---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21469'
abstract:
- lang: eng
text: "Terahertz (THz) spectroscopy is a powerful probe of low-energy excitations
in complex materials. Extending it into the nonlinear regime broadens its scope
and can provide valuable insight into interactions among these modes. However,
interpreting nonlinear spectra is challenging because resonant features in this
case do not always reflect intrinsic material dynamics. Here, we study nonlinear
THz-induced Kerr effect in a generic material LaAlO3. After detailed analysis
of temporal oscillations of the Kerr signal, we identify an \U0001D438\U0001D454
Raman mode at 1.1 THz excited through a two-photon process, while two additional
peaks (0.86 and 0.36 THz) arise from phase matching of the near-infrared probe
beam with co- and counterpropagating THz pump fields, mediated by off-resonant
electronic hyperpolarizability. These results demonstrate the crucial role of
kinematic effects in shaping THz-induced Kerr response and establish a framework
for interpreting nonlinear spectroscopies in complex materials."
acknowledgement: Z. A. acknowledges support from the collaborative research project
SFB Q-M&S funded by the Austrian Science Fund (FWF, Grant No. PR1050F8602). S. F. M.
acknowledges support and funding from the Deutsche Forschungsgemeinschaft (DFG,
Grant No. 469405347).
article_number: '106901'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Chao
full_name: Shen, Chao
id: f84c083e-dc8d-11ea-abe3-aaf3d822a8bb
last_name: Shen
- first_name: Maximilian
full_name: Frenzel, Maximilian
last_name: Frenzel
- first_name: Sebastian F.
full_name: Maehrlein, Sebastian F.
last_name: Maehrlein
- first_name: Zhanybek
full_name: Alpichshev, Zhanybek
id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
last_name: Alpichshev
orcid: 0000-0002-7183-5203
citation:
ama: Shen C, Frenzel M, Maehrlein SF, Alpichshev Z. Disentangling electronic and
ionic nonlinear polarization effects in bulk THz Kerr response. Physical Review
Letters. 2026;136(10). doi:10.1103/1c5k-9z82
apa: Shen, C., Frenzel, M., Maehrlein, S. F., & Alpichshev, Z. (2026). Disentangling
electronic and ionic nonlinear polarization effects in bulk THz Kerr response.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/1c5k-9z82
chicago: Shen, Chao, Maximilian Frenzel, Sebastian F. Maehrlein, and Zhanybek Alpichshev.
“Disentangling Electronic and Ionic Nonlinear Polarization Effects in Bulk THz
Kerr Response.” Physical Review Letters. American Physical Society, 2026.
https://doi.org/10.1103/1c5k-9z82.
ieee: C. Shen, M. Frenzel, S. F. Maehrlein, and Z. Alpichshev, “Disentangling electronic
and ionic nonlinear polarization effects in bulk THz Kerr response,” Physical
Review Letters, vol. 136, no. 10. American Physical Society, 2026.
ista: Shen C, Frenzel M, Maehrlein SF, Alpichshev Z. 2026. Disentangling electronic
and ionic nonlinear polarization effects in bulk THz Kerr response. Physical Review
Letters. 136(10), 106901.
mla: Shen, Chao, et al. “Disentangling Electronic and Ionic Nonlinear Polarization
Effects in Bulk THz Kerr Response.” Physical Review Letters, vol. 136,
no. 10, 106901, American Physical Society, 2026, doi:10.1103/1c5k-9z82.
short: C. Shen, M. Frenzel, S.F. Maehrlein, Z. Alpichshev, Physical Review Letters
136 (2026).
corr_author: '1'
date_created: 2026-03-22T23:04:31Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-03-23T13:11:09Z
day: '13'
ddc:
- '530'
department:
- _id: ZhAl
- _id: GradSch
doi: 10.1103/1c5k-9z82
file:
- access_level: open_access
checksum: 712b05b4b0e0fbe9fd426a8c9d41ce20
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T13:08:06Z
date_updated: 2026-03-23T13:08:06Z
file_id: '21475'
file_name: 2026_PhysicalReviewLetters_Shen.pdf
file_size: 1375532
relation: main_file
success: 1
file_date_updated: 2026-03-23T13:08:06Z
has_accepted_license: '1'
intvolume: ' 136'
issue: '10'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 34a97cc6-11ca-11ed-8bc3-9acbba792f33
grant_number: F8602
name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems:
Nonlinear THz spectroscopy of quantum critical materials'
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Disentangling electronic and ionic nonlinear polarization effects in bulk THz
Kerr response
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21470'
abstract:
- lang: eng
text: Despite its pivotal role in optical manipulation, high capacity communications,
and quantum information, a general measure of orbital angular momentum (OAM) in
structured light remains elusive. In optical fields, where multiple vortices coexist,
the local nature of vortex OAM and the absence of a common rotation axis make
the total OAM of the field difficult to quantify. Here, we introduce the R index—a
metric that captures the intrinsic OAM content of any structured optical field,
from pure Laguerre–Gaussian modes to arbitrary multi vortex superpositions. Not
only does this metric quantify the total OAM, it also assesses field purity, providing
insight into the fidelity and robustness of the OAM generation. By unifying OAM
characterization into a single figure of merit, the R index enables direct comparison
across diverse beam profiles and facilitates the identification of optimal configurations
for both foundational studies and applied technologies.
acknowledgement: This research was funded in whole or in part by the Austrian Science
Fund (FWF) [10.55776/F1004]. For open access purposes, the author has applied a
CC BY public copyright license to any author accepted manuscript version arising
from this submission.
article_number: '015071'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Monika
full_name: Bahl, Monika
last_name: Bahl
- first_name: Georgios
full_name: Koutentakis, Georgios
id: d7b23d3a-9e21-11ec-b482-f76739596b95
last_name: Koutentakis
- first_name: Mikhail
full_name: Maslov, Mikhail
id: 2E65BB0E-F248-11E8-B48F-1D18A9856A87
last_name: Maslov
orcid: 0000-0003-4074-2570
- first_name: Tom
full_name: Jungnickel, Tom
last_name: Jungnickel
- first_name: Timo
full_name: Gaßen, Timo
last_name: Gaßen
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
- first_name: Oliver H.
full_name: Heckl, Oliver H.
last_name: Heckl
citation:
ama: 'Bahl M, Koutentakis G, Maslov M, et al. The R-index: A universal metric for
evaluating OAM content and mode purity in optical fields. Journal of Physics:
Photonics. 2026;8(1). doi:10.1088/2515-7647/ae3506'
apa: 'Bahl, M., Koutentakis, G., Maslov, M., Jungnickel, T., Gaßen, T., Lemeshko,
M., & Heckl, O. H. (2026). The R-index: A universal metric for evaluating
OAM content and mode purity in optical fields. Journal of Physics: Photonics.
IOP Publishing. https://doi.org/10.1088/2515-7647/ae3506'
chicago: 'Bahl, Monika, Georgios Koutentakis, Mikhail Maslov, Tom Jungnickel, Timo
Gaßen, Mikhail Lemeshko, and Oliver H. Heckl. “The R-Index: A Universal Metric
for Evaluating OAM Content and Mode Purity in Optical Fields.” Journal of Physics:
Photonics. IOP Publishing, 2026. https://doi.org/10.1088/2515-7647/ae3506.'
ieee: 'M. Bahl et al., “The R-index: A universal metric for evaluating OAM
content and mode purity in optical fields,” Journal of Physics: Photonics,
vol. 8, no. 1. IOP Publishing, 2026.'
ista: 'Bahl M, Koutentakis G, Maslov M, Jungnickel T, Gaßen T, Lemeshko M, Heckl
OH. 2026. The R-index: A universal metric for evaluating OAM content and mode
purity in optical fields. Journal of Physics: Photonics. 8(1), 015071.'
mla: 'Bahl, Monika, et al. “The R-Index: A Universal Metric for Evaluating OAM Content
and Mode Purity in Optical Fields.” Journal of Physics: Photonics, vol.
8, no. 1, 015071, IOP Publishing, 2026, doi:10.1088/2515-7647/ae3506.'
short: 'M. Bahl, G. Koutentakis, M. Maslov, T. Jungnickel, T. Gaßen, M. Lemeshko,
O.H. Heckl, Journal of Physics: Photonics 8 (2026).'
corr_author: '1'
date_created: 2026-03-22T23:04:32Z
date_published: 2026-03-10T00:00:00Z
date_updated: 2026-03-23T13:26:26Z
day: '10'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1088/2515-7647/ae3506
external_id:
arxiv:
- '2508.12973'
file:
- access_level: open_access
checksum: 0ec8a2d3f9efa704203a41f068344974
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T13:24:01Z
date_updated: 2026-03-23T13:24:01Z
file_id: '21476'
file_name: 2026_JPhysPhotonics_Bahl.pdf
file_size: 1150404
relation: main_file
success: 1
file_date_updated: 2026-03-23T13:24:01Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 7c040762-9f16-11ee-852c-dd79eeee4ab3
grant_number: F100403
name: Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions
publication: 'Journal of Physics: Photonics'
publication_identifier:
eissn:
- 2515-7647
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The R-index: A universal metric for evaluating OAM content and mode purity
in optical fields'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21471'
acknowledgement: We thank the Barton group at the Institute of Scienceand Technology
Austria for many fruitful conversationsthat triggered the germination of the ideas
and questions discussed here. N. H. Barton, P. Surendranadh, A. Pal,Z. Mérai, and
two anonymous reviewers provided useful comments on the manuscript.
article_number: e70175
article_processing_charge: No
article_type: letter_note
author:
- first_name: Sofia Maria
full_name: Backlund, Sofia Maria
id: a19ed178-1337-11ed-9389-c30ab879a82a
last_name: Backlund
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Rosina Matilde
full_name: Soler Schaller, Rosina Matilde
id: 9e668447-8c32-11ed-b0c7-8dc2d7b80803
last_name: Soler Schaller
citation:
ama: 'Backlund SM, Stankowski S, Soler Schaller RM. Seeds as space-time travelers:
How does evolution balance the joint benefits and trade-offs of dormancy and dispersal?
American Journal of Botany. 2026;113(3). doi:10.1002/ajb2.70175'
apa: 'Backlund, S. M., Stankowski, S., & Soler Schaller, R. M. (2026). Seeds
as space-time travelers: How does evolution balance the joint benefits and trade-offs
of dormancy and dispersal? American Journal of Botany. Wiley. https://doi.org/10.1002/ajb2.70175'
chicago: 'Backlund, Sofia Maria, Sean Stankowski, and Rosina Matilde Soler Schaller.
“Seeds as Space-Time Travelers: How Does Evolution Balance the Joint Benefits
and Trade-Offs of Dormancy and Dispersal?” American Journal of Botany.
Wiley, 2026. https://doi.org/10.1002/ajb2.70175.'
ieee: 'S. M. Backlund, S. Stankowski, and R. M. Soler Schaller, “Seeds as space-time
travelers: How does evolution balance the joint benefits and trade-offs of dormancy
and dispersal?,” American Journal of Botany, vol. 113, no. 3. Wiley, 2026.'
ista: 'Backlund SM, Stankowski S, Soler Schaller RM. 2026. Seeds as space-time travelers:
How does evolution balance the joint benefits and trade-offs of dormancy and dispersal?
