---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21981'
abstract:
- lang: eng
  text: For Hamiltonian actions of semidirect products G = FxH, we study 2-cocycles
    arising from residual Hamiltonian actions of F on Hamiltonian reductions for H.
    The motivation comes from the study of Teichmüller spaces for surfaces with boundary,
    which carry Hamiltonian actions of the Virasoro algebra. In this paper, we give
    a general setup for the problem, and we suggest an easier way to obtain the Gelfand-Fuchs
    2-cocycles for Hamiltonian actions on Teichmüller spaces.
article_number: '105878'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Viacheslav
  full_name: Goncharov, Viacheslav
  id: 8a0e2993-7114-11f0-b60e-f50e633649d8
  last_name: Goncharov
citation:
  ama: Goncharov V. An easier way to compute 2-cocycles coming from a reduction for
    semidirect products. <i>Journal of Geometry and Physics</i>. 2026;227. doi:<a
    href="https://doi.org/10.1016/j.geomphys.2026.105878">10.1016/j.geomphys.2026.105878</a>
  apa: Goncharov, V. (2026). An easier way to compute 2-cocycles coming from a reduction
    for semidirect products. <i>Journal of Geometry and Physics</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.geomphys.2026.105878">https://doi.org/10.1016/j.geomphys.2026.105878</a>
  chicago: Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from
    a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>.
    Elsevier, 2026. <a href="https://doi.org/10.1016/j.geomphys.2026.105878">https://doi.org/10.1016/j.geomphys.2026.105878</a>.
  ieee: V. Goncharov, “An easier way to compute 2-cocycles coming from a reduction
    for semidirect products,” <i>Journal of Geometry and Physics</i>, vol. 227. Elsevier,
    2026.
  ista: Goncharov V. 2026. An easier way to compute 2-cocycles coming from a reduction
    for semidirect products. Journal of Geometry and Physics. 227, 105878.
  mla: Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction
    for Semidirect Products.” <i>Journal of Geometry and Physics</i>, vol. 227, 105878,
    Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.geomphys.2026.105878">10.1016/j.geomphys.2026.105878</a>.
  short: V. Goncharov, Journal of Geometry and Physics 227 (2026).
corr_author: '1'
date_created: 2026-06-10T07:29:13Z
date_published: 2026-05-21T00:00:00Z
date_updated: 2026-06-16T09:23:39Z
day: '21'
ddc:
- '000'
department:
- _id: GradSch
doi: 10.1016/j.geomphys.2026.105878
external_id:
  arxiv:
  - '2509.16169'
has_accepted_license: '1'
intvolume: '       227'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.geomphys.2026.105878
month: '05'
oa: 1
oa_version: Published Version
publication: Journal of Geometry and Physics
publication_identifier:
  eissn:
  - 1879-1662
  issn:
  - 0393-0440
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: An easier way to compute 2-cocycles coming from a reduction for semidirect
  products
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 227
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21472'
abstract:
- lang: eng
  text: We study the ground state energy of a gas of spin 1/2 fermions with repulsive
    short-range interactions. We derive an upper bound that agrees, at low density
    e, with the Huang–Yang conjecture. The latter captures the first three terms in
    an asymptotic low-density expansion, and in particular the Huang–Yang correction
    term of order e^7/3. Our trial state is constructed using an adaptation of the
    bosonic Bogoliubov theory to the Fermi system, where the correlation structure
    of fermionic particles is incorporated by quasi-bosonic Bogoliubov transformations.
    In the latter, it is important to consider a modified zero-energy scattering equation
    that takes into account the presence of the Fermi sea, in the spirit of the Bethe–Goldstone
    equation.
acknowledgement: "We thank the referees for valuable remarks. This work was partially
  funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)
  via the TRR 352 – Project-ID 470903074. PTN was partially supported by the European
  Research Council via the ERC Consolidator Grant RAMBAS – Project-Nr. 10104424.\r\nOpen
  access publishing facilitated by Università degli Studi di Milano, as part of the
  Wiley - CRUI-CARE agreement."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Emanuela L.
  full_name: Giacomelli, Emanuela L.
  last_name: Giacomelli
- first_name: Christian
  full_name: Hainzl, Christian
  last_name: Hainzl
- first_name: Phan Thành
  full_name: Nam, Phan Thành
  last_name: Nam
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: 'Giacomelli EL, Hainzl C, Nam PT, Seiringer R. The Huang–Yang formula for the
    low-density Fermi gas: Upper bound. <i>Communications on Pure and Applied Mathematics</i>.
    2026. doi:<a href="https://doi.org/10.1002/cpa.70040">10.1002/cpa.70040</a>'
  apa: 'Giacomelli, E. L., Hainzl, C., Nam, P. T., &#38; Seiringer, R. (2026). The
    Huang–Yang formula for the low-density Fermi gas: Upper bound. <i>Communications
    on Pure and Applied Mathematics</i>. Wiley. <a href="https://doi.org/10.1002/cpa.70040">https://doi.org/10.1002/cpa.70040</a>'
  chicago: 'Giacomelli, Emanuela L., Christian Hainzl, Phan Thành Nam, and Robert
    Seiringer. “The Huang–Yang Formula for the Low-Density Fermi Gas: Upper Bound.”
    <i>Communications on Pure and Applied Mathematics</i>. Wiley, 2026. <a href="https://doi.org/10.1002/cpa.70040">https://doi.org/10.1002/cpa.70040</a>.'
  ieee: 'E. L. Giacomelli, C. Hainzl, P. T. Nam, and R. Seiringer, “The Huang–Yang
    formula for the low-density Fermi gas: Upper bound,” <i>Communications on Pure
    and Applied Mathematics</i>. Wiley, 2026.'
  ista: 'Giacomelli EL, Hainzl C, Nam PT, Seiringer R. 2026. The Huang–Yang formula
    for the low-density Fermi gas: Upper bound. Communications on Pure and Applied
    Mathematics.'
  mla: 'Giacomelli, Emanuela L., et al. “The Huang–Yang Formula for the Low-Density
    Fermi Gas: Upper Bound.” <i>Communications on Pure and Applied Mathematics</i>,
    Wiley, 2026, doi:<a href="https://doi.org/10.1002/cpa.70040">10.1002/cpa.70040</a>.'
  short: E.L. Giacomelli, C. Hainzl, P.T. Nam, R. Seiringer, Communications on Pure
    and Applied Mathematics (2026).
date_created: 2026-03-22T23:04:33Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-06-18T08:30:39Z
day: '13'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1002/cpa.70040
external_id:
  arxiv:
  - '2409.17914'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/cpa.70040
month: '03'
oa: 1
oa_version: Published Version
publication: Communications on Pure and Applied Mathematics
publication_identifier:
  eissn:
  - 1097-0312
  issn:
  - 0010-3640
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Huang–Yang formula for the low-density Fermi gas: Upper bound'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21767'
abstract:
- lang: eng
  text: 'The involvement of non-scientific staff in discussions about animal welfare
    and scientific quality is essential for biomedical research progress. In this
    study, we developed a survey to collect the self-perception of animal care staff
    (ACS) and laboratory technicians about their involvement in scientific planning
    and conduct. Participants were contacted to complete an anonymous online questionnaire.
    We obtained 850 responses, mainly from Europe: 564 from ACS and 286 from laboratory
    technicians. Job satisfaction was assessed as positive by ACS and laboratory technicians
    despite the low frequency of culture of care activities and mental health meetings.
    Both groups expressed their desire to be trained in research planning and conduct;
    however, regular training was not reported. In addition, the inability to act
    on animal welfare concerns owing to experimental reasons was reported by both
    groups. Over half of the participants felt valued and appreciated by the lead
    scientists or animal facility manager; however, it is not clear how they are acknowledged,
    as their names on the authors list or in the manuscript acknowledgments are barely
    included. Our results indicated that involvement of ACS and laboratory technicians
    in planning and conducting studies would improve their understanding of how experiments
    are done, and therefore communication processes, work satisfaction, animal welfare,
    and scientific quality. Finally, we provided recommendations to improve the engagement
    of ACS and laboratory technicians in discussions about animal research planning
    and conduct.'
- lang: fre
  text: 'La participation de personnel non-scientifique aux discussions sur le bien-être
    animal et la qualité scientifique est essentielle aux progrès la recherche biomédicale.
    Dans cette étude, nous avons développé une enquête pour recueillir l''auto-perception
    du personnel chargé des soins prodigués aux animaux (PCSA) et des techniciens
    de laboratoire (TL) sur leur implication dans la planification et la conduite
    scientifiques. Les participants ont été contactés pour remplir un questionnaire
    anonyme en ligne. Nous avons obtenu 850 réponses, principalement en Europe : 564
    provenant de PCSA et 286 de TL. La satisfaction au travail a été évaluée comme
    positive par le PCSA et les TL malgré la faible fréquence d’activités sur la culture
    des soins et de réunions concernant la santé mentale. Bien que les deux groupes
    aient exprimé leur désir d''être formés à la planification et à la conduite de
    la recherche, aucune formation réelle régulière n''a été signalée. De plus, l''incapacité
    d''agir sur les préoccupations relatives au bien-être animal pour des raisons
    expérimentales a été signalée par les deux groupes. Plus de la moitié des participants
    se sont sentis valorisés et appréciés par les scientifiques principaux ou le gestionnaire
    de l’installation animale mais on ne sait pas clairement comment ils sont reconnus,
    car leurs noms sur la liste des auteurs ou dans les remerciements sont à peine
    inclus dans la documentation. Nos résultats ont indiqué que la participation du
    PCSA et des TL à la planification et à la conduite des études améliorerait leur
    compréhension de la façon dont les expériences sont effectuées et, par conséquent,
    les processus de communication, leur satisfaction au travail ainsi que le bien-être
    animal et la qualité scientifique. Enfin, nous avons formulé des recommandations
    pour améliorer la participation du PCSA et des TL aux discussions sur la planification
    et la conduite de la recherche animale.'
- lang: ger
  text: 'Die Einbeziehung von nichtwissenschaftlichem Personal in Diskussionen über
    Tierschutz und wissenschaftliche Qualität ist für Fortschritte in biomedizinischer
    Forschung von entscheidender Bedeutung. In dieser Studie haben wir eine Umfrage
    entwickelt, um die Selbsteinschätzung von Tierpflegern (ACS) und Labortechnikern
    (LT) hinsichtlich ihrer Beteiligung an der wissenschaftlichen Planung und Durchführung
    zu erfassen. Die Teilnehmer wurden gebeten, einen anonymen Online-Fragebogen auszufüllen.
    Wir erhielten 850 Rückmeldungen, hauptsächlich aus Europa: 564 von ACS und 286
    von LT. Die Arbeitszufriedenheit wurde von ACS und LT trotz der geringen Häufigkeit
    von Pflegeaktivitäten und Treffen zum Thema psychische Gesundheit als positiv
    bewertet. Beide Gruppen äußerten den Wunsch, in der Forschungsplanung und -durchführung
    geschult zu werden, doch regelmäßig stattfindende Schulungen wurden nicht berichtet.
    Außerdem wurde von beiden Gruppen vermeldet, dass sie aus versuchstechnischen
    Gründen nicht in der Lage waren, auf Tierschutzbedenken zu reagieren. Über die
    Hälfte der Teilnehmer fühlte sich von den leitenden Wissenschaftlern oder dem
    Leiter der Tierhaltungseinrichtung geschätzt und anerkannt; es ist jedoch unklar,
    inwiefern sie wirklich gewürdigt werden, da ihre Namen kaum in der Autorenliste
    oder in den Danksagungen des Manuskripts aufgeführt sind. Unsere Ergebnisse deuteten
    darauf hin, dass die Einbeziehung von ACS und LT in die Planung und Durchführung
    von Studien ihr Verständnis für die Durchführung von Experimenten verbessern würde
    – und damit auch Kommunikationsprozesse, Arbeitszufriedenheit, Tierwohl und wissenschaftliche
    Qualität. Abschließend gaben wir Empfehlungen zur Verbesserung der Einbeziehung
    von ACS und LT in Diskussionen über die Planung und Durchführung von Tierversuchen.'
- lang: spa
  text: 'La participación del personal no científico en los debates sobre el bienestar
    animal y la calidad científica es fundamental para el avance de la investigación
    biomédica. En este estudio, desarrollamos una encuesta para recoger la autopercepción
    del personal encargado del cuidado de los animales (ACS) y de los técnicos de
    laboratorio (LT) sobre su implicación en la planificación y la realización científicas.
    Se contactó con los participantes para que cumplimentaran un cuestionario anónimo
    en línea. Obtuvimos 850 respuestas, principalmente de Europa: 564 de ACS y 286
    de LT. La satisfacción laboral fue evaluada como positiva por ACS y técnicos de
    laboratorio a pesar de la baja frecuencia de actividades de cultura del cuidado
    y reuniones sobre bienestar mental. Ambos grupos expresaron su deseo de recibir
    formación en planificación y realización de investigaciones, sin embargo, no se
    informó sobre una formación regular. Asimismo, ambos grupos señalaron la incapacidad
    de actuar ante las preocupaciones sobre el bienestar animal por motivos experimentales.
