammad
full_name: Nauman, Muhammad
id: 32c21954-2022-11eb-9d5f-af9f93c24e71
last_name: Nauman
orcid: 0000-0002-2111-4846
- first_name: Sylvia K.
full_name: Lewin, Sylvia K.
last_name: Lewin
- first_name: Corey E.
full_name: Frank, Corey E.
last_name: Frank
- first_name: Nicholas P.
full_name: Butch, Nicholas P.
last_name: Butch
- first_name: Arkady
full_name: Shekhter, Arkady
last_name: Shekhter
- first_name: B. J.
full_name: Ramshaw, B. J.
last_name: Ramshaw
- first_name: Kimberly A
full_name: Modic, Kimberly A
id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
last_name: Modic
orcid: 0000-0001-9760-3147
citation:
ama: Zambra V, Nathwani A, Nauman M, et al. Giant transverse magnetic fluctuations
at the edge of re-entrant superconductivity in UTe2. Nature Communications.
2026;17. doi:10.1038/s41467-026-71899-7
apa: Zambra, V., Nathwani, A., Nauman, M., Lewin, S. K., Frank, C. E., Butch, N.
P., … Modic, K. A. (2026). Giant transverse magnetic fluctuations at the edge
of re-entrant superconductivity in UTe2. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-026-71899-7
chicago: Zambra, Valeska, Amit Nathwani, Muhammad Nauman, Sylvia K. Lewin, Corey
E. Frank, Nicholas P. Butch, Arkady Shekhter, B. J. Ramshaw, and Kimberly A Modic.
“Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity
in UTe2.” Nature Communications. Springer Nature, 2026. https://doi.org/10.1038/s41467-026-71899-7.
ieee: V. Zambra et al., “Giant transverse magnetic fluctuations at the edge
of re-entrant superconductivity in UTe2,” Nature Communications, vol. 17.
Springer Nature, 2026.
ista: Zambra V, Nathwani A, Nauman M, Lewin SK, Frank CE, Butch NP, Shekhter A,
Ramshaw BJ, Modic KA. 2026. Giant transverse magnetic fluctuations at the edge
of re-entrant superconductivity in UTe2. Nature Communications. 17, 3742.
mla: Zambra, Valeska, et al. “Giant Transverse Magnetic Fluctuations at the Edge
of Re-Entrant Superconductivity in UTe2.” Nature Communications, vol. 17,
3742, Springer Nature, 2026, doi:10.1038/s41467-026-71899-7.
short: V. Zambra, A. Nathwani, M. Nauman, S.K. Lewin, C.E. Frank, N.P. Butch, A.
Shekhter, B.J. Ramshaw, K.A. Modic, Nature Communications 17 (2026).
corr_author: '1'
date_created: 2026-05-10T22:02:15Z
date_published: 2026-04-29T00:00:00Z
date_updated: 2026-05-11T06:36:00Z
day: '29'
ddc:
- '530'
department:
- _id: KiMo
- _id: GradSch
doi: 10.1038/s41467-026-71899-7
external_id:
arxiv:
- '2506.08984'
file:
- access_level: open_access
checksum: 8cb95b033ad2a1a7a8181f6f078c05b5
content_type: application/pdf
creator: dernst
date_created: 2026-05-11T06:32:12Z
date_updated: 2026-05-11T06:32:12Z
file_id: '21850'
file_name: 2026_NatureComm_Zambra.pdf
file_size: 1784917
relation: main_file
success: 1
file_date_updated: 2026-05-11T06:32:12Z
has_accepted_license: '1'
intvolume: ' 17'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: bd968c70-d553-11ed-ba76-cde40b0aba64
grant_number: '101078696'
name: Gaining leverage with spin liquids and superconductors
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '21174'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity
in UTe2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21846'
abstract:
- lang: eng
text: 'We compile a sample of 83 little red dots (LRDs) with JWST imaging and find
that a substantial fraction (∼43%, rising to ≳80% for the most luminous LRDs)
host one or more spatially offset, UV-bright companions at projected separations
of 0.5 kpc ≲ d ≲ 5 kpc, with median 〈d〉 = 1.0 kpc. This fraction is even higher
when smaller spatial scales are probed at high signal-to-noise ratio: the two
most strongly lensed LRDs, A383-LRD1 and the newly discovered A68-LRD1, both have
UV-bright companions at separations of only d ∼ 0.3 kpc, below the resolution
limit of most unlensed JWST samples. We explore whether these ubiquitous red/blue
configurations may be physically linked to the formation of LRDs, in analogy with
the “synchronized pair” scenario originally proposed for direct-collapse black
hole formation. In this picture, UV radiation from the companions, with typically
modest stellar masses (M∗ ∼ 108−109 M⊙), suppresses molecular hydrogen cooling
in nearby gas, allowing nearly isothermal collapse and the formation of extremely
compact objects, such as massive black holes, supermassive stars, or quasi-stars.