American Journal of Botany. 113(3), e70175.'
mla: 'Backlund, Sofia Maria, et al. “Seeds as Space-Time Travelers: How Does Evolution
Balance the Joint Benefits and Trade-Offs of Dormancy and Dispersal?” American
Journal of Botany, vol. 113, no. 3, e70175, Wiley, 2026, doi:10.1002/ajb2.70175.'
short: S.M. Backlund, S. Stankowski, R.M. Soler Schaller, American Journal of Botany
113 (2026).
corr_author: '1'
date_created: 2026-03-22T23:04:33Z
date_published: 2026-03-11T00:00:00Z
date_updated: 2026-03-23T14:47:52Z
day: '11'
ddc:
- '580'
- '570'
department:
- _id: NiBa
- _id: GradSch
doi: 10.1002/ajb2.70175
external_id:
pmid:
- '41814642'
file:
- access_level: open_access
checksum: 6116108a12c4a5cc91fc653d67885309
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T14:01:44Z
date_updated: 2026-03-23T14:01:44Z
file_id: '21477'
file_name: 2026_AmericanJourBotany_Backlund.pdf
file_size: 495080
relation: main_file
success: 1
file_date_updated: 2026-03-23T14:01:44Z
has_accepted_license: '1'
intvolume: ' 113'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: American Journal of Botany
publication_identifier:
eissn:
- 1537-2197
issn:
- 0002-9122
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Seeds as space-time travelers: How does evolution balance the joint benefits
and trade-offs of dormancy and dispersal?'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 113
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21472'
abstract:
- lang: eng
text: We study the ground state energy of a gas of spin 1/2 fermions with repulsive
short-range interactions. We derive an upper bound that agrees, at low density
e, with the Huang–Yang conjecture. The latter captures the first three terms in
an asymptotic low-density expansion, and in particular the Huang–Yang correction
term of order e^7/3. Our trial state is constructed using an adaptation of the
bosonic Bogoliubov theory to the Fermi system, where the correlation structure
of fermionic particles is incorporated by quasi-bosonic Bogoliubov transformations.
In the latter, it is important to consider a modified zero-energy scattering equation
that takes into account the presence of the Fermi sea, in the spirit of the Bethe–Goldstone
equation.
acknowledgement: "We thank the referees for valuable remarks. This work was partially
funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)
via the TRR 352 – Project-ID 470903074. PTN was partially supported by the European
Research Council via the ERC Consolidator Grant RAMBAS – Project-Nr. 10104424.\r\nOpen
access publishing facilitated by Università degli Studi di Milano, as part of the
Wiley - CRUI-CARE agreement."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Emanuela L.
full_name: Giacomelli, Emanuela L.
last_name: Giacomelli
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Phan Thành
full_name: Nam, Phan Thành
last_name: Nam
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: 'Giacomelli EL, Hainzl C, Nam PT, Seiringer R. The Huang–Yang formula for the
low-density Fermi gas: Upper bound. Communications on Pure and Applied Mathematics.
2026. doi:10.1002/cpa.70040'
apa: 'Giacomelli, E. L., Hainzl, C., Nam, P. T., & Seiringer, R. (2026). The
Huang–Yang formula for the low-density Fermi gas: Upper bound. Communications
on Pure and Applied Mathematics. Wiley. https://doi.org/10.1002/cpa.70040'
chicago: 'Giacomelli, Emanuela L., Christian Hainzl, Phan Thành Nam, and Robert
Seiringer. “The Huang–Yang Formula for the Low-Density Fermi Gas: Upper Bound.”
Communications on Pure and Applied Mathematics. Wiley, 2026. https://doi.org/10.1002/cpa.70040.'
ieee: 'E. L. Giacomelli, C. Hainzl, P. T. Nam, and R. Seiringer, “The Huang–Yang
formula for the low-density Fermi gas: Upper bound,” Communications on Pure
and Applied Mathematics. Wiley, 2026.'
ista: 'Giacomelli EL, Hainzl C, Nam PT, Seiringer R. 2026. The Huang–Yang formula
for the low-density Fermi gas: Upper bound. Communications on Pure and Applied
Mathematics.'
mla: 'Giacomelli, Emanuela L., et al. “The Huang–Yang Formula for the Low-Density
Fermi Gas: Upper Bound.” Communications on Pure and Applied Mathematics,
Wiley, 2026, doi:10.1002/cpa.70040.'
short: E.L. Giacomelli, C. Hainzl, P.T. Nam, R. Seiringer, Communications on Pure
and Applied Mathematics (2026).
date_created: 2026-03-22T23:04:33Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-06-18T08:30:39Z
day: '13'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1002/cpa.70040
external_id:
arxiv:
- '2409.17914'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/cpa.70040
month: '03'
oa: 1
oa_version: Published Version
publication: Communications on Pure and Applied Mathematics
publication_identifier:
eissn:
- 1097-0312
issn:
- 0010-3640
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Huang–Yang formula for the low-density Fermi gas: Upper bound'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21473'
abstract:
- lang: eng
text: Physical exercise acutely improves hippocampus-dependent memory. Whereas animal
studies have offered cellular- and synaptic-level accounts of these effects, human
neuroimaging studies show that exercise improves hippocampal-cortical connectivity
at the macroscale level. However, the neurophysiological basis of exercise-induced
effects on hippocampal-cortical circuits remains unknown. Experimental evidence
supports the idea that hippocampal sharp wave-ripples (SWR) play a critical role
in learning and memory. Coupling between SWRs in the hippocampus and neocortex
may reflect modulations in inter-regional connectivity required by mnemonic processes.
Here, we examine the hypothesis that exercise modulates hippocampal-cortical ripple
dynamics in the human brain. We performed intracranial recordings in epilepsy
patients undergoing pre-surgical evaluation, during awake resting state, before
and after an exercise session. Exercise increased ripple rate in the hippocampus.
Exercise also enhanced the coupling and phase-synchrony between cortical ripples
in the limbic and the default mode (DM) cortical networks and hippocampal SWRs.
Further, a higher heart rate during exercise, reflecting exercise intensity, was
related to a subsequent increase in resting state ripples across specific cortical
networks, including the DM network. These results offer the first direct evidence
that a single exercise session elicits changes in ripple events, a well-established
neurophysiological marker of mnemonic processing. The characterisation and anatomical
distribution of the described modulation points to hippocampal ripples as a potential
mechanism by which exercise elicits its reported short-term effects in cognition.
acknowledgement: We acknowledge the generosity of the patients, who contributed time
and effort to take part in this study.
article_number: fcag041
article_processing_charge: Yes
article_type: original
author:
- first_name: Araceli R.
full_name: Cardenas, Araceli R.
last_name: Cardenas
- first_name: Juan F
full_name: Ramirez Villegas, Juan F
id: 44B06F76-F248-11E8-B48F-1D18A9856A87
last_name: Ramirez Villegas
- first_name: Christopher K.
full_name: Kovach, Christopher K.
last_name: Kovach
- first_name: Phillip E.
full_name: Gander, Phillip E.
last_name: Gander
- first_name: Rachel C.
full_name: Cole, Rachel C.
last_name: Cole
- first_name: Andrew J.
full_name: Grossbach, Andrew J.
last_name: Grossbach
- first_name: Hiroto
full_name: Kawasaki, Hiroto
last_name: Kawasaki
- first_name: Jeremy D.W.
full_name: Greenlee, Jeremy D.W.
last_name: Greenlee
- first_name: Matthew A.
full_name: Howard, Matthew A.
last_name: Howard
- first_name: Kirill V.
full_name: Nourski, Kirill V.
last_name: Nourski
- first_name: Matthew I.
full_name: Banks, Matthew I.
last_name: Banks
- first_name: Michelle W.
full_name: Voss, Michelle W.
last_name: Voss
citation:
ama: Cardenas AR, Ramirez Villegas JF, Kovach CK, et al. Exercise enhances hippocampal-cortical
ripple interactions in the human brain. Brain Communications. 2026;8(2).
doi:10.1093/braincomms/fcag041
apa: Cardenas, A. R., Ramirez Villegas, J. F., Kovach, C. K., Gander, P. E., Cole,
R. C., Grossbach, A. J., … Voss, M. W. (2026). Exercise enhances hippocampal-cortical
ripple interactions in the human brain. Brain Communications. Oxford University
Press. https://doi.org/10.1093/braincomms/fcag041
chicago: Cardenas, Araceli R., Juan F Ramirez Villegas, Christopher K. Kovach, Phillip
E. Gander, Rachel C. Cole, Andrew J. Grossbach, Hiroto Kawasaki, et al. “Exercise
Enhances Hippocampal-Cortical Ripple Interactions in the Human Brain.” Brain
Communications. Oxford University Press, 2026. https://doi.org/10.1093/braincomms/fcag041.
ieee: A. R. Cardenas et al., “Exercise enhances hippocampal-cortical ripple
interactions in the human brain,” Brain Communications, vol. 8, no. 2.
Oxford University Press, 2026.
ista: Cardenas AR, Ramirez Villegas JF, Kovach CK, Gander PE, Cole RC, Grossbach
AJ, Kawasaki H, Greenlee JDW, Howard MA, Nourski KV, Banks MI, Voss MW. 2026.
Exercise enhances hippocampal-cortical ripple interactions in the human brain.
Brain Communications. 8(2), fcag041.
mla: Cardenas, Araceli R., et al. “Exercise Enhances Hippocampal-Cortical Ripple
Interactions in the Human Brain.” Brain Communications, vol. 8, no. 2,
fcag041, Oxford University Press, 2026, doi:10.1093/braincomms/fcag041.
short: A.R. Cardenas, J.F. Ramirez Villegas, C.K. Kovach, P.E. Gander, R.C. Cole,
A.J. Grossbach, H. Kawasaki, J.D.W. Greenlee, M.A. Howard, K.V. Nourski, M.I.