    Más de la mitad de los participantes se sintieron valorados y apreciados por los
    científicos principales o el responsable de las instalaciones de animales; sin
    embargo, no está claro cómo se les reconoce, ya que apenas se incluyen sus nombres
    en la lista de autores o en los agradecimientos del manuscrito. Nuestros resultados
    indicaron que la participación de los ACS y los LT en la planificación y realización
    de los estudios mejoraría su comprensión de cómo se hacen los experimentos y,
    por tanto, los procesos de comunicación, la satisfacción laboral, el bienestar
    animal y la calidad científica. Finalmente, proporcionamos recomendaciones para
    mejorar el compromiso de la AEC y la LT en los debates sobre la planificación
    y la realización de investigaciones con animales.'
acknowledgement: "We deeply acknowledge all the animal care staff and laboratory technicians
  who participated in this study! We acknowledge Working Groups 1 and 4 from COST
  Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139,
  supported by COST (European Cooperation in Science and Technology) for their feedback
  and support. We also acknowledge Aoife Milford for her comments and contributions
  to the final draft of the manuscript.\r\nThis publication was based on work from
  the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”),
  CA21139, supported by COST (European Cooperation in Science and Technology)."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Fernando
  full_name: Gonzalez-Uarquin, Fernando
  last_name: Gonzalez-Uarquin
- first_name: Paulin
  full_name: Jirkof, Paulin
  last_name: Jirkof
- first_name: Bettina
  full_name: Bert, Bettina
  last_name: Bert
- first_name: Penny
  full_name: Hawkins, Penny
  last_name: Hawkins
- first_name: Ljupco
  full_name: Angelovski, Ljupco
  last_name: Angelovski
- first_name: Jan
  full_name: Baumgart, Jan
  last_name: Baumgart
- first_name: Nadine
  full_name: Baumgart, Nadine
  last_name: Baumgart
- first_name: Özge S.
  full_name: Cevik, Özge S.
  last_name: Cevik
- first_name: Nuno H.
  full_name: Franco, Nuno H.
  last_name: Franco
- first_name: Erdal
  full_name: Horata, Erdal
  last_name: Horata
- first_name: Rohish
  full_name: Kaura, Rohish
  last_name: Kaura
- first_name: Winfried
  full_name: Neuhaus, Winfried
  last_name: Neuhaus
- first_name: Brigida
  full_name: Riso, Brigida
  last_name: Riso
- first_name: Adrian J.
  full_name: Smith, Adrian J.
  last_name: Smith
- first_name: Athanassia
  full_name: Sotiropoulos, Athanassia
  last_name: Sotiropoulos
- first_name: Augusto
  full_name: Vitale, Augusto
  last_name: Vitale
- first_name: Sophie
  full_name: Schober, Sophie
  id: 80b0a0ef-4b9f-11ec-b119-8d9d94c4a1d8
  last_name: Schober
citation:
  ama: 'Gonzalez-Uarquin F, Jirkof P, Bert B, et al. Building bridges: Involvement
    of animal care staff and laboratory technicians in experimental planning and conduct
    of animal studies for better job satisfaction and science. <i>Laboratory Animals</i>.
    2026. doi:<a href="https://doi.org/10.1177/00236772251400976">10.1177/00236772251400976</a>'
  apa: 'Gonzalez-Uarquin, F., Jirkof, P., Bert, B., Hawkins, P., Angelovski, L., Baumgart,
    J., … Schober, S. (2026). Building bridges: Involvement of animal care staff and
    laboratory technicians in experimental planning and conduct of animal studies
    for better job satisfaction and science. <i>Laboratory Animals</i>. SAGE Publications.
    <a href="https://doi.org/10.1177/00236772251400976">https://doi.org/10.1177/00236772251400976</a>'
  chicago: 'Gonzalez-Uarquin, Fernando, Paulin Jirkof, Bettina Bert, Penny Hawkins,
    Ljupco Angelovski, Jan Baumgart, Nadine Baumgart, et al. “Building Bridges: Involvement
    of Animal Care Staff and Laboratory Technicians in Experimental Planning and Conduct
    of Animal Studies for Better Job Satisfaction and Science.” <i>Laboratory Animals</i>.
    SAGE Publications, 2026. <a href="https://doi.org/10.1177/00236772251400976">https://doi.org/10.1177/00236772251400976</a>.'
  ieee: 'F. Gonzalez-Uarquin <i>et al.</i>, “Building bridges: Involvement of animal
    care staff and laboratory technicians in experimental planning and conduct of
    animal studies for better job satisfaction and science,” <i>Laboratory Animals</i>.
    SAGE Publications, 2026.'
  ista: 'Gonzalez-Uarquin F, Jirkof P, Bert B, Hawkins P, Angelovski L, Baumgart J,
    Baumgart N, Cevik ÖS, Franco NH, Horata E, Kaura R, Neuhaus W, Riso B, Smith AJ,
    Sotiropoulos A, Vitale A, Schober S. 2026. Building bridges: Involvement of animal
    care staff and laboratory technicians in experimental planning and conduct of
    animal studies for better job satisfaction and science. Laboratory Animals.'
  mla: 'Gonzalez-Uarquin, Fernando, et al. “Building Bridges: Involvement of Animal
    Care Staff and Laboratory Technicians in Experimental Planning and Conduct of
    Animal Studies for Better Job Satisfaction and Science.” <i>Laboratory Animals</i>,
    SAGE Publications, 2026, doi:<a href="https://doi.org/10.1177/00236772251400976">10.1177/00236772251400976</a>.'
  short: F. Gonzalez-Uarquin, P. Jirkof, B. Bert, P. Hawkins, L. Angelovski, J. Baumgart,
    N. Baumgart, Ö.S. Cevik, N.H. Franco, E. Horata, R. Kaura, W. Neuhaus, B. Riso,
    A.J. Smith, A. Sotiropoulos, A. Vitale, S. Schober, Laboratory Animals (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-14T00:00:00Z
date_updated: 2026-06-18T08:33:36Z
day: '14'
ddc:
- '570'
department:
- _id: PreCl
doi: 10.1177/00236772251400976
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1177/00236772251400976
month: '04'
oa: 1
oa_version: Published Version
publication: Laboratory Animals
publication_identifier:
  eissn:
  - 1758-1117
  issn:
  - 0023-6772
publication_status: epub_ahead
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Building bridges: Involvement of animal care staff and laboratory technicians
  in experimental planning and conduct of animal studies for better job satisfaction
  and science'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21759'
abstract:
- lang: eng
  text: 'Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences
    that bind transcription factor (TF) proteins to up- or down-regulate target genes.
    Decades-long efforts yielded TF-DNA interaction models that predict how strongly
    an individual TF binds arbitrary DNA sequences and how individual binding events
    on the CRE combine to affect gene expression. These insights can be synthesized
    into a global, biophysically realistic, and quantitative genotype-phenotype (GP)
    map for gene regulation, a ‘holy grail’ for the application of evolutionary theory.
    A global map provides a rare opportunity to simulate the long-term evolution of
    regulatory sequences and pose several fundamental questions: How long does it
    take to evolve CREs de novo? How many non-trivial regulatory functions exist in
    sequence space? How connected are they? For which regulatory architecture is CRE
    evolution most rapid and evolvable? In this article, the second of a two-part
    series, we review the application of evolutionary concepts — epistasis, robustness,
    evolvability, tunability, plasticity, and bet-hedging — to the evolution of gene
    regulatory sequences. We then evaluate the potential for a unifying theory for
    the evolution of regulatory sequences and identify key open challenges.'
acknowledgement: "We thank Calin Guet and Santiago Herrera-Álvarez for essential contributions
  to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship,
  jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science
  and Technology Austria (ISTA). N.B. acknowledges funding from the ERC Advanced Grant
  101055327 “HaplotypeStructure”.\r\nThis study was also supported by the European
  Molecular Biology Laboratory (N.O.B., J.C.)."
article_number: '102472'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Elia
  full_name: Mascolo, Elia
  id: 776a6ed0-a053-11f0-8635-80b95e0e0d53
  last_name: Mascolo
  orcid: 0000-0003-2977-7844
- first_name: Reka E
  full_name: Körei, Reka E
  id: 50FDE43E-AA30-11E9-A72B-8A12E6697425
  last_name: Körei
- first_name: Noa O.
  full_name: Borst, Noa O.
  last_name: Borst
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Justin
  full_name: Crocker, Justin
  last_name: Crocker
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: 'Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. Long-term evolution
    of regulatory DNA sequences. Part 2: Theory and future challenges. <i>Current
    Opinion in Genetics and Development</i>. 2026;98. doi:<a href="https://doi.org/10.1016/j.gde.2026.102472">10.1016/j.gde.2026.102472</a>'
  apa: 'Mascolo, E., Körei, R. E., Borst, N. O., Barton, N. H., Crocker, J., &#38;
    Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 2: Theory
    and future challenges. <i>Current Opinion in Genetics and Development</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.gde.2026.102472">https://doi.org/10.1016/j.gde.2026.102472</a>'
  chicago: 'Mascolo, Elia, Reka E Körei, Noa O. Borst, Nicholas H Barton, Justin Crocker,
    and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 2: Theory
    and Future Challenges.” <i>Current Opinion in Genetics and Development</i>. Elsevier,
    2026. <a href="https://doi.org/10.1016/j.gde.2026.102472">https://doi.org/10.1016/j.gde.2026.102472</a>.'
  ieee: 'E. Mascolo, R. E. Körei, N. O. Borst, N. H. Barton, J. Crocker, and G. Tkačik,
    “Long-term evolution of regulatory DNA sequences. Part 2: Theory and future challenges,”
    <i>Current Opinion in Genetics and Development</i>, vol. 98. Elsevier, 2026.'
  ista: 'Mascolo E, Körei RE, Borst NO, Barton NH, Crocker J, Tkačik G. 2026. Long-term
    evolution of regulatory DNA sequences. Part 2: Theory and future challenges. Current
    Opinion in Genetics and Development. 98, 102472.'
  mla: 'Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part
    2: Theory and Future Challenges.” <i>Current Opinion in Genetics and Development</i>,
    vol. 98, 102472, Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.gde.2026.102472">10.1016/j.gde.2026.102472</a>.'
  short: E. Mascolo, R.E. Körei, N.O. Borst, N.H. Barton, J. Crocker, G. Tkačik, Current
    Opinion in Genetics and Development 98 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-06-18T08:34:09Z
day: '15'
ddc:
- '570'
department:
- _id: GaTk
- _id: NiBa
doi: 10.1016/j.gde.2026.102472
intvolume: '        98'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.gde.2026.102472
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
  grant_number: '101055327'
  name: Understanding the evolution of continuous genomes
publication: Current Opinion in Genetics and Development
publication_identifier:
  eissn:
  - 1879-0380
  issn:
  - 0959-437X
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Long-term evolution of regulatory DNA sequences. Part 2: Theory and future
  challenges'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21483'
abstract:
- lang: eng
  text: 'Embryogenesis in the model plant Arabidopsis thaliana provides a framework
    for understanding how cell polarity and patterning coordinate with hormonal signalling
    to establish the plant body plan. Following fertilisation, the zygote divides
    asymmetrically to generate apical and basal lineages, establishing the apical–basal
    axis that defines future shoot and root poles. Genetic and molecular analyses
    of classical mutants including gnom, monopteros (mp), bodenlos (bdl) and topless
    revealed that localised auxin biosynthesis, directional transport and downstream
    transcriptional responses are central to apical–basal axis establishment and organ
    initiation. The main components of this regulation are polarly localised PIN auxin
    transporters and downstream modules involving MONOPTEROS and WUSCHEL-RELATED HOMEOBOX
    transcription factors. Advances in microscopy have transformed the study of Arabidopsis
    embryogenesis: fluorescence-compatible clearing reagents and three-dimensional
    reconstructions now permit quantitative analyses of cell geometry, division orientation,
    and cytoskeletal dynamics. Live ovule imaging setups with confocal laser scanning
    and multiphoton microscopes enable real-time observation of embryo development,
    while laser-assisted cell ablation can be used to probe cell-to-cell communication
    and fate plasticity. Together, these methodological breakthroughs position Arabidopsis
    embryos as a prime model for dissecting the chemical and biophysical cues that
    shape plant development.'
acknowledgement: The authors would like to acknowledge the many colleagues whose valuable
  contributions to the field could not be included in this review due to space limitations
  and reference constraints. Open Access funding provided by Institute of Science
  and Technology Austria/KEMÖ.
article_number: nph.71072
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: David
  full_name: Babic, David
  id: db566d23-f6e0-11ea-865d-e6f270e968e7
  last_name: Babic
- first_name: Milan
  full_name: Zupunski, Milan
  id: f6a21fce-573e-11f0-a150-a8d96aee2539
  last_name: Zupunski
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Babic D, Zupunski M, Friml J. Imaging and genetic toolbox to study Arabidopsis
    embryogenesis. <i>New Phytologist</i>. 2026. doi:<a href="https://doi.org/10.1111/nph.71072">10.1111/nph.71072</a>
  apa: Babic, D., Zupunski, M., &#38; Friml, J. (2026). Imaging and genetic toolbox
    to study Arabidopsis embryogenesis. <i>New Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.71072">https://doi.org/10.1111/nph.71072</a>
  chicago: Babic, David, Milan Zupunski, and Jiří Friml. “Imaging and Genetic Toolbox
    to Study Arabidopsis Embryogenesis.” <i>New Phytologist</i>. Wiley, 2026. <a href="https://doi.org/10.1111/nph.71072">https://doi.org/10.1111/nph.71072</a>.
  ieee: D. Babic, M. Zupunski, and J. Friml, “Imaging and genetic toolbox to study
    Arabidopsis embryogenesis,” <i>New Phytologist</i>. Wiley, 2026.
  ista: Babic D, Zupunski M, Friml J. 2026. Imaging and genetic toolbox to study Arabidopsis
    embryogenesis. New Phytologist., nph. 71072.
  mla: Babic, David, et al. “Imaging and Genetic Toolbox to Study Arabidopsis Embryogenesis.”
