--- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '12311' abstract: - lang: eng text: In this note, we prove a formula for the cancellation exponent kv,n between division polynomials ψn and ϕn associated with a sequence {nP}n∈N of points on an elliptic curve E defined over a discrete valuation field K. The formula greatly generalizes the previously known special cases and treats also the case of non-standard Kodaira types for non-perfect residue fields. acknowledgement: Silverman, and Paul Voutier for the comments on the earlier version of this paper. The first author acknowledges the support by Dioscuri programme initiated by the Max Planck Society, jointly managed with the National Science Centre (Poland), and mutually funded by the Polish Ministry of Science and Higher Education and the German Federal Ministry of Education and Research. The second author has been supported by MIUR (Italy) through PRIN 2017 ‘Geometric, algebraic and analytic methods in arithmetic’ and has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413. article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Bartosz full_name: Naskręcki, Bartosz last_name: Naskręcki - first_name: Matteo full_name: Verzobio, Matteo id: 7aa8f170-131e-11ed-88e1-a9efd01027cb last_name: Verzobio orcid: 0000-0002-0854-0306 citation: ama: 'Naskręcki B, Verzobio M. Common valuations of division polynomials. Proceedings of the Royal Society of Edinburgh Section A: Mathematics. 2025;155(5):1646-1660. doi:10.1017/prm.2024.7' apa: 'Naskręcki, B., & Verzobio, M. (2025). Common valuations of division polynomials. Proceedings of the Royal Society of Edinburgh Section A: Mathematics. Cambridge University Press. https://doi.org/10.1017/prm.2024.7' chicago: 'Naskręcki, Bartosz, and Matteo Verzobio. “Common Valuations of Division Polynomials.” Proceedings of the Royal Society of Edinburgh Section A: Mathematics. Cambridge University Press, 2025. https://doi.org/10.1017/prm.2024.7.' ieee: 'B. Naskręcki and M. Verzobio, “Common valuations of division polynomials,” Proceedings of the Royal Society of Edinburgh Section A: Mathematics, vol. 155, no. 5. Cambridge University Press, pp. 1646–1660, 2025.' ista: 'Naskręcki B, Verzobio M. 2025. Common valuations of division polynomials. Proceedings of the Royal Society of Edinburgh Section A: Mathematics. 155(5), 1646–1660.' mla: 'Naskręcki, Bartosz, and Matteo Verzobio. “Common Valuations of Division Polynomials.” Proceedings of the Royal Society of Edinburgh Section A: Mathematics, vol. 155, no. 5, Cambridge University Press, 2025, pp. 1646–60, doi:10.1017/prm.2024.7.' short: 'B. Naskręcki, M. Verzobio, Proceedings of the Royal Society of Edinburgh Section A: Mathematics 155 (2025) 1646–1660.' corr_author: '1' date_created: 2023-01-16T11:45:22Z date_published: 2025-10-01T00:00:00Z date_updated: 2025-12-30T06:46:17Z day: '01' ddc: - '510' department: - _id: TiBr doi: 10.1017/prm.2024.7 ec_funded: 1 external_id: arxiv: - '2203.02015' isi: - '001174907100001' file: - access_level: open_access checksum: c5ec6e29aca2fb4533cb95fac409a0b2 content_type: application/pdf creator: dernst date_created: 2025-12-30T06:45:47Z date_updated: 2025-12-30T06:45:47Z file_id: '20878' file_name: 2025_ProceedingsRoyalSocEdinburghA_Naskrecki.pdf file_size: 477624 relation: main_file success: 1 file_date_updated: 2025-12-30T06:45:47Z has_accepted_license: '1' intvolume: ' 155' isi: 1 issue: '5' keyword: - Elliptic curves - Néron models - division polynomials - height functions - discrete valuation rings language: - iso: eng month: '10' oa: 1 oa_version: Published Version page: 1646-1660 project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: 'Proceedings of the Royal Society of Edinburgh Section A: Mathematics' publication_identifier: eissn: - 1473-7124 issn: - 0308-2105 publication_status: published publisher: Cambridge University Press quality_controlled: '1' scopus_import: '1' status: public title: Common valuations of division polynomials tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 155 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '12662' abstract: - lang: eng text: 'Modern machine learning tasks often require considering not just one but multiple objectives. For example, besides the prediction quality, this could be the efficiency, robustness or fairness of the learned models, or any of their combinations. Multi-objective learning offers a natural framework for handling such problems without having to commit to early trade-offs. Surprisingly, statistical learning theory so far offers almost no insight into the generalization properties of multi-objective learning. In this work, we make first steps to fill this gap: We establish foundational generalization bounds for the multi-objective setting as well as generalization and excess bounds for learning with scalarizations. We also provide the first theoretical analysis of the relation between the Pareto-optimal sets of the true objectives and the Pareto-optimal sets of their empirical approximations from training data. In particular, we show a surprising asymmetry: All Pareto-optimal solutions can be approximated by empirically Pareto-optimal ones, but not vice versa.' acknowledgement: Open access funding provided by Institute of Science and Technology (IST Austria). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Peter full_name: Súkeník, Peter id: d64d6a8d-eb8e-11eb-b029-96fd216dec3c last_name: Súkeník - first_name: Christoph full_name: Lampert, Christoph id: 40C20FD2-F248-11E8-B48F-1D18A9856A87 last_name: Lampert orcid: 0000-0001-8622-7887 citation: ama: Súkeník P, Lampert C. Generalization in multi-objective machine learning. Neural Computing and Applications. 2025;37:24669–24683. doi:10.1007/s00521-024-10616-1 apa: Súkeník, P., & Lampert, C. (2025). Generalization in multi-objective machine learning. Neural Computing and Applications. Springer Nature. https://doi.org/10.1007/s00521-024-10616-1 chicago: Súkeník, Peter, and Christoph Lampert. “Generalization in Multi-Objective Machine Learning.” Neural Computing and Applications. Springer Nature, 2025. https://doi.org/10.1007/s00521-024-10616-1. ieee: P. Súkeník and C. Lampert, “Generalization in multi-objective machine learning,” Neural Computing and Applications, vol. 37. Springer Nature, pp. 24669–24683, 2025. ista: Súkeník P, Lampert C. 2025. Generalization in multi-objective machine learning. Neural Computing and Applications. 37, 24669–24683. mla: Súkeník, Peter, and Christoph Lampert. “Generalization in Multi-Objective Machine Learning.” Neural Computing and Applications, vol. 37, Springer Nature, 2025, pp. 24669–24683, doi:10.1007/s00521-024-10616-1. short: P. Súkeník, C. Lampert, Neural Computing and Applications 37 (2025) 24669–24683. corr_author: '1' date_created: 2023-02-20T08:23:06Z date_published: 2025-10-01T00:00:00Z date_updated: 2025-12-30T06:39:56Z day: '01' ddc: - '004' department: - _id: ChLa doi: 10.1007/s00521-024-10616-1 external_id: arxiv: - '2208.13499' file: - access_level: open_access checksum: 61ad4591aee16b1e02daf6c164321a42 content_type: application/pdf creator: dernst date_created: 2025-12-30T06:39:11Z date_updated: 2025-12-30T06:39:11Z file_id: '20877' file_name: 2025_NeuralCompApplic_Sukenik.pdf file_size: 500213 relation: main_file success: 1 file_date_updated: 2025-12-30T06:39:11Z has_accepted_license: '1' intvolume: ' 37' language: - iso: eng month: '10' oa: 1 oa_version: Published Version page: 24669–24683 publication: Neural Computing and Applications publication_identifier: eissn: - 1433-3058 issn: - 0941-0643 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Generalization in multi-objective machine learning tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 37 year: '2025' ... --- OA_place: publisher OA_type: gold _id: '20820' abstract: - lang: eng text: 'The high computational costs of large language models (LLMs) have led to a flurry of research on LLM compression, via methods such as quantization, sparsification, or structured pruning. A new frontier in this area is given by dynamic, non-uniform compression methods, which adjust the compression levels (e.g., sparsity) per-block or even per-layer in order to minimize accuracy loss, while guaranteeing a global compression threshold. Yet, current methods rely on estimating the "importance" of a given layer, implicitly assuming that layers contribute independently to the overall compression error. We begin from the motivating observation that this independence assumption does not generally hold for LLM compression: pruning a model further may even significantly recover performance. To address this, we propose EvoPress, a novel evolutionary framework for dynamic LLM compression. By formulating dynamic compression as a general optimization problem, EvoPress identifies optimal compression profiles in a highly efficient manner, and generalizes across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art performance for dynamic compression of Llama, Mistral, and Phi models, setting new benchmarks for structural pruning (block/layer dropping), unstructured sparsity, and quantization with dynamic bitwidths.' alternative_title: - PMLR article_processing_charge: No arxiv: 1 author: - first_name: Oliver full_name: Sieberling, Oliver last_name: Sieberling - first_name: Denis full_name: Kuznedelev, Denis last_name: Kuznedelev - first_name: Eldar full_name: Kurtic, Eldar id: 47beb3a5-07b5-11eb-9b87-b108ec578218 last_name: Kurtic - first_name: Dan-Adrian full_name: Alistarh, Dan-Adrian id: 4A899BFC-F248-11E8-B48F-1D18A9856A87 last_name: Alistarh orcid: 0000-0003-3650-940X citation: ama: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic model compression via evolutionary search. In: 42nd International Conference on Machine Learning. Vol 267. ML Research Press; 2025:55556-55590.' apa: 'Sieberling, O., Kuznedelev, D., Kurtic, E., & Alistarh, D.-A. (2025). EvoPress: Accurate dynamic model compression via evolutionary search. In 42nd International Conference on Machine Learning (Vol. 267, pp. 55556–55590). Vancouver, Canada: ML Research Press.' chicago: 'Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In 42nd International Conference on Machine Learning, 267:55556–90. ML Research Press, 2025.' ieee: 'O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate dynamic model compression via evolutionary search,” in 42nd International Conference on Machine Learning, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.' ista: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate dynamic model compression via evolutionary search. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 55556–55590.' mla: 'Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” 42nd International Conference on Machine Learning, vol. 267, ML Research Press, 2025, pp. 55556–90.' short: O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590. conference: end_date: 2025-07-19 location: Vancouver, Canada name: 'ICML: International Conference on Machine Learning' start_date: 2025-07-13 corr_author: '1' date_created: 2025-12-14T23:02:05Z date_published: 2025-05-01T00:00:00Z date_updated: 2025-12-16T12:34:32Z day: '01' ddc: - '000' department: - _id: DaAl external_id: arxiv: - '2410.14649' file: - access_level: open_access checksum: 1d744fbaeb199b08e8b6f48bc0dd047e content_type: application/pdf creator: dernst date_created: 2025-12-16T12:32:40Z date_updated: 2025-12-16T12:32:40Z file_id: '20828' file_name: 2025_ICML_Sieberling.pdf file_size: 908379 relation: main_file success: 1 file_date_updated: 2025-12-16T12:32:40Z has_accepted_license: '1' intvolume: ' 267' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: 55556-55590 publication: 42nd International Conference on Machine Learning publication_identifier: eissn: - 2640-3498 publication_status: published publisher: ML Research Press quality_controlled: '1' scopus_import: '1' status: public title: 'EvoPress: Accurate dynamic model compression via evolutionary search' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 267 year: '2025' ... --- OA_place: publisher OA_type: gold _id: '20821' abstract: - lang: eng text: Modern deep neural networks exhibit heterogeneity across numerous layers of various types such as residuals, multi-head attention, etc., due to varying structures (dimensions, activation functions, etc.), distinct representation characteristics, which impact predictions. We develop a general layer-wise quantization framework with tight variance and code-length bounds, adapting to the heterogeneities over the course of training. We then apply a new layer-wise quantization technique within distributed variational inequalities (VIs), proposing a novel Quantized Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which achieves competitive convergence rates for monotone VIs. We empirically show that QODA achieves up to a 150% speedup over the baselines in end-to-end training time for training Wasserstein GAN on 12+GPUs. acknowledgement: "This work was supported by Hasler Foundation Program: Hasler Responsible AI (project number 21043). The research was also sponsored by the Army Research Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011. We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS) for providing computing resources. Dan Alistarh and Ilia Markov were supported in part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian Centre for knowledge-driven machine learning under\r\nproject number 332645 - and its Centre for Research-based Innovation funding scheme (Visual Intelligence under grant no. 309439)." alternative_title: - PMLR article_processing_charge: No arxiv: 1 author: - first_name: Anh Duc full_name: Nguyen, Anh Duc last_name: Nguyen - first_name: Ilia full_name: Markov, Ilia id: D0CF4148-C985-11E9-8066-0BDEE5697425 last_name: Markov - first_name: Frank Zhengqing full_name: Wu, Frank Zhengqing last_name: Wu - first_name: Ali full_name: Ramezani-Kebrya, Ali last_name: Ramezani-Kebrya - first_name: Kimon full_name: Antonakopoulos, Kimon last_name: Antonakopoulos - first_name: Dan-Adrian full_name: Alistarh, Dan-Adrian id: 4A899BFC-F248-11E8-B48F-1D18A9856A87 last_name: Alistarh orcid: 0000-0003-3650-940X - first_name: Volkan full_name: Cevher, Volkan last_name: Cevher citation: ama: 'Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic dual averaging. In: 42nd International Conference on Machine Learning. Vol 267. ML Research Press; 2025:46026-46072.' apa: 'Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos, K., Alistarh, D.-A., & Cevher, V. (2025). Layer-wise quantization for quantized optimistic dual averaging. In 42nd International Conference on Machine Learning (Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press.' chicago: Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya, Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” In 42nd International Conference on Machine Learning, 267:46026–72. ML Research Press, 2025. ieee: A. D. Nguyen et al., “Layer-wise quantization for quantized optimistic dual averaging,” in 42nd International Conference on Machine Learning, Vancouver, Canada, 2025, vol. 267, pp. 46026–46072. ista: 'Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 46026–46072.' mla: Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” 42nd International Conference on Machine Learning, vol. 267, ML Research Press, 2025, pp. 46026–72. short: A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A. Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 46026–46072. conference: end_date: 2025-07-19 location: Vancouver, Canada name: 'ICML: International Conference on Machine Learning' start_date: 2025-07-13 date_created: 2025-12-14T23:02:06Z date_published: 2025-05-01T00:00:00Z date_updated: 2025-12-16T12:46:54Z day: '01' ddc: - '000' department: - _id: DaAl external_id: arxiv: - '2505.14371' file: - access_level: open_access checksum: a7edf0e4304171a3e035842b3aab1704 content_type: application/pdf creator: dernst date_created: 2025-12-16T12:45:41Z date_updated: 2025-12-16T12:45:41Z file_id: '20830' file_name: 2025_ICML_Nguyen.pdf file_size: 756213 relation: main_file success: 1 file_date_updated: 2025-12-16T12:45:41Z has_accepted_license: '1' intvolume: ' 267' language: - iso: eng month: '05' oa: 1 oa_version: Published Version page: 46026-46072 project: - _id: 8e35c14b-16d5-11f0-9cad-a3fc35339161 grant_number: '101158077' name: 'FastML: Efficient and Cost-Effective Distributed Machine Learning' publication: 42nd International Conference on Machine Learning publication_identifier: eissn: - 2640-3498 publication_status: published publisher: ML Research Press quality_controlled: '1' scopus_import: '1' status: public title: Layer-wise quantization for quantized optimistic dual averaging tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 267 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '20839' abstract: - lang: eng text: For every couple of Hausdorff functions ψ and φ verifying some mild assumptions, there exists a compact subset K of the Baire space such that the φ-Hausdorff measure and the ψ-packing measure on K are both finite and positive. Such examples are then embedded in any infinite dimensional Banach space to answer positively a question of Fan on the existence of metric spaces with arbitrary scales. article_processing_charge: Yes article_type: original author: - first_name: Mathieu full_name: Helfter, Mathieu id: 7d296fbe-e2c6-11ee-84d3-d5c2945f9a57 last_name: Helfter citation: ama: Helfter M. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. Journal of Fractal Geometry. 2025. doi:10.4171/jfg/177 apa: Helfter, M. (2025). Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. Journal of Fractal Geometry. EMS Press. https://doi.org/10.4171/jfg/177 chicago: Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” Journal of Fractal Geometry. EMS Press, 2025. https://doi.org/10.4171/jfg/177. ieee: M. Helfter, “Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces,” Journal of Fractal Geometry. EMS Press, 2025. ista: Helfter M. 2025. Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces. Journal of Fractal Geometry. mla: Helfter, Mathieu. “Sets with Arbitrary Hausdorff and Packing Scales in Infinite Dimensional Banach Spaces.” Journal of Fractal Geometry, EMS Press, 2025, doi:10.4171/jfg/177. short: M. Helfter, Journal of Fractal Geometry (2025). corr_author: '1' date_created: 2025-12-19T10:15:37Z date_published: 2025-11-07T00:00:00Z date_updated: 2026-06-18T18:26:33Z day: '07' ddc: - '500' department: - _id: VaKa doi: 10.4171/jfg/177 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.4171/jfg/177 month: '11' oa: 1 oa_version: Published Version publication: Journal of Fractal Geometry publication_identifier: eissn: - 2308-1317 issn: - 2308-1309 publication_status: epub_ahead publisher: EMS Press quality_controlled: '1' scopus_import: '1' status: public title: Sets with arbitrary Hausdorff and packing scales in infinite dimensional Banach spaces type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2025' ... --- _id: '20842' abstract: - lang: eng text: Probing the possibility of entanglement generation through gravity offers a path to tackle the question of whether gravitational fields possess a quantum mechanical nature. A potential realization necessitates systems with low-frequency dynamics at an optimal mass scale, for which the microgram-to-milligram range is a strong contender. Here, after refining a figure-of-merit for the problem, we present a 1-milligram torsional pendulum operating at 18 Hz. We demonstrate laser cooling its motion from room temperature to 240~microkelvins, surpassing by over 20-fold the coldest motions attained for oscillators ranging from micrograms to kilograms. We quantify and contrast the utility of the current approach with other platforms. The achieved performance and large improvement potential highlight milligram-scale torsional pendulums as a powerful platform for precision measurements relevant to future studies at the quantum-gravity interface. article_processing_charge: No author: - first_name: Sofya full_name: Agafonova, Sofya id: 09501ff6-dca7-11ea-a8ae-b3e0b9166e80 last_name: Agafonova orcid: 0000-0003-0582-2946 citation: ama: 'Agafonova S. Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” 2025. doi:10.15479/AT-ISTA-20842' apa: 'Agafonova, S. (2025). Research Data for: “One-milligram torsional pendulum toward experiments at the quantum-gravity interface.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-20842' chicago: 'Agafonova, Sofia. “Research Data for: ‘One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.’” Institute of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-20842.' ieee: 'S. Agafonova, “Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface.’” Institute of Science and Technology Austria, 2025.' ista: 'Agafonova S. 2025. Research Data for: ‘One-milligram torsional pendulum toward experiments at the quantum-gravity interface’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-20842.' mla: 'Agafonova, Sofia. Research Data for: “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.” Institute of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-20842.' short: S. Agafonova, (2025). contributor: - first_name: Pere last_name: Rosello - first_name: Manuel last_name: Mekonnen - contributor_type: supervisor first_name: Onur id: 4C02D85E-F248-11E8-B48F-1D18A9856A87 last_name: Hosten orcid: 0000-0002-2031-204X corr_author: '1' date_created: 2025-12-21T14:23:50Z date_published: 2025-12-22T00:00:00Z date_updated: 2026-06-10T08:36:07Z day: '22' department: - _id: GradSch - _id: OnHo doi: 10.15479/AT-ISTA-20842 file: - access_level: open_access checksum: 7af34e4226a00cdcb7f154272050e217 content_type: application/x-zip-compressed creator: sagafono date_created: 2025-12-22T13:45:30Z date_updated: 2025-12-22T13:45:30Z file_id: '20854' file_name: AllData.zip file_size: 146656591 relation: main_file success: 1 - access_level: open_access checksum: 71806a2ef9fb26ad7b78e04c6754ee4e content_type: application/x-zip-compressed creator: sagafono date_created: 2025-12-22T13:45:33Z date_updated: 2025-12-22T13:45:33Z file_id: '20855' file_name: SourceData.zip file_size: 93470129 relation: main_file success: 1 - access_level: open_access checksum: 08facd1b4a102f83e4d99d48a85b258d content_type: text/plain creator: sagafono date_created: 2025-12-22T13:51:09Z date_updated: 2025-12-22T13:51:09Z file_id: '20856' file_name: readme.txt file_size: 461 relation: main_file success: 1 file_date_updated: 2025-12-22T13:51:09Z has_accepted_license: '1' month: '12' oa: 1 oa_version: Published Version project: - _id: bdb2a702-d553-11ed-ba76-f12e3e5a3bc6 grant_number: '101087907' name: 'A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics' publisher: Institute of Science and Technology Austria related_material: record: - id: '20840' relation: used_in_publication status: public status: public title: 'Research Data for: ''One-milligram torsional pendulum toward experiments at the quantum-gravity interface''' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: research_data user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d year: '2025' ... --- OA_place: repository OA_type: green _id: '20844' abstract: - lang: eng text: "We introduce and construct a new proof system called Non-interactive Arguments of Knowledge or Space (NArKoS), where a space-bounded prover can convince a verifier they know a secret, while having access to sufficient space allows one to forge indistinguishable proofs without the secret.