Banks, M.W. Voss, Brain Communications 8 (2026).
corr_author: '1'
date_created: 2026-03-22T23:04:34Z
date_published: 2026-03-09T00:00:00Z
date_updated: 2026-03-23T14:30:47Z
day: '09'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1093/braincomms/fcag041
file:
- access_level: open_access
checksum: b5b45c16defeaf88056fc3b939bd0350
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T14:27:39Z
date_updated: 2026-03-23T14:27:39Z
file_id: '21478'
file_name: 2026_BrainCommunications_Cardenas.pdf
file_size: 33974419
relation: main_file
success: 1
file_date_updated: 2026-03-23T14:27:39Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Brain Communications
publication_identifier:
eissn:
- 2632-1297
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exercise enhances hippocampal-cortical ripple interactions in the human brain
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21480'
abstract:
- lang: eng
text: We present and test a protocol to learn the matrix-product operator (MPO)
representation of an experimentally prepared quantum state. The protocol takes
as input classical shadows corresponding to local randomized measurements, and
outputs the tensors of an MPO maximizing a suitably defined fidelity with the
experimental state. The tensor optimization is carried out sequentially, similarly
to the well-known density matrix renormalization group algorithm. Our approach
is provably efficient under certain technical conditions expected to be met in
short-range correlated states and in typical noisy experimental settings. Under
the same conditions, we also provide an efficient scheme to estimate fidelities
between the learned and the experimental states. We experimentally demonstrate
our protocol by learning entangled quantum states of up to N = 96 qubits in a
superconducting quantum processor. Our method upgrades classical shadows to large-scale
quantum computation and simulation experiments.
acknowledgement: "We acknowledge insightful discussions with Antoine Browaeys, Mari
Carmen Bañuls, Soonwon Choi, Thierry Lahaye, Daniel Stilck-França, Georgios Styliaris,
and Xavier Waintal. The experimental data have been collected using the Qiskit library
[103], and have been postprocessed using the RandomMeas [104] and ITensor [105]
libraries. The work of M. V. and B. V. was funded by the French National Research
Agency via the JCJC project QRand (No. ANR-20-CE47-0005), and via the research programs
Plan France 2030 EPIQ (No. ANR-22-\r\nPETQ-0007), QUBITAF (No. ANR-22-PETQ-0004),
and HQI (No. ANR-22-PNCQ-0002). We acknowledge the use of IBM Quantum Credits for
this work. M. L. acknowledges support by the Deutsche Forschungsgemeinschaft (DFG,
German Research Foundation) under Germany’s Excellence Strategy—EXC-2111–390814868.
The work of C. L. was funded by the French National Research Agency via the PRC
project ESQuisses (No. ANR-20-CE47-0014-01). J. I. C.\r\nacknowledges funding from
the Federal Ministry of Education and Research Germany (BMBF) via the project FermiQP
(No. 13N15889). Work at MPQ is part of the Munich Quantum Valley, which is supported
by the Bavarian state government with funds from the Hightech Agenda\r\nBayern Plus.
P. Z. acknowledges support by the European Union’s Horizon Europe research and innovation
program under Grant Agreement No. 101113690 (PASQANS2). The work of L. P. was funded
by the European Union (ERC, QUANTHEM, No. 101114881). We acknowledge support\r\nby
the Erwin Schrödinger International Institute for Mathematics and Physics (ESI)."
article_number: '090801'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Matteo
full_name: Votto, Matteo
last_name: Votto
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Cécilia
full_name: Lancien, Cécilia
last_name: Lancien
- first_name: J. Ignacio
full_name: Cirac, J. Ignacio
last_name: Cirac
- first_name: Peter
full_name: Zoller, Peter
last_name: Zoller
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Lorenzo
full_name: Piroli, Lorenzo
last_name: Piroli
- first_name: Benoît
full_name: Vermersch, Benoît
last_name: Vermersch
citation:
ama: Votto M, Ljubotina M, Lancien C, et al. Learning mixed quantum states in large-scale
experiments. Physical Review Letters. 2026;136(9). doi:10.1103/rbg2-f61m
apa: Votto, M., Ljubotina, M., Lancien, C., Cirac, J. I., Zoller, P., Serbyn, M.,
… Vermersch, B. (2026). Learning mixed quantum states in large-scale experiments.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/rbg2-f61m
chicago: Votto, Matteo, Marko Ljubotina, Cécilia Lancien, J. Ignacio Cirac, Peter
Zoller, Maksym Serbyn, Lorenzo Piroli, and Benoît Vermersch. “Learning Mixed Quantum
States in Large-Scale Experiments.” Physical Review Letters. American Physical
Society, 2026. https://doi.org/10.1103/rbg2-f61m.
ieee: M. Votto et al., “Learning mixed quantum states in large-scale experiments,”
Physical Review Letters, vol. 136, no. 9. American Physical Society, 2026.
ista: Votto M, Ljubotina M, Lancien C, Cirac JI, Zoller P, Serbyn M, Piroli L, Vermersch
B. 2026. Learning mixed quantum states in large-scale experiments. Physical Review
Letters. 136(9), 090801.
mla: Votto, Matteo, et al. “Learning Mixed Quantum States in Large-Scale Experiments.”
Physical Review Letters, vol. 136, no. 9, 090801, American Physical Society,
2026, doi:10.1103/rbg2-f61m.
short: M. Votto, M. Ljubotina, C. Lancien, J.I. Cirac, P. Zoller, M. Serbyn, L.
Piroli, B. Vermersch, Physical Review Letters 136 (2026).
date_created: 2026-03-23T14:56:32Z
date_published: 2026-03-04T00:00:00Z
date_updated: 2026-03-23T15:39:34Z
day: '04'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/rbg2-f61m
external_id:
arxiv:
- '2507.12550'
file:
- access_level: open_access
checksum: 12b16ce2d49c62b2909da95121bfaadb
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T15:35:27Z
date_updated: 2026-03-23T15:35:27Z
file_id: '21491'
file_name: 2026_PhysicalReviewLetters_Votto.pdf
file_size: 500041
relation: main_file
success: 1
file_date_updated: 2026-03-23T15:35:27Z
has_accepted_license: '1'
intvolume: ' 136'
issue: '9'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Learning mixed quantum states in large-scale experiments
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '21481'
abstract:
- lang: eng
text: 'The Hα emission line in galaxies is a powerful tracer of their recent star
formation activity. With the advent of JWST, we are now able to routinely observe
Hα in galaxies at high redshift (z ≳ 3) and thus measure their star formation
rates (SFRs). However, using classical SFR(Hα) calibrations to derive the SFRs
leads to biased results because high-redshift galaxies are commonly characterized
by low metallicities and bursty star formation histories, affecting the conversion
factor between the Hα luminosity (LHα) and the SFR. We developed a set of new
SFR(Hα) calibrations that allowed us to predict the SFRs of Hα-emitters at z ≳ 3
with very little error. We used the SPHINX cosmological simulations to select
a sample of star-forming galaxies representative of the Hα-emitter population
observed with JWST. We then derived linear corrections to the classical SFR(Hα)
calibrations that took variations in the physical properties (e.g., stellar metallicities)
among individual galaxies into account. We obtained two new SFR(Hα) calibrations
that compared to the classical calibrations reduce the root mean squared error
(RMSE) in the predicted SFRs by ΔRMSE ≈ 0.04 dex and ΔRMSE ≈ 0.06 dex, respectively.
Using the recent JWST NIRCam/grism observations of Hα-emitters at z ∼ 6, we show
that the new calibrations affect the high-redshift galaxy population statistics:
(i) the estimated cosmic SFR density decreases by ΔρSFR ≈ 12%, and (ii) the observed
slope of the star formation main sequence increases by Δ∂logSFR/∂logM★ = 0.08 ± 0.02.'
acknowledgement: "We thank the anonymous referee for the insightful comments that
helped improve the manuscript. We also thank Thibault Garel, Pascal Oesch, Irene
Shivaei, Charlotte Simmonds, Andrew Hopkins, Daniel Schaerer, and Rashmi Gottumukkala
for useful comments and productive discussions. We gratefully acknowledge support
from the CBPsmn (PSMN, Pôle Scientifique de Modélisation Numérique) of the ENS de
Lyon for the computing resources.\r\nFunded by the European Union (ERC, AGENTS,
101076224). Views and opinions expressed are however those of the author(s) only
and do not necessarily reflect those of the European Union or the European Research
Council. Neither the European Union nor the granting authority can be held responsible
for them. This work made extensive use of several open-source software packages,
and we gratefully acknowledge the efforts of their authors: numpy (Harris et al.
2020), astropy (Astropy Collaboration 2022), matplotlib (Hunter 2007), ipython (Perez
& Granger 2007), and scikit-learn (Pedregosa et al. 2011)."
article_number: A184
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Ivan
full_name: Kramarenko, Ivan
id: 9a9394cb-3200-11ee-973b-f5ba2a8b16e4
last_name: Kramarenko
orcid: 0000-0001-5346-6048
- first_name: J.
full_name: Rosdahl, J.
last_name: Rosdahl
- first_name: J.
full_name: Blaizot, J.
last_name: Blaizot
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: H.
full_name: Katz, H.
last_name: Katz
- first_name: Claudia
full_name: Di Cesare, Claudia
id: 2d002343-372f-11ef-98ec-a164d20427cb
last_name: Di Cesare
citation:
ama: Kramarenko I, Rosdahl J, Blaizot J, Matthee JJ, Katz H, Di Cesare C. H α as
a tracer of star formation in the SPHINX cosmological simulations. Astronomy
& Astrophysics. 2026;707. doi:10.1051/0004-6361/202557114
apa: Kramarenko, I., Rosdahl, J., Blaizot, J., Matthee, J. J., Katz, H., & Di
Cesare, C. (2026). H α as a tracer of star formation in the SPHINX cosmological
simulations. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202557114
chicago: Kramarenko, Ivan, J. Rosdahl, J. Blaizot, Jorryt J Matthee, H. Katz, and
Claudia Di Cesare. “H α as a Tracer of Star Formation in the SPHINX Cosmological
Simulations.” Astronomy & Astrophysics. EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202557114.
ieee: I. Kramarenko, J. Rosdahl, J. Blaizot, J. J. Matthee, H. Katz, and C. Di Cesare,
“H α as a tracer of star formation in the SPHINX cosmological simulations,” Astronomy
& Astrophysics, vol. 707. EDP Sciences, 2026.
ista: Kramarenko I, Rosdahl J, Blaizot J, Matthee JJ, Katz H, Di Cesare C. 2026.
