--- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19846' abstract: - lang: eng text: The Ca2+-release-activated Ca2+ (CRAC) channel Orai1 is activated by interaction with the Ca2+ sensor Stromal Interaction Molecule 1 (STIM1). Owing to the lack of structurally resolved Orai1/STIM1 complexes, the impact of their coupling on individual Orai1 transmembrane domain (TM) movements is unclear. This study investigates STIM1-independent and STIM1-dependent Orai1-TM dynamics using photocrosslinking unnatural amino acids (UAAs) at each individual TM position. We primarily identify CRAC-channel-like currents directly after UAA incorporation or additional UV-light irradiation at TM3 sites that interface with non-pore-lining TMs. Using UAAs combined with conventional site-directed mutagenesis and molecular dynamics simulations, we discover that pore opening involves a widening of interfaces formed by TM3 with non-pore-lining TMs. Orai1 mutants with a UAA in TM3 exhibit weaker STIM1-induced activation after UV exposure, possibly caused by a restricted widening of non-pore-lining TM interfaces. We demonstrate that photocrosslinking UAAs are excellent tools for improving our understanding of key determinants and ion channel dynamics modulating pore opening. acknowledgement: We thank S. Buchegger for excellent technical assistance. This research was funded by the Austrian Science Fund (FWF) projects https://doi.org/10.55776/P32851, https://doi.org/10.55776/P35900, and https://doi.org/10.55776/P36202 to I.D. and https://doi.org/10.55776/PAT6871323 to A.T. N.M. is funded within the DOC program of the OeAW (Austrian Academy of Science). For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. article_number: '102623' article_processing_charge: Yes article_type: original author: - first_name: Hadil full_name: Najjar, Hadil last_name: Najjar - first_name: Sarah full_name: Weiß, Sarah last_name: Weiß - first_name: Ferdinand full_name: Horvath, Ferdinand id: b0dc7f61-21a3-11ef-a9b4-e6ab1aa6f21e last_name: Horvath - first_name: Valentina full_name: Hopl, Valentina last_name: Hopl - first_name: Adéla full_name: Tiffner, Adéla last_name: Tiffner - first_name: Lorenz full_name: Höbarth, Lorenz last_name: Höbarth - first_name: Julia full_name: Söllner, Julia last_name: Söllner - first_name: Maximilian full_name: Fröhlich, Maximilian last_name: Fröhlich - first_name: Magdalena full_name: Prantl, Magdalena last_name: Prantl - first_name: Nora full_name: Müller, Nora last_name: Müller - first_name: Yuliia full_name: Nazarenko, Yuliia last_name: Nazarenko - first_name: Selina full_name: Harant, Selina last_name: Harant - first_name: Lukas full_name: Weissenböck, Lukas last_name: Weissenböck - first_name: Herwig full_name: Grabmayr, Herwig last_name: Grabmayr - first_name: Matthias full_name: Sallinger, Matthias last_name: Sallinger - first_name: Lena full_name: Maltan, Lena last_name: Maltan - first_name: Linda V. full_name: Echefu, Linda V. last_name: Echefu - first_name: Tamara full_name: Radiskovic, Tamara last_name: Radiskovic - first_name: Melanie full_name: Leopold, Melanie last_name: Leopold - first_name: Sonja full_name: Lindinger, Sonja last_name: Lindinger - first_name: Christina full_name: Humer, Christina last_name: Humer - first_name: Carmen full_name: Höglinger, Carmen last_name: Höglinger - first_name: Heinrich full_name: Krobath, Heinrich last_name: Krobath - first_name: Thomas full_name: Renger, Thomas last_name: Renger - first_name: Isabella full_name: Derler, Isabella last_name: Derler citation: ama: Najjar H, Weiß S, Horvath F, et al. STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening. Cell Reports Physical Science. 2025;6(6). doi:10.1016/j.xcrp.2025.102623 apa: Najjar, H., Weiß, S., Horvath, F., Hopl, V., Tiffner, A., Höbarth, L., … Derler, I. (2025). STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening. Cell Reports Physical Science. Elsevier. https://doi.org/10.1016/j.xcrp.2025.102623 chicago: Najjar, Hadil, Sarah Weiß, Ferdinand Horvath, Valentina Hopl, Adéla Tiffner, Lorenz Höbarth, Julia Söllner, et al. “STIM1-Induced Widening of Non-Pore-Lining TM Interfaces Is Crucial for Orai1 Pore Opening.” Cell Reports Physical Science. Elsevier, 2025. https://doi.org/10.1016/j.xcrp.2025.102623. ieee: H. Najjar et al., “STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening,” Cell Reports Physical Science, vol. 6, no. 6. Elsevier, 2025. ista: Najjar H, Weiß S, Horvath F, Hopl V, Tiffner A, Höbarth L, Söllner J, Fröhlich M, Prantl M, Müller N, Nazarenko Y, Harant S, Weissenböck L, Grabmayr H, Sallinger M, Maltan L, Echefu LV, Radiskovic T, Leopold M, Lindinger S, Humer C, Höglinger C, Krobath H, Renger T, Derler I. 2025. STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening. Cell Reports Physical Science. 6(6), 102623. mla: Najjar, Hadil, et al. “STIM1-Induced Widening of Non-Pore-Lining TM Interfaces Is Crucial for Orai1 Pore Opening.” Cell Reports Physical Science, vol. 6, no. 6, 102623, Elsevier, 2025, doi:10.1016/j.xcrp.2025.102623. short: H. Najjar, S. Weiß, F. Horvath, V. Hopl, A. Tiffner, L. Höbarth, J. Söllner, M. Fröhlich, M. Prantl, N. Müller, Y. Nazarenko, S. Harant, L. Weissenböck, H. Grabmayr, M. Sallinger, L. Maltan, L.V. Echefu, T. Radiskovic, M. Leopold, S. Lindinger, C. Humer, C. Höglinger, H. Krobath, T. Renger, I. Derler, Cell Reports Physical Science 6 (2025). date_created: 2025-06-15T22:01:31Z date_published: 2025-06-18T00:00:00Z date_updated: 2025-09-30T12:53:15Z day: '18' ddc: - '570' department: - _id: AnSa doi: 10.1016/j.xcrp.2025.102623 external_id: isi: - '001516570500009' file: - access_level: open_access checksum: 37ff7c396f966d0ec363e4691d63d402 content_type: application/pdf creator: dernst date_created: 2025-06-23T10:20:22Z date_updated: 2025-06-23T10:20:22Z file_id: '19868' file_name: 2025_CellReportsPhysicalScience_Najjar.pdf file_size: 9771117 relation: main_file success: 1 file_date_updated: 2025-06-23T10:20:22Z has_accepted_license: '1' intvolume: ' 6' isi: 1 issue: '6' language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: Cell Reports Physical Science publication_identifier: eissn: - 2666-3864 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: STIM1-induced widening of non-pore-lining TM interfaces is crucial for Orai1 pore opening tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 6 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '19847' abstract: - lang: eng text: Prussian blue (PB) and Prussian blue analogues (PBAs) are a class of porous materials composed of transition metal cations, cyanide ligands, and alkali metal cations. Their ability to intercalate and deintercalate ions within their framework pores, coupled with the adaptability of their crystal structure to electrochemical changes, underpins their success in battery applications. PBAs with Fe or Co as the active site exhibit high redox potentials (vs SHE) and have been extensively explored as cathode materials, with well-documented chemistry, crystal structures, and electrochemical properties. In contrast, PBAs with Cr or Mn as the active site display lower redox potentials and remain significantly underexplored as anode materials. This gap has led to fewer reported compounds and a less comprehensive understanding of their structural and electrochemical behavior, leaving the field relatively opaque. In this perspective, we comprehensively analyze the challenges involved in producing and employing PBAs with low redox potentials as active battery materials. Conversely, we propose numerous horizons and ask fundamental questions that should pave the way for future research to advance the field. acknowledgement: All the authors acknowledge financial support by the MeBattery project. MeBattery has received funding from the European Innovation Council of the European Union under Grant Agreement No. 101046742. We acknowledge the valuable scientific discussions with Christine Fiedler. M.P.-C. acknowledges that the project that gave rise to these results received the support of a fellowship from the “la Caixa” Foundation (ID 100010434) with code LCF/BQ/PI24/12040015. E.V. also acknowledges financial support by the Spanish Ministry of Science and Innovation and NextGenerationEU (TED2021-131651B-C21) and Ramón y Cajal award (Ministry of Science and Innovation and European Social Funds, RYC2018-026086-I). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Mario full_name: Palacios Corella, Mario id: 452e82c6-803f-11ed-ab7e-ca0439e73a5d last_name: Palacios Corella - first_name: Igor full_name: Echevarría, Igor id: a623795e-21fb-11ed-b8a1-a0f51308eed7 last_name: Echevarría - first_name: Carla full_name: Santana Santos, Carla last_name: Santana Santos - first_name: Wolfgang full_name: Schuhmann, Wolfgang last_name: Schuhmann - first_name: Edgar full_name: Ventosa, Edgar last_name: Ventosa - first_name: Maria full_name: Ibáñez, Maria id: 43C61214-F248-11E8-B48F-1D18A9856A87 last_name: Ibáñez orcid: 0000-0001-5013-2843 citation: ama: 'Palacios Corella M, Echevarría I, Santana Santos C, Schuhmann W, Ventosa E, Ibáñez M. Prussian blue analogues as anode materials for battery applications: Complexities and horizons. Chemistry of Materials. 2025;37(12):4203-4226. doi:10.1021/acs.chemmater.5c00213' apa: 'Palacios Corella, M., Echevarría, I., Santana Santos, C., Schuhmann, W., Ventosa, E., & Ibáñez, M. (2025). Prussian blue analogues as anode materials for battery applications: Complexities and horizons. Chemistry of Materials. American Chemical Society. https://doi.org/10.1021/acs.chemmater.5c00213' chicago: 'Palacios Corella, Mario, Igor Echevarría, Carla Santana Santos, Wolfgang Schuhmann, Edgar Ventosa, and Maria Ibáñez. “Prussian Blue Analogues as Anode Materials for Battery Applications: Complexities and Horizons.” Chemistry of Materials. American Chemical Society, 2025. https://doi.org/10.1021/acs.chemmater.5c00213.' ieee: 'M. Palacios Corella, I. Echevarría, C. Santana Santos, W. Schuhmann, E. Ventosa, and M. Ibáñez, “Prussian blue analogues as anode materials for battery applications: Complexities and horizons,” Chemistry of Materials, vol. 37, no. 12. American Chemical Society, pp. 4203–4226, 2025.' ista: 'Palacios Corella M, Echevarría I, Santana Santos C, Schuhmann W, Ventosa E, Ibáñez M. 2025. Prussian blue analogues as anode materials for battery applications: Complexities and horizons. Chemistry of Materials. 37(12), 4203–4226.' mla: 'Palacios Corella, Mario, et al. “Prussian Blue Analogues as Anode Materials for Battery Applications: Complexities and Horizons.” Chemistry of Materials, vol. 37, no. 12, American Chemical Society, 2025, pp. 4203–26, doi:10.1021/acs.chemmater.5c00213.' short: M. Palacios Corella, I. Echevarría, C. Santana Santos, W. Schuhmann, E. Ventosa, M. Ibáñez, Chemistry of Materials 37 (2025) 4203–4226. corr_author: '1' date_created: 2025-06-15T22:01:31Z date_published: 2025-06-03T00:00:00Z date_updated: 2025-12-30T08:41:57Z day: '03' ddc: - '540' department: - _id: MaIb doi: 10.1021/acs.chemmater.5c00213 external_id: isi: - '001501830600001' file: - access_level: open_access checksum: 902c52a2f52a028436e0acd8a5a4beac content_type: application/pdf creator: dernst date_created: 2025-12-30T08:40:55Z date_updated: 2025-12-30T08:40:55Z file_id: '20897' file_name: 2025_ChemistryMaterials_PalaciosCorella.pdf file_size: 8760757 relation: main_file success: 1 file_date_updated: 2025-12-30T08:40:55Z has_accepted_license: '1' intvolume: ' 37' isi: 1 issue: '12' language: - iso: eng month: '06' oa: 1 oa_version: Published Version page: 4203-4226 project: - _id: eb9fa02e-77a9-11ec-83b8-ab1143e5a30f grant_number: '101046742' name: MEDIATED BIPHASIC BATTERY publication: Chemistry of Materials publication_identifier: eissn: - 1520-5002 issn: - 0897-4756 publication_status: published publisher: American Chemical Society quality_controlled: '1' scopus_import: '1' status: public title: 'Prussian blue analogues as anode materials for battery applications: Complexities and horizons' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 37 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19848' abstract: - lang: eng text: 'Binding precedents (súmulas vinculantes) constitute a juridical instrument unique to the Brazilian legal system and whose objectives include the protection of the Federal Supreme Court against repetitive demands. Studies of the effectiveness of these instruments in decreasing the Court’s exposure to similar cases, however, indicate that they tend to fail in such a direction, with some of the binding precedents seemingly creating new demands. We empirically assess the legal impact of five binding precedents, 11, 14, 17, 26, and 37, at the highest Court level through their effects on the legal subjects they address. This analysis is only possible through the comparison of the Court’s ruling about the precedents’ themes before they are created, which means that these decisions should be detected through techniques of Similar Case Retrieval, which we tackle from the angle of Case Classification. The contributions of this article are therefore twofold: on the mathematical side, we compare the use of different methods of Natural Language Processing — TF-IDF, LSTM, Longformer, and regex — for Case Classification, whereas on the legal side, we contrast the inefficiency of these binding precedents with a set of hypotheses that may justify their repeated usage. We observe that the TF-IDF models performed slightly better than LSTM and Longformer when compared through common metrics; however, the deep learning models were able to detect certain important legal events that TF-IDF missed. On the legal side, we argue that the reasons for binding precedents to fail in responding to repetitive demand are heterogeneous and case-dependent, making it impossible to single out a specific cause. We identify five main hypotheses, which are found in different combinations in each of the precedents studied.' acknowledgement: Open access funding provided by Institute of Science and Technology (IST Austria). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Raphaël full_name: Tinarrage, Raphaël id: 40ebcc9d-905f-11ef-bf0a-dc475da8a04e last_name: Tinarrage orcid: 0000-0002-1404-1095 - first_name: Henrique full_name: Ennes, Henrique last_name: Ennes - first_name: Lucas full_name: Resck, Lucas last_name: Resck - first_name: Lucas T. full_name: Gomes, Lucas T. last_name: Gomes - first_name: Jean R. full_name: Ponciano, Jean R. last_name: Ponciano - first_name: Jorge full_name: Poco, Jorge last_name: Poco citation: ama: Tinarrage R, Ennes H, Resck L, Gomes LT, Ponciano JR, Poco J. Empirical analysis of binding precedent efficiency in Brazilian Supreme Court via case classification. Artificial Intelligence and Law. 2025. doi:10.1007/s10506-025-09458-6 apa: Tinarrage, R., Ennes, H., Resck, L., Gomes, L. T., Ponciano, J. R., & Poco, J. (2025). Empirical analysis of binding precedent efficiency in Brazilian Supreme Court via case classification. Artificial Intelligence and Law. Springer Nature. https://doi.org/10.1007/s10506-025-09458-6 chicago: Tinarrage, Raphaël, Henrique Ennes, Lucas Resck, Lucas T. Gomes, Jean R. Ponciano, and Jorge Poco. “Empirical Analysis of Binding Precedent Efficiency in Brazilian Supreme Court via Case Classification.” Artificial Intelligence and Law. Springer Nature, 2025. https://doi.org/10.1007/s10506-025-09458-6. ieee: R. Tinarrage, H. Ennes, L. Resck, L. T. Gomes, J. R. Ponciano, and J. Poco, “Empirical analysis of binding precedent efficiency in Brazilian Supreme Court via case classification,” Artificial Intelligence and Law. Springer Nature, 2025. ista: Tinarrage R, Ennes H, Resck L, Gomes LT, Ponciano JR, Poco J. 2025. Empirical analysis of binding precedent efficiency in Brazilian Supreme Court via case classification. Artificial Intelligence and Law. mla: Tinarrage, Raphaël, et al. “Empirical Analysis of Binding Precedent Efficiency in Brazilian Supreme Court via Case Classification.” Artificial Intelligence and Law, Springer Nature, 2025, doi:10.1007/s10506-025-09458-6. short: R. Tinarrage, H. Ennes, L. Resck, L.T. Gomes, J.R. Ponciano, J. Poco, Artificial Intelligence and Law (2025). corr_author: '1' date_created: 2025-06-15T22:01:31Z date_published: 2025-05-26T00:00:00Z date_updated: 2025-09-30T12:52:15Z day: '26' department: - _id: UlWa doi: 10.1007/s10506-025-09458-6 external_id: arxiv: - '2407.07004' isi: - '001494836700001' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/s10506-025-09458-6 month: '05' oa: 1 oa_version: Published Version publication: Artificial Intelligence and Law publication_identifier: eissn: - 1572-8382 issn: - 0924-8463 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Empirical analysis of binding precedent efficiency in Brazilian Supreme Court via case classification type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19852' abstract: - lang: eng text: "Technology involving hybrid superconductor–semiconductor materials is a promising avenue for engineering quantum devices for information storage, manipulation, and transmission. Proximity-induced superconducting correlations are an essential part of such devices. While the proximity effect in the conduction band of common semiconductors is well understood, its manifestation in confined hole gases, realized for instance in germanium, is an active area of research. Lower-dimensional hole-based systems, particularly in germanium, are emerging as an attractive platform for a variety of solid-state quantum devices, due to their combination of efficient spin and charge control and long coherence times. The recent experimental realization of the proximity effect in germanium thus calls for a theoretical description that is tailored to hole gases. In this work, we propose a simple model to describe proximity-induced superconductivity in two-dimensional hole gases, incorporating both the heavy-hole (HH) and light-hole (LH) bands. We start from the Luttinger–Kohn model, introduce three parameters that characterize hopping across the superconductor–semiconductor interface, and derive explicit intraband and interband effective pairing terms for the HH and LH bands. Unlike previous approaches, our theory provides a quantitative relationship between induced pairings and interface properties. Restricting our general model to an experimentally relevant case where only the HH band crosses the chemical potential, we predict the coexistence of \U0001D460-wave and \U0001D451-wave singlet pairings, along with triplet-type pairings, and modified Zeeman and Rashba spin–orbit couplings. Our results thus present a starting point for theoretical modeling of quantum devices based on proximitized hole gases, fueling further progress in quantum technology." acknowledgement: We acknowledge useful discussions with Georgios Katsaros, Andrew Higginbotham, and Oliver Schwarze. This research was funded in part by the Austrian Science Fund (FWF) F 86, the European Research Council (Grant Agreement No. 856526), and by the DFG Collaborative Research Center (CRC) 183 Project No. 277101999. article_number: '214518' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Serafim full_name: Babkin, Serafim id: e63d75c3-72ef-11ef-b75a-e303e149911f last_name: Babkin - first_name: Benjamin full_name: Joecker, Benjamin last_name: Joecker - first_name: Karsten full_name: Flensberg, Karsten last_name: Flensberg - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 - first_name: Jeroen full_name: Danon, Jeroen last_name: Danon citation: ama: Babkin S, Joecker B, Flensberg K, Serbyn M, Danon J. Superconducting proximity effect in two-dimensional hole gases. Physical Review B. 2025;111(21). doi:10.1103/k4jh-pnxy apa: Babkin, S., Joecker, B., Flensberg, K., Serbyn, M., & Danon, J. (2025). Superconducting proximity effect in two-dimensional hole gases. Physical Review B. American Physical Society. https://doi.org/10.1103/k4jh-pnxy chicago: Babkin, Serafim, Benjamin Joecker, Karsten Flensberg, Maksym Serbyn, and Jeroen Danon. “Superconducting Proximity Effect in Two-Dimensional Hole Gases.” Physical Review B. American Physical Society, 2025. https://doi.org/10.1103/k4jh-pnxy. ieee: S. Babkin, B. Joecker, K. Flensberg, M. Serbyn, and J. Danon, “Superconducting proximity effect in two-dimensional hole gases,” Physical Review B, vol. 111, no. 21. American Physical Society, 2025. ista: Babkin S, Joecker B, Flensberg K, Serbyn M, Danon J. 2025. Superconducting proximity effect in two-dimensional hole gases. Physical Review B. 111(21), 214518. mla: Babkin, Serafim, et al. “Superconducting Proximity Effect in Two-Dimensional Hole Gases.” Physical Review B, vol. 111, no. 21, 214518, American Physical Society, 2025, doi:10.1103/k4jh-pnxy. short: S. Babkin, B. Joecker, K. Flensberg, M. Serbyn, J. Danon, Physical Review B 111 (2025). corr_author: '1' date_created: 2025-06-19T16:54:54Z date_published: 2025-06-18T00:00:00Z date_updated: 2025-09-30T12:53:47Z day: '18' ddc: - '530' department: - _id: MaSe - _id: GradSch doi: 10.1103/k4jh-pnxy external_id: arxiv: - '2412.04084' isi: - '001514328000004' file: - access_level: open_access checksum: fa8757f4780cfaeb51579c626284a8c1 content_type: application/pdf creator: dernst date_created: 2025-06-23T10:31:11Z date_updated: 2025-06-23T10:31:11Z file_id: '19869' file_name: 2025_PhysReviewB_Babkin.pdf file_size: 1719489 relation: main_file success: 1 file_date_updated: 2025-06-23T10:31:11Z has_accepted_license: '1' intvolume: ' 111' isi: 1 issue: '21' language: - iso: eng month: '06' oa: 1 oa_version: Published Version project: - _id: 34a7f947-11ca-11ed-8bc3-c5dc2bbaae25 grant_number: F8609 name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems: Probing topology in circuits and quantum materials' publication: Physical Review B publication_identifier: eissn: - 2469-9969 issn: - 2469-9950 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: Superconducting proximity effect in two-dimensional hole gases tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 111 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19854' abstract: - lang: eng text: 'Asynchronous Boolean networks are a type of discrete dynamical system in which each variable can take one of two states, and a single variable state is updated in each time step according to pre-selected rules. Boolean networks are popular in systems biology due to their ability to model long-term biological phenotypes within a qualitative, predictive framework. Boolean networks model phenotypes as attractors, which are closely linked to minimal trap spaces (inescapable hypercubes in the system’s state space). In biological applications, attractors and minimal trap spaces are typically in one-to-one correspondence. However, this correspondence is not guaranteed: motif-avoidant attractors (MAAs) that lie outside minimal trap spaces are possible. MAAs are rare and poorly understood, despite recent efforts. In this contribution to the BMB & JMB Special Collection “Problems, Progress and Perspectives in Mathematical and Computational Biology”, we summarize the current state of knowledge regarding MAAs and present several novel observations regarding their response to node deletion reductions and linear extensions of edges. We conduct large-scale computational studies on an ensemble of 14 000 models derived from published Boolean models of biological systems, and more than 100 million Random Boolean Networks. Our findings quantify the rarity of MAAs; in particular, we only observed MAAs in biological models after applying standard simplification methods, highlighting the role of network reduction in introducing MAAs into the dynamics. We also show that MAAs are fragile to linear extensions: in sparse networks, even a single linear node can disrupt virtually all MAAs. Motivated by this observation, we improve the upper bound on the number of delays needed to disrupt a motif-avoidant attractor.' acknowledgement: Ondřej Huvar has been supported by the Czech Science Foundation grant No. GA22-10845S. Samuel Pastva received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101034413. Kyu Hyong Park and Réka Albert have been supported by NSF grant MCB 1715826 and ARO grant 79961-SM-MUR. No funding bodies had any role in study design, analysis, decision to publish, or preparation of the manuscript. article_number: '11' article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Samuel full_name: Pastva, Samuel id: 07c5ea74-f61c-11ec-a664-aa7c5d957b2b last_name: Pastva orcid: 0000-0003-1993-0331 - first_name: Kyu Hyong full_name: Park, Kyu Hyong last_name: Park - first_name: Ondřej full_name: Huvar, Ondřej last_name: Huvar - first_name: Jordan C. full_name: Rozum, Jordan C. last_name: Rozum - first_name: Réka full_name: Albert, Réka last_name: Albert citation: ama: 'Pastva S, Park KH, Huvar O, Rozum JC, Albert R. An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks? Journal of Mathematical Biology. 2025;91. doi:10.1007/s00285-025-02235-8' apa: 'Pastva, S., Park, K. H., Huvar, O., Rozum, J. C., & Albert, R. (2025). An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks? Journal of Mathematical Biology. Springer Nature. https://doi.org/10.1007/s00285-025-02235-8' chicago: 'Pastva, Samuel, Kyu Hyong Park, Ondřej Huvar, Jordan C. Rozum, and Réka Albert. “An Open Problem: Why Are Motif-Avoidant Attractors so Rare in Asynchronous Boolean Networks?” Journal of Mathematical Biology. Springer Nature, 2025. https://doi.org/10.1007/s00285-025-02235-8.' ieee: 'S. Pastva, K. H. Park, O. Huvar, J. C. Rozum, and R. Albert, “An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks?,” Journal of Mathematical Biology, vol. 91. Springer Nature, 2025.' ista: 'Pastva S, Park KH, Huvar O, Rozum JC, Albert R. 2025. An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks? Journal of Mathematical Biology. 91, 11.' mla: 'Pastva, Samuel, et al. “An Open Problem: Why Are Motif-Avoidant Attractors so Rare in Asynchronous Boolean Networks?” Journal of Mathematical Biology, vol. 91, 11, Springer Nature, 2025, doi:10.1007/s00285-025-02235-8.' short: S. Pastva, K.H. Park, O. Huvar, J.C. Rozum, R. Albert, Journal of Mathematical Biology 91 (2025). corr_author: '1' date_created: 2025-06-22T22:02:05Z date_published: 2025-06-12T00:00:00Z date_updated: 2025-09-30T13:36:46Z day: '12' ddc: - '000' department: - _id: ToHe doi: 10.1007/s00285-025-02235-8 ec_funded: 1 external_id: arxiv: - '2410.03976' isi: - '001507009300001' file: - access_level: open_access checksum: a385ef2662f1d0c3497ed3f2721fe594 content_type: application/pdf creator: dernst date_created: 2025-06-23T11:10:01Z date_updated: 2025-06-23T11:10:01Z file_id: '19871' file_name: 2025_JourMathBiology_Pastva.pdf file_size: 1243163 relation: main_file success: 1 file_date_updated: 2025-06-23T11:10:01Z has_accepted_license: '1' intvolume: ' 91' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Journal of Mathematical Biology publication_identifier: eissn: - 1432-1416 issn: - 0303-6812 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: 'An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks?' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 91 year: '2025' ... --- OA_place: publisher OA_type: gold _id: '19855' abstract: - lang: eng text: We present indirect constraints on the absolute escape fraction of ionizing photons (f_{\rm esc}^{\rm LyC}) of the system GN 42912 which comprises two luminous galaxies (M_{\rm UV} magnitudes of -20.89 and -20.37) at z\sim7.5, GN 42912-NE and GN 42912-SW, to determine their contribution to the ionizing photon budget of the Epoch of Reionization (EoR). The high-resolution James Webb Space Telescope NIRSpec and NIRCam observations reveal the two galaxies are separated by only ~0.1" (0.5 kpc) on the sky and have a 358 km s^{-1} velocity separation. GN 42912-NE and GN 42912-SW are relatively massive for this redshift (log(M_\ast/M_\odot) \sim 8.4 and 8.9, respectively), with gas-phase metallicities of 18 per cent and 23 per cent solar, O_{32} ratios of 5.3 and >5.8, and \beta slopes of -1.92 and -1.51, respectively. We use the Mg II\lambda\lambda2796,2803 doublet to constrain f_{\rm esc}^{\rm LyC}. Mg II has an ionization potential close to that of neutral hydrogen and, in the optically thin regime, can be used as an indirect tracer of the LyC leakage. We establish realistic conservative upper limits on f_{\rm esc}^{\rm LyC} of 8.5 per cent for GN 42912-NE and 14 per cent for GN 42912-SW. These estimates align with f_{\rm esc}^{\rm LyC} trends observed with \beta, O_{32}, and the H\beta equivalent width at z<4. The small inferred ionized region sizes (<0.3 pMpc) around both galaxies indicate they have not ionized a significant fraction of the surrounding neutral gas. While these z>7 f_{\rm esc}^{\rm LyC} constraints do not decisively determine a specific reionization model, they support a minor contribution from these two relatively luminous galaxies to the EoR. acknowledgement: 'This work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5–03127 for JWST. These observations are associated with program #01871. Support for program #01871 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5–03127. SG is grateful for the support enabled by the Harlan J. Smith McDonald fellowship. YI and NG acknowledge support from the Simons Foundation and the National Academy of Sciences of Ukraine (Project 0121U109612). ASL acknowledges support from Knut and Alice Wallenberg Foundation.' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: S. full_name: Gazagnes, S. last_name: Gazagnes - first_name: J. full_name: Chisholm, J. last_name: Chisholm - first_name: R. full_name: Endsley, R. last_name: Endsley - first_name: D. A. full_name: Berg, D. A. last_name: Berg - first_name: F. full_name: Leclercq, F. last_name: Leclercq - first_name: N. full_name: Jurlin, N. last_name: Jurlin - first_name: A. full_name: Saldana-Lopez, A. last_name: Saldana-Lopez - first_name: S. L. full_name: Finkelstein, S. L. last_name: Finkelstein - first_name: S. R. full_name: Flury, S. R. last_name: Flury - first_name: N. G. full_name: Guseva, N. G. last_name: Guseva - first_name: A. full_name: Henry, A. last_name: Henry - first_name: Y. I. full_name: Izotov, Y. I. last_name: Izotov - first_name: I. full_name: Jung, I. last_name: Jung - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: D. full_name: Schaerer, D. last_name: Schaerer citation: ama: Gazagnes S, Chisholm J, Endsley R, et al. A negligible contribution of two luminous z ∼7.5 galaxies to the ionizing photon budget of reionization. Monthly Notices of the Royal Astronomical Society. 2025;540(3):2331-2348. doi:10.1093/mnras/staf768 apa: Gazagnes, S., Chisholm, J., Endsley, R., Berg, D. A., Leclercq, F., Jurlin, N., … Schaerer, D. (2025). A negligible contribution of two luminous z ∼7.5 galaxies to the ionizing photon budget of reionization. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/staf768 chicago: Gazagnes, S., J. Chisholm, R. Endsley, D. A. Berg, F. Leclercq, N. Jurlin, A. Saldana-Lopez, et al. “A Negligible Contribution of Two Luminous z ∼7.5 Galaxies to the Ionizing Photon Budget of Reionization.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2025. https://doi.org/10.1093/mnras/staf768. ieee: S. Gazagnes et al., “A negligible contribution of two luminous z ∼7.5 galaxies to the ionizing photon budget of reionization,” Monthly Notices of the Royal Astronomical Society, vol. 540, no. 3. Oxford University Press, pp. 2331–2348, 2025. ista: Gazagnes S, Chisholm J, Endsley R, Berg DA, Leclercq F, Jurlin N, Saldana-Lopez A, Finkelstein SL, Flury SR, Guseva NG, Henry A, Izotov YI, Jung I, Matthee JJ, Schaerer D. 2025. A negligible contribution of two luminous z ∼7.5 galaxies to the ionizing photon budget of reionization. Monthly Notices of the Royal Astronomical Society. 540(3), 2331–2348. mla: Gazagnes, S., et al. “A Negligible Contribution of Two Luminous z ∼7.5 Galaxies to the Ionizing Photon Budget of Reionization.” Monthly Notices of the Royal Astronomical Society, vol. 540, no. 3, Oxford University Press, 2025, pp. 2331–48, doi:10.1093/mnras/staf768. short: S. Gazagnes, J. Chisholm, R. Endsley, D.A. Berg, F. Leclercq, N. Jurlin, A. Saldana-Lopez, S.L. Finkelstein, S.R. Flury, N.G. Guseva, A. Henry, Y.I. Izotov, I. Jung, J.J. Matthee, D. Schaerer, Monthly Notices of the Royal Astronomical Society 540 (2025) 2331–2348. date_created: 2025-06-22T22:02:05Z date_published: 2025-07-01T00:00:00Z date_updated: 2025-09-30T13:34:20Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1093/mnras/staf768 external_id: arxiv: - '2410.03337' isi: - '001506103600001' file: - access_level: open_access checksum: f912c990a0474f1ddf9be6b8a89c7759 content_type: application/pdf creator: dernst date_created: 2025-06-23T11:02:59Z date_updated: 2025-06-23T11:02:59Z file_id: '19870' file_name: 2025_MonthlyNoticesRAS_Gazagnes.pdf file_size: 3111567 relation: main_file success: 1 file_date_updated: 2025-06-23T11:02:59Z has_accepted_license: '1' intvolume: ' 540' isi: 1 issue: '3' language: - iso: eng month: '07' oa: 1 oa_version: Published Version page: 2331-2348 publication: Monthly Notices of the Royal Astronomical Society publication_identifier: eissn: - 1365-2966 issn: - 0035-8711 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: A negligible contribution of two luminous z ∼7.5 galaxies to the ionizing photon budget of reionization tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 540 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19857' abstract: - lang: eng text: Bacteria have evolved a wide range of defence strategies to protect themselves against bacterial viruses (phages). Most known bacterial antiphage defence systems target phages with DNA genomes, which raises the question of how bacteria defend against phages with RNA genomes. Bacterial toxin–antitoxin systems that cleave intracellular RNA could potentially protect bacteria against RNA phages, but this has not been explored experimentally. In this study, we investigated the role of a model toxin–antitoxin system, MazEF, in protecting Escherichia coli against two RNA phage species. When challenged with these phages, the native presence of mazEF moderately reduced population susceptibility and increased the survival of individual E. coli cells. Genomic analysis further revealed an underrepresentation of the MazF cleavage site in genomes of RNA phages infecting E. coli, indicating selection against cleavage. These results show that, in addition to other physiological roles, RNA-degrading toxin–antitoxin systems may also help defend against RNA phages. acknowledged_ssus: - _id: LifeSc acknowledgement: This work was supported by ISTFELLOW (People Program – Marie Curie Actions of the European Union’s Seventh Framework Program FP7 under REA grant agreement 291734), the FWF (Austrian Science Fund) Elise Richter Program project number V 738 and the Wellcome Trust Institutional Strategic Support Award (WT105618MA), to N.N. M.P. was a Simons Foundation Fellow of the Life Sciences Research Foundation. We are grateful to Kathrin Tomasek, Lisa Butt, Chris Estell, Alys Jepson, Franklin Nobrega, Stefano Pagliara, Remy Chait, Steve West, Vicki Gold, Josh Eaton, Ivana Gudelj and Rob Beardmore for useful discussions and technical support, as well as to Robin Wright, Christian Fitch and Ben Temperton for sharing equipment. We thank Laurence Van Melderen for sharing the strains. We acknowledge the IST Austria Lab Support Facility, LSI Technical Services Team at the University of Exeter and the Translational Research Exchange @ Exeter (TREE) network. N.N. is grateful to Fabrice Gielen for his support. article_number: '20250080' article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Nela full_name: Nikolic, Nela id: 42D9CABC-F248-11E8-B48F-1D18A9856A87 last_name: Nikolic orcid: 0000-0001-9068-6090 - first_name: Maros full_name: Pleska, Maros id: 4569785E-F248-11E8-B48F-1D18A9856A87 last_name: Pleska orcid: 0000-0001-7460-7479 - first_name: Tobias full_name: Bergmiller, Tobias id: 2C471CFA-F248-11E8-B48F-1D18A9856A87 last_name: Bergmiller orcid: 0000-0001-5396-4346 - first_name: Calin C full_name: Guet, Calin C id: 47F8433E-F248-11E8-B48F-1D18A9856A87 last_name: Guet orcid: 0000-0001-6220-2052 citation: ama: Nikolic N, Pleska M, Bergmiller T, Guet CC. A bacterial toxin-antitoxin system as a native defence element against RNA phages. Biology Letters. 2025;21(6). doi:10.1098/rsbl.2025.0080 apa: Nikolic, N., Pleska, M., Bergmiller, T., & Guet, C. C. (2025). A bacterial toxin-antitoxin system as a native defence element against RNA phages. Biology Letters. The Royal Society. https://doi.org/10.1098/rsbl.2025.0080 chicago: Nikolic, Nela, Maros Pleska, Tobias Bergmiller, and Calin C Guet. “A Bacterial Toxin-Antitoxin System as a Native Defence Element against RNA Phages.” Biology Letters. The Royal Society, 2025. https://doi.org/10.1098/rsbl.2025.0080. ieee: N. Nikolic, M. Pleska, T. Bergmiller, and C. C. Guet, “A bacterial toxin-antitoxin system as a native defence element against RNA phages,” Biology Letters, vol. 21, no. 6. The Royal Society, 2025. ista: Nikolic N, Pleska M, Bergmiller T, Guet CC. 2025. A bacterial toxin-antitoxin system as a native defence element against RNA phages. Biology Letters. 21(6), 20250080. mla: Nikolic, Nela, et al. “A Bacterial Toxin-Antitoxin System as a Native Defence Element against RNA Phages.” Biology Letters, vol. 21, no. 6, 20250080, The Royal Society, 2025, doi:10.1098/rsbl.2025.0080. short: N. Nikolic, M. Pleska, T. Bergmiller, C.C. Guet, Biology Letters 21 (2025). corr_author: '1' date_created: 2025-06-22T22:02:06Z date_published: 2025-06-11T00:00:00Z date_updated: 2025-09-30T13:38:08Z day: '11' ddc: - '570' department: - _id: CaGu doi: 10.1098/rsbl.2025.0080 ec_funded: 1 external_id: isi: - '001505019800001' pmid: - '40494395' file: - access_level: open_access checksum: 016f644ed068f8609ded306ad26dbd3f content_type: application/pdf creator: dernst date_created: 2025-06-23T11:34:39Z date_updated: 2025-06-23T11:34:39Z file_id: '19873' file_name: 2025_BiologyLetters_Nikolic.pdf file_size: 1850797 relation: main_file success: 1 file_date_updated: 2025-06-23T11:34:39Z has_accepted_license: '1' intvolume: ' 21' isi: 1 issue: '6' language: - iso: eng month: '06' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 25681D80-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '291734' name: International IST Postdoc Fellowship Programme - _id: 26956E74-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: V00738 name: Bacterial toxin-antitoxin systems as antiphage defense mechanisms publication: Biology Letters publication_identifier: eissn: - 1744-957X issn: - 1744-9561 publication_status: published publisher: The Royal Society quality_controlled: '1' scopus_import: '1' status: public title: A bacterial toxin-antitoxin system as a native defence element against RNA phages tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 21 year: '2025' ... --- OA_place: publisher OA_type: gold _id: '19858' abstract: - lang: eng text: "Given a graph G that undergoes a sequence of edge insertions and deletions, we study the Maximum k-Edge Coloring problem (MkEC): Having access to k different colors, color as many edges of G as possible such that no two adjacent edges share the same color. While this problem is different from simply maintaining a b-matching with b = k, the two problems are related. However, maximum b-matching can be solved efficiently in the static setting, whereas MkEC is NP-hard and even APX-hard for k ≥ 2. \r\nWe present new results on both problems: For b-matching, we show a new integrality gap result and we adapt Wajc’s matching sparsification scheme [David Wajc, 2020] for the case where b is a constant.\r\nUsing these as basis, we give three new algorithms for the dynamic MkEC problem: Our MatchO algorithm builds on the dynamic (2+ε)-approximation algorithm of Bhattacharya, Gupta, and Mohan [Sayan Bhattacharya et al., 2017] for b-matching and achieves a (2+ε)(k+1)/k-approximation in O(poly(log n, ε^-1)) update time against an oblivious adversary. Our MatchA algorithm builds on the dynamic (7+ε)-approximation algorithm by Bhattacharya, Henzinger, and Italiano [Sayan Bhattacharya et al., 2015] for fractional b-matching and achieves a (7+ε)(3k+3)/(3k-1)-approximation in O(poly(log n, ε^-1)) update time against an adaptive adversary. Moreover, our reductions use the dynamic b-matching algorithm as a black box, so any future improvement in the approximation ratio for dynamic b-matching will automatically translate into a better approximation ratio for our algorithms. Finally, we present a greedy algorithm with O(Δ+k) update time, which guarantees a 2.16 approximation factor." acknowledgement: "This project has received funding from the European Research Council (ERC) under the\r\nEuropean Union’s Horizon 2020 research and innovation programme (MoDynStruct, No. 101019564) and the Austrian Science Fund (FWF) grant DOI 10.55776/Z422, grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775 with additional funding from the netidee SCIENCE Stiftung, 2020–2024. This work was further supported by the Federal Ministry of Education and Research (BMBF) project, 6G-RIC: 6G Research and Innovation Cluster, grant 16KISK020K." alternative_title: - LIPIcs article_number: '4' article_processing_charge: No arxiv: 1 author: - first_name: Antoine full_name: El-Hayek, Antoine id: 888a098e-fcac-11ee-aff7-d347be57b725 last_name: El-Hayek orcid: 0000-0003-4268-7368 - first_name: Kathrin full_name: Hanauer, Kathrin last_name: Hanauer - first_name: Monika H full_name: Henzinger, Monika H id: 540c9bbd-f2de-11ec-812d-d04a5be85630 last_name: Henzinger orcid: 0000-0002-5008-6530 citation: ama: 'El-Hayek A, Hanauer K, Henzinger M. On b-matching and fully-dynamic maximum k-edge coloring. In: 4th Symposium on Algorithmic Foundations of Dynamic Networks. Vol 330. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2025. doi:10.4230/LIPIcs.SAND.2025.4' apa: 'El-Hayek, A., Hanauer, K., & Henzinger, M. (2025). On b-matching and fully-dynamic maximum k-edge coloring. In 4th Symposium on Algorithmic Foundations of Dynamic Networks (Vol. 330). Liverpool, United Kingdom: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SAND.2025.4' chicago: El-Hayek, Antoine, Kathrin Hanauer, and Monika Henzinger. “On B-Matching and Fully-Dynamic Maximum k-Edge Coloring.” In 4th Symposium on Algorithmic Foundations of Dynamic Networks, Vol. 330. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025. https://doi.org/10.4230/LIPIcs.SAND.2025.4. ieee: A. El-Hayek, K. Hanauer, and M. Henzinger, “On b-matching and fully-dynamic maximum k-edge coloring,” in 4th Symposium on Algorithmic Foundations of Dynamic Networks, Liverpool, United Kingdom, 2025, vol. 330. ista: 'El-Hayek A, Hanauer K, Henzinger M. 2025. On b-matching and fully-dynamic maximum k-edge coloring. 4th Symposium on Algorithmic Foundations of Dynamic Networks. SAND: Symposium on Algorithmic Foundations of Dynamic Networks, LIPIcs, vol. 330, 4.' mla: El-Hayek, Antoine, et al. “On B-Matching and Fully-Dynamic Maximum k-Edge Coloring.” 4th Symposium on Algorithmic Foundations of Dynamic Networks, vol. 330, 4, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025, doi:10.4230/LIPIcs.SAND.2025.4. short: A. El-Hayek, K. Hanauer, M. Henzinger, in:, 4th Symposium on Algorithmic Foundations of Dynamic Networks, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2025. conference: end_date: 2025-06-11 location: Liverpool, United Kingdom name: 'SAND: Symposium on Algorithmic Foundations of Dynamic Networks' start_date: 2025-06-09 corr_author: '1' date_created: 2025-06-22T22:02:06Z date_published: 2025-06-02T00:00:00Z date_updated: 2025-09-30T13:37:28Z day: '02' ddc: - '000' department: - _id: MoHe doi: 10.4230/LIPIcs.SAND.2025.4 ec_funded: 1 external_id: arxiv: - '2310.01149' isi: - '001532136900004' file: - access_level: open_access checksum: ad93a1e052adb29d7bfe8bd551bab193 content_type: application/pdf creator: dernst date_created: 2025-06-23T11:23:29Z date_updated: 2025-06-23T11:23:29Z file_id: '19872' file_name: 2025_LIPIcs_ElHayek.pdf file_size: 995666 relation: main_file success: 1 file_date_updated: 2025-06-23T11:23:29Z has_accepted_license: '1' intvolume: ' 330' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version project: - _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62 call_identifier: H2020 grant_number: '101019564' name: The design and evaluation of modern fully dynamic data structures - _id: 34def286-11ca-11ed-8bc3-da5948e1613c grant_number: Z00422 name: Efficient algorithms - _id: bda196b2-d553-11ed-ba76-8e8ee6c21103 grant_number: I05982 name: Static and Dynamic Hierarchical Graph Decompositions - _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe grant_number: P33775 name: Fast Algorithms for a Reactive Network Layer publication: 4th Symposium on Algorithmic Foundations of Dynamic Networks publication_identifier: isbn: - '9783959773683' issn: - 1868-8969 publication_status: published publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik quality_controlled: '1' scopus_import: '1' status: public title: On b-matching and fully-dynamic maximum k-edge coloring tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 330 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '19859' abstract: - lang: eng text: "We consider a recently introduced model of color-avoiding percolation (abbreviated CA-percolation) defined as follows. Every edge in a graph G is colored in some of k>=2 colors. Two vertices u and v in G are said to be CA-connected if u and v may be connected using any subset of k-1 colors. CA-connectivity defines an equivalence relation on the vertex set of G whose classes are called CA-components.\r\nWe study the component structure of a randomly colored Erdős–Rényi random graph of constant average degree. We distinguish three regimes for the size of the largest component: a supercritical regime, a so-called intermediate regime, and a subcritical regime, in which the largest CA-component has respectively linear, logarithmic, and bounded size. Interestingly, in the subcritical regime, the bound is deterministic and given by the number of colors." acknowledgement: "We thank Dieter Mitsche for enlightening discussions, Balázs Ráth for a number of comments\r\nand corrections on a first version of this paper, and an anonymous referee for several useful remarks." article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: Lyuben full_name: Lichev, Lyuben id: 9aa8388e-d003-11ee-8458-c4c1d7447977 last_name: Lichev - first_name: Bruno full_name: Schapira, Bruno last_name: Schapira citation: ama: Lichev L, Schapira B. Color-avoiding percolation on the Erdős–Rényi random graph. Annales Henri Lebesgue. 2025;8:35-65. doi:10.5802/ahl.228 apa: Lichev, L., & Schapira, B. (2025). Color-avoiding percolation on the Erdős–Rényi random graph. Annales Henri Lebesgue. École normale supérieure de Rennes. https://doi.org/10.5802/ahl.228 chicago: Lichev, Lyuben, and Bruno Schapira. “Color-Avoiding Percolation on the Erdős–Rényi Random Graph.” Annales Henri Lebesgue. École normale supérieure de Rennes, 2025. https://doi.org/10.5802/ahl.228. ieee: L. Lichev and B. Schapira, “Color-avoiding percolation on the Erdős–Rényi random graph,” Annales Henri Lebesgue, vol. 8. École normale supérieure de Rennes, pp. 35–65, 2025. ista: Lichev L, Schapira B. 2025. Color-avoiding percolation on the Erdős–Rényi random graph. Annales Henri Lebesgue. 8, 35–65. mla: Lichev, Lyuben, and Bruno Schapira. “Color-Avoiding Percolation on the Erdős–Rényi Random Graph.” Annales Henri Lebesgue, vol. 8, École normale supérieure de Rennes, 2025, pp. 35–65, doi:10.5802/ahl.228. short: L. Lichev, B. Schapira, Annales Henri Lebesgue 8 (2025) 35–65. corr_author: '1' date_created: 2025-06-22T22:02:07Z date_published: 2025-06-01T00:00:00Z date_updated: 2025-06-23T12:01:36Z day: '01' ddc: - '510' department: - _id: MaKw doi: 10.5802/ahl.228 external_id: arxiv: - '2211.16086 ' file: - access_level: open_access checksum: cca22d171b7affa010d17f5e793b0045 content_type: application/pdf creator: dernst date_created: 2025-06-23T11:59:22Z date_updated: 2025-06-23T11:59:22Z file_id: '19875' file_name: 2025_AnnalesHenriLebesgue_Lichev.pdf file_size: 746588 relation: main_file success: 1 file_date_updated: 2025-06-23T11:59:22Z has_accepted_license: '1' intvolume: ' 8' language: - iso: eng month: '06' oa: 1 oa_version: Published Version page: 35-65 publication: Annales Henri Lebesgue publication_identifier: eissn: - 2644-9463 publication_status: published publisher: École normale supérieure de Rennes quality_controlled: '1' scopus_import: '1' status: public title: Color-avoiding percolation on the Erdős–Rényi random graph tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 8 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19876' abstract: - lang: eng text: "Assortative mating and sexual selection are widespread in nature and can play an important role in speciation by facilitating the buildup and maintenance of reproductive isolation (RI). However, their contribution to genome-wide suppression of gene flow during RI is rarely quantified.\r\nHere, we consider a polygenic “magic” trait that is divergently selected across two populations connected by migration, while also serving as the basis of assortative mating, thus generating sexual selection on one or both sexes. We obtain theoretical predictions for divergence at\r\nindividual trait loci by assuming that the effect of all other loci on any locus can be encapsulated via an effective migration rate, which bears a simple relationship to measurable fitness components of migrants and various early-generation hybrids. Our analysis clarifies how “tipping\r\npoints” (characterized by an abrupt collapse of adaptive divergence) arise, and when assortative mating can shift the critical level of migration beyond which divergence collapses. We quantify the relative contributions of viability and sexual selection to genome-wide barriers to gene\r\nflow and discuss how these depend on existing divergence levels. Our results suggest that effective migration rates provide a useful way of understanding genomic divergence, even in scenarios involving multiple, interacting mechanisms of RI. " acknowledged_ssus: - _id: ScienComp acknowledgement: We thank Nick Barton for useful comments on the manuscript. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by Scientific Computing (SciComp). article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Parvathy full_name: Surendranadh, Parvathy id: 455235B8-F248-11E8-B48F-1D18A9856A87 last_name: Surendranadh orcid: 0000-0001-6395-386X - first_name: Himani full_name: Sachdeva, Himani last_name: Sachdeva citation: ama: Surendranadh P, Sachdeva H. Effect of assortative mating and sexual selection on polygenic barriers to gene flow. Evolution. 2025;79(7):1185-1198. doi:10.1093/evolut/qpaf047 apa: Surendranadh, P., & Sachdeva, H. (2025). Effect of assortative mating and sexual selection on polygenic barriers to gene flow. Evolution. Oxford University Press. https://doi.org/10.1093/evolut/qpaf047 chicago: Surendranadh, Parvathy, and Himani Sachdeva. “Effect of Assortative Mating and Sexual Selection on Polygenic Barriers to Gene Flow.” Evolution. Oxford University Press, 2025. https://doi.org/10.1093/evolut/qpaf047. ieee: P. Surendranadh and H. Sachdeva, “Effect of assortative mating and sexual selection on polygenic barriers to gene flow,” Evolution, vol. 79, no. 7. Oxford University Press, pp. 1185–1198, 2025. ista: Surendranadh P, Sachdeva H. 2025. Effect of assortative mating and sexual selection on polygenic barriers to gene flow. Evolution. 79(7), 1185–1198. mla: Surendranadh, Parvathy, and Himani Sachdeva. “Effect of Assortative Mating and Sexual Selection on Polygenic Barriers to Gene Flow.” Evolution, vol. 79, no. 7, Oxford University Press, 2025, pp. 1185–98, doi:10.1093/evolut/qpaf047. short: P. Surendranadh, H. Sachdeva, Evolution 79 (2025) 1185–1198. corr_author: '1' date_created: 2025-06-23T13:51:00Z date_published: 2025-07-01T00:00:00Z date_updated: 2025-12-30T08:44:13Z day: '01' ddc: - '570' department: - _id: NiBa doi: 10.1093/evolut/qpaf047 external_id: isi: - '001490646300001' file: - access_level: open_access checksum: 288ca936cef794d68a55356e70671846 content_type: application/pdf creator: dernst date_created: 2025-12-30T08:43:33Z date_updated: 2025-12-30T08:43:33Z file_id: '20898' file_name: 2025_Evolution_Surendranadh.pdf file_size: 2784295 relation: main_file success: 1 file_date_updated: 2025-12-30T08:43:33Z has_accepted_license: '1' intvolume: ' 79' isi: 1 issue: '7' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '07' oa: 1 oa_version: Published Version page: 1185-1198 publication: Evolution publication_identifier: eissn: - 1558-5646 issn: - 0014-3820 publication_status: published publisher: Oxford University Press quality_controlled: '1' related_material: record: - id: '18712' relation: research_data status: public scopus_import: '1' status: public title: Effect of assortative mating and sexual selection on polygenic barriers to gene flow tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 79 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19877' abstract: - lang: eng text: "As inference on Large Language Models (LLMs) emerges as an important workload in machine learning applications, model weight quantization has become a standard technique for efficient GPU deployment. Quantization not only reduces model size, but has also been shown to yield substantial speedups for single-user inference, due to reduced memory movement, with low accuracy impact. Yet, it remains a key open question whether speedups are achievable also in batched settings with multiple parallel clients, which are highly relevant for practical serving. It is unclear whether GPU kernels can be designed to remain practically memory-bound, while supporting the substantially increased compute requirements of batched workloads.\r\nIn this paper, we resolve this question positively by introducing a new design for Mixed-precision Auto-Regressive LINear kernels, called MARLIN. Concretely, given a model whose weights are compressed via quantization to, e.g., 4 bits per element, MARLIN shows that batchsizes up to 16-32 can be practically supported with close to maximum (4×) quantization speedup, and larger batchsizes up to 64-128 with gradually decreasing, but still significant, acceleration. MARLIN accomplishes this via a combination of techniques, such as asynchronous memory access, complex task scheduling and pipelining, and bespoke quantization support. Our experiments show that MARLIN's near-optimal performance on individual LLM layers across different scenarios can also lead to significant end-to-end LLM inference speedups (of up to 2.8×) when integrated with the popular vLLM open-source serving engine. Finally, we show that MARLIN is extensible to further compression techniques, like NVIDIA 2:4 sparsity, leading to additional speedups." acknowledgement: The authors would like to thank the Neural Magic team, in particular Michael Goin, Alexander Matveev, and Rob Shaw, for support with the vLLM integration. This research was supported in part by generous grants from NVIDIA and Google. article_processing_charge: Yes (via OA deal) arxiv: 1 author: - first_name: Elias full_name: Frantar, Elias id: 09a8f98d-ec99-11ea-ae11-c063a7b7fe5f last_name: Frantar - first_name: Roberto L. full_name: Castro, Roberto L. last_name: Castro - first_name: Jiale full_name: Chen, Jiale id: 4d0a9064-1ff6-11ee-9fa6-ec046c604785 last_name: Chen orcid: 0000-0001-5337-5875 - first_name: Torsten full_name: Hoefler, Torsten last_name: Hoefler - first_name: Dan-Adrian full_name: Alistarh, Dan-Adrian id: 4A899BFC-F248-11E8-B48F-1D18A9856A87 last_name: Alistarh orcid: 0000-0003-3650-940X citation: ama: 'Frantar E, Castro RL, Chen J, Hoefler T, Alistarh D-A. MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models. In: Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming. Association for Computing Machinery; 2025:239-251. doi:10.1145/3710848.3710871' apa: 'Frantar, E., Castro, R. L., Chen, J., Hoefler, T., & Alistarh, D.