Using component-resolved photometry and spectral energy distribution modeling,
we infer Lyman–Werner radiation fields of J21,LW ∼ 102.5–105 at the locations
of the red components, comparable to those required in direct-collapse models,
suggesting that the necessary photodissociation conditions are realized in many
LRD systems. This framework provides a simple and self-consistent explanation
for the extreme compactness and distinctive spectral properties of LRDs and links
long-standing theoretical models for early compact object formation directly to
a population now observed with JWST in the early Universe.'
acknowledgement: 'We thank Earl Bellinger, Fabio Pacucci, Andrea Ferrara, and Dale
Kocevski for useful discussions. This work is based on observations made with the
NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski
Archive for Space Telescopes at the Space Telescope Science Institute, which is
operated by the Association of Universities for Research in Astronomy, Inc., under
NASA contract NAS 5-03127 for JWST. These imaging observations are associated with
programs 1345, 1180, 1181, 1243, 6882, 2561, 1324, 4111, and 1895. The compiled
dataset can be accessed at doi:10.17909/1m8f-9c47. The Cosmic Dawn Center (DAWN)
is funded by the Danish National Research Foundation under grant DNRF140. J.M. and
A.T. acknowledge funding by the European Union (ERC, AGENTS, 101076224). This work
was performed in part at Aspen Center for Physics, which is supported by National
Science Foundation grant PHY-2210452. This work used the following Python packages:
Matplotlib (J. D. Hunter 2007), SciPy (P. Virtanen et al. 2020), NumPy (S. van der
Walt et al. 2011), AstroPy (Astropy Collaboration et al. 2022), colossus (B. Diemer
2018), and photutils (L. Bradley et al. 2025).'
article_number: L4
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Josephine F.W.
full_name: Baggen, Josephine F.W.
last_name: Baggen
- first_name: Matthew T.
full_name: Scoggins, Matthew T.
last_name: Scoggins
- first_name: Pieter
full_name: Van Dokkum, Pieter
last_name: Van Dokkum
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
- first_name: Alberto
full_name: Torralba Torregrosa, Alberto
id: 018f0249-0e87-11f0-b167-cbce08fbd541
last_name: Torralba Torregrosa
orcid: 0000-0001-5586-6950
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
citation:
ama: 'Baggen JFW, Scoggins MT, Van Dokkum P, Haiman Z, Torralba Torregrosa A, Matthee
JJ. Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner
sources enabling direct-collapse Black Hole formation. The Astrophysical Journal
Letters. 2026;1002(1). doi:10.3847/2041-8213/ae58a5'
apa: 'Baggen, J. F. W., Scoggins, M. T., Van Dokkum, P., Haiman, Z., Torralba Torregrosa,
A., & Matthee, J. J. (2026). Connecting the dots: UV-bright companions of
Little Red Dots as Lyman–Werner sources enabling direct-collapse Black Hole formation.
The Astrophysical Journal Letters. IOP Publishing. https://doi.org/10.3847/2041-8213/ae58a5'
chicago: 'Baggen, Josephine F.W., Matthew T. Scoggins, Pieter Van Dokkum, Zoltán
Haiman, Alberto Torralba Torregrosa, and Jorryt J Matthee. “Connecting the Dots:
UV-Bright Companions of Little Red Dots as Lyman–Werner Sources Enabling Direct-Collapse
Black Hole Formation.” The Astrophysical Journal Letters. IOP Publishing,
2026. https://doi.org/10.3847/2041-8213/ae58a5.'
ieee: 'J. F. W. Baggen, M. T. Scoggins, P. Van Dokkum, Z. Haiman, A. Torralba Torregrosa,
and J. J. Matthee, “Connecting the dots: UV-bright companions of Little Red Dots
as Lyman–Werner sources enabling direct-collapse Black Hole formation,” The
Astrophysical Journal Letters, vol. 1002, no. 1. IOP Publishing, 2026.'
ista: 'Baggen JFW, Scoggins MT, Van Dokkum P, Haiman Z, Torralba Torregrosa A, Matthee
JJ. 2026. Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner
sources enabling direct-collapse Black Hole formation. The Astrophysical Journal
Letters. 1002(1), L4.'