H α as a tracer of star formation in the SPHINX cosmological simulations. Astronomy
& Astrophysics. 707, A184.
mla: Kramarenko, Ivan, et al. “H α as a Tracer of Star Formation in the SPHINX Cosmological
Simulations.” Astronomy & Astrophysics, vol. 707, A184, EDP Sciences,
2026, doi:10.1051/0004-6361/202557114.
short: I. Kramarenko, J. Rosdahl, J. Blaizot, J.J. Matthee, H. Katz, C. Di Cesare,
Astronomy & Astrophysics 707 (2026).
corr_author: '1'
date_created: 2026-03-23T14:58:03Z
date_published: 2026-03-05T00:00:00Z
date_updated: 2026-03-23T15:46:31Z
day: '05'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1051/0004-6361/202557114
external_id:
arxiv:
- '2509.05403'
file:
- access_level: open_access
checksum: 7429076b381dd498084f40ffd199e714
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T15:44:09Z
date_updated: 2026-03-23T15:44:09Z
file_id: '21492'
file_name: 2026_AstronomyAstrophysics_Kramarenko.pdf
file_size: 904565
relation: main_file
success: 1
file_date_updated: 2026-03-23T15:44:09Z
has_accepted_license: '1'
intvolume: ' 707'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
grant_number: '101076224'
name: Young galaxies as tracers and agents of cosmic reionization
publication: Astronomy & Astrophysics
publication_identifier:
eissn:
- 1432-0746
issn:
- 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
status: public
title: H α as a tracer of star formation in the SPHINX cosmological simulations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 707
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21482'
abstract:
- lang: eng
text: Controlling the size and shape of assembled structures is a fundamental challenge
in self-assembly and is highly relevant in material design and biology. Here,
we show that specific but promiscuous short-range binding interactions make it
possible to economically assemble linear filaments of user-defined length. Our
approach leads to independent control over the mean and width of the filament
size distribution and allows us to smoothly explore design trade-offs between
assembly quality (spread in size) and cost (number of particle species). We employ
a simple hierarchical assembly protocol to minimize assembly times and show that
multiple stages of hierarchy make it possible to extend our approach to the assembly
of higher-dimensional structures. Our work provides a conceptually simple solution
to size control that is applicable to a broad range of systems, from DNA nanoparticles
to supramolecular polymers and beyond.
acknowledgement: We thank Maitane Muñoz-Basagoiti for helpful discussions. The research
was supported by the Gesellschaft für Forschungsförderung Niederösterreich under
Project No. FTI23-G-011.
article_number: L012054
article_processing_charge: Yes
article_type: original
author:
- first_name: Maximilian
full_name: Hübl, Maximilian
id: 5eb8629e-15b2-11ec-abd3-e6f3e5e01f32
last_name: Hübl
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
citation:
ama: Hübl M, Goodrich CP. Entropic size control of self-assembled filaments. Physical
Review Research. 2026;8. doi:10.1103/68rs-3qgn
apa: Hübl, M., & Goodrich, C. P. (2026). Entropic size control of self-assembled
filaments. Physical Review Research. American Physical Society. https://doi.org/10.1103/68rs-3qgn
chicago: Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled
Filaments.” Physical Review Research. American Physical Society, 2026.
https://doi.org/10.1103/68rs-3qgn.
ieee: M. Hübl and C. P. Goodrich, “Entropic size control of self-assembled filaments,”
Physical Review Research, vol. 8. American Physical Society, 2026.
ista: Hübl M, Goodrich CP. 2026. Entropic size control of self-assembled filaments.
Physical Review Research. 8, L012054.
mla: Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled
Filaments.” Physical Review Research, vol. 8, L012054, American Physical
Society, 2026, doi:10.1103/68rs-3qgn.
short: M. Hübl, C.P. Goodrich, Physical Review Research 8 (2026).
corr_author: '1'
date_created: 2026-03-23T14:58:31Z
date_published: 2026-03-05T00:00:00Z
date_updated: 2026-03-23T15:59:11Z
day: '05'
ddc:
- '530'
department:
- _id: CaGo
- _id: GradSch
doi: 10.1103/68rs-3qgn
file:
- access_level: open_access
checksum: 6d8a68e4a19f8dad5abdf75f72316f3d
content_type: application/pdf
creator: dernst
date_created: 2026-03-23T15:53:29Z
date_updated: 2026-03-23T15:53:29Z
file_id: '21493'
file_name: 2026_PhysicalReviewResearch_Huebl.pdf
file_size: 2680924
relation: main_file
success: 1
file_date_updated: 2026-03-23T15:53:29Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 8dd93da8-16d5-11f0-9cad-d2c70200d9a5
grant_number: FTI23-G-011
name: Dynamically reconfigurable self-assembly with triangular DNA-origami bricks
publication: Physical Review Research
publication_identifier:
eissn:
- 2643-1564
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Entropic size control of self-assembled filaments
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21483'
abstract:
- lang: eng
text: 'Embryogenesis in the model plant Arabidopsis thaliana provides a framework
for understanding how cell polarity and patterning coordinate with hormonal signalling
to establish the plant body plan. Following fertilisation, the zygote divides
asymmetrically to generate apical and basal lineages, establishing the apical–basal
axis that defines future shoot and root poles. Genetic and molecular analyses
of classical mutants including gnom, monopteros (mp), bodenlos (bdl) and topless
revealed that localised auxin biosynthesis, directional transport and downstream
transcriptional responses are central to apical–basal axis establishment and organ
initiation. The main components of this regulation are polarly localised PIN auxin
transporters and downstream modules involving MONOPTEROS and WUSCHEL-RELATED HOMEOBOX
transcription factors. Advances in microscopy have transformed the study of Arabidopsis
embryogenesis: fluorescence-compatible clearing reagents and three-dimensional
reconstructions now permit quantitative analyses of cell geometry, division orientation,
and cytoskeletal dynamics. Live ovule imaging setups with confocal laser scanning
and multiphoton microscopes enable real-time observation of embryo development,
while laser-assisted cell ablation can be used to probe cell-to-cell communication
and fate plasticity. Together, these methodological breakthroughs position Arabidopsis
embryos as a prime model for dissecting the chemical and biophysical cues that
shape plant development.'
acknowledgement: The authors would like to acknowledge the many colleagues whose valuable
contributions to the field could not be included in this review due to space limitations
and reference constraints. Open Access funding provided by Institute of Science
and Technology Austria/KEMÖ.
article_number: nph.71072
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: David
full_name: Babic, David
id: db566d23-f6e0-11ea-865d-e6f270e968e7
last_name: Babic
- first_name: Milan
full_name: Zupunski, Milan
id: f6a21fce-573e-11f0-a150-a8d96aee2539
last_name: Zupunski
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Babic D, Zupunski M, Friml J. Imaging and genetic toolbox to study Arabidopsis
embryogenesis. New Phytologist. 2026. doi:10.1111/nph.71072
apa: Babic, D., Zupunski, M., & Friml, J. (2026). Imaging and genetic toolbox
to study Arabidopsis embryogenesis. New Phytologist. Wiley. https://doi.org/10.1111/nph.71072
chicago: Babic, David, Milan Zupunski, and Jiří Friml. “Imaging and Genetic Toolbox
to Study Arabidopsis Embryogenesis.” New Phytologist. Wiley, 2026. https://doi.org/10.1111/nph.71072.
ieee: D. Babic, M. Zupunski, and J. Friml, “Imaging and genetic toolbox to study
Arabidopsis embryogenesis,” New Phytologist. Wiley, 2026.
ista: Babic D, Zupunski M, Friml J. 2026. Imaging and genetic toolbox to study Arabidopsis
embryogenesis. New Phytologist., nph. 71072.
mla: Babic, David, et al. “Imaging and Genetic Toolbox to Study Arabidopsis Embryogenesis.”
New Phytologist, nph. 71072, Wiley, 2026, doi:10.1111/nph.71072.
short: D. Babic, M. Zupunski, J. Friml, New Phytologist (2026).
corr_author: '1'
date_created: 2026-03-23T14:59:06Z
date_published: 2026-03-11T00:00:00Z
date_updated: 2026-06-18T08:31:45Z
day: '11'
ddc:
- '580'
department:
- _id: JiFr
- _id: GradSch
doi: 10.1111/nph.71072
external_id:
pmid:
- '41808651'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/nph.71072
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: New Phytologist
publication_identifier:
eissn:
- 1469-8137
issn:
- 0028-646X
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
status: public
title: Imaging and genetic toolbox to study Arabidopsis embryogenesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21484'
abstract:
- lang: eng
text: An individual's phenotype reflects a complex interplay of the direct effects
of their DNA, epigenetic modifications of their DNA induced by their parents,
and indirect effects of their parents' DNA. Here, we derive how the genetic variance
within a population is changed under the influence of indirect maternal, paternal
and parent-of-origin effects under random mating. We also consider indirect effects
of a sibling, in particular how the genetic variance is altered when looking at
the phenotypic difference between two siblings. The calculations are then extended
to include assortative mating (AM), which alters the variance by inducing increased
homozygosity and correlations within and across loci. AM likely leads to covariance
of parental genetic effects, a measure of the similarity of parents in the indirect
effects they have on their children. We propose that this assortment for parental
characteristics, where biological parents create similar environments for their
children, can create shared parental effects across traits and the appearance
of cross-trait AM. Our theory shows how the resemblance among relatives increases
under both AM, indirect and parent-of-origin effects. When our model is used to
predict correlations among relatives in human height, we find that explaining
the patterns observed in real data requires both indirect genetic effects and
assortative mating. The degree to which direct, indirect and epigenetic effects
shape the phenotypic variance of complex traits remains an open question that
requires large-scale family data to be resolved.
acknowledgement: We thank members of the Medical Genomics group at ISTA for their
comments, which improved this manuscript. This work was funded by an SNSF Eccellenza
Grant to MRR (PCEGP3-181181), and by core funding from the Institute of Science
and Technology Austria.
article_number: iyag042
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Ilse
full_name: Krätschmer, Ilse
id: 30d4014e-7753-11eb-b44b-db6d61112e73
last_name: Krätschmer
orcid: 0000-0002-5636-9259
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
citation:
ama: Krätschmer I, Robinson MR. A quantitative genetic model for indirect genetic
effects and genomic imprinting under random and assortative mating. Genetics.
2026. doi:10.1093/genetics/iyag042
apa: Krätschmer, I., & Robinson, M. R. (2026). A quantitative genetic model
for indirect genetic effects and genomic imprinting under random and assortative
mating. Genetics. Oxford University Press. https://doi.org/10.1093/genetics/iyag042
chicago: Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic
Model for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative
Mating.” Genetics. Oxford University Press, 2026. https://doi.org/10.1093/genetics/iyag042.
ieee: I. Krätschmer and M. R. Robinson, “A quantitative genetic model for indirect
genetic effects and genomic imprinting under random and assortative mating,” Genetics.
Oxford University Press, 2026.
ista: Krätschmer I, Robinson MR. 2026. A quantitative genetic model for indirect
genetic effects and genomic imprinting under random and assortative mating. Genetics.,
iyag042.
mla: Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic Model
for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative
Mating.” Genetics, iyag042, Oxford University Press, 2026, doi:10.1093/genetics/iyag042.
short: I. Krätschmer, M.R. Robinson, Genetics (2026).
corr_author: '1'
date_created: 2026-03-23T15:02:54Z
date_published: 2026-02-12T00:00:00Z
date_updated: 2026-06-18T08:31:14Z
day: '12'
ddc:
- '570'
department:
- _id: MaRo
doi: 10.1093/genetics/iyag042
external_id:
pmid:
- '41677404'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/genetics/iyag042
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 1943-2631
publication_status: epub_ahead
publisher: Oxford University Press
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/medical-genomics-group/familyMC
status: public
title: A quantitative genetic model for indirect genetic effects and genomic imprinting
under random and assortative mating
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21485'
abstract:
- lang: eng
text: Insulating oxides are among the most abundant solid materials in the universe1,2,3.