\r\nAn application of NArKoS are space-deniable proofs, which are proofs of knowledge (say for authentication in access control) that are sound when executed by a lightweight device like a smart-card or an RFID chip that cannot have much storage, but are deniable (in the strong sense of online deniability) as the verifier, like a card reader, can efficiently forge such proofs.\r\nWe construct NArKoS in the random oracle model using an OR-proof combining a sigma protocol (for the proof of knowledge of the secret) with a new proof system called simulatable Proof of Transient Space (simPoTS). We give two different constructions of simPoTS, one based on labelling graphs with high pebbling complexity, a technique used in the construction of memory-hard functions and proofs of space, and a more practical construction based on the verifiable space-hard functions from TCC’24 where a prover must compute a root of a sparse polynomial. In both cases, the main challenge is making the proofs efficiently simulatable." acknowledgement: "Jesko Dujmovic: Funded by the European Union (ERC, LACONIC, 101041207). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them.\r\nChristoph U. Günther and Krzysztof Pietrzak: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission." alternative_title: - LNCS article_processing_charge: No author: - first_name: Jesko full_name: Dujmovic, Jesko last_name: Dujmovic - first_name: Christoph Ullrich full_name: Günther, Christoph Ullrich id: ec98511c-eb8e-11eb-b029-edd25d7271a1 last_name: Günther - first_name: Krzysztof Z full_name: Pietrzak, Krzysztof Z id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87 last_name: Pietrzak orcid: 0000-0002-9139-1654 citation: ama: 'Dujmovic J, Günther CU, Pietrzak KZ. Space-deniable proofs. In: 23rd International Conference on Theory of Cryptography. Vol 16271. Springer Nature; 2025:171-202. doi:10.1007/978-3-032-12290-2_6' apa: 'Dujmovic, J., Günther, C. U., & Pietrzak, K. Z. (2025). Space-deniable proofs. In 23rd International Conference on Theory of Cryptography (Vol. 16271, pp. 171–202). Aarhus, Denmark: Springer Nature. https://doi.org/10.1007/978-3-032-12290-2_6' chicago: Dujmovic, Jesko, Christoph Ullrich Günther, and Krzysztof Z Pietrzak. “Space-Deniable Proofs.” In 23rd International Conference on Theory of Cryptography, 16271:171–202. Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12290-2_6. ieee: J. Dujmovic, C. U. Günther, and K. Z. Pietrzak, “Space-deniable proofs,” in 23rd International Conference on Theory of Cryptography, Aarhus, Denmark, 2025, vol. 16271, pp. 171–202. ista: 'Dujmovic J, Günther CU, Pietrzak KZ. 2025. Space-deniable proofs. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 171–202.' mla: Dujmovic, Jesko, et al. “Space-Deniable Proofs.” 23rd International Conference on Theory of Cryptography, vol. 16271, Springer Nature, 2025, pp. 171–202, doi:10.1007/978-3-032-12290-2_6. short: J. Dujmovic, C.U. Günther, K.Z. Pietrzak, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 171–202. conference: end_date: 2025-12-05 location: Aarhus, Denmark name: 'TCC: Theory of Cryptography' start_date: 2025-12-01 corr_author: '1' date_created: 2025-12-21T23:01:33Z date_published: 2025-12-05T00:00:00Z date_updated: 2025-12-29T11:44:16Z day: '05' department: - _id: KrPi doi: 10.1007/978-3-032-12290-2_6 intvolume: ' 16271' language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2025/1723 month: '12' oa: 1 oa_version: Preprint page: 171-202 project: - _id: 34a34d57-11ca-11ed-8bc3-a2688a8724e1 grant_number: F8509 name: Security and Privacy by Design for Complex Systems publication: 23rd International Conference on Theory of Cryptography publication_identifier: eissn: - 1611-3349 isbn: - '9783032122896' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Space-deniable proofs type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 16271 year: '2025' ... --- OA_place: repository OA_type: green _id: '20845' abstract: - lang: eng text: "We develop new attacks against the Evasive LWE family of assumptions, in both the public and private-coin regime. To the best of our knowledge, ours are the first attacks against Evasive LWE in the public-coin regime, for any instantiation from the family. Our attacks are summarized below.\r\n\r\nPublic-Coin Attacks.\r\n1.The recent work by Hseih, Lin and Luo [17] constructed the first Attribute Based Encryption (ABE) for unbounded depth circuits by relying on the “circular” evasive LWE assumption. This assumption has been popularly considered as a safe, public-coin instance of Evasive LWE in contrast to its “private-coin” cousins (for instance, see [10, 11]).\r\nWe provide the first attack against this assumption, challenging the widely held belief that this is a public-coin assumption.\r\n2. We demonstrate a counter-example against vanilla public-coin evasive LWE by Wee [26] in an unnatural parameter regime. Our attack crucially relies on the error in the pre-condition being larger than the error in the post-condition, necessitating a refinement of the assumption.\r\n\r\nPrivate-Coin Attacks.\r\n1. The recent work by Agrawal, Kumari and Yamada [2] constructed the first functional encryption scheme for pseudorandom functionalities (PRFE) and extended this to obfuscation for pseudorandom functionalities (PRIO) [4] by relying on private-coin evasive LWE. We provide a new attack against the assumption stated in the first posting of their work (subsequently refined to avoid these attacks).\r\n2. The recent work by Branco et al. [8] (concurrently to [4]) provides a construction of obfuscation for pseudorandom functionalities by relying on private-coin evasive LWE. We provide a new attack against their stated assumption.\r\n3. Branco et al. [8] showed that there exist contrived, “self-referential” classes of pseudorandom functionalities for which pseudorandom obfuscation cannot exist. We extend their techniques to develop an analogous result for pseudorandom functional encryption.\r\n\r\nWhile Evasive LWE was developed to specifically avoid “zeroizing attacks”, our work shows that in certain settings, such attacks can still apply." acknowledgement: "We thank Rachel Lin for expressing concern about the applicability of “HJL-style” attacks [15] on the construction in [2] during a talk by the first author about [2]. This was the starting point of the investigation that led us to develop the attack in [5, Sec 4.1]. The first author also thanks Hoeteck Wee for sharing his rationale for introducing evasive LWE.\r\nThe first author is supported by the CyStar center of excellence, the VHAR faculty chair, and the C3iHub fellowship. The third author thanks Cystar, IIT Madras, for supporting a visit to IIT Madras during which the collaboration was initiated. The 4th author is partly supported by JST CREST Grant Number JPMJCR22M1." alternative_title: - LNCS article_processing_charge: No author: - first_name: Shweta full_name: Agrawal, Shweta last_name: Agrawal - first_name: Anuja full_name: Modi, Anuja last_name: Modi - first_name: Anshu full_name: Yadav, Anshu id: dc8f1524-403e-11ee-bf07-9649ad996e21 last_name: Yadav - first_name: Shota full_name: Yamada, Shota last_name: Yamada citation: ama: 'Agrawal S, Modi A, Yadav A, Yamada S. Zeroizing attacks against evasive and circular evasive LWE. In: 23rd International Conference on Theory of Cryptography. Vol 16269. Springer Nature; 2025:259-290. doi:10.1007/978-3-032-12293-3_9' apa: 'Agrawal, S., Modi, A., Yadav, A., & Yamada, S. (2025). Zeroizing attacks against evasive and circular evasive LWE. In 23rd International Conference on Theory of Cryptography (Vol. 16269, pp. 259–290). Aarhus, Denmark: Springer Nature. https://doi.org/10.1007/978-3-032-12293-3_9' chicago: Agrawal, Shweta, Anuja Modi, Anshu Yadav, and Shota Yamada. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” In 23rd International Conference on Theory of Cryptography, 16269:259–90. Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12293-3_9. ieee: S. Agrawal, A. Modi, A. Yadav, and S. Yamada, “Zeroizing attacks against evasive and circular evasive LWE,” in 23rd International Conference on Theory of Cryptography, Aarhus, Denmark, 2025, vol. 16269, pp. 259–290. ista: 'Agrawal S, Modi A, Yadav A, Yamada S. 2025. Zeroizing attacks against evasive and circular evasive LWE. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16269, 259–290.' mla: Agrawal, Shweta, et al. “Zeroizing Attacks against Evasive and Circular Evasive LWE.” 23rd International Conference on Theory of Cryptography, vol. 16269, Springer Nature, 2025, pp. 259–90, doi:10.1007/978-3-032-12293-3_9. short: S. Agrawal, A. Modi, A. Yadav, S. Yamada, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 259–290. conference: end_date: 2025-12-05 location: Aarhus, Denmark name: 'TCC: Theory of Cryptography' start_date: 2025-12-01 date_created: 2025-12-21T23:01:33Z date_published: 2025-12-05T00:00:00Z date_updated: 2025-12-29T11:51:13Z day: '05' department: - _id: KrPi doi: 10.1007/978-3-032-12293-3_9 intvolume: ' 16269' language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2025/375 month: '12' oa: 1 oa_version: Preprint page: 259-290 publication: 23rd International Conference on Theory of Cryptography publication_identifier: eissn: - 1611-3349 isbn: - '9783032122926' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Zeroizing attacks against evasive and circular evasive LWE type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 16269 year: '2025' ... --- OA_place: repository OA_type: green _id: '20846' abstract: - lang: eng text: "CVRFs are PRFs that unify the properties of verifiable and constrained PRFs. Since they were introduced concurrently by Fuchsbauer and Chandran-Raghuraman-Vinayagamurthy in 2014, it has been an open problem to construct CVRFs without using heavy machinery such as multilinear maps, obfuscation or functional encryption.\r\nWe solve this problem by constructing a prefix-constrained verifiable PRF that does not rely on the aforementioned assumptions. Essentially, our construction is a verifiable version of the Goldreich-Goldwasser-Micali PRF. To achieve verifiability we leverage degree-2 algebraic PRGs and bilinear groups. In short, proofs consist of intermediate values of the Goldreich-Goldwasser-Micali PRF raised to the exponents of group elements. These outputs can be verified using pairings since the underlying PRG is of degree 2.\r\nWe prove the selective security of our construction under the Decisional Square Diffie-Hellman (DSDH) assumption and a new assumption, which we dub recursive Decisional Diffie-Hellman (recursive DDH).\r\nWe prove the soundness of recursive DDH in the generic group model assuming the hardness of the Multivariate Quadratic (MQ) problem and a new variant thereof, which we call MQ+.