---
_id: '12148'
abstract:
- lang: eng
  text: 'We prove a general local law for Wigner matrices that optimally handles observables
    of arbitrary rank and thus unifies the well-known averaged and isotropic local
    laws. As an application, we prove a central limit theorem in quantum unique ergodicity
    (QUE): that is, we show that the quadratic forms of a general deterministic matrix
    A on the bulk eigenvectors of a Wigner matrix have approximately Gaussian fluctuation.
    For the bulk spectrum, we thus generalise our previous result [17] as valid for
    test matrices A of large rank as well as the result of Benigni and Lopatto [7]
    as valid for specific small-rank observables.'
acknowledgement: L.E. acknowledges support by ERC Advanced Grant ‘RMTBeyond’ No. 101020331.
  D.S. acknowledges the support of Dr. Max Rössler, the Walter Haefner Foundation
  and the ETH Zürich Foundation.
article_number: e96
article_processing_charge: No
article_type: original
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. Rank-uniform local law for Wigner matrices.
    <i>Forum of Mathematics, Sigma</i>. 2022;10. doi:<a href="https://doi.org/10.1017/fms.2022.86">10.1017/fms.2022.86</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2022). Rank-uniform local
    law for Wigner matrices. <i>Forum of Mathematics, Sigma</i>. Cambridge University
    Press. <a href="https://doi.org/10.1017/fms.2022.86">https://doi.org/10.1017/fms.2022.86</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Rank-Uniform
    Local Law for Wigner Matrices.” <i>Forum of Mathematics, Sigma</i>. Cambridge
    University Press, 2022. <a href="https://doi.org/10.1017/fms.2022.86">https://doi.org/10.1017/fms.2022.86</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Rank-uniform local law for Wigner
    matrices,” <i>Forum of Mathematics, Sigma</i>, vol. 10. Cambridge University Press,
    2022.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2022. Rank-uniform local law for Wigner
    matrices. Forum of Mathematics, Sigma. 10, e96.
  mla: Cipolloni, Giorgio, et al. “Rank-Uniform Local Law for Wigner Matrices.” <i>Forum
    of Mathematics, Sigma</i>, vol. 10, e96, Cambridge University Press, 2022, doi:<a
    href="https://doi.org/10.1017/fms.2022.86">10.1017/fms.2022.86</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, Forum of Mathematics, Sigma 10 (2022).
corr_author: '1'
date_created: 2023-01-12T12:07:30Z
date_published: 2022-10-27T00:00:00Z
date_updated: 2025-04-14T07:57:18Z
day: '27'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1017/fms.2022.86
ec_funded: 1
external_id:
  isi:
  - '000873719200001'
file:
- access_level: open_access
  checksum: 94a049aeb1eea5497aa097712a73c400
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T10:02:40Z
  date_updated: 2023-01-24T10:02:40Z
  file_id: '12356'
  file_name: 2022_ForumMath_Cipolloni.pdf
  file_size: 817089
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T10:02:40Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
keyword:
- Computational Mathematics
- Discrete Mathematics and Combinatorics
- Geometry and Topology
- Mathematical Physics
- Statistics and Probability
- Algebra and Number Theory
- Theoretical Computer Science
- Analysis
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Forum of Mathematics, Sigma
publication_identifier:
  issn:
  - 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rank-uniform local law for Wigner matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2022'
...
---
_id: '12149'
abstract:
- lang: eng
  text: Editorial on the Research Topic
acknowledgement: This work was supported by a DFG grant ZA990/1 to DZ. This work was
  supported by the MSCA EU proposal 841301 - DREAM, European Commission; Horizon 2020
  - Research and Innovation Framework Programme to JFRV.
article_number: '1028154'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Giuditta
  full_name: Gambino, Giuditta
  last_name: Gambino
- first_name: Rebecca
  full_name: Bhik-Ghanie, Rebecca
  last_name: Bhik-Ghanie
- first_name: Giuseppe
  full_name: Giglia, Giuseppe
  last_name: Giglia
- first_name: M. Victoria
  full_name: Puig, M. Victoria
  last_name: Puig
- first_name: Juan F
  full_name: Ramirez Villegas, Juan F
  id: 44B06F76-F248-11E8-B48F-1D18A9856A87
  last_name: Ramirez Villegas
- first_name: Daniel
  full_name: Zaldivar, Daniel
  last_name: Zaldivar
citation:
  ama: 'Gambino G, Bhik-Ghanie R, Giglia G, Puig MV, Ramirez Villegas JF, Zaldivar
    D. Editorial: Neuromodulatory ascending systems: Their influence at the microscopic
    and macroscopic levels. <i>Frontiers in Neural Circuits</i>. 2022;16. doi:<a href="https://doi.org/10.3389/fncir.2022.1028154">10.3389/fncir.2022.1028154</a>'
  apa: 'Gambino, G., Bhik-Ghanie, R., Giglia, G., Puig, M. V., Ramirez Villegas, J.
    F., &#38; Zaldivar, D. (2022). Editorial: Neuromodulatory ascending systems: Their
    influence at the microscopic and macroscopic levels. <i>Frontiers in Neural Circuits</i>.
    Frontiers Media. <a href="https://doi.org/10.3389/fncir.2022.1028154">https://doi.org/10.3389/fncir.2022.1028154</a>'
  chicago: 'Gambino, Giuditta, Rebecca Bhik-Ghanie, Giuseppe Giglia, M. Victoria Puig,
    Juan F Ramirez Villegas, and Daniel Zaldivar. “Editorial: Neuromodulatory Ascending
    Systems: Their Influence at the Microscopic and Macroscopic Levels.” <i>Frontiers
    in Neural Circuits</i>. Frontiers Media, 2022. <a href="https://doi.org/10.3389/fncir.2022.1028154">https://doi.org/10.3389/fncir.2022.1028154</a>.'
  ieee: 'G. Gambino, R. Bhik-Ghanie, G. Giglia, M. V. Puig, J. F. Ramirez Villegas,
    and D. Zaldivar, “Editorial: Neuromodulatory ascending systems: Their influence
    at the microscopic and macroscopic levels,” <i>Frontiers in Neural Circuits</i>,
    vol. 16. Frontiers Media, 2022.'
  ista: 'Gambino G, Bhik-Ghanie R, Giglia G, Puig MV, Ramirez Villegas JF, Zaldivar
    D. 2022. Editorial: Neuromodulatory ascending systems: Their influence at the
    microscopic and macroscopic levels. Frontiers in Neural Circuits. 16, 1028154.'
  mla: 'Gambino, Giuditta, et al. “Editorial: Neuromodulatory Ascending Systems: Their
    Influence at the Microscopic and Macroscopic Levels.” <i>Frontiers in Neural Circuits</i>,
    vol. 16, 1028154, Frontiers Media, 2022, doi:<a href="https://doi.org/10.3389/fncir.2022.1028154">10.3389/fncir.2022.1028154</a>.'
  short: G. Gambino, R. Bhik-Ghanie, G. Giglia, M.V. Puig, J.F. Ramirez Villegas,
    D. Zaldivar, Frontiers in Neural Circuits 16 (2022).
date_created: 2023-01-12T12:07:39Z
date_published: 2022-10-26T00:00:00Z
date_updated: 2025-06-12T06:19:09Z
day: '26'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.3389/fncir.2022.1028154
ec_funded: 1
external_id:
  isi:
  - '000886671400001'
  pmid:
  - '36405671'
file:
- access_level: open_access
  checksum: 457aa00e1800847abb340853058531de
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T10:10:43Z
  date_updated: 2023-01-24T10:10:43Z
  file_id: '12357'
  file_name: 2022_FrontiersNeuralCircuits_Gambino.pdf
  file_size: 110031
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T10:10:43Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
keyword:
- Cellular and Molecular Neuroscience
- Cognitive Neuroscience
- Sensory Systems
- Neuroscience (miscellaneous)
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26BAE2E4-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '841301'
  name: 'The Brainstem-Hippocampus Network Uncovered: Dynamics, Reactivation and Memory
    Consolidation'
publication: Frontiers in Neural Circuits
publication_identifier:
  issn:
  - 1662-5110
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Editorial: Neuromodulatory ascending systems: Their influence at the microscopic
  and macroscopic levels'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2022'
...
---
_id: '12150'
abstract:
- lang: eng
  text: Methods inspired from machine learning have recently attracted great interest
    in the computational study of quantum many-particle systems. So far, however,
    it has proven challenging to deal with microscopic models in which the total number
    of particles is not conserved. To address this issue, we propose a variant of
    neural network states, which we term neural coherent states. Taking the Fröhlich
    impurity model as a case study, we show that neural coherent states can learn
    the ground state of nonadditive systems very well. In particular, we recover exact
    diagonalization in all regimes tested and observe substantial improvement over
    the standard coherent state estimates in the most challenging intermediate-coupling
    regime. Our approach is generic and does not assume specific details of the system,
    suggesting wide applications.
acknowledgement: 'We acknowledge fruitful discussions with G. Bighin, G. Fabiani,
  A. Ghazaryan, C. Lampert, and A. Volosniev at various stages of this work. W.R.
  acknowledges support through a DOC Fellowship of the Austrian Academy of Sciences
  and has received funding from the EU Horizon 2020 programme under the Marie Skłodowska-Curie
  Grant Agreement No. 665385. M.L. and J.H.M. acknowledge support by the European
  Research Council (ERC) Starting Grant No. 801770 (ANGULON) and Synergy Grant No.
  856538 (3D-MAGiC), respectively. This work is part of the Shell-NWO/FOMinitiative
  “Computational sciences for energy research” of Shell and Chemical Sciences, Earth
  and Life Sciences, Physical Sciences, FOM and STW. '
article_number: '155127'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Wojciech
  full_name: Rzadkowski, Wojciech
  id: 48C55298-F248-11E8-B48F-1D18A9856A87
  last_name: Rzadkowski
  orcid: 0000-0002-1106-4419
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Johan H.
  full_name: Mentink, Johan H.
  last_name: Mentink
citation:
  ama: Rzadkowski W, Lemeshko M, Mentink JH. Artificial neural network states for
    nonadditive systems. <i>Physical Review B</i>. 2022;106(15). doi:<a href="https://doi.org/10.1103/physrevb.106.155127">10.1103/physrevb.106.155127</a>
  apa: Rzadkowski, W., Lemeshko, M., &#38; Mentink, J. H. (2022). Artificial neural
    network states for nonadditive systems. <i>Physical Review B</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevb.106.155127">https://doi.org/10.1103/physrevb.106.155127</a>
  chicago: Rzadkowski, Wojciech, Mikhail Lemeshko, and Johan H. Mentink. “Artificial
    Neural Network States for Nonadditive Systems.” <i>Physical Review B</i>. American
    Physical Society, 2022. <a href="https://doi.org/10.1103/physrevb.106.155127">https://doi.org/10.1103/physrevb.106.155127</a>.
  ieee: W. Rzadkowski, M. Lemeshko, and J. H. Mentink, “Artificial neural network
    states for nonadditive systems,” <i>Physical Review B</i>, vol. 106, no. 15. American
    Physical Society, 2022.
  ista: Rzadkowski W, Lemeshko M, Mentink JH. 2022. Artificial neural network states
    for nonadditive systems. Physical Review B. 106(15), 155127.
  mla: Rzadkowski, Wojciech, et al. “Artificial Neural Network States for Nonadditive
    Systems.” <i>Physical Review B</i>, vol. 106, no. 15, 155127, American Physical
    Society, 2022, doi:<a href="https://doi.org/10.1103/physrevb.106.155127">10.1103/physrevb.106.155127</a>.
  short: W. Rzadkowski, M. Lemeshko, J.H. Mentink, Physical Review B 106 (2022).
date_created: 2023-01-12T12:07:49Z
date_published: 2022-10-15T00:00:00Z
date_updated: 2025-03-31T16:01:11Z
day: '15'
department:
- _id: MiLe
doi: 10.1103/physrevb.106.155127
ec_funded: 1
external_id:
  arxiv:
  - '2105.15193'
  isi:
  - '000875189100005'
intvolume: '       106'
isi: 1
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2105.15193'
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 05A235A0-7A3F-11EA-A408-12923DDC885E
  grant_number: '25681'
  name: Analytic and machine learning approaches to composite quantum impurities
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '801770'
  name: 'Angulon: physics and applications of a new quasiparticle'
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Artificial neural network states for nonadditive systems
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 106
year: '2022'
...
---
_id: '12151'
abstract:
- lang: eng
  text: The k-sample G(k,W) from a graphon W:[0,1]2→[0,1] is the random graph on {1,…,k},
    where we sample x1,…,xk∈[0,1] uniformly at random and make each pair {i,j}⊆{1,…,k}
    an edge with probability W(xi,xj), with all these choices being mutually independent.