mla: 'Baggen, Josephine F. W., et al. “Connecting the Dots: UV-Bright Companions
of Little Red Dots as Lyman–Werner Sources Enabling Direct-Collapse Black Hole
Formation.” The Astrophysical Journal Letters, vol. 1002, no. 1, L4, IOP
Publishing, 2026, doi:10.3847/2041-8213/ae58a5.'
short: J.F.W. Baggen, M.T. Scoggins, P. Van Dokkum, Z. Haiman, A. Torralba Torregrosa,
J.J. Matthee, The Astrophysical Journal Letters 1002 (2026).
date_created: 2026-05-10T22:02:15Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-05-11T06:48:33Z
day: '10'
ddc:
- '520'
department:
- _id: ZoHa
- _id: JoMa
doi: 10.3847/2041-8213/ae58a5
external_id:
arxiv:
- '2602.02702'
file:
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date_created: 2026-05-11T06:44:37Z
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intvolume: ' 1002'
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language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
grant_number: '101076224'
name: Young galaxies as tracers and agents of cosmic reionization
publication: The Astrophysical Journal Letters
publication_identifier:
eissn:
- 2041-8213
issn:
- 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Connecting the dots: UV-bright companions of Little Red Dots as Lyman–Werner
sources enabling direct-collapse Black Hole formation'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1002
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21847'
abstract:
- lang: eng
text: Analog quantum simulators provide access to many-body dynamics beyond the
reach of classical computation. However, extracting physical insights from experimental
data is often hindered by measurement noise, limited observables, and incomplete
knowledge of the underlying microscopic model. Here, we develop a machine learning
approach based on a variational autoencoder (VAE) to analyze interference measurements
of tunnel-coupled one-dimensional Bose gases, which realize the sine-Gordon quantum
field theory. Trained in an unsupervised manner, the VAE learns a minimal latent
representation that strongly correlates with the equilibrium control parameter
of the system. Applied to nonequilibrium protocols, the latent space uncovers
signatures of frozen-in solitons following rapid cooling, and reveals anomalous
postquench dynamics not captured by conventional correlation-based methods. These
results demonstrate that generative models can extract physically interpretable
variables directly from noisy and sparse experimental data, providing complementary
probes of equilibrium and nonequilibrium physics in quantum simulators. More broadly,
our work highlights how machine learning can supplement established field-theoretical
techniques, paving the way for scalable, data-driven discovery in quantum many-body
systems.
acknowledgement: "We thank Sebastian Erne and Igor Mazets for helpful discussions
and sharing codes for the transfer matrix sampling. This research was funded in
part by the European Research Council: ERC Advanced Grant “Emergence in Quantum
Physics” (EmQ) under Grant Agreement No. 101097858 and ERC Advanced Grant “Artificial
agency and learning in quantum environments” (QuantAI) under Grant Agreement No.
101055129. This work was also supported by the Austrian Science Fund (FWF) (SFB
BeyondC F7102, 10.55776/F71). G.F.-F. acknowledges the European Research Council
AdG NOQIA; MCIN/AEI [PGC2018-0910.13039/501100011033, CEX2019-000910-S/10.13039/501100011033,
Plan National FIDEUA PID2019-106901GB-I00, Plan National STAMEENA PID2022-139099NB,
I00, project funded by MCIN/AEI/10.13039/501100011033 and by the “European Union
NextGenerationEU/PRTR” (PRTR-C17.I1), FPI]; QUANTERA DYNAMITE PCI2022-132919 under
Grant Agreement No. 101017733; Ministry for Digital Transformation and of Civil
Service of the Spanish Government through the QUANTUM ENIA project call—Quantum
Spain project, and by the European Union through the Recovery, Transformation and
Resilience Plan—NextGenerationEU within the framework of the Digital Spain 2026
Agenda; Fundació Cellex; Fundació Mir-Puig; Generalitat de Catalunya (European Social
Fund FEDER and CERCA program); Barcelona Supercomputing Center MareNostrum (FI-2023-3-0024);
(HORIZON-CL4-2022-QUANTUM-02-SGA PASQuanS2.1, 101113690, EU Horizon 2020 FET-OPEN
OPTOlogic, Grant No. 899794, QU-ATTO, 101168628), EU Horizon Europe Program (This
project has received funding from the European Union's Horizon Europe research and
innovation program under Grant Agreement No. 101080086 NeQST); ICFO Internal “QuantumGaudi”
project. This research was funded in whole or in part by the Austrian Science Fund
(FWF) [10.55776/COE1] through the Cluster of Excellence quantA (Quantum Science
Austria).\r\n\r\nThe views and opinions expressed in this article are however those
of the author(s) only and do not necessarily reflect those of the European Union
or the European Research Council—neither the European Union nor the granting authority
can be held responsible for them."