\r\nLast, in terms of applications, we observe that our CVRF is also an exponent (C)VRF in the plain model. Exponent VRFs were recently introduced by Boneh et al. (Eurocrypt’25) with various applications to threshold cryptography in mind. In addition to that, we give further applications for prefix-CVRFs in the blockchain setting, namely, stake-pooling and compressible randomness beacons." acknowledgement: "We thank Jonas Steinbach and Gertjan De Mulder for helpful discussions on BIP 32, Dennis Hofheinz and Julia Kastner for helpful discussions on early prototypes of our CVRF, and Klaus Kraßnitzer for running pairing benchmarks on his MacBook Pro.\r\nChristoph U. Günther: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission." alternative_title: - LNCS article_processing_charge: No author: - first_name: Nicholas full_name: Brandt, Nicholas last_name: Brandt - first_name: Miguel full_name: Cueto Noval, Miguel id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc last_name: Cueto Noval orcid: 0000-0002-2505-4246 - first_name: Christoph Ullrich full_name: Günther, Christoph Ullrich id: ec98511c-eb8e-11eb-b029-edd25d7271a1 last_name: Günther - first_name: Akin full_name: Ünal, Akin id: f6b56fb6-dc63-11ee-9dbf-f6780863a85a last_name: Ünal orcid: 0000-0002-8929-0221 - first_name: Stella full_name: Wohnig, Stella last_name: Wohnig citation: ama: 'Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. Constrained verifiable random functions without obfuscation and friends. In: 23rd International Conference on Theory of Cryptography. Vol 16271. Springer Nature; 2025:478-511. doi:10.1007/978-3-032-12290-2_16' apa: 'Brandt, N., Cueto Noval, M., Günther, C. U., Ünal, A., & Wohnig, S. (2025). Constrained verifiable random functions without obfuscation and friends. In 23rd International Conference on Theory of Cryptography (Vol. 16271, pp. 478–511). Aarhus, Denmark: Springer Nature. https://doi.org/10.1007/978-3-032-12290-2_16' chicago: Brandt, Nicholas, Miguel Cueto Noval, Christoph Ullrich Günther, Akin Ünal, and Stella Wohnig. “Constrained Verifiable Random Functions without Obfuscation and Friends.” In 23rd International Conference on Theory of Cryptography, 16271:478–511. Springer Nature, 2025. https://doi.org/10.1007/978-3-032-12290-2_16. ieee: N. Brandt, M. Cueto Noval, C. U. Günther, A. Ünal, and S. Wohnig, “Constrained verifiable random functions without obfuscation and friends,” in 23rd International Conference on Theory of Cryptography, Aarhus, Denmark, 2025, vol. 16271, pp. 478–511. ista: 'Brandt N, Cueto Noval M, Günther CU, Ünal A, Wohnig S. 2025. Constrained verifiable random functions without obfuscation and friends. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 478–511.' mla: Brandt, Nicholas, et al. “Constrained Verifiable Random Functions without Obfuscation and Friends.” 23rd International Conference on Theory of Cryptography, vol. 16271, Springer Nature, 2025, pp. 478–511, doi:10.1007/978-3-032-12290-2_16. short: N. Brandt, M. Cueto Noval, C.U. Günther, A. Ünal, S. Wohnig, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 478–511. conference: end_date: 2025-12-05 location: Aarhus, Denmark name: 'TCC: Theory of Cryptography' start_date: 2025-12-01 corr_author: '1' date_created: 2025-12-21T23:01:34Z date_published: 2025-12-05T00:00:00Z date_updated: 2025-12-29T11:11:29Z day: '05' department: - _id: KrPi doi: 10.1007/978-3-032-12290-2_16 intvolume: ' 16271' language: - iso: eng main_file_link: - open_access: '1' url: https://eprint.iacr.org/2025/1045 month: '12' oa: 1 oa_version: Preprint page: 478-511 project: - _id: 34a34d57-11ca-11ed-8bc3-a2688a8724e1 grant_number: F8509 name: Security and Privacy by Design for Complex Systems publication: 23rd International Conference on Theory of Cryptography publication_identifier: eissn: - 1611-3349 isbn: - '9783032122896' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Constrained verifiable random functions without obfuscation and friends type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 16271 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '20847' abstract: - lang: eng text: "We report on an experimental active matter system with motion restricted to four cardinal directions. Our particles are magnetite-doped colloidal spheres driven by the Quincke electrorotational instability. The absence of a magnetic field (|\U0001D469|=0) leads to circular trajectories interspersed with short spontaneous runs. Intermediate fields (|\U0001D469|≲20mT) linearize the motion along the axis perpendicular to \U0001D469. At high magnetic fields, we observe the surprising emergence of a second, distinct linearization along the axis parallel to \U0001D469. With numerical simulations, we show that this behavior can be explained by anisotropic magnetic susceptibility." acknowledged_ssus: - _id: M-Shop - _id: NanoFab - _id: ScienComp - _id: LifeSc acknowledgement: "This research was funded in whole or in part by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant\r\nAgreement No. 949120). This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge the crucial contributions of Alexandre Morin in getting the project off the ground, and Jack Merrin for creating the SU-8 deposition protocol used in the construction of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their work on single-particle characterization. " article_number: '065418' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Eavan full_name: Fitzgerald, Eavan id: 2df8ab8f-080d-11ed-979a-bfe651ca3afa last_name: Fitzgerald - first_name: Cécile full_name: Clavaud, Cécile id: 5f654c5d-04a1-11eb-ab36-ba9ffec58bd8 last_name: Clavaud orcid: 0000-0002-1843-3803 - first_name: Debasish full_name: Das, Debasish last_name: Das - first_name: Isaac C full_name: Lenton, Isaac C id: a550210f-223c-11ec-8182-e2d45e817efb last_name: Lenton orcid: 0000-0002-5010-6984 - first_name: Scott R full_name: Waitukaitis, Scott R id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87 last_name: Waitukaitis orcid: 0000-0002-2299-3176 citation: ama: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 2025;112(6). doi:10.1103/1ss8-31rb' apa: 'Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., & Waitukaitis, S. R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. American Physical Society. https://doi.org/10.1103/1ss8-31rb' chicago: 'Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” Physical Review E. American Physical Society, 2025. https://doi.org/10.1103/1ss8-31rb.' ieee: 'E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter,” Physical Review E, vol. 112, no. 6. American Physical Society, 2025.' ista: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 112(6), 065418.' mla: 'Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” Physical Review E, vol. 112, no. 6, 065418, American Physical Society, 2025, doi:10.1103/1ss8-31rb.' short: E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical Review E 112 (2025). corr_author: '1' date_created: 2025-12-21T23:01:34Z date_published: 2025-12-01T00:00:00Z date_updated: 2025-12-29T11:19:34Z day: '01' ddc: - '530' department: - _id: ScWa doi: 10.1103/1ss8-31rb ec_funded: 1 external_id: arxiv: - '2508.05643' file: - access_level: open_access checksum: d593e933f976c3f3cde37ad66539d57d content_type: application/pdf creator: dernst date_created: 2025-12-29T11:15:42Z date_updated: 2025-12-29T11:15:42Z file_id: '20862' file_name: 2025_PhysReviewE_Fitzgerald.pdf file_size: 2131491 relation: main_file success: 1 file_date_updated: 2025-12-29T11:15:42Z has_accepted_license: '1' intvolume: ' 112' issue: '6' language: - iso: eng month: '12' oa: 1 oa_version: Published Version project: - _id: bd8eede5-d553-11ed-ba76-eaded0d13485 grant_number: E 298 name: 'MixQUIckR: Mixing with QUIncke Rollers' - _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa call_identifier: H2020 grant_number: '949120' name: 'Tribocharge: a multi-scale approach to an enduring problem in physics' publication: Physical Review E publication_identifier: eissn: - 2470-0053 issn: - 2470-0045 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: 'Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 112 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '20848' abstract: - lang: eng text: 'Genetic variation that influences complex disease susceptibility is introduced into the population by mutation and removed by natural selection and genetic drift. This mutation–selection–drift balance (MSDB) shapes the prevalence of a disease and its genetic architecture. To date, however, MSDB has been modeled only for monogenic (Mendelian) diseases. Here, we develop an MSDB model for complex disease susceptibility: we assume that genotype relates to disease risk according to the canonical liability threshold model and that the selection on variants affecting risk stems from the fitness cost of the disease. We focus on diseases that are highly polygenic, entail a substantial fitness cost, and are neither extremely common in the population nor exceedingly rare. The comparison of model predictions with genome-wide association studies and other observations in humans indicates that common genetic variation affecting complex disease susceptibility is little affected by directional selection and instead shaped by pleiotropic stabilizing selection on other traits. In turn, directional selection may exert a more substantial effect on rare, large-effect variants. Our results also suggest that current estimates of disease heritability are likely biased. The model thus provides a better understanding of the evolutionary processes that shape the architecture and prevalence of complex diseases.' acknowledgement: We thank Nick Barton, Magnus Nordborg, John Novembre, Molly Przeworski, and Himani Sachdeva for many helpful discussions and for comments on the manuscript, and we thank Joshua Schraiber and 2 anonymous reviewers for comments on the manuscript. We also thank members of the Sella, Przeworski and Andolfatto labs at Columbia University, and the Berg, Novembre and Steinrücken labs at the University of Chicago, for feedback on the work at various stages. This work was completed in part with resources provided by the University of Chicago's Research Computing Center. This work was supported by National Institutes of Health F32 grant GM126787 and R35 grant GM151257 to J.J.B. and National Institutes of Health R01 grant GM115889 to G.S. article_number: iyaf220 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Jeremy J. full_name: Berg, Jeremy J. last_name: Berg - first_name: Xinyi full_name: Li, Xinyi last_name: Li - first_name: Kellen full_name: Riall, Kellen last_name: Riall - first_name: Laura full_name: Hayward, Laura id: fc885ee5-24bf-11eb-ad7b-bcc5104c0c1b last_name: Hayward - first_name: Guy full_name: Sella, Guy last_name: Sella citation: ama: Berg JJ, Li X, Riall K, Hayward L, Sella G. Mutation–selection–drift balance models of complex diseases. Genetics. 2025;231(4). doi:10.1093/genetics/iyaf220 apa: Berg, J. J., Li, X., Riall, K., Hayward, L., & Sella, G. (2025). Mutation–selection–drift balance models of complex diseases. Genetics. Oxford University Press. https://doi.org/10.1093/genetics/iyaf220 chicago: Berg, Jeremy J., Xinyi Li, Kellen Riall, Laura Hayward, and Guy Sella. “Mutation–Selection–Drift Balance Models of Complex Diseases.” Genetics. Oxford University Press, 2025. https://doi.org/10.1093/genetics/iyaf220. ieee: J. J. Berg, X. Li, K. Riall, L. Hayward, and G. Sella, “Mutation–selection–drift balance models of complex diseases,” Genetics, vol. 231, no. 4. Oxford University Press, 2025. ista: Berg JJ, Li X, Riall K, Hayward L, Sella G. 2025. Mutation–selection–drift balance models of complex diseases. Genetics. 