-A. (2025). MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models. In Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming (pp. 239–251). Las Vegas, NV, United States: Association for Computing Machinery. https://doi.org/10.1145/3710848.3710871' chicago: 'Frantar, Elias, Roberto L. Castro, Jiale Chen, Torsten Hoefler, and Dan-Adrian Alistarh. “MARLIN: Mixed-Precision Auto-Regressive Parallel Inference on Large Language Models.” In Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming, 239–51. Association for Computing Machinery, 2025. https://doi.org/10.1145/3710848.3710871.' ieee: 'E. Frantar, R. L. Castro, J. Chen, T. Hoefler, and D.-A. Alistarh, “MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models,” in Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming, Las Vegas, NV, United States, 2025, pp. 239–251.' ista: 'Frantar E, Castro RL, Chen J, Hoefler T, Alistarh D-A. 2025. MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models. Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming. PPoPP: Symposium on Principles and Practice of Parallel Programming, 239–251.' mla: 'Frantar, Elias, et al. “MARLIN: Mixed-Precision Auto-Regressive Parallel Inference on Large Language Models.” Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming, Association for Computing Machinery, 2025, pp. 239–51, doi:10.1145/3710848.3710871.' short: E. Frantar, R.L. Castro, J. Chen, T. Hoefler, D.-A. Alistarh, in:, Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming, Association for Computing Machinery, 2025, pp. 239–251. conference: end_date: 2025-03-05 location: Las Vegas, NV, United States name: 'PPoPP: Symposium on Principles and Practice of Parallel Programming' start_date: 2025-03-01 corr_author: '1' date_created: 2025-06-23T13:51:58Z date_published: 2025-02-28T00:00:00Z date_updated: 2025-09-30T13:41:57Z day: '28' ddc: - '000' department: - _id: DaAl doi: 10.1145/3710848.3710871 external_id: arxiv: - '2408.11743' isi: - '001437826500019' file: - access_level: open_access checksum: a0566ea3c168e8273501a5eb7d767cf8 content_type: application/pdf creator: dernst date_created: 2025-06-24T06:04:17Z date_updated: 2025-06-24T06:04:17Z file_id: '19883' file_name: 2025_PPoPP_Frantar.pdf file_size: 1330044 relation: main_file success: 1 file_date_updated: 2025-06-24T06:04:17Z has_accepted_license: '1' isi: 1 language: - iso: eng month: '02' oa: 1 oa_version: Published Version page: 239-251 publication: Proceedings of the 30th ACM SIGPLAN Annual Symposium on Principles and Practice of Parallel Programming publication_identifier: isbn: - '9798400714436' publication_status: published publisher: Association for Computing Machinery quality_controlled: '1' related_material: record: - id: '19884' relation: software status: public scopus_import: '1' status: public title: 'MARLIN: Mixed-precision auto-regressive parallel inference on Large Language Models' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19878' abstract: - lang: eng text: Rock debris partially covers glaciers worldwide, with varying extents and distributions, and controls sub‐debris melt rates by modifying energy transfer from the atmosphere to the ice. Two key physical properties controlling this energy exchange are thermal conductivity (k) and aerodynamic roughness length (z0). Accurate representation of these properties in energy‐balance models is critical for understanding climate‐glacier interactions and predicting the behavior of debris‐covered glaciers. However, k and z0 have been derived at very few sites from limited local measurements, using different approaches, and most model applications rely on values reported from these few sites and studies. We derive k and z0 using established and modified approaches from data at three locations on Pirámide Glacier in the central Chilean Andes. By comparing methods and evaluating melt simulated with an energy‐balance model, we reveal substantial differences between approaches. These lead to discrepancies between ice melt from energy‐balance simulations and observed data, and highlight the impact of method choice on calculated ice melt. Optimizing k against measured melt appears a viable approach to constrain melt simulations. Determining z0 seems less critical, as it has a smaller impact on total melt. Profile aerodynamic method measurements for estimating z0, despite higher costs, are independent of ice melt calculations. The large, unexpected differences between methods indicate a substantial knowledge gap. The fact that field‐derived k and z0 fail to work well in energy‐balance models, suggests that model values represent bulk properties distinct from theoretical field measurements. Addressing this gap is essential for improving glacier melt predictions. acknowledgement: This project received funding from the Swiss National Science Foundation (Grant 204322, project “REsolving the thickNess Of debris on Earth's glacIers and its Rate of change,” RENOIR). We thank Lars Groeneveld, Diego Hernández, Alonso Mejías, Gabriela Reyes and Gabriela Tala for their support during fieldwork. Open access funding provided by Institute of Science and Technology Austria/KEMÖ. article_number: e2025JF008360 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Juan Vicente full_name: Melo Velasco, Juan Vicente id: 2611dec0-b9c6-11ed-9bea-a81c2b17a549 last_name: Melo Velasco - first_name: Evan full_name: Miles, Evan last_name: Miles - first_name: Michael full_name: McCarthy, Michael id: 22a2674a-61ce-11ee-94b5-d18813baf16f last_name: McCarthy - first_name: Thomas full_name: Shaw, Thomas id: 3caa3f91-1f03-11ee-96ce-e0e553054d6e last_name: Shaw orcid: 0000-0001-7640-6152 - first_name: Catriona Louise full_name: Fyffe, Catriona Louise id: 001b0422-8d15-11ed-bc51-cab6c037a228 last_name: Fyffe - first_name: Adrià full_name: Fontrodona-Bach, Adrià id: f06891fd-9f42-11ee-8632-a20971c43046 last_name: Fontrodona-Bach - first_name: Francesca full_name: Pellicciotti, Francesca id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70 last_name: Pellicciotti orcid: 0000-0002-5554-8087 citation: ama: 'Melo Velasco JV, Miles E, McCarthy M, et al. Method dependence in thermal conductivity and aerodynamic roughness length estimates on a debris‐covered glacier. Journal of Geophysical Research: Earth Surface. 2025;130(6). doi:10.1029/2025jf008360' apa: 'Melo Velasco, J. V., Miles, E., McCarthy, M., Shaw, T., Fyffe, C. L., Fontrodona-Bach, A., & Pellicciotti, F. (2025). Method dependence in thermal conductivity and aerodynamic roughness length estimates on a debris‐covered glacier. Journal of Geophysical Research: Earth Surface. Wiley. https://doi.org/10.1029/2025jf008360' chicago: 'Melo Velasco, Juan Vicente, Evan Miles, Michael McCarthy, Thomas Shaw, Catriona Louise Fyffe, Adrià Fontrodona-Bach, and Francesca Pellicciotti. “Method Dependence in Thermal Conductivity and Aerodynamic Roughness Length Estimates on a Debris‐covered Glacier.” Journal of Geophysical Research: Earth Surface. Wiley, 2025. https://doi.org/10.1029/2025jf008360.' ieee: 'J. V. Melo Velasco et al., “Method dependence in thermal conductivity and aerodynamic roughness length estimates on a debris‐covered glacier,” Journal of Geophysical Research: Earth Surface, vol. 130, no. 6. Wiley, 2025.' ista: 'Melo Velasco JV, Miles E, McCarthy M, Shaw T, Fyffe CL, Fontrodona-Bach A, Pellicciotti F. 2025. Method dependence in thermal conductivity and aerodynamic roughness length estimates on a debris‐covered glacier. Journal of Geophysical Research: Earth Surface. 130(6), e2025JF008360.' mla: 'Melo Velasco, Juan Vicente, et al. “Method Dependence in Thermal Conductivity and Aerodynamic Roughness Length Estimates on a Debris‐covered Glacier.” Journal of Geophysical Research: Earth Surface, vol. 130, no. 6, e2025JF008360, Wiley, 2025, doi:10.1029/2025jf008360.' short: 'J.V. Melo Velasco, E. Miles, M. McCarthy, T. Shaw, C.L. Fyffe, A. Fontrodona-Bach, F. Pellicciotti, Journal of Geophysical Research: Earth Surface 130 (2025).' corr_author: '1' date_created: 2025-06-23T13:54:01Z date_published: 2025-06-15T00:00:00Z date_updated: 2025-09-30T13:42:28Z day: '15' ddc: - '550' department: - _id: FrPe doi: 10.1029/2025jf008360 external_id: isi: - '001508794200001' file: - access_level: open_access checksum: ca91541516c71d240321630ca42b4dc4 content_type: application/pdf creator: dernst date_created: 2025-06-24T06:27:34Z date_updated: 2025-06-24T06:27:34Z file_id: '19886' file_name: 2025_JGREarthSurface_MeloVelasco.pdf file_size: 3949928 relation: main_file success: 1 file_date_updated: 2025-06-24T06:27:34Z has_accepted_license: '1' intvolume: ' 130' isi: 1 issue: '6' language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: 'Journal of Geophysical Research: Earth Surface' publication_identifier: eissn: - 2169-9011 issn: - 2169-9003 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Method dependence in thermal conductivity and aerodynamic roughness length estimates on a debris‐covered glacier tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 130 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19879' abstract: - lang: eng text: We consider the 4-precoloring extension problem in planar near-Eulerian- triangulations, i.e., plane graphs where all faces except possibly for the outer one have length three, all vertices not incident with the outer face have even degree, and exactly the vertices incident with the outer face are precolored. We give a necessary topological condition for the precoloring to extend, and give a complete characterization when the outer face has length at most five and when all vertices of the outer face have odd degree and are colored using only three colors. acknowledgement: Supported by project 22-17398S (Flows and cycles in graphs on surfaces) of Czech Science Foundation. An extended abstract appeared in Proceedings of the 12th European Conference on Combinatorics, Graph Theory and Applications (EUROCOMB’23) article_number: '104138' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Zdeněk full_name: Dvořák, Zdeněk last_name: Dvořák - first_name: Benjamin full_name: Moore, Benjamin id: 6dc1a1be-bf1c-11ed-8d2b-d044840f49d6 last_name: Moore - first_name: Michaela full_name: Seifrtová, Michaela last_name: Seifrtová - first_name: Robert full_name: Šámal, Robert last_name: Šámal citation: ama: Dvořák Z, Moore B, Seifrtová M, Šámal R. Precoloring extension in planar near-Eulerian-triangulations. European Journal of Combinatorics. 2025;127. doi:10.1016/j.ejc.2025.104138 apa: Dvořák, Z., Moore, B., Seifrtová, M., & Šámal, R. (2025). Precoloring extension in planar near-Eulerian-triangulations. European Journal of Combinatorics. Elsevier. https://doi.org/10.1016/j.ejc.2025.104138 chicago: Dvořák, Zdeněk, Benjamin Moore, Michaela Seifrtová, and Robert Šámal. “Precoloring Extension in Planar Near-Eulerian-Triangulations.” European Journal of Combinatorics. Elsevier, 2025. https://doi.org/10.1016/j.ejc.2025.104138. ieee: Z. Dvořák, B. Moore, M. Seifrtová, and R. Šámal, “Precoloring extension in planar near-Eulerian-triangulations,” European Journal of Combinatorics, vol. 127. Elsevier, 2025. ista: Dvořák Z, Moore B, Seifrtová M, Šámal R. 2025. Precoloring extension in planar near-Eulerian-triangulations. European Journal of Combinatorics. 127, 104138. mla: Dvořák, Zdeněk, et al. “Precoloring Extension in Planar Near-Eulerian-Triangulations.” European Journal of Combinatorics, vol. 127, 104138, Elsevier, 2025, doi:10.1016/j.ejc.2025.104138. short: Z. Dvořák, B. Moore, M. Seifrtová, R. Šámal, European Journal of Combinatorics 127 (2025). corr_author: '1' date_created: 2025-06-23T13:54:46Z date_published: 2025-06-01T00:00:00Z date_updated: 2025-09-30T13:42:59Z day: '01' ddc: - '510' department: - _id: MaKw doi: 10.1016/j.ejc.2025.104138 external_id: arxiv: - '2312.13061' isi: - '001443061400001' file: - access_level: open_access checksum: 8b3585df45b25091fba9bee9854b7d01 content_type: application/pdf creator: dernst date_created: 2025-06-24T06:33:30Z date_updated: 2025-06-24T06:33:30Z file_id: '19887' file_name: 2025_EuropJournCombinatorics_Dvorak.pdf file_size: 564203 relation: main_file success: 1 file_date_updated: 2025-06-24T06:33:30Z has_accepted_license: '1' intvolume: ' 127' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: European Journal of Combinatorics publication_identifier: issn: - 0195-6698 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Precoloring extension in planar near-Eulerian-triangulations tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 127 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19880' abstract: - lang: eng text: We investigate quantum transport in a two-dimensional electron system coupled to a chiral molecular potential, demonstrating how molecular chirality and orientation affect charge and spin transport properties. We propose a minimal model for realizing true chiral symmetry breaking on a magnetized surface, with a crucial role played by the tilt angle of the molecular dipole with respect to the surface. For non-zero tilting, we show that the Hall response exhibits clear signatures of chirality-induced effects, in both charge- and spin-resolved observables. Concerning the former, tilted enantiomers produce asymmetric Hall conductances and, even more remarkably, the persistence of this feature in the absence of spin–orbit coupling (SOC) signals how the enantiospecific charge response results from electron scattering off the molecular potential. Concerning spin-resolved observables where SOC plays a relevant role, we reveal that chiral symmetry breaking is crucial in enabling spin-flipping processes. acknowledgement: We thank Artem Volosniev, Narcis Avarvari, Georgios Koutentakis, Sandro Wimberger, and Binghai Yan for useful discussions. R.A. received funding from the Austrian Academy of Science ÖWA, Grant No. PR1029OEAW03. M.L. acknowledges support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). A.C. received funding from the European Union’s Horizon Europe research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 101062862-NeqMolRot. article_number: '234106' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Ragheed full_name: Al Hyder, Ragheed id: d1c405be-ae15-11ed-8510-ccf53278162e last_name: Al Hyder - first_name: Mikhail full_name: Lemeshko, Mikhail id: 37CB05FA-F248-11E8-B48F-1D18A9856A87 last_name: Lemeshko orcid: 0000-0002-6990-7802 - first_name: Alberto full_name: Cappellaro, Alberto id: 9d13b3cb-30a2-11eb-80dc-f772505e8660 last_name: Cappellaro orcid: 0000-0001-6110-2359 citation: ama: Al Hyder R, Lemeshko M, Cappellaro A. Quantum transport in the presence of a chiral molecular potential. The Journal of Chemical Physics. 