    <i>New Phytologist</i>, nph. 71072, Wiley, 2026, doi:<a href="https://doi.org/10.1111/nph.71072">10.1111/nph.71072</a>.
  short: D. Babic, M. Zupunski, J. Friml, New Phytologist (2026).
corr_author: '1'
date_created: 2026-03-23T14:59:06Z
date_published: 2026-03-11T00:00:00Z
date_updated: 2026-06-18T08:31:45Z
day: '11'
ddc:
- '580'
department:
- _id: JiFr
- _id: GradSch
doi: 10.1111/nph.71072
external_id:
  pmid:
  - '41808651'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1111/nph.71072
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: New Phytologist
publication_identifier:
  eissn:
  - 1469-8137
  issn:
  - 0028-646X
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
status: public
title: Imaging and genetic toolbox to study Arabidopsis embryogenesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21484'
abstract:
- lang: eng
  text: An individual's phenotype reflects a complex interplay of the direct effects
    of their DNA, epigenetic modifications of their DNA induced by their parents,
    and indirect effects of their parents' DNA. Here, we derive how the genetic variance
    within a population is changed under the influence of indirect maternal, paternal
    and parent-of-origin effects under random mating. We also consider indirect effects
    of a sibling, in particular how the genetic variance is altered when looking at
    the phenotypic difference between two siblings. The calculations are then extended
    to include assortative mating (AM), which alters the variance by inducing increased
    homozygosity and correlations within and across loci. AM likely leads to covariance
    of parental genetic effects, a measure of the similarity of parents in the indirect
    effects they have on their children. We propose that this assortment for parental
    characteristics, where biological parents create similar environments for their
    children, can create shared parental effects across traits and the appearance
    of cross-trait AM. Our theory shows how the resemblance among relatives increases
    under both AM, indirect and parent-of-origin effects. When our model is used to
    predict correlations among relatives in human height, we find that explaining
    the patterns observed in real data requires both indirect genetic effects and
    assortative mating. The degree to which direct, indirect and epigenetic effects
    shape the phenotypic variance of complex traits remains an open question that
    requires large-scale family data to be resolved.
acknowledgement: We thank members of the Medical Genomics group at ISTA for their
  comments, which improved this manuscript. This work was funded by an SNSF Eccellenza
  Grant to MRR (PCEGP3-181181), and by core funding from the Institute of Science
  and Technology Austria.
article_number: iyag042
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Ilse
  full_name: Krätschmer, Ilse
  id: 30d4014e-7753-11eb-b44b-db6d61112e73
  last_name: Krätschmer
  orcid: 0000-0002-5636-9259
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
citation:
  ama: Krätschmer I, Robinson MR. A quantitative genetic model for indirect genetic
    effects and genomic imprinting under random and assortative mating. <i>Genetics</i>.
    2026. doi:<a href="https://doi.org/10.1093/genetics/iyag042">10.1093/genetics/iyag042</a>
  apa: Krätschmer, I., &#38; Robinson, M. R. (2026). A quantitative genetic model
    for indirect genetic effects and genomic imprinting under random and assortative
    mating. <i>Genetics</i>. Oxford University Press. <a href="https://doi.org/10.1093/genetics/iyag042">https://doi.org/10.1093/genetics/iyag042</a>
  chicago: Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic
    Model for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative
    Mating.” <i>Genetics</i>. Oxford University Press, 2026. <a href="https://doi.org/10.1093/genetics/iyag042">https://doi.org/10.1093/genetics/iyag042</a>.
  ieee: I. Krätschmer and M. R. Robinson, “A quantitative genetic model for indirect
    genetic effects and genomic imprinting under random and assortative mating,” <i>Genetics</i>.
    Oxford University Press, 2026.
  ista: Krätschmer I, Robinson MR. 2026. A quantitative genetic model for indirect
    genetic effects and genomic imprinting under random and assortative mating. Genetics.,
    iyag042.
  mla: Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic Model
    for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative
    Mating.” <i>Genetics</i>, iyag042, Oxford University Press, 2026, doi:<a href="https://doi.org/10.1093/genetics/iyag042">10.1093/genetics/iyag042</a>.
  short: I. Krätschmer, M.R. Robinson, Genetics (2026).
corr_author: '1'
date_created: 2026-03-23T15:02:54Z
date_published: 2026-02-12T00:00:00Z
date_updated: 2026-06-18T08:31:14Z
day: '12'
ddc:
- '570'
department:
- _id: MaRo
doi: 10.1093/genetics/iyag042
external_id:
  pmid:
  - '41677404'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/genetics/iyag042
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
  issn:
  - 1943-2631
publication_status: epub_ahead
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/medical-genomics-group/familyMC
status: public
title: A quantitative genetic model for indirect genetic effects and genomic imprinting
  under random and assortative mating
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21502'
abstract:
- lang: eng
  text: The mammalian brain stores glucose, the main circulating energy substrate,
    as glycogen. In rodents, the cerebellum contains relatively high glycogen levels,
    yet its cellular and subcellular distribution remains poorly defined. Using monoclonal
    antibodies against glycogen, we examined its distribution in the mouse cerebellar
    cortex. Glycogen was predominantly localized to Bergmann glia (BG) processes in
    the molecular layer and was also detected in Purkinje cells (PCs), the principal
    cerebellar neurons. To assess the functional significance of cerebellar glycogen,
    we analyzed behavior in mice lacking glycogen synthase 1 (Gys1) in BG or PCs using
    a floxed Gys1 line. Gys1 deficiency in either PCs or GFAP-positive cells reduced
    anxiety-like behavior, whereas combined deletion caused PC degeneration and ataxia.
    These findings reveal a critical role for glycogen metabolism in both astrocytes
    and neurons in cerebellar function.
acknowledgement: This work was supported by the Novo Nordisk Foundation (NNFOC0058058,
  H. Hirase), the Danmarks Frie Forskningsfond (0134-00107B and 5283-00069A, H.Hirase),
  the Lundbeck Foundation, Japan Society for the Promotion of Science Grants-in-Aid
  for Scientific Research (KAKENHI) program (22K06454/24H01221, A.K.; 23K27482, H.Hirai),
  the Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated
  Neurotechnologies for Disease Studies (Brain/MINDS) (JP21dm0207111, H. Hirai), AMED
  Brain/MINDS 2.0 (JP23wm0625001 and JP24wm0625103, H. Hirai), and grants from the
  Spanish Ministerio de Ciencia e Innovación (MCIU/FEDER/AEI) (PID2020-118699 GB-100,
  J.D.) and the Fundación Ramón Areces (J.D.). Sonam Akther has been supported by
  the RIKEN IPA fellowship. We are thankful to Dr. Yuki Oe for his support in the
  initial stage of this study and to Dan Xue for his help with the graphical abstract.
  We thank Dr. Pia Weikop for providing CTN research infrastructure. The authors declare
  no competing financial interests.
article_number: '115192'
article_processing_charge: Yes
article_type: original
author:
- first_name: Sonam
  full_name: Akther, Sonam
  last_name: Akther
- first_name: Ashley Bomin
  full_name: Lee, Ashley Bomin
  last_name: Lee
- first_name: Ayumu
  full_name: Konno, Ayumu
  last_name: Konno
- first_name: Antonis
  full_name: Asiminas, Antonis
  last_name: Asiminas
- first_name: Marta
  full_name: Vittani, Marta
  last_name: Vittani
- first_name: Tsuneko
  full_name: Mishima, Tsuneko
  last_name: Mishima
- first_name: Hirokazu
  full_name: Hirai, Hirokazu
  last_name: Hirai
- first_name: Claire Francesca
  full_name: Meehan, Claire Francesca
  last_name: Meehan
- first_name: Jordi
  full_name: Duran, Jordi
  last_name: Duran
- first_name: Joan
  full_name: Guinovart, Joan
  last_name: Guinovart
- first_name: Hitoshi
  full_name: Ashida, Hitoshi
  last_name: Ashida
- first_name: Tsuyoshi
  full_name: Morita, Tsuyoshi
  last_name: Morita
- first_name: Otto
  full_name: Baba, Otto
  last_name: Baba
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Maiken
  full_name: Nedergaard, Maiken
  last_name: Nedergaard
- first_name: Hajime
  full_name: Hirase, Hajime
  last_name: Hirase
citation:
  ama: Akther S, Lee AB, Konno A, et al. Distribution and functional significance
    of rodent cerebellar glycogen. <i>iScience</i>. 2026;29(4). doi:<a href="https://doi.org/10.1016/j.isci.2026.115192">10.1016/j.isci.2026.115192</a>
  apa: Akther, S., Lee, A. B., Konno, A., Asiminas, A., Vittani, M., Mishima, T.,
    … Hirase, H. (2026). Distribution and functional significance of rodent cerebellar
    glycogen. <i>IScience</i>. Elsevier. <a href="https://doi.org/10.1016/j.isci.2026.115192">https://doi.org/10.1016/j.isci.2026.115192</a>
  chicago: Akther, Sonam, Ashley Bomin Lee, Ayumu Konno, Antonis Asiminas, Marta Vittani,
    Tsuneko Mishima, Hirokazu Hirai, et al. “Distribution and Functional Significance
    of Rodent Cerebellar Glycogen.” <i>IScience</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.isci.2026.115192">https://doi.org/10.1016/j.isci.2026.115192</a>.
  ieee: S. Akther <i>et al.</i>, “Distribution and functional significance of rodent
    cerebellar glycogen,” <i>iScience</i>, vol. 29, no. 4. Elsevier, 2026.
  ista: Akther S, Lee AB, Konno A, Asiminas A, Vittani M, Mishima T, Hirai H, Meehan
    CF, Duran J, Guinovart J, Ashida H, Morita T, Baba O, Shigemoto R, Nedergaard
    M, Hirase H. 2026. Distribution and functional significance of rodent cerebellar
    glycogen. iScience. 29(4), 115192.
  mla: Akther, Sonam, et al. “Distribution and Functional Significance of Rodent Cerebellar
    Glycogen.” <i>IScience</i>, vol. 29, no. 4, 115192, Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.isci.2026.115192">10.1016/j.isci.2026.115192</a>.
  short: S. Akther, A.B. Lee, A. Konno, A. Asiminas, M. Vittani, T. Mishima, H. Hirai,
    C.F. Meehan, J. Duran, J. Guinovart, H. Ashida, T. Morita, O. Baba, R. Shigemoto,
    M. Nedergaard, H. Hirase, IScience 29 (2026).
date_created: 2026-03-29T22:07:07Z
date_published: 2026-03-17T00:00:00Z
date_updated: 2026-06-18T08:32:22Z
day: '17'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1016/j.isci.2026.115192
external_id:
  pmid:
  - '41890976'
intvolume: '        29'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.isci.2026.115192
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: iScience
publication_identifier:
  eissn:
  - 2589-0042
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distribution and functional significance of rodent cerebellar glycogen
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2026'
...
---
OA_place: publisher
OA_type: gold
_id: '21436'
abstract:
- lang: eng
  text: 'The cobalt-intercalated transition metal dichalcogenide CoxTaS2 hosts a rich
    landscape of magnetic phases that depend sensitively on x. While the stoichiometric
    compound with x = 1/3 exhibits a single magnetic transition, samples with x≤0.325
    display two transitions with an anomalous Hall effect (AHE) emerging in the lower
    temperature phase. Here, we resolve the spin structure in each phase by employing
    a suite of magneto-optical probes that include the discovery of anomalous magneto-birefringence:
    a spontaneous time-reversal sensitive rotation of the principal optic axes. A
    symmetry-based analysis identifies the AHE-active phase as an anisotropic (2+1)Q
    state, in which magnetic modulation at one wavevector (Q) differs in symmetry
    from that at the remaining two. The (2+1)Q state naturally exhibits scalar spin
    chirality as a mechanism for the AHE and expands the classification of multi-Q
    magnetic phases.'
acknowledgement: 'We thank Linda Ye and Yue Sun for helpful discussion. Experimental
  and theoretical work at LBNL and UC Berkeley was funded by the Quantum Materials
  (KC2202) program under the U.S. Department of Energy, Office of Science, Office
  of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract
  No. DE-AC02-05CH11231. V.S. and J.O. received support from the Gordon and Betty
  Moore Foundation’s EPiQS Initiative through Grant GBMF4537 to J.O. at UC Berkeley.
  J.K. received support from the National Science Foundation Graduate Research Fellowship
  Program under Grant No. 2146752. Any opinions, findings, and conclusions or recommendations
  expressed in this material are those of the author(s) and do not necessarily reflect
  the views of the National Science Foundation. During the preparation of this manuscript,
  we became aware of the following related work: refs. 56,57,58.'
article_number: '2507.12588'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Jonathon
  full_name: Kruppe, Jonathon
  last_name: Kruppe
- first_name: Josue
  full_name: Rodriguez, Josue
  last_name: Rodriguez
- first_name: Catherine
  full_name: Xu, Catherine
  last_name: Xu
- first_name: James
  full_name: Analytis, James
  last_name: Analytis
- first_name: Joseph
  full_name: Orenstein, Joseph
  last_name: Orenstein
- first_name: Veronika
  full_name: Sunko, Veronika
  id: 23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3
  last_name: Sunko
  orcid: 0000-0003-2724-3523
citation:
  ama: Kruppe J, Rodriguez J, Xu C, Analytis J, Orenstein J, Sunko V. Anisotropic
    multi-Q order in CoxTaS2. <i>npj Quantum Materials</i>. 2026. doi:<a href="https://doi.org/10.1038/s41535-026-00856-w">10.1038/s41535-026-00856-w</a>
  apa: Kruppe, J., Rodriguez, J., Xu, C., Analytis, J., Orenstein, J., &#38; Sunko,
    V. (2026). Anisotropic multi-Q order in CoxTaS2. <i>Npj Quantum Materials</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41535-026-00856-w">https://doi.org/10.1038/s41535-026-00856-w</a>
  chicago: Kruppe, Jonathon, Josue Rodriguez, Catherine Xu, James Analytis, Joseph
    Orenstein, and Veronika Sunko. “Anisotropic Multi-Q Order in CoxTaS2.” <i>Npj
    Quantum Materials</i>. Springer Nature, 2026. <a href="https://doi.org/10.1038/s41535-026-00856-w">https://doi.org/10.1038/s41535-026-00856-w</a>.
  ieee: J. Kruppe, J. Rodriguez, C. Xu, J. Analytis, J. Orenstein, and V. Sunko, “Anisotropic
    multi-Q order in CoxTaS2,” <i>npj Quantum Materials</i>. Springer Nature, 2026.
  ista: Kruppe J, Rodriguez J, Xu C, Analytis J, Orenstein J, Sunko V. 2026. Anisotropic
    multi-Q order in CoxTaS2. npj Quantum Materials., 2507.12588.
  mla: Kruppe, Jonathon, et al. “Anisotropic Multi-Q Order in CoxTaS2.” <i>Npj Quantum
    Materials</i>, 2507.12588, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41535-026-00856-w">10.1038/s41535-026-00856-w</a>.
  short: J. Kruppe, J. Rodriguez, C. Xu, J. Analytis, J. Orenstein, V. Sunko, Npj
    Quantum Materials (2026).
corr_author: '1'
date_created: 2026-03-11T10:39:55Z
date_published: 2026-04-09T00:00:00Z
date_updated: 2026-06-18T08:32:52Z
day: '09'
ddc:
- '530'
department:
- _id: VeSu
doi: 10.1038/s41535-026-00856-w
external_id:
  arxiv:
  - '2507.12588'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41535-026-00856-w
month: '04'
oa: 1
oa_version: Published Version
publication: npj Quantum Materials
publication_identifier:
  eissn:
  - 2397-4648
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Anisotropic multi-Q order in CoxTaS2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21986'
abstract:
- lang: eng
  text: Over the past two decades, molecular electronics has made significant progress
    toward discovering nanoscale analogues of conventional electronic components,
    largely enabled by the development of the scanning tunneling microscope-based
    break-junction (STM-BJ) technique. The STM-BJ technique enables precise and highly
    reproducible measurement of a molecule’s electronic transport properties, making
    it a powerful technique to explore physiochemical and electrochemical phenomena
    that are otherwise difficult to access. It has gained substantial popularity in
    the past 20 years, with experiments becoming increasingly diverse and sophisticated.