    Let the random variable Xk(W) be the number of edges in  G(k,W). Vera T. Sós asked
    in 2012 whether two graphons U, W are necessarily weakly isomorphic if the random
    variables Xk(U) and Xk(W) have the same distribution for every integer k≥2. This
    question when one of the graphons W is a constant function was answered positively
    by Endre Csóka and independently by Jacob Fox, Tomasz Łuczak and Vera T. Sós.
    Here we investigate the question when W is a 2-step graphon and prove that the
    answer is positive for a 3-dimensional family of such graphons. We also present
    some related results.
acknowledgement: "Supported by Austrian Science Fund (FWF) Grant I3747. Supported
  by ERC Advanced Grant 101020255 and Leverhulme Research Project Grant RPG-2018-424.\r\nAn
  extended abstract of this paper appeared in the Proceedings of the European Conference\r\non
  Combinatorics, Graph Theory and Applications (EuroComb 2021), CRM Research Perspectives,
  Springer."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Oliver
  full_name: Cooley, Oliver
  id: 43f4ddd0-a46b-11ec-8df6-ef3703bd721d
  last_name: Cooley
- first_name: M.
  full_name: Kang, M.
  last_name: Kang
- first_name: O.
  full_name: Pikhurko, O.
  last_name: Pikhurko
citation:
  ama: Cooley O, Kang M, Pikhurko O. On a question of Vera T. Sós about size forcing
    of graphons. <i>Acta Mathematica Hungarica</i>. 2022;168:1-26. doi:<a href="https://doi.org/10.1007/s10474-022-01265-8">10.1007/s10474-022-01265-8</a>
  apa: Cooley, O., Kang, M., &#38; Pikhurko, O. (2022). On a question of Vera T. Sós
    about size forcing of graphons. <i>Acta Mathematica Hungarica</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s10474-022-01265-8">https://doi.org/10.1007/s10474-022-01265-8</a>
  chicago: Cooley, Oliver, M. Kang, and O. Pikhurko. “On a Question of Vera T. Sós
    about Size Forcing of Graphons.” <i>Acta Mathematica Hungarica</i>. Springer Nature,
    2022. <a href="https://doi.org/10.1007/s10474-022-01265-8">https://doi.org/10.1007/s10474-022-01265-8</a>.
  ieee: O. Cooley, M. Kang, and O. Pikhurko, “On a question of Vera T. Sós about size
    forcing of graphons,” <i>Acta Mathematica Hungarica</i>, vol. 168. Springer Nature,
    pp. 1–26, 2022.
  ista: Cooley O, Kang M, Pikhurko O. 2022. On a question of Vera T. Sós about size
    forcing of graphons. Acta Mathematica Hungarica. 168, 1–26.
  mla: Cooley, Oliver, et al. “On a Question of Vera T. Sós about Size Forcing of
    Graphons.” <i>Acta Mathematica Hungarica</i>, vol. 168, Springer Nature, 2022,
    pp. 1–26, doi:<a href="https://doi.org/10.1007/s10474-022-01265-8">10.1007/s10474-022-01265-8</a>.
  short: O. Cooley, M. Kang, O. Pikhurko, Acta Mathematica Hungarica 168 (2022) 1–26.
corr_author: '1'
date_created: 2023-01-12T12:07:59Z
date_published: 2022-11-23T00:00:00Z
date_updated: 2024-10-09T21:03:37Z
day: '23'
department:
- _id: MaKw
doi: 10.1007/s10474-022-01265-8
external_id:
  arxiv:
  - '2103.09114'
  isi:
  - '000886839900006'
intvolume: '       168'
isi: 1
keyword:
- graphon
- k-sample
- graphon forcing
- graph container
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2103.09114'
month: '11'
oa: 1
oa_version: Preprint
page: 1-26
publication: Acta Mathematica Hungarica
publication_identifier:
  eissn:
  - 1588-2632
  issn:
  - 0236-5294
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On a question of Vera T. Sós about size forcing of graphons
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 168
year: '2022'
...
---
_id: '12152'
abstract:
- lang: eng
  text: ESCRT-III filaments are composite cytoskeletal polymers that can constrict
    and cut cell membranes from the inside of the membrane neck. Membrane-bound ESCRT-III
    filaments undergo a series of dramatic composition and geometry changes in the
    presence of an ATP-consuming Vps4 enzyme, which causes stepwise changes in the
    membrane morphology. We set out to understand the physical mechanisms involved
    in translating the changes in ESCRT-III polymer composition into membrane deformation.
    We have built a coarse-grained model in which ESCRT-III polymers of different
    geometries and mechanical properties are allowed to copolymerise and bind to a
    deformable membrane. By modelling ATP-driven stepwise depolymerisation of specific
    polymers, we identify mechanical regimes in which changes in filament composition
    trigger the associated membrane transition from a flat to a buckled state, and
    then to a tubule state that eventually undergoes scission to release a small cargo-loaded
    vesicle. We then characterise how the location and kinetics of polymer loss affects
    the extent of membrane deformation and the efficiency of membrane neck scission.
    Our results identify the near-minimal mechanical conditions for the operation
    of shape-shifting composite polymers that sever membrane necks.
acknowledgement: "A.S . received an award from European Research Council (https://erc.europa.eu,
  “NEPA\"\r\n802960), and an award from the Royal Society (https://royalsociety.org,
  UF160266). L. H.-K.\r\nreceived an award from the Biotechnology and Biological Sciences
  Research Council (https://\r\nwww.ukri.org/councils/bbsrc/). E. L. received an award
  from the University College London (https://www.ucl.ac.uk/biophysics/news/2022/feb/applications-biop-brian-duff-and-ipls-summerundergraduate-studentships-now-open,
  Brian Duff Undergraduate Summer Research Studentship). B.B. and A.S. received an
  award from Volkswagen Foundation https://www.volkswagenstiftung.de/en/foundation,
  Az 96727), and an award from Medical Research Council (https://www.ukri.org/councils/mrc,
  MC_CF1226). A. R. received an\r\naward from the Swiss National Fund for Research
  (https://www.snf.ch/en, 31003A_130520,\r\n31003A_149975, and 31003A_173087) and
  an award from the European Research Council\r\nConsolidator (https://erc.europa.eu,
  311536). The funders had no role in study design, data collection and analysis,
  decision to publish, or preparation of the manuscript."
article_number: e1010586
article_processing_charge: No
article_type: original
author:
- first_name: Xiuyun
  full_name: Jiang, Xiuyun
  last_name: Jiang
- first_name: Lena
  full_name: Harker-Kirschneck, Lena
  last_name: Harker-Kirschneck
- first_name: Christian Eduardo
  full_name: Vanhille-Campos, Christian Eduardo
  id: 3adeca52-9313-11ed-b1ac-c170b2505714
  last_name: Vanhille-Campos
- first_name: Anna-Katharina
  full_name: Pfitzner, Anna-Katharina
  last_name: Pfitzner
- first_name: Elene
  full_name: Lominadze, Elene
  last_name: Lominadze
- first_name: Aurélien
  full_name: Roux, Aurélien
  last_name: Roux
- first_name: Buzz
  full_name: Baum, Buzz
  last_name: Baum
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
citation:
  ama: Jiang X, Harker-Kirschneck L, Vanhille-Campos CE, et al. Modelling membrane
    reshaping by staged polymerization of ESCRT-III filaments. <i>PLOS Computational
    Biology</i>. 2022;18(10). doi:<a href="https://doi.org/10.1371/journal.pcbi.1010586">10.1371/journal.pcbi.1010586</a>
  apa: Jiang, X., Harker-Kirschneck, L., Vanhille-Campos, C. E., Pfitzner, A.-K.,
    Lominadze, E., Roux, A., … Šarić, A. (2022). Modelling membrane reshaping by staged
    polymerization of ESCRT-III filaments. <i>PLOS Computational Biology</i>. Public
    Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1010586">https://doi.org/10.1371/journal.pcbi.1010586</a>
  chicago: Jiang, Xiuyun, Lena Harker-Kirschneck, Christian Eduardo Vanhille-Campos,
    Anna-Katharina Pfitzner, Elene Lominadze, Aurélien Roux, Buzz Baum, and Anđela
    Šarić. “Modelling Membrane Reshaping by Staged Polymerization of ESCRT-III Filaments.”
    <i>PLOS Computational Biology</i>. Public Library of Science, 2022. <a href="https://doi.org/10.1371/journal.pcbi.1010586">https://doi.org/10.1371/journal.pcbi.1010586</a>.
  ieee: X. Jiang <i>et al.</i>, “Modelling membrane reshaping by staged polymerization
    of ESCRT-III filaments,” <i>PLOS Computational Biology</i>, vol. 18, no. 10. Public
    Library of Science, 2022.
  ista: Jiang X, Harker-Kirschneck L, Vanhille-Campos CE, Pfitzner A-K, Lominadze
    E, Roux A, Baum B, Šarić A. 2022. Modelling membrane reshaping by staged polymerization
    of ESCRT-III filaments. PLOS Computational Biology. 18(10), e1010586.
  mla: Jiang, Xiuyun, et al. “Modelling Membrane Reshaping by Staged Polymerization
    of ESCRT-III Filaments.” <i>PLOS Computational Biology</i>, vol. 18, no. 10, e1010586,
    Public Library of Science, 2022, doi:<a href="https://doi.org/10.1371/journal.pcbi.1010586">10.1371/journal.pcbi.1010586</a>.
  short: X. Jiang, L. Harker-Kirschneck, C.E. Vanhille-Campos, A.-K. Pfitzner, E.
    Lominadze, A. Roux, B. Baum, A. Šarić, PLOS Computational Biology 18 (2022).
corr_author: '1'
date_created: 2023-01-12T12:08:10Z
date_published: 2022-10-17T00:00:00Z
date_updated: 2025-06-12T06:19:28Z
day: '17'
ddc:
- '570'
department:
- _id: AnSa
doi: 10.1371/journal.pcbi.1010586
ec_funded: 1
external_id:
  isi:
  - '000924885500005'
  pmid:
  - '36251703'
file:
- access_level: open_access
  checksum: bada6a7865e470cf42bbdfa67dd471d2
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T10:45:01Z
  date_updated: 2023-01-24T10:45:01Z
  file_id: '12359'
  file_name: 2022_PLoSCompBio_Jiang.pdf
  file_size: 2641067
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T10:45:01Z
has_accepted_license: '1'
intvolume: '        18'
isi: 1
issue: '10'
keyword:
- Computational Theory and Mathematics
- Cellular and Molecular Neuroscience
- Genetics
- Molecular Biology
- Ecology
- Modeling and Simulation
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: eba2549b-77a9-11ec-83b8-a81e493eae4e
  call_identifier: H2020
  grant_number: '802960'
  name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines'
- _id: eba0f67c-77a9-11ec-83b8-cc8501b3e222
  grant_number: '96752'
  name: 'The evolution of trafficking: from archaea to eukaryotes'
publication: PLOS Computational Biology
publication_identifier:
  issn:
  - 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/sharonJXY/3-filament-model
scopus_import: '1'
status: public
title: Modelling membrane reshaping by staged polymerization of ESCRT-III filaments
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2022'
...
---
_id: '12154'
abstract:
- lang: eng
  text: We review our theoretical results of the sound propagation in two-dimensional
    (2D) systems of ultracold fermionic and bosonic atoms. In the superfluid phase,
    characterized by the spontaneous symmetry breaking of the U(1) symmetry, there
    is the coexistence of first and second sound. In the case of weakly-interacting
    repulsive bosons, we model the recent measurements of the sound velocities of
    39K atoms in 2D obtained in the weakly-interacting regime and around the Berezinskii–Kosterlitz–Thouless
    (BKT) superfluid-to-normal transition temperature. In particular, we perform a
    quite accurate computation of the superfluid density and show that it is reasonably
    consistent with the experimental results. For superfluid attractive fermions,
    we calculate the first and second sound velocities across the whole BCS-BEC crossover.
    In the low-temperature regime, we reproduce the recent measurements of first-sound
    speed with 6Li atoms. We also predict that there is mixing between sound modes
    only in the finite-temperature BEC regime.
acknowledgement: "This research is partially supported by University of Padova, BIRD
  grant “Ultracold atoms\r\nin curved geometries”. KF is supported by Fondazione CARIPARO
  with a PhD fellowship. AT is\r\npartially supported by French National Research
  Agency ANR Grant Droplets N. ANR-19-CE30-0003-02. LS thanks Herwig Ott and Sandro
  Wimberger for their kind invitation to the\r\nInternational Workshop “Quantum Transport
  with ultracold atoms” (2022)."
article_number: '2182'
article_processing_charge: Yes
article_type: original
author:
- first_name: Luca
  full_name: Salasnich, Luca
  last_name: Salasnich
- first_name: Alberto
  full_name: Cappellaro, Alberto
  id: 9d13b3cb-30a2-11eb-80dc-f772505e8660
  last_name: Cappellaro
  orcid: 0000-0001-6110-2359
- first_name: Koichiro
  full_name: Furutani, Koichiro
  last_name: Furutani
- first_name: Andrea
  full_name: Tononi, Andrea
  last_name: Tononi
- first_name: Giacomo
  full_name: Bighin, Giacomo
  id: 4CA96FD4-F248-11E8-B48F-1D18A9856A87
  last_name: Bighin
  orcid: 0000-0001-8823-9777
citation:
  ama: Salasnich L, Cappellaro A, Furutani K, Tononi A, Bighin G. First and second
    sound in two-dimensional bosonic and fermionic superfluids. <i>Symmetry</i>. 2022;14(10).
    doi:<a href="https://doi.org/10.3390/sym14102182">10.3390/sym14102182</a>
  apa: Salasnich, L., Cappellaro, A., Furutani, K., Tononi, A., &#38; Bighin, G. (2022).