231(4), iyaf220. mla: Berg, Jeremy J., et al. “Mutation–Selection–Drift Balance Models of Complex Diseases.” Genetics, vol. 231, no. 4, iyaf220, Oxford University Press, 2025, doi:10.1093/genetics/iyaf220. short: J.J. Berg, X. Li, K. Riall, L. Hayward, G. Sella, Genetics 231 (2025). date_created: 2025-12-21T23:01:34Z date_published: 2025-12-01T00:00:00Z date_updated: 2025-12-29T11:29:16Z day: '01' ddc: - '570' department: - _id: NiBa doi: 10.1093/genetics/iyaf220 external_id: pmid: - '41073879' file: - access_level: open_access checksum: b02eb6b78028b8bef435edc8435a8468 content_type: application/pdf creator: dernst date_created: 2025-12-29T11:27:51Z date_updated: 2025-12-29T11:27:51Z file_id: '20863' file_name: 2025_Genetics_Berg.pdf file_size: 1182339 relation: main_file success: 1 file_date_updated: 2025-12-29T11:27:51Z has_accepted_license: '1' intvolume: ' 231' issue: '4' language: - iso: eng month: '12' oa: 1 oa_version: Published Version pmid: 1 publication: Genetics publication_identifier: eissn: - 1943-2631 issn: - 0016-6731 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: Mutation–selection–drift balance models of complex diseases tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 231 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '20850' abstract: - lang: eng text: We provide an estimate for the number of nontrivial integer points on the Pellian surface t^2 - du^2 = 1 in a bounded region. We give a lower bound on the size of fundamental solutions for almost all d in a certain class, based on a recent conjecture of Browning and Wilsch about integer points on log K3 surfaces. We also obtain an upper bound on the average of class number in this class, assuming the same conjecture. - lang: fre text: "Nous donnons une estimation du nombre de points entiers non triviaux sur la surface pellienne \r\nt^2 - du^2 = 1 dans une région bornée. Nous établissons une borne inférieure pour la taille des solutions fondamentales pour presque tout d appartenant à une certaine classe, en nous fondant sur une conjecture récente de Browning et Wilsch concernant les points entiers sur les surfaces log K3. Nous obtenons également une borne supérieure pour la moyenne du nombre de classes dans cette classe, sous la même hypothèse conjecturale." acknowledgement: The author would like to thank his supervisor Tim Browning for suggesting this project and many helpful conversations and useful comments. Moreover, he is grateful to Jakob Glas, Damaris Schindler, Igor Shparlinski, Matteo Verzobio, Victor Wang, Florian Wilsch and Shuntaro Yamagishi for taking their time to answer his questions and their valuable suggestions. article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Yijie full_name: Diao, Yijie id: 7b7eb4ca-eb2c-11ec-b98b-accec0b20c3b last_name: Diao orcid: 0000-0002-4989-5330 citation: ama: Diao Y. Class numbers and integer points on some Pellian surfaces. Journal de theorie des nombres de Bordeaux. 2025;37(3):973-988. doi:10.5802/jtnb.1348 apa: Diao, Y. (2025). Class numbers and integer points on some Pellian surfaces. Journal de Theorie Des Nombres de Bordeaux. Université de Bordeaux. https://doi.org/10.5802/jtnb.1348 chicago: Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.” Journal de Theorie Des Nombres de Bordeaux. Université de Bordeaux, 2025. https://doi.org/10.5802/jtnb.1348. ieee: Y. Diao, “Class numbers and integer points on some Pellian surfaces,” Journal de theorie des nombres de Bordeaux, vol. 37, no. 3. Université de Bordeaux, pp. 973–988, 2025. ista: Diao Y. 2025. Class numbers and integer points on some Pellian surfaces. Journal de theorie des nombres de Bordeaux. 37(3), 973–988. mla: Diao, Yijie. “Class Numbers and Integer Points on Some Pellian Surfaces.” Journal de Theorie Des Nombres de Bordeaux, vol. 37, no. 3, Université de Bordeaux, 2025, pp. 973–88, doi:10.5802/jtnb.1348. short: Y. Diao, Journal de Theorie Des Nombres de Bordeaux 37 (2025) 973–988. corr_author: '1' date_created: 2025-12-21T23:01:35Z date_published: 2025-11-27T00:00:00Z date_updated: 2025-12-29T10:08:46Z day: '27' ddc: - '510' department: - _id: TiBr doi: 10.5802/jtnb.1348 external_id: arxiv: - '2408.03774' file: - access_level: open_access checksum: 67aa0afbc0b5bcbff5341f4d25e6ba20 content_type: application/pdf creator: dernst date_created: 2025-12-29T10:05:22Z date_updated: 2025-12-29T10:05:22Z file_id: '20861' file_name: 2025_JTNB_Diao.pdf file_size: 766196 relation: main_file success: 1 file_date_updated: 2025-12-29T10:05:22Z has_accepted_license: '1' intvolume: ' 37' issue: '3' language: - iso: eng license: https://creativecommons.org/licenses/by-nd/4.0/ month: '11' oa: 1 oa_version: Published Version page: 973-988 publication: Journal de theorie des nombres de Bordeaux publication_identifier: eissn: - 2118-8572 issn: - 1246-7405 publication_status: published publisher: Université de Bordeaux quality_controlled: '1' scopus_import: '1' status: public title: Class numbers and integer points on some Pellian surfaces tmp: image: /image/cc_by_nd.png legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) short: CC BY-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 37 year: '2025' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '20851' abstract: - lang: eng text: High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material for high power density in lithium-ion batteries. However, it suffers from poor cycle life associated with the rock-salt phase transformation. This study presents a straightforward synthesis approach to enhance the electrochemical performance of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4, and, more importantly, effectively mitigates the formation of the rock-salt phase, thereby enhancing structural stability, as confirmed by operando X-ray absorption spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C, 2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode and a high-loading cathode exhibit excellent cycling performance. They retain 80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9 V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and thereby enhancing their potential for practical applications. acknowledged_ssus: - _id: EM-Fac - _id: NanoFab acknowledgement: 'This work was supported by the European Commission-financed project IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This research was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033 and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.' article_number: e15962 article_processing_charge: Yes article_type: original author: - first_name: Xingqi full_name: Chang, Xingqi last_name: Chang - first_name: Carlos full_name: Escudero, Carlos last_name: Escudero - first_name: Ashley P. full_name: Black, Ashley P. last_name: Black - first_name: Sharona full_name: Horta, Sharona id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc last_name: Horta - first_name: Elías full_name: Martínez, Elías last_name: Martínez - first_name: Xuan full_name: Lu, Xuan last_name: Lu - first_name: Jordi full_name: Llorca, Jordi last_name: Llorca - first_name: Maria full_name: Ibáñez, Maria id: 43C61214-F248-11E8-B48F-1D18A9856A87 last_name: Ibáñez orcid: 0000-0001-5013-2843 - first_name: Jordi Jacas full_name: Biendicho, Jordi Jacas last_name: Biendicho - first_name: Andreu full_name: Cabot, Andreu last_name: Cabot citation: ama: Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science. 2025. doi:10.1002/advs.202515962 apa: Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot, A. (2025). Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science. Wiley. https://doi.org/10.1002/advs.202515962 chicago: Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez, Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” Advanced Science. Wiley, 2025. https://doi.org/10.1002/advs.202515962. ieee: X. Chang et al., “Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications,” Advanced Science. Wiley, 2025. ista: Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez M, Biendicho JJ, Cabot A. 2025. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science., e15962. mla: Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” Advanced Science, e15962, Wiley, 2025, doi:10.1002/advs.202515962. short: X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca, M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science (2025). date_created: 2025-12-21T23:01:35Z date_published: 2025-12-12T00:00:00Z date_updated: 2025-12-29T10:15:43Z day: '12' ddc: - '540' department: - _id: MaIb doi: 10.1002/advs.202515962 has_accepted_license: '1' language: - iso: eng month: '12' oa_version: Published Version project: - _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery' publication: Advanced Science publication_identifier: eissn: - 2198-3844 publication_status: epub_ahead publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2025' ... --- APC_amount: 3003,56 EUR OA_place: publisher OA_type: hybrid _id: '20857' abstract: - lang: eng text: 'Evolutionary games provide a flexible mathematical framework for many problems in biology and social evolution. Prisoners’ dilemma, and in particular, the important special case of donation games, represents social dilemmas where cooperation is mutually beneficial, yet defection is preferred by selfish agents. In evolutionary games on networks, the agents interact over a population structure. The existence of population structures that promote cooperative behavior is a fascinating and active research topic. Previous research establishes structures promoting cooperation in the limit of weak selection where the benefit-to-cost ratio β exceeds 1.5. The existence of such structures for medium and strong selection for 1 < ß < 2 and for weak selection for 1 < ß < 1.5 has been a long-standing open question. First, we answer the open questions in the affirmative: For every selection strength and every ß > 1, we construct networks promoting cooperation. Second, we present a robustness result with respect to β and selection strength: Our structures promote cooperation for a range of these parameter values rather than specific parameter values. Finally, we supplement our theoretical results with simulation results on small population structures that show the effectiveness of our construction over well-studied population structures.' acknowledgement: J.S. and K.C. were supported by the European Research Council CoG 863818 (ForM-SMArt) and Austrian Science Fund (FWF) 10.55776/COE12. article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Jakub full_name: Svoboda, Jakub id: 130759D2-D7DD-11E9-87D2-DE0DE6697425 last_name: Svoboda orcid: 0000-0002-1419-3267 - first_name: Krishnendu full_name: Chatterjee, Krishnendu id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87 last_name: Chatterjee orcid: 0000-0002-4561-241X citation: ama: Svoboda J, Chatterjee K. Promoters of cooperation in evolutionary games. Proceedings of the National Academy of Sciences. 