    Despite the wealth of literature, an accessible, practical guide to performing
    STM-BJ experiments and interpreting the data is largely absent. This tutorial
    includes a brief background into the development of STM-BJ measurements, followed
    by detailed explanations of instrumentation, data collection, statistical analysis,
    variations on standard experiments, and some troubleshooting methods. It is aimed
    at researchers looking to begin or improve STM-BJ studies in their laboratories,
    graduate students and postdoctoral researchers learning the technique, and readers
    seeking to critically evaluate the growing body of STM-BJ literature.
acknowledgement: We thank Michael Inkpen, Timothy Su, Masha Kamenetska, and Wanzhuo
  Shi for comments and Jyotisman Hazarika for data collection. This work was supported
  in part by the National Science Foundation (NSF-DMR 2241180) and by the Institute
  of Science and Technology Austria.
article_processing_charge: Yes
article_type: original
author:
- first_name: Emma
  full_name: York, Emma
  id: 08dde91e-8e0a-11f0-9d7d-9e8d80864f16
  last_name: York
- first_name: Latha
  full_name: Venkataraman, Latha
  id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
  last_name: Venkataraman
  orcid: 0000-0002-6957-6089
citation:
  ama: York E, Venkataraman L. Scanning tunneling microscope-based break-junction
    technique - A tutorial. <i>ACS Physical Chemistry Au</i>. 2026;6(3):408-424. doi:<a
    href="https://doi.org/10.1021/acsphyschemau.6c00026">10.1021/acsphyschemau.6c00026</a>
  apa: York, E., &#38; Venkataraman, L. (2026). Scanning tunneling microscope-based
    break-junction technique - A tutorial. <i>ACS Physical Chemistry Au</i>. American
    Chemical Society. <a href="https://doi.org/10.1021/acsphyschemau.6c00026">https://doi.org/10.1021/acsphyschemau.6c00026</a>
  chicago: York, Emma, and Latha Venkataraman. “Scanning Tunneling Microscope-Based
    Break-Junction Technique - A Tutorial.” <i>ACS Physical Chemistry Au</i>. American
    Chemical Society, 2026. <a href="https://doi.org/10.1021/acsphyschemau.6c00026">https://doi.org/10.1021/acsphyschemau.6c00026</a>.
  ieee: E. York and L. Venkataraman, “Scanning tunneling microscope-based break-junction
    technique - A tutorial,” <i>ACS Physical Chemistry Au</i>, vol. 6, no. 3. American
    Chemical Society, pp. 408–424, 2026.
  ista: York E, Venkataraman L. 2026. Scanning tunneling microscope-based break-junction
    technique - A tutorial. ACS Physical Chemistry Au. 6(3), 408–424.
  mla: York, Emma, and Latha Venkataraman. “Scanning Tunneling Microscope-Based Break-Junction
    Technique - A Tutorial.” <i>ACS Physical Chemistry Au</i>, vol. 6, no. 3, American
    Chemical Society, 2026, pp. 408–24, doi:<a href="https://doi.org/10.1021/acsphyschemau.6c00026">10.1021/acsphyschemau.6c00026</a>.
  short: E. York, L. Venkataraman, ACS Physical Chemistry Au 6 (2026) 408–424.
corr_author: '1'
date_created: 2026-06-10T07:38:41Z
date_published: 2026-05-04T00:00:00Z
date_updated: 2026-06-19T06:35:58Z
day: '04'
ddc:
- '540'
department:
- _id: LaVe
doi: 10.1021/acsphyschemau.6c00026
external_id:
  pmid:
  - '42221941'
file:
- access_level: open_access
  checksum: 1dc16bdfb1c1cd3acde802f4350cb42a
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-19T06:31:16Z
  date_updated: 2026-06-19T06:31:16Z
  file_id: '22020'
  file_name: 2026_ACSPhysChem_York.pdf
  file_size: 11251172
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  success: 1
file_date_updated: 2026-06-19T06:31:16Z
has_accepted_license: '1'
intvolume: '         6'
issue: '3'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 408-424
pmid: 1
publication: ACS Physical Chemistry Au
publication_identifier:
  eissn:
  - 2694-2445
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scanning tunneling microscope-based break-junction technique - A tutorial
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '21987'
abstract:
- lang: eng
  text: 'We introduce JODIE, a genetic joint modeling approach that estimates how
    DNA loci influence human traits by partitioning genetic effects into four components:
    direct effects (from a child’s alleles), indirect maternal and paternal effects
    (from parents’ alleles), and parent-of-origin (PofO) effects (dependent on parental
    transmission of alleles), while uniquely accounting for assortative mating. We
    analyze 30,000 child-mother-father trios from the Estonian Biobank and the Norwegian
    Mother, Father, and Child Cohort, focusing on height, body mass index, and childhood
    educational test scores. We find direct effects to be the largest contributor
    to trait variation, but combined, indirect parental and PofO effects are similarly
    substantial. We support our results by within-family genome-wide association testing
    and identify 276 independently associated DNA regions with a complex interplay
    between direct, indirect, and PofO effects. By joint modeling, we show that direct,
    indirect, and PofO effects collectively shape human phenotypic variation across
    loci genome-wide.'
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank Zoltan Kutalik, Peter Visscher, and members of the Robinson
  group at ISTA for their comments, which improved this manuscript. This work was
  funded by an SNSF Eccellenza Grant to M.R.R. (PCEGP3-181181) and by core funding
  from the Institute of Science and Technology Austria.\r\nThe Norwegian Mother, Father,
  and Child Cohort Study is supported by the Norwegian Ministry of Health and Care
  Services and the Ministry of Education and Research. We are grateful to all the
  participating families in Norway who take part in this on-going cohort study. We
  thank the Norwegian Institute of Public Health (NIPH) for generating high-quality
  genomic data. The research is part of the HARVEST collaboration, supported by the
  Research Council of Norway (#229624). We also thank the NORMENT Center for providing
  genotype data, funded by the Research Council of Norway (#223273), South East Norway
  Health Authorities, and Stiftelsen Kristian Gerhard Jebsen, and in collaboration
  with deCODE Genetics. We further thank the Center for Diabetes Research, the University
  of Bergen for providing genotype data funded by the ERC AdG project SELECTionPREDISPOSED,
  Stiftelsen Kristian Gerhard Jebsen, Trond Mohn Foundation, the Research Council
  of Norway, the Novo Nordisk Foundation, the University of Bergen, and the Western
  Norway Health Authorities. The MoBa work was performed on the TSD (Tjeneste for
  Sensitive Data) facilities, owned by the University of Oslo, operated and developed
  by the TSD service group at the University of Oslo, IT Department (USIT, tsd-drift@usit.uio.no).
  E.Y. is supported by the European Union (grant numbers 101045526 and 101073237)
  and the Research Council of Norway (grant numbers 336078, 288083, and 331640).\r\nWe
  would like to acknowledge the participants and investigators of the Generation Scotland
  Cohort study. Generation Scotland received core support from the Chief Scientist
  Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish
  Funding Council (HR03006). Genotyping and methylation typing of the GS:SFHS samples
  was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research
  Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK
  and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and
  Depression Longitudinally” [STRADL] ref. 104036/Z/14/Z).\r\nWe would like to thank
  and acknowledge the participants and investigators of the Estonian Biobank (EstBB)
  study. The research was conducted using the Estonian Center of Genomics/Roadmap
  II funded by the Estonian Research Council (project number TT17).\r\nNorwegian analyses
  were performed on resources provided by Sigma2 - the National Infrastructure for
  High-Performance Computing and Data Storage in Norway. Estonian Data analysis was
  carried out in the High-Performance Computing Center cloud provided by University
  of Tartu. Analysis of the Generation Scotland data and the summary statistics obtained
  from the other analyses was conducted at IST Austria and is supported by the Scientific
  Service Units (SSU) of IST Austria through resources provided by Scientific Computing
  (SciComp)."
article_number: '101277'
article_processing_charge: Yes
article_type: original
author:
- first_name: Ilse
  full_name: Krätschmer, Ilse
  id: 30d4014e-7753-11eb-b44b-db6d61112e73
  last_name: Krätschmer
  orcid: 0000-0002-5636-9259
- first_name: Laura
  full_name: Hegemann, Laura
  last_name: Hegemann
- first_name: Robin J.
  full_name: Hofmeister, Robin J.
  last_name: Hofmeister
- first_name: Elizabeth C.
  full_name: Corfield, Elizabeth C.
  last_name: Corfield
- first_name: Mahdi
  full_name: Mahmoudi, Mahdi
  last_name: Mahmoudi
- first_name: Olivier
  full_name: Delaneau, Olivier
  last_name: Delaneau
- first_name: Ole A.
  full_name: Andreassen, Ole A.
  last_name: Andreassen
- first_name: Archie
  full_name: Campbell, Archie
  last_name: Campbell
- first_name: Caroline
  full_name: Hayward, Caroline
  last_name: Hayward
- first_name: Riccardo E.
  full_name: Marioni, Riccardo E.
  last_name: Marioni
- first_name: Eivind
  full_name: Ystrom, Eivind
  last_name: Ystrom
- first_name: Alexandra
  full_name: Havdahl, Alexandra
  last_name: Havdahl
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
citation:
  ama: Krätschmer I, Hegemann L, Hofmeister RJ, et al. Separating direct, indirect,
    and parent-of-origin genetic effects in the human population. <i>Cell Genomics</i>.
    doi:<a href="https://doi.org/10.1016/j.xgen.2026.101277">10.1016/j.xgen.2026.101277</a>
  apa: Krätschmer, I., Hegemann, L., Hofmeister, R. J., Corfield, E. C., Mahmoudi,
    M., Delaneau, O., … Robinson, M. R. (n.d.). Separating direct, indirect, and parent-of-origin
    genetic effects in the human population. <i>Cell Genomics</i>. Elsevier. <a href="https://doi.org/10.1016/j.xgen.2026.101277">https://doi.org/10.1016/j.xgen.2026.101277</a>
  chicago: Krätschmer, Ilse, Laura Hegemann, Robin J. Hofmeister, Elizabeth C. Corfield,
    Mahdi Mahmoudi, Olivier Delaneau, Ole A. Andreassen, et al. “Separating Direct,
    Indirect, and Parent-of-Origin Genetic Effects in the Human Population.” <i>Cell
    Genomics</i>. Elsevier, n.d. <a href="https://doi.org/10.1016/j.xgen.2026.101277">https://doi.org/10.1016/j.xgen.2026.101277</a>.
  ieee: I. Krätschmer <i>et al.</i>, “Separating direct, indirect, and parent-of-origin
    genetic effects in the human population,” <i>Cell Genomics</i>. Elsevier.
  ista: Krätschmer I, Hegemann L, Hofmeister RJ, Corfield EC, Mahmoudi M, Delaneau
    O, Andreassen OA, Campbell A, Hayward C, Marioni RE, Ystrom E, Havdahl A, Robinson
    MR. Separating direct, indirect, and parent-of-origin genetic effects in the human
    population. Cell Genomics., 101277.
  mla: Krätschmer, Ilse, et al. “Separating Direct, Indirect, and Parent-of-Origin
    Genetic Effects in the Human Population.” <i>Cell Genomics</i>, 101277, Elsevier,
    doi:<a href="https://doi.org/10.1016/j.xgen.2026.101277">10.1016/j.xgen.2026.101277</a>.