    First and second sound in two-dimensional bosonic and fermionic superfluids. <i>Symmetry</i>.
    MDPI. <a href="https://doi.org/10.3390/sym14102182">https://doi.org/10.3390/sym14102182</a>
  chicago: Salasnich, Luca, Alberto Cappellaro, Koichiro Furutani, Andrea Tononi,
    and Giacomo Bighin. “First and Second Sound in Two-Dimensional Bosonic and Fermionic
    Superfluids.” <i>Symmetry</i>. MDPI, 2022. <a href="https://doi.org/10.3390/sym14102182">https://doi.org/10.3390/sym14102182</a>.
  ieee: L. Salasnich, A. Cappellaro, K. Furutani, A. Tononi, and G. Bighin, “First
    and second sound in two-dimensional bosonic and fermionic superfluids,” <i>Symmetry</i>,
    vol. 14, no. 10. MDPI, 2022.
  ista: Salasnich L, Cappellaro A, Furutani K, Tononi A, Bighin G. 2022. First and
    second sound in two-dimensional bosonic and fermionic superfluids. Symmetry. 14(10),
    2182.
  mla: Salasnich, Luca, et al. “First and Second Sound in Two-Dimensional Bosonic
    and Fermionic Superfluids.” <i>Symmetry</i>, vol. 14, no. 10, 2182, MDPI, 2022,
    doi:<a href="https://doi.org/10.3390/sym14102182">10.3390/sym14102182</a>.
  short: L. Salasnich, A. Cappellaro, K. Furutani, A. Tononi, G. Bighin, Symmetry
    14 (2022).
date_created: 2023-01-12T12:08:31Z
date_published: 2022-10-17T00:00:00Z
date_updated: 2023-08-09T10:13:17Z
day: '17'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.3390/sym14102182
external_id:
  isi:
  - '000875039200001'
file:
- access_level: open_access
  checksum: 9b6bd0e484834dd76d7b26e3c5fba8bd
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T10:56:12Z
  date_updated: 2023-01-24T10:56:12Z
  file_id: '12361'
  file_name: 2022_Symmetry_Salsnich.pdf
  file_size: 843723
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T10:56:12Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
issue: '10'
keyword:
- Physics and Astronomy (miscellaneous)
- General Mathematics
- Chemistry (miscellaneous)
- Computer Science (miscellaneous)
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: Symmetry
publication_identifier:
  issn:
  - 2073-8994
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: First and second sound in two-dimensional bosonic and fermionic superfluids
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2022'
...
---
_id: '12155'
abstract:
- lang: eng
  text: The growing demand of thermal management in various fields such as miniaturized
    5G chips has motivated researchers to develop new and high-performance solid-state
    refrigeration technologies, typically including multicaloric and thermoelectric
    (TE) cooling. Among them, TE cooling has attracted huge attention owing to its
    advantages of rapid response, large cooling temperature difference, high stability,
    and tunable device size. Bi2Te3-based alloys have long been the only commercialized
    TE cooling materials, while novel systems SnSe and Mg3(Bi,Sb)2 have recently been
    discovered as potential candidates. However, challenges and problems still require
    to be summarized and further resolved for realizing better cooling performance.
    In this review, we systematically investigate TE cooling from its internal mechanism,
    crucial parameters, to device design and applications. Furthermore, we summarize
    the current optimization strategies for existing TE cooling materials, and finally
    provide some personal prospects especially the material-planification concept
    on future research on establishing better TE cooling.
acknowledgement: We acknowledge support from the National Key Research and Development
  Program of China (2018YFA0702100), the National Natural Science Foundation of China
  (51571007, 51772012, 52002011 and 52002042), the Basic Science Center Project of
  National Natural Science Foundation of China (51788104), Beijing Natural Science
  Foundation (JQ18004), 111 Project (B17002), and the National Science Fund for Distinguished
  Young Scholars (51925101).
article_processing_charge: No
article_type: original
author:
- first_name: Yongxin
  full_name: Qin, Yongxin
  last_name: Qin
- first_name: Bingchao
  full_name: Qin, Bingchao
  last_name: Qin
- first_name: Dongyang
  full_name: Wang, Dongyang
  last_name: Wang
- first_name: Cheng
  full_name: Chang, Cheng
  id: 9E331C2E-9F27-11E9-AE48-5033E6697425
  last_name: Chang
  orcid: 0000-0002-9515-4277
- first_name: Li-Dong
  full_name: Zhao, Li-Dong
  last_name: Zhao
citation:
  ama: 'Qin Y, Qin B, Wang D, Chang C, Zhao L-D. Solid-state cooling: Thermoelectrics.
    <i>Energy &#38; Environmental Science</i>. 2022;15(11):4527-4541. doi:<a href="https://doi.org/10.1039/d2ee02408j">10.1039/d2ee02408j</a>'
  apa: 'Qin, Y., Qin, B., Wang, D., Chang, C., &#38; Zhao, L.-D. (2022). Solid-state
    cooling: Thermoelectrics. <i>Energy &#38; Environmental Science</i>. Royal Society
    of Chemistry. <a href="https://doi.org/10.1039/d2ee02408j">https://doi.org/10.1039/d2ee02408j</a>'
  chicago: 'Qin, Yongxin, Bingchao Qin, Dongyang Wang, Cheng Chang, and Li-Dong Zhao.
    “Solid-State Cooling: Thermoelectrics.” <i>Energy &#38; Environmental Science</i>.
    Royal Society of Chemistry, 2022. <a href="https://doi.org/10.1039/d2ee02408j">https://doi.org/10.1039/d2ee02408j</a>.'
  ieee: 'Y. Qin, B. Qin, D. Wang, C. Chang, and L.-D. Zhao, “Solid-state cooling:
    Thermoelectrics,” <i>Energy &#38; Environmental Science</i>, vol. 15, no. 11.
    Royal Society of Chemistry, pp. 4527–4541, 2022.'
  ista: 'Qin Y, Qin B, Wang D, Chang C, Zhao L-D. 2022. Solid-state cooling: Thermoelectrics.
    Energy &#38; Environmental Science. 15(11), 4527–4541.'
  mla: 'Qin, Yongxin, et al. “Solid-State Cooling: Thermoelectrics.” <i>Energy &#38;
    Environmental Science</i>, vol. 15, no. 11, Royal Society of Chemistry, 2022,
    pp. 4527–41, doi:<a href="https://doi.org/10.1039/d2ee02408j">10.1039/d2ee02408j</a>.'
  short: Y. Qin, B. Qin, D. Wang, C. Chang, L.-D. Zhao, Energy &#38; Environmental
    Science 15 (2022) 4527–4541.
date_created: 2023-01-12T12:08:41Z
date_published: 2022-11-01T00:00:00Z
date_updated: 2024-01-22T08:13:43Z
day: '01'
department:
- _id: MaIb
doi: 10.1039/d2ee02408j
external_id:
  isi:
  - '000863642400001'
intvolume: '        15'
isi: 1
issue: '11'
keyword:
- Pollution
- Nuclear Energy and Engineering
- Renewable Energy
- Sustainability and the Environment
- Environmental Chemistry
language:
- iso: eng
month: '11'
oa_version: None
page: 4527-4541
publication: Energy & Environmental Science
publication_identifier:
  eissn:
  - 1754-5706
  issn:
  - 1754-5692
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1039/d3ee90067c
scopus_import: '1'
status: public
title: 'Solid-state cooling: Thermoelectrics'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2022'
...
---
_id: '12156'
abstract:
- lang: eng
  text: Models of transcriptional regulation that assume equilibrium binding of transcription
    factors have been less successful at predicting gene expression from sequence
    in eukaryotes than in bacteria. This could be due to the non-equilibrium nature
    of eukaryotic regulation. Unfortunately, the space of possible non-equilibrium
    mechanisms is vast and predominantly uninteresting. The key question is therefore
    how this space can be navigated efficiently, to focus on mechanisms and models
    that are biologically relevant. In this review, we advocate for the normative
    role of theory—theory that prescribes rather than just describes—in providing
    such a focus. Theory should expand its remit beyond inferring mechanistic models
    from data, towards identifying non-equilibrium gene regulatory schemes that may
    have been evolutionarily selected, despite their energy consumption, because they
    are precise, reliable, fast, or otherwise outperform regulation at equilibrium.
    We illustrate our reasoning by toy examples for which we provide simulation code.
acknowledgement: 'This work was supported through the Center for the Physics of Biological
  Function (PHYe1734030) and by National Institutes of Health Grants R01GM097275 and
  U01DK127429 (TG). GT acknowledges the support of the Austrian Science Fund grant
  FWF P28844 and the Human Frontiers Science Program. '
article_number: '100435'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Benjamin
  full_name: Zoller, Benjamin
  last_name: Zoller
- first_name: Thomas
  full_name: Gregor, Thomas
  last_name: Gregor
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: '1'
citation:
  ama: Zoller B, Gregor T, Tkačik G. Eukaryotic gene regulation at equilibrium, or
    non? <i>Current Opinion in Systems Biology</i>. 2022;31(9). doi:<a href="https://doi.org/10.1016/j.coisb.2022.100435">10.1016/j.coisb.2022.100435</a>
  apa: Zoller, B., Gregor, T., &#38; Tkačik, G. (2022). Eukaryotic gene regulation
    at equilibrium, or non? <i>Current Opinion in Systems Biology</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.coisb.2022.100435">https://doi.org/10.1016/j.coisb.2022.100435</a>
  chicago: Zoller, Benjamin, Thomas Gregor, and Gašper Tkačik. “Eukaryotic Gene Regulation
    at Equilibrium, or Non?” <i>Current Opinion in Systems Biology</i>. Elsevier,
    2022. <a href="https://doi.org/10.1016/j.coisb.2022.100435">https://doi.org/10.1016/j.coisb.2022.100435</a>.
  ieee: B. Zoller, T. Gregor, and G. Tkačik, “Eukaryotic gene regulation at equilibrium,
    or non?,” <i>Current Opinion in Systems Biology</i>, vol. 31, no. 9. Elsevier,
    2022.
  ista: Zoller B, Gregor T, Tkačik G. 2022. Eukaryotic gene regulation at equilibrium,
    or non? Current Opinion in Systems Biology. 31(9), 100435.
  mla: Zoller, Benjamin, et al. “Eukaryotic Gene Regulation at Equilibrium, or Non?”
    <i>Current Opinion in Systems Biology</i>, vol. 31, no. 9, 100435, Elsevier, 2022,
    doi:<a href="https://doi.org/10.1016/j.coisb.2022.100435">10.1016/j.coisb.2022.100435</a>.
  short: B. Zoller, T. Gregor, G. Tkačik, Current Opinion in Systems Biology 31 (2022).
corr_author: '1'
date_created: 2023-01-12T12:08:51Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-06-11T13:47:43Z
day: '01'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1016/j.coisb.2022.100435
external_id:
  pmid:
  - '36590072'
file:
- access_level: open_access
  checksum: 97ef01e0cc60cdc84f45640a0f248fb0
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T12:14:10Z
  date_updated: 2023-01-24T12:14:10Z
  file_id: '12362'
  file_name: 2022_CurrentBiology_Zoller.pdf
  file_size: 2214944
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T12:14:10Z
has_accepted_license: '1'
intvolume: '        31'
issue: '9'
keyword:
- Applied Mathematics
- Computer Science Applications
- Drug Discovery
- General Biochemistry
- Genetics and Molecular Biology
- Modeling and Simulation
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: Current Opinion in Systems Biology
publication_identifier:
  issn:
  - 2452-3100
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Eukaryotic gene regulation at equilibrium, or non?
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 31
year: '2022'
...
---
_id: '12157'
abstract:
- lang: eng
  text: 'Polygenic adaptation is thought to be ubiquitous, yet remains poorly understood.
    Here, we model this process analytically, in the plausible setting of a highly
    polygenic, quantitative trait that experiences a sudden shift in the fitness optimum.