Of the many ways in which they influence natural phenomena, perhaps the most consequential
is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which
occurs even between samples of the same oxide—yet the symmetry-breaking parameter
that causes this remains unidentified11,12. Here we show that adventitious carbonaceous
molecules adsorbed from the environment are the symmetry-breaking factor in same-material
oxide contact electrification (CE). We use acoustic levitation to measure charge
exchange between a sphere and a plate composed of identical amorphous silicon
dioxide (SiO2). Although charging polarity is random for co-prepared samples,
we control it with baking or plasma treatment. Observing the charge-exchange relaxation
afterwards, we see dynamics over a timescale of hours and connect this directly
to the presence of adventitious carbon with time-of-flight mass spectrometry,
low-energy ion scattering and infrared spectroscopy. Going further, we confirm
that adventitious carbon can even determine charge exchange among different oxides.
Our results identify the symmetry-breaking parameter that causes insulating oxides
to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6,
while simultaneously highlighting an overlooked factor in CE more broadly.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: LifeSc
acknowledgement: This project has received support from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
(grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant
agreement no. 754411). We acknowledge the state of Lower Austria and the European
Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges
support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research
was supported by the Scientific Service Units of the Institute of Science and Technology
Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility,
Scientific Computing facility and Lab Support Facility. We thank the Modic group
for the use of the Laue camera, T. Zauner for the photography of the experimental
set-up and R. Möller for insightful discussions. Open access funding provided by
Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Galien M
full_name: Grosjean, Galien M
id: 0C5FDA4A-9CF6-11E9-8939-FF05E6697425
last_name: Grosjean
orcid: 0000-0001-5154-417X
- first_name: Markus
full_name: Ostermann, Markus
last_name: Ostermann
- first_name: Markus
full_name: Sauer, Markus
last_name: Sauer
- first_name: Michael
full_name: Hahn, Michael
last_name: Hahn
- first_name: Christian M.
full_name: Pichler, Christian M.
last_name: Pichler
- first_name: Florian
full_name: Fahrnberger, Florian
last_name: Fahrnberger
- first_name: Felix
full_name: Pertl, Felix
id: 6313aec0-15b2-11ec-abd3-ed67d16139af
last_name: Pertl
orcid: 0000-0003-0463-5794
- first_name: Daniel
full_name: Balazs, Daniel
id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
last_name: Balazs
orcid: 0000-0001-7597-043X
- first_name: Mason M.
full_name: Link, Mason M.
last_name: Link
- first_name: Seong H.
full_name: Kim, Seong H.
last_name: Kim
- first_name: Devin L.
full_name: Schrader, Devin L.
last_name: Schrader
- first_name: Adriana
full_name: Blanco, Adriana
last_name: Blanco
- first_name: Francisco
full_name: Gracia, Francisco
last_name: Gracia
- first_name: Nicolás
full_name: Mujica, Nicolás
last_name: Mujica
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
citation:
ama: Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry
in oxide contact electrification. Nature. 2026;651(8106):626-631. doi:10.1038/s41586-025-10088-w
apa: Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger,
F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide
contact electrification. Nature. Springer Nature. https://doi.org/10.1038/s41586-025-10088-w
chicago: Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian
M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks
Symmetry in Oxide Contact Electrification.” Nature. Springer Nature, 2026.
https://doi.org/10.1038/s41586-025-10088-w.
ieee: G. M. Grosjean et al., “Adventitious carbon breaks symmetry in oxide
contact electrification,” Nature, vol. 651, no. 8106. Springer Nature,
pp. 626–631, 2026.
ista: Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl
F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis
SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification.
Nature. 651(8106), 626–631.
mla: Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact
Electrification.” Nature, vol. 651, no. 8106, Springer Nature, 2026, pp.
626–31, doi:10.1038/s41586-025-10088-w.
short: G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger,
F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia,
N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631.
corr_author: '1'
date_created: 2026-03-23T15:04:00Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-28T12:06:01Z
day: '18'
ddc:
- '540'
department:
- _id: ScWa
- _id: GradSch
- _id: LifeSc
doi: 10.1038/s41586-025-10088-w
ec_funded: 1
external_id:
pmid:
- '41851325'
file:
- access_level: open_access
checksum: dafef9ed575b44be4263e948a47ae056
content_type: application/pdf
creator: dernst
date_created: 2026-03-24T06:57:08Z
date_updated: 2026-03-24T06:57:08Z
file_id: '21494'
file_name: 2026_Nature_Grosjean.pdf
file_size: 12245694
relation: main_file
success: 1
file_date_updated: 2026-03-24T06:57:08Z
has_accepted_license: '1'
intvolume: ' 651'
issue: '8106'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 626-631
pmid: 1
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
call_identifier: H2020
grant_number: '949120'
name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: press_release
url: https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/
status: public
title: Adventitious carbon breaks symmetry in oxide contact electrification
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 651
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21486'
abstract:
- lang: eng
text: Sex-chromosome systems are highly variable across animals, but how they transition
from one to another is not well understood. Diptera have undergone multiple sex-chromosome
turnovers and expansions while maintaining their general chromosomal content,
which makes them an ideal clade to study such transitions. We analyzed more than
100 dipteran whole-genome assemblies and identified 4 new lineages that underwent
sex-chromosome turnover (in addition to the 5 previously reported). We find that
the majority of turnovers happened in the group Schizophora, which tend to have
fewer genes on Muller element F (the chromosome homologous to the ancestral insect
X chromosome) than lower dipterans, a factor previously hypothesized to facilitate
turnover. Most derived X chromosomes have higher GC content than autosomes, consistent
with a high prevalence of male achiasmy in Diptera. In addition, an excess of
gene movement out of the X is detected for most of these new X chromosomes, and
many of these moved genes have high testis expression in Drosophila, suggesting
that out-of-X gene movement contributes to the long-term demasculinization of
X chromosomes.
acknowledgement: This work was supported by a grant from the Austrian Science Fund
(FWF, grant number PAT 8748323) to B.V. We thank the Vicoso group for their feedback
on an early version of the manuscript. We are grateful to Kamil Jaron and Julia
Gries for helpful discussions and for sharing their unpublished work. Computational
resources and support were provided by the Scientific Computing Unit at ISTA.
article_number: qrag003
article_processing_charge: Yes
article_type: original
author:
- first_name: Lorena Alexandra
full_name: Layana Franco, Lorena Alexandra
id: 02814589-eb8f-11eb-b029-a70074f3f18f
last_name: Layana Franco
orcid: 0000-0002-1253-6297
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: Layana Franco LA, Toups MA, Vicoso B. Causes and consequences of sex-chromosome
turnovers in Diptera. Evolution Letters. 2026. doi:10.1093/evlett/qrag003
apa: Layana Franco, L. A., Toups, M. A., & Vicoso, B. (2026). Causes and consequences
of sex-chromosome turnovers in Diptera. Evolution Letters. Oxford University
Press. https://doi.org/10.1093/evlett/qrag003
chicago: Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Causes
and Consequences of Sex-Chromosome Turnovers in Diptera.” Evolution Letters.
Oxford University Press, 2026. https://doi.org/10.1093/evlett/qrag003.
ieee: L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Causes and consequences
of sex-chromosome turnovers in Diptera,” Evolution Letters. Oxford University
Press, 2026.
ista: Layana Franco LA, Toups MA, Vicoso B. 2026. Causes and consequences of sex-chromosome
turnovers in Diptera. Evolution Letters., qrag003.
mla: Layana Franco, Lorena Alexandra, et al. “Causes and Consequences of Sex-Chromosome
Turnovers in Diptera.” Evolution Letters, qrag003, Oxford University Press,
2026, doi:10.1093/evlett/qrag003.
short: L.A. Layana Franco, M.A. Toups, B. Vicoso, Evolution Letters (2026).
corr_author: '1'
date_created: 2026-03-23T15:05:42Z
date_published: 2026-03-12T00:00:00Z
date_updated: 2026-03-24T07:14:08Z
day: '12'
ddc:
- '570'
department:
- _id: BeVi
- _id: GradSch
doi: 10.1093/evlett/qrag003
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/evlett/qrag003
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 8ed82125-16d5-11f0-9cad-fbcae312235b
grant_number: PAT 8748323
name: Sex chromosomes in evolution and development
publication: Evolution Letters
publication_identifier:
eissn:
- 2056-3744
publication_status: epub_ahead
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: Causes and consequences of sex-chromosome turnovers in Diptera
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21488'
abstract:
- lang: eng
text: Human height is a model for the genetic analysis of complex traits, and recent
studies suggest the presence of thousands of common genetic variant associations
and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic
paradigm based on approximate message passing (genomic vector approximate message
passing [gVAMP]) for identifying DNA sequence variants associated with complex
traits and common diseases in large-scale whole-genome sequencing (WGS) data.
We show that gVAMP accurately localizes associations to variants with the correct
frequency and position in the DNA, outperforming existing fine-mapping methods
in selecting the appropriate genetic variants within WGS data. We then apply gVAMP
to jointly model the relationship of tens of millions of WGS variants with human
height in hundreds of thousands of UK Biobank individuals. We identify 59 rare
variants and gene burden scores alongside many hundreds of DNA regions containing
common variant associations and show that understanding the genetic basis of complex
traits will require the joint analysis of hundreds of millions of variables measured
on millions of people. The polygenic risk scores obtained from gVAMP have high
accuracy (including a prediction accuracy of ∼46% for human height) and outperform
current methods for downstream tasks such as mixed linear model association testing
across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation
for a wider range of analyses in WGS data.
acknowledgement: We thank Malgorzata Borczyk for creating the gene burden scores.
We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter,
Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for
providing valuable suggestions and comments on earlier versions of the work. This
project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to
M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364),
and core funding from ISTA. High-performance computing was supported by the Scientific
Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).
We would like to acknowledge the participants and investigators of the UK Biobank
study. We gratefully acknowledge the All of Us participants for their contributions,
without whom this research would not have been possible. We also thank the National
Institutes of Health All of Us Research Program for making available the participant
data (and/or samples and/or cohort) examined in this study.
article_number: '101162'
article_processing_charge: Yes
article_type: original
author:
- first_name: Al
full_name: Depope, Al
id: 0b77531d-dbcd-11ea-9d1d-a8eee0bf3830
last_name: Depope
- first_name: Jakub
full_name: Bajzik, Jakub
id: b995e25b-8c4b-11ed-a6d8-f71b7bcd6122
last_name: Bajzik
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
citation:
ama: Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome
sequencing data for human height via approximate message passing. Cell Genomics.
2026. doi:10.1016/j.xgen.2026.101162
apa: Depope, A., Bajzik, J., Mondelli, M., & Robinson, M. R. (2026). Joint modeling
of whole-genome sequencing data for human height via approximate message passing.
Cell Genomics. Elsevier. https://doi.org/10.1016/j.xgen.2026.101162
chicago: Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson.
“Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate
Message Passing.” Cell Genomics. Elsevier, 2026. https://doi.org/10.1016/j.xgen.2026.101162.
ieee: A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of
whole-genome sequencing data for human height via approximate message passing,”
Cell Genomics. Elsevier, 2026.
ista: Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome
sequencing data for human height via approximate message passing. Cell Genomics.,
101162.
mla: Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human
Height via Approximate Message Passing.” Cell Genomics, 101162, Elsevier,
2026, doi:10.1016/j.xgen.2026.101162.
short: A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics (2026).
corr_author: '1'
date_created: 2026-03-23T15:10:03Z
date_published: 2026-02-18T00:00:00Z
date_updated: 2026-04-28T12:08:37Z
day: '18'
ddc:
- '000'
- '570'
department:
- _id: MaMo
- _id: MaRo
doi: 10.1016/j.xgen.2026.101162
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.xgen.2026.101162
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
name: Prix Lopez-Loretta 2019 - Marco Mondelli
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
grant_number: '101161364'
name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
grant_number: PCEGP3_181181
name: Improving estimation and prediction of common complex disease risk
publication: Cell Genomics
publication_identifier:
eissn:
- 2666-979X
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: press_release
url: https://ista.ac.at/en/news/big-data-and-human-height/
status: public
title: Joint modeling of whole-genome sequencing data for human height via approximate
message passing
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2026'
...
---
_id: '21489'
abstract:
- lang: eng
text: We study Kirillov algebras attached to minuscule highest weight representations
of semisimple Lie algebras. They can be viewed as equivariant cohomology algebras
of partial flag varieties. Real structures on the varieties then induce involutions
of these algebras. We describe how these involutions act on the spectra of minuscule
Kirillov algebras, and model the fixed points via the equivariant cohomology of
real partial flag varieties. We then use this model to characterise freeness of
the fixed point coordinate ring over the appropriate base. As an application,
we recover a q = -1 phenomenon of Stembridge in the minuscule case by geometric
means.
acknowledgement: 'I would like to thank Tamás Hausel for introducing me to this area
of mathematics and for his constant guidance. I would also like to thank Jakub Löwit
and Miguel González for fruitful discussions and many helpful comments on this paper.
This work was done during the author’s PhD studies at the Institute of Science and
Technology Austria (ISTA). It was funded by the Austrian Science Fund (FWF) 10.55776/P35847.
Open access funding provided by Institute of Science and Technology (IST Austria). '
article_processing_charge: Yes (via OA deal)
arxiv: 1
author:
- first_name: Mischa M
full_name: Elkner, Mischa M
id: 477faa59-080d-11ed-979a-c693ab7638ab
last_name: Elkner
citation:
ama: Elkner MM. On involutions of minuscule Kirillov algebras induced by real structures.
Transformation Groups. 2026. doi:10.1007/s00031-026-09958-y
apa: Elkner, M. M. (2026). On involutions of minuscule Kirillov algebras induced
by real structures. Transformation Groups. Springer Nature. https://doi.org/10.1007/s00031-026-09958-y
chicago: Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced
by Real Structures.” Transformation Groups. Springer Nature, 2026. https://doi.org/10.1007/s00031-026-09958-y.
ieee: M. M. Elkner, “On involutions of minuscule Kirillov algebras induced by real
structures,” Transformation Groups. Springer Nature, 2026.
ista: Elkner MM. 2026. On involutions of minuscule Kirillov algebras induced by
real structures. Transformation Groups.
mla: Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by
Real Structures.” Transformation Groups, Springer Nature, 2026, doi:10.1007/s00031-026-09958-y.
short: M.M. Elkner, Transformation Groups (2026).
corr_author: '1'
date_created: 2026-03-23T15:10:43Z
date_published: 2026-03-14T00:00:00Z
date_updated: 2026-03-24T08:26:10Z
day: '14'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1007/s00031-026-09958-y
external_id:
arxiv:
- '2411.16270'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s00031-026-09958-y
month: '03'
oa: 1
oa_version: None
project:
- _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3
grant_number: P35847
name: Geometry of the tip of the global nilpotent cone
publication: Transformation Groups
publication_identifier:
eissn:
- 1531-586X
issn:
- 1083-4362
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On involutions of minuscule Kirillov algebras induced by real structures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21490'
abstract:
- lang: eng
text: Auxin canalization is a self-organizing process that governs the flexible
formation of vasculature by reinforcing the formation of auxin transport channels.
A key prerequisite is the feedback between auxin signaling and directional auxin
transport, mediated by PIN transporters. Despite the developmental importance
of canalization, the molecular components linking auxin perception to the regulation
of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel
and essential component of auxin canalization that links intracellular auxin signaling
with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23
transcriptional auxin signaling. tow mutants exhibit defects in regeneration and
de novo vasculature formation, along with impaired formation of polarized, PIN-expressing
auxin channels. At the subcellular level, these mutants display disrupted auxin-induced
PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes
predominantly to the plasma membrane, where it interacts with receptor-like kinases
involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR
complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at
the cell surface. Together, our findings identify TOW as a molecular link between
intracellular and cell surface auxin signaling mechanisms that converge on PIN
trafficking and polarity, providing new insights into how auxin signaling regulates
directional auxin transport for the self-organizing formation of vasculature during
flexible plant development.
acknowledged_ssus:
- _id: MassSpec
- _id: Bio
- _id: LifeSc
acknowledgement: We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9
system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof.
Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions,
and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also
acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging
& Optics Facility, and the Lab Support Facility at the Institute of Science and
Technology Austria. This research was supported by the Scientific Service Units
(SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF)
and the Lab Support Facility (LSF). The work conducted by the Friml group was funded
by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS)
and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the
core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant
Sciences Core Facility of CEITEC Masaryk University. E.M. received support from
the National Science Centre (NCN), Poland, through the OPUS call within the Weave
programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next
GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes
Amos Comenius.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Mingyue
full_name: Li, Mingyue
id: 01f96916-0235-11eb-9379-a323192643b7
last_name: Li
- first_name: Nikola
full_name: Rydza, Nikola
last_name: Rydza
- first_name: Ewa
full_name: Mazur, Ewa
last_name: Mazur
- first_name: Gergely
full_name: Molnar, Gergely
id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
last_name: Molnar
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization. Current Biology.
2026;36(6):1468-1480.e6. doi:10.1016/j.cub.2026.02.023
apa: Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., & Friml, J. (2026).
Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin
canalization. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2026.02.023
chicago: Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński,
and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters
for Auxin Canalization.” Current Biology. Elsevier, 2026. https://doi.org/10.1016/j.cub.2026.02.023.
ieee: M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization,” Current Biology,
vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026.
ista: Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting
protein TOW stabilizes PIN transporters for auxin canalization. Current Biology.
36(6), 1468–1480.e6.
mla: Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes
PIN Transporters for Auxin Canalization.” Current Biology, vol. 36, no.
6, Elsevier, 2026, p. 1468–1480.e6, doi:10.1016/j.cub.2026.02.023.
short: M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology
36 (2026) 1468–1480.e6.
corr_author: '1'
date_created: 2026-03-23T15:11:16Z
date_published: 2026-03-23T00:00:00Z
date_updated: 2026-03-24T08:36:40Z
day: '23'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.cub.2026.02.023
external_id:
pmid:
- '41831441'
file:
- access_level: open_access
checksum: fe6c41fdab58a55df5f2a5860c02acdc
content_type: application/pdf
creator: dernst
date_created: 2026-03-24T08:34:37Z
date_updated: 2026-03-24T08:34:37Z
file_id: '21496'
file_name: 2026_CurrentBiology_Li.pdf
file_size: 12986894
relation: main_file
success: 1
file_date_updated: 2026-03-24T08:34:37Z
has_accepted_license: '1'
intvolume: ' 36'
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1468-1480.e6
pmid: 1
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
grant_number: '101142681'
name: Cyclic nucleotides as second messengers in plants
- _id: bd906599-d553-11ed-ba76-abf8547645d7
grant_number: E271
name: Identification of a novel regulator in auxin canalization
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for
auxin canalization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21501'
abstract:
- lang: eng
text: "Kinetically constrained models were originally introduced to capture slow
relaxation in glassy systems, where dynamics are hindered by local constraints
instead of energy barriers. Their quantum counterparts have recently drawn attention
for exhibiting highly degenerate eigenstates at zero energy—known as zero modes—stemming
from chiral symmetry. Yet, the structure and implications of these zero modes
remain poorly understood. In this work, we focus on the properties of the zero
mode subspace in quantum kinetically constrained models with a U(1) particle-conservation
symmetry. We use the U(1) East, which lacks inversion symmetry, and the inversion-symmetric
U(1) East-West models to illustrate our two main results. First, we observe that
the simultaneous presence of constraints and chiral symmetry generally leads to
a parametric increase in the number of zero modes due to the fragmentation of
the many-body\r\nHilbert space into disconnected sectors. Second, we generalize
the concept of compact localized states from single-particle physics and introduce
the notion of collective bound states, a special kind of nonergodic eigenstates
that are robust to enlarging the system size. We formulate sufficient criteria
for their existence, arguing that the degenerate zero mode subspace plays a central
role, and demonstrate bound states in both example models and in a two-dimensional
model, the U(1) North-East, and in the pairflip model, a system without particle
conservation. Our results motivate a systematic study of bound states and their
relation to ergodicity breaking, transport, and other properties of quantum kinetically
constrained\r\nmodels. "
acknowledgement: The authors acknowledge useful discussions with Berislav Buca. This
work was supported by the European Research Council (ERC) under the European Union’s
Horizon 2020 research and innovation program (Grant Agreement No. 850899). M.L.
acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research
Foundation) under Germany’s Excellence Strategy—EXC-2111—390814868. This research
was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical
Physics (KITP).
article_number: '010352'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Eulalia
full_name: Nicolau Jimenez, Eulalia
id: 04b4791c-8fd7-11ee-a7df-be2fdc569c48
last_name: Nicolau Jimenez
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Nicolau Jimenez E, Ljubotina M, Serbyn M. Fragmentation, zero modes, and collective
bound states in constrained models. PRX Quantum. 2026;7. doi:10.1103/sl79-1xgb
apa: Nicolau Jimenez, E., Ljubotina, M., & Serbyn, M. (2026). Fragmentation,
zero modes, and collective bound states in constrained models. PRX Quantum.
American Physical Society. https://doi.org/10.1103/sl79-1xgb
chicago: Nicolau Jimenez, Eulalia, Marko Ljubotina, and Maksym Serbyn. “Fragmentation,
Zero Modes, and Collective Bound States in Constrained Models.” PRX Quantum.
American Physical Society, 2026. https://doi.org/10.1103/sl79-1xgb.
ieee: E. Nicolau Jimenez, M. Ljubotina, and M. Serbyn, “Fragmentation, zero modes,
and collective bound states in constrained models,” PRX Quantum, vol. 7.