  short: I. Krätschmer, L. Hegemann, R.J. Hofmeister, E.C. Corfield, M. Mahmoudi,
    O. Delaneau, O.A. Andreassen, A. Campbell, C. Hayward, R.E. Marioni, E. Ystrom,
    A. Havdahl, M.R. Robinson, Cell Genomics (n.d.).
corr_author: '1'
date_created: 2026-06-10T07:39:08Z
date_published: 2026-06-09T00:00:00Z
date_updated: 2026-06-19T07:00:47Z
day: '09'
department:
- _id: MaRo
doi: 10.1016/j.xgen.2026.101277
external_id:
  pmid:
  - '40909755'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.xgen.2026.101277
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 9B8D11D6-BA93-11EA-9121-9846C619BF3A
  grant_number: PCEGP3_181181
  name: Improving estimation and prediction of common complex disease risk
publication: Cell Genomics
publication_identifier:
  eissn:
  - 2666-979X
publication_status: inpress
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Separating direct, indirect, and parent-of-origin genetic effects in the human
  population
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21994'
abstract:
- lang: eng
  text: Adaptive plant development is orchestrated, among others, by directional,
    intercellular transport of the phytohormone auxin. Self-organizing development,
    such as flexible vasculature formation, depends on so-called auxin canalization,
    manifested by the gradual formation of auxin transport channels through feedback
    between auxin signalling and transport. Herein, we identify MAKR6 as an important,
    novel component in this feedback. MAKR6 expression accumulates strongly in vascular
    cells and is tightly regulated by auxin via the Aux/IAA-ARF-WRKY23 transcriptional
    network. MAKR6 is required for auxin canalization-dependent processes, including
    leaf venation, vasculature regeneration, and de novo auxin channel formation from
    local auxin sources. Mechanistically, MAKR6 interacts with the PIN1 auxin transporter,
    modulating its trafficking and polarization. MAKR6 also associates with and integrates
    two key receptor-like kinase complexes involved in canalization, TMK1/4 and the
    CAMEL-CANAR. Together, our study establishes MAKR6 as a multifaceted regulator
    that couples transcriptional auxin signalling to PIN1 repolarization and coordinates
    multiple RLK-mediated signalling pathways during canalization. This provides mechanistic
    insights into auxin canalization and exemplifies a framework for exploring similar
    regulatory nodes in other developmental contexts.
acknowledgement: 'We would like to thank Dr. Yvon Jaillais (ENS, Lyon) for sharing
  MAKR2 materials. This research was supported by the Scientific Service Units (SSU)
  of ISTA through resources provided by the Imaging & Optics Facility (IOF) and the
  Lab Support Facility (LSF). The research in the Friml group leading to these results
  was funded by the European Research Council (ERC): 101142681 CYNIPS; and the Austrian
  Science Fund (FWF): I 6123-B and P 37051-B. Ewa Mazur was supported by the National
  Science Centre (NCN), Poland, under the OPUS call in the WEAVE programme: 2021/43/I/NZ1/01835.'
article_processing_charge: No
author:
- first_name: Zengxiang
  full_name: Ge, Zengxiang
  id: f43371a3-09ff-11eb-8013-bd0c6a2f6de8
  last_name: Ge
  orcid: 0000-0001-9381-3577
- first_name: Lilla
  full_name: Koczka, Lilla
  last_name: Koczka
- first_name: Ewa
  full_name: Mazur, Ewa
  last_name: Mazur
- first_name: Gergely
  full_name: Molnar, Gergely
  id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
  last_name: Molnar
- first_name: Dmitrii
  full_name: Vladimirtsev, Dmitrii
  id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
  last_name: Vladimirtsev
- first_name: Nada
  full_name: Kassem, Nada
  last_name: Kassem
- first_name: Sara
  full_name: Ait Ikene, Sara
  id: 6a0bb896-6bad-11f1-9bef-906e9eb76034
  last_name: Ait Ikene
- first_name: Lukas
  full_name: Fiedler, Lukas
  id: 7c417475-8972-11ed-ae7b-8b674ca26986
  last_name: Fiedler
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Ge Z, Koczka L, Mazur E, et al. MAKR6 integrates TMK and CAMEL/CANAR signalling
    for auxin canalization in Arabidopsis. <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2025.10.07.680881">10.1101/2025.10.07.680881</a>
  apa: Ge, Z., Koczka, L., Mazur, E., Molnar, G., Vladimirtsev, D., Kassem, N., …
    Friml, J. (n.d.). MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization
    in Arabidopsis. <i>bioRxiv</i>. <a href="https://doi.org/10.1101/2025.10.07.680881">https://doi.org/10.1101/2025.10.07.680881</a>
  chicago: Ge, Zengxiang, Lilla Koczka, Ewa Mazur, Gergely Molnar, Dmitrii Vladimirtsev,
    Nada Kassem, Sara Ait Ikene, Lukas Fiedler, and Jiří Friml. “MAKR6 Integrates
    TMK and CAMEL/CANAR Signalling for Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>,
    n.d. <a href="https://doi.org/10.1101/2025.10.07.680881">https://doi.org/10.1101/2025.10.07.680881</a>.
  ieee: Z. Ge <i>et al.</i>, “MAKR6 integrates TMK and CAMEL/CANAR signalling for
    auxin canalization in Arabidopsis,” <i>bioRxiv</i>. .
  ista: Ge Z, Koczka L, Mazur E, Molnar G, Vladimirtsev D, Kassem N, Ait Ikene S,
    Fiedler L, Friml J. MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin
    canalization in Arabidopsis. bioRxiv, <a href="https://doi.org/10.1101/2025.10.07.680881">10.1101/2025.10.07.680881</a>.
  mla: Ge, Zengxiang, et al. “MAKR6 Integrates TMK and CAMEL/CANAR Signalling for
    Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>, doi:<a href="https://doi.org/10.1101/2025.10.07.680881">10.1101/2025.10.07.680881</a>.
  short: Z. Ge, L. Koczka, E. Mazur, G. Molnar, D. Vladimirtsev, N. Kassem, S. Ait
    Ikene, L. Fiedler, J. Friml, BioRxiv (n.d.).
corr_author: '1'
date_created: 2026-06-13T16:57:07Z
date_published: 2026-05-30T00:00:00Z
date_updated: 2026-06-19T07:14:01Z
day: '30'
ddc:
- '580'
department:
- _id: GradSch
- _id: JiFr
doi: 10.1101/2025.10.07.680881
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.10.07.680881
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
  grant_number: '101142681'
  name: Cyclic nucleotides as second messengers in plants
- _id: bd76d395-d553-11ed-ba76-f678c14f9033
  grant_number: I06123
  name: Peptide receptors for auxin canalization in Arabidopsis
- _id: 7bcece63-9f16-11ee-852c-ae94e099eeb6
  grant_number: P37051
  name: Guanylate cyclase activity of TIR1/AFBs auxin receptors
publication: bioRxiv
publication_status: submitted
scopus_import: '1'
status: public
title: MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21998'
abstract:
- lang: eng
  text: Little Red Dots (LRDs), among the most enigmatic high-redshift discoveries
    by JWST, are commonly believed to be powered by accreting supermassive black holes.
    Here, we explore the possibility that these sources are globular clusters in formation,
    with rest-frame UV arising from a very young stellar population and rest-frame
    optical from a short-lived supermassive (>104 M⊙) star. The spectral profiles
    of LRDs are broadly consistent with this scenario, though the observed temperatures
    and bolometric luminosities favor emission reprocessed by optically thick continuum-driven
    winds not fully captured by current models. The LRD z ∼ 5−7 UV luminosity function
    naturally evolves, under standard evolutionary and mass-loss prescriptions, into
    a present-day mass function with a turnover at log10(M*/M⊙) = 5.3 and an exponential
    cutoff at high masses, consistent with local globular cluster populations. We
    estimate the total present-day number density of LRDs formed across all redshifts
    to be ≈0.3 Mpc−3, similar within uncertainties to local globular clusters. The
    observed LRD redshift range matches the age distribution of metal-poor globular
    clusters, without current LRD counterparts to the metal-rich population. If LRDs
    are globular clusters in formation, we predict chemical abundance patterns characteristic
    of multiple stellar populations, including enhanced He and N, and potential Na–O
    and Al–Mg anticorrelations. These results offer a local perspective to explore
    this surprisingly abundant population of distant sources, and a potential new
    window into extreme stellar astrophysics in the early Universe.
acknowledgement: "We thank the referees for detailed and highly constructive reports
  that significantly improved the scope and breadth of the manuscript. J.C. thanks
  Hollis Akins, Volker Bromm, Rui Chaves-Marques, Steve Finkelstein, Karl Gebhardt,
  Keith Hawkins, Harley Katz, Stellar Offner, Daniel Schaerer, Grace Telford, and
  Jorick Vink for conversations that improved the Letter. A.d.G. acknowledges support
  from a Clay Fellowship awarded by the Smithsonian Astrophysical Observatory. M.B.K.
  acknowledges support from NSF grants AST-2108962 and AST-2408247; NASA grant 80NSSC22K0827;
  HST-GO-16686, HST-AR-17028, JWST-GO-03788, and JWST-AR-06278 from the Space Telescope
  Science Institute, which is operated by AURA, Inc., under NASA contract NAS5-26555;
  and from the Samuel T. and Fern Yanagisawa Regents Professorship in Astronomy at
  UT Austin. A.A.C.S. acknowledges support by the Deutsche Forschungsgemeinschaft
  (DFG, German Research Foundation) in the form of an Emmy Noether Research Group—Project-ID
  445674056 (SA4064/1-1, PI Sander). A.A.C.S. further acknowledges support from the
  Deutsches Zentrum für Luft und Raumfahrt (DLR) grant grants 50 OR 2509 (PI: A.A.C.
  Sander) and 50 OR 2306 (PI: V. Ramachandran/A.A.C. Sander) as well as from the Federal
  Ministry of Research, Technology, and Space (BMFTR) and the Baden-Württemberg Ministry
  of Science as part of the Excellence Strategy of the German Federal and State Governments.
  This project was cofunded by the European Union (Project 101183150—OCEANS).\r\n\r\nThis
  work is based in part on observations made with the NASA/ESA/CSA James Webb Space
  Telescope. The data were obtained from the Mikulski Archive for Space Telescopes
  at the Space Telescope Science Institute, which is operated by the Association of
  Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for
  JWST. These observations are associated with programs 1180, 1181, 1208, 1212, 1213,
  1215, 1286, 1345, 1433, 2198, 2561, 2750, 2767, 4106, 4233, 5105, 5224, 6368, and
  6585."
article_number: L4
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: John
  full_name: Chisholm, John
  last_name: Chisholm
- first_name: Danielle A.
  full_name: Berg, Danielle A.
  last_name: Berg
- first_name: Michael
  full_name: Boylan-Kolchin, Michael
  last_name: Boylan-Kolchin
- first_name: Anna
  full_name: De Graaff, Anna
  last_name: De Graaff
- first_name: Lukas J.
  full_name: Furtak, Lukas J.
  last_name: Furtak
- first_name: Vasily
  full_name: Kokorev, Vasily
  last_name: Kokorev
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Julian B.
  full_name: Muñoz, Julian B.
  last_name: Muñoz
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Andreas A.C.
  full_name: Sander, Andreas A.C.
  last_name: Sander
citation:
  ama: Chisholm J, Berg DA, Boylan-Kolchin M, et al. Little Red Dots as globular clusters
    in formation. <i>The Astrophysical Journal Letters</i>. 2026;1004(1). doi:<a href="https://doi.org/10.3847/2041-8213/ae6dae">10.3847/2041-8213/ae6dae</a>
  apa: Chisholm, J., Berg, D. A., Boylan-Kolchin, M., De Graaff, A., Furtak, L. J.,
    Kokorev, V., … Sander, A. A. C. (2026). Little Red Dots as globular clusters in
    formation. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href="https://doi.org/10.3847/2041-8213/ae6dae">https://doi.org/10.3847/2041-8213/ae6dae</a>
  chicago: Chisholm, John, Danielle A. Berg, Michael Boylan-Kolchin, Anna De Graaff,
    Lukas J. Furtak, Vasily Kokorev, Jorryt J Matthee, Julian B. Muñoz, Rohan P. Naidu,
    and Andreas A.C. Sander. “Little Red Dots as Globular Clusters in Formation.”
    <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2026. <a href="https://doi.org/10.3847/2041-8213/ae6dae">https://doi.org/10.3847/2041-8213/ae6dae</a>.
  ieee: J. Chisholm <i>et al.</i>, “Little Red Dots as globular clusters in formation,”
    <i>The Astrophysical Journal Letters</i>, vol. 1004, no. 1. IOP Publishing, 2026.
  ista: Chisholm J, Berg DA, Boylan-Kolchin M, De Graaff A, Furtak LJ, Kokorev V,
    Matthee JJ, Muñoz JB, Naidu RP, Sander AAC. 2026. Little Red Dots as globular
    clusters in formation. The Astrophysical Journal Letters. 1004(1), L4.
  mla: Chisholm, John, et al. “Little Red Dots as Globular Clusters in Formation.”
    <i>The Astrophysical Journal Letters</i>, vol. 1004, no. 1, L4, IOP Publishing,
    2026, doi:<a href="https://doi.org/10.3847/2041-8213/ae6dae">10.3847/2041-8213/ae6dae</a>.
  short: J. Chisholm, D.A. Berg, M. Boylan-Kolchin, A. De Graaff, L.J. Furtak, V.