    We show how the mean phenotype changes over time, depending on the effect sizes
    of loci that contribute to variance in the trait, and characterize the allele
    dynamics at these loci. Notably, we describe the two phases of the allele dynamics:
    The first is a rapid phase, in which directional selection introduces small frequency
    differences between alleles whose effects are aligned with or opposed to the shift,
    ultimately leading to small differences in their probability of fixation during
    a second, longer phase, governed by stabilizing selection. As we discuss, key
    results should hold in more general settings and have important implications for
    efforts to identify the genetic basis of adaptation in humans and other species.'
acknowledgement: "We thank Guy Amster, Jeremy Berg, Nick Barton, Yuval Simons and
  Molly Przeworski for many helpful discussions, and Jeremy Berg, Graham Coop, Joachim
  Hermisson, Guillaume Martin, Will Milligan, Peter Ralph, Yuval Simons, Leo Speidel
  and Molly Przeworski for comments on the manuscript.\r\nNational Institutes of Health
  GM115889 Laura Katharine Hayward Guy Sella \r\nNational Institutes of Health GM121372
  Laura Katharine Hayward"
article_number: '66697'
article_processing_charge: No
article_type: original
author:
- first_name: Laura
  full_name: Hayward, Laura
  id: fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b
  last_name: Hayward
- first_name: Guy
  full_name: Sella, Guy
  last_name: Sella
citation:
  ama: Hayward L, Sella G. Polygenic adaptation after a sudden change in environment.
    <i>eLife</i>. 2022;11. doi:<a href="https://doi.org/10.7554/elife.66697">10.7554/elife.66697</a>
  apa: Hayward, L., &#38; Sella, G. (2022). Polygenic adaptation after a sudden change
    in environment. <i>ELife</i>. eLife Sciences Publications. <a href="https://doi.org/10.7554/elife.66697">https://doi.org/10.7554/elife.66697</a>
  chicago: Hayward, Laura, and Guy Sella. “Polygenic Adaptation after a Sudden Change
    in Environment.” <i>ELife</i>. eLife Sciences Publications, 2022. <a href="https://doi.org/10.7554/elife.66697">https://doi.org/10.7554/elife.66697</a>.
  ieee: L. Hayward and G. Sella, “Polygenic adaptation after a sudden change in environment,”
    <i>eLife</i>, vol. 11. eLife Sciences Publications, 2022.
  ista: Hayward L, Sella G. 2022. Polygenic adaptation after a sudden change in environment.
    eLife. 11, 66697.
  mla: Hayward, Laura, and Guy Sella. “Polygenic Adaptation after a Sudden Change
    in Environment.” <i>ELife</i>, vol. 11, 66697, eLife Sciences Publications, 2022,
    doi:<a href="https://doi.org/10.7554/elife.66697">10.7554/elife.66697</a>.
  short: L. Hayward, G. Sella, ELife 11 (2022).
corr_author: '1'
date_created: 2023-01-12T12:09:00Z
date_published: 2022-09-26T00:00:00Z
date_updated: 2024-10-09T21:03:38Z
day: '26'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.7554/elife.66697
external_id:
  isi:
  - '000890735600001'
file:
- access_level: open_access
  checksum: 28de155b231ac1c8d4501c98b2fb359a
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-24T12:21:32Z
  date_updated: 2023-01-24T12:21:32Z
  file_id: '12363'
  file_name: 2022_eLife_Hayward.pdf
  file_size: 18935612
  relation: main_file
  success: 1
file_date_updated: 2023-01-24T12:21:32Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
  eissn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polygenic adaptation after a sudden change in environment
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2022'
...
---
_id: '12160'
abstract:
- lang: eng
  text: We present the Filecoin Hierarchical Consensus framework, which aims to overcome
    the throughput challenges of blockchain consensus by horizontally scaling the
    network. Unlike traditional sharding designs, based on partitioning the state
    of the network, our solution centers on the concept of subnets -which are organized
    hierarchically- and can be spawned on-demand to manage new state. Child sub nets
    are firewalled from parent subnets, have their own specific policies, and run
    a different consensus algorithm, increasing the network capacity and enabling
    new applications. Moreover, they benefit from the security of parent subnets by
    periodically checkpointing state. In this paper, we introduce the overall system
    architecture, our detailed designs for cross-net transaction handling, and the
    open questions that we are still exploring.
article_processing_charge: No
author:
- first_name: Alfonso
  full_name: De la Rocha, Alfonso
  last_name: De la Rocha
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Jorge M.
  full_name: Soares, Jorge M.
  last_name: Soares
- first_name: Marko
  full_name: Vukolic, Marko
  last_name: Vukolic
citation:
  ama: 'De la Rocha A, Kokoris Kogias E, Soares JM, Vukolic M. Hierarchical consensus:
    A horizontal scaling framework for blockchains. In: <i>42nd International Conference
    on Distributed Computing Systems Workshops</i>. Vol 2022. Institute of Electrical
    and Electronics Engineers; 2022:45-52. doi:<a href="https://doi.org/10.1109/icdcsw56584.2022.00018">10.1109/icdcsw56584.2022.00018</a>'
  apa: 'De la Rocha, A., Kokoris Kogias, E., Soares, J. M., &#38; Vukolic, M. (2022).
    Hierarchical consensus: A horizontal scaling framework for blockchains. In <i>42nd
    International Conference on Distributed Computing Systems Workshops</i> (Vol.
    2022, pp. 45–52). Bologna, Italy: Institute of Electrical and Electronics Engineers.
    <a href="https://doi.org/10.1109/icdcsw56584.2022.00018">https://doi.org/10.1109/icdcsw56584.2022.00018</a>'
  chicago: 'De la Rocha, Alfonso, Eleftherios Kokoris Kogias, Jorge M. Soares, and
    Marko Vukolic. “Hierarchical Consensus: A Horizontal Scaling Framework for Blockchains.”
    In <i>42nd International Conference on Distributed Computing Systems Workshops</i>,
    2022:45–52. Institute of Electrical and Electronics Engineers, 2022. <a href="https://doi.org/10.1109/icdcsw56584.2022.00018">https://doi.org/10.1109/icdcsw56584.2022.00018</a>.'
  ieee: 'A. De la Rocha, E. Kokoris Kogias, J. M. Soares, and M. Vukolic, “Hierarchical
    consensus: A horizontal scaling framework for blockchains,” in <i>42nd International
    Conference on Distributed Computing Systems Workshops</i>, Bologna, Italy, 2022,
    vol. 2022, pp. 45–52.'
  ista: 'De la Rocha A, Kokoris Kogias E, Soares JM, Vukolic M. 2022. Hierarchical
    consensus: A horizontal scaling framework for blockchains. 42nd International
    Conference on Distributed Computing Systems Workshops. ICDCSW: International Conference
    on Distributed Computing Systems Workshop vol. 2022, 45–52.'
  mla: 'De la Rocha, Alfonso, et al. “Hierarchical Consensus: A Horizontal Scaling
    Framework for Blockchains.” <i>42nd International Conference on Distributed Computing
    Systems Workshops</i>, vol. 2022, Institute of Electrical and Electronics Engineers,
    2022, pp. 45–52, doi:<a href="https://doi.org/10.1109/icdcsw56584.2022.00018">10.1109/icdcsw56584.2022.00018</a>.'
  short: A. De la Rocha, E. Kokoris Kogias, J.M. Soares, M. Vukolic, in:, 42nd International
    Conference on Distributed Computing Systems Workshops, Institute of Electrical
    and Electronics Engineers, 2022, pp. 45–52.
conference:
  end_date: 2022-07-10
  location: Bologna, Italy
  name: 'ICDCSW: International Conference on Distributed Computing Systems Workshop'
  start_date: 2022-07-10
date_created: 2023-01-12T12:09:28Z
date_published: 2022-11-29T00:00:00Z
date_updated: 2023-08-04T09:06:02Z
day: '29'
department:
- _id: ElKo
doi: 10.1109/icdcsw56584.2022.00018
external_id:
  isi:
  - '000895984800009'
intvolume: '      2022'
isi: 1
language:
- iso: eng
month: '11'
oa_version: None
page: 45-52
publication: 42nd International Conference on Distributed Computing Systems Workshops
publication_identifier:
  eisbn:
  - '9781665488792'
  eissn:
  - 2332-5666
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Hierarchical consensus: A horizontal scaling framework for blockchains'
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2022
year: '2022'
...
---
_id: '12161'
abstract:
- lang: eng
  text: 'We introduce LIMES, a new method for learning with non-stationary streaming
    data, inspired by the recent success of meta-learning. The main idea is not to
    attempt to learn a single classifier that would have to work well across all occurring
    data distributions, nor many separate classifiers, but to exploit a hybrid strategy:
    we learn a single set of model parameters from which a specific classifier for
    any specific data distribution is derived via classifier adaptation. Assuming
    a multiclass classification setting with class-prior shift, the adaptation step
    can be performed analytically with only the classifier’s bias terms being affected.
    Another contribution of our work is an extrapolation step that predicts suitable
    adaptation parameters for future time steps based on the previous data. In combination,
    we obtain a lightweight procedure for learning from streaming data with varying
    class distribution that adds no trainable parameters and almost no memory or computational
    overhead compared to training a single model. Experiments on a set of exemplary
    tasks using Twitter data show that LIMES achieves higher accuracy than alternative
    approaches, especially with respect to the relevant real-world metric of lowest
    within-day accuracy.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Paulina
  full_name: Tomaszewska, Paulina
  last_name: Tomaszewska
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Tomaszewska P, Lampert C. Lightweight conditional model extrapolation for
    streaming data under class-prior shift. In: <i>26th International Conference on
    Pattern Recognition</i>. Vol 2022. Institute of Electrical and Electronics Engineers;
    2022:2128-2134. doi:<a href="https://doi.org/10.1109/icpr56361.2022.9956195">10.1109/icpr56361.2022.9956195</a>'
  apa: 'Tomaszewska, P., &#38; Lampert, C. (2022). Lightweight conditional model extrapolation
    for streaming data under class-prior shift. In <i>26th International Conference
    on Pattern Recognition</i> (Vol. 2022, pp. 2128–2134). Montreal, Canada: Institute
    of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/icpr56361.2022.9956195">https://doi.org/10.1109/icpr56361.2022.9956195</a>'
  chicago: Tomaszewska, Paulina, and Christoph Lampert. “Lightweight Conditional Model
    Extrapolation for Streaming Data under Class-Prior Shift.” In <i>26th International
    Conference on Pattern Recognition</i>, 2022:2128–34. Institute of Electrical and
    Electronics Engineers, 2022. <a href="https://doi.org/10.1109/icpr56361.2022.9956195">https://doi.org/10.1109/icpr56361.2022.9956195</a>.
  ieee: P. Tomaszewska and C. Lampert, “Lightweight conditional model extrapolation
    for streaming data under class-prior shift,” in <i>26th International Conference
    on Pattern Recognition</i>, Montreal, Canada, 2022, vol. 2022, pp. 2128–2134.
  ista: 'Tomaszewska P, Lampert C. 2022. Lightweight conditional model extrapolation
    for streaming data under class-prior shift. 26th International Conference on Pattern
    Recognition. ICPR: International Conference on Pattern Recognition vol. 2022,
    2128–2134.'
  mla: Tomaszewska, Paulina, and Christoph Lampert. “Lightweight Conditional Model
    Extrapolation for Streaming Data under Class-Prior Shift.” <i>26th International
    Conference on Pattern Recognition</i>, vol. 2022, Institute of Electrical and
    Electronics Engineers, 2022, pp. 2128–34, doi:<a href="https://doi.org/10.1109/icpr56361.2022.9956195">10.1109/icpr56361.2022.9956195</a>.
  short: P. Tomaszewska, C. Lampert, in:, 26th International Conference on Pattern
    Recognition, Institute of Electrical and Electronics Engineers, 2022, pp. 2128–2134.
conference:
  end_date: 2022-08-25
  location: Montreal, Canada
  name: 'ICPR: International Conference on Pattern Recognition'
  start_date: 2022-08-21
corr_author: '1'
date_created: 2023-01-12T12:09:38Z
date_published: 2022-11-29T00:00:00Z
date_updated: 2024-10-09T21:03:41Z
day: '29'
department:
- _id: ChLa
doi: 10.1109/icpr56361.2022.9956195
external_id:
  arxiv:
  - '2206.05181'
  isi:
  - '000897707602018'
intvolume: '      2022'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2206.05181
month: '11'
oa: 1
oa_version: Preprint
page: 2128-2134
publication: 26th International Conference on Pattern Recognition
publication_identifier:
  eisbn:
  - '9781665490627'
  eissn:
  - 2831-7475
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lightweight conditional model extrapolation for streaming data under class-prior
  shift
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2022
year: '2022'
...