2025;162(23). doi:10.1063/5.0271155 apa: Al Hyder, R., Lemeshko, M., & Cappellaro, A. (2025). Quantum transport in the presence of a chiral molecular potential. The Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/5.0271155 chicago: Al Hyder, Ragheed, Mikhail Lemeshko, and Alberto Cappellaro. “Quantum Transport in the Presence of a Chiral Molecular Potential.” The Journal of Chemical Physics. AIP Publishing, 2025. https://doi.org/10.1063/5.0271155. ieee: R. Al Hyder, M. Lemeshko, and A. Cappellaro, “Quantum transport in the presence of a chiral molecular potential,” The Journal of Chemical Physics, vol. 162, no. 23. AIP Publishing, 2025. ista: Al Hyder R, Lemeshko M, Cappellaro A. 2025. Quantum transport in the presence of a chiral molecular potential. The Journal of Chemical Physics. 162(23), 234106. mla: Al Hyder, Ragheed, et al. “Quantum Transport in the Presence of a Chiral Molecular Potential.” The Journal of Chemical Physics, vol. 162, no. 23, 234106, AIP Publishing, 2025, doi:10.1063/5.0271155. short: R. Al Hyder, M. Lemeshko, A. Cappellaro, The Journal of Chemical Physics 162 (2025). corr_author: '1' date_created: 2025-06-23T13:55:28Z date_published: 2025-06-21T00:00:00Z date_updated: 2025-09-30T13:40:55Z day: '21' ddc: - '530' department: - _id: MiLe doi: 10.1063/5.0271155 ec_funded: 1 external_id: arxiv: - '2503.14124' isi: - '001512872900010' pmid: - '40526561' file: - access_level: open_access checksum: e278631d949657baa9d5309dad5f4b77 content_type: application/pdf creator: dernst date_created: 2025-06-23T14:03:30Z date_updated: 2025-06-23T14:03:30Z file_id: '19881' file_name: 2025_JourChemicalPhysics_AlHyder.pdf file_size: 7202681 relation: main_file success: 1 file_date_updated: 2025-06-23T14:03:30Z has_accepted_license: '1' intvolume: ' 162' isi: 1 issue: '23' language: - iso: eng month: '06' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 2688CF98-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '801770' name: 'Angulon: physics and applications of a new quasiparticle' - _id: bd7b5202-d553-11ed-ba76-9b1c1b258338 grant_number: '101062862' name: Non-Equilibrium Field Theory of Molecular Rotations - _id: 8fa7db46-16d5-11f0-9cad-917600954daf grant_number: '12078' name: Polarons in Lead Halide Perovskites publication: The Journal of Chemical Physics publication_identifier: eissn: - 1089-7690 issn: - 0021-9606 publication_status: published publisher: AIP Publishing quality_controlled: '1' scopus_import: '1' status: public title: Quantum transport in the presence of a chiral molecular potential tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 162 year: '2025' ... --- _id: '19885' abstract: - lang: eng text: This .zip file contains the data to reproduce the figures and supplementary figures of "Automated All-RF Tuning for Spin Qubit Readout and Control" by Cornelius Carlsson and Jaime Saez-Mollejo et al. acknowledged_ssus: - _id: M-Shop - _id: NanoFab acknowledgement: 'The authors would like to thank Barnaby van Straaten, Jonas Schuff, Daniel Jirovec and Hanifa Tidjani for fruitful discussions. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication Facility. G.K. acknowledges support from the NOMIS Foundation, the HORIZON-RIA (project no. 101069515) and the FWF Projects (DOIs: 10.55776/F86 and 10.55776/I5060). N.A. acknowledges support from the European Research Council (grant agreement 948932), and the Royal Society (grant no. URF/R1/191150). This project received support from the US Army Research Office (ARO) under Award No. W911NF-24-2-0043. C.C. acknowledges support from the UKRI Doctoral Training Partnership related to EP/W524311/1 (project ref. 2887634).' article_processing_charge: No author: - first_name: Jaime full_name: Saez Mollejo, Jaime id: e0390f72-f6e0-11ea-865d-862393336714 last_name: Saez Mollejo citation: ama: Saez Mollejo J. Automated All-RF Tuning for Spin Qubit Readout and Control. 2025. doi:10.15479/AT:ISTA:19885 apa: Saez Mollejo, J. (2025). Automated All-RF Tuning for Spin Qubit Readout and Control. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:19885 chicago: Saez Mollejo, Jaime. “Automated All-RF Tuning for Spin Qubit Readout and Control.” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT:ISTA:19885. ieee: J. Saez Mollejo, “Automated All-RF Tuning for Spin Qubit Readout and Control.” Institute of Science and Technology Austria, 2025. ista: Saez Mollejo J. 2025. Automated All-RF Tuning for Spin Qubit Readout and Control, Institute of Science and Technology Austria, 10.15479/AT:ISTA:19885. mla: Saez Mollejo, Jaime. Automated All-RF Tuning for Spin Qubit Readout and Control. Institute of Science and Technology Austria, 2025, doi:10.15479/AT:ISTA:19885. short: J. Saez Mollejo, (2025). contributor: - contributor_type: researcher first_name: Cornelius last_name: Carlsson - contributor_type: researcher first_name: 'Federico ' last_name: Fedele - contributor_type: researcher first_name: Stefano last_name: Calcaterra - contributor_type: researcher first_name: ' Daniel ' last_name: Chrastina - contributor_type: researcher first_name: 'Giovanni ' last_name: Isella - contributor_type: researcher first_name: Georgios id: 38DB5788-F248-11E8-B48F-1D18A9856A87 last_name: Katsaros orcid: 0000-0001-8342-202X - contributor_type: researcher first_name: Natalia last_name: Ares corr_author: '1' date_created: 2025-06-24T06:56:03Z date_published: 2025-06-01T00:00:00Z date_updated: 2025-07-01T07:19:26Z day: '01' ddc: - '530' department: - _id: GradSch - _id: GeKa doi: 10.15479/AT:ISTA:19885 file: - access_level: open_access checksum: eff1ae9e46599fdfab8da00a2ca3c289 content_type: application/x-zip-compressed creator: jsaezmol date_created: 2025-06-24T15:14:13Z date_updated: 2025-06-24T15:14:13Z file_id: '19893' file_name: DatasetsPaper.zip file_size: 3404814792 relation: main_file success: 1 - access_level: open_access checksum: 21840ceac04d677a799b8e5bd919804f content_type: text/plain creator: jsaezmol date_created: 2025-06-25T07:11:52Z date_updated: 2025-06-25T07:11:52Z file_id: '19899' file_name: README.txt file_size: 622 relation: main_file success: 1 file_date_updated: 2025-06-25T07:11:52Z has_accepted_license: '1' month: '06' oa: 1 oa_version: Published Version project: - _id: 34c0acea-11ca-11ed-8bc3-8775e10fd452 grant_number: '101069515' name: Integrated Germanium Quantum Technology - _id: c0977eea-5a5b-11eb-8a69-a862db0cf4d1 grant_number: I05060 name: High impedance circuit quantum electrodynamics with hole spins - _id: 34a66131-11ca-11ed-8bc3-a31681c6b03e grant_number: F8606 name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems: Conventional and unconventional topological superconductors' publisher: Institute of Science and Technology Austria status: public title: Automated All-RF Tuning for Spin Qubit Readout and Control tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: research_data user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2025' ... --- _id: '19915' acknowledgement: "We thank all members of the Martin Loose lab at ISTA for helpful discussions and Marko Kojic for critical reading of the manuscript. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp) and the Electron Microscopy Facility (EMF), as well as the Lab Support Facility (LSF). This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No.101034413 awarded to BLS as well as an ERC grant (ActinID, 101076260) from the European Union awarded to FKMS. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them.\r\n\r\nWe are grateful for Antonia Herrero (Sevilla University) for sharing her extensive BACTH plasmid library and other plasmids as well as cyanobacterial strains. Likewise, we would like to thank Tal Dagan and Fabian Nies (both Kiel University) for sharing cyanobacterial strains and plasmids and for valuable discussions.\r\n\r\nWe would further like to express our gratitude to Nicolas Sapay and Alexis Michon for providing the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix screen of cyanobacterial CorR proteins. Finally, we also want to thank Jesse Hansen for advice in cryo-EM data processing" article_processing_charge: No author: - first_name: Benjamin L full_name: Springstein, Benjamin L id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083 last_name: Springstein orcid: 0000-0002-3461-5391 citation: ama: Springstein BL. Files for “Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape.” 2025. doi:10.15479/AT:ISTA:19915 apa: Springstein, B. L. (2025). Files for “Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:19915 chicago: Springstein, Benjamin L. “Files for ‘Evolutionary Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cyanobacterial Cell Shape.’” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT:ISTA:19915. ieee: B. L. Springstein, “Files for ‘Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape.’” Institute of Science and Technology Austria, 2025. ista: Springstein BL. 2025. Files for ‘Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape’, Institute of Science and Technology Austria, 10.15479/AT:ISTA:19915. mla: Springstein, Benjamin L. Files for “Evolutionary Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cyanobacterial Cell Shape.” Institute of Science and Technology Austria, 2025, doi:10.15479/AT:ISTA:19915. short: B.L. Springstein, (2025). contributor: - contributor_type: project_leader first_name: Benjamin L id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083 last_name: Springstein orcid: 0000-0002-3461-5391 - contributor_type: researcher first_name: Manjunath id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2 last_name: Javoor - contributor_type: researcher first_name: Daniela last_name: Megrian - contributor_type: researcher first_name: Roman id: ffab949d-133f-11ed-8f02-94de21ace503 last_name: Hajdu - contributor_type: researcher first_name: Dustin M last_name: Hanke - contributor_type: researcher first_name: Florian KM id: 48AD8942-F248-11E8-B48F-1D18A9856A87 last_name: Schur orcid: 0000-0003-4790-8078 - contributor_type: supervisor first_name: Martin id: 462D4284-F248-11E8-B48F-1D18A9856A87 last_name: Loose orcid: 0000-0001-7309-9724 corr_author: '1' date_created: 2025-06-27T07:34:52Z date_published: 2025-06-27T00:00:00Z date_updated: 2025-07-02T08:25:37Z day: '27' department: - _id: MaLo doi: 10.15479/AT:ISTA:19915 ec_funded: 1 file: - 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access_level: open_access checksum: 8d252711086b99123bd47a20a1bb96c5 content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:19Z date_updated: 2025-07-02T08:10:19Z file_id: '19948' file_name: Supplementary Figure 3.pdf file_size: 2130970 relation: main_file success: 1 - access_level: open_access checksum: c038000e7b5b1fed77888bcba8268e3a content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:19Z date_updated: 2025-07-02T08:10:19Z file_id: '19949' file_name: Supplementary Figure 4.pdf file_size: 583089 relation: main_file success: 1 - access_level: open_access checksum: 73e4ae52520ff1037336fd088139872f content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:19Z date_updated: 2025-07-02T08:10:19Z file_id: '19950' file_name: Supplementary Figure 5.pdf file_size: 81663 relation: main_file success: 1 - access_level: open_access checksum: b5e75fda4fc9a2599972341777a8de4b content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:20Z date_updated: 2025-07-02T08:10:20Z file_id: '19951' file_name: Supplementary Figure 6.pdf file_size: 19661623 relation: main_file success: 1 - access_level: open_access checksum: aab9ea12e09c12a97d33e3d2d44471e7 content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:20Z date_updated: 2025-07-02T08:10:20Z file_id: '19952' file_name: Supplementary Figure 7.pdf file_size: 3756335 relation: main_file success: 1 - access_level: open_access checksum: b4c7b6947a0aa2840b7dacc1489896df content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:20Z date_updated: 2025-07-02T08:10:20Z file_id: '19953' file_name: Supplementary Figure 8.pdf file_size: 3216820 relation: main_file success: 1 - access_level: open_access checksum: 8423814c4dfefad5757835aab8295b2e content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:21Z date_updated: 2025-07-02T08:10:21Z file_id: '19954' file_name: Supplementary Figure 9.pdf file_size: 7449121 relation: main_file success: 1 - access_level: open_access checksum: 31ecac7daf4b50e2ea443f398fdc2110 content_type: application/pdf creator: bsprings date_created: 2025-07-02T08:10:21Z date_updated: 2025-07-02T08:10:21Z file_id: '19955' file_name: Supplementary Figure 10.pdf file_size: 6168864 relation: main_file success: 1 file_date_updated: 2025-07-02T08:10:21Z has_accepted_license: '1' month: '06' oa: 1 oa_version: None project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' - _id: bd980d18-d553-11ed-ba76-ceaa645c97eb grant_number: '101076260' name: A molecular atlas of Actin filament IDentities in the cell motility machinery publisher: Institute of Science and Technology Austria status: public title: Files for "Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape" tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: research_data user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '19928' abstract: - lang: eng text: 'Patho-mechanistic origins of ulcerative colitis are still poorly understood. The actin cross-linker filamin A (FLNA) impacts cellular responses through interaction with cytosolic proteins. Posttranscriptional A-to-I editing generates two forms of FLNA: genome-encoded FLNAQ and FLNAR. FLNA is edited in colon fibroblasts, smooth muscle cells, and endothelial cells. We found that the FLNA editing status determines colitis severity. Editing was highest in healthy colons and reduced during murine and human colitis. Mice that exclusively express FLNAR were highly resistant to DSS-induced colitis, whereas fully FLNAQ animals developed severe inflammation. While the genetic induction of FLNA editing influenced transcriptional states of structural cells and microbiome composition, we found that FLNAR exerts protection specifically via myeloid cells, which are physiologically unedited. Introducing fixed FLNAR did not hamper cell migration but reduced macrophage inflammation and rendered neutrophils less prone to NETosis. Thus, loss of FLNA editing correlates with colitis severity, and targeted editing of myeloid cells serves as a novel therapeutic approach in intestinal inflammation.' acknowledgement: "Sequencing was performed by the Vienna BioCenter Core Facilities (Medical University of Vienna Core Facility) and the Biomedical Sequencing Facility at CeMM, Vienna. Cell sorting and flow cytometry were performed at the Core Facility Flow Cytometry and Imaging (Medical University of Vienna). We thank Jasmin Schwarz, Gudrun Kohl, Petra Pjevac, and Joana Seneca Silva from the Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna for assisting with amplicon and metagenomic sequencing, as well as repositing of sequencing data. We thank Sophia Derdak and Michael Schuster for initial data analysis, Robert Vilvoi and Stephan Hemm for animal handling, Marcel Kertesz for mouse genotyping, and Salwan Roumaia for next generation sequencing sample preparation. Treatment schemes and graphical abstracts were created with https://BioRender.com.