    Kokorev, J.J. Matthee, J.B. Muñoz, R.P. Naidu, A.A.C. Sander, The Astrophysical
    Journal Letters 1004 (2026).
date_created: 2026-06-14T22:01:42Z
date_published: 2026-06-10T00:00:00Z
date_updated: 2026-06-19T09:50:33Z
day: '10'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/2041-8213/ae6dae
external_id:
  arxiv:
  - '2602.15935'
file:
- access_level: open_access
  checksum: 66949af6e620c8ef37de42688829a3e3
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-19T09:45:21Z
  date_updated: 2026-06-19T09:45:21Z
  file_id: '22098'
  file_name: 2026_AstrophysicalJourLetters_Chisholm.pdf
  file_size: 919919
  relation: main_file
  success: 1
file_date_updated: 2026-06-19T09:45:21Z
has_accepted_license: '1'
intvolume: '      1004'
issue: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal Letters
publication_identifier:
  eissn:
  - 2041-8213
  issn:
  - 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Little Red Dots as globular clusters in formation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1004
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21997'
abstract:
- lang: eng
  text: 'The massive binary common envelope (CE) phase plays a pivotal role in the
    formation of close black hole (BH)/neutron star binaries, yet significant uncertainties
    remain in our understanding of this process. In this study, we aim to constrain
    the massive binary CE phase by systematically reconstructing three observed BH
    X-ray binaries (BHXBs): GRO J1655-40, SAX J1819.3-2525, and 4U 1543-47. Through
    comprehensive binary evolution simulations and parametric supernova modeling,
    we establish lower limits for the CE efficiency parameters under different energy
    considerations within the standard energy formalism. Specifically, we derive minimum
    values for three cases: α0.5U and αU, representing CE efficiencies with half and
    all of the internal energy contributing to the envelope ejection, respectively,
    and αH, accounting for the envelope’s enthalpy. Our analysis reveals that the
    self-consistent formation of these three BHXBs requires CE efficiency parameters
    satisfying α0.5U ≳ 6.7, αU ≳ 4.2, and αH ≳ 1.7. Notably, we find no viable solutions
    with CE efficiency values below unity, even when considering the most extreme
    scenarios, in which the envelope binding energy is significantly reduced through
    enthalpy inclusion. Our results strongly imply that either additional energy sources
    are required or the formalism itself must be revised. Furthermore, we quantitatively
    assess the impact of BH natal kicks on our results. A key finding is that 4U 1543-47’s
    formation requires substantial natal kicks (≳50 km s−1), as lower kick velocities
    are incompatible with isolated binary evolution.'
acknowledgement: We deeply thank the referee for a very careful reading and constructive
  comments that have led to the improvement of the manuscript. The authors are grateful
  to Poshak Gandhi for his valuable suggestions and feedback on this work. This work
  is supported by the Natural Science Foundation of China (grant Nos. 12125303, 12525304,
  12288102, 12473034, 12103028, 12333008, 12422305, 12090040/3, 12273105, 11703081,
  11422324, 12073070, and 12173081), the CAS Project for Young Scientists in Basic
  Research (YSBR-148), the Strategic Priority Research Program of the Chinese Academy
  of Sciences (grant Nos. XDB1160303, XDB1160201, and XDB1160000), the National Key
  R&D Program of China (grant Nos. 2021YFA1600403 and 2021YFA1600400), the Key Research
  Program of Frontier Sciences of CAS (No. ZDBS-LY-7005), the “CAS Light of West China”,
  the Yunnan Revitalization Talent Support Program-Science & Technology Champion Project
  (No. 202305AB350003) and Young Talent Project, the International Centre of Supernovae
  (ICESUN), Yunnan Key Laboratory of Supernova Research (Nos. 202302AN360001 and 202201BC070003),
  Yunnan Fundamental Research Projects (No. 202401AT070139), and the Natural Science
  Foundation of Henan Province (No. 242300420944). X.C. acknowledges the New Cornerstone
  Science Foundation through the XPLORER PRIZE. The authors gratefully acknowledge
  the “PHOENIX Supercomputing Platform” jointly operated by the Binary Population
  Synthesis Group and the Stellar Astrophysics Group at Yunnan Observatories, Chinese
  Academy of Sciences.
article_number: '31'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Zhenwei
  full_name: Li, Zhenwei
  last_name: Li
- first_name: Dandan
  full_name: Wei, Dandan
  id: 5dd129bd-0601-11ef-b325-833284687b76
  last_name: Wei
- first_name: Shi
  full_name: Jia, Shi
  last_name: Jia
- first_name: Hailiang
  full_name: Chen, Hailiang
  last_name: Chen
- first_name: Hongwei
  full_name: Ge, Hongwei
  last_name: Ge
- first_name: Zhuo
  full_name: Chen, Zhuo
  last_name: Chen
- first_name: Yangyang
  full_name: Zhang, Yangyang
  last_name: Zhang
- first_name: Xuefei
  full_name: Chen, Xuefei
  last_name: Chen
- first_name: Zhanwen
  full_name: Han, Zhanwen
  last_name: Han
citation:
  ama: 'Li Z, Wei D, Jia S, et al. A path to constraints on common envelope ejection
    in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray
    binaries. <i>The Astrophysical Journal</i>. 2026;1004(1). doi:<a href="https://doi.org/10.3847/1538-4357/ae66fd">10.3847/1538-4357/ae66fd</a>'
  apa: 'Li, Z., Wei, D., Jia, S., Chen, H., Ge, H., Chen, Z., … Han, Z. (2026). A
    path to constraints on common envelope ejection in massive binaries: Full evolutionary
    reconstruction of three Black Hole X-ray binaries. <i>The Astrophysical Journal</i>.
    IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/ae66fd">https://doi.org/10.3847/1538-4357/ae66fd</a>'
  chicago: 'Li, Zhenwei, Dandan Wei, Shi Jia, Hailiang Chen, Hongwei Ge, Zhuo Chen,
    Yangyang Zhang, Xuefei Chen, and Zhanwen Han. “A Path to Constraints on Common
    Envelope Ejection in Massive Binaries: Full Evolutionary Reconstruction of Three
    Black Hole X-Ray Binaries.” <i>The Astrophysical Journal</i>. IOP Publishing,
    2026. <a href="https://doi.org/10.3847/1538-4357/ae66fd">https://doi.org/10.3847/1538-4357/ae66fd</a>.'
  ieee: 'Z. Li <i>et al.</i>, “A path to constraints on common envelope ejection in
    massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries,”
    <i>The Astrophysical Journal</i>, vol. 1004, no. 1. IOP Publishing, 2026.'
  ista: 'Li Z, Wei D, Jia S, Chen H, Ge H, Chen Z, Zhang Y, Chen X, Han Z. 2026. A
    path to constraints on common envelope ejection in massive binaries: Full evolutionary
    reconstruction of three Black Hole X-ray binaries. The Astrophysical Journal.
    1004(1), 31.'
  mla: 'Li, Zhenwei, et al. “A Path to Constraints on Common Envelope Ejection in
    Massive Binaries: Full Evolutionary Reconstruction of Three Black Hole X-Ray Binaries.”
    <i>The Astrophysical Journal</i>, vol. 1004, no. 1, 31, IOP Publishing, 2026,
    doi:<a href="https://doi.org/10.3847/1538-4357/ae66fd">10.3847/1538-4357/ae66fd</a>.'
  short: Z. Li, D. Wei, S. Jia, H. Chen, H. Ge, Z. Chen, Y. Zhang, X. Chen, Z. Han,
    The Astrophysical Journal 1004 (2026).
date_created: 2026-06-14T22:01:42Z
date_published: 2026-06-10T00:00:00Z
date_updated: 2026-06-19T09:58:52Z
day: '10'
ddc:
- '520'
department:
- _id: YlGo
doi: 10.3847/1538-4357/ae66fd
external_id:
  arxiv:
  - '2604.10440'
file:
- access_level: open_access
  checksum: bb76fbb51f8d2834cb79f19e7932e3bd
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-19T09:56:29Z
  date_updated: 2026-06-19T09:56:29Z
  file_id: '22099'
  file_name: 2026_AstrophysicalJour_Li.pdf
  file_size: 3386217
  relation: main_file
  success: 1
file_date_updated: 2026-06-19T09:56:29Z
has_accepted_license: '1'
intvolume: '      1004'
issue: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A path to constraints on common envelope ejection in massive binaries: Full
  evolutionary reconstruction of three Black Hole X-ray binaries'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1004
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14278'
abstract:
- lang: eng
  text: 'The Birkhoff conjecture says that the boundary of a strictly convex integrable
    billiard table is necessarily an ellipse. In this article, we consider a stronger
    notion of integrability, namely, integrability close to the boundary, and prove
    a local version of this conjecture: a small perturbation of almost every ellipse
    that preserves integrability near the boundary, is itself an ellipse. We apply
    this result to study local spectral uniqueness of ellipses using the connection
    between the wave trace of the Laplacian and the dynamics near the boundary and
    establish local uniqueness for almost all of them.'
acknowledgement: 'The author acknowledges the partial support of the European Research
  Council Grant #885707. He also thanks Vadim Kaloshin for proposing the idea of the
  project and greatly aiding the implementation. The author is also grateful to Hamid
  Hezari, Amir Vig, Steve Zelditch, Comlan E. Koudjinan, Corentin Fierobe, Ngo Nhok
  Tkhai Shon and Roman Sarapin for useful discussions. The author also acknowledges
  partial support of ISTern summer program. The project started in the summer of 2021,
  when the author was an intern at ISTA. Open access funding provided by Institute
  of Science and Technology (IST Austria).'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Illya
  full_name: Koval, Illya
  id: 2eed1f3b-896a-11ed-bdf8-93c7c4bf159e
  last_name: Koval
citation:
  ama: Koval I. Local strong Birkhoff conjecture and local spectral rigidity of almost
    every ellipse. <i>Inventiones Mathematicae</i>. 2025. doi:<a href="https://doi.org/10.1007/s00222-025-01397-y">10.1007/s00222-025-01397-y</a>
  apa: Koval, I. (2025). Local strong Birkhoff conjecture and local spectral rigidity
    of almost every ellipse. <i>Inventiones Mathematicae</i>. Springer Nature. <a
    href="https://doi.org/10.1007/s00222-025-01397-y">https://doi.org/10.1007/s00222-025-01397-y</a>
  chicago: Koval, Illya. “Local Strong Birkhoff Conjecture and Local Spectral Rigidity
    of Almost Every Ellipse.” <i>Inventiones Mathematicae</i>. Springer Nature, 2025.
    <a href="https://doi.org/10.1007/s00222-025-01397-y">https://doi.org/10.1007/s00222-025-01397-y</a>.
  ieee: I. Koval, “Local strong Birkhoff conjecture and local spectral rigidity of
    almost every ellipse,” <i>Inventiones Mathematicae</i>. Springer Nature, 2025.
  ista: Koval I. 2025. Local strong Birkhoff conjecture and local spectral rigidity
    of almost every ellipse. Inventiones Mathematicae.
  mla: Koval, Illya. “Local Strong Birkhoff Conjecture and Local Spectral Rigidity
    of Almost Every Ellipse.” <i>Inventiones Mathematicae</i>, Springer Nature, 2025,
    doi:<a href="https://doi.org/10.1007/s00222-025-01397-y">10.1007/s00222-025-01397-y</a>.
  short: I. Koval, Inventiones Mathematicae (2025).
corr_author: '1'
date_created: 2023-09-06T08:35:43Z
date_published: 2025-12-11T00:00:00Z
date_updated: 2025-12-29T11:37:48Z
day: '11'
ddc:
- '510'
department:
- _id: GradSch
- _id: VaKa
doi: 10.1007/s00222-025-01397-y
ec_funded: 1
external_id:
  arxiv:
  - '2111.12171'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s00222-025-01397-y
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A
  call_identifier: H2020
  grant_number: '885707'
  name: Spectral rigidity and integrability for billiards and geodesic flows
publication: Inventiones Mathematicae
publication_identifier:
  eissn:
  - 1432-1297
  issn:
  - 0020-9910
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Local strong Birkhoff conjecture and local spectral rigidity of almost every
  ellipse
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '14647'
abstract:
- lang: eng
  text: "In the developing vertebrate central nervous system, neurons and glia typically
    arise\r\nsequentially from common progenitors. Here, we report that the transcription
    factor Forkhead\r\nBox G1 (Foxg1) regulates gliogenesis in the mouse neocortex
    via distinct cell-autonomous roles in progenitors and postmitotic neurons that
    regulate different aspects of the gliogenic FGF signalling pathway. We demonstrate
    that loss of Foxg1 in cortical progenitors at neurogenic stages causes premature
    astrogliogenesis. We identify a novel FOXG1 target, the pro-gliogenic FGF pathway
    component Fgfr3, which is suppressed by FOXG1 cell-autonomously to maintain neurogenesis.
    Furthermore, FOXG1 can also suppress premature astrogliogenesis triggered by the
    augmentation of FGF signalling. We identify a second novel function of FOXG1 in
    regulating the expression of gliogenic cues in newborn neocortical upper-layer
    neurons. Loss of FOXG1 in postmitotic neurons non-autonomously enhances gliogenesis
    in the progenitors via FGF signalling. These results fit well with the model that
    newborn neurons secrete cues that trigger progenitors to produce the next wave
    of cell types, astrocytes. If FGF signalling is attenuated in Foxg1 null progenitors,
    they progress to oligodendrocyte production. Therefore, loss of FOXG1 transitions
    the progenitor to a gliogenic state, producing either astrocytes or oligodendrocytes
    depending on FGF signalling levels. Our results uncover how FOXG1 integrates extrinsic
    signalling via the FGF pathway to regulate the sequential generation of neurons,
    astrocytes, and oligodendrocytes in the cerebral cortex. "
acknowledgement: "We thank the animal house staff of the Tata Institute of Fundamental
  Research, Mumbai (TIFR), for their excellent support; Gordon Fishell (Harvard Medical
  School, USA), and Goichi Miyoshi (Gunma University, Japan) for the Foxg1 floxed
  mouse line; Hiroshi Kawasaki (Kanazawa University, Japan) for the plasmids pCAG-FGF8
  and pCAG-sFgfr3c; Soo Kyung Lee (University at Buffalo, The State University of
  New York, USA) for the Foxg1lox/lox genotyping primers and protocol. We thank Deepak
  Modi and Vainav Patel (National Institute for Research in Reproductive and Child
  Health, NIRRCH, Mumbai, India) for the use of the NIRRCH FACS Facility, and the
  staff of the NIRRCH and TIFR FACS facilities for their assistance. We thank Denis
  Jabaudon (University of Geneva, Switzerland) for his critical comments on the manuscript
  and members of the Jabaudon lab for helpful discussions. This work was funded by
  the Department of Atomic Energy (DAE), Govt. of India (Project Identification no.