---
_id: '12167'
abstract:
- lang: eng
  text: "Payment channels effectively move the transaction load off-chain thereby
    successfully addressing the inherent scalability problem most cryptocurrencies
    face. A major drawback of payment channels is the need to “top up” funds on-chain
    when a channel is depleted. Rebalancing was proposed to alleviate this issue,
    where parties with depleting channels move their funds along a cycle to replenish
    their channels off-chain. Protocols for rebalancing so far either introduce local
    solutions or compromise privacy.\r\nIn this work, we present an opt-in rebalancing
    protocol that is both private and globally optimal, meaning our protocol maximizes
    the total amount of rebalanced funds. We study rebalancing from the framework
    of linear programming. To obtain full privacy guarantees, we leverage multi-party
    computation in solving the linear program, which is executed by selected participants
    to maintain efficiency. Finally, we efficiently decompose the rebalancing solution
    into incentive-compatible cycles which conserve user balances when executed atomically."
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Georgia
  full_name: Avarikioti, Georgia
  id: c20482a0-3b89-11eb-9862-88cf6404b88c
  last_name: Avarikioti
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Iosif
  full_name: Salem, Iosif
  last_name: Salem
- first_name: Stefan
  full_name: Schmid, Stefan
  last_name: Schmid
- first_name: Samarth
  full_name: Tiwari, Samarth
  last_name: Tiwari
- first_name: Michelle X
  full_name: Yeo, Michelle X
  id: 2D82B818-F248-11E8-B48F-1D18A9856A87
  last_name: Yeo
  orcid: 0009-0001-3676-4809
citation:
  ama: 'Avarikioti G, Pietrzak KZ, Salem I, Schmid S, Tiwari S, Yeo MX. Hide &#38;
    Seek: Privacy-preserving rebalancing on payment channel networks. In: <i>Financial
    Cryptography and Data Security</i>. Vol 13411. Springer Nature; 2022:358-373.
    doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_17">10.1007/978-3-031-18283-9_17</a>'
  apa: 'Avarikioti, G., Pietrzak, K. Z., Salem, I., Schmid, S., Tiwari, S., &#38;
    Yeo, M. X. (2022). Hide &#38; Seek: Privacy-preserving rebalancing on payment
    channel networks. In <i>Financial Cryptography and Data Security</i> (Vol. 13411,
    pp. 358–373). Grenada: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-18283-9_17">https://doi.org/10.1007/978-3-031-18283-9_17</a>'
  chicago: 'Avarikioti, Georgia, Krzysztof Z Pietrzak, Iosif Salem, Stefan Schmid,
    Samarth Tiwari, and Michelle X Yeo. “Hide &#38; Seek: Privacy-Preserving Rebalancing
    on Payment Channel Networks.” In <i>Financial Cryptography and Data Security</i>,
    13411:358–73. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-18283-9_17">https://doi.org/10.1007/978-3-031-18283-9_17</a>.'
  ieee: 'G. Avarikioti, K. Z. Pietrzak, I. Salem, S. Schmid, S. Tiwari, and M. X.
    Yeo, “Hide &#38; Seek: Privacy-preserving rebalancing on payment channel networks,”
    in <i>Financial Cryptography and Data Security</i>, Grenada, 2022, vol. 13411,
    pp. 358–373.'
  ista: 'Avarikioti G, Pietrzak KZ, Salem I, Schmid S, Tiwari S, Yeo MX. 2022. Hide
    &#38; Seek: Privacy-preserving rebalancing on payment channel networks. Financial
    Cryptography and Data Security. FC: Financial Cryptography and Data Security,
    LNCS, vol. 13411, 358–373.'
  mla: 'Avarikioti, Georgia, et al. “Hide &#38; Seek: Privacy-Preserving Rebalancing
    on Payment Channel Networks.” <i>Financial Cryptography and Data Security</i>,
    vol. 13411, Springer Nature, 2022, pp. 358–73, doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_17">10.1007/978-3-031-18283-9_17</a>.'
  short: G. Avarikioti, K.Z. Pietrzak, I. Salem, S. Schmid, S. Tiwari, M.X. Yeo, in:,
    Financial Cryptography and Data Security, Springer Nature, 2022, pp. 358–373.
conference:
  end_date: 2022-05-06
  location: Grenada
  name: 'FC: Financial Cryptography and Data Security'
  start_date: 2022-05-02
date_created: 2023-01-12T12:10:38Z
date_published: 2022-10-22T00:00:00Z
date_updated: 2025-09-10T09:48:15Z
day: '22'
department:
- _id: KrPi
doi: 10.1007/978-3-031-18283-9_17
external_id:
  arxiv:
  - '2110.08848'
  isi:
  - '001423640200017'
intvolume: '     13411'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2110.08848
month: '10'
oa: 1
oa_version: Preprint
page: 358-373
publication: Financial Cryptography and Data Security
publication_identifier:
  eisbn:
  - '9783031182839'
  eissn:
  - 1611-3349
  isbn:
  - '9783031182822'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Hide & Seek: Privacy-preserving rebalancing on payment channel networks'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13411
year: '2022'
...
---
OA_place: repository
OA_type: green
_id: '12168'
abstract:
- lang: eng
  text: "Advances in blockchains have influenced the State-Machine-Replication (SMR)
    world and many state-of-the-art blockchain-SMR solutions are based on two pillars:
    Chaining and Leader-rotation. A predetermined round-robin mechanism used for Leader-rotation,
    however, has an undesirable behavior: crashed parties become designated leaders
    infinitely often, slowing down overall system performance. In this paper, we provide
    a new Leader-Aware SMR framework that, among other desirable properties, formalizes
    a Leader-utilization requirement that bounds the number of rounds whose leaders
    are faulty in crash-only executions.\r\nWe introduce Carousel, a novel, reputation-based
    Leader-rotation solution to achieve Leader-Aware SMR. The challenge in adaptive
    Leader-rotation is that it cannot rely on consensus to determine a leader, since
    consensus itself needs a leader. Carousel uses the available on-chain information
    to determine a leader locally and achieves Liveness despite this difficulty. A
    HotStuff implementation fitted with Carousel demonstrates drastic performance
    improvements: it increases throughput over 2x in faultless settings and provided
    a 20x throughput increase and 5x latency reduction in the presence of faults."
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Shir
  full_name: Cohen, Shir
  last_name: Cohen
- first_name: Rati
  full_name: Gelashvili, Rati
  last_name: Gelashvili
- first_name: Eleftherios
  full_name: Kokoris Kogias, Eleftherios
  id: f5983044-d7ef-11ea-ac6d-fd1430a26d30
  last_name: Kokoris Kogias
- first_name: Zekun
  full_name: Li, Zekun
  last_name: Li
- first_name: Dahlia
  full_name: Malkhi, Dahlia
  last_name: Malkhi
- first_name: Alberto
  full_name: Sonnino, Alberto
  last_name: Sonnino
- first_name: Alexander
  full_name: Spiegelman, Alexander
  last_name: Spiegelman
citation:
  ama: 'Cohen S, Gelashvili R, Kokoris Kogias E, et al. Be aware of your leaders.
    In: <i>International Conference on Financial Cryptography and Data Security</i>.
    Vol 13411. Springer Nature; 2022:279-295. doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_13">10.1007/978-3-031-18283-9_13</a>'
  apa: 'Cohen, S., Gelashvili, R., Kokoris Kogias, E., Li, Z., Malkhi, D., Sonnino,
    A., &#38; Spiegelman, A. (2022). Be aware of your leaders. In <i>International
    Conference on Financial Cryptography and Data Security</i> (Vol. 13411, pp. 279–295).
    Grenada: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-18283-9_13">https://doi.org/10.1007/978-3-031-18283-9_13</a>'
  chicago: Cohen, Shir, Rati Gelashvili, Eleftherios Kokoris Kogias, Zekun Li, Dahlia
    Malkhi, Alberto Sonnino, and Alexander Spiegelman. “Be Aware of Your Leaders.”
    In <i>International Conference on Financial Cryptography and Data Security</i>,
    13411:279–95. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-18283-9_13">https://doi.org/10.1007/978-3-031-18283-9_13</a>.
  ieee: S. Cohen <i>et al.</i>, “Be aware of your leaders,” in <i>International Conference
    on Financial Cryptography and Data Security</i>, Grenada, 2022, vol. 13411, pp.
    279–295.
  ista: 'Cohen S, Gelashvili R, Kokoris Kogias E, Li Z, Malkhi D, Sonnino A, Spiegelman
    A. 2022. Be aware of your leaders. International Conference on Financial Cryptography
    and Data Security. FC: Financial Cryptography and Data Security, LNCS, vol. 13411,
    279–295.'
  mla: Cohen, Shir, et al. “Be Aware of Your Leaders.” <i>International Conference
    on Financial Cryptography and Data Security</i>, vol. 13411, Springer Nature,
    2022, pp. 279–95, doi:<a href="https://doi.org/10.1007/978-3-031-18283-9_13">10.1007/978-3-031-18283-9_13</a>.
  short: S. Cohen, R. Gelashvili, E. Kokoris Kogias, Z. Li, D. Malkhi, A. Sonnino,
    A. Spiegelman, in:, International Conference on Financial Cryptography and Data
    Security, Springer Nature, 2022, pp. 279–295.
conference:
  end_date: 2022-05-06
  location: Grenada
  name: 'FC: Financial Cryptography and Data Security'
  start_date: 2022-05-02
date_created: 2023-01-12T12:10:49Z
date_published: 2022-10-22T00:00:00Z
date_updated: 2025-09-10T09:48:54Z
day: '22'
department:
- _id: ElKo
doi: 10.1007/978-3-031-18283-9_13
external_id:
  arxiv:
  - '2110.00960'
  isi:
  - '001423640200013'
intvolume: '     13411'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2110.00960
month: '10'
oa: 1
oa_version: Preprint
page: 279-295
publication: International Conference on Financial Cryptography and Data Security
publication_identifier:
  eisbn:
  - '9783031182839'
  eissn:
  - 1611-3349
  isbn:
  - '9783031182822'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Be aware of your leaders
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13411
year: '2022'
...
---
_id: '12170'
abstract:
- lang: eng
  text: We present PET, a specialized and highly optimized framework for partial exploration
    on probabilistic systems. Over the last decade, several significant advances in
    the analysis of Markov decision processes employed partial exploration. In a nutshell,
    this idea allows to focus computation on specific parts of the system, guided
    by heuristics, while maintaining correctness. In particular, only relevant parts
    of the system are constructed on demand, which in turn potentially allows to omit
    constructing large parts of the system. Depending on the model, this leads to
    dramatic speed-ups, in extreme cases even up to an arbitrary factor. PET unifies
    several previous implementations and provides a flexible framework to easily implement
    partial exploration for many further problems. Our experimental evaluation shows
    significant improvements compared to the previous implementations while vastly
    reducing the overhead required to add support for additional properties.
acknowledgement: We thank Pranav Ashok and Maximilian Weininger for their contributions
  to spiritual predecessors of PET as well as motivating the initial development of
  this tool.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Tobias
  full_name: Meggendorfer, Tobias
  id: b21b0c15-30a2-11eb-80dc-f13ca25802e1
  last_name: Meggendorfer
  orcid: 0000-0002-1712-2165
citation:
  ama: 'Meggendorfer T. PET – A partial exploration tool for probabilistic verification.
    In: <i>20th International Symposium on Automated Technology for Verification and
    Analysis</i>. Vol 13505. Springer Nature; 2022:320-326. doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_20">10.1007/978-3-031-19992-9_20</a>'
  apa: 'Meggendorfer, T. (2022). PET – A partial exploration tool for probabilistic
    verification. In <i>20th International Symposium on Automated Technology for Verification
    and Analysis</i> (Vol. 13505, pp. 320–326). Virtual: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19992-9_20">https://doi.org/10.1007/978-3-031-19992-9_20</a>'
  chicago: Meggendorfer, Tobias. “PET – A Partial Exploration Tool for Probabilistic
    Verification.” In <i>20th International Symposium on Automated Technology for
    Verification and Analysis</i>, 13505:320–26. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19992-9_20">https://doi.org/10.1007/978-3-031-19992-9_20</a>.
  ieee: T. Meggendorfer, “PET – A partial exploration tool for probabilistic verification,”
    in <i>20th International Symposium on Automated Technology for Verification and
    Analysis</i>, Virtual, 2022, vol. 13505, pp. 320–326.
  ista: 'Meggendorfer T. 2022. PET – A partial exploration tool for probabilistic
    verification. 20th International Symposium on Automated Technology for Verification
    and Analysis. ATVA: Automated Technology for Verification and Analysis, LNCS,
    vol. 13505, 320–326.'
  mla: Meggendorfer, Tobias. “PET – A Partial Exploration Tool for Probabilistic Verification.”