article_number: '023094'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Frederik Skovbo
full_name: Moller, Frederik Skovbo
id: 43cbcc83-0564-11f0-a935-e37325525859
last_name: Moller
- first_name: Gabriel
full_name: Fernández-Fernández, Gabriel
last_name: Fernández-Fernández
- first_name: Thomas
full_name: Schweigler, Thomas
last_name: Schweigler
- first_name: Paulin
full_name: De Schoulepnikoff, Paulin
last_name: De Schoulepnikoff
- first_name: Jörg
full_name: Schmiedmayer, Jörg
last_name: Schmiedmayer
- first_name: Gorka
full_name: Muñoz-Gil, Gorka
last_name: Muñoz-Gil
citation:
ama: Moller FS, Fernández-Fernández G, Schweigler T, De Schoulepnikoff P, Schmiedmayer
J, Muñoz-Gil G. Learning minimal representations of many-body physics from snapshots
of a quantum simulator. Physical Review Research. 2026;8(2). doi:10.1103/r7pj-gl7r
apa: Moller, F. S., Fernández-Fernández, G., Schweigler, T., De Schoulepnikoff,
P., Schmiedmayer, J., & Muñoz-Gil, G. (2026). Learning minimal representations
of many-body physics from snapshots of a quantum simulator. Physical Review
Research. American Physical Society. https://doi.org/10.1103/r7pj-gl7r
chicago: Moller, Frederik Skovbo, Gabriel Fernández-Fernández, Thomas Schweigler,
Paulin De Schoulepnikoff, Jörg Schmiedmayer, and Gorka Muñoz-Gil. “Learning Minimal
Representations of Many-Body Physics from Snapshots of a Quantum Simulator.” Physical
Review Research. American Physical Society, 2026. https://doi.org/10.1103/r7pj-gl7r.
ieee: F. S. Moller, G. Fernández-Fernández, T. Schweigler, P. De Schoulepnikoff,
J. Schmiedmayer, and G. Muñoz-Gil, “Learning minimal representations of many-body
physics from snapshots of a quantum simulator,” Physical Review Research,
vol. 8, no. 2. American Physical Society, 2026.
ista: Moller FS, Fernández-Fernández G, Schweigler T, De Schoulepnikoff P, Schmiedmayer
J, Muñoz-Gil G. 2026. Learning minimal representations of many-body physics from
snapshots of a quantum simulator. Physical Review Research. 8(2), 023094.
mla: Moller, Frederik Skovbo, et al. “Learning Minimal Representations of Many-Body
Physics from Snapshots of a Quantum Simulator.” Physical Review Research,
vol. 8, no. 2, 023094, American Physical Society, 2026, doi:10.1103/r7pj-gl7r.
short: F.S. Moller, G. Fernández-Fernández, T. Schweigler, P. De Schoulepnikoff,
J. Schmiedmayer, G. Muñoz-Gil, Physical Review Research 8 (2026).
date_created: 2026-05-10T22:02:15Z
date_published: 2026-04-29T00:00:00Z
date_updated: 2026-05-11T06:58:56Z
day: '29'
ddc:
- '530'
department:
- _id: EdHa
doi: 10.1103/r7pj-gl7r
external_id:
arxiv:
- '2509.13821'
file:
- access_level: open_access
checksum: dbfc58e1e176f7b63e0d274eb0d1bffa
content_type: application/pdf
creator: dernst
date_created: 2026-05-11T06:56:58Z
date_updated: 2026-05-11T06:56:58Z
file_id: '21852'
file_name: 2026_PhysicalReviewResearch_Moller.pdf
file_size: 1829628
relation: main_file
success: 1
file_date_updated: 2026-05-11T06:56:58Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Physical Review Research
publication_identifier:
eissn:
- 2643-1564
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning minimal representations of many-body physics from snapshots of a quantum
simulator
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21848'
abstract:
- lang: eng
text: 'Despite the success of mRNA therapeutics, challenges remain in optimizing
immune responses and minimizing side effects. Cell-specific antigen delivery may
help reduce required doses and improve vaccine efficacy. In this study, we report
on a targeted delivery system for mRNA to a specific subset of skin-resident antigen-presenting
cells: Langerhans cells. By functionalizing lipid nanoparticles with a langerin-specific
glycomimetic ligand, we achieve selective mRNA delivery to both murine and human
primary Langerhans cells with minimal off-target uptake, at the same time resulting
in significantly increased mRNA translation. This targeted mRNA delivery not only
enhances antigen presentation and T-cell responses but also enables dose-sparing
and superior antitumor immunity compared with conventional immunization in a B16-OVA
tumor model. Importantly, our platform’s high compatibility with various lipid
nanoparticle formulations offers a flexible and precise tool for skin-directed
mRNA delivery.'