  RTI4003,\r\nDAE OM no. 1303/2/2019/R&D-II/DAE/2079). "
article_number: '101851'
article_processing_charge: Yes
article_type: original
author:
- first_name: Mahima
  full_name: Bose, Mahima
  last_name: Bose
- first_name: Varun
  full_name: Suresh, Varun
  last_name: Suresh
- first_name: Urvi
  full_name: Mishra, Urvi
  last_name: Mishra
- first_name: Ishita
  full_name: Talwar, Ishita
  last_name: Talwar
- first_name: Anuradha
  full_name: Yadav, Anuradha
  last_name: Yadav
- first_name: Shiona
  full_name: Biswas, Shiona
  last_name: Biswas
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Shubha
  full_name: Tole, Shubha
  last_name: Tole
citation:
  ama: Bose M, Suresh V, Mishra U, et al. Dual role of FOXG1 in regulating gliogenesis
    in the developing neocortex via the FGF signalling pathway. <i>eLife</i>. 2025;13.
    doi:<a href="https://doi.org/10.7554/elife.101851.3">10.7554/elife.101851.3</a>
  apa: Bose, M., Suresh, V., Mishra, U., Talwar, I., Yadav, A., Biswas, S., … Tole,
    S. (2025). Dual role of FOXG1 in regulating gliogenesis in the developing neocortex
    via the FGF signalling pathway. <i>ELife</i>. eLife Sciences Publications. <a
    href="https://doi.org/10.7554/elife.101851.3">https://doi.org/10.7554/elife.101851.3</a>
  chicago: Bose, Mahima, Varun Suresh, Urvi Mishra, Ishita Talwar, Anuradha Yadav,
    Shiona Biswas, Simon Hippenmeyer, and Shubha Tole. “Dual Role of FOXG1 in Regulating
    Gliogenesis in the Developing Neocortex via the FGF Signalling Pathway.” <i>ELife</i>.
    eLife Sciences Publications, 2025. <a href="https://doi.org/10.7554/elife.101851.3">https://doi.org/10.7554/elife.101851.3</a>.
  ieee: M. Bose <i>et al.</i>, “Dual role of FOXG1 in regulating gliogenesis in the
    developing neocortex via the FGF signalling pathway,” <i>eLife</i>, vol. 13. eLife
    Sciences Publications, 2025.
  ista: Bose M, Suresh V, Mishra U, Talwar I, Yadav A, Biswas S, Hippenmeyer S, Tole
    S. 2025. Dual role of FOXG1 in regulating gliogenesis in the developing neocortex
    via the FGF signalling pathway. eLife. 13, 101851.
  mla: Bose, Mahima, et al. “Dual Role of FOXG1 in Regulating Gliogenesis in the Developing
    Neocortex via the FGF Signalling Pathway.” <i>ELife</i>, vol. 13, 101851, eLife
    Sciences Publications, 2025, doi:<a href="https://doi.org/10.7554/elife.101851.3">10.7554/elife.101851.3</a>.
  short: M. Bose, V. Suresh, U. Mishra, I. Talwar, A. Yadav, S. Biswas, S. Hippenmeyer,
    S. Tole, ELife 13 (2025).
date_created: 2023-12-06T13:07:01Z
date_published: 2025-03-14T00:00:00Z
date_updated: 2025-05-14T11:41:52Z
day: '14'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.7554/elife.101851.3
external_id:
  pmid:
  - '40085500'
file:
- access_level: open_access
  checksum: 64a6a6f86e24b21fe72c7a7fd6056fed
  content_type: application/pdf
  creator: dernst
  date_created: 2025-04-03T11:19:26Z
  date_updated: 2025-04-03T11:19:26Z
  file_id: '19467'
  file_name: 2025_eLife_Bose.pdf
  file_size: 17462771
  relation: main_file
  success: 1
file_date_updated: 2025-04-03T11:19:26Z
has_accepted_license: '1'
intvolume: '        13'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
  eissn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via
  the FGF signalling pathway
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '18074'
abstract:
- lang: eng
  text: The Aharonov–Casher theorem is a result on the number of the so-called zero
    modes of a system described by the magnetic Pauli operator in R2. In this paper
    we address the same question for the Dirac operator on a flat two-dimensional
    manifold with boundary and Atiyah–Patodi–Singer boundary condition. More concretely
    we are interested in the plane and a disc with a finite number of circular holes
    cut out. We consider a smooth compactly supported magnetic field on the manifold
    and an arbitrary magnetic field inside the holes.
acknowledgement: "First and foremost I am grateful to Jan Philip Solovej for fruitful
  meetings during (and after) my PhD programme, when this work was done. Further I
  would like to thank Joshua Hunt, Anna Sisak, Jakub Löwit, Błażej Ruba, Volodymir
  Riabov, Lukas Schimmer and Georgios Koutentakis for valuable discussions. Many thanks
  belong to Rafael Benguria for hosting my visit, during which some of the work has
  been done. I am also grateful to Marina Prokhorova who first initiated the discussion
  of this project topic and to Annemarie Luger for her valuable comments during my
  PhD defence and in particular pointing out the qualitative difference in our two
  main results. I would like to acknowledge support for research on this paper from
  VILLUM FONDEN through the QMATH Centre of Excellence grant. nr. 10059. This project
  also received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement No 101034413. I am grateful
  to the two reviewers for reading carefully my manuscript and pointing out several
  issues contributing thus significantly to the readability and clarity of this paper.\r\nOpen
  access funding provided by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Marie
  full_name: Fialova, Marie
  id: e9c9844d-9e21-11ec-b482-f96fc09f7c4d
  last_name: Fialova
citation:
  ama: Fialova M. Aharonov–Casher theorems for Dirac operators on manifolds with boundary
    and APS boundary condition. <i>Annales Henri Poincare</i>. 2025;26:2859-2900.
    doi:<a href="https://doi.org/10.1007/s00023-024-01482-7">10.1007/s00023-024-01482-7</a>
  apa: Fialova, M. (2025). Aharonov–Casher theorems for Dirac operators on manifolds
    with boundary and APS boundary condition. <i>Annales Henri Poincare</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00023-024-01482-7">https://doi.org/10.1007/s00023-024-01482-7</a>
  chicago: Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds
    with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>. Springer
    Nature, 2025. <a href="https://doi.org/10.1007/s00023-024-01482-7">https://doi.org/10.1007/s00023-024-01482-7</a>.
  ieee: M. Fialova, “Aharonov–Casher theorems for Dirac operators on manifolds with
    boundary and APS boundary condition,” <i>Annales Henri Poincare</i>, vol. 26.
    Springer Nature, pp. 2859–2900, 2025.
  ista: Fialova M. 2025. Aharonov–Casher theorems for Dirac operators on manifolds
    with boundary and APS boundary condition. Annales Henri Poincare. 26, 2859–2900.
  mla: Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds
    with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>, vol.
    26, Springer Nature, 2025, pp. 2859–900, doi:<a href="https://doi.org/10.1007/s00023-024-01482-7">10.1007/s00023-024-01482-7</a>.
  short: M. Fialova, Annales Henri Poincare 26 (2025) 2859–2900.
corr_author: '1'
date_created: 2024-09-15T22:01:42Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-09-30T10:22:14Z
day: '01'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s00023-024-01482-7
ec_funded: 1
external_id:
  arxiv:
  - '2304.13373'
  isi:
  - '001304370000001'
file:
- access_level: open_access
  checksum: d8d2d6dbce293c9ee6eaa9262e597147
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-05T11:24:25Z
  date_updated: 2025-08-05T11:24:25Z
  file_id: '20124'
  file_name: 2025_AnnalesHenriPoincare_Fialova.pdf
  file_size: 728124
  relation: main_file
  success: 1
file_date_updated: 2025-08-05T11:24:25Z
has_accepted_license: '1'
intvolume: '        26'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 2859-2900
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Aharonov–Casher theorems for Dirac operators on manifolds with boundary and
  APS boundary condition
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 26
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18154'
abstract:
- lang: eng
  text: 'In 1976, Deligne and Lusztig realized the representation theory of finite
    groups of Lie type inside étale cohomology of certain algebraic varieties. Recently,
    a p-adic version of this theory started to emerge: there are p-adic Deligne–Lusztig
    spaces, whose cohomology encodes representation theoretic information for p-adic
    groups – for instance, it partially realizes the local Langlands correspondence
    with characteristic zero coefficients. However, the parallel case of coefficients
    of positive characteristic  ℓ≠p has not been inspected so far. The purpose of
    this article is to initiate such an inspection. In particular, we relate cohomology
    of certain p-adic Deligne–Lusztig spaces to Vignéras''s modular local Langlands
    correspondence for GLn.'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Jakub
  full_name: Löwit, Jakub
  id: e3b80ae2-eb8e-11eb-b029-9aef4a9108a0
  last_name: Löwit
citation:
  ama: Löwit J. On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn.
    <i>Journal of Algebra</i>. 2025;663(2):81-118. doi:<a href="https://doi.org/10.1016/j.jalgebra.2024.08.033">10.1016/j.jalgebra.2024.08.033</a>
  apa: Löwit, J. (2025). On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties
    for GLn. <i>Journal of Algebra</i>. Elsevier. <a href="https://doi.org/10.1016/j.jalgebra.2024.08.033">https://doi.org/10.1016/j.jalgebra.2024.08.033</a>
  chicago: Löwit, Jakub. “On modulo ℓ Cohomology of P-Adic Deligne–Lusztig Varieties
    for GLn.” <i>Journal of Algebra</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.jalgebra.2024.08.033">https://doi.org/10.1016/j.jalgebra.2024.08.033</a>.
  ieee: J. Löwit, “On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for
    GLn,” <i>Journal of Algebra</i>, vol. 663, no. 2. Elsevier, pp. 81–118, 2025.
  ista: Löwit J. 2025. On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties
    for GLn. Journal of Algebra. 663(2), 81–118.
  mla: Löwit, Jakub. “On modulo ℓ Cohomology of P-Adic Deligne–Lusztig Varieties for
    GLn.” <i>Journal of Algebra</i>, vol. 663, no. 2, Elsevier, 2025, pp. 81–118,
    doi:<a href="https://doi.org/10.1016/j.jalgebra.2024.08.033">10.1016/j.jalgebra.2024.08.033</a>.
  short: J. Löwit, Journal of Algebra 663 (2025) 81–118.
corr_author: '1'
date_created: 2024-09-29T22:01:37Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2025-02-27T12:32:40Z
day: '01'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1016/j.jalgebra.2024.08.033
external_id:
  arxiv:
  - '2404.11176'
  isi:
  - '001325207800001'
file:
- access_level: open_access
  checksum: eb240e93c178e48429ad918c9058f1fe
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  creator: dernst
  date_created: 2025-01-13T08:57:57Z
  date_updated: 2025-01-13T08:57:57Z
  file_id: '18830'
  file_name: 2024_JourAlgebra_Loewit.pdf
  file_size: 731175
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file_date_updated: 2025-01-13T08:57:57Z
has_accepted_license: '1'
intvolume: '       663'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 81-118
publication: Journal of Algebra
publication_identifier:
  eissn:
  - 1090-266X
  issn:
  - 0021-8693
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 663
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18157'
abstract:
- lang: eng
  text: "Interest in sliding block puzzles dates back to the 15-puzzle, seemingly
    invented by Noyes Chapman in 1874 (see [23] for an account of the fascinating
    history of the puzzle). The game consists of fifteen movable square blocks numbered
    \r\n and arranged within a \r\n square box, leaving one empty space (see Figure
    1). The task at hand is to start from a given configuration of the numbered blocks
    and reach the desired target configuration, where the only allowed move is to
    slide a numbered block into an adjacent empty space. This task seemed to be unpredictably
    either very easy to accomplish, or completely impossible, and the puzzle turned
    into a worldwide sensation in the spring of 1880. A particularly challenging instance,
    known as the 13-15-14 puzzle, consisted of initial and target configurations that
    differed by a single swap (historically this swap involved the blocks labeled
    14 and 15). The craze of this puzzle was such that it consistently made newspaper
    headlines in 1880, with an article in the New York Times lamenting that it was
    “threatening our free institutions” [23, p. 9]. Various prizes were offered for
    anyone who could solve this challenge, beginning with a $25 set of teeth and culminating
    with Sam Loyd’s famous $1,000 cash prize."
acknowledgement: Open access funding provided by Copenhagen University.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Florestan R
  full_name: Brunck, Florestan R
  id: 6ab6e556-f394-11eb-9cf6-9dfb78f00d8d
  last_name: Brunck
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
citation:
  ama: 'Brunck FR, Kwan MA. Books, Hallways, and social butterflies: A note on sliding
    block puzzles. <i>Mathematical Intelligencer</i>. 2025;47:52-65. doi:<a href="https://doi.org/10.1007/s00283-024-10358-x">10.1007/s00283-024-10358-x</a>'
  apa: 'Brunck, F. R., &#38; Kwan, M. A. (2025). Books, Hallways, and social butterflies:
    A note on sliding block puzzles. <i>Mathematical Intelligencer</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00283-024-10358-x">https://doi.org/10.1007/s00283-024-10358-x</a>'
  chicago: 'Brunck, Florestan R, and Matthew Alan Kwan. “Books, Hallways, and Social
    Butterflies: A Note on Sliding Block Puzzles.” <i>Mathematical Intelligencer</i>.