\r\n\r\nThis work was supported by the Austrian Science Fund, grant number ZK 57-B28 to C. Vesely, R. Gawish, and F.C. Pereira; grant number V 1025-B to R. Gawish; grant number DOC32-B28 to R. Varada and M.F. Jantsch; and F8007 and P32678 to M.F. Jantsch. Open Access funding provided by Medical University of Vienna." article_number: e20240109 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Riem full_name: Gawish, Riem last_name: Gawish - first_name: Rajagopal full_name: Varada, Rajagopal last_name: Varada - first_name: Florian full_name: Deckert, Florian last_name: Deckert - first_name: Anastasiya full_name: Hladik, Anastasiya last_name: Hladik - first_name: Linda full_name: Steinbichl, Linda last_name: Steinbichl - first_name: Laura full_name: Cimatti, Laura last_name: Cimatti - first_name: Katarina full_name: Milanovic, Katarina last_name: Milanovic - first_name: Mamta full_name: Jain, Mamta last_name: Jain - first_name: Natalya full_name: Torgasheva, Natalya last_name: Torgasheva - first_name: Andrea full_name: Tanzer, Andrea last_name: Tanzer - first_name: Kim full_name: De Paepe, Kim last_name: De Paepe - first_name: Tom full_name: Van De Wiele, Tom last_name: Van De Wiele - first_name: Bela full_name: Hausmann, Bela last_name: Hausmann - first_name: Michaela full_name: Lang, Michaela last_name: Lang - first_name: Martin full_name: Pechhacker, Martin last_name: Pechhacker - first_name: Nahla full_name: Ibrahim, Nahla last_name: Ibrahim - first_name: Ingrid full_name: De Vries, Ingrid id: 4C7D837E-F248-11E8-B48F-1D18A9856A87 last_name: De Vries - first_name: Christine full_name: Brostjan, Christine last_name: Brostjan - first_name: Michael K full_name: Sixt, Michael K id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87 last_name: Sixt orcid: 0000-0002-6620-9179 - first_name: Christoph full_name: Gasche, Christoph last_name: Gasche - first_name: Louis full_name: Boon, Louis last_name: Boon - first_name: David full_name: Berry, David last_name: Berry - first_name: Michael F. full_name: Jantsch, Michael F. last_name: Jantsch - first_name: Fatima C. full_name: Pereira, Fatima C. last_name: Pereira - first_name: Cornelia full_name: Vesely, Cornelia last_name: Vesely citation: ama: Gawish R, Varada R, Deckert F, et al. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. 2025;222(9). doi:10.1084/jem.20240109 apa: Gawish, R., Varada, R., Deckert, F., Hladik, A., Steinbichl, L., Cimatti, L., … Vesely, C. (2025). Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. Rockefeller University Press. https://doi.org/10.1084/jem.20240109 chicago: Gawish, Riem, Rajagopal Varada, Florian Deckert, Anastasiya Hladik, Linda Steinbichl, Laura Cimatti, Katarina Milanovic, et al. “Filamin A Editing in Myeloid Cells Reduces Intestinal Inflammation and Protects from Colitis.” Journal of Experimental Medicine. Rockefeller University Press, 2025. https://doi.org/10.1084/jem.20240109. ieee: R. Gawish et al., “Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis,” Journal of Experimental Medicine, vol. 222, no. 9. Rockefeller University Press, 2025. ista: Gawish R, Varada R, Deckert F, Hladik A, Steinbichl L, Cimatti L, Milanovic K, Jain M, Torgasheva N, Tanzer A, De Paepe K, Van De Wiele T, Hausmann B, Lang M, Pechhacker M, Ibrahim N, de Vries I, Brostjan C, Sixt MK, Gasche C, Boon L, Berry D, Jantsch MF, Pereira FC, Vesely C. 2025. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. 222(9), e20240109. mla: Gawish, Riem, et al. “Filamin A Editing in Myeloid Cells Reduces Intestinal Inflammation and Protects from Colitis.” Journal of Experimental Medicine, vol. 222, no. 9, e20240109, Rockefeller University Press, 2025, doi:10.1084/jem.20240109. short: R. Gawish, R. Varada, F. Deckert, A. Hladik, L. Steinbichl, L. Cimatti, K. Milanovic, M. Jain, N. Torgasheva, A. Tanzer, K. De Paepe, T. Van De Wiele, B. Hausmann, M. Lang, M. Pechhacker, N. Ibrahim, I. de Vries, C. Brostjan, M.K. Sixt, C. Gasche, L. Boon, D. Berry, M.F. Jantsch, F.C. Pereira, C. Vesely, Journal of Experimental Medicine 222 (2025). date_created: 2025-06-29T22:01:15Z date_published: 2025-09-01T00:00:00Z date_updated: 2025-12-30T09:00:42Z day: '01' ddc: - '570' department: - _id: MiSi doi: 10.1084/jem.20240109 external_id: isi: - '001502896900001' pmid: - '40471139' file: - access_level: open_access checksum: 708d61fb8cf1d83ee1e33ddcfde0857e content_type: application/pdf creator: dernst date_created: 2025-12-30T09:00:04Z date_updated: 2025-12-30T09:00:04Z file_id: '20899' file_name: 2025_JEM_Gawish.pdf file_size: 9349311 relation: main_file success: 1 file_date_updated: 2025-12-30T09:00:04Z has_accepted_license: '1' intvolume: ' 222' isi: 1 issue: '9' language: - iso: eng month: '09' oa: 1 oa_version: Published Version pmid: 1 publication: Journal of Experimental Medicine publication_identifier: eissn: - 1540-9538 issn: - 0022-1007 publication_status: published publisher: Rockefeller University Press quality_controlled: '1' scopus_import: '1' status: public title: Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 222 year: '2025' ... --- OA_place: publisher OA_type: diamond _id: '19929' abstract: - lang: eng text: "Context. The observed Lyman-alpha (Lyα) line profile is a convolution of the complex Lyα radiative transfer taking place in the interstellar, circumgalactic, and intergalactic media (ISM, CGM, and IGM, respectively). Discerning the different components of the Lyα line is crucial in order to use it as a probe of galaxy formation or the evolution of the IGM.\r\n\r\nAims. We aim to present the second version of zELDA (redshift Estimator for Line profiles of Distant Lyman-Alpha emitters), an open-source Python module focused on modelling and fitting observed Lyα line profiles. This new version of zELDA focuses on disentangling the galactic from the IGM effects.\r\n\r\nMethods. We built realistic Lyα line profiles that include the ISM and IGM contributions by combining the Monte Carlo radiative-transfer simulations for the so-called shell model (ISM) and IGM transmission curves generated from TNG100. We used these mock line profiles to train different artificial neural networks. These use the observed spectrum as input and the outflow parameters of the best fitting ‘shell model’ as output along with the redshift and Lyα emission IGM escape fraction of the source.\r\n\r\nResults. We measured the accuracy of zELDA on mock Lyα line profiles. We find that zELDA is capable of reconstructing the ISM emerging Lyα line profile with high levels of accuracy (Kolmogórov-Smirnov<0.1) for 95% of the cases for HST/COS-like observations and 80% for MUSE-WIDE-like observations. zELDA is able to measure the IGM transmission with typical uncertainties below 10% for HST/COS and MUSE-WIDE data.\r\n\r\nConclusions. This work represents a step forward in the high-precision reconstruction of IGM-attenuated Lyα line profiles. zELDA allows the disentanglement of the galactic and IGM contribution shaping the Lyα line shape and thus allows us to use Lyα as a tool to study galaxy and ISM evolution." acknowledgement: The authors acknowledge the financial support from the MICIU with funding from the European Union NextGenerationEU and Generalitat Valenciana in the call Programa de Planes Complementarios de I+D+i (PRTR 2022) Project (VAL-JPAS), reference ASFAE/2022/025. This work is part of the research Project PID2023-149420NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU. This work is also supported by the project of excellence PROMETEO CIPROM/2023/21 of the Conselleria de Educación, Universidades y Empleo (Generalitat Valenciana). MG thanks the Max Planck Society for support through the Max Planck Research Group. DS acknowledges the support by the Tsinghua Shui Mu Scholarship, funding of the National Key R&D Program of China (grant no. 2023YFA1605600), the science research grants from the China Manned Space Project with no. CMS-CSST2021-A05, and the Tsinghua University Initiative Scientific Research Program (no. 20223080023). This research made use of matplotlib, a Python library for publication quality graphics (Hunter 2007), NumPy (Harris et al. 2020) and SciPy (Virtanen et al. 2020). article_number: A139 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Siddhartha full_name: Gurung-López, Siddhartha last_name: Gurung-López - first_name: Chris full_name: Byrohl, Chris last_name: Byrohl - first_name: Max full_name: Gronke, Max last_name: Gronke - first_name: Daniele full_name: Spinoso, Daniele last_name: Spinoso - first_name: Alberto full_name: Torralba Torregrosa, Alberto id: 018f0249-0e87-11f0-b167-cbce08fbd541 last_name: Torralba Torregrosa orcid: 0000-0001-5586-6950 - first_name: Alberto full_name: Fernández-Soto, Alberto last_name: Fernández-Soto - first_name: Pablo full_name: Arnalte-Mur, Pablo last_name: Arnalte-Mur - first_name: Vicent J. full_name: Martínez, Vicent J. last_name: Martínez citation: ama: 'Gurung-López S, Byrohl C, Gronke M, et al. zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. Astronomy & Astrophysics. 2025;698. doi:10.1051/0004-6361/202453547' apa: 'Gurung-López, S., Byrohl, C., Gronke, M., Spinoso, D., Torralba Torregrosa, A., Fernández-Soto, A., … Martínez, V. J. (2025). zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202453547' chicago: 'Gurung-López, Siddhartha, Chris Byrohl, Max Gronke, Daniele Spinoso, Alberto Torralba Torregrosa, Alberto Fernández-Soto, Pablo Arnalte-Mur, and Vicent J. Martínez. “ZELDA II: Reconstruction of Galactic Lyman-Alpha Spectra Attenuated by the Intergalactic Medium Using Neural Networks.” Astronomy & Astrophysics. EDP Sciences, 2025. https://doi.org/10.1051/0004-6361/202453547.' ieee: 'S. Gurung-López et al., “zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks,” Astronomy & Astrophysics, vol. 698. EDP Sciences, 2025.' ista: 'Gurung-López S, Byrohl C, Gronke M, Spinoso D, Torralba Torregrosa A, Fernández-Soto A, Arnalte-Mur P, Martínez VJ. 2025. zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks. Astronomy & Astrophysics. 698, A139.' mla: 'Gurung-López, Siddhartha, et al. “ZELDA II: Reconstruction of Galactic Lyman-Alpha Spectra Attenuated by the Intergalactic Medium Using Neural Networks.” Astronomy & Astrophysics, vol. 698, A139, EDP Sciences, 2025, doi:10.1051/0004-6361/202453547.' short: S. Gurung-López, C. Byrohl, M. Gronke, D. Spinoso, A. Torralba Torregrosa, A. Fernández-Soto, P. Arnalte-Mur, V.J. Martínez, Astronomy & Astrophysics 698 (2025). date_created: 2025-06-29T22:01:15Z date_published: 2025-06-01T00:00:00Z date_updated: 2026-02-16T12:11:56Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1051/0004-6361/202453547 external_id: arxiv: - '2501.04077' isi: - '001507317300003' file: - access_level: open_access checksum: a50a817b72f03534c6a867035b51e433 content_type: application/pdf creator: dernst date_created: 2025-06-30T08:28:40Z date_updated: 2025-06-30T08:28:40Z file_id: '19933' file_name: 2025_AstronomyAstrophysics_GurungLopez.pdf file_size: 5758102 relation: main_file success: 1 file_date_updated: 2025-06-30T08:28:40Z has_accepted_license: '1' intvolume: ' 698' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: Astronomy & Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: 'zELDA II: Reconstruction of galactic Lyman-alpha spectra attenuated by the intergalactic medium using neural networks' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 698 year: '2025' ... --- OA_place: publisher OA_type: diamond _id: '19930' abstract: - lang: eng text: We present an analysis of the UV continuum slope, β, using a sample of 726 galaxies with z > 4, selected from a mixture of JWST ERS, GTO, and GO observational programs. We considered only spectroscopic data obtained with the low-resolution (R ∼ 30 − 300) PRISM/CLEAR NIRSpec configuration. Studying the correlation between β and MUV, we find an overall decreasing trend, described by β = ( − 0.055 ± 0.017)MUV + ( − 2.98 ± 0.34). This is consistent with previous studies, where brighter galaxies show redder β values. However, when analyzing the trend in separate redshift bins, we find that at high redshift the relation becomes much flatter and is consistent with a flat slope within 1σ. Furthermore, we find that β tends to decrease with redshift, following β = ( − 0.075 ± 0.010)z + ( − 1.496 ± 0.056). This is consistent with most recent results showing a steepening of the spectra at higher z. We selected a sample of galaxies with extremely blue slopes (i.e., β < −2.6). Such slopes are steeper than predicted by stellar evolution models – even for dust-free, young, metal-poor populations – when the contribution of nebular emission is included. We selected 44 extremely blue galaxies (XBGs) and investigated the possible physical origin of their steep slopes by comparing them to a subsample of redder galaxies (matched in Δz = ±0.5 and ΔMUV = ±0.2). We find that