    <i>20th International Symposium on Automated Technology for Verification and Analysis</i>,
    vol. 13505, Springer Nature, 2022, pp. 320–26, doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_20">10.1007/978-3-031-19992-9_20</a>.
  short: T. Meggendorfer, in:, 20th International Symposium on Automated Technology
    for Verification and Analysis, Springer Nature, 2022, pp. 320–326.
conference:
  end_date: 2022-10-28
  location: Virtual
  name: 'ATVA: Automated Technology for Verification and Analysis'
  start_date: 2022-10-25
corr_author: '1'
date_created: 2023-01-12T12:11:07Z
date_published: 2022-10-21T00:00:00Z
date_updated: 2025-09-10T09:49:29Z
day: '21'
department:
- _id: KrCh
doi: 10.1007/978-3-031-19992-9_20
external_id:
  isi:
  - '001456146500020'
intvolume: '     13505'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 320-326
publication: 20th International Symposium on Automated Technology for Verification
  and Analysis
publication_identifier:
  eisbn:
  - '9783031199929'
  eissn:
  - 1611-3349
  isbn:
  - '9783031199912'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: PET – A partial exploration tool for probabilistic verification
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13505
year: '2022'
...
---
_id: '12171'
abstract:
- lang: eng
  text: 'We propose an algorithmic approach for synthesizing linear hybrid automata
    from time-series data. Unlike existing approaches, our approach provides a whole
    family of models with the same discrete structure but different dynamics. Each
    model in the family is guaranteed to capture the input data up to a precision
    error ε, in the following sense: For each time series, the model contains an execution
    that is ε-close to the data points. Our construction allows to effectively choose
    a model from this family with minimal precision error ε. We demonstrate the algorithm’s
    efficiency and its ability to find precise models in two case studies.'
acknowledgement: This work was supported in part by the European Union’s Horizon 2020
  research and innovation programme under the Marie Skłodowska-Curie grant agreement
  no. 847635, by the ERC-2020-AdG 101020093, by DIREC - Digital Research Centre Denmark,
  and by the Villum Investigator Grant S4OS.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Miriam
  full_name: Garcia Soto, Miriam
  id: 4B3207F6-F248-11E8-B48F-1D18A9856A87
  last_name: Garcia Soto
  orcid: 0000-0003-2936-5719
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Christian
  full_name: Schilling, Christian
  id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
  last_name: Schilling
  orcid: 0000-0003-3658-1065
citation:
  ama: 'Garcia Soto M, Henzinger TA, Schilling C. Synthesis of parametric hybrid automata
    from time series. In: <i>20th International Symposium on Automated Technology
    for Verification and Analysis</i>. Vol 13505. Springer Nature; 2022:337-353. doi:<a
    href="https://doi.org/10.1007/978-3-031-19992-9_22">10.1007/978-3-031-19992-9_22</a>'
  apa: 'Garcia Soto, M., Henzinger, T. A., &#38; Schilling, C. (2022). Synthesis of parametric
    hybrid automata from time series. In <i>20th International Symposium on Automated
    Technology for Verification and Analysis</i> (Vol. 13505, pp. 337–353). Virtual:
    Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19992-9_22">https://doi.org/10.1007/978-3-031-19992-9_22</a>'
  chicago: Garcia Soto, Miriam, Thomas A Henzinger, and Christian Schilling. “Synthesis
    of Parametric Hybrid Automata from Time Series.” In <i>20th International Symposium
    on Automated Technology for Verification and Analysis</i>, 13505:337–53. Springer
    Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19992-9_22">https://doi.org/10.1007/978-3-031-19992-9_22</a>.
  ieee: M. Garcia Soto, T. A. Henzinger, and C. Schilling, “Synthesis of parametric
    hybrid automata from time series,” in <i>20th International Symposium on Automated
    Technology for Verification and Analysis</i>, Virtual, 2022, vol. 13505, pp. 337–353.
  ista: 'Garcia Soto M, Henzinger TA, Schilling C. 2022. Synthesis of parametric hybrid
    automata from time series. 20th International Symposium on Automated Technology
    for Verification and Analysis. ATVA: Automated Technology for Verification and
    Analysis, LNCS, vol. 13505, 337–353.'
  mla: Garcia Soto, Miriam, et al. “Synthesis of Parametric Hybrid Automata from Time
    Series.” <i>20th International Symposium on Automated Technology for Verification
    and Analysis</i>, vol. 13505, Springer Nature, 2022, pp. 337–53, doi:<a href="https://doi.org/10.1007/978-3-031-19992-9_22">10.1007/978-3-031-19992-9_22</a>.
  short: M. Garcia Soto, T.A. Henzinger, C. Schilling, in:, 20th International Symposium
    on Automated Technology for Verification and Analysis, Springer Nature, 2022,
    pp. 337–353.
conference:
  end_date: 2022-10-28
  location: Virtual
  name: 'ATVA: Automated Technology for Verification and Analysis'
  start_date: 2022-10-25
corr_author: '1'
date_created: 2023-01-12T12:11:16Z
date_published: 2022-10-21T00:00:00Z
date_updated: 2025-09-10T09:50:08Z
day: '21'
department:
- _id: ToHe
doi: 10.1007/978-3-031-19992-9_22
ec_funded: 1
external_id:
  arxiv:
  - '2208.06383'
  isi:
  - '001456146500022'
intvolume: '     13505'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2208.06383
month: '10'
oa: 1
oa_version: Preprint
page: 337-353
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 20th International Symposium on Automated Technology for Verification
  and Analysis
publication_identifier:
  eisbn:
  - '9783031199929'
  eissn:
  - 1611-3349
  isbn:
  - '9783031199912'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis of parametric hybrid automata from time series
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13505
year: '2022'
...
---
_id: '12173'
abstract:
- lang: eng
  text: With increasing urbanization and industrialization, the prevalence of inflammatory
    bowel diseases (IBDs) has steadily been rising over the past two decades. IBD
    involves flares of gastrointestinal (GI) inflammation accompanied by microbiota
    perturbations. However, microbial mechanisms that trigger such flares remain elusive.
    Here, we analyzed the association of the emerging pathogen atypical enteropathogenic
    E. coli (aEPEC) with IBD disease activity. The presence of diarrheagenic E. coli
    was assessed in stool samples from 630 IBD patients and 234 age- and sex-matched
    controls without GI symptoms. Microbiota was analyzed with 16S ribosomal RNA gene
    amplicon sequencing, and 57 clinical aEPEC isolates were subjected to whole-genome
    sequencing and in vitro pathogenicity experiments including biofilm formation,
    epithelial barrier function and the ability to induce pro-inflammatory signaling.
    The presence of aEPEC correlated with laboratory, clinical and endoscopic disease
    activity in ulcerative colitis (UC), as well as microbiota dysbiosis. In vitro,
    aEPEC strains induce epithelial p21-activated kinases, disrupt the epithelial
    barrier and display potent biofilm formation. The effector proteins espV and espG2
    distinguish aEPEC cultured from UC and Crohn’s disease patients, respectively.
    EspV-positive aEPEC harbor more virulence factors and have a higher pro-inflammatory
    potential, which is counteracted by 5-ASA. aEPEC may tip a fragile immune–microbiota
    homeostasis and thereby contribute to flares in UC. aEPEC isolates from UC patients
    display properties to disrupt the epithelial barrier and to induce pro-inflammatory
    signaling in vitro.
acknowledgement: "We would like to acknowledge Anita Krnjic, Christina Gmainer, Marion
  Nehr, Helga Mock, and Sena Ecin for technical support in conducting the experiments.\r\nThis
  study was supported by the Austrian Science Fund (P 32302) and the Vienna Science
  and Technology Fund (LS18- 053; Austrian Science Fund (FWF)) [P 32302]."
article_number: e2143218
article_processing_charge: No
article_type: original
author:
- first_name: Maximilian
  full_name: Baumgartner, Maximilian
  last_name: Baumgartner
- first_name: Rebecca
  full_name: Zirnbauer, Rebecca
  last_name: Zirnbauer
- first_name: Sabine
  full_name: Schlager, Sabine
  last_name: Schlager
- first_name: Daniel
  full_name: Mertens, Daniel
  last_name: Mertens
- first_name: Nikolaus
  full_name: Gasche, Nikolaus
  last_name: Gasche
- first_name: Barbara
  full_name: Sladek, Barbara
  last_name: Sladek
- first_name: Craig
  full_name: Herbold, Craig
  last_name: Herbold
- first_name: Olga
  full_name: Bochkareva, Olga
  last_name: Bochkareva
- first_name: Vera
  full_name: Emelianenko, Vera
  id: 20152b9d-927a-11ed-8107-be36d740812d
  last_name: Emelianenko
- first_name: Harald
  full_name: Vogelsang, Harald
  last_name: Vogelsang
- first_name: Michaela
  full_name: Lang, Michaela
  last_name: Lang
- first_name: Anton
  full_name: Klotz, Anton
  last_name: Klotz
- first_name: Birgit
  full_name: Moik, Birgit
  last_name: Moik
- first_name: Athanasios
  full_name: Makristathis, Athanasios
  last_name: Makristathis
- first_name: David
  full_name: Berry, David
  last_name: Berry
- first_name: Stefanie
  full_name: Dabsch, Stefanie
  last_name: Dabsch
- first_name: Vineeta
  full_name: Khare, Vineeta
  last_name: Khare
- first_name: Christoph
  full_name: Gasche, Christoph
  last_name: Gasche
citation:
  ama: Baumgartner M, Zirnbauer R, Schlager S, et al. Atypical enteropathogenic E.
    coli are associated with disease activity in ulcerative colitis. <i>Gut Microbes</i>.
    2022;14(1). doi:<a href="https://doi.org/10.1080/19490976.2022.2143218">10.1080/19490976.2022.2143218</a>
  apa: Baumgartner, M., Zirnbauer, R., Schlager, S., Mertens, D., Gasche, N., Sladek,
    B., … Gasche, C. (2022). Atypical enteropathogenic E. coli are associated with
    disease activity in ulcerative colitis. <i>Gut Microbes</i>. Taylor &#38; Francis.
    <a href="https://doi.org/10.1080/19490976.2022.2143218">https://doi.org/10.1080/19490976.2022.2143218</a>
  chicago: Baumgartner, Maximilian, Rebecca Zirnbauer, Sabine Schlager, Daniel Mertens,
    Nikolaus Gasche, Barbara Sladek, Craig Herbold, et al. “Atypical Enteropathogenic
    E. Coli Are Associated with Disease Activity in Ulcerative Colitis.” <i>Gut Microbes</i>.
    Taylor &#38; Francis, 2022. <a href="https://doi.org/10.1080/19490976.2022.2143218">https://doi.org/10.1080/19490976.2022.2143218</a>.
  ieee: M. Baumgartner <i>et al.</i>, “Atypical enteropathogenic E. coli are associated
    with disease activity in ulcerative colitis,” <i>Gut Microbes</i>, vol. 14, no.
    1. Taylor &#38; Francis, 2022.
  ista: Baumgartner M, Zirnbauer R, Schlager S, Mertens D, Gasche N, Sladek B, Herbold
    C, Bochkareva O, Emelianenko V, Vogelsang H, Lang M, Klotz A, Moik B, Makristathis
    A, Berry D, Dabsch S, Khare V, Gasche C. 2022. Atypical enteropathogenic E. coli
    are associated with disease activity in ulcerative colitis. Gut Microbes. 14(1),
    e2143218.
  mla: Baumgartner, Maximilian, et al. “Atypical Enteropathogenic E. Coli Are Associated
    with Disease Activity in Ulcerative Colitis.” <i>Gut Microbes</i>, vol. 14, no.
    1, e2143218, Taylor &#38; Francis, 2022, doi:<a href="https://doi.org/10.1080/19490976.2022.2143218">10.1080/19490976.2022.2143218</a>.
  short: M. Baumgartner, R. Zirnbauer, S. Schlager, D. Mertens, N. Gasche, B. Sladek,
    C. Herbold, O. Bochkareva, V. Emelianenko, H. Vogelsang, M. Lang, A. Klotz, B.
    Moik, A. Makristathis, D. Berry, S. Dabsch, V. Khare, C. Gasche, Gut Microbes
    14 (2022).
date_created: 2023-01-12T12:11:36Z
date_published: 2022-11-22T00:00:00Z
date_updated: 2025-06-11T13:39:40Z
day: '22'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1080/19490976.2022.2143218
external_id:
  isi:
  - '000889180100001'
  pmid:
  - '36415023'
file:
- access_level: open_access
  checksum: ee7681a17ae27645e9b5c1df61c15429
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-26T10:56:51Z
  date_updated: 2023-01-26T10:56:51Z
  file_id: '12400'
  file_name: 2022_GutMicrobes_Baumgartner.pdf
  file_size: 4075251
  relation: main_file
  success: 1
file_date_updated: 2023-01-26T10:56:51Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
issue: '1'
keyword:
- Infectious Diseases
- Microbiology (medical)
- Gastroenterology
- Microbiology
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Gut Microbes
publication_identifier:
  eissn:
  - 1949-0984
  issn:
  - 1949-0976
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: Atypical enteropathogenic E. coli are associated with disease activity in ulcerative
  colitis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2022'
...