    Springer Nature, 2025. <a href="https://doi.org/10.1007/s00283-024-10358-x">https://doi.org/10.1007/s00283-024-10358-x</a>.'
  ieee: 'F. R. Brunck and M. A. Kwan, “Books, Hallways, and social butterflies: A
    note on sliding block puzzles,” <i>Mathematical Intelligencer</i>, vol. 47. Springer
    Nature, pp. 52–65, 2025.'
  ista: 'Brunck FR, Kwan MA. 2025. Books, Hallways, and social butterflies: A note
    on sliding block puzzles. Mathematical Intelligencer. 47, 52–65.'
  mla: 'Brunck, Florestan R., and Matthew Alan Kwan. “Books, Hallways, and Social
    Butterflies: A Note on Sliding Block Puzzles.” <i>Mathematical Intelligencer</i>,
    vol. 47, Springer Nature, 2025, pp. 52–65, doi:<a href="https://doi.org/10.1007/s00283-024-10358-x">10.1007/s00283-024-10358-x</a>.'
  short: F.R. Brunck, M.A. Kwan, Mathematical Intelligencer 47 (2025) 52–65.
date_created: 2024-09-29T22:01:38Z
date_published: 2025-03-01T00:00:00Z
date_updated: 2025-05-19T14:00:09Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
- _id: MaKw
doi: 10.1007/s00283-024-10358-x
external_id:
  arxiv:
  - '2303.09459'
  isi:
  - '001318056000001'
file:
- access_level: open_access
  checksum: c932ebe45c460d4a73f5b2dcca643db1
  content_type: application/pdf
  creator: dernst
  date_created: 2025-04-08T11:17:45Z
  date_updated: 2025-04-08T11:17:45Z
  file_id: '19530'
  file_name: 2025_MathIntelligencer_Brunck.pdf
  file_size: 1760643
  relation: main_file
  success: 1
file_date_updated: 2025-04-08T11:17:45Z
has_accepted_license: '1'
intvolume: '        47'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 52-65
publication: Mathematical Intelligencer
publication_identifier:
  issn:
  - 0343-6993
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Books, Hallways, and social butterflies: A note on sliding block puzzles'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 47
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18169'
abstract:
- lang: eng
  text: "As the complexity and criticality of software increase every year, so does
    the importance of runtime monitoring. Third-party and best-effort monitoring are
    especially valuable, yet under-explored areas of runtime monitoring. In this context,
    third-party monitoring means monitoring with a limited knowledge of the monitored
    software (as it has been developed by a third party). Best-effort monitoring keeps
    pace with the monitored software at the cost of possibly imprecise verdicts when
    keeping up with the monitored software would not be feasible. Most existing monitoring
    frameworks do not support the combination of third-party and best-effort monitoring
    because they either require the full access to the monitored code or the ability
    to process all observable events, or both.\r\nWe present a middleware framework,
    Vamos, for the runtime monitoring of software. Vamos is explicitly designed to
    support third-party and best-effort scenarios. The design goals of Vamos are (i)
    efficiency (tracing events with low overhead), (ii) flexibility (the ability to
    monitor a variety of different event channels, and to connect to a wide range
    of monitors), and (iii) ease-of-use. To achieve its goals, Vamos combines aspects
    of event broker and event recognition systems with aspects of stream processing
    systems.\r\nWe implemented a prototype toolchain for Vamos and conducted a set
    of experiments demonstrating the usability of the scheme. The results indicate
    that Vamos enables writing useful yet efficient monitors, and simplifies key aspects
    of setting up a monitoring system from scratch."
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. The
  authors would like to thank the STTT reviewers for their valuable feedback and suggestions.
article_number: '103212'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Marek
  full_name: Chalupa, Marek
  id: 87e34708-d6c6-11ec-9f5b-9391e7be2463
  last_name: Chalupa
- first_name: Fabian
  full_name: Mühlböck, Fabian
  id: 6395C5F6-89DF-11E9-9C97-6BDFE5697425
  last_name: Mühlböck
  orcid: 0000-0003-1548-0177
- first_name: Stefanie
  full_name: Muroya Lei, Stefanie
  id: a376de31-8972-11ed-ae7b-d0251c13c8ff
  last_name: Muroya Lei
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
citation:
  ama: 'Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. VAMOS: Middleware for best-effort
    third-party monitoring. <i>Science of Computer Programming</i>. 2025;240(2). doi:<a
    href="https://doi.org/10.1016/j.scico.2024.103212">10.1016/j.scico.2024.103212</a>'
  apa: 'Chalupa, M., Mühlböck, F., Muroya Lei, S., &#38; Henzinger, T. A. (2025).
    VAMOS: Middleware for best-effort third-party monitoring. <i>Science of Computer
    Programming</i>. Elsevier. <a href="https://doi.org/10.1016/j.scico.2024.103212">https://doi.org/10.1016/j.scico.2024.103212</a>'
  chicago: 'Chalupa, Marek, Fabian Mühlböck, Stefanie Muroya Lei, and Thomas A Henzinger.
    “VAMOS: Middleware for Best-Effort Third-Party Monitoring.” <i>Science of Computer
    Programming</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.scico.2024.103212">https://doi.org/10.1016/j.scico.2024.103212</a>.'
  ieee: 'M. Chalupa, F. Mühlböck, S. Muroya Lei, and T. A. Henzinger, “VAMOS: Middleware
    for best-effort third-party monitoring,” <i>Science of Computer Programming</i>,
    vol. 240, no. 2. Elsevier, 2025.'
  ista: 'Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. 2025. VAMOS: Middleware
    for best-effort third-party monitoring. Science of Computer Programming. 240(2),
    103212.'
  mla: 'Chalupa, Marek, et al. “VAMOS: Middleware for Best-Effort Third-Party Monitoring.”
    <i>Science of Computer Programming</i>, vol. 240, no. 2, 103212, Elsevier, 2025,
    doi:<a href="https://doi.org/10.1016/j.scico.2024.103212">10.1016/j.scico.2024.103212</a>.'
  short: M. Chalupa, F. Mühlböck, S. Muroya Lei, T.A. Henzinger, Science of Computer
    Programming 240 (2025).
corr_author: '1'
date_created: 2024-10-06T22:01:10Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2025-09-09T12:25:29Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1016/j.scico.2024.103212
ec_funded: 1
external_id:
  isi:
  - '001327852600001'
file:
- access_level: open_access
  checksum: cd93c0c356e479ffccfbe8499b6ba8e2
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  creator: dernst
  date_created: 2025-01-13T09:02:47Z
  date_updated: 2025-01-13T09:02:47Z
  file_id: '18831'
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  file_size: 1173677
  relation: main_file
  success: 1
file_date_updated: 2025-01-13T09:02:47Z
has_accepted_license: '1'
intvolume: '       240'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: Science of Computer Programming
publication_identifier:
  issn:
  - 0167-6423
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
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    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'VAMOS: Middleware for best-effort third-party monitoring'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 240
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18170'
abstract:
- lang: eng
  text: 'This study presents a graphene field-effect transistor (gFET) biosensor with
    dual detection capabilities for SARS-CoV-2: one RNA detection assay to confirm
    viral positivity and the other for nucleocapsid (N-)protein detection as a proxy
    for infectiousness of the patient. This technology can be rapidly adapted to emerging
    infectious diseases, making an essential tool to contain future pandemics. To
    detect viral RNA, the highly conserved E-gene of the virus was targeted, allowing
    for the determination of SARS-CoV-2 presence or absence using nasopharyngeal swab
    samples. For N-protein detection, specific antibodies were used. Tested on 213
    clinical nasopharyngeal samples, the gFET biosensor showed good correlation with
    RT-PCR cycle threshold values, proving its high sensitivity in detecting SARS-CoV-2
    RNA. Specificity was confirmed using 21 pre-pandemic samples positive for other
    respiratory viruses. The gFET biosensor had a limit of detection (LOD) for N-protein
    of 0.9 pM, establishing a foundation for the development of a sensitive tool for
    monitoring active viral infection. Results of gFET based N-protein detection corresponded
    to the results of virus culture in all 16 available clinical samples and thus
    it also proved its capability to serve as a proxy for infectivity. Overall, these
    findings support the potential of the gFET biosensor as a point-of-care device
    for rapid diagnosis of SARS-CoV-2 infection and indirect assessment of infectiousness
    in patients, providing additional information for clinical and public health decision-making.'
acknowledgement: 'This research was funded in whole by the Austrian Science Fund (FWF)
  [P 35103-B, Grant-DOI: 10.55776/P35103]. For open access purposes, the author has
  applied a CC BY public copyright license to any author-accepted manuscript version
  arising from this submission. We would like to thank Olfert Landt for advice on
  ssDNA probe design; Rui Qiang Chen, Jennifer Stock, and Christine Wukotitsch for
  their excellent support with ONT sequencing; Christoph Köppl and Andreas Fischer
  for excellent support in recombinant N protein expression and purification; and
  the whole team at the division of clinical virology for their support with standard
  diagnostics.'
article_number: '116807'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Anna Nele
  full_name: Herdina, Anna Nele
  last_name: Herdina
- first_name: Anil
  full_name: Bozdogan, Anil
  last_name: Bozdogan
- first_name: Patrik
  full_name: Aspermair, Patrik
  last_name: Aspermair
- first_name: Jakub
  full_name: Dostalek, Jakub
  last_name: Dostalek
- first_name: Miriam
  full_name: Klausberger, Miriam
  last_name: Klausberger
- first_name: Nico
  full_name: Lingg, Nico
  last_name: Lingg
- first_name: Monika
  full_name: Cserjan-Puschmann, Monika
  last_name: Cserjan-Puschmann
- first_name: Patricia Pereira
  full_name: Aguilar, Patricia Pereira
  last_name: Aguilar
- first_name: Simone
  full_name: Auer, Simone
  last_name: Auer
- first_name: Halil
  full_name: Demirtas, Halil
  last_name: Demirtas
- first_name: Jakob
  full_name: Andersson, Jakob
  id: 3a5f4167-9bd9-11ed-bd12-a1446d38776f
  last_name: Andersson
- first_name: Felix
  full_name: Lötsch, Felix
  last_name: Lötsch
- first_name: Barbara
  full_name: Holzer, Barbara
  last_name: Holzer
- first_name: Adi
  full_name: Steinrigl, Adi
  last_name: Steinrigl
- first_name: Florian
  full_name: Thalhammer, Florian
  last_name: Thalhammer
- first_name: Julia
  full_name: Schellnegger, Julia
  last_name: Schellnegger
- first_name: Monika
  full_name: Breuer, Monika
  last_name: Breuer
- first_name: Wolfgang
  full_name: Knoll, Wolfgang
  last_name: Knoll
- first_name: Robert
  full_name: Strassl, Robert
  last_name: Strassl
citation:
  ama: 'Herdina AN, Bozdogan A, Aspermair P, et al. Bridging basic science and applied
    diagnostics: Comprehensive viral diagnostics enabled by graphene-based electronic
    biosensor technology advancements. <i>Biosensors and Bioelectronics</i>. 2025;267.
    doi:<a href="https://doi.org/10.1016/j.bios.2024.116807">10.1016/j.bios.2024.116807</a>'
  apa: 'Herdina, A. N., Bozdogan, A., Aspermair, P., Dostalek, J., Klausberger, M.,
    Lingg, N., … Strassl, R. (2025). Bridging basic science and applied diagnostics:
    Comprehensive viral diagnostics enabled by graphene-based electronic biosensor
    technology advancements. <i>Biosensors and Bioelectronics</i>. Elsevier. <a href="https://doi.org/10.1016/j.bios.2024.116807">https://doi.org/10.1016/j.bios.2024.116807</a>'
  chicago: 'Herdina, Anna Nele, Anil Bozdogan, Patrik Aspermair, Jakub Dostalek, Miriam
    Klausberger, Nico Lingg, Monika Cserjan-Puschmann, et al. “Bridging Basic Science
    and Applied Diagnostics: Comprehensive Viral Diagnostics Enabled by Graphene-Based
    Electronic Biosensor Technology Advancements.” <i>Biosensors and Bioelectronics</i>.
    Elsevier, 2025. <a href="https://doi.org/10.1016/j.bios.2024.116807">https://doi.org/10.1016/j.bios.2024.116807</a>.'
  ieee: 'A. N. Herdina <i>et al.</i>, “Bridging basic science and applied diagnostics:
    Comprehensive viral diagnostics enabled by graphene-based electronic biosensor
    technology advancements,” <i>Biosensors and Bioelectronics</i>, vol. 267. Elsevier,
    2025.'
  ista: 'Herdina AN, Bozdogan A, Aspermair P, Dostalek J, Klausberger M, Lingg N,
    Cserjan-Puschmann M, Aguilar PP, Auer S, Demirtas H, Andersson J, Lötsch F, Holzer
    B, Steinrigl A, Thalhammer F, Schellnegger J, Breuer M, Knoll W, Strassl R. 2025.
    Bridging basic science and applied diagnostics: Comprehensive viral diagnostics
    enabled by graphene-based electronic biosensor technology advancements. Biosensors
    and Bioelectronics. 267, 116807.'
  mla: 'Herdina, Anna Nele, et al. “Bridging Basic Science and Applied Diagnostics:
    Comprehensive Viral Diagnostics Enabled by Graphene-Based Electronic Biosensor
    Technology Advancements.” <i>Biosensors and Bioelectronics</i>, vol. 267, 116807,
    Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.bios.2024.116807">10.1016/j.bios.2024.116807</a>.'
  short: A.N. Herdina, A. Bozdogan, P. Aspermair, J. Dostalek, M. Klausberger, N.
    Lingg, M. Cserjan-Puschmann, P.P. Aguilar, S. Auer, H. Demirtas, J. Andersson,
    F. Lötsch, B. Holzer, A. Steinrigl, F. Thalhammer, J. Schellnegger, M. Breuer,
    W. Knoll, R. Strassl, Biosensors and Bioelectronics 267 (2025).
date_created: 2024-10-06T22:01:11Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2025-02-27T12:34:07Z
day: '01'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1016/j.bios.2024.116807
external_id:
  isi:
  - '001328413700001'
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  - '39341071'
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language:
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month: '01'
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oa_version: Published Version
pmid: 1
publication: Biosensors and Bioelectronics
publication_identifier:
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  issn:
  - 0956-5663
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bridging basic science and applied diagnostics: Comprehensive viral diagnostics
  enabled by graphene-based electronic biosensor technology advancements'
tmp:
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  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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type: journal_article
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volume: 267
year: '2025'
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