American Physical Society, 2026.
ista: Nicolau Jimenez E, Ljubotina M, Serbyn M. 2026. Fragmentation, zero modes,
and collective bound states in constrained models. PRX Quantum. 7, 010352.
mla: Nicolau Jimenez, Eulalia, et al. “Fragmentation, Zero Modes, and Collective
Bound States in Constrained Models.” PRX Quantum, vol. 7, 010352, American
Physical Society, 2026, doi:10.1103/sl79-1xgb.
short: E. Nicolau Jimenez, M. Ljubotina, M. Serbyn, PRX Quantum 7 (2026).
corr_author: '1'
date_created: 2026-03-28T14:57:56Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-03-30T06:09:28Z
day: '13'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/sl79-1xgb
ec_funded: 1
external_id:
arxiv:
- '2504.17627'
file:
- access_level: open_access
checksum: d155ffa9e1a8275702149165f4bf963c
content_type: application/pdf
creator: dernst
date_created: 2026-03-30T06:08:07Z
date_updated: 2026-03-30T06:08:07Z
file_id: '21505'
file_name: 2026_PRXQuantum_Nicolau.pdf
file_size: 1848724
relation: main_file
success: 1
file_date_updated: 2026-03-30T06:08:07Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: PRX Quantum
publication_identifier:
eissn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fragmentation, zero modes, and collective bound states in constrained models
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21502'
abstract:
- lang: eng
text: The mammalian brain stores glucose, the main circulating energy substrate,
as glycogen. In rodents, the cerebellum contains relatively high glycogen levels,
yet its cellular and subcellular distribution remains poorly defined. Using monoclonal
antibodies against glycogen, we examined its distribution in the mouse cerebellar
cortex. Glycogen was predominantly localized to Bergmann glia (BG) processes in
the molecular layer and was also detected in Purkinje cells (PCs), the principal
cerebellar neurons. To assess the functional significance of cerebellar glycogen,
we analyzed behavior in mice lacking glycogen synthase 1 (Gys1) in BG or PCs using
a floxed Gys1 line. Gys1 deficiency in either PCs or GFAP-positive cells reduced
anxiety-like behavior, whereas combined deletion caused PC degeneration and ataxia.
These findings reveal a critical role for glycogen metabolism in both astrocytes
and neurons in cerebellar function.
acknowledgement: This work was supported by the Novo Nordisk Foundation (NNFOC0058058,
H. Hirase), the Danmarks Frie Forskningsfond (0134-00107B and 5283-00069A, H.Hirase),
the Lundbeck Foundation, Japan Society for the Promotion of Science Grants-in-Aid
for Scientific Research (KAKENHI) program (22K06454/24H01221, A.K.; 23K27482, H.Hirai),
the Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated
Neurotechnologies for Disease Studies (Brain/MINDS) (JP21dm0207111, H. Hirai), AMED
Brain/MINDS 2.0 (JP23wm0625001 and JP24wm0625103, H. Hirai), and grants from the
Spanish Ministerio de Ciencia e Innovación (MCIU/FEDER/AEI) (PID2020-118699 GB-100,
J.D.) and the Fundación Ramón Areces (J.D.). Sonam Akther has been supported by
the RIKEN IPA fellowship. We are thankful to Dr. Yuki Oe for his support in the
initial stage of this study and to Dan Xue for his help with the graphical abstract.
We thank Dr. Pia Weikop for providing CTN research infrastructure. The authors declare
no competing financial interests.
article_number: '115192'
article_processing_charge: Yes
article_type: original
author:
- first_name: Sonam
full_name: Akther, Sonam
last_name: Akther
- first_name: Ashley Bomin
full_name: Lee, Ashley Bomin
last_name: Lee
- first_name: Ayumu
full_name: Konno, Ayumu
last_name: Konno
- first_name: Antonis
full_name: Asiminas, Antonis
last_name: Asiminas
- first_name: Marta
full_name: Vittani, Marta
last_name: Vittani
- first_name: Tsuneko
full_name: Mishima, Tsuneko
last_name: Mishima
- first_name: Hirokazu
full_name: Hirai, Hirokazu
last_name: Hirai
- first_name: Claire Francesca
full_name: Meehan, Claire Francesca
last_name: Meehan
- first_name: Jordi
full_name: Duran, Jordi
last_name: Duran
- first_name: Joan
full_name: Guinovart, Joan
last_name: Guinovart
- first_name: Hitoshi
full_name: Ashida, Hitoshi
last_name: Ashida
- first_name: Tsuyoshi
full_name: Morita, Tsuyoshi
last_name: Morita
- first_name: Otto
full_name: Baba, Otto
last_name: Baba
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Maiken
full_name: Nedergaard, Maiken
last_name: Nedergaard
- first_name: Hajime
full_name: Hirase, Hajime
last_name: Hirase
citation:
ama: Akther S, Lee AB, Konno A, et al. Distribution and functional significance
of rodent cerebellar glycogen. iScience. 2026;29(4). doi:10.1016/j.isci.2026.115192
apa: Akther, S., Lee, A. B., Konno, A., Asiminas, A., Vittani, M., Mishima, T.,
… Hirase, H. (2026). Distribution and functional significance of rodent cerebellar
glycogen. IScience. Elsevier. https://doi.org/10.1016/j.isci.2026.115192
chicago: Akther, Sonam, Ashley Bomin Lee, Ayumu Konno, Antonis Asiminas, Marta Vittani,
Tsuneko Mishima, Hirokazu Hirai, et al. “Distribution and Functional Significance
of Rodent Cerebellar Glycogen.” IScience. Elsevier, 2026. https://doi.org/10.1016/j.isci.2026.115192.
ieee: S. Akther et al., “Distribution and functional significance of rodent
cerebellar glycogen,” iScience, vol. 29, no. 4. Elsevier, 2026.
ista: Akther S, Lee AB, Konno A, Asiminas A, Vittani M, Mishima T, Hirai H, Meehan
CF, Duran J, Guinovart J, Ashida H, Morita T, Baba O, Shigemoto R, Nedergaard
M, Hirase H. 2026. Distribution and functional significance of rodent cerebellar
glycogen. iScience. 29(4), 115192.
mla: Akther, Sonam, et al. “Distribution and Functional Significance of Rodent Cerebellar
Glycogen.” IScience, vol. 29, no. 4, 115192, Elsevier, 2026, doi:10.1016/j.isci.2026.115192.
short: S. Akther, A.B. Lee, A. Konno, A. Asiminas, M. Vittani, T. Mishima, H. Hirai,
C.F. Meehan, J. Duran, J. Guinovart, H. Ashida, T. Morita, O. Baba, R. Shigemoto,
M. Nedergaard, H. Hirase, IScience 29 (2026).
date_created: 2026-03-29T22:07:07Z
date_published: 2026-03-17T00:00:00Z
date_updated: 2026-06-18T08:32:22Z
day: '17'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1016/j.isci.2026.115192
external_id:
pmid:
- '41890976'
intvolume: ' 29'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.isci.2026.115192
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: iScience
publication_identifier:
eissn:
- 2589-0042
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distribution and functional significance of rodent cerebellar glycogen
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21503'
abstract:
- lang: eng
text: Currently, pharmacogenetics relies on partially annotated star alleles, leaving
novel variants and complex haplotypes uninterpretable. Computational scoring frameworks
could overcome these limitations. Here, we comprehensively evaluated the ability
of existing (CADD, FATHMM-XF, PROVEAN, MutationAssessor, SIFT, PhyloP100, APF,
APF2) and novel (PharmGScore and PharmMLScore) variant effect predictors to assess
pharmacogenetic alleles in multiple scenarios. Altogether we analyzed 541 PharmVar
alleles, high‑throughput CYP2C9 and CYP2C19 mutational maps, and 200 642 UK Biobank
exomes linked with health records containing antidepressant treatment outcomes.
Many evaluated tools, especially ensemble frameworks, matched or exceeded star
allele classifications (ROC‑AUC up to 0.85 for allele definitions, 0.95 in vitro;
TPR up to 0.99 for exomes) and accurately predicted severe antidepressant adverse
events for carriers of deleterious variants in CYP2C19 (OR 1.20–1.35). Our findings
show that computational predictors deliver star allele accuracy while overcoming
their limitations. With additional validation, computational tools could enhance
clinical decision frameworks by enabling continuous scoring, incorporating previously
unknown variants, and providing genome-wide applicability.
acknowledgement: "This research has been conducted using the UK Biobank Resource under
Application Number 62979. We are grateful to the UK Biobank and all its voluntary
participants. This work used data provided by patients and collected by the NHS
as part of their care and support.\r\n\r\nThis study was funded by the National
Science Center, Poland: PRELUDIUM BIS-3 grant no. 2021/43/O/NZ7/01187 (development
and benchmarking of variant scores) and SONATINA 5 grant 2021/40/C/NZ2/00218 (UKB
analyses). Additional support came from the statutory funds of the Maj Institute
of Pharmacology PAS. We gratefully acknowledge Poland’s high-performance Infrastructure
PLGrid ACK Cyfronet AGH, for providing computer facilities and support within computational
grant no PLG/2022/015861. DMF and GEB were funded by NIH grants NIH R35GM152106
and UM1HG011969."
article_number: '8'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jacek
full_name: Hajto, Jacek
last_name: Hajto
- first_name: Marcin
full_name: Piechota, Marcin
last_name: Piechota
- first_name: Ilse
full_name: Krätschmer, Ilse
id: 30d4014e-7753-11eb-b44b-db6d61112e73
last_name: Krätschmer
orcid: 0000-0002-5636-9259
- first_name: Paula
full_name: Konowalska, Paula
last_name: Konowalska
- first_name: Gabriel E.
full_name: Boyle, Gabriel E.
last_name: Boyle
- first_name: Douglas M.
full_name: Fowler, Douglas M.
last_name: Fowler
- first_name: Malgorzata
full_name: Borczyk, Malgorzata
last_name: Borczyk
- first_name: Michal
full_name: Korostynski, Michal
last_name: Korostynski
citation:
ama: 'Hajto J, Piechota M, Krätschmer I, et al. Computational variant predictors
for pharmacogenomics: From evaluation of single alleles to assessment of adverse
drug reactions to antidepressants. Pharmacogenomics Journal. 2026;26(2).
doi:10.1038/s41397-026-00399-0'
apa: 'Hajto, J., Piechota, M., Krätschmer, I., Konowalska, P., Boyle, G. E., Fowler,
D. M., … Korostynski, M. (2026). Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants.
Pharmacogenomics Journal. Springer Nature. https://doi.org/10.1038/s41397-026-00399-0'
chicago: 'Hajto, Jacek, Marcin Piechota, Ilse Krätschmer, Paula Konowalska, Gabriel
E. Boyle, Douglas M. Fowler, Malgorzata Borczyk, and Michal Korostynski. “Computational
Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to
Assessment of Adverse Drug Reactions to Antidepressants.” Pharmacogenomics
Journal. Springer Nature, 2026. https://doi.org/10.1038/s41397-026-00399-0.'
ieee: 'J. Hajto et al., “Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants,”
Pharmacogenomics Journal, vol. 26, no. 2. Springer Nature, 2026.'
ista: 'Hajto J, Piechota M, Krätschmer I, Konowalska P, Boyle GE, Fowler DM, Borczyk
M, Korostynski M. 2026. Computational variant predictors for pharmacogenomics:
From evaluation of single alleles to assessment of adverse drug reactions to antidepressants.
Pharmacogenomics Journal. 26(2), 8.'
mla: 'Hajto, Jacek, et al. “Computational Variant Predictors for Pharmacogenomics:
From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.”