---
_id: '12174'
abstract:
- lang: eng
  text: "Vacuolar-type H+-ATPase (V-ATPase) is a multimeric complex present in a variety
    of cellular membranes that acts as an ATP-dependent proton pump and plays a key
    role in pH homeostasis and intracellular signalling pathways. In humans, 22 autosomal
    genes encode for a redundant set of subunits allowing the composition of diverse
    V-ATPase complexes with specific properties and expression. Sixteen subunits have
    been linked to human disease.\r\nHere we describe 26 patients harbouring 20 distinct
    pathogenic de novo missense ATP6V1A variants, mainly clustering within the ATP
    synthase α/β family-nucleotide-binding domain. At a mean age of 7 years (extremes:
    6 weeks, youngest deceased patient to 22 years, oldest patient) clinical pictures
    included early lethal encephalopathies with rapidly progressive massive brain
    atrophy, severe developmental epileptic encephalopathies and static intellectual
    disability with epilepsy. The first clinical manifestation was early hypotonia,
    in 70%; 81% developed epilepsy, manifested as developmental epileptic encephalopathies
    in 58% of the cohort and with infantile spasms in 62%; 63% of developmental epileptic
    encephalopathies failed to achieve any developmental, communicative or motor skills.
    Less severe outcomes were observed in 23% of patients who, at a mean age of 10
    years and 6 months, exhibited moderate intellectual disability, with independent
    walking and variable epilepsy. None of the patients developed communicative language.
    Microcephaly (38%) and amelogenesis imperfecta/enamel dysplasia (42%) were additional
    clinical features. Brain MRI demonstrated hypomyelination and generalized atrophy
    in 68%. Atrophy was progressive in all eight individuals undergoing repeated MRIs.</jats:p>\r\n
    \              <jats:p>Fibroblasts of two patients with developmental epileptic
    encephalopathies showed decreased LAMP1 expression, Lysotracker staining and increased
    organelle pH, consistent with lysosomal impairment and loss of V-ATPase function.
    Fibroblasts of two patients with milder disease, exhibited a different phenotype
    with increased Lysotracker staining, decreased organelle pH and no significant
    modification in LAMP1 expression. Quantification of substrates for lysosomal enzymes
    in cellular extracts from four patients revealed discrete accumulation. Transmission
    electron microscopy of fibroblasts of four patients with variable severity and
    of induced pluripotent stem cell-derived neurons from two patients with developmental
    epileptic encephalopathies showed electron-dense inclusions, lipid droplets, osmiophilic
    material and lamellated membrane structures resembling phospholipids. Quantitative
    assessment in induced pluripotent stem cell-derived neurons identified significantly
    smaller lysosomes.\r\nATP6V1A-related encephalopathy represents a new paradigm
    among lysosomal disorders. It results from a dysfunctional endo-lysosomal membrane
    protein causing altered pH homeostasis. Its pathophysiology implies intracellular
    accumulation of substrates whose composition remains unclear, and a combination
    of developmental brain abnormalities and neurodegenerative changes established
    during prenatal and early postanal development, whose severity is variably determined
    by specific pathogenic variants."
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all patients and family members for their participation
  in this study. We thank Melanie Pieraks and Eva Reinthaler (Neurolentech, Austria)
  for generating the human iPSC lines and\r\nfor performing quality checks. We thank
  Vanessa Zheden and Daniel Gütl for their excellent technical support in the specimen
  preparation for transmission electron microscopy and Flavia Leite for preparing
  the lentiviruses. The support from Electron Microscopy Facility and Molecular Biology
  Services at IST Austria is greatly acknowledged. We would like to thank Doctors
  Jane Hurst and Richard Scott for their help in retrieving the detailed clinical
  information of Patient 17. The research team acknowledges the support of the National
  Institute for Health Research, through the Comprehensive Clinical Research Network.
  See Supplementary Material for Undiagnosed Disease Network consortium details. Genetic
  information on Patient 23 was made available through access to the data and findings
  generated by the 100 000 Genomes\r\nProject; www.genomicsengland.co.uk (to K.L.).
  \r\nThis work was supported by the EU 7th Framework Programme (FP7) under the project
  DESIRE grant N602531 (to R.G.); the Regione Toscana under the Call for Health 2018
  (grant\r\nDECODE-EE) (to R.G.); the ‘Brain Project’ by Fondazione Cassa di Risparmio
  di Firenze (to R.G.); IRCCS Ospedale Policlinico San Martino 5×1000 and Ricerca
  Corrente (to A.F. and F.B.). The European Reference Network (ERN) for rare and complex
  epilepsies (EpiCARE) provided financial support for meetings organization. The DDD
  study presents independent research commissioned by the Health Innovation Challenge
  Fund (grant number HICF-1009-003), a parallel funding partnership between Wellcome
  and the Department of Health, and the Wellcome Sanger Institute (grant number WT098051).
  The views expressed in this publication\r\nare those of the author(s) and not necessarily
  those of Wellcome or the Department of Health. The study has UK Research Ethics
  Committee approval (10/H0305/83, granted by the Cambridge South REC, and GEN/284/12
  granted by the Republic of Ireland REC). This study makes use of DECIPHER (https://www.deciphergenomics.org),
  which is funded by Wellcome. K.K.-S. was supported by the ISTplus fellowship. "
article_processing_charge: No
article_type: original
author:
- first_name: Renzo
  full_name: Guerrini, Renzo
  last_name: Guerrini
- first_name: Davide
  full_name: Mei, Davide
  last_name: Mei
- first_name: Margit Katalin
  full_name: Szigeti, Margit Katalin
  id: 44F4BDC0-F248-11E8-B48F-1D18A9856A87
  last_name: Szigeti
  orcid: 0000-0001-9500-8758
- first_name: Sara
  full_name: Pepe, Sara
  last_name: Pepe
- first_name: Mary Kay
  full_name: Koenig, Mary Kay
  last_name: Koenig
- first_name: Gretchen
  full_name: Von Allmen, Gretchen
  last_name: Von Allmen
- first_name: Megan T
  full_name: Cho, Megan T
  last_name: Cho
- first_name: Kimberly
  full_name: McDonald, Kimberly
  last_name: McDonald
- first_name: Janice
  full_name: Baker, Janice
  last_name: Baker
- first_name: Vikas
  full_name: Bhambhani, Vikas
  last_name: Bhambhani
- first_name: Zöe
  full_name: Powis, Zöe
  last_name: Powis
- first_name: Lance
  full_name: Rodan, Lance
  last_name: Rodan
- first_name: Rima
  full_name: Nabbout, Rima
  last_name: Nabbout
- first_name: Giulia
  full_name: Barcia, Giulia
  last_name: Barcia
- first_name: Jill A
  full_name: Rosenfeld, Jill A
  last_name: Rosenfeld
- first_name: Carlos A
  full_name: Bacino, Carlos A
  last_name: Bacino
- first_name: Cyril
  full_name: Mignot, Cyril
  last_name: Mignot
- first_name: Lillian H
  full_name: Power, Lillian H
  last_name: Power
- first_name: Catharine J
  full_name: Harris, Catharine J
  last_name: Harris
- first_name: Dragan
  full_name: Marjanovic, Dragan
  last_name: Marjanovic
- first_name: Rikke S
  full_name: Møller, Rikke S
  last_name: Møller
- first_name: Trine B
  full_name: Hammer, Trine B
  last_name: Hammer
- first_name: Riikka
  full_name: Keski Filppula, Riikka
  last_name: Keski Filppula
- first_name: Päivi
  full_name: Vieira, Päivi
  last_name: Vieira
- first_name: Clara
  full_name: Hildebrandt, Clara
  last_name: Hildebrandt
- first_name: Stephanie
  full_name: Sacharow, Stephanie
  last_name: Sacharow
- first_name: Luca
  full_name: Maragliano, Luca
  last_name: Maragliano
- first_name: Fabio
  full_name: Benfenati, Fabio
  last_name: Benfenati
- first_name: Katherine
  full_name: Lachlan, Katherine
  last_name: Lachlan
- first_name: Andreas
  full_name: Benneche, Andreas
  last_name: Benneche
- first_name: Florence
  full_name: Petit, Florence
  last_name: Petit
- first_name: Jean Madeleine
  full_name: de Sainte Agathe, Jean Madeleine
  last_name: de Sainte Agathe
- first_name: Barbara
  full_name: Hallinan, Barbara
  last_name: Hallinan
- first_name: Yue
  full_name: Si, Yue
  last_name: Si
- first_name: Ingrid M
  full_name: Wentzensen, Ingrid M
  last_name: Wentzensen
- first_name: Fanggeng
  full_name: Zou, Fanggeng
  last_name: Zou
- first_name: Vinodh
  full_name: Narayanan, Vinodh
  last_name: Narayanan
- first_name: Naomichi
  full_name: Matsumoto, Naomichi
  last_name: Matsumoto
- first_name: Alessandra
  full_name: Boncristiano, Alessandra
  last_name: Boncristiano
- first_name: Giancarlo
  full_name: la Marca, Giancarlo
  last_name: la Marca
- first_name: Mitsuhiro
  full_name: Kato, Mitsuhiro
  last_name: Kato
- first_name: Kristin
  full_name: Anderson, Kristin
  last_name: Anderson
- first_name: Carmen
  full_name: Barba, Carmen
  last_name: Barba
- first_name: Luisa
  full_name: Sturiale, Luisa
  last_name: Sturiale
- first_name: Domenico
  full_name: Garozzo, Domenico
  last_name: Garozzo
- first_name: Roberto
  full_name: Bei, Roberto
  last_name: Bei
- first_name: Laura
  full_name: Masuelli, Laura
  last_name: Masuelli
- first_name: Valerio
  full_name: Conti, Valerio
  last_name: Conti
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Anna
  full_name: Fassio, Anna
  last_name: Fassio
citation:
  ama: 'Guerrini R, Mei D, Szigeti MK, et al. Phenotypic and genetic spectrum of ATP6V1A
    encephalopathy: A disorder of lysosomal homeostasis. <i>Brain</i>. 2022;145(8):2687-2703.
    doi:<a href="https://doi.org/10.1093/brain/awac145">10.1093/brain/awac145</a>'
  apa: 'Guerrini, R., Mei, D., Szigeti, M. K., Pepe, S., Koenig, M. K., Von Allmen,
    G., … Fassio, A. (2022). Phenotypic and genetic spectrum of ATP6V1A encephalopathy:
    A disorder of lysosomal homeostasis. <i>Brain</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/brain/awac145">https://doi.org/10.1093/brain/awac145</a>'
  chicago: 'Guerrini, Renzo, Davide Mei, Margit Katalin Szigeti, Sara Pepe, Mary Kay
    Koenig, Gretchen Von Allmen, Megan T Cho, et al. “Phenotypic and Genetic Spectrum
    of ATP6V1A Encephalopathy: A Disorder of Lysosomal Homeostasis.” <i>Brain</i>.
    Oxford University Press, 2022. <a href="https://doi.org/10.1093/brain/awac145">https://doi.org/10.1093/brain/awac145</a>.'
  ieee: 'R. Guerrini <i>et al.</i>, “Phenotypic and genetic spectrum of ATP6V1A encephalopathy:
    A disorder of lysosomal homeostasis,” <i>Brain</i>, vol. 145, no. 8. Oxford University
    Press, pp. 2687–2703, 2022.'
  ista: 'Guerrini R, Mei D, Szigeti MK, Pepe S, Koenig MK, Von Allmen G, Cho MT, McDonald
    K, Baker J, Bhambhani V, Powis Z, Rodan L, Nabbout R, Barcia G, Rosenfeld JA,
    Bacino CA, Mignot C, Power LH, Harris CJ, Marjanovic D, Møller RS, Hammer TB,
    Keski Filppula R, Vieira P, Hildebrandt C, Sacharow S, Maragliano L, Benfenati
    F, Lachlan K, Benneche A, Petit F, de Sainte Agathe JM, Hallinan B, Si Y, Wentzensen
    IM, Zou F, Narayanan V, Matsumoto N, Boncristiano A, la Marca G, Kato M, Anderson
    K, Barba C, Sturiale L, Garozzo D, Bei R, Masuelli L, Conti V, Novarino G, Fassio
    A. 2022. Phenotypic and genetic spectrum of ATP6V1A encephalopathy: A disorder
    of lysosomal homeostasis. Brain. 145(8), 2687–2703.'
  mla: 'Guerrini, Renzo, et al. “Phenotypic and Genetic Spectrum of ATP6V1A Encephalopathy:
    A Disorder of Lysosomal Homeostasis.” <i>Brain</i>, vol. 145, no. 8, Oxford University
    Press, 2022, pp. 2687–703, doi:<a href="https://doi.org/10.1093/brain/awac145">10.1093/brain/awac145</a>.'
  short: R. Guerrini, D. Mei, M.K. Szigeti, S. Pepe, M.K. Koenig, G. Von Allmen, M.T.