acknowledged_ssus:
- _id: PreCl
acknowledgement: We thank Mareike Rentzsch for her intellectual contributions during
the course of our discussions. We thank Michael Schunn from the Preclinical Facility
of the Institute of Science and Technology Austria for his continuous technical
support. Guarantor of the work is FS. This project was supported by “Seedfinancing”
(P2282679) of the Austrian Federal Ministry of Digital and Economic Affairs and
the Ministry of Climate Action and Energy, handled by the Austrian Wirtschaftsservice,
as well as by...
article_processing_charge: No
article_type: original
author:
- first_name: Klara
full_name: Klein, Klara
last_name: Klein
- first_name: Litty
full_name: Johnson, Litty
last_name: Johnson
- first_name: Ramona
full_name: Rîca, Ramona
last_name: Rîca
- first_name: Mirza
full_name: Sarcevic, Mirza
last_name: Sarcevic
- first_name: Gabriele
full_name: Carta, Gabriele
last_name: Carta
- first_name: Saskia
full_name: Seiser, Saskia
last_name: Seiser
- first_name: Adelheid
full_name: Elbe-Bürger, Adelheid
last_name: Elbe-Bürger
- first_name: Freyja
full_name: Langer, Freyja
id: 3C1BE782-F248-11E8-B48F-1D18A9856A87
last_name: Langer
- first_name: Nowras
full_name: Rahhal, Nowras
last_name: Rahhal
- first_name: Christoph
full_name: Rademacher, Christoph
last_name: Rademacher
- first_name: Robert
full_name: Wawrzinek, Robert
last_name: Wawrzinek
- first_name: Federica
full_name: Quattrone, Federica
last_name: Quattrone
- first_name: Florian
full_name: Sparber, Florian
last_name: Sparber
citation:
ama: 'Klein K, Johnson L, Rîca R, et al. Langerhans cell–targeted mRNA delivery:
A strategy for dose-sparing and enhanced antitumor immunity. Journal of Investigative
Dermatology. doi:10.1016/j.jid.2026.03.026'
apa: 'Klein, K., Johnson, L., Rîca, R., Sarcevic, M., Carta, G., Seiser, S., … Sparber,
F. (n.d.). Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing
and enhanced antitumor immunity. Journal of Investigative Dermatology.
Elsevier. https://doi.org/10.1016/j.jid.2026.03.026'
chicago: 'Klein, Klara, Litty Johnson, Ramona Rîca, Mirza Sarcevic, Gabriele Carta,
Saskia Seiser, Adelheid Elbe-Bürger, et al. “Langerhans Cell–Targeted MRNA Delivery:
A Strategy for Dose-Sparing and Enhanced Antitumor Immunity.” Journal of Investigative
Dermatology. Elsevier, n.d. https://doi.org/10.1016/j.jid.2026.03.026.'
ieee: 'K. Klein et al., “Langerhans cell–targeted mRNA delivery: A strategy
for dose-sparing and enhanced antitumor immunity,” Journal of Investigative
Dermatology. Elsevier.'
ista: 'Klein K, Johnson L, Rîca R, Sarcevic M, Carta G, Seiser S, Elbe-Bürger A,
Langer F, Rahhal N, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. Langerhans
cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced antitumor
immunity. Journal of Investigative Dermatology.'
mla: 'Klein, Klara, et al. “Langerhans Cell–Targeted MRNA Delivery: A Strategy for
Dose-Sparing and Enhanced Antitumor Immunity.” Journal of Investigative Dermatology,
Elsevier, doi:10.1016/j.jid.2026.03.026.'
short: K. Klein, L. Johnson, R. Rîca, M. Sarcevic, G. Carta, S. Seiser, A. Elbe-Bürger,
F. Langer, N. Rahhal, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Journal
of Investigative Dermatology (n.d.).
date_created: 2026-05-10T22:02:16Z
date_published: 2026-04-07T00:00:00Z
date_updated: 2026-05-11T06:07:32Z
day: '07'
department:
- _id: PreCl
doi: 10.1016/j.jid.2026.03.026
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2025.06.25.661517
month: '04'
oa: 1
oa_version: Preprint
publication: Journal of Investigative Dermatology
publication_identifier:
eissn:
- 1523-1747
issn:
- 0022-202X
publication_status: inpress
publisher: Elsevier
scopus_import: '1'
status: public
title: 'Langerhans cell–targeted mRNA delivery: A strategy for dose-sparing and enhanced
antitumor immunity'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...