Pharmacogenomics Journal, vol. 26, no. 2, 8, Springer Nature, 2026, doi:10.1038/s41397-026-00399-0.'
short: J. Hajto, M. Piechota, I. Krätschmer, P. Konowalska, G.E. Boyle, D.M. Fowler,
M. Borczyk, M. Korostynski, Pharmacogenomics Journal 26 (2026).
date_created: 2026-03-29T22:07:08Z
date_published: 2026-03-09T00:00:00Z
date_updated: 2026-03-30T07:10:50Z
day: '09'
ddc:
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department:
- _id: MaRo
doi: 10.1038/s41397-026-00399-0
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intvolume: ' 26'
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month: '03'
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oa_version: Published Version
pmid: 1
publication: Pharmacogenomics Journal
publication_identifier:
eissn:
- 1473-1150
issn:
- ' 1470-269X'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Computational variant predictors for pharmacogenomics: From evaluation of
single alleles to assessment of adverse drug reactions to antidepressants'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
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volume: 26
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21504'
abstract:
- lang: eng
text: Selecting an appropriate divergence measure is a critical aspect of machine
learning, as it directly impacts model performance. Among the most widely used,
we find the Kullback–Leibler (KL) divergence, originally introduced in kinetic
theory as a measure of relative entropy between probability distributions. Just
as in machine learning, the ability to quantify the proximity of probability distributions
plays a central role in kinetic theory. In this paper, we present a comparative
review of divergence measures rooted in kinetic theory, highlighting their theoretical
foundations and exploring their potential applications in machine learning and
artificial intelligence.
acknowledgement: "This work has been written within the activities of GNCS and GNFM
groups of INdAM (Italian\r\nNational Institute of High Mathematics). G.B. has been
funded by the European Union’s Horizon 2020 research and innovation programme under
the Marie Sklodowska-Curie grant agreement No 101034413. P.G. has been funded by
the European Union - NextGenerationEU, in the framework of the GRINSGrowing Resilient,
INclusive and Sustainable (GRINS PE00000018)."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Gennaro
full_name: Auricchio, Gennaro
last_name: Auricchio
- first_name: Giovanni
full_name: Brigati, Giovanni
id: 63ff57e8-1fbb-11ee-88f2-f558ffc59cf1
last_name: Brigati
- first_name: Paolo
full_name: Giudici, Paolo
last_name: Giudici
- first_name: Giuseppe
full_name: Toscani, Giuseppe
last_name: Toscani
citation:
ama: 'Auricchio G, Brigati G, Giudici P, Toscani G. From kinetic theory to AI: A
rediscovery of high-dimensional divergences and their properties. Mathematical
Models and Methods in Applied Sciences. 2026. doi:10.1142/S0218202526410010'
apa: 'Auricchio, G., Brigati, G., Giudici, P., & Toscani, G. (2026). From kinetic
theory to AI: A rediscovery of high-dimensional divergences and their properties.
Mathematical Models and Methods in Applied Sciences. World Scientific Publishing.
https://doi.org/10.1142/S0218202526410010'
chicago: 'Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani.
“From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and
Their Properties.” Mathematical Models and Methods in Applied Sciences.
World Scientific Publishing, 2026. https://doi.org/10.1142/S0218202526410010.'
ieee: 'G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “From kinetic theory
to AI: A rediscovery of high-dimensional divergences and their properties,” Mathematical
Models and Methods in Applied Sciences. World Scientific Publishing, 2026.'
ista: 'Auricchio G, Brigati G, Giudici P, Toscani G. 2026. From kinetic theory to
AI: A rediscovery of high-dimensional divergences and their properties. Mathematical
Models and Methods in Applied Sciences.'
mla: 'Auricchio, Gennaro, et al. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional
Divergences and Their Properties.” Mathematical Models and Methods in Applied
Sciences, World Scientific Publishing, 2026, doi:10.1142/S0218202526410010.'
short: G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and
Methods in Applied Sciences (2026).
date_created: 2026-03-29T22:07:08Z
date_published: 2026-03-14T00:00:00Z
date_updated: 2026-03-30T06:56:35Z
day: '14'
department:
- _id: JaMa
doi: 10.1142/S0218202526410010
ec_funded: 1
external_id:
arxiv:
- '2507.11387'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2507.11387
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
publication: Mathematical Models and Methods in Applied Sciences
publication_identifier:
eissn:
- 1793-6314
issn:
- 0218-2025
publication_status: epub_ahead
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'From kinetic theory to AI: A rediscovery of high-dimensional divergences and
their properties'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21509'
abstract:
- lang: eng
text: Chromatin remodeling complexes mobilize nucleosomes and promote transcription
factor (TF) binding. Using ensemble and single-molecule assays combined with cryo-electron
microscopy (cryo-EM), we studied the interaction between pioneer TFs OCT4–SOX2
and the human BRG1/BRM-associated factor (BAF) complex on nucleosomes. BAF engages
TF-bound substrates in two orientations, placing OCT4–SOX2 at either the remodeler
ENTRY or EXIT site. At the ENTRY site, OCT4–SOX2 initially coexists with BAF without
structural interference. However, continued DNA translocation is expected to cause
collisions with bound TFs, which can trigger remodeling direction reversals or
may induce TF dissociation. To accommodate TFs at the EXIT site, BAF undergoes
structural rearrangements, and ensemble assays reveal a nucleosome subpopulation
translocating away from TF-binding sites. Moreover, single-molecule experiments
show that nucleosome-bound BAF frequently changes remodeling direction, and we
identify an ADP-bound remodeler conformation as a potential intermediate. Together,
these findings reveal key aspects of the conformational dynamics and remodeling
outcomes underlying BAF processing of TF-bound nucleosomes.
acknowledgement: We thank D. Hess, V. Iesmantavicius, and J. Seebacher (FMI Proteomics
and Protein Analysis Facility) for mass spectrometry support; S. Smallwood, K. Shimada,
D. Klein, and M. Schütz-Stoffregen for technical assistance; J. Côté and C. Lachance
for critical discussions; and members of the Thomä lab for helpful feedback. Support
for this work was provided to N.H.T. by the European Research Council under the
European Union’s Horizon 2020 research program (NucEM, no. 884331), the Novartis
Research Foundation, the Swiss National Science Foundation (SNF 31003A_179541, 310030_214852,
and Sinergia CRSII5_186230), and the Swiss Cancer Research (KFS-4980-02-2020 and
KFS-5933-08-2023). S.D. was supported by the European Research Council (DONUTS,
no. 101092623), the Knut and Alice Wallenberg Foundation (2024.0012), the Cancerfonden
(25 4453 Pj), and the Swedish Research Council (VR 03255). A.K.M. was supported
by a Human Frontier Science Program Long-Term Fellowship, and L.V. was supported
by an EMBO fellowship (ALTF 549-2021).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Joscha
full_name: Weiss, Joscha
last_name: Weiss
- first_name: Luca
full_name: Vecchia, Luca
last_name: Vecchia
- first_name: David
full_name: Domjan, David
last_name: Domjan
- first_name: Simone
full_name: Cavadini, Simone
last_name: Cavadini
- first_name: Anton
full_name: Sabantsev, Anton
last_name: Sabantsev
- first_name: Georg
full_name: Kempf, Georg
last_name: Kempf
- first_name: Ganesh R.
full_name: Pathare, Ganesh R.
last_name: Pathare
- first_name: Klaus
full_name: Brackmann, Klaus
last_name: Brackmann
- first_name: Alicia
full_name: Michael, Alicia
id: 6437c950-2a03-11ee-914d-d6476dd7b75c
last_name: Michael
orcid: 0000-0002-6080-839X
- first_name: Lukas
full_name: Kater, Lukas
last_name: Kater
- first_name: Eric
full_name: Hietter-Pfeiffer, Eric
last_name: Hietter-Pfeiffer
- first_name: Mina
full_name: Haddawi, Mina
last_name: Haddawi
- first_name: Urja P.
full_name: Kuber, Urja P.
last_name: Kuber
- first_name: Sandra
full_name: Mühlhäusser, Sandra
last_name: Mühlhäusser
- first_name: Ralph S.
full_name: Grand, Ralph S.
last_name: Grand
- first_name: Michael B.
full_name: Stadler, Michael B.
last_name: Stadler
- first_name: Sebastian
full_name: Deindl, Sebastian
last_name: Deindl
- first_name: Nicolas H.
full_name: Thomä, Nicolas H.
last_name: Thomä
citation:
ama: Weiss J, Vecchia L, Domjan D, et al. The human BAF chromatin remodeler processes
nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular Cell.
2026;86(4):625-639.e8. doi:10.1016/j.molcel.2026.01.021
apa: Weiss, J., Vecchia, L., Domjan, D., Cavadini, S., Sabantsev, A., Kempf, G.,
… Thomä, N. H. (2026). The human BAF chromatin remodeler processes nucleosomes
bound by pioneer transcription factors OCT4–SOX2. Molecular Cell. Elsevier.
https://doi.org/10.1016/j.molcel.2026.01.021
chicago: Weiss, Joscha, Luca Vecchia, David Domjan, Simone Cavadini, Anton Sabantsev,
Georg Kempf, Ganesh R. Pathare, et al. “The Human BAF Chromatin Remodeler Processes
Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” Molecular Cell.
Elsevier, 2026. https://doi.org/10.1016/j.molcel.2026.01.021.
ieee: J. Weiss et al., “The human BAF chromatin remodeler processes nucleosomes
bound by pioneer transcription factors OCT4–SOX2,” Molecular Cell, vol.
86, no. 4. Elsevier, p. 625–639.e8, 2026.
ista: Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR,
Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser
S, Grand RS, Stadler MB, Deindl S, Thomä NH. 2026. The human BAF chromatin remodeler
processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular
Cell. 86(4), 625–639.e8.
mla: Weiss, Joscha, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes
Bound by Pioneer Transcription Factors OCT4–SOX2.” Molecular Cell, vol.
86, no. 4, Elsevier, 2026, p. 625–639.e8, doi:10.1016/j.molcel.2026.01.021.
short: J. Weiss, L. Vecchia, D. Domjan, S. Cavadini, A. Sabantsev, G. Kempf, G.R.
Pathare, K. Brackmann, A.K. Michael, L. Kater, E. Hietter-Pfeiffer, M. Haddawi,
U.P. Kuber, S. Mühlhäusser, R.S. Grand, M.B. Stadler, S. Deindl, N.H. Thomä, Molecular
Cell 86 (2026) 625–639.e8.
date_created: 2026-03-30T11:58:48Z
date_published: 2026-02-19T00:00:00Z
date_updated: 2026-03-30T12:09:08Z
day: '19'
ddc:
- '570'
department:
- _id: AlMi
doi: 10.1016/j.molcel.2026.01.021
external_id:
pmid:
- '41679301'
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- access_level: open_access
checksum: e16a7315b64a706184b177ea1621523c
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page: 625-639.e8
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publication: Molecular Cell
publication_identifier:
issn:
- 1097-2765
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription
factors OCT4–SOX2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 86
year: '2026'
...