2025;122(51):e2524109122. doi:10.1073/pnas.2524109122 apa: Svoboda, J., & Chatterjee, K. (2025). Promoters of cooperation in evolutionary games. Proceedings of the National Academy of Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.2524109122 chicago: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” Proceedings of the National Academy of Sciences. National Academy of Sciences, 2025. https://doi.org/10.1073/pnas.2524109122. ieee: J. Svoboda and K. Chatterjee, “Promoters of cooperation in evolutionary games,” Proceedings of the National Academy of Sciences, vol. 122, no. 51. National Academy of Sciences, p. e2524109122, 2025. ista: Svoboda J, Chatterjee K. 2025. Promoters of cooperation in evolutionary games. Proceedings of the National Academy of Sciences. 122(51), e2524109122. mla: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” Proceedings of the National Academy of Sciences, vol. 122, no. 51, National Academy of Sciences, 2025, p. e2524109122, doi:10.1073/pnas.2524109122. short: J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences 122 (2025) e2524109122. corr_author: '1' date_created: 2025-12-28T23:01:26Z date_published: 2025-12-15T00:00:00Z date_updated: 2026-05-20T08:13:17Z day: '15' ddc: - '000' department: - _id: KrCh doi: 10.1073/pnas.2524109122 ec_funded: 1 external_id: pmid: - '41397136' file: - access_level: open_access checksum: dd50b62a1efc28c0133fe9c11dbee53c content_type: application/pdf creator: dernst date_created: 2025-12-29T09:36:50Z date_updated: 2025-12-29T09:36:50Z file_id: '20860' file_name: 2025_PNAS_Svoboda.pdf file_size: 2308124 relation: main_file success: 1 file_date_updated: 2025-12-29T09:36:50Z has_accepted_license: '1' intvolume: ' 122' issue: '51' language: - iso: eng month: '12' oa: 1 oa_version: Published Version page: e2524109122 pmid: 1 project: - _id: 0599E47C-7A3F-11EA-A408-12923DDC885E call_identifier: H2020 grant_number: '863818' name: 'Formal Methods for Stochastic Models: Algorithms and Applications' publication: Proceedings of the National Academy of Sciences publication_identifier: eissn: - 1091-6490 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' scopus_import: '1' status: public title: Promoters of cooperation in evolutionary games tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 122 year: '2025' ... --- OA_place: repository OA_type: green _id: '20858' abstract: - lang: eng text: Targeted antigen delivery to immune cells, particularly dendritic cells, has emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while minimizing adverse effects associated with conventional immunization. In this study, we use our previously described small glycomimetic molecule that is selectively recognized by the Langerhans cell (LC)-specific surface receptor Langerin and demonstrate specific delivery of protein antigens to these specialized dendritic cells. Our results show that Langerin-mediated antigen delivery significantly enhances the immune response in vivo, resulting in increased expansion and activation of antigen-specific T cells, compared to immunization with unmodified antigen. We demonstrate the feasibility of our LC-targeted platform for immune cell-specific immunization with protein antigen and underscore the potential of LCs as an access point for next-generation vaccines and immunotherapies. acknowledgement: This project was generously supported by Seedfinancing (grant no. P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation, und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science and Technology Austria for his continuous technical support. article_processing_charge: No article_type: original author: - first_name: Ramona full_name: Rica, Ramona last_name: Rica - first_name: Klara full_name: Klein, Klara last_name: Klein - first_name: Litty full_name: Johnson, Litty last_name: Johnson - first_name: Gabriele full_name: Carta, Gabriele last_name: Carta - first_name: Mirza full_name: Sarcevic, Mirza last_name: Sarcevic - first_name: Freyja full_name: Langer, Freyja id: 3C1BE782-F248-11E8-B48F-1D18A9856A87 last_name: Langer - first_name: Christoph full_name: Rademacher, Christoph last_name: Rademacher - first_name: Robert full_name: Wawrzinek, Robert last_name: Wawrzinek - first_name: Federica full_name: Quattrone, Federica last_name: Quattrone - first_name: Florian full_name: Sparber, Florian last_name: Sparber citation: ama: Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. doi:10.1016/j.ymthe.2025.10.008 apa: Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber, F. (n.d.). Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. Elsevier. https://doi.org/10.1016/j.ymthe.2025.10.008 chicago: Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic, Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” Molecular Therapy. Elsevier, n.d. https://doi.org/10.1016/j.ymthe.2025.10.008. ieee: R. Rica et al., “Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response,” Molecular Therapy. Elsevier. ista: Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy. mla: Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” Molecular Therapy, Elsevier, doi:10.1016/j.ymthe.2025.10.008. short: R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy (n.d.). date_created: 2025-12-28T23:01:26Z date_published: 2025-10-04T00:00:00Z date_updated: 2025-12-29T09:55:05Z day: '04' department: - _id: PreCl doi: 10.1016/j.ymthe.2025.10.008 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1101/2025.05.05.652195 month: '10' oa: 1 oa_version: Preprint publication: Molecular Therapy publication_identifier: eissn: - 1525-0024 issn: - 1525-0016 publication_status: inpress publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2025' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '20859' abstract: - lang: eng text: Effective immune responses rely on the efficient migration of leukocytes. Yet, how temperature regulates migration dynamics at the single-cell level has remained poorly understood. Using zebrafish embryos and mouse tissue explants, we found that temperature positively regulates leukocyte migration speed, exploration, and arrival frequencies to wounds and lymph vessels. Complementary 2D and 3D cultures revealed that this thermokinetic control of cell migration is conserved across immune cell types, independently of the 3D tissue environment. By applying precise (sub-)cellular temperature modulation, we identified a rapid and reversible thermo-response that depends on myosin II activity. Small physiological increases in temperature (1°C –2°C), as present during fever-like conditions, profoundly increased immune responses by accelerating arrival times at lymphatic vessels and tissue wounds. These findings identify myosin-II-dependent actomyosin contractility as a critical mechanical structure regulating single-cell thermo-adaptability, with physiological implications for tuning the speed of immune responses in vivo. acknowledged_ssus: - _id: NanoFab acknowledgement: 'The authors would like to acknowledge the Super Resolution Light Microcopy and Nanoscopy (SLN) Facility of ICFO for their support with imaging experiments, Johann Osmond (Nanofabrication laboratory, ICFO) for the design and production of molds for generating confinement coverslip, Merche Rivas for cell culture of immune cells and further support from the CRG Core Facilities for Genomics and Advanced Light Microscopy. We would like to thank Michael Sixt for discussions on this work and the Quidant, Ruprecht, and Wieser lab members for critical reading of the manuscript. This research was supported by the Scientific Service Units (SSU) of IST-Austria through resources provided by the Nanofabrication Facility (NFF). C.A. acknowledges the funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 847517 and V.V. from the ICFOstepstone – PhD Programme funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 665884. S.W. acknowledges support through the Spanish Ministry of Economy and Competitiveness via MINECO’s Plan Nacional (BFU2017-86296-P). V.R. acknowledges funding from the European Union’s HORIZON-EIC-2021-PATHFINDEROPEN program under grant agreement no. 101046620 and European Union''s Horizon Europe program under the grant agreement no. 101072123. E.K. acknowledges funding by a fellowship of the Ministry of Innovation, Science and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2151 – 390873048 and by the TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments.' article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Iván full_name: Company-Garrido, Iván last_name: Company-Garrido - first_name: Alberto full_name: Zurita Carpio, Alberto last_name: Zurita Carpio - first_name: Mariona full_name: Colomer-Rosell, Mariona last_name: Colomer-Rosell - first_name: Bernard full_name: Ciraulo, Bernard last_name: Ciraulo - first_name: Ronja full_name: Molkenbur, Ronja last_name: Molkenbur - first_name: Peter full_name: Lanzerstorfer, Peter last_name: Lanzerstorfer - first_name: Fabio full_name: Pezzano, Fabio last_name: Pezzano - first_name: Costanza full_name: Agazzi, Costanza last_name: Agazzi - first_name: Robert full_name: Hauschild, Robert id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87 last_name: Hauschild orcid: 0000-0001-9843-3522 - first_name: Saumey full_name: Jain, Saumey last_name: Jain - first_name: Jeroen M. full_name: Jacques, Jeroen M. last_name: Jacques - first_name: Valeria full_name: Venturini, Valeria last_name: Venturini - first_name: Christian full_name: Knapp, Christian last_name: Knapp - first_name: Yufei full_name: Xie, Yufei last_name: Xie - first_name: Jack full_name: Merrin, Jack id: 4515C308-F248-11E8-B48F-1D18A9856A87 last_name: Merrin orcid: 0000-0001-5145-4609 - first_name: Julian full_name: Weghuber, Julian last_name: Weghuber - first_name: Marcel full_name: Schaaf, Marcel last_name: Schaaf - first_name: Romain full_name: Quidant, Romain last_name: Quidant - first_name: Eva full_name: Kiermaier, Eva id: 3EB04B78-F248-11E8-B48F-1D18A9856A87 last_name: Kiermaier orcid: 0000-0001-6165-5738 - first_name: Jaime full_name: Ortega Arroyo, Jaime last_name: Ortega Arroyo - first_name: Verena full_name: Ruprecht, Verena id: 4D71A03A-F248-11E8-B48F-1D18A9856A87 last_name: Ruprecht orcid: 0000-0003-4088-8633 - first_name: Stefan full_name: Wieser, Stefan id: 355AA5A0-F248-11E8-B48F-1D18A9856A87 last_name: Wieser orcid: 0000-0002-2670-2217 citation: ama: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, et al. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Developmental Cell. 2025. doi:10.1016/j.devcel.2025.10.006 apa: Company-Garrido, I., Zurita Carpio, A., Colomer-Rosell, M., Ciraulo, B., Molkenbur, R., Lanzerstorfer, P., … Wieser, S. (2025). Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2025.10.006 chicago: Company-Garrido, Iván, Alberto Zurita Carpio, Mariona Colomer-Rosell, Bernard Ciraulo, Ronja Molkenbur, Peter Lanzerstorfer, Fabio Pezzano, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” Developmental Cell. Elsevier, 2025. https://doi.org/10.1016/j.devcel.2025.10.006. ieee: I. Company-Garrido et al., “Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses,” Developmental Cell. Elsevier, 2025. ista: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, Ciraulo B, Molkenbur R, Lanzerstorfer P, Pezzano F, Agazzi C, Hauschild R, Jain S, Jacques JM, Venturini V, Knapp C, Xie Y, Merrin J, Weghuber J, Schaaf M, Quidant R, Kiermaier E, Ortega Arroyo J, Ruprecht V, Wieser S. 2025. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Developmental Cell. mla: Company-Garrido, Iván, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” Developmental Cell, Elsevier, 2025, doi:10.1016/j.devcel.2025.10.006. short: I. Company-Garrido, A. Zurita Carpio, M. Colomer-Rosell, B. Ciraulo, R. Molkenbur, P. Lanzerstorfer, F. Pezzano, C. Agazzi, R. Hauschild, S. Jain, J.M. Jacques, V. Venturini, C. Knapp, Y. Xie, J. Merrin, J. Weghuber, M. Schaaf, R. Quidant, E. Kiermaier, J. Ortega Arroyo, V. Ruprecht, S. Wieser, Developmental Cell (2025). date_created: 2025-12-28T23:01:27Z date_published: 2025-11-04T00:00:00Z date_updated: 2025-12-29T09:23:58Z day: '04' ddc: - '570' department: - _id: Bio - _id: NanoFab doi: 10.1016/j.devcel.2025.10.006 external_id: pmid: - '41192429' has_accepted_license: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.devcel.2025.10.006 month: '11' oa: 1 oa_version: Published Version pmid: 1 publication: Developmental Cell publication_identifier: eissn: - 1878-1551 issn: - 1534-5807 publication_status: epub_ahead publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2025' ... --- OA_place: repository OA_type: green _id: '20864' abstract: - lang: eng text: Studies of the distant Universe are providing key insights into our understanding of the formation of galaxies. The advent of the James Webb Space Telescope (JWST) has significantly enhanced our observational capabilities, leading to an expanded redshift frontier, providing unprecedented detail in the characterisation of early galaxies and enabling the discovery of new populations of accreting black holes. This review aims to provide an introduction to the basic processes and components that shape the observed spectra of galaxies, with a focus on their relevance to techniques with which high-redshift galaxies are selected. The review further introduces specific topics that have attracted significant attention in recent literature, including the discovery of highly efficient galaxy formation in the early Universe, the relation between galaxies and the process of reionization, new insights into the formation of the first stars and the enrichment of interstellar gas with heavy elements, and breakthroughs in our understanding of the origins of supermassive black holes. acknowledgement: I thank Claudia Di Cesare, Edoardo Iani, Gauri Kotiwale and Wendy Sun for proofreading, Daichi Kashino, Gauri Kotiwale, Sara Mascia, Benjamín Navarette and Joris Witstok for their assistance in preparing some of the Figures, and Richard Ellis and Stephen Blundell for constructive comments. Funded by the European Union (ERC, AGENTS, 101076224). article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X citation: ama: 'Matthee JJ. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. 2025;66(1-4):116-151. doi:10.1080/00107514.2025.2586370' apa: 'Matthee, J. J. (2025). JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. Taylor & Francis. https://doi.org/10.1080/00107514.2025.2586370' chicago: 'Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” Contemporary Physics. Taylor & Francis, 2025. https://doi.org/10.1080/00107514.2025.2586370.' ieee: 'J. J. Matthee, “JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies,” Contemporary Physics, vol. 66, no. 1–4. Taylor & Francis, pp. 116–151, 2025.' ista: 'Matthee JJ. 2025. JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies. Contemporary Physics. 66(1–4), 116–151.' mla: 'Matthee, Jorryt J. “JWST Provides a New View of Cosmic Dawn: Latest Developments in Studies of Early Galaxies.” Contemporary Physics, vol. 66, no. 1–4, Taylor & Francis, 2025, pp. 116–51, doi:10.1080/00107514.2025.2586370.' short: J.J. Matthee, Contemporary Physics 66 (2025) 116–151. corr_author: '1' date_created: 2025-12-29T12:05:25Z date_published: 2025-12-04T00:00:00Z date_updated: 2026-04-07T08:44:00Z day: '04' department: - _id: JoMa doi: 10.1080/00107514.2025.2586370 external_id: arxiv: - '2511.04843' intvolume: ' 66' issue: 1-4 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2511.04843 month: '12' oa: 1 oa_version: Preprint page: 116-151 project: - _id: bd9b2118-d553-11ed-ba76-db24564edfea grant_number: '101076224' name: Young galaxies as tracers and agents of cosmic reionization publication: Contemporary Physics publication_identifier: eissn: - 1366-5812 issn: - 0010-7514 publication_status: published publisher: Taylor & Francis quality_controlled: '1' scopus_import: '1' status: public title: 'JWST provides a new view of cosmic dawn: Latest developments in studies of early galaxies' type: journal_article user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd volume: 66 year: '2025' ... --- OA_place: publisher OA_type: hybrid _id: '20866' abstract: - lang: eng text: In this work, we present hypernode automata as a specification formalism for hyperproperties of systems whose executions may be misaligned among themselves, such as concurrent systems. These automata consist of nodes labeled with hypernode logic formulas and transitions marked with synchronizing actions. Hypernode logic formulas establish relations between sequences of variable values among different system executions. This logic enables both synchronous and asynchronous analysis of traces. In its asynchronous view on execution traces, hypernode formulas establish relations on the order of value changes for each variable without correlating their timing. In both views, the analysis of different execution traces is synchronized through the transitions of hypernode automata. By combining logic’s declarative nature with automata’s procedural power, hypernode automata seamlessly integrate asynchronicity requirements at the node level with synchronicity between node transitions. We show that the model-checking problem for hypernode automata is decidable for specifications where each node specifies either a synchronous or an asynchronous requirement for the system’s executions, but not both. acknowledgement: This work was supported in part by the Austrian Science Fund (FWF) SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute of Science and Technology (IST Austria). article_number: '43' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Ezio full_name: Bartocci, Ezio last_name: Bartocci - first_name: Marek full_name: Chalupa, Marek id: 87e34708-d6c6-11ec-9f5b-9391e7be2463 last_name: Chalupa - first_name: Thomas A full_name: Henzinger, Thomas A id: 40876CD8-F248-11E8-B48F-1D18A9856A87 last_name: Henzinger orcid: 0000-0002-2985-7724 - first_name: Dejan full_name: Nickovic, Dejan id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87 last_name: Nickovic - first_name: Ana full_name: Oliveira da Costa, Ana id: f347ec37-6676-11ee-b395-a888cb7b4fb4 last_name: Oliveira da Costa orcid: 0000-0002-8741-5799 citation: ama: Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. Acta Informatica. 2025;62(4). doi:10.1007/s00236-025-00509-8 apa: Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., & Oliveira da Costa, A. (2025). Hypernode automata. Acta Informatica. Springer Nature. https://doi.org/10.1007/s00236-025-00509-8 chicago: Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” Acta Informatica. Springer Nature, 2025. https://doi.org/10.1007/s00236-025-00509-8. ieee: E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” Acta Informatica, vol. 62, no. 4. Springer Nature, 2025. ista: Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Hypernode automata. Acta Informatica. 62(4), 43. mla: Bartocci, Ezio, et al. “Hypernode Automata.” Acta Informatica, vol. 62, no. 4, 43, Springer Nature, 2025, doi:10.1007/s00236-025-00509-8. short: E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Acta Informatica 62 (2025). corr_author: '1' date_created: 2025-12-29T12:07:12Z date_published: 2025-12-09T00:00:00Z date_updated: 2026-01-05T12:27:41Z day: '09' ddc: - '000' department: - _id: ToHe doi: 10.1007/s00236-025-00509-8 ec_funded: 1 external_id: arxiv: - '2305.02836' file: - access_level: open_access checksum: 06ed45a1218ad8464818803ae2968aaf content_type: application/pdf creator: dernst date_created: 2026-01-05T12:26:43Z date_updated: 2026-01-05T12:26:43Z file_id: '20944' file_name: 2025_ActaInformatica_Bartocci.pdf file_size: 7117003 relation: main_file success: 1 file_date_updated: 2026-01-05T12:26:43Z has_accepted_license: '1' intvolume: ' 62' issue: '4' language: - iso: eng month: '12' oa: 1 oa_version: Published Version project: - _id: 62781420-2b32-11ec-9570-8d9b63373d4d call_identifier: H2020 grant_number: '101020093' name: Vigilant Algorithmic Monitoring of Software - _id: 34a1b658-11ca-11ed-8bc3-c75229f0241e grant_number: F8502 name: Interface Theory for Security and Privacy publication: Acta Informatica publication_identifier: eissn: - 1432-0525 issn: - 0001-5903 publication_status: published publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '14405' relation: earlier_version status: public scopus_import: '1' status: public title: Hypernode automata tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 62 year: '2025' ... --- OA_place: publisher OA_type: diamond PlanS_conform: '1' _id: '20867' abstract: - lang: eng text: We discuss the embeddability of subspaces of the Gromov–Hausdorff space, which consists of isometry classes of compact metric spaces endowed with the Gromov–Hausdorff distance, into Hilbert spaces. These embeddings are particularly valuable for applications to topological data analysis. We prove that its subspace consisting of metric spaces with at most n points has asymptotic dimension n(n−1)∕2. Thus, there exists a coarse embedding of that space into a Hilbert space. On the contrary, if the number of points is not bounded, then the subspace cannot be coarsely embedded into any uniformly convex Banach space and so, in particular, into any Hilbert space. Furthermore, we prove that, even if we restrict to finite metric spaces whose diameter is bounded by some constant, the subspace still cannot be bi-Lipschitz embedded into any finite-dimensional Hilbert space. We obtain both nonembeddability results by finding obstructions to coarse and bi-Lipschitz embeddings in families of isometry classes of finite subsets of the real line endowed with the Euclidean–Hausdorff distance. acknowledgement: "The author was supported by the FWF Grant, Project number I4245-N35. The author would like to thank Thomas Weighill for the helpful discussions around Theorem 3.10, and Takamitsu Yamauchi for bringing to my attention the fundamental reference [35]. Furthermore, the author\r\nis thankful for the detailed and helpful comments of the reviewer of this manuscript." article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Nicolò full_name: Zava, Nicolò id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad last_name: Zava orcid: 0000-0001-8686-1888 citation: ama: Zava N. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic & Geometric Topology. 2025;25(8):5153-5174. doi:10.2140/agt.2025.25.5153 apa: Zava, N. (2025). Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic & Geometric Topology. Mathematical Sciences Publishers. https://doi.org/10.2140/agt.2025.25.5153 chicago: Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” Algebraic & Geometric Topology. Mathematical Sciences Publishers, 2025. https://doi.org/10.2140/agt.2025.25.5153. ieee: N. Zava, “Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces,” Algebraic & Geometric Topology, vol. 25, no. 8. Mathematical Sciences Publishers, pp. 5153–5174, 2025. ista: Zava N. 2025. Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces. Algebraic & Geometric Topology. 