XBGs have younger stellar populations, stronger ionization fields, lower dust attenuation, and lower but not pristine metallicity (∼10% Z⊙) compared to red galaxies. However, these properties alone cannot explain the extreme β values. Using indirect inference of Lyman continuum escape with the most recent models, we estimated the escape fraction fesc > 10% in at least 25% of the XBGs, whereas all the red sources exhibit much lower fesc values. A reduced nebular continuum contribution – resulting from either a high escape fraction or a bursty star formation history – is likely the origin of the extremely blue slopes. acknowledgement: We acknowledges support from the INAF Large Grant for Extragalactic Surveys with JWST and from the PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU. PS acknowledges INAF Mini Grant 2022 “The evolution of passive galaxies through cosmic time”. Part of the research activities described in this paper were carried out with the contribution of the Next Generation EU funds within the National Recovery and Resilience Plan (PNRR), Mission 4 – Education and Research, Component 2 – From Research to Business (M4C2), Investment Line 3.1 – Strengthening and creation of Research Infrastructures, Project IR0000034 – “STILES – Strengthening the Italian Leadership in ELT and SKA”. RA acknowledges support of Grant project PID2023-147386NB-I00 funded by MICIU/AEI/10.13039/501100011033 and by ERDF/EU, and the Severo Ochoa grant CEX2021-001131-S funded by MCIN/AEI/10.13039/50110001103. article_number: A234 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: D. full_name: Dottorini, D. last_name: Dottorini - first_name: A. full_name: Calabrò, A. last_name: Calabrò - first_name: L. full_name: Pentericci, L. last_name: Pentericci - first_name: Sara full_name: Mascia, Sara id: edaf889c-c7cd-11ef-ab1b-bb28c431bd29 last_name: Mascia - first_name: M. full_name: Llerena, M. last_name: Llerena - first_name: L. full_name: Napolitano, L. last_name: Napolitano - first_name: P. full_name: Santini, P. last_name: Santini - first_name: G. full_name: Roberts-Borsani, G. last_name: Roberts-Borsani - first_name: M. full_name: Castellano, M. last_name: Castellano - first_name: R. full_name: Amorin, R. last_name: Amorin - first_name: M. full_name: Dickinson, M. last_name: Dickinson - first_name: A. full_name: Fontana, A. last_name: Fontana - first_name: N. full_name: Hathi, N. last_name: Hathi - first_name: M. full_name: Hirschmann, M. last_name: Hirschmann - first_name: A. M. full_name: Koekemoer, A. M. last_name: Koekemoer - first_name: R. A. full_name: Lucas, R. A. last_name: Lucas - first_name: E. full_name: Merlin, E. last_name: Merlin - first_name: A. full_name: Morales, A. last_name: Morales - first_name: F. full_name: Pacucci, F. last_name: Pacucci - first_name: S. full_name: Wilkins, S. last_name: Wilkins - first_name: P. full_name: Arrabal Haro, P. last_name: Arrabal Haro - first_name: M. full_name: Bagley, M. last_name: Bagley - first_name: S. L. full_name: Finkelstein, S. L. last_name: Finkelstein - first_name: J. full_name: Kartaltepe, J. last_name: Kartaltepe - first_name: C. full_name: Papovich, C. last_name: Papovich - first_name: N. full_name: Pirzkal, N. last_name: Pirzkal citation: ama: 'Dottorini D, Calabrò A, Pentericci L, et al. Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies. Astronomy & Astrophysics. 2025;698. doi:10.1051/0004-6361/202453267' apa: 'Dottorini, D., Calabrò, A., Pentericci, L., Mascia, S., Llerena, M., Napolitano, L., … Pirzkal, N. (2025). Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202453267' chicago: 'Dottorini, D., A. Calabrò, L. Pentericci, Sara Mascia, M. Llerena, L. Napolitano, P. Santini, et al. “Evolution of the UV Slope of Galaxies at Cosmic Morning (z > 4): The Properties of Extremely Blue Galaxies.” Astronomy & Astrophysics. EDP Sciences, 2025. https://doi.org/10.1051/0004-6361/202453267.' ieee: 'D. Dottorini et al., “Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies,” Astronomy & Astrophysics, vol. 698. EDP Sciences, 2025.' ista: 'Dottorini D, Calabrò A, Pentericci L, Mascia S, Llerena M, Napolitano L, Santini P, Roberts-Borsani G, Castellano M, Amorin R, Dickinson M, Fontana A, Hathi N, Hirschmann M, Koekemoer AM, Lucas RA, Merlin E, Morales A, Pacucci F, Wilkins S, Arrabal Haro P, Bagley M, Finkelstein SL, Kartaltepe J, Papovich C, Pirzkal N. 2025. Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies. Astronomy & Astrophysics. 698, A234.' mla: 'Dottorini, D., et al. “Evolution of the UV Slope of Galaxies at Cosmic Morning (z > 4): The Properties of Extremely Blue Galaxies.” Astronomy & Astrophysics, vol. 698, A234, EDP Sciences, 2025, doi:10.1051/0004-6361/202453267.' short: D. Dottorini, A. Calabrò, L. Pentericci, S. Mascia, M. Llerena, L. Napolitano, P. Santini, G. Roberts-Borsani, M. Castellano, R. Amorin, M. Dickinson, A. Fontana, N. Hathi, M. Hirschmann, A.M. Koekemoer, R.A. Lucas, E. Merlin, A. Morales, F. Pacucci, S. Wilkins, P. Arrabal Haro, M. Bagley, S.L. Finkelstein, J. Kartaltepe, C. Papovich, N. Pirzkal, Astronomy & Astrophysics 698 (2025). date_created: 2025-06-29T22:01:15Z date_published: 2025-06-01T00:00:00Z date_updated: 2026-02-16T12:11:39Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1051/0004-6361/202453267 external_id: arxiv: - '2412.01623' isi: - '001510826300019' file: - access_level: open_access checksum: 100f897d468de9d0113277c870035b62 content_type: application/pdf creator: dernst date_created: 2025-06-30T08:22:08Z date_updated: 2025-06-30T08:22:08Z file_id: '19932' file_name: 2025_AstronomyAstrophysics_Dottorini.pdf file_size: 2442076 relation: main_file success: 1 file_date_updated: 2025-06-30T08:22:08Z has_accepted_license: '1' intvolume: ' 698' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: Astronomy & Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: 'Evolution of the UV slope of galaxies at cosmic morning (z > 4): The properties of extremely blue galaxies' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 698 year: '2025' ... --- OA_place: publisher OA_type: diamond _id: '19931' abstract: - lang: eng text: JWST observations have uncovered a new population of red, compact objects at high redshifts dubbed “little red dots” (LRDs), which typically show broad emission lines and are thought to be dusty active galactic nuclei (AGNs). Some of their other features, however, challenge the AGN explanation, such as prominent Balmer breaks and extremely faint or even missing metal high-ionization lines, X-ray, or radio emission, including in deep stacks. Time variability is another robust test of AGN activity. Here, we exploit the z = 7.045 multiply imaged LRD A2744-QSO1, which offers a particularly unique test of variability due to lensing-induced time delays between the three images spanning 22 yr (2.7 yr in the rest-frame), to investigate its photometric and spectroscopic variability. We find the equivalent widths (EWs) of the broad Hα and Hβ lines, which are independent of magnification and other systematics, to exhibit significant variations, of up to 18 ± 3% for Hα and up to 22 ± 8% in Hβ, on a timescale of 875 d (2.4 yr) in the rest-frame. This suggests that A2744-QSO1 is indeed an AGN. We find no significant photometric variability beyond the limiting systematic uncertainties, so it currently cannot be determined whether the EW variations are due to line-flux or continuum variability. These results are consistent with a typical damped random walk variability model for an AGN such as A2744-QSO1 (MBH = 4 × 107 M⊙) given the sparse sampling of the light curve with the available data. Our results therefore support the AGN interpretation of this LRD, and highlight the need for further photometric and spectroscopic monitoring in order to build a detailed and reliable light curve. acknowledgement: 'We would like to thank Xihan Ji, Hannah Übler, and Roberto Maiolino, for cordial and useful discussions. The BGU lensing group acknowledges support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Israel Science Foundation Grant No. 864/23. P.D. warmly thanks the European Commission’s and University of Groningen’s CO-FUND Rosalind Franklin program. This work is based on observations obtained with the NASA/ESA/CSA JWST, namely programs GO-2756, -2561, -2883, -3538, -4111, and -3516, retrieved from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI). STScI is operated by the Association of Universities for Research in Astronomy, Inc. under NASA contract NAS 5-26555. The spectroscopy products presented herein, from JWST program GO-2561, were retrieved from the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is funded by the Danish National Research Foundation under grant DNRF140. The data used in this work may be retrieved from the MAST archive at: http://dx.doi.org/10.17909/p7t7-te67. This work also makes use of the Center for Computational Astrophysics at the Flatiron Institute which is supported by the Simons Foundation. Support for JWST programs GO-2561, -4111, and -3516 was provided by NASA through grants from STScI. This research made use of Astropy, (http://www.astropy.org) a community-developed core Python package for Astronomy (Astropy Collaboration 2013, 2018) and Photutils, an Astropy package for detection and photometry of astronomical sources (Bradley et al. 2024), as well as the packages NumPy (van der Walt et al. 2011), SciPy (Virtanen et al. 2020), Matplotlib (Hunter 2007), and the MAAT Astronomy and Astrophysics tools for MATLAB (Ofek 2014).' article_number: A227 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Lukas J. full_name: Furtak, Lukas J. last_name: Furtak - first_name: Amy R. full_name: Secunda, Amy R. last_name: Secunda - first_name: Jenny E. full_name: Greene, Jenny E. last_name: Greene - first_name: Adi full_name: Zitrin, Adi last_name: Zitrin - first_name: Ivo full_name: Labbé, Ivo last_name: Labbé - first_name: Miriam full_name: Golubchik, Miriam last_name: Golubchik - first_name: Rachel full_name: Bezanson, Rachel last_name: Bezanson - first_name: Vasily full_name: Kokorev, Vasily last_name: Kokorev - first_name: Hakim full_name: Atek, Hakim last_name: Atek - first_name: Gabriel B. full_name: Brammer, Gabriel B. last_name: Brammer - first_name: Iryna full_name: Chemerynska, Iryna last_name: Chemerynska - first_name: Sam E. full_name: Cutler, Sam E. last_name: Cutler - first_name: Pratika full_name: Dayal, Pratika last_name: Dayal - first_name: Robert full_name: Feldmann, Robert last_name: Feldmann - first_name: Seiji full_name: Fujimoto, Seiji last_name: Fujimoto - first_name: Karl full_name: Glazebrook, Karl last_name: Glazebrook - first_name: Joel full_name: Leja, Joel last_name: Leja - first_name: Yilun full_name: Ma, Yilun last_name: Ma - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Erica J. full_name: Nelson, Erica J. last_name: Nelson - first_name: Pascal A. full_name: Oesch, Pascal A. last_name: Oesch - first_name: Richard full_name: Pan, Richard last_name: Pan - first_name: Sedona H. full_name: Price, Sedona H. last_name: Price - first_name: Katherine A. full_name: Suess, Katherine A. last_name: Suess - first_name: Bingjie full_name: Wang, Bingjie last_name: Wang - first_name: John R. full_name: Weaver, John R. last_name: Weaver - first_name: Katherine E. full_name: Whitaker, Katherine E. last_name: Whitaker citation: ama: Furtak LJ, Secunda AR, Greene JE, et al. Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. Astronomy & Astrophysics. 2025;698. doi:10.1051/0004-6361/202554110 apa: Furtak, L. J., Secunda, A. R., Greene, J. E., Zitrin, A., Labbé, I., Golubchik, M., … Whitaker, K. E. (2025). Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202554110 chicago: Furtak, Lukas J., Amy R. Secunda, Jenny E. Greene, Adi Zitrin, Ivo Labbé, Miriam Golubchik, Rachel Bezanson, et al. “Investigating Photometric and Spectroscopic Variability in the Multiply Imaged Little Red Dot A2744-QSO1.” Astronomy & Astrophysics. EDP Sciences, 2025. https://doi.org/10.1051/0004-6361/202554110. ieee: L. J. Furtak et al., “Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1,” Astronomy & Astrophysics, vol. 698. EDP Sciences, 2025. ista: Furtak LJ, Secunda AR, Greene JE, Zitrin A, Labbé I, Golubchik M, Bezanson R, Kokorev V, Atek H, Brammer GB, Chemerynska I, Cutler SE, Dayal P, Feldmann R, Fujimoto S, Glazebrook K, Leja J, Ma Y, Matthee JJ, Naidu RP, Nelson EJ, Oesch PA, Pan R, Price SH, Suess KA, Wang B, Weaver JR, Whitaker KE. 2025. Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1. Astronomy & Astrophysics. 698, A227. mla: Furtak, Lukas J., et al. “Investigating Photometric and Spectroscopic Variability in the Multiply Imaged Little Red Dot A2744-QSO1.” Astronomy & Astrophysics, vol. 698, A227, EDP Sciences, 2025, doi:10.1051/0004-6361/202554110. short: L.J. Furtak, A.R. Secunda, J.E. Greene, A. Zitrin, I. Labbé, M. Golubchik, R. Bezanson, V. Kokorev, H. Atek, G.B. Brammer, I. Chemerynska, S.E. Cutler, P. Dayal, R. Feldmann, S. Fujimoto, K. Glazebrook, J. Leja, Y. Ma, J.J. Matthee, R.P. Naidu, E.J. Nelson, P.A. Oesch, R. Pan, S.H. Price, K.A. Suess, B. Wang, J.R. Weaver, K.E. Whitaker, Astronomy & Astrophysics 698 (2025). date_created: 2025-06-29T22:01:16Z date_published: 2025-06-01T00:00:00Z date_updated: 2026-02-16T12:11:22Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1051/0004-6361/202554110 external_id: arxiv: - '2502.07875' isi: - '001510826300017' file: - access_level: open_access checksum: 567fa02a9791d489355ec75d02bb1cb9 content_type: application/pdf creator: dernst date_created: 2025-06-30T08:44:24Z date_updated: 2025-06-30T08:44:24Z file_id: '19934' file_name: 2025_AstronomyAstrophysics_Furtak.pdf file_size: 1835865 relation: main_file success: 1 file_date_updated: 2025-06-30T08:44:24Z has_accepted_license: '1' intvolume: ' 698' isi: 1 language: - iso: eng month: '06' oa: 1 oa_version: Published Version publication: Astronomy & Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: Investigating photometric and spectroscopic variability in the multiply imaged little red dot A2744-QSO1 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 698 year: '2025' ...