    Cho, K. McDonald, J. Baker, V. Bhambhani, Z. Powis, L. Rodan, R. Nabbout, G. Barcia,
    J.A. Rosenfeld, C.A. Bacino, C. Mignot, L.H. Power, C.J. Harris, D. Marjanovic,
    R.S. Møller, T.B. Hammer, R. Keski Filppula, P. Vieira, C. Hildebrandt, S. Sacharow,
    L. Maragliano, F. Benfenati, K. Lachlan, A. Benneche, F. Petit, J.M. de Sainte
    Agathe, B. Hallinan, Y. Si, I.M. Wentzensen, F. Zou, V. Narayanan, N. Matsumoto,
    A. Boncristiano, G. la Marca, M. Kato, K. Anderson, C. Barba, L. Sturiale, D.
    Garozzo, R. Bei, L. Masuelli, V. Conti, G. Novarino, A. Fassio, Brain 145 (2022)
    2687–2703.
date_created: 2023-01-12T12:11:45Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2025-06-11T13:56:33Z
day: '01'
department:
- _id: GaNo
doi: 10.1093/brain/awac145
ec_funded: 1
external_id:
  isi:
  - '000807770000001'
  pmid:
  - '35675510'
intvolume: '       145'
isi: 1
issue: '8'
keyword:
- Neurology (clinical)
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/brain/awac145
month: '08'
oa: 1
oa_version: Published Version
page: 2687-2703
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Brain
publication_identifier:
  eissn:
  - 1460-2156
  issn:
  - 0006-8950
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Phenotypic and genetic spectrum of ATP6V1A encephalopathy: A disorder of lysosomal
  homeostasis'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 145
year: '2022'
...
---
_id: '12175'
abstract:
- lang: eng
  text: An automaton is history-deterministic (HD) if one can safely resolve its non-deterministic
    choices on the fly. In a recent paper, Henzinger, Lehtinen and Totzke studied
    this in the context of Timed Automata [9], where it was conjectured that the class
    of timed ω-languages recognised by HD-timed automata strictly extends that of
    deterministic ones. We provide a proof for this fact.
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093, the
  EPSRC project EP/V025848/1, and the EPSRC project EP/X017796/1.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sougata
  full_name: Bose, Sougata
  last_name: Bose
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Karoliina
  full_name: Lehtinen, Karoliina
  last_name: Lehtinen
- first_name: Sven
  full_name: Schewe, Sven
  last_name: Schewe
- first_name: Patrick
  full_name: Totzke, Patrick
  last_name: Totzke
citation:
  ama: 'Bose S, Henzinger TA, Lehtinen K, Schewe S, Totzke P. History-deterministic
    timed automata are not determinizable. In: <i>16th International Conference on
    Reachability Problems</i>. Vol 13608. Springer Nature; 2022:67-76. doi:<a href="https://doi.org/10.1007/978-3-031-19135-0_5">10.1007/978-3-031-19135-0_5</a>'
  apa: 'Bose, S., Henzinger, T. A., Lehtinen, K., Schewe, S., &#38; Totzke, P. (2022).
    History-deterministic timed automata are not determinizable. In <i>16th International
    Conference on Reachability Problems</i> (Vol. 13608, pp. 67–76). Kaiserslautern,
    Germany: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19135-0_5">https://doi.org/10.1007/978-3-031-19135-0_5</a>'
  chicago: Bose, Sougata, Thomas A Henzinger, Karoliina Lehtinen, Sven Schewe, and
    Patrick Totzke. “History-Deterministic Timed Automata Are Not Determinizable.”
    In <i>16th International Conference on Reachability Problems</i>, 13608:67–76.
    Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19135-0_5">https://doi.org/10.1007/978-3-031-19135-0_5</a>.
  ieee: S. Bose, T. A. Henzinger, K. Lehtinen, S. Schewe, and P. Totzke, “History-deterministic
    timed automata are not determinizable,” in <i>16th International Conference on
    Reachability Problems</i>, Kaiserslautern, Germany, 2022, vol. 13608, pp. 67–76.
  ista: 'Bose S, Henzinger TA, Lehtinen K, Schewe S, Totzke P. 2022. History-deterministic
    timed automata are not determinizable. 16th International Conference on Reachability
    Problems. RC: Reachability Problems, LNCS, vol. 13608, 67–76.'
  mla: Bose, Sougata, et al. “History-Deterministic Timed Automata Are Not Determinizable.”
    <i>16th International Conference on Reachability Problems</i>, vol. 13608, Springer
    Nature, 2022, pp. 67–76, doi:<a href="https://doi.org/10.1007/978-3-031-19135-0_5">10.1007/978-3-031-19135-0_5</a>.
  short: S. Bose, T.A. Henzinger, K. Lehtinen, S. Schewe, P. Totzke, in:, 16th International
    Conference on Reachability Problems, Springer Nature, 2022, pp. 67–76.
conference:
  end_date: 2022-10-21
  location: Kaiserslautern, Germany
  name: 'RC: Reachability Problems'
  start_date: 2022-10-17
date_created: 2023-01-12T12:11:57Z
date_published: 2022-10-12T00:00:00Z
date_updated: 2025-09-10T09:50:45Z
day: '12'
department:
- _id: ToHe
doi: 10.1007/978-3-031-19135-0_5
ec_funded: 1
external_id:
  isi:
  - '001333698300005'
intvolume: '     13608'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.science/hal-03849398/
month: '10'
oa: 1
oa_version: Preprint
page: 67-76
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 16th International Conference on Reachability Problems
publication_identifier:
  eisbn:
  - '9783031191350'
  eissn:
  - 1611-3349
  isbn:
  - '9783031191343'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: History-deterministic timed automata are not determinizable
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13608
year: '2022'
...
---
_id: '12177'
abstract:
- lang: eng
  text: Using elementary hyperbolic geometry, we give an explicit formula for the
    contraction constant of the skinning map over moduli spaces of relatively acylindrical
    hyperbolic manifolds.
acknowledgement: "The first author was partially supported by the National Science
  Foundation under Grant\r\nNo. DMS-1928930 while participating in a program hosted
  by the Mathematical Sciences Research Institute in Berkeley, California, during
  the Fall 2020 semester. The second author gratefully acknowledges funding by the
  Austrian Science Fund (FWF) through grants F65 and ESPRIT 208, by the European Research
  Council (ERC, grant No. 716117, awarded to Prof. Dr. Jan Maas), and by the Deutsche
  Forschungsgemeinschaft through the SPP 2265."
article_processing_charge: No
article_type: original
author:
- first_name: Tommaso
  full_name: Cremaschi, Tommaso
  last_name: Cremaschi
- first_name: Lorenzo
  full_name: Dello Schiavo, Lorenzo
  id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
  last_name: Dello Schiavo
  orcid: 0000-0002-9881-6870
citation:
  ama: Cremaschi T, Dello Schiavo L. Effective contraction of Skinning maps. <i>Proceedings
    of the American Mathematical Society, Series B</i>. 2022;9(43):445-459. doi:<a
    href="https://doi.org/10.1090/bproc/134">10.1090/bproc/134</a>
  apa: Cremaschi, T., &#38; Dello Schiavo, L. (2022). Effective contraction of Skinning
    maps. <i>Proceedings of the American Mathematical Society, Series B</i>. American
    Mathematical Society. <a href="https://doi.org/10.1090/bproc/134">https://doi.org/10.1090/bproc/134</a>
  chicago: Cremaschi, Tommaso, and Lorenzo Dello Schiavo. “Effective Contraction of
    Skinning Maps.” <i>Proceedings of the American Mathematical Society, Series B</i>.
    American Mathematical Society, 2022. <a href="https://doi.org/10.1090/bproc/134">https://doi.org/10.1090/bproc/134</a>.
  ieee: T. Cremaschi and L. Dello Schiavo, “Effective contraction of Skinning maps,”
    <i>Proceedings of the American Mathematical Society, Series B</i>, vol. 9, no.
    43. American Mathematical Society, pp. 445–459, 2022.
  ista: Cremaschi T, Dello Schiavo L. 2022. Effective contraction of Skinning maps.
    Proceedings of the American Mathematical Society, Series B. 9(43), 445–459.
  mla: Cremaschi, Tommaso, and Lorenzo Dello Schiavo. “Effective Contraction of Skinning
    Maps.” <i>Proceedings of the American Mathematical Society, Series B</i>, vol.
    9, no. 43, American Mathematical Society, 2022, pp. 445–59, doi:<a href="https://doi.org/10.1090/bproc/134">10.1090/bproc/134</a>.
  short: T. Cremaschi, L. Dello Schiavo, Proceedings of the American Mathematical
    Society, Series B 9 (2022) 445–459.
corr_author: '1'
date_created: 2023-01-12T12:12:17Z
date_published: 2022-11-02T00:00:00Z
date_updated: 2025-04-14T07:27:48Z
day: '02'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1090/bproc/134
ec_funded: 1
file:
- access_level: open_access
  checksum: cb4a79937c1f60d4c329a10ee797f0d2
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-26T13:02:07Z
  date_updated: 2023-01-26T13:02:07Z
  file_id: '12404'
  file_name: 2022_ProceedingsAMS_Cremaschi.pdf
  file_size: 326471
  relation: main_file
  success: 1
file_date_updated: 2023-01-26T13:02:07Z
has_accepted_license: '1'
intvolume: '         9'
issue: '43'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 445-459
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
publication: Proceedings of the American Mathematical Society, Series B
publication_identifier:
  issn:
  - 2330-1511
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Effective contraction of Skinning maps
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2022'
...
---
_id: '12179'
abstract:
- lang: eng
  text: We derive an accurate lower tail estimate on the lowest singular value σ1(X−z)
    of a real Gaussian (Ginibre) random matrix X shifted by a complex parameter z.
    Such shift effectively changes the upper tail behavior of the condition number
    κ(X−z) from the slower (κ(X−z)≥t)≲1/t decay typical for real Ginibre matrices
    to the faster 1/t2 decay seen for complex Ginibre matrices as long as z is away
    from the real axis. This sharpens and resolves a recent conjecture in [J. Banks
    et al., https://arxiv.org/abs/2005.08930, 2020] on the regularizing effect of
    the real Ginibre ensemble with a genuinely complex shift. As a consequence we
    obtain an improved upper bound on the eigenvalue condition numbers (known also
    as the eigenvector overlaps) for real Ginibre matrices. The main technical tool
    is a rigorous supersymmetric analysis from our earlier work [Probab. Math. Phys.,
    1 (2020), pp. 101--146].
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. On the condition number of the shifted real
    Ginibre ensemble. <i>SIAM Journal on Matrix Analysis and Applications</i>. 2022;43(3):1469-1487.
    doi:<a href="https://doi.org/10.1137/21m1424408">10.1137/21m1424408</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2022). On the condition number
    of the shifted real Ginibre ensemble. <i>SIAM Journal on Matrix Analysis and Applications</i>.
    Society for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/21m1424408">https://doi.org/10.1137/21m1424408</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “On the Condition
    Number of the Shifted Real Ginibre Ensemble.” <i>SIAM Journal on Matrix Analysis
    and Applications</i>. Society for Industrial and Applied Mathematics, 2022. <a
    href="https://doi.org/10.1137/21m1424408">https://doi.org/10.1137/21m1424408</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “On the condition number of the
    shifted real Ginibre ensemble,” <i>SIAM Journal on Matrix Analysis and Applications</i>,
    vol. 43, no. 3. Society for Industrial and Applied Mathematics, pp. 1469–1487,
    2022.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2022. On the condition number of the shifted
    real Ginibre ensemble. SIAM Journal on Matrix Analysis and Applications. 43(3),
    1469–1487.
  mla: Cipolloni, Giorgio, et al. “On the Condition Number of the Shifted Real Ginibre
    Ensemble.” <i>SIAM Journal on Matrix Analysis and Applications</i>, vol. 43, no.
    3, Society for Industrial and Applied Mathematics, 2022, pp. 1469–87, doi:<a href="https://doi.org/10.1137/21m1424408">10.1137/21m1424408</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, SIAM Journal on Matrix Analysis and
    Applications 43 (2022) 1469–1487.
corr_author: '1'
date_created: 2023-01-12T12:12:38Z
date_published: 2022-07-01T00:00:00Z
date_updated: 2025-09-10T09:51:27Z
day: '01'
department:
- _id: LaEr
doi: 10.1137/21m1424408
external_id:
  arxiv:
  - '2105.13719'
  isi:
  - '001125796400002'
intvolume: '        43'
isi: 1
issue: '3'
keyword:
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2105.13719
month: '07'
oa: 1
oa_version: Preprint
page: 1469-1487
publication: SIAM Journal on Matrix Analysis and Applications
publication_identifier:
  eissn:
  - 1095-7162
  issn:
  - 0895-4798
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the condition number of the shifted real Ginibre ensemble
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 43
year: '2022'
...