25(8), 5153–5174. mla: Zava, Nicolò. “Coarse and Bi-Lipschitz Embeddability of Subspaces of the Gromov–Hausdorff Space into Hilbert Spaces.” Algebraic & Geometric Topology, vol. 25, no. 8, Mathematical Sciences Publishers, 2025, pp. 5153–74, doi:10.2140/agt.2025.25.5153. short: N. Zava, Algebraic & Geometric Topology 25 (2025) 5153–5174. corr_author: '1' date_created: 2025-12-29T12:09:09Z date_published: 2025-11-20T00:00:00Z date_updated: 2026-01-05T12:19:09Z day: '20' ddc: - '500' department: - _id: HeEd doi: 10.2140/agt.2025.25.5153 external_id: arxiv: - '2303.04730' file: - access_level: open_access checksum: 1e05b4f17a44500ae1ae1e21bc636f6a content_type: application/pdf creator: dernst date_created: 2026-01-05T12:16:38Z date_updated: 2026-01-05T12:16:38Z file_id: '20943' file_name: 2025_AlgebraicGeomTopology_Zava.pdf file_size: 574389 relation: main_file success: 1 file_date_updated: 2026-01-05T12:16:38Z has_accepted_license: '1' intvolume: ' 25' issue: '8' language: - iso: eng month: '11' oa: 1 oa_version: Published Version page: 5153-5174 project: - _id: 26AD5D90-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: I04245 name: Algebraic Footprints of Geometric Features in Homology publication: Algebraic & Geometric Topology publication_identifier: eissn: - 1472-2739 issn: - 1472-2747 publication_status: published publisher: Mathematical Sciences Publishers quality_controlled: '1' scopus_import: '1' status: public title: Coarse and bi-Lipschitz embeddability of subspaces of the Gromov–Hausdorff space into Hilbert spaces tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 25 year: '2025' ... --- OA_type: closed access _id: '20868' abstract: - lang: eng text: Residents of low-latitude megacities face growing vulnerability to humid-heat stress under urbanization and global warming, yet limited research has assessed the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat exposures in these cities. Here we quantify the hospital admissions of MBDs in Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat, and project future burdens under various greenhouse gas (GHG)-emission and population scenarios. Humid heat drives a higher morbidity burden than high temperature alone, especially in humid-heat nights. Without population change, the humid-heat-related morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval 56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465 (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing emissions to the lowest pathway. With projected population decline, the attributable hospital admissions will decrease toward century’s end. These findings highlight the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme humid heat. acknowledgement: 'This research was supported by the National Natural Science Foundation of China (grants 42288101 and 42175066) and Shanghai International Science and Technology Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554), the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.' article_processing_charge: No article_type: original author: - first_name: Chen full_name: Liang, Chen last_name: Liang - first_name: Jiacan full_name: Yuan, Jiacan last_name: Yuan - first_name: Renhe full_name: Zhang, Renhe last_name: Zhang - first_name: Xu full_name: Tang, Xu last_name: Tang - first_name: Gunter full_name: Schumann, Gunter last_name: Schumann - first_name: Esther full_name: Hitchen, Esther last_name: Hitchen - first_name: Elli full_name: Polemiti, Elli last_name: Polemiti - first_name: Emin full_name: Serin, Emin last_name: Serin - first_name: Hedi full_name: Kebir, Hedi last_name: Kebir - first_name: Tristram A. full_name: Lett, Tristram A. last_name: Lett - first_name: Nilakshi full_name: Vaidya, Nilakshi last_name: Vaidya - first_name: Jean-Charles full_name: Roy, Jean-Charles last_name: Roy - first_name: Henrik full_name: Walter, Henrik last_name: Walter - first_name: Andreas full_name: Heinz, Andreas last_name: Heinz - first_name: Markus full_name: Ralser, Markus last_name: Ralser - first_name: Sven full_name: Twardziok, Sven last_name: Twardziok - first_name: Roland full_name: Eils, Roland last_name: Eils - first_name: Marcel full_name: Jentsch, Marcel last_name: Jentsch - first_name: Ulrike-Helene full_name: Taron, Ulrike-Helene last_name: Taron - first_name: Tatjana full_name: Schütz, Tatjana last_name: Schütz - first_name: Kerstin full_name: Schepanski, Kerstin last_name: Schepanski - first_name: Tobias full_name: Banaschewski, Tobias last_name: Banaschewski - first_name: Maja full_name: Neidhart, Maja last_name: Neidhart - first_name: Andreas full_name: Meyer-Lindenberg, Andreas last_name: Meyer-Lindenberg - first_name: Heike full_name: Tost, Heike last_name: Tost - first_name: Nathalie full_name: Holz, Nathalie last_name: Holz - first_name: Emanuel full_name: Schwarz, Emanuel last_name: Schwarz - first_name: Argyris full_name: Stringaris, Argyris last_name: Stringaris - first_name: Nina full_name: Christmann, Nina last_name: Christmann - first_name: Karina full_name: Janson, Karina last_name: Janson - first_name: Frauke full_name: Nees, Frauke last_name: Nees - first_name: Maja full_name: Neidhart, Maja last_name: Neidhart - first_name: Beke full_name: Seefried, Beke last_name: Seefried - first_name: Rieke full_name: Aden, Rieke last_name: Aden - first_name: Ole A. full_name: Andreassen, Ole A. last_name: Andreassen - first_name: Lars T. full_name: Westlye, Lars T. last_name: Westlye - first_name: Dennis full_name: van der Meer, Dennis last_name: van der Meer - first_name: Sara full_name: Fernández-Cabello, Sara last_name: Fernández-Cabello - first_name: Rikka full_name: Kjelkenes, Rikka last_name: Kjelkenes - first_name: Helga full_name: Ask, Helga last_name: Ask - first_name: Michael full_name: Rapp, Michael last_name: Rapp - first_name: Mira full_name: Tschorn, Mira last_name: Tschorn - first_name: Sarah Jane full_name: Böttger, Sarah Jane last_name: Böttger - first_name: Andre full_name: Marquand, Andre last_name: Marquand - first_name: Antoine full_name: Bernas, Antoine last_name: Bernas - first_name: Gaia full_name: Novarino, Gaia id: 3E57A680-F248-11E8-B48F-1D18A9856A87 last_name: Novarino orcid: 0000-0002-7673-7178 - first_name: Mel full_name: Slater, Mel last_name: Slater - first_name: Jaime full_name: Gallego, Jaime last_name: Gallego - first_name: Álvaro full_name: Pastor, Álvaro last_name: Pastor - first_name: Guillem full_name: Feixas, Guillem last_name: Feixas - first_name: Francisco José full_name: Eiroa-Orosa, Francisco José last_name: Eiroa-Orosa - first_name: Markus M. full_name: Nöthen, Markus M. last_name: Nöthen - first_name: Andreas J. full_name: Forstner, Andreas J. last_name: Forstner - first_name: Isabelle full_name: Claus, Isabelle last_name: Claus - first_name: Carina full_name: Mathey, Carina last_name: Mathey - first_name: Stefanie full_name: Heilmann-Heimbach, Stefanie last_name: Heilmann-Heimbach - first_name: Per full_name: Hoffmann, Per last_name: Hoffmann - first_name: Abigail full_name: Miller, Abigail last_name: Miller - first_name: Peter full_name: Sommer, Peter last_name: Sommer - first_name: Karen full_name: Schmitt, Karen last_name: Schmitt - first_name: Johannes full_name: Wilbertz, Johannes last_name: Wilbertz - first_name: Myrto full_name: Patraskaki, Myrto last_name: Patraskaki - first_name: Viktor full_name: Jirsa, Viktor last_name: Jirsa - first_name: Spase full_name: Petkoski, Spase last_name: Petkoski - first_name: Anastasios-Polykarpos full_name: Athanasiadis, Anastasios-Polykarpos last_name: Athanasiadis - first_name: Bernhard full_name: Spanlang, Bernhard last_name: Spanlang - first_name: Charlie full_name: Pearmund, Charlie last_name: Pearmund - first_name: Sören full_name: Hese, Sören last_name: Hese - first_name: Paul full_name: Renner, Paul last_name: Renner - first_name: Tianye full_name: Jia, Tianye last_name: Jia - first_name: Xiao full_name: Chang, Xiao last_name: Chang - first_name: Yuxiang full_name: Dai, Yuxiang last_name: Dai - first_name: Yunman full_name: Xia, Yunman last_name: Xia - first_name: Yuzhu full_name: Li, Yuzhu last_name: Li - first_name: Yanqing full_name: Zhang, Yanqing last_name: Zhang - first_name: Vince full_name: Calhoun, Vince last_name: Calhoun - first_name: Paul full_name: Thompson, Paul last_name: Thompson - first_name: Nicholas full_name: Clinton, Nicholas last_name: Clinton - first_name: Sylvane full_name: Desrivières, Sylvane last_name: Desrivières - first_name: Kofoworola full_name: Agunbiade, Kofoworola last_name: Agunbiade - first_name: Xinyang full_name: Yu, Xinyang last_name: Yu - first_name: Zuo full_name: Zhang, Zuo last_name: Zhang - first_name: Di full_name: Chen, Di last_name: Chen - first_name: Allan H. full_name: Young, Allan H. last_name: Young - first_name: Ameli full_name: Schwalber, Ameli last_name: Schwalber - first_name: Vanessa full_name: Köhler, Vanessa last_name: Köhler - first_name: Bernd full_name: Stahl, Bernd last_name: Stahl - first_name: George full_name: Ogoh, George last_name: Ogoh - first_name: Tamara full_name: Schikowski, Tamara last_name: Schikowski - first_name: Ragnhild full_name: Brandlistuen, Ragnhild last_name: Brandlistuen citation: ama: Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 2025;3(12):1532-1544. doi:10.1038/s44220-025-00519-y apa: Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen, R. (2025). Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. Springer Nature. https://doi.org/10.1038/s44220-025-00519-y chicago: Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” Nature Mental Health. Springer Nature, 2025. https://doi.org/10.1038/s44220-025-00519-y. ieee: C. Liang et al., “Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai,” Nature Mental Health, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025. ista: Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N, Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G, Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S, Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V, Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T, Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 3(12), 1532–1544. mla: Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” Nature Mental Health, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:10.1038/s44220-025-00519-y. short: C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti, E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser, S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski, M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen, L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater, J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner, I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer, K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis, B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia, Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade, X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh, T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544. date_created: 2025-12-29T12:11:28Z date_published: 2025-12-01T00:00:00Z date_updated: 2026-01-05T12:02:29Z day: '01' department: - _id: GaNo doi: 10.1038/s44220-025-00519-y intvolume: ' 3' issue: '12' language: - iso: eng month: '12' oa_version: None page: 1532-1544 project: - _id: 349d1832-11ca-11ed-8bc3-d79b574010e0 grant_number: '101057429' name: Reducing the impact of major environmental challenges on mental health publication: Nature Mental Health publication_identifier: issn: - 2731-6076 